最新美国发明专利第2013-12-10期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US08604236B2	Catalyst system A continuous carbonylation process for high turnover carbonylation, and a carbonylation reaction medium and product stream thereof. The process comprises carbonylating an ethlenically unsaturated compound with carbon monoxide in the presence of a source of hydroxyl groups and a catalyst system. The catalyst system comprising: (a) a bidentate phosphine, arsine or stibine ligand; and (b) a catalytic metal selected from a group VIB or group VIIIB metal or a compound thereof. The catalytically active concentration of said catalytic metal, measured as the ACCF (product Kg·hr−1·Dm−3), is maintained at less than 0.5.
US08604234B2	Method for preparing acrolein from glycerol by catalytic dehydration of glycerol using a heteropolyacid catalyst The invention relates to a method for preparing acrolein from glycerol or glycerin, according to which dehydration of glycerol or glycerin is carried out in the presence of a catalyst which consists in at least one silica modified with zirconium dioxide, titanium dioxide or tungsten trioxide or any combination of these oxides, and a heteropolyacid. This method may be used for making 3-(methylthio)propionic aldehyde (MMP), 2-hydroxy-4-methylthiobutyronitrile (HMBTN), methionine or its analogs, from acrolein.
US08604231B2	Metal complexes for chemical vapour deposition of platinum The invention relates to platinum complexes, to a method for preparing the same and to the use thereof for the chemical vapor deposition of metal platinum. The chemical vapor deposition of platinum onto a substrate is made from a platinum organo-metal compound the includes a ligand with a cyclic structure including at least two non-adjacent C═C double bonds, and the platinum organo-metal compound has a square-lane structure in which the platinum is bonded to each of the C═C double bonds of the ligand, thereby forming a (C═C)—Pt—(C═C) of 60° to 70°.
US08604221B2	Production method of halogen-substituted phthalide Disclosed is a method for producing a halogen-substituted phthalide, which includes a reaction step of reacting a halogen-substituted phthalic anhydride with sodium borohydride.
US08604218B2	Cytoskeletal active rho kinase inhibitor compounds, composition and use The present invention is directed to synthetic cytoskeletal active compounds that are inhibitors of rho-associated protein kinase. The present invention is also directed to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The invention is additionally directed to a method of preventing or treating diseases or conditions associated with cytoskeletal reorganization. In one embodiment of the invention, the method treats increased intraocular pressure, such as primary open-angle glaucoma. The method comprises administering to a subject a therapeutically effective amount of a cytoskeletal active compound of Formula I or Formula II, wherein said amount is effective to influence the actomyosin interactions, for example by leading to cellular relaxation and alterations in cell-substratum adhesions.
US08604216B2	Desferrithiocin derivatives and methods of use thereof Compounds represented by structural formulas such as Structural Formula (I): are highly efficient in clearing excess iron from an organism. The invention also discloses methods of treating conditions such as metal overload, oxidative stress, and neoplastic and preneoplastic conditions.
US08604212B2	Anti-shock agent comprising diaminotrifluoromethylpyridine derivative Septic shock is known to lead to, at the end stage, systematic inflammatory reaction syndrome and multiple organ failure (MOF) and cause the patients' death. In both diseases, the patient dies finally of MOF, and the infiltration by inflammatory cells plays a key role for MOF. Thus, development of therapeutic agents for septic shock by suppressing the infiltration by inflammatory cells has been desired.To provide a therapeutic or preventive agent for shock, comprising as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a cycloalkylcarbonyl group, an alkenylcarbonyl group, a thiophenecarbonyl group or a benzoyl group which may be substituted by a halogen atom; and Y is an alkylsulfonyl group.
US08604210B2	Pyrazole derivatives, preparation method thereof, and composition for prevention and treatment of osteoporosis containing same The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.
US08604208B2	Polymorphs of sorafenib acid addition salts The present invention provides amorphous and crystalline forms of acid addition salts of sorafenib, pharmaceutical compositions comprising them and their use for the treatment of cancer. The present invention also provides processes for the preparation of acid addition salts of sorafenib.
US08604204B2	Fluorescent dyes The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins, nucleic acids and cellular organelles. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified to provide beneficial properties.
US08604203B2	Modulators of cystic fibrosis transmembrane conductance regulator The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
US08604198B2	Salt of proline derivative, solvate thereof, and production method thereof The present invention provides 3-{(2S,4S)-4-[4-(3-methyl -1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2 -ylcarbonyl}thiazolidine (compound I) useful as a dipeptidyl peptidase-IV inhibitor, which has superior properties of stability and hygroscopicity, and reproducible crystal structure, and a production method thereof.
US08604194B2	Salts of O-desmethyl-venlafaxine Novel pharmaceutically acceptable salts of desvenlafaxine with physiologically ubiquitous ions selected from sugar acids and vitamins, processes for their preparation, pharmaceutical compositions containing them and uses therefor are described.
US08604192B2	Cyclohexenyl nucleic acids analogs The present disclosure describes cyclohexenyl nucleic acid analogs, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, cyclo-hexenyl nucleic acid analogs are provided, having one or more chiral substituents, that are expected to be useful for enhancing properties of oligomeric compounds including nuclease resistance and binding affinity. In some embodiments, the oligomeric compounds provided herein hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.
US08604191B2	Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3YLVINYL)pyrimidine The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-yl)pyrimidine, novel salt forms, and novel polymorphic forms of these salts.
US08604190B2	Hetero isonipecotic modulators of vanilloid VR1 receptor This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals.
US08604187B2	Compositions and methods of aloe polysaccharides The present invention describes a method for preparing a polymannan extract from freeze-dried aloe powder. The polymannan extract of the present invention is further used to formulate a sterile injectable formulation for the treatment of one or more cancers, leukemias and lymphomas, prostate cancer, breast cancer, and colon cancer, immune diseases, particularly immune related neoplasms, acquired immune deficiency syndrome, and hepatitis C.
US08604183B2	Compositions comprising alternating 2′-modified nucleosides for use in gene modulation The present invention provides compositions comprising at least one oligomeric compound comprising an alternating motif and further include a region that is complementary to a nucleic acid target. The compositions are useful for targeting selected nucleic acid molecules and modulating the expression of one or more genes. In preferred embodiments the compositions of the present invention hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. The present invention also provides methods for modulating gene expression.
US08604174B2	High affinity fully human monoclonal antibodies to interleukin-8 The present embodiments are related to high-affinity antibodies directed to IL-8, methods of making and characterizing such antibodies and uses of such antibodies. Isolated polynucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions (FR's) and/or complementarity determining regions (CDR's), are provided.
US08604170B2	Antibody against the CSF-1R The present invention provides antibodies specific for the CSF-1R, compositions comprising said antibodies and methods of treatment using such compositions.
US08604166B2	Melanoma antigen peptide and uses thereof The present invention relates to novel melanoma antigen peptides and specific T lymphocytes directed to said peptides and the use thereof for treating melanoma.
US08604164B2	High purity lipopeptides The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromatography and anion exchange chromatography. The invention also discloses a method of purifying daptomycin by modified buffer enhanced anion exchange chromatography. The invention also discloses an improved method for producing daptomycin by fermentation of Streptomyces roseosporus. The invention also discloses high pressure liquid chromatography methods for analysis of daptomycin purity. The invention also discloses lipopeptide micelles and methods of making the micelles. The invention also discloses methods of using lipopeptide micelles for purifying lipopeptide antibiotics, such as daptomycin. The invention also discloses using lipopeptide micelles therapeutically.
US08604160B2	Composite roofing overlay containing recycled paint waste and recycled crushed glass A composite roofing overlay containing paint waste is provided for use on a roof surface. The composite roofing overlay includes a bedding cement containing water-based paint waste and crushed recycled glass, a porous fabric embedded in the bedding cement, and at least one primer coat over the porous fabric and bedding cement. The composite roofing overlay may be used in combination with an overlying waterproof roofing membrane to provide an effective waterproof seal to new or existing roof structures.
US08604156B2	Device and method for producing polybutylene succinate A device and a method for producing high-quality polybutylene succinate are provided. The method for producing polybutylene succinate comprises the steps of: preparing a raw-material slurry by mixing succinic acid or a derivative thereof with 1,4-butanediol in a raw-material slurry preparation tank; storing the raw-material slurry in a raw-material slurry storage tank while maintaining flowability; carrying out an esterification reaction of the raw-material slurry in an esterification reactor; and synthesizing polybutylene succinate with a polycondensation reaction of the ester in a polycondensation reactor, in which the polycondensation reactor is divided, from the upstream side, into at least an initial polycondensation reactor, an intermediate polycondensation reactor, and a final polycondensation reactor, a catalyst is added in an amount from 1000 ppm to 3000 ppm in relation to succinic acid or a derivative thereof, the reaction time in the intermediate polycondensation reactor ranges from 0.25 hours to 0.75 hours, and the reaction temperature in the final polycondensation reactor ranges from 245° C. to 255° C.
US08604152B2	Anchored polysiloxane-modified polyurethane coatings and uses thereof A polymeric material, prepared by reacting a mixture comprising a polyorganosiloxane having one or more isocyanate-reactive functional groups, polyisocyanate, and polyol, is provided. The isocyanate-reactive functional groups, typically one or two, are attached to only a single end of the polyorganosiloxane chains. The polymeric material may be used to form coatings on a substrate and to inhibit fouling on surfaces exposed to aqueous conditions.
US08604148B2	Functionalization of vinyl terminated polymers by ring opening cross metathesis This invention relates to a polymer of a cyclic olefin and a vinyl terminated macromonomer, and processes for the production thereof.
US08604144B2	Procatalyst composition with substituted amide ester internal electron donor Disclosed are procatalyst compositions having an internal electron donor which includes a substituted amide ester and optionally an electron donor component. Ziegler-Natta catalyst compositions containing the present procatalyst compositions exhibit improved catalyst activity and/or improved catalyst selectivity and produce propylene-based olefins with broad molecular weight distribution.
US08604141B2	High metathesis activity ruthenium and osmium metal carbene complexes Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The carbene compounds are of the formula where M is Os or Ru; R1 is hydrogen; R is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, and substituted or unsubstituted aryl; X and X1 are independently selected from any anionic ligand; and L and L1 are independently selected from any neutral electron donor. The ruthenium and osmium carbene compounds of the present invention may be synthesized using diazo compounds, by neutral electron donor ligand exchange, by cross metathesis, using acetylene, using cumulated olefins, and in a one-pot method using diazo compounds and neutral electron donors. The ruthenium and osmium carbene compounds of the present invention may be used to catalyze olefin metathesis reactions including, but not limited to, ROMP, RCM, depolymerization of unsaturated polymers, synthesis of telechelic polymers, and olefin synthesis.
US08604139B2	Extrusion profile articles Extrusion profile articles comprising a polyester having a dicarboxylic acid component and a glycol component. The dicarboxlyic acid component comprises at least 90 mole % terephthalic acid residues. The glycol component comprises at least 75 mole % ethylene glycol residues and 15 to 25 mole % residues of a difunctional glycol such as, for example, 1,4-cyclohexanedimethanol. Such extrusion profile articles can exhibit reduced haze, reduced sharkskin, and/or increased compatibility in PET recycling.
US08604136B2	Process for making dendritic hydrocarbon polymers A process for making a substantially saturated dendritic hydrocarbon polymer. The process has the following steps: (a) polymerizing an amount of one or more alkadiene monomers and/or one or more alkenylaromatic polymers under anionic conditions in the presence of a di- or tri-functional organic lithium initiator to produce a polyalkadiene defining a multiplicity of lithiated chain ends; (b) reacting the polyalkadiene with an amount of a tri- or di-functional silane coupling agent to form a dendritic polyalkadiene; and (c) hydrogenating the dendritic polyalkadiene to form a substantially saturated dendritic hydrocarbon polymer. Also a process for process for making a dendritic hydrocarbon polymer, comprising: (a) polymerizing an amount of one or more alkadiene monomers and/or one or more alkenylaromatic polymers under anionic conditions in the presence of a di- or tri-functional organic lithium initiator to produce a hydrocarbon polymer defining a multiplicity of lithiated chain ends; and (b) reacting the hydrocarbon polymer with an amount of a tri- or di-functional silane coupling agent to form a dendritic hydrocarbon polymer.
US08604132B2	Rheology modifying star macrmolecules for fracking fluids and home care A polymer composition comprising star macromolecules is provided. Each star macromolecule has a core and five or more arms, wherein the number of arms within a star macromolecule varies across the composition of star molecules. The arms on a star are covalently attached to the core of the star; each arm comprises one or more (co)polymer segments; and at least one arm and/or at least one segment exhibits a different solubility from at least one other arm or one other segment, respectively, in a reference liquid of interest.
US08604130B2	Adhesive composition and optical member using the same An adhesive composition includes a (meth)acrylic copolymer, the (meth)acrylic copolymer containing about 92 to about 99.7 parts by weight of a moiety derived from a (meth)acrylic acid ester monomer, and about 0.3 to about 8 parts by weight of at least one of a moiety derived from a carboxyl group-containing monomer and a moiety derived from a hydroxyl group-containing (meth)acrylic acid monomer, the (meth)acrylic copolymer having a weight average molecular weight of about 500,000 g/mol to about 2,000,000 g/mol, a carbodiimide curing agent, and an oligomeric silane coupling agent.
US08604114B2	Aromatic acylation with cyclic anhydride for plasticizer production Provided is a process for making non-phthalate plasticizers, by acylating an aromatic compound with a succinic anhydride to form a keto-acid, and then esterifying the keto-acid with C4-C13 OXO-alcohols to form a plasticizer compound. The aromatic rings of the aromatic compound may also be optionally hydrogenated.
US08604110B2	Alkyl aromatic plasticizers and methods of making Provided are compounds of the formula: wherein m=0-3 and n=0-3, and R1 represents CxH2x wherein x=0 to 4 or cyclohexane; R2 represents H, a C1-C6 alkyl group at any of the ortho-, meta- or para-positions, a residue including heteroatoms chosen from O, N, and S, or mixtures thereof; and R3 and R4 represent hydrocarbon residues of OXO-C5-C9 alcohols which are different isomers of equal carbon number or different in carbon number. Also provided are processes for making the compounds and plasticized polymer compositions containing said compounds.
US08604108B2	Method for producing mono-hydroxyfunctionalized dialkylphosphinic acids and esters and salts thereof by means of acroleins and use thereof The invention relates to a method for producing mono-hydroxyfunctionalized dialkylphosphinic acids and esters and salts thereof by means of acroleins, characterized in that a) a phosphinic acid source (I) is reacted with olefins (IV) to yield an alkylphosphonic acid, salt or ester (II) thereof in the presence of a catalyst A, b) the thus obtained alkylphosphonic acid, salt or ester (II) thereof is reacted with compounds of formula (V) to yield a mono-functionalized dialkylphosphinic acid derivatives (IV) in the presence of a catalyst B, and c) the thus obtained mono-functionalized dialkylphosphinic acid derivatives (VI) are reacted to yield a mono-hydroxyfunctionalized dialkylphosphinic acid derivative (III) in the presence of a catalyst C, wherein R1, R2, R3, R4, R5, R6, R7 are the same or different and stand independently of each other, among other things, for H, C1-C18 alkyl, C6-C18 aryl, C6-C6-C18 aralkyl, C6-C18 alkylaryl, and X stands for H, C1-C18 alkyl, C6-C18 aryl, C6-C18 aralkyl, C6-C18 alkylaryl, Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Zn, Ce, Bi, Sr, Mn, Cu, Ni, Li, Na, K and/or a protonized nitrogen base, and the catalyst A and C are formed by transition metals and/or transition metal compounds and/or catalyst systems composed of a transition metal and/or a transition metal compound and at least one ligand, and catalyst B is formed by compounds forming peroxides and/or peroxo compounds and/or azo compounds and/or alkali metals and/or alkaline earth metals, alkali hydrides, alkaline earth hydrides and/or alkali alcoholates and alkaline earth alcoholates.
US08604106B2	Polypropylene based formulations A polypropylene composition comprising polypropylene impact copolymer or impact modified polypropylene and an effective flame retarding amount of a mixture of (i) tris(tribromoneopentyl) phosphate and (ii) a carbon-carbon initiator, wherein the composition meets a UL 94 rating of V-1 or V-0, said composition being substantially free from antimony trioxide. A method for improving the flame retarding rating of a polypropylene composition is also disclosed.
US08604105B2	Flame retardant copolyester compositions The present invention relates to the combination of halogen-free flame retardant additives in a copolyester to improve the flame retardant properties of the copolyester composition while retaining impact properties, methods of making the copolyester composition and articles made from the copolyester composition. More specifically, the present invention relates to the use of a nitrogen containing flame retardant and a metal phosphorous-containing compound in copolyester compositions to improve the flame retardant properties while retaining impact properties, methods of making said copolyester compositions and articles therefrom.
US08604104B2	Cellulose ether composition for dry mortar formulations The present invention relates to a cellulose ether composition for use in the preparation of dry mortar formulations, especially of cementitious bound tile adhesives (CBTA). The invention further relates to a dry mortar formulation comprising said cellulose ether composition. Furthermore, the invention is directed to a method of improving the slip resistance of a dry mortar formulation without deteriorating the mechanical strength and the open time of the cured dry mortar formulation.
US08604102B2	Thermosetting composition The disclosure provides a thermosetting composition, including: (a) about 1-35 wt % of an oligomer, wherein the oligomer is obtained by reacting a liquid epoxy resin with an aromatic primary amine having four active hydrogen atoms, and the liquid epoxy resin and the primary amine have an equivalent mole ratio of 1:0.15-1:2.50; (b) about 5-10 wt % of a long chain resin; (c) about 50-80 wt % of an epoxy resin having at least two functional groups; and (d) about 5-15 wt % of a plasticizer.
US08604101B2	Process for producing aqueous dispersions of thermoplastic polyesters The present invention relates to a process for producing aqueous dispersions of thermoplastic polymers which have a plurality of ester groups and/or carbonate groups in the main polymer chain and which have an acid number of less than 5 mg KOH/g, in particular at most 3 mg KOH/g, and which have a zero-shear viscosity η0 (180° C.) of at least 60 Pa·s at 180° C. The invention also relates to the polymer dispersions obtainable by said process, and to the use thereof.
US08604100B2	Ink composition for oil-based ballpoint pen Disclosed are an ink composition for oil-based ballpoint pens which exhibits soft writing sensation due to low viscosity of 300 to 3000 cps, enables writing even at low temperatures and thus exhibits superior stability, and is free of leakage (of ink), and an oil-based ballpoint pen using the same.
US08604098B2	On-demand photoinitiated polymerization Compositions and methods for adjustable lenses are provided. In some embodiments, the lenses contain a lens matrix material, a masking compound, and a prepolymer. The lens matrix material provides structure to the lens. The masking compound is capable of blocking polymerization or crosslinking of the prepolymer, until photoisomerization of the compound is triggered, and the compound is converted from a first isomer to a second isomer having a different absorption profile. The prepolymer is a composition that can undergo a polymerization or crosslinking reaction upon photoinitiation to alter one or more of the properties of the lenses.
US08604095B2	Radiation-curable ink composition, ink jet recording method, and recorded matter A radiation-curable ink composition contains (A) aminoacrylate at 1 mass % to 10 mass %, inclusive, (B) phenoxyethyl acrylate at 20 mass % to 50 mass %, inclusive, and (C) tetraethylene glycol diacrylate at 1 mass % to 20 mass %, inclusive, in its reaction component, as well as (E) bis(2,4,6-trimethylbenzoyl)-phenylphosphine oxide at 3 parts by mass to 8 parts by mass, inclusive, (F) 2,4,6-trimethylbenzoyl-diphenyl-phosphine oxide at 3 parts by mass to 5 parts by mass, inclusive, in 100 parts by mass of the reaction component, and (G) diethylthioxanthone at 1 part by mass to 3 parts by mass, inclusive, in 100 parts by mass of the reaction component.
US08604091B2	Non-isocyanate spray foam One- and two-part spray non-isocyanate foams that include an amide-based oligomer containing pendant carboxylic acid and a polyfunctional aziridine crosslinking agent is provided. The amide oligomer typically contains urea links, urethane links or both groups. Additionally, the foams may include one or more plasticizer, a non-functionalized resin, a surfactant, and/or a thickening agent or rheology modifier. The amide oligomer does not contain any isocyanate groups, and, as a result, there are no free isocyanate moieties generated during formation of the foam that may be potentially hazardous to workers installing the foam. The presence of the urethane segments on the oligomer permits for the generation of a polyurethane foam without the drawbacks of conventional polyurethane foams. The foams may be used to fill cavities, cracks, gaps and crevices, such as around windows and doors, and may also be used in flash and batt systems.
US08604090B2	Process for dissolution of highly fluorinated ion-exchange polymers Highly fluorinated ion-exchange polymers achieve dissolution in aqueous tetrahydrofuran at lower pressures and temperatures than in other solvents, with few or no side products being formed.
US08604087B2	Composition for treating or preventing amyloid-related diseases comprising 4-O-methylhonokiol Disclosed is a composition for treating or preventing amyloid-related diseases including 4-O-methylhonokiol as an active ingredient. More specifically, a pharmaceutical composition including 4-O-methylhonokiol, which is effective for treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorder, defective memory, amyloidosis, etc. is disclosed. The inventors of the present disclosure have found out for the first time that 4-O-methylhonokiol inhibits the production of β-amyloid. It has been confirmed to be useful in treating or preventing amyloid-related diseases. Through animal tests including water maze test and passive avoidance test on mice, 4-O-methylhonokiol has been confirmed to be effective for amyloid-related diseases such as Alzheimer's disease, defective memory, cognitive disorder, and the like. It was further confirmed through acetylcholinesterase activity inhibition test using mouse brain cortex and hippocampus tissue that they are particularly effective in treating or preventing Alzheimer's disease among the amyloid-related diseases.
US08604086B2	Sulfonic acid and aldehyde condensation polymers for the treatment and prevention of HPV The present invention relates to a method of treating and preventing a papillomavirus infection in an individual, comprising administering to the individual a therapeutically effective amount of a condensation polymer of an aromatic sulfonic acid and an aldehyde, or a pharmaceutically acceptable salt thereof.
US08604085B2	Bupropion hydrobromide polymorphs Polymorphous and amorphous forms of bupropion hydrobromide are described.
US08604082B2	Method to treat premature ejaculation in humans The present invention belongs to the fields of pharmacology, medicine and medicinal chemistry, and provides methods and compositions for treating sexual dysfunction; more particularly, the invention relates to treatment of premature ejaculation in humans.
US08604081B2	Topical composition containing ibuprofen The present invention generally relates to the transdermal delivery of various compositions. In some aspects, the transdermal delivery may be facilitated by the use of a hostile biophysical environment. One set of embodiments provides a composition for topical delivery comprising ibuprofen and/or an ibuprofen salt, a nitric oxide donor, and optionally, a hostile biophysical environment. In some cases, the composition may be stabilized using a stabilization polymer such as xanthan gum, KELTROL® BT and/or KELTROL® RD; propylene glycol; and a polysorbate surfactant such as Polysorbate 20, which unexpectedly provides temperature stability to the composition, e.g., at elevated temperatures such as at least 40° C. (at least about 104° F.), as compared to compositions lacking one or more of these.
US08604077B2	Ketal compounds from polyols and oxocarboxylates Novel ketal compounds can be made from an oxocarboxylate and a triol. Novel polymeric structures are, in turn, synthesized from the ketal compounds. Such ketal compounds and associated polymers are useful in a broad range of applications as a substitute for materials derived from petroleum or other such nonrenewable resources.
US08604075B2	Methods and compositions for improving cognitive function This invention relates to treating age-related cognitive impairment. This invention in particular relates to the use of inhibitors of synaptic vesicle protein 2A (SV2A), such as levetiracetam, seletracetam, and brivaracetam, in improving cognitive function in subjects that exhibit age-related cognitive impairment or are at risk thereof, including, without limitation, subjects having or at risk for Mild Cognitive Impairment (MCI), Age-related Cognitive Decline (ARCD) or Age-Associated Memory Impairment (AAMI).
US08604073B2	Antimicrobial composition An antimicrobial composition comprising (a) a cationic surfactant derived from the condensation of fatty acids and esterified dibasic amino acids, such as lauric arginate and (b) an antibiotic, such as of β-lactam antibiotics, polypeptides, quinolones. The composition may be used as a stand alone antimicrobial formulation, or in combination with medical articles or medical devices.
US08604071B2	Method for producing hydroxymethyl diphenyloxiranes and corresponding 1-azolylmethyl-1,2-diphenyloxiranes The present invention relates to a method for producing 1-hydroxymethyl-1,2-diphenyloxiranes from 2,3-diphenylpropenals by means of epoxidation and reduction. The formation of objectionable by-products can be suppressed in that the reduction is started before the 2,3-5 diphenylpropenal is completely converted. The hydroxymethyl diphenyloxiranes represent valuable intermediate products for producing 1-azolylmethyl-1,2-diphenyloxiranes, wherein the latter can be easily produced from said intermediate products by introducing the azolyl group.
US08604070B2	Use of inhibitors of the renin-angiotensin system It has been found that inhibitors of the rennin-angiotensin system are useful for the treatment or prevention of conditions associated with hypoxia or impaired metabolic function or efficiency. In particular, they may be used in connection with therapy of stroke or its recurrence, the acute treatment of myocardial infarction, and the treatment or prevention of wasting or cachexia, and are thus useful in treatment of the symptoms and signs of aging. These inhibitors may also be used to enhance function in healthy subjects.
US08604069B2	Amide compound and medicinal use thereof A compound of formula [I-W]: wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.
US08604067B2	ITE for cancer intervention and eradication A method of cancer intervention or eradication by administering an effective amount of an endogenous ligand for the aryl hydrocarbon (Ah) receptor (AhR) named ITE or one of its analogs (the active ingredient) to a subject with cancer is disclosed. An effective dose and dosing frequency of the active ingredient are determined by measuring its blood levels of the subject after dosing. The active ingredient formulated with a carrier system is applied topically, enterally, or parenterally to the subject. The formulated drug can also be administered together with one or more of other cancer therapeutic agents. A maintenance dosing is provided after the subject is free of cancer to insure the cancer eradication. Subjects with cancers of prostate, liver, lung, ovarian, and breast are preferably accepted for treatment.
US08604062B2	Process for the preparation of isoxazolyl-methoxy nicotinic acids The present invention relates to a process for the preparation of a compound of formula (I) wherein R1 and R2 are as defined herein, which is useful as an intermediate in the preparation of active pharmaceutical compounds.
US08604060B2	Use of antagonists of the CBI receptor for the manufacture of a composition useful for the treatment of hepatic diseases The invention relates to the use of antagonists to the CB1 receptor for the preparation of a composition for the treatment of hepatic diseases and preferably to the use of N-piperidino5 5-(4-chlorophenyl)-1-(2, 4-dichloropenyl)-4-methylpyrazole-3-carboxamide.
US08604056B2	Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor XIa inhibitors The present invention provides compounds of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, L1, M and R11 are as defined herein. The compounds of Formula (I) are selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors or dual inhibitors of fXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
US08604052B2	Indazole inhibitors of the WNT signal pathway and therapeutic uses thereof Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases due to mutations in Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
US08604048B2	Pyridocarbazole type compounds and applications thereof Pyridocarbazole-type compounds of formula (I): are provided as a medicament, and more particularly for application in anticancer chemotherapy. Also provided is a pharmaceutical composition with the compound and methods for preventing and/or treating neurodegenerative-type pathologies, such as Alzheimer's disease and schizophrenia, parasitoses, such as malaria, or glaucomas.
US08604041B2	Method of treating panic disorder The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1): wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
US08604039B2	Dihydrothienopyrimidines for the treatment of inflammatory diseases The invention relates to new dihydrothienopyrimidine of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein X is SO or SO2, but preferably SO, and wherein R1, R2 and R3 have the meanings given in the description, and which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.
US08604036B2	Pyridazinone derivatives Compounds of the formula (I), in which R1, R2, R3, W and D have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumors.
US08604029B2	2-[(2-substituted)-indolizin-3-yl]-2-oxo-acetamide derivatives as antifungal agents The invention provides compounds of formula (I), and pharmaceutically acceptable salts thereof wherein: R1, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. These compounds are useful in the manufacture of medicaments for use in the prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.
US08604028B2	Furopyridinyl-substituted 1,4-dihydropyridine derivatives and methods of use thereof This invention relates to novel 4-(furo[3,2-c]pyridin-2-yl)-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.
US08604027B2	Cyclic progestin regimens and kits A method of contraception is provided which involves delivery of 21 to 27 consecutive days of a progestin in the absence of an estrogen or other steroidal compound, followed by 1 to 7 days without an effective amount of an active agent. Also described is a pharmaceutically useful kit to facilitate delivery of this regimen.
US08604022B2	N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-3-yl]-4-(3,4-dimethylpiperazin-1-yl)benzamide and salts thereof There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
US08604021B2	Substituted arylamine compounds and methods of treatment The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity-related disorders, e.g., cardiovascular disease, digestive disease, respiratory disease, cancer and type II diabetes; and psychological disorders such as schizophrenia, are disclosed.
