Document Document Title
US08717013B2 Device for detecting damage of a test specimen made of ferromagnetic material
The device comprises a magnetization unit, which generates a constant magnetic field, to which the test specimen (12) is exposed so as to magnetize it. The magnetization unit and test specimen (12) carry out a relative motion to each other, thereby inducing eddy currents in the test specimen (12). The magnetization unit has at least one yoke (10) projecting in the direction of the relative motion. In addition to a probe (14), which is offset toward the back with respect to the magnetization unit in the direction of the relative motion and which is suited to detect damage based on the influence of the damage on the induced eddy current, the device comprises at least one further probe (16) between the yoke limbs of the magnetization unit.
US08717011B2 Actuator
In the case of an actuator having a rotation angle sensor with a magnet, no satisfying solution has yet been found for the attachment of the magnet. The invention relates to an actuator having a rotation angle sensor, the magnet of the rotation angle sensor being provided with a plastic cover. The plastic cover and magnet may be easily connected to a first sensor part of the rotation angle sensor of the actuator. The actuator with the rotation angle sensor can particularly be used in motor vehicles.
US08717009B2 Magnetometer calibration
A real-time calibration system and method for a mobile device having an onboard magnetometer uses an estimator to estimate magnetometer calibration parameters and a magnetic field external to the mobile device (e.g., the earth magnetic field). The calibration parameters can be used to calibrate uncalibrated magnetometer readings output from the onboard magnetometer. The external magnetic field can be modeled as a weighted combination of a past estimate of the external magnetic field and the asymptotic mean of that magnetic field, perturbed by a random noise (e.g., Gaussian random noise). The weight can be adjusted based on a measure of the statistical uncertainty of the estimated calibration parameters and the estimated external magnetic field. The asymptotic mean of the external magnetic field can be modeled as a time average of the estimated external magnetic field. are within the scope of the following claims.
US08717008B2 Fan speed testing system
A fan speed testing system includes a voltage regulating module, a rotational frequency collecting module, and a rotational frequency converting module. The voltage regulating module receives an AC voltage signal and converts the AC voltage signal to a variable first DC voltage signal to adjust a rotational speed of a fan. The rotational frequency collecting module detects the rotational speed of the fan and outputs rotational frequency signals. The rotational frequency converting module receives the rotational frequency signals and determines the rotational speed of the fan according to numbers and period of time level voltage switching in the rotational frequency signals.
US08717006B2 Method of performing synthetic instrument based noise analysis using proportional bandwidth spectrum analysis techniques
A system and method for filtering an input signal with at least a first and a second octave portions is presented. A proportional bandwidth filter system includes a bandwidth reducing filter, a down-sampler, and first and second octave filters. The bandwidth reducing filter reduces the bandwidth of the input signal and the down-sampler rolls the second octave portion represented in the reduced bandwidth signal to a top octave portion of a down-sampled signal. The first and second octave filters are comprised of a plurality of proportional bandwidth filters. The first octave filter partitions and converts the first octave portion of the input signal into output signals representing the frequency spectra of the first octave of the input signal. Similarly, the second octave filter generates outputs representing the spectra of the second octave portion of the input signal represented as the top octave portion of a down-sampled signal.
US08717004B2 Circuit comprising transistors that have different threshold voltage values
A circuit comprises a first amplifier and a second amplifier. The first amplifier is configured to amplify a first voltage difference between a first voltage and a second voltage, and to generate a third voltage. The second amplifier is configured to amplify a second voltage difference between the third voltage and an input voltage, and to generate an output voltage. The first voltage is a voltage at a first terminal of a first transistor. The second voltage is a voltage at a second terminal of a second transistor. A first gate of the first transistor is adapted to receive the third voltage. A second gate of the second transistor is adapted to receive the input voltage. Threshold voltage values of the first transistor and the second transistor differ.
US08717002B2 Constant on-time converter and control method thereof
A constant ON-time converter is disclosed. The constant ON-time converter comprises a feedback circuit, a slope compensation circuit and a buffer circuit. The feedback signal comprises an output configured to provide a feedback signal indicating an output voltage of the constant ON-time converter. The slope compensation circuit comprises an output configured to provide a slope compensation signal. The buffer circuit is coupled between the output of the feedback circuit and the output of the slope compensation circuit to avoid the feedback signal and the output voltage of the constant ON-time converter is influenced by the slope compensation signal.
US08716999B2 Dynamic frequency and pulse-width modulation of dual-mode switching power controllers in photovoltaic arrays
A converter unit configured to couple to a photovoltaic panel may include a controller that monitors: an output voltage and output current obtained from the photovoltaic panel by a switching power core within the converter unit, and an output voltage and output current produced by the switching power core. The controller may calculate a desired duty-cycle value based on the monitored values, and implement a mapping algorithm that translates the duty-cycle value to a pulse-width value and a modulus value. The pulse-width value and the modulus value may be used to simultaneously respectively modulate the pulse-width and pulse-period of a pulse-width modulated (PWM) signal, while maintaining an appropriate linear final duty-cycle ratio between the pulse-width and the pulse-period of the PWM signal. The PWM signal may be provided to the switching power core to control the switching of the switching power core.
US08716998B2 DC-DC converter and digital pulse width modulator
A DC-DC converter has a switching element, a lowpass filter, an oscillator, an AD converter, an error signal generator, a counter, a comparator, a selector configured to select one of the plurality of clock signals in accordance with a value of a lower side bit of the error signal in sync with a timing when the comparator detects coincidence, and a switching controller configured to control ON/OFF of the switching element in accordance with the clock signal selected by the selector. The selector selects one among the plurality of clock signals and a new clock signal generated by combining two or more clock signals comprising neighboring phases among the plurality of clock signals.
US08716996B2 Switching control circuit and AC/DC converter using the same
A switching control circuit for an AC/DC converter stops the switching of a switching device in a low-phase angle range of an AC power supply to prevent an improper recovery operation after a brownout is detected.
US08716992B2 Current limiting circuit and power supply circuit
A current limiting circuit for limiting an output current in response to a control current includes a detection circuit to detect a detection voltage responsive to an output voltage, and a control current generating circuit to generate a control current responsive to the detection voltage, wherein the control current generating circuit includes a first transistor through which the control current flows, a second transistor that becomes conductive upon a voltage responsive to an amount of the control current being greater than a predetermined voltage above the detection voltage, and a resistor connecting between a base and an emitter of the second transistor to raise a potential at the base of the second transistor above a predetermined level, wherein the amount of the control current flowing through the first transistor decreases as an amount of a current flowing through the second transistor increases.
US08716986B2 Power conversion circuit
A power conversion circuit which receives a high potential, a low potential, and a neutral potential intermediate between the high and low potentials includes an AC switch connected so as to receive the neutral potential and a switching device receiving the high potential. The AC switch includes a diode and an inductance is connected to the diode and the switching device.
US08716983B2 Vehicle-use electric rotating machine
A vehicle generator includes armature windings, rectifier module groups, an upper MOS on-timing determining section, a lower MOS on-timing determining section, a rotational speed calculating section, a target electrical angle setting section for setting a value of a target electrical angle, an upper MOS off-timing determining section, a lower MOS off-timing determining section, and drivers for driving high-side and low-side MOS transistors constituting upper and lower arms. The target electrical angle represents a margin period between when the low-side MOS transistor was turned off a half cycle ago and the moment when the lower arm on-period has ended. The upper MOS off-timing determining section and the lower MOS off-timing determining section set off timings of the MOS transistors such that the margin period is equivalent to the set value of the target electrical angle.
US08716981B2 System and method for cooling and cycling a battery pack
A system and a method for cooling and cycling a battery pack is provided. The system includes an air supplying device that outputs pressurized air. The system further includes a vortex tube that receives the pressurized air and outputs cooled air at a first temperature level utilizing the pressurized air. The system further includes at least one heat exchanger disposed in the battery pack that receives the cooled air from the vortex tube and cools the battery pack. The system further includes a battery cycling device configured to charge and discharge the battery pack when the battery pack is being cooled.
US08716979B2 Ambulatory medical device with electrical isolation from connected peripheral device
Methods and apparatus are provided for electrically isolating an ambulatory medical device for infusing treatment materials into a patient when the medical device is connected to a peripheral device via an active communication cable. In one embodiment, the ambulatory medical device includes first circuitry controlling infusion of a medicament to the patient by a fluid conduit connectable to the patient and second circuitry controlling communications when an active communication cable is connected to the medical device. The first and second circuitry are electrically isolated using a pair of first and second isolation transceivers, where the first pair of isolation transceivers communicate a control signal and the second pair of isolation transceivers are giant magneto-resistive (GMR) transceivers that communicate at least one data signal.
US08716978B2 Charging method and apparatus for electric vehicle
Disclosed are a charging apparatus and a charging method for a battery of an electric vehicle. The charging apparatus for a battery of an electric vehicle includes: a communication module that communicates power information and information on a battery of the electric vehicle; a charging mode setting module that receives a user's order; a charging switch that connects the battery of the electric vehicle with the charging power in accordance with an input control signal; and a charging control module that sets the charging amount of the battery by using the power information and the information on the battery, sets charging information including charging power and at least one time period for charging the battery of the electric vehicle within a predetermined time range, and input the control signal to the charging switch on the basis of the charging information.
US08716976B2 Contactless electricity-supplying device
A contactless electricity-supplying device (20) includes a secondary winding (201) to which electric power is supplied from a primary winding (101), by an AC power supply (6). The impedance characteristic (Z) of Z1 in regard to the frequency has a local maximum (ZMAX) near the frequency (f0) of the fundamental wave component of aforementioned AC power supply (6); and the impedance characteristic (Z) of Z2 in regard to the frequency has the aforementioned frequency (f0) of the fundamental wave component to be between, a frequency (fMAX) that has its local maximum (ZMAX) nearest to aforementioned frequency (f0) of the fundamental wave component, and a frequency (fMIN) that has its local minimum (ZMin) nearest to the frequency (f0) of the fundamental wave component. Z1 indicates that the coupling coefficient (k) between aforementioned primary winding (101) and aforementioned secondary winding (201) is a prescribed value (0.3), and that it is an impedance of just the primary side (Z1) as seen from the output side of aforementioned AC power supply (6); and Z2 indicates that the coupling coefficient (k) between aforementioned primary winding (101) and aforementioned secondary winding (201) is the aforementioned prescribed value (0.3), and that it is an impedance of just the secondary side (Z2) as seen from the side of a load (72) to be connected to aforementioned secondary winding (201).
US08716972B2 Motor control apparatus and method for controlling motor
A motor control apparatus includes a power converter, a speed controller, and a stop position controller. The power converter outputs a current to drive a motor based on a torque command. The speed controller generates the torque command based on an error between a speed command of the motor and a speed of the motor. The stop position controller calculates an acceleration command to output a predetermined torque after detection of a reference position per revolution of a position detector for a first time during speed control of the motor, generates a torque feed-forward command based on the acceleration command, generates a position command based on the acceleration command, and generates the speed command based on an error between the position command and the motor position to execute position control of the motor.
US08716969B2 Trash can with power operated lid
A trash can with a power operated lid can include a sensor assembly and a lifting mechanism. The sensor assembly can include at least one light emitter and at least one light receiver, the viewing area of the at least one light receiver being limited in size. The lifting mechanism can include a controller, a drive motor, and a lifting member. The trash can with power operated lid can further include at least one position sensor for detecting the position of the lid.
US08716966B2 Rotary electric machine for vehicles
In a vehicular rotary electric machine, a switching section includes a bridge circuit having plurality of upper arms and plurality of lower arms. The arms include switching elements. A diode is connected in parallel to each switching element. One end of the switching element of each of the upper arms is connected to a positive terminal of a battery and one end of the switching element of each of the lower arms is connected to a negative terminal of the battery via a vehicle body. The switching section rectifies induced phase voltage of an armature winding. A section sets ON-timing of the switching elements. A section sets OFF-timing of the switching elements. When the switching element of each lower arm is OFF, a detector detects an energization period in which current flows to the diode. A calculator calculates a rotation frequency based on the detected energization period.
US08716959B2 Hall-effect based linear motor controller
A linear motion control device for use in a linear control system is presented. The linear motion control device includes a coil driver to drive a coil that, when driven, effects a linear movement by a motion device having a magnet. The linear motion control device also includes a magnetic field sensor to detect a magnetic field associated with the linear movement and an interface to connect an output of the magnetic field sensor and an input of the coil driver to an external controller. The interface includes a feedback loop to relate the magnetic field sensor output signal to the coil driver input.
US08716958B2 Microwave device for accelerating electrons
A microwave device for accelerating electrons includes an electron gun providing an electron beam along an axis in a microwave structure for accelerating the electrons of the beam, an input for the electron beam, an output for accelerated electrons, and a series of coupled cavities along said axis, of central resonant frequency, an input for a microwave signal for excitation of the microwave structure by one of the cavities, a radiofrequency generator providing the excitation microwave signal to the acceleration microwave structure, and a central unit controlling the variation of energy of the electrons at the output of the microwave structure. The radiofrequency generator comprises a frequency control input for changing the frequency of the excitation microwave signal around the central resonant frequency, the change producing a variation of the energy of the accelerated electrons of the beam at the output of the microwave structure.
US08716953B2 Mechanisms for light management
Mechanisms for light management include a light emitting diode (LED) light bulb. The LED light bulb includes multiple light emitting diodes (LEDs) configured for illumination in the LED light bulb and includes a battery. A base is configured to fit a standard socket designed for an incandescent light bulb, and the base is configured to operatively connect to an electrical power source. A module is operative to detect a residual voltage of the power source when a control for powering the LED light bulb is powered off. The module is configured to determine that a power outage occurred and operative to switch to battery power from the battery in response to not detecting the residual voltage of the power source.
US08716952B2 Lighting device having first, second and third groups of solid state light emitters, and lighting arrangement
A lighting device comprising first, second and third groups of solid state light emitters, the first group emitting light having a dominant wavelength of 430 to 490 nm, the second group at 525 to 575 (in some devices 540 to 575 nm), the third group at 610 to 640 nm. In some devices, wavelength of light from emitters in first and second groups, and light from second and third groups, differs by at least 70 nm. Some devices emit light having CRI Ra of at least 70 when first, second and third groups of emitters are illuminated. Also, a lighting arrangement comprising first, second and third groups as above, in addition to a fourth emitter emitting light of dominant wavelength outside the ranges for the first, second and third groups, and not more than 10 nm different from a dominant wavelength of a color on an item to be illuminated.
US08716950B2 Method and circuit for catching excess current
Data may be encoded onto a direct current power line by modulating the current on that direct current power line. One method of modulating the current is by placing an inductor on the power line and then using a controlled transistor that turns on and turns off. The inductor will ensure that current keeps flowing but the transistor will induce changes in the current pattern. The excess current from when transistor is turned off must be diverted. Furthermore, to create symmetrical current changes, the inductor should be reverse biased. Thus, a circuit is created that sinks the excess current from when the transistor is turned off and used to reverse bias the inductor.
US08716949B2 Lighting device for solid-state light source and illumination apparatus using same
A lighting device for lighting a solid-state light source includes: a DC power circuit unit for converting a power of an input DC power source using a switching element and flowing a current through a solid-state light source; and a control unit for performing a first switching control in which the switching element is turned on/off at a first high frequency and a second switching control in which an ON/OFF operation of the switching element is intermittently stopped at a second frequency lower than the first frequency of the first switching control. When the current flowing through the solid-state light source is changed, the second frequency is varied.
US08716943B2 Light-emitting device and lighting apparatus provided with the same
According to one embodiment, a light-emitting device includes a substrate including an insulating surface, a plurality of light-emitting elements mounted on the surface of the substrate and electrically connected to each other, a positive power feeding conductor and a negative power feeding conductor mounted on the surface of the substrate to feed power to the light-emitting elements, lead-out terminals leading from the power feeding conductors, to the outside of an mounting area of the light-emitting elements, and an anti-noise part connected to the lead-out terminals and arranged outside the mounting area.
US08716939B2 Plasma ignition system, plasma ignition method, and plasma generating apparatus
Provided is a plasma ignition technique allowing easy and reliable ignition and reignition of plasma without monitoring or manual handling. A plasma ignition system according to this technique is provided with a radio-frequency power supply configured to supply a predetermined high frequency signal to an applied electrode for generating plasma; a matching device configured to match impedance on a side of the radio-frequency power supply and impedance on a side of the applied electrode; a forward wave/reflected wave detector configured to detect a forward wave and a reflected wave of the high frequency signal; a high-voltage generator configured to generate a predetermined high voltage; and a controller configured to superimpose the high voltage on the high frequency signal when a ratio of the reflected wave to the forward wave is greater than a first threshold value.
US08716938B2 Thermionic emission device
A thermionic emission device includes an insulating substrate, a patterned carbon nanotube film structure, a positive electrode and a negative electrode. The insulating substrate includes a surface. The surface includes an edge. The patterned carbon nanotube film structure is partially arranged on the surface of the insulating substrate. The patterned carbon nanotube film structure includes two strip-shaped arms joined at one end to form a tip portion protruded from the edge of the surface of the insulating substrate and suspended. The patterned carbon nanotube film structure includes a number of carbon nanotubes parallel to the surface of the insulating substrate. The patterned carbon nanotube film structure is connected between the positive electrode and the negative electrode in series.
US08716934B2 Short arc discharge lamp
Disclosed herein is a short arc discharge lamp which has a cathode electrode structure formed by solid-phase bonding a tip part made of thoriated tungsten to a body part made of tungsten. In the present invention, thorium can be reliably diffused onto the surface of the cathode electrode over a long period of time without stagnation of reduction of thorium oxide in the tip part. Therefore, satisfactory emission characteristics can be provided, whereby the arc stability is more reliable. The cathode electrode of the present invention is characterized in that potassium concentration of the body part is higher than potassium concentration of the tip part.
US08716932B2 Displays with minimized borders
An electronic device may be provided with a display having a flexible substrate with bent edges. The flexible substrate may have a planar active region that includes an array of light-emitting elements such as organic light-emitting diodes with associated control lines. The flexible substrate may also have inactive regions that lie outside of the active region. The bent edges may be formed from portions of the flexible substrate in the inactive regions. Traces for distributing control signals to the control lines in the active region may be formed in the inactive regions. Corner openings may be formed at the corners of the flexible substrate to accommodate bending of the flexible substrate in the inactive regions. A jumper or a portion of the flexible substrate that lies outside of a corner opening may be used to convey signals between traces on adjoining inactive regions.
US08716929B2 Organic electroluminescent device
An organic electroluminescent device including a first red sub-pixel region, a first green sub-pixel region and a deep blue sub-pixel region in a first pixel region; and a second red sub-pixel region, a second green sub-pixel region and a sky blue sub-pixel region in a second pixel region adjacent to the first pixel region, wherein each of the first and second red sub-pixel regions includes a first electrode, a red organic emission material pattern and a second electrode, each of the first and second green sub-pixel regions includes the first electrode, a green organic emission material pattern and the second electrode, wherein the deep blue sub-pixel region includes the first electrode, a deep blue organic emission material pattern and the second electrode, and the sky blue sub-pixel region includes the first electrode, a sky blue organic emission material pattern and the second electrode, and wherein an unit pixel displaying an image includes at least one of the deep blue sub-pixel region and the sky blue sub-pixel region with the second red sub-pixel region and the second green sub-pixel region.
US08716927B2 Display panel and system for displaying images utilizing the same
An embodiment of the invention provides a display panel, which includes a substrate having a pixel region and a peripheral region, a control element overlying the pixel region of the substrate, a conducting layer overlying the substrate in the peripheral region, a first insulating layer overlying the conducting layer in the peripheral region, wherein a ratio between an area of the first insulating layer and an area of the conducting layer in the peripheral region is between about 0.27 and 0.99, a lower electrode layer overlying the first insulating layer, and a second insulating layer overlying the lower electrode layer.
US08716926B2 Backlight unit using electron emission elements and a display apparatus having the same
A backlight unit includes a first substrate including an anode electrode; and a second substrate including a cathode electrode and an electron emission element, wherein the cathode electrode includes a terminal portion and at least one electrode strip extending from the terminal portion, and the electrode strip includes an electron emission portion on which the electron emission element is mounted and a junction portion which is disposed between the terminal portion and the electron emission portion, and wherein the closer the junction portion is to the terminal portion the greater the width of the junction portion is.
US08716925B2 Adjustable perveance electron gun header
In an electron gun for use in a TWT, klystron, linear accelerator or other electron device, an electron gun header assembly and an input body assembly are coupled using a flexible bellows that allows the distance between the cathode and anode to be varied. As such, the perveance of the electron gun can be tuned, and the cathode magnetic field optimized for efficient operation. In addition, an external magnetic shield is adapted to be translated along the axial dimension of the electron gun to further optimize the cathode magnetic field and focusing characteristics to achieve improved electron gun performance.
US08716923B2 Spark plug assembly
A spark plug assembly has a spark plug with an inner conductor, an outer conductor and an intervening insulator. A quick-change adapter is receivable in the spark plug hole of an internal combustion engine, and the spark plug is removably received in the adapter. Gas seal rings may be provided about the spark plug outer surface. Indexing marks may be provided on the adapter and the spark plug to angularly align the spark plug conductor gap to a desired angular position. The spark plug may be formed with an extension.
US08716919B2 Drive apparatus
A drive apparatus according to an embodiment includes: a movable unit configured to include a first sliding surface, and slide along the first sliding surface; a vibration generating unit configured to generate vibrations; a vibration transmitting unit configured to include a second sliding surface in contact with the first sliding surface of the movable unit, and transmit the vibrations generated by the vibration generating unit to the movable unit via the first and second sliding surfaces; a pre-pressure applying unit configured to apply pre-pressure to the movable unit via the vibration transmitting unit; and a driving force generating unit configure to generate a driving force for driving the movable unit in a predetermined direction, the driving force being greater than a friction force between the first sliding surface and the second sliding surface when the vibrations are being transmitted to the vibration transmitting unit, the driving force being smaller than the friction force when the vibrations are not being transmitted to the vibration transmitting unit.
US08716918B2 Drive circuit and physical quantity measuring device
In order for keeping the amplitude of the excitation current of a vibrator constant irrespective not only of the temperature variation but also of the manufacturing variation and the variation in frequency, a comparison control circuit for controlling the amplitude of the drive signal for exciting the vibrator includes a comparative voltage supply circuit for supplying the comparative voltage, and the comparative voltage supply circuit generates the comparative voltage with a constant current source and a second resistor made of a material the same as a material of a first resistor included in a current-voltage conversion circuit.
US08716916B2 Vibration generator, vibration generation device, and electronic equipment and communication device provided with vibration generation device
A vibration power generator including a first substrate; first electrodes disposed over one surface of the first substrate; a second substrate spaced from the first substrate and opposed to the one surface of the first substrate; and second electrodes disposed over one surface of the second substrate so as to be opposed to the first electrodes, wherein one of the first and second electrodes includes a film holding a charge; one of the first and second substrates is a vibratory substrate; and an overlapped area between the first and second electrodes becomes minimum and then maximum, or becomes maximum and minimum, and an electrostatic capacity Cp formed between the first and second electrodes when the overlapped area becomes maximum changes, and the change of Cp comprises an increase of Cp, while the vibratory substrate is displaced from the vibration center to the vibration end.
US08716914B2 Stator of vehicle AC generator and method for manufacturing the same
In a vehicle AC generator, a stator core (42) is formed by laminating thin steel sheets, the stator core (42) being provided with a plurality of slot portions (43) which accommodate a stator winding (41) and tooth portions (44) which define adjacent ones of the slot portions; the stator winding (41) is disposed in the slot portions to constitute a stator (4); the stator core (42) is filled with varnish (45) between laminates of each tooth (44) at least in an inner diameter end surface region which faces the rotor (3) and is coated with epoxy resin varnish (46) on the tooth surface of the inner diameter end surface region to form an anti-rust film.
US08716909B2 Robot with heat dissipating stator
A substrate transport apparatus including a drive section and a first movable arm assembly. The drive section includes a first motor. The first motor includes a stator and a passive rotor. The first movable arm assembly is connected to the first motor. The substrate transport apparatus is configured for the first movable arm assembly to be positionable in a vacuum chamber with the passive rotor being in communication with an environment inside the vacuum chamber.
US08716902B2 Inductively coupled data and power transfer system and apparatus
The present invention provides a system and apparatus for transferring electronic data and/or power from one station to another by means of a transportable pod comprising a solid state memory device and further provided with an inductively linked, electrically insulated connector. The transportable pod comprises a battery which is used to power a remote host docking station, which may be used in an underwater environment for the collection of subsea data. The transportable pod can be transferred alternately from a home docking station, where it is charged up, and where it's stored data is uploaded and to a remote host docking station where is provides power, and where it collects and stores data collected by the remote host docking station.
US08716898B1 Tunable power distribution network and method of use thereof
An improved power distribution network comprises a substrate, an integrated circuit mounted on the substrate, a first tunable decoupling capacitor mounted on the substrate, and a second tunable decoupling capacitor formed in the integrated circuit. The power supply pin is connected to both the first and second capacitors by a low frequency path and a DC path, respectively, and the first and second capacitors are connected by a high frequency path.
US08716895B2 Power supply device, operation method of power supply device, electronic apparatus, and operation method of electronic apparatus
A power supply device that switches one of a first power supply, a second power supply, and a third power supply, all of which supply power to an auxiliary device, to a transfer gate in a CMOS image sensor having a photodiode and outputs the corresponding power to the transfer gate is disclosed. The device includes: a first transistor driven by the second power supply and outputting power of the second power supply to the transfer gate; a second transistor driven by the second power supply and outputting power of the first power supply to the transfer gate; a third transistor driven by the third power supply and outputting power of the third power supply to the transfer gate; and a fourth transistor located before the second transistor, driven by the first power supply, and outputting power of the first power supply to a source of the second transistor.
US08716891B2 Energy storage system connected to a grid and multiple power generation modules and method of controlling the same
A grid-connected energy storage system capable of increasing the efficiency of a converter and a method of controlling the system are disclosed. In one aspect, the system includes a plurality of converters for converting power generated by each of the plurality of power generation modules into DC power at a voltage level, a plurality of series switches connected to the plurality of power generation modules, and a plurality of parallel switches configured to selectively connect each of the power generation modules to each and every other of the power generation modules. The system also includes a controller configured to control the switches in order to selectively connect each of the power generation modules to at least one selected converter.
US08716890B1 Multiply-connected power processing
Various power processing systems are described that employ a multiply-connected velocity inhibiting circuit. At least one active circuit is employed to synthesize at least one passive lumped element in the multiply-connected velocity inhibiting circuit.
US08716887B2 Systems and apparatus for monitoring and selectively controlling a load in a power system
An electrical system includes at least one power port and at least one monitoring and control device that is coupled to the power port. The monitoring and control device includes a load control module configured to control an amount of electrical power transmitted to at least one electrical load. The load control module is further configured to receive a power control command from a power system and to transmit a power control acknowledgement to the power system.
US08716886B2 Circuit device and method of current limit-based disconnect detection
In a particular embodiment, a power sourcing equipment (PSE) device includes at least one network port adapted to couple to a powered device to provide power and optionally data to the powered device via a network cable. The PSE device further includes a current limiter circuit coupled to the at least one network port and having an adjustable threshold. The PSE device also includes a logic circuit coupled to the current limiter circuit and adapted to reduce the adjustable threshold of the current limiter circuit to have a threshold level that is below a nominal operating current level. After a period of time has elapsed during which the current limiter circuit is not activated, the logic circuit is adapted to determine that the powered device is disconnected from the at least one network port.
US08716884B2 Vehicle controller
There is provided a vehicle controller that is mounted in a box-shaped manner beneath the floor or on the roof of a vehicle so as to supply electric power to vehicle apparatuses. The vehicle controller is configured with a plurality of functional modules 4; each of the functional modules 4 has at one side thereof an interface side 22 in which a first interface region 5 where signal-line terminals are arranged and a second interface region 6 where power-line terminals are arranged are separated; in each of the interface sides 22, the first interface region 5 is disposed in the vicinity of one and the same end and the second interface region 6 is disposed in the vicinity of the other and the same end; the plurality of functional modules includes a monitoring circuit, an overvoltage protection circuit, and an inverter.
US08716882B2 Powerline communicated load control
A system for transmitting communication signals, the system comprising an injector circuit connected to a powered circuit conductor and configured to modulate a power signal with a direct current voltage offset, the direct current voltage offset being within a range that causes approximately 1 percent or less total harmonic distortion of the power signal; and a decoder connected to the powered circuit conductor and a load, the decoder configured to demodulate the direct current voltage offset to control the load. A method for transmitting communication signals, the method comprising modulating a power signal on a powered circuit conductor with a direct current voltage offset, the direct current voltage offset being within a range that causes approximately 1 percent or less total harmonic distortion of the power signal; and demodulating the direct current voltage offset to control a load.
US08716879B2 Energy recovery apparatus for a refrigeration system
An energy recovery apparatus for use in a refrigeration system, comprises an intake port, a nozzle, a turbine and a discharge port. The intake port is adapted to be in fluid communication with a condenser of a refrigeration system. The nozzle comprises a converging portion, a throat region and a diverging portion. The nozzle is configured to expand refrigerant discharged from the condenser and increase velocity of the refrigerant as it passes through the nozzle. The turbine is positioned relative to the nozzle and configured to be driven by refrigerant discharged from the nozzle. The discharge port is downstream of the turbine and is configured to be in fluid communication with an evaporator of the refrigeration system.
US08716877B2 Method and apparatus for harvesting energy from ankle motion
A method for harvesting energy from ankle motion includes coupling a generator module across an ankle joint, the generator module including a generator and an elastic member. The generator is affixed to the leg shank and at least one of the generator and the elastic member is continuously coupled to the foot across the ankle joint. Energy may be harvested in the elastic member while generating electricity with the generator from motion of the ankle joint. Alternatively, or in addition, electricity may be generated with the generator from energy harvested in the elastic member after the energy is harvested.
US08716875B2 Window ball grid array (BGA) semiconductor packages
A semiconductor package includes a substrate having a first surface, a second surface that is opposite to the first surface, and an opening formed between the first surface of the substrate and the second surface of the substrate. One or more bonding wires electrically couple a first surface of a semiconductor die included in the semiconductor package to the first surface of the substrate through an opening of the substrate. A first electrically insulative structure is disposed to substantially fill an area between the first surface of the semiconductor die, the second surface of the substrate, and one or more interconnect bumps that electrically couple the semiconductor die to the substrate. The first electrically insulative structure substantially encapsulates the one or more bonding wires and substantially fills the opening of the substrate.
US08716874B2 Semiconductor device having metal posts non-overlapping with other devices and layout method of semiconductor device
A semiconductor device that is resin-sealed in a wafer level after a rewiring layer forming process and a metal post forming process forming a metal post are performed on a semiconductor substrate of the semiconductor device includes devices formed on the semiconductor substrate. Further all of the devices are disposed in respective positions other than positions overlapping a peripheral border of the metal post when viewed from a top of the semiconductor substrate.
US08716872B2 Stacked semiconductor package including connections electrically connecting first and second semiconductor packages
A stacked semiconductor package has a first semiconductor package including a first package substrate and a first semiconductor chip mounted on the first package substrate, a second semiconductor package including a second package substrate and a second semiconductor chip mounted on the second package substrate, and a plurality of connections electrically connecting the first and second semiconductor packages. The connections are disposed on an outer region of the first package substrate outside the first semiconductor chip. The connections are disposed along opposite first longer sides and opposite shorter second sides of the first package substrate. The heights of those connections disposed along each longer first side gradually vary from a central to an outer region (i.e., the ends) of the longer first side.
US08716871B2 Big via structure
A semiconductor device that includes a first metal layer component formed over a substrate. The semiconductor device includes a via formed over the first metal layer component. The via has a recessed shape. The semiconductor device includes a second metal layer component formed over the via. The semiconductor device includes a first dielectric layer component formed over the substrate. The first dielectric layer component is located adjacent to, and partially over, the first metal layer component. The first dielectric layer component contains fluorine. The semiconductor device includes a second dielectric layer component formed over the first dielectric layer component. The first dielectric layer component and the second dielectric layer component are each located adjacent to the via. The second dielectric layer component is free of fluorine.
US08716870B2 Direct write interconnections and method of manufacturing thereof
A semiconductor device package having direct write interconnections and method of manufacturing thereof is disclosed. A device package is formed by providing a substrate structure, attaching at least one device to the substrate structure that each include a substrate and one or more connection pads formed on the substrate, depositing a dielectric layer over the at least one device and onto the substrate structure by way of a direct write application, the dielectric layer including vias formed therethrough, and forming an interconnect structure on the dielectric layer that is electrically coupled to the connection pads of the at least one device, the interconnect structure extending through the vias in the dielectric layer so as to be connected to the connection pads.
