| Document | Document Title |
|---|---|
| US08736359B2 |
Signal processing method, information processing apparatus, and storage medium for storing a signal processing program
This invention provides a signal processing technique of suppressing various kinds of noise including unknown noise without storing a number of pieces of noise information in advance. To accomplish this, noise information is modified using modification information to obtain modified noise information. The noise in the noisy signal is suppressed using the modified noise information. The modification information is adapted and updated for the result of the step of suppressing. |
| US08736358B2 |
Current source with tunable voltage-current coefficient
A current source providing an output current with a fixed current range includes a bias circuit, a resistor, a current mirror, and a controller. The bias circuit provides a first voltage weighted with a first tunable coefficient and a second voltage weighted with a second tunable coefficient. The resistor has a tunable resistance for determining a bias current according to a voltage difference between the first and the second voltages and the tunable resistance. The current mirror generates the output current according to the bias current. The controller adjusts the tunable resistance and one of the first and the second tunable coefficients to achieve a voltage-current coefficient with different values, while the bias current and the output current are kept within a fixed current range. |
| US08736357B2 |
Method of generating multiple current sources from a single reference resistor
A differential voltage controlled current source generating one or more output currents is based upon a single external resistor. The differential voltage controlled current source may generate an output current that is proportional to a received differential voltage and a bias current with the use of a single external resistor. The technique may be used to generate multiple accurate and process independent current sources. The current sources may be a zero temperature coefficient (ZTC) current, a proportional to absolute temperature (PTAT) current, or an inversely proportional to absolute temperature (NTAT) current. The output of the current sources may be inversely proportional to the resistance of the external resistor. |
| US08736353B2 |
Power supply for localized portions of an integrated circuit
System and method system for regulating voltage in a portion of an integrated circuit. An integrated circuit has a voltage input and at least a portion that is less than all of the integrated circuit, which requires a local voltage level. A voltage selector establishes a target voltage for the portion. A first comparator compares the target voltage to the local voltage and generates a pull up control signal when the local voltage is below the target voltage. A second comparator compares the target voltage to the local voltage and generates a pull down control signal when the local voltage is above the target voltage. A pull up device, responsive to the pull up control signal, increases the local voltage according to the pull up control signal. A pull down device, responsive to the pull down control signal, decreases the local voltage level according to the pull down control signal. |
| US08736352B2 |
Internal voltage generation circuit
An internal voltage generation circuit includes a pumping voltage generation unit configured to generate a pumping voltage when a first internal voltage has a lower level than a first reference voltage or a second internal voltage has a lower level than a second reference voltage, and a select transmission unit configured to selectively transmit the pumping voltage as the first internal voltage or the second internal voltage. |
| US08736350B2 |
Pressure enabling device and method and electronic apparatus containing the same
A pressure enabling apparatus includes: a pressure sensor, a resistance wire and a pressure setting module, wherein a terminal of the resistance wire is connected to the pressure sensor and another terminal thereof is connected to an electronic apparatus. The pressure setting module is provided for receiving and converting a resistance variation of the resistance wire into a pressure value. The pressure sensor is provided for varying the resistance value thereof according to an external pressure variation, wherein the resistance variation is processed and transmitted to the pressure setting module via the resistance wire. The electronic apparatus implements an application or function according to a pressure value of the pressure setting module. An electronic apparatus is also provided for implementing different applications by pressing the electronic apparatus and for setting numbers or pages when an application of music-playing or document-reading is locked. |
| US08736347B2 |
Adjustable power splitter and corresponding methods and apparatus
An adjustable power splitter includes: a power divider with an input and a first and second divider output; a first adjustable phase shifter and first adjustable attenuator series coupled to the first divider output and providing a first power output; a second adjustable phase shifter and second adjustable attenuator series coupled to the second divider output and providing a second power output; an interface; and a controller. The controller is configured to receive, via the interface, data indicating phase shifts to be applied by the first and second adjustable phase shifters and attenuation levels to be applied by the first and second adjustable attenuators, and to control, based on the data, the phase shifts and attenuation levels applied by the first and second adjustable phase shifters and the first and second adjustable attenuators. |
| US08736345B2 |
Systems and methods of level shifting for voltage drivers
System and method for controlling one or more switches. The system includes a first converting circuit, a second converting circuit, and a signal processing component. The first converting circuit is configured to convert a first current and generate a first converted voltage signal based on at least information associated with the first current. The second converting circuit is configured to convert a second current and generate a second converted voltage signal based on at least information associated with the second current. The signal processing component is configured to receive the first converted voltage signal and the second converted voltage signal and generate an output signal based on at least information associated with the first converted voltage signal and the second converted voltage signal. |
| US08736343B2 |
Signal isolators using micro-transformers
A logic signal isolator comprising a transformer having a primary winding and a secondary winding; a transmitter circuit which drives said primary winding in response to a received logic signal, such that in response to a first type of edge in the logic signal, a signal of a first predetermined type is supplied to the primary winding and in response to a second type of edge in the logic signal, a signal of a second predetermined type is supplied to said primary winding, the primary winding and the transmitter being referenced to a first ground; and the secondary winding being referenced to a second ground which is galvanically isolated from the first ground and said secondary winding supplying to a receiver circuit signals received in correspondence to the signals provided to the primary winding, the receiver reconstructing the received logic signal from the received signals. |
| US08736341B2 |
Semiconductor apparatus having multiple chips mounted thereon
A semiconductor apparatus includes a first chip and a second chip mounted on the first chip. The first chip includes a first port that receives an operation clock signal, and a first circuit that operates in synchronization with the operation clock signal. The second chip includes a delay control part that generates a delay control signal indicating a delay amount based on a cycle of a reference clock signal, plural delay circuits that are connected in multiple stages and delay clock signals input to the plural delay control circuits based on the delay control signal and sequentially output the delayed clock signals to a subsequent stage, and a second port that is connected to the first port and receives the operation clock signal based on the delayed clock signals output from the plural delay circuits. |
| US08736339B2 |
Clock distribution circuit and method of forming clock distribution circuit
This invention includes a clock tree to which clock signals are distributed, and a phase comparison circuit configured to detect the phase difference between a plurality of feedback clock signals upon receiving the plurality of feedback clock signals output from different branching points of the clock tree. The invention includes a feedback clock signal generation circuit configured to generate a variation-corrected feedback clock signal for correcting a manufacture variation in the semiconductor integrated circuit based on the phase difference detected by the phase comparison circuit. The invention includes a phase regulation circuit configured to delay the clock signal so as to reduce the phase difference between a reference clock signal and the variation-corrected feedback clock signal generated by the feedback clock signal generation circuit. |
| US08736338B2 |
High precision single edge capture and delay measurement circuit
A method and circuit for providing on-chip measurement of the delay between two signals includes first and second delay chains (241, 242) having different delay values connected to sampling latches (222-227) which each include a data input coupled between adjacent delay elements of the first delay chain and a clock input coupled between adjacent delay elements of the second delay chain, thereby capturing a high precision delay measurement for the signals. |
| US08736329B1 |
Systems and methods for providing duty cycle correction
Systems and methods are disclosed including a duty cycle module having two timer circuits to measure pulse widths of a clock signal. Two comparators are used to generate control signals depending upon comparisons of the pulse width measurements. In response to the control signals, either the clock signal or an inverted clock signal may be programmably delayed such that combination of the clock signal and the inverted clock signal results in a corrected clock signal. Systems and methods are also disclosed for verifying operation of a duty cycle module. |
| US08736327B2 |
Time-to-digital converter
A TDC circuit include: a first delay circuit having first inverting delay devices connected to form a loop, the first inverting delay devices outputting a inverted signal according to an input signal after a first signal delay period; a second delay circuit having second inverting delay devices connected to form a loop, the second inverting delay according to an input signal after a second signal delay period different from the first signal delay period; first flip-flop circuits that latch the logical values of third pulse signals including the first pulse signal output from the first inverting delay devices based on fourth pulse signals including the second pulse signal or pulse signals; a first counter that counts the third pulse signal; a second counter that counts the fourth pulse signal; and a detection result output circuit that stores the count from the first counter and the count from the second counter. |
| US08736324B2 |
Differentiator based spread spectrum modulator
A spread spectrum clock generator which includes a pulse train generator circuit and a modulating circuit configured to produce a modulating signal relating to a time derivative of an output of the pulse train generator circuit. In one embodiment the modulating circuit includes a active differentiator circuit and in another embodiment the modulating circuit includes a passive differentiator circuit. A modulator is included which is configured to produce a spread spectrum clock output which is frequency modulated by the modulating signal. |
| US08736321B2 |
Transmission/reception device and information processing device
A transmission/reception device includes a transmission circuit configured to apply a delay to at least one of a positive signal and a negative signal of differential signals to be sent to another device, detect a direction of a differential signal skew between the positive signal and the negative signal, to at least one of which the delay is applied, and control the delay in a manner as to reduce the differential signal skew; and a reception circuit configured to apply a delay to at least one of a positive signal and a negative signal of differential signals sent from another transmission/reception device, detect a direction of a differential signal skew between the positive signal and the negative signal, to at least one of which the delay is applied, and control the delay in a manner as to reduce the differential signal skew. |
| US08736319B2 |
Power on reset circuit and method of use
The disclosed power-on reset circuit provides an indication of when and whether a supply voltage Vdd has reached a trigger voltage level Vtrig. The disclosed circuit includes a flip-flop circuit and a first comparator circuit. The circuit according to the invention has a D input node of the flip-flop circuit coupled to the supply voltage. The first comparator circuit outputs a clock signal, where the flip-flop circuit is clocked by the clock signal. A Q output node of the flip-flop circuit provides the power-on reset signal, where the power-on reset signal is in a LO state when the supply voltage is at a voltage level that is less than the trigger voltage level Vtrig. The power-on reset signal is in a HI state when the supply voltage is at a voltage level that is greater than the trigger voltage level Vtrig. |
| US08736316B2 |
Current driver with output current clamping
In one aspect, a current driver, includes an operational amplifier that includes a first input port configured to receive a reference signal and a second input port configured to receive a variable signal. The variable signal is a function of an output current of the current driver. The reference signal corresponds to a selected maximum output current of the current driver. The current driver also includes a feedback transistor comprising a gate coupled to the output of the operational amplifier and a summing junction coupled to a drain of the feedback transistor and configured to receive a signal from the drain to enable clamping of the output current of the current driver to the maximum output current when the variable signal exceeds the reference signal. The summing junction is coupled to a set of transistors configured to provide the output current of the current driver. |
| US08736315B2 |
Semiconductor device
Provided is a semiconductor device exemplified by an inverter circuit and a shift register circuit, which is characterized by a reduced number of transistors. The semiconductor device includes a first transistor, a second transistor, and a capacitor. One of a source and a drain of the first transistor is electrically connected to a first wiring, and the other thereof is electrically connected to a second wiring. One of a source and a drain of the second transistor is electrically connected to the first wiring, a gate of the second transistor is electrically connected to a gate of the first transistor, and the other of the source and the drain of the second transistor is electrically connected to one electrode of the capacitor, while the other electrode of the capacitor is electrically connected to a third wiring. The first and second transistors have the same conductivity type. |
| US08736312B2 |
Systems and methods for compensating the input offset voltage of a comparator
Systems and methods of actively compensating for the input offset voltage of a comparator are provided. A compensation circuit may include a compensation comparator for comparing the comparison signal generated using the output signal of a comparator, to a reference voltage. A first voltage accumulator is coupled to the compensation comparator and produces a first voltage that is related to a first amount of time that the comparison signal spends above the reference voltage. A second voltage accumulator is coupled to the compensation comparator, and produces a second voltage that is related to the second amount of time that the comparison signal spends below the reference voltage. The first voltage and/or the second voltage may be used to provide one or more compensation signals to one or more of the two input terminals of the comparator. |
| US08736310B2 |
Comparator with offset compensation and improved dynamic range
A comparator having first and second stages can provide component offset compensation and improved dynamic range. The first stage can receive first and second input signals and produce first and second output signals. The second stage can be coupled to the first stage to receive the first and second output signals at first and second input terminals of the second stage. The second stage can provide a voltage to the first and second terminals that differs from the supply voltage by less than a voltage of a diode drop. The comparator is operable to receive input voltages that reach the supply voltage. |
| US08736307B2 |
Bidirectional transceiver and method
In accordance with an embodiment, a transceiver includes a bidirectional data transmission circuit coupled to a direction control circuit and method for transmitting electrical signals in one or more directions. The direction control circuit generates a comparison signal in response to comparing input/output signals of the bidirectional data transmission circuit. Transmission path enable signals are generated in response to the comparison signal. |
| US08736304B2 |
Self-biased high speed level shifter circuit
A method and apparatus for translating signals between different components located in different power boundaries in a mixed voltage system. A level shifter system includes a first level shifter circuit connected to a first voltage source. A second level shifter circuit connects to a second voltage source. An intermediate level shifter circuit has an input that connects to the output of the first level shifter circuit. The output of the intermediate level shifter circuit connects to the input of the second level shifter circuit. The intermediate level shifter circuit uses an intermediate voltage source having an intermediate voltage about midway between the first voltage of the first voltage source and the second voltage of the second voltage source. |
| US08736301B2 |
System on chip and control module therefor
A System on a Chip (SoC) has a first set of switches, each having first terminals for routing SoC signals and a second terminal, and a second set of switches. Each switch of the second set of switches has third terminals for routing signals with the first set of switches, and a fourth terminal. A SoC control module defines a switching configuration, and includes a first memory portion for storing a first switching protocol for the first set of switches. This defines, for a switch of the first set of switches, an electrical path between one of the first terminals and the second terminal. A second memory portion stores a second switching protocol for the second set of switches, and defines, for a switch of the second set of switches, an electrical path between one of the third terminals and the fourth terminal. |
| US08736300B2 |
In-circuit data collection using configurable selection networks
In one general aspect, a data collection system for a circuit under test implemented as an integrated circuit or using a programmable logic device is disclosed. It comprises a configurable selection network connected to debug nodes of the circuit. The selection network can be reconfigured after implementation of the circuit to route data from selectable debug nodes in the circuit under test to a controller to allow analysis of the circuit. The data collection system can further comprise a configurable data packer. A method of use of the system associates data from the debug nodes with individual debug nodes of the circuit based on a configuration of the configurable selection network or that of the configurable data packer or both. The method and system of the invention allows for efficient data collection from different sets of debug nodes without having to re-implement the circuit. |
| US08736299B1 |
Setting security features of programmable logic devices
Systems and methods are disclosed for allowing security features to be selectively enabled during device configuration. For example, a programmable integrated circuit device is provided that receives configuration data and security requirement data. Control circuitry compares enabled security features in the device against the security requirements, and can configure the programmable integrated circuit device with the configuration data or prevent such configuration. Control circuitry may also use the security requirement data to set security features within the device. |
| US08736298B2 |
Method for detecting a step loss condition
A method for detecting and correcting for a step loss condition. A back electromagnetic force signal is measured and compared to a reference voltage. The motor continues operating and the back electromagnetic force signal is measured again and compared to the reference voltage. If the measured levels of the back emf voltages are less than the reference voltage, a step loss condition has occurred and the stator field is repositioned. |
| US08736297B2 |
Method for production of a fault signal, and an electrical protective device
A fault signal indicates a single-pole or a double-pole fault in a three-phase electrical power grid which occurred during a present electric oscillation in the electrical power grid. The method assures that single-pole or double-pole faults occurring during oscillation can be detected with high reliability in that a symmetry signal is produced during the oscillation, which indicates whether the oscillation is symmetrical or unsymmetrical, and the phases of the electrical power grid are checked for an existing fault, wherein the symmetry signal is used for carrying out the check. The fault signal is produced if a fault was detected during the check. A protective device has an accordingly equipped control unit. |
| US08736294B2 |
Probe card stiffener with decoupling
A stiffener for a probe card assembly can include decoupling mechanisms disposed within radial arms of the stiffener. The decoupling mechanisms can be compliant in a direction along a radial direction of said radial arm and rigid in a direction perpendicular to said radial arm. The decoupling mechanisms can decouple the stiffener from thermally induced differential radial contraction and expansion of the stiffener relative to the cardholder to which the stiffener is mounted. This can reduce thermally-induced vertical translation of the probe card assembly. |
| US08736292B2 |
Probe card and inspection apparatus
An automatic switching mechanism is controlled by a probe card independent from a tester without limitation of the number of control signals from the tester. A probe card and an inspection apparatus include probes to be brought into contact with electrodes of inspection targets and a power supply channel electrically connecting the probes to a tester. The automatic switching mechanism divides each of the power supply channels into a plurality of power supply wiring portions, which are respectively connected to the probes; and shuts off the power supply wiring responsive to electrical fluctuation such as overcurrent. An electrical fluctuation detection mechanism detects an electrical fluctuation due to a defective product among the inspection targets. A control mechanism, responsive to detection of an electrical fluctuation, shuts off the power supply wiring portion if the electrical fluctuation is caused by the automatic switching mechanism. |
| US08736289B2 |
Burn-in test apparatus with function of energy recycling
A new electrical recycling apparatus for AC/DC power converter is provided to recycle the electricity in direct current to the input ends of the power converter to be tested to save a stage of power converter and avoid the complicated standard and requirement that feed the electricity to the mains supply. |
| US08736287B2 |
Conductance detection system and method
A detection system and method for detecting one or a plurality of species from a mixture of species in a phase. The detection system and method detect changes in conductance induced by the species. The conductance includes a cell structure having a rigid architecture having a top surface a portion of which is electrically conductive forming a first conductive component. A second conductive component substantially overlaps the first conductive component and is spaced from the first conductive component by an insulating component. One or more flow pathways exist between the first conductive component and the second conductive component for the chemical and/or biological species to flow. A time dependent electrical signal for inducing a time dependent response is applied to at least one of said first and second conductive components and a signal detector coupled to at least one of the first and second conductive components measures the time dependent response. |
| US08736283B2 |
Advanced obscured feature detector
A surface-conforming obscured feature detector includes a plurality of sensor plates, each having a capacitance that varies based on the dielectric constant of the materials that compose the surrounding objects and the proximity of those objects. A sensing circuit is coupled to the sensor plates 32 to measure the capacitances of the sensor plates. A controller is coupled to the sensing circuit to analyze the capacitances measured by the sensing circuit. One or a plurality of indicators are coupled to the controller, and are selectively activated to identify the location of an obscured feature behind a surface. |
| US08736276B2 |
Ripple spring and diagnostic method therefor
A ripple spring is provided having one or more conductive layers, and one or more non-conductive layers. The conductive layers and the non-conductive layers are laminated together to form a symmetrical stack of layers. A method is also provided for monitoring the ripple spring. The method includes the steps of providing a ripple spring that holds a winding in place, where the ripple spring is positioned at least partially within a stator slot defined within an electromechanical device. Providing a conductive layer disposed within the ripple spring, and generating signals from the conductive layer, the signals corresponding to at least one aspect of the ripple spring. An analyzing step analyzes the signals to determine the at least one aspect of the ripple spring, wherein the at least one aspect facilitates an identification of faults in the ripple spring. |
| US08736268B2 |
Device for correcting set-point signals and system for the generation of gradients comprising such a device
A device for real-time correction of set-point signals intended to receive at the input set-point signals and to deliver at its output set-point signals that are modified to compensate for defects, negative effects or the like subsequently encountered during the processing and/or the application of the set-point signals. This device (1) includes at least one circuit (1′) that is based on a microprogrammed structure and composed of several subassemblies (3, 4, 5, 6, 6′) that work with digital components essentially including a micro-sequencer (3) forming a counter, a memory (4) for storing micro-instructions, and a processing unit (5) combined with at least one working memory (6, 6′) and integrating arithmetic calculation modules (7,7′), whereby the processing unit (5) modifies the data of set-point signals in accordance with the micro-instructions that are addressed by the micro-sequencer (3) and by taking into account the correction coefficients that are provided. |
| US08736264B2 |
NMR logging apparatus
Technologies including NMR logging apparatus and methods are disclosed. Example NMR logging apparatus may include surface instrumentation and one or more downhole probes configured to fit within an earth borehole. The surface instrumentation may comprise a power amplifier, which may be coupled to the downhole probes via one or more transmission lines, and a controller configured to cause the power amplifier to generate a NMR activating pulse or sequence of pulses. Impedance matching means may be configured to match an output impedance of the power amplifier through a transmission line to a load impedance of a downhole probe. Methods may include deploying the various elements of disclosed NMR logging apparatus and using the apparatus to perform NMR measurements. |
| US08736258B2 |
Method and device for contactless sensing rotation and angular position using orientation tracking
1. Method and device for contactless sensing rotation and angular position using orientation tracking. 2.1 To improve the accuracy and possible resolution of a magnetic positioning system, a method and a device using a special tracking technique is proposed. 2.2. The method and the device are using multiple magnetic field sensing elements at different positions below a magnetic target. The sensed signals are used to select or combine the sensing elements for a best approach to the actual orientation of the magnet. This allows putting out the related orientation of the approach as a coarse value and the remaining displacement as a fine value. 2.3. A device using this method allows highly accurate measurement of angular positions controlling or tolerating the placement of a magnet as the input source. |
| US08736255B2 |
Sensor arrangement and method for determining the position and/or change in position of a measurement object
A sensor arrangement for determining the position and/or change in position of a measurement object relative to a sensor, wherein a magnet is assigned to the measurement object, is configured, with respect to the design of an operationally reliable sensor with low production costs, such that the sensor has a first conductor and a second conductor which is arranged alongside the first conductor and such that a magnetically soft film is arranged in the area of influence of the first and second conductors, the permeability of which film changes under the influence of a magnetic field and which film influences the electromagnetic coupling between the first and second conductors. A corresponding method is specified. |
| US08736254B2 |
Physical quantity sensor and electronic apparatus
A physical quantity sensor includes a first rocking body and a second rocking body. Each of the rocking bodies is supported on a substrate by a first supporting portion and a second supporting portion. The first rocking body is partitioned into a first region and a second region by a first axis (supporting axis) when viewed in plane, and the second rocking body is partitioned into a third region and a fourth region by a second axis (supporting axis) when viewed in plane. The mass of the second region is larger than the mass of the first region, and the mass of the third region is larger than the mass of the fourth region. An arranged direction of the first region and the second region is the same as an arranged direction of the third region and the fourth region. |
| US08736252B2 |
Manipulation assembly for online electrical system test probe installation
An apparatus for online partial discharge testing includes a split-core radio-frequency current transformer sensor, an actuation subassembly, and a biasing member. The current transformer sensor has a first portion, a second portion, and a sensor hinge operably engaged between the first portion and the second portion. The actuation subassembly includes an elongate first member secured to the first portion of the current transformer sensor, a second member secured to the second portion of the current transformer sensor and configured to be movable relative to the first member, and a third member engaged with the second member and configured to translate along a length of the first member. The biasing member is configured to pivotally bias the first portion and the second portion of the current transformer sensor toward each other relative to the sensor hinge, with the biasing member secured relative to the first member. |
| US08736251B2 |
Digital sensing apparatus and digital readout module thereof
A digital sensing apparatus includes a sensing unit capable of providing a sensing response associated with an environmental parameter, and a digital readout module including a reading unit for generating a pulse signal having a pulse width associated with the sensing response, and a converting unit. The converting unit includes a clock signal generator for generating a variable-frequency clock signal, and a counter operable to count a width value of the pulse width of the pulse signal using the clock signal, so as to generate a digital sensing code. The frequency of the clock signal from the clock signal generator is adjustable to adjust resolution of the width value of the pulse width of the pulse signal. |
| US08736249B2 |
High frequency power detector circuit and radio communication device
A first envelope detector circuit and a second envelope detector circuit are the same in circuit configuration, where the former detects an input high frequency signal, and the latter generates a reference voltage for power level detection. A detector detects an output voltage of a selector configured to select an output of the first envelope detector circuit with reference to an output voltage of a selector configured to select an output of the second envelope detector circuit. A controller controls an input selector to determine and store control values for the two selectors during input of a high frequency reference signal generated by a high frequency reference signal generating unit, and controls the two selectors by using the stored control values when an actual high frequency signal is input. |
| US08736247B2 |
Power supply circuit and control method of controlling the power supply circuit
A power supply circuit is provided which includes a first booster to boost a power supply voltage supplied from a battery and generate a first boosted voltage, a second booster to boost the power supply voltage at a higher multiplication factor than the first booster and generate a second boosted voltage, a power supply selection circuit to output the first boosted voltage or the second boosted voltage, a first smoothing capacitor placed at an output end of the power supply selection circuit, and a second smoothing capacitor placed at an output end of the second booster. |
| US08736238B2 |
Buck and buck/boost converter systems having auxiliary circuits and method thereof
The configurations of a buck type and a buck/boost type converter systems and a controlling method thereof are provided in the present invention. The proposed buck/boost type converter system includes a rectifier bridge, a first auxiliary circuit including a first unidirectional switch coupled to the rectifier bridge and a second unidirectional switch coupled to the first unidirectional switch, a first capacitor coupled to the first unidirectional switch and the rectifier bridge, a buck/boost converter having a first input terminal coupled to the first unidirectional switch, a second input terminal coupled to the first capacitor, a first output terminal coupled to the second unidirectional switch and a second output terminal, a second capacitor electrically connected to the first and the second output terminals in parallel, and a DC source coupled to the second unidirectional switch. |
| US08736235B2 |
Power generation motor control system
A power-generation motor control system is a control system that controls a power-generation motor provided with an armature and a magnetic-field winding, and is characterized in that when the power-generation motor is operated as a motor, before a power source energizes the armature, a preliminary excitation current, with the value of which the induction voltage across the armature does not exceed the voltage of the power source, is applied to the magnetic-field winding in accordance with the rotation speed of the power-generation motor so that preliminary excitation of the power-generation motor is performed. |
| US08736229B2 |
Battery control circuit for reducing power consumption
A battery control circuit includes a voltage detection circuit for measuring voltages of electric cells, balancing circuits for balancing the voltages or SOCs of the electric cells, a signal input/output circuit for communicating with the outside, a power supply circuit having two modes: a normal mode and a low consumption mode, and a time management circuit. It receives a signal containing a period of time until the shift of the power supply circuit from the normal mode to the low consumption mode, and stores it in the time management circuit. If a command from the outside has not been sent for a predetermined period of time or when an operation stop command has been sent from the outside, the time management circuit causes the power supply circuit to continuously operate in the normal mode. Then, the battery control circuit monitors an operation continuation period in the normal mode, and causes the power supply circuit to shift to the low consumption mode when the operation continuation period matches the stored period of time. |
| US08736228B1 |
Charging an electronic device including traversing at least a portion of a path with an apparatus
A robotic device can provide power management and other functionality for various electronic devices. An electronic device and the robotic device can communicate information such as device charge level, relative position and rate of power consumption and can determine an appropriate time at which the robotic device should cause the electronic device to be charged, either by charging the device directly or transporting the device to an appropriate charger. The robotic device can also cause other functions to be performed as well, such as to enable high-bandwidth data transfer or perform resource-intensive activities when in communication with the electronic device. The robotic device can transport the electronic device to specific locations or to specific users, or as otherwise appropriate. |
| US08736224B2 |
Charging a battery using a circuit having shared loads
A method for charging an electric storage battery in a plug-in hybrid electric vehicle through a power supply circuit, includes coupling the charger to the circuit, determining whether another appliance in the circuit other than the charger is drawing current, determining a maximum charge rate at which the battery can be charged using the charger, charging the battery at the maximum charge rate if no other appliance in the circuit is drawing current, and charging the battery at less than the maximum charge rate if another appliance in the circuit is drawing current. |
| US08736223B2 |
Watercraft cover having integrated solar powered charging component and mateable assembly
Disclosed herein is a vehicle or watercraft cover that includes a solar battery charging component integrated therewith or attached thereto. Also disclosed is a kit for easily adapting a vehicle or watercraft to connect with a solar battery charging component. |
| US08736222B2 |
Flux controller for induction motor
Disclosed is a flux controller for maintaining reliable flux estimation performance in a low velocity region, the controller including a velocity controller, a torque current controller for outputting a torque voltage command, a flux controller for outputting a flux current command, a flux current controller for receiving the flux current command to output a flux voltage command, a three-phase converter for converting the torque voltage command and the flux voltage command into a three-phase voltage command applied to the induction motor to output the three-phase voltage command, a flux estimator for outputting a rotating angle of a rotor of the induction motor, an estimated flux value of the rotor and an estimated velocity of the rotor, and a flux regulator for receiving the torque voltage command and the estimated velocity to output a gain value that regulates a magnitude of the flux command. |
| US08736216B2 |
Electric drive with electronically scalable reconfigurable winding
A stator phase circuit for an electric machine includes a phase winding circuit including a plurality of series coupled sub-winding circuits, each sub-winding circuit includes a respective sub-winding coupled in parallel across a respective first controllable switch. |
| US08736213B2 |
Motor position controller
The motor position controller inputs a command pulse signal and a desired pulse form setting, and drives a motor based on the command pulse signal. The motor position controller includes a position command generating device configured to generate a position command signal from the command pulse signal in accordance with the inputted desired pulse form setting, a motor controlling part configured to supply power to the motor based on the position command signal, and a first conformity determination device configured to determine the conformity of the desired pulse form setting and the command pulse signal. |
| US08736206B2 |
Power converting apparatus
A power converting apparatus including a power converter that converts a DC voltage into an AC voltage and applies the AC voltage to an AC rotating machine and a control unit that controls the power converter based on an operation command from the outside is provided. The power converting apparatus includes: a first calculating unit that calculates and outputs, from a d-axis current detection value and a q-axis current detection value detected by the AC rotating machine and current command values based on the operation command, first voltage command values to the power converter, magnetic fluxes of the AC rotating machine, and an angular frequency; and a second calculating unit that sets, as an initial value, at least one of the magnetic fluxes and the angular frequency input from the first calculating unit and calculates and outputs second voltage command value to the power converter and an angular frequency. |
| US08736203B2 |
Inverter/charger integrated device and method for controlling the same