US08604019B2	Compounds for the treatment and prophylaxis of respiratory syncytial virus disease The invention relates to the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2 and X are as defined in the description and claims, which are useful for the treatment or prophylaxis of RSV infection.
US08604017B2	Azetidinyl diamides as monoacylglycerol lipase inhibitors Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
US08604015B2	Alkaloid ester and carbamate derivatives and medicinal compositions thereof Compounds according to formula (I) are effective for the treatment of broncho-obstructive and inflammatory diseases.
US08604013B2	Enhanced erythropoiesis and iron metabolism The present invention relates to methods for treating anemia in a subject having a low percent transferrin saturation by administering to the subject an effective amount of a compound that inhibits hypoxia-inducible factor prolyl hydroxylase activity.
US08604008B2	2-methylene-19,21-dinor-1α-hydroxy-bishomopregnacalciferol Compounds of formula I are provided where X1 and X2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
US08604005B2	Use of probiotics The invention relates to the use of probiotics in the manufacture of a composition for enhancing a metabolic profile in a subject. The probiotics are capable of preventing and treating diseases or disorders associated with an abnormal metabolic profile, especially a lipid profile by normalizing the profile. The probiotics are particularly effective in down-regulating levels of lysophosphatiydylcholines (LysoPCs) and ceramides.
US08603998B2	Modulators of cell cycle checkpoints and their use in combination with checkpoint kinase inhibitors In its many embodiments, the present invention provides a novel class of pyrimidine analogs of formula (V) as targeted mechanism-based modulators of cell cycle checkpoints. Cancers and/or malignancies can be treated by administration of a cell cycle checkpoint modulator of the invention. Also discussed are suitable combinations of the cell cycle checkpoint modulator with a checkpoint kinase inhibitor to produce synergistic apoptosis in cancer cells. The invention includes methods of treating cancers by administering the combination of the cell cycle checkpoint modulator and the checkpoint kinase inhibitor, pharmaceutical compositions comprising the activator as well as the combination and pharmaceutical kits.
US08603991B2	Individualized cancer therapy Methods for treating cancer that include (a) obtaining a specimen of cancer issue from a patient; (b) obtaining a specimen of normal tissue in the proximity of the cancer tissue; (c) extracting total protein from the cancer tissue and normal tissue; (d) obtaining a protein expression profile of the cancer tissue and normal tissue; (e) identifying a group of proteins that are expressed in the cancer tissue at significantly different levels than in the normal tissue; (f) identifying one or more prioritized proteins from the group of proteins, which will serve as the target for an RNA interference molecule (RNAi), which, when provided to a patient, will reduce the expression level of the one or more prioritized proteins using both cleavage-dependent and cleavage-independent pathways of the RNA-induced silencing complex (RISC).
US08603988B2	Ionic complexes The present invention provides a phosphopeptide or phosphoprotein (PP) stabilized amorphous calcium phosphate or amorphous calcium fluoride phosphate complex having a calcium ion greater than about 30 moles of calcium per mole of PP.
US08603987B2	Monoclonal antibodies to fibroblast growth factor receptor 2 The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.
US08603986B2	Compounds and methods for modulating cadherin-mediated processes Peptides comprising a cadherin cell adhesion recognition (CAR) sequence, and compositions comprising such peptides, are provided. Methods of using such peptides for modulating cadherin-mediated processes in a variety of therapeutic contexts are also provided. Methods are also provided for identifying compounds that are capable of modulating cadherin-mediated processes.
US08603983B2	Targeted delivery of botulinum toxin for the treatment and prevention of trigeminal autonomic cephalgias, migraine and vascular conditions Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are delivered focally, targeting the nerve endings of the trigeminal nerve, the occipital nerve and the intranasal terminals of the parasympathetic fibers originating in the Sphenopalatine ganglion. The administration preferably targets the extracranial nerve endings of the trigeminal nerve in the temporal area, the extracranial occipital nerve endings in the occipital area, and the intranasal terminals of the trigeminal nerve and parasympathetic fibers originating in the Sphenopalatine ganglion. The delivery is carried out by way of injection or topically.
US08603982B2	Medical composition A medical composition is described in which a synthetic polymer substrate and a composition mainly composed of a biopolymer directly adhere to each other due to dissolution of the surfaces thereof. The medical composition allows one to attach a biopolymer composition to a synthetic polymer substrate without the use of a toxic adhesive.
US08603972B2	Extended GLP-1 compounds The invention relates to protracted GLP-1 compounds and therapeutic uses thereof.
US08603969B2	Pancreatic polypeptide family motifs and polypeptides comprising the same The present invention relates to novel Pancreatic Polypeptide Family (“PPF”) polypeptides. The PPF polypeptides of the invention generally include at least two PPF motif, have at least 50% sequence identity to PYY (3-36) over its length and will generally retain, at least in part, a biological activity of a PP, PYY or NPY. Preferred PPF polypeptides of the invention are those having a potency in one of the assays described herein (preferably food intake, gastric emptying, pancreatic secretion, or weight reduction assays) which is greater than the potency of PP, NPY, PYY, or PYY(3-36) in that same assay. In one aspect, the PPF polypeptides of the invention include novel PYY analog polypeptides. In another aspect, the PPF polypeptides of the invention include PPF chimeric polypeptides including a fragment of a PP family polypeptide linked to a second PP family polypeptide, wherein each of the first and second fragments includes a PPF motif. Methods of using the PPF polypeptides of the invention, and pharmaceutical compositions including the PPF polypeptides of the invention are also disclosed.
US08603964B2	Methods for modulating angiogenesis via dystrophin Dp71 The present invention relates to methods and compositions for inhibiting or stimulating angiogenesis. The invention shows the implication of Dp71 in angiogenesis and thus provides novel therapeutic approaches, as well as novel methods for screening agents modulating angiogenesis, which target this protein. More specifically, the present invention relates to the use of Dp71 or a variant thereof (or a coding nucleic acid) for stimulating angiogenesis in a subject, particularly a human subject. The invention relates to the use of an inhibitor of Dp71 for inhibiting angiogenesis in a subject.
US08603963B1	Fragrance compositions containing low vapor pressure VOC solvents A fragrance composition comprising a low vapor pressure VOC and at least one low vapor pressure VOC potentiator compound, which reduces, or altogether completely obviates the use of HVPVOC solvents in fragrance compositions.
US08603962B2	Methods for treating fabric in a dryer with a composition comprising silicic acid esters Methods of treating fabric in a dryer and the fabric treatment devices used to provide the fabric treatment composition to the fabric are disclosed. More particularly, methods of treating fabric in a dryer that provides treatment of fabric, including fragrance delivery onto the fabrics, during a multiple of treatment device uses, which may be useful in laundry drying applications and may also provide effective fragrance delivery to the laundered and dried fabrics are provided herein.
US08603956B2	Super overbased polyalkenyl sulfonate and alkylaryl sulfonate composition and process for making the same The present invention is directed to super overbased polyalkenyl sulfonate and alkylaryl sulfonate composition comprising (a) one or more super overbased polyalkenyl sulfonates and (b) one or more super overbased alkylaryl sulfonates wherein the total base number (TBN) of the sulfonate composition is greater than 400. The present invention is also directed to a process for preparing such super overbased polyalkenyl sulfonate and alkylaryl sulfonate composition.
US08603955B2	Lubricant composition and antioxidant composition The lubricating oil composition of the present invention comprises at least one species of aromatic constituent selected from the following (a1) to (a5): (a1) a lubricating base oil comprising a polycyclic aromatic content of 0.01% by mass or more based on the total amount of base oil (a2) a lubricating base oil comprising a total aromatic content of 20 to 100% by mass based on the total amount of base oil (a3) an aromatic solvent (a4) at least one species of polycyclic aromatic compound selected from alkyl naphthalene and compounds having three or more aromatic rings, and (a5) an aromatic compound having a nitrogen atom, an oxygen atom or a sulfur atom; and an organic molybdenum compound.
US08603950B2	Methods of generating libraries and uses thereof This invention relates to methods for the generation of polynucleotide seed libraries and the use of these libraries in generating novel mutants of recombinant proteins and, more particularly, for generating focused libraries of recombinant human antibodies and screening for their affinity binding with target antigens.
US08603949B2	Libraries of optimized cytochrome P450 enzymes and the optimized P450 enzymes The present disclosure teaches that the recombination of homologous sequences of P450 enzymes, with the aid of SCHEMA to predict a resulting protein structure, is able to generate libraries of chimeras with significant functional diversity. Additionally, the members of these libraries demonstrate superior or unexpected new properties, which correlate with other factors that are observable in the library. Thus, the making of libraries of optimized P450 enzymes, the analysis of libraries to identify an optimized subset, and the optimized chimeras with improved or altered functionalities are all taught in the present disclosure.
US08603947B2	(4-haloalkyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides A description is given of (4-haloalkyl-3-thiobenzoyl)cyclohexanediones of the formula (I) and of their use as herbicides. In this formula (I), X, Y, R1, R2, R3, and R4 are radicals such as hydrogen and organic radicals such as alkyl. A and Z are oxygen or alkylene.
US08603934B2	Carbon nanosphere with at least one opening, method for preparing the same, carbon nanosphere-impregnated catalyst using the carbon nanosphere, and fuel cell using the catalyst A carbon nanosphere has at least one opening. The carbon nanosphere is obtained by preparing a carbon nanosphere and treating it with an acid to form the opening. The carbon nanosphere with at least one opening has higher utilization of a surface area and electrical conductivity and lower mass transfer resistance than a conventional carbon nanotube, thus allowing for higher current density and cell voltage with a smaller amount of metal catalyst per unit area of a fuel cell electrode.
US08603931B2	Method of preparing catalyst for fuel cell A method of preparing a fuel cell catalyst includes preparing a catalyst precursor solution by mixing a catalyst precursor and a solvent, and subjecting the catalyst precursor solution to radiation of electron beams having energy of less than or equal to 1 MeV. A method of preparing the fuel cell catalyst uses electron beams having low energy so that it can provide a desirable catalyst uniformly in a simple and economical process, as well as releasing few X-rays so that the catalyst can be mass produced.
US08603930B2	High-purity fused and crushed zirconia alloy powder and method of producing same The present invention provides a high-purity fused and crushed stabilized zirconia powder. The powder—with or without further processing, such as plasma spheroidization—is used in thermal spray applications of thermal barrier coatings (TBCs) and high-temperature abradables. The resulting coatings have a significantly improved high temperature sintering resistance, which will enhance the durability and thermal insulation effect of the coating.
US08603927B2	Surfactant coated fibrous nonwoven mats Coated and uncoated fibrous mats, and laminates containing the mat, having one or more surfactants on the fibers and binder holding the fibers together in only a portion of the thickness of the mat are disclosed. The mat contains a major portion of non-cellulosic fibers and a minor portion of cured resinous binder with the most typical fibers being glass fibers. The surfactant on the surface of the fibers causes a slurry or other liquid applied to the mat in a later process to form a board or laminate like faced gypsum board, a faced foam board, etc. to uniformly penetrate the mat to the desired distance. Also disclosed are methods of applying the surfactant(s) to the hot, coated or uncoated, mat soon after the coated or uncoated mat exits a drying oven used in the process of making, or coating, the mat.
US08603925B2	Leather-like sheet material, process for production thereof, and interior, clothing and industrial materials made by using the same The invention provides a leather-like sheet material which is excellent in surface appearance, texture and physical properties and considerate of the environment; a process for the production thereof; and interior, clothing, and industrial materials made by using the same. A leather-like sheet material made from a nonwoven fabric which is constituted of ultra-fine fibers having a mean single-fiber fineness of 0.001 to 0.5 dtex and impregnated with a self-emulsifiable polyurethane, wherein the self-emulsifiable polyurethane and the ultra-fine fibers do substantially not adhere closely to each other, the moieties of the polyurethane have a nonporous structure, and the polyurethane has a structure crosslinked by siloxane bond in the molecular structure.
US08603924B2	Methods of forming gate dielectric material A method of forming gate dielectric material includes forming a silicon oxide gate layer over a substrate. The silicon oxide gate layer is treated with a first ozone-containing gas. After treating the silicon oxide gate layer, a high dielectric constant (high-k) gate dielectric layer is formed over the treated silicon oxide gate layer.
US08603923B2	Dipping solution for use in production of siliceous film and process for producing siliceous film using the dipping solution This invention relates to a dipping solution used in a process for producing a siliceous film. The present invention provides a dipping solution and a siliceous film-production process employing the solution. The dipping solution enables to form a homogeneous siliceous film even in concave portions of a substrate having concave portions and convex portions. The substrate is coated with a polysilazane composition, and then dipped in the solution before fire. The dipping solution comprises hydrogen peroxide, a foam-deposit inhibitor, and a solvent.
US08603918B2	Semiconductor devices and methods of manufacture thereof Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes a workpiece having a buried layer disposed beneath a top portion thereof. A trench is disposed in the workpiece extending at least through the buried layer. At least one sinker contact is disposed in the top portion of the workpiece. The at least one sinker contact is proximate sidewalls of at least a portion of the trench and is adjacent the buried layer. An insulating material is disposed on the sidewalls of the trench. A conductive material is disposed within the trench and is coupled to a lower portion of the workpiece.
US08603917B2	Method of processing a wafer According to embodiments of the present invention, a method of processing a wafer is provided. The wafer includes a plurality of through-wafer interconnects extending from a frontside surface of the wafer to a backside surface of the wafer. The method includes removing a part of wafer material of the back-side such that a portion of the wafer material between the through-wafer interconnects is removed, thereby exposing a portion of the through-wafer interconnects, forming a layer of low-k dielectric material between the through-wafer interconnects, and planarizing the layer of low-k dielectric material such that a surface of the portion of the through-wafer interconnect is exposed.
US08603912B2	Power semiconductor component and method for the production thereof A power semiconductor component and a method for the production of a power semiconductor component are disclosed. According to one embodiment of the invention, a topmost metallization region that is provided is formed in a manner extended laterally and outside contacts formed, in such a way that, as a result, a protection and sealing material region to be provided is formed, while avoiding electrically insulating additional protection and sealing layers that are usually to be provided.
US08603911B2	Semiconductor device and fabrication method thereof A semiconductor structure includes a chip, a plurality of metal posts disposed in the chip and a buffer layer disposed on the chip. The chip includes a silicon-based layer having opposite first and second surfaces, and a build-up structure formed on the first surface of the silicon-based layer consisting of at least a metal layer and a low-k dielectric layer alternatively stacked on one another. Each of the metal posts is disposed in the silicon-based layer with one end thereof electrically connected with the metal layer while the other end is exposed from the second surface of the silicon-based layer. The buffer layer is disposed on the build-up structure. By positioning the low-k dielectric layer far from the second surface that is used for connecting to an external electronic component, the present invention reduces the overall thermal stress.
US08603908B2	Mitigation of silicide formation on wafer bevel A method for preventing formation of metal silicide material on a wafer bevel is provided, where the wafer bevel surrounds a central region of the wafer. The wafer is placed in bevel plasma processing chamber. A protective layer is deposited on the wafer bevel. The wafer is removed from the bevel plasma processing chamber. A metal layer is deposited over at least part of the central region of the wafer, wherein part of the metal layer is deposited over the protective layer. Semiconductor devices are formed while preventing metal silicide formation on the wafer bevel.
US08603906B2	Method of forming a three-dimensional semiconductor memory device comprising sub-cells, terraced structures and strapping regions Provided is a three-dimensional semiconductor memory device. The three-dimensional semiconductor memory device includes a substrate that has a cell array region including a pair of sub-cell regions and a strapping region interposed between the pair of sub-cell regions. A Plurality of sub-gates are sequentially stacked on the substrate in each of the sub-cell regions, and interconnections are electrically connected to extensions of the stacked sub-gates, respectively, which extend into the strapping region. Each of the interconnections is electrically connected to the extensions of the sub-gate which are disposed in the pair of the sub-cell regions, respectively, and which are located at the same level.
US08603905B2	Dual alignment strategy for optimizing contact layer alignment An improved method for optimizing layer registration during lithography in the fabrication of a semiconductor device is disclosed. In one example, the method comprises optimizing contact layer registration of an SRAM device having a plurality of transistors having active and gate region features extending generally along a channel length (X) direction and a channel width (Y) direction, respectively. The method comprises aligning a contact layer to a gate layer in the channel length direction (X), using gate layer overlay marks to control the alignment of the contact layer in the channel length direction (X) of the semiconductor device. The method further includes aligning the contact layer to an active layer in the channel width direction (Y), using active layer overlay marks to control the alignment of the contact layer in the channel width direction (Y) of the semiconductor device.
US08603899B2	Method of manufacturing a semiconductor device At present, a forming process of a base film through an amorphous silicon film is conducted in respective film forming chambers in order to obtain satisfactory films. When continuous formation of the base film through the amorphous silicon film is performed in a single film forming chamber with the above film formation condition, crystallization is not sufficiently attained in a crystallization process. By forming the amorphous silicon film using silane gas diluted with hydrogen, crystallization is sufficiently attained in the crystallization process even with the continuous formation of the base film through the amorphous silicon film in the single film forming chamber.
US08603896B2	Method for transferring a monocrystalline semiconductor layer onto a support substrate A method for transferring a monocrystalline semiconductor layer onto a support substrate by implanting species in a donor substrate; bonding the donor substrate to the support substrate; and fracturing the donor substrate to transfer the layer onto the support substrate; wherein a portion of the monocrystalline layer to be transferred is rendered amorphous, without disorganizing the crystal lattice of a second portion of the layer, with the portions being, respectively, a surface portion and a buried portion of the monocrystalline layer; and wherein the amorphous portion is recrystallized at a temperature below 500° C., with the crystal lattice of the second portion serving as a seed for recrystallization.
US08603895B1	Methods of forming isolation structures for semiconductor devices by performing a deposition-etch-deposition sequence In one example, the method includes forming a patterned etch mask above a semiconducting substrate, performing an etching process through the patterned etch mask to thereby form a trench in the substrate, performing a first deposition process to form a first layer of insulating material above the patterned etch mask and in the trench, and performing an etching process on the first layer of insulating material such that the post-etch thickness of the first layer of insulating material is less than an as-deposited thickness of the first layer of insulating material. The method also includes performing a second deposition process to form a second layer of insulating material on the etched first layer of insulating material, wherein the second layer of insulating material overfills the trench, and removing portions of the etched first layer of insulating material and the second layer of insulating material positioned above the patterned etch mask.
US08603893B1	Methods for fabricating FinFET integrated circuits on bulk semiconductor substrates Methods are provided for fabricating FinFET integrated circuits on bulk semiconductor substrates. In accordance with one embodiment a patterned hard mask that defines locations of a regular array of a plurality of fins is formed overlying a semiconductor substrate. Portions of the patterned hard mask are removed using a cut mask to form a modified hard mask. The substrate is etched using the modified hard mask as an etch mask to form a plurality of fins extending upwardly from the substrate and separated by trenches. Selected ones of the plurality of fins are at least partially removed to form isolation regions and an insulating material is deposited to fill the trenches and to cover the at least partially removed selected ones of the plurality of fins.
US08603891B2	Methods for forming vertical memory devices and apparatuses Methods of forming vertical memory devices include forming first trenches, at least partially filling the first trenches with a polysilicon material, and forming second trenches generally perpendicular to the first trenches. The second trenches may be formed by removing one of silicon and oxide with a first material removal act and by removing the other of silicon and oxide in a different second material removal act. Methods of forming an apparatus include forming isolation trenches, at least partially filling the isolation trenches with a polysilicon material, and forming word line trenches generally perpendicular to the isolation trenches, the word line trenches having a depth in a word line end region about equal to or greater than a depth thereof in an array region. Word lines may be formed in the word line trenches. Semiconductor devices, vertical memory devices, and apparatuses are formed by such methods.
US08603889B2	Integrated circuit structure having air-gap trench isolation and related design structure A method of forming an integrated circuit structure includes: forming a vent via extending through a shallow trench isolation (STI) and into a substrate; selectively removing an exposed portion of the substrate at a bottom of the vent via to form an opening within the substrate, wherein the opening within the substrate abuts at least one of a bottom surface or a sidewall of the STI; and sealing the vent via to form an air gap in the opening within the substrate.
US08603888B2	Variable-resistance material memories, processes of forming same, and methods of using same A variable-resistance material memory array includes a series of variable-resistance material memory cells. The series of variable-resistance material memory cells can be arranged in parallel with a corresponding series of control gates. A select gate can also be disposed in series with the variable-resistance material memory cells. Writing/reading/erasing to a given variable-resistance material memory cell can include turning off the corresponding control gate, while turning on all other control gates. Various devices can include such a variable-resistance material memory array.
US08603869B2	Method of fabricating thin film transistor having amorphous and polycrystalline silicon Provided are thin film transistor, a method of fabricating the same, a flat panel display device including the same, and a method of fabricating the flat panel display device, that are capable of applying an electric field to a gate line to form a channel region of a semiconductor layer of a thin film transistor using a polysilicon layer crystallized by a high temperature heat generated by Joule heating of a conductive layer. As a result, a process can be simplified using a gate line included in the thin film transistor as the conductive layer, and the channel region of the semiconductor layer can be formed of polysilicon having a uniform degree of crystallinity. The thin film transistor includes a straight gate line disposed in one direction, a semiconductor layer crossing the gate line, and source and drain electrodes connected to source and drain regions of the semiconductor layer.
US08603868B2	V-groove source/drain MOSFET and process for fabricating same A method includes providing a substrate containing at least first and second adjacent gate structures on a silicon surface of the substrate; etching a V-shaped groove through the silicon surface between the first and second adjacent gate structures, where the V-shaped groove extends substantially from an edge of the first gate structure to an opposing edge of the second gate structure; implanting a source/drain region into the V-shaped groove; and siliciding the implanted source/drain region. The etching step is preferably performed by using a HCl-based chemical vapor etch (CVE) that stops on a Si(111) plane of the silicon substrate (e.g., a SOI layer). A structure containing FETs that is fabricated in accordance with the method is also disclosed.
US08603863B2	Method of manufacturing card This IC card is provided with a module having an inlet, an adhesive layer covering the module, and a first base material and second base material sandwiching the module with interposition of the adhesive layer. The module is disposed on one face of the first base material with interposition of a viscous layer which has a thickness that varies according to the thickness at each area of the module, and its two ends are narrower than its other parts when viewed from the outer face side of the first base material or the outer face side of the second base material. According to this IC card, it is possible to offer the IC card with a flat surface, and without occurrence of strain in the embedded IC chip.
US08603860B2	Process for forming packages A method includes loading a first package component on a concave boat, and placing a second package component over the first package component. A load clamp is placed over the second package component, wherein the load clamp is supported by a temperature-variable spacer of the concave boat. A reflow step is performed to bond the second package component to the first package component. During a temperature-elevation step of the reflow step, the temperature-variable spacer is softened in response to an increase in temperature, and a height of the softened temperature-variable spacer is reduced, until the load clamp is stopped by a rigid spacer of the concave boat.
US08603858B2	Method for manufacturing a semiconductor package A method for manufacturing a semiconductor package, the method comprising providing a substrate having opposite first and second surfaces and having one or more through openings formed therethrough from the first to the second surfaces at predefined positions; providing at least one first die having first and second opposite surfaces and having one or more first contact terminals on the first surface of the at least one first die; placing the at least one first die with the first surface thereof on the first surface of the substrate, with an adhesive applied therebetween outside the one or more through openings, such that the one or more through openings are aligned to the one or more first contact terminals, whereby a die assembly having correspondingly opposite first and second surfaces is formed; providing the first surface of the die assembly with a first plating layer of an electrically conductive plating material to electrically contact the one or more first contact terminals, wherein the plating material of the first plating layer extends in the through openings to electrically contact the one or more first contact terminals therethrough.
US08603854B2	Preparation method for resistance switchable conductive filler for ReRAM Disclosed are methods for preparing a resistive random-access memory (ReRAM) based on resistive switching using a resistance-switchable conductive filler. When a resistance-switchable conductive filler prepared by coating a conductive filler with a material whose resistance is changeable is mixed with a dielectric material, the dielectric material is given the resistive switching characteristics without losing its inherent properties. Therefore, various resistance-switchable materials having various properties can be prepared by mixing the resistance-switchable conductive filler with different dielectric materials. The resulting resistance-switchable material shows resistive switching characteristics comparable to those of the existing metal oxide film-based resistance-switchable materials. Accordingly, a ReRAM device having the inherent properties of a dielectric material can be prepared using the resistance-switchable conductive filler.
US08603848B2	Three-dimensional MEMS structure and method of manufacturing the same Provided are a three-dimensional (3D) MEMS structure and a method of manufacturing the same. The method of manufacturing the 3D MEMS structure having a floating structure includes depositing a first etch mask on a substrate, etching at least two regions of the first etch mask to expose the substrate, and forming at least one step in the etched region, partially etching the exposed region of the substrate using the first etch mask, and forming at least two grooves, depositing a second etch mask on a sidewall of the groove, and performing an etching process to connect lower regions of the at least two grooves to each other, and forming at least one floating structure.
US08603844B2	Pixel structure and manufacturing method thereof A method for manufacturing a pixel structure is provided. A thin film transistor is formed on a substrate and an insulating layer is formed to cover the substrate and the thin film transistor. The insulating layer is patterned by a half-tone mask to form a protruding pattern, a sunken pattern connecting the protruding pattern, and a contact window inside the sunken pattern. A transparent conductive layer is formed to cover the protruding pattern and the sunken pattern, and filled in the contact window. A passivation layer is formed to cover the transparent conductive layer. A pixel electrode pattern is formed from the transparent conductive layer by removing a part of the passivation layer located on the protruding pattern, a part of the transparent conductive layer on the protruding pattern, and a part of the passivation layer located within the contact window. A pixel structure manufactured by the method is provided.
US08603841B2	Manufacturing methods of semiconductor device and light-emitting display device An object is to simplify a manufacturing process of a transistor, and to manufacture a light-emitting display device not only with a smaller number of photomasks compared to the number of photomasks used in the conventional method but also without an additional step. By using an intrinsic or substantially intrinsic high-resistance oxide semiconductor for a semiconductor layer included in the transistor, so that a step of processing the semiconductor layer into an island shape in each transistor can be omitted. Unnecessary portions of the semiconductor layer are etched away at the same time as a step of forming an opening in an insulating layer formed in an upper layer of the semiconductor layer, so that the number of photolithography steps is reduced.
US08603832B2	Lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region.
US08603831B2	Method of determining a composition of fuel in a power station A method and a device for monitoring the combustion of fuel in a power station are provided. An actual concentration distribution of a material in a combustion chamber is measured, the actual concentration distribution is evaluated, taking into consideration a combustion stochiometry, and conclusions are drawn regarding a composition of the fuel on the basis of the evaluation that has been carried out.
US08603827B2	Tracer materials A tracer system comprising a tracer compound for a fluid system, the tracer compound comprising one or more polyether alcohol compounds. The one or more polyether alcohol compounds is arranged for being placed in contact with a first part of said fluid system. The one or more polyether alcohol compounds is truly monodisperse. The polyether alcohol compounds comprises one or more functional groups. The one or more truly monodisperse polyether alcohol compounds is arranged for being detected in a second part of the fluid system in fluid communication with said first part of said fluid system. The tracer compound is detectable in very low concentrations.
US08603822B2	Method for designing heat-resistant tyrosine-dependent short-chain dehydrogenase/reductase and heat-resistant tyrosine-dependent short-chain dehydrogenase/reductase A method for designing a heat-resistant mutant enzyme, the method including the step of reducing a distance between the α4 helix and the α6 helix in a protein three-dimensional structure to become smaller than that of a wild type enzyme through deletion, replacement, addition, or insertion of one or several amino acids in the amino acid sequence of the wild type enzyme with respect to tyrosine-dependent short-chain dehydrogenase/reductase.
US08603818B1	TGF-beta receptor inhibitors to enhance direct reprogramming In general, iPS cells are produced by delivery of stem cell-associated genes into adult somatic cells (e.g., fibroblasts). Described herein are methods for enhancing the efficiency and rate of induced pluripotent stem cell production by treating somatic cells with a transforming growth factor-beta receptor (TGFβR) inhibitor. Also described herein are iPS cell compositions made according to the methods described herein and iPS cell compositions comprising an iPS cell in an admixture with a TGFβR inhibitor. Further described herein are kits for producing iPS cells using a TGFβR inhibitor.
US08603815B2	CD4+ CD25− T cells and Tr1-like regulatory T cells The invention provides CD4+CD25− T cells and Tr1-like regulatory T cells (i.e., contact-independent Type 1-like regulatory T cells), processes for their production and their use for regulatory purposes.
US08603813B2	Cells useful for immuno-based botulinum toxin serotype A activity assays The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
US08603812B2	Cells useful for immuno-based botulinum toxin serotype A activity assays The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
US08603805B2	Gas spargers and related container systems A sparger includes a body bounding a compartment. A tubular port or tube is coupled with the body. The tubular port or tub bounds a passage that communicates with the compartment of the body. At least a portion of the body includes of a first sparging sheet. The first sparging sheet includes a flexible sheet of a gas permeable material such that a gas passing into the compartment of the body through the passage can exit the compartment by permeating through the first sparging sheet.