US08716868B2 Semiconductor module for stacking and stacked semiconductor module
A pad (15) is provided on a surface connecting a first substrate (11) of a lower layer module with an upper layer module, the pad is partially covered by an insulating film (20) to form an opening section (3) exposing the pad (15), a first connection terminal (2) is formed on the lower surface of the first substrate (11) of the lower layer module, the planar shape of the opening section (3) is different from the planar shape of the first connection terminal (2), the outer shape of the opening section (3) is larger than the first connection terminal (2), and in a transmissive inspection from above, the shape of the lower end of a second connection terminal (30) spreading in the opening section (3) is not concealed by the other terminal. This configuration enables easy and reliable determination of whether bonding sections are satisfactory by a non-destructive inspection.
US08716859B2 Enhanced flip chip package
A flip chip package structure is proposed in which a redistribution layer (RDL) is disposed on a surface of both a semiconductor chip and one or more lateral extensions of the semiconductor chip surface. The lateral extensions may be made using, e.g., a reconstituted wafer to implement a fanout region lateral to one or more sides of the semiconductor chip. One or more electrical connectors such as solder bumps or copper cylinders may be applied to the RDL, and an interposer such as a PCB interposer may be connected to the electrical connectors. In this way, a relatively tight semiconductor pad pitch may be accommodated and translated to an appropriate circuit board pitch without necessarily requiring a silicon or glass interposer.
US08716857B2 Split loop cut pattern for spacer process
A semiconductor fabrication technique cuts loops formed in a spacer pattern. The spacer pattern is a split loop pattern which generally includes a symmetric arrangement of one or more loops in each of four quadrants which are defines with respect to a reference point. The loops can be peaks or trenches. Each quadrant can include one loop, or multiple nested loops. Further, the space pattern includes a single cross, or multiple nested crosses, which extend between the loops. A cut out area is defined which extends outward from the reference point to closed ends of the loops, also encompassing a central portion of the cross. When a metal wiring layer pattern is formed using the spacer pattern with the cut out area, metal wiring is excluded from the cut out area. The loop ends in the metal wiring layer are broken and can be used as independent active lines.
US08716852B2 Micro-electro mechanical systems (MEMS) having outgasing prevention structures and methods of forming the same
A device includes a capping substrate bonded with a substrate structure. The substrate structure includes an integrated circuit structure. The integrated circuit structure includes a top metallic layer disposed on an outgasing prevention structure. At least one micro-electro mechanical system (MEMS) device is disposed over the top metallic layer and the outgasing prevention structure.
US08716851B2 Continuously referencing signals over multiple layers in laminate packages
A mechanism for continuously referencing signals over multiple layers in laminate packages provides a continuous path for signals from one layer to another while using the ideal voltage reference for all areas of the package and still avoiding discontinuities in the voltage reference. A reference plane adjustment engine analyzes a package design and identifies an ideal top plane for all areas of the package, including areas under particular chip die(s) and areas that are not under a chip die. The reference plane adjustment engine then modifies the package design to reposition ground planes, source voltage planes, signal planes, and vias between layers to maintain a continuous voltage reference regardless of the top layer. The reference plane adjustment engine provides the resulting mixed voltage plane package design to a design analysis engine. A package fabrication system fabricates the package.
US08716850B2 Semiconductor device and method for manufacturing the same
An object is to realize a hermetically sealed package which ensures long-term airtightness inside the package by sealing using a substrate, or a sealing structure for reducing destruction caused by pressure from the outside. A frame of a semiconductor material is provided over a first substrate, which is bonded to a second substrate having a semiconductor element so that the semiconductor element is located inside the frame between the first substrate and the second substrate. The frame may be formed using, as frame members, two L-shaped semiconductor members in combination or four or more stick semiconductor members in combination.
US08716845B2 Lead frame strip for reduced mold sticking during degating
A lead frame strip includes an array of sites arranged in at least one row connected to two exterior side rails which traverse the lead frame strip on two opposite sides. Each of the sites is further connected to the two exterior side rails by subrails which extend between the two exterior side rails. Interior side rails extend between the subrails having a length dimension oriented along a first direction. The interior side rails include at least one punch degating aperture having an aperture length oriented along the first direction, wherein a total of the aperture length along the interior side rails is greater than or equal to the die pad length.
US08716843B2 Microelectronic chip, component containing such a chip and manufacturing method
Microelectronic chip including a semiconductor substrate; at least one area of its surface which is suitable to be electrically connected to a metal frame designed to accommodate the chip; at least one interconnect area formed by a copper-based conductive layer and comprising a connecting device, the interconnect area being connected to the area by a conductor, wherein the area is formed by a layer forming a copper diffusion barrier inserted between interconnect area and the substrate.
US08716840B2 Backside thermal patterning of buried oxide (BOX)
The dominant source of thermal resistance for silicon photonic devices patterned on SOI wafers is the buried oxide layer. To ensure efficient thermally driven silicon devices there is a need for a large thermal resistance. This is in contrast to temperature sensitive components need to have low thermal resistance in order to reduce their temperature to ensure good performance. Embodiments comprise etching the back of an SOI wafer to expose the buried oxide layer and depositing an additional layer of silicon oxide to increase the local thermal resistance. Thus, embodiments provide the ability to tailor the thermal resistance across the wafer or die depending on the device being fabricated.
US08716836B2 Semiconductor wafer, semiconductor wafer manufacturing method, and electronic device
A high-quality GaAs-type crystal thin film using an inexpensive Si wafer with good thermal release characteristics is achieved. Provided is a semiconductor wafer comprising an Si wafer; an inhibiting layer that is formed on the wafer and that inhibits crystal growth, the inhibiting layer including a covering region that covers a portion of the wafer and an open region that does not cover a portion of the wafer within the covering region; a Ge layer that is crystal-grown in the open region; and a functional layer that is crystal-grown on the Ge layer. The Ge layer may be formed by annealing with a temperature and duration that enables movement of crystal defects, and the annealing is repeated a plurality of times.
US08716834B2 Semiconductor device including antenna
A semiconductor device that can prevent reduction in the amplitude of electromagnetic waves transmitted from a reader/writer, and can prevent heating of an element forming layer due to a change in a magnetic field. The semiconductor device of the invention has an element forming layer formed over a substrate, and an antenna connected to the element forming layer. The element forming layer has at least wires such as a power supply wire and a ground wire that are arranged in a non-circular shape. The element forming layer and the antenna may be provided so as to overlap each other at least partially. The antenna may be provided above or below the element forming layer.
US08716832B2 Semiconductor structure including guard ring
One or more embodiments related to a semiconductor structure, comprising: a conductive feature; an outer guard ring; and an inner guard ring between the outer guard ring and the conductive feature, the inner guard ring being electrically coupled to the conductive feature.
US08716814B2 Wireless processor, wireless memory, information system, and semiconductor device
The invention provides a processor obtained by forming a high functional integrated circuit using a polycrystalline semiconductor over a substrate which is sensitive to heat, such as a plastic substrate or a plastic film substrate. Moreover, the invention provides a wireless processor, a wireless memory, and an information processing system thereof which transmit and receive power or signals wirelessly. According to the invention, an information processing system includes an element forming region including a transistor which has at least a channel forming region formed of a semiconductor film separated into islands with a thickness of 10 to 200 nm, and an antenna. The transistor is fixed on a flexible substrate. The wireless processor in which a high functional integrated circuit including the element forming region is formed and the semiconductor device transmit and receive data through the antenna.
US08716813B2 Scaled equivalent oxide thickness for field effect transistor devices
A field effect transistor device includes a first gate stack portion including a dielectric layer disposed on a substrate, a first TiN layer disposed on the dielectric layer, a metallic layer disposed on the dielectric layer, and a second TiN layer disposed on the metallic layer, a first source region disposed adjacent to the first gate stack portion, and a first drain region disposed adjacent to the first gate stack portion.
US08716812B2 Interfacial layer regrowth control in high-K gate structure for field effect transistor
A field effect transistor having a gate structure comprising a high-K dielectric layer, a gate electrode located on the high-K dielectric layer, and an interfacial layer located in between the high-K dielectric layer and a channel region of the field effect transistor. The interfacial layer comprises a layer of SiO2 containing a regrowth inhibiting agent. A method of forming the gate structure includes forming a gate stack comprising, in order: a SiO2 layer adjacent a channel region of the field effect transistor; a high-K dielectric layer on the SiO2 layer; and a gate electrode on the high-K dielectric layer. The method also includes introducing a regrowth inhibiting agent into the SiO2 layer and then annealing the gate structure. The presence of the regrowth inhibiting agent in the SiO2 interfacial layer inhibits regrowth of the SiO2 layer into the channel region during the annealing step.
US08716811B2 Semiconductor device
A semiconductor device includes a first conduction-type semiconductor substrate, a first semiconductor region of a first conduction-type formed on the semiconductor substrate, a second semiconductor region of a second conduction-type formed on a surface of the first semiconductor region, a third semiconductor region of the second conduction-type formed to be separated from the second semiconductor region on the surface of the first semiconductor region, a fourth semiconductor region of the second conduction-type formed to be separated from the second semiconductor region and the third semiconductor region on the surface of the first semiconductor region, and a first electrode connected to the second semiconductor region and the third semiconductor region.
US08716805B2 CMOS integrated circuits with bonded layers containing functional electronic devices
A complementary metal oxide semiconductor (CMOS) circuit having integrated functional devices such as nanowires, carbon nanotubes, magnetic memory cells, phase change memory cells, ferroelectric memory cells or the like. The functional devices are integrated with the CMOS circuit. The functional devices are bonded (e.g. by direct bonding, anodic bonding, or diffusion bonding) to a top surface of the CMOS circuit. The functional devices are fabricated and processed on a carrier wafer, and an attachment layer (e.g. SiO2) is deposited over the functional devices. Then, the CMOS circuit and attachment layer are bonded. The carrier wafer is removed (e.g. by etching). The functional devices remain attached to the CMOS circuit via the attachment layer. Apertures are etched through the attachment layer to provide a path for electrical connections between the CMOS circuit and the functional devices.
US08716801B2 Metal oxide semiconductor device
Provided is a metal oxide semiconductor device, including a substrate, a gate, a first-type first heavily doped region, a first-type drift region, a second-type first heavily doped region, a contact, a first electrode, and a second electrode. The gate is disposed on the substrate. The first-type first heavily doped region is disposed in the substrate at a side of the gate. The first-type drift region is disposed in the substrate at another side of the gate. The second-type first heavily doped region is disposed in the first-type drift region. The contact is electrically connected to the second-type first heavily doped region. The contact is the closest contact to the gate on the first-type drift region. The first electrode is electrically connected to the contact, and the second electrode is electrically connected to the first-type first heavily doped region and the gate.
US08716796B2 Semiconductor device
A semiconductor device includes a second conductive-type deep well configured above a substrate. The deep well includes an ion implantation region and a diffusion region. A first conductive-type first well is formed in the diffusion region. A gate electrode extends over portions of the ion implantation region and of the diffusion region, and partially overlaps the first well. The ion implantation region has a uniform impurity concentration whereas the impurity concentration of the diffusion region varies from being the highest concentration at the boundary interface between the ion implantation region and the diffusion region to being the lowest at the portion of the diffusion region that is the farthest away from the boundary interface.
US08716795B2 Fabrication of lateral double-diffused metal oxide semiconductor (LDMOS) devices
Methods of making, structures, devices, and/or applications for lateral double-diffused metal oxide semiconductor (LDMOS) transistors are disclosed. In one embodiment, a method of fabricating an LDMOS transistor with source, drain, and gate regions on a substrate, can include: forming p-type and n-type buried layer (PBL, NBL) regions; growing an epitaxial (N-EPI) layer on the NBL/PBL regions; forming a p-doped deep p-well (DPW) region on the PBL region; forming a well region in the N-EPI layer; forming a doped body region; forming an active area and a field oxide (FOX) region, and forming a drain oxide between the source and drain regions of the LDMOS transistor; forming a gate oxide adjacent to the source and drain regions, and forming a gate on the gate oxide and a portion of the drain oxide; and forming a doped drain region, and first and second doped source regions.
US08716793B2 Lateral double diffused metal oxide semiconductor device and method for manufacturing the same
Disclosed are an LDMOS device and a method for manufacturing the same capable of decreasing the concentration of a drift region between a source finger tip and a drain, thereby increasing a breakdown voltage. An LDMOS device includes a gate which is formed on a substrate, a source and a drain which are separately arranged on both sides of the substrate with the gate interposed therebetween, a field oxide film which is formed to have a step between the gate and the drain, a drift region which is formed of first condition type impurity ions between the gate and the drain on the substrate, and at least one internal field ring which is formed inside the drift region and formed by selectively ion-implanting second conduction type impurity ions in accordance with the step of the field oxide film.
US08716791B1 LDMOS with corrugated drift region
Semiconductor devices, such as LDMOS devices, are described that include a plurality of trench regions formed in an extended drain region of the devices. In one or more implementations, the semiconductor devices include a substrate having an extended drain region, a source region, and a drain region, all of the first conductivity type, formed proximate to a surface of the substrate. A gate is positioned over the surface and between the source region and the drain region. The gate is configured to receive a voltage so that a conduction region may be formed at least partially below the gate to allow charge carriers (e.g., majority carriers) to travel between the source region and the drain region. A plurality of trench regions are formed within the extended drain region that are configured to increase resistivity within the extended drain region when charge carriers travel between the source region and the drain region.
US08716781B2 Logic transistor and non-volatile memory cell integration
A first conductive layer and an underlying charge storage layer are patterned to form a control gate in an NVM region. A first dielectric layer and barrier layer are formed over the control gate. A sacrificial layer is formed over the barrier layer and planarized. A first patterned masking layer is formed over the sacrificial layer and control gate in the NVM region which defines a select gate location laterally adjacent the control gate in the NVM region. A second masking layer is formed in the logic region which defines a logic gate location. Exposed portions of the sacrificial layer are removed such that a first portion remains at the select gate location. A second dielectric layer is formed over the first portion and planarized to expose the first portion. The first portion is removed to result in an opening at the select gate location which exposes the barrier layer.
US08716780B2 Three-dimensional memory array stacking structure
A memory device includes a planar substrate, a plurality of horizontal conductive planes above the planar substrate, and a plurality of horizontal insulating layers interleaved with the plurality of horizontal conductive planes. An array of vertical conductive columns, perpendicular to the pluralities of conductive planes and insulating layers, passes through apertures in the pluralities of conductive planes and insulating layers. The memory device includes a plurality of programmable memory elements, each of which couples one of the horizontal conductive planes to a respective vertical conductive column.
US08716779B2 Flash memory device and mask for fabricating the same
A flash memory device includes an active region, drain contacts, a source contact line, and source contacts. The active regions are formed on a substrate extend at least from a source region to a drain region of the substrate. The drain contacts are formed over the active regions in the drain region. The source contact line is formed in the source region of the semiconductor substrate. The source contact line intersects the active regions and is continuously line-shaped. The source contact line includes source contacts formed at locations where the source contact line and the active regions intersect. The source contacts are zigzag-shaped and are separated from corresponding drain contacts by a given distance.
US08716778B2 Metal-insulator-metal capacitors
Metal-insulator-metal capacitors are provided that are formed in integrated circuit dielectric stacks. A line-plate-line capacitor is provided that alternates layers that contain metal plates with layers that contain straight or angled parallel lines of alternating polarity. A segmented-plate capacitor is provided that has metal plates that alternate in polarity both within a layer and between layers. The line-plate-line and segmented-plate capacitors may exhibit a reduced parasitic inductive coupling. The capacitances of the line-plate-line capacitor and the metal-insulator-metal capacitor may have an enhanced contribution from an interlayer capacitance component with a vertical electric field than a horizontal intralayer capacitance component with a horizontal electric field.
US08716777B2 Semiconductor device and method for manufacturing the same
A method for forming a semiconductor device includes forming a sealing insulation film over a semiconductor substrate including a device isolation film and an active region, forming a bit line contact plug that protrudes from an upper part of the sealing insulation film and is coupled to the active region, forming a spacer over a sidewall of the protruded bit line contact plug, and forming a bit line coupled to an upper part of the bit line contact plug.
US08716776B2 Method of fabricating isolated capacitors and structure thereof
A structure and method is provided for fabricating isolated capacitors. The method includes simultaneously forming a plurality of deep trenches and one or more isolation trenches surrounding a group or array of the plurality of deep trenches through a SOI and doped poly layer, to an underlying insulator layer. The method further includes lining the plurality of deep trenches and one or more isolation trenches with an insulator material. The method further includes filling the plurality of deep trenches and one or more isolation trenches with a conductive material on the insulator material. The deep trenches form deep trench capacitors and the one or more isolation trenches form one or more isolation plates that isolate at least one group or array of the deep trench capacitors from another group or array of the deep trench capacitors.
US08716763B2 Semiconductor structure and method for forming the same
A semiconductor structure and a method for forming the same are provided. The semiconductor structure includes a first doped region and a semiconductor region. The first doped region has a first type conductivity. The semiconductor region is in the first doped region. A source electrode and a drain electrode are respectively electrically connected to parts of the first doped region on opposite sides of the semiconductor region.
US08716762B2 Biosensor kit
Disclosed are: a biosensor kit in which a bionsensor utilizing a field effect transistor is not deteriorated during storage or transport; and a system for detecting a substance of interest, which is equipped with the biosensor chip. The biosensor kit comprises a biosensor chip which can measure a substance of interest quantitatively and a package which can hermetically seal the biosensor chip and is composed of a packaging material comprising a metal film. The biosensor chip can measure the substance quantitatively based on the value of a current generated in a field effect transistor when the substance is reacted with a molecule that can recognize the substance and is immobilized on a reaction field connected to the field effect transistor. The biosensor chip comprises the field effect transistor and a mounting substrate on which the field effect transistor is mounted.
US08716758B2 Thin film transistor and organic light-emitting display
A thin film transistor including: a substrate; an active layer formed over the substrate; a gate insulating layer formed over the active layer; a gate electrode formed over the gate insulating layer; an interlayer insulating layer formed over the gate electrode; and source and drain electrodes that contact the active layer via the interlayer insulating layer. The source and drain electrodes may have a structure including an aluminum (Al) layer, an aluminum-nickel alloy (AlNiX) layer, and an indium tin oxide (ITO) layer, which are sequentially stacked.
US08716756B2 Semiconductor device
A semiconductor device according to the present invention includes a substrate; a nitride semiconductor layer formed above the substrate and having a laminated structure including at least three layers; a heterojunction bipolar transistor formed in a region of the nitride semiconductor layer; and a field-effect transistor formed in a region of the nitride semiconductor layer, the region being different from the region in which the heterojunction bipolar transistor is formed.
US08716755B2 Semiconductor device and method for manufacturing the same
Compression strains are generated at an interface between the cap layer and the barrier layer and an interface between the channel layer and the buffer layer and a tensile strain is generated at an interface between the barrier layer and the channel layer. Therefore, negative charge is higher than positive charge at the interface between the cap layer and the barrier layer and the interface between the channel layer and the buffer layer, while positive charge is higher than negative charge at the interface between the barrier layer and the channel. The channel layer has a stacked layer structure of a first layer, a second layer, and a third layer. The second layer has a higher electron affinity than those of the first layer and the third layer.
US08716754B2 Nitride semiconductor device
The present invention relates to a nitride semiconductor device One aspect of the present invention provides a nitride semiconductor device including: a nitride semiconductor layer having a 2DEG channel; a source electrode in ohmic contact with the nitride semiconductor layer; a drain electrode in ohmic contact with the nitride semiconductor layer; a p-type nitride layer formed on the nitride semiconductor layer between the source and drain electrodes; an n-type nitride layer formed on the p-type nitride layer; and a gate electrode formed between the source and drain electrodes to be close to the source electrode and in contact with the n-type nitride layer so that a source-side sidewall thereof is aligned with source-side sidewalls of the p-type and n-type nitride layers.
US08716753B2 Nitride semiconductor material, semiconductor element, and manufacturing method thereof
The nitride semiconductor material according to the present invention includes a group III nitride semiconductor and a group IV nitride formed on the group III nitride semiconductor, where an interface between the group III nitride semiconductor and the group IV nitride has a regular atomic arrangement. Moreover, an arrangement of nitrogen atoms of the group IV nitride in the interface and an arrangement of group III atoms of the group III nitride semiconductor in the interface may be substantially identical.
US08716748B2 Semiconductor device and method of manufacturing the same, and power supply apparatus
A semiconductor device includes: a substrate; a semiconductor stacked structure, provided over the substrate, including an electron transit layer and an electron supply layer; a gate electrode, a source electrode, and a drain electrode provided over the semiconductor stacked structure; a gate pad, a source pad, and a drain pad provided over the gate electrode, the source electrode, and the drain electrode, and connected to the gate electrode, the source electrode, and the drain electrode, respectively; and a conductive layer provided under the gate pad, the source pad, and the drain pad, wherein a distance between the gate pad and the source pad is smaller than a distance between the gate pad and the drain pad.
US08716746B2 Semiconductor device
In a semiconductor device, an IGBT cell includes a trench passing through a base layer of a semiconductor substrate to a drift layer of the semiconductor substrate, a gate insulating film on an inner surface of the trench, a gate electrode on the gate insulating film, a first conductivity-type emitter region in a surface portion of the base layer, and a second conductivity-type first contact region in the surface portion of the base layer. The IGBT cell further includes a first conductivity-type floating layer disposed within the base layer to separate the base layer into a first portion including the emitter region and the first contact region and a second portion adjacent to the drift layer, and an interlayer insulating film disposed to cover an end of the gate electrode. A diode cell includes a second conductivity-type second contact region in the surface portion of the base layer.
US08716741B2 LED package and LED package mounting structure
A highly reliable LED package mounting structure which can realize improvement in solder fatigue life at low costs is provided. An LED package has a light-emitting surface which is perpendicular to a mounting surface of a circuit board, comprises connection terminal portions on the side face or on the side face and the bottom face of the package, and is joined with the circuit board by soldering via the connection terminal portion. Furthermore, the shape of the solder is optimized by defining the relative position relation between the end of an electrode on the central side of the LED package on the bottom face of an LED package body and the end of a component mounting pad on the circuit board.
US08716740B1 Electrode structure for an LED
An electrode structure for an LED includes a plurality of blind holes and a plurality of N-type metal electrodes. The LED comprises, in this order by stacking, an intrinsic semiconductor layer, an N-type semiconductor layer, a light emitting layer, a P-type semiconductor layer, a mirror layer, a buffer layer, a bonding layer, a permanent substrate and a P-type electrode. The blind holes are distributed in a pattern and run through the intrinsic semiconductor layer to reach the N-type semiconductor layer. The N-type metal electrodes respectively run through the blind holes to connect the N-type semiconductor layer. Through a 3D contact interface formed by the blind hole, not only contact impedance between the N-type metal electrode and the N-type semiconductor layer can be reduced, the N-type metal electrode also can be firmly held in the blind hole without peeling off.
US08716738B2 Semiconductor light-emitting device
A semiconductor light-emitting device includes a light emitting structure on a substrate. The light emitting structure includes a first conductive semiconductor layer, an active layer and a second conductive semiconductor layer. A plurality of transparent layers is disposed on the light emitting structure. A metal layer is disposed between the plurality of transparent layers. An electrode is electrically connected to the metal layer and contacts a portion of the metal layer.
US08716737B2 Die-bonded LED
An LED includes a first intermetallic layer, a first metal thin film layer, an LED chip, a substrate, a second metal thin film layer, and a second intermetallic layer. The first metal thin film layer is located on the first intermetallic layer. The LED chip is located on the first metal thin film layer. The second metal thin film layer is located on the substrate. The second intermetallic layer is located on the second metal thin film layer, and the first intermetallic layer is located on the second intermetallic layer. Materials of the first and the second metal thin film layer are selected from a group consisting of Au, Ag, Cu, and Ni. Materials of the intermetallic layers are selected from a group consisting of a Cu—In—Sn intermetallics, an Ni—In—Sn intermetallics, an Ni—Bi intermetallics, an Au—In intermetallics, an Ag—In intermetallics, an Ag—Sn intermetallics, and an Au—Bi intermetallics.
US08716733B2 Transfer sheet for phosphor layer and light-emitting device
A transfer sheet for a phosphor layer includes a release substrate, a phosphor layer formed on the release substrate, and an adhesive layer formed on the phosphor layer.
US08716730B2 LED module having a platform with a central recession
An LED module comprises a platform having a recession, wherein the recession presents a center section with a bottom and an enlarged section surrounding the center portion. An LED chip is arranged on the bottom of the center section. A bond wire leads from the LED chip to the bottom of the enlarged section in order to contact a first electrode of the LED chip. In one embodiment the bond wire is electrically connected to the back side of the platform by means of a through contact leading from the bottom of the enlarged section through the platform to the backside of the platform. In another embodiment a first conducting path leads from a first electrode of the LED chip across the side wall of the recession to the surface of the platform and from there across a lateral wall of the platform to the back side of the platform. A second conducting path, electrically isolated from the first conducting path, leads from a second electrode of the LED chip across the side wall of the recession to the to surface of the platform and from there across a lateral wall of the platform to the back side of the platform.
US08716728B2 Nitride semiconductor light-emitting diode device
A nitride semiconductor light-emitting diode element 1 includes a nitride semiconductor layer 12 having a bottom surface and an upper surface and containing a light emitting layer 12b inside, and a supporting substrate 11 made from a metal is bonded to the bottom surface of the nitride semiconductor layer 12. A light reflecting depression A1 to reflect light generated in the light emitting layer 12b is formed in the bottom surface of the nitride semiconductor layer 12. According to the nitride semiconductor light-emitting diode element 1, since the light generated from the light emitting layer 12b and propagated in the nitride semiconductor layer 12 in a layer direction is reflected by the light reflecting depression A1 and its travel direction is changed, the ratio of the light incident upon the upper surface of the nitride semiconductor layer 12 within a critical angle is increased. Thus, light extraction efficiency is improved as compared with a conventional nitride semiconductor light-emitting diode element.
US08716726B2 Organic light emitting illuminant, and device and method for the production thereof
A coating device for producing an organic light-emitting illuminant comprising mutually adjacent regions having in each case different emission colors, includes a vacuum chamber, a device for linearly transporting a substrate, and a plurality of coating sources and diaphragms, provides OLED structures which have an improved intensity of the light emission. The thicknesses of the hole transport, emission and electron transport layers in the mutually adjacent regions differ and are in each case set such that an optimum coupling-out for the light color emitted in the corresponding region is achievable.
US08716725B2 Package for multiple light emitting diodes
Substrates and packages for LED-based light devices can significantly improve thermal performance and provide separate electrical and thermal paths through the substrate. One substrate includes multiple electrically insulating base layers. On a top one of these layers are disposed top-side electrical contacts, including light device pads to accommodate a plurality of light devices. External electrical contacts are disposed on an exterior surface of the substrate. Electrical paths connect the top-side electrical contacts to the external electrical contacts. At least portions of some of the electrical paths are disposed between the electrically insulating base layers. The electrical paths can be arranged such that different subsets of the light device pads are addressable independently of each other. A heat dissipation plate can be formed on the bottom surface of a bottom one of the base layers.
US08716723B2 Reflective layer between light-emitting diodes
A system and method for manufacturing a light-generating device is described. A preferred embodiment comprises a plurality of LEDs formed on a substrate. Each LED preferably has spacers along the sidewalls of the LED, and a reflective surface is formed on the substrate between the LEDs. The reflective surface is preferably located lower than the active layer of the individual LEDs.
US08716721B2 Light emitting device and manufacturing method thereof
A light emitting device comprises a substrate having a plurality of light emitting elements mounted thereon; a side wall structure having a partition wall portion separating a plurality of light emitting areas that each include at least one of the light emitting elements; and encapsulating resin filled in the light emitting areas to bury the light emitting elements therein. The side wall structure is separated by a space from the substrate at, at least, the partition wall portion so as to be in noncontact with the substrate, and the encapsulating resin is formed so as to integrally, continuously fill the light emitting areas and the space without producing any interface therein.
US08716717B2 Semiconductor device and method for manufacturing the same
A RESURF layer including a plurality of P-type implantation layers having a low concentration of P-type impurity is formed adjacent to an active region. The RESURF layer includes a first RESURF layer, a second RESURF layer, a third RESURF layer, a fourth RESURF layer, and a fifth RESURF layer that are arranged sequentially from the P-type base side so as to surround the P-type base. The second RESURF layer is configured with small regions having an implantation amount equal to that of the first RESURF layer and small regions having an implantation amount equal to that of the third RESURF layer being alternately arranged in multiple. The fourth RESURF layer is configured with small regions having an implantation amount equal to that of the third RESURF layer and small regions having an implantation amount equal to that of the fifth RESURF layer being alternately arranged in multiple.
US08716716B2 Method and system for junction termination in GaN materials using conductivity modulation
A semiconductor structure includes a GaN substrate having a first surface and a second surface opposing the first surface. The GaN substrate is characterized by a first conductivity type and a first dopant concentration. The semiconductor structure also includes a first GaN epitaxial layer of the first conductivity type coupled to the second surface of the GaN substrate and a second GaN epitaxial layer of a second conductivity type coupled to the first GaN epitaxial layer. The second GaN epitaxial layer includes an active device region, a first junction termination region characterized by an implantation region having a first implantation profile, and a second junction termination region characterized by an implantation region having a second implantation profile.
US08716714B2 Display device having electrostatic discharge protection circuit and manufacturing method thereof
A method of manufacturing a display device including an electrostatic discharge protection circuit, the method including: forming an amorphous silicon layer on a substrate; crystallizing a partial region of the amorphous silicon layer into a polycrystalline silicon layer; and forming at least one transistor on the amorphous silicon layer that was not crystallized into the polycrystalline layer, wherein the electrostatic discharge protection circuit comprises the at least one transistor.
US08716712B2 Semiconductor device
An object of the invention is to improve the accuracy of light detection in a photosensor, and to increase the light-receiving area of the photosensor. The photosensor includes: a light-receiving element which converts light into an electric signal; a first transistor which transfers the electric signal; and a second transistor which amplifies the electric signal. The light-receiving element includes a silicon semiconductor, and the first transistor includes an oxide semiconductor. The light-receiving element is a lateral-junction photodiode, and an n-region or a p-region included in the light-receiving element overlaps with the first transistor.
US08716710B2 Thin-film transistor array substrate and method of fabricating the same
A thin-film transistor (TFT) array substrate comprises: a substrate; an active layer and a capacitor first electrode formed on the substrate; a gate insulating film formed on the substrate, the active layer and the capacitor first electrode; a gate electrode formed on the gate insulating film corresponding to the active layer and a capacitor second electrode formed on the gate insulating film corresponding to the capacitor first electrode; an interlayer insulating film formed on the gate insulating film, the gate electrode, and the capacitor second electrode; and a pixel electrode, a source electrode, and a drain electrode formed on the interlayer insulating film; wherein at least one of the source electrode and the drain electrode is formed on the pixel electrode. A method of fabricating the TFT array substrate is also disclosed.
US08716706B2 Charge injection and transport layers
Compositions for use in hole transporting layers (HTLs) or hole injection layers (HILs) are provided, as well as methods of making the compositions and devices fabricated from the compositions. OLED devices can be made. The compositions comprise at least one conductive conjugated polymer, at least one semiconducting matrix component that is different from the conductive conjugated polymer, and an optional dopant, and are substantially free of an insulating matrix component.
US08716705B2 Organic light emitting diode module
An organic light emitting diode module is provided and includes a substrate, a first electrode located on the substrate, a pair of second electrodes located on the substrate, a light emitting element located on the substrate, a first copper foil electrically connected to the first electrode, a pair of second copper foils respectively electrically connected to the second electrodes, and a cross connection conductor electrically connected to the second copper foils. The second electrodes are in an arrangement opposite to one another. The light emitting element includes a first electrode layer electrically connected to the first electrode, a second electrode layer located between the second electrodes and electrically connected to the second electrodes, and an organic light emitting layer located between the first and second electrode layers.
US08716703B2 Organic semiconductor transistor
Provided is an organic semiconductor transistor including plural electrodes, and an organic semiconductor layer containing at least one fluorene compound represented by the following formula (I): wherein R1 represents an alkyl group having from 1 to 8 carbon atoms; R2 and R3 each independently represent an alkyl group having from 1 to 8 carbon atoms, or an alkoxy group having from 1 to 8 carbon atoms; and n represents an integer of from 1 to 3.