An inverter/charger integrated device is provided. The inverter/charger integrated device includes: a three-phase motor; a rectifying unit configured to rectify AC power for charging a battery and output the rectified AC power to a neutral point of the three-phase motor; a rectifier/inverter integrated unit configured to be connected to the rectifying unit and charge the battery; and a control unit configured to control the charging of the battery and an operation of the three-phase motor. |
| US08736201B2 |
Drive control circuit for linear vibration motor
In a drive control circuit of a linear vibration motor, a drive signal generating unit generates a drive signal used to alternately deliver a positive current and a negative current to a coil. A driver unit generates a drive current in response to the drive signal generated by the drive signal generating unit and supplies the drive current to the coil. An induced voltage detector detects an induced voltage occurring in the coil. After a running of the linear vibration motor has terminated, the drive signal generating unit generates a drive signal whose phase is opposite to that of the drive signal generated during the motor running; this drive signal of opposite phase includes a high impedance period during which the driver unit is controlled to a high impedance state. The induced voltage detector detects the induced voltage occurring in the coil during the high impedance period. |
| US08736198B2 |
Circular accelerator and its operation method
A circular accelerator comprises a target current value memory which stores a target current value of a beam current of charged particle which is extracted from an extracting device; and a frequency determination part in which a frequency change ratio is obtained by performing a feedback control based on an error signal between a detection signal of a beam current detector and a target current value which is stored in a target current value memory, and determines a subsequent frequency from the obtained frequency change ratio and a current frequency, wherein the subsequent frequency which is determined by the frequency determination part is stored in a frequency memory and a radio-frequency generator generates the subsequent radio-frequency of frequency which is determined. |
| US08736196B2 |
Backlight unit, method of operating the same and liquid crystal display device having the same
A backlight unit includes; a light source, an inverter which provides the light source with an input voltage, and a printed circuit board (“PCB”) connected to the light source, wherein the PCB includes a protection circuit which detects an open-lamp-protection voltage which varies according to a change of the input voltage and changes a reference voltage according to the change of the input voltage, wherein the protection circuit turns off the inverter when the detected open-lamp-protection voltage is higher than the changed reference voltage. |
| US08736194B2 |
LED dimmer circuit
A TRIAC dimmer gates an AC waveform from an AC power source in proportion to a control signal and outputs a TRIAC pulse having part of the waveform missing. The TRIAC pulse is rectified and is applied to an LED array and the drive current flowing to the LED array is detected at a current detection resistor. The drive current value and a predetermined value are compared at a comparator and in accordance with the comparison result thereof the control transistor is turned off. Then, the TRIAC pulse is converted to a DC voltage signal and in accordance with the obtained DC voltage signal the drive current value or the predetermined value input by the comparator are changed. Furthermore, instead of the TRIAC pulse, a PWM pulse supplied from an external source may also be utilized. |
| US08736191B2 |
Dimmer decoder with adjustable filter for use with LED drivers
A method includes receiving a sense signal having multiple pulses, where the sense signal is based on an output of a dimmer. The method also includes, for each of multiple sampling periods, (i) identifying at least one pulse duty cycle for at least one pulse in the sense signal during that sampling period and (ii) generating an output value identifying a duty cycle for driving one or more light emitting diodes (LEDs). The output value is based on the at least one pulse duty cycle. The method further includes filtering the output values using a filter and adjusting the filter based on a rate at which the output of the dimmer changes. The filter could be adjusted by controlling whether an additional resistor forms part of an RC filter based on a sampling state. |
| US08736189B2 |
Electronic ballasts with high-frequency-current blocking component or positive current feedback
Methods and apparatus are described that can provide improved power factor correction and total harmonic distortion, efficiency and/or direct feedback of load current variations to a power source inverter. In one example, a power supply, for example, a ballast, can have an input circuit, an output circuit and an inverter circuit coupled between the input circuit and the output circuit. A current feedback circuit is coupled between the output circuit and the inverter circuit and configured to feed current back to the inverter circuit through a transformer stage separate from the inverter as a function of a current level in the output circuit. |
| US08736188B2 |
Detector circuit and method for controlling a fluorescent lamp
A detector circuit for controlling at least one fluorescent lamp is provided, wherein the detector circuit is configured such that an inactive fluorescent lamp can be detected if a first signal is present at least one of a first input and a second signal is present at a second input in a detection interval after a start-up phase. |
| US08736182B1 |
Full wave low flicker LED light string
A split bridge circuit for rectifying the alternating current house supply into direct current (D.C.), using bi-polar transistor as rectifying devices. Using specified terminals of the bi-polar transistors results in a high forward voltage drop across the transistors (particularly as compared to the voltage drop across diode rectifiers in the prior art circuits), which reduces ripple significantly and lessens, or even eliminates, the need for a series limiting resistor in the circuit. |
| US08736181B2 |
AC driven light emitting device
There is provided an alternating current (AC) driven light emitting device including a plurality of LED arrays connected in series, each having a structure in which a plurality of LEDs are electrically connected to form a two-terminal circuit and emit light by a bidirectional voltage when an AC voltage is applied to the two-terminal circuit; and a switching device connected to at least one of the plurality of LED arrays and controlling a total driving voltage with respect to the plurality of LED arrays. The AC driven light emitting device permits operation from a low driving voltage Vf while having a high driving voltage at a high voltage Vf, thereby achieving excellence in terms of power factor, THD, and energy efficiency. |
| US08736179B2 |
Lighting apparatus with hybrid power supply device, and method utilizing the same
A light apparatus with a hybrid power supply device and method utilizing the same are disclosed. The light apparatus includes an LED module, a solar module, an auxiliary power module, a voltage level detection circuit, a first switch unit, and a second switch unit. When a voltage of a solar electric power generated by the solar module is greater than a predetermined value, the voltage level detection circuit provides an electrical connection between the solar module and the LED module for enabling a transmission of the solar electric power to the LED module. When the voltage of the solar electric power is smaller than the predetermined value, the voltage level detection circuit provides an electrical connection between the auxiliary power module and the LED module for enabling a transmission of an auxiliary electric power generated by the auxiliary power module to the LED module. |
| US08736178B2 |
LED lighting apparatus equipped with high-efficiency power supply
Disclosed is an LED lighting apparatus equipped with a high-efficiency power supply, capable of representing high power efficiency even in a low-power LED lighting apparatus by recycling a surplus voltage to charge a condenser, which supplies power to the controller, with the surplus voltage if the surplus voltage is generated from an LED acting as a load after a rectified voltage supplied to the LED has been consumed in the LED according to a design value. |
| US08736177B2 |
Compact RF antenna for an inductively coupled plasma ion source
An inductively coupled plasma ion source for a focused ion beam (FIB) system is disclosed, comprising an insulating plasma chamber with a feed gas delivery system, a compact radio frequency (RF) antenna coil positioned concentric to the plasma chamber and in proximity to, or in contact with, the outer diameter of the plasma chamber. In some embodiments, the plasma chamber is surrounded by a Faraday shield to prevent capacitive coupling between the RF voltage on the antenna and the plasma within the plasma chamber. High dielectric strength insulating tubing is heat shrunk onto the outer diameter of the conductive tubing or wire used to form the antenna to allow close packing of turns within the antenna coil. The insulating tubing is capable of standing off the RF voltage differences between different portions of the antenna, and between the antenna and the Faraday shield. |
| US08736176B2 |
Device and method for producing and/or confining a plasma
The invention relates to a device for producing and/or confining a plasma, said device comprising a chamber in the space of which the plasma is produced and/or confined, said chamber including a wall defining a housing inside the chamber and encompassing said space, wherein said device is characterized in that it comprises at least one assembly for producing and/or confining plasma, each assembly being composed of magnets having only an axial magnetization direction and being recessed in the wall defining the housing, so that the magnetization direction of all the magnets defining each assembly is substantially perpendicular to the housing defined by the wall and so that the assembly is substantially symmetrical to the housing, wherein the magnetic field lines do not extend through the wall of the chamber. The invention also relates to a method for producing and/or confining a plasma. |
| US08736169B2 |
Electron beam generating apparatus
An apparatus for generating an electron beam is disclosed to reduce emittance of an electron beam. The apparatus includes: a housing including a rear portion where an electron beam is generated, a front portion having an electron beam discharge hole for discharging the electron beam to the exterior, and a side portion connecting the rear portion and the front portion, the side portion having a first hole and an opposite side portion, facing the first hole, having a second hole in order to reduce asymmetry of an electric field caused by the first hole; and a waveguide installed on the side portion to supply an electromagnetic wave to the interior of the housing through the first hole, wherein the electron beam is generated by laser incident to the interior of the housing and accelerated by the electromagnetic wave supplied to the interior of the housing. |
| US08736165B2 |
Mercury-free discharge lamp having a translucent discharge vessel
A mercury-free discharge lamp with an electrical power consumption of less than 35 Watts may include a translucent discharge vessel which has a discharge space into which electrodes protrude for generating a gas discharge, wherein metal halides and ignition gas are contained in the discharge space, wherein the metal halides are present in a quantity in the range from 5 milligrams to 15 milligrams per 1 milliliter of discharge space volume in the discharge space. |
| US08736164B2 |
Organic EL panel comprising a light-emitting part and a sealing structure sealing the light-emitting part and method for manufacturing the same
An organic EL panel has a light-emitting part including one or a plurality of organic EL elements over a substrate and having a sealing structure sealing the light-emitting part. The organic EL element includes an organic layer formed on a first electrode, and a second electrode formed on the organic layer. The organic EL panel includes a coating film coating the light-emitting part. A contact object is arranged on an inner surface of the sealing structure. One or a plurality of convex parts is formed on the contact object. The coating film is formed to have a thickness larger than the length of the convex part. |
| US08736163B2 |
Organic electro-luminescence display device and method for fabricating the same
An organic electro-luminescence display device and a method for fabricating the same are provided. A first substrate and a second substrate are sealed by a sealant. An organic electro-luminescent diode is formed on the first substrate. The sealant contains a frit glass and a light-heat converter. The frit glass can reduce the moisture and oxygen transmission rate by preventing the organic electro-luminescent diode from being thermally decomposed during a curing process. Since the two substrates are encapsulated by the frit glass, the lifetime and reliability of the organic electro-luminescence display device can be increased. |
| US08736162B2 |
Flexible display panel and display apparatus including the flexible display panel
A flexible display panel including: a flexible substrate including a first region, second regions that extend from the first region and that have a curved surface, and a third region folded towards the second regions; a first display region in the first region of the flexible substrate; a second display region in the second regions of the flexible substrate; a plurality of non-display regions outside the first display region or the second display regions, wherein at least one of the plurality of non-display regions is in the third region of the flexible substrate; and an encapsulation member for encapsulating the first display region and the second display regions. |
| US08736157B2 |
Light-emitting element
To provide a light-emitting element with high emission efficiency or long lifetime, in which the use amount of a phosphorescent compound is small. To provide a light-emitting element including a light-emitting layer between a pair of electrodes, wherein the light-emitting layer includes a phosphorescent compound, a first organic compound, and a second organic compound, and the combination of the first organic compound and the second organic compound forms an exciplex. The light-emitting element transfers energy by utilizing the overlap between the emission spectrum of the exciplex and the absorption spectrum of the phosphorescent compound and thus has high energy transfer efficiency, even when the concentration of the phosphorescent compound is low. |
| US08736152B2 |
Piezoelectric vibrating pieces and associated devices exhibiting enhanced electrical field
An exemplary tuning-fork type piezoelectric vibrating piece has a rectangular base having upper and lower main surfaces and a pair of vibrating arms extending longitudinally from the base. The vibrating arms also have the upper and lower main surfaces. Each main surface of each vibrating arm defines a respective vibrating-arm groove extending longitudinally into the base. Each main surface of the base has at least one respective step-side surface situated outboard, in an X-axis direction, of each vibrating-arm groove. Each step-side surface is parallel with the respective vibrating-arm groove. A first electrode is situated on the vibrating-arm grooves of the first vibrating arm and on the at least one respective step-side surface on each main surface. A second electrode is situated on the vibrating-arm grooves of the second vibrating arm and on the at least one respective step-side surface on each main surface. The first and second electrodes are energized with different electrical polarities. |
| US08736149B2 |
Electronic component with metal plate above element and fabrication method of the same, and electronic device including the same
An electronic component includes: an element that is located on a substrate; a signal wiring that is located on the substrate and electrically connected to the element; a metal plate that is located so as to form a cavity on a functional part of the element and covers an upper surface of the cavity; a support post that is located on the substrate so as not to be located on the signal wiring, and supports the metal plate; and an insulating portion that covers the metal plate and the support post, and contacts a side surface of the cavity. |
| US08736146B2 |
Electric power device, electric power generation method, and production method of electric power device
There is provided a new self-generating electric power device using a piezoelectric element. An electric power device includes: a resonant portion that is secured at least at one end, receives waves propagating through a space or a medium and resonates; a piezoelectric element that is formed to connect to the resonant portion, and generates a voltage according to resonance of the resonant portion; and a first electrode and a second electrode that are formed on opposite surfaces of the piezoelectric element, and output the generated voltage. |
| US08736144B2 |
Vibration type driving apparatus
A vibrator according to an aspect of the present invention is provided with an adjustment region which is realized with use of an electro-mechanical energy conversion element that is designed for an adjustment on a resonance frequency, and an impedance element is arranged to be connected to the adjustment region. |
| US08736139B2 |
Optical image stabilizer and method of manufacturing the same
Disclosed herein is an optical image stabilizer, including: a substrate; a table disposed over the substrate, while levitating, to be movable on the substrate and having an image sensor mounted on the upper end of the substrate; cantilever arms disposed over the substrate, while levitating, and connected to the table to move the table; anchors fixing one ends of the cantilever arms onto the substrate; and electrodes applying voltage for moving the cantilever arm. |
| US08736138B2 |
Carbon nanotube MEMS assembly
A carbon nanotube MEMS assembly comprises a plurality of carbon nanotubes oriented into a patterned frame, the patterned frame defining at least two components of a MEMS device. An interstitial material at least partially binds adjacent carbon nanotubes one to another. At least one component of the frame is fixed and at least one component of the frame is movable relative to the fixed component. |
| US08736137B2 |
Wound field rotating machine with capacitive power transfer
An electrical rotating machine, such as a generator or motor, communicates power from a stationary location to the rotating rotor of the rotating machine via opposed pairs of capacitor plates, one plate of each pair rotating with the rotor and one plate of each pair fixed not to rotate. In one embodiment, separation between the plates of the pair is provided by a cushion of entrapped air. |
| US08736133B1 |
Methods and apparatus for overlapping windings
A first winding portion from a set of winding portions has a set of coils. Each coil of the first winding portion is associated with a different electrical phase from a set of electrical phases. Each coil of the first winding portion circumscribes a different area from a set of areas circumscribed by the set of coils of the first winding portion. A second winding portion has a set of coils associated with the set of electrical phases and a third winding portion has a set of coils associated with the set of electrical phases. The first winding portion at least partially overlaps the second winding portion and the third winding portion such that each area from the set of area is substantially circumscribed by a coil associated with each electrical phase from the set of electrical phases. |
| US08736132B2 |
Stator of rotating electrical machine
A turn part of a lead wire includes a projection part, a slope part and a second bent part. The projection part projects from a first slot to a direction parallel to an axial direction of the stator core. The slope part is diagonally extended at an angle of less than 90 degrees aiming to a Kth slot. The Kth slot is separated from the first slot at a specific interval via a first bent part that is bent in a circumferential direction from a tip of the projection part. The second bent part is connected with the slot accommodation part accommodated in the Kth slot, and is bent to the direction parallel to the axial direction of the stator core from a tip of the slope part. |
| US08736130B2 |
Segmented stator assemblies having end caps
Segmented stator assemblies having a plurality of stator segments and a plurality of end caps are disclosed. According to one example embodiment, a segmented stator assembly includes a plurality of stator segments and a plurality of end caps. Each stator segment has a yoke portion and a tooth portion extending from the yoke portion. Each end cap is positioned over one of the stator segments. Each end cap includes a body portion positioned at least partially over the yoke portion of its associated stator segment. At least one of the body portions includes at least a first post that cooperates with a post of an adjacent end cap to define a first wire management tie-down. The stator assembly further includes a stator wire coupled to the first wire management tie-down. Stator assemblies and end caps having other wire management and routing features are also disclosed. |
| US08736129B2 |
End caps for stator segments of segmented stator assemblies
An example end cap of a stator segment is provided for use in locating wires in a segmented stator assembly in desired positions. The end cap generally includes a body and an inboard wall. An identifier is defined by the inboard wall of the end cap for use in determining wire sizes to be used with the end cap. Terminal pockets are provided in the body for receiving the wires and making desired electrical connections, and steps located in the terminal pockets help secure the connectors in the terminal pockets. Plateaus, and troughs defined in the plateaus, are located outside the terminal pockets for use in trimming wires received in the terminal pockets as desired. And, retaining structures are located around the end cap to help with locating the wires in the desired positions. |
| US08736128B2 |
Three dimensional magnetic field manipulation in electromagnetic devices
Electromagnetic devices and near field plates for three-dimensional magnetic field manipulation are disclosed. In one embodiment, an electromagnetic device includes a rotor, a stator, and a magnetic field focusing device. The rotor may include a rotor body and a plurality of radially extending rotor poles. The stator may include a plurality of stator poles radially extending inwardly from a stator body toward the rotor body. Each stator pole may have a magnetic flux generating device and a stator pole tip, wherein an air gap may be located between each stator pole tip and each corresponding rotor pole. The magnetic field focusing device is coupled to at least one stator pole tip and produces a magnetic field profile having at least one concentrated magnetic flux region proximate the stator pole tip. The magnetic field focusing device twists the magnetic field profile by an angle α. |
| US08736124B2 |
Mounting bracket for motor
A mounting bracket for a motor, including a hoop structure and a plurality of mounting feet. The hoop structure includes a wall surface. The wall surface of the hoop structure includes the mounting feet formed by punching the wall surface of the hoop structure so that a plurality of grooves close to the mounting feet is produced on the wall surface of the hoop structure, and one end of each mounting foot is coupled to the wall surface of the hoop structure. The mounting bracket for a motor of the invention has a simple structure, low cost, and reliable connection and requires less material compared to conventional mounting brackets. The mounting bracket is suitable for different types of motors. |
| US08736122B2 |
Induction motor ventilated heat shield for bearings
A dynamoelectric machine, such as a totally enclosed fan cooled (TEFC) induction motor has a double-wall bearing housing heat shield that envelops and thermally isolates the bearing housing from the rest of the motor housing interior. The shield defines an air channel between the shield outer and inner walls. Optionally the air channel may be constructed to enable circulating air flow through a shield intake in communication with an air flow source, such as air ducted from the TEFC motor axial cooling fan. The air channel also defines an exhaust. Air flow within the air channel transfers heat out of the motor housing, lowering bearing housing operating temperature. Air flow rate may be varied in response to motor operational parameters. |
| US08736121B2 |
Linear vibrator
Disclosed is a linear vibrator including a fixing part providing an inner space of a predetermined size, at least one magnet disposed in the inner space of the fixing part to generate a magnetic force, a vibration part including a coil disposed to face the magnet to generate electromagnetic force by interacting with the magnet and a vibrating mass body, an elastic member coupled to the fixing part and the vibration part to provide an elastic force, and a substrate coupled to the vibration part and including a through hole through which the magnet passes to prevent the substrate from contacting the magnet when the vibration part is vibrated. |
| US08736112B2 |
Multi-terminal DC transmission system and method and means for control there-of
A method for controlling power flow within a multi-terminal DC power transmission system including two or more converter stations and the corresponding multi-terminal DC power transmission system are provided. The method includes the steps of: controlling the power flow to a steady state reference operating point for operating points within a control dead band defined for each respective converter station, and controlling the power flow by means of droop control in at least one of the converter stations upon detection of exceeding of an end point of one or more of the control dead bands. |
| US08736109B2 |
Powering a data center using multiple connections from a utility grid
A data center is electrically coupled to a power grid at two separate access points, which may be located within geographic proximity to each other. Each access point is located between two power generation systems. The access points have one or more power generation systems located between them, allowing the data center to be coupled to three or more power generation systems simultaneously and have access to power in the event of multiple power generation system failure. The data center may comprise two separate data center power inputs, which may each be connected to a separate power grid access point. The power grid may provide a high voltage level to the data center, and the data center may comprise transformers which step the voltage down to a lower voltage level. The data center may comprise one such transformer coupled to each of the two data center power inputs. The outputs of such transformers may be coupled together. |
| US08736107B1 |
Power source redundancy in a power supply
Disclosed are various embodiments of power source redundancy in a power supply for a rack mounted computing device. The power supply includes a plurality of AC power converters configured to receive power from corresponding power sources. A first AC power converter provides DC power to a common DC bus of the power supply. A second AC power converter provides DC power to the common DC bus in response to a change in the voltage level provided by the first AC power converter. |
| US08736103B2 |
Load control module for a generator and method of operation
A load control module is provided for use with a transfer switch apparatus that controls the delivery of standby electrical power to a load during utility power interruption. The load control module selectively brings loads online to receive standby electrical power to prevent overloading of the electric generator that is providing the standby electrical power. The frequency of the electrical power is also monitored and if a low frequency condition is detected, loads are taken offline (shed). A method to flag those loads that induce an overload condition is also provided. |
| US08736100B2 |
Ship
A ship that reduces the total amount of fossil fuels and other energy sources required, thereby saving energy. The ship (1) has a plurality of subsystems (10) constructed by dividing a network of power supply lines (3) and signal lines (4) into groups. The subsystems (10) consist of at least two subsystems among a bridge subsystem (10a) on the bridge; a propulsion subsystem (10b) in an engine room; a deck subsystem (10c) installed on a deck; a ballast cargo subsystem (10d) for ballasting and equipment installed in a hold; and an information processing subsystem (10e) corresponding to communication equipment. The subsystems (10) each have a storage battery (5) and a smart meter (6), each of which is linked to a microgrid monitoring and control system (2), which detects the amount of electric power consumed by the subsystems (10), and controls the transfer of electric power between the subsystems. |
| US08736092B2 |
Control system and a method for redundant control of a wind turbine
A control system and a method for controlling operation of a wind turbine are disclosed. A first sensor and a second sensor are arranged for sampling or continuously measuring a first physical value and a second physical value being representative of a first physical impact and a second physical impact on components of the wind turbine in order to provide a first and a second control parameter for controlling operation of the wind turbine. The first and second control parameters are distinct. During active generation of energy the control system is adapted to selectively switch between controlling the operation of the wind turbine either on the basis of the first control parameter or on the basis of the second control parameter, i.e. to selectively switch between two different, distinct and independent control strategies. The two control strategies allow redundancy in control of the operation of the wind turbine. Both control strategies are based on measurements of actual physical impacts affecting the components of the wind turbine, thereby making it possible to control the wind turbine in a more optimal manner than when using prior art control systems and methods, regardless of which control strategy is selected. |
| US08736089B2 |
Electric generator operated by random motion
It is disclosed a device which includes an elongated member, and an energy convertor. The elongated member has a base side and a free end. A certain direction is defined by a line connecting centers of the base side and the free end. The free end oscillates relative to the base side, in a response to a mechanical excitation, in a direction substantially perpendicular to the certain direction. The energy convertor converts mechanical energy of the oscillations of the free end to electrical energy. The energy convertor includes a coil attached to the free end, and a permanent magnet tightly fixed to the base side. Mechanical oscillation of the coil relative to the permanent magnet induces a flow of alternate current from the energy convertor. The energy convertor is electrically connected to a current rectifier for rectifying the alternate current, whereas the rectified direct current feeds a battery. The device is installed within a host mobile device, and the base side is fixed to the host mobile device. The device is enclosed within a vacuum chamber such as to prevent dissipation of energy of the mechanical oscillation by air friction. |
| US08736086B2 |
Reciprocal vibration type power generator equipped with inner columnar and outer annular magnetic members, a power storage device, a rectifying circuit, and a charging circuit
A reciprocal vibration type power generator includes a housing, a coil set seat, a power generation coil set surrounding the coil set seat, and a motion block including an outer magnetic member and a columnar magnet. An inner space is formed between the outer magnetic member and a periphery of the columnar magnet to enable reciprocal relative axial movement between the motion block and the coil set seat when the generator is vibrated. A rectifying and charging circuit is connected to the power generation coil set to rectify power induced in the power generation coil set upon movement of the motion block, and to supply the rectified power to a power storage device. The rectifying and charging circuit is also connected to input/output terminals on the generator housing for outputting power to an external device, and for inputting external charging power to the power storage device. |
| US08736085B2 |
Method and apparatus for direct energy conversion
A method and apparatus for direct energy conversion that combines the properties of Type II superconductor thin films, including the Meissner effect to create vortices to control and modulate static flux coupled in a magnetic circuit, where the laws of induction are used to produce an electrical signal without the use of moving armatures. The dynamics of magnetic flux modulation results from suppression of superconductivity and the Meissner effect by external photon irradiation. The apparatus employs a vortex channel based on the Meissner Effect, a laser, a permanent magnet, fiber optics for carrying the laser beam to the vortex channel, and a transformer composed of two separate windings. The transformer windings are arranged in a circuit having a first path through the permanent magnet and a first coil of the transformer windings; and a second path through the permanent magnet, the vortex channel, and the second coil of the transfer windings. |
| US08736077B2 |
Semiconductor package substrate
Disclosed herein is a semiconductor package substrate including a base substrate, a mounting member mounted on an upper portion of the base substrate, and an adhesive layer formed between the base substrate and the mounting member, wherein the adhesive layer includes a thermally conductive adhesive and a ductile adhesive formed at the outer circumference of the thermally conductive adhesive. |
| US08736074B2 |
Multi chip semiconductor device
According to an aspect of the invention, a semiconductor device includes a substrate having an opening area, a first semiconductor chip, and a second semiconductor chip. The first semiconductor chip has a first electrode for high-speed communication and that is disposed around the opening area on the substrate. The second semiconductor chip has a second electrode and third electrode for power and low-speed communication and that is disposed on the first semiconductor chip so that the first electrode is coupled with the second electrode by electrostatic coupling and dielectric coupling, the third electrode facing the opening area. |
| US08736073B2 |
Semiconductor device
A semiconductor device includes a first insulating layer; a wiring layer formed on a first surface of the first insulating layer and including a first electrode pad; a semiconductor chip; a second insulating layer including a semiconductor chip accommodating portion; a third insulating layer on the second insulating layer; and a passive element including an electrode and formed of an embedded portion and a protruding portion on a second surface of the first insulating layer, wherein an end surface of the embedded portion is coated by the insulating layer, the electrode of the passive element is electrically connected to the wiring layer through a via wiring formed in the insulating layers, the first electrode pad is electrically connected to another semiconductor device through a joining portion, and a protruding amount of the protruding portion is less than a gap between the second surface and the another semiconductor device. |
| US08736068B2 |
Hybrid bonding techniques for multi-layer semiconductor stacks
A circuit arrangement and method utilize hybrid bonding techniques that combine wafer-wafer bonding processes with chip-chip and/or chip-wafer bonding processes to form a multi-layer semiconductor stack, e.g., by bonding together one or more sub-assemblies formed by wafer-wafer bonding together with other sub-assemblies and/or chips using chip-chip and/or chip-wafer bonding processes. By doing so, the advantages of wafer-wafer bonding techniques, such as higher interconnect densities, may be leveraged with the advantages of chip-chip and chip-wafer bonding techniques, such as mixing and matching chips with different sizes, aspect ratios, and functions. |
| US08736067B2 |
Semiconductor device having a pad
A semiconductor device includes: a first insulating film formed on a substrate; a pad embedded in the first insulating film; and a second insulating film that is formed on the first insulating film and has an opening exposing at least part of the pad. The pad includes a plurality of pad interconnects, and an interconnect link is provided to electrically connect adjacent interconnects among the plurality of pad interconnects. The width of the pad interconnects is smaller than the height of the pad interconnects and larger than the width of the interconnect link. |
| US08736063B2 |
Semiconductor device and manufacturing method thereof
To provide a semiconductor device comprising a first layer that is provided on a semiconductor substrate and includes a first wiring pattern planarized by CMP and a plurality of first dummy patterns made of a same material as the first wiring pattern and a second layer that is provided above the semiconductor substrate and includes a second wiring pattern planarized by CMP and a plurality of second dummy patterns made of a same material as the second wiring pattern. A central axis of each of the second dummy patterns coincides with that of a corresponding one of the first dummy patterns in a direction perpendicular to the semiconductor substrate. |
| US08736061B2 |
Integrated circuits having a continuous active area and methods for fabricating same
Integrated circuits and methods for fabricating integrated circuits are provided. In an embodiment, an integrated circuit includes a standard cell having a first boundary, a second boundary opposite the first boundary, a third boundary interconnecting the first and second boundaries, and a fourth boundary opposite the third boundary and interconnecting the first and second boundaries. The standard cell further includes parallel active areas extending from the first boundary to the second boundary. Also, the standard cell has parallel gate strips extending from the third boundary to the fourth boundary and over the active areas. A cut mask overlies the gate strips. An interconnect is positioned overlying the cut mask and forms an electrical connection with a selected gate strip. |
| US08736060B2 |
Packaging structure
This invention relates to a packaging structure and method for manufacturing the packaging structure. The packaging structure comprises a substrate film, a plurality of chips, a compound resin layer and a support layer. The substrate film is formed with circuits having a plurality of terminals exposed from a solder mask. The chips, each of which has a plurality of pads, under bump metals (UBMs) formed on the pads, and composite bumps disposed onto the UBMs, are bonded onto the substrate film to form the first tape. The second tape comprises the support layer and the compound resin layer formed on the support layer. The first tape and the second tape are both in reel-form and are expanded towards a pair of rollers to be heated and pressurized for encapsulating the chips. |
| US08736046B2 |
Dual interlock heatsink assembly for enhanced cavity PBGA packages, and method of manufacture
A semiconductor package is provided, including a laminate substrate with an aperture sized to receive a semiconductor die. Through-holes in the substrate are filled with a thermally conductive adhesive. A first heat spreader is attached to the by the adhesive, and a semiconductor die is positioned in the aperture with a back face in thermal contact with the heat spreader. Wire bonds couple the die to electrical traces on the substrate. A second heat spreader is attached by the adhesive to the substrate over the die, directly opposite the first heat spreader. A portion of the second heat spreader is encapsulated in molding compound. Openings in the second heat spreader admits molding compound to fill the space around the die between the heat spreaders. Heat is transmitted from the die to the first spreader, and thence, via the through-holes and conductive paste, to the second heat spreader. |
| US08736044B2 |
Lid for an electrical hardware component
To minimize the warpage of an organic substrate that supports at least one electrical hardware component (e.g., a system-in-package module), a bottom surface of a lid is attached to a top surface of the electrical hardware component. The lid includes a leg that extends from the bottom surface of the lid towards a top surface of the substrate. A portion of the leg closest to the substrate may move relative to the substrate. As the lid warps, the lid does not also cause distortion of the substrate. The leg may be a flange that extends at least a portion of the width or at least a portion of the length of the lid, may be a post located at the perimeter of the lid, or may be any other portion extending from above the electrical component towards the substrate. |
| US08736043B2 |
Power device having a specific range of distances between collector and emitter electrodes
A power semiconductor device is provided in which reliability can be improved when the parallel number of semiconductor devices increases. When a bonding face on collector electrode is on an upper side, and a bonding face on emitter electrode is on a lower side, a collector electrode joint region as a joint region between a collector trace and a collector electrode on a chip mounted substrate and an emitter electrode joint region as a joint region between an emitter trace and an emitter electrode are located at a same position in an up-and-down direction and are adjacent in a right-and-left direction at an interval of 2 mm or more and 4 mm or less. |
| US08736042B2 |
Delamination resistant device package having raised bond surface and mold locking aperture