US08603801B1	Method of processing stillage A method for processing of byproducts in an ethanol production process is provided. The method includes applying a mixture of a microorganism to a stillage stream, metabolizing gums in the stillage stream using the mixture to release oil in the gums carried by the stillage stream and recovering the oil. Methods of liberating or releasing bound oil present in stillage are also provided.
US08603800B2	Production of acetyl-coenzyme A derived isoprenoids Provided herein are compositions and methods for the heterologous production of acetyl-CoA-derived isoprenoids in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an acetaldehyde dehydrogenase, acetylating (ADA, E.C. 1.2.1.10) and an MEV pathway comprising an NADH-using HMG-CoA reductase. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an ADA and an MEV pathway comprising an acetoacetyl-CoA synthase. In some embodiments, the genetically modified host cell further comprises one or more heterologous nucleotide sequences encoding a phosphoketolase and a phosphotransacetylase. In some embodiments, the genetically modified host cell further comprises a functional disruption of the native PDH-bypass. The compositions and methods described herein provide an energy-efficient yet redox balanced route for the heterologous production of acetyl-CoA-derived isoprenoids.
US08603799B2	Growth enhancement and control of bacterial and fungal plant diseases with Streptomyces scopuliridis Methods of controlling plant diseases mediated by bacterial or fungal plant pathogens. The method comprises providing Streptomyces scopuliridis strain RB72 or an isolated protein or polypeptide comprising the amino acid of SEQ ID NO:1 and applying the Streptomyces scopuliridis strain RB72 or the isolated protein or polypeptide comprising the amino acid of SEQ ID NO:1 to plants or plant seeds under conditions effective to treat plant diseases mediated by bacterial or fungal plant pathogens. Also disclosed is a plant or plant seed treated by this method, a planting composition, and a method of enhancing growth.
US08603796B2	Method for producing storage stable viruses and immunogenic compositions thereof The invention relates to methods for producing storage stable virus compositions. In certain embodiments, the invention relates to one or more formulations and process steps which result in storage stable virus compositions, wherein the composition is storage stable as a lyophilized solid composition or a frozen liquid composition.
US08603794B2	Polypeptides having cellobiohydrolase 1 activity and polynucleotides encoding same The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
US08603791B2	Nucleic acid sample preparation The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
US08603785B2	Method of organic polymer degradation by dihydrolipoamide dehydrogenase A dihydrolipoamide dehydrogenase (DLD) in a germ is recombined. The new DLD is applied in a solution to degrade an ether bond of an organic polymer. With the present invention, bioremediation is accomplished without secondary pollution of compounds which have environmental hormones.
US08603784B2	Infectious clone of human parvovirus B19 and methods The invention relates to infectious clones of parvovirus B19, methods of cloning infectious B19 clones, and methods of cloning viral genomes that have secondary DNA structures that are unstable in bacterial cells. A B19 infectious clone and methods of producing B19 infectious clones are useful for producing infectious virus. Infectious virus is useful for identifying and developing therapeutically effective compositions for treatment and/or prevention of human parvovirus B19 infections.
US08603782B2	Heat lysis production of proteins The present invention provides methods of producing isolated heat stable polypeptides by expressing the polypeptides in a prokaryotic host cell and subjecting the host cell to heat lysis. The invention further provides screening methods by producing a plurality of isolated heat stable polypeptides by expressing each of the plurality of polypeptides in a prokaryotic host cell and subjecting the host to heat lysis.
US08603781B2	Prevention of incorporation of non-standard amino acids into protein The instant invention is drawn to the methods and compositions necessary to provide recombinant proteins with a substantially reduced or eliminated content of norleucine or other non-standard amino acids. Various embodiments of the invention provide for the substantial elimination of the incorporation of non-standard amino acids into recombinant proteins by the co-expression or enhanced expression of a protein (or the enzymatically active portion thereof) capable of degrading norleucine or other non-standard amino acids, including norvaline, beta-methylnorleucine, and homoisoleucine. In certain particular embodiments of the invention, the norleucine is degraded by a glutamate dehydrogenase, a leucine dehydrogenase, a valine dehydrogenase, a phenylalanine dehydrogenase, a glutamate/leucine/phenylalanine/valine dehydrogenase, or an opine dehydrogenase. Also provided are the cells and DNA constructs for carrying out these methods.
US08603780B2	Methods and compositions for enhanced expression and secretion of proteins Optimized signal peptide coding sequences for enhanced expression and secretion of protein from a cell and related compositions and methods are described. The optimized signal peptide coding sequence encodes an mRNA that contains at least one hairpin structure immediately downstream of the initiation codon. Methods for obtaining the optimized signal peptide coding sequences and methods for enhanced expression and secretion of proteins using the optimized signal peptide coding sequences are also described.
US08603779B2	Non-cytotoxic protein conjugates The present invention is directed to non-cytotoxic protein conjugates for inhibition or reduction of exocytic fusion in a nociceptive sensory afferent cell. The protein conjugates comprise: (i) a galanin Targeting Moiety (TM), wherein the TM is an agonist of a receptor present on a nociceptive sensory afferent cell, and wherein the receptor undergoes endocytosis to be incorporated into an endosome within the nociceptive sensory afferent cell; (ii) a non-cytotoxic protease or a fragment thereof, wherein the protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of the nociceptive sensory afferent cell; and (iii) a Translocation Domain, wherein the Translocation Domain translocates the protease or protease fragment from within the endosome, across the endosomal membrane, and into the cytosol of the nociceptive sensory afferent cell. Nucleic acid sequences encoding the protein conjugates, methods of preparing same and uses thereof are is also described.
US08603778B2	Anti-TNF antibodies, compositions, methods and uses The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS:1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.
US08603777B1	Expression of factor VII and IX activities in mammalian cells Methods are disclosed for producing proteins having biological activity for blood coagulation mediated by Factor VIIa or Factor IX. The proteins are produced by mammalian host cells which have been stably transfected with a DNA construct containing a nucleotide sequence which codes at least partially for either Factor VII or Factor IX. The nucleotide sequence comprises a first nucleotide sequence encoding a calcium binding domain, joined to a second nucleotide sequence positioned downstream of the first sequence. The second sequence encodes a catalytic domain for the serine protease activity of either Factor VIIa or Factor IX. The joined sequences code for proteins having substantially the same biological activity for blood coagulation as either Factor VIIa or Factor IX.
US08603776B2	Method for preparing xylose-utilizing strain A method for preparing a xylose-utilizing strain of Saccharomyces cerevisiae and the Saccharomyces cerevisiae are introduced. The preferred recombinant strain contains multiple copies of integrated xylose metabolic genes, and can rapidly ferment xylose to produce ethanol from synthetic medium and lignocellulosic raw materials. The xylose-utilizing strain is applicable for the cellulosic ethanol production industry and brewing industry.
US08603768B2	System and method for measuring an analyte in a sample Methods of determining a corrected analyte concentration in view of some error source are provided herein. The methods can be utilized for the determination of various analytes and/or various sources of error. In one example, the method can be configured to determine a corrected glucose concentration in view of an extreme level of hematocrit found within the sample. In other embodiments, methods are provided for identifying various system errors and/or defects. For example, such errors can include partial-fill or double-fill situations, high track resistance, and/or sample leakage. Systems are also provided for determining a corrected analyte concentration and/or detecting some system error.
US08603767B2	Luciferase-based assays A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent.
US08603766B2	Monitoring and inhibiting human immunodeficiency virus infection by modulating HMGB1 dependent triggering of HIV-1 replication and persistence Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural killer (NK) cells. Therapeutic compositions comprising antibodies and drugs, such as glycyrrhizin, which bind to HMGB1. Methods of detecting or monitoring HIV infection involving detection or quantitation of HMGB1 or antibodies specific for HMGB1 in a biological sample.
US08603765B2	Immunoassay reagents and methods of use thereof The present invention provide reagents and methods of using the reagents, for example, on automated staining devices, that facilitate detection of two or more antigens in a sample simply and efficiently.
US08603764B2	EphA kinase cancer diagnostic A method of detecting malignant progression of neoplastic cells in an animal includes obtaining a sample of neoplastic cells from the animal, determining a level of S897-EphA2 phosphorylation in the neoplastic cells of the samplem, and comparing the determined level of S897-EphA2 phosphorylation in the sample to a control value, wherein an increased level of S897-EphA2 phosphorylation compared to the control value is indicative of malignant progression of the neoplastic cell in the animal.
US08603759B2	Recombinant protein capable of binding specifically and quickly to troponin I derived from human myocardium Provided is a recombination protein which binds specifically to troponin I derived from human myocardium. The recombinant protein includes a light chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 63; and a heavy chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 65.
US08603757B2	Methods of screening T1R1/T1R3 heteromeric receptors for compounds that modulate umami taste signaling The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners.Also the present invention relates to the use of hetero-oligomeric taste receptors comprising T1R1/T1R3 and T1R2/T1R3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli.
US08603756B2	Antigen surrogates in autoimmune disease The present invention provides for the identification of an antigen surrogate to the native antigens for the autoimmune disease pemphigus vulgaris. Ligands are discovered using large random peptoid or cyclic peptoid libraries that are screened against known antibodies to autoimmune diseases. The ligands may be useful as drugs in the treatment of such diseases and can also be used in combination with the concomitant removal of T-cells associated with autoimmune disorders.
US08603755B2	Resistance to auxinic herbicides The invention provides methods of identifying herbicidal auxins. The invention further provides auxin-herbicide-resistant plants and genes conferring auxin-herbicide resistance. This invention also provides a method of identifying other proteins that bind picolinate auxins from additional plant species. The invention further provides a method to identify the molecular binding site for picolinate auxins. The invention also includes the use of the picolinate herbicidal auxin target site proteins, and methods of discovering new compounds with herbicidal or plant growth regulatory activity. The invention also includes methods for producing plants that are resistant to picolinate herbicidal auxins. Specific examples of novel proteins associated with herbicide binding include AFB5, AFB4, and SGT1b.
US08603751B2	Mycobacterial disease detection, treatment, and drug discovery Methods for detecting and treating Mycobacterium-related diseases including reducing Mycobacterial virulence, reducing RV3133c dimerization, and treating a subject with a Mycobacterial infection using identified compounds are disclosed. Examples of compounds useful in the treatment of Mycobacterium-related diseases include N-(4-[(acetylamino)sulfonyl]phenyl)-3-phenylpropanamide; 1-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-(2-imino-3-methyl-2,3-dihydro-1H-benzimidazol-1yl)ethanone hydrochloride; and 1-(1,3-benzoxazol-2-yl)-3-({4-[(2-hydroxyethyl)sulfonyl]phenyl}amino)acrylaldehyde. Further disclosed are methods for identifying agents that interact with a polypeptide in a Mycobacterium cell.
US08603749B2	Multitag sequencing ecogenomics analysis-US Embodiments of the invention herein described relate to multiplex polynucleotide sequence analysis without the use of size separation methods or blotting. In certain particulars the invention relates to multiplex sequencing using massively parallel sequencing methods, such as pyrosequencing methods and sequencing by synthesis. The invention provides increased throughput, increased accuracy of enumerating sample components, and the ability to analyze greater numbers of samples simultaneously or serially on presently available systems, as well as others yet to be developed. In certain of its embodiments the invention relates to the analysis of complex microbial communities, particularly to in-depth analysis thereof in large numbers of samples.
US08603748B2	Genetic methods for speciating Campylobacter The phylogeny of twelve Campylobacter species was determined based on partial (1020-bp) gyrB gene sequences. Methods have been described for detection and speciation of Campylobacter, including 16S rRNA sequence analysis. However, gyrB provides a better resolution than the 16S rDNA gene for Campylobacter species with interspecies sequence similarities ranging from 58.3 to 89.2% compared to those reported for the 16S rRNA gene (ranging from 89 to 99%). A universal primer set, designed to amplify a 960-bp fragment of the gyrB gene in Campylobacter spp., was developed and used for (PCR-RFLP) of 19 strains representing twelve Campylobacter species and resulted in unique digest patterns for all twelve Campylobacter species. PCR assays for amplification of regions of the gyrB gene specific for each Campylobacter species were also developed. Using these PCR and PCR-RFLP methods results in unambiguous identification of the majority of Campylobacter species.
US08603739B2	Inhibitors of Rv0256c Described herein are methods for identifying inhibitors of Rv0256c functions, e.g., inhibitors of Rv0256c expression, DNA binding, nuclear localization and iNOS inhibition.
US08603736B2	Compositions and methods for determining resistance to inhibitors of virus entry using recombinant virus assays The invention provides a method for determining whether a human immunodeficiency virus is resistance to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor.
US08603734B2	Biomarkers for prostate cancer The instant invention provides methods and compositions for the detection of prostate cancer is a subject. In one embodiment, a method of detecting prostate cancer in a subject comprises the steps of (a) detecting the presence of at least one biomarker listed in Table 1 in a serum sample, wherein the presence of the biomarker in the serum sample is indicative of prostate cancer.
US08603725B2	Laser-engraveable compositions and flexographic printing precursors Flexographic printing precursors are prepared using laser-engraveable compositions containing a laser-engraveable resin and chemically-crosslinked organic porous particles. The presence of these porous particles, which can include an infrared radiation absorber, improves various imaging and performance properties in the preparation of flexographic printing members such as flexographic printing plates and printing sleeves.
US08603724B2	Negative resist composition and patterning process There is disclosed a negative resist composition comprising at least: (A) a base polymer that is alkaline-soluble and is made alkaline-insoluble by action of an acid; (B) an acid generator; and (C) a basic component, wherein the base polymer at least contains a polymer including repeating units represented by the following general formula (1) and general formula (2) and having a weight average molecular weight of 1,000 to 10,000. There can be a negative resist composition hardly causing a bridge in forming a pattern and providing a high resolution and a patterning process using the same.
US08603720B2	Toner compositions and processes A process for preparing a toner includes forming an emulsion with a buffer solution and an amorphous biodegradable polyester resin represented by Formula (1): wherein each n independently represents an integer of 1 to about 20 and x and y represent respective ratios of respective monomeric units and x ranges from about 0 to about 1000 and y ranges from about 0 to about 300; adding a colorant, a coagulant, and optionally a wax to the emulsion to form a mixture; heating the mixture, permitting aggregation and coalescence of the mixture to form toner particles; and recovering the toner particles.
US08603719B2	Method for producing electrophotographic toner, electrophotographic toner, full-color image forming method and full-color image forming apparatus A method for producing an electrophotographic toner including forming a toner base particle by emulsifying or dispersing a solution or dispersion of a toner material comprising a colorant, and any one of a binder resin and a binder resin precursor in an aqueous medium, and adding crystalline organic fine particles having an acid value of 20 mgKOH/g to 80 mgKOH/g into the aqueous medium, before, during or after the forming so as to attach the crystalline organic fine particles onto a surface of the toner base particle.
US08603716B2	Electrostatic image developing carrier, electrostatic image developer, process cartridge, image forming method and image forming apparatus An electrostatic image developing carrier includes a ferrite particle and a resin layer that coats the ferrite particle, wherein a magnesium element content of the ferrite particle is from about 3.0% by weight to about 20.0% by weight; wherein a manganese element content of the ferrite particle is from about 0.2% by weight to about 0.8% by weight; and wherein a content of toluene is more than about 100 ppm and not more than about 2,000 ppm.
US08603712B2	Toner Provided is a toner comprising a toner particle having a core-shell structure in which a shell phase containing a resin A is formed on a core that contains a binder resin, a colorant and a wax, wherein the resin A is a vinyl resin prepared by copolymerizing a vinyl monomer X that has an organopolysiloxane structure and a vinyl monomer Y that has a polyester segment capable of forming a crystalline structure; the content of the vinyl monomer X in a total monomer used for the copolymerization is in a particular range; the toner particle contains resin A in a particular proportion; and the binder resin contains a crystalline resin.
US08603711B2	Pigment dispersion and yellow toner To obtain a pigment dispersion and a yellow toner having high coloring power and high dispersibility of a pigment in a dispersion medium, a pigment dispersion containing a compound represented by general formula (1) and a yellow pigment represented by general formula (2) are provided in a dispersion medium.
US08603710B2	Alternate anticurl back coating formulation The presently disclosed embodiments related generally to a layer that provides overall flatness to flexible imaging members and components for use in electrostatographic apparatuses. More particularly, the embodiments pertain to a flexible electrophotographic imaging member belt prepared to include an anti-curl back coating formulated to comprise a mechanically robust copolymer binder that does have enhanced wear resistance and improved imaging member curl control.
US08603707B2	Exposure method and exposure mask According to one embodiment, an exposure method comprises exposing a desired pattern on a sample by use of a first reflection type mask on which the desired pattern to be exposed on the sample is formed and a defect is partially formed, and exposing a correction pattern on the sample by use of a second reflection type mask having the correction pattern of a reflection film formed at a position corresponding to the defect of the first reflection type mask.
US08603706B2	Forming a bridging feature using chromeless phase-shift lithography First and second anchor features are formed on a substrate via a chromeless photolithography process. An elongated bridging feature is formed between the anchor features on the substrate via the chromeless photolithography process. A distance between the anchor features is sufficient to minimize lateral displacement at a center portion of the bridging feature without significant reduction in mechanical stability of the bridging feature.
US08603703B2	Method for making super-hydrophilic and electrically conducting surfaces for fuel cell bipolar plates A method for embedding a hydrophilic and electrically conductive layer into a flow field plate or bipolar plate for a fuel cell. In one embodiment, the layer is niobium doped titanium oxide in a powder form. The method includes mixing the powder material in a suitable solution, such as a solvent. The solution is deposited on a substrate, such as a stainless steel substrate, by any suitable process, such as brushing. The substrate is then heated so that the solvent evaporates to leave a coating of the powder material. The substrate is then positioned in a die press and is stamped to the shape of the bipolar plate, where the stamping operation embeds the powder material into an outer surface of the bipolar plate.
US08603702B2	Zinc air fuel cell with enhanced cell performance Provided is a zinc air fuel cell with enhanced cell performance which includes a separator-electrode assembly including a perforated metal plate as a cathode current collector, a catalyst-coated carbon paper, a separator, a perforated metal plate as an anode current collector, and a tilted nonconductive support. A metal plate may be placed on the tilted nonconductive support and connected to the anode current collector in the separator-electrode assembly to enlarge the active area of the anode current collector. Performance may be efficiently enhanced by minimizing a distance between the anode current collector and the cathode current collector, and by adding a metal plate which plays a role of an additional anode current collector on the tilted nonconductive support so as to increase the overall active area of anode current collector contacting with zinc pellets and to resultantly enhance the ionization of zinc.
US08603701B2	Sheared edge on fuel cell components for wicking of water A fuel cell component including a body disposed along a plane and having a boundary past which a reactant and water flows is provided. The boundary has a discontinuous edge adapted to militate against a pinning of the water at the edge. The fuel cell component may be a bipolar plate having a port hole with the discontinuous edge. The fuel cell component may be a subgasket for a fuel cell having a boundary with the discontinuous edge. The discontinuous edge facilitates a transportation of water from an upper surface of the fuel cell component to a lower surface of the fuel cell component.
US08603698B2	Electrolyte for fuel cell, electrolyte membrane for fuel cell, binder for fuel cell, membrane electrode assembly for fuel cell, and fuel cell Disclosed is an electrolyte for fuel cells, which is mainly composed of a copolycondensate of a polyimide having an alkoxysilyl group at an end and an alkoxysilane having an ion-conducting group. Also disclosed are an electrolyte membrane for fuel cells, a binder for fuel cells and a membrane electrode assembly for fuel cells, each using the electrolyte, and a fuel cell using such a membrane electrode assembly for fuel cells. The electrolyte enables to obtain an electrolyte membrane, a binder and a membrane electrode assembly, each having high ion conductivity, high strength, high toughness, low swelling and low fuel permeability suitable for fuel cells. By using such an electrolyte, there can be obtained a low-cost fuel cell having high output power and high durability.
US08603694B2	Method for operating fuel cells for systems that are restricted by exposure to thermal stress and fuel cell stack for carrying out said method According to the invention, a fuel cell is operated at a working temperature of between 60° C. and 110° C. and thermally insulated from the exterior, the waste air from the cathode being cooled by a surplus of incoming air that is provided for the reaction. The supplied fuel is pre-heated during the exchange of heat. The fuel cell that is operated according to said method can be used in systems that are restricted by exposure to thermal stress and can be produced in a cost-effective manner.
US08603693B2	Output limiting device for fuel cell An output limiting device for a fuel cell, including: an inlet coolant temperature sensor detecting an inlet coolant temperature at a coolant inlet of the fuel cell; an outlet coolant temperature sensor detecting an outlet coolant temperature at a coolant outlet of the fuel cell; and an output limiter limiting power or current extracted from the fuel cell according to the detected inlet coolant temperature and the detected outlet coolant temperature.
US08603690B2	Methods and controls for hydrogen to cathode inlet of a fuel cell system A system and method for quickly heating a fuel cell stack at fuel cell system start-up. The fuel cell system includes a three-way valve positioned in the anode exhaust that selectively directs the anode exhaust gases to the cathode input of the fuel cell stack so that hydrogen in the anode exhaust gas can be used to heat the fuel cell stack. During normal operation when the fuel cell stack is at the desired temperature, the three-way valve in the anode exhaust can be used to bleed nitrogen to the cathode exhaust.
US08603687B2	Fuel cell system In order to assure drive of a drive motor, a boost operation of a boost device is appropriately performed by judging whether a voltage supplied from a fuel cell suffices a voltage required for driving the drive motor, thereby suppressing a switching loss by the boost device. A fuel cell system is a power source for driving a load. The system includes: a drive motor driven by an electric power; a fuel cell which generates electricity by an electrochemical reaction between an oxidizing gas containing oxygen and a fuel gas containing hydrogen and supplies an electric power to the drive motor; a first boost device which can boosts the voltage outputted from the fuel cell and supplies the boosted voltage to the drive motor; and boost control means which controls voltage boost performed by the first boost device according to the relationship between the fuel cell output voltage and the voltage required by the drive motor.
US08603684B2	Fuel cells The present invention concerns a fuel cell comprising a cathode in a cathode region of the cell and an anode in an anode region of the cell, the cathode being separated from the anode by an ion selective polymer electrolyte membrane, the cathode region of the cell being supplied in use thereof with an oxidant and a liquid low molecular weight fuel wherein at least some of the liquid low molecular weight fuel in use crosses the polymer electrolyte membrane to supply the anode region of the cell with liquid low molecular weight fuel, the cell being provided with means for generating an electrical circuit between the cathode and the anode.
US08603683B2	Gas phase deposition of battery separators In certain embodiments, a battery component comprises an electrode and a separator deposited on a surface of the electrode is provided. The separator comprises a porous poly(para-xylylene) film. In some embodiments, the electrode can include at least one cavity or protrusion, and the separator layer can be gas phase deposited directly on the electrode. In certain embodiments, methods of making a battery component are also provided.
US08603681B2	Porous film material comprising at least one carbonaceous semimetal oxide phase, and use thereof as a separator material for electrochemical cells The present invention relates to a novel porous film material which comprises at least one carbonaceous semimetal oxide phase, and to a process for production thereof. The invention also relates to the use of these porous film materials as a separator layer or for production of such separator layers in electrochemical cells, particularly in lithium cells and especially in lithium secondary cells.The inventive porous film material comprises: a) at least one carbonaceous (semi)metal oxide phase A of silicon, of aluminum, of titanium or of zirconium, which has hydrocarbon groups bonded covalently to the (semi)metal of said (semi)metal oxide phase A; b) optionally one or more organic polymer phases B, said carbonaceous (semi)metal oxide phase A forming essentially continuous phase domains in which the pore phase present in the film material and the optionally present organic polymer phase(s) B are intercalated, the mean distance between two phase boundaries of adjacent domains of identical phases being not more than 50 nm, preferably not more than 10 nm, particularly not more than 5 nm and especially not more than 2 nm.
US08603680B2	Electrode protection in both aqueous and non-aqueous electrochemical cells, including rechargeable lithium batteries Electrode protection in electrochemical cells, and more specifically, electrode protection in both aqueous and non-aqueous electrochemical cells, including rechargeable lithium batteries, are presented. In one embodiment, an electrochemical cell includes an anode comprising lithium and a multi-layered structure positioned between the anode and an electrolyte of the cell. A multi-layered structure can include at least a first single-ion conductive material layer (e.g., a lithiated metal layer), and at least a first polymeric layer positioned between the anode and the single-ion conductive material. The invention also can provide an electrode stabilization layer positioned within the electrode to control depletion and re-plating of electrode material upon charge and discharge of a battery. Advantageously, electrochemical cells described herein are not only compatible with environments that are typically unsuitable for lithium, but the cells may be also capable of displaying long cycle life, high lithium cycling efficiency, and high energy density.
US08603674B2	Composition for electrode of nonaqueous electrolyte secondary battery, electrode for nonaqueous electrolyte secondary battery using the same and nonaqueous electrolyte secondary battery A composition for an electrode of a nonaqueous electrolyte secondary battery contains an active material and a binder resin. The composition contains a vinylpyrrolidone-based polymer as the binder resin. The hydroxyl group equivalent of the vinylpyrrolidone-based polymer is within the range of 250 to 2500.
US08603666B2	Power supply apparatus A power supply apparatus that can achieve preferable holding and fixing of components constituting the power supply apparatus and can preferably prevent a liquid short-circuit and a leakage of current due to condensed water. The power supply apparatus includes a power supply unit having a plurality of power supply elements stacked with each other, an upper case and a lower case which house the power supply unit. The power supply further includes an auxiliary fastening portion which is fixed to the lower case and provides a space S between a lower surface of the power supply unit and the lower case, and fastening portions that are placed on the left and right of the power supply unit when viewed in a direction in which the power supply elements are stacked. The fastening portions fastening the power supply unit to the upper case.
US08603665B2	Battery pack of improved stability Disclosed herein is a battery pack wherein a rectangular battery having an electrode assembly and an electrolyte contained therein in a sealed state is received in a pack case, and an insulating material is filled in a space defined between the inner surface of the upper end of the pack case and the upper end of the battery, whereby the battery pack is manufactured with a reduced thickness, the assembly process of the battery pack is very simple, and short circuit of the battery pack or suspension of power supply from the battery pack, which may occur as the battery is moved, is effectively prevented even when the battery pack falls down or external impacts are applied to the battery pack.
US08603664B2	Assembled battery with stacked metal plate connection member An assembled battery is provided which can improve output density. Four unit cells are connected in series by a connection member 40 composed of a stacked metal plate obtained by stacking two metal plates 40a and 40b. The metal plate 40a is one of copper and aluminum while the metal plate 40b is nickel. Since the volume electrical resistance of both copper and aluminum is less than half that of nickel, the overall electrical resistance of the connection member 40 is lowered. Both end portions of the connection member 40 are joined to external electrode terminals by resistance welding so that the weld joint is formed from either a Cu—Ni or Al—Ni low resistance binary alloy.
US08603660B2	Battery system with heat exchanger A battery module includes a plurality of electrochemical cells arranged in a first row and a second row offset from the first row. The battery module also includes a heat exchanger configured to allow a fluid to flow through the heat exchanger. The heat exchanger is disposed between the first and second rows of cells and has a shape that is complementary to the cells in the first and second rows of cells so that an external surface of the heat exchanger contacts a portion of each of the plurality of electrochemical cells. The heat exchanger is configured to route the fluid between an inlet and an outlet such that a path of the fluid flow includes a plurality of adjacent fluid flow segments.
US08603654B2	Supplemental coolant heating for fuel cells with metal plates A fuel cell stack that includes catalyzed surfaces in the non-active inlet region of the cathode flow channels. At cold system start-up, hydrogen is introduced into the cathode inlet header to be mixed with air so that a chemical reaction is provided by the catalyst that generates heat to warm the cooling fluid in the non-active inlet area. Therefore, the cooling fluid that enters the active area of the stack will not be cold enough to quench the chemical reaction.
US08603649B2	Perpendicular magnetic recording medium A perpendicular magnetic recording medium includes a magnetic recording layer 22 having a granular structure composed of crystal grains containing cobalt (Co) and grown in a columnar shape and a grain boundary portion comprising a nonmagnetic substance and formed between the crystal grains, and a continuous layer 24 of a thin film magnetically continuous in a film plane direction. The continuous layer 24 includes a plurality of layers 24a and 24b containing cobalt, chromium (Cr), and platinum (Pt). Among the layers, the layer 24a nearer to the magnetic recording layer has a greater chromium content.
US08603648B2	Reflective film laminate A reflective film laminate is provided with high productivity and at low cost in which a protective film with minimized pinholes is provided to improve the alkali resistance and warm water resistance of the reflective film laminate including a pure Al film or an Al-based alloy film so that a reflectivity reduction resulting from the elution or oxidization of the Al film in an alkaline or warm water environment is less likely to occur. The reflective film laminate of the present invention includes, over a substrate, a pure Al film or an Al-based alloy film as a first layer, and an oxide film of a metal containing one or more elements selected from the group consisting of Zr, Cr, Y, Nb, Hf, Ta, W, Ti, Si, and Mo as a second layer over the first layer. The thickness of the second layer is 0.1 to 10 nm.