US08716701B2 Method and apparatus for providing a charge blocking layer on an infrared up-conversion device
Embodiments of the invention are directed to an improved device for sensing infrared (IR) radiation with upconversion to provide an output of electromagnetic radiation having a shorter wavelength than the incident IR radiation, such as visible light. The device comprises an anode, a hole blocking layer to separate an IR sensing layer from the anode, an organic light emitting layer that is separated from the anode by the IR sensing layer, and a cathode. The hole blocking layer assures that when a potential is applied between the anode and the cathode the organic light emitting layer generates electromagnetic radiation only when the IR sensing layer is irradiated with IR radiation.
US08716699B2 Organic light-emitting diodes having white light emission
There is provided an organic light-emitting diode luminaire. The luminaire includes a first electrode, a second electrode, and an electroluminescent layer therebetween. The electroluminescent layer includes: a host material capable of electroluminescence having an emission color that is blue; and a dopant having an emission color that is red-orange. The additive mixing of the emitted colors results in an overall emission of white light.
US08716695B2 Compressive (PFET) and tensile (NFET) channel strain in nanowire FETs fabricated with a replacement gate process
A method of fabricating a FET device is provided which includes the following steps. Nanowires/pads are formed in a SOI layer over a BOX layer, wherein the nanowires are suspended over the BOX. A HSQ layer is deposited that surrounds the nanowires. A portion(s) of the HSQ layer that surround the nanowires are cross-linked, wherein the cross-linking causes the portion(s) of the HSQ layer to shrink thereby inducing strain in the nanowires. One or more gates are formed that retain the strain induced in the nanowires. A FET device is also provided wherein each of the nanowires has a first region(s) that is deformed such that a lattice constant in the first region(s) is less than a relaxed lattice constant of the nanowires and a second region(s) that is deformed such that a lattice constant in the second region(s) is greater than the relaxed lattice constant of the nanowires.
US08716694B2 Semiconductor light emitting device
A semiconductor light emitting device includes: n-type and p-type semiconductor layers; and an active layer disposed between the n-type and p-type semiconductor layers. The active layer has a structure in which a plurality of quantum well layers and a plurality of quantum barrier layers are alternately disposed, wherein the plurality of quantum well layers are made of AlxInyGa1-x-yN (0≦x<1, 0
US08716693B2 Light emitting device and light emitting device package for improving a light emission efficiency
A light emitting device, a method of manufacturing the same, a light emitting device package, and a lighting system are disclosed. The light emitting device may include a first conductive semiconductor layer, a second conductive semiconductor layer, and an active layer interposed between the first and second conductive semiconductor layers. The first conductive semiconductor layer, the active layer, and the second conductive semiconductor layer may include Al. The second conductive semiconductor layer may have Al content higher than Al content of the first conductive semiconductor layer. The first conductive semiconductor layer may have Al content higher than Al content of the active layer.
US08716685B1 Systems and methods for use in generating pulsed terahertz radiation
A terahertz generating assembly generally includes a light emitting device that is configured to generate at least one pulsed light beam. A first dispersion member is positioned proximate to the light emitting device, wherein the first dispersion member is configured to facilitate a temporal dispersion of the light beam. A second dispersion member is positioned proximate to the first dispersion member and to the light emitting device, wherein the second dispersion member is configured to facilitate a spatial dispersion of the light beam. A lens is positioned proximate to each of the first and second dispersion members, wherein the lens is configured to focus the temporal and spatial dispersions to produce at least one moving spot of light. At least one waveguide is positioned proximate to the lens, wherein the waveguide is configured to apply a biased voltage to the spot of light to generate pulsed terahertz radiation.
US08716672B2 Charged particle optical system, drawing apparatus, and method of manufacturing article
The present invention provides a charged particle optical system which emits a charged particle beam, the system including an electrostatic lens, and a grid electrode opposed to the electrostatic lens along an optical axis of the electrostatic lens, and configured to form an electrostatic field in cooperation with the electrostatic lens, wherein the grid electrode is configured such that an electrode surface, opposed to the electrostatic lens, of the grid electrode has a distance, from the electrostatic lens in a direction of the optical axis, which varies with a position in the electrode surface.
US08716666B1 Method of detecting contaminant materials in food products
Disclosed herein is a method of detecting a contaminant material in a food sample. The method includes irradiating a food sample with a beam of electromagnetic radiation, the beam having a plurality of frequencies in the range of about 100 GHz to about 2 THz; detecting radiation transmitted and/or reflected from the food sample; and, analyzing the detected radiation to determine the presence of contaminant material. The contaminant material may be melamine, cyanuric acid, ammeline, or ammelide.
US08716665B2 Compact optical proximity sensor with ball grid array and windowed substrate
Various embodiments of a compact optical proximity sensor with a ball grid array and windowed or apertured substrate are disclosed. In one embodiment, the optical proximity sensor comprises a printed circuit board (“PCB”) substrate comprising an aperture and a lower surface having electrical contacts disposed thereon, an infrared light emitter and an infrared light detector mounted on an upper surface of the substrate, an integrated circuit located at least partially within the aperture, a molding compound being disposed between portions of the integrated circuit and substrate, an ambient light detector mounted on an upper surface of the integrated circuit, first and second molded infrared light pass components disposed over and covering the infrared light emitter and the infrared light detector, respectively, and a molded infrared light cut component disposed between and over portions of the first and second infrared light pass components.
US08716663B2 Device and method for particle therapy monitoring and verification
The present invention relates to a device and method for monitoring and verification of the quality of a radiation treatment beam in conformal radiation therapy, and in particular for IMPT (Intensity Modulated Particle Therapy) applications. The device comprises a 2D electronic detector measuring 2D responses to the delivered treatment beam. These 2D responses are compared with predicted 2D responses and differences in responses are signalled. Based on the measured 2D responses the effectively delivered 3D dose distribution in the target can be reconstructed.
US08716661B1 Method for measuring size of specimen
A method for measuring a size of a specimen is provided. A first projected width of the specimen is obtained at a first angle with the help of an energy source then a second projected width of the specimen is obtained at a second angle with the help of the energy source. The first projected width, the first angle, the second projected width and the second angle are co-related to indirectly obtain a size of the specimen which has not been measured. The un-measured size is not directly involved with the first projected width and the second projected width.
US08716660B2 Ion guide with orthogonal sampling
A mass spectrometer is disclosed comprising a RF ion guide wherein in a mode of operation a continuous, quasi-continuous or pulsed beam of ions is orthogonally sampled from the ion guide and wherein the continuous, quasi-continuous or pulsed beam of ions is not axially trapped or otherwise axially confined within the RF ion guide. The ion guide is maintained, in use, at a pressure selected from the group consisting of: (i) 0.0001-0.001 mbar; (ii) 0.001-0.01 mbar; (iii) 0.01-0.1 mbar; (iv) 0.1-1 mbar; (v) 1-10 mbar; (vi) 10-100 mbar; and (vii) >100 mbar.
US08716659B2 Quadrupole mass spectrometer including voltage variable DC and amplitude variable AC for selected ion monitoring / scan alternate measurement
Disclosed is a quadrupole mass spectrometer, which is capable of, during an SIM measurement, maximally reducing a settling time-period necessary for an operation of changing an input voltage to a quadrupole mass filter in a staircase pattern, and preventing unwanted ions from excessively entering a detector during a course of changing between a plurality of mass values. Under a condition that a response speed of a DC voltage U to be applied to quadrupole electrodes is less than that of an amplitude of a high-frequency voltage V, a control section 10 is operable to rearrange the mass values in descending order of mass value, and an optimal settling-time calculation sub-section 101 is operable to determine a settling time-period for each of the mass values, based on a mass-value difference and a post-change mass value.
US08716654B2 Electrostatic trap
An electrostatic trap such as an orbitrap is disclosed, with an electrode structure. An electrostatic trapping field of the form U′ (r, Φ, z) is generated to trap ions within the trap so that they undergo isochronous oscillations. The trapping field U′(r, Φ, z) is the result of a perturbation W to an ideal field U(r, Φ, z) which, for example, is hypologarithmic in the case of an orbitrap. The perturbation W may be introduced in various ways, such as by distorting the geometry of the trap so that it no longer follows an equipotential of the ideal field U(r, Φ, z), or by adding a distortion field (either electric or magnetic). The magnitude of the perturbation is such that at least some of the trapped ions have an absolute phase spread of more than zero but less than 2 π radians over an ion detection period Tm.
US08716649B2 Optical gesture sensor using a single illumination source
A gesture sensing device includes a single light source and a multiple segmented single photo sensor, or an array of photo sensors, collectively referred to herein as segmented photo sensors. A light modifying structure relays reflected light from the light source onto different segments of the segmented photo sensors. The light modifying structure can be an optical lens structure or a mechanical structure. The different segments of the photo sensor sense reflected light and output corresponding sensed voltage signals. A control circuit receives and processes the sensed voltage signals to determine target motion relative to the segmented photo sensor.
US08716644B2 Glare reduction apparatus
The invention provides a glare reduction apparatus disposed in an object illuminated by a light source. The glare reduction device includes an electro-optical device covering a surface of the object. A light sensing device is disposed on a first fixed point of the object. A controller is electrically coupled to the electro-optical device and the light sensing device, wherein the controller calculates a corresponding light sensing position of the electro-optical device according to a light sensing position of the light sensing device which directly receives light from the light source, to reduce the light transmittivity of the corresponding light sensing position of the electro-optical device to generate a light shielding region. The light shielding region attenuates the light from the light source to a second fixed point of the object.
US08716643B2 Single photon counting image sensor and method
A single photon counting image sensor and method is provided. In one aspect, the method of an image sensor includes counting through a counter circuit a number of photons detected through a photodiode when a light is incident on the photodiode. The method also includes storing in a memory circuit a time a count of the number of photons take to match a reference count of the number of photons. In another aspect, an image sensor device includes a pixel circuit. The image sensor device also includes a photodiode circuit of the pixel circuit to detect photons when a light is incident on the photodiode circuit. The image sensor device further includes a counter circuit of the pixel circuit coupled to the photodiode circuit to count a number of photons detected when a light is incident on the avalanche photo diode.
US08716642B2 Method and device for automatic compensation of solar sunlight tracing panel inclination
The present invention provides a method and a device for automatic inclination compensation of solar sunlight tracing panel. The device includes a plurality of solar panels adjacent to each other and capable of swinging towards sun. Two or more light sensors are separately installed on the light receiving end surface to be illuminated by sunlight and to generate electric potential signals. When comparing the electric potential signals and there is potential difference, the solar panels are driven to synchronically swing until the electric potential of the electric potential signal become the same. Thus the solar plane inclination is compensated and the whole light receiving end is illuminated by sun.
US08716641B2 Scanning imaging device for imaging target on a substrate
A scanning imaging device has a spot light projecting section 101 that irradiates a first spot light for excitation and two second spot lights for focus detection onto a flow channel of a substrate 4 and an imaging section 102 for picking up an image of light emitted from a target of detection in the flow channel as it is excited by the first spot light. One of the second spot lights is reflected at the top surface of the flow channel and the other of the second spot lights is reflected at the bottom surface of the flow channel and a focus position adjustment mechanism for adjusting the focus position of each of the first and second spot lights in the depth direction of the flow channel such that the quantity of deviation of the focus positions of the first and second spot lights in the depth direction of the flow channel as determined by comparing the intensities of the one and the other of the second reflected lights reflected at the flow channel.
US08716640B2 Piloting device of a missile or of a projectile
The invention concerns the field of devices for improving the piloting of projectiles More specifically, the object of the invention is a piloting device for a missile or a projectile, for example, of small caliber, especially on the order of 40 mm, which has a lateral main surface with a nose at the level of one of its extremities, whereby said device includes at least one cavity consisting of a combustion chamber and filled, at least partially, by an explosive powder, and means of initiation of this explosive powder, and thereby the explosive powder includes nanothermites or gas-generating nanothermites.
US08716638B2 Microwavable container with sleeve
A food package kit including a plurality of trays having a bottom, a sidewall extending upwardly from the bottom and terminating at a top end, and a flange extending from the sidewall opposite the bottom, the flange includes a rim section configured to receive a sealing film, and a recessed section extending from the rim section, wherein each of the opposed longitudinal edges intersect with a lateral edge at a corner, wherein the kit also includes a sleeve adapted to contain the trays completely therein, the sleeve including a sleeve top, a first depending sleeve side, and a second depending sleeve side and a sleeve bottom, wherein the tray is completely disposed within the sleeve by frictional force between the tray and the sleeve.
US08716636B2 Arrangement and method for powering inductors for induction hardening
An arrangement for induction hardening a part including a pair of separate inductors electrically isolated from each other and configured to substantially surround a part when brought into close juxtaposition with each other. The inductor sections are powered by respective secondary inductor loops brought into close juxtaposition with a primary inductor loop connected to an ac power source which induces an ac current in each inductor section.
US08716635B2 Honeycomb structure
A honeycomb structure includes: a honeycomb structural portion having porous partition walls functioning as fluid passages and separating and forming a plurality of cells extending from one end face to the other end face. The partition walls and the outer peripheral wall contain silicon carbide particles as a framework and silicon as a binder for binding the silicon carbide particles. The honeycomb structure has a partition walls thickness of 50 to 200 μm, a cell density of 40 to 150 cells/cm2, and an average particle diameter of the silicon carbide as a framework of 3 to 40 μm. The honeycomb structural portion has a volume resistivity of 1 to 40 Ωcm at 400° C., and the volume resistivity of the electrode portion at 400° C. is not more than 40% of the volume resistivity of the honeycomb structural portion at 400° C.
US08716632B1 Ceramic scent bowl and method for heating a scent bowl
A scent bowl may include a base having an external concave base surface and at least one sidewall extending from the base. A majority of the base and the at least one sidewall may be formed of ceramic material. A system for scenting the air in a room with scent from a scent bowl may include a scent bowl warmer configured to generate heat at a first temperature and a detachable and separate scent bowl including a base having an external concave base surface and at least one sidewall extending from the base and a scent emitter therein, the scent emitter having a fragrance and a second temperature at which the fragrance evaporates. The first temperature is high enough to evaporate at least a portion of the fragrance from the scent emitter in the bowl in less than three hours.
US08716627B2 Welding systems and methods
A welding system is provided for welding a first work piece to a second work piece at a joint having a weld face and a root face. The welding system includes a weld face sensor configured to determine first joint characteristics at the weld face; a root face sensor configured to determine second joint characteristics at the root face; a controller coupled to the weld face sensor and the root face sensor and configured to generate positioning signals based on the first joint characteristics and the second joint characteristics; and a welding gun coupled to the controller and positioned proximate to the weld face, the welding gun configured to generate a welding beam for welding the joint based on the positioning signals from the controller.
US08716626B2 Shielded metal arc welding machine
A shielded metal arc welding machine having a characteristic with a constant current output characteristic and a drooping output characteristic properly combined is provided. A shielded metal arc welding machine having a constant current output characteristic, characterized by having a desired drooping output characteristic, which has an optional drooping degree with a point at which a characteristic line of said constant current output characteristic intersects a welding load characteristic line L as a base point, and replaces said constant current output characteristic.
US08716620B2 Laser head with axial crash protection
An upper housing assembly includes a pivot arm having an upper cam surface adjacent a distal end. A cam follower is coupled to a laser head to move up and down with a laser head. The cam follower exerts a downward force on the upper cam surface during normal operation. Thus, as the pivot arm rotates back and forth, the laser head moves up and down. A assist gas hose can be coupled between the upper housing and the laser head which has a spiral configuration permitting relative axial movement between the upper housing and the laser head. Upon an upward axial force being exerted on the laser head, the cam follower moves upwardly away from the upper cam surface.
US08716618B2 Angle grinder
An angle grinder is provided including a trigger assembly for selectively actuating the angle grinder. A particle separation assembly is provided for the removal of any dust, particle, or artifacts that may have entered into the housing of the angle grinder. A brush biasing system is also provided to ensure proper and efficient operation of the motor of the angle grinder. An overload monitoring system is included to monitor the loading on the motor. A clutch mechanism is also included to prevent overloading on the motor of the angle grinder. A gear wheel lock mechanism is also provided to prevent the wheel spindle from rotating during installation or removal of a grinding wheel on the wheel spindle. An anti-locking flange system is also included to prevent the over-tightening of the flanges and the grinder wheel during the operation of the angle grinder. A gear case labyrinth feature is also provided.
US08716617B2 Activation switch for a power tool
A power tool includes a linear activation switch incorporating features to prevent accidental activation. More particularly, the switch includes a switch cap that must be first rotated or pivoted before it can be linearly translated to activate the switch. The power tool includes a housing defining a guide track having a first section and an second section, offset from each other by a third section. The switch includes a switch cap having guide ribs, a first slidably disposed within the first section and a second rib one initially situated within the third section. The switch cap is pivotable about the first guide rib so that the second guide rib moves within the third section into alignment with the second section of the guide track. The switch cap can then be moved linearly with the second guide rib sliding within the second section, with this movement activating the switch.
US08716616B2 Main switch for electrical systems of vehicles
A main switch for electrical systems of vehicles, comprising an outer casing projecting from which is a plurality of electrical contacts that are to be connected to cables of the electrical system, wherein the casing has a base that is to rest on a supporting plate of the vehicle, said base being fixed by means of screws to the supporting plate, wherein the base is provided with two pairs of fixing elements having respective holes that are to be engaged by said screws, said fixing elements being insertable in the respective seats of the base in two different positions to which there correspond different distances between the centers of the fixing elements of each pair.
US08716615B2 Conduction breaking device
A conduction breaking device includes a movable member accommodated in an accommodation chamber of a case. A cutter portion projects from an advancing side of the movable member in the moving direction. A gas generator is arranged on the trailing side of the movable member in the moving direction. A conduction member extends to connect a pair of external connection portions and includes a pair of base portions and a breakable portion. The base portions are located in the side wall of the case and extend along the moving direction of the movable member. The breakable portion is shaped to connect the base portions to each other and to block the advancing side of the movable member in the moving direction. Step portions are formed in the breakable portion. Engaging portions that are engageable with the step portions are formed in the case.
US08716614B2 Touch pad and a method of operating the touch pad
A touch pad is controlled to detect a location of one or more objects (16) on a touch surface (15) of a transmissive element (12). The touch pad includes at least two scanning arrangements (24-26, 28, 29) which are configured as optical scanning transceivers. Each scanning arrangement is adapted to provide a beam of radiation along a pertaining direction (18) in the transmissive element (12), such that the beam propagates inside the transmissive element (12) by total internal reflection. Each scanning arrangement is also adapted to receive radiation from the transmissive element (12) and from the pertaining direction (18), and output corresponding signal. Each scanning arrangement is further adapted to scan the pertaining direction substantially along the touch surface (15). A processing element is arranged to determine, on the basis of the signals from the scanning arrangements, one or more positions on the touch surface (15) where scattering/absorption of radiation occurs as a result of the touching object or objects (16).
US08716612B2 Housing of a weighing scale with a a circumferential edqe that rims the circumferential separating wall, so that when the housing is in a closed state, the circumferential edge co-acts with an inside surface of the second housing part to define a second enclosed space serving to house the electronic components
A housing (1) encloses electronic components (2) that control operation of a weighing scale. The housing has a first housing part (10) and a second housing part (30). The respective housing parts are designed to form a first enclosed space (6) for housing the electronic components between the respective housing parts. A fastening module (60) is arranged between the respective housing parts. The fastening module has a first side (61) and an opposing second side (62). The first side includes first and second circumferential seating ledges (63, 64) that receive, respectively, the first and second housing parts.
US08716611B2 Weighing scale housing with carrier unit for electronics mounted on guiding tracts for removal from the housing, wherein the carrier also serves as a closure plate for the bottom of the pedestal opening
A weighing scale (10) has a display/operating unit (20), a scale platform (30), an electronic system (60) for the control of the scale (10), and a pedestal (40) that connects the display/operating unit to the scale platform. The pedestal contains a pedestal chamber (41). The pedestal also has a pedestal opening (42). A carrier element (70) is arranged in or at the pedestal chamber. At least parts of the electronic system are arranged on the carrier element, and the parts of the electronic system which are arranged on the carrier element can be at least partially taken out of the pedestal opening for servicing.
US08716610B2 Elastic handle integrated luggage scale
A handle integrated scale configured to fixedly attach to a liftable element that allows a user to ascertain the weight of said liftable element based on the amount of force exerted onto the handle integrated scale from the liftable element as it is lifted.
US08716599B2 Pipeline continuity connector
Provided herein is a connecting strap or spanning strap that is adapted for use in interconnecting adjacent insulated and/or electrically isolated pipeline sections to provide electrical continuity. Various aspects of the spanning strap are based on the realization that different attachment mechanisms may benefit from differing geometries of the spanning strap. Specifically, it's been determined that the geometry of an attachment aperture extending through the connection strap for use in welding or soldering strapped an underlying surface may be advantageously designed.
US08716595B2 Boron nitride anti-reflection coatings and methods
High performance photovoltaic devices are provided. Certain embodiments relate to the use of Boron-Nitride (BN) thin films as anti-reflection coating (ARC) material on Si and GaAs solar cells. A low and wide reflectance window covering a large energy range of the solar spectrum is available. For a large part of the useful solar spectrum, the index of refraction of the grown BN thin films remains constant at about 2.8. In another embodiment, a BN ARC is applied directly on ordinary window glass providing the device's mechanical strength.
US08716588B2 Key press switch for electronic piano
A key press switch includes a main body portion configured to contact a pseudo hammer of the electronic piano and a contact portion provided in a part of the main body portion to contact the pseudo hammer. The contact portion includes a first contact portion and a second contact portion located closer to the fulcrum than the first contact portion. The contact portion is configured such that a contact position with the pseudo hammer is shifted from the first contact portion to the second contact portion in accordance with the key press amount of the electronic piano from the amount at which, in a standard acoustic piano, the damper load starts to be applied until the amount at which, in a standard acoustic piano, the damper load has been fully applied.
US08716587B2 Musical instruments
Musical instruments are described including a first portion designed to be operated by one hand of a player and a second portion designed to be operated by the other hand. The two portions include means within each for sensing hand and/or finger activity, position or movement, and one of the portions is adapted to produce an output signal corresponding to the music being played by the user. The two portions may be physically connected together or they may be separate, each including its own power supply to enable it to operate, and for the two portions to communicate with one another. The invention is of particular value in the construction of practice instruments which do not need to include a sound box, and can thus be very compact, especially if the two parts, such as a fingerboard (20) and a body (82) with strings (83) mounted on it are connected by a telescopic neck (60A).
US08716585B2 Customizable electronic musical instrument and user interface
A customizable electronic musical instrument comprising a mounting frame for securing a plurality of user-installable electronic musical modules of various types including a type for generating at least one real-time control signal responsive to user operation, a type for generating audio signals, responsive to a real-time control signal, and a for processing audio signals responsive to at least one of a real-time control signal. The instrument can transmit electrical signals to an external system and can include internal sound amplification. The instrument can include one or more of a keyboard, touchpad, strumpad, impact sensor, slider control, expression wheel, joystick, ribbon controller, button, switch, pressure sensor, multiple-position selector, knob potentiometer, and music synthesizer elements. Signals may be routed among modules by a switch or bus.
US08716582B2 Jingle shaker
A percussive shaker instrument with improved control in producing rhythmic sound and capable of producing different percussive sounds in a single shaker is disclosed. The shaker comprises one or more channels filled with a striker material. The channel isolates the striker material from the striker material in other channels and from any other part of the shaker. The striker material is freely movable within the channel such that it may collide with a striking surface when the shaker is moved. Alternatively, the shaker may comprise one or more pairs of jingles suspended inside the shaker body. The jingles are freely movable within the body such that they are capable of striking each other when the shaker is moved.
US08716578B2 Plants and seeds of hybrid corn variety CH237946
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH237946. The invention thus relates to the plants, seeds and tissue cultures of the variety CH237946, and to methods for producing a corn plant produced by crossing a corn plant of variety CH237946 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH237946.
US08716575B1 Maize inbred PH1CJ4
A novel maize variety designated PH1CJ4 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1CJ4 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1CJ4 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1CJ4 or a locus conversion of PH1CJ4 with another maize variety.
US08716574B1 Maize inbred PH1M7A
A novel maize variety designated PH1M7A and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1M7A with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1M7A through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1M7A or a locus conversion of PH1M7A with another maize variety.
US08716570B2 Soybean cultivar S110127
A soybean cultivar designated S110127 is disclosed. The invention relates to the seeds of soybean cultivar S110127, to the plants of soybean cultivar S110127, to the plant parts of soybean cultivar S110127, and to methods for producing progeny of soybean cultivar S110127. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S110127. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S110127, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S110127 with another soybean cultivar.
US08716566B2 Soybean cultivar SJ0912741
The present invention is in the field of soybean variety SJ0912741 breeding and development. The present invention particularly relates to the soybean variety SJ0912741 and its progeny, and methods of making SJ0912741.
US08716562B1 Soybean cultivar 06RM936409
The present invention is in the field of soybean cultivar 06RM936409 breeding and development. The present invention particularly relates to the soybean cultivar 06RM936409 and its progeny, and methods of making 06RM936409.
US08716559B2 Compositions and methods for altering alpha- and beta-tocotrienol content
Preparation and use of isolated nucleic acids useful in altering the oil phenotype in plants. Isolated nucleic acids and their encoded polypeptides that alter alpha- and beta-tocotrienol content in seeds and oil obtained from the seeds. Expression cassettes, host cells and transformed plants containing the foregoing nucleic acids.
US08716557B2 Compositions and methods for inhibition of fucosyltransferase and xylosyltransferase expression in plants
Methods for altering the N-glycosylation pattern of proteins in higher plants are provided. The methods comprise introducing into the plant a recombinant RNAi construct that provides for the inhibition of expression of α1,3-fucosyltransferase (FucT) and β1,2-xylosyltransferase (XylT) in a plant. Use of these RNAi constructs to inhibit or suppress expression of both of these enzymes, and isoforms thereof, advantageously provides for the production of endogenous and heterologous proteins having a “humanized” N-glycosylation pattern without impacting plant growth and development. Stably transformed higher plants having this protein N-glycosylation pattern are provided. Glycoprotein compositions, including monoclonal antibody compositions, having substantially homogeneous glycosylation profiles, and which are substantially homogeneous for the G0 glycoform, are also provided.
US08716555B2 Cottonseed oil and uses
The present specification relates to the production of cotton plants and seeds and oil prepared therefrom having elevated levels of oleic and reduced levels of palmitic and linoleic acids. Furthermore, cottonseeds having low levels of cyclopropane and/or cyclopropene fatty acids and/or reduced levels of gossypol are described herein. The specification also describe FatB and CPA-FAS nucleotide and amino acid sequences derived from cotton facilitating, inter alia the direct modification of plant oil content and/or composition.
US08716552B1 Maize hybrid X95C381
A novel maize variety designated X95C381 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X95C381 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X95C381 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X95C381, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X95C381. This invention further relates to methods for producing maize varieties derived from maize variety X95C381.
US08716551B2 Production of hybrid Lactuca sativa seeds
The present invention concerns hybrid Lactuca sativa seeds which have a male sterile genotype and which are heterozygous for at least one distinct gene which provides plants derived from said seeds with a distinct phenotype. The invention also concerns a method for producing hybrid Lactuca sativa seeds, comprising a step for culture, in an enclosed medium, of phenotypically male sterile plants and phenotypically male fertile plants, a step for pollinization by diptera introduced into the closed medium upon flowering of the plants, and a step for harvesting the seeds produced by the male sterile plants.
US08716550B2 Method for the selection of plants with specific mutations
The present invention relates to a method for the provision of mutagenised populations by the introduction of mutations by chemically and or physically mutagens in a selected region of the genome of a plant and the subsequent selection of inheritable mutations by analysis of at least one section of a mutagenised primary M1 plant for the presence of a mutation in the region of interest using high throughput sequencing.
US08716549B2 Absorbent article with bonded web material
An absorbent article to be worn the lower torso is provided. The absorbent article comprises a chassis comprising a topsheet, a backsheet, an absorbent core, and a pair of longitudinal barrier cuffs attached to the chassis. Each of the longitudinal barrier cuffs comprises a web of material. The web of material comprises a first nonwoven component layer, and a second nonwoven component layer. Each of the longitudinal barrier cuffs comprises a longitudinal zone of attachment where each of the longitudinal barrier cuff attaches to the chassis, a longitudinal free edge, and a plurality of mechanical bonds disposed between the longitudinal zone of attachment and the free edge. The plurality of mechanical bonds attach one of a first portion of the web of material to a second portion of the web of material, and the web of material to a portion of the absorbent article.
US08716547B2 Stretch laminates
A stretch laminate having a first substrate is adhesively attached to an elastic film. The adhesive is applied in a continuous manner to the substrate in a first tack down region which is disposed proximate to an end of the stretch laminate. The adhesive is applied as a plurality of adhesive stripes in an activation region which is interior of the first tack down region. The adhesive stripes have a width and a distance between adjacent adhesive stripes. The ratio of stripe width to distance between the adhesive stripes is in the range of less than about 1 or greater than about 0.33.
US08716546B2 Steam plasma arc hydrolysis of ozone depleting substances
A two step process for the destruction of a precursor material using a steam plasma in a three zone reactor wherein the precursor material is hydrolyzed as a first step in the high temperature zone of the reactor, followed by a second step of medium temperature oxidation of the reactant stream in the combustion zone of the reactor where combustion oxygen or air is injected and immediate quenching of the resulting gas stream to avoid the formation of unwanted by-products. A related apparatus includes a non transferred direct current steam plasma torch, an externally cooled three zone steam plasma reactor means for introducing the precursor material into the plasma plume of the plasma torch, means for introducing the combustion air or oxygen into the combustion zone, means for exiting the reactant mixture from the reactor and means for quenching the reactant mixture located at the exit end of the reactor.
US08716544B2 Process for isomerizing a feed stream including one or more C4-C6 hydrocarbons
One exemplary embodiment can be a process for isomerizing a feed stream including one or more C4-C6 hydrocarbons. Generally, the process includes contacting the feed stream in an isomerization reaction zone with an isomerization catalyst at isomerization conditions to produce an isomerization zone effluent; passing at least a portion of the isomerization zone effluent to a stabilizer zone and recovering a stabilizer overhead stream, a bottom stream, and a side-stream; passing at least a portion of the side-stream to a stripper zone; and sending a stripper bottom stream to a C5 splitter zone and passing a stream from the C5 splitter zone to the isomerization reaction zone. Generally, the stabilizer overhead stream can include one or more C5− hydrocarbons, a bottom stream can include at least about 85%, by weight, one or more C6+ hydrocarbons, and a side-stream can include at least about 85%, by weight, one or more C5+ hydrocarbons. Also, the stripper bottom stream can include at least about 90%, by weight, one or more C5+ hydrocarbons.
US08716536B2 Process for the preparation of directly compressible δ-mannitol
The present invention relates to a process for the preparation of directly compressible mannitol having a content of the δ modification of greater than 90%.
US08716534B2 Precursors to fluoroalkanol-containing olefin monomers, and associated methods of synthesis and use
The invention provides alkene fluoroalkanol and fluorinated polyol precursors to fluoroalkanol-substituted α,β-unsaturated esters. The fluoroalkanol-substituted α,β-unsaturated esters are olefins that can be readily polymerized to provide fluoroalkanol-substituted polymers useful in lithographic photoresist compositions. Also provided are methods for synthesizing the alkene fluoroalkanol and fluorinated polyol precursors.
US08716533B2 Methods of saponifying xanthophyll esters and isolating xanthophylls
This invention relates to a practical and effective process for converting esterified xanthophylls, including zeaxanthin, to non-esterified xanthophylls through saponification. In addition, the invention provides a process for obtaining esterified zeaxanthin in high yields and purities, isolating the xanthophylls from interfering substances such as waxes, oils, and fats. A product of this process is a zeaxanthin rich substrate that is suitable for use in foods, nutritional supplements, cosmetics, pharmaceuticals and related products.
US08716532B2 One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation
The present invention provides a method for the preparation of some novel multiconjugated 2- or 4-hydroxy substituted stilbenes. The method provides one pot multicomponent approach wherein 3-4 step reaction sequences viz. condensation, decarboxylation and Heck coupling occur simultaneously which results in an enhanced yield of desired products and reduced reaction times.
US08716530B2 Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof
The present invention discloses methods of use of facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, including, but not limited to, pharmaceutical uses of the polymers and oligomers as antimicrobial agents and as antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, compositions of the novel polymers and oligomers, including pharmaceutical compositions, and methods of designing and synthesizing the facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers.