A semiconductor package configured to attain a thin profile and low moisture sensitivity. Packages of this invention can include a semiconductor die mounted on a die attachment site of a leadframe and further connected with a plurality of elongate I/O leads arranged about the die attach pad and extending in said first direction. The leadframe having an “up-set” bonding pad arranged with a bonding support for supporting a plurality of wire bonds and a large mold flow aperture in the up-set bonding pad. The package encapsulated in a mold material that surrounds the bonding support and flows through the large mold flow aperture to establish well supported wire bonds such that the package has low moisture sensitivity. |
| US08736038B2 |
Lead frame having increased stability due to reinforced die pads and packaging method using such lead frame
There is provided a lead frame and a packaging method. The lead frame comprises a first plurality of die pads, a second plurality of leads extending from the first plurality of die pads, and a third plurality of tie elements, each of which connects one of the first plurality of die pads to another. |
| US08736028B2 |
Semiconductor device structures and printed circuit boards comprising semiconductor devices
The present invention relates to methods for forming through-wafer interconnects in semiconductor substrates and the resulting structures. In one embodiment, a method for forming a through-wafer interconnect includes providing a substrate having a pad on a surface thereof, depositing a passivation layer over the pad and the surface of the substrate, and forming an aperture through the passivation layer and the pad using a substantially continuous process. An insulative layer is deposited in the aperture followed by a conductive layer and a conductive fill. In another embodiment of the invention, a semiconductor device is formed including a first interconnect structure that extends through a conductive pad and is electrically coupled with the conductive pad while a second interconnect structure is formed through another conductive pad while being electrically isolated therefrom. Semiconductor devices and assemblies produced with the methods are also disclosed. |
| US08736027B2 |
Semiconductor device, fabrication process, and electronic device
A semiconductor device includes: a semiconductor substrate that includes a semiconductor; an electrode layer formed on a first surface side inside the semiconductor substrate; a frame layer laminated on the first surface of the semiconductor substrate; a conductor layer formed in an aperture portion formed by processing the semiconductor substrate and the frame layer in such a manner as to expose the electrode layer on the first surface of the semiconductor substrate; a vertical hole formed through the semiconductor substrate from a second surface of the semiconductor substrate to the conductor layer; and a wiring layer that is electrically connected to the electrode layer via the conductor layer at an end portion of the vertical hole, and that extends to the second surface of the semiconductor substrate. |
| US08736024B2 |
Semiconductive ceramic sintered compact
There is provided a semiconductive ceramic sintered compact that has a conductivity high enough to attain static electricity removal and antistatic purposes and, at the same time, has excellent mechanical properties or stability over time. The semiconductive ceramic sintered compact includes a main phase and a conductive phase, wherein the main phase is a ceramic sintered phase including Al2O3 particles, the area ratio of the conductive phase to the main phase is 0% (exclusive) to 10% (inclusive), and the conductive phase includes two or more metals selected from Mn (manganese), Fe (iron), and Ti (titanium) and has a composition meeting a relation of Mn/(Ti+Mn+Fe)>0.08 or Mn/Ti>0.15. |
| US08736015B2 |
Integrated circuit structure and method of forming the same
An embodiment is an integrated circuit (IC) structure. The structure comprises a deep n well in a substrate, a first pickup device in the deep n well, a first signal device in the deep n well, a dissipation device in the substrate, a second signal device in the substrate, a first electrical path between the first pickup device and the dissipation device, and a second electrical path between the first signal device and the second signal device. The dissipation device is outside of the deep n well, and the second signal device is outside of the deep n well. A highest point of the first electrical path is lower than a highest point of the second electrical path. |
| US08736012B2 |
Trenched semiconductor structure
A trenched semiconductor structure comprises a semiconductor substrate, an epitaxial layer, an ion implantation layer, a termination region dielectric layer, an active region dielectric layer, and a first polysilicon layer. The epitaxial layer doped with impurities of a first conductive type is formed on the semiconductor substrate. A plurality of active region trenches and a termination region trench are formed in the epitaxial layer. The ion implantation layer is formed in the active region trenches by doping impurities of a second conductive type. The termination region dielectric layer covers the termination region trench. The active region dielectric layer covers the ion implantation region. The first polysilicon layer covers the active region dielectric layer and fills the active region trenches. The depth of the termination region trench is greater than that of the active region trenches and close to that of the depletion region under reverse breakdown. |
| US08736011B2 |
Low thermal conductivity matrices with embedded nanostructures and methods thereof
A matrix with at least one embedded array of nanowires and method thereof. The matrix includes nanowires and one or more fill materials located between the nanowires. Each of the nanowires including a first end and a second end. The nanowires are substantially parallel to each other and are fixed in position relative to each other by the one or more fill materials. Each of the one or more fill materials is associated with a thermal conductivity less than 50 Watts per meter per degree Kelvin. And, the matrix is associated with at least a sublimation temperature and a melting temperature, the sublimation temperature and the melting temperature each being above 350° C. |
| US08736010B2 |
Pyroelectric detector, pyroelectric detection device, and electronic instrument
A pyroelectric detector includes a pyroelectric detection element, a support member, and a support part. The pyroelectric detection element has a capacitor including a first electrode, a second electrode, and a pyroelectric body disposed between the first and second electrodes, and a first reducing gas barrier layer that protects the capacitor from reducing gas. The support member includes first and second sides with the pyroelectric detection element being mounted on the first side and the second side facing a cavity. The support member has a mounting member on which the capacitor is mounted and an arm member linked to the mounting member. The support part supports a portion of the support member. An outer peripheral edge of the first reducing gas barrier layer is disposed between and spaced apart from an outer peripheral edge of the mounting member and an outer peripheral edge of the capacitor in plan view. |
| US08736008B2 |
Photodiode array and methods of fabrication
Photodiode arrays and methods of fabrication are provided. One photodiode array includes a silicon wafer having a first surface and an opposite second surface and a plurality of conductive vias through the silicon wafer. The photodiode array further includes a patterned doped epitaxial layer on the first surface, wherein the patterned doped epitaxial layer and the substrate form a plurality of diode junctions. A patterned etching defines an array of the diode junctions. |
| US08736004B2 |
Magnetic tunnel junction for MRAM applications
Reading margin is improved in a MTJ designed for MRAM applications by employing a pinned layer with an AP2/Ru/AP1 configuration wherein the AP1 layer is a CoFeB/CoFe composite and by forming a MgO tunnel barrier adjacent to the CoFe AP1 layer by a sequence that involves depositing and oxidizing a first Mg layer with a radical oxidation (ROX) process, depositing and oxidizing a second Mg layer with a ROX method, and depositing a third Mg layer on the oxidized second Mg layer. The third Mg layer becomes oxidized during a subsequent anneal. MTJ performance may be further improved by selecting a composite free layer having a Fe/NiFeHf or CoFe/Fe/NiFeHf configuration where the NiFeHf layer adjoins a capping layer in a bottom spin valve configuration. As a result, read margin is optimized simultaneously with improved MR ratio, a reduction in bit line switching current, and a lower number of shorted bits. |
| US08736003B2 |
Integrated hybrid hall effect transducer
A Hall effect transducer in a semiconductor wafer comprises a first layer of semiconducting material, a second layer of semiconducting material, and a contact structure configured to provide a path for electrical current to pass through the second layer. The second layer has higher electron hole mobility than the first layer, and is epitaxially grown atop the first layer. |
| US08736000B1 |
Capacitive chemical sensor
A microfabricated capacitive chemical sensor can be used as an autonomous chemical sensor or as an analyte-sensitive chemical preconcentrator in a larger microanalytical system. The capacitive chemical sensor detects changes in sensing film dielectric properties, such as the dielectric constant, conductivity, or dimensionality. These changes result from the interaction of a target analyte with the sensing film. This capability provides a low-power, self-heating chemical sensor suitable for remote and unattended sensing applications. The capacitive chemical sensor also enables a smart, analyte-sensitive chemical preconcentrator. After sorption of the sample by the sensing film, the film can be rapidly heated to release the sample for further analysis. Therefore, the capacitive chemical sensor can optimize the sample collection time prior to release to enable the rapid and accurate analysis of analytes by a microanalytical system. |
| US08735997B2 |
Semiconductor device having drain/source surrounded by impurity layer and manufacturing method thereof
A transistor structure that improves ESD withstand voltages is offered. A high impurity concentration drain layer is formed in a surface of an intermediate impurity concentration drain layer at a location separated from a drain-side end of a gate electrode. And a P-type impurity layer is formed in a surface of a substrate between the gate electrode and the high impurity concentration drain layer so as to surround the high impurity concentration drain layer. When a parasitic bipolar transistor is turned on by an abnormal surge, electrons travel from a source electrode to a drain electrode. Here, electrons travel dispersed in the manner to avoid a vicinity X of the surface of the substrate and travel through a deeper path to the drain electrode as indicated by arrows in FIG. 4. |
| US08735996B2 |
Scavenging metal stack for a high-K gate dielectric
A semiconductor structure is provided. The structure includes a semiconductor substrate of a semiconductor material and a gate dielectric having a high dielectric constant dielectric layer with a dielectric constant greater than silicon. The gate dielectric is located on the semiconductor substrate. A gate electrode abuts the gate dielectric. The gate electrodes includes a lower metal layer abutting the gate dielectric, a scavenging metal layer abutting the lower metal layer, an upper metal layer abutting the scavenging metal layer, and a silicon layer abutting the upper metal layer. The scavenging metal layer reduces an oxidized layer at an interface between the upper metal layer and the silicon layer responsive to annealing. |
| US08735992B2 |
Power switch with active snubber
A power switch with active snubber. In accordance with a first embodiment, an electronic circuit includes a first power semiconductor device and a second power semiconductor device coupled to the first power semiconductor device. The second power semiconductor device is configured to oppose ringing of the first power semiconductor device. |
| US08735990B2 |
Radiation hardened FinFET
The embodiments of the invention provide a structure and method for a rad-hard FinFET or mesa. More specifically, a semiconductor structure is provided having at least one fin or mesa comprising a channel region on an isolation region. A doped substrate region is also provided below the fin, wherein the doped substrate region has a first polarity opposite a second polarity of the channel region. The isolation region contacts the doped substrate region. The structure further includes a gate electrode covering the channel region and at least a portion of the isolation region. The gate electrode comprises a lower portion below the channel region of the fin, wherein the lower portion of the gate electrode comprises a height that is at least one-half of a thickness of the fin. |
| US08735988B2 |
Semiconductor device having a first spacer element and an adjacent second spacer element
The present disclosure describes a semiconductor device including a semiconductor substrate and a gate stack disposed on the semiconductor substrate. A first spacer element is disposed on the substrate abutting the first gate stack. In an embodiment, the first spacer element includes silicon nitride. A second spacer element is adjacent the first spacer element. In an embodiment, the second spacer element includes silicon oxide. A raised source and a first raised drain is provided laterally contacting sidewalls of the second spacer element. In an embodiment, a contact directly interfaces with the second spacer element. |
| US08735983B2 |
Integrated circuit transistors with multipart gate conductors
Metal-oxide-semiconductor transistors are provided. A metal-oxide-semiconductor transistor may be formed on a semiconductor substrate. Source and drain regions may be formed in the substrate. A gate insulator such as a high-K dielectric may be formed between the source and drain regions. A gate may be formed from multiple gate conductors. The gate conductors may be metals with different workfunctions. A first of the gate conductors may form a pair of edge gate conductors that are adjacent to dielectric spacers. An opening between the edge gate conductors may be filled with the second gate conductor to form a center gate conductor. A self-aligned gate formation process may be used in fabricating the metal-oxide-semiconductor transistor. |
| US08735982B2 |
Semiconductor device with superjunction structure
A superjunction semiconductor device is disclosed which has, in the active section, a first alternating-conductivity-type layer which makes a current flow in the ON-state of the device and sustains a bias voltage in the OFF-state of the device. There is a second alternating-conductivity-type layer in a edge-termination section surrounding the active section. The width of a region of a second conductivity type in the second alternating-conductivity-type layer becomes narrower at a predetermined rate from the edge on the active section side toward the edge of the edge termination section. The superjunction semiconductor device facilitates manufacturing the edge-termination section which exhibits a high breakdown voltage and a high reliability for breakdown voltage through a process that exhibits a high mass-productivity. |
| US08735979B2 |
Multi-channel homogenous path for enhanced mutual triggering of electrostatic discharge fingers
Mutual triggering of electrostatic discharge (ESD) fingers is improved by creating a base contact in each individual finger and connecting all of these base contacts in parallel. The local base contact in each ESD finger is located at a position where the base voltage significantly increases when the ESD current increases. Thus when an ESD finger is triggered its local base voltage will tend to significantly increase. Since all of the ESD finger bases are connected in parallel this local voltage increase will forward bias the base-emitter junctions of the other ESD fingers, thus triggering them all. By sharing the triggering current from the fastest ESD finger with the slower ones ensures that all ESD fingers are triggered during an ESD event. |
| US08735971B2 |
Method for producing semiconductor device and semiconductor device
A SGT production method includes a step of forming first and second fin-shaped silicon layers, forming a first insulating film, and forming first and second pillar-shaped silicon layers; a step of forming diffusion layers by implanting an impurity into upper portions of the first and second pillar-shaped silicon layers, upper portions of the first and second fin-shaped silicon layers, and lower portions of the first and second pillar-shaped silicon layers; a step of forming a gate insulating film and first and second polysilicon gate electrodes; a step of forming a silicide in upper portions of the diffusion layers formed in the upper portions of the first and second fin-shaped silicon layers; and a step of depositing an interlayer insulating film, exposing and etching the first and second polysilicon gate electrodes, then depositing a metal, and forming first and second metal gate electrodes. |
| US08735969B1 |
Semiconductor structure and manufacturing method of the same
A semiconductor structure and a manufacturing method thereof are provided. The semiconductor structure includes a stacked structure, a plurality of first conductive blocks, a plurality of first conductive layers, a plurality of second conductive layers, and a plurality of conductive damascene structures. The stacked structure, comprising a plurality of conductive strips and a plurality of insulating strips, is formed on a substrate, and the conductive strips and the insulating strips are interlaced. The first conductive blocks are formed on the stacked structure. The first conductive layers and the second conductive layers are formed on two sidewalls of the stacked structure, respectively. The conductive damascene structures are formed on two sides of the stacked structure, wherein each of the first conductive blocks is electrically connected to each of the conductive damascene structures via each of the first conductive strips and each of the second conductive strips. |
| US08735968B2 |
Integrated MOSFET devices with Schottky diodes and associated methods of manufacturing
The present technology discloses a semiconductor die integrating a MOSFET device and a Schottky diode. The semiconductor die comprises a MOSFET area comprising the active region of MOSFET, a Schottky diode area comprising the active region of Schottky diode, and a termination area comprising termination structures. Wherein the Schottky diode area is placed between the MOSFET area and the termination area such that the Schottky diode area surrounds the MOSFET area. |
| US08735967B2 |
Semiconductor memory device and method of manufacturing the same
A semiconductor memory device includes a lower select transistor formed within a semiconductor substrate, memory cells stacked over the lower select transistors, and an upper select transistor formed over the memory cells. |
| US08735964B2 |
Charge carrier device
An apparatus is provided which includes an array of impurity ions disposed in an insulating region, a semiconductor region adjacent to the insulating region, an array of electrometers arranged to detect charge carriers in the semiconductor region and an array of sets of at least one control gate configured to apply an electric field to the insulating region and semiconductor region. Each control gate is operable to cause at least one charge carrier in the semiconducting material region to bind to the impurity ion without the at least one charge carrier leaving the semiconductor material region. The electrometers are operable to detect whether the at least one charge carrier is bound to the impurity ion. |
| US08735960B2 |
High ultraviolet light absorbance silicon oxynitride film for improved flash memory device performance
An ultraviolet light absorbent silicon oxynitride layer overlies a memory cell including a pair of source/drains, a gate insulator, a floating gate, a dielectric layer, and a control gate. A conductor is disposed through the silicon oxynitride layer for electrical connection to the control gate, and another conductor is disposed through the silicon oxynitride layer for electrical connection to a source/drain. |
| US08735958B1 |
Multi-layer polysilicon suppression of implant species penetration
A blocking semiconductor layer minimizes penetration of implant species into a semiconductor layer beneath the blocking semiconductor layer. The blocking semiconductor layer may have grains with relatively fine or small grain sizes and/or may have a dopant in a relatively low concentration to minimize penetration of implant species into the semiconductor layer beneath the blocking semiconductor layer. |
| US08735957B2 |
Vertical MOSFET transistor with a vertical capacitor region
Consistent with an example embodiment, there is a package that includes a first voltage terminal, and a second voltage terminal, a first die including a first MOSFET having a drain region electrically connected to the first voltage terminal and further having a source region, A second die is adjacent to the first die, the second die includes a second MOSFET having a drain region electrically connected to the source region of the first MOSFET and having a source region electrically connected to the second voltage terminal. The semiconductor package further includes a vertical capacitor having a first plate electrically connected to the drain region of the first MOSFET and a second plate electrically connected to the source region of the second MOSFET and the second plate is electrically insulated from the first plate by a dielectric material. The capacitor is integrated on the first die or the second die. |
| US08735956B2 |
Semiconductor device and method for manufacturing the same
A semiconductor device and a method for manufacturing the same are disclosed. An additional spacer is formed at a lateral surface of an upper part of the bit line so that the distance of insulation films between a storage node and a neighboring storage node contact plug is increased. Accordingly, the distance between the storage node and the neighboring storage node contact is guaranteed and a bridge failure is prevented. |
| US08735951B2 |
Semiconductor device having diffusion barrier element injection region
A semiconductor device includes an isolation pattern disposed on a substrate, the isolation pattern defining an active part, a gate pattern crossing the active part on the substrate, the gate pattern including a dielectric pattern and a first conductive pattern, and the dielectric pattern being between the active part and the first conductive pattern, a pair of doping regions in the active part adjacent to side walls of the gate pattern, the gate pattern being between the pair of doping regions, and a diffusion barrier element injection region disposed in an upper region of the active part. |
| US08735948B2 |
Semiconductor device
A semiconductor device according to the present invention includes: a semiconductor substrate; a source region formed in a top layer portion of the semiconductor substrate; a drain region formed in the top layer portion of the semiconductor substrate and spaced apart from the source region; a gate electrode formed on the semiconductor substrate and opposing to an interval between the source region and the drain region; a wiring formed on the semiconductor substrate and connected to the source region, the drain region, or the gate electrode; and a MEMS sensor disposed on the semiconductor substrate. The MEMS sensor includes: a thin film first electrode made of the same material as the gate electrode and formed in the same layer as the gate electrode; and a second electrode made of the same material as the wiring, formed in the same layer as the wiring, and spaced apart from the first electrode at a side opposite to the semiconductor substrate side of the first electrode. |
| US08735939B2 |
Solid state imaging device
According to one embodiment, a solid state imaging device includes a photoelectric converting portion including a semiconductor region and a semiconductor film. The semiconductor region has a first region and a second region. The first region is of a second conductivity type. The first region is provided in a semiconductor substrate. The second region is of a first conductivity type. The first conductivity type is a different conductivity type from the second conductivity type. The second region is provided on the first region. The semiconductor film is of the second conductivity type. The semiconductor film is provided on the semiconductor region. An absorption coefficient of a material of the semiconductor film to a visible light is higher than an absorption coefficient of a material of the semiconductor substrate to the visible light. A thickness of the semiconductor film is smaller than a thickness of the semiconductor region. |
| US08735935B2 |
Small size light emitting device and manufacturing method of the same
There is provided a light emitting device including: a package body having first and second circumferential surfaces and a plurality of side surfaces formed therebetween, the package body defined into first and second level areas including the first and second circumferential surfaces, respectively; first and second external terminal blocks each having an electrical contact part; an LED chip disposed between the first and second external terminal blocks in the first level area and having an electrode surface where first and second electrodes are formed; and wires electrically connected to first and second electrodes of the LED chip to the electrical contact parts of the first and second external terminal blocks, respectively. |
| US08735930B2 |
Optoelectronic component with multi-part housing body
An optoelectronic component (1) is proposed that comprises a housing body (2) and at least one semiconductor chip (8) disposed thereon, said housing body having a base part (13) comprising a connector body (16), on which a connecting conductor material (6, 7) is disposed, and said housing body having a reflector part (14) comprising a reflector body (23), on which a reflector material (9) is disposed, wherein said connector body and said reflector body are preformed separately from each other and said reflector body is disposed on said connector body in the form of a reflector top. |
| US08735929B2 |
Light-emitting diode package
A light-emitting diode (LED) package comprising a carrier, an LED chip and a phosphor glue is provided. The carrier has a recess, an upper surface, and a ring-shape rough surface connected to a top edge of the recess. The LED chip is disposed within the recess. The phosphor glue fills up the recess and over the upper surface of the carrier. An edge of the phosphor glue contacts the ring-shape rough surface. |
| US08735927B2 |
Group III nitride semiconductor light-emitting device
The invention provides a Group III nitride semiconductor light-emitting device which has a light extraction face at the n-layer side and which provides high light emission efficiency. The light-emitting device is produced through the laser lift-off technique. The surface of the n-GaN layer of the light-emitting device is roughened. On the n-GaN layer, a transparent film is formed. The transparent film satisfies the following relationship: 0.28≦n×d1×2/λ≦0.42 or 0.63≦n×d1×2/λ≦0.77, wherein n represents the refractive index of the transparent film, d1 represents the thickness of the transparent film in the direction orthogonal to an inclined face thereof, and λ represents the wavelength of the light emitted from the MQW layer. |
| US08735925B2 |
Semiconductor light emitting device and method for manufacturing the same
Certain embodiments provide a semiconductor light emitting device including: a first metal layer; a stack film including a p-type nitride semiconductor layer, an active layer, and an n-type nitride semiconductor layer; an n-electrode; a second metal layer; and a protection film protecting an outer circumferential region of the upper face of the n-type nitride semiconductor layer, side faces of the stack film, a region of an upper face of the second metal layer other than a region in contact with the p-type nitride semiconductor layer, and a region of an upper face of the first metal layer other than a region in contact with the second metal layer. Concavities and convexities are formed in a region of the upper face of the n-type nitride semiconductor layer, the region being outside the region in which the n-electrode is provided and being outside the regions covered with the protection film. |
| US08735924B2 |
Group III nitride semiconductor light-emitting device
A Group III nitride semiconductor light-emitting device having an Ag or Ag alloy reflective film provided in an insulating film, at least a portion of the reflective film is located via the insulating film in a region between an n-lead electrode and at least one of a p-contact electrode having transparency and a p-type layer, wherein a conductive film is formed via the insulating film between the n-lead electrode and the reflective film of the region, and the conductive film is electrically connected to at least one of the p-contact electrode and the p-type layer. |
| US08735923B2 |
Semiconductor light emitting device and manufacturing method thereof
There is provided a semiconductor light emitting device and method of making the same, having a first conductivity type semiconductor layer; an active layer formed on the first conductivity type semiconductor layer; a second conductivity type semiconductor layer formed on the active layer and including a plurality of holes; and a transparent electrode formed on the second conductivity type semiconductor layer. |
| US08735920B2 |
Light emitting diode package with optical element
A light emitting diode (LED) package comprising a substrate with an LED chip mounted to the substrate and in electrical contact with it. An inner material covers the LED chip, and a lens covers the inner material with the lens material being harder than the inner material. An adhesive is arranged between the substrate and the lens to hold the lens to the substrate and to compensate for different coefficients of thermal expansion (CTE) between the lens and the remainder of the package. A method for forming an LED package comprises providing a substrate with a first meniscus ring on a surface of the substrate. An LED chip is mounted to the substrate, within the meniscus ring. An inner material is deposited over the LED chip, and a lens material in liquid form is deposited over the inner material. The lens material held in a hemispheric shape by the first meniscus feature and the lens material is cured making it harder than the inner material. |
| US08735914B2 |
Light emitting device having plural light-emitting sections with resin walls within resin frame
A light emitting device is a light emitting device using light emitting elements and includes: a substrate; a resin frame provided circularly on the substrate; a resin wall provided on the substrate so as to partition an area surrounded by the resin frame into 2 zones; light-emitting sections (a first light-emitting section: blue LEDs+red fluorescent material, a second light-emitting section: blue LEDs+yellow fluorescent material) provided in the respective zones, each of which light-emitting sections includes at least one light emitting element; and first and second anode electrodes and a cathode electrode provided so that each of the light-emitting sections receives current via a corresponding anode electrode and the cathode electrode, the light-emitting sections emitting respective pieces of light each having at least one color, which respective pieces of light have different colors from each other, the first and second anode electrodes being electrically connected to the first and second light-emitting sections, respectively. With the arrangement, which can increase an integration degree, it is possible to achieve a high color rendering property and an excellent color mixing property, to easily adjust a chromaticity, and to easily generate light with a desired chromaticity. |
| US08735910B2 |
Light-emitting device
Provided are a light-emitting device, a light-emitting device package, and a method for fabricating the light-emitting device. The light-emitting device includes a first light-emitting structure; an insulation layer having non-conductivity, in which a current does not flow, on the first light-emitting structure; a second light-emitting structure on the insulation layer; and a common electrode simultaneously and electrically connected to the first light-emitting structure and the second light-emitting structure. |
| US08735907B2 |
Ohmic electrode for use in a semiconductor diamond device
In a semiconductor diamond device, there is provided an ohmic electrode that is chemically and thermally stable and has an excellent low contact resistance and high heat resistance. A nickel-chromium alloy, or a nickel-chromium compound, containing Ni and Cr such as Ni6Cr2 or Ni72Cr18Si10, which is chemically and thermally stable, is formed on a semiconductor diamond by a sputtering process and so forth, to thereby obtain the semiconductor diamond device provided with an excellent ohmic electrode. If heat treatment is applied after forming the nickel-chromium alloy or compound, it is improved in characteristics. |
| US08735903B2 |
Density of states engineered field effect transistor
Layer structures for use in density of states (“DOS”) engineered FETs are described. One embodiment comprises a layer structure for use in fabricating an n-channel transistor. The layer structure includes a first semiconductor layer having a conduction band minimum EC1; a second semiconductor layer having a discrete hole level H0; a wide bandgap semiconductor barrier layer disposed between the first and the second semiconductor layers; a gate dielectric layer disposed above the first semiconductor layer; and a gate metal layer disposed above the gate dielectric layer; wherein the discrete hole level H0 is positioned below the conduction band minimum Ec1 for zero bias applied to the gate metal layer. |
| US08735896B2 |
Light-emitting device
According to present invention, system on panel without complicating the process of TFT can be realized, and a light-emitting device that can be formed by lower cost than that of the conventional light-emitting device can be provided. A light-emitting device is provided in which a pixel portion is provided with a pixel including a light-emitting element and a TFT for controlling supply of current to the light-emitting element; a TFT included in a drive circuit and a TFT for controlling supply of current to the light-emitting element include a gate electrode, a gate insulating film formed over the gate electrode, a first semiconductor film, which overlaps with the gate electrode via the gate insulating film, a pair of second semiconductor films formed over the first semiconductor film; the pair of second semiconductor films are doped with an impurity to have one conductivity type; and the first semiconductor film is formed by semiamorphous semiconductor. |
| US08735893B2 |
Visible sensing transistor, display panel and manufacturing method thereof
A display device includes an infrared sensing transistor and a visible sensing transistor. The visible sensing transistor includes a semiconductor on a substrate; an ohmic contact on the semiconductor; an etch stopping layer on the ohmic contact; a source electrode and a drain electrode on the etch stopping layer; a passivation layer on the source electrode and the drain electrode; and a gate electrode on the passivation layer. The etch stopping layer may be composed of the same material as the source electrode and the drain electrode. The infrared sensing transistor is similar to the visible sensing transistor except the etch stopping layer is absent. |
| US08735888B2 |
TFT-LCD array substrate and manufacturing method thereof
An embodiment of the invention relates to a TFT-LCD array substrate comprising a substrate, a gate line and a data line formed on the substrate, a pixel electrode and a thin film transistor formed in a pixel region defined by the gate line and the data line, wherein the thin film transistor comprises a gate electrode, a source electrode, and a transparent drain electrode, and the transparent drain electrode is electrically connected with the pixel electrode. |
| US08735884B2 |
Semiconductor device including oxide semiconductor
An object is to provide a display device which operates stably with use of a transistor having stable electric characteristics. In manufacture of a display device using transistors in which an oxide semiconductor layer is used for a channel formation region, a gate electrode is further provided over at least a transistor which is applied to a driver circuit. In manufacture of a transistor in which an oxide semiconductor layer is used for a channel formation region, the oxide semiconductor layer is subjected to heat treatment so as to be dehydrated or dehydrogenated; thus, impurities such as moisture existing in an interface between the oxide semiconductor layer and the gate insulating layer provided below and in contact with the oxide semiconductor layer and an interface between the oxide semiconductor layer and a protective insulating layer provided on and in contact with the oxide semiconductor layer can be reduced. |
| US08735880B2 |
Light emitting transistor
A static induction light emitting transistor comprising: on a substrate: a source electrode; a hole transporting layer in which a slit-shaped gate electrode is embedded; an equipotential layer; light emitting layer; and a transparent or semitransparent drain electrode, provided in this order. In this light emitting transistor, the drain electrode provided on the opposite side of the gate electrode, viewing from the light emitting layer, is transparent or semitransparent. |
| US08735878B2 |
Charge transporting material and organic electroluminescence device
In order to provide an organic electroluminescence device with high luminous efficiency and good durability, the present invention provides a charge transporting material including a compound represented by Formula (Cz-1) wherein the content of a particular halogen-containing impurity in the charge transporting material is from 0.000% to 0.10% when the content is calculated as a proportion of the absorption intensity area of the impurity with respect to the total absorption intensity area of the charge transporting material, as measured by high-performance liquid chromatography at a measurement wavelength of 254 nm, and an organic electroluminescence device wherein the charge transporting material is included in an organic layer: wherein in Formula (Cz-1), each of R1 to R5 independently represents a particular atom or group; and each of n1 to n5 independently represents a particular integer. |
| US08735874B2 |
Light-emitting device, display device, and method for manufacturing the same
It is known that a light-emitting element utilizing organic EL deteriorates due to moisture. Therefore, a sealing technique to prevent moisture permeation is important. A light-emitting device including a light-emitting element utilizing organic EL is manufactured over a support substrate having flexibility and a high heat dissipation property (e.g., stainless steel or duralumin), and the light-emitting device is sealed with a stack body having moisture impermeability and a high light-transmitting property or with glass having moisture impermeability and a high light-transmitting property and having a thickness greater than or equal to 20 μm and less than or equal to 100 μm. |
| US08735871B2 |
Organic thin film transistors
An organic thin film transistor comprising: a substrate; a source electrode and a drain electrode disposed over the substrate with a channel region therebetween; a layer of organic semiconductor disposed in the channel region; a gate electrode; and a gate dielectric disposed between the layer of organic semiconductor and the gate electrode, wherein the gate dielectric comprises a cross-linked polymer and a fluorine containing polymer. |
| US08735865B2 |
Semiconductor memory device
For decreasing a recording current and suppressing a cross erase simultaneously, a three-dimensional phase-change memory for attaining higher sensitivity and higher reliability by the provision of a chalcogenide type interface layer is provided, in which an electric resistivity, a thermal conductivity, and a melting point of the material of the interface layer are selected appropriately, thereby improving the current concentration to the phase-change material and thermal and material insulation property with Si channel upon writing. |
| US08735864B2 |
Nonvolatile memory device using a tunnel nitride as a current limiter element
Embodiments of the invention generally include a method of forming a nonvolatile memory device that contains a resistive switching memory element that has an improved device switching performance and lifetime, due to the addition of a current limiting component disposed therein. In one embodiment, the current limiting component comprises a resistive material that is configured to improve the switching performance and lifetime of the resistive switching memory element. The electrical properties of the current limiting layer are configured to lower the current flow through the variable resistance layer during the logic state programming steps (i.e., “set” and “reset” steps) by adding a fixed series resistance in the resistive switching memory element found in the nonvolatile memory device. In one embodiment, the current limiting component comprises a tunnel nitride that is a current limiting material that is disposed within a resistive switching memory element in a nonvolatile resistive switching memory device. |
| US08735862B2 |
Memory cells, methods of forming memory cells and methods of forming memory arrays
Some embodiments include memory cells which have multiple programmable material structures between a pair of electrodes. One of the programmable material structures has a first edge, and another of the programmable material structures has a second edge that contacts the first edge. Some embodiments include methods of forming an array of memory cells. First programmable material segments are formed over bottom electrodes. The first programmable material segments extend along a first axis. Lines of second programmable material are formed over the first programmable material segments, and are formed to extend along a second axis that intersects the first axis. The second programmable material lines have lower surfaces that contact upper surfaces of the first programmable material segments. Top electrode lines are formed over the second programmable material lines. |