US08603646B2	Pyrrole compound and organic photoelectric device including the same A pyrrole compound for an organic photoelectric device and an organic photoelectric device including the same, the pyrrole compound being represented by the following General Formula 1:
US08603645B2	Stable and efficient electroluminescent materials An organic light emitting device is provided. The device has an anode, a cathode, and an emissive layer disposed between the anode and the cathode. The emissive layer may include a molecule of Formula I wherein an alkyl substituent at position R′5 results in high efficiency and operational stability in the organic light emitting device. Additionally or alternatively, the emissive layer may include a metal-ligand complex in which the ligand is an aryl or alkyl substituted phenylpyridine ligand.
US08603644B2	Anthracene derivative, and light-emitting material, light-emitting element, light-emitting device, and electronic device using the same Novel anthracene derivatives, novel materials capable of blue light emission with high color purity, and a light-emitting element, a light-emitting device, and an electronic device using any of the novel materials. The anthracene derivative represented by general formula (1) is provided. With the anthracene derivative, a light-emitting element with high emission efficiency can be provided. With the anthracene derivative, a light-emitting element emitting blue light with high color purity can be provided. In the formula, A1 represents a substituted or unsubstituted phenyl group, B1 represents any of an alkyl group having 1 to 4 carbon atoms or a substituted or unsubstituted phenyl group, α represents any of a substituted or unsubstituted phenylene group or a substituted or unsubstituted biphenyl-4,4′-diyl group, and R1 to R9 individually represent any of hydrogen, an alkyl group having 1 to 4 carbon atoms, or a substituted or unsubstituted phenyl group.
US08603638B2	Sealing members, articles using the same and methods of reducing sticktion The present invention provides rubber sealing members having an exterior surface adapted to sealingly engage an inner surface of a chamber of the medical device, the exterior surface of the sealing member having a coating thereon prepared from a curable composition including: (a) a first organopolysiloxane having at least two alkenyl groups; and (b) a second organopolysiloxane having at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane, wherein at least one of the first organopolysiloxane, the second organopolysiloxane or an optional third organopolysiloxane of the curable composition comprises a fluoro group.
US08603635B2	Flexible, molded or extruded articles and semiconductive compounds for their manufacture A molded or extruded article, e.g., an electrical part or shielded cable, comprises at least one insulation layer and at least one semiconductive layer, the semiconductive layer thick and comprising in weight percent: A. 1 to 30 wt % of conductive filler; B. 10 to 90 wt % of a non-olefin elastomer; C. 10 to 90 wt % of an olefin elastomer; and D. Optionally, 0.5 to 2.5 wt % of peroxide. Carbon black and/or metal particulates or powder typically comprise the filler, silicone or urethane rubber the non-olefin elastomer, and EPR or EPDM the olefin elastomer.
US08603634B2	End-capped poly(ester amide) copolymers This invention relates to poly(ester amide)s (PEAs) comprising inactivated terminal amino and carboxyl groups, methods of synthesizing the inactivated PEAs and uses for them in the treatment of vascular diseases.
US08603632B2	Diamond like carbon coating of substrate housings Embodiments of the invention include articles comprising a diamond like carbon coating or doped diamond like carbon coating on one or more surfaces of a plastic substrate or a plastic enclosure. Embodiments of the DLC or doped DLC coatings reduce the gas permeation of the coated plastic or thermoplastic to hydrogen or helium compared to the permeability of the plastic alone. The DLC or doped DLC coatings coating provides a surface resistivity of from about 107 to about 1014 ohm/square and have a transmittance that range from about 0% to about 70% less than the transmittance of the underlying plastic substrate in the range of about 300 nm to about 1100 nm. The DLC coated plastic can be used in environmental enclosures for protecting environmentally sensitive substrates such as semiconductor wafers and reticles.
US08603630B2	Radiation-curable adhesive composition and adhesive sheet A radiation-curable adhesive composition having a base polymer including structural units derived from a monomer A having a functional group a; a monomer B formed from a methacrylate monomer having an alkyl group that includes at least 10 and no more than 17 carbon atoms; and a monomer C that has both a functional group c that reacts with the functional group a and a polymerizable carbon-carbon double bond group, and a main chain of the base polymer is configured from the monomer B and the monomer A, the proportion of the monomer B being at least 50 wt % of the total monomers configuring the main chain; and the base polymer includes a polymerizable carbon-carbon double bond group in a side chain as a result of a portion of the functional group a in the monomer A reacting and bonding with the functional group c in the monomer C.
US08603627B2	Housing and method for making the same A housing is provided which includes an aluminum or aluminum alloy substrate, an aluminum layer and a corrosion resistant layer formed on the aluminum or aluminum alloy substrate in that order. The corrosion resistant layer is an Al—O layer. Then, Gd ions are implanted in the Al—O layer by ion implantation process. The atomic percentages of O in the Al—O gradient layer gradually increase from the side of Al—O gradient layer near the aluminum or aluminum alloy substrate to the other side of Al—O gradient layer, away from aluminum or aluminum alloy substrate. Therefore the housing has a high corrosion resistance. A method for making the housing is also provided.
US08603626B2	Decorative sheet for three-dimensional work A decorative sheet for three-dimensional processing having a support and at least a surface protective layer laminated thereon, where the decorative sheet for three-dimensional processing has a breaking elongation (according to JIS K 7127) exceeding 300% at temperature higher by 40° C. than a thermal deformation temperature of the above support measured by an ASTM D648 method, and the above surface protective layer is obtained by cross-linking and curing an ionizing radiation curable resin composition and has a film thickness of 0.2 to 6.0 μm.
US08603624B2	Prepreg, laminate, metal clad laminate, circuit board, and circuit board for LED mounting Disclosed is a prepreg obtained by impregnating a woven fabric base with a thermosetting resin composition, wherein the thermosetting resin composition contains 80 to 200 volume parts of an inorganic filler per 100 volume parts of a thermosetting resin, and the inorganic filler contains (A) gibbsite aluminum hydroxide particles having an average particle diameter (D50) of 2 to 15 μm, (B) at least one inorganic component selected from the group consisting of boehmite particles having an average particle diameter (D50) of 2 to 15 μm and inorganic particles that have an average particle diameter (D50) of 2 to 15 μm and that contain crystal water having a release initiation temperature of 400° C. or higher or contain no crystal water, and (C) aluminum oxide particles having an average particle diameter (D50) of 1.5 μm or smaller, the compounded ratio (volume ratio) of the gibbsite aluminum hydroxide particles (A), the at least one inorganic component (B) selected from the group consisting of the boehmite particles and the inorganic particles, and the aluminum oxide particles (C) being 1:0.1 to 2.5:0.1 to 1.
US08603621B2	Writing kit with plastic sheets A writing kit including a plastic sheet, a binding and a case with a closing element to hold the plastic sheet in the case. The case has at least one hole at a center portion of the case and the sheet has at least one hole in the sheet. A binding comprising a flexible cord is laced through the hole in the sheet and the case and a clasp slidingly engages the cord.
US08603619B2	Heat-resistant brittle label A laser-markable, acrylic resin-based laminate having a thickness of 100 to 200 μm and including (A3) a pigmented layer made of a crosslinked acrylic resin obtained by crosslinking an acrylic resin composition having a hydroxyl value of 10 to 100 mg KOH/g, (B3) a base layer made of a crosslinked acrylic resin obtained by crosslinking an acrylic resin composition having a hydroxyl value of 18 to 40 mg KOH/g, and (C3) a destructible layer made of a crosslinked acrylic resin obtained by crosslinking a mixture of an acrylic resin composition having a hydroxyl value of 20 to 35 mg KOH/g and polymer beads.
US08603611B2	Transparent planar body and transparent touch switch The present invention provides a transparent planar body and a transparent touch switch that can improve visibility. Specifically, the transparent planar body (1) has a patterned transparent conductive film (12) on at least one surface of a transparent substrate (11). This transparent planar body (1) comprises a transmittance-adjusting layer for equalizing the transmission spectrum of light transmitted through a patterned region wherein the transparent conductive film (12) is provided via the transparent substrate (11) with that transmitted through a non-patterned region wherein the transparent conductive film (12) is not provided via the transparent substrate (11).
US08603606B2	Preventing adhesion between nanostructures A device for Surface Enhanced Raman Scattering (SERS). The device includes a plurality of nanostructures protruding from a surface of a substrate, a SERS active metal disposed on a portion of said plurality of nanostructures, and a low friction film disposed over the plurality of nanostructures and the SERS active metal. The low friction film is to prevent adhesion between the plurality of nanostructures.
US08603602B2	Optional disk and method for manufacturing the same A first substrate is formed to include a surface on which a first record layer is formed, and which includes an inner circumferential portion on which a ring-shaped member is provided. Ultraviolet curing resin is dropped onto part of the surface which is located inward of the ring-shaped member, and the first substrate is then spun to coat the first record layer with the ultraviolet curing resin. Furthermore, a second substrate is formed to include a surface on which a second record layer is formed, and the second substrate is spun to coat the second record layer with ultraviolet curing resin. Then, the first and second record layers are made to face each other, and the first and second substrates are bonded to each other by the ultraviolet curing resin.
US08603601B2	Base for turf system A turf underlayment layer for supporting an artificial turf assembly includes a plurality of panels assembled together, each panel being made from a plurality of polyolefin beads bonded together, each panel further including a core, a top side having a plurality of projections, and a bottom side having a plurality of projections, the top projections forming top side water drainage channels and the bottom projections forming bottom side water drainage channels, the panels having edges, at least one of the panel edges having at least one drainage projection, the drainage projection spacing the abutting panel edges apart, with the resultant spacing of the edges of abutting panels forming a drainage path at the intersection of the abutting panels.
US08603599B2	Resin composition for hollow blow-molded article, hollow blow-molded article, and method of producing the hollow blow-molded article There are provided, according to the present invention, a resin composition for hollow blow-molded article which is obtained in a high productivity on an industrial scale with excellent moldability and drawdown resistance, and the production method thereof, by melting and mixing a polyarylene sulfide resin including a terminal carboxyl group within the resin in an amount of 25 to 45 (μmol/g), and having a non-Newtonian index of 0.90 to 1.15 and also a melt viscosity as measured at 300° C. within the range of 1,000 poise to 3,000 poise and an epoxy group-containing polyolefin so that the proportion of the epoxy group-containing polyolefin is 5 to 30 parts by mass with respect to 100 parts by mass of the polyarylene sulfide resin; and a hollow blow-molded article with excellent mechanical strength, such as the heat resistance and impact resistance, and surface appearance, and the production method thereof.
US08603598B2	Multi-layer insulation composite material having at least one thermally-reflective layer with through openings, storage container using the same, and related methods In an embodiment, a multi-layer insulation (MLI) composite material includes a first thermally-reflective layer and a second thermally-reflective layer spaced from the first thermally-reflective layer. At least one of the first or second thermally-reflective layers includes a plurality of through openings configured to at least partially obstruct transmission therethrough of infrared electromagnetic radiation having a wavelength greater than a threshold wavelength. A region between the first and second thermally-reflective layers impedes heat conduction between the first and second thermally-reflective layers. Other embodiments include a storage container including a container structure that may be at least partially formed from such MLI composite materials, and methods of using such MLI composite materials.
US08603596B2	Liquid crystal display device and electronic device having the same A liquid crystal display device includes an illuminator and a liquid crystal panel for performing displaying by using light which is emitted from the illuminator. The liquid crystal panel includes a pair of substrates and a liquid crystal layer provided therebetween. The liquid crystal layer is formed of a liquid crystal material which contains molecules having at least one of a carbon-carbon triple bond and a polycyclic group. The illuminator includes a light source causing primary generation of at least blue light, among other light which is used for displaying.
US08603592B2	Barrier coatings for polymeric substrates An exemplary embodiment provides coated polymeric substrates that have a polymeric substrate body with a coated surface. The surface coating includes more than one pair of coating layers. Each pair of coating layers includes a first applied coating layer and a second applied coating layer. In addition, an indicator, applied on top of or between coating layers, provides an indication of wear of the coating. The first and second applied coating layers have a thickness between about 3 to about 10 nanometers. The coating exhibits a Hall-Petch effect.
US08603591B2	Enhanced etch and deposition profile control using plasma sheath engineering A plasma processing tool is used to deposit material on a workpiece. For example, a method for conformal deposition of material is disclosed. In this embodiment, the plasma sheath shape is modified to allow material to impact the workpiece at a range of incident angles. By varying this range of incident angles over time, a variety of different features can be deposited onto. In another embodiment, a plasma processing tool is used to etch a workpiece. In this embodiment, the plasma sheath shape is altered to allow ions to impact the workpiece at a range of incident angles. By varying this range of incident angles over time, a variety of differently shaped features can be created.
US08603590B2	Polymer layer comprising silicone and at least one metal trace and a process of manufacturing the same The invention relates to a method of embedding a metal trace in a silicone containing polymer layer, by the steps of applying an agent that does not adhere to a substrate; applying a polymer layer on the non adhering agent; irradiating a surface of the polymer with a light beam emitted by an excimer laser creating cuts, grooves, blind holes or vias; immersing the irradiated polymer in an autocatalytic bath containing metal ions and metallizing the polymer; thermally treating the metallized polymer layer to induce diffusion of the metalized metal into the first polymer layer; applying a polymer layer on the thermally treated metallized polymer; and thermally treating the metallized polymer.
US08603585B2	Method for making carbon nanotube composite A method for making a carbon nanotube composite includes: forming a self-supporting carbon nanotube film structure; providing a hardenable liquid material; immersing the carbon nanotube film structure in the hardenable liquid material; and solidifying the hardenable liquid material to achieve a carbon nanotube composite.
US08603582B2	Non-stick masking fixtures and methods of preparing same Non-stick fixtures for selectively masking portions of a workpiece during application of a workpiece coating are described herein. These fixtures have predetermined surfaces thereon having an average surface roughness of about 25 Ra or less and a Rockwell hardness of about 65 Rc or more. The controlled average surface roughness ensures that these fixtures are non-stick with respect to the workpiece coating being applied to the workpieces disposed therein. The controlled Rockwell hardness ensures that the desired average surface roughness can be maintained throughout repeated use of the fixture in harsh coating environments. These fixtures reduce the workpiece coating bridging that occurs between the fixture and the workpiece, and also reduce the amount of overspray that occurs on the workpiece, thereby minimizing the amount of handwork and/or rework that is necessary after the workpiece is coated. This improves process cycle times and yields significantly.
US08603581B2	Manufacture of n-type chalcogenide compositions and their uses in photovoltaic devices A layer of an n-type chalcogenide compositions including at least cadmium that is provided on a substrate in the presence of an oxidizing gas in an amount sufficient to provide a resistivity to the layer that is less than the resistivity a layer deposited under identical conditions but in the substantial absence of oxygen. Such n-type chalcogenide compositions are particularly useful in the making of photovoltaic devices.
US08603580B2	High stability and high capacity precursor vapor generation for thin film deposition A method for vaporizing a liquid for subsequent thin film deposition on a substrate. The method comprises vaporizing a liquid which is disposed within a tubular porous metal body. The porous metal body comprises a first surface defining a first carrier gas flow path and a second surface defining a second carrier gas flow path in a substantially opposite direct to the first carrier flow path. Vapor is generated from the liquid and added to a carrier gas that passes sequentially in direct contact along the first and second surfaces of the porous metal body to form a gas/vapor mixture with the carrier gas first flowing along the first surface and then along the second surface thereby providing a gas/vapor mixture for thin film deposition.
US08603578B2	Composition and method for making a proppant The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants.
US08603575B1	Thin-film absorber formation method A thin-film absorber formation method includes: operating a furnace having an internal atmosphere containing a process gas; loading process gas material into a source container that is part of a system configured to provide process gas to the furnace, wherein loading of the source container occurs without exposing the internal atmosphere of the furnace to external atmosphere present in the source container by solidifying process gas material to form a gas tight seal to separate the source container from the furnace, wherein the seal is formed before the source container is opened for loading and external atmosphere enters the source container, including a pathway configured to retain process gas material in a section of the pathway to solidify and create the seal.
US08603571B2	Consumable tool friction stir processing of metal surfaces The surface composition of a metal article may be modified by depositing a coating layer material of a different composition from a consumable tool which is urged against the article surface while being rotated about an axis generally normal to the surface. The frictional heating resulting from rotation of the tool under applied pressure increases the temperature of the article-contacting portion of the tool so that it adheres to and bonds to the magnesium alloy article. In an embodiment the tool material is selected to be more corrosion-resisting than or sacrificial to the substrate metal alloy. In another embodiment the tool material is selected to react with the magnesium surface to form a more corrosion-resistant coating or a sacrificial layer. In another embodiment a holemaking cutting tool may be incorporated in to the consumable tool to enable fabrication of a hole with a surrounding, more corrosion-resistant annular surface. Further processing of the article with its coating layer may include: buffing, burnishing, or polishing the layer; and heat treatment to promote diffusion of the layer composition into the article composition.
US08603570B2	Fiber modified layer and methods of making and using same A method of selecting a fiber modified layer for applying on an existing surface, comprising the steps of: providing a binder mixture having an effective amount of an aggregate material, a binder, and a plurality of fibers, wherein each of the plurality of fibers has a length greater than 0.25 inches; applying the binder mixture to a selected surface to form a fiber modified proposed layer; testing the fiber modified proposed layer for fatigue or crack resistant properties, where testing the fiber modified proposed layer for fatigue or crack resistant properties comprises using a Modified Disc Compact Tension Test in accordance with Modified ASTM D7313-07; and selecting the binder mixture for application on the existing surface for performance if the fiber modified proposed layer has fatigue or crack resistant properties.
US08603568B2	Hydrolyzed lecithin product to improve digestibility A specific lecithin composition comprising phospholipids and lysophospholipids is described that can be used as an animal feed additive for the improvement of digestibility parameters and consequently gut health and animal performance. In addition, the mixture possesses useful biological and chemical properties that can be utilized in the animal feed and human food industries. The composition is chemically characterized by means of HPLC-ELSD, HPLC-MS/MS and 31P-NMR and its biological functionalities are fully described.
US08603563B2	Methods for coffee cherry products Methods are provided for isolating a nutrient from coffee cherries or for producing a food product that comprises a coffee cherry or portion thereof. It is particularly preferred that coffee cherries will have an extremely low concentration of mycotoxins, including various aflatoxins, fumonisins, ochratoxins, and/or vomitoxin (DON, deoxynivalenol).
US08603562B2	Coffee-derived surfactants Coffee-derived surfactants are provided by transesterification reactions of sugars and coffee oil. The coffee-derived surfactants are especially useful in the production of coffee oil emulsions for use with, or incorporation into, coffee products.
US08603561B2	Coffee extract having red fruits and coffee aroma The present invention relates to the development and obtention of a liquid coffee extract bearing a combined natural coffee and red fruits aroma which modifies the aroma but keeps unaltered the coffee taste.
US08603560B2	Milk protein isolate and process for its preparation The invention relates to a novel process for isolating milk proteins from milk or from whey; its subject is also a milk protein fraction obtained by this process and its use for the preparation of pharmaceutical or food compositions.
US08603557B2	Containers and methods for dispensing multiple doses of a concentrated liquid, and shelf stable concentrated liquids Containers and methods are provided for dispensing a liquid concentrate utilizing one or more desirable properties including a generally consistent discharge across a range of squeeze forces, a generally consistent discharge with the same force without significant dependence on the amount of liquid concentrate in the container, a substantially dripless or leak proof outlet opening, a jet that minimizes splashing when the liquid concentrate impacts a target liquid, and a jet that maximizes mixing between the liquid concentrate and the target liquid to produce a generally homogenous mixture without the use of extraneous utensils or shaking. Also provided are liquid beverage concentrates that can be cold filled during packaging while maintaining shelf stability for at least about three months at ambient temperatures. Concentrates are provided having low pH, with or without alcohol, and with buffers to allow for increased acid content at a selected pH.
US08603556B2	Fried-chunk food compositions The invention provides fried-chunk food compositions comprising (1) food chunks that have been fried in oil at a temperature of from about 110 to 205° C. to produce fried food chunks having a moisture content of about 16% and an Aw of about 0.7 and (2) from about 5 to about 35% plasticizer applied to the fried food chunks, wherein the fried food chunks with applied plasticizer have a moisture content of about 12% or less and an Aw of about 0.65 or less. The compositions are made without using preservatives, have a desirable texture and appealing meat-like appearance, and are shelf-stable and therefore do not spoil due to unwanted microbial growth.
US08603550B1	Compositions for topical treatment A stable, self-preserving, antimicrobial, composition suitable for the treatment of a variety of dermal as well as subcutaneous conditions. The compositions include as an active ingredient a quaternary ammonium compound, preferably benzethonium chloride, potentiated and synergized with menthyl lactate cooling agent in a cationic carrier. Optionally, a phenoxyethanol preservative and chlorhexidine digluconate antibacterial agent may be used to assist in enhancing the activity. The compositions kill a broad spectrum of gram-negative and gram-positive bacteria, fungus and yeasts. The compositions are used as first aid skin treatments and as skin sanitizers to help prevent bacterial contamination of minor cuts, scrapes and burns. The compositions are particularly useful when applied to the skin after hair removal in that they additionally cool, soothe and moisturize the skin. The compositions may also serve as a base vehicle in which additional skin care ingredients may be added to provide additional functionality to the compositions.
US08603549B1	Systems and methods for inhibiting formation of stretch marks According to the invention, a method for inhibiting the formation of stretch marks is disclosed. The method may include applying an oil to a portion of a person's body. The method may also include placing a non-absorbent film over the oil on the portion of the person's body. The method may further include securing the non-absorbent film to the person's body.
US08603545B2	Cosmetic and pharmaceutical uses of an extract of a plant belonging to the genus Buchholzia A cosmetic or dermopharmaceutical composition including an extract of a plant belonging to the genus Buchholzia and at least one auxiliary and/or additive is provided. A method for the cosmetic treatment of the skin or scalp and a method for the treatment of skin inflammation includes administering to a patient in need thereof a composition including an effective amount of a plant extract from a plant belonging to the genus Buchholzia.
US08603544B2	Calcium carbonate granulation Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
US08603540B2	Avian-based insect repellent The invention provides an insect repellent that repels flies, gnats, mosquitoes, lice, ticks, and fleas. The insect repellent comprises an avian-based extract, in particular an extract isolated from birds of the order Psittaciformes (parrots). The invention also provides an insect repellent composition about 5 volume % to about 75 volume % of the avian-based extract and about 95 volume % to about 25 volume % of a carrier vehicle.
US08603539B2	Compositions for drug delivery Substantially non-porous polymeric microparticles comprising a hydrophobic polymer and a plasticizer, and containing therein a bioactive or bioinactive agent.
US08603538B2	Process for the production of an n-butyric acid compound in micro encapsulated form, for animal or human consumption A process for the production of an n-butyric acid compound in microencapsulated form comprises the stages of:—providing a granular material based on the n-butyric acid compound, —mixing the granular material with a matrix having a content of long-chain C14-C22 saturated fatty acids of from 40% to 95%, and an amount of between 1% and 20% of a mineral agent in which an effective amount of calcium sulphate dihydrate is present, heating the mixture to a temperature higher than the melting temperature of the lipid component of the matrix, —spraying the mixture into a cooling chamber having a temperature lower than the melting temperature of the lipid component of the matrix, so that the latter solidifies around the granular material, forming a covering thereof.
US08603534B2	Drug loaded polymeric nanoparticles and methods of making and using same The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic)acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.
US08603533B2	Polymersomes and production method thereof It is an object of the invention to provide a polymersome excellent in the safety and feeling in use; in particular, there is no sticky feeling but there is a good refreshing feeling; and with excellent base-agent stability. A polymersome of the present invention comprises a block-type alkylene oxide derivative represented by the following formula (I) as the membrane component: R1O-[(EO)l(AO)m(EO)n]—R2 (I) wherein AO is an oxyalkylene group having 3 to 4 carbon atoms, EO is an oxyethylene group, m and 1+n are the average addition mole numbers for the oxyalkylene group and the oxyethylene group, respectively, and 1≦m≦70, 1≦l+n≦70; the percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 20 to 80 mass %; the addition pattern of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is block-type; and R1 and R2 are identical or different hydrocarbon groups having 1 to 4 carbon atoms.
US08603532B2	Nanostructures for drug delivery The present invention provides compositions, preparations, formulations, kits, and methods useful for treating subjects having cancer or at risk of developing cancer. Some embodiments of the invention may comprise a composition comprising a plurality of particles comprising a platinum(IV) therapeutically active precursor.
US08603520B2	Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors An oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a first population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a first rate; a population of a basic substance; and a second population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a second rate. In another embodiment, the oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a population of a pharmaceutical active; a population of a basic substance; a population of enteric coated pharmaceutical active; and a population of enteric coated basic substance. The composition can provide multiple site specific delivery of a pharmaceutical active in a rapid, delayed and/or sustained release manner into the plasma.
US08603516B2	Buccal drug delivery A lozenge is provided that has stable pH and stable levels of active ingredient over time. It comprises a combination of (i) at least one gum and (ii) at least one non-crystallising sugar or non-crystallising sugar alcohol in a matrix designed for controlled buccal delivery of a drug. The lozenge also contains water and optional components selected from flavorings, taste masking agents, colorings, buffer components, pH adjusting agents, excipients, stabilizers and sweeteners. Methods of preparing the lozenge are also provided.
US08603515B2	Pharmaceutical formulation The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.
US08603510B2	Semiochemical reservoir to attract subterranean termites tunneling in soil The present invention relates generally to polymer devices impregnated with semichemical attractants for termites. The materials for delivering the semiochemicals are preferably cellulose-free. Devices of the subject invention are placed in soil and provide a slow-release and permeation of the semiochemicals into the adjacent soil so that termites tunneling in the vicinity are directed toward the chemical sources. Because the semiochemicals are impregnated in the polymer, the device also protects the semiochemicals so that they do not degrade rapidly under field conditions. In a preferred embodiment, the subject invention comprises a durable station housing, preferably with a removable bait, wherein the body of the station housing itself is impregnated with a semiochemical attractant.
US08603507B2	Silicone oil emulsion, method of producing same, and silicone oil composition To provide a silicone oil emulsion that can improve the properties of cosmetic materials and that contains crosslinked silicone particles in water-dispersed silicone oil droplets; a method of producing this silicone oil emulsion; and a silicone oil composition thereof. This invention is a silicone oil emulsion comprising crosslinked silicone particles having an average particle size of 0.05 to 100 μm in silicone oil droplets that are dispersed in water and that have an average particle size of 0.1 to 500 μm wherein the silicone oil is an alkyl-modified silicone oil that has a silicon-bonded alkyl group having at least 4 carbons and the crosslinked silicone particles preferably have a silicon-bonded alkyl group having at least 4 carbons. Also, a silicone oil composition as provided by removing the water from this silicone oil emulsion.
US08603506B2	Methods of treating acne A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
US08603499B2	Cancer cell targeting using nanoparticles The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries.
US08603481B2	Therapeutic agents for solid tumors A therapeutic agent for solid tumors, the agent comprising as an active ingredient, an antibody that specifically binds to a protein having the amino acid sequence represented by SEQ ID NO:2 or an antibody fragment maintaining the antibody activity.
US08603479B1	Class I anti-CEA antibodies and uses thereof The present invention provides compositions and methods of use of humanized, chimeric or human Class I anti-CEA antibodies or fragments thereof, preferably comprising the light chain variable region CDR sequences SASSRVSYIH (SEQ ID NO:1); GTSTLAS (SEQ ID NO:2); and QQWSYNPPT (SEQ ID NO:3); and the heavy chain variable region CDR sequences DYYMS (SEQ ID NO:4); FIANKANGHTTDYSPSVKG (SEQ ID NO:5); and DMGIRWNFDV (SEQ ID NO:6). The Class I anti-CEA antibodies or fragments are useful for treating diseases, such as cancer, wherein the diseased cells express CEACAM5 and/or CEACAM6 antigens. The Class I anti-CEA antibodies or fragments are also of use for interfering with specific processes, such as metastasis, invasiveness and/or adhesion of cancer cells, or for enhancing sensitivity of cancer cells to cytotoxic agents and have favorable effects on the survival of subjects with cancer.
US08603477B2	Use of anti-CS1 antibodies for treatment of rare lymphomas Uses of anti-CS1 antibodies, alone or in combination with other agents, for the treatment of rare lymphomas, such as NK lymphomas, NK/T-cell lymphomas, and angioimmunoblastic lymphomas.
US08603475B2	Methods and compositions for targeting polyubiquitin Anti-polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
US08603472B2	Methods and compositions reversing pre-diabetes using fusion proteins comprising a GAD peptide The present invention relates generally to methods and compositions for treatment of, including reversing, pre-diabetes. More specifically, the present invention relates to the administration of a fusion protein comprising at least one immunoglobulin having one or more diabetogenic epitopes including, inter alia, GAD2, inserted within a variable region thereof, for treating or reversing pre-diabetes in a subject.