US08716529B2 Amine derivative compounds for treating ophthalmic diseases and disorders
Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
US08716528B2 Aryloxy amine compounds and their use as sodium channel modulators
The present invention relates generally to the field of therapeutic treatment and compounds having utility therefor, in particular the therapy or management of conditions associated with excessive, unwanted or undesirable sodium ion passage through cellular membranes via voltage-gated sodium channels. In one embodiment the invention is concerned with the treatment of neuropathic pain. The invention contemplates to aryloxy-substituted amines, as sodium channel blockers or modulators. In further embodiments, the invention also relates to compounds which may advantageously have dual sodium channel blocker/modulating and antioxidative (free-radical scavenging) effects. Methods for their manufacture and compositions containing the compounds are also contemplated.
US08716523B2 Catalyst for use in production of methacrylic acid and method for manufacturing the same
A method for manufacturing a catalyst of which active components are partly neutralized salt of heteropoly acid comprising molybdenum, phosphorus, vanadium, cesium, antimony, and ammonia as essential components, wherein the method is characterized in mixing an antimony compound with a complex oxide of the essential active components in the catalyst containing active components other than antimony, wherein the antimony compound may be added during slurry preparation.
US08716520B2 Method of resolution of (RS)- 1,1′-BI-2-naphthol for obtaining enantiomeric pure I.E. (S)-(−)-1,1′-BI-2-naphthol and/or (R)-(+)-1,1′-BI-2-naphthol via co-crystal formation with optically active derivatives of γ-amino acids
Novel method for synthesis of optically pure (S)-(−)-1,1′-bi-2-naphthol and/or (R)-(+)-1,1′-bi-2-naphthol via resolution of racemic (RS)-1,1′-bi-2-naphthol through formation of co-crystal with optically active derivatives of γ-amino acids.
US08716519B2 Cross-linkable monomers and polymers and the use thereof
The invention relates to novel cross-linkable monomers that may be polymerized with ethylenically unsaturated comonomers to form cross-linkable copolymers. Said copolymers may particularly be used in the form of aqueous dispersions as formaldehyde-free adhesives or as coatings with good water resistance. The cross-linkable monomer is a compound in acid or salt form comprising an anion of the formula (I) and one or more cations for producing electrical neutrality, where R1 and R2 represent, independently of one another, hydrogen alkyl, cycloalkyl, aryl, aralkyl, —COOR5, —COO− cat+ or —CON(R6R7), R6 and R7 represent, independently of one another, hydrogen, alkyl, or aryl, cat+ represents a monovalent cation, and one of the groups R1 or R2 may also represent a group —X—R4—CR5(OH)SO3−), wherein X, R4, and R5 assume one of the meanings listed below, R3 represents hydrogen, alkyl, or aryl, X is selected from the group of direct C—C bond, —O—, —CH2—O—, —CH2—NR8—, —COO— or —CONR8—, R8 represents hydrogen, alkyl, or aryl, R4 represents alkylene, polyoxyalkylene, cycloalkylene, or arylene, and R5 represents hydrogen, alkyl, cycloalkyl, or aryl.
US08716518B2 Photoacid generating monomer and precursor thereof
A monomer compound has the formula (I): where each R1, R2, and R3 is independently H, F, C1-10 alkyl, fluoro-substituted C1-10 alkyl, C1-10 cycloalkyl, or fluoro-substituted C1-10 cycloalkyl, provided that at least one of R1, R2, or R3 is F; n is an integer of from 1 to 10, A is a halogenated or non-halogenated C2-30 olefin-containing polymerizable group, and G+ is an organic or inorganic cation. The monomer is the reaction product of a sultone precursor and the oxyanion of a hydroxy-containing halogenated or non-halogenated C2-30 olefin-containing compound. A polymer includes the monomer of formula (I).
US08716515B2 Process for the preparation of polyether ester polyols
The present invention relates to a process for the preparation of polyether ester polyols starting from fatty acid esters and starter compounds having Zerewitinoff-active hydrogen atoms, and to their use in the production of solid or foamed polyurethane materials.
US08716513B2 Process for production of bis-quaternary ammonium salt, and novel intermediate
Object To provide a method for producing a bis-quaternary ammonium salt efficiently and a novel synthetic intermediate thereof.Solution The present invention relates to a method for producing a bis-quaternary ammonium salt represented by a general formula [3] which comprises reacting a disulfonic acid ester represented by a general formula [1] (in the formula, definitions of two R1's and T are as described in claim 1) with a tertiary amine represented by a general formula [2] (in the formula, definitions of R3 to R5 are as described in claim 1), and a disulfonic acid ester represented by a general formula [1′] (in the formula, two R16's represent independently a halogen atom or a C1-C3 fluoroalkyl group, and two m's represent independently an integer of 1 to 5).
US08716512B2 Preparation and purification of subunit vaccine for Neisseria meningitidis (NM) group B isolates
A method for preparing and purifying recombinant lipoprotein Ag473 of Neisseria meningitidis (NM) group B isolates. The method can be used in large-scale production of vaccines for Neisseria meningitidis (NM) group B.
US08716510B2 Blue light emitter with singlet harvesting effect for use in OLEDs and other organic-electronic devices
The invention relates to the use of a platinum-dicyano-bisisocyanide complex cluster, having a small ΔE distance, in particular between 500 cm−1 and 3000 cm−1, between the lowest triplet state and the overlying singlet state that is populated by means of thermal repopulation from the triplet, in an organic-electronic device for emission of blue light and for absorption in the ultraviolet and blue spectral range. The invention also relates to the use of the singlet harvesting method. Furthermore, the invention relates to the use of the high degrees of absorption of such platinum-dicyano-bisisocyanide complex clusters.
US08716508B2 Method for preparing a metal catalyst
The present disclosure relates to a method for preparing a metal catalyst comprising at least one ligand that is coordinated to the metal through at least one phosphorous (P) atom and at least one nitrogen (N) atom, the method comprising reacting a metal pre-cursor complex with an acid addition salt of an aminophosphine, diaminophosphine, aminodiphosphine or diaminodiphosphine, in the presence of a base.
US08716505B2 Refining of edible oil
The present invention discloses a commercial process for the production of refined palm oil rich in natural carotene. The process for the production of natural carotene rich refined oil comprises the steps of: (i) fractionating crude palm oil to form a liquid fraction and a solid portion; (ii) separating the liquid fraction from the solid portion; (iii) degumming the liquid fraction; (iv) neutralizing the degummed liquid fraction to substantially remove free tatty acids and impurities; (v) washing off the soap resulting from the neutralization step; and (vi) deodorizing the neutralized the product of step (v) to remove remaining free fatty acids and other impurities contained therein, thus forming a refined palm oil that contains less than 0.1% free fatty acid, has a carotene content retained of about 75%, an iodine value of less than 60 and a peroxide value of zero.
US08716502B2 Process for preparing divinylarene oxides
A process for preparing a divinylarene oxide including (a) reacting (i) at least one divinylarene; (ii) at least one peroxycarboximidic acid; (iii) at least one solvent; and (iv) at least one basic compound, under reaction conditions to form a reaction effluent containing a divinylarene oxide product; and then (b) evaporating the reaction effluent of step (a) to form a concentrate containing the divinylarene oxide product; and wherein the concentrate separates into two liquid phases.
US08716501B2 Method for producing oxygen-containing compound
[Problem] There is provided a method for producing an oxygen-containing compound safely and with improved reaction efficiency, in which an undesired peroxide is unlikely to be produced, and efficient heat exchange of the ozonization can be achieved.[Mean for solving the Problem] The method comprises an ozonization reaction step of continuously supplying, together with an organic compound, ozone having an oxygen content of less than 10% in a dissolved state in high-pressure carbon dioxide to an ozonization reaction section having a thin tubular shape, and reacting the ozone and the organic compound under conditions that suppress generation of oxygen due to thermal decomposition of the ozone, thereby continuously producing an ozonide; and a decomposition reaction step of continuously supplying the ozonide produced in the ozonization reaction step to a decomposition reaction section having a thin tubular shape, thereby continuously producing an oxygen-containing compound, the decomposition reaction step being provided in a manner continuous with the ozonization reaction step.
US08716499B2 Benzenoid compounds of antrodia cinnamomea, preparation and analysis method thereof
Disclosed are a method for preparing an n-hexane extract of the fruiting body of Antrodia cinnamomea (AC), wherein the fruiting body of AC is sequentially extracted with the ethanol solution and the n-hexane solution to obtain the n-hexane extract containing at least one benzenoid compound. The amounts of 4,7-dimethoxy-5-(3-methylbut-3-en-1-ynyl)-6-methyl-1,3-benzodioxole, 4,7-dimethoxy-5-methyl-1,3-benzodioxole, antrocamphine A and the combination thereof in the at least one benzenoid compound are determined using chromatography, NMR and HPLC. In addition, the present invention is applicable on detecting the amounts of benzenoid compounds in the AC healthcare food/drug or the fruiting body of AC, and thus owns the industrial values.
US08716496B2 Sulfonated coumarins, their synthesis, fluorogenic substrates resulting from grafting of these coumarins on sugars, method for obtaining these substrates, and their applications
Substituted sulfonated coumarins are expressed in the general formula (I), where: R1 is H, OH, or a substituted or unsubstituted, straight or branched C1-C6 alkyl radical, or —COR4, or —COOR4, or —CONHR4, R2 is H or a halogen, in particular fluorine, or a substituted or unsubstituted, straight or branched C1-C6 alkyl radical, or —COR4, or —COOR4, or —CONHR4, R1 and R2 being capable of together forming a ring, such as a substituted or unsubstituted aryl or furane, R3 is H or a halogen, in particular fluorine, or a substituted or unsubstituted, straight or branched C1-C6 alkyl radical, or —COR4, or —COOR4, or —CONHR4, where R4 is H, or a substituted or unsubstituted, straight or branched C1-C6 alkyl radical, or a substituted or unsubstituted aryl, and M is Na or K.
US08716495B2 Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid
The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.
US08716489B2 Oxadiazole derivative, light-emitting element material, light-emitting element, light-emitting device, and electronic device
An object is to provide a novel material having a bipolar property. Another object is to provide an oxadiazole derivative having a wide band gap. Another object is to reduce power consumption of a light-emitting element, a light-emitting device, and an electronic device. The present invention provides an oxadiazole derivative represented by General Formula (1). In the formula, Ar1 represents a substituted or unsubstituted aryl group having 6 to 10 carbon atoms in a ring, A represents a substituted or unsubstituted phenylene group, R11 to R15 and R21 to R25 are independently any of hydrogen, an alkyl group having 1 to 4 carbon atoms, an aryl group having 6 to 10 carbon atoms in a ring, and a substituted or unsubstituted 9H-carbazol-9-yl group.
US08716485B2 Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines
The invention describes a novel process for synthesizing pyrazoles by means of oxidative conversion of enamines with suitable N-containing carboxylic acid derivatives.
US08716484B1 Hole transporting materials with twisted aryl groups
Novel compounds, and in particular, novel molecules having twisted aryl groups are provided. In particular, the compounds include an aryl group at the ortho position relative to an amine nitrogen, thereby causing a twist within the compound from the plane of the aryl group due to the steric effect. As a result, this decreases the tendency of the molecules to pack closely and results in a higher solid state triplet energy due to reduced solid state π-stacking. Additionally, organic light emitting devices (OLEDs) comprising a layer including these novel compounds are provided.
US08716483B2 Compounds that are ERK inhibitors
Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
US08716481B2 Process for the preparation of 6-substituted-1-(2H)-isoquinolinones
The present invention relates to a process for making 6-substituted-1-(2H)-isoquinolinone derivatives of formula (I) wherein R1 and n are as described in the specification. The present invention further relates to novel intermediates which are used in the process according to the invention and to processes for preparing such intermediates.
US08716478B2 Boron-containing small molecules
Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions and/or helminth-associated diseases are disclosed.
US08716476B2 Process for the preparation of alfuzosin hydrochloride
A process for preparing alfuzosin or a salt thereof comprising: (a) condensing 4-amino-2-chloro-6,7-dimethoxyquinazoline with 3-methylaminopropionitrile in the presence of a polar aprotic solvent selected from the group consisting of diglyme, dimethyl formamide, t-butanol, hexamethylphosphoramide or mixtures thereof to form N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N-methyl-2-cyanoethylamine (b) hydrogenating the N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N-methyl-2-cyanoethylamine using a hydrogenating agent under a pressure of less than 10 kg/cm2 to form N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine and optionally converting the N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine to an acid addition salt thereof; and (c) converting tetrahydrofuroic acid to an intermediate form and condensing the intermediate form with the N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine or with the acid addition salt to yield alfuzosin base, and optionally converting alfuzosin base to a salt of alfuzosin.
US08716473B2 Substituted benzotriazines and quinoxalines as inhibitors of P7OS6 kinase
The invention provides compounds of the formula (1): or salts or tautomers thereof; wherein X1 is N or N+(O−); X2 is N or CH; Q is a C1-3 alkylene group; R1 is selected from hydrogen, C1-4 hydrocarbyl and hydroxy-C2-4 hydrocarbyl; R2, R3 and R4 are the same or different and each is selected from hydrogen, fluorine, chlorine and methyl; Ar1 is an optionally substituted monocyclic 5 or 6-membered aryl or heteroaryl ring containing 0, 1 or 2 heteroatom ring members selected from O, N and S, or a naphthyl ring and Ar2 is an optionally substituted monocyclic 5 or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S. The compounds of formula (1) are inhibitors of p70S6 kinase and are useful in the treatment of proliferative diseases.
US08716471B2 Process for the preparation of tetrazine derivatives
The present invention provides a process for the preparation of a tetrazine derivative of formula (I), or a pharmaceutically acceptable salt thereof wherein R1 represents a hydrogen atom, a straight or branched C1-C6 alkyl group, C2-C6 alkenyl group or C2-C6 alkynyl group, which C1-C6 alkyl group, C2-C6 alkenyl group and C2-C6 alkynyl group is unsubstituted or substituted with 1, 2 or 3 substituents selected from halogen atoms, straight or branched C1-C4 alkoxy groups, C1-C4 alkylthio groups, C1-C4 alkylsulphinyl groups, C1-C4 alkylsulphonyl groups and phenyl groups, which phenyl groups are unsubstituted or substituted with one or more substituents selected from C1-C4 alkyl groups, C1-C4 alkoxy groups and nitro groups; or R1 represents a C3-C8 cycloalkyl group; and R2 represents a group of formula —(C═O)NR3R4, wherein R3 and R4 are independently selected from hydrogen atoms, C1-C4 alkyl groups, C2-C4 alkenyl groups and C3-C8 cycloalkyl groups, which process comprises: i) providing a compound N of formula (III), wherein R1 is as defined; R1—N═C═O ii) absorbing the compound of formula (III) into a solvent to obtain a solution of the compound of formula (III); iii) adding to the thus obtained solution a compound of formula (II), to obtain a compound of formula (I), as defined above, wherein R2 is as defined above; iv) decomposing any excess compound of formula (III) remaining by addition of water; and v) optionally salifying the thus obtained compound with a pharmaceutically acceptable acid, or base.
US08716469B2 Synthetic oligosaccharides for Moraxella vaccine
The present invention provides synthetic Moraxella catarrhalis lipooligosaccharide (LOS)-based oligosaccharides and conjugates containing various M. catarrhalis serotype-specific oligosaccharide antigens or various core M. catarrhalis oligosaccharide structures or motifs corresponding to one or more of the three major serotypes and/or members within a given serotype. The oligosaccharides may be synthesized by a chemical assembly methodology relying on a limited number of monosaccharide and disaccharide building blocks. The invention further provides M. catarrhalis LOS-based immunogenic and immuno-protective compositions and antibodies derived therefrom for diagnosing, treating, and preventing infections caused by M. catarrhalis.
US08716454B2 Solid compositions
The present invention features solid compositions comprising Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, in an amorphous form. In one embodiment, Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, is formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.
US08716448B2 Coagulation factor VII compositions and methods of making and using same
The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.
US08716447B2 Optically-based stimulation of target cells and modifications thereto
Stimulation of target cells using light, e.g., in vivo or in vitro, is implemented using a variety of methods and devices. One example involves a vector for delivering a light-activated molecule comprising a nucleic acid sequence that codes for light-activated molecule. The light-activated molecule includes a modification to a location near the all-trans retinal Schiff base, e.g., to extends the duration time of the open state. Other aspects and embodiments are directed to systems, methods, kits, compositions of matter and molecules for ion channels or pumps or for controlling currents in a cell (e.g., in in vivo and in vitro environments).
US08716443B2 Sub-region of a plasmodium protein with improved vaccine potential, and medical uses thereof
The present application relates to a sub-region of a Plasmodium protein, with improved vaccine potential, and to medical uses thereof, notably for treatment or diagnosis of malaria. The present invention notably provides unstructured or unfolded polypeptides deriving from the PFF0165c protein of P. falciparum 3D7. The polypeptides of the invention have a high antigenicity, a high immunogenicity, have a high parasite-killing activity in the ADCI assay, and are strongly associated with clinical protection against malaria, and. The present invention thereby provides a vaccine for the palliative and/or curative treatment of malaria, which is specifically intended for infants, toddlers, children under the age of 5, pregnant women.
US08716440B2 Method of liberating and recovering peptide
A novel method capable of liberating a peptide from a complex of peptide and albumin and the associated method of recovering the peptide are provided. When a liquid sample containing a complex of peptide and albumin undergoes heat treatment, a self-aggregate of albumin formed in the liquid sample. The peptide is simultaneously liberated from the complex and recovered by removing the self-aggregate from the liquid sample.
US08716439B2 Method of producing peptide
The present invention is related to a method of producing a peptide, characterized in contacting a reaction mixture with a base after a condensation reaction to hydrolyze while a basic condition is maintained until a ratio of a remaining unreacted active ester of an acid component is decreased to 1% or less in a liquid phase peptide synthesis method. According to the invention, a target peptide of high purity can be simply and efficiently produced by a continuous liquid phase synthesis method. Further, the present invention is related to a method of producing a peptide, characterized in using an amide-type solvent immiscible with water in a liquid phase peptide synthesis method. According to the invention, various peptides can be produced by the liquid phase synthesis method without being restricted by the amino acid sequence of the target peptide.
US08716437B2 Identification of toxin ligands
The disclosure relates to a method and system of screening for ligands which specifically bind to receptors. The method comprises expressing at least one receptor. The at least one receptor is contacted with a sample comprising at least one ligand. Whether the ligand selectively binds to the receptor is determined.
US08716433B2 Aramid copolymer
The invention concerns polymer comprising residues of 2-(4-amino phenyl)-5 (6) amino benzimidazole (DAPBI), paraphenylene diamine, and terephthaloyl dichloride, the polymer having a IPC peak block ratio of 1.45 to 1.47 and an inherent viscosity of greater than 2 dl/g.
US08716432B2 Process for forming an aramid copolymer
The invention concerns processes for forming a polymer comprising residues of 2-(4-amino phenyl)-5(6) amino benzimidazole (DAPBI), paraphenylene diamine (PPD), and terephthaloyl dichloride, comprising the steps of: (a) forming a slurry of DAPBI in a solvent system comprising an organic solvent and an inorganic salt; (b) adding terephthaloyl dichloride to the slurry terephthaloyl dichloride in the amount of up to one-half mole for every mole of DAPBI in the slurry; (c) agitating the slurry to react the DAPBI and terephthaloyl dichloride to form an oligomeric solution; (d) adding PPD to the oligomeric solution and agitating until substantially all of the PPD is dissolved, (e) adding terephthaloyl dichloride in an amount of greater than one mole for every mole of PPD in the solution to form a prepolymer solution; and (e) agitating the prepolymer solution to form a polymer.
US08716431B2 Process for preparing aramid copolymer
The invention concerns processes for forming a polymer comprising residues of 2-(4-amino phenyl)-5(6)amino benzimidazole (DAPBI), paraphenylene diamine, and terephthaloyl dichloride, comprising the steps of: (a) forming a slurry of DAPBI and paraphenylene diamine in a solvent system comprising an organic solvent and an inorganic salt; and (b) adding a stoichiometric amount of terephthaloyl dichloride to the slurry in a single addition and allowing the formation of the polymer.
US08716425B2 Method of reducing stress relaxation in polymer articles and articles formed thereby
A method of improving the mechanical properties of polymers is described. The method involves heat treating the polymer at a temperature below the glass transition temperature in a wet or in a dry environment. Polymer articles capable of moisture uptake in humid environments, as well as polymer articles less susceptible to moisture uptake, have improved mechanical properties, particularly improved stress relaxation behavior and set properties, when treated in accord with the heat treatment method.
US08716416B2 Magnesium-compound supported nonmetallocene catalyst and preparation thereof
The present invention relates to a magnesium compound-supported nonmetallocene catalyst, which is produced by directly contacting a catalytically active metallic compound with a nonmetallocene ligand-containing magnesium compound, or by directly contacting a nonmetallocene ligand with a catalytically active metal-containing magnesium compound, through an in-situ supporting process. The process is simple and flexible. In the process, there are many variables in response for adjusting the polymerization activity of the catalyst, and the margin for adjusting the catalyst load or the catalyst polymerization activity is broad. The magnesium compound-supported nonmetallocene catalyst according to this invention can be used for olefin homopolymerization/copolymerization, in combination with a comparatively less amount of the co-catalyst, to achieve a comparatively high polymerization activity. Further, the polymer product obtained therewith boasts high bulk density and adjustable molecular weight distribution.
US08716408B2 Method for producing modified propylene polymer
Disclosed is a method for producing a modified propylene polymer that exhibits low flowability and also exhibits little fluctuation in melt flow rate compared with the melt flow rate of the propylene polymer before modification, the method involving a heat treatment step of subjecting a mixture comprising 100 parts by weight of a propylene polymer (A), from 0.1 to 50 parts by weight of an ethylenically unsaturated bond-containing compound (B), and from 0.01 to 20 parts by weight of an organic peroxide (C) whose decomposition temperature at which the half-life thereof becomes 1 minute is lower than 120° C. to heat treatment by using an extruder at a temperature lower than the decomposition temperature of the organic peroxide (C) at which the half-life thereof becomes 1 minute.
US08716407B2 Microgel containing vulcanizable composition based on hydrogenated nitrile rubber
A novel vulcanizable composition is provided, based on at least one hydrogenated nitrile rubber, on at least one peroxide, on at least one unsaturated carboxylic acid and/or salts thereof, and also on specific microgels. These vulcanizable compositions can be used to obtain vulcanized products which can in particular be used for drive belts, roll coverings, hoses and cables.
US08716402B2 Barrier coating comprising a polyurethane dispersion and elastomeric material
A barrier coating comprising a polyurethane dispersion and an elastomeric material is disclosed. The polyurethane comprises at least 30 weight percent of meta-substituted aromatic material. Methods for improving barrier using the coatings are also disclosed.
US08716399B2 Polysaccharide-grafted polyethylenimine as a gene carrier
The present invention discloses a gene carrier and the preparation method thereof. Chondroitin sulfate (CS) is reacted with methacrylic anhydride (MA) to form chrondroitin sulfate-methacrylate (CSMA), which is further covalently bound with polyethylenimine (PEI) via the Michael addition to produce a CSMA-PEI gene carrier. The CSMA-PEI gene carrier can effectively reduce the cytotoxicity of PEI and enhance the transfection efficiency of PEI.
US08716395B2 Light-emitting-element encapsulating composition, light-emitting diode and liquid-crystal display device
An encapsulating composition for a light emitting element, a light emitting diode (LED) and a liquid crystal display device (LCD) are provided. A silicone-cured product included as a main ingredient and a conductivity-providing agent having excellent compatibility and capable of providing superior conductivity can be used to significantly reduce the surface resistivity of the silicone-cured product. Therefore, the encapsulating composition for a light emitting element, the LED and the LCD can be useful in solving the problems regarding attachment of a foreign substance such as dust due to static electricity, and degradation of transparency since the composition has low surface resistivity when used as a semiconductor encapsulation material for an LED, and also in providing a cured product having excellent properties such as light resistance, heat resistance, durability and optical transparency.
US08716392B2 Nonfluorinated polyurethanes and methods of making and using thereof
Described herein are nonfluorinated polyurethanes having (a) a plurality of silicon polyol units and (b) a plurality of organic polyol units, wherein at least one of the organic polyol units has an ionizable group. The polyurethanes can be applied to a variety of different articles. The polyurethanes can impart a number of beneficial properties to an article including, but not limited to, liquid repellency, stain resistance, and bleach resistance. The nonfluorinated polyurethanes described herein are as effective or perform substantially better than fluorinated compounds currently used in the market. Methods for making the nonfluorinated polyurethanes are also described herein.
US08716388B2 Polycarbonate nanocomposites
Polycarbonate nanocomposites comprising a polycarbonate matrix having non-oxidized metal nanoparticles dispersed therein are disclosed. The polycarbonate nanocomposite is produced by a process comprising forming a reaction mixture comprising a dihydroxy compound, an activated carbonate, a metal precursor, and a solvent; and in-situ polymerizing the reaction mixture to form a nanocomposite comprising a polycarbonate matrix and metal nanoparticles dispersed therein. The metal precursor comprises a metal selected from a specified group. The nanocomposites have improved mechanical, optical, electrical and/or magnetic properties. Also disclosed are articles formed from such polycarbonate nanocomposites.
US08716383B2 Material for the prevention of bedsores
A method for manufacturing a protective layer for protecting skin and tissues in a vicinity of the skin includes the steps of: forming a mixture comprising approximately 15% of dimethyl-vinyl-terminated polydimethylsiloxane with a viscosity greater than 20,000 mPa·s, approximately 25% of dimethyl-vinyl-terminated polydimethylsiloxane with a viscosity between 200 and 20,000 mPa·s, approximately 45% of trimethyl-terminated polydimethylsiloxane, approximately 12% of trimethylsiloxy-treated pyrogenic silica, and approximately 3% of dimethyl-hydrogen-terminated co-polydimethylsiloxane-polymethyl-hydrogen-siloxane; polymerizing at least partially the mixture to obtain a polymer gel; and forming the protective layer using the polymer gel. The polymer gel has, at a temperature of 35° C. and when a shearing rate varies between 0 and 100 rad/s, a shear storage modulus or elastic component varying from 11,000 to 20,000 Pa, a shear loss modulus or viscous component varying from 700 to 8,000 Pa, and a Tan Delta varying from 0.06 to 0.38.
US08716382B2 Thermoplastic polyester elastomer resin composition and molding article comprising the same
Disclosed are a thermoplastic polyester elastomer resin composition and a molded article comprising the same. More specifically, disclosed is a thermoplastic polyester elastomer resin composition which comprises a glycidyl group-modified ethylene-octene based copolymer resin, as a chain extension/hydrolysis resistance agent for blow and extrusion molding to improve melt viscosity, and increases a molecular weight through reaction extrusion and thus exhibits superior heat resistance, weather resistance, heat aging resistance, hydrolysis resistance, fatigue resistance properties, melt viscosity and parison stability, and in particular, exhibits superior blow molding, contains no gel, reduces production of odor-causing substances such as volatile organic compounds (TVOC) during blow molding, and maintains a balance between physical properties, moldability and operation environments.
US08716381B2 Thermoplastic molding composition
The present invention relates to the use of a molding composition for producing a feed container consisting essentially of a copolymer composed of (A) from 5 to 60% by weight of units of the formula (I) (B) from 40 to 95% by weight of units of the formula (II) where the total of the proportions by weight is 100% by weight, based on the copolymer, and where the demolding force of the molding composition is from 1800 to 2800 N.
US08716379B2 Non halogen flame retardant thermoplastic polyurethane
Flame retardant thermoplastic polyurethane (TPU) compositions are disclosed having a flame retardant package comprising an organo-phosphinate component, an organo-phosphate component, and a polyhydric alcohol. The flame retardant components may be present in an amount from about 5 to about 40 weight percent of the phosphinate compound; from about 5 to about 20 weight percent of the phosphate compound, and from about 0.1 to about 15 weight percent of the polyhydric alcohol, based on the total weight of the TPU composition. Processes are disclosed to make the TPU compositions and to make wire and cable constructions employing the TPU compositions as the jacket of the wire and cable constructions. The TPU compositions exhibit excellent flame retardant capabilities as measured by Limited Oxygen Index testing and/or UL 94 Vertical Burn tests.
US08716376B2 Rubber composition and hose using the same
The present invention provides a rubber composition capable of forming an inner tube and/or an outer cover having high adhesion to a brass-plated wire and having excellent heat resistance, and oil resistance in a hose using a brass-plated wire as a reinforcing layer. The rubber composition includes 100 parts by mass of a rubber component (A) that includes ethylene-(meth)acrylate copolymer rubber and/or hydrogenated acrylonitrile-diene copolymer rubber, 1 to 30 parts by mass of a phenol resin (B), 1 to 30 parts by mass of silica (C), 0.1 to 5 parts by mass of a triazine compound (D) represented by the following formula (I), and 1 to 15 parts by mass of an organic peroxide (E) (in the formula (I), R represents a mercapto group, alkoxy group, monoalkylamino group, dialkylamino group, monocycloalkylamino group, dicycloalkylamino group, or N-alkyl-N-arylamino group).
US08716374B2 Colour-stable LED substrates
The present invention relates to a composition comprising, (a) a transparent or translucent polymer or polymer blend in an amount which together with components b) to g) gives 100 wt. %, (b) optionally 0 ppm to 2500 ppm of one or more stabilizers, (c) 0.001 ppm to 10,000 ppm of at least one dye comprising structure 1a and/or 1b, (d) 0.001 ppm to 10,000 ppm of at least one dye selected from the group consisting of dyes differing from dyes having structure 1a and/or 1b based on perinone or indanthrone and dyes based on a phthalocyanine or phthalocyanine complex, (e) optionally 0 ppm to 3000 ppm of one or more release agents, (f) optionally 0 ppm to 6000 ppm of one or more UV absorbers, and (g) optionally 0 ppm to 500,000 ppm of one or more further additives.
US08716367B2 Epoxy functional acrylic coating powders and powder coatings therefrom having improved filiform corrosion resistance
The present invention provides coating powders that enable improved filiform corrosion resistance in clear or tinted clear coating comprising an epoxy functional acrylic copolymer component having a Tg of from 40° C. to 90° C. and chosen from a copolymer or copolymer mixture that comprises, based on the total weight of copolymerized monomers in the epoxy functional acrylic copolymer component, i) from 10 to 40 wt. % of one or more epoxy functional unsaturated monomer, e.g. glycidyl (meth)acrylate; ii) from 2.0 wt. % to 13 wt. %, preferably 12 wt. % or less, or, more preferably, 6 wt. % or less, of one or more hydrophobic acrylic monomer that has a mass solubility in water of 3.5 g/L or less and which would itself form a homopolymer having a glass transition temperature (Tg) of 50° C. to 175° C., e.g. a bicycloalkyl(meth)acrylate, and iii) the remainder of one or more nonionic comonomer that is not a hydrophobic acrylic monomer ii), e.g. methyl methacrylate; one or more crosslinker for the thermosetting acrylic copolymer; and, optionally, one or more adhesion promoter, e.g. epoxy resin, a light stabilizer, an ultraviolet (UV) absorber, and/or a hydrophobic submicron particle.
US08716366B2 Process for the preparation of carbon black/silica/nanoclay master batch from fresh natural rubber latex
The present invention relates to a process for preparing tri-filler incorporated natural rubber master batch. The fillers used in the present invention are carbon black, silica and nano-clay (modified montmorillonite clay, Cloisite 93 A). The process of preparing fillers incorporated master batch involves preparation of the individual filler dispersions by mixing each filler with surfactants. Further fresh rubber latex is soap sensitized by mixing it with surfactant. The filler dispersions are added to the soap sensitized rubber latex slowly under stirring to form the master mix. Then the master mix is coagulated by the addition of acid to form coagulum. The coagulum is dewatered and dried to obtain filler incorporated natural rubber master batch.
US08716363B2 Biodegradable putty compositions and implant devices, methods, and kits relating to the same
Disclosed are phospholipid based compositions and implant devices, as well as methods and kits that include such compositions or components thereof. In particular, the present compositions include a polymer component such as a poloxamer or PEG component and a phospholipid component, such as a Phosal. The present compositions may include at least one additional component, such as granules, powder and/or particulates. The present compositions may further include one or more bone graft materials and/or active ingredients. The compositions may be used on their own or incorporated on or in a surgical implant.