| US08735859B2 |
Nonvolatile semiconductor memory device
A nonvolatile semiconductor memory device includes: a first interconnect; a second interconnect at a position opposing the first interconnect; and a variable resistance layer between the first interconnect and the second interconnect, the variable resistance layer being capable of reversibly changing between a first state and a second state by a voltage applied via the first interconnect and the second interconnect or a current supplied via the first interconnect and the second interconnect, the first state having a first resistivity, the second state having a second resistivity higher than the first resistivity. Wherein the variable resistance layer has a compound of carbon and silicon as a main component and including hydrogen. |
| US08735858B2 |
Ionic devices with interacting species
An ionic device includes a layer of an ionic conductor containing first and second species of impurities. The first species of impurity in the layer is mobile in the ionic conductor, and a concentration profile of the first species determines a functional characteristic of the device. The second species of impurity in the layer interacts with the first species within the layer to create a structure that limits mobility of the first species in the layer. |
| US08735856B2 |
Fiber optic liquid level detector
The present invention provides a hollow prism for detecting liquid level in the presence of an optical beam, including a hollow member, dielectric members sealed to the hollow member with one of the dielectric members arranged at an inclined angle to the other, a sealed hollow space disposed between said dielectric members, wherein an incident optical beam enters through the first dielectric member at normal incidence and exits as an emergent beam through the second dielectric member, and wherein the emergent optical beam remains undeviated when the hollow member not immersed in a liquid medium and the emergent beam suffers deviation when immersed in the liquid medium. The present invention also provides a fiber optic liquid level detector with the hollow prism for detecting liquid levels. |
| US08735854B2 |
Scintillator panel
A scintillator panel exhibiting enhanced moisture resistance is disclosed, comprising a scintillator sheet provided on a substrate with a scintillator layer, and the whole of the scintillator sheet is covered with a protective layer and a space in which gas is capable of flowing is provided between the protective layer and the scintillator sheet. |
| US08735853B2 |
Fluorescence flow cytometry
A flow cytometer including a laser, indexing structure, adjustment structure, and sensor structure. The cytometer is conventionally used with a removable microfluidic cassette, which is installed at a first position that is enforced by the indexing structure. The adjustment structure changes a relative position between an interrogation aperture of the cassette and the laser beam. Feedback from the sensor structure is used to optimize propagation of the laser through the interrogation aperture to reduce (and hopefully eliminate) autofluorescence caused by beam impingement onto the cassette. |
| US08735852B2 |
Matrix-incorporated fluorescent silica for anti-counterfeiting
The present invention relates to a fluorescent dye-incorporated silica material. A fluorescent dye is covalently bonded to a silica matrix. The invention also provides for a method for verifying the authenticity of a product, wherein the fluorescent silica material is present in or on a product, and the material is tested for fluorescence or structure. |
| US08735851B2 |
Device and method for quantifying a surface's cleanliness
Provided are devices and methods for quantifying a surface's cleanliness relative to a contaminant. Such devices and methods may comprise and/or use a source of interrogating radiation to which the contaminant is responsive, a means for directing the interrogating radiation, a detector, and an analyzer. Radiation emitted from the source is directed by the radiation means toward an article having the surface or comprising a surface cleaner that may hold the contaminant. The detector detects radiation from the article produced in response to the interrogating radiation by the contaminant, e.g., fluorescent or phosphorescent radiation, and generate a corresponding signal that is compared by the analyzer relative to an electronic standard that corresponds to the surface in an acceptably clean state so as to quantify the surface's cleanliness. |
| US08735847B2 |
High resolution gas field ion column with reduced sample load
A method of operating a focused ion beam device having a gas field ion source is described. According to some embodiments, the method includes emitting an ion beam from a gas field ion source, providing an ion beam column ion beam energy in the ion beam column which is higher than the final beam energy, decelerating the ion beam for providing a final beam energy on impingement of the ion beam on the specimen of 1 keV to 4 keV, and imaging the specimen. |
| US08735846B1 |
Electromagnetic biosensor
A system, method, device, and process for making and using an electromagnetic-sensitive biosensor on a biosensor disk to identify and classify an analyte in a sample. The biosensor of the biosensor disk is exposed to a sample containing analytes and a desired analyte adheres to the biosensor. The biosensor is exposed to microspheres that adhere to the analyte. The microspheres cause a detectable change to electromagnetic radiation incident upon the biosensor disk The biosensor disk is rotated during operation and an electromagnetic emitter directs an electromagnetic radiation beam at the biosensor disk. The returned electromagnetic radiation from the biosensor disk is received by a sensor and converted into a signal to indicate the presence of the desired analyte in the sample. |
| US08735843B2 |
Compounds for neutron radiation detectors and systems thereof
A material according to one embodiment exhibits an optical response signature for neutrons that is different than an optical response signature for gamma rays, said material exhibiting performance comparable to or superior to stilbene in terms of distinguishing neutrons from gamma rays, wherein the material is not stilbene, the material comprising a molecule selected from a group consisting of: two or more benzene rings, one or more benzene rings with a carboxylic acid group, one or more benzene rings with at least one double bound adjacent to said benzene ring, and one or more benzene rings for which at least one atom in the benzene ring is not carbon. |
| US08735841B2 |
Radiological image detection apparatus and method for manufacturing the same
A radiological image detection apparatus includes: a scintillator which is formed out of a group of columnar crystals in which crystals of a fluorescent material emitting fluorescence when irradiated with radiation have grown into columnar shapes; and a photodetector which is provided on a radiation entrance side of the scintillator and which detects the fluorescence emitted by the scintillator as an electric signal. A high activator density region whose activator density is higher than activator density of a region on an opposite side to the radiation entrance side in the scintillator is provided and disposed on the photodetector side in the scintillator. |
| US08735837B2 |
Gamma camera system
A gamma radiation detecting apparatus includes a gamma radiation collimator, a scintillation crystal, a charge coupled device, and an electronic device. The collimator receives and collimates gamma radiation. The scintillation crystal receives the gamma radiation from the gamma radiation collimator and converts the gamma radiation into visible light. The charge coupled device receives the visible light from the scintillation crystal and converts the visible light into an electrical charge. The electronic device converts the electrical charge into a digital image. |
| US08735836B2 |
Positron emission tomography block detector interconnect
Using standard or “off the shelf” cable to interconnect between the PET block detector and the detector circuit may save substantial costs given the number of PMTs in a PET system. Given space constraints, simple maintenance with reduced risk of disturbing cabling is desired, making ongoing use of standard cabling without adding further cabling desired. To implement digital gain control, a further communication is provided between the PET detector block and the detector circuit. Since the standard cable may not have additional wires for such communications and to reduce timing degradation, the PMT signals are combined, such as generating position and energy signals at the PET detector block. The four PMT signals are reduced to three signals without reduction in function, allowing a fourth twisted pair of wires in a CAT5 cable to be used for digital gain control. |
| US08735834B2 |
Mobile cardiac positron emission tomography (moPET) camera
A mobile PET imager and method for the same is provided. The mobile PET imager includes a plurality of detector modules forming a ring detector, each for nuclear radiation detection. The imager may include a plurality of attenuation source housings including sources for attenuation such that each attenuation source housing is placed between two of the detector modules. A plurality of channel cards for processing data from the plurality of detector modules may be in the imager so that each channel card is shared by more than one of the detector modules. The imager may include at least one channel card for processing data from the detector modules and at least one resistor network acting as preamplifier, coupling to the detector modules and the channel card such that the channel card is mounted on the detector module in layer. |
| US08735823B2 |
Terahertz-wave element, terahertz-wave detecting device, terahertz time-domain spectroscopy system, and tomography apparatus
A terahertz-wave element includes a waveguide (2, 4, 5) that includes an electro-optic crystal and allows light to propagate therethrough, and a coupling member (7) that causes a terahertz wave to enter the waveguide (2, 4, 5). The propagation state of the light propagating through the waveguide (2, 4, 5) changes as the terahertz wave enters the waveguide (2, 4, 5) via the coupling member (7). |
| US08735819B2 |
Detector system with an optical function and method for making such a system
The invention relates to a system and method for positioning and passively aligning at least one optical component as close as possible to an electromagnetic radiation detector. This system comprises supporting wedges (37) for Z positioning of the optical component (35) as close as possible to the detector (21) and passive X and Y alignment means via holding wedges and/or holding balls (36), the X, Y and Z axes being axes perpendicular to each other. |
| US08735818B2 |
Discrete dynode detector with dynamic gain control
A novel electron multiplier that regulates in real time the gain of downstream dynodes as the instrument receives input signals is introduced. In particular, the methods, electron multiplier structures, and coupled control circuits of the present invention enable a resultant on the fly control signal to be generated upon receiving a predetermined threshold detection signal so as to enable the voltage regulation of one or more downstream dynodes near the output of the device. Accordingly, such a novel design, as presented herein, prevents the dynodes near the output of the instrument from being exposed to deleterious current pulses that can accelerate the aging process of the dynode structures that are essential to the device. |
| US08735817B2 |
Clip-on target designation sensor to night vision goggles
A target engagement system includes a night vision goggle system operating within a predetermined wavelength band, and a laser module projecting light onto a target, where the light operates at a wavelength that is outside of the predetermined wavelength band. Also included is a receive system for receiving the light reflected from the target and converting the light into a wavelength within the predetermined wavelength band. In this manner, the receive system provides the converted light to the night vision goggle system, and the night vision goggle system amplifies the converted light for viewing by a user. The receive system includes a clip-on device for removably attaching the receive system between the target and the night vision goggle system. The receive system includes an up-converting phosphor layer for up-converting the received light into a wavelength detectable by the night vision goggle system. |
| US08735811B2 |
Multi-channel detection
A mass spectrometer and method of mass spectrometry wherein charged particles in a beam undergo multiple changes of direction. A detection arrangement detects a first portion of the charged particle beam, and provides a first output based upon the intensity of the detected first portion of the charged particle beam. The detection arrangement detects a second portion of the charged particle beam that has traveled a greater path length through the mass spectrometer than the first portion of the charged particle beam, and provides a second output based upon the detected second portion of the charged particle beam. A controller adjusts the parameters of the charged particle beam and/or the detection arrangement, based upon the first output of the detection arrangement, so as to adjust the second output of the detection arrangement. |
| US08735809B2 |
Chromatograph mass spectrometer
After an analysis condition table for measuring each compound is automatically generated in accordance with a compound table, the loop time is calculated for each measurement section for which the overlapping of measurement events differs. If the loop time exceeds a specified value in a given measurement section of a given compound, the event with the earliest end time and the event with the latest start time are extracted from among the overlapping measurement events, and the intermediate time between the end time and the start time is found to adjust the length of each measurement event. By repeating this process, a parameter in the analysis condition table is corrected so that the loop time becomes equal to or less than the specified value. |
| US08735808B2 |
Method of mass spectrometry and mass spectrometer using peak deconvolution
A method of mass spectrometry is disclosed wherein a signal output from an ion detector is digitized by an Analogue to Digital Converter and is then deconvoluted to determine one or more ion arrival times and one more ion arrival intensities. The process of deconvoluting the ion signal involves determining a point spread function characteristic of an ion arriving at and being detected by the ion detector. A distribution of ion arrival times which produces a best fit to the digitised signal is then determined given that each ion arrival is assumed to produce a response given by the point spread function. A plurality of ion arrival times are then combined to produce a composite ion arrival time-intensity spectrum. |
| US08735802B2 |
Optical transmission device, optical transmission/reception device, control method, and control program having heating and cooling control functions of a temperature control element
For an optical transmitter in which an EA modulator modulates a laser beam emitted from an LD, a control circuit stops heating/cooling of the EA modulator when a casing temperature (TC) is within a range of a low-temperature side reference temperature (T_cool) and a high-temperature side reference temperature (T_heat), sets a bias voltage for the EA modulator to a bias voltage corresponding to the modulator temperature based on table information recorded on a memory circuit, heats the EA modulator and sets the bias voltage corresponding to the low-temperature side reference temperature when the casing temperature is equal to or lower than the low-temperature side reference temperature, and cools the EA modulator and sets the bias voltage corresponding to the high-temperature side reference temperature when the casing temperature is equal to or higher than the high-temperature side reference temperature. |
| US08735798B2 |
Electro-optical radiation collector for arc flash detection
An electro-optical (EO) radiation collector for collecting and/or transmitting EO radiation (which may include EO radiation in the visible wavelengths) for transmission to an EO sensor. The EO radiation collector may be used with an arc flash detection device or other protective system, such as an intelligent electronic device (IED). The arc flash detection device may detect an arc flash event based upon EO radiation collected by and/or transmitted from the EO radiation collector. The EO radiation collector may receive an EO conductor cable, an end of which may be configured to receive EO radiation. A portion of the EO radiation received by the EO radiation collector may be transmitted into the EO conductor cable and transmitted to the arc flash detection device. The EO radiation collector may be adapted to receive a second EO conductor cable, which may be used to provide redundant EO transmission and/or self-test capabilities. |
| US08735793B2 |
System and method for a high dynamic range sensitive sensor element or array
A high dynamic range sensitive sensor element or array is provided which uses phase domain integration techniques to accurately capture high and low intensity images. The sensor element of the present invention is not limited by dynamic range characteristics exhibited by prior art solid-state pixel structures and is thus capable of capturing a full spectrum of electromagnetic radiation to provide a high quality output image. |
| US08735784B2 |
Microwave induction heating device
A microwave induction heating device includes microwave oscillation means (100) for oscillating a microwave so that an object is heated by the induction heating of the microwave oscillated from the microwave oscillation means (100). The microwave oscillation means (100) is configured in such a manner that the frequency of the microwave oscillated from the microwave oscillation means (100) can be changed. |
| US08735776B2 |
Hard-facing alloys having improved crack resistance
Weld deposit compositions with improved crack resistance, improved wear resistance, and improved hardness are provided by controlling matrix grain size and balancing Titanium and/or Niobium with Carbon and/or Boron content. Additionally, the presence of coarse chromium carbides is drastically decreased to reduce the amount of check-cracking. Preferably, the weld deposit is produced from a flux-cored or metal-cored wire. The weld deposit characteristics include a matrix having a fine grain size, small evenly dispersed carbides within the matrix, and a small amount of Carbon in the matrix. |
| US08735775B2 |
Hybrid wire feeder systems and methods
A hybrid wire feeder including an energy storage device and a charging circuit are provided. The hybrid wire feeder may selectively alternate between utilization of power from the energy storage device and utilization of power from a welding power supply to power the weld and one or more weld sequencing events. Some embodiments provide for the energy storage device to be adapted to discharge during periods when the welding power supply is not outputting power and to recharge from the welding power when the welding power supply is outputting power. |
| US08735770B2 |
Laser processing method for forming a modified region in an object
While a converging lens 108 is relatively moved along a line 50 including a line to cut 5, measuring laser light L2 is converged with the lens 108 when the lens 108 is positioned on a processing region 30 having an outer shape between an object to be processed 1 and a frame 22, and a reflected light component of the laser light L2 reflected by a front face 3 of the object 1 is detected. While keeping a substantially constant distance between the front face 3 and the lens 108 such that a converging point P of processing laser light L1 is positioned at a constant distance from the front face 3 according to the detection, the laser light L1 is converged by the lens 108, so as to form a molten processed region 13 within the object 1. |
| US08735768B2 |
Laser welding apparatus
A laser welding apparatus includes: a first optical element that coaxially emits, to a welded part, a laser beam emitted from a laser light source and an object beam having a different wavelength from the laser beam; a second optical element that causes the spot diameter of the object beam to be larger than the spot diameter of the laser beam on the welded part; an optical interferometer that emits the object beam to the first optical element, detects through the first optical element the object beam reflected on the welded part, and generates an electric signal based on the detected object beam; and a measuring unit that measures a penetration depth of the welded part based on the electric signal. |
| US08735765B2 |
Adjustable gap capacitively coupled RF plasma reactor including lateral bellows and non-contact particle seal
A plasma processing chamber includes a cantilever assembly and at least one vacuum isolation member configured to neutralize atmospheric load. The chamber includes a wall surrounding an interior region and having an opening formed therein. A cantilever assembly includes a substrate support for supporting a substrate within the chamber. The cantilever assembly extends through the opening such that a portion is located outside the chamber. The chamber includes an actuation mechanism operative to move the cantilever assembly relative to the wall. |
| US08735761B2 |
Welding unit for welding rails of a track
A welding unit for welding rails of a track includes two unit bodies that can be moved in relation to each other by displacement cylinders along unit guides running parallel to the rails. The displacement cylinders are connected both to pull rods and to a crossbeam. Thus a simple design having high tensile forces is possible. |
| US08735756B1 |
System and method for processing mail
A threat detection system includes a facility including at least three separate rooms located in the facility and a positive pressure zone located external to the facility. A ventilation system is coupled to the at least three separate rooms. A first room is located in the facility, wherein the first room includes a first room pressure zone that is negative with respect to the positive pressure zone external to the facility. A second room is located in the facility and connected to the first room, wherein the second room includes a second room pressure zone that is negative with respect to the first room pressure zone. A third room is located in the facility and connected to the second room, wherein the third room includes a third room pressure zone that is negative with respect to the positive pressure zone external to the facility and positive with respect to the second room pressure zone, whereby the first room pressure zone, the second room pressure zone, and the third room pressure zone result in air within the facility or entering the facility to flow into the second room. |
| US08735755B2 |
Capacitive keyswitch technologies
Described herein are techniques related to capacitance-based keyswitch technologies. According to one implementation, an apparatus includes a key with a floating electrode. The floating electrode pairs with a fixed electrode and a capacitance may be generated between them. The apparatus has a controller configured to measure the capacitance as the electrodes move relative to each other as the key is depressed and released. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. |
| US08735753B2 |
Keyboard having retracting keys for storage
Systems and apparatuses are disclosed that enable ultrathin keyboards and the storing keys of an associated physical keyboard to a storage position. The systems comprise a keycap, a keyswitch mechanism coupled to the keycap, a translatable base frame and a spring mechanism to bias the keycap into an operating position. The biasing mechanism may be an arch-shaped spring mechanism or a magnetic biasing mechanism. A portion of the biasing mechanism may be coupled to the base frame. The base frame is translatable between a first position in which the biasing mechanism imparts a force to bias the keycap into the operating position and a second position in which the portion of the biasing mechanism is repositioned such that the force to bias the keycap is at least partially eliminated. A control member may be provided to translate natural user movement into movement of the base frame for collapsing the keyboard. |
| US08735745B2 |
Device for continuously weighing a flowing bulk material exiting a conveyor
A weighing device for a bulk material conveyor, of the type that is included in the output of a tube for conveying a flow of bulk material, the device conducting the flow through the output and weighing in real time the amount of bulk material passing through the device, with the device comprising a load cell that is connected between a stationary plate and a movable plate, and a rotation sensor that records the revolutions of a rotating reference device that rotates under the effect of the flow of the bulk material passing through the weighing device. |
| US08735739B2 |
Wiring board and method for manufacturing the same
A wiring board having an insulation layer, and a buildup structure formed on the insulation layer and including insulation layers. The insulation layer and the buildup structure form a board structure in which a cavity portion having an opening on a surface of the buildup structure on the opposite side of the insulation layer is formed. The cavity portion is extending through one or more of the insulation layers in the buildup structure and has a groove portion formed on the bottom surface of the cavity portion along a wall surface of the cavity portion. The board structure composed of the insulation layer and the buildup structure has a pad formed on the bottom surface of the cavity portion in a position farther from the wall surface of the cavity portion than the groove portion. |
| US08735736B2 |
Electronic component module and its manufacturing method
The electronic component module includes a substrate; an electronic component mounted on an electronic component mounting surface of the substrate; an insulating body that covers the electronic component on the electronic component mounting surface of the substrate; and a metal film formed by electroless plating, the metal film covering an exterior surface of the insulating body and a side surface of the substrate. The substrate has a space section in which a space is formed, the space being dented inward of the substrate in the periphery of a surface opposite to the electronic component mounting surface of the substrate, and the metal film entirely covers at least one side surface of the electronic component module except for at least a portion located on a surface perpendicular to the electronic component mounting surface of the substrate in the space section. |
| US08735735B2 |
Electronic module with embedded jumper conductor
The present invention generally provides a novel method for manufacturing an electronic module with crossed conducting lines and a novel electronic module with crossed conducting lines. In particular, an aspect of the present invention is to provide a thin, single layer electronic module. It is also an object of the present invention to provide an electronic module with an embedded jumper element having reliable high quality connections and contacts. To achieve at least some of the aspects of the present invention, an embedded pre-fabricated jumper module is placed inside a printed circuit board which allows the crossing of conducting lines within the module without manufacturing additional layers over the whole PCB board. The resultant PCB will have improved contacts and will not have surface deformation. |
| US08735734B2 |
Z-directed delay line components for printed circuit boards
A Z-directed signal delay line component for insertion into a printed circuit board while allowing electrical connection to internal conductive planes contained with the PCB. In one embodiment the Z-directed delay line component is housed within the thickness of the PCB allowing other components to be mounted over it. The delay line embodiments include a W-like line and a plurality of spaced apart, semi-circular line segment connected such that current flow direction alternates in direction between adjacent semi-circular line segments, each of which in other embodiments can be varied by use of shorting bars. Several Z-directed delay line components may be mounted into a PCB and serially connected to provide for longer delays. The body may contain one or more conductors and may include one or more surface channels or wells extending along at least a portion of the length of the body. Methods for mounting Z-directed components are also provided. |
| US08735730B2 |
Touch panel and method of manufacturing the same
A non-adhering portion where an adhesion layer is removed is provided on a lower surface of a display sheet directly above a connection portion. Even if bulges or recesses occur at the connection portion on an upper substrate owing to fluctuations or differences in thickness when adhering and connecting a wiring board, no bulge or recess occurs on the display sheet. Therefore, it is possible to obtain a touch panel which is easy to see and operate. |
| US08735725B2 |
Signal transmission line disposed with conductive plastic material layer
A signal transmission line disposed with a conductive plastic material layer is provided, which relates to the field of signal transmission line technologies, and specifically to electromagnetic interference (EMI) protection of the signal transmission line. The signal transmission line at least includes a metal wire disposed with an insulation layer, a conductive plastic material layer is disposed outside the metal wire disposed with the insulation layer, and an insulation outer coating layer is disposed outside the conductive plastic material layer. A conductive plastic material layer is used as a shielding layer for EMI protection. The conductive plastic material is also called conductive polymer plastic and has characteristics such as good conductivity and good antistatic property. |
| US08735724B2 |
Electric equipment having insulation structure at welding parts
An electric equipment of the present invention has an insulation structure at a welding part formed by joining end parts of a plurality of conductors with each other, the welding part having a rectangular cross section and being coated with an insulating coating, in which the insulating coating is voidless and has a coating thickness of 50 to 1000 μm in the welding part, and in which an edge cover ratio of the insulating coating is 20% or more.According to the present invention, the insulation performance of the insulation structure in which the welding part formed by joining the end parts of the plurality of conductors with each other can be improved, the welding part having a rectangular cross section and being coated with an insulating coating, and a highly reliable electric equipment can be provided. |
| US08735720B2 |
Dye-sensitized photoelectric conversion device
Disclosed is a photoelectric conversion device wherein a methine dye represented by the formula (1) below is supported by a thin film of oxide semiconductor particles arranged on a substrate. Also disclosed is a solar cell manufactured by using such a photoelectric conversion device. (In the formula (1), n represents an integer of 0-5; m represents an integer of 0-5; R1-R4 independently represent a hydrogen atom, an optionally substituted aromatic residue, an optionally substituted aliphatic hydrocarbon residue or the like; X and Y independently represent a hydrogen atom; an optionally substituted aromatic residue, an optionally substituted aliphatic hydrocarbon residue or the like; Z represents an oxygen atom, a sulfur atom or the like; A1, A2, A3, A4 and A5 independently represent a hydrogen atom, an optionally substituted aromatic residue, an optionally substituted aliphatic hydrocarbon residue or the like; and rings a, b and c may be substituted.). |
| US08735715B2 |
Tandem photovoltaic device and method for manufacturing the same
Disclosed is a photovoltaic device that comprises: a first electrode including a transparent conductive oxide layer; a first unit cell being placed on the first electrode; a second unit cell being placed on the first unit cell; and a second electrode being placed on the second unit cell, wherein the intrinsic semiconductor layer of the first unit cell includes hydrogenated amorphous silicon or hydrogenated amorphous silicon based material, wherein an intrinsic semiconductor layer of the second unit cell includes hydrogenated microcrystalline silicon or hydrogenated microcrystalline silicon based material, and wherein a ratio of a root mean square roughness to an average pitch of a texturing structure formed on the surface of the first electrode is equal to or more than 0.05 and equal to or less than 0.13. |
| US08735714B1 |
Device for disabling a photovoltaic panel or array and photovoltaic system including the same
A device includes an enclosure mounted to an end portion of a photovoltaic panel and has an interior, an opening, an inclined ramp within the interior, a door pivotally disposed at the opening, and a latch mechanism. The door is on a panel surface in an open position, and blocks the opening in a closed position. The latch mechanism latches the door closed and releases the door to the open position. A flexible material blocks light from reaching panel photovoltaic cells and includes a first end coupled to the inclined ramp within the enclosure and an opposite second end coupled to a rod. The flexible material is rolled up about the rod and rests on the inclined ramp. The door's closed position blocks deployment of the material. In the open position, the material rolls down the inclined ramp and covers the panel surface. The door is automatically or manually deployed. |
| US08735711B2 |
Signal processing apparatus for stringed instrument
A signal processing apparatus 30 includes a FIR filter 33 that generates a signal corresponding to an instrument sound including a resonance of a body caused by a vibration of a string, based upon a pickup signal from a pickup sensor 21. The signal processing apparatus 30 guides the pickup signal from the pickup sensor 21 to an adder circuit 35 via a low-pass filter 32, guides the signal generated by the FIR filter 33 to the adder circuit 35 via a high-pass filter, and adds and mixes these signals in the adder circuit 35. The cut-off frequency of the high-pass filter 34 is equal to or higher than the cut-off frequency of the low-pass filter 32. |
| US08735700B2 |
Bearing member
A bearing member is to be used for an action mechanism in a keyboard instrument, the action mechanism provided with an action member that pivots in accordance with a key-depressing operation, and the bearing member includes: an inner layer having a through hole through which a shaft provided in the action member is inserted; and an outer layer formed in an outer side of the inner layer. The inner layer is formed of a first material having a higher stability against humidity than a stability against humidity of the outer layer. The outer layer is formed of a second material having a resilience greater than a resilience of the inner layer. |
| US08735696B1 |
Maize variety hybrid 10137650
A novel maize variety designated 10137650 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety 10137650 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 10137650 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety 10137650, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety 10137650. This invention further relates to methods for producing maize varieties derived from maize variety 10137650. |
| US08735693B1 |
Maize hybrid X08C934
A novel maize variety designated X08C934 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08C934 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08C934 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08C934, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08C934. This invention further relates to methods for producing maize varieties derived from maize variety X08C934. |
| US08735690B2 |
Maize variety and method of production
The disclosure relates to a maize plant, seed, variety, and hybrid. More specifically, the disclosure relates to a maize plant containing a Cal-1 allele, whose expression results in increased cell wall-derived glucan content in the maize plant. The disclosure also relates to crossing inbreds, varieties, and hybrids containing the Cal-1 allele to produce novel types and varieties of maize plants. |
| US08735689B1 |
Hybrid corn variety 980008
The invention provides seed and plants of the hybrid corn variety designated 980008. The invention thus relates to the plants, seeds and tissue cultures of the variety 980008, and to methods for producing a corn plant produced by crossing a corn plant of variety 980008 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety 980008. |
| US08735688B2 |
Plants and seeds of hybrid corn variety CH658401
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH658401. The invention thus relates to the plants, seeds and tissue cultures of the variety CH658401, and to methods for producing a corn plant produced by crossing a corn plant of variety CH658401 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH658401. |
| US08735686B1 |
Soybean cultivar S120117
A soybean cultivar designated S120117 is disclosed. The invention relates to the seeds of soybean cultivar S120117, to the plants of soybean cultivar S120117, to the plant parts of soybean cultivar S120117, and to methods for producing progeny of soybean cultivar S120117. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S120117. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S120117, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S120117 with another soybean cultivar. |
| US08735683B2 |
Soybean cultivar 1906039
A soybean cultivar designated 1906039 is disclosed. The invention relates to the seeds of soybean cultivar 1906039, to the plants of soybean cultivar 1906039, to the plant parts of soybean cultivar 1906039, and to methods for producing progeny of soybean cultivar 1906039. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 1906039. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 1906039, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 1906039 with another soybean cultivar. |
| US08735666B2 |
Soybean variety XR29D12
A novel soybean variety, designated XR29D12 is provided. Also provided are the seeds of soybean variety XR29D12, cells from soybean variety XR29D12, plants of soybean XR29D12, and plant parts of soybean variety XR29D12. Methods provided include producing a soybean plant by crossing soybean variety XR29D12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XR29D12, methods for producing other soybean varieties or plant parts derived from soybean variety XR29D12, and methods of characterizing soybean variety XR29D12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XR29D12 are further provided. |
| US08735665B2 |
Soybean variety XB17R12
A novel soybean variety, designated XB17R12 is provided. Also provided are the seeds of soybean variety XB17R12, cells from soybean variety XB17R12, plants of soybean XB17R12, and plant parts of soybean variety XB17R12. Methods provided include producing a soybean plant by crossing soybean variety XB17R12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB17R12, methods for producing other soybean varieties or plant parts derived from soybean variety XB17R12, and methods of characterizing soybean variety XB17R12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB17R12 are further provided. |
| US08735663B1 |
Soybean variety XBP27006
A novel soybean variety, designated XBP27006 is provided. Also provided are the seeds of soybean variety XBP27006, cells from soybean variety XBP27006, plants of soybean XBP27006, and plant parts of soybean variety XBP27006. Methods provided include producing a soybean plant by crossing soybean variety XBP27006 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP27006, methods for producing other soybean varieties or plant parts derived from soybean variety XBP27006, and methods of characterizing soybean variety XBP27006. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP27006 are further provided. |
| US08735650B2 |
Methods of modulating production of phenylpropanoid compounds in plants
A method of enhancing production of a phenylpropanoid compound in a plant or plant cell is disclosed. The method comprising: (a) expressing in the plant or plant cell a heterologous polynucleotide which produces a myb gene of the phenylpropanoid pathway; and (b) contacting the plant or plant cell with at least one substrate of the phenylpropanoid pathway, the substrate being upstream to the production of the phenylpropanoid compound, thereby enhancing the production of a phenylpropanoid compound in the plant or plant cell. |
| US08735649B2 |
Wheat having reduced waxy protein due to non-transgenic alterations of a waxy gene
A series of independent non-transgenic mutations found at the waxy loci of wheat; wheat plants having these mutations in their waxy loci; and a method of creating and finding similar and/or additional mutations of the waxy by screening pooled and/or individual wheat plants. The wheat plants of the present invention exhibiting altered waxy activity in the wheat without having the inclusion of foreign nucleic acids in their genomes. The invention also includes food and non-food products as well as non-food products that incorporate seeds from the wheat plants having non-transgenic mutations in one or more waxy genes. |
| US08735646B2 |
Diaper with improved body fit
An absorbent article that has a thin, conformable absorbent core where the core has at least two layers, both of which are substantially free of cellulosic fibers is described. The first layer is intended to provide storage for the majority of acquired fluids and has an AAP of at least about 20 g/g and the second layer, which provides temporary capacity for the bulk of the acquired fluid and permanent storage for at least a portion thereof, comprises a second absorbent polymer material which has a Wet Permeability of at least about 400×10−7 (cm3 seconds)/g a ratio of Wet Permeability to SFC of at least about 1.5:1 with respect to the first absorbent polymer material. |