US08603471B2	Methods and compositions for preventing the onset of type 1 diabetes The present invention relates generally to methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes. More specifically, the present invention relates to the administration of a fusion protein comprising at least one immunoglobulin having one or more diabetogenic epitopes inserted within the variable region, for suspending, preventing or delaying the onset of type 1 diabetes in a pre-diabetic subject.
US08603469B2	Methods of treating cancer with human monoclonal antibodies against interleukin 8 Isolated human monoclonal antibodies which bind to IL-8 (e.g., human IL-8) are disclosed. The human antibodies can be produced in a hybridoma, transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, hybridomas, and transfectomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
US08603468B2	Neutralization of HCV Aspects of the present invention concern compositions that induce and/or improve an immune response to hepatitis C virus (HCV). Methods of making and using compositions that include epitopes of the HCV E2 structural protein involved in promoting or inhibiting neutralization of HCV are provided.
US08603464B2	Alkaline phosphatase to reduce weight gain or induce weight loss The present invention provides methods for using human placental alkaline phosphatase or an active derivative to reduce blood glucose level in a mammal. Treatment regimens provided by the invention may be used to control Type 1 and Type 2 forms of diabetes in humans. The methods and treatment regimens may be effective to maintain the human's blood glucose level below about 10 mM, and preferably within the normal range of 4 mM to 7 mM. The methods and treatment regimens may be used in combination with administration of known anti-diabetic medicaments. Also provided by the invention is a method for inducing weight loss or reducing an expected weight gain caused by or associated with obesity or Type 2 diabetes. The invention further provides a preparation for administration to a human, the preparation comprising homogeneous purified human placental alkaline phosphatase in a physiologically acceptable carrier.
US08603463B2	Recovery of tissue function following administration of B cells to injured tissue The present invention relates generally to systems and methods of enhancing recovery of function of injured tissue through administration of a composition comprising a relatively pure populations of B lymphocyte cells in a pharmaceutically acceptable carrier to the injured tissue. Kits are provided to aid in purification of B cells from heterogeneous mixtures of cells and administration of B cells to injured tissue.
US08603460B2	Method of making a Lactobacillus reuteri with increased acid tolerance The invention provides certain plasmid cured strains of lactic acid bacteria modified for their capability of better acid-tolerance, a method of modifying such strains, and products containing such strains.
US08603458B2	Genetic adjuvants for immunotherapy The present invention pertains to methods and pharmaceutical compositions for modulating an immune response. The method of the present invention involves administration of an effective amount of nucleic acid molecules encoding interleukin-12 (IL-12), interferon-gamma (IFN-γ), or a combination thereof, to a patient in need of such treatment. The pharmaceutical compositions of the invention contain nucleic acid molecules encoding IL-12 and/or IFN-γ and an operably-linked promoter sequence. In another aspect, the present invention concerns expression vectors containing a nucleotide sequence encoding IL-12 and IFN-γ, and an operably-linked promoter sequence. In another aspect, the present invention concerns cells genetically modified with a nucleotide sequence encoding IL-12 and IFN-γ.
US08603453B2	Antimicrobial polymeric biguanide and acidic co-polymer composition and method of use A composition comprising: (i) an anti-microbial agent; and (ii) an acidic co-polymer of the Formula (1) wherein: [A] is of Formula (9), [B] is of Formula (10), and [C] is of Formula (12), wherein: [X] is of Formula (11), wherein [A], [B] and [C] may occur in any order; T is an optionally substituted substituent; L and G each independently is an optionally substituted linking group; R1, R2 and R3 are each independently H, optionally substituted C1-20-alkyl or optionally substituted C3-20-cycloalkyl; R4 and R5 are each independently H or C1-4-alkyl; q is 15 to 1000; p is 3 to 50; J is an optionally substituted hydrocarbyl, group; F is an acidic substituent; b is 0, 1, or 2; m is 0 to 350; n is 1 to 75; v is 1 to 100; and w is 1 to 4; provided that at least one of R4 and R5 is H and provided that R1, R2, R3, T, L, J and G do not contain a basic group; and wherein the pka value of the acidic substituent F on the monomer from which [C] is derived is less than 5.5.
US08603450B2	Shower and shave preparation A cosmetic cleansing and shaving preparation which comprises a surfactant system of (i) one or more amphoteric surfactants and (ii) one or more anionic surfactants, the weight ratio (i):(ii) being greater than about 1:1. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.
US08603449B2	Rinse-off conditioning composition comprising a near-terminal branched alcohol A rinse-off conditioning composition comprising: (a) near-terminal branched alcohol according to Formula I; (b) a cationic surfactant; (c) a terminal aminosilicone; wherein the near-terminal branched alcohol and the cationic surfactant are comprised in a lamellar gel matrix.
US08603442B2	Tooth sensitivity treatment compositions A tooth sensitivity treatment composition is disclosed. The composition includes a compound of formula I M1-A-M2-B-M1 (I) wherein: M1 is a monovalent or divalent metal; M2 is a polyvalent metal or metal oxide; and A and B are, independently, selected from the group consisting of C2-C6 diacids, triacids, and tetraacids. Methods for treating tooth sensitivity are also disclosed.
US08603441B2	Functionalized calcium phosphate hybrid systems for confectionery and foodstuff applications A method of whitening teeth, including an application of functionalized calcium phosphate additives generated via a solid-state method. The additives were produced by placing predetermined amounts of inorganic and inorganic materials and milling media into a vessel rotatably connected to a turntable platform, an amount of an organic material into the vessel, rotating the vessel in a first direction while turning the turntable platform in a second direction counter to the first direction, with the resultant material defining the functionalized calcium phosphate. The inorganic material may include calcium phosphates of varying phases, structure, and composition. The organic material may include anionic surfactants, cationic surfactants, neutral surfactants, carboxylic acids, polymers, copolymers, block copolymers, and combinations thereof. Once produced, the additives were added to comestibles, such as in confectionery and foodstuff formats, for delivery to the teeth and dental structures.
US08603436B2	Methods and compositions for targeted drug delivery Disclosed are Drug Delivery Molecules (DDMs) which both facilitate functional imaging, as by PET, MRI or SPECT, and create a biological effect and methods of their use. These DDMs which are variously designed to target specific receptors, internalized and then function biologically, as for purposes of cell destruction or therapy.
US08603432B2	Transition metal/zeolite SCR catalysts A method of converting nitrogen oxides in a gas to nitrogen by contacting the nitrogen oxides with a nitrogenous reducing agent in the presence of a zeolite catalyst containing at least one transition metal, wherein the zeolite is a small pore zeolite containing a maximum ring size of eight tetrahedral atoms, wherein the at least one transition metal is selected from the group consisting of Cr, Mn, Fe, Co, Ce, Ni, Cu, Zn, Ga, Mo, Ru, Rh, Pd, Ag, In, Sn, Re, Ir and Pt.
US08603429B2	Production system and production method for carbon fiber thread Disclosed is a production system (1) for a carbon fiber thread (Z) by continuously subjecting a carbon fiber thread precursor (X) having a jointed portion (a) connecting respective ends of two carbon fiber thread precursors (X) to heat treatment, which contains an oxidization oven (10) for subjecting the carbon fiber thread precursor (X) to an oxidization treatment, a carbonization furnace (12) for subjecting a thus obtained oxidized fiber thread to a carbonization treatment, a winder (18) for winding the carbon fiber thread (Z) around a winding bobbin, a detection means (24) for detecting the jointed portion (a), a positional information-acquisition means (26) for acquiring positional information of the jointed portion (a), a control means (28) for controlling the winder (18) in such a way that a carbon fiber thread including the jointed portion (a) and a carbon fiber thread not including the jointed portion (a) are separately wound up around different winding bobbins based on the positional information. Also disclosed is a production method for a carbon fiber thread by use of the production system (1).
US08603428B2	Method of producing calcium carbonate from waste and by-products The present invention concerns a method for producing calcium carbonate containing the steps of extraction of alkaline industrial waste or by-products using as a first extraction solvent an aqueous solution of a salt formed from a weak acid and a weak base, whereby a vanadium-enriched first residue is allowed to settle and a calcium-rich first filtrate is formed, filtration, whereby the first filtrate is separated from the first residue, carbonation of the calcium-rich first filtrate using a carbonation gas, whereby calcium carbonate precipitates and a second filtrate is formed, and a second filtration, whereby the calcium carbonate is separated from the second filtrate. Further, the present invention concerns a method for extracting calcium carbonate and vanadium from alkaline industrial waste or by-products.
US08603427B2	Ammonia recovery device and recovery method A method includes a first step of, with a CO2.H2S stripper maintained to have a pressure higher than atmospheric pressure, from the ammonia-containing wastewater, discharging CO2 and H2S in a form of gas having a low moisture concentration from a tower top of the CO2.H2S stripper while discharging an ammonia-containing solution from a tower bottom of the CO2.H2S stripper; a second step of introducing the ammonia-containing solution obtained after the first step into an ammonia stripper which is maintained to have a lower pressure than that of the CO2.H2S stripper, and thereby discharging a gas rich in ammonia containing a small amount of H2S and CO2 from a tower top of the ammonia stripper while discharging water usable as industrial water from a tower bottom of the ammonia stripper; and a third step of introducing the ammonia rich gas obtained after the second step into a washing tower which is maintained to have a lower pressure than that of the ammonia stripper, and thereby discharging a wastewater containing a Na compound from a tower bottom of the washing tower while discharging a H2S-free gas rich in ammonia from a tower top of the washing tower.
US08603426B1	Method of making a silicon-containing film A method of making hydrogenated Group IVA compounds having reduced metal-based impurities, compositions and inks including such Group IVA compounds, and methods for forming a semiconductor thin film. Thin semiconducting films prepared according to the present invention generally exhibit improved conductivity, film morphology and/or carrier mobility relative to an otherwise identical structure made by an identical process, but without the washing step. In addition, the properties of the present thin film are generally more predictable than those of films produced from similarly prepared (cyclo)silanes that have not been washed according to the present invention. The present invention advantageously provides semiconducting thin film structures having qualities suitable for use in electronics applications, such as display devices or RF ID tags, while enabling high-throughput manufacturing processes that form such thin films in seconds or minutes, rather than hours or days as with conventional photolithographic processes.
US08603424B2	CO2-sequestering formed building materials CO2-sequestering formed building materials are provided. The building materials of the invention include a composition comprising a carbonate/bicarbonate component. Additional aspects of the invention include methods of making and using the CO2-sequestering formed building material.
US08603423B2	Three way catalyst comprising extruded solid body A three way catalyst includes an extruded solid body having: 10-95% by weight of at least one binder/matrix component; 5-90% by weight of a zeolitic molecular sieve; and 0-80% by weight optionally stabilized ceria. The catalyst further includes at least one precious metal and optionally at least one non-precious metal. The at least one precious metal is carried in a coating layer on a surface of the extruded solid body; at least one metal is present throughout the extruded solid body and at least one precious metal is also carried in a coating layer on a surface of the extruded solid body; or at least one metal is present throughout the extruded solid body, is present in a higher concentration at a surface of the extruded solid body and at least one precious metal is also carried in a coating layer on the surface of the extruded solid body.
US08603420B2	Galvanic waste sludge treatment and manufacturing of nano-sized iron oxides The invention enables processing waste sludge after galvanic treatment of metals, and particularly recycling spent pickling acids after pickling. Provided is an environmentally friendly process, which yields acids for reuse, and pure nano-sized iron pigments as a side product.
US08603419B2	Method of treating an alkaline granular carbonatable material The invention concerns a method of treating an alkaline granular carbonatable material which contains aluminium metal and which has in particular a pH of at least 10. The method comprises an oxidation step wherein at least a portion of said aluminium metal is oxidized by contact with moisture. The aluminium should be oxidized to avoid swelling problems when using the granular material as aggregate. In the method according to the invention this oxidation is accelerated by providing at least one oxidizing agent in said moisture, which oxidizing agent has a higher redox potential than the water contained in said moisture. The method further comprises a carbonation step wherein the granular carbonatable material is at least partially carbonated to lower the pH thereof. In this way the formation of ettringite, which may also release aluminium ions which causing further swelling problems, can be avoided in the granular material or any ettringite present therein can be destabilized.
US08603414B2	Micro-chemical analysis device, microchemical measuring method, and sample collecting tool A micro-cassette 1 stores a sample, a reagent, and an additive, and comprises a sensor measures the component of measurement item. Analysis device 2 comprises liquid control unit controls each liquid in micro-cassette 1. Mixing controller 33 mixes the sample and the additive sent to sample processing unit 13, and generates the first sample includes a formed element. Isolation unit 14 generates the second sample from the first sample sent from sample processing unit 13. Sensor 18 measures the compound liquid of the second sample and reagent, and generates the analysis signal.
US08603413B2	Electrode addressing method A device for addressing an electrode array of 2n lines of an electro-fluidic device, each line having N electrodes (n≦N). The device includes, on each line, n selection electrodes, all of the line selection electrodes being connected to 2n line selection conductors, 2n−1 line selection electrodes of 2n−1 lines being connected to each line selection conductor, and selection devices for selecting one or more line selection conductors.
US08603407B2	Catalytic isobutane alkylation A novel catalytic reactor is provided for controlling the contact of a limiting reactant with a catalyst surface. A first flow vessel defines an interior surface and an exterior surface, and the interior surface has a catalyst deposited on at least a portion thereof. A second flow vessel is positioned within the first flow vessel and the second flow vessel defines a porous surface designed to deliver a fluid uniformly to at least a portion of the interior surface of the first flow vessel.
US08603405B2	Power units based on dislocation site techniques A distributed energy system includes a gas-loaded heat generator capable of producing a thermal energy. The system includes a gas source to provide one or more isotopes of hydrogen, a plurality of metallic micro-structures, a gas loading chamber containing the plurality of metallic micro-structures. The gas loading chamber is structured to receive the one or more isotopes of hydrogen from the gas source. The system also includes a gas loading system capable of providing a gas loading pressure to the gas loading chamber containing the plurality of metallic micro-structures with an amount of one or more isotopes of hydrogen to form hydrogen clusters. In one form, the system further includes a thermal transducer capable of converting a first portion of the thermal energy. In still another form, the system additionally includes a waste heat recovery device capable of applying a second portion of the thermal energy.
US08603404B2	Apparatus and process for thermal decomposition of any kind of organic material A Low Temperature Conversion apparatus composed of tri-tubes which simultaneously carries out the functions of vessel and heat exchanger is provided. The apparatus is capable of thermally decomposing any kind of organic material to obtain coal, oil, water and non-condensable gases, and also decontaminating soils and residues contaminated with organochlorides and dioxins and comprises: an outer box (2) with a hermetic lid (19); a thermal insulation layer (5) disposed throughout the inner surface of the outer box (2) and lid; and at least a structure with three concentric tubes disposed internally, positioned substantially vertically and with a wall width suitable for heating by means of gases from an inner side and outer side of said structure. An associated process for thermal decomposition using the apparatus is also provided.
US08603395B2	Self-propelled sensor apparatus for in situ analysis of enviromental parameters A self-propelled apparatus for analyzing a component contained in a fluid medium. The self-propelled apparatus uses kinetic energy of the apparatus to drive a fluid under analysis through the apparatus. This is accomplished by use of a conveyance system that is attached to the analytical system of the apparatus. A sensor system is used to analyze the component collected within the confines of an analysis chamber, a part of the analysis system. The invention also includes a method of using the analytical apparatus.
US08603394B2	Measurement system with distributed functions An analysis system is provided which comprises an integrated analysis device and a test strip magazine, for determining an analyte in a body fluid, wherein the analysis system comprises a first group comprising reusable components and a second group of components comprising a plurality of disposable articles. The second group includes non-electronic and electronic components, with critical interfaces configured between two or more such components, wherein non-electronic components can be disconnected from electronic components at a disconnection point. In one embodiment, critical interfaces are produced and tested during production of the analysis system.
US08603392B2	Electrolyzed water system Corrosion-inhibited hypochlorite compositions and methods of use are disclosed. Corrosion inhibitors including sugar acids and calcium compounds, polyacrylate and calcium compounds, and/or zinc and calcium compounds are used with hypochlorite sources to enhance the longevity and performance of electrochemical cells as well as reducing corrosion of metal in contact with the generated hypochlorite sources. The methods for generation employ a variety of electrochemical cells, beneficially including use of portable electrochemical cell system for production of corrosion-inhibited hypochlorite cleaning solutions.
US08603388B2	Method for obtaining a biocompatible composite implant The invention concerns a method for obtaining a metal implant for open porosity tissue support and/or replacement, characterized in that it comprises the following steps: (i) selecting a mould, (ii) arranging in the mould a solid metal core (7), (iii) filling the volume of the mould (1) still available with a powder of microspheres (3), (iv) consolidating the microspheres (3) with each other as well as with said at least one solid core (7) by electrical discharge sintering.
US08603383B2	Original and article manufacturing method using same The original of the present invention has a pattern to be transferred. For example, the original of the present invention is a mold for use in an imprint apparatus or a mask for use in an exposure apparatus. The original has a negative effective Poisson's ratio. Alternatively, the original has an effective Poisson's ratio smaller than that of a quartz glass plate.
US08603382B2	Plastics molding system and optical element formed by the same A molding method of a plastic molded product includes preparing at least one mold including a high-precision surface; preparing a plurality of molds having a low-precision surface; sequentially supplying molten resin to one of the plurality of molds having low-precision surface; sequentially cooling, for a predetermined length of time, the molds supplied with the molten resin while applying pressure, taking out a molded member from the cooled mold, setting the molded member which has been taken out in the mold having the high-precision surface, and melting only a surface of the molded member while pressing the high-precision surface against the surface to form a plastic molded product.
US08603376B1	Railroad direct fixation tie covering system A method and an apparatus for the protection of a railroad rail, a direct fixation plate or another support unit, a rail to rail connection and a rail to plate connection contacting with concrete upon placing of concrete during construction. The method comprises a step of disposing a mask over a railroad track having a railroad rail, a rail connector and a rail tie to protect the railroad track while placing concrete, the mask configured to cover the rail connector and tie. The mask has a connecting portion, a central portion, an extending portion configured to mask an upper longitudinally extending portion of a railroad rail, and at least one perpendicular section disposed to cover a railroad tie, direct fixation plate or other support unit.
US08603375B2	Method of constructing a storage tank for cryogenic liquids A new procedure for constructing cryogenic storage tanks involves erecting a freestanding metal liner. The liner is sized and configured to withstand the hydraulic forces the concrete wall of the tank being poured without the need for temporary stiffeners on the inside surface of lower portions of the liner. Lateral tension ties can be connected to anchor ties on an outward surface of the liner and used to tie the liner to outer formwork. These ties may be spaced up to about 2 m apart. Studs can also be provided on the outer surface of the liner, and a cylindrical ring of cryogenic steel can be integrated into the liner.
US08603373B2	Method for producing particles, method for producing toner, and apparatus for producing particles A method for producing particles, including: bringing a compressive fluid into contact with a pressure plastic material, so as to produce a melt of the pressure plastic material; and discharging the melt of the pressure plastic material by differential pressure to a space, so as to form particles, wherein the discharging includes at least one of (A) discharging the melt of the pressure plastic material while a compressive fluid is supplied to the melt of the pressure plastic material, and (B) discharging the melt of the pressure plastic material through one or more through-holes, to which vibration is applied, so as to change the shape of the melt of the pressure plastic material from a columnar shape, through the columnar shape with constrictions, into a particle shape.
US08603372B2	Method of manufacturing optical element, and optical element A method of manufacturing an optical element having a good reflection preventing characteristic is provided in which an irregularity structure having a reflection preventing function can be formed at low temperature. The method includes forming a film on the optical substrate by using a coating liquid containing a metal alkoxide containing at least aluminum, immersing the film in a water-containing liquid, baking the film having been immersed in the water-containing liquid, and subjecting the film having been baked to treatment with warm water to form an aluminum-containing film having a fine irregularity structure.
US08603367B2	Manganese phosphates and related electrode active materials The invention provides electrode active materials comprising lithium or other alkali metals, manganese, a +3 oxidation state metal ion, and optionally other metals, and a phosphate moiety. Such electrode active materials include those of the formula: AaMnbMIcMIIdMIIIePO4 wherein (a) A is selected from the group consisting of Li, Na, K, and mixtures thereof, and 0
US08603363B1	Compositions for extending ion source life and improving ion source performance during carbon implantation A novel method and system for extending ion source life and improving ion source performance during carbon implantation are provided. Particularly, the carbon ion implant process involves utilizing a dopant gas mixture comprising carbon monoxide and one or more fluorine-containing gas with carbon represented by the formula CxFy wherein x≧1 and y≧1. At least one fluorine containing gases with carbon is contained in the mixture at about 3-12 volume percent (vol %) based on the volume of the dopant gas mixture. Fluoride ions, radicals or combinations thereof are released from the ionized dopant gas mixture and reacts with deposits derived substantially from carbon along at least one of the surfaces of the repeller electrodes, extraction electrodes and the chamber to reduce the overall amount of deposits. In this manner, a single dopant gas mixture provides carbon ions and removes problematic deposits typically encountered during carbon implantation.
US08603361B2	Fluorescent substance and light-emitting device employing the same Provided is a fluorescent substance excellent in quantum efficiency and in temperature characteristics, and a light-emitting device utilizing the fluorescent substance. This fluorescent substance contains an inorganic compound comprising a metal element M, a trivalent element M1 other than the metal element M, a tetravalent element M2 other than the metal element M, and either or both of O and N. In the inorganic compound, the metal element M is partly replaced with a luminescence center element R. The crystal structure of the fluorescent substance is basically the same as Sr3Al3Si13O2N21, but the chemical bond lengths of M1-N and M2-N are within the range of ±15% based on those of Al—N and Si—N calculated from the lattice constants and atomic coordinates of Sr3Al3Si13O2N21, respectively. The fluorescent substance emits luminescence having a peak in the range of 490 to 580 nm when excited with light of 250 to 500 nm.
US08603357B2	Polymerizable chiral compound, polymerizable liquid crystal composition, liquid crystal polymer and optically anisotropic body The present inventions to provide a novel polymerizable chiral compound (chiral agent) having high helical twisting power, a polymerizable liquid crystal composition comprising the polymerizable chiral compound and a polymerizable liquid crystal compound, a liquid crystal polymer, and an optically anisotropic body. The object was achieved by a polymerizable chiral compound represented by the following formula (I), a polymerizable liquid crystal composition comprising the polymerizable chiral compound and a polymerizable liquid crystal compound, a liquid crystal polymer, and an optically anisotropic body: wherein Y1 to Y8 are each —O—, —O—C(═O)—, —C(═O)—O— or the like; G1 and G2 are each a divalent aliphatic group having 1 to 20 carbon atoms or the like; Z1 and Z2 are each an alkenyl group having 2 to 10 carbon atoms or the like; Q1 to Q4 are each a hydrogen atom or the like; A1 to A6 are each a divalent aromatic group A having 6 to 30 carbon atoms; and X is any of groups represented by the following (X-i) to (X-vi): wherein * represents a bond and L1 to L4 are each an alkyl group having 1 to 4 carbon atoms or the like; and wherein, in the formula (I), a and b are each 0 or 1.
US08603352B1	Chrome-free methods of etching organic polymers A chrome-free composition of an acidic suspension of manganese compounds and manganese ions are applied to an organic polymer surface to etch the surface. The etched surface is then plated with metal.
US08603350B2	Method of manufacturing substrate for information storage media A manufacturing method is provided for manufacturing a substrate for information storage media having various properties that are demanded for a next generation of information storage media substrate purposes exemplified by perpendicular magnetic recording systems, etc., and above all, having high fracture toughness and a smooth surface at low cost. The method of manufacturing a substrate for information storage media includes a step of preparing glass material of a plate shape containing SiO2 component, Al2O3 component, and R′2O component, R′ being at least one selected from Li, Na, and K, and the step of lapping includes at least one sub-step of lapping the glass material with a diamond pad.
US08603348B2	Method of reducing main pole corrosion during aluminum oxide etch A method of removing an alumina layer around a main pole layer during perpendicular magnetic recording head fabrication is disclosed. The alumina etch sequence includes immersing a substrate in a series of aqueous solutions purged with an inert gas to remove oxygen thereby avoiding corrosion of the main pole. Initially, the substrate is soaked and heated in deionized (DI) water. Once heated, the substrate is immersed in an etching bath at about 80° C. and pH 10.5. Bath chemistry is preferably based on Na2CO3 and NaHCO3, and N2 purging improves etch uniformity and reduces residue. Thereafter, the substrate is rinsed in a second DI water bath between room temperature and 80° C., and finally subjected to a quick dump rinse before drying. Inert gas, preferably N2, may be introduced into the aqueous solutions through a purge board having a plurality of openings and positioned proximate to the bottom of a bath container.
US08603345B2	Devices for component removal during blood collection, and uses thereof The invention relates to a device and method for collecting blood whereby certain target components are isolated or removed from the blood sample at the time of collecting the blood, as well as methods for using such devices.
US08603344B2	Method and apparatus for removing metal from waste water The present invention has an object to provide a method and an apparatus for removing metals in waste water, such as thallium contained in waste water generated by rinsing waste containing chlorine, ash obtained by burning garbage, fly ash, etc. and reduces the concentration of metals in the waste water to a discharge standard, and the present invention provides a method for removing metals comprising applying direct-current electricity by an electrolyzer 5 to waste water S5, which contains metal aggregate, discharged via a reaction tank 1, a settler 2, and a reaction tank 4, and thereby the waste water S5 is electrolyzed together with depositing metals dissolve in the waste water S5 as metal oxides, separating the waste water containing deposited metal oxides in a precision filtration apparatus 6 into suspended solid MP and waste water S7, and removing a small amount of metals dissolve in the waste water S7 after removing the suspended solid MP in an ion exchange unit 7.
US08603337B1	Lightweight device for heating and purifying water A water heater and purifier has a membrane element and employs an exothermic and pressure-generating chemical reaction. The exothermic reaction heats water, and the gaseous reaction products pressurize an enclosure and force water through a membrane filter for purification. Disinfection of the water is achieved using heat, filtration, and optionally a chemical disinfectant.
US08603335B2	Filter with ejection mechanism A filter system having a filter element ejection device is provided. Filter systems according to the present invention may include a filter element that includes an ejection receiver for receiving actuation action from an ejector of a filter housing. The ejector engages the ejection receiver when a user desires to eject the filter element from the filter housing. Typically, the ejector extends through the filter housing and axially ejects the filter element from the housing.
US08603333B2	Treatment of fluids with wave energy from a carbon arc A method of and apparatus for treating liquids flowing in a thin film around a source of wave energy to directly expose the liquid to the wave energy, preferably generated in whole or part by an electrical arc between carbon electrodes. In addition to the wave energy generated by the electrical arc, energy generated by cavitation of the flowing liquid may be used in treating the liquid.
US08603331B1	Swimming pool chlorination apparatus A tee shaped housing for a swimming pool chlorinator apparatus has three ports, a water inflow port, a water outflow port, and a port into which an electrode assembly unit is sealingly disposed. The electrode assembly includes a plurality of alternating anode and cathode plates which extend into the flow of water in the housing, and the plurality of plates is connected to a source of electrical current. When the electrode assembly is removed for cleaning, a dummy plug is inserted into the port to seal the port so that the flow of water through the housing may continue while the plates are being cleaned.
US08603328B2	Carbon dioxide corn germ oil extraction system Supercritical carbon dioxide extraction of corn germ oil from corn germ utilizing extraction conditions adapted to a dry corn fractionation ethanol production process.
US08603322B2	Method for quantifying a chemical substance by a substitutional stripping voltammetry technique The purpose of the invention is to provide a method for accurately quantifying a chemical substance by a substitutional stripping voltammetry technique. A method is provided for quantifying a chemical substance contained in a sample solution, and the method comprises preparing a measurement system. The measurement system comprises a pair of working electrodes (a first and a second electrodes), a counter electrode, and a gel-coated electrode. This gel-coated electrode comprises an electrode surface, a stripping gel, and a protection gel, and the protection gel covers the stripping gel.
US08603319B2	Methods and systems for removing materials from microfeature workpieces with organic and/or non-aqueous electrolytic media Methods and systems for removing materials from microfeature workpieces are disclosed. A method in accordance with one embodiment of the invention includes providing a microfeature workpiece having a substrate material and a conductive material that includes a refractory metal (e.g., tantalum, tantalum nitride, titanium, and/or titanium nitride). First and second electrodes are positioned in electrical communication with the conductive material via a generally organic and/or non-aqueous electrolytic medium. At least one of the electrodes is spaced apart from the workpiece. At least a portion of the conductive material is removed by passing an electrical current along an electrical path that includes the first electrode, the electrolytic medium, and the second electrode. Electrolytically removing the conductive material can reduce the downforce applied to the workpiece.
US08603314B2	Electrochemical etching of semiconductors Semiconductors are electrochemically etched in solutions containing sources of bifluoride and nickel ions. The electrochemical etching may form pores in the surface of the semiconductor in the nanometer range. The etched semiconductor is then nickel plated.
US08603313B2	Electrode configurations for coating interior and exterior surfaces of conductive substrates in an electrodeposition coating process An electrode assembly for use in electrophoretically depositing an electrodepositable coating composition onto a conductive substrate having a hollowed interior region therewithin includes a first counter electrode and an electrode assembly comprising a second counter electrode and a deployable primary electrode which are introduced within the hollowed out interior region during the electrodeposition process to provide a deposited electrodeposition coating on inner and outer surfaces.