US08716360B2 Curing-type coating-agent composition
A curing-type coating-agent composition according to the present invention contains: Component (A) including a urethane adduct compound exhibiting weatherability in an amount of from 99 to 65 parts by mass; Component (B) comprising a reaction product between a colloidal silica and an alkoxysilane compound having a maleimide group in an amount of from 1 to 35 parts by mass; a radical-polymerization initiator serving as Component (C) in an amount of from 0.1 to 10 parts by mass; an ultraviolet absorber serving as Component (D) in an amount of from 1 to 12 parts by mass; and an organic solvent serving as Component (E) in an amount of from 10 to 1,000 parts by mass; with respect to a sum of Component (A) and Component (B) being taken as 100 parts by mass.The composition according to the present invention demonstrates excellent wear resistance and weatherability as a coating agent for plastic substrate, or the like, which is employed outside.
US08716354B2 Propofol compositions and methods for reducing pain associated with propofol injection
The present invention pertains to pharmaceutical formulations containing propofol, methods for making such formulations, and methods for administering propofol at a pH above about 6.5, wherein the pain normally associated with propofol administration is reduced.
US08716352B1 Tannin formulation for treating GI spasms
Methods of treating gastrointestinal spasms are provided. For example, methods of treating gastrointestinal spasms are provided, such methods not requiring the use of systemic drugs that have shown to (i) provide slow relief, (ii) cause adverse side effects, (iii) limit activities, (iv) worsen existing gastrointestinal conditions, (v) be unrecommended in several gastrointestinal conditions that include gastrointestinal spasms, or (vi) be unrecommended in the absence of diarrhea.
US08716351B1 Methods of treating gastrointestinal spasms
Methods of treating gastrointestinal spasms are provided. For example, methods of treating gastrointestinal spasms are provided, such methods not requiring the use of systemic drugs that have shown to (i) provide slow relief, (ii) cause adverse side effects, (iii) limit activities, (iv) worsen existing gastrointestinal conditions, (v) be unrecommended in several gastrointestinal conditions that include gastrointestinal spasms, or (vi) be unrecommended in the absence of diarrhea.
US08716349B2 Compositions and methods for the treatment of somatosensory disorders
A method of combating a somatosensory disorder in a subject, comprising administering to the subject an effective amount of a composition comprising bupranolol and/or pharmaceutically acceptable derivative(s) thereof. Compositions useful for such administration are described, including salts, esters, solvates, etc. of tert-butyl[3-(2-chloro-5-methylphenoxy)-2-hydroxypropyl]amine, in which such salt, ester, solvate, etc. compound is in enantiomeric excess or homoenantiomeric in the R isomer thereof, or is formulated with racemic mixtures of the R and S stereoisomers of the salts, esters, solvates, etc. of tert-butyl[3-(2-chloro-5-methylphenoxy)-2-hydroxypropyl]amine. Combination therapy compositions of opioid receptor agonists and such compounds are also described. A method is disclosed of referential genotypic screening of candidate subjects in connection with therapeutic intervention using the compositions of the disclosure to combat the somatosensory disorder.
US08716348B2 Formoterol/steroid bronchodilating compositions and methods of use thereof
Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof, and a steroidal anti-inflammatory agent. Methods for treatment, prevention, or amelioration of one or more symptoms of bronchoconstrictive disorders using the compositions provided herein are also provided.
US08716342B2 Method for preparing molecular complexes between adapalene and cyclodextrins
A method for preparing molecular complexes between Adapalene and cyclodextrins using the technology of dense fluids under pressure, especially that of CO2 is described.
US08716339B2 Two-part disinfectant system and related methods
The present disclosure is drawn to a disinfectant system which can be used to disinfect surfaces. The system includes a first chamber containing a first solution and a second chamber containing a second solution. The first solution can include an alcohol, an organic carboxylic acid, and from 0.01 ppm, to 1,000 ppm by weight of a transition metal or alloy thereof based on the first solution weight content. The second solution can include hydrogen peroxide. The system further includes a dispenser through which the system is configured to mix and dispense the first solution and the second solution immediately before being dispensed. A peracid composition is formed upon mixing of the first and second solutions.
US08716335B2 Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors
The present invention relates generally to substituted benzofurans, benzothiophenes, and indoles and their use as tubulin polymerization inhibitors.
US08716334B2 Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
Novel substituted cyclohexylidene-ethylidene-octahydro-indene compounds and compositions comprising the same are described. The compounds exhibit profound anti-proliferative effects, in comparison to other compounds known for their anti-cancer and anti-hyperproliferative ability. Methods of use of such compounds and compositions are described for treating a variety of cancers, inflammatory and other hyperproliferative diseases and disorders.
US08716326B2 Isoindolinone derivatives, preparation method thereof and a pharmaceutical composition comprising same
The present invention relates to an amide compound or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition comprising the same. The inventive amide compound facilitates bone formation and inhibits bone loss, and is therefore useful for preventing and treating bone disorders such as osteoporosis, osteodystrophy, bone fracture, periodontal disease, Paget's disease, bone metastasis, and rheumatoid arthritis.
US08716324B2 Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators
The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are tricyclic indeno-pyrrole compounds. These compounds are serotonin receptor (5-HT) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity).
US08716323B2 Cyclic protein tyrosine kinase inhibitors
Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.
US08716322B2 Compounds for enzyme inhibition
Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases associated with the proteasome. The peptide-based compounds include an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation. Oral administration of these peptide-based proteasome inhibitors is possible due to their bioavailability profiles.
US08716321B2 Methods for dosing an orally active 1,2,4-oxadiazole
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases associated with nonsense mutations. In particular, the invention relates to specific doses and dosing regimens for the use of 3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid in mammals having diseases associated with nonsense mutations.
US08716320B2 Antibacteriall heterocyclic ureas
The present invention provides novel heterocyclic urea compounds having useful antibacterial activity, pharmaceutical compositions comprising one or more of these compounds, methods of making the same, and methods of using the same.
US08716316B2 Positive allosteric modulators (PAM)
The present invention relates to phenylethynyl compounds of formula I wherein R1, R2, X, L, R3, R4, R4′, cyc, and n are as defined in the specification and claims and to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof. Compounds of formula I are positive allosteric modulators (PAM) of the metabotropic glutamate receptor subtype 5 (mGluR5). They are useful for the treatment of schizophrenia or cognitive diseases.
US08716310B2 Dual mechanism inhibitors for the treatment of disease
Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (IOP) may be achieved.
US08716303B2 N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
The present invention relates to N-(hetero)aryl-pyrrolidine derivatives of Formula I: which are JAK inhibitors, such as selective JAK1 inhibitors, useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.
US08716301B2 Methods for using extracellular adenosine inhibitors and adenosine receptor inhibitors to enhance immune response and inflammation
A method is provided herein to increase an immune response to an antigen. The method includes administering an agent that inhibits extracellular adenosine or inhibits adenosine receptors. Also disclosed are methods to increase the efficacy of a vaccine and to increase an immune response to a tumor antigen or immune cell-mediated tumor destruction.
US08716299B2 XIAP-targeted prostate cancer therapy
A treatment for prostate cancer using cyclin-dependent kinase inhibitors is provided. The effects of cyclin-dependent kinase inhibitors on the survival of prostate cancer cells was examined. Roscovitine, R-roscovitine, and CGP74514A were shown to induce the apoptosis of LNCaP and LNCaP-Rf cells, both of which express wild-type p53. The cyclin-dependent kinase inhibitors of the present invention induce the mitochondria-mediated apoptosis of prostate cancer cells by a dual mechanism: p53 accumulation and XIAP depletion.
US08716297B2 Chemical entities to be used for Wee1 inhibition for the treatment of cancer
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1, R2, R3, A, B, and n are defined in the description. The present invention relates also to compositions containing compounds of formula (I) which are useful for inhibiting kinases such as wee-1 and methods of treating diseases such as cancer.
US08716296B2 Inhibitors of protein kinases
Compounds of general formula (I): are useful as inhibitors of cyclin dependent kinases such as CDK9.
US08716290B2 Heterocyclic compounds and their uses
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
US08716286B2 Crystalline forms of (3R, 6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione
The present invention relates to crystalline forms of (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione benzenesulfonate salt and pharmaceutical compositions thereof. Also disclosed are processes for the preparation the above compounds and methods for use thereof.
US08716282B2 Imidazo[1,2-b]pyridazine derivatives and their use as PDE10 inhibitors
The present invention relates to novel imidazo[1,2-b]pyridazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which are useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.
US08716280B2 Bicyclic antibiotics
The antibacterial compound of formula I wherein X1, X3; X4 and X6, each independently of the others, represents a nitrogen atom or CR2, with the proviso that at least one of X1, X3; X4 and X6 represents a nitrogen atom; X2 represents C—H, C—(C1-C6alkyl), C—(C1-C6alkoxy), C-halogen, C—COOH; X5 represents C—H or C—(C1-C6alkyl), C-halogen; A1, A2, A3, R1 and R4 represent various substituents, G represents aryl or heteroaryl, which is unsubstituted or substituted which compounds show good activity against pathogenic bacteria.
US08716259B2 Oligonucleotide chelate complexes
The present disclosure describes the broadly active chelation of diverse divalent 2+ metal cations by any oligonucleotide (ON), regardless of size or modification. This chelation effect is specific to cations which are divalent (or of higher valency) and results in the formation of oligonucleotide chelate complexes which do not behave like salts. It is described herein a novel composition of an ON chelate complex prepared using any ON and a divalent metal cation and methods for the suppression of anti-coagulation and or subcutaneous injection site reactions and or improved tolerability with oligonucleotides by the use of ON chelate complexes during oligonucleotide administration.
US08716257B2 CMV gene products promote cancer stem cell growth
The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.
US08716255B2 Microrna compositions and methods for the treatment of myelogenous leukemia
The invention provides methods, uses, kits and compositions comprising a therapeutically effective amount of the microRNA miR-223 for treating myelogenous leukemia in a subject in need of such treatment. The invention further comprises methods encompassing the use of miR-223 for promoting the differentiation of a leukemia stem cell that is resistant to a differentiating agent, and a method of screening for candidate compounds capable of treating a myeloid leukemia by comparison of the therapeutic activity of the candidate compound with the therapeutic activity of miR-233.
US08716251B2 Pharmaceutical formulations containing an SGLT2 inhibitor
Pharmaceutical formulations are provided which are in the form of capsules or tablets for oral use and which include a medicament dapagliflozin or its propylene glycol hydrate and a pharmaceutical acceptable carrier therefor, which formulation is designed for immediate release.
US08716249B2 Compositions and methods for improving cardiovascular health
Compositions and methods for improving cardiovascular health in the elderly by delivering a selection of essential amino acids, phytosterols, stanols, and isoflavones, which may be supplemented with a low glycemic carbohydrate and/or a medium chain fatty acid.
US08716247B2 Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors in humans, using compounds based on small peptides. The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier.
US08716245B2 Tissue protective peptides and uses thereof
Provided herein are tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are generally located on or within the region of the cytokine receptor ligand that faces away from a receptor complex while the ligand is bound to the receptor. Also provide herein are fragments, chimeras, as well as peptides designed to mimic the spatial localization of key amino acid residues within the tissue protective receptor ligands, e.g., EPO; methods for treating or preventing a disease or disorder using tissue protective peptides; and methods for enhancing excitable tissue function using tissue protective peptides.
US08716242B2 β-hairpin peptidomimetics
β-Hairpin peptidomimetics of the general formula Cyclo(-Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11-Xaa12-Xaa13-Xaa14-Xaa15-Xaa16-), and pharmaceutically acceptable salts thereof, with Xaa 1-Xaa 16 being amino acid residues of certain types which are defined in the description and the claims, have CXCR4 antagonizing properties and prolonged half-lives in vivo and can be used for preventing HIV infections in healthy individuals or for slowing and halting viral progression in infected patients; or where cancer is mediated or resulting from CXCR4 receptor activity; or where immunological diseases are mediated or resulting from CXCR4 receptor activity; or for treating immunosuppression; or during apheresis collections of peripheral blood stem cells and/or as agents to induce mobilization of stem cells to regulate tissue repair. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
US08716241B2 ApoIII and the treatment and diagnosis of diabetes
The present invention provides methods of identifying candidate compounds for the treatment of type I diabetes and also provides methods for treating patients with type I diabetes and for limiting pancreatic beta cell apoptosis. The present invention also provides methods for diagnosing type I diabetes or a propensity to develop type I diabetes and methods for identifying diabetic patients to be treated with anti-apoCIII therapy.
US08716240B2 Erythropoietin: remodeling and glycoconjugation of erythropoietin
The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
US08716236B2 Inhibitors of IAP
Novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies and have the general formula I: wherein R1, R2, R3, R4, R5 and R6 are as described herein.
US08716235B2 Method for inhibiting metastasis by using anti-CCL3 antibodies
Methods and compositions are provided for inhibiting metastasis of a tumor in a subject, or of inhibiting progression of a primary tumor in a subject which requires macrophages for progression.
US08716234B2 Cytotoxins comprising modified bouganin toxin for the treatment of cancer
The invention provides modified forms of bouganin protein having biological activity and a reduced propensity to activate human T cells as compared to the non-modified bouganin protein. The invention also provides T-cell epitope peptides of bouganin, and modified T-cell epitope peptides of bouganin which have a reduced propensity to activate human T cells as compared to the non-modified T-cell epitope peptide. The invention also provides cytotoxins having the having a ligand that binds to a cancer cells attached to the modified bouganin proteins. Also provided are methods of inhibiting or destroying mammalian cancer cells using the cytotoxins of the invention and pharmaceutical compositions for treating human cancer.
US08716231B2 Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
The present invention is a method for the treatment of pain comprising administering to a subject in need thereof a therapeutically effective amount of one or more novel benzo-fused heterocycle sulfamide derivatives of formula (I) and formula (II) as described herein. The present invention is further directed to methods for the treatment of pain comprising co-therapy with analgesic agent(s) and a compound of formula (I) or formula (II) as described herein.
US08716228B2 GPR54 agonists or antagonists for treatment of diseases presenting behavioral abnormalities
Use of a GPR54 agonist or antagonist for the treatment of a disease or disorder presenting behavioral abnormalities associated with impairment of sensory gating function, and/or for treatment of depression, and/or for improving cognitive function is disclosed. In particular, the invention relates to the use of kisspeptin or a peptide thereof for the treatment of schizophrenia.
US08716224B2 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition, including Crohn's disease and ulcerative colitis, and cancer.
US08716223B2 Small survival-promoting/immunomodulatory peptide for treatment of brain damage, neurodegenerative disorders, and inflammatory disorders
A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided.
US08716217B2 Polyglutamic acids functionalized by cationic groups and hydrophobic groups and applications thereof, in particular therapeutic applications thereof
The present invention relates to novel biodegradable materials based on modified polyamino acids that are useful in particular in the vectorization of active principle(s) (APs). The invention is also directed to novel pharmaceutical, cosmetic, health-food or plant-protection compositions based on these polyamino acids.The aim of the invention is to provide a novel polymeric starting material which can be used for AP vectorization and which satisfy all the requirements: biocompatibility, biodegradability, ability to easily associate with or dissolve numerous active principles and to release these active principles in vivo. This goal is achieved by the present invention, which relates to novel polyglutamates modified by cationic groups, which, if they can be deprotonated, exhibit a pKa equal to or greater than 7, and by hydrophobic groups comprising from 8 to 30 carbon atoms.These polyglutamates modified by cationic groups are easily and economically converted into particles for the vectorization of active principles, these particles being themselves capable of forming stable aqueous colloidal suspensions. These modified polyglutamates exhibit the advantage of being less viscous than other analogous polymers while retaining an ability to associate proteins, such as insulin. Some are soluble in water at acidic pH and become insoluble at physiological pH (7.4) and should thus, during subcutaneous injection, precipitate on the site of injection.
US08716210B2 Material for cleaning a substrate
Material for cleaning using a tri-state body are disclosed. A substrate having a particle deposited thereon is provided. A tri-state body that has a solid portion, liquid portion, and a gas portion is generated. A force is applied over the tri-state body to promulgate an interaction between the solid portion and the particle. The tri-state body is removed along with the particle from the surface of the substrate. The interaction between the solid portion and the particle causes the particle to be removed along with the tri-state body.
US08716207B2 Solidification mechanism incorporating ionic liquids
A solid cleaning composition including an ionic liquid and a hardening agent is provided. The compositions are substantially free of alkyl phenol ethoxylates, including nonyl phenol ethoxylates. The solid cleaning compositions remain solid at room temperature despite the inclusion of ionic liquids, providing an effective, biorenewable, environmentally friendly alternative to nonyl phenol ethoxylate cleaning compositions.
US08716206B2 Acetic acid-capped estolide base oils and methods of making the same
Provided herein are compounds, including those of the Formula II in which n is an integer equal to or greater than 1; R2, is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R3, and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Also provided are compositions containing such compounds and methods of making both compounds and compositions thereof.
US08716205B2 Compositions for and methods of lubricating carcass conveyor
An improved lubricant for use with a conveyor in a meat packing plant meeting the requirements of (1) adequate lubricity, (2) “drip-resistance,” (3) safety, (4) rust resistance, (5) economy of manufacture and use, and (6) the ability to be removed by cleaning methods is provided by preparing a mixture of mineral oil, a fatty acid, a silicone oil, and a polybutene, each being acceptable for incidental contact with food, in certain minimum amounts and increasing the amounts of one or more of said components such that the improved lubricant has a viscosity of 20-160 centipoise. A method of improving a lubricant for use on a conveyor in a meat packing plant and a method of lubricating the conveyor are also disclosed.
US08716203B2 Water-soluble colonoscopy lubricant
Disclosed is a water-soluble colonoscopy lubricant essentially comprising Polyethylene Glycol 400; Propylene Glycol; and Glycerin. Distilled water may be added as needed to achieve a desired viscosity. Additional ingredients such as a preservative and a pH adjuster may also be added to the colonoscopy lubricant.
US08716200B2 Conveyor lubricants including emulsion of a lipophilic compound and an emulsifier and/or an anionic surfactant and methods employing them
The present invention relates to conveyor lubricant compositions including an emulsion of a lipophilic compound and also including an emulsifier and/or an anionic surfactant. The present invention also relates to methods employing such lubricant compositions. In an embodiment, the method includes applying the present lubricant composition to a conveyor with a non-energized nozzle.
US08716198B2 Prevention and remediation of water and condensate blocks in wells
The present invention relates to a method of removing and preventing water and condensate blocks in wells by contacting a subterranean formation with a composition comprising a low molecular weight fluorinated copolymer having perfluoro alkyl moieties which are no longer than C6. A fluorinated copolymer of low molecular weight of about 50,000 g/mol and a method of preparing the same are also disclosed.
US08716194B2 Identification of antigen or ligand-specific binding proteins
The present invention discloses novel methods for the generation, expression and screening of diverse collections of binding proteins such as antibodies or fragments thereof in vertebrate host cells in vitro, for the identification and isolation of ligand- or antigen-specific binding proteins. The methods disclosed herein allow the expression of diverse collections of binding proteins from at least one vector construct, which optionally can give rise to collections of diverse binding proteins upon transfer and expression into vertebrate host cells in situ.
US08716193B2 Panel for the detection and differentiation of renal cortical neoplasms
The present invention provides a novel, highly sensitive and specific probe panel which detects the type of renal cortical neoplasm present in a biopsy sample. As such, the invention permits diagnosis of the predominant subtypes of renal cortical neoplasms without the use of invasive methods. The present invention further provides a molecular cytogenetic method for detecting and analyzing the type of renal cortical neoplasm present in a renal biopsy sample.
US08716189B2 Method of producing superconductive oxide material
A method of producing a superconductive material involves the step (1) of applying a solution of an organic compound of metals, oxides of the metals forming a superconductive material, onto a support body to be subsequently dried, a provisional baking step (2) of causing organic components of the organic compound of the metals to undergo thermal decomposition, and a main baking process step (3) of causing transformation of the oxides of the metals into the superconductive material, thereby producing an epitaxially-grown superconductive coating material, wherein at the time of irradiation of a surface of the support body coated with the solution of the organic compound of the metals for forming the superconductive material, and/or of a surface of the support body, opposite to the surface coated with the solution of the organic compound of the metals, with the laser light, during a period between the steps (1) and (2).
US08716188B2 Structure to reduce electroplated stabilizer content
A superconducting article includes first and second stacked conductor segments. The first stacked conductor segment includes first and second superconductive segments and has a nominal thickness tn1. The second stacked conductor segment includes third and forth superconductive segments and has a nominal thickness tn2. The superconducting article further includes a joint region comprising a first splice connecting the first and third superconductive segments together and a second splice connecting the second and forth superconductive segments together. The first splice is adjacent to and bridged portions of the first and third superconductive segments along at least a portion of the joint region, and the second splice is adjacent to and bridged portions of the second and forth superconductive segments along at least a portion of the joint region. The joint region has a thickness tjr, wherein tjr is not greater than at least one of 1.8tn1 and 1.8tn2.
US08716185B2 Stabilized herbicidal composition
A stabilized herbicidal composition comprising fenoxaprop ester herbicide in combination with pyrasulfotole. The present disclosure also provides for a method of stabilizing herbicidal compositions.
US08716184B2 Herbicidal composition comprising the hydrates of saflufenacil and glyphosate or glufosinate
A herbicide combination comprising a) at least one herbicide (A) selected from the group consisting of glyphosate (A1) and its agrochemically compatible salts, and glufosinate (A2) and its agrochemically compatible salts, and b) a herbicide (B) which is a hydrate of the compound 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)-pyrimidinyl]-4-fluoro-N-[[methyl-(1-methylethyl)amino]sulfonyl]benzamide, and the use thereof for controlling harmful plants.
US08716183B2 Control of aquatic weeds with endothall and ALS-inhibiting agent
Described are preferred methods and compositions for controlling aquatic weeds that involve the use of an ALS-inhibiting herbicidal agent such as penoxsulam in combination with endothall. Preferred herbicidal combinations allow for enhanced control when treating a body of water to control a target weed population, such as hydrilla.
US08716182B2 Liquid aqueous crop protection formulations
The present invention relates to a novel liquid aqueous plant protection formulation which comprises a) at least one organic plant protectant with a water solubility of less than 5 g/l at 20° C.; b) at least one organic solvent with a water solubility of over 100 g/l at 20° C.; c) at least one organic solvent with a water solubility of from 2 to 100 g/l at 20° C.; d) at least one organic solvent with a water solubility of less than 2 g/l at 20° C.; e) at least one nonionic surfactant; f) at least one anionic surfactant; and g) water. The invention also relates to the use of the plant protection formulation for the treatment of plants and seed, to corresponding methods, and to treated seed.
US08716180B2 Method of reducing mycotoxin contamination of the harvest
The present invention provides a method of reducing mycotoxin contamination of a plant and/or harvested plant material, said method comprising treating plant propagation material with one or more fungicides, germinating or growing said plant propagation material to produce a plant, and harvesting plant material from said plant.
US08716178B2 One-ply two-sided thermal imaging labels
A print media representing a label is constructed having two components. A first component is capable of being thermally imaged on both a front and back side of the print media. The second component is affixed to the first component but capable of being separated there from. Also, the second component includes adhesive material along a portion of its backside to adhere the print media to an object.
US08716172B2 Exhaust gas catalyst composition
Catalyst composition represented by the general formula REVO/S wherein RE is at least one of the group of rare earth metals Y, Ce, Pr, Nd, Sm, Gd, Tb, Dy, Er and Yb in an amount of up to 6.0 wt.-%; V is vanadium in an amount of 0.2-2.5 wt.-%; O is oxygen in an amount of up to 3.5 wt.-%; and S is a support containing TiO2 in an amount of at least 70 wt.-%, with the rest being WO3 and optionally SiO2. This catalyst composition shows high removal efficiencies for NOx even after aging at 750° C.
US08716170B2 Eggshell catalyst and methods of its preparation
An eggshell catalyst useful for a Fischer-Tropsch (FT) synthesis or other reactions comprises a homogeneously dispersed transition metal and a promoter situated in an active phase in a precisely selected outer region of a catalyst pellet. The active phase region is controlled to a specific depth, which permits the control of the catalysts selectivity, for example, the size of the hydrocarbon chains formed in the FT process. A method of preparing these eggshell catalysts involves a non-aqueous synthesis where polar and non-polar solvents of relatively low vapor pressure are employed to define the depth of penetration of metal species in a refractory oxide substrate, which is followed by fixing and activating metallic catalytic species in the structure by calcination of the catalyst particles.
US08716165B2 Catalysts on substrates and methods for providing the same
A method for providing a catalyst on a substrate is disclosed comprising providing a first washcoat comprising a soluble washcoat salt species, a polar organic solvent, and an insoluble particulate material, contacting the first washcoat with a substrate to form a coated substrate, and then contacting the coated substrate with a second washcoat comprising an oxide or an oxide-supported catalyst to physisorb, chemisorb, bond, or otherwise adhere the oxide or the oxide-supported catalyst to the coated substrate. Also disclosed is a catalyst on a substrate comprising: a substrate; an anchor layer comprising a soluble washcoat salt species, a polar organic solvent, and an insoluble particulate material; and a second layer comprises an oxide or an oxide-supported catalyst. The catalyst on a substrate can be in either green or fired form.
US08716159B2 Non-destructive process for the elimination of silicon from alumina based materials
A method for eliminating silicon or silicon compounds in alumina based materials without destroying such alumina based materials enabling reutilization particularly in catalysts for hydrotreating processes, comprising: a) mixing alumina based solid material which contains silicon with an alcohol extraction agent at a temperature between 10 and 300° C., for 10 minutes to 96 hours to form a mixture; b) separating solids from the mixture by centrifugation, decantation or filtration to obtain separated solids; c) washing the separated solids with at least one of water, alcohol or an ammonium hydroxide solution to form washed solids; and d) drying the washed solids to obtain regenerated alumina based solid material.
US08716158B2 Method for regenerating a solid iodine filter
A method for regenerating a solid filter containing iodine in the form of silver iodide and/or iodate and possibly molecular iodine physisorbed, in a solid filter containing silver in the form of nitrate. The iodine is extracted from the filter by putting the filter into contact with a basic aqueous solution containing a reducing agent. The extraction is achieved at room temperature, and then the filter is separated from this basic aqueous solution. Next, silver is extracted from the filter by putting the filter into contact with an acid aqueous solution. The filter is then separated from the acid aqueous solution. Finally, the filter is impregnated with silver by putting the filter into contact with a silver nitrate solution and then drying the filter. This method can be used in nuclear installations, notably factories for reprocessing used nuclear fuels.
US08716156B1 Methods of forming fins for a FinFET semiconductor device using a mandrel oxidation process
One illustrative method disclosed herein includes forming a mandrel structure above a semiconductor substrate, performing an oxidation process to oxidize at least a portion of the mandrel structure so as to thereby define oxidized regions on the mandrel structure, removing the oxidized regions to thereby defined a reduced thickness mandrel structure, forming a plurality of fins on the reduced thickness mandrel structure and performing an etching process to selectively remove at least a portion of the reduced thickness mandrel structure so as to thereby expose at least a portion of each of the fins.
US08716155B2 Method to enhance charge trapping
Methods of improving charge trapping are disclosed. One such method includes forming an oxide-nitride-oxide tunnel stack and a silicon nitride layer on the oxide-nitride-oxide tunnel stack. This silicon nitride layer is implanted with ions. These ions may function as electron traps or as fields. The silicon nitride layer may be part of a flash memory device.
US08716154B2 Reduced pattern loading using silicon oxide multi-layers
Aspects of the disclosure pertain to methods of depositing conformal silicon oxide multi-layers on patterned substrates. The conformal silicon oxide multi-layers are each formed by depositing multiple sub-layers. Sub-layers are deposited by flowing BIS(DIETHYLAMINO)SILANE (BDEAS) and an oxygen-containing precursor into a processing chamber such that a relatively uniform dielectric growth rate is achieved across the patterned substrate surface. A plasma treatment may follow formation of sub-layers to further improve conformality and to decrease the wet etch rate of the conformal silicon oxide multi-layer film. The deposition of conformal silicon oxide multi-layers grown according to embodiments have a reduced dependence on pattern density while still being suitable for non-sacrificial applications.
US08716151B2 Method of fabricating semiconductor devices
The present disclosure relates to a method of fabricating semiconductor devices. In the method provided by the present invention, by filling with diblock copolymer a recess of an interlayer dielectric layer naturally formed between two gate lines and then performing a self-assembly process of the diblock copolymer, a small-sized contact hole precisely aligned with an doped area can be formed, and thus misalignment between the contact hole and the doped area can be eliminated or alleviated.
US08716149B2 Methods for fabricating integrated circuits having improved spacers
Methods for fabricating integrated circuits are provided. In an embodiment, a method for fabricating an integrated circuit includes providing a semiconductor substrate having a gate structure. An atomic layer deposition (ALD) process is performed to deposit a spacer around the gate structure. The ALD process includes alternating flowing ionized radicals of a first precursor across the semiconductor substrate and flowing a chlorosilane precursor across the semiconductor substrate to deposit the spacer.
US08716147B2 Manufacturing method of semiconductor device and substrate processing apparatus
Provided are a manufacturing method of a semiconductor device and a substrate processing apparatus. The manufacturing method of the semiconductor device includes: loading a plurality of substrates into a reaction vessel, which is configured by a process tube and a manifold that supports the process tube, and arranging the loaded substrates within the reaction vessel; pre-processing the plurality of substrates by supplying a pre-process gas from the manifold side toward the process tube side within the reaction vessel; main-processing the plurality of pre-processed substrates by supplying a main-process gas from the manifold side toward the process tube side within the reaction vessel; and unloading the plurality of main-processed substrates from the reaction vessel, wherein in pre-processing the plurality of substrates, the pre-process gas is supplied from at least one position in an area corresponding to the manifold, and at least one position in an upper area of an area corresponding to a substrate arrangement area.
US08716146B2 Low temperature etching of silicon nitride structures using phosphoric acid solutions
Provided are methods for processing semiconductor substrates. The methods involve etching silicon nitride structures using phosphoric acid solutions maintained at low temperatures, such as between about 110° C. and 130° C. These temperatures provide adequate etching rates and do not damage surrounding metal silicide and silicon oxide structures. The etching rates of silicon nitride may be 10 Angstroms per minute and greater. Lower temperatures also allow decreasing concentrations of phosphoric acid in the etching solutions, which in some embodiments may be less than 90 weight percent. As a result, more selective etching of the silicon nitride structures may be achieved. This selectivity may be as high as hundred times relative to the silicide and silicon oxide structures. The surface conductivity of the silicide structures may remain substantially unchanged by this etching process.
US08716142B2 Semiconductor device and method of manufacturing the same
Provided is a semiconductor device formed with a trench portion for providing a concave portion in a gate width direction and with a gate electrode provided within and on a top surface of the trench portion via a gate insulating film. At least a part of a surface of each of the source region and the drain region is made lower than other parts of the surface by removing a thick oxide film formed in the vicinity of the gate electrode. Making lower the part of the surface of each of the source region and the drain region allows current flowing through a top surface of the concave portion of the gate electrode at high concentration to flow uniformly through the entire trench portion, which increase an effective gate width of the concave portion formed so as to have a varying depth in a gate width direction.
US08716140B2 Method of forming micropattern, die formed by this method of forming micropattern, transfer method and micropattern forming method using this die
A micropattern is joined to a substrate (W1) by: a first group of covering step and micropattern forming step by etching in a transfer step; and a second group of covering step and micropattern forming step by etching in the transfer step.
US08716136B1 Method of forming a semiconductor structure including a wet etch process for removing silicon nitride
A method disclosed herein includes providing a semiconductor structure comprising a transistor, the transistor comprising a gate electrode and a silicon nitride sidewall spacer formed at the gate electrode. A wet etch process is performed. The wet etch process removes at least a portion of the silicon nitride sidewall spacer. The wet etch process comprises applying an etchant comprising at least one of hydrofluoric acid and phosphoric acid.
US08716132B2 Radiation-assisted selective deposition of metal-containing cap layers
A method for integrating metal-containing cap layers into copper (Cu) metallization of semiconductor devices to improve electromigration and stress migration in bulk Cu metal. In one embodiment, the method includes providing a patterned substrate containing Cu metal surfaces and dielectric layer surfaces, exposing the patterned substrate to a process gas comprising a metal-containing precursor, and irradiating the patterned substrate with electromagnetic radiation, where selective metal-containing cap layer formation on the Cu metal surfaces is facilitated by the electromagnetic radiation. In some embodiments, the method further includes pre-treating the patterned substrate with additional electromagnetic radiation and optionally a cleaning gas prior to forming the metal-containing cap layer.