| US08735644B2 |
Biocompatible wound dressing
A biocompatible wound dressing comprised of a pad for insertion substantially into a wound site and wound drape for sealing enclosure of the foam pad at the wound site. The pad, comprised of a foam or other like material having relatively few open cells in contact with the areas upon which cell growth is to be encouraged so as to avoid unwanted adhesions, but having sufficiently numerous open cells so that drainage and negative pressure therapy may continue unimpaired, is placed in fluid communication with a vacuum source for promotion of fluid drainage, as known in the art. The pad is further comprised of an ultra-low density fused-fibrous ceramic, or a bioabsorbable branched polymer, or cell growth enhancing matrix or scaffolding. |
| US08735643B2 |
Aggregate zeolitic absorbents, their method of preparation and their uses
The invention relates to aggregate zeolitic adsorbents based on faujasite X type zeolite powder having a low silica content and small crystals, exchanged with barium or based on faujasite X type zeolite having a low silica content and small crystals, exchanged with barium and potassium.The invention also relates to the method for preparing said aggregate zeolitic adsorbents, and also their uses for separating sugars, polyhydric alcohols, isomers of substituted toluene, cresols, or for recovering very high purity paraxylene. |
| US08735641B2 |
Method for selective dealkylation of alkyl-substituted C9+ aromatic compounds using bimodal porous dealkylation catalyst at low temperature
Disclosed is a method for selective dealkylation of alkyl-substituted C9+ aromatic compounds using a bimodal porous dealkylation catalyst at a low temperature. The catalyst has a bimodal porous structure including both mesopores and micropores. The catalyst includes a crystalline aluminosilicate and a metal. The catalyst is highly active at a low temperature. According to the method, C9+ aromatic compounds substituted with at least one C2+ alkyl group as by-products formed by xylene production can be selectively dealkylated and converted to BTX, etc. on a large scale within a short time. In addition, the method is an environmentally friendly process entailing reduced waste treatment cost when compared to conventional mesitylene production methods. Therefore, high value-added mesitylene can be separated from low value-added C9+ aromatic compounds at lower cost compared to conventional methods. Furthermore, the supported metal catalyst is easy to recover after dealkylation and is recyclable, thereby contributing to reduced cost. |
| US08735640B2 |
Methods of refining and producing fuel and specialty chemicals from natural oil feedstocks
Methods are provided for refining natural oil feedstocks. The methods comprise reacting the feedstock with a low-molecular-weight olefin or mid-weight olefin in the presence of a metathesis catalyst under conditions sufficient to form a metathesized product comprising olefins and esters. In certain embodiments, the methods further comprise separating the olefins from the esters in the metathesized product. In certain embodiments, the methods further comprise transesterifying the esters in the presence of an alcohol to form a transesterified product. |
| US08735633B2 |
Methods for making 1,3-dihydroxyacetone (DHA) from glycerol
A method comprising reacting glycerol with acetaldehyde or 1,1-diethoxyethane to produce 1,3-dihydroxyacetone (DHA), without using fermentation or direct oxidation of the glycerol is provided. DHA is useful in various products, including as a sunless tanning agent. |
| US08735631B2 |
Method for manufacturing methylmercaptopropionaldehyde and methionine using renewable raw materials
The present invention relates to a method for manufacturing methylmercaptopropionaldehyde (MMP) including at least the following steps: (a) dehydrating glycerol to acrolein from an aqueous solution of glycerol in the presence of an acid catalyst; (b) purifying the aqueous flux from step (a) to obtain a flux of acrolein containing at least 15 wt % of water relative to the acrolein; (c) causing a reaction of the acrolein flux obtained in step (b) with methylmercaptan in the presence of a catalyst; (d) optionally purifying the product obtained in step (c). The method of the invention can also include a reaction of the product obtained in step (c) or (d) with hydrocyanic acid, or sodium cyanide during a step (e) followed by a subsequent transformation to produce methionine or methionine hydroxyanalogue, which can then optionally be purified. The additional use of methylmercaptan and/or hydrocyanic acid derived from biomass as raw materials in the method according to the invention makes it possible to obtain MMP, methionine or methionine hydroxyanalogue made up of 100% organic carbon from renewable sources. |
| US08735630B2 |
Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions
One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in various transition-metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition-metal-catalyzed reactions, including the range of suitable substrates, number of catalyst turnovers, reaction conditions, and efficiency. For example, improvements have been realized in transition metal-catalyzed: aryl amination reactions; aryl amidation reactions; Suzuki couplings; and Sonogashira couplings. In certain embodiments, the invention relates to catalysts and methods of using them that operate in aqueous solvent systems. |
| US08735626B2 |
Method of producing aromatic amino compounds
A method of producing an aromatic amino compound using a primary or secondary amine compound and a halogenated aromatic compound as starting materials, and relying upon the Ullmann reaction, the method being capable of obtaining the highly pure aromatic amino compound in high yields and inexpensively. A primary or secondary amine compound having an aromatic ring group and a halogenated aromatic compound as starting materials, are reacted with the halogenated aromatic compound in the presence of copper catalyst and base to produce the aromatic amino compound having a structure in which an aromatic ring group derived from the halogenated aromatic compound is coupled to the amino group of the amine compound, wherein the amine compound and the halogenated aromatic compound are reacted together such that an aromatic oxycarboxylic acid having a hydroxyl group and a hydroxycarbonyl group bonded to neighboring carbon atoms, is present together with the copper catalyst and the base. |
| US08735624B2 |
Polymorphic form of CHDMAPP, method of preparation thereof, and pharmaceutical composition comprising same
The present invention relates to novel polymorphs of (2E)-1-hydroxy-2-methylpent-2-enyl-pyrophosphonate disodium (CHDMAPP-Na2), to the process for preparing them and to the pharmaceutical compositions containing them. |
| US08735623B2 |
Process for preparing creatine amides
The invention relates to the field of pharmaceutical chemistry, specifically to processes for preparing biologically active substances (BAS), in particular creatine amides. What is proposed is a process for preparing creatine amides which comprises treating creatine with para-toluenesulfonic acid in an organic solvent with subsequent reaction of the resultant complex with compounds comprising a primary or secondary amino group in the presence of a condensing agent and a base which are introduced subsequently. The claimed process makes it possible to increase the yield of the end product by 2-5 times in comparison with known similar processes and also to extend the range of the compounds prepared. |
| US08735622B2 |
Histone demethylase inhibitors and methods for using the same
The present invention provides compounds, or derivatives or prodrugs thereof, that comprise a methyllysine mimic, and an α-ketoglutarate mimic that are attached through a linker and methods for using and producing the same. In some embodiments, compounds of the invention are of the formula: M-L-K, or a derivative or a prodrug thereof, wherein M is a methyllysine mimic, L is a linker, and K is an α-ketoglutarate mimic. |
| US08735609B2 |
Bryostatin analogues, synthetic methods and uses
Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and utilizing the same. |
| US08735603B2 |
N-substituted pyrrolidonium ionic liquids with expanded linker
This invention relates to compounds useful as ionic liquids that are based on an N-substituted pyrrolidinone and incorporate a pendant ammonium cation that is spaced from the pyrrolidone ring by a variable length linker. |
| US08735602B2 |
Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
The present invention relates to pharmaceutically acceptable crystalline and amorphous salts of D-isoglutamyl-D-tryptophan as well as processes for their manufacture, pharmaceutical compositions comprising them, and their uses in the preparation of pharmaceutical compositions for the treatment of various conditions and/or diseases. In particular, the present invention relates to D-isoglutamyl-D-tryptophan potassium salt (1:1), D-isoglutamyl-D-tryptophan lithium salt (1:1), D-isoglutamyl-D-tryptophan calcium salt (2:1), D-isoglutamyl-D-tryptophan magnesium salt (2:1), and D-isoglutamyl-D-tryptophan organic ammonium salts (1:1). |
| US08735598B2 |
Method for producing 1-biphenylmethylimidazole compound
The present invention provides a method for producing a 1-biphenylmethylimidazole compound having superior angiotensin II receptor antagonistic activity, or an intermediate thereof.The present invention provides a method for producing a compound having the formula (5) (R1, Ra: H, an alkyl group) by oxidizing a compound having the formula (1) (Ra: H, an alkyl group) using an oxidizing agent in the presence of a radical initiation reagent, and then reacting with an ammonia-generating reagent and a compound having the formula R1CHO(R1: H, an alkyl group) or a compound having the formula R1C(ORb)3 (R1: H, an alkyl group; Rb: an alkyl group). |
| US08735597B2 |
Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using benzoxazole derivative
Disclosed is a novel benzoxazole derivative which has high excitation energy, particularly high triplet excitation energy, and is a bipolar substance. A benzoxazole derivative represented by the following General Formula (G1) is provided. In the formula, R1 and R2 independently represent a hydrogen atom, an alkyl group with 1 to 4 carbon atoms, or a substituted or unsubstituted aryl group with 6 to 13 carbon atoms, substituents of the substituted aryl group may be bonded to form a ring which may form a spiro ring structure, R11 to R14 independently represent a hydrogen atom, a halogen, an alkyl group with 1 to 4 carbon atoms, or an unsubstituted aryl group with 6 to 10 carbon atoms, a bond formed between any two of α, β, and γ forms a carbazole skeleton, and n is 0 to 3. |
| US08735588B2 |
Nematocidal sulfonamides
Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Z is O or S; and R1, R2, R3, Q and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or a composition of the invention. |
| US08735586B2 |
Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides. |
| US08735584B2 |
Protein kinase inhibitors and use thereof
Disclosed are benzonaphthyridinyl derivative compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to kinase signal transduction inhibition, regulation or modulation. |
| US08735582B2 |
Method for producing carboxylic anhydride and arylboronic acid compound
When phthalic acid is heated in heptane under azeotropic reflux conditions in the presence of a catalytic amount of an arylboronic acid compound (such as 2,6-(diisopropylaminomethyl)phenylboronic acid or 2,6-bis(diisopropylaminomethyl)phenylboronic acid), phthalic anhydride is obtained in high yield. |
| US08735579B2 |
Benzamides, production thereof, and use thereof as medicaments
Heteroaryloxy-substituted benzoic acid amides of general formula I wherein the groups R1 to R7 as well as X and Y are defined according to claim 1, including the tautomers, the stereoisomers, the mixtures and the salts thereof. The compounds according to the invention are suitable for the treatment of respiratory complaints, particularly COPD and asthma. |
| US08735577B2 |
1,3,5-triazine derivative, process for producing same, and organic electroluminescent element comprising same as constituent component
A 1,3,5-triazine derivative represented by the formula (1): wherein R1, R2 and R3 each independently represent a hydrogen atom or a methyl group; X represents a carbon atom or a nitrogen atom; Ar1 represents a substituted or unsubstituted aromatic hydrocarbon group; Ar2 represents an C1-4 alkyl-substituted or unsubstituted aromatic 6-membered heterocyclic group having one or two nitrogen atoms, which may be a condensed ring compound. An organic electroluminescent device comprising the 1,3,5-triazine derivative exhibits low power consumption and long lifetime. |
| US08735576B2 |
Benzothiazole derivatives
Provided are compounds and their pharmaceutically acceptable salts that are useful for the treatment of diseases related to the adenosine receptor. Also included are methods of treating patients suffering from or susceptible to at least one symptom of abuse of, dependence on, or withdrawal from at least one substance. |
| US08735573B2 |
Method to recover bioactive compounds
The invention relates to a process for separating bioactive compounds obtained from vegetable materials. The invention also relates to a process for extracting bioactive compounds from vegetable material. |
| US08735572B2 |
Cellulose ester compositions having low birefringence and films made therefrom comprising a plasticizer
The present inventions relate to cellulose esters having low hydroxyl content for use in optical applications, such as liquid crystal display (LCD) films. Films with low hydroxyl levels and a given ratio of non-acetyl ester to hydroxyl level have low intrinsic birefringence. These films can be cast, molded, or otherwise oriented without an appreciable birefringence or optical distortion (i.e. retardation). These films are useful in polarizer, protective, and compensator films and in molded optical parts, such as lenses. The resins of the present inventions can also be made to have “+C plate” behavior either by melt or solvent based processing, which is uncharacteristic of cellulose esters. Such +C behavior allows films having unique compensatory behavior. Other embodiments of the invention relate to methods of melt casting films while minimizing birefringence. Another embodiment of the invention is directed to films made from the cellulose esters described herein further comprising a plasticizer. |
| US08735571B2 |
Composition, preparation, and use of dense chitosan membrane materials
A composition of exceptionally dense chitosan and a novel method for producing the dense chitosan structure have been described. The novel production method employs coincident compression and vacuum on a neutralized chitosan polymer that results in an exceptionally dense chitosan film or membrane material. The dense chitosan film or membrane composition possesses multiple physical and clinically appealing qualities for a variety of medical applications on or in animals, mammals, or humans. |
| US08735569B2 |
Nucleoside phosphoramidates
Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals. |
| US08735567B2 |
Multi-targeted RNAi therapeutics for scarless wound healing of skin
The present invention provides small interfering RNA (siRNA) molecules, compositions containing them, and methods of using them for improvement of skin scarless wound healing and other skin conditions, such as psoriasis and lupus-caused cutaneous lesions. The invention includes siRNA molecules and compositions containing them that inhibit the expression of one or more genes that promote pathological or undesired processes in wound healing and methods of using them. |
| US08735564B2 |
Fast results hybrid capture assay and system
The present invention comprises a method that provides fast and reliable results for detecting the presence of a target nucleic acid molecule in a sample. |
| US08735563B2 |
Polynucleotides having promoter activity
The present invention relates to isolated polynucleotides having promoter activity the juse of the isolated polynucleotides for the procuction of a polypeptide. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing a desired polypeptide using the polypeptide having promoter activity. |
| US08735559B2 |
Mutant protease biosensors with enhanced detection characteristics
A polynucleotide encoding a biosensor polypeptide comprising a modified circularly-permuted thermostable luciferase and a linker linking the C-terminal portion of the thermostable luciferase to the N-terminal portion of the thermostable luciferase. The modified circularly-permuted thermostable luciferase is modified relative to a parental circularly-permuted thermostable luciferase. The linker contains a sensor region capable of interacting with a target molecule in a cell. The modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the parental circularly-permuted thermostable luciferase in the presence of the target molecule. Alternatively, the modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the modified circularly-permuted thermostable luciferase in the absence of the target molecule. |
| US08735558B2 |
Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof
This invention provides methods, processes, compounds and compositions for modulating the gene expression and modulating the secretion, expression, or synthesis of adhesion proteins or their receptors to cure disease, wherein the modulating comprises positive and negative regulating; wherein comprises inhibiting cancer growth, wherein the adhesion proteins or receptors comprise fibronectin, integrins family, Myosin, vitronectin, collagen, laminin, Glycosylation cell surface proteins, polyglycans, cadherin, heparin, tenascin, CD 54, CAM, elastin and FAK; wherein the methods, processes, compounds and compositions are also for anti-angiogenesis; wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, prostate cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, CNS cancer, melanoma cancer, renal cancer or cervix cancer. |
| US08735554B2 |
Reagents, methods, and systems for detecting methicillin-resistant Staphylococcus
The present invention provides PBP2a peptide antigens for generating antibodies against MRSA, and provides high-affinity binding agents that detect MRSA by selective immunoreactivity with PBP2a. The antibodies are useful in methods and systems for detecting MRSA, including biosensor systems, or as components of diagnostic or detection kits. The antibodies, in some embodiments, have therapeutic value against MRSA infection. |
| US08735551B2 |
Antibodies for epidermal growth factor receptor 3 (HER3)
The present invention relates to antibodies or fragments thereof that target a conformational epitope of a HER receptor. In particular, the invention relates to antibodies or fragments thereof that target a conformational epitope of HER3 receptor and compositions and methods of use thereof. |
| US08735543B2 |
Chimeric MOMP antigen
The present invention regards polypeptides capable of eliciting an immunological response that is protective against Chlamydia trachomatis. The polypeptide comprises a first amino acid sequence which has at least 90% homology with the amino acid sequence according to SEQ ID NO: 1 and a second amino acid sequence which has at least 90% homology with the amino acid sequence according to SEQ ID NO: 2. Furthermore, production of these polypeptides and pharmaceutical compositions comprising them are also provided. |
| US08735541B2 |
α-Conotoxin peptides
The invention relates to relatively short peptides (termed α-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds. |
| US08735540B2 |
Peptides with sequentially arranged streptavidin binding modules
The present invention relates to sequentially arranged streptavidin-binding binding modules which may in particular be used as affinity tags. The affinity tags comprise at least two individual modules capable of mediating avidic binding to streptavidin. |
| US08735538B1 |
Use of methanobactin
The invention provides compositions comprising and methods employing methanobactin, as well as methanobactin synthetase sequences. |
| US08735536B2 |
Naphthobisthiadiazole polymers for use in organic semiconductor devices
Disclosed are new semiconducting polymers. The polymers disclosed herein can exhibit high carrier mobility and/or efficient light absorption/emission characteristics, and can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions. |
| US08735530B2 |
Polyamide manufacturing process
A method for making polyamide is described. More particularly, a method for making a polyamide from at least one diacid and one diamine, that includes a step of concentrating an aqueous solution of diacid and diamine salt up to a salt weight concentration higher than 85%, and a polymerization step up to a desired polymerization degree is described. |
| US08735527B2 |
Laminating adhesive
[Solution to Problem] The laminating adhesive of the present invention includes a polyisocyanate component (A) and a polyol component (B), wherein the polyisocyanate component (A) contains a polyisocyanate (A1) that does not contain an aromatic ring, and the polyol component (B) contains a macropolyol (B1) that does not contain an aromatic ring but contains a cyclohexane ring. |
| US08735523B2 |
Polymer crystalline materials
One embodiment of the present invention provides polymer crystalline materials containing crystals of the polymer and satisfying the following requirements (I) and (II) or the following requirements (I) and (III): (I) the polymer crystalline materials a crystallinity of 70% or greater; (II) the crystals are 300 nm or less in size; and (III) the crystals have a number density of 40 μm−3 or greater. This allows an embodiment of the present invention to provide polymer crystalline materials which are excellent in properties such as mechanical strength, heat tolerance, and transparency or, in particular, polymer crystalline materials, based on a general-purpose plastic such as PP, which is excellent in properties such as mechanical strength, heat tolerance, and transparency. |
| US08735519B2 |
Polyolefin produced with a high performance support for a metallocene catalyst system
The invention is directed to a metallocene catalyst system and a process for preparing the system. The metallocene catalyst system comprises a support and metallocene bound substantially throughout the support. The selection of certain supports facilitates the production of metallocene catalyst systems having increased catalytic activity than previously recognized. |
| US08735512B2 |
Curing agent for low temperature cure applications
The present invention provides Mannich base derivatives of N,N′-dimethyl secondary diamine polymers including Mannich base derivatives of methylamine-terminated poly-(N-methylazetidine) and Mannich base derivatives of methylamine-terminated poly-(N-methylazacycloheptane). Amine curing agent compositions and amine-epoxy compositions containing Mannich base derivatives of N,N′-dimethyl secondary diamine polymers are also disclosed. |
| US08735510B2 |
Polymer composition
A polymer composition comprising: at least one polycondensation polymer having a heat deflection temperature (HDT) of above 80° C. under a load of 1.82 MPa when measured according to ASTM D648 [polymer (P)]; at least one perfluoropolyether block copolymer [polymer (F)] comprising: A) one or more (per)fluoropolyoxyalkylene segment (chain Rf) comprising recurring units having at least one catenary ether bond and at least one fluorocarbon moiety, and B) one or more polyalkylene segment (chain Ra) comprising recurring units of formula: —(CR1R2—CR3R4)—; wherein R1, R2, R3, R4, equal to or different from each other, are selected from the group consisting of H, halogens; C1-C6 (hydro)carbon groups, optionally containing fluorine or other heteroatoms, to a process for its manufacture and to its use for manufacturing shaped articles, in particular by extrusion molding or injection molding techniques. |
| US08735506B2 |
Ultraviolet radiation curable pressure sensitive acrylic adhesive
A process for making UV curable pressure sensitive adhesive compositions by derivatizing an acrylic polymer with a derivatizing agent prepared from a hydroxy-functional acrylate monomer and a diisocyanate. The derivatizing agent typically has a ratio of hydroxy-functional acrylate monomer to diisocyanate greater than about 1:1. Also disclosed are UV curable pressure sensitive adhesives made with the derivatizing agent and methods for adhering substrates with pressure sensitive adhesive compositions. |
| US08735504B2 |
Methods for preparing polymers having low residual monomer content
Methods are provided for preparing polymer mixtures having low residual monomer content. The methods comprise mixing the at least two polymers in a solvent to form a polymeric mixture, the polymeric mixture comprising at least one residual monomer; and adding an antisolvent to the polymeric mixture so as to separate the at least two polymers from the polymeric mixture, where the residual monomer is soluble in the antisolvent. In some embodiments, methods are provided for preparing at least two polymers having low residual monomer content, the methods comprise adding an antisolvent to a mixture of at least two polymers dissolved in a solvent so as to precipitate the at least two polymers from the solvent and anti-solvent. The methods provided avoid steps in dry blending of polymers and produces polymer blends that have low residual monomer content. |
| US08735497B2 |
Propylene polymers compositions
A propylene composition comprising (percent by weight): A) 60%-95%, of a crystalline propylene copolymer containing from 2.0% to 10.0% of ethylene derived units having a melting point ranging from 148° C. to 160° C.; wherein the melting temperature Tm is measured by DSC on the as-reactor polymer; B) 40%-5%, of a copolymer of ethylene containing from 70% to 85%, of ethylene derived units intrinsic viscosity ranging from 0.8 to 3 dl/g. |
| US08735496B2 |
Method for producing hydrophilic poly-N-vinylpyrrolidone and use thereof
The present invention relates to a process for the production of the largest possible spherical, monodisperse polyvinylpyrrolidone (PVP) seed particles in the micron range by dispersion polymerisation. The particles obtained in this way represent novel starting materials for the production of macroporous polymer particles, which can in turn be employed in preparative and analytical chromatography for protein preparation. They can also be employed as base material for further reactions.The novel process for the polymerisation of N-vinylpyrrolidone, which is inexpensive to carry out, gives particles having optimised quantities, such as monodispersity, sphericity and particle diameter, which can be employed in further reactions and have advantageous, in particular improved, properties for use in chromatographic separation methods. |
| US08735486B2 |
Flame-retardant resin composition, process for producing the same, method of molding the same
An exterior body of an electric appliance is produced by kneading one or more resin components and one or more flame retardancy-imparting components to give a composition, and molding the composition by an injection molding method or a compression molding method. At least one of the flame retardancy-imparting components is a catalytic cracking catalyst and the catalytic cracking catalyst is a silica-magnesia catalyst which is double oxide of silicon oxide and magnesium oxide or which is formed by binding silicon oxide and magnesium oxide. The at least one flame retardancy-imparting component is contained in an amount of 0.5 wt % to 40 wt % of the resin composition. No metal hydroxide and no polyvinyl chloride are contained in the composition. |
| US08735481B2 |
Self-lubricating surface coating composition for low friction or soft substrate applications
A bearing having a surface and a self-lubricating surface coating composition deposited on the surface, wherein the self-lubricating surface coating composition includes a curable acrylate composition having a metallic composition. The metallic composition having a metallic acrylate compound according to Formula I: and about 30 mass % to about 45 mass % PTFE fiber. |
| US08735478B2 |
Aqueous coating material and painted article
The present invention relates to an aqueous coating material containing polymer (I), colloidal silica (II), and nonionic surfactant (III) with an HLB value of 16 or more. The polymer (I) is obtained by copolymerization of monomer mixture (M) that contains 0.2 to 10% by mass of monomer (a) having two or more radically polymerizable groups. The solid content of the colloidal silica (II) is 0.1 to 20 parts by mass with respect to 100 parts by mass of the polymer (I). The content of the nonionic surfactant (III) is 0.01 to 10 parts by mass with respect to 100 parts by mass of the polymer (I). The present invention also relates to a painted article where the aqueous coating material is applied. Therefore, an aqueous coating material and a painted article capable of expressing stain resistance and weather resistance can be provided by reducing a water contact angle. |
| US08735471B2 |
Polyolefin dispersions, froths, and foams
Polyolefin dispersions, froths, and foams and articles manufactured therefrom are disclosed. Also disclosed is a method for generating a thermoplastic foam from an aqueous dispersion. The aqueous dispersion may include a thermoplastic resin, water, and a stabilizing agent. The method may include adding at least one frothing surfactant to the aqueous dispersion to form a mixture, adding a flame retardant and/or a phase change material, frothing the mixture to create a froth, and removing at least a portion of the water to produce the foam. |
| US08735468B2 |
Extrusion method and a plant therefor
A method for extrusion of polymer products is provided. The method includes preparing a base mixture in a turbomixer the base mixture containing polymer powders and at least an additive. The method also includes introducing the base mixture into at least an extruder, via a mixer into which an additional quantity of the additive and/or at least a further additive is introduced. |
| US08735465B2 |
Denture adhesive compositions
Denture adhesive compositions having good hold and improved taste containing a salt of a copolymer of alkyl vinyl ether-maleic acid or anhydride. Compositions containing from about 25% to about 45%, by weight of the composition, of a salt of a copolymer of alkyl vinyl ether-maleic acid or anhydride containing a cationic salt function containing: i) from about 60% to about 72% cations selected from calcium, strontium, magnesium, or combinations thereof; ii) from 0% to about 10% sodium cations; iii) less than 1% zinc cations; and iv) from about 25% to about 40% of a free acid component; and further containing from about 15% to about 25%, by weight of the composition of a carboxymethyl cellulose having a molecular weight of from about 200,000 to about 1,000,000 daltons; and a carrier. Methods of improving the adhesion of dentures to the oral cavity by applying such compositions to dentures, the oral cavity, or both, and thereafter securing the denture to the ridge or palate of the oral cavity. |
| US08735464B2 |
Radically curable urethane dimethacrylates and compositions thereof for tougher dental prosthetics
A radically curable polyurethane composite for dental restorations, including provisional restorations, includes polyurethane dimethacrylate prepolymers that have at least one flexible unit within a polyurethane dimethacrylate backbone, and one or more dimethacrylate monomers. Composite materials made with polyurethane dimethacrylate prepolymers of the invention exhibit superior and optimal properties of flexural strength and deflection-at-break relative to conventional dental resin composites. Composite materials of the invention also provide improved melt-resistance in response to the heat of grinding or finishing, thereby improving the fit of restorations made from the composite and preserving the finishing instruments. Methods of treating a tooth using the radically curable polyurethane composite and methods of making the polyurethane dimethacrylate prepolymers with flexible units is also provided. A kit including the radically curable polyurethane composite is also described. |
| US08735463B2 |
Self-healing dental composites and related methods
Dental restorative composites having self-healing capabilities to repair discontinuities in the composite are provided. Dental restorative composites according to the present invention include a microsphere that encapsulates a monomer. When a fracture occurs, the microsphere is ruptured and the monomer fills the fracture. Depending on the monomer present in the microsphere, it is polymerized by a polymerization initiator or by an olefin metathesis catalyst present in the dental restorative composite. Self-healing dental restorative composites provide increased resistance to fracturing, and thus remain substantially intact for a longer period of time, preserving the remedial integrity of the dental repair or reconstruction. |
| US08735459B2 |
Composition for preparing expandable polypropylene carbonate and expandable polypropylene carbonate prepared therefrom
Provided are a composition for preparing expandable polypropylene carbonate and an expandable polypropylene carbonate prepared therefrom, and more particularly, to a composition for preparing expandable polypropylene carbonate capable of using supercritical carbon dioxide as a foaming agent and producing a foam having excellent moldability by using an appropriate foaming method. By using the composition according to the present invention, highly magnificated expandable polypropylene carbonate capable of having excellent thermal stability and dimensional stability can be prepared. |
| US08735457B2 |
Recycled polyethylene terephthalate compositions, fibers and articles produced therefrom, and methods for producing same
In one aspect, the invention relates to recycled polyethylene terephthalate compositions, fibers and articles produced therefrom, and methods for producing same. In a further aspect, the invention relates to homogenized post-consumer polyethylene terephthalate. In a further aspect, the invention relates to extruded polymer compositions, polymer mixtures, fibers, and/or Bulked Continuous Filament fibers comprising post-consumer polyethylene terephthalate. In a further aspect, the invention relates to processes for preparing recycled polyethylene terephthalate compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| US08735453B2 |
Lipids, lipid complexes and use thereof
The present invention is related to uses of a composition comprising a pharmaceutically active component and a compound according to formula (I), wherein R1 and R2 are each and independently selected from the group comprising alkyl; n is any integer between 1 and 4; R3 is an acyl selected from the group comprising lysyl, ornithyl, 2,4-diaminobutyryl, histidyl and an acyl moiety according to formula (II), wherein m is any integer from 1 to 3 and Y− is a pharmaceutically acceptable anion. |
| US08735450B2 |
Formulation of diclofenac
The present invention relates to methods for producing particles of diclofenac using dry milling processes as well as compositions comprising diclofenac, medicaments produced using diclofenac in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of diclofenac administered by way of said medicaments. |
| US08735437B2 |
Imidazolidine carboxamide derivatives as lipase and phospholipase inhibitors
The present invention relates to imidazolidinecarboxamide derivatives of the general formula I, wherein R, R1, R2, X and Y are as defined herein, or pharmaceutically usable salts thereof and the use thereof as medicinal substances. |
| US08735432B2 |
N-(Heteroaryl)-1-heteroarylalky1-1H-indole-2-carboxamide derivatives, preparation and therapeutic use thereof
The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Y and W are as defined herein. The invention also concerns a method for preparing said compounds and their therapeutic use. |
| US08735431B2 |
Active compound combinations having insecticidal properties
The invention relates to novel insecticidal active compound combinations comprising, firstly, anthranilamides and, secondly, further insecticidally active compounds as defined in the description, which combinations are highly suitable for controlling animal pests, such as insects. |
| US08735430B2 |
Compounds which selectively modulate the CB2 receptor
Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain. |
| US08735426B2 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions
Compounds corresponding to formula I: which act as vanilloid receptor ligands, pharmaceutical compositions containing such compounds, a process for the producing such compounds, and the use thereof to treat or inhibit pain and/or various other disorders or conditions. |
| US08735425B2 |
Tetrahydroisoquinoline derivative
The present invention relates to a compound or a pharmacologically acceptable salt thereof having an excellent DGAT inhibitory effect and feeding suppressant effect. The present invention provides a compound represented by the general formula (I), or pharmacologically acceptable salt thereof: [wherein, R1 represents a phenylaminocarbonyl group that may be substituted with 1 to 5 group(s) independently selected from Substituent Group A, a benzoxazol-2-yl group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group A, or the like; R2 independently represents a C1-C6 alkyl group; R3 represents a group represented by the formula —C(═O)—O—R4 or the like; R4 represents a hydrogen atom, a C1-C6 alkyl group that may be substituted with 1 to 3 group(s) independently selected from Substituent Group B, or the like; X represents an oxygen atom, a methylene group, or a group represented by the formula —NH—, or the like; L represents a single bond, a methylene group, or the like; . . . represents a single bond or a double bond; m represents 1 or 2; n represents an integer of 0 to 5; Substituent Group A represents a halogen atom, a C1-C6 alkyl group, a C1-C6 halogenated alkyl group, a C1-C6 alkoxy group, or the like; and Substituent Group B represents a C3-C6 cycloalkyl group, a phenyl group, a carboxyl group, or the like]. |
| US08735423B2 |
Bicyclic compounds as α4β2 nicotinic acetylcholine receptor ligands
The present invention relates to novel bicyclic compounds of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. These compounds are useful in the treatment and prevention of various disorders that are related to α4β2 nicotinic receptors. |
| US08735418B2 |
Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
This invention is directed to compounds of formula (I): where n, m, Y, R1, R2, R3, R4 and R5 are disclosed herein, as isolated stereoisomers or mixtures thereof, or pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising the compounds of formula (I); and methods of using the compounds and the pharmaceutical compositions in treating diseases or conditions associated with JAK2 activity. |
| US08735416B2 |
Antiviral therapies
The field of the invention relates to the use of carbohydrate binding compounds as a medicine, their use to treat or prevent viral infections, their use to manufacture a medicine to treat or prevent viral infections and their use in a vaccination strategy. The present invention relates to the use of said compounds to manufacture a medicine to treat or prevent viral infections of subject, more in particular infections with viruses having glycosilated envelope proteins such as Retroviridae (i.e., Lentivirinae), like HIV (human immunodeficiency virus), Flaviviridae, like HCV (hepatitis C virus), Hepadnaviridae, like HBV (hepatitis B virus), Coronaviridae, like SARS corona virus, and Orthomyxoviridae, like influenza A, B, or C. |
| US08735414B2 |
Indole derivatives and methods for antiviral treatment
The present invention is directed to compounds and forms and pharmaceutical compositions thereof useful for treating a viral infection, or for affecting viral activity by modulating viral replication. |
| US08735413B2 |
Compound
There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. The compound is useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial. |
| US08735412B2 |
Sulfoximine-substituted anilinopyrimidine derivatives as CDK inhibitors, the production thereof, and use as medicine
The invention relates to sulfoximine-substituted anilino-pyrimidine derivatives of formula (I). methods of production thereof, and use thereof as medication for the treatment of various diseases. |
| US08735407B2 |
Purine derivatives as A3 adenosine receptor-selective agonists
Disclosed are (N)-methanocarba adenine nucleosides, e.g., of formula (I) as highly potent A3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R1-R6 are as defined in the specification. These nucleosides exhibit similar selectivities as agonists of the A3 versus the A1 receptor for both human and mouse adenosine receptors, and are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. |
| US08735404B2 |
Inhibitors of Bruton's tyrosine kinase
Disclosed herein are compounds, including compounds having the structure of Formula (A), (B), (C), and (D), as described in further detail herein, that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. |
| US08735403B2 |
Inhibitors of Bruton's tyrosine kinase
Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. |
| US08735401B2 |
Thienopyrimidine compounds and use thereof
The present invention provides a compound represented by the formula: wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a hydroxy group, (3′) a C1-4 alkyl and (4′) a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a C1-4 alkoxy-C1-4 alkyl, (3′) a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4′) a C1-4 alkoxy and (5′) a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity. |
| US08735399B2 |
Selective subtype alpha 2 adrenergic agents and methods for use thereof
The invention provides oxazolidine and thiazolidine derivatives that are useful as subtype selective alpha 2 adrenergic agonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with selective subtype modulation of alpha 2 adrenergic receptors. |
| US08735396B2 |
Benzofuranyl derivatives
The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. |
| US08735393B2 |
Anhydrous topical skin preparations