US08603310B2	Gas-concentration/humidity detection apparatus A sensor control apparatus (3) includes a full-range gas sensor composed of an oxygen concentration detection cell having a pair of electrodes (21, 22) and an oxygen pump cell having a pair of electrodes (19, 20). In an electric circuit section (30), an Ip current flowing between the electrodes (19, 20) is controlled such that an electromotive force Vs produced between the electrodes (21, 22) becomes equal to a reference voltage. The reference voltage is usually set to a first reference voltage. However, when the subject gas is air, the reference voltage is set to a second reference voltage. Humidity of the subject gas is detected on the basis of an error ΔIp between an Ip current detected when the reference voltage is set to the first reference voltage, and an Ip current detected when the reference voltage is set to the second reference voltage.
US08603309B2	Disposable sensor for electrochemical detection of hemoglobin A disposable biosensor for determining the content of hemoglobin and hematocrit in a sample of whole blood that includes a laminated strip with a first and second end, at least a reference, a working electrode and a blank electrode embedded in the laminated strip. The working electrode contains a reagent sensitive to hemoglobin or hemotocrit. The blank electrode is used to measure oxidizable species in the fluid sample and to correct the current signal of the working electrode. The construction of the biosensor allows accurate measurement of the impedance of a small fluid sample, which is used to further correct the current signal of the working electrode.
US08603303B2	Nanopore based device for cutting long DNA molecules into fragments Apparatus, system, and method are provided for cutting a linear charged polymer inside a nanopore. A first voltage is applied to create an electric field in a first direction. A second voltage is applied to create an electric field in a second direction, and the first direction is opposite to the second direction. When the electric field in the first direction and the electric field in the second direction are applied to a linear charged polymer inside a nanopore, the linear charged polymer is cut at a location with predetermined accuracy.
US08603302B2	Photocatalytic material, method of decomposing organic substance, interior member, air cleaning device, and device for producing oxidizing agent A divalent copper salt and/or trivalent iron salt is supported on a surface of a metal ion-doped titanium oxide obtained by doping titanium oxide with metal ions to give a metal ion-doped titanium oxide with a valence band potential of 3 V or more (vs. SHE, pH=0) and a bandgap of 3 V or less between the valence band and an energy level of electrons excited from the valence band (including conduction band minimum potential and isolated potential). The metal ion-doped titanium oxide can be made to exhibit strong oxidative decomposition activity when irradiated with visible light based on the fact the divalent copper salt or trivalent iron salt functions as a catalyst for multi-electron reduction of oxygen.
US08603300B2	Fuel fractionation using membrane distillation A method for fractionating a fuel includes heating the fuel and flowing it through hollow superhydrophobic membranes in a membrane module. Vapor from the fuel permeates the hydrophobic membranes and enters a distillate collection chamber, producing distilled fuel and residual fuel. The residual fuel is removed from the module and cooled. The cooled residual fuel is flowed through hollow tubes in the module and the distilled fuel is removed from the distillate collection chamber. Burning the distilled fuel reduces engine emissions. A fuel fractionation system includes a distillate collection chamber, hollow superhydrophobic membranes, hollow tubes and a distillate outlet. The hollow superhydrophobic membranes receive heated fuel and allow vapor from the heated fuel to permeate the membranes and enter the distillate collection chamber. The hollow tubes receive cooled residual fuel and are positioned to allow vapor in the distillate collection chamber to condense on outer surfaces of the hollow tubes.
US08603294B2	Method for stripping a wafer from a carrier Method for stripping a wafer from a carrier that is connected to the wafer by an interconnect layer. The method includes the steps of accommodating the carrier-wafer combination on a receiving means, breaking the connection provided by the interconnect layer by a connection release means, and stripping the wafer from the carrier, or stripping the carrier from the wafer by stripping means.
US08603293B2	Plasma processing apparatus and method A plasma processing apparatus includes a processing container, an exhaust unit, an exhaust plate, an RF power application unit connected to a second electrode but not connected to the first electrode and configured to apply an RF power with a single frequency, the second electrode being connected to no power supply that applies an RF power other than the RF power with the single frequency, a DC power supply connected to the first electrode but not connected to the second electrode, the first electrode being connected to no power supply that applies an RF power, and a conductive member within the process container grounded to release through plasma a current caused by the DC voltage, the conductive member supported by the first shield part and laterally protruding therefrom only at a position that is located, in a height-wise direction, between a mount face and the exhaust plate and below a bottom of a focus ring.
US08603292B2	Quartz window for a degas chamber A five-sided quartz window configured to be mounted on a degas chamber as a UV-transmissive window. The quartz window is made of synthetic quartz and has a uniform thickness. The shape of the quartz window is defined by an upper surface, a lower surface and a sidewall therebetween. The sidewall has five straight sections interconnected by five arcuate sections. The quartz window has four arcuate recesses extending into the sidewall.
US08603288B2	Planarization treatment of pressure sensitive adhesive for rigid-to-rigid substrate lamination The present invention is a process for performing a planarization treatment of pressure-sensitive adhesive (PSA). The process includes positioning a first substrate onto a support surface of a planarization tool. The process further includes placing at least one layer of PSA onto the first substrate. The process further includes positioning a second substrate onto the layer(s) of PSA. The process further includes applying a pressure to the second substrate via a flexible membrane, said pressure being applied in a generally uniform, unidirectional and localized manner. Further, the applied pressure flattens the PSA between the first substrate and the second substrate for promoting suitability of the PSA for use in rigid-to-rigid lamination processes.
US08603286B2	Mechanical part and manufacturing method for the same Reliability of a mechanical part including two parts fixed to each other by an anaerobic adhesive is improved, at least one of the two parts being made of a resin material. After UV treatment is performed on an adhesive surface (10) with respect to a bracket (6) of an outer peripheral surface (7a1) of a housing (7) made of the resin material, the housing (7) is fixed to the bracket (6) by the anaerobic adhesive, whereby an adhesive strength per unit area of 8 N/mm2 or more is obtained for both parts. The UV treatment is performed by irradiating an electromagnetic wave, of an electromagnetic wave irradiated from a light source (11), transmitted through an infrared cut filter (12) having a transmittance of 50% or more and 80% or less in an electromagnetic wave having a wavelength of 254 nm, onto the adhesive surface (10) of the housing (7).
US08603282B2	Adhesive element for adhesion tests and corresponding testing process An adhesive element for adhesion tests, comprising a bi-adhesive layer including a first adhesive surface, designed to co-operate in a relation of adhesion with a surface undergoing testing, and a second adhesive surface. The adhesive element further comprises a support layer having a comparative adhesion surface designed to co-operate in a relation of adhesion with the second adhesive surface. The bi-adhesive layer has a fragmented structure.
US08603276B2	Machine for producing a cup The invention relates to a machine (1) and a method for producing a cup (100) from an outer shell (101) and inner cup (102). For this purpose, the machine (1) comprises a plurality of first holding devices (2) that are arranged on a first rotatably housed star- or wheel-like holding device carrier (3), and a plurality of second holding devices (4), arranged on a second rotatably housed star- or wheel-like holding device carrier (5). Further, a first working station arranged at least in the region of the first holding devices (2) for carrying out working steps (A1 . . . A4) and at least one second working station arranged in the region of the second holding devices (4) for carrying out working steps (B1 . . . B5) are provided. Finally, the machine (1) comprises a transfer station (6) for transferring (A4, B1) a finished outer shell (101) from a first holding device (2) to a second holding device (4).
US08603275B2	Process and apparatus for manufacturing pneumatic tyres In a process of manufacturing pneumatic tires, a carcass sleeve is made which includes at least one carcass ply provided with axially opposite flaps turned up around annular anchoring structures, so as to form respective loops. An outer sleeve is positioned around the carcass sleeve and the latter is radially expanded in order to cause application of same against a radially internal surface of the outer sleeve. After each of the end flaps has been turned up and before radial expansion, only a portion belonging to each of the loops and extending substantially parallel to the respective annular anchoring structure is submitted to a step of carrying out heating under pressure, to make each loop integral with the annular anchoring structure and prevent the turned-up ply/plies from even partly slipping off, during the subsequent radial-expansion step of the carcass sleeve and vulcanization step of the tire.
US08603271B2	Method and device for mixing and initiating a pyrotechnic charge Method and device for mixing and initiating a pyrotechnic charge, comprising at least one coherent porous fuel structure (16) and at least one oxidizer (8). According to the invention, the coherent porous fuel structure (16) and the oxidizer (8) are placed apart in a mixing device (1, 20) to prevent unintentional ignition, and in which the oxidizer (8), in response to the action of a force upon the mixing device (1, 20), for example upon firing of an artillery shell, is transported into the coherent porous fuel structure (16), after which the obtained pyrotechnic charge is initiated after a set time delay.
US08603269B2	Method of fabrication of corrosion resistant oil field tubulars A corrosion resistant waste-water disposal or chemical injection screen is fabricated from extruded, double cold pilgered N06625 or N07716 nickel alloy in a standard oilfield tubular length. After providing each end with a premium thread for a box and a pin end, and slotting the body of the well screen with slits no wider than 0.015 inches and no longer than 2.5 inches, the well screen is ready for deployment in a well. Other types of oilfield tubulars in standard OCTG lengths could be fabricated in the manner described herein.
US08603265B2	Ni-based alloy high-chrome steel structure and manufacturing method of the same There are provided an Ni-based alloy high-chrome steel structure and its manufacturing method capable of joining Ni-based alloys and high-chrome steels by welding, and performing suitable heat treatment, thereby maintaining the strength in the joints. In a manufacturing method of a structure formed by joining together at least two first members formed from Ni-based alloys by welding, and joining a second member formed from high-chrome steels to a member where the first members have been joined together, the manufacturing method includes the steps: joining together the at least two first members formed from Ni-based alloys by welding; performing first-stage aging treatment on a welded joint between the first members, and then, joining the second member formed from high-chrome steels to the member where the first members have been joined together by welding; and then, performing second-stage aging treatment on the welded joint between the first members, and performing heat treatment after welding on a welded portion between the first members and the second member.
US08603262B2	Cleaning apparatus and method of cleaning a structure A cleaning apparatus may include a flow source such as a fan which creates air flow through a ventilation duct or other structure to be cleaned. A projectile source projects projectiles such as dry ice pellets proximate the structure to dislodge debris particles therefrom and introduce the dislodged debris particles into the air flow. An electrostatic precipitator removes the particles from the air flow. An upstream sensor may be used to detect the particles upstream of the electrostatic precipitator and determine if the structure is clean using a controller. A downstream sensor may be used to detect the particles downstream of the electrostatic precipitator and determine the efficiency of the electrostatic precipitator using the controller. Carbon dioxide within the air flow may also be detected.
US08603253B2	Photovoltaic back contact A method to preparing Cadmium telluride surface before forming metal back contact is disclosed. The method can include removing carbon from Cadmium telluride surface.
US08603252B2	Cleaning of semiconductor processing systems A method and apparatus for cleaning residue from components of semiconductor processing systems used in the fabrication of microelectronic devices. To effectively remove residue, the components are contacted with a gas-phase reactive material for sufficient time and under sufficient conditions to at least partially remove the residue. When the residue and the material from which the components are constructed are different, the gas-phase reactive material is selectively reactive with the residue and minimally reactive with the materials from which the components of the ion implanter are constructed. When the residue and the material from which the components are constructed is the same, then the gas-phase reactive material may be reactive with both the residue and the component part. Particularly preferred gas-phase reactive materials utilized comprise gaseous compounds such as XeF2, XeF4, XeF6, NF3, IF5, IF7, SF6, C2F6, F2, CF4, KrF2, Cl2, HCl, ClF3, ClO2, N2F4, N2F2, N3F, NFH2, NH2F, HOBr, Br2, C3F8, C4F8, C5F8, CHF3, CH2F2, CH3F, COF2, HF, C2HF5, C2H2F4, C2H3F3, C2H4F2, C2H5F, C3F6, and organochlorides such as COCl2, CCl4, CHCl3, CH2Cl2 and CH3Cl.
US08603250B2	System and method for deposition of a material on a substrate A method and apparatus for improving coating of a substrate.
US08603249B2	Lift pin driving device and manufacturing apparatus having same A lift pin driving device and a manufacturing apparatus having the device are provided. The device includes drive unit including a single drive motor that drives a pin plate, a plurality of timing belts and a plurality of pulleys. The pin plate, which supports a plurality of lift pins thereon, is moved by the pulleys, operated in conjunction with the motor through the timing belts. A tensioner controls a tension of the timing belts. The tensioner may be controlled to provide precise rectilinear movement without leaning, and to prevent the timing belts from sagging. The device efficiently controls the tension of the timing belts and allows the lift pins to be precisely moved upwards or downwards such that a substrate positioned thereon may maintain a horizontal position while being moved upwards or downwards.
US08603246B2	Growth reactor systems and methods for low-temperature synthesis of nanowires A method for synthesis of silicon nanowires provides a growth reactor having a decomposition zone and a deposition zone. A precursor gas introduced into the decomposition zone is disassociated to form an activated species that reacts with catalyst materials located in the deposition zone to deposit nano-structured materials on a low melting point temperature substrate in the deposition zone. A decomposition temperature in the decomposition zone is greater than a melting point temperature of the low melting point temperature substrate. The silicon nanowire are grown directly on the low melting point temperature substrate in the deposition zone to prevent the higher temperatures in the decomposition zone from damaging the molecular structure and/or integrity of the lower melting point temperature substrate located in the deposition zone.
US08603243B2	Tracking carbon to silicon ratio in situ during silicon carbide growth A method of: supplying sources of carbon and silicon into a chemical vapor deposition chamber; collecting exhaust gases from the chamber; performing mass spectrometry on the exhaust gases; and correlating a partial pressure of a carbon species in the exhaust gases to a carbon:silicon ratio in the chamber.
US08603240B2	Converting coal ash and electric arc furnace dust into glass-ceramic materials A process for control melting a mixture of coal ash, electric arc furnace dust, recycled glass and additives to create a feedstock. The feedstock is quenched or air dried in a mold to create useful products, such as fracking compounds, abrasives, construction products, building materials, landscaping materials, and the like.
US08603239B2	Fiber cement building materials with low density additives This invention relates to a formulation with the addition of low density additives of volcanic ash, hollow ceramic microspheres or a combination of microspheres and volcanic ash or other low density additives into cementitious cellulose fiber reinforced building materials. This formulation is advantageously lightweight or low density compared as compared to current fiber cement products without the increased moisture expansion and freeze-thaw degradation usually associated with the addition of lightweight inorganic materials to fiber cement mixes. The low density additives also give the material improved thermal dimensional stability.
US08603232B2	Water-based ink set for ink-jet recording, ink-jet recording method, and ink-jet recording apparatus There is provided a water-based ink set for ink-jet recording, including: a water-based yellow ink which contains water, a water-soluble organic solvent and a yellow colorant containing a yellow dye (Y-1) and a yellow dye (Y-2) indicated below; a water-based magenta ink which contains water, a water-soluble organic solvent and a magenta colorant containing a magenta dye (M-1) and a magenta dye (M-2) indicated below; a water-based cyan ink which contains water, a water-soluble organic solvent and a cyan colorant containing a cyan dye (C-1) indicated below; and a water-based black ink which contains water, a water-soluble organic solvent and a black colorant containing carbon black.
US08603230B2	Indoor unit of air conditioner An indoor unit (1) is provided with an output control portion (35, 71) for controlling a cleaning signal output portion (33, 48) to output a cleaning signal when it is determined that the amount of dust in a dust storing portion (60, 90) has reached a predetermined first level, and when it is determined that the amount of dust in the dust storing portion (60, 90) has reached a second level that is higher than the first level.
US08603229B2	Multi-element structured arrays (MESA's) for cost effective and high efficiency treatment of fluids Multi-Element Structured Arrays (MESAs) present an effective approach to utilizing high pressure drop media that previously were cost prohibitive for use in a traditional filter element. The operational velocity is significantly slowed by the incorporation of numerous elements; thus, eliminating the Darcian flow resistances of the media. The MESAs are readily fitted with two or more replaceable “filter elements” that are able to employ commercially available media, microfibrous entrapped catalyst/sorbent media, unique multilayers and more. A model capable of estimating pressure drop for flow through a pleated filter is able to be used as a design tool to predict minimum initial pressure drop, maximum filtration area, and preferred media properties with respect to permeability versus thickness thus allowing the filtration system's dirt holding capacity, filtration efficiency and operational energy cost and filtration operational and total ownership costs such as blower energy, filter procurement and shipping, maintenance personnel, filter disposal, inventory and storage, cost of money and more to be improved.
US08603228B2	Power management systems and methods for use in an oxygen concentrator Described herein are various embodiments of an oxygen concentrator system In some embodiment, an oxygen concentrator system includes improved charging and battery control circuits.
US08603225B2	Aluminum naphthalenedicarboxylate as porous metal-organic framework material The present invention relates to a porous metal-organic framework material comprising a bidentate organic compound bound by coordination to a metal ion, the metal ion being AlIII and the bidentate organic compound being 2,6-naphthalenedicarboxylate, wherein the X-ray diffractogram (XRD) of the framework material has a first reflection in the range from 6.5°<2Θ<7.5° and a second reflection in the range from 13.8°<2Θ<15.0°, the area of the first reflection being greatest in relation to the area of all reflections in the range from 2°<2Θ<70° and the area of the second reflection being second greatest, and the sum of the areas of the first and second reflections giving at least 50% in relation to the total area of all reflections in the range from 2°<2Θ<70°. The invention further relates to shaped bodies comprising such a framework material, processes for production of the framework material and also to the use of the framework material or of the proposed shaped body.
US08603223B2	Desalination system and method A water desalination system including at least one pair of evaporators, said pair including a high pressure and a low pressure evaporator, each for evaporating saline water to produce water vapor; at least three adsorption beds in selective vapor communication with each evaporator, said adsorption beds arranged to reversibly adsorb the water vapor from the corresponding evaporator; said adsorption beds in selective vapor communication with a condenser, and in heat transfer communication with a heat source for selectively desorbing the adsorbed water vapor; said condenser arranged to condense the water vapor to desalinated water; wherein said system is arranged to sequentially connect, for a pre-determined period, each evaporator to a corresponding adsorption bed, and the heat source to the third bed.
US08603220B2	Pressure swing adsorption system with indexed rotatable multi-port valves Pressure swing adsorption system comprising two or more vessels, each having a feed end, a product end, and adsorbent material adapted to adsorb one or more components from a multi-component feed gas mixture; piping adapted to (1) introduce the feed gas mixture into the feed ends, withdraw a product gas from the product ends, and withdraw a waste gas from the feed ends of the vessels, and (2) place the product ends of any pair of vessels in flow communication; a feed pipe adapted to supply the feed gas mixture to the system; a product pipe adapted to withdraw the product gas from the system; and a waste gas pipe adapted to withdraw the waste gas from the system. An indexed rotatable multi-port valve is adapted to place the product end of each vessel in sequential flow communication with the product end of each of the other vessels.
US08603205B2	Droplet impingement chemical reactors and methods of processing fuel Fuel processors, methods of using fuel processors, and the like, are disclosed.
US08603200B2	Compositions comprising combustion improvers and methods of use thereof The present disclosure relates to a gasoline combustion improver comprising an organic nitro compound with C—NO2 bond dissociation energy of about 60 to about 80 Kcal/mol of compound, wherein the organic nitro compound is selected from the group consisting of nitro-aromatics, heteroatom aromatic ring compounds, heteroatom nonaromatic ring compounds, and nitrated furfuryls, and wherein the organic nitro compound is not nitrotoluene or dinitrotoluene.
US08603199B2	Method to upgrade bio-oils to fuel and bio-crude This invention relates to a method and device to produce esterified, olefinated/esterified, or thermochemolytic reacted bio-oils as fuels. The olefinated/esterified product may be utilized as a biocrude for input to a refinery, either alone or in combination with petroleum crude oils. The bio-oil esterification reaction is catalyzed by addition of alcohol and acid catalyst. The olefination/esterification reaction is catalyzed by addition of resin acid or other heterogeneous catalyst to catalyze olefins added to previously etherified bio-oil; the olefins and alcohol may also be simultaneously combined and catalyzed by addition of resin acid or other heterogeneous catalyst to produce the olefinated/esterified product.
US08603198B2	Process for producing biodiesel through lower molecular weight alcohol-targeted cavitation A method for producing fatty acid alkyl esters from biolipids through transesterification and/or esterification reactions uses a flow-through cavitation device for generating cavitation bubbles in a fluidic reaction medium. The fluidic medium is passed through sequential compartments in the cavitation device having varying diameters and inner surface features to create localized reductions in fluid pressure thus vaporizing volatile alcohols and creating an increased surface area and optimized conditions for the reaction to occur at the gas-liquid interface around the bubbles.
US08603197B2	Wax compositions and methods of preparing wax compositions Described are morphology stable wax compositions comprising the (trans)esterification product of a wax-forming composition comprising: (a) a triglyceride stock, a fatty acid stock, or a mixture thereof; and (b) a glycerol-based composition comprising glycerol, polyglycerol, or a mixture thereof. Methods of making the waxes are also described. The wax compositions may be used in candles, stack waxes, jell candles, cosmetics, food coatings, adhesives, board manufacturing (e.g., particle board and oriented strand board), urethane foams or coatings, alkyd coatings, coating formulation additives, printing additives, polymer processing agents, extrusion processing aids, polymer plasticizers, mold releases, polishes, and stick markers.
US08603194B2	Battery, manufacturing method of battery, and check method of electrolyte leakage There is provided manufacturing method of battery comprising adhering process (S1) to adhere fluorescent material (leakage indicator including fluorescein) which emits fluorescence in response to predetermined light (ultraviolet radiation) irradiated under condition that electrolyte exists, to at least one portion of a surface on a battery case, and leakage detecting process (S2 through S9) to detect presence/absence of electrolyte leakage with fluorescence which an adhered portion emits in response to the predetermined light (ultraviolet radiation) irradiated on at least the adhered portion which has adhesion of the fluorescent material (leakage indicator including fluorescein), out of the surface on the battery case.
US08603193B2	Method for producing prismatic secondary cell A method for producing a prismatic secondary cell housing a flat electrode assembly includes disposing a first current-collecting member onto a first to-be-welded portion at a flat portion of an edge of the electrode assembly where a core-body exposed portion of the first electrode protrudes. A first receiving member is disposed onto a plane opposing the flat portion. The first current-collecting member, the core-body exposed portion, and the first receiving member are resistive-welded with the core-body exposed portion between the other members. A second current-collecting member is disposed onto a second to-be-welded portion at a position of the flat portion distanced from the first to-be-welded portion while avoiding contact between the collecting members. A conductive connecting member is placed between the collecting members or between the receiving members. The conductive connecting member and its abutting members are welded. One of the members is electrificably connected to an external output terminal.
US08603191B2	Azo compound, aqueous solution, ink composition, ink for inkjet recording, inkjet recording method, ink cartridge for inkjet recording, and inkjet record There is provided an aqueous solution containing (a) a preservative and (b) at least one azo compound represented by the following Formula (1) or a salt thereof, in which the content of (b) is 1% by mass to 25% by mass. (In Formula (1), G represents a nitrogen atom or —C(R2)═. R2 represents a hydrogen atom, a sulfo group, a carboxyl group, a substituted or unsubstituted carbamoyl group or a cyano group. X1, X2, X3, X4, X5, X6 and X7 each independently represents a hydrogen atom or a monovalent substituent. Y2, Y3 and Y4 each independently represents a hydrogen atom or a monovalent substituent. Y2, Y3 and Y4 may be bonded with each other to form a ring. All of Y2, Y3 and Y4 do not represent hydrogen atoms at the same time. M each independently represents a hydrogen atom or a monovalent countercation.)
US08603188B2	Medical device suitable for treating reflux from a stomach to an oesophagus A medical treatment device (200), for treating reflux from a stomach (201) to an esophagus (202) and for delivering a therapeutic agent to an inner surface of the esophagus (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the esophagus (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the esophagus (202) and the stomach (201). The lining member (204) lines part of the inner surface of the esophagus (202) for delivery of a therapeutic agent to the esophagus (202).
US08603187B2	Device for dilating the urethra of the body of a patient and device for removing prostate tissue Device for removing prostate tissue from within the urethra, the device including a plurality of arms, and an actuating mechanism coupled to the arms, the arms being rotatable about a longitudinal axis of the urethra, the arms being divided into arm pairs, each of the arm pair being apart from each other in a first configuration and attempting to get closer to each other, in a second configuration, wherein the device is inserted in the urethra toward the prostate, in the first configuration, and wherein after the device is placed adjacent to the prostate, within the urethra, the actuating mechanism moves the arms to the second configuration, thereby pinching the prostate through the urethra.
US08603185B2	Stent geometry A non-expandable stent and a method for implanting the stent are provided. The stent includes a generally tubular body having a lumen defined therethrough. The body includes a proximal portion having a curved portion configured for placement proximal to a sphincter. The body further includes a distal portion having retaining member extending outward from a proximal end of the distal portion. The retaining member is configured for placement distal to the sphincter and for engagement of the sphincter.
US08603182B2	Hip prostheses Bipolar prostheses which include various structures and other techniques for optimizing material wear and mechanical strength properties. Such prostheses feature, for example, improved resistance to polyethylene wear while also reducing potential for dislocation of the femoral stem from the prosthesis. Such techniques and structures include varying wear resistance and mechanical strength treatment in various components of the prostheses or portions of those components as desired to improve, accentuate or optimize wear performance and dislocation reduction, locking ring structural features, structures for retaining locking rings in the bipolar prosthesis shell, and structures for limiting or reducing movement or rotation of locking rings and liners in bipolar prosthesis shells.
US08603179B2	Implants for the treatment of osteoarthritis of the knee A replacement knee implant has a femoral implant and a tibial implant, each of which are inset in a bone surface. The tibial implant is generally elongated with one end rounded and an opposite end conforming to the shape of the tibia, and is made of a metal alloy or a ceramic. The upper surface is dished while the lower surface is planar and can be parallel or sloped relative to the upper surface. The femoral implant for implementation in a femoral condyle is rounded such that, when implemented, the femoral implant is flush at the anterior and posterior sides and protruding away from the femur between the anterior and posterior ends. The femoral implant can have an elongated keel for extending into the femur, and can be made from a highly cross-linked polyethylene.
US08603178B2	Knee prostheses with convex portion on tibial lateral articular surface Knee prostheses featuring components that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or at least accommodating internal tibial rotation in a controlled way, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a more natural way. In a preferred embodiment, such prostheses include an insert component disposed between a femoral component and a tibial component, the insert component preferably featuring among other things a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes. Other surfaces can also be specially shaped to achieve similar results, preferably using iterative automated techniques that allow testing and iterative design taking into account a manageable set of major forces acting on the knee during normal functioning, together with information that is known about natural knee joint kinetics and kinematics.
US08603175B2	Method of inserting surgical implant with guiding rail A prosthetic intervertebral spacer includes a body and an interface extending away from the body for use during implantation of the spacer. The interface can be a rail including a neck portion connected to the body and a lip portion connected to the neck portion. The lip portion can be wider than the neck portion in a direction extending between the top and bottom surfaces of the implant. Methods of implanting the spacer and tools used during such procedure are also provided.
US08603174B2	Dynamic spinal implants incorporating cartilage bearing graft material A dynamic spinal implant utilizes cartilage bearing graft material in dynamic disc replacement and/or facet arthroplasty. Methods and apparatus for dynamic spinal implants incorporate bulk articular graft tissues derived from donor joint sources in human (allograft or autograft) or non-human (xenograft) tissue. The donor joint is preferably prepared as a biological dynamic spinal implant with articular cartilage as a bearing interface between adjacent bone surfaces that naturally articulate with respect to one another.
US08603173B2	Space keeper with adjustable axial length A space keeper for insertion between two vertebrae which has a variable axial length is provided. The space keeper possesses a sleeve-like first member (2) and a second member (3) guided in the latter and movable relative to the first member in the axial direction for adjusting an overall length. In order that adjustability during operating is facilitated the two members (2, 3) are connected to one another by a lever (7, 8), wherein one center of motion (16) of the lever is connected to one member (3) and the other center of motion (18) is connected in terms of action to the other member (2).
US08603170B2	Expandable intervertebral implant A method of inserting an expandable intervertebral implant is disclosed. The implant preferably includes first and second members capable of being expanded upon movement of first and second wedges. The first and second wedges, while being capable of moving with respect to each other and the first and second members are also preferably attached to the first and second members. In addition, the first and second wedges are preferably capable of moving only in a first direction, while movement in a second direction is inhibited. The first and second wedges are also preferably prevented from torsionally moving with respect to the first and second members.