US08716129B2 Method for manufacturing silicon carbide semiconductor device
A method for manufacturing a silicon carbide semiconductor device includes the step of forming a silicon dioxide film. The step of forming an electrode includes the steps of forming a metal film containing Al and Ti on the silicon carbide substrate, and heating the metal film. The step of heating the metal film has the steps of increasing temperature of the metal film from a temperature of less than 300° C. to a temperature of not less than 300° C. and not more than 450° C. with a first temperature gradient, holding the metal film within a temperature range of not less than 300° C. and not more than 450° C. with a second temperature gradient, and increasing the temperature of the metal film to a temperature of not less than 500° C. with a third temperature gradient. The second temperature gradient is smaller than the first temperature gradient and the third temperature gradient.
US08716127B2 Metal alloy cap integration
A metal interconnect structure, which includes metal alloy capping layers, and a method of manufacturing the same. The originally deposited alloy capping layer element within the interconnect features will diffuse into and segregate onto top surface of the metal interconnect. The metal alloy capping material is deposited on a reflowed copper surface and is not physically in contact with sidewalls of the interconnect features. The metal alloy capping layer is also reflowed on the copper. Thus, there is a reduction in electrical resistivity impact from residual alloy elements in the interconnect structure. That is, there is a reduction, of alloy elements inside the features of the metal interconnect structure. The metal interconnect structure includes a dielectric layer with a recessed line, a liner material on sidewalls, a copper material, an alloy capping layer, and a dielectric cap.
US08716123B2 Method of forming an integrated circuit device
A method of forming an integrated circuit device includes forming an under-bump metallurgy (UBM) layer overlying a semiconductor substrate. Next, a first photoresist film is formed on the UBM layer where the first photoresist film has a first photosensitivity and a first thickness. Additionally, the method includes forming a second photoresist film on the first photoresist film. Next, the method includes performing an exposure process on the second photoresist film and the first photoresist film. The method further includes removing an exposed portion of the second photoresist film to form a first opening. The method further also includes removing an exposed portion of the first photoresist film to expose a portion of the UBM layer. Furthermore, the method includes forming a copper layer in the first opening. The method also includes removing the second photoresist film and the first photoresist film where the copper layer forms a copper post.
US08716121B2 Ohmic electrode and method of forming the same
An ohmic electrode for a p-type SiC semiconductor, and a method of forming the ohmic electrode. The ohmic electrode has an ohmic electrode layer, which has an amorphous structure and which is made of a Ti(1-x-y)Si(x)C(y) ternary film of which a composition ratio is within a composition range that is surrounded by two lines and two curves expressed by an expression x=0 (0.35≦y≦0.5), an expression y=−1.120x+0.5200 (0.1667≦x≦0.375), an expression y=1.778(x−0.375)2+0.1 (0≦x≦0.375) and an expression y=−2.504x2−0.5828x+0.5 (0≦x≦0.1667) and that excludes the line expressed by the expression x=0. The ohmic layer is directly laminated on a surface of a p-type SiC semiconductor.
US08716120B2 High-k metal gate electrode structures formed by reducing a gate fill aspect ratio in replacement gate technology
When forming sophisticated high-k metal gate electrode structures on the basis of a replacement gate approach, the fill conditions upon filling in the highly conductive electrode metal, such as aluminum, may be enhanced by removing an upper portion of the final work function metal, for instance a titanium nitride material in P-channel transistors. In some illustrative embodiments, the selective removal of the metal-containing electrode material in an upper portion of the gate opening may be accomplished without unduly increasing overall process complexity.
US08716119B2 Methods of forming transistor gates
Some embodiments include methods of forming charge storage transistor gates and standard FET gates in which common processing is utilized for fabrication of at least some portions of the different types of gates. FET and charge storage transistor gate stacks may be formed. The gate stacks may each include a gate material, an insulative material, and a sacrificial material. The sacrificial material is removed from the FET and charge storage transistor gate stacks. The insulative material of the FET gate stacks is etched through. A conductive material is formed over the FET gate stacks and over the charge storage transistor gate stacks. The conductive material physically contacts the gate material of the FET gate stacks, and is separated from the gate material of the charge storage transistor gate stacks by the insulative material remaining in the charge storage transistor gate stacks. Some embodiments include gate structures.
US08716115B2 High productivity combinatorial dual shadow mask design
Dual shadow mask design can overcome the size and resolution limitations of shadow masks to provide capacitor structures with small effective areas. The capacitor structures have bottom and top electrode layers patterned using shadow masks, sandwiching a dielectric layer. The effective areas of the capacitors are the overlapping areas of the top and bottom electrodes, thus allowing small area sizes without subjected to the size limitation of the electrodes. The dual shadow mask design can be used in conjunction with high productivity combinatorial processes for screening and optimizing dielectric materials and fabrication processes.
US08716109B2 Chip package and fabrication method thereof
A chip package and a fabrication method thereof are provided according to an embodiment of the invention. The chip package contains a semiconductor substrate having a chip. A packaging layer is disposed over the semiconductor substrate. A spacer is disposed between the semiconductor substrate and the packaging layer, wherein a side surface consisting of the semiconductor substrate, the spacer and the packaging layer has a recess section. The method includes forming a plurality of spacers between a plurality of chips of a semiconductor wafer and a packaging layer, wherein each spacer corresponding to each chip is separated from each other and the spacer is shrunk inward from an edge of the chip to form a recess section and dicing the semiconductor wafer along a scribe line between any two adjacent chips to form a plurality of chip packages.
US08716107B2 Epitaxial lift off stack having a non-uniform handle and methods thereof
Embodiments of the invention generally relate to epitaxial lift off (ELO) thin films and devices and methods used to form such films and devices. In one embodiment, a method for forming a thin film material during an epitaxial lift off process is provided which includes forming an epitaxial material over a sacrificial layer on a substrate, adhering a non-uniform support handle onto the epitaxial material, and removing the sacrificial layer during an etching process. The etching process further includes peeling the epitaxial material from the substrate while forming an etch crevice therebetween and bending the support handle to form compression in the epitaxial material during the etching process. In one example, the non-uniform support handle contains a wax film having a varying thickness.
US08716102B2 Methods of forming isolation structures for semiconductor devices by performing a dry chemical removal process
A method includes forming a patterned mask comprised of a polish stop layer positioned above a protection layer above a substrate, performing at least one etching process through the patterned mask layer on the substrate to define a trench in the substrate, and forming a layer of silicon dioxide above the patterned mask layer such that the layer of silicon dioxide overfills the trench. The method also includes removing portions of the layer of silicon dioxide positioned outside of the trench to define an isolation structure, performing a dry, selective chemical oxide etching process that removes silicon dioxide selectively relative to the material of the polish stop layer to reduce an overall height of the isolation structure, and performing a selective wet etching process to remove the polish stop layer selectively relative to the isolation region.
US08716088B2 Scavenging metal stack for a high-K gate dielectric
A semiconductor structure is provided. The structure includes a semiconductor substrate of a semiconductor material and a gate dielectric having a high dielectric constant dielectric layer with a dielectric constant greater than silicon. The gate dielectric is located on the semiconductor substrate. A gate electrode abuts the gate dielectric. The gate electrodes includes a lower metal layer abutting the gate dielectric, a scavenging metal layer abutting the lower metal layer, an upper metal layer abutting the scavenging metal layer, and a silicon layer abutting the upper metal layer. The scavenging metal layer reduces an oxidized layer at an interface between the upper metal layer and the silicon layer responsive to annealing.
US08716078B2 Method and system for a gallium nitride vertical JFET with self-aligned gate metallization
A semiconductor device includes a III-nitride substrate and a first III-nitride epitaxial layer coupled to the III-nitride substrate and comprising a drift region, a channel region, and an extension region. The channel region is separated from the III-nitride substrate by the drift region. The channel region is characterized by a first width. The extension region is separated from the drift region by the channel region. The extension region is characterized by a second width less than the first width. The semiconductor device also includes a second III-nitride epitaxial layer coupled to a top surface of the extension region, a III-nitride gate structure coupled to a sidewall of the channel region and laterally self-aligned with respect to the extension region, and a gate metal structure in electrical contact with the III-nitride gate structure and laterally self-aligned with respect to the extension region.
US08716076B2 Method for fabricating a semiconductor device having an epitaxial channel and transistor having same
A transistor having an epitaxial channel and a method for fabricating a semiconductor device having an epitaxial channel, the method including forming a hardmask on a substrate and forming an opening in the hardmask. The opening is geometrically characterized by a long dimension and a short dimension, and the opening is arranged in a predetermined manner relative to the channel region of a transistor. An epitaxial material is formed in the opening that induces strain in substrate regions proximate to the epitaxial material. The epitaxial material is confined to the opening, such that an epitaxial channel is formed. A transistor is fabricated in proximity to the epitaxial channel, such that the strain induced in the substrate provides enhanced transistor performance. By confining the epitaxial material to a predefined channel in the substrate, plastic strain relaxation of the epitaxial material is minimized and a maximum amount of strain is induced in the substrate.
US08716075B2 Floating body field-effect transistors, and methods of forming floating body field-effect transistors
In one embodiment, a floating body field-effect transistor includes a pair of source/drain regions having a floating body channel region received therebetween. The source/drain regions and the floating body channel region are received over an insulator. A gate electrode is proximate the floating body channel region. A gate dielectric is received between the gate electrode and the floating body channel region. The floating body channel region has a semiconductor SixGe(1-x)-comprising region. The floating body channel region has a semiconductor silicon-comprising region received between the semiconductor SixGe(1-x)-comprising region and the gate dielectric. The semiconductor SixGe(1-x)-comprising region has greater quantity of Ge than any quantity of Ge within the semiconductor silicon-comprising region. Other embodiments are contemplated, including methods of forming floating body field-effect transistors.
US08716070B2 Fabrication method of package structure having MEMS element
A fabrication method of a package structure having at least an MEMS element is provided, including: preparing a wafer having electrical connection pads and the at least an MEMS element; disposing lids for covering the at least an MEMS element, the lids having a metal layer formed thereon; electrically connecting the electrical connection pads and the metal layer with bonding wires; forming an encapsulant for covering the lids, bonding wires, electrical connection pads and metal layer; removing portions of the encapsulant to separate the bonding wires each into first and second sub-bonding wires, wherein top ends of the first and second sub-bonding wires are exposed, the first sub-bonding wires electrically connecting to the electrical connection pads, and the second sub-bonding wires electrically connecting to the metal layer; forming metallic traces on the encapsulant for electrically connecting to the first sub-bonding wires; forming bumps on the metallic traces; and performing a singulation process.
US08716068B2 Method for contacting agglomerate terminals of semiconductor packages
In fabricating a semiconductor device first layers are formed of sintered bondable and solderable metal on a carrier strip. The first layers are patterned into first pads and second pads. A set of first pads is surrounding each second pad. The first pads are spaced from the second pad by gaps. The patterned layers are formed of agglomerate metal vertically on the first layers of sintered bondable and solderable metal of the first pads and of the second pad. The second layers are formed of sintered bondable and solderable metal vertically on the layers of agglomerate metal of the first pads.
US08716066B2 Method for plating a semiconductor package lead
A method of forming a packaged semiconductor device includes loading an array of package sites in position for saw singulation, saw singulating the array of package sites, and performing a non-electrolytic plating operation on exposed lead tips of individual packages from the array of package sites as the array of package sites is saw singulated.
US08716061B2 Semiconductor device and method for manufacturing the same
In a thin film transistor which uses an oxide semiconductor, buffer layers containing indium, gallium, zinc, oxygen, and nitrogen are provided between the oxide semiconductor layer and the source and drain electrode layers.
US08716060B2 Confined resistance variable memory cell structures and methods
Confined resistance variable memory cell structures and methods are described herein. One or more methods of forming a confined resistance variable memory cell structure includes forming a via in a memory cell structure and forming a resistance variable material in the via by performing a process that includes providing a germanium amidinate precursor and a first reactant to a process chamber having the memory cell structure therein and providing an antimony ethoxide precursor and a second reactant to the process chamber subsequent to removing excess germanium.
US08716059B2 Combined conductive plug/conductive line memory arrays and methods of forming the same
Memory arrays and methods of forming the same are provided. One example method of forming a memory array can include forming a conductive material in a number of vias and on a substrate structure, the conductive material to serve as a number of conductive lines of the array and coupling the number of conductive lines to the array circuitry.
US08716058B2 Organic light-emitting display device and method of manufacturing the same
An organic light-emitting display device including a substrate; at least one thin-film transistor (TFT) formed on the substrate; a planarizing layer covering the TFT; a pixel electrode, which is formed on the planarizing layer and is connected to the TFT; a protective layer surrounding an edge of the pixel electrode; a pixel defining layer (PDL), which has an overhang (OH) structure protruding more than the top surface of the protective layer, covers the protective layer and the edge of the pixel electrode, and exposes a portion of the pixel electrode surrounded by the protective layer; a counter electrode facing the pixel electrode; and an intermediate layer, which is interposed between the pixel electrode and the counter electrode and includes a light-emitting layer and at least one organic layer, where the thickness of the intermediate layer is greater than the thickness of the protective layer.
US08716053B2 Moisture barrier for photovoltaic cells
A process for sealing a multilayer article against environmental degradation. The article comprises a photoactive layer disposed on a length of flexible substrate and is sealed by applying a sol-gel layer to the outermost layer of the article and curing the sol-gel layer into a flexible, glass protective-coating. The multilayer article can be a photovoltaic device.
US08716052B2 Method for making a structure comprising at least one multi-thick active part
A method for making a structure comprising an active part comprising at least two layers from a first single crystal silicon substrate, said method comprising the steps of: a) making at least one porous silicon zone in the first substrate, b) making an epitaxial growth deposition of a single crystal silicon layer on the entire surface of the first substrate and the surface of the porous silicon zone, c) machining the epitaxially grown single crystal layer at the porous silicon zone to make a first suspended zone, d) removing or oxidizing the porous silicon, e) depositing a sacrificial layer being selective towards silicon, f) machining the first substrate, g) releasing the suspended zones by withdrawing the sacrificial layer.
US08716050B2 Oxide microchannel with controllable diameter
Described herein is a microchannel that is formed beneath and parallel to a surface of a silicon substrate. Silicon migration technology is utilized to form a microchannel that is buried beneath the surface of the silicon substrate. Etching opens at least one end of the microchannel. Oxidization is utilized through the open end of the microchannel to facilitate a controlled diameter of the microchannel.
US08716048B2 Light emitting device and method for manufacturing the same
Disclosed herein is a light emitting device. The light emitting device includes an n-type nitride semiconductor layer; an active layer on the n-type semiconductor layer, an AlN/GaN layer of a super lattice structure formed by alternately growing an AlN layer and a GaN layer on the active layer, and a p-type nitride semiconductor layer on the AlN/GaN layer of the super lattice structure. At least one of the AlN layer and the GaN layer is doped with a p-type dopant. A method for manufacturing the light emitting device is also provided.
US08716047B2 Method for producing transparent conductive layer comprising TIO2 and method for producing semiconductor light-emitting element utilizing said method for producing transparent conductive layer
When a p-layer 4 composed of GaN is maintained at ordinary temperature and TNO is sputtered thereon by an RF magnetron sputtering method, a laminated TNO layer 5 is in an amorphous state. Then, there is included a step of thermally treating the amorphous TNO layer in a reduced-pressure atmosphere where hydrogen gas is substantially absent to thereby crystallize the TNO layer. At the sputtering, an inert gas is passed through together with oxygen gas, and volume % of the oxygen gas contained in the gas passed through is 0.10 to 0.15%. In this regard, oxygen partial pressure is 5×10−3 Pa or lower. The temperature of the thermal treatment is 500° C. for about 1 hour.
US08716045B2 Pulsed growth of catalyst-free growth of GaN nanowires and application in group III nitride semiconductor bulk material
Exemplary embodiments provide semiconductor devices including high-quality (i.e., defect free) group III-N nanowires and uniform group III-N nanowire arrays as well as their scalable processes for manufacturing, where the position, orientation, cross-sectional features, length and the crystallinity of each nanowire can be precisely controlled. A pulsed growth mode can be used to fabricate the disclosed group III-N nanowires and/or nanowire arrays providing a uniform length of about 10 nm to about 1000 microns with constant cross-sectional features including an exemplary diameter of about 10-1000 nm. In addition, high-quality GaN substrate structures can be formed by coalescing the plurality of GaN nanowires and/or nanowire arrays to facilitate the fabrication of visible LEDs and lasers. Furthermore, core-shell nanowire/MQW active structures can be formed by a core-shell growth on the nonpolar sidewalls of each nanowire.
US08716041B2 Method for fabricating side by side light emitting diode (LED) having separate electrical and heat transfer paths
A method for fabricating a light emitting diode includes the steps of providing a thermal conductive substrate having an electrical isolation layer, forming an anode via and a cathode via side by side on a first side of the substrate part way through the substrate, forming an anode through interconnect in the anode via and a cathode through interconnect in the cathode via, thinning the substrate from a second side of the substrate to the anode through interconnect and the cathode through interconnect, and mounting a LED chip to the first side in electrical communication with the cathode through interconnect and the anode through interconnect.
US08716035B2 Nonvolatile memory cell and method of manufacturing the same
Provided are a nonvolatile memory cell and a method of manufacturing the same. The nonvolatile memory cell includes a memory transistor and a driver transistor. The memory transistor includes a semiconductor layer, a buffer layer, an organic ferroelectric layer, and a gate electrode, which are disposed on a substrate. The driver transistor includes the semiconductor layer, the buffer layer, a gate insulating layer, and the gate electrode, which are disposed on the substrate. The memory transistor and the driver transistor are disposed on the same substrate. The nonvolatile memory cell is transparent in a visible light region.
US08716033B2 Oligosaccharide modification and labeling of proteins
The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention.
US08716032B2 Highly sensitive immunochromatography method and kit employing protein hydrolysates
The present invention is to provide an immunochromatography method which is capable of performing a detection with high-sensitivity or reduced false-positives by suppressing the occurrence of false-positive when a signal is amplified. An immunochromatography method includes in a state of where a complex of a test substance and a labeling substance containing a metal coupled with a first binding substance for the test substance is formed, developing the complex on an insoluble carrier in presence of a protease hydrolyzate of protein; capturing the test substance and the labeling substance at a detection site of the insoluble carrier containing a material which has a binding property to the first binding substance for the test substance or a second binding substance for the test substance; and detecting the test substance by amplifying the labeling substance captured.
US08716030B2 Means for the inhibition of anti-β1-adrenergic receptor antibodies
Embodiments of the present invention provide for novel peptides of use for detection and/or inhibition of anti-β1-adrenergic receptor antibodies. Certain embodiments concern uses of cyclic and/or linear peptides. In other embodiments, the present invention relates to novel peptides of use in diagnostic and/or pharmaceutical compositions. Some embodiments concern diagnosing and/or treating cardiac conditions. Cardiac conditions of the instant invention can concern infectious heart disease, non-infectious heart disease, ischemic heart disease, non-ischemic heart disease, inflammatory heart disease, myocarditis, cardiac dilatation, idiopathic cardiomyopathy, idiopathic dilated cardiomyopathy, immune-cardiomyopathy, heart failure, and any cardiac arrhythmia condition.
US08716024B2 Control solution for use in testing an electrochemical system
A method of distinguishing a control solution from a sample in an electrochemical test sensor is performed. The method includes adding a control marker to the control solution. The control solution includes the control marker and analyte. The test sensor includes working and counter electrodes, and a reagent. A potential is applied to the test sensor to oxidize the control marker and the analyte. The resulting electrical current is measured. A potential is applied to the test sensor lower than the other potential in which the potential is sufficient to oxidize the analyte and not the control marker. The resulting electrical current is measured. Determining whether a control solution or a sample is present based on the measured electrical currents. To increase the measured current, a salt may be added to the control solution in an amount sufficient to increase the electrical current by at least 5% as compared to a control solution in the absence of a salt.
US08716023B2 Methods for eliminating or reducing the expression of a genes in a filamentous fungal strains
The present invention relates to methods for reducing or eliminating the expression of a target gene in a filamentous fungal strain, comprising: (a) inserting into the genome of the filamentous fungal strain a double-stranded transcribable nucleic acid construct comprising a first nucleotide sequence comprising a promoter operably linked to a homologous coding region of the target gene and a second nucleotide sequence comprising the homologous coding region, or a portion thereof, of the target gene, wherein the first and second nucleotide sequences are complementary to each other and the second nucleotide sequence is in reverse orientation relative to the first nucleotide sequence; and (b) inducing production of an interfering RNA encoded by the double-stranded transcribable nucleic acid construct by cultivating the filamentous fungal strain under conditions conducive for production of the interfering RNA; wherein the interfering RNA interacts with RNA transcripts of the target gene to reduce or eliminate expression of the target gene. The present invention also relates to the filamentous fungal strains and to methods of producing a biological substance of interest in such filamentous fungal strains.
US08716022B2 Modulation of meiotic recombination
The invention provides methods of modifying the level of expression or functional activity of factors such as enzymes or other catalytic proteins or structural proteins, alone or in concert, to modify the frequency of meiotic homologous recombination involving the exchange of genetic information between non-sister chromatids from homologous maternal and paternal chromosomes. The steps at which modulation may occur include: homologous chromosome pairing, double-strand break formation; resection; strand invasion; branch migration; and resolution. Methods of plant and animal breeding are also provided that utilize the modulation of meiotic homologous recombination.
US08716018B2 Microcarriers for stem cell culture
We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells.
US08716016B2 Immortal avian cell line and methods of use
A avian cell line that supports replication of animal or human viruses, which cell line is adapted to animal-product free growth. The cell line is useful for propagating a virus suitable as a live or a killed vaccine and for virus isolation and diagnostic assays.
US08716009B2 Dispersing feedstocks and processing materials
Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can convert feedstock materials to a sugar solution, which can then be fermented to produce ethanol. Biomass feedstock is dispersed in a liquid medium and then saccharified.
US08716004B2 Gene inactivated mutants with altered protein production
A recombinant filamentous fungal cell (e.g. Aspergillus) having one or more inactivated chromosomal genes is provided. The chromosomal genes in some embodiments correspond to derA, derB, htmA, mnn9, mnn10, ochA, dpp4, dpp5, pepAa, pepAb, pepAc, pepAd, pepF and combinations thereof. The recombinant fungal cells may include further inactivated chromosomal genes which correspond to pepA, pepB, pepC and pepD. The recombinant filamentous fungal cells may include a heterologous nucleic acid encoding a protein of interest. Also provided are methods of producing a protein of interest in said recombinant filamentous fungal cell.
US08715997B2 Variant Hypocrea jecorina CBH2 cellulases
Described herein are variants of H. jecorina CBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability.
US08715994B2 Polypeptides having beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US08715989B2 Glucose dehydrogenase and method for producing the dehydrogenase
A glucose dehydrogenase, having high substrate specificity, can be produced at a low cost, is not affected by oxygen dissolved in a measurement sample and, in particular, has superior thermal stability is obtained by culturing a microorganism belonging to the genus Burkholderia, particularly Burkholderia cepacia. The glucose dehydrogenase produced by the microorganism is collected from the medium and/or from the cells of the microorganism.
US08715986B2 Stereoisomer peptides, ligand-targeted multi- stereoisomer peptide polymer conjugates, and uses thereof
The invention provides compounds of the formula Poly-([SP-LI]n-PL-L2) including a collection of 152 peptides useful to create the compounds, and their uses thereof for the treatment of a variety of mammalian diseases. The compound, a novel ligand-targeted multi-stereoisomer peptide polymer conjugate, comprises two or more stereoisomer peptides and a peptide-ligand conjugated via linkers to a biocompatible hydrophilic polymer, preferably HPMA. The increased stability and solubility of the compound carrying the stereoisomer peptides and a peptide-ligand provide ideal pharmaceutical properties including the delivery by the polymer of the peptides into the target cells. The compounds of the invention are useful therapeutics for the treatment of a variety of mammalian diseases. Examples of such diseases in human patients include abnormal angiogenesis, pathological conditions of the eye, cancer, metastasis, diabetes, Alzheimer's and Parkinson's diseases, brain and neurodegenerative disorders, bipolar disorder, and diseases caused by aging and pathogen agents, to name a few.
US08715980B2 System for cultivation and processing of microorganisms, processing of products therefrom, and processing in drillhole reactors
Described are methods of cultivating autotrophic microorganisms, particularly microalgae or diatoms, in a bioreactor by entraining a culture of the microorganisms in a tenuous, gelated, thixotrophic carrier medium having nutrients therefor and moving the medium along a passage at a sufficiently slow speed to enable laminar flow which in cross section is closed and which has transparent walls through which the culture is irradiated to enable photosynthesis. The method includes effecting convective turnover of the culture and medium as they flow along the passage by differentially heating the medium laterally relative to the flow direction so as to produce a generally helical flow of the culture and medium. Also described are processing methods, both physical and chemical, performed underground e.g. in drillholes, to utilize decavitation energy under ambient elevated pressures, including processes to implement lysis of the micro-organisms, producing methanol, syngas synthesis, Haber ammonia synthesis, Fischer-Tropsch reactions, supercritical reactions, dimethyl ether synthesis, and nitric acid synthesis.
US08715976B2 Recombinant microorganisms having enhanced propanol and method for preparing propanol using the same
The present invention relates to mutant microorganisms having the ability to produce propanol in high concentration and high yield, and to a method of producing propanol using the same. More particularly, the invention relates to mutant microorganisms having the ability to produce propanol in high concentration and high yield, which have introduced therein genes that encodes enzymes which are involved in the biosynthesis of propanol from threonine, and to a method of producing propanol using the same.
US08715969B2 Delignification of biomass with sequential base treatment
A method for the production of a saccharification product is provided, the method comprising: a) providing a cellulosic feedstock comprising lignin; b) contacting, in water, the feedstock of (a) with at least one metal carbonate at time 0 hour under suitable initial reaction conditions to produce a first delignification slurry; c) contacting the first delignification slurry with a nucleophilic base at time (0+n) hour, where n represents a number greater than zero, under suitable secondary reaction conditions to form a second delignification slurry comprising a lignin-containing liquid fraction and a polysaccharide-enriched solid fraction; d) separating the lignin-containing liquid fraction from the polysaccharide-enriched solid fraction; and e) contacting at least a portion of the polysaccharide-enriched solid fraction with an enzyme consortium to produce a saccharification product comprising xylose and glucose monomers wherein the overall yield of xylose and glucose monomers in the saccharification product are individually at least about 50%.
US08715967B2 Method for accurately counting starting molecules
Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications.
US08715965B2 Method of amplifying nucleic acid from blood
A method of amplifying nucleic acid from blood, the method including performing an electrodialysis on a blood sample to reduce the ionic strength of the sample, and performing a Polymerase Chain Reaction (“PCR”) using the blood sample on which the electrodialysis is performed as a template.
US08715964B2 Expression of IL-12 family heterodimers
The present invention provides methods of improving the levels and stability of expression of interleukin-12 family cytokine polypeptides by expressing the alpha and beta subunits of the polypeptides at their determined relative molar ratios that increase the levels and stability of expression of the heterodimer, e.g., in comparison to heterodimer expressed at an equimolar ratio.
US08715961B2 Methods of obtaining a specific binding member that binds eotaxin
Specific binding members directed to eotaxin-1, in particular human antibodies and antibody fragments against human eotaxin-1 and especially those which neutralize eotaxin-1 activity. The antibodies VH and/or VL domain of the scFv fragment herein termed CAT-212 and of the IgG4 antibody herein termed CAT 213. One or more complementary determining regions (CDRs) of the CAT-212-213 VH and/or VL domains, especially VH CRD3 in other antibody framework regions. Compositions containing specific binding members, and their use in methods of inhibiting or neutralizing eotaxin, including methods of treatment of the human or animal body by therapy.
US08715960B2 Aberrant mitochondrial DNA, associated fusion transcripts and translation products and hybridization probes therefor
The present invention provides novel mitochondrial fusion transcripts, the parent mutated mtDNA molecules, and the resulting translation products (proteins) for predicting, diagnosing and/or monitoring cancer. Hybridization probes complementary thereto for use in the methods of the invention are also provided.
US08715957B2 Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
The invention provides non-naturally occurring microbial organisms having a toluene, benzene, p-toluate, terephthalate, (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate, (2-hydroxy-4-oxobutoxy)phosphonate, benzoate, styrene, 2,4-pentadienoate, 3-butene-1ol or 1,3-butadiene pathway. The invention additionally provides methods of using such organisms to produce toluene, benzene, p-toluate, terephthalate, (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate, (2-hydroxy-4-oxobutoxy)phosphonate, benzoate, styrene, 2,4-pentadienoate, 3-butene-1ol or 1,3-butadiene.
US08715955B2 Laser microdissection apparatus and method
Systems and methods for automated laser microdissection are disclosed. In one variation, targeted biological material is manually or automatically selected and a transfer film is placed in juxtaposition to the location of an interior of a cut path. In another variation, a sample of biological material is mounted onto a polymer membrane which is then placed onto a substrate. Targeted biological material is manually or automatically selected and a transfer film is placed in juxtaposition with the targeted biological material on the side of the biological material. In yet another variation, a sample of biological material is mounted onto a polymer membrane which is then inverted onto a substrate. Targeted biological material is manually or automatically selected and a transfer film is placed in juxtaposition with the targeted biological material on the side of the polymer membrane. Then, an UV laser cuts along a cut path around the targeted portions of biological material in a closed cut path or a substantially closed cut path defining an interior and an exterior portion of the tissue sample. In a substantially closed cut path, bridges are left spanning the interior of the cut path and the exterior of the cut path. An IR laser activates at least a portion of the transfer film such that the transfer film in the vicinity of targeted portion adheres to the biological material interior to the cut path. The transfer film is then removed separating the targeted portions of biological material which are adhered to the transfer film from the remaining portion of the tissue sample.
US08715947B2 Inhibition of the interaction between 5T4 oncofoetal glycoproteins and CXC chemokine receptors as a method of identifying chemotaxis inhibitors
Methods and agents are disclosed based on the finding that 5T4 interacts with CXCR4 in the cell membrane to form a complex, and that the 5T4 transmembrane region is involved in the promotion of CXCR4 membrane expression and chemotactic response.
US08715946B2 Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds. Also, the invention relates to the discovery of specific hT2R9 alleles and their disparate activity in functional assays with the same bitter ligands. The invention further relates to the use of these T2R receptors in assays for identifying ligands that modulate the activation of these taste receptors by specific bitter ligands and related compounds. These compounds may be used as additives and/or removed from foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste. Also T2R ligands may be used as therapeutics to treat and modulate T2R associated gastrointestinal and metabolic functions as well as treat gastrointestinal and metabolic diseases such as eating disorders, food sensing, food absorption, obesity, diabetes, Crohn's disease, celiac disease, et al.
US08715940B2 Method of making recombinant influenza virus
The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses, entirely from cloned cDNAs and in the absence of helper virus.
US08715938B2 Reversible di-nucleotide terminator sequencing
The present teachings provide methods, compositions, and kits for synthesizing and sequencing nucleic acids. In some embodiments, reversible di-nucleotide compounds are employed along with cleaving reactions that remove a label and a blocking moiety. Improved sequencing efficiency is achieved by the rapid polymerase-mediated incorporation of reversible di-nucleotide compounds. In some embodiments, the di-nucleotides do not contain conventional nucleotide triphosphates, but rather employ amino acid phosphoramidate nucleotides (AAPNs).
US08715930B2 Loading molecules onto substrates
Disclosed are compositions, devices, and methods for loading molecules of interest onto a substrate by contacting beads having molecules of interest attached to them with the substrate, for example by providing a field that brings the beads into proximity or contact with the substrate and moves the beads with respect to the substrate. Such molecules of interest can be deposited onto substrates for single-molecule analysis.
US08715922B2 Virus causing respiratory tract illness in susceptible mammals
The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
US08715921B2 Method of diagnosing apoplectic stroke/asymptomatic brain infarction using acrolein content
The present invention provides a diagnostic method for stroke/asymptomatic cerebral infarction and a screening method for patients with stroke/asymptomatic cerebral infarction, which comprise measuring acrolein content or polyamine content; or polyamine oxidase activity or protein content of polyamine oxidase in plasma. The knowledge of the present invention indicates the possibility of preventing, inhibiting the progression of stroke/asymptomatic cerebral infarction by inhibiting polyamine oxidase, and the possibility of obtaining a therapeutic agent for stroke/asymptomatic cerebral infarction by searching for compounds that inhibit polyamine oxidase.
US08715920B2 Composition for preserving platelets during photosensitization
A platelet preservation composition is disclosed. The composition comprises a photosensitizer, an inhibitor of platelet activation, and/or an anticoagulant. The preservation composition allows inactivation of pathogens in a platelet preparation while maintaining the functionality of the platelets.