The present invention provides anhydrous compositions for topical delivery of a medicament comprising (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol, or any combination of any of the foregoing; and (C) an anhydrous vehicle. In an alternate embodiment, the present invention provides anhydrous compositions for topical delivery of a medicament which comprise (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol or any combination of any of the foregoing; (C) an anhydrous vehicle; and (D) a medicament. Also provided are methods for topically delivering a medicament to an animal. |
| US08735392B2 |
Crystalline (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt
Provided herein are (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt are also provided, as are methods of using (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt to treat a disease or condition, such as a cancer. |
| US08735391B2 |
Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods
A functionalized polycyclic compound can have a structure of Formula 1 or salt, prodrug, analog, or derivative thereof, which compound can be prepared by providing a diene; reacting the diene with a dienophile under sufficient conditions for a combined Diels-Alder/acylation reaction so as to provide a polycyclic compound having a carboxylic acid; and coupling the carboxylic acid with an amine-containing compound or a hydroxyl-containing compound so as to form an amide or an ester and producing a compound having a structure of Formula 1. The compound can be used for modulating an opioid receptor, which can be conducted by administering to an opioid receptor a functionalized polycyclic compound as described herein in an effective amount to modulate the functionality of the opioid receptor. Such opioid modulation can provide a biological benefit to a subject. |
| US08735390B2 |
Polymorphs and salts
The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity. |
| US08735377B1 |
Methods of treating herpes zoster
A method of treating shingles in a human in need thereof. The method comprises administering a tetracycline compound in an amount that is effective to treat shingles, but has substantially no antibacterial activity. |
| US08735375B2 |
Therapeutic compositions
Ingenol angelate is a potent anticancer agent, and can be stabilized by dissolving it in an aprotic solvent in the presence of an acidic buffer. |
| US08735372B2 |
Nucleoside phosphoramidate prodrugs
Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure: Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I. |
| US08735369B2 |
Compositions and methods for inhibiting expression of a gene from the Ebola virus
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus. |
| US08735366B2 |
Pre-MRNA trans-splicing molecule (RTM) molecules and their uses
The present invention relates to specific and markedly improved pre-mRNA trans-splicing molecule (RTM) molecules which are designed to correct specific genes expressed within cells to be targeted, and which are associated with epidermolysis bullosa, cystic fibrosis, pachyonychia congenital, and psoriasis or neurodermitis, as well as cancers of the skin. In particular, the RTMs of the present invention are genetically engineered to interact with a specific target pre-mRNA expressed in cells to be targeted so as to result in correction of genetic defects or reprogramming of gene expression responsible for a variety of different skin disorders. |
| US08735365B2 |
Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. |
| US08735361B2 |
C1ORF59 peptides and vaccines including the same
The present invention provides isolated peptides having the amino acid sequence of SEQ ID NO: 43 or immunologically active fragments thereof, which bind to HLA antigen and have cytotoxic T lymphocyte (CTL) inducibility. The present invention further provides peptides which include one, two, or several amino acid insertions, substitution or addition to the aforementioned peptides or fragments, but still have the cytotoxic T cell inducibility. Further provided are nucleic acids encoding any of these aforementioned peptides as well as pharmaceutical agents and compositions including any of the aforementioned peptides or nucleic acids. The peptides, nucleic acids, pharmaceutical agents and compositions of this invention may be used for treating cancer or tumor. |
| US08735359B2 |
Combinations of modalities for the treatment of diabetes
A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus by administering an effective amount of a fusion protein composition comprising a T-cell co-stimulation antagonist and a portion of an immunoglobulin molecule and an effective amount of a Type 1 diabetes autoantigen. The method includes, for example, administering a cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) molecule and a Type 1 diabetes autoantigen. Pharmaceutical compositions are also provided herewith. |
| US08735353B2 |
Polypeptides and uses thereof
The present invention provides polypeptides comprising or consisting of an amino acid sequence from thrombin, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof, for use in the treatment or prevention of inflammation and/or excessive coagulation of the blood. Related aspects of the invention provide isolated polypeptides comprising or consisting of an amino acid sequence of any one of SEQ ID NOs: 1 to 7, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof, which exhibit an anti-inflammatory activity, together with isolated nucleic acid molecules, vectors and host cells for making the same. Additionally provided are pharmaceutical compositions comprising a polypeptide of the invention, as well as methods of use of the same in the treatment and/or prevention of inflammation and/or excessive coagulation. |
| US08735351B2 |
Phospholipid-enriched vesicles bearing tissue factor having haemostatic activities and uses thereof
The invention relates to a method for improving the procoagulant properties of TF expressed in eukaryotic cells by contacting microvesicles derived from said eukaryotic cells with a negatively-charged phospholipid such as phosphatidylserine. The invention also relates to microvesicles obtained using said method as well as to the uses thereof as procoagulant agents, for wound healing and for promoting angiogenesis. |
| US08735348B2 |
Casein derived peptides and uses thereof
Biologically active peptides that are derived from or are similar to sequences identical with the N-terminus of the αS1 fraction of milk casein. These peptides are capable of stimulating and enhancing immune response, protecting against viral infection, normalizing serum cholesterol levels, and stimulating hematopoiesis. The casein-derived peptides are non-toxic and can be used to treat and prevent immune pathologies, hypercholesterolemia, hematological disorders and viral-related diseases, alone or in combination with other peptides or blood cell stimulating factors. |
| US08735340B2 |
Conjugates that contain the homeodomain of antennapedia
The subject invention pertains to a conjugate comprising: (a) a first region comprising the homeodomain of antennapedia or a variant thereof; and (b) a second region not naturally associated with the first region. In one embodiment, the second region of the conjugate comprises a protein of at least 100 amino acids. |
| US08735337B2 |
Aqueous ozone solution for ozone cleaning system
A method of making an aqueous ozone solution for an industrial cleaning system is described. The method includes providing a reaction vessel for entraining ozone gas in an aqueous solution. The reaction vessel includes a conical-shaped surface having a two or more edges or ridges. The conical-shaped surface defines an interior, and two or more edges or ridges are in contact with the interior. The reaction vessel is in fluidic communication with a supply of water. The reaction vessel is in fluidic communication with a supply of a first aqueous ozone solution. The first aqueous ozone solution is directed to the conical-shaped surface. Water is directed to the conical-shaped surface, and the water and the first aqueous ozone solution are mixed to form a second aqueous ozone solution. |
| US08735336B1 |
Eco-friendly cleaners for oilfield equipment
Methods for removing an organic material from a portion of oilfield equipment are described. The methods include forming a composition that includes a hybrid polymer and introducing the composition to the portion of the oilfield equipment from which the organic material is to be removed. The hybrid polymer includes a synthetic component formed from at least one or more olefinically unsaturated carboxylic acid monomers or salts thereof, and a natural component formed from a hydroxyl-containing natural moiety. |
| US08735330B2 |
pVII phage display
The present invention provides an alternative scaffold for peptides displayed on filamentous phages through novel fusion proteins primarily originating from pVII. Libraries of filamentous phages can be created from fusion proteins, and a phage display system comprising a phagemid and a helper phage is a part of the invention. An aspect of the invention is a kit containing a phage display system comprising a phagemid and a helper phage that contains a nucleic acid encoding the fusion protein of the invention. |
| US08735328B2 |
Fusion polypeptide for detection of conserved combinatorial or composite epitopes in non-conserved proteins
The present invention provides multiepitope-binding fusion polypeptides for use in a method for the detection of the presence of human immunodeficiency virus, HIV, in a biological sample. The present invention also provides a method for producing multiepitope-binding fusion polypeptides. |
| US08735324B2 |
Esteramide solvents/coalescing agents in phytosanitary, cleaning, degreasing, stripping, lubricating, coating, and pigment/ink compositions
Esteramide compounds are useful solvents/coalescing agents for a variety of phytosanitary, cleaning, degreasing, stripping, lubricating, coating and pigment/ink compositions. |
| US08735320B2 |
Method of transfer printing using white toner
A novel method of transfer printing onto articles, particularly dark articles, is disclosed. A design, preferably in color, is printed onto a transfer sheet in sublimation dye using a commercially-available printer. White toner is then printed over at least a portion of the design using an electrostatic printing device. Heat and pressure are applied to transfer the design and the white toner to an article. In some preferred embodiments, the transfer sheet is a self-weeding transfer paper. In some preferred embodiments, the same printer is used to print both the sublimation dye design and the white toner. In some preferred embodiments, the color palette of the image is inverted prior to printing with white toner. The invention is particularly well suited to the transfer printing of dark textile articles. |
| US08735319B2 |
Metal contaminant removal compositions and methods for making and using the same
Metal sorbent compositions for removing a metal contaminant from a fluid, such as removal of mercury from a coal-fired flue gas stream, and methods for making and using the same are provided. The subject metal sorbent compositions comprise an effective amount of an aqueous dispersion of microfine elemental sulfur particles on an adsorbent substrate, and optionally, a metal capture enhancing agent such as a halogen source and/or an oxidizing agent in an amount providing a metal capture enhancing effect on the metal sorbent composition. The subject metal sorbent compositions are prepared by drying an aqueous dispersion of microfine elemental sulfur particles on an adsorbent substrate, such as on a substrate of microfine particles of a refractory material and the like. Also provided are kits for use in preparing the subject compositions, and compositions produced by the methods. The subject compositions, kits and systems find use in a variety of different applications. |
| US08735314B2 |
Catalysts for producing acrylic acids and acrylates
In one embodiment, the invention is to a catalyst composition comprising vanadium and titanium. The catalyst composition further comprises ethylene glycol and citric acid. Preferably, the catalyst composition is substantially free of oxalic acid and lactic acid. |
| US08735313B2 |
High charge density structures, including carbon-based nanostructures and applications thereof
The present invention generally provides compositions including carbon-based nanostructures, catalyst materials and systems, and related methods. In some cases, the present invention relates to carbon-based nanostructures comprising a high density of charged moieties. Methods of the invention may provide the ability to introduce a wide range of charged moieties to carbon-based nanostructures. The present invention may provide a facile and modular approach to synthesizing molecules that may be useful in various applications including sensors, catalysts, and electrodes. |
| US08735312B2 |
Catalyst composition and process for preparing olefin polymer using the same
The present invention relates to a catalyst composition and a process for preparing an olefin polymer using the same. More specifically, the present invention relates to a novel catalyst composition comprising at least two types of catalysts and a process for preparing an olefin polymer having excellent heat resistance using the same. The present invention can provide an olefin polymer having excellent activity and high heat resistance, and also can control the values of density, heat resistance and melt index (MI) of the olefin polymer. |
| US08735311B2 |
Copper CHA zeolite catalysts
Zeolite catalysts and systems and methods for preparing and using zeolite catalysts having the CHA crystal structure are disclosed. The catalysts can be used to remove nitrogen oxides from a gaseous medium across a broad temperature range and exhibit hydrothermal stable at high reaction temperatures. The zeolite catalysts include a zeolite carrier having a silica to alumina ratio from about 15:1 to about 256:1 and a copper to alumina ratio from about 0.25:1 to about 1:1. |
| US08735308B2 |
Optical member comprising TiO2-containing silica glass
The present invention relates to an optical member including a TiO2-containing silica glass having: a TiO2 concentration of from 3 to 10% by mass; a Ti3+ concentration of 100 wt ppm or less; a thermal expansion coefficient at from 0 to 100° C., CTE0-100, of 0±150 ppb/° C.; and an internal transmittance in the wavelength range of 400 to 700 nm per a thickness of 1 mm, T400-700, of 80% or more, in which the optical member has a ratio of variation of Ti3+ concentration to an average value of the Ti3+ concentration, ΔTi3+/Ti3+, on an optical use surface, is 0.2 or less. |
| US08735302B2 |
High productivity combinatorial oxide terracing and PVD/ALD metal deposition combined with lithography for gate work function extraction
Metal gate high-k capacitor structures with lithography patterning are used to extract gate work function using a combinatorial workflow. Oxide terracing, together with high productivity combinatorial process flow for metal deposition can provide optimum high-k gate dielectric and metal gate solutions for high performance logic transistors. The high productivity combinatorial technique can provide an evaluation of effective work function for given high-k dielectric metal gate stacks for PMOS and NMOS transistors, which is critical in identifying and selecting the right materials. |
| US08735299B2 |
Semiconductor device manufacturing method and computer-readable storage medium
There is provided a semiconductor device manufacturing method for forming a step-shaped structure in a substrate by etching the substrate having thereon a multilayer film and a photoresist film on the multilayer film and serving as an etching mask. The multilayer film is formed by alternately layering a first film having a first permittivity and a second film having a second permittivity different from the first permittivity. The method includes a first process for plasma-etching the first film by using the photoresist film as a mask; a second process for exposing the photoresist film to hydrogen-containing plasma; a third process for trimming the photoresist film; and a fourth process for etching the second film by using the trimmed photoresist film and the plasma-etched first film as a mask. The step-shaped structure is formed in the multilayer film by repeatedly performing the first process to the fourth process in this sequence. |
| US08735298B2 |
Method for spatial and temporal control of temperature on a substrate
An apparatus for control of a temperature of a substrate has a temperature-controlled base, a heater, a metal plate, a layer of dielectric material. The heater is thermally coupled to an underside of the metal plate while being electrically insulated from the metal plate. A first layer of adhesive material bonds the metal plate and the heater to the top surface of the temperature controlled base. This adhesive layer is mechanically flexible, and possesses physical properties designed to balance the thermal energy of the heaters and an external process to provide a desired temperature pattern on the surface of the apparatus. A second layer of adhesive material bonds the layer of dielectric material to a top surface of the metal plate. This second adhesive layer possesses physical properties designed to transfer the desired temperature pattern to the surface of the apparatus. The layer of dielectric material forms an electrostatic clamping mechanism and supports the substrate. |
| US08735290B2 |
Amorphous group III-V semiconductor material and preparation thereof
A reactive evaporation method for forming a group III-V amorphous material attached to a substrate includes subjecting the substrate to an ambient pressure of no greater than 0.01 Pa, and introducing active group-V matter to the surface of the substrate at a working pressure of between 0.05 Pa and 2.5 Pa, and group III metal vapor, until an amorphous group III-V material layer is formed on the surface. |
| US08735287B2 |
Semiconductor packaging process using through silicon vias
A microelectronic unit can include a semiconductor element having a front surface, a microelectronic semiconductor device adjacent to the front surface, contacts at the front surface and a rear surface remote from the front surface. The semiconductor element can have through holes extending from the rear surface through the semiconductor element and through the contacts. A dielectric layer can line the through holes. A conductive layer may overlie the dielectric layer within the through holes. The conductive layer can conductively interconnect the contacts with unit contacts. |
| US08735286B2 |
Deposition-free sealing for micro- and nano-fabrication
A method for sealing through-holes in a material via material diffusion, without the deposition of a sealant material, is disclosed. The method is well suited to the fabrication and packaging of microsystems technology-based devices and systems. In some embodiments, the method comprises forming sacrificial material release through-holes through a structural layer, removing the sacrificial material via an etch that etches the sacrificial material through the release through-holes, and sealing of the release through-holes via material diffusion. |
| US08735284B2 |
Conductive metal and diffusion barrier seed compositions, and methods of use in semiconductor and interlevel dielectric substrates
A metal seed composition useful in seeding a metal diffusion barrier or conductive metal layer on a semiconductor or dielectric substrate, the composition comprising: a nanoscopic metal component that includes a metal useful as a metal diffusion barrier or conductive metal; an adhesive component for attaching said nanoscopic metal component on said semiconductor or dielectric substrate; and a linker component that links said nanoscopic metal component with said adhesive component. Semiconductor and dielectric substrates coated with the seed compositions, as well as methods for depositing the seed compositions, are also described. |
| US08735281B2 |
Inter connection structure including copper pad and pad barrier layer, semiconductor device and electronic apparatus including the same
A semiconductor device including an interconnection structure including a copper pad, a pad barrier layer and a metal redistribution layer, an interconnection structure thereof and methods of fabricating the same are provided. The semiconductor device includes a copper pad disposed on a first layer, a pad barrier layer including titanium disposed on the copper pad, an inorganic insulating layer disposed on the pad barrier layer, a buffer layer disposed on the inorganic insulating layer, wherein the inorganic insulating layer and the buffer layer expose a portion of the pad barrier layer, a seed metal layer disposed on the exposed buffer layer, a metal redistribution layer disposed on the seed metal layer, and a first protective layer disposed on the metal redistribution layer. |
| US08735278B2 |
Copper etch scheme for copper interconnect structure
The present disclosure is directed to a method of manufacturing an interconnect structure in which a low-k dielectric layer is formed over a semiconductor substrate followed by formation of a copper or copper alloy layer over the low-k dielectric layer. The copper or copper alloy layer is patterned and etched to form a copper body having recesses, which are then filled with a low-k dielectric material. The method allows for formation of a damascene structures without encountering the various problems presented by non-planar features and by porus low-K dielectric damage. |
| US08735276B2 |
Semiconductor packages and methods of manufacturing the same
Provided are semiconductor packages and methods of manufacturing the semiconductor package. The semiconductor packages may include a substrate including a chip pad, a redistributed line which is electrically connected to the chip pad and includes an opening. The semiconductor packages may also include an external terminal connection portion, and an external terminal connection pad which is disposed at an opening and electrically connected to the redistributed line. The present general inventive concept can solve the problem where an ingredient of gold included in a redistributed line may be prevented from being diffused into an adjacent bump pad to form a void or an undesired intermetallic compound. In a chip on chip structure, a plurality of bumps of a lower chip are connected to an upper chip to improve reliability, diversity and functionality of the chip on chip structure. |
| US08735271B2 |
Gate tunable tunnel diode
A gate tunable diode is provided. The gate tunable diode includes a gate dielectric formed on a gate electrode and a graphene electrode formed on the gate dielectric. Also, the gate tunable diode includes a tunnel dielectric formed on the graphene electrode and a tunnel electrode formed on the tunnel dielectric. |
| US08735270B2 |
Method for making high-K metal gate electrode structures by separate removal of placeholder materials
In a replacement gate approach, a superior cross-sectional shape of the gate opening may be achieved by performing a material erosion process in an intermediate state of removing the placeholder material. Consequently, the remaining portion of the placeholder material may efficiently protect the underlying sensitive materials, such as a high-k dielectric material, when performing the corner rounding process sequence. |
| US08735268B2 |
Method for fabricating metal-oxide-semiconductor field-effect transistor
A method for fabricating a metal-oxide-semiconductor field-effect transistor includes the following steps. Firstly, a substrate is provided. A gate structure, a first spacer, a second spacer and a source/drain structure are formed over the substrate. The second spacer includes an inner layer and an outer layer. Then, a thinning process is performed to reduce the thickness of the second spacer, thereby retaining the inner layer of the second spacer. After a stress film is formed on the inner layer of the second spacer and the source/drain structure, an annealing process is performed. Afterwards, the stress film is removed. |
| US08735265B2 |
Methods of selectively forming silicon-on-insulator structures using selective expitaxial growth process
A method of forming a silicon based optical waveguide can include forming a silicon-on-insulator structure including a non-crystalline silicon portion and a single crystalline silicon portion of an active silicon layer in the structure. The non-crystalline silicon portion can be replaced with an amorphous silicon portion and maintaining the single crystalline silicon portion and the amorphous portion can be crystallized using the single crystalline silicon portion as a seed to form a laterally grown single crystalline silicon portion including the amorphous and single crystalline silicon portions. |
| US08735263B2 |
Method for manufacturing SOI substrate
An SOI substrate is manufactured by the following steps: a semiconductor substrate is irradiated with an ion beam in which the proportion of H2O+ to hydrogen ions (H3+) is lower than or equal to 3%, preferably lower than or equal to 0.3%, whereby an embrittled region is formed in the semiconductor substrate; a surface of the semiconductor substrate and a surface of a base substrate are disposed so as to be in contact with each other, whereby the semiconductor substrate and the base substrate are bonded; and a semiconductor layer is separated along the embrittled region from the semiconductor substrate which is bonded to the base substrate by heating the semiconductor substrate and the base substrate, so that the semiconductor layer is formed over the base substrate. |
| US08735262B2 |
Semiconductor device having a through contact and a manufacturing method therefor
According to an embodiment, a method of forming a semiconductor device includes: providing a wafer having a semiconductor substrate with a first side a second side opposite the first side, and a dielectric region arranged on the first side; mounting the wafer with the first side on a carrier system; etching a deep vertical trench from the second side through the semiconductor substrate to the dielectric region, thereby insulating a mesa region from the remaining semiconductor substrate; and filling the deep vertical trench with a dielectric material. |
| US08735260B2 |
Method to prevent metal pad damage in wafer level package
The present disclosure provide a method of manufacturing a microelectronic device. The method includes forming a bonding pad on a first substrate; forming wiring pads on the first substrate; forming a protection material layer on the first substrate, on sidewalls and top surfaces of the wiring pads, and on sidewalls of the bonding pad, such that a top surface of the bonding pad is at least partially exposed; bonding the first substrate to a second substrate through the bonding pad; opening the second substrate to expose the wiring pads; and removing the protection material layer. |
| US08735259B2 |
Method of producing insulation trenches in a semiconductor on insulator substrate
A method for producing one or plural trenches in a device comprising a substrate of the semiconductor on insulator type formed by a semiconductive support layer, an insulating layer resting on the support layer and a semiconductive layer resting on said insulating layer, the method comprising steps of: a) localised doping of a given portion of said insulating layer through an opening in a masking layer resting on the fine semiconductive layer, b) selective removal of said given doped area at the bottom of said opening. |
| US08735257B2 |
MOS varactor optimized layout and methods
Apparatus and methods for a MOS varactor structure are disclosed. An apparatus is provided, comprising an active area defined in a portion of a semiconductor substrate; a doped well region in the active area extending into the semiconductor substrate; at least two gate structures disposed in parallel over the doped well region; source and drain regions disposed in the well region formed on opposing sides of the gate structures; a gate connector formed in a first metal layer overlying the at least two gate structures and electrically coupling the at least two gate structures; source and drain connectors formed in a second metal layer and electrically coupled to the source and drain regions; and interlevel dielectric material separating the source and drain connectors in the second metal layer from the gate connector formed in the first metal layer. Methods for forming the structure are disclosed. |
| US08735256B1 |
Current-confined heterojunction bipolar transistor
A process, machine, manufacture, composition of matter, and improvement thereof, and method of making and method of using the same, as well as necessary intermediates, generally relating to the field of semiconductor devices, the structure of transistors, and the structure of compound semiconductor heterojunction bipolar transistors. |
| US08735255B2 |
Method of manufacturing semiconductor device
In a method of manufacturing a semiconductor device, a source/drain feature is formed over a substrate. A Si-containing layer is formed over the source/drain feature. A metal layer is formed over the Si-containing layer. A metal silicide layer is formed from the metal layer and Si in the Si-containing layer. |
| US08735251B2 |
Through silicon via and method of fabricating same
A through silicon via structure and a method of fabricating the through silicon via. The method includes: (a) forming a trench in a silicon substrate, the trench open to a top surface of the substrate; (b) forming a silicon dioxide layer on sidewalls of the trench, the silicon dioxide layer not filling the trench; (c) filling remaining space in the trench with polysilicon; after (c), (d) fabricating at least a portion of a CMOS device in the substrate; (e) removing the polysilicon from the trench, the dielectric layer remaining on the sidewalls of the trench; (f) re-filling the trench with an electrically conductive core; and after (f), (g) forming one or more wiring layers over the top surface of the substrate, a wire of a wiring level of the one or more wiring levels closest to the substrate contacting a top surface of the conductive core. |
| US08735250B2 |
Methods of forming gates of semiconductor devices
Methods of forming gates of semiconductor devices are provided. The methods may include forming a first recess in a first substrate region having a first conductivity type and forming a second recess in a second substrate region having a second conductivity type. The methods may also include forming a high-k layer in the first and second recesses. The methods may further include providing a first metal on the high-k layer in the first and second substrate regions, the first metal being provided within the second recess. The methods may additionally include removing at least portions of the first metal from the second recess while protecting materials within the first recess from removal. The methods may also include, after removing at least portions of the first metal from the second recess, providing a second metal within the second recess. |
| US08735249B2 |
Trenched power semiconductor device and fabrication method thereof
A trenched power semiconductor device on a lightly doped substrate is provided. Firstly, a plurality of trenches including at least a gate trench and a contact window are formed on the lightly doped substrate. Then, at least two trench-bottom heavily doped regions are formed at the bottoms of the trenches. These trench-bottom heavily doped regions are then expanded to connect with each other by using thermal diffusion process so as to form a conductive path. Afterward, the gate structure and the well are formed above the trench-bottom heavily doped regions, and then a conductive structure is formed in the contact window to electrically connect the trench-bottom heavily doped regions to an electrode. |
| US08735247B2 |
Method for fabricating nonvolatile memory device
A method for fabricating a nonvolatile memory device is disclosed. The method includes forming a first structure for a common source line on a semiconductor substrate, the first structure extending along a first direction, forming a mold structure by alternately stacking a plurality of sacrificial layers and a plurality of insulating layers on the semiconductor substrate, forming a plurality of openings in the mold structure exposing a portion of the first structure, and forming a first memory cell string at a first side of the first structure and a second memory cell string at a second, opposite side of the first structure. The plurality of openings include a first through-hole and a second through-hole, each through-hole passing through the plurality of sacrificial layers and plurality of insulating layers, and the first through-hole and the second through-hole overlap each other in the first direction. |
| US08735241B1 |
Semiconductor device structure and methods for forming a CMOS integrated circuit structure
Methods for forming CMOS integrated circuit structures are provided, the methods comprising performing a first implantation process for performing at least one of a halo implantation and a source and drain extension implantation into a region of a semiconductor substrate and then forming a stressor region in another region of the semiconductor substrate. Furthermore, a semiconductor device structure is provided, the structure comprising a stressor region embedded into a semiconductor substrate adjacent to a gate structure, the embedded stressor region having a surface differing along a normal direction of the surface from an interface by less than about 8 nm, wherein the interface is formed between the gate structure and the substrate. |
| US08735238B2 |
Method of fabricating a semiconductor device including high voltage and low voltage MOS devices
Methods and devices for forming both high-voltage and low-voltage transistors on a common substrate using a reduced number of processing steps are disclosed. An exemplary method includes forming at least a first high-voltage transistor well and a first low-voltage transistor well on a common substrate separated by an isolation structure extending a first depth into the substrate, using a first mask and first implantation process to simultaneously implant a doping material of a first conductivity type into a channel region of the low-voltage transistor well and a drain region for the high-voltage transistor well. |
| US08735233B2 |
Manufacturing method for thin film semiconductor device, manufacturing method for thin film semiconductor array substrate, method of forming crystalline silicon thin film, and apparatus for forming crystalline silicon thin film
A crystalline silicon thin film is formed by irradiating a silicon thin film with a laser beam. The laser beam is a continuous wave laser beam. An intensity distribution of the laser beam in a first region about a center of the intensity distribution is symmetric on an anterior side and a posterior side of the center. The intensity distribution in a second region about the center is asymmetric on the anterior side and the posterior side. The first region is from the maximum intensity of the laser beam at the center to an intensity half of the maximum intensity. The second region is at most equal to the half of the maximum intensity of the laser beam. In the second region, an integral intensity value on the posterior side is larger than on the anterior side. |
| US08735231B2 |
Manufacturing method of dual-gate thin film transistor
A dual-gate transistor including: a first insulating layer provided to cover a first conductive layer; a first semiconductor layer over the first insulating layer; second semiconductor layers over the first semiconductor layer, the second semiconductor layers are spaced from each other to expose the first semiconductor layer; impurity semiconductor layers over the second semiconductor layers; second conductive layers over the impurity semiconductor layers; second insulating layers over the second conductive layers; a third insulating layer to cover the first semiconductor layer, the second semiconductor layers, the impurity semiconductor layers, the second conductive layers, and the second insulating layers; and a third conductive layer at least over the third insulating layer, and in the dual-gate transistor including the first to third insulating layers with openings, the first insulating layer is substantially equal in thickness to the second insulating layer. |
| US08735230B2 |
Method for manufacturing a semiconductor device including an impurity-doped silicon film
A process for manufacturing a semiconductor device consecutively includes forming a recess in the surface region of a silicon substrate, forming a gate insulation film on the surface of the recess, depositing a silicon electrode film including an oxygen-mixed layer extending parallel to the surface of the recess, injecting impurities into silicon the electrode film 17, and heat-treating the silicon electrode film to diffuse impurities. |
| US08735219B2 |
Heterogeneous annealing method and device
A method of integrating a first substrate having a first surface with a first insulating material and a first contact structure with a second substrate having a second surface with a second insulating material and a second contact structure. The first insulating material is directly bonded to the second insulating material. A portion of the first substrate is removed to leave a remaining portion. A third substrate having a coefficient of thermal expansion (CTE) substantially the same as a CTE of the first substrate is bonded to the remaining portion. The bonded substrates are heated to facilitate electrical contact between the first and second contact structures. The third substrate is removed after heating to provided a bonded structure with reliable electrical contacts. |
| US08735216B2 |
Memory cell constructions, and methods for fabricating memory cell constructions
Some embodiments include methods for fabricating memory cell constructions. A memory cell may be formed to have a programmable material directly against a material having a different coefficient of expansion than the programmable material. A retaining shell may be formed adjacent the programmable material. The memory cell may be thermally processed to increase a temperature of the memory cell to at least about 300° C., causing thermally-induced stress within the memory cell. The retaining shell may provide a stress which substantially balances the thermally-induced stress. Some embodiments include memory cell constructions. The constructions may include programmable material directly against silicon nitride that has an internal stress of less than or equal to about 200 megapascals. The constructions may also include a retaining shell silicon nitride that has an internal stress of at least about 500 megapascals. |
| US08735209B2 |
Graphene device including a PVA layer or formed using a PVA layer
An apparatus or method can include forming a graphene layer including a working surface, forming a polyvinyl alcohol (PVA) layer upon the working surface of the graphene layer, and forming a dielectric layer upon the PVA layer. In an example, the PVA layer can be activated and the dielectric layer can be deposited on an activated portion of the PVA layer. In an example, an electronic device can include such apparatus, such as included as a portion of graphene field-effect transistor (GFET), or one or more other devices. |
| US08735200B2 |
Fabrication of robust electrothermal MEMS with fast thermal response
Embodiments of the invention provide robust electrothermal MEMS with fast thermal response. In one embodiment, an electrothermal bimorph actuator is fabricated using aluminum as one bimorph layer and tungsten as the second bimorph layer. The heating element can be the aluminum or the tungsten, or a combination of aluminum and tungsten, thereby providing a resistive heater and reducing deposition steps. Polyimide can be used for thermal isolation of the bimorph actuator and the substrate. For MEMS micromirror designs, the polyimide can also be used for thermal isolation between the bimorph actuator and the micromirror. |
| US08735199B2 |
Methods for fabricating MEMS structures by etching sacrificial features embedded in glass
In an embodiment a method of fabricating a MEMS structure is provided. The method includes fabricating a working structure in a doped layer proximate a first surface of a silicon substrate. The first surface of the silicon substrate is bonded to a first planar glass structure having a first one or more sacrificial features embedded therein. The method also includes etching to remove a bulk of the silicon substrate, wherein the bulk is reverse of the first surface on the silicon substrate, wherein etching removes the bulk and leaves the working structure bonded to the first planar glass structure. The method also includes etching to remove the first one or more sacrificial features from the first planar glass structure. |
| US08735197B2 |
Wafer-scaled light-emitting structure
This invention discloses a wafer-scaled light-emitting structure comprising a supportive substrate; an anti-deforming layer; a bonding layer; and a light-emitting stacked layer, wherein the anti-deforming layer reduces or removes the deformation like warp caused by thinning of the substrate. |
| US08735196B2 |
Method of manufacturing nitride semiconductor light emitting device
According to one embodiment, in a method of a nitride semiconductor light emitting device, a nitride semiconductor laminated body is formed on a first substrate having a first size. A first adhesion layer with a second size smaller than the first size is formed on the nitride semiconductor laminated body. A second adhesion layer is formed on a second substrate. The first and the second substrates are bonded while the first and second adhesion layers being overlapped each other. The first substrate is removed so as to generate a recess having a third size equal to or larger than the second size. The first substrate is etched until exposing the nitride semiconductor laminated body while injecting a chemical solution into the recess. The exposed nitride semiconductor laminated body is etched using the chemical solution so as to form a concave-convex portion in the exposed nitride semiconductor laminated body. |
| US08735187B2 |
Array substrate for reflective type or transflective type liquid crystal display device and method of fabricating the same