US08603167B2	Intra-ocular artificial lens with variable optical strength An intra-ocular artificial lens with variable optical strength, having at least two optical elements, at least two of which are movable relative to each other in a direction extending transversely of the optical axis, wherein the optical elements have a form such that in different positions of the movable optical elements the artificial lens has a different optical strength, wherein the artificial lens has a fixed, positive optical basic strength wherein the variable optical strength caused by the relative movement of the movable elements is added to obtain the total optical strength of the artificial lens. Providing a different form results in the possibility of incorporating the greatest optical power in one of the optical elements. This optical element can then be optimized for the desired optical properties. The remaining optical element or the remaining optical elements can then be dimensioned for variation of the optical strength.
US08603166B2	Intraocular lens assembly Disclosed is an intraocular lens assembly provided inside a capsular sac. The intraocular lens assembly according to one embodiment of the present invention includes an intraocular lens and an intraocular lens supporter, and therefore the intraocular lens assembly may be useful to transfer a force to the intraocular lens, inserted inwardly into the capsular sac, to allow the intraocular lens to move like a natural eye lens, the force being generated from the ciliaris muscle and transferred through the zonule of Zinn and the capsular sac.
US08603159B2	Prosthetic valve for transluminal delivery A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.
US08603158B2	Irradiated stent coating An expandable stent for use within a body passageway having a body member with two ends and a wall surface disposed between the ends. The body member has a first diameter to permit delivery of the body member into a body passageway and a second expanded diameter. The surface of the stent is coated with a biological agent and a polymer which controls the release of the biological agent.
US08603152B2	Devices and methods for vestibular and/or cranial nerve stimulation An in-ear stimulator for administering thermal stimulation to the ear canal of a subject includes (a) an earpiece configured to be insertable into the ear canal of said subject, the earpiece having an outer surface and an internal cavity formed therein, the internal cavity having an inner surface; and (b) at least one thermoelectric device thermally coupled to the earpiece internal cavity inner surface.
US08603151B2	Therapeutic cooling devices A thermal regulatory system to reduce swelling caused by trauma to a variety of tissues and limbs is provided. One or more substantially flexible, at least partially thermally conductive housing containing optionally activatable thermal regulatory medium may be coupled with one or more applicator, such as a splint, that is adapted to apply the medium housing to the tissue. Methods of therapeutically regulating tissue temperature are also provided.
US08603149B2	Method and apparatus for a radiolucent and MRI compatible cranial stabilization pin A substantially radiolucent cranial stabilization pin is adapted for use with a fixture for immobilizing a patient's head during a medical procedure. The pin includes a tip and a body, which are secured together to form the pin. The tip and body are constructed from non-ferrous, non-magnetic materials that are biocompatible. The tip and body are safe for use with, and compatible with, imaging techniques including MR imaging and CT imaging. In some examples the tip is a titanium insert and the body is molded within and around at least a portion of the tip. In some versions, the tip includes a hollow portion and one or more openings providing access to the hollow portion. The molded body flows into and around portions of the tip creating a secure pin suitable to withstand torque and axial forces observed in use.
US08603148B2	System for treating bone fractures According to one embodiment, a bone fixation system includes a plate having a first opening a beam configured to traverse through the first opening and reside proximate to a subchondral fragment of bone in an installed position. The beam may be operable to rotate about an axis of rotation proximate to the first opening and reposition the subchondral fragment of bone.
US08603144B2	Adjustable bone screw assembly A bone screw assembly includes a screw body, including anchor portion and rod-receiving portion, and a rod seat movably mounted in the screw body to allow for controlled angulation between a spinal connection element disposed in the rod seat and the screw body. The rod seat is pivotable in one or more selected directions about one or more axes relative to the screw body. The rod seat may include a first lower rod seat element disposed in a recess of the screw body having a cylindrical bottom surface to facilitate pivoting in a first direction. A second lower rod seat element is stacked on the first lower rod seat element and has a conical bottom surface abutting a top surface of the first lower rod seat element to facilitate pivoting in a second direction.
US08603143B2	Spinous process fixation apparatus An implantable device and method for fixation of spinous processes is presented. The device has first and second spaced plates configured for attachment to portions of adjacent spinous processes. The device can also have an implant configured for insertion between two adjacent spinous processes, but need not necessarily. The method has the steps of assembling the components of the implantable device and otherwise inserting them into position onto, between, and/or adjacent two desired spinous processes.
US08603138B2	Use of an adhesive to treat intraluminal bleeding A surgical device to stanch the flow of blood is disclosed. The surgical device can place an implantable adhesive over or around varices or other bleeders. The surgical device has a vacuum system for capturing tissue and an adhesive system to apply adhesive to the captured tissue. A vacuum chamber is used to contact tissue and contains a chamber therein for the reception of tissue. An adhesive applicator is provided within the vacuum chamber and moves longitudinally therein to apply adhesive to tissue. The surgical device can apply an adhesive patch to tissue or inject adhesive into tissue. Alternately, an adhesive actuator and a chemical agent can be dispensed to tissue within the vacuum chamber.
US08603137B2	Methods and systems for establishing hemostasis relative to a puncture Systems and methods for establishing hemostasis relative to a puncture in a lumen wall. A closure device includes a proximal portion and a distal portion. The proximal portion or distal portion rotates during deployment to either close a puncture or plug a puncture to establish hemostasis. A method includes positioning a closure device in a deployment device, positioning the closure device in the tissue tract, and actuating the deployment device to establish relative rotation between the distal portion and the proximal portion of the closure device.
US08603135B2	Articulating surgical apparatus An endoscopic instrument includes a housing having shaft. The shaft includes an articulating section disposed thereon. The articulating section includes a plurality of annular stationary and rotatable links arranged in an alternating configuration therealong. Each link of the plurality of rotatable links seated within a corresponding stationary link of the plurality of stationary links to collectively define a central annulus therethrough. An end effector assembly operatively connected to a distal end of the shaft includes a pair of first and second jaw members. An articulation catheter operably disposed through the central annulus is configured to rotate the rotatable links with respect to the stationary links to articulate the shaft about the articulating section.
US08603134B2	Latch mechanism for surgical instruments A surgical instrument includes a pair of jaw members moveable between a spaced-apart and an approximated position. A drive bar is translatable between a distal and a proximal position for moving the jaw members between the spaced-apart and approximated positions. A lever is moveable between an initial position and an actuated position for translating the drive bar between the distal and proximal positions. A sleeve disposed about the drive bar includes an annular track having a substantially radial segment(s) and a substantially longitudinal segment(s). A collar interdisposed between the sleeve and the drive bar includes a stop member(s) extending radially outwardly therefrom. The stop member(s) is engaged within the track and is translatable from a first position, wherein the stop member is positioned within the longitudinal segment, to a second position, wherein the stop member is engaged within the radial segment, to lock the lever in the actuated position.
US08603133B2	Medical instrument The invention relates to a medical instrument having a hollow shaft, a tool positioned on the distal end of the shaft consisting of a rigid jaw member and a jaw member that can rotate with respect to the rigid jaw member, as well as a handle positioned on the proximal end of the shaft. The tool and the handle are in active connection with one another by a push-pull rod mounted in the shaft, and the jaw members of the tool are mounted on one another by pins. It is proposed with the invention that the push-pull rod should be configured as a hollow slide tube mounted in the shaft so that it can slide axially and is in active connection with the rotatable jaw member by an actuation element that is essentially rod-shaped.
US08603132B2	System and method for providing embolic protection An apparatus for offering embolic protection is provided that includes a sponge operable to be positioned in an area of a patient who is to undergo a cardiovascular procedure. The sponge is operable to collect debris present in or proximate to the area and to allow a portion of blood flow or no blood flow associated with the area to continue while the debris is collected.
US08603130B2	Instrument for engaging a body structure An instrument for engaging an underlying blood vessel or body structure. The instrument comprises a pair of instrument arms, and an instrument finger extends at an angle from each arm. The distal end of each instrument finger comprises a bottom surface at an angle to the axis of the instrument finger such that it is adapted to rest upon the underlying blood vessel or body structure. In certain embodiments the bottom surfaces are in a plane that is substantially parallel to the plane of the instrument arms.
US08603127B2	Removable anchored lung volume reduction devices and methods An intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.
US08603121B2	Systems and methods for creating anastomoses Medical system and methods are provided for forming an Anastomosis, such as an intestinal bypass anastomosis for treatment of obesity or diabetes. The medical devices and methods are minimally invasive and reduce complications. One embodiment of the method includes forming a first opening in the first section and forming a second opening in the first section. A proximal portion of the second section is moved to a position adjacent the first opening, and a distal portion of the second section is moved to a position adjacent the second opening. In this manner, an intermediate portion of the second section extends along the first section and an anastomosis can then be formed between the first section and the second section.
US08603110B2	Organism tissue suturing apparatus An organism tissue suturing apparatus for suturing a penetrated hole formed subcutaneously in a tissue membrane of an organism includes a body part having a predetermined length. The body part includes a rotary portion, disposed at a front end thereof, that can be inserted into the tissue of the organism from the hole, a needle member accommodated in a portion, inside the body part, rearward from the rotary position, and a pressing mechanism for advancing the needle member from a side surface of the body part and pressing the needle member into the rotary portion. The rotary portion has a needle member receiving portion for receiving essentially a front end of the needle member pressed into the rotary portion by the pressing mechanism, with the rotary portion disposed in the tissue of the organism. The needle member has a suturing thread of a duct for the suturing thread.
US08603101B2	Provisional tibial prosthesis system The present disclosure provides a provisional tibial prosthesis system for a set of prosthetic knee joints for implantation in a natural knee, the provisional tibial prosthesis system including a bearing component and a bearing support, the spacing of the bearing component from the bearing support is adjustable to allow for representation of a variety of different sized final tibial prostheses. In this system, only one provisional bearing component corresponding to each level of constraint is needed and shims are used to adjust the spacing of the bearing component from the bearing support. The shims are slidably insertable between the bearing component and the bearing support in an anterior/posterior direction to allow for adjustment of the spacing of the bearing component from the bearing support. The number of provisional components needed during knee surgery is reduced and adjustment of the system only requires the knee joint to be distracted by a distance equal to the height of a particular shim.
US08603099B2	Force dissipating impactor device A method of assembling an implant in one embodiment includes aligning the connection features of a first implant component with the connection features of a second an implant component, placing an implant engagement surface of an impactor device and the first implant component in contact, striking an impaction surface of the impactor device, transferring force from the impaction surface to an impactor shaft, diverting the transferred force within the shaft, focusing a portion of the diverted force, and transferring the focused force from the shaft to the first implant component which brings the connection features on the first implant component into engagement with the connection features on the second implant component.
US08603097B2	Minimally invasive surgical applicator The present invention provides a minimally invasive surgical applicator device. The device is useful in the application of bone wax during surgical procedures to halt or reduce bone bleeding. The device may be sterilized for re-use or may be made disposable.
US08603095B2	Apparatuses for femoral and tibial resection Systems for use in total knee arthroplasty include a cutting guide having only a single slot. The single slot is configured to be positioned adjacent an anterior side of the medial compartment of the knee joint with no portion positioned adjacent an anterior side of the lateral compartment of the knee joint. The single slot is adapted to guide an oscillating saw blade across the knee bone from the medial compartment to resect at least a portion of the lateral compartment. The system also includes a total knee arthroplasty implant adapted to be implanted on the resected surface.
US08603094B2	Minimally invasive surgical tower access devices and related methods Devices and methods are provided for assisting in spinal stabilization. An access device is provided that includes an outer sleeve, inner sleeve, spring latch and lock nut. The inner sleeve includes compressible grasping elements. The access device can be coupled to a screw head by sliding the outer sleeve relative to the inner sleeve and compressing the grasping elements. The coupled access device and screw can then be delivered to a target location in a patient. After providing two or more access devices, a rod member can be delivered using a rod insertion device. The rod member can serve as a connection between the two screws, and can provide spinal stabilization. An anti-torque device and a persuading device can be used to help ensure that the rod member is placed and secured in a proper location within a patient.
US08603091B2	Pelvic and scapular bone plate and method for implantation The invention relates to a pelvic or scapular bone plate implant having a planar or curved outer frame portion. The frame has a surface which can be aligned with a surface of a bone to which the bone plate is to be implanted. The plate has a flap portion, the outer frame portion at least partially surrounds the flap portion such that the bone contacting surface the flap portion is located within the outer boundary of the frame portion. The flap portion is connected with the outer frame portion via a material interconnection which allows the flap to be bent with respect to the frame. A method for implanting such a bone plate implant is also taught.
US08603089B2	Surgical instrument including inductively coupled accessory A surgical instrument system includes a surgical instrument, a power supply, and an accessory. The surgical instrument has a first induction device positioned therein. The accessory is selectively operably couplable to the surgical instrument. The accessory includes a second induction device that is inductively coupled with the first induction device when the accessory is operably coupled to the surgical instrument such that the power supply provides power to the accessory.
US08603086B2	Method for preventing thrombus formation The present invention provides devices and methods for preventing or significantly reducing the risk of thrombus formation. More specifically, the devices and methods of the present invention provide energy to blood flowing within a chamber or vessel to prevent or reduce blood stasis and thereby prevent or significantly reduce the risk of thrombus formation. The present invention is ideally suited for prevention or reduction of risk of blood clot formation in the atria in patients with atrial fibrillation, in blood vessels of patients at risk of clot formation, in areas adjacent to, or on, artificial heart valves or other artificial cardiovascular devices, and the like.
US08603085B2	System and method for selectively energizing catheter electrodes The present invention is directed to a system, a method and a catheter that provide improved ablation capabilities and improved energy efficiency by selectively energizing catheter electrodes on the basis of impedance measurements. In particular, the invention is directed to the selective energization of catheter radial electrodes that together with a tip electrode form a generally continuous tissue contact surface, wherein the selection is made on the basis of impedance measurement as an indication of the amount of tissue contact of each radial electrode.
US08603080B1	Non-invasive laser vasectomy The present invention presents novel methods for performing noninvasive vasectomies in animals, including humans, and vasectomy clamps for use in such procedures. The invention further presents an apparatus for use in noninvasive male sterilization procedures. More specifically, the invention presents the application of lasers for noninvasive thermal coagulation and occlusion of the vas. Non-contact cooling of the tissue surface, for example, via cryogen or other cooling spray, prevents scrotal skin burns during the procedure. Both the laser radiation and cooling spray are delivered in a non-contact mode to the tissue. This procedure also preserves the surgical field-of-view, potentially allowing the urologist to visually monitor the skin surface during subsurface heating of the vas and preventing the formation of scrotal skin burns.
US08603078B2	Methods and devices for guiding and supporting surgical instruments Methods and devices are provided for allowing a surgical instrument to be supported by a surgical support system configured to controllably guide the instrument to a desired position at surgical site. A surgical support system is provided that includes a guide port defining a pivot point about which a surgical instrument advance therethrough can pivot. The guide port, and hence the pivot point, can be located a distance above a tissue surface through which the instrument is advanced. Methods and devices are also provided for allowing insufflation of a body cavity without introduction of an insufflation fluid therein. A mechanical insufflation device is provided that includes an expandable distal member configured to selectively expand and unexpand to mechanically insufflate a body cavity. The mechanical insufflation device can optionally be used with the surgical support system.
US08603072B2	Male connector and transfusion line connection apparatus equipped with male connector The male connector of the present disclosure allows for the flow of fluids therethrough and includes a movable blunt needle having a shoulder projecting radially outwards from the movable blunt needle. The male connector also includes an outer cylinder body formed around the movable blunt needle and disposed in coaxial alignment to the movable blunt needle, a blunt needle retainer which retains the movable blunt needle so that the movable blunt needle can move in an axial direction, and a valve which opens as a result of the movable blunt needle moving in the axial direction when the posterior end presses against the valve. This occurs when the movable blunt needle is inserted into a corresponding connection site, such as a female connector, and the shoulder presses against the connection site to force the movable blunt needle in the axial direction.
US08603069B2	Steering mechanism for bi-directional catheter A bi-directional catheter with nearly double the throw in its catheter tip deflection defines a puller wire travel path having a U-turn a pulley which minimizes the offset angle between the puller wire and the longitudinal axis of the control handle while maximizing the travel distance of that puller wire for any given distance traveled by the pulley drawing the puller wire. In particular, the control handle of the catheter which includes a steering assembly having a lever arm carrying a pair of pulleys for drawing corresponding puller wires to deflect the tip section of the catheter. The pulleys are rotatably mounted on opposing portions of the lever arm such that one pulley is moved distally as the other pulley is moved proximally when the lever arm is rotated. Because each puller wire is trained on a respective pulley, rotation of the lever arm causes the pulley that is moved proximally to draw its puller wire to deflect the tip section in the direction of the off-axis lumen in which that puller wire extends.
US08603066B2	Catheter and introducer catheter having torque transfer layer and method of manufacture The instant invention relates generally to catheters and to introducer catheters used to help deliver catheters or other medical devices to locations within the human body. In particular, the instant invention relates to large diameter catheters and introducer catheters having a torque transfer layer that includes at least two flat wires braided into a wire mesh. The flat wires have a width of at least about 0.007 inches and a depth of at least about 0.003 inches. The lumen diameter of the catheter is at least about 6 French. The torque transfer layer provides increased strength, flexibility, and kink resistance.
US08603062B1	Feminine hygienic pad assembly A feminine hygienic pad assembly includes a panel that is configured to absorb and retain fluids. The panel includes a first end section, a second end section and a central section extending between the first and second end sections. The first and second end sections have a circular shape, and the first and second lateral edges of the central section are concavely arcuate. A base member is flexible and has an inner surface and an outer surface. The panel is attached to the inner surface. The base member has a first edge and a second edge positioned opposite of each other. First and second straps each extend between the first and second edges of the base member. The first and second straps are positioned on opposite sides of the base member.
US08603059B2	Stretch laminate, method of making, and absorbent article A stretch laminate includes a first layer including an elastomer film, the first layer having a surface, and a second layer including a nonwoven material, the second layer having a basis weight of less than about 25 gsm and a surface that is attached to the surface of the first layer. The elastomer film has a strength of an engineering tensile strength, at an engineering strain rate of about 600/s, of at least one of about greater than about 14 MPa for a plain specimen or about greater than about 7 MPa for a notched specimen. A method of making the stretch laminate and an absorbent article having at least one region defined by the stretch laminate are also provided.
US08603058B2	Absorbent article having an absorbent structure configured for improved donning and lateral stretch distribution An absorbent article generally has a longitudinal axis, a lateral axis, a front waist region, a back waist region, and a crotch region extending longitudinally between and interconnecting said front and back waist regions. The article comprises an outer cover stretchable in at least the lateral direction and a liner in opposed relationship with the outer cover and stretchable in at least the lateral direction. An absorbent structure is disposed between the liner and the outer cover and extends from the crotch region to at least one of the front waist region and the back waist region of the article. The article has an attachment zone and at least one non-attachment zone laterally adjacent the attachment zone. The absorbent structure is configured for improved lateral stretch distribution of the article.
US08603057B2	Method of controlling the flow of bodily fluid A system and method are disclosed for automatically limiting the drainage of a bodily fluid such as cerebrospinal fluid (CSF) from a patient into a collection chamber. The collection chamber includes a vent having an hydrophobic filter for the passage of air to facilitate the movement of CSF yet to maintain a closed system. The system includes a buoyant float hingedly connected with the top of the collection chamber in one embodiment. When fluid rises in the collection chamber to a predetermined volume, buoyant force raises the float and causes a seal plug mounted on top of the float to seal one of an inflow port or a vent port. The float is limited to pivoting movement in one plane and to a certain angle within that plane. The system and method avoid overdrainage of CSF from the patient and overfilling of the collection chamber.
US08603054B2	Delivery product for topical compositions A delivery product is used to deliver a skin composition to the skin of a user. The delivery product includes a thermo-responsive polymer film. The polymer film is solid at room temperature but, once contacted with the skin, increases in temperature and degrades. A skin composition is associated with the polymer film. The skin composition can be applied to a surface of the film or can be incorporated into the film. The skin composition is released by the polymer film for treating the skin of the user.
US08603050B2	Implantable infusion devices including apparatus for confirming side port access Implantable infusion devices and systems with side port access detection capability and methods of detecting side port access. The methods may include the steps of sensing pressure in a fluid passage between an implanted pump mechanism and an implanted outlet port and determining that an implanted side port has been accessed by a hypodermic needle based on a predetermined change in pressure in the fluid passage between the implanted pump mechanism and the implanted outlet port.
US08603049B2	Atraumatic suction catheter There is provided a suction catheter having a tubular body with a lumen formed therethrough. The catheter has a plurality of spaced elongated apertures positioned near its distal tip. The catheter may have a fourth round opening positioned proximally to the three openings. The catheter has reduced impact force compared to similar suction catheters without the plurality of apertures near the distal tip.
US08603046B2	Automated injection catheter device and system A device and system for automating catheter needle injection has a first actuator that extends a needle past the distal end of the catheter, a second actuator that depresses a plunger to deliver injectate through the needle and an agitator assembly to agitate the injectate before it enters the needle. The device and system may also include a force sensor coupled to the plunger to sense pressure to detect occlusion, and an optical sensor to sense movement of the second actuator.
US08603043B2	Needle sheathing device with flexible end-piece for syringe The invention relates to a safe support device for a syringe, said support comprising a support sheath for the body of a syringe, and safety means which comprise an inner sheath suitable for sliding relative to said support sheath between a waiting retracted position, in which said inner sheath is substantially retracted inside said support sheath, and an active protection position, in which said inner sheath projects from said support sheath. The inner sheath has a free end portion formed by a flexible end-piece. The invention also relates to an assembly comprising such a safe support device and a syringe having a body, a piston and a needle disposed at one end of said body.
US08603042B2	Safety needle device with snap feature and method of making same The present invention safety device is a one-piece needle assembly that has a base and a housing pivotally connected to the base. The base has a distal portion to which a needle is fitted. At the base there is formed longitudinally along its distal portion a catch mechanism that may be in the form of an anchor projection. At the back wall of the housing there is extended another catch mechanism that may be configured in the form of two clasping fingers. Also providing in the housing is an integral hook. As the housing and the base are pivoted relative to each other, and as the needle makes contact with the hook, the respective catch mechanisms at the base and the housing also make contact with each other, resulting in the coupling of the catch mechanisms and the coupling of the needle to the hook. As a result, the catch mechanisms are interlocked and the needle is fixedly retained by the hook within the housing. The catch mechanisms may also be configured as a hook and a latch in the form of a rib with an opening whereto the hook is fixedly coupled. The catch mechanisms may further be configured as respective interlockable pairs of loops and bosses. The gauge of the needle may be determined by the color of both the base and the housing, which are molded as a unitary single unit.
US08603039B2	Syringe protector A syringe protector. The syringe protector includes a clamping member, a guard member, and a retaining member. The clamping member being able to lockably engage the needle guard and allow the passage of a needle therethrough. Insertion of the clamping member into the guard member creates a locking interaction between the toothed surface of the clamping member and a complementary toothed or ribbed surface of the guard member. Further, the clamping member holds a retaining member which acts to secure a syringe body once the needle of the syringe enters the guard member.
US08603036B2	Vascular introducer and method of using same A vascular introducer for accessing a circulatory system of a patient includes a sheath and a dilator. The sheath includes a fitting attached at a proximal end, and includes a liner that is longer than a core tube. A proximal segment of the liner is attached to an inner surface of the core tube, but a distal segment of the liner is everted to cover an outer surface of a distal segment of the core tube. The dilator is positioned in the sheath and includes a tapered distal segment that extends beyond a distal end of the sheath. A handle is attached to the proximal end of the dilator and extends proximally from the fitting. During a procedure, a blood vessel may constrict and grip the sheath. During withdrawal of the sheath, the core tube is slid within a first portion of the everted distal segment of the liner while another portion of the liner is de-everting.
US08603033B2	Medical device and related assembly having an offset element for a piezoelectric speaker A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, other internal components in the housing, and a keypad external to the housing. The device includes a number of features and elements that enhance its operation, manufacturability, reliability, and user-friendliness. These features and elements include a shock absorbing element for a battery of the device, a keypad actuator layer that overlies a keypad assembly and forms a water resistant seal with the housing, and an offset element for a piezoelectric speaker that is located inside the housing.
US08603029B2	Apparatuses and methods for medication administration Apparatuses and methods for medication administration via a body cavity. In one aspect, a medication administration device includes: a tip portion having a plurality of holes and a balloon defining a balloon cavity. When the balloon is deflated the tip portion can be inserted into a body cavity, such as the rectum, to allow medication delivery through the holes in the tip portion. When inflated, the balloon can prevent the tip portion from being withdrawn from the body cavity and/or hold dispersed medication within the body cavity. The device further includes a port portion that has a first port and a second port, and an elongated tubular portion that is coupled between the tip portion and the port portion. The tubular portion has a first lumen connecting the first port to the plurality of holes in the tip portion, and a second lumen connecting the second port to the balloon cavity.
US08603028B2	Injection device having an angled tip portion In one embodiment, the handheld injection device includes a first housing having a first axis and a second housing having a second axis. In one embodiment, the second housing is configured to support a needle. In one embodiment, the first axis and a second axis form an adjustable angle between about 180 degrees and about 90 degrees.
US08603024B2	Glaucoma drainage devices including vario-stable valves and associated systems and methods Glaucoma drainage devices including vario-stable valves and associated systems and methods are disclosed. A glaucoma drainage device includes a drainage lumen and a valve system coupled to the drainage lumen to control the flow of fluid through the drainage lumen. The valve system includes an adjustable valve with a diaphragm that is in communication with the drainage lumen and is movable to occupy varying amounts of the drainage lumen. In some embodiments, the valve system is maintained in a desired position without the use of power such that power is only needed when changing a position of the adjustable valve.
US08603017B2	Vibrational therapy assembly for treating and preventing the onset of deep venous thrombosis A vibrational therapy assembly treating and preventing Deep Venous Thrombosis, and other conditions, using vibrational energy.
US08603013B2	Pressure switches, transmitters, systems, and methods for monitoring a pressure at a tissue site Apparatuses, systems, and methods for monitoring a pressure exerted on a tissue site are provided. In one embodiment, an apparatus includes a pressure switch adapted for placement adjacent the tissue site. The pressure switch includes an antenna operable to receive a first signal, a diode disposed adjacent the antenna, and a membrane covering the antenna and the diode. The membrane is movable from an unpressed position to a pressed position when a force is exerted on the membrane to cause electrical communication between the antenna and the diode. The antenna is operable to send a second signal when the membrane is in the pressed position. The apparatus may also include a transmitter operable to emit the first signal to the antenna. The transmitter may output an alert when the transmitter receives the second signal.
US08603009B2	Flashback blood collection needle A needle assembly includes a transparent or translucent housing with a fluid inlet and outlet end, a flashback chamber, and a venting mechanism therebetween. The venting mechanism includes a blocking member to control the fluid flow in the venting mechanism so that it flows along the longest path through the vent. Substantially axially aligned inlet and outlet cannulas extend from the housing and communicate with the chamber. A sealable sleeve covers the external end of the outlet cannula. Relative volumes of the cannulas, the chamber, and the sleeve are selected to provide rapid reliable flashback indicative of venous entry with an internal vent positioned within the housing to divide the interior into first and second chambers, with the second chamber being adapted to maintain a negative pressure therein relative to the external environment so as to inhibit leakage of blood from the needle tip on withdrawal from the patient.
US08603007B2	Data binning method and system for estimating respiratory airflow from body sound signal Data binning methods and systems for estimating a subject's respiratory airflow from a body sound signal detected by an acoustic sensor on the subject's body. The methods and systems operate in a configuration mode followed by a monitoring mode. In the configuration mode, a body sound signal and respiratory airflow are detected by an on-body acoustic sensor and a spirometer, respectively, over a common time period. Time-aligned body sound signal and respiratory airflow data points are then generated and assigned to bins each spanning a discrete signal range (e.g. discrete signal entropy range or signal amplitude range). Respiratory airflow estimation data (e.g. mean airflow and standard deviation) are then calculated for each bin and an entry for each bin associating the discrete range and the estimation data is stored in a lookup table. Then, in the monitoring mode, the lookup table is accessed using subsequent body sound signal readings (e.g. taken in the field or at home) to provide respiratory airflow estimates without further need for a spirometer.
US08603006B2	Method and apparatus for detecting ineffective inspiratory efforts and improving patient-ventilator interaction A method and system for detecting an ineffective effort of a patient being mechanically ventilated by a ventilator comprises (i) monitoring a respiratory flow of air of the patient after said ventilator has cycled; (ii) creating a signal indicative of said flow; (iii) removing artefact from said signal; (iv) monitoring said signal for perturbations; and (v) determining that an ineffective effort has occurred when said perturbation is significant.
US08602998B2	Use of relaxin to increase arterial compliance The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
US08602988B2	Recovery determination methods and recovery determination apparatuses Recovery determination methods and recovery determination apparatuses are described. According to one aspect, a recovery determination method includes accessing an input for a recovery marker which corresponds to a characteristic of an individual, wherein the input comprises data pertinent to the individual for the recovery marker while the individual is at rest following a period of exercise by the individual, processing the data of the individual for the recovery marker, and determining recovery information which is indicative of a state of recovery of the individual using the processing.