US08715916B2 Pattern forming method and resist underlayer film-forming composition
A pattern-forming method includes forming a resist underlayer film on a substrate using a resist underlayer film-forming composition. The resist underlayer film-forming composition includes a base component, and a crosslinking agent. The crosslinking agent has a partial structure represented by a following general formula (i). X represents an oxygen atom, a sulfur atom, or —NR—. R represents a hydrogen atom, an alkyl group having 1 to 9 carbon atoms, or an aryl group having 6 to 30 carbon atoms. n1 is an integer from 1 to 6. R1 represents a hydrogen atom, an alkyl group having 1 to 9 carbon atoms, or an aryl group having 6 to 30 carbon atoms.
US08715914B2 Organometallic composition for forming a metal alloy pattern and a method of forming such a pattern using the composition
An organometallic composition containing an organometallic compound (I) containing Ag, an organometallic compound (II) containing Au, Pd, or Ru, and an organometallic compound (III) containing Ti, Ta, Cr, Mo, Ru, Ni, Pd, Cu, Au, or Al, wherein the metal components of organometallic compounds (II) and (III), respectively, are present in an amount of 0.01˜10 mol % based on the amount of Ag in the organometallic compound (I), and a method of forming a metal alloy pattern using the same. Silver alloy patterns can be obtained through a simplified manufacturing process, which patterns have enhanced heat resistance, adhesiveness, and chemical stability. The method may be applied to making a reflective film for LCD and metal wiring (gate, source, drain electrode) for flexible displays or flat panel displays, and further to CMP-free damascene processing and PR-free ITO film deposition.
US08715904B2 Photocurable composition
A low surface energy photoresist composition is described that comprises a silicone-polyether block copolymer, wherein the silicone block comprises 35 wt. % or more of said copolymer. When compounded with a photoresist composition, the composition enables the release of a phototool from the photoresist layer.
US08715899B2 Carrier for two-component developer, two-component developer, image forming method, and image forming apparatus
A carrier for a two-component developer includes magnetic particles, and a resin coating layer that covers the magnetic particles. The resin coating layer contains metal boride particles having a volume average primary particle diameter of from about 300 nm to about 2,500 nm.
US08715898B2 Electrostatic charge image developer, process cartridge, image forming apparatus, and image forming method
An electrostatic charge image developer includes a toner for developing an electrostatic charge image, containing toner particles including a polyester resin having a rosin skeleton and an external additive, and a carrier having core material particles and a coating resin layer which coats the surface of the core material particles, in which the hardness of the coating resin layer is from 1.2 times to 2.0 times that of the toner particles.
US08715894B2 Integrated color mask
The invention relates to a process for forming a structure comprising providing a support, coating one side of said support with a colored mask, coating a layer photopatternable by visible light, and exposing the layer through the colored mask with visible light to photopattern the layer.
US08715891B2 Mask and pattern forming method
According to one embodiment, a mask used with an exposure apparatus is disclosed. The mask includes a main pattern, and a sub-pattern having a dimension smaller than a resolution limit of the exposure apparatus. The sub-pattern is arranged next to the main pattern. The sub-pattern includes a first sub-pattern arranged next to the main pattern, and second sub-patterns contacting the first sub-pattern and arranged along a longitudinal direction of the first sub-pattern. The sub-patterns satisfy a condition of P≦λ/(NA(1+σ0)). Where P is a pitch of the second sub-patterns, NA is a numerical aperture of the exposure apparatus, λ and σ0 are respectively exposure wave length and maximum σ when the main pattern by using the exposure apparatus.
US08715885B2 Fuel cell and a method of manufacturing a fuel cell
A solid oxide fuel cell comprises a porous anode electrode, a dense non-porous electrolyte and a porous cathode electrode. The anode electrode comprises a first member and a plurality of parallel plate members extending from the first member. The cathode electrode comprises a second member and a plurality of parallel plate members extending from the second member. The plate members of the cathode electrode inter-digitate with the plate members of the anode electrode and the electrolyte fills the spaces between the first and second members and the parallel plate members of the anode electrode and the cathode electrode.
US08715884B2 Fuel cell and process for manufacturing a fuel cell
The present invention pertains to a fuel cell with a storage unit (4) for storing hydrogen (Hx), with a proton conductive layer, which covers a surface of the storage unit (4), and with a cathode (7) on a side of the proton conductive layer, which side is located opposite, wherein the storage unit (4) is directly coupled with an anode and/or the storage unit (4) is incorporated in a substrate (1) of a semiconductor. The storage unit (4) is preferably connected to the substrate (1) at least via a stress compensation layer (3).
US08715882B2 High power density fuel cell comprising an array of microchannels
A phosphoric acid fuel cell according to one embodiment includes an array of microchannels defined by a porous electrolyte support structure extending between bottom and upper support layers, the microchannels including fuel and oxidant microchannels; fuel electrodes formed along some of the microchannels; and air electrodes formed along other of the microchannels. A method of making a phosphoric acid fuel cell according to one embodiment includes etching an array of microchannels in a substrate, thereby forming walls between the microchannels; processing the walls to make the walls porous, thereby forming a porous electrolyte support structure; forming anode electrodes along some of the walls; forming cathode electrodes along other of the walls; and filling the porous electrolyte support structure with a phosphoric acid electrolyte. Additional embodiments are also disclosed.
US08715881B2 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the same, electrolyte membrane for fuel cell including the same, and fuel cell using the same
A benzoxazine-based monomer, a polymer thereof, an electrode for a fuel cell including the same, an electrolyte membrane for a fuel cell including the same, and a fuel cell using the same. The aromatic ring may contain up to 2 nitrogens within the ring. Single ring and fused ring substituents are attached to the pendent nitrogen. The ring substituents may be heterocyclic.
US08715878B2 Polymer electrolyte fuel cell, membrane electrode assembly and manufacturing method thereof
The present invention provides a method for manufacturing an MEA with high production efficiency. It is a feature of the present invention that the method for manufacturing an MEA includes coating a first catalyst ink on a substrate to form a coated layer of the first catalyst ink, removing the solvent in the coated layer of the first catalyst ink to form a first electrode catalyst layer, coating an electrolyte ink on the first electrode catalyst layer to form a coated layer of the electrolyte ink, removing the solvent in the coated layer of the electrolyte ink to form a polymer electrolyte membrane, coating a second catalyst ink on the polymer electrolyte membrane to form a coated layer of the second catalyst ink, and removing the solvent in the coated layer of the second catalyst ink to form a second electrode catalyst layer.
US08715876B2 Fuel cell vehicle
A fuel cell vehicle is provided. At the time of regeneration of electric power by a motor, an ECU places a DC/DC converter in a direct connection state under control, and stores electric power in a battery while decreasing oxygen concentration or hydrogen concentration by a gas supply unit to decrease electric power generated by a fuel cell.
US08715869B2 Fuel cell, method for operating fuel cell and fuel cell system
A fuel cell, a method for operating a fuel cell and a fuel cell system, which ensure no dew condensation for a wet reaction gas in the inlet area of gas channels in plates in a fuel cell stack, are provided. Gas channels 2 and heat medium channels are disposed on one surface and the other surface of one plate 1, respectively. Gas channels are disposed on the other plate such that they face the gas channels 2 in the plate 1. A gas inlet header 3 is disposed at the upper part of the gas channel 2 in the plate 1 and a heat medium inlet header is disposed at the upper part of the heat medium channels such that they face the gas inlet header on the other side. Cooling water such as heat medium is supplied from the heat medium supply manifold hole 7 to the heat medium inlet header, thereby warming up the same. The water vapor in the reaction gas (wet fuel gas) is prevented from being condensed in the inlet area of the gas channels 2 by heating up the gas inlet header by the heat conduction.
US08715861B2 Bipolar second battery with terminal plate including current suppressing device, battery pack and vehicle equipped with the same
A bipolar secondary battery is provided with an electric power generating unit, a pair of terminal plates. The electric power generating unit includes a plurality of bipolar electrodes stacked on one another with an electrolyte layer disposed between the bipolar electrodes and separating the bipolar electrodes. Each of the bipolar electrodes includes a collector with a positive electrode active material layer formed on a first side surface of the collector, and a negative electrode active material layer formed on a second side surface of the collector. The first terminal plate is connected to a first stacking direction facing end of the electric power generating unit. The second terminal plate is connected to a second stacking direction facing end of the electric power generating unit. At least one of the terminal plates includes an electric current suppressing device that suppresses an electric current occurring when an internal short circuit occurs in the electric power generating unit.
US08715858B2 Method for preparing lithium manganese oxide positive active material for lithium ion secondary battery, positive active material prepared thereby, and lithium ion secondary battery including the same
A method for preparing a lithium manganese oxide positive active material for a lithium ion secondary battery, which has spherical spinel-type lithium manganese oxide particles having two or more different types of sizes, the method including uniformly mixing manganese oxide having two or more different types of sizes with a lithium containing compound, and heat treating the resultant mixture to obtain lithium manganese oxide.
US08715855B2 Method of producing lithium ion-storing/releasing material, lithium ion-storing/releasing material, and electrode structure and energy storage device using the material
A method of producing a material capable of electrochemically storing and releasing a large amount of lithium ions is provided. The material is used as an electrode material for a negative electrode, and includes silicon or tin primary particles composed of crystal particles each having a specific diameter and an amorphous surface layer formed of at least a metal oxide, having a specific thickness. Gibbs free energy when the metal oxide is produced by oxidation of a metal is smaller than Gibbs free energy when silicon or tin is oxidized, and the metal oxide has higher thermodynamic stability than silicon oxide or tin oxide. The method of producing the electrode material includes reacting silicon or tin with a metal oxide, reacting a silicon oxide or a tin oxide with a metal, or reacting a silicon compound or a tin compound with a metal compound to react with each other.
US08715851B2 Battery pack and battery pack stack
A battery pack includes battery cells, each including a first conductive terminal and a second conductive terminal, the battery cells being arrayed from a first side to a second side of the battery pack. A first conductive tab electrically connects the first conductive terminals of the battery cells to each other, a second conductive tab electrically connects the second conductive terminals of the battery cells to each other, a first conductive external terminal is electrically connected to a side of the first conductive tab and is configured to be electrically connected to an external device, and a second conductive external terminal is electrically connected to a side of the second conductive tab and is configured to be electrically connected to the external device.
US08715850B2 Battery module and method of manufacturing the same
A battery module 8 containing parallel blocks 9 connected to a protection circuit via a lead plate 2, wherein the parallel blocks 9 are welded to both sides of the lead plate without bending the lead plate 2 into a U shape. Thus it is possible to reduce the length of the lead plate 2 and suppress a voltage drop on the lead plate 2. Further, since the lead plate 2 is not bent into a U shape, the assembling accuracy of the battery module is improved and the battery module is easily packaged with a small size.
US08715848B2 Lithium ion secondary battery with insulating member having a broken hollow portion and method for producing the same
An electrode assembly (30) is formed by combining a positive electrode plate (14), a separator (15), and a negative electrode plate (18), and the electrode assembly (30) was wound. An insulating member (21) having a hollow portion (22) is placed on the positive electrode plate (14), the negative electrode plate (18), or the separator (15) before the end of the winding step so that the insulating member (21) is incorporated inside the outermost of the electrode assembly (30) and into a corner portion (31) of the electrode assembly (30) in the winding direction. After a winding end portion (32) of the electrode assembly (30) is fixed, the hollow portion (22) is broken. Thereby, a space (20) resulting from the hollow portion (22) is formed inside the outermost of the electrode assembly (30).
US08715844B2 Electronic apparatus
An electronic apparatus which uses a battery as a power source includes a battery storage unit configured to store the battery which can be inserted and removed, a locking member configured to move between a position at which the battery stored in the battery storage unit is locked and a position at which the lock of the battery is released by rotating in a direction perpendicular to a direction that the battery is inserted to and removed from the battery storage unit, a drive member which is movably supported in the insertion and removal direction of the battery with respect to the battery storage unit, and on which a claw abutting on the locking member is formed, and an urging member configured to urge the drive member in a direction that the battery is ejected, to attach the claw to the locking member.
US08715842B2 Battery pack
A battery pack that includes a bare cell, a protection circuit module arranged on the bare cell and a case arranged on the protection circuit module, wherein the protection circuit module and the case include coupling members to couple the protection circuit module to the case.
US08715830B2 Electrically conducting member, process cartridge, and electrophotographic apparatus
To provide an electrically conducting member for electrophotography which can not easily come to change in electrical resistance value even upon application of direct current and also has made any ion conducting agent kept from bleeding. The electrically conducting member has an electrically conducting substrate and an electrically conducting layer; the electrically conducting layer containing an epichlorohydrin rubber having in the molecular structure at least an alkylene oxide (AO) unit, an epichlorohydrin (ECH) unit and a unit having a sulfonate ion; the AO unit being at least one unit of an ethylene oxide unit, a propylene oxide unit and a butylene oxide unit; and the AO unit(s) in the rubber being in a content of 5 to 60% by mass in total and the ECH unit in the rubber being in a content of 30% by mass or more.
US08715829B2 Glass plate for display devices
To provide a glass plate for display devices wherein without carrying out a post treatment, the depth of a compression stress layer is increased, while the surface compression stress is prevented from being excess only by chemical tempering. A glass plate for display devices, which is obtained by chemically tempering a glass plate comprising, as represented by mol % based on the following oxides, from 50 to 74% of SiO2, from 1 to 10% of Al2O3, from 6 to 14% of Na2O, from 3 to 15% of K2O, from 2 to 15% of MgO, from 0 to 10% of CaO and from 0 to 5% of ZrO2, wherein the total content of SiO2 and Al2O3 is at most 75%, the total content of Na2O and K2O, i.e. Na2O+K2O, is from 12 to 25%, and the total content of MgO and CaO, i.e. MgO+CaO, is from 7 to 15%.
US08715828B2 Emulsion of metallized particles comprising a compound having a pendant Si-H group
A particle is formed from a dispersion and includes a compound and a metal disposed on the particle. The compound has the chemical formula R—Si—H. In this formula, R is an organic or inorganic moiety. The particle is also included in a corresponding dispersion. The particle is formed from a method that includes the step of forming the dispersion. The method also includes the step of disposing the metal on the particle.
US08715823B2 Piezoelectric thin film, method of manufacturing piezoelectric thin film, piezoelectric element, and ink jet recording head
There are disclosed a piezoelectric thin film having less non-uniform portions and holding satisfactory piezoelectric characteristics, a method of manufacturing the film, a piezoelectric element using the piezoelectric thin film, and an ink jet system recording head using the piezoelectric element. In the piezoelectric thin film of perovskite crystals formed on a substrate by a sol-gel process and represented by a general formula Pb(1-x)Lax(ZryTi1-y)O3 (where 0≦x<1, 0.05≦y≦1), a film thickness of the thin film is 1000 nm or more and 4000 nm or less, and a difference between a maximum value and a minimum value of y in an arbitrary portion of the thin film is 0.05 or less.
US08715816B2 Multilayer film and method for manufacturing same
A multilayered film is shown and described that is used in particular for packaging, which comprises at least one first layer A and at least one second layer B, wherein layer A contains thermoplastic polyester and layer B contains thermoplastic starch. The multilayered film according to the invention is characterized by excellent barrier properties, low sensitivity to moisture, and good mechanical strength.
US08715814B2 Liquid chemical deposition apparatus and process and products therefrom
A method, apparatus and material produced thereby in an amorphous or crystalline form having multiple elements with a uniform molecular distribution of elements at the molecular level.
US08715812B2 Metallic luster printed medium and method of preparing same
A printed medium having a metallic luster includes an ink-receiving layer on a substrate and a layer of metal oxide particles disposed on the ink-receiving layer. A portion of the ink-receiving layer corresponding to at least one feature includes a non-particulate, light-absorbing colorant dispersed in the ink-receiving layer. An amount of the non-particulate, light-absorbing colorant in the ink-receiving layer portion is sufficient to render a predetermined hue to the metallic luster of the at least one feature. The metal oxide particles have an average diameter of about 3 nm to about 300 nm. The ink-receiving layer has pores that are smaller than the average diameter of the metal oxide particles.
US08715804B2 Method and device for high density data storage
The present invention is directed to a method for producing a data storage medium on a surface of a substrate for storing data in the form of topographic features. The method comprises a first step wherein a crosslinking agent containing at least three alkyne groups is deposited on the surface of the substrate. In a second step the deposited cross linking agent is cured so as to obtain the data storage medium in the form of a crosslinked polymeric layer on the surface of the substrate. The invention is further directed to a data storage medium obtained by this method and a data storage device comprising this data storage medium.
US08715803B2 Ceramic welds, and a method for producing the same
A method of producing a ceramic weld, including identifying a ceramic first surface and a ceramic second surface to be bonded together, maintaining a non-oxidizing atmosphere over the first and second surfaces, and engaging the first and second surfaces to define a joint. An arc is generated between an electrode and the joint to create a liquid phase, and the liquid phase is cooled to yield a solid fusion layer, wherein the first and second surfaces are joined in the fusion layer.
US08715797B2 Adhesive composition for a debondable self-adhesive label
Hot-melt pressure-sensitive adhesive (HMPSA) composition is disclosed comprising: a) 25 to 50% of a blend of SBS and SB styrene block copolymers; b) 45 to 75% of compatible tackifying resins having a softening temperature of between 80 to 150° C.; and c) 0.5 to 5.5% of fatty acids, the hydrocarbon chain of which comprises 10 to 22 carbon atoms. Also disclosed are a multilayer system comprising an HMPSA layer, a printable support layer and an adjacent protective layer. A self-adhesive label and process for recycling a labeled article with debonding of said label by immersing the article in a hot basic aqueous solution are also disclosed.
US08715794B2 Recording medium
A recording medium includes a base paper, a polymer layer disposed on the base paper, and an ink-receiving layer disposed on the polymer layer. The base paper has a thickness of 50 μm or more and 130 μm or less. The polymer layer has a thickness of 20 μm or more and 60 μm or less. The polymer layer has an arithmetic average surface roughness Ra1 of 0.12 μm or more and 0.18 μm or less. The polymer layer has a roughness curve element average length RSm of 0.01 mm or more and 0.20 mm or less. The recording medium has an arithmetic average surface roughness Ra2 of 0.13 μm or less.
US08715793B2 Conductive laminate and touch panel using same
A touch panel that not only demonstrates little deterioration of performance even in harsh environments at high temperature and high humidity, but is also free of the occurrence of a whitening phenomenon occurring during sudden changes in temperature and humidity, while also having superior shock resistance. A conductive laminate in which a uniform or arbitrarily patterned conductive layer containing a polythiophene-based conductive agent and an adhesive layer containing an acidic component are in direct contact over the entire surface or a portion thereof, and a touch panel in which it is used.
US08715792B2 Liquid-crystal display device and liquid-crystal cell
A liquid-crystal display device comprising first and second polarizing elements, and a liquid-crystal cell disposed between the first and second polarizing elements, wherein the liquid-crystal cell comprises first and second substrates (provided that the first substrate is disposed closer to the first polarizing element, and the second substrate is disposed closer to the second polarizing element), a liquid-crystal layer disposed between the first and second substrates, a color filter layer disposed on an inner surface of the first substrate, and an in-cell polarizing layer disposed between the color filter layer and the liquid-crystal layer, the absorption axis of the first polarizing element and the absorption axis of the in-cell polarizing layer are parallel to each other, and the sum total of the absolute values of Re of all the layers disposed between the in-cell polarizing layer and the first polarizing element is equal to or less than 10 nm, and the sum total of the absolute values of Rth thereof is equal to or less than 15 nm.
US08715789B2 Chemical vapor deposition for an interior of a hollow article with high aspect ratio
A method and apparatus for plasma enhanced chemical vapor deposition to an interior region of a hollow, tubular, high aspect ratio workpiece are disclosed. A plurality of anodes are disposed in axially spaced apart arrangement, to the interior of the workpiece. A process gas is introduced into the region. A respective individualized DC or pulsed DC bias is applied to each of the anodes. The bias excites the process gas into a plasma. The workpiece is biased in a hollow cathode arrangement. Pressure is controlled in the interior region to maintain the plasma. An elongated support tube arranges the anodes, and receives a process gas tube. A current splitter provides a respective selected proportion of a total current to each anode. One or more notch diffusers or chamber diffusers may diffuse the process gas or a plasma moderating gas. Plasma impedance and distribution may be controlled using various means.
US08715788B1 Method to improve mechanical strength of low-K dielectric film using modulated UV exposure
Methods and apparatus for improving mechanical properties of a dielectric film on a substrate are provided. In some embodiments, the dielectric film is a carbon-doped oxide (CDO). The methods involve the use of modulated ultraviolet radiation to increase the mechanical strength while limiting shrinkage and limiting any increases in the dielectric constant of the film. Methods improve film hardness, modulus and cohesive strength, which provide better integration capability and improved performance in the subsequent device fabrication procedures such as chemical mechanical polishing (CMP) and packaging.
US08715783B2 Porous ABPBI [poly (2, 5-benzimidazole)] membrane and process of preparing the same
The present invention relates to a porous ABPBI (phosphoric acid doped poly(2,5-benzimidazole)) membrane and process of preparing the same. A stable porous ABPBI (Phosphoric Acid Doped Poly(2,5-benzimidazole)) membrane stable to acids, bases, solvents and autoclaving is disclosed. The membrane finds use for separation of solutes in solution in acids, bases and solvents.
US08715778B2 Ballast and process for the production of ballast
The present invention relates to ballast which have a high stability and a long service life and to a process for the production of ballast. These ballast are suitable for railway track laying and road construction and dike systems used for example in costal protection. These ballast comprise ballast stones and polyurethane foams based on a reaction mixture of selected polyisocyanates and selected compounds with isocyanate-reactive groups.
US08715777B2 Method for producing glass substrate for magnetic disk and method for producing magnetic disk
In a method in which a cut line is formed on one surface of a planar glass material, and the cut line is allowed to extend in the thickness direction of the glass material, thereby cutting a glass substrate from the glass material, the cut line is selectively formed on a surface having relatively small surface waviness out of two opposing surfaces of the glass material. In the case of a glass material formed into a planar shape on a molten metal, the surface which has come into contact with the molten metal is selected as the surface having relatively small surface waviness. When a disk-shaped glass substrate is cut from the glass material, cutting is performed under conditions where either one of the thickness and the radius of the glass material and the maximum height of surface waviness of the glass material satisfy a predetermined relationship.
US08715776B2 Method for providing AFM exchange pinning fields in multiple directions on same substrate
Simultaneous setting of exchange pinning field magnetization in more than one direction for several thin film structures on a single substrate has been achieved by first orienting the structures as needed. A layer of hard magnetic material is then deposited, suitably patterned to control the direction of its flux, and then magnetized through a single exposure to a strong magnetic field. The assemblage is then thermally annealed (in the absence of any applied field) at a temperature higher than the AFM material blocking temperature, following which the thin film structures are magnetically pinned in the intended directions.
US08715774B2 Liquid droplet ejection method
A liquid droplet ejection method comprises: ejecting a liquid droplet of a functional liquids onto a substrate while scanning relatively the substrate and an ejection head. A plurality of kinds of functional liquids have different drying rates and are ejected onto respective different positions in respective scanning directions during the same scanning operation. Scanning regions of the plurality of kinds of the functional liquids at least partly are overlapped each other.
US08715773B2 Method of making a filter
A method of making a filter adjusts the bottom heights of the color-resisting colors to make the top ends of the color-resisting blocks be in a same level by disposing the foundation layer between the transparent substrate and the light-shielding layer and disposing the groove in the foundation layer, so that ensuring that surfaces of the filter have a good evenness and the alignment of liquid crystals is normal for enhancing the displaying effect of the liquid crystal display. The present invention improves the bottom evenness of the through holes by disposing the foundation layer on the bottoms of the through holes, thereby eliminating the “ox horn-shaped segment difference” of the protruding edges of the color-resisting blocks formed later.
US08715772B2 Thermal deposition coating method
A process for the thermal deposition coating of a workpiece is provided that comprises the steps of: thermally depositing a coating on a metallic surface of a workpiece from a deposition head wherein at least one condition selected from the group of: coating deposition rate onto said surface, relative motion between the surface and said deposition head, and cryogenic coolant application rate onto said workpiece is controllable; substantially simultaneously measuring temperatures at a plurality of locations over the metallic surface of the workpiece; determining an average temperature of the temperatures measured in step (b); comparing the average temperature to a preselected minimum temperature and a preselected maximum temperature for the workpiece; and adjusting at least one of the controllable conditions if said average temperature is not between the preselected minimum temperature and the preselected maximum temperature for the workpiece.
US08715766B2 Process for producing high flavour cocoa
The disclosure is directed to a process for the manufacture of roasted cocoa nibs. It is further directed to processes of producing cocoa liquor and cocoa powder from the roasted cocoa nibs.
US08715763B2 Fruit and vegetable films and uses thereof
The present invention is directed to monolayer, bilayer, and multilayer films made from fruit, vegetable or a combination thereof, which films have the thinness, strength, flexibility, and crispness to serve as alternates or substitutes for seaweed-based films such as nori, while providing the nutrition and flavor of fruits and vegetables. The films are useful for wrapping around a multiplicity of foods, and can be used to provide wrapped foods, including for example fruit and vegetable wrapped sushi and onigiri.
US08715761B2 Flavor molecules
A method of providing a range of flavors to an orally-receivable or ingestible product, the method including adding at least one compound, including salts thereof, of the formula: wherein R1 may be H, OH, O(CH2)2OH, OCH2OCH3 or R2 may be selected from a range of 5- and 6-membered heterocyclic rings, and wherein R3 may be H or OH. The compounds give rise to a wide range of flavors, and some are useful as sweetness enhancers, this allowing sweetener content to be reduced while maintaining sweetness. Also disclosed are orally-receivable or ingestible products including the compounds.
US08715759B2 Method and apparatus for antimicrobial treatment of meat trimmings for subsequent grinding
An antimicrobial intervention for the production of ground meats by treating the exterior of the meat trimmings with an antimicrobial agent before grinding. An apparatus for applying an antibacterial agent to meat trimmings includes a closed or essentially closed chamber for limiting the escape of the antimicrobial agent to the environment during antimicrobial treatment of the trimmings, an entrance system for introducing trimmings into the closed chamber while preventing or significantly limiting the antimicrobial agent from escaping into the environment, an application system for applying an effective amount of the antimicrobial agent to exposed surfaces of the trimmings in the closed chamber; and an exit system for removing the treated trimmings from the closed container while preventing or significantly limiting the escape of antimicrobial agent into the environment.
US08715753B1 Formulation for eliminating bedbugs
A formulation for eliminating bedbugs containing mustard powder and water and optionally flour or a starch such as cornstarch. The ratio of mustard powder to water may be about 2 grams mustard powder to about 10 mL water. The ratio of flour to water is about 3 grams flour to about 10 mL water.
US08715750B2 Vegetable extract and method of use as an active principle in the production of a pharmacologically active product for the treatment of tissue lesions, and method for obtaining the extract
A resin extract from the Ficus pertusa L.f and/or Ficus eximia Schott tree and method of use as an active principle in the production of a pharmacologically active product for the treatment of acute and/or chronic tissue lesions in both bone tissue and soft tissue. A method for obtaining the extract is also disclosed.
US08715749B2 Products containing polyphenol(s) and L-arginine
Foods and pharmaceuticals which contain cocoa and/or nut procyanidin(s) in combination with L-arginine are effective to induce a physiological increase in nitric oxide production in a mammal having ingested the product. A preferred food product is a confection, particularly a dark or milk chocolate containing nuts. The procyanidins may be natural or synthetic and may be provided by food ingredients such as chocolate liquor and/or cocoa solids prepared from underfermented beans and nut skins. The L-arginine may be natural or synthetic and may be provided by food ingredients such as nut meats, nut pastes, and/or nut flours, seeds, seed pastes, and/or seed flours, or gelatin. The beneficial health effects may include, for example, reduced blood pressure, resistance to cardiovascular disease, and anticancer activity.
US08715744B2 Inorganic resorbable bone substitute material
The invention relates in particular to a hydroxyl apatite/silica granular material of defined morphology, a highly porous bone substitute material based on this granular material and a glass ceramic material based in turn thereon as bone substitute material which is characterized by a variable mechanical strength, and shaped bodies of this material, materials of different mechanical strength being preferably used in the shaped body. The bone substitute materials according to the invention are characterized by a high resorbability in vivo.
US08715743B2 Human monoclonal antibodies and methods for producing the same
The present invention provides for methods of producing human monoclonal antibodies against a wide variety of antigens including bacterial and viral antigens, as well as tumor antigens, and various autoantigens. Also provided are the antibodies themselves, nucleic acids encoding such antibodies, cells producing such antibodies, and methods of using such antibodies for diagnostic assays and passive immunity against disease states such as infection and cancer.
US08715741B2 Water-dispersible oral, parenteral, and topical formulations for poorly water soluble drugs using smart polymeric nanoparticles
Polymeric nanoparticles with a hydrophobic core and a hydrophilic shell are formed from: 1) N-isopropylacrylamide (NIPAAM), at a molar ratio of about 50% to about 90%, and preferably 60% for specific delivery routes such as oral or parenteral; either water-soluble vinyl derivatives like vinylpryolidone (VP) or vinyl acetate (VA), or water insoluble vinyl derivatives like methyl methacrylate (MMA) or styrene (ST), at a molar ratio of about 10% to about 30%; and acrylic acid (AA), at a molar ration of about 10% to about 30%.
US08715737B2 Method to make porous materials and their applications
The present invention relates a method to make porous materials which are useful in pharmaceutical, medicine, industry, and agriculture. The most advantage of the porous materials is to provide extremely large surface area for further modification and to incorporate a bioactive reagent in a mild condition to make the porous materials bioactive, biocompatible and biodegradable.
US08715733B2 Enhanced adipose tissue
An enhanced adipose tissue containing native adipose tissue and a concentrated amount of an active agent derived from adipose tissue, wherein the enhanced adipose tissue is preferably injected into the intervertebral disc of a patient suffering from degenerative disc disease.
US08715731B2 Process of reducing the bitter taste of water soluble actives by co-grinding the active with β cyclodextrin
A process for reducing the intensity of the intrinsic bitter taste of a water soluble active which comprises dry mixing of said active with β-cyclodextrin.
US08715723B2 Compositions and methods for delivery of amino-functional drugs
Described are flexible, finite systems for the transdermal administration of scopolamine, comprising: (a) a polymer matrix comprising a polymer blend comprising (i) a non-functional acrylic-based polymer constituting at least about 60% by weight of the dry weight of the polymer matrix, and (ii) an amine-resistant capped silicone polymer constituting not more than about 30% by weight of the dry weight of the polymer matrix; and (b) scopolamine solubilized in the polymer matrix, wherein the flexible, finite system is substantially free of vinyl acetate and polar components. In some embodiments, the polymer matrix also comprises a non-polar penetration enhancer. Methods of making and using such flexible, finite systems also are described.
US08715718B2 Extracellular matrix production from nanoscale substrate
Compositions, methods, and kits for repair and production of extracellular matrix are provided. In the broad aspect, the composition comprises a ligand of α5β1 integrin attached to a surface of a nanoparticle composed of a protein, with a proviso that the protein is not fibronectin.
US08715710B2 Semi-solid delivery vehicle and pharmaceutical compositions for delivery of granisetron
A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
US08715708B2 Cyclic acetal biomaterials
A novel class of Cylic Acetal biomaterials (CABs) based on a cyclic acetal unit is disclosed and claimed by Applicants. Two novel biomaterials suitable for use in a variety of biological applications including in the orthopedic field for joint and cartilage replacement and/or repair, and bone cement. The biomaterials are comprised of either a network of monomers of 5-ethyl-5-(hydroxymethyl)-β,β-dimethyl-1,3-dioxane-2-ethanol diacrylate (EHD) and a hydrogel comprised of EHD and poly(ethylene glycol) diacrylate (PEG-EHD).
US08715707B2 Freeze-thaw method for modifying stent coating
Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents.
US08715705B2 Multilayer medical devices having an encapsulated edge and methods thereof
The present disclosure describes a medical which includes a body defining a conduit. The body includes a multilayer wall having at least one edge. The wall including a core layer positioned between an inner layer and an outer layer, wherein at least one of the inner and outer layers encapsulates the core layer along the edge.