An array substrate for a liquid crystal display device includes a substrate, a gate line and a data line on the substrate and crossing each other to define a pixel region, a thin film transistor connected to the gate line and the data line, a first passivation layer on the thin film transistor and having a first unevenness structure at its top surface, an auxiliary unevenness layer on the first passivation layer and having a first roughness structure at its top surface, and a reflector on the auxiliary unevenness layer, the reflector having a second unevenness structure due to the first unevenness structure of the first passivation layer and a second roughness structure due to the first roughness structure of the auxiliary unevenness layer, the second roughness structure having smaller patterns than the second unevenness structure. |
| US08735186B2 |
Beam homogenizer, laser irradiation apparatus, and method for manufacturing semiconductor device
The energy distribution of the beam spot on the irradiated surface changes due to the change in the oscillation condition of the laser or before and after the maintenance. The present invention provides an optical system for forming a rectangular beam spot on an irradiated surface including a beam homogenizer for homogenizing the energy distribution of the rectangular beam spot on the irradiated surface in a direction of its long or short side. The beam homogenizer includes an optical element having a pair of reflection planes provided oppositely for reflecting the laser beam in the direction where the energy distribution is homogenized and having a curved shape in its entrance surface. The entrance surface of the optical element means a surface of the optical element where the laser beam is incident first. |
| US08735183B2 |
System in package (SIP) with dual laminate interposers
There is provided a semiconductor device assembly with an interposer and method of manufacturing the same. More specifically, in one embodiment, there is provided a semiconductor device assembly comprising a semiconductor substrate, at least one semiconductor die attached to the semiconductor substrate, an interposer disposed on the semiconductor die, and a controller attached to the interposer. There is also provided a method of manufacturing comprising forming a first subassembly by coupling a substrate and a semiconductor die, and forming second subassembly by attaching a controller to an interposer, and coupling the first subassembly to the second subassembly. |
| US08735182B2 |
Method for detecting embedded voids in a semiconductor substrate
A method for detecting embedded voids present in a structure formed in or on a semiconductor substrate is described. The method includes performing a processing step P1 for forming the structure; measuring the mass M1 of the substrate; performing thermal treatment; measuring the mass M2 of the substrate; calculating the mass difference between the mass of the substrate measured before and after the performed thermal treatment; and deducing the presence of embedded voids in the structure by comparing the mass difference with a pre-determined value. |
| US08735180B2 |
Multiple-points measurement
A stacking apparatus that stacks chip assemblies each having a plurality of chips disposed continuously with circuit patterns and electrodes, includes: a plurality of stages each allowed to move arbitrarily, on which the chip assemblies are placed; a storage unit that stores an estimated extent of change in a position of an electrode at each chip, expected to occur as heat is applied to the chip assemblies placed on the plurality of stages during a stacking process; and a control unit that sets positions of the plurality of stages to be assumed relative to each other during the stacking process based upon the estimated extent of change in the position of the electrode at each chip provided from the storage unit and position information indicating positions of individual chips formed at the chip assemblies and controls at least one of the plurality of stages. |
| US08735177B2 |
Diagnostic marker
A diagnostic marker is composed of particles that have a diameter of from 1 nm to 100 μm, the particles possessing on their surfaces a site that has a high specific bonding ability to a specific antigen residing on the mucosa of digestive cancers and a site that has a low bonding ability to the mucosa of digestive organs, and further incorporating an identification material. |
| US08735174B2 |
Coated colloidal materials
Coated colloidal materials, methods for making coated colloidal materials, and methods of using coated colloidal materials are disclosed. The method yields coated colloidal materials where the optical characteristics of the core is not adversely affected. The coated colloidal materials can be self-assembled into films, layers, or structures and used in the detection of analytes through detection assays. |
| US08735170B2 |
Method for measuring concentration of antigen contained in test solution
A biogenic substance concentration measuring apparatus includes an optical measuring apparatus for measuring optical properties of a first substrate and a second substrate by using a cell for biogenic substance concentration measurement that includes: the first substrate on which a plurality of first metallic nanorods, each of which is modified with a substance that bonds specifically to a test substance, are immobilized such that the long axes thereof are aligned in the same direction; and the second substrate on which a plurality of second metallic nanorods, each of which is modified with a blocking substance, are immobilized such that the long axes thereof are aligned perpendicularly to the long axes of the first metallic nanorods on the first substrate, and calculates a biogenic substance concentration with high accuracy from the optical properties. |
| US08735169B2 |
Methods for analyzing agricultural and environmental samples
The present invention generally relates methods for analyzing agricultural and/or environmental samples using liquid bridges. In certain embodiments, the invention provides a method for analyzing an agricultural sample for a desired trait including obtaining a gene or gene product from an agricultural sample, in which the gene or gene product is in a first fluid; providing a liquid bridge for mixing the gene or gene product with at least one reagent to form a mixed droplet that is wrapped in an immiscible second fluid; and analyzing the mixed droplet to detect a desired trait of the agricultural sample. |
| US08735168B2 |
Removing polypeptides from stool
This document provides methods and materials involved in removing polypeptides (e.g., high abundance polypeptides) from stool samples. For example, methods and materials for preparing a stool sample for detecting polypeptides of low abundance are provided. For example, this document provides methods and materials for depleting abundant polypeptides common to stool from normal, healthy humans from a stool sample. Such depleted stool samples can be used to detect polypeptides of interest such as low abundance polypeptides or neoplasm-specific polypeptide markers that can be present in a mammal suffering from a disease such as cancer. |
| US08735155B1 |
Compositions for regenerating defective or absent myocardium
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. |
| US08735152B2 |
Methods for inducing cell death in pluripotent stem cells and differentiated cells other than cardiac myocytes
The present invention has as its object developing a method that does not involve genomic modification and which yet is capable of inducing cell death in pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, as well as in differentiated cells other than cardiomyocytes derived from pluripotent stem cells, but not in cardiomyocytes. It has been revealed that by establishing a method capable of inducing cell death in cells other than cardiomyocytes in a very efficient manner by adding a substance having no recognized inherent toxicity or cell death inducing action to the culture conditions for pluripotent stem cells and non-cardiomyocytes, the stated problem can be solved without relying upon genomic modification. |
| US08735149B2 |
Motor neurons developed from stem cells
Provided is a method for directing differentiation of neural progenitors with a caudal and ventral specification into motor neurons including culturing neural progenitors in a culturing medium including a basic medium supplemented by at least one inhibitor of the Notch signaling pathway whereby the neural progenitors differentiate into postmitotic motor neurons. The resulting motor neurons may be used for drug development, as carriers, e.g. for gene therapy of protein delivery as well as for transplantation for the purpose of treating a motor neuron disease. |
| US08735146B2 |
Chimeric binding peptide library screening method
There is described a method of isolating nucleotide sequences encoding target peptides from DNA libraries using DNA binding proteins to link the peptide to the sequence which encodes it. DNA libraries are prepared from cells encoding the protein of interest, or from synthetic DNA, and inserted into, or adjacent to, a DNA binding protein in an expression vector to create a chimeric fusion protein. Incorporation of the vector DNA into a carrier package, during expression of the chimeric fusion protein, results in the production of a peptide display carrier package (PDCP) displaying the DNA-bound fusion protein on the external surface of the carrier package. Employment of affinity purification techniques results in the PDCP particles containing sequences encoding the desired peptide to be selected and the desired nucleotide sequences obtained therefrom. |
| US08735138B2 |
Non-recombinant Saccharomyces strains that grow on xylose
The present invention relates to methods for producing Saccharomyces strains that are capable of growth on xylose as a sole carbon source at a desired growth rate (such as at least one generation per 48 hours), strains made by such methods, and Saccharomyces strains that grow at a growth rate of at least one generation per 48 hours using xylose as a sole carbon source for growth made by non-recombinant methods. |
| US08735136B2 |
Biological culture of a strain of the Pseudomonas graminis species, use of said culture as antagonist for biological control of pathogenic bacteria, and method for treating fruit that comprises the step of applying, to the fruit, a preparation that comprises said culture
Substantially pure biological culture of a strain of the species Pseudomonas graminis, deposited with number CBS136973 at the depositary institution “Centraalbureau voor Schimmelcultures” (CBS) in Utrecht, Netherlands. Use of the CBS136973 culture as an antagonist for the biocontrol of foodborne pathogenic bacteria in fruit intended for human consumption. Method for treating the fruit which comprises the step of applying a preparation that comprises a culture of a strain of the species Pseudomonas graminis, deposited with number CBS136973 at the depositary institution “Centraalbureau voor Schimmelcultures” (CBS) in Utrecht, Netherlands, to the fruit. The application thereof makes it possible to reduce the growth of pathogens during the shelf life of the product, especially when the cold chain is broken. |
| US08735135B2 |
Transformed strains originated from multidrug efflux protein defective strains and a method for microbial conversion using them
Disclosed is a means for improving the poor conversion efficiency in a conventional bioconversion system using a transformant which is given by introducing a gene originated from xerogenic organisms. A transformant is prepared by using a host which is defective in a gene encoding a multidrug efflux protein and introducing a gene originated from xerogenic organisms. Use of the transformant results in much effective microbial conversion of a hydrophobic or amphipathic substrate compound into a desired compound. In case, an Escherichia coli is used as the host, the gene encoding a multidrug efflux protein to be defective may be tolC, acrA, acrB and the like. |
| US08735131B2 |
Method for designing mutant protein deamidase
An object is to provide a novel method for improving an enzyme capable of deamidating a protein. A mutant protein deamidase is designed by the following steps: (A) identifying one or more amino acid in an amino acid sequence for a protein deamidase which corresponds to the amino acid at position 35, 38 to 43, 45, 46, 49, 79 to 84, 103 to 106, 117, 142, 143, 146, 166, or 185 in the amino acid sequence set forth in SEQ ID NO: 2; and (B) constructing a mutant amino acid sequence of the protein deamidase by substituting the one or more amino acid identified in step (A) with another amino acid or other amino acids or by deleting the one or more amino acid identified in step (A). |
| US08735130B2 |
Polypeptides having glucoamylase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having glucoamylase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| US08735126B2 |
Disease control with tick phospholipase A2
The present invention relates to reagents and methods for the modulation of viability of bacteria. A process is provided wherein a protein sequence from A. americanum saliva effective in reducing the viability of gram positive, gram negative, or acid-fast bacteria and spirochetes including B. burgdurferi is administered. The inventive protein from A. americanum saliva has utility as a therapeutic for the treatment of an organism infected with bacteria, particularly the spirochete B. burgdorferi. |
| US08735121B2 |
DNA polymerases with increased 3′-match discrimination
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases. |
| US08735118B2 |
Xylanase composition with increased stability
A xylanase composition and a method for manufacturing the xylanase composition are provided, wherein the xylanase composition comprises a xylanase and a stabilizer, and the xylanase is from an anaerobic fungus, the stabilizer comprises a polyol, and the content of the polyol is at least 40 wt %, based on the total weight of the xylanase composition. |
| US08735114B2 |
Fermentive production of four carbon alcohols
Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway. |
| US08735111B2 |
Processes for producing hydrocarbon products
The present invention relates to processes for producing industrial products such as hydrocarbon products from non-polar lipids in a vegetative plant part. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels. |
| US08735106B2 |
Immobilization of psicose-epimerase and a method of producing D-psicose using the same
The present invention relates to a method of successively producing D-psicose from D-fructose or D-glucose by using a psicose-epimerase derived from Agrobacterium tumefaciens which is expressed in a food safety form. |
| US08735104B2 |
Direct nucleic acid analysis
Methods and apparatus are described for nucleic acid analysis of swab samples without the need for purification. |
| US08735102B2 |
Hyaluronan synthase genes and expression thereof in Bacillus hosts
The present invention relates to a recombinant Bacillus host cell containing a recombinant vector including a nucleic acid segment having a coding region segment encoding enzymatically active hyaluronan synthase (HAS). The recombinant Bacillus host cell is utilized in a method for producing hyaluronic acid (HA). |
| US08735100B2 |
Cellulose and ligno-cellulose active proteins
Methods to digest carbohydrates, especially lignocelluloses and hemicelluloses, using fungal proteins previously not recognized as having this activity are described. |
| US08735099B2 |
Melibiose operon expression system
New vectors expressible in a host comprising the promoter region of the melibiose operon operably linked to a transcriptional unit that includes nucleic acid sequence which is heterologous to the host. The expression of the nucleic acid sequence is controlled by the promoter region of the melibiose operon. The new vector can be used for the regulated heterologous expression of a nucleic acid sequence in a prokaryotic host. There is an isolated and purified nucleic acid sequence expressible in a host comprising the promoter region of the melibiose operon operably linked to a transcriptional unit that includes a nucleic acid sequence which is heterologous to the host. The expression of the nucleic acid sequence is controlled by the promoter region of the melibiose operon. A prokaryotic host is transformed with the vector or the isolated and purified nucleic acid sequence. There is a method for producing a polypeptide in a host using the vector. |
| US08735096B2 |
Optical control of protein activity and localization by fusion to photochromic protein domains
Engineered fusion proteins comprising photochromic protein domains are disclosed. In particular, the inventors have constructed fusion proteins containing photoswitchable photochromic fluorescent protein domains linked to selected proteins and shown that such fusion proteins can be used to control the activity or localization of selected proteins with light. |
| US08735095B2 |
High affinity human antibodies to human IL-4 receptor
The present invention provides nucleic acid molecules that encode antibodies or antigen-binding fragments thereof, which specifically bind human interleukin-4 receptor (IL-4R). Also provided are expression vectors comprising nucleic acid molecule that encode anti-IL-4R antibodies, host cells comprising the expression vectors, and methods of producing anti-IL-4R antibodies or antigen-binding fragments thereof comprising growing the host cells under conditions permitting production of the antibody or fragment, and recovering the antibody or fragment so produced. |
| US08735094B2 |
Yarrowia n-alkane-hydroxylating cytochrome P450 promoter regions for gene expression in yeast
Promoter regions associated with the Yarrowia lipolytica n-alkane-hydroxylating cytochrome P450 (ALK2) gene are disclosed and have been found to be particularly effective for the expression of heterologous genes in yeast. These promoter regions will be useful for driving high-level expression of genes involved in the production of omega-3 and omega-6 fatty acids. |
| US08735093B2 |
Mutant pyrrolysyl-tRNA synthetase, and method for production of protein having non-natural amino acid integrated therein by using the same
Method for incorporating a lysine derivative (particularly an Nε-benzyloxycarbonyl-lysine (Z-Lys) derivative) having useful functional group such as heavy atom, selenium, reactive functional group, fluorescent group or crosslinker, which is suitable as a non-natural amino acid, into a desired protein in a site-specific manner. A mutant pyrrolysyl-tRNA synthetase has substitution of at least one amino acid residue selected from tyrosine residue at position 306, leucine residue at position 309 and cysteine residue at position 348 each constituting a pyrrolysine-binding site in the amino acid sequence for pyrrolysyl-tRNA synthetase of SEQ ID NO:2. The substitution of the amino acid residue is: of tyrosine residue at position 306 by glycine or alanine residue, of leucine residue at position 309 by glycine or alanine residue, and/or of a cysteine residue at position 348 by valine, serine or alanine residue. |
| US08735091B2 |
Methods for inactivation and extraction of acid-fast bacteria for characterization and/or identification using mass spectrometry
The present invention is directed to a method for inactivation and/or extraction of acid-fast bacteria (e.g., mycobacteria or nocardia), the method comprising the following sequential steps: (a) acquiring a test sample known to contain or that may contain acid-fast bacteria and suspending the test sample in a container containing ethanol and beads; (b) bead beating and/or vortexing the container to break up clumps and/or disrupt acid-fast bacteria cells in the container; and (c) subsequently incubating the suspension for at least about 3 minutes at room temperature to inactivate any acid-fast bacteria contained in the test sample. In accordance with the present invention, the test sample can subsequently be pelleted by centrifugation, resuspended with formic acid, acetonitrile added, and subjected to mass spectrometry for characterization and/or identification of the acid-fast bacteria. |
| US08735089B2 |
Method for selecting bacteria with anti-oxidant action
The present invention relates to a method using Caenorhabditis elegans for screening of food grade bacteria which have a protective effect against oxidative stress. |
| US08735087B2 |
Use of alkaline phosphatase for preventing or reducing liver disease
The present invention provides a use for alkaline phosphatase for the manufacture of a medicament for the prevention or reduction of toxic LPS influx through a mucosal lining of a mammalian body cavity. A source of alkaline phosphatase is administered for the prophylaxis or treatment of LPS mediated or exacerbated diseases. The invention also provides compositions comprising a source of alkaline phosphatase for the prevention or reduction of (toxic) LPS influx or passage through mucosal layers. |
| US08735085B2 |
Method for diagnosing diseases using a protein or degradation product based on half-life
One aspect of the invention provides a method of diagnosing a disease condition, comprising measuring presence or amount of a targeted protein or a degradation product of said protein in a collected biological sample as a marker for the disease condition. The targeted protein or degradation product is selected for measurement based on a prior identification of a measurable half-life at a predetermined time period, including the time at which said method is conducted, and correlating said measuring with the presence or absence of the disease condition. The targeted protein or degradation product may be identified by selecting a protein known or suspected to be a diagnostic marker for the disease condition, analyzing degradation of the protein in the collected biological sample, and selecting a protein or degradation product that exhibits a measurable half-life at a predetermined period of time. The analyzing may include identifying degradation product(s) of the protein as a function of time, and half-life of the protein and the degradation product(s). |
| US08735083B2 |
Inhibition of peroxidase enzymatic activity
The present invention deals with reagents and compositions capable of effectively inhibiting peroxidase activity. According to the invention, peroxidase enzymatic activity is blocked with an acidic aqueous solution of a protein denaturing agent. preferred protein denaturing agents are detergents and chaotropic substances. |
| US08735080B2 |
Methods and devices for detecting obstructive uropathy and associated disorders
Methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described. |
| US08735078B2 |
Apolipoprotein AII assay method for the in vitro diagnosis of colorectal cancer
The present invention relates to a method for the in vitro diagnosis of colorectal cancer by determining the presence of the Apolipoprotein AII tumor marker in a biological sample taken from a patient suspected of having colorectal cancer. Said method can be used for early diagnosis, screening, therapeutic follow-up and prognosis, and also for relapse diagnosis in relation to colorectal cancer. |
| US08735076B2 |
Targets for use in diagnosis, prognosis and therapy of cancer
Provided herein are targets that can be used for the diagnosis, prognosis and therapy of a variety of cancers. |
| US08735075B2 |
Cancer screening by detection of ultrastructural and molecular markers
The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject. |
| US08735073B2 |
Cannabinoid 2 (CB2) receptor gene promoter and unique RNA transcripts in B cells and methods of use
Cannabinoid receptor 2 (CB2) is expressed in B lymphocytes and is involved in immune regulation. Mouse splenic B cells express three CB2 transcripts utilizing two different first exons. Human peripheral blood B cells express one CB2 transcript utilizing one first exon. Alignment of sequenced RACE products to either the mouse or human genome reveals that isolated transcripts contain previously unidentified transcriptional start sites (TSS). B cells from mouse and human preferentially express one transcript, exon 1a in mouse and exon 1 in human. Multiple CB2 TSSs are utilized in mouse splenic B cells and one TSS in human peripheral blood B cells. The defining of the receptor gene TSSs in these cells provides materials and methods for therapeutically regulating immune function, including antibody isotype switching, using compounds such as inhibitory nucleic acids that down-regulate expression of the B cell CB2 gene (e.g., RNAi molecules). |
| US08735067B2 |
Asymmetric PCR amplification, its special primer and application
The present invention discloses an asymmetric PCR amplification method, its special primer and application, aims to provide a simple, effective PCR amplification for preparation of single-stranded product. The asymmetric PCR primer of the invention comprises some PCR primer pairs, in which an unrelated nucleic acids sequence to target sequence to be detected is added onto 5′-terminal of one primer. The asymmetric PCR amplification provided includes the steps: 1) preparative denaturing; 2) repetitiously denaturing, primers annealing, extending cycles as the first stage of PCR amplification; 3) repetitiously denaturing, primer extending cycles as the second stage of PCR amplification, wherein an unrelated nucleic acids sequence to target sequence to be detected is added onto 5′-terminal of one PCR primer of each pair in extension. With the asymmetric PCR amplification of the invention, high throughput of single-stranded products can be obtained, single PCR amplification or multiple PCR amplification can be carried out. And the method can be widely used in detection of nucleic acids. |
| US08735066B2 |
Tumor suppressor designated TS10Q23.3
A specific region of chromosome 10 (10q23.3) has been implicated by series of studies to contain a tumor suppressor gene involved in gliomas, as well as a number of other human cancers. One gene within this region was identified, and the corresponding coding region of the gene represents a novel 47 kD protein. A domain of this product has an exact match to the conserved catalytic domain of protein tyrosine phosphatases, indicating a possible functional role in phosphorylation events. Sequence analyses demonstrated the a number of exons of the gene were deleted in tumor cell lines used to define the 10q23.3 region, leading to the classification of this gene as a tumor suppressor. Further analyses have demonstrated the presence of a number of mutations in the gene in both glioma and prostate carcinoma cells. Methods for diagnosing and treating cancers related to this tumor suppressor, designated as TS10q23.3, also are disclosed. |
| US08735064B2 |
Methods for creating and identifying functional RNA interference elements
The invention relates to the control of gene expression. Specifically, the invention provides compositions and methods for the production and use of recombinant nucleic acid molecules that have the ability to specifically downregulate an expressed target gene in vivo. In some aspects, the invention provides methods for producing a hairpin DNA molecule where part of the molecule is derived from an mRNA that is a target for a small interfering RNA (siRNA) derived from the hairpin. In other aspects, the invention provides synthetic hairpin adapter oligonucleotides that are used in the construction of siRNA-producing cassettes. In other aspects, the invention provides methods for testing for the presence or absence of specific inhibitory activity of an RNAi trigger molecule, and in still other aspects, the invention provides methods for identifying an active RNAi trigger molecule from a library of RNAi trigger molecules. In still other aspects, the invention provides methods for identifying a polynucleotide from a plurality of candidate target polynucleotides that is specifically targeted by an RNAi trigger molecule. In other aspects, the invention provides epi-allelic series of hypomorphic RNAi trigger molecules specific for any gene of interest, where the series of RNAi trigger molecules have a variety of uses including analysis of gene function and drug target development. |
| US08735063B2 |
Methods and reagents for genotyping HCV
The present invention is directed to methods and reagents for determining the genotype of a hepatitis C virus (HCV) species present in a test sample. The invention more particularly relates to mixtures of degenerate amplification and sequencing primers, and methods of using such primers, that are complementary to a plurality of HCV species, and are capable of generating nucleotide sequence information for a region of NS5B of HCV that is, for each species, indicative of the type and/or subtype, of the species present in the sample. |
| US08735061B2 |
Biomarkers of cancer metastasis
There is provided a method for determining tumour metastatic potential using biomarkers of tumour metastasis comprising any two of carbonic anhydrase-9 (CAIX), vascular endothelial growth factor C (VEGF-C), ephrin A5 (EFNA5), eph receptor B2 (EPHB2), transforming growth factor beta 3 (TGF-β3), pyruvate dehydrogenase kinase isoenzyme-3 (PDK3), carbonic anhydrase-12 (CAXII), keratin 14 (KRT14), hypoxia inducible factor 1 alpha subunit (HIF-1α), and tenascin C (TNC). CAIX, VEGF-C, EFNA5, EPHB2, TGF-β3 or PDK3 may be indicators of moderate metastatic potential, while CAXII, KRT14, HIF-1α, or TNC may be indicators of high metastatic potential. The biomarkers may be used to assess malignancies or cancers having hypoxic regions, such as breast cancer. |
| US08735060B2 |
Method for isolating high-purity RNA by means of paramagnetic microparticles and nanoparticles
The invention relates to a purification method for high-purity, DNA-free RNA using a mixture of nanocarrier beads and paramagnetic beads. |
| US08735059B2 |
Methods for determination of haplotype dissection
A method for molecular haplotyping of a subject is disclosed. The method comprises: randomly selecting a set of chromosomes in each of a plurality of lyzed diploid cells of the subject, collecting the selected chromosomes from said plurality of cells into a plurality of sample tubes, wherein each sample tube contains chromosomes selected from one or more cells, genotyping genomic DNA in each sample tube, and determining haplotype of the alleles based on allele nucleotide sequence information and corresponding nucleotide signal intensities from genotyping data. Other methods for molecular haplotyping using single cell lysate or single cell microdissection are also disclosed. |
| US08735058B2 |
ShRNA molecules and methods of use thereof
The present invention relates to certain novel shRNA molecules and methods of use thereof. According to certain embodiments of the present invention, methods for reducing the expression level of a target gene are provided. Such methods generally comprise providing a cell with one or more precursor nucleic acid sequences that encode two or more RNA molecules. A first RNA molecule comprises a double stranded sequence, which includes a guide strand sequence that is complementary to a portion of an mRNA transcript encoded by the target gene. In addition, a second RNA molecule comprises a second double stranded sequence, which includes a second guide strand sequence that is partially complementary to a portion of the mRNA transcript encoded by the target gene. Preferably, the second guide strand sequence comprises one or more bases that are mismatched with a nucleic acid sequence of the mRNA transcript encoded by the target gene. |
| US08735053B2 |
Methods of forming photoresist patterns
Methods of forming photoresist patterns may include forming a photoresist layer on a substrate, exposing the photoresist layer using an exposure mask, forming a preliminary pattern by developing the exposed photoresist layer and treating a surface of the preliminary pattern using a treatment agent that includes a coating polymer. |
| US08735052B2 |
Surface modifying material, method of forming resist pattern, and method of forming pattern
A surface modifying material for forming a surface modifying layer provided between a substrate and a resist film, the surface modifying material including an epoxy resin having a weight average molecular weight of 1,000 to 50,000; a method of forming a resist pattern, including: forming a surface modifying layer on a substrate using the surface modifying material, forming a resist film on the substrate, on which the surface modified layer has been formed, using a resist composition, conducting exposure of the resist film, and alkali developing the resist film to form a resist pattern; and a method of forming a pattern, including: etching the substrate, on which a resist pattern has been formed by the method of forming a resist pattern. |
| US08735051B2 |
Exposure method and exposure apparatus, and device manufacturing method
Exposure apparatus is equipped with an illumination optical device which illuminates a mask with an exposure beam, a mask table which holds a periphery of a pattern area of the mask from above so that a pattern surface of the mask becomes substantially parallel to an XY plane and makes a force at least parallel to an XY plane and on the mask, and a wafer stage which moves along the XY plane, holding a wafer substantially parallel to the XY plane. Therefore, an overlay with high precision of a pattern of a mask and an underlying pattern on the substrate can be realized, even though the exposure apparatus employs a proximity method, that is, the exposure apparatus does not use a projection optical system. |
| US08735042B2 |
Electrostatic latent image developing toner, developer, toner cartridge, process cartridge, image forming method, and image forming apparatus
An electrostatic latent image developing toner includes: a release agent; a pigment; and a binder resin. The content of the pigment is from about 10% by weight to about 50% by weight, the glass transition temperature (Tg) of the toner is in the range of from about −60° C. to about 20° C., and the Young's modulus at 20° C. is in the range of from about 1×100 MPa to about 1×103 MPa. |
| US08735038B2 |
Toner for non-contact fusing
A toner for non-contacting fusing containing toner matrix particles containing a resin binder and an external additive having an average particle size of from 10 to 100 nm, wherein the external additive is externally added to the toner matrix particles, wherein the resin binder contains one or more polyesters, wherein a carboxylic acid component of the polyester contains one or more isophthalic acid compounds and one or more fumaric acid/maleic acid compounds, wherein the isophthalic acid compound is contained in an amount of from 10 to 35% by weight, the fumaric acid/maleic acid compound is contained in an amount of from 1 to 15% by weight, and the isophthalic acid compound and the fumaric acid/maleic acid compound are contained in a total amount of from 20 to 36% by weight, of a total amount of the entire raw material monomers of the polyester in the resin binder, and wherein the toner has a softening point of from 90° to 120° C. The toner is suitably used in developing latent images formed in, for example, electrophotography, an electrostatic recording method, an electrostatic printing method, or the like. |
| US08735037B2 |
Toner, developer, process cartridge, image forming method, and image forming apparatus
A toner obtained by a method for producing a toner, which includes dissolving or dispersing in an organic solvent a toner material containing at least a binder resin, and a dispersion liquid of a crystalline polyester resin, so as to prepare a solution or dispersion liquid of the toner material, emulsifying or dispersing the solution or dispersion liquid of the toner material in an aqueous medium, so as to prepare an emulsion or dispersion liquid, and removing the organic solvent from the emulsion or dispersion liquid, wherein the crystalline polyester resin is localized near a surface of the toner. |
| US08735033B2 |
Toner process using acoustic mixer
A process for making emulsion aggregation (EA) toners is provided. In embodiments, the process comprises aggregating a mixture comprising a latex resin, and at least one colorant in a reactor to form aggregated toner particles, adding a shell resin to form a shell over the aggregated toner particles, coalescing the aggregated toner particles, and recovering the toner particles. |
| US08735027B2 |
Photosensitive resin composition for color filter and color filter using the same
Disclosed are a photosensitive resin composition for a color filter and a color filter using the same. The photosensitive resin composition for a color filter includes (A) a dye-polymer composite including a structural unit derived from a compound represented by the following Chemical Formula 1; (B) an acrylic-based photopolymerizable monomer; (C) a photopolymerization initiator; and (D) a solvent. In Chemical Formula 1, each substituent is the same as defined in the detailed description. |
| US08735016B2 |
Hydrophilic, electrically conductive fluid distribution plate for fuel cell
In at least one embodiment, the present invention provides a hydrophilic electrically conductive fluid distribution plate and a method of making, and system for using, the hydrophilic electrically conductive fluid distribution plate. In at least one embodiment, the plate comprises a plate body defining a set of fluid flow channels configured to distribute flow of a fluid across at least one side of the plate, and a composite conductive coating having a water contact angle of less than 40° adhered to the plate body. In at least one embodiment, the composite coating comprises a polymeric conductive layer adhered to the plate body having an exterior surface, and a particulate carbon layer adhered to the exterior surface of the polymeric conductive layer. |
| US08735013B1 |
Methods for fabricating inorganic proton-conducting coatings for fuel-cell membranes
The present invention provides methods for fabricating a fuel cell membrane structure that can dramatically reduce fuel crossover, thereby improving fuel cell efficiency and power output. Preferred composite membrane structures include an inorganic layer situated between the anode layer and the proton-exchange membrane. The inorganic layer can conduct protons in unhydrated form, rather than as hydronium ions, which reduces fuel crossover. Some methods of this invention include certain coating steps to effectively deposit an inorganic layer on an organic proton-exchange membrane. |
| US08735012B2 |
Direct oxidation fuel cell system with uniform vapor delivery of fuel
A fuel cell system which includes a fuel distribution structure that uniformly distributes vaporizing fuel to a fuel cell is provided. As the fuel travels in a flow field channel in the fuel distribution structure, it is substantially converted to a vapor by the heat of the fuel cell operation in such a manner that the resulting vapor pressure works to substantially uniformly distribute fuel evenly outwardly across substantially the entire active area of the anode aspect of one or more membrane electrode assemblies in the system, and whereby localized, uneven “hot spots” of fuel at the anode aspects are substantially prevented. A pair of enthalpy exchanger and heat spreader assemblies include a cathode current collector element that also has a heat spreader plate that collects and redirects heat in the fuel cell system, the assembly acting to manage the heat, temperature and condensation in the fuel cell system. |
| US08735009B2 |
Control unit for fuel-cell power generation apparatus, and control method, control program and computer-readable record medium with control program for the same
A control unit operates a fuel-cell power generation apparatus efficiently according to power consumption and supplied hot-water heat consumption which are different in each home. A generated-power command-pattern creation section creates a plurality of generated-power command patterns which are obtained from a combination of a start time and a stop time of the fuel-cell power generation apparatus, based on a power-consumption prediction value. A hot-water storage-tank heat-quantity calculation section calculates a stored hot-water heat quantity for a predetermined period in a hot-water storage tank, based on a supplied hot-water heat-consumption prediction. A fuel-cell system-energy calculation section calculates fuel-cell system energy which indicates the energy of a fuel required in hot-water supply equipment and electricity required in electric equipment when the fuel-cell power generation apparatus is operated in each generated-power command pattern. Additionally, an optimum command-pattern selection section operates the fuel-cell power generation apparatus in a generated-power command pattern which minimizes the fuel-cell system energy. |
| US08735007B2 |
Fuel cell system and operation method therefor
An alkaline fuel cell having an electrolyte, and anode and cathode electrodes disposed on two sides of the electrolyte is provided. A fuel cell system has this fuel cell, a discharge passageway that is connected to a discharge opening of the fuel cell and that discharges from the fuel cell an exhaust fuel containing unreacted fuel, and a circulation passageway that is connected to an introduction opening for introducing the fuel into the fuel cell and that circulates and supplies the exhaust fuel to the fuel cell. The fuel cell system further includes fuel/water separation means linked to the discharge passageway and the circulation passageway and disposed between the discharge and circulation passageways. The means separates and removes water from the exhaust fuel flowing in from the discharge passageway, and then causes a concentrated fuel from which water has been separated and removed to flow into the circulation passageway. |
| US08735006B2 |
Aqueous electrolyte battery and manufacturing method of aqueous electrolyte battery
An aqueous electrolyte battery is provided with a positive electrode, a negative electrolyte, an aqueous electrolyte, and a deposition portion that promotes deposition of discharge product and that is provided at a location that contacts the aqueous electrolyte and that is a location other than at a catalyst included in the positive electrode. |
| US08735003B2 |
Lithium-ion batteries having conformal solid electrolyte layers
Hybrid solid-liquid electrolyte lithium-ion battery devices are disclosed. Certain devices comprise anodes and cathodes conformally coated with an electron insulating and lithium ion conductive solid electrolyte layer. |
| US08735002B2 |
Lithium sulfur electrochemical cell including insoluble nitrogen-containing compound
An electrochemical cell including at least one nitrogen-containing compound is disclosed. The at least one nitrogen-containing compound may form part of or be included in: an anode structure, a cathode structure, an electrolyte and/or a separator of the electrochemical cell. Also disclosed is a battery including the electrochemical cell. |