US08602987B2	Techniques for evaluating stress urinary incontinence (SUI) using involuntary reflex cough test A system and method evaluates a patient for stress urinary incontinence. An involuntary reflex cough event is induced within the patient that activates the nucleus ambiguous and medial motor cell column of the patient and stimulates involuntary cough activated paraspinal muscles in the pelvis of the patient. And elecromyogram (EMG) is obtained from the involuntary cough activated paraspinal muscles and its duration determined. Any urine leakage time that occurs during the involuntary reflex cough event is identified and correlated within a processor together with the urine leakage time and EMG and duration of cough event to determine stress urinary incontinence.
US08602986B2	System and method for detecting signal artifacts A method and system are disclosed that detect signal artifacts in one or more event signals. The system and method may be used with a patient monitoring apparatus that adapts to a patient's condition and distinguishes between clinically significant changes in the patient's state verse clinically insignificant changes.
US08602984B2	Surgical retractor systems and illuminated cannulae This invention includes surgical retractors that comprise an expandable frame that includes at least two base components, a connector, and at least two retractor blades attached to the expandable frame. Also included are surgical retractors that comprise a housing component that includes a cylindrical portion and a contiguous blade portion, assemblies comprising a surgical retractor assembled to at least one obtruator, illuminated surgical cannulas, and methods of using the same during a surgical procedure.
US08602983B2	Access assembly having undercut structure An assembly for accessing a body cavity is provided. The access assembly includes a flexible outer sleeve configured to be received through an opening in tissue. The outer sleeve defines a passageway therethrough and a notch formed about an inner surface thereof. The access assembly further includes a support plate configured for selective reception through the passageway of the outer sleeve and within the notch formed in the inner surface. The support plate defines at least a first opening configured to receive a surgical instrument therethrough.
US08602982B2	Surgical access system and related methods A surgical access system including a tissue distraction assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
US08602980B2	Folding endoscope and method of using the same A folding endoscope with incorporated optical sensors and light sources includes a housing having first and second ends and a longitudinal axis and at least one channel extending between the first and second ends and associated ports at the first and second ends for inserting surgical instruments through the housing into a surgical site. The endoscope includes at least two elongate arms having proximal and distal ends and being pivotally connected at the distal ends thereof to the first end of the housing. A camera and light source are mounted on each of the elongate arms such that when the elongate arms are deployed the cameras have a field of view in a generally forward direction away from the housing. A linkage mechanism is connected to the elongate arms, and an actuator is connected to the linkage mechanism. The linkage mechanism, upon activation by the actuator, is configured to pivotally deploy the at least two elongate arms from a closed position in which the elongate arms are aligned along the longitudinal axis to an open position with the distal ends of the elongate arms radially spaced from the longitudinal axis.
US08602979B2	Electronic endoscope having front-view and side-view image capturing A distal portion of an electronic endoscope is formed with a cutaway portion and a distal end surface. The distal portion is provided with side-viewing and front-viewing capturing optical systems. The side-viewing capturing optical system has a side-viewing objective lens, a prism with a half mirror surface, and a varifocal lens. Light incident on the half-mirror surface from the side-viewing objective lens is reflected to be incident on a CCD through the varifocal lens. Moving the varifocal lens allows the side-viewing capturing optical system to switch from normal observation to magnifying observation and vice versa. In the magnifying observation, a best focus position resides on an extension, of an outer circumferential surface of the distal portion, facing the cutaway portion.
US08602972B2	Image pickup apparatus and endoscope apparatus incorporating the same An image pickup apparatus is provided with a prism unit, two solid image pickup devices, two FPCs electrically connected to the solid image pickup devices and on which an electronic component is mounted, respectively, and two communication cables for supplying power to the electronic components through the FPCs and carrying out signal transmission/receiving with the solid image pickup devices, in which a first communication cable and a second communication cable are arranged adjacently and disposed so that a line connecting a center of the first communication cable to a center of the second communication cable is in a diagonal direction of an incident face of the second solid image pickup device in a plane perpendicular to an optical axis O of an objective lens unit.
US08602970B2	Lifting cap An endoscope procedure instrument provided with: a tube part that is cylindrical in shape and attaches to the front end of the endoscope, the tube part having a slit provided to the side surface thereof extending along the direction of the central axis; and a grasping member that is disposed to the tube part extending along the slit, for holding a biologic tissue with respect to the endoscope.
US08602969B2	Capsule medical apparatus system A capsule medical apparatus system includes a rotating magnetic field generation apparatus that generates a desired rotating magnetic field in three-dimensional directions, a capsule medical apparatus that includes a magnet and a needle for puncture that can be projected and retracted in a rotation direction of the rotating magnetic field and is rotated in the direction of the rotating magnetic field when the rotating magnetic field is applied to the magnet, a step-out operation detecting unit that detects a step-out operation by which the capsule medical apparatus is inversely rotated when a luminal surface is punctured with the needle, and a magnetic-field control instructing unit that controls the rotating magnetic field generation apparatus on the basis of a detection result performed by the step-out operation detecting unit.
US08602961B2	Apparatus and method of stimulating elevation of glutathione levels in a subject An apparatus configured to provide a beneficial biological effect for a subject, and/or a method of treating the subject using the apparatus. The apparatus may be configured to trigger and maintain the elevation of Glutathione levels within the subject. The apparatus may rely on a non-invasive mechanism to elevate Glutathione levels in the subject. The apparatus may not require a traditional power source such as a battery or wall plug in order to be effective in elevating Glutathione levels in the subject. To trigger and maintain the elevation of Glutathione levels within the subject, the apparatus may transmit communication to the body of the subject that results in increased levels of Glutathione within the subject.
US08602957B2	Incremental velocity changing apparatus for transporting printed products in a printing press folder A printing press folder is provided. The printing press folder includes a pair of cutting cylinders cutting a web at a cutting location to form signatures, a pair of transport cylinders positively gripping and transporting the signatures and a pair of acceleration cylinders positively gripping and transporting the signatures. The transport cylinders define a first nip and the first nip and the cutting location are separated by a first distance that is slightly shorter than a length of each of the signatures. The acceleration cylinders define a second nip. The pair of transport cylinders receives and releases signatures at a first velocity and the pair of acceleration cylinders receives the signatures from the pair of transport cylinders and releases the signatures at a second velocity that is greater than the first velocity. The first nip and the second nip are separated by a distance that is slightly shorter than the length of each of the signatures, such that the transport cylinders release each of the signatures as the acceleration cylinders grip the respective signature and the transport and acceleration cylinders maintain positive control over the signatures during transport. A signature transport apparatus and a method for transporting printed products in a printing press folder are also provided.
US08602951B2	Variable resistance fitness chamber for rotational torque One example embodiment includes a resistance chamber for use in an exercise system. The resistance chamber includes a first chamber and a second chamber. The second chamber is configured to attach to the first chamber and rotate relative to the first chamber. The resistance chamber also includes a core rod. The core rod resides within the first chamber and the second chamber and is attached to the interior of the second chamber. The resistance chamber further includes a resistance tube, where at least of a portion the resistance tube is configured to be placed between the interior surface of the first chamber and the core rod.
US08602945B1	Weightlifting laser light guidance tool The laser light weightlifting training appliance and guidance system will apply visible horizontal and vertical line or lines to a wall or chart during weight training exercises. A laser light housing holds the light source and attaches it to a weight or weightlifting bar. The housing is preferably provided with three laser light conveyance windows which may be used by the lifter or his coaches to receive immediate feedback as to the quality of his weight training technique and work out. The laser light housing is affixed to the weight training apparatus in any number of known manners. A built-in bubble-type level ensures the level mounting of the appliance housing onto the weight system. The combination of the laser and a landing position of the manipulated laser's light line or cross-shape on a wall or a chart permits a lifter to guide, improve, or correct his weight training technique.
US08602942B2	Centrifugal de-clutch A mechanical mechanism is used to prevent a rotor of an aircraft from rotating when the rotor is not in use. The mechanical mechanism disengages when the speed of the rotor exceeds a speed threshold and the mechanism reengages when the speed of the rotor is below the speed threshold.
US08602940B2	Driving force transmission device A hybrid driving force transmission device includes an engine (E), a motor-clutch unit (MC), and a transmission unit (T). The motor-clutch unit (MC) is coupled to the engine (E), and includes a multi-plate dry clutch (7) and a slave cylinder (8). The transmission unit (T) is coupled to the motor-clutch unit (MC), and includes a transmission housing (41), a V-belt type continuously variable transmission mechanism (42), and an oil pump (OP). A cylinder housing (81) which comprises a first clutch pressure oil passage (85) communicating with the slave cylinder (8) is provided in the motor-clutch unit (MC). By coupling the motor-clutch unit (MC), a second clutch pressure oil passage (47) is brought into communication with the first clutch pressure oil passage (85) in the cylinder housing (81). An end plate (45) having the second clutch pressure oil passage (47) is provided in the transmission unit (T).
US08602932B2	Chain There is provided a chain comprising guide link rows and non-guide link rows disposed alternately along the length of the chain with each plate of each row overlapping each plate of each of two adjacent rows. For each guide link row, a pair of pins is provided for connecting the guide link rows and non-guide link rows in articulating relationship. The first connecting pin extends into a first hole of each of the guide plates of its guide link row and into and through the second hole of each link plate of an adjacent non-guide link row. The second connecting pin extends into a second hole of each of the guide plates extends into and through a first hole of each link plate of an adjacent non-guide link row. The connecting pins fit tightly into each first hole into which it extends and fits loosely in each second hole into which it extends.
US08602927B2	Game ball and method of manufacturing same A game ball, such as a soccer ball, having a cover comprised of one or more cover panel blanks and one or more reinforcement material blanks, is provided. The cover panel blanks and reinforcement material blanks are heat bonded together so that the free edges and interior panel boundaries of the cover panel blanks are aligned with the reinforcement material blanks.
US08602926B2	Composite arrow vane Disclosed is a composite arrow vane for mounting to a projectile. The composite arrow vane is constructed of a composite material that includes a polymer matrix around structural elements. In some embodiments, the polymer matrix may be a thermoplastic polyurethane. The structural elements compounded into the polymer may be voids, hollow glass beads or just about any structure having a weight per unit volume that is less than the weight per unit volume of the polymer matrix. Advantageously, the composite material allows for reduced dimensions of the composite arrow vane because the increased tensile strength of the material allows for size reductions without significantly compromising vane performance. Similarly, the lighter weight per unit volume of the composite material as compared to a homogeneous polymer allows for increased flight speed of the projectile.
US08602924B2	Baseball or softball bat A baseball or softball bat improved in repulsiveness while maintaining sufficient durability is obtained. The bat is a baseball or softball bat including a hitting portion, a tapered portion and a grip portion, and the hitting portion offers a hitting portion core as a core, an elastic body and an outer shell member. The elastic body is arranged on the outer periphery of the hitting portion core. The outer shell member is arranged on the outer periphery of the elastic body. The outer shell member includes outer shell member portions which are a plurality of portions elastically deformable independently of each other.
US08602921B2	Lightweight portable goal post Low cost, durable, reusable, lightweight, inexpensive, simple, easy to assemble/disassemble, transportable goal posts. Each goal posts may be composed of single piece T reinforcements and a single piece cross bar reinforcement, as well as readily available construction materials, such as PVC pipe. The bodies of the single piece reinforcements are sized so that the pipes forming the upright posts and crossbar have the same length. Assembly, disassembly, and transportation are simplified. The disassembled components can be carried in vans and SUVs. Internal reinforcements allow flexible, low cost materials such as PVC pipe to be used while maintaining a professional, aesthetic appearance.
US08602916B2	Low lift golf ball A golf ball having a plurality of dimples formed on its outer surface, the outer surface of the golf ball being divided into plural areas comprising dimples such that the golf ball is spherically symmetrical as defined by the United States Golf Association (USGA) Symmetry Rules, the plural areas configured such that the golf ball exhibits a lift coefficient (CL) of less than about 0.195 over a range of Reynolds Number (Re) from about 135,000 to about 180,000 and at a spin rate of about 3000 rpm.
US08602913B2	Putter head A putter head includes a head main body having a depressed portion and a face insert disposed within the depressed portion so that the face insert is mounted in a face surface of the head main body. The face insert includes at least one low hardness portion and at least one high hardness portion. The face insert has a boundary face between the at least one low hardness portion and the at least one high hardness portion which is inclined relative to a back-to-forth direction of the putter head. The boundary face may decline toward the rear or may rise toward the rear. The face insert may comprise a plurality of the low hardness portions and a plurality of the high hardness portions so that the low and high hardness portions are arranged vertically in multiple layers. The sectional shapes taken perpendicularly to the back-to-forth direction of the high hardness portion and the low hardness portion may be substantially of a right triangle. The face insert may comprise a surface layer and groove portions on a front face thereof.
US08602908B2	Golf club shaft A shaft of the present invention has a tip reinforcing layer. A prepreg s9 for the tip reinforcing layer has a portion having a larger circumferential direction width Ws toward a tip side. The prepreg s9 for the tip reinforcing layer has a thickness Pt of 0.06 mm or greater and 0.12 mm or less. An edge Ds of the tip reinforcing layer extends in an axial direction of the shaft while circulating in a circumferential direction of the shaft. An average value Ha of the five heights h11 to h15 is equal to or less than 0.03 mm.
US08602907B2	Golf club A golf club comprises a shaft, a club head, and a connection assembly that allows the shaft to be easily disconnected from the club head. In particular embodiments, a sleeve including a top portion, a middle portion connected to the top portion is described. The middle portion includes a thin wall thickness. A bottom portion is connected to the middle portion including a plurality of engaging surfaces. A central longitudinal axis and an offset angle offset from the central longitudinal axis is described. The offset angle allows a maximum loft change of about 0.5 degrees to about 4.0 degrees. The total weight of the sleeve is less than 9 g.
US08602906B2	Bowling pin and method of manufacture A bowling pin including a body having a head, a neck, a ball line portion, and a base all integrally formed of a synthetic material. The body includes a hollow area and a longitudinal axis of the hollow area extends generally perpendicularly to a substantially planar bottom surface of the base. A method of manufacturing a bowling pin includes providing a mold shell having a mold cavity shaped substantially as a bowling pin, disposing a mandrel inside a mold cavity, introducing material into the mold cavity, cooling the material inside the mold cavity, removing the mandrel from the mold cavity, removing the material from the mold cavity, and cooling the material outside the mold cavity.
US08602900B2	Torque fluctuation absorber A torque fluctuation absorber includes a first plate member to which power of rotation is transmitted from a first rotational shaft, a second plate member arranged at a preset distance from the first plate member, a third plate member arranged between the first plate member and the second plate member and configured to transmit power of rotation to a second rotational shaft. The torque fluctuation absorber also includes a fourth plate member arranged at a preset distance from the second plate member, and a resilient member arranged between the second plate member and the fourth plate member and configured to bias the second plate member towards the third plate member. The fourth plate member includes a fulcrum point that supports a mid portion of the resilient member.
US08602898B2	Shaft arrangement for a transmission A shaft arrangement for a transmission comprises a shaft having an axial bore connected to an oil supply system, at least one loose wheel rotatably supported on the shaft via a bearing, and a shift clutch arrangement which connects the loose wheel for rotation with the shaft. The shift clutch arrangement comprises a guide sleeve connected for rotation with the shaft via a tooth engagement. The axial bore supplies oil to the bearing and shift clutch arrangement via a transversal bore in an area of the tooth engagement between the guide sleeve and the shaft. A channel in at least one of an area of a toothing of the guide sleeve and an area of the toothing of the shaft, which, together with the guide sleeve toothing, forms the tooth engagement connects the transversal bore with an area between the guide sleeve and the bearing.
US08602897B2	Extended and editable gamer profile A user profile for an online gaming service is created. The user profile contains user gaming information received from a first location. The user profile is stored in a database, and the user is permitted to access the user profile from a second location.
US08602894B2	Illuminating controller for interfacing with a gaming system A controller for use in interfacing with a computer game. The controller includes a handle having at least one button, and a spherically shaped object connected to only one end of the handle. The spherically shaped object is defined from a translucent plastic material. Further included as part of the controller is an illuminating means defined within the spherically shaped object. A circuit is also provided for interpreting input data from the at least one button and communicating data wirelessly. The circuit is further configured to interface with the illuminating means to trigger illumination of the spherically shaped object to switch from an un-illuminated color to an illuminated color.
US08602893B2	Input for computer device using pattern-based computer vision Images of a least a portion of a structurally encoded pattern formed on a surface from a camera can be analyzed to determine a position of a camera. The structurally encoded pattern can include a plurality of elements. Each element can be encoded with information identifying a location and orientation of the element with respect to the surface. A computer program can identify at least a portion of one or more pattern elements in the image and determine the position of the camera relative to the surface from the information encoded in the one or more pattern elements in the image.
US08602891B2	Image display system and illumination device The present invention is directed to an image display system for displaying an image on a display screen. The image display system includes a light-emitting portion, a lighting portion, a display control portion, and a lighting control portion. The light-emitting portion emits infrared light. The lighting portion sheds visible light. The display control portion performs predetermined information processing based on a detection result for the infrared light, thereby controlling image display on the display screen. The lighting control portion controls lighting by the lighting portion.
US08602889B2	Game program for moving object from one display to another display When a method of operating a player character 40 is displayed on a first LCD 11, a movement of an enemy character 41 displayed on a second LCD 12 temporarily stops and the player character 40 moves from a display screen of the second LCD 12 to a display screen of the first LCD 11. Thus, a player's sight line is guided from the display screen of the second LCD 12 to the display screen of the first LCD 11 along with the movement of the player character 40, thereby allowing the player to confirm; with no oversight, that explanatory information regarding the method of operating the player character 40 is displayed.
US08602885B2	Proximity based game customization Potential player proximity to a gaming machine is sensed, and used to customize the gaming machine. The potential player position may be sensed in different manners including via an ID card carried by the potential player with triangulation sensors, a cell phone, or via biometrics. The identity of the player is also associated with the ID card, and is used to access a database containing information about the potential player or type of player. Based on that stored information, the proximate gaming machine may be customized with a game or various attract modes that are more likely to attract the potential player. In further embodiments, information known to be desired by the potential player, such as sporting results may also be displayed to attract the potential player. In still further embodiments, various profiling techniques may be utilized to identify desired customizations of proximately located gaming machines.
US08602882B2	Jackpot interfaces and services on a gaming machine A disclosed a player tracking unit provides a touch screen display with a touch screen controller integrated into the touch screen sensor assembly. Game service interfaces may be presented on the touch screen display that allow a user to obtain one or more game services. With the touch screen sensor, a user may navigate through the game service interface and supply information required to obtain a game service. Types of interfaces provided with the gaming machine include a jackpot interface for displaying one or more jackpots selected by the player or one or more jackpots that the player is eligible to win.
US08602881B2	Sponsored hybrid games Systems and methods in accordance with embodiments of the invention operate a sponsored hybrid game that includes: a gambling game; an entertainment game; a game world engine constructed to communicate gameplay gambling event occurrences based upon a player's skillful execution of the entertainment game that trigger at least one wager in the gambling game; and a sponsorship module integrated with the game world engine constructed to: receive sponsorship terms involving allocation of gameplay resources during sponsored gameplay of the sponsored hybrid game between at least one player profile and at least one sponsor profile; allocate gameplay resources associated with at least one sponsor profile to at least one player profile based on the sponsorship terms for use in sponsored gameplay; and allocate gameplay resources resulting from a payout of gameplay resources during the sponsored gameplay using the sponsorship terms.
US08602872B2	Method and apparatus for outputting outcomes of a gaming device In accordance with one or more embodiments, a method for outputting an outcome for a game of a gaming device is presented, wherein the method comprises first outputting an apparent outcome for the game and then outputting an actual outcome for the game. In one or more embodiments, a benefit corresponding to the apparent outcome may not be provided to the player playing the gaming device. For example, a hopper may be prevented from dispensing a payout associated with the apparent outcome. In accordance with one or more embodiments, a character (e.g., an animated character) may be displayed as changing the apparent outcome into the actual outcome.
US08602864B1	Method and device for conducting a numbers game with a prize component At least one game matrix is generated. Number indicia are selected and any matches between the selected number indicia and the game matrix are identified. The numbers game component is resolved based on the identified matches. One or more game hands are formed by assigning a prize indicium and/or game indicium to each match. Optionally, game indicia are randomly assigned to game matrix locations lacking a match. In an embodiment based on Bingo, a game hand may be formed based on the pattern of matches. The game hand component of a game is resolved based on a comparison of the game hand to a standard, such as a pay table, dealer hand, and/or other game hands of other players. A prize component is resolved based on whether a predetermined collection of prize indicia is obtained.
US08602863B2	Method and apparatus for determining a game series comprising a plurality of individually selectable wagering games A wagering method is provided that allows players or gaming establishments to specify conditions which when satisfied, reconfigure the gaming device to change game play from a first game to a second game. The condition may depend upon the value of a parameter—generally related to game play—to determine if the condition is valid and triggers the reconfiguration. The second game may be selected from a game on the same gaming device, from a game on a different gaming device, or a game played by a specific player.
US08602862B2	Gaming machine displaying special symbol having randomly selected functions Disclosed herein is a game played on a gaming device that displays a randomly selected array of symbols, where the symbols across one or more pay lines are evaluated by circuitry to determine an award to be granted. One of the possible symbols is a special symbol that offers various special functions. The special symbol switches between two or more states, where each state provides a different function. The switching is stopped randomly or by the player, and the resulting function is carried out. In another embodiment, the special symbol allows symbols to be moved in the array or provides other functions.
US08602861B2	Method and apparatus for a wagering game including an option to quickly progress a multi-state game to completion A method, apparatus, and computer readable storage to implement a progression type game, such as a simulated sport or other game. The game has multiple intermediate game states. The player has the option to bet during the intermediate parts of the game, or accelerate the game to completion. The acceleration option, when exercised, displays the game in a fast version so that the player can quickly see the outcome of the game and receive any earned winnings.
US08602860B2	Multi-play poker game with pool hand A method for playing a multiple-play poker game includes the step of displaying a pool hand comprising a plurality of face up cards. The pool hand is not played, subject to wager, or subject to poker hand rankings. The pool hand is provided solely as a means for designation of none, one or more of the cards of the pool hand as held cards. Preferably, at the time of display of the pool hand and designation of held cards, playing hands are not displayed, keeping the player focused on the selection process. The method continues with reproducing the held cards in a plurality of playing hands, completing the plurality of playing hands with new face up cards, if any, and determining a ranking of each of the completed playing hands.
US08602858B2	Game device, computer program therefor, and recording medium therefor A game device causes a display device to display an image in which plural marks correlated with step panels to be stepped on by a player move to reach a base line, and the game device, when a step panel is stepped on, classifies the degree of accuracy of this operation as one of plural classes based on a time at which a mark corresponding to this step panel reaches the base line, a time at which this step panel was stepped on, and plural thresholds. The game device counts the number of accurate operations, to cause the display device to display the number in a color corresponding to the lowest accurate operation class corresponding to the counted accurate operations.
US08602856B2	Threshing bars and combine harvester thresher formed therewith A combine harvester threshing drum threshing bar includes a rigid, integral, unitary threshing fixture having a leading edge and an opposed trailing end, an upstream face and an opposed downstream face formed with an oblique crop deflecting surface, a threshing side and an opposed threshing drum emplacement side. The threshing side includes a trailing threshing face formed toward the trailing end of the threshing fixture, and an inclined leading threshing face extending from the trailing threshing face to the leading edge, and which cooperates with the threshing drum emplacement side and the upstream and downstream faces of the threshing fixture at the leading edge to form a wedge in the threshing fixture. Crop threshing grooves are formed in the trailing threshing face of the top threshing side of the threshing fixture, which extend from the trailing end to the leading threshing face of the threshing fixture.
US08602854B1	Apparatus and methods for active scent control in hunting blinds A scent control system for use in a hunting blind enclosure includes an exhaust conduit adapted to exhaust air from the hunting blind enclosure and an air driver in fluid communication with the exhaust conduit. The air driver is operable to intake air from within the enclosure and exhaust air through the exhaust conduit and is further adapted to provide a negative air pressure within the enclosure relative to an air pressure outside of the enclosure. A filter disposed between an outlet of the air driver and the exhaust conduit filters human scent from air being exhausted from the enclosure.
US08602846B2	Polishing pad and a method for manufacturing the same A polishing pad of excellent durability and adhesion between the polishing layer and the base material layer includes a polishing layer arranged on a base material layer, wherein the polishing layer includes a thermosetting polyurethane foam having roughly spherical interconnected cells having an average cell diameter of 20 to 300 μm. The polyurethane foam includes an isocyanate component and an active hydrogen-containing compound as starting material components, and the active hydrogen-containing compound includes 30 to 85% by weight of a high-molecular-weight polyol having 2 to 4 functional groups and a hydroxyl value of 20 to 100 mg KOH/g.
US08602845B2	Strengthening by machining A machining method comprises selecting a finished surface dimension and a material property for a working surface, defining a working temperature range based on the selected material property, and defining a machining power based on the working temperature range. The machining power depends on a removal rate and a specific heat of the working surface. The working surface is machined at the removal rate to achieve the finished surface dimension, and the machine power is controlled to maintain the working surface within the working temperature range. The working surface is heated or cooled from the working temperature range to a transition temperature range, such that the selected material property is preserved in the working surface.
US08602844B2	Method and apparatus for working on workpieces with a water jet that contains abrasive and emerges under high pressure from a nozzle In a method for producing a water jet (45) that contains abrasive and emerges under high pressure from a nozzle (44), uninterrupted operation with, at the same time, greater working performance and lower costs is made possible in that, in a first step, an abrasive suspension (34) containing abrasive and water is provided at normal pressure, in a second step the provided abrasive suspension (34) is brought to a working pressure that is greatly above normal pressure, and in a third step a water jet (45) containing abrasive is produced, with a nozzle (44), from the abrasive suspension (34) that is under the working pressure.
US08602841B2	Form tap and method of making such A form tap includes a shank having a shank length and a thread portion that extends along at least a portion of the shank length. The thread portion includes a finishing portion and a chamfer portion. Each of the finishing portion and the chamfer portion include a plurality of threads and each thread has a crest and a root. The plurality of threads of both the finishing portion and the chamfer portion are spaced apart at a constant pitch, such that a crest-to-crest distance between adjacent threads remains constant along the entire thread portion.
US08602830B2	Terminal component and portable electronic device A terminal component that is inexpensive and has a high degree of freedom of mounting and a portable electronic device using the terminal component are provided. The terminal component 15 includes a metal plate 41 having a contact surface 15a to contact a power supply terminal 105 of a charging stand 101, wherein at least two portions of an end part of the metal plate 41 are bent, and a resin member 43 that is held by the bent portions. A part to be mounted 41c on a sub-substrate 31 is formed at the bent portions of the metal plate 41.
US08602822B2	Connector devices having increased weld strength and methods of manufacture Devices and methods of manufacture for improved connector plugs are provided herein. In one aspect, an exemplary connector plug comprises a shield shell having a proximal stepped-down portion and a boot member that fittingly receives the stepped-down proximal portion so that an outer surface of the distal shield shell and the boot member is about flush with a minimal or negligible space therebetween. In some embodiments, the shield shell comprises a separate front shield shell and a reduced profile rear shield shell welded together so as to provide the advantageous reduced profile and improved aesthetic appearance, while maintaining the structural integrity of the connector. In many embodiments, weld strength of the shield shells is improved by providing line-to-line contact between shield shells by using deflectable tabs and/or utilizing thermal expansion properties of one or both shield shells.
US08602821B2	Electrical connector having an electronic device A connector (10) has a capacitor (20) connected to a ground-side terminal (32) formed by press-working a metal base material in the form of a flat plate and is accommodated in a housing (50) made of synthetic resin. A connecting head (38) is provided on the ground-side terminal (32) and is thinner than the base material. The connecting head (38) is connected to a ground-side electrode (21B) provided on the capacitor (20) by soldering. A resiliently deformable neck (39) on the ground-side terminal (32) is narrower than the connecting head (38) and extends from the connecting head (38). A molded portion (53) is provided in the housing (50) to integrally cover the ground-side electrode (21B) of the capacitor (20) and the connecting head (38) of the ground-side terminal (32).
US08602816B2	Connector device for electronic modules in automation systems A connector device for electronic modules including a housing, i.e., in automation systems, having a termination panel with plug-in locations for wiring, wherein the termination panel is pivotally guidable onto the electronic module, and wherein the connector device is pivotable to a pre-wiring position outside the housing to provide access to the plug-in locations of the termination panel.
US08602804B2	Power plug locking device A power plug locking device includes a lock unit that restricts movement of an operation arm arranged on a power plug. The lock unit includes a first member, which is moved between a lock position and an unlock position, and a second member, of which movement is restricted in accordance with the movement of the first member. The second member restricts the movement of the operation arm in cooperation with the first member that is moved to the lock position. The first member includes a first contact surface. The second member includes a second contact surface that is able to contact the first member that is moved to the lock position. At least one of the first contact surface and the second contact surface includes a stepped shape.
US08602802B2	Easy assembling one click bulb socket An easily assembling light bulb socket as disclosed secures a light bulb in a single clicking action. The disclosed socket comprises an electrically conductive sleeve configured to clasp a threaded end of the light bulb. The sleeve comprises a bump configured to slide into