US08715702B2 Deposition of lipophilic active material in surfactant containing compositions
The present invention relates to a controlled release carrier system that can be incorporated into rinse-off application products containing at least one surfactant such as heavy duty liquids (HDL), Rinse Cycle Fabric Softeners (RCFS), Shampoos, Hair Conditioners, Shower Gels, cleansing products, and that enhance deposition of lipophilic active materials like fragrance, fine perfumes, flavors and other volatile compounds onto a surface. The fragrance composition is encapsulated within a shell comprising a silicon-containing material and the shell has a mean diameter size which is lower than 30 micrometer. The surfactant composition containing the fragrance composition is washed off and the fragrance is progressively released.
US08715692B2 Modified RSV F proteins and methods of their use
The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
US08715691B2 Swine influenza hemagglutinin variants
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided.
US08715687B2 Immunogenic composition comprising variants of Staphylococcal clumping factor A
The present invention relates to ClfA polypeptides wherein amino acid Y474 or an amino acid adjacent to Y474 is mutated such that fibrinogen binding activity is decreased compared to an equivalent ClfA polypeptide without mutation of Y474 or an amino acid adjacent to Y474 as well as immunogenic compositions, vaccines, processes and uses of such mutated ClfA polypeptides.
US08715682B2 Means for the inhibition of anti-beta1-adrenergic receptor antibodies
Embodiments of the present invention provide for novel peptides of use for detection and/or inhibition of anti-β1-adrenergic receptor antibodies. Certain embodiments concern uses of cyclic and/or linear peptides. In other embodiments, the present invention relates to novel peptides of use in diagnostic and/or pharmaceutical compositions. Some embodiments concern diagnosing and/or treating cardiac conditions. Cardiac conditions of the instant invention can concern infectious heart disease, non-infectious heart disease, ischemic heart disease, non-ischemic heart disease, inflammatory heart disease, myocarditis, cardiac dilatation, idiopathic cardiomyopathy, idiopathic dilated cardiomyopathy, immune-cardiomyopathy, heart failure, and any cardiac arrhythmia condition.
US08715681B2 Minimal motifs of linear B-cell epitopes in L1 protein from human papillomavirus type 58 and their applications
Minimal Motifs of linear B-cell epitopes in L1 structure protein from human papillomavirus type 58 (HPV 58) and their applications are disclosed. Eighteen linear epitope motifs and their extended 8-mer peptides in the L1 protein from HPV 58 are described, which can be used as antigens separately or in combination to specifically detect the serum from subjects with HPV 58 infection, or to develop preventive or therapeutic multi-epitope peptide vaccines against HPV 58 by inducing humoral immunity. Of the eighteen B-cell epitope motifs, ten of them are 100% conservative and one is highly conservative among many homologous proteins of high-risk HPVs. They can be used as candidate “universal” epitopes to develop preventive or therapeutic HPV vaccines. The amino acid sequences of the epitope motifs and the 8-mer peptide formula of the invention are shown below in SEQ ID No. 1-2, 2B, 3, 3B, 4-18, 18B, 19, 19B, and 20-32.
US08715679B2 Pili from Mycobacterium tuberculosis
The present invention relates to pili obtained from Mycobacterium tuberculosis, methods of producing the pili and the use of the pili for inducing an immune response against Mycobacterium tuberculosis. The present invention also provides proteins and peptides which are constituents of the pili. Antibodies which bind to the pili are also provided.
US08715677B2 Immunological uses of immunomodulatory compounds for vaccine and anti-infectious disease therapy
Methods of enhancing immune response to an immunogen in a subject are disclosed. Also disclosed are methods of reducing the sensitivity to an allergen in a subject. The methods comprise the administration of an immunomodulatory compound in specific dosing regimens that result in enhanced immune response or reduced sensitivity.
US08715676B2 Production and uses of type I ribosome inactivating proteins
Described herein are methods to express and purify recombinant type 1 ribosome inactivating proteins. Included are methods for using recombinant cucurmosin as a therapeutic to treat cancer and infectious diseases.
US08715674B2 Antibodies binding to an intracellular PRL-1 or PRL-3 polypeptide
We provide an antibody capable of binding to an intracellular PRL-1 or PRL-3 polypeptide, in which the antibody is capable of binding to an epitope bound by antibody 269, antibody 223 or antibody 318. Such anti-PRL antibodies may be capable of binding to intracellular PRL-1 or PRL-3. They may be suitable for use as therapies against cancer or metastasis thereof, or in clinical diagnosis to identify PRL-3 or PRL-1 positive patients.
US08715667B2 Methods of treating patients having TLR3-positive cancer
The present invention relates to antibodies, antibody fragments, and derivatives thereof that specifically bind to TLR3 cell receptors present on the surface of cells. The invention also relates to hybridomas producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; pharmaceutical compositions comprising the same; methods of using the antibodies to detect TLR3 levels on the surface of cells, and the use of such antibodies and compositions for diagnostic or therapeutic purposes in subjects.
US08715662B2 Anti-trop-2 monoclonal antibodies and uses thereof in the treatment and diagnosis of tumors
The present invention teaches anti-Trop-2 monoclonal antibodies with high affinity and able to recognize different regions of the Trop-2 molecule, and uses thereof in the treatment and diagnosis of tumors, such as for example endometrium, breast, head and neck, colon-rectum, stomach, lung, ovary, prostate, pancreas, kidney, cervix and bladder (urothelial) tumors.
US08715660B2 Treatment of angiogenesis disorders
This invention concerns pathological angiogenesis and cancer, related treatment methods, and related compositions. Also disclosed are related diagnosis kits and methods.
US08715658B2 Methods for treating conditions mediated by the inflammatory cytokine cascade using GAPDH inhibitors
The present invention is directed to a method of treating a subject at risk for or having a condition mediated by an inflammatory cytokine cascade comprising administering to the subject an amount of a GAPDH inhibitor effective to treat the subject at risk for or having a condition mediated by an inflammatory cytokine cascade.
US08715655B2 Human anti-α9 integrin antibody
The present invention provides a human anti-α9 integrin antibody or an antibody fragment which specifically recognize human α9 integrin and mouse α9 integrin, inhibit interaction with their ligands, particularly, the antibody or antibody fragment which recognize loop regions of human and mouse α9 integrins, a gene encoding the antibody or antibody fragment, a recombinant expression vector containing the gene, a transformant harboring the gene, production method of human anti-α9 integrin antibody or antibody fragment using the transformant, and an agent for the prophylaxis or treatment of rheumatoid arthritis which contains the antibody or antibody fragment.
US08715645B2 Viral vectors encoding apoptosis-inducing proteins and methods for making and using the same
This invention discloses a novel method for propagation of viral vectors encoding proteins that induce apoptosis. The invention also discloses viral vectors produced by such methods and cells transfected with such vectors. Also disclosed are methods for suppressing T-lymphocyte-mediated graft rejection, for suppressing T-lymphocyte-mediated disease and for inducing apoptosis in cancer cells.
US08715644B2 Method for decreasing borborygmi by administering a bifidobacterium bacteria
The present invention relates to a method for decreasing borborygmi in a subject by administering a probiotic, preferably a bacteria of the Bifidobacterium genus, said method being on one aspect of the invention a non therapeutic method.
US08715641B2 Therapeutic amoeba and uses thereof
The present invention relates to amoebae (slime molds) and uses thereof. In particular, the present invention relates to the use of amoebae or their environmentally stable spores to treat microbial infections and other uses.
US08715640B2 Packaging cells for producing retrovirus pseudotyped with an E2 alphavirus glycoprotein
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
US08715636B2 Polysaccharide-based polymer tissue adhesive for medical use
Tissue adhesives formed by reacting an oxidized polysaccharide with a water-dispersible multi-arm polyether amine, wherein at least three of the arms are terminated by primary amine groups, are disclosed. The use of the tissue adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; drug delivery; anti-adhesive applications; and as a bulking agent to treat urinary incontinence are described.
US08715634B2 Volumizing compositions
The invention relates to compositions for keratin materials (hair or eyelashes) such as mascaras, topcoats and basecoats containing (a) at least one phosphate surfactant; and (b) at least one polyamide resin.
US08715633B2 Composition for keratin fibres
Conditioning and shine enhancing compositions dramatically and condition hair excellently in terms of combability, elasticity, smoothness and softness for keratin fibers especially human hair are disclosed. Particularly, the compositions disclosed comprise synthetic mica coated with metal oxide or oxides and having a volume particle size distribution of 1 to 750 μm at a concentration of 0.01 to 10% by weight, calculated to total composition, which gives hair shimmery shine.
US08715632B2 Compositions and methods for the protection of hair from treated pool water
Compositions for treating hair are disclosed. Methods of making and using compositions for treating hair are also disclosed.
US08715627B2 Protection against sunburn and skin problems with topical and orally-ingested dosages of zeaxanthin
Zeaxanthin is ingested orally at suitable dosages such as 30 to 100 mg/day for a span of 1 to 2 weeks, can give skin a darker tint that emulates a healthy suntan. In tests involving adults, it was found that zeaxanthin dosages of 30 to about 80 mg per day were sufficient to induce: (i) a mild but noticeable tinting, shading, or darkening of skin color, comparable to a mild suntan; (ii) a substantial increase in the person's ability to withstand elevated levels of sun or UV exposure without any subsequent pain or discomfort, and without the subsequent peeling and flaking that characterizes sunburns; and, (iii) an increased ability of reddened and sunburned skin to convert into intact skin that looks browned and healthily tanned. The topical application of zeaxanthin can further enhance the darkening of the skin.
US08715624B2 Stable liquid desoximethasone compositions with reduced oxidized impurity
The present invention relates to a stable liquid formulation comprising desoximetasone, isopropyl myristate, a C2-C4 alcohol and a stabilizing agent. Specifically, the present invention provides a liquid formulation comprising: a) about 0.01 wt % to about 2.5 wt % desoximetasone; b) about 10 wt % to about 70 wt % isopropyl myristate; c) about 20 wt % to about 70 wt % C2-C4 alcohol; and d) a stabilizing agent selected from the group consisting of an oleaginous vehicle and a propellant, wherein the stabilizing agent is in an amount sufficient to reduce the formation of less than about 1 wt % 17-carboxy-9α-fluoro-11β-hydroxy-16α-methyl-androsta-1,4-diene-3-one under an accelerated storage condition.
US08715621B2 Radical polarizing agents for dynamic nuclear polarization
The present invention provides a variety of radicals, which are useful as polarizing compounds. Exemplary radicals are represented by compounds of Structural Formulae (I), (II), (III) and (IV) as described herein.
US08715615B2 Recovery of high purity lead oxide from lead acid battery paste
The invention relates to the low temperature recovery of lead oxide (PbO) from lead acid battery paste through the preparation of lead carboxylate from the battery paste and the conversion of the lead carboxylate to PbO.
US08715613B2 Method for producing of ultra-clean and high-purity aqueous hydrogen peroxide solution
The present invention relates to a method for producing of ultra-clean and high-purity aqueous hydrogen peroxide solution. Industrial grade hydrogen peroxide is filtered by SBA-15 molecular sieve with which the chelator is loaded, and then it is further filtered by a hyperfiltration membrane to obtain the ultra-clean and high-purity aqueous hydrogen peroxide solution. The method provided in the present invention overcomes the problems such as complexity of operation, high energy consumption and high content of impurities in the product, and is suitable for continuous production on a large scale because of its simple equipment, simple operation, low energy consumption and stable quality of the product.
US08715610B2 Process for the preparation of graphene
The present invention relates to a process for the preparation of graphene which can be used in the development of graphene paper or films, graphene-based composites and articles for nanoelectronics, nanocomposites, batteries, supercapacitors, hydrogen storage and bioapplications. This process comprises reducing purified exfoliated graphite oxide in the presence of a base.
US08715609B2 Augmented reactor for chemical vapor deposition of ultra-long carbon nanotubes
Apparatus to produce carbon nanotubes (CNTs) of arbitrary length using a chemical vapor deposition (CVD) process reactor furnace is described, where the CNTs are grown axially along a portion of the length of the furnace. The apparatus includes a spindle and a mechanism for rotating the spindle. The spindle located within a constant temperature region of the furnace and operable to collect the CNT around the rotating spindle as the CNT is grown within the furnace.
US08715607B2 Method for separating and collecting carbon nanotube, and carbon nanotube
Metallic CNTs and semiconducting CNTs are efficiently separated from a CNT mixture of these CNTs, and semiconducting CNTs are separated by structure by using a method that enables separation in high yield in a short time period while conveniently enabling mass processing and automatic processing with inexpensive equipment.Multiple columns charged with gel are connected in series, and excess amounts of a CNT dispersion is passed through the columns to adsorb only the CNTs of a specific structure on the columns. The CNTs are then eluted with an elution to separate CNTs of different structures with high accuracy. The present technique represents a method that conveniently enables mass processing and automatic processing at high yield in a short time period with inexpensive equipment.
US08715605B2 Method for burning carbonated fuels with combustion smoke filtration before compression
A process for the combustion of a carbon-containing fuel, wherein the flue gases are filtered so as to achieve a solid particle concentration of less than 1 mg/m3 before compression, purification and sequestration or transport is presented.
US08715601B2 Diesel particulate control
A method and apparatus are provided for reducing emissions of particulates from diesel engines. Exhaust is passed through a diesel particular filter having at least two stages comprised of (a) a catalyst section having a platinum group metal catalyst on contact surfaces within the catalyst section and (b) a filter section comprised of passages effective to remove particulates from a moving stream of combustion gases generated by combusting the fuel in the engine and holding them therein to permit their oxidation. Carbon removal is enhanced by utilizing levels of platinum group metal composition, cerium compositions, fuels and/or optional chemical enhancers to generate NO2 in the catalyst section in amounts sufficient to form cerium nitrates in the filter section. The cerium oxide is associated with and maintains dispersion of the platinum in the filter section, and the cerium nitrates are available at the surface and within the soot particles to provide enhanced soot oxidation at a lower balance point.
US08715594B2 Apparatus for embedding tissue samples
A histology tissue embedding apparatus having an outlet for embedding medium and a generally horizontal working area beneath the outlet for supporting a cassette. The working area includes a generally horizontal trimming surface having corrugations and being substantially flush with the remainder of the working area.
US08715591B2 Microfluidic apparatus to control liposome formation
An apparatus to create a homogenous liposome population without post-processing using laminar flow/diffusive mixing, and for reducing waste discharge of the therapeutic or compound to be encapsulated and delivered by the liposomes.
US08715590B2 Multiplexed lateral flow assay arrays
A diagnostic test device comprising at least one membrane disposed in any of one, two, and three dimensions; at least one test sample fluid input port that receives and transfers at least one test sample fluid and onto the at least one membrane; at least one contiguous fluid flow manifold within the at least one membrane to multiplex or distribute the at least one test sample fluid; at least one contiguous fluid flow channel that operatively connects the at least one membrane to the at least one contiguous fluid flow manifold; at least one analyte assay test zone disposed within the at least one contiguous fluid flow channel; and at least one chemical capturing reagent disposed within the at least one analyte assay test zone, wherein multiple analyte assay test results are simultaneously obtained and in parallel in the diagnostic test device.
US08715586B2 Methods and systems for dispersing decontamination products
An electrostatic spraying system for decontamination of a vehicle is described. The system includes a wheeled platform sized to fit inside the vehicle, at least one tank operable to contain one or more decontaminant agents, the tanks supported by said wheeled platform, a plurality of nozzles affixed to the wheeled platform, wherein each nozzle is positioned for distribution of the decontaminant agents in at least one pre-determined direction, an electrostatic charging system connected to each of the nozzles for applying an electrostatic charge to the decontaminant agents as the agents are dispersed, and at least one compressor in communication with the tanks for pressurizing the decontaminant agents. The one or more compressors are capable of providing a pressure sufficient to provide a constant distribution of the decontaminant agents through the electrostatic nozzles.
US08715585B2 Mixing unit, mixing device, agitation impeller, pump mixer, mixing system and reaction device
A mixing unit and various applications of the mixing unit are described herein. The mixing unit includes: a stacked member in which three or more mixing elements are stacked; and a first plate and a second plate between which the stacked member is sandwiched and which are arranged opposite each other. In the mixing unit, the mixing elements have a plurality of first through holes, the second plate has an opening portion communicating with at least one of the first through holes in the mixing elements and the mixing elements are arranged such that part or all of the first through holes in one of the mixing elements communicate with other first through holes in the adjacent mixing element to allow fluid to be passed in a direction in which the mixing elements extend.
US08715584B2 Device for distributing feed and recovering effluents in a radial bed catalytic reactor
A radial bed catalytic conversion unit having an outer cylindrical chamber (1), an inner chamber (2) which is also cylindrical, the annular zone included between the outer chamber and the inner chamber, termed the reaction zone (I), is filled with catalyst under slow gravitational flow, and the feed is introduced via an inlet pipe (E), connected to an intermediate box (F) which is in turn connected to a plurality of distribution tubes (3) disposed inside the reaction zone (I) in the vicinity of the outer chamber (1).
US08715581B2 Modular power plant unconnected to the grid
The invention relates to a grid-connected power plant, having the following systems which are adjusted in their capacitance to each other: a) a wind power plant, water power plant, solar-thermal system and/or photovoltaic system for the production of electrical energy for operating the systems b) through f); b) a CO2 absorption system for the absorption of atmospheric CO2; c) a CO2 desorption system for the desorption of the CO2 gained in b); d) an electrochemical or solar-thermal H2 synthesis system for the operating system e); e) a synthesis system selected from the group catalytic methanol synthesis, catalytic DME synthesis, catalytic methane synthesis; f) a storage system selected from the group methanol storage system, DME storage system, methane storage system. The invention also relates to the use of such a power plant and methods for the operation of such a power plant.
US08715580B2 Thermal management exhaust treatment device and method of manufacture
An exhaust gas treatment device is disposed in an exhaust gas treatment system and comprises a rolled metal cylinder of corrugated metal sheet having longitudinally extending passages extending axially from an inlet end to an outlet end and a conduit disposed between layers of the rolled metal cylinder and configured for circulation of a heat transfer medium therethrough, the conduit extending axially and radially the rolled metal cylinder.
US08715577B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
US08715569B2 Post electron beam stabilization of polymeric medical devices
Methods are disclosed for chemically stabilizing a polymer stent after sterilization. The stent is exposed to a temperature above ambient for a period of time after radiation sterilization. The exposure reduces the concentration of free radicals generated by the radiation.
US08715567B2 Furnace tap hole flow control and tapper system and method of using the same
A molten metal flow controller (10) for a metal melt furnace having a tap hole (T) to release the molten metal from the furnace, where the controller (10) is configured to controllably release the flow of molten metal through the tap hole (T) using an actuator (14) that controllably moves a plunger (110) into and out of the tap hole (T) in response the increase or decrease in the molten metal flow rate through the tap hole (t) as measured by a sensor (130).
US08715566B2 Method and installation for the dry transformation of a material structure of semifinished products
An installation for the dry transformation of a material structure of semifinished products, particularly for dry bainitization, includes a quenching chamber and heating and/or cooling mechanism for setting the temperature prevailing on the inside of the quenching chamber, wherein the heating and/or cooling mechanism is developed as heating or cooling mechanism of a wall that borders on an inner chamber of the quenching chamber.
US08715565B2 Cooling system and cooling method of rolling steel
A cooling system that cools hot rolled long steel bar, provided with a plurality of chambers that are arranged along the longitudinal direction of the rolled steel bar. Each of the plurality of chambers is provided with a blow outlet that, facing from the chamber to the rolled steel bar, blows out compressed air for cooling that is introduced to the chamber from a gas inlet that is connected to the chamber; a nozzle plate having a plurality of nozzle holes that is provided at this blow outlet so as to face the rolled steel bar; a cooling water supply nozzle that supplies cooling water into the chamber; and a rectifying plate that is provided between the gas inlet and the cooling water supply nozzle, and that prevents the compressed gas for cooling that is introduced from the gas inlet from directly striking the nozzle plate. The cooling system of the present invention sprays a cooling medium that is produced by mixing the cooling water that is supplied from the cooling water supply nozzle and the compressed gas for cooling that is introduced from the gas inlet and rectified by the rectifying plate toward the rolled steel bar through the nozzle holes of the nozzle plate, and performs uniform cooling of the surfaces of the rolled steel bar.
US08715564B2 Method of fabricating an implantable medical device with biaxially oriented polymers
Methods and systems for manufacturing an implantable medical device, such as a stent, from a tube with desirable mechanical properties, such as improved circumferential strength and rigidity, are described herein. Improved circumferential strength and rigidity may be obtained by inducing molecular orientation in materials for use in manufacturing an implantable medical device. Methods of inducing circumferential molecular orientation by inducing circumferential flow in a molten polymer are disclosed.
US08715561B2 Assembling and shaping laminate panel
A method of assembling and shaping a laminate panel. An intermediate member is mounted on a lay-up table and a lay-up is assembling by laying a series of plies onto the intermediate member on the lay-up table. The intermediate member and the lay-up are then removed from the lay-up table and placed them on a shaped surface. The lay-up is then forced against the shaped surface, via the intermediate member, in a manner that modifies the shape of the lay-up to form a shaped laminate panel. Finally the shaped laminate panel is removed from the intermediate member. The lay-up table can thus support the flexible intermediate member during assembly, and can be relatively flat to enable the lay-up to assembled by an automated process.
US08715559B2 Non-porous sinter molded article of tetrafluoroethylene resin, expanded tetrafluoroethylene resin molded article, producing methods therefor, composite member, filter, impact deformation absorber and sealing material
A tetrafluoroethylene resin molded article obtained by fusing PTFE by heating a tetrafluoroethylene resin by heating, and then executing a gradual cooling or a cooling including a holding at a temperature equal to or higher than 313° C. and lower than 321° C. for 10 minutes or longer, and having, when heated to 365° C., then cooled to 245° C. with a rate of −1° C./min, and then heated to 365° C. with a rate of 10° C./min, a heat of fusion which, within a range from 296 to 343° C., is equal to or larger than 32 J/g and less than 47.8 J/g, a porous article obtained by expanding the molded article, and a composite article, a filter, an impact deformation absorber and a sealing material utilizing the molded article or the porous article.
US08715558B2 Capillary electrophoresis chips
A seamless microchannel with aligned microelectrodes structure can be prepared to include a polymeric body defining a surface of a seamless microchannel. The microchannel is seamless in that it is formed by a single body of material having a conduit that is open at one surface and extends to another opening aligned with microelectrodes in another surface of the body. The rest of the microchannel is closed and defined by the single body of material. The seamless microchannel structure can be used in methods that include biosensors, coupling waveguides, capillary electrophoresis chips, microreactors, polymerase chain reaction-chips, and solving mathematical problems.
US08715556B2 Gas turbine engine blade for aircraft and manufacturing method thereof
A gas turbine engine blade for aircraft which has a 3-dimensional blade surface shape twisted around a center line at an angle of 45 degrees or more and 70 degrees or less, wherein the aforementioned blade is provided with multiple composite material prepregs which contain reinforced fiber and which are integrally molded after being laminated in the thickness direction, and the aforementioned reinforced fiber runs continuously without interruption within each layer of the aforementioned composite material prepregs.
US08715551B2 Plastic product with three dimensional pattern and manufacturing method of the same
A plastic product having patterns in three dimensions includes an injecting base and a first film adhered to one side of the base. The first film includes a first pattern away from the base and a thickening layer attached to the first pattern. The first pattern is positioned between the thickening layer and the first film. A first raised portion is formed on the first film and inserted into the base.
US08715550B2 Methods of manufacturing formaldehyde-free molded products and related parts
The present invention provides a moldable mixture containing large portion of agricultural fibers and small portion of a binding agent and a flow-promoting filler material. The moldable mixture is substantially free of formaldehyde, with low moisture content and high draw ratio. The present invention also provides methods of manufacturing molded products and related parts, based on the claimed moldable mixture. Molded products (830) and related parts such as runner (810) and plank (820) with light weight, high density and more complex profile are manufactured by the claimed methods including steps of providing required materials for a moldable mixture, mixing the provided materials to form a moldable mixture, shaking the moldable mixture in preparing for compression molding and compression molding the moldable mixture to form molded products and related parts.
US08715546B2 Method and material kit for the production of tooth replacement parts
The process for producing tooth replacement parts is characterized in that curable tooth replacement material is introduced into a first mold of part of the human dentition, a positive model produced from a second mold is pressed into this material and the tooth replacement material remaining after the pressing-in is allowed to cure to form the tooth replacement part(s).
US08715538B2 Thermoelectric conversion material and producing method thereof; and thermoelectric conversion element using the same
Thermoelectric conversion materials, expressed by the following formula: Bi1-xMxCuwOa-yQ1yTeb-zQ2z. Here, M is at least one element selected from the group consisting of Ba, Sr, Ca, Mg, Cs, K, Na, Cd, Hg, Sn, Pb, Mn, Ga, In, Tl, As and Sb; Q1 and Q2 are at least one element selected from the group consisting of S, Se, As and Sb; x, y, z, w, a, and b are 0≦x<1, 0
US08715533B2 Dielectric raw material, antenna device, portable phone and electromagnetic wave shielding body
There are provided a high-permittivity dielectric raw material, an antenna device using the raw material and being useful as, especially, the built-in antenna device of a portable phone; a portable phone which can be reduced in weight, thickness and size, with an antenna radiation efficiency improved, and an electromagnetic wave shielding body for effectively shielding electromagnetic wave from an electric cooker.A dielectric raw material A having carbons dispersed in a silicone rubber base material 1, wherein, in any one of dielectric raw materials A, 1) containing 150 to 300 pts.wt. of carbons per 100 pts.wt. of silicone rubber, 2) formed by crosslinking and molding a mixture of non-crosslinked silicone rubber, non-crosslinked organic polymer and carbons, and 3) formed by combining and blending at least two kinds of carbons having different shapes and selected from spherical carbon 2, flat carbon, carbon fiber with a specific aspect ratio, carbon nanotube and conductive carbon 3, carbons are unevenly distributed in a silicone rubber base material 1 or carbons are contained with at least part of them contacting each other.
US08715532B2 Reduced graphene oxide doped with dopant, thin layer and transparent electrode
Disclosed herein is a reduced graphene oxide doped with a dopant, and a thin layer, a transparent electrode, a display device and a solar cell including the reduced graphene oxide. The reduced graphene oxide doped with a dopant includes an organic dopant and/or an inorganic dopant.
US08715530B2 Fluorescent pastes and films
A fluorescent paste that can form a fluorescent film and can be manufactured without a binder resin and has a high recording density and peel resistance Fluorescent fine particles each coated with a film formed of a film compound having a reactive group and a curing agent having a plurality of crosslinking reaction groups each reacting with the reactive group to form bonds are blended with a solvent to manufacture fluorescent paste. The fluorescent paste is applied to a substrate coated with a film formed of a second film compound having a second reactive group and is cured by crosslinking reactions between the reactive group and the second reactive group, and the crosslinking reaction groups to form a fluorescent film.
US08715528B2 Liquid fluorescent composition and light emitting device
The invention discloses a reflective liquid crystal material formulation, wherein a liquid crystal component of high dielectric anisotropy is employed to lower the driving voltage. By modulating the addition ratio of the high dielectric anisotropy components, reflective liquid crystal compositions of different reflective colors can be driven by a single driving voltage. The invention also provides a reflective bistable display using the above formulation.
US08715526B2 Fully-aromatic thermotropic liquid crystal polyester resin composition, molded object, and LED reflector
The fully-aromatic thermotropic liquid crystal polyester resin composition of the present invention comprises 100 parts by mass of a fully-aromatic thermotropic liquid crystal polyester; and 50 to 150 parts by mass of titanium oxide, wherein the fully-aromatic thermotropic liquid crystal polyester comprises a repeating structural unit represented by the following formula (1), a repeating structural unit represented by the following formula (2), and a repeating structural unit represented by the following formula (3), and comprises 65 mole % to 78 mole % of the repeating structural unit represented by the formula (1). wherein X and Y each represent a divalent group having an aromatic ring.
US08715525B2 Manufacturing method of electrode material
One object is to provide a manufacturing method of an electrode material with which a characteristic of a power storage device can be improved. In a manufacturing method of an electrode material comprising a compound represented by a general formula A2-aMSiO4 (A represents an alkali metal, M represents a transition metal, and a represents 0≦a<2), a mixed material is formed by mixing a compound that is a supply source of A, a compound that is a supply source of M, and a compound that is a supply source of Si; a flux is mixed into the mixed material after the mixed material is subjected to a heat treatment at a temperature of 400° C. or lower and pulverized; and the mixed material into which the flux is mixed is subjected to a heat treatment at a temperature of 700° C. or lower in an inert gas atmosphere.
US08715521B2 Absorption cycle utilizing ionic liquid as working fluid
The present invention relates to an absorption cycle comprising a refrigerant pair comprising at least one refrigerant and at least one ionic liquid. The present invention also provides an absorption cycle that utilizes fluorocarbon gases in fluorinated ionic liquids. The present invention also provides a method of cooling using an absorption cycle comprising a refrigerant pair comprising at least one refrigerant and at least one ionic liquid. The present invention also provides a method of heating using an absorption cycle comprising a refrigerant pair comprising at least one refrigerant and at least one ionic liquid.
US08715516B2 Optical element and method of manufacturing optical element with each of first and second layers having a repetition structure
An optical element having a three-dimensional structure which can function in a visible range and can improve adherence at a structural interface of the element, and a method of manufacturing the optical element. The optical element includes a substrate, and at least a first layer and a second layer on the substrate are manufactured such that each of the first layer and the second layer has a repetition structure of spaces and structural parts at a pitch equal to or less than a wavelength of visible light, and at an interface between the first layer and the second layer, overlapped structures are provided in which the repetition structure of the first layer and the repetition structure of the second layer overlap in a stack direction of the layers.
US08715512B2 Systems and methods for liquid separation
An apparatus and method for separating components of a fluid mixture. The apparatus includes a vortex generation zone shaped as an inverse truncated cone, a solids collection zone, a separation zone, one or more fluid inlets, one or more gas inlets, one or more fluid outlets, and one or more gas outlets. Gas is introduced into fluid in the vortex separation zone to facilitate the separation of components of the fluid mixture.
US08715511B2 Method and apparatus for sewage grit removal
Apparatus and method are provided for separating grit from liquid sewage while retaining organic solids in suspension. A sustained rotational liquid sewage first fluid flow, an induced upward liquid sewage second fluid flow, and a sustained rotational liquid sewage third fluid flow are employed in an apparatus having a cylindrical grit settling main chamber, a grit storage secondary chamber including a central grit settling access top mouth opening, a vertical shaft, a means for causing rotation of the vertical shaft, and a partition extending transversely through the main chamber and forming upper and lower subchambers. A fluid flow speed gradient is established between the liquid sewage third fluid flow and the liquid sewage first fluid flow. In this manner, grit is separated from liquid sewage.
US08715509B2 Tanning wastewater treatment and reuse apparatus and method therefor
A tanning wastewater treatment and reuse apparatus includes a coarse filter, a regulation pool, a hydraulic sieve, a desulfurization pool, a first nanocatalytic electrolyzer, a flocculation pool, a first settling pool, a flotation device, a biochemical pool, a second settling pool, a second nanocatalytic electrolyzer, a fine filter, and a compressor. Also provided is a tanning wastewater treatment and reuse method includes the steps of desulfurization, first nanocatalytic electrolysis, flocculation, biochemical treatment, second catalytic electrolysis, and filtration. The invention allows high CODCr removal rate, reduced chemical agent consumption, reduced sludge formation, thorough treatment, and high water reuse rate.
US08715502B1 Hoss' 4-stage biological nutrient removal (BNR) activated sludge process for removal of total phosphate and total nitrogen to a level below 1.0 mg/l without any chemical coagulation process such as alum or ferric chloride used for phosphorous removal
A biological nutrient removal (BNR) system to treat a typical U.S. municipal/domestic wastewater. This BNR system consists of four main directly interflowing of anaerobic, aerobic, anoxic and re-aeration. In the municipal/domestic wastewater treatment industry, the past multi-stage suspended waste activated sludge treatment facilities have been adding coagulant chemicals such as alum to remove total phosphorous (TP) and total nitrogen (TN) to 1.0 mg/l and 3.0 mg/l, respectively. This BNR system is a unique activated sludge biological configuration capable of treating wastewater biologically for clarifier effluent TP and clarifier effluent TN to a level less than 1.0 mg/l for each pollutant without any coagulant chemical additions.
US08715501B2 Solid waste digestion system
A system for digesting biodigestible feed that preferably includes the steps of comminuting the feed, introducing feed, an oxygen-containing gas, an accelerant, and bacteria into a digestion zone, the bacteria being suitable for digesting the feed under aerobic, anaerobic, and anoxic conditions. The contents of the digestion zone can be changed from aerobic operation to either anoxic or anaerobic operation, or vice versa, without changing the bacteria in the digestion zone.