| US08734999B2 |
Carbon nanotube forming substrate, carbon nanotube complex, energy device, method for manufacturing energy device, and apparatus including energy device
Provided are a substrate on which carbon nanotubes each having one end connected to the substrate can be formed at a high synthetic rate and from which the carbon nanotubes are less likely to be peeled off. The substrate is a substrate for forming the carbon nanotubes and includes a buffer layer 13 formed on at least one of surfaces of a substrate main body 14 and containing aluminum atoms and fluorine atoms. The carbon nanotube complex includes the substrate and a plurality of carbon nanotubes 11 each having one end connected to a surface of the buffer layer 13. |
| US08734997B2 |
Negative electrode for nonaqueous electrolyte secondary battery
A negative electrode 100 for a nonaqueous electrolytic secondary cell includes a current collector 1 and a plurality of active material bodies 2 formed on a surface of the current collector 1 at intervals; each active material body 2 contains a material for occluding or releasing lithium; and a plurality of projections 3 are formed on a part of a side surface of each active material body 2. |
| US08734995B2 |
Nonaqueous electrolyte battery, battery pack and vehicle
A nonaqueous electrolyte battery includes a negative electrode including a current collector and a negative electrode active material having a Li ion insertion potential not lower than 0.4V (vs. Li/Li+). The negative electrode has a porous structure. A pore diameter distribution of the negative electrode as determined by a mercury porosimetry, which includes a first peak having a mode diameter of 0.01 to 0.2 μm, and a second peak having a mode diameter of 0.003 to 0.02 μm. A volume of pores having a diameter of 0.01 to 0.2 μm as determined by the mercury porosimetry is 0.05 to 0.5 mL per gram of the negative electrode excluding the weight of the current collector. A volume of pores having a diameter of 0.003 to 0.02 μm as determined by the mercury porosimetry is 0.0001 to 0.02 mL per gram of the negative electrode excluding the weight of the current collector. |
| US08734994B2 |
Cathode active material, cathode including the same, and lithium battery including cathode
A cathode active material including a lithium metal oxide represented by Formula 1 below: Li[LixMeyM′z]O2+d Formula 1 wherein x+y+z=1, 0 |
| US08734990B2 |
Positive electrode of lithium secondary battery and method for producing the same
The present invention provides a positive electrode (30) for lithium secondary batteries, including: a barrier layer, having a conductive material and at least one type of water-insoluble polymer that is soluble in organic solvents but insoluble in water, as a binder; and a positive electrode active material layer, being a positive electrode active material layer (35) stacked on the barrier layer, and having a positive electrode active material and at least one type of aqueous polymer that is insoluble in organic solvents but soluble or dispersible in water, as a binder. A content of the water-insoluble polymer in the barrier layer is 55 to 85 mass % with respect to 100 mass % of a total amount of the conductive material plus the water-insoluble polymer. |
| US08734978B2 |
Battery pack
A battery module includes a first end plate and a second end plate, each of the end plates including at least one flange; a plurality of battery units arranged along a first direction between the end plates; a first guide plate on a first side of the plurality of battery units, extending in the first direction and coupled to the flanges of the first and second end plates; and a second guide plate on a second side of the plurality of battery units opposite the first side, extending in the first direction and coupled to the flanges of the first and second end plates. |
| US08734971B2 |
Fluid passage structure for fuel cell stack
A fluid passage structure for a fuel cell stack according to this invention comprises an internal manifold (16) formed on an inner side of a laminated body (1) of a plurality of fuel cells in a lamination direction, an external fluid passage (22) that supplies a fluid to the internal manifold (16), and a connection portion (16a) that connects the fluid passage to the internal manifold. Each fuel cell comprises an in-cell fluid passage (15) that is connected to the internal manifold (16) from an orthogonal direction. By forming the connection portion (16a) such that a swirl is generated in the internal manifold (16) using the energy of the fluid that flows into the internal manifold (16) from the fluid passage (22), a pressure deviation in a transverse section of the internal manifold (16) is reduced, and the fluid supply rate to each in-cell fluid passage (15) is made even. |
| US08734960B1 |
High density powdered material liner
A die set for forming explosive charge liners from powdered material comprises a die block defining a basin and a punch shaped to interact with the basin. The die block and the punch are configured to exclude powdered material from a center axis of the basin. An apparatus comprises a deep-penetrating explosive charge liner formed of powdered material held together by green strength having a hole in a narrow end of the liner. |
| US08734959B2 |
Barrier material and method for making the same
The present invention relates to a biopolymer based barrier coating composition wherein said biopolymer based barrier coating composition comprises a plasticizer, a nano-sized clay and a biopolymer comprising a native starch and/or a de-graded starch and/or a chemically modified starch. The present invention also relates to a method for preparing the biopolymer based barrier coating composition as well as to a method for coating a cellulose based substrate with the biopolymer based barrier coating composition. Finally, the present invention relates to a cellulose based substrate coated with said biopolymer based barrier coating composition. |
| US08734955B2 |
Transparent laminate and process for producing the same
A transparent laminate is produced by preparing a pair of transparent substrates, forming a sealing portion along the periphery on one of the transparent substrates for sealing a curable resin composition, supplying the curable resin composition in a region on the transparent substrate surrounded by the sealing portion, overlaying the other transparent substrate on the supplied curable resin composition in a reduced pressure atmosphere so that the curable resin composition is sealed as it is sandwiched between the pair of transparent substrates, and subsequently curing the curable resin composition in an atmosphere having a higher pressure than the pressure of the atmosphere in which the composition is sandwiched, to produce the transparent laminate. |
| US08734952B2 |
Optical retardation film and method of production thereof
The present invention relates generally to the field of organic chemistry and particularly to the optical retardation films for liquid crystal displays. The present invention provides an optical film comprising a substrate having front and rear surfaces, and at least one solid retardation layer on the front surface of the substrate. Said solid retardation layer comprises rigid rod-like macromolecules comprising n organic units of the first type having general structural formula I and k organic units of the second type having general structural formula II |
| US08734951B2 |
Polyurethanes, articles and coatings prepared therefrom and methods of making the same
The present invention provides polyurethanes including a reaction product of components including: (a) at least one polyisocyanate selected from the group consisting of polyisocyanate trimers and branched polyisocyanates, the polyisocyanate having at least three isocyanate functional groups; and (b) at least one aliphatic polyol having 4 to 18 carbon atoms and at least two hydroxyl groups, wherein the reaction product components are essentially free of polyester polyol and polyether polyol; compositions, coatings and articles made therefrom and methods of making the same. |
| US08734948B2 |
Superabsorbent polymer compositions having a triggering composition
The present invention relates to absorbent compositions which exhibit swelling, deswelling, and reswelling behavior. More specifically, absorbent compositions of this invention swell and absorb fluids after exposure to aqueous fluids, deswell and release fluids from the swollen absorbent compositions, and may also reswell and absorb fluids. The swelling-deswelling-reswelling behavior allows enhanced liquid distribution in absorbent composites. |
| US08734946B2 |
Product with tailored wettability
A product which at least partly comprises an agglomerate formed from a powder having a pre-determined wettability. |
| US08734945B2 |
D1364 BT secondary coatings on optical fiber
The invention relates to a Radiation Curable Secondary Coating composition for use on an Optical Fiber. The Radiation Curable Secondary Coating composition is a urethane-free Alpha Oligomer prepared by reaction of the following: (a) an acrylate compound selected from an alcohol-containing acrylate or alcohol-containing methacrylate compound, (b) an anhydride compound, (c) an epoxy-containing compound, (d) optionally an extender compound, and (e) optionally a catalyst. The invention also relates to a coated wire and to a coated optical fiber. |
| US08734941B2 |
Use of chemical admixtures as promotors, recovery agents
The present invention is directed to an energy absorption system for absorbing mechanical impact energy using one or more chemicals for promoting absorption of a liquid, and optionally including one or more promoter, recovery agent, and/or viscosity adjusting agent, which allows the system to release the absorbed energy. |
| US08734939B2 |
Thermally reversible hot melt adhesive composition containing multifunctional diene and dienophile compounds
The invention relates to a thermally reversible hot melt adhesive that is isocyanate-free, moisture independent, crosslinkable and thermally reversible. The thermally reversible hot melt adhesive may be repeatedly heated and cooled without negatively affecting the performance of the adhesive. The thermally reversible composition may also be used as a primer layer. The thermally reversible hot melt adhesive and primer are particularly well suited for end use applications such as packaging, graphic arts, construction, footwear, textiles, general assembly, automotive and consumer goods. |
| US08734938B2 |
Method of cutting out chips for a plurality of sensor elements from laminated body, method of manufacturing sensor element, and sensor element
A sensor element is formed by cutting a laminated body and heating with the cutting taking place in a state where a difference in resistance on sides of a cutting component is as small as possible. That is, a uniform cutting is where resistance added to both sides of the cutting component is substantially the same. When uniform cutting cannot be performed, a nonuniform cutting in a state where resistance added to both sides of the cutting component is different is performed. Consequently, a surface perpendicular to a longitudinal direction of the sensor element is trapezoidal. |
| US08734935B2 |
Scratch-resistant silicone coating for cooktops made of glass or glass ceramic
A functional element, in particular a cooktop or control panel, having a flat substrate composed of or of glass or glass ceramic, in which a coating that contains a crosslinked polysiloxane is applied to the substrate. In order to improve the scratch resistance of such a coating, according to this invention, a covering layer that contains an uncrosslinked polysiloxane is applied to the coating. |
| US08734932B2 |
Drainage mat
A drainage mat for use in building structures, particularly in exterior walls and roofing, to improve drainage and ventilation within such structures. The drainage mat includes a web of extruded polymer monofilaments that are heat welded at junctions to form a matrix of tangled monofilaments. The web includes on its front face an alternating array of ridges and planar regions, each ridge having a substantially trapezoidal shape with a top surface and a base, the width of the top surface being less than the width of the base. |
| US08734925B2 |
High pressure molding of composite parts
Composite pre-forms are molded at high pressure to form composite parts that can be used in place of metal-based high performance parts, such as the outlet guide vanes found in turbofan jet engines. The composite pre-forms include two different fiber orientations that are co-molded in a resin matrix at high pressures to provide composite outlet guide vanes and other high performance parts. Chambers within the composite part are optionally formed during molding of the pre-form at high pressures. |
| US08734924B2 |
Laminate structure comprising a lipophilic gel for containing electrolyte leaks
Implementations and techniques for containing electrolyte leaks are generally disclosed. |
| US08734922B2 |
Multilayer film for packaging fluid products
Co-extruded multilayer packaging films suitable for packaging fluid products, showing a very good balance of mechanical, chemical and, optionally, barrier properties, good sealability, heat resistance and unexpectedly improved optical properties, a process for their manufacturing, pouches and packages obtained from them, are disclosed. These films comprise a core layer (D) comprising a polyamide; two tie layers (C), directly adhered to the opposite surfaces of the core layer; at least one intermediate layer (B), directly adhered to the opposite surface of a tie layer (C), comprising high density polyethylene; and two outer layers (A) comprising an ethylene/alpha olefin copolymer. |
| US08734920B2 |
Coated article with low-E coating having titanium oxide layer and/or NiCr based layer(s) to improve color values and/or transmission, and method of making same
Certain example embodiments relate to a coated article including a low-E coating. In certain example embodiments, a titanium oxide inclusive bottom layer stack and/or a NiCr-based layer(s) are designed to improve b* coloration values and/or transmission of the coated article. These layer stack portions also advantageously permit a double-silver coated article to achieve (i) an LSG value (Tvis/SHGC) of at least 2.0, (ii) an SHGC value of no greater than 35%, and (iii) a U-value (BTU h−1 ft−2° F.−1) (e.g., x=12 mm) of no greater than 0.30. In certain example embodiments, the titanium oxide based layer may be an interlayer provided in a bottom portion of the layer stack between first and second layers comprising silicon nitride. Coated articles according to certain example embodiments may be used in the context of insulating glass (IG) window units, other types of windows, or in any other suitable application. |
| US08734917B2 |
Liquid crystal display device
A liquid crystal display device includes: a pair of substrates, at least one of which is transparent; a liquid crystal layer placed between the pair of substrates; an electrode group, formed on at least one of the pair of substrates, for applying an electric field to the liquid crystal layer; and an alignment control film placed on at least one of the pair of substrates, in which the alignment control film is formed of polyimide and a precursor of the polyimide, each of the polyimide and the precursor of the polyimide contains, as a material, a specific cyclobutanetetracarboxylic acid dianhydride derivative and aromatic diamine, and the alignment control film is provided with alignment capability by photo-alignment treatment. |
| US08734916B2 |
Optical device
An optical device and a stereoscopic image display device are provided. The optical device according to one embodiment may be a light-dividing device, for example, a device that can divide incident light into at least two kinds of light having different polarized states. For example, the optical device can be used to realize a stereoscopic image. |
| US08734915B2 |
Film-formation method and manufacturing method of light-emitting device
A film-formation method whereby a minute pattern thin film can be formed on a deposition substrate, without provision of a mask between a material and the deposition substrate. Moreover, a light-emitting element is formed by such a film-formation method, and a high-definition light-emitting device can be manufactured. Through a film-formation substrate in which a reflective layer, a light-absorbing layer and a material layer are formed, the light-absorbing layer is irradiated with light, so that a material contained in the material layer is deposited on a deposition substrate which is disposed to face the film-formation substrate. Since the reflective layer is selectively formed, a film to be deposited on the deposition substrate can be selectively formed with a minute pattern reflecting the pattern of the reflective layer. A wet process can be employed for formation of the material layer. |
| US08734914B2 |
Film formation method and method for manufacturing light-emitting device
A binder material layer including an evaporation material is formed over a main surface of an evaporation source substrate, a substrate on which a film is formed is placed so that the binder material layer and a main surface thereof face each other, and heat treatment is performed on a rear surface of the evaporation source substrate so that the evaporation material in the binder material layer is heated to be subjected to sublimation or the like, whereby a layer of the evaporation material is formed on the substrate on which a film is formed. When a low molecular material is used for the evaporation material and a high molecular material is used for the binder material, the viscosity can be easily adjusted, and thus, film formation is possible with higher throughput than conventional film formation. |
| US08734913B2 |
Formation method of coating
A formation method of a coating that coats a coated body with the coating includes: generating cylindrical plasma in a vacuum deposition chamber as well as supplying material gas into the vacuum deposition chamber; applying pulse voltage to the coated body; and attaching a shield member that shields an uncoated member to an uncoated part where the coating of the coated body is not formed with separation spacing over a coated part where the coating is to be formed for preventing decrease of hardness of the coating in the coated part. |
| US08734912B2 |
Method for patterning substrate and method for fabricating capacitive touch panel
A method for patterning a substrate is presented, which includes the following steps. A conductive material is jet-printed onto a part of at least one side of the substrate. A surface of the at least one side of the substrate is imprinted with a laser to pattern a first conductive pattern. By using the method, the process can be simplified and substrates of a touch panel can be integrated, so as to achieve an objective of decreasing the overall thickness of an electronic device. |
| US08734908B2 |
Resin-coated metal pigment, method for producing the same, and water base paint using the same
The present invention provides a resin-coated metal pigment capable of achieving both of water resistance of a water base paint and chemical resistance of a film at a high level, and a water base paint using the resin-coated metal pigment. The present invention provides a method for producing a resin-coated metal pigment including an adsorption step of bringing a solution or a dispersion liquid of a phosphate ester component (A) into contact with a metal pigment to prepare a phosphate ester adsorbing metal pigment, a slurry preparation step of preparing a slurry for polymerization obtained by dissolving a polymerization component (B) therein, and a coating step of polymerizing the polymerization component (B) to form a resin coating layer on the surface of the phosphate ester adsorbing metal pigment; a resin-coated metal pigment obtained by the method; and a water base paint using the resin-coated metal pigment. |
| US08734907B2 |
Coating of shield surfaces in deposition systems
A deposition chamber shield having a stainless steel coating of from about 100 microns to about 250 microns thick wherein the coated shield has a surface roughness of between about 300 microinches and about 800 microinches and a surface particle density of less than about 0.1 particles/mm2 of particles between about 1 micron and about 5 microns in size and no particles below about 1 micron in size, and process for production thereof is disclosed. |
| US08734905B2 |
Thermally protective materials
A mixture comprising an expandable graphite and a polymer resin is described wherein the polymer resin-expandable graphite mixture has a volume increase and structural integrity after exposure to heat. Methods are described for increasing the thermal protective performance (TPP) of textiles and laminates while optionally maintaining comfort, flexibility, and liquid protective properties. |
| US08734903B2 |
Process for forming a silica coating on a glass substrate
A chemical vapor deposition process for the deposition of a silica layer on a glass substrate is provided. The process includes providing a glass substrate. The process also includes forming a gaseous precursor mixture comprising a silane compound, oxygen, water vapor, and a radical scavenger and directing the precursor mixture toward and along the glass substrate. The mixture reacts over the glass substrate to form a silica coating thereon. |
| US08734899B2 |
Modified particles and dispersions comprising these
The present invention relates to particles which have been modified by a modifier and a dispersion medium comprising the modified particles.The surface-modified metal, metal halide, metal chalcogenide, metal nitride, metal phosphide, metal boride or metal phosphate particles or mixtures thereof have an average particle diameter of from 1 to 500 nm and their surface has been modified by one or more modifiers of the formula (I) (II) and (III) |
| US08734897B2 |
Method for producing a multilayer concrete-based coating on a ceramic or earthenware surface
A method for producing a decorative coating on a surface made of a mineral compound that is ceramic or earthenware, the method including: depositing an adhesive primer layer on said surface made of a mineral compound; depositing a concrete layer; hardening said concrete layer; and depositing a decorative layer. Advantageously, the concrete may be a self-leveling concrete. |
| US08734896B2 |
Methods of manufacturing high-strength large-area sputtering targets
A joined sputtering target comprising a sputtering material is formed by disposing two discrete sputtering-target tiles comprising the sputtering material proximate each other, thereby forming an interface between the tiles, the interface comprising at least one of an interlocking joint therein or a recess in a top surface thereof, and spray-depositing a spray material over at least a portion of the interface, thereby joining the tiles to form the joined sputtering target. |
| US08734895B2 |
Grease, oil and wax resistant paper composition
In order to provide grease, oil and wax resistance to a paper substrate, a coating containing a binder, a filler material and calcium carbonate is used. The coating of the invention is essentially free from fluorocarbons, which are considered harmful to human and animal populations, and surfactants and other chemicals which may alter the color of the coated paper. The coated paper has a GE brightness level between approximately 50 and approximately 90, while providing superior grease, oil and wax resistance. |
| US08734894B2 |
Self-aligned bevels for write poles
A method of depositing material onto a base portion of a wafer is disclosed. The method includes forming a bevel into a portion of a surface of the base portion of the wafer and depositing a first layer of conductive material onto the beveled portion of the base portion so that part of the first layer includes a wedge shape above the surface of the base portion. A second layer of conductive material is deposited onto the base portion including the portion of the base portion onto which the first layer of material is deposited. |
| US08734887B2 |
Aqueous dough conditioning composition
An aqueous dough conditioning composition comprises water, one or more enzymes, salt and sugar characterized in that the composition in substantially free of antioxidant. Preferably, the composition comprises less than 0.05% by wt of antioxidant. The composition may further comprise an oxidant and/or a hydrocolloid. The invention also provides dough comprising the aqueous conditioning composition, and baked products made therefrom. There is also provided the use of salt and sugar to stabilize an aqueous dough conditioning composition comprising one or more enzymes, the composition being substantially free of antioxidant. |
| US08734885B2 |
Cold infusion process for fortifying coffee beans
This invention relates to a cold infusion process for fortifying coffee beans with one or more vitamin, non-vitamin, mineral, non-mineral, botanical, hormone, herb, neutraceutical, lipid, carbohydrate, amino acid, acid, salt, prebiotic, or probiotic functional additives. This invention also discloses an infused coffee bean produced by the process of infusing the coffee bean at a temperature of less than about 120° F. with a solution comprising water, a bridge initiator for acid salt bias, fortifying agent(s), and an acid in a quantity sufficient to reach a pH of about 3.65. Further, this invention provides a method for the infusion of a coffee bean with at least one fortifying agent at approximately room temperature. |
| US08734878B2 |
Method to separate lipids from cheese whey
Shown is a method of selectively separating milk fat globule membrane fragments and milk fat globules from whey. The method includes the steps of adding to whey an amount of a whey-soluble zinc salt and adjusting the pH of the whey to be less than 6.0. The amount of zinc salt added to the whey is sufficient to cause milk fat globule membrane fragments and milk fat globules contained in the whey to precipitate selectively from the whey. |
| US08734876B2 |
Confectionary product and method of manufacture and use
A confectionary product has a hollow, pliable tube containing a flowable confectionary material and an enlarged head secured to one end of the tube, the opposite end of the tube being sealed. The head has one or more dispensing openings on its outer surface. In one case, the head is solid and a passageway extends through the head from an inlet end communicating with the tube at one end and at least one dispensing opening at the other end. In another case, the head is hollow and has a plurality of openings. The wall of the tube can be squeezed to force the flowable confection through the head and out through the opening or openings for consumption. In one embodiment, the head is of edible material such as hard candy and is consumed after substantially all of the confectionary material is squeezed out of the tube and consumed. |
| US08734875B1 |
Stuffed dough pocket with grasping extension
A food product includes a pocket formed from dough, a portion of a food stuffing material captured within the pocket, and a protrusion coupled to the pocket. The protrusion is capable of being grasped and, when so grasped, the pocket is capable of being supported by the protrusion. A method of manufacturing such a food product is also disclosed. The food product relates to pocket-foods such as pierogies, ravioli, and similar foods. |
| US08734871B2 |
Glycolipid fraction from cyanobacteria for treatment of diseases of the oral cavity
The present invention relates to the preparation and use of a glycolipid fraction from Oscillatoria Planktothrix sp., for the treatment and/or prevention of bacterial gum diseases primarily caused by: Actinobacillum actinomycetemconcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola and even more preferably by Porphyromonas gingivalis. Said gum diseases, in particular gingivitis and periodontitis (pyorrhea), are primarily caused by a pro-inflammatory response to components of P. gingivalis, leading to destruction of periodontal tissue, and are often accompanied by osteoclastogenesis (increased number of osteoclasts responsible for destruction of bone tissue), and by chronic infection. |
| US08734870B2 |
Dendrimers and dendrimer applications
An activatable functionalised Nth generation dendrimer having: a core comprising a first monomer having at least two carboxylic acid functional groups; and N successive generations, where N=0 to 10, wherein each generation comprises: a second monomer having at least two alcohol functional groups, wherein at least one alcohol group is bonded to a carboxylic acid group of the first monomer of the prior generation, and an additional first monomer attached to a second alcohol function group of said second monomer of that generation; and the final generation having attached thereto at said second alcohol functional group of said second monomer, a moiety having a dicarboxylic acid functional group, activatable by treatment with a carboxylic acid activating reagent such that reactivity of the carboxylic acid functional group is increased. The dendrimer, when activated, may be used in applications such as polymer crosslinking and/or nanoshell production. |
| US08734869B2 |
Synergistic pest-control compositions
Pest control compositions, blends, and formulations are disclosed. The blends contain, in a synergistic combinations, at least two ingredients such as Lilac Flower Oil, D-Limonene, Thyme Oil, Lime Oil, Black Seed Oil, Wintergreen Oil, Linalool, Tetrahydrolinalool, Vanillin, Isopropyl myristate, Piperonal (aldehyde), Geraniol, Geraniol 60, Triethyl Citrate, and Methyl Salicylate. |
| US08734866B2 |
Composition comprising the extracts of lindera obtusiloba for prevention and treatment of cardiovascular diseases
The present invention relates to a composition for treatment and prevention of cardiovascular diseases, containing an extract of Lindera obtusiloba. More particularly, the extract of Lindera obtusiloba strongly inhibits NAD(P)H oxidases, which are the main cause of vascular diseases, and at the same time, regulates contraction and relaxation of vascular smooth muscles to manifest a potent vasorelaxant effect, thereby improving the blood pressure regulation and vascular endothelial dysfunction. Therefore, a composition containing this as an active ingredient can be usefully utilized as a pharmaceutical product or health functional food product for the prevention and treatment of cardiovascular diseases. |
| US08734862B2 |
Granular bioplastic biocontrol composition
Previous research demonstrated that aflatoxin contamination in corn is reduced by field application of wheat grains pre-inoculated with the non-aflatoxigenic Aspergillus flavus strain NRRL 30797. We evaluated the reliability and efficiency of replacing wheat grains with the novel bioplastic formulation Mater-Bi® to serve as a carrier matrix to formulate strain NRRL 30797. Mater-Bi® granules were inoculated with a conidial suspension of NRRL 30797 to achieve a final cell density of ˜log 7 conidia/granule. Incubation of 20-g soil samples receiving a single Mater-Bi® granule for 60-days resulted in log 4.2 to 5.3 propagules of A. flavus/g soil for microbiologically active and sterilized soil, respectively. The bioplastic formulation was highly stable; Mater-Bi® is a suitable substitute for biocontrol applications of A. flavus NRRL 30797. |
| US08734852B2 |
Parenteral controlled release formulations of NSAID's
A controlled release parenteral formulation for treatment of pain and inflammation is provided. The formulation includes an effective amount of: one or more active drug moiety. The drug moiety is selected from a group comprising aceclofenac or diclofenac or a combination thereof; One or more solvent moiety selected from a group comprising one or more of ethyl acetate, triacetin, di methyl iso sorbide, DMA, DMSO, PEG, PVP, PVA, Span 80, DCM, Benzyl alcohol, acetone or a combination thereof. The formulation, upon administration, has a release profile including an immediate burst release and the burst release is followed by a slow release of at least 18 to 24 hrs. The immediate burst release and the slow release of the drug moiety remains within the therapeutic window of the drug moiety. |
| US08734851B2 |
Localized delivery of nucleic acid by polyelectrolyte assemblies
The present invention provides implantable medical devices coated with polyelectrolyte assemblies that are fabricated by layer-by-layer deposition of nucleic acid and polycation. Such devices facilitate the local delivery of a nucleic acid contained in the polyelectrolyte assembly into a cell or tissue at an implantation site. Also provided are methods of fabricating and using implantable medical devices according to the invention. |
| US08734845B2 |
Diketopiperazine microparticles with defined specific surface areas
Disclosed herein are diketopiperazine microparticles having a specific surface area of less than about 67 m2/g. The diketopiperazine microparticle can be fumaryl diketopiperazine and can comprise a drug such as insulin. |
| US08734844B2 |
Solid phase gold nanoparticle synthesis
A method of synthesizing ligand-conjugated gold nanoparticles (AuNPs) is disclosed. The method comprises: a) providing an amine-modified silica particle; b) providing a solution comprising Au+3 ions; c) suspending the amine-modified silica particle in the solution comprising Au+3 ions; d) allowing the Au3+ ions to be adsorbed and/or immobilized onto the surface of the amine-modified silica particle; e) exposing the Au3+ ions immobilized onto the surface of the amine-modified silica particle to radiation to obtain bare gold nanoparticles (AuNPs) adsorbed and/or immobilized onto the surface of the amine-modified silica particle, wherein the bare AuNPs are without organic surface modifications; and f) reacting a ligand with the bare AuNPs adsorbed and/or immobilized onto the surface of the amine-modified SiNP and thereby obtain ligand-conjugated gold nanoparticles (AuNPs). |
| US08734838B2 |
Adhesive containing polyisoprene, sis copolymer, and solid/liquid polyisobutylene for external use on skin
A pressure-sensitive adhesive composition which comprises three ingredients, i.e., polyisoprene, a styrene/isoprene/styrene copolymer, and solid polyisobutylene, in a proportion of (10-60)/(10-50)/(20-60) by weight and further contains a non-solid isobutylene polymer and a tackifier, characterized in that the amount of the non-solid isobutylene polymer is 1 to 30 pts. wt., excluding 30 pts. wt., per 100 pts. wt. of the sum of the three ingredients, i.e., the polyisoprene, styrene/isoprene/styrene copolymer, and solid polyisobutylene. When used in an adhesive patch for external use on the skin, the composition has satisfactory tackiness regardless of whether the temperature of the surrounding air is high or low, has excellent long-term storage stability, retains the necessary cohesive force, and does not unnecessarily irritate the skin. |
| US08734831B2 |
Method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid coating layer containing a bioactive factor
A method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid coating layer containing a bioactive factor includes (a) forming a porous ceramic scaffold; (b) mixing a silica xerogel and a physiologically active organic substance in a volumetric ratio ranging from 30:70 to 90:10 and treating by a sol gel method to prepare an organic/inorganic hybrid composite solution; (c) adding a bioactive factor to the organic/inorganic hybrid composite solution and agitating until gelation occurs; and (d) coating the porous ceramic scaffold with the organic/inorganic composite containing the bioactive factor added thereto. In accordance with the method, the porous ceramic scaffold may be uniformly coated with the organic/inorganic hybrid composite while maintaining an open pore structure, and stably discharge the bioactive factor over a long period of time. |
| US08734829B2 |
Medical devices having polymeric nanoporous coatings for controlled therapeutic agent delivery and a nonpolymeric macroporous protective layer
An implantable or insertable medical device is provided which contains the following: (a) a substrate, (b) a therapeutic agent-containable region disposed over the substrate, (c) a nanoporous polymeric layer disposed over the therapeutic agent-containable region and (d) a macroporous non-polymeric layer disposed over the nanoporous polymeric layer. The nanoporous polymeric layer largely regulates transport of species between the therapeutic agent-containable region and the exterior of the device. The macroporous non-polymeric layer has a larger pore size than the nanoporous polymeric layer and largely serves to isolate the polymeric material from surrounding tissue during in-situ delivery of the therapeutic agents. |
| US08734822B2 |
Composite shaped bodies and methods for their production and use
Shaped, composite bodies are provided. One portion of the shaped bodies comprises an RPR-derived porous inorganic material, preferably a calcium phosphate. Another portion of the composite bodies is a different solid material, preferably metal, glass, ceramic or polymeric. The shaped bodies are especially suitable for orthopaedic and other surgical use. |
| US08734820B2 |
Soil amendment compositions and methods for using the same
Soil amendment compositions and methods for using the same are provided. The subject compositions are aqueous compositions consisting essentially of a carbon-skeleton energy component, a predisposing agent and a vitamin-cofactor component. The subject compositions find use in a variety of soil amendment applications, including: the control of soil born pests and pathogens; the improvement in soil fertility and/or characteristics, e.g. mineral release, water filtration; the neutralization and/or degradation of toxins, etc. |
| US08734819B2 |
Animal-repelling synthetic resin composition
An article, such as a container or bag for garbage, or electrical wiring insulation, which repels animals such as cats, dogs, rodents, and crows. The article is made from a synthetic resin composition including a thermoplastic polymer, and from 10 to 15,000 ppm by weight of an odorant compound such as a salicylic acid ester, menthol, corn mint oil, eucalyptus oil, and camphor, and combinations thereof. The resin composition may comprise more than one thermoplastic polymer, polyethylene and ethylene/vinyl acetate copolymer being preferred first and second thermoplastic polymers, respectively. In a method for forming the synthetic resin composition, the compound is added to the second polymer in a ratio of about 1:2 parts by weight to form a master blend that then is added to an amount of the first polymer at a master blend percentage of about 1.5%. |
| US08734818B2 |
Methods for treating cognitive/attention deficit disorders using tetrahydroindolone analogues and derivatives
The present specification discloses tetrahydroindolone derivatives or analogues and methods for treating cognitive/attention deficit disorders using such tetrahydroindolone derivatives and analogues. |
| US08734816B2 |
Porous nanoparticle supported lipid bilayer nanostructures
Various exemplary embodiments provide protocell nanostructures and methods for constructing and using the protocell nanostructures. In one embodiment, the protocell nanostructures can include a core-shell structure including a porous particle core surrounded by a shell of lipid bilayer(s). The protocell can be internalized in a bioactive cell. Various cargo components, for example, drugs, can be loaded in and released from the porous particle core of the protocell(s) and then delivered within the bioactive cell. |
| US08734812B1 |
Neisserial antigenic peptides
This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria Neisseria meningitidis B. Also provided are nucleic acids encoding for such proteins, polypeptides, and/or fragments, as well as nucleic acids complementary thereto (e.g., antisense nucleic acids). Additionally, this invention provides antibodies which bind to the proteins, polypeptides, and/or fragments. This invention further provides expression vectors useful for making the proteins, polypeptides, and/or fragments, as well as host cells transformed with such vectors. This invention also provides compositions of the proteins, polypeptides, fragments, and/or nucleic acids, for use as vaccines, diagnostic reagents, immunogenic compositions, and the like. Methods of making the compositions and methods of treatment with the compositions are also provided. This invention also provides methods of detecting the proteins, polypeptides, fragments, and/or nucleic acids. |
| US08734810B2 |
Botulinum toxin treatments of neurological and neuropsychiatric disorders
Methods for preventing or treating neuropsychiatric disorder and/or a neurological disorder including a neurological disorder mediated by the thalamus. Neuropsychiatric disorders and/or a neurological disorders, including a thalamically mediated disorder can be treated by peripheral administration of a botulinum toxin to or to the vicinity of a trigeminal sensory nerve, thereby preventing or treating a neurological disorder and/or a neuropsychiatric disorder. |
| US08734807B1 |
Preventing and curing Schistosomiasis mansoni by inhibiting Trk receptors on female Schistosoma
Schistosomiasis mansoni is caused by flukes called Schistosoma(es) that enters the human body through the skin in Schistosoma infested waters. The Schistosomes travel from the skin into human blood vessels where they mate, produce antigen containing eggs that travel from the blood vessels into the small intestines, where they are released in the human feces. Male and female Schistosome mates in human blood vessels, male Schistosomes secrete a protein called TGR β protein to the Trk receptor sites on the females Schistosomes membranes. The process stimulates the formation of chemical SmInAct in female Schistosomes, a chemical necessary for the female Schistosomes to produce eggs. This novel technique describes new methods to inhibit Trk receptor sites on female Schistosome membranes using Trk inhibitor agent to prevent TGR β proteins from binding to the Trk receptor sites. Thus, preventing SmInAct from being created in female Schistosomes, preventing production of eggs and Schistosomiasis. |
| US08734804B2 |
Treatment of myelosuppression
Methods are presented for attenuating myelosuppressive side effects of treatment regimens, promoting thrombopoiesis and neutrophil production, and increasing efficacy of treatment regimens, by administering PF4-interacting heparinoids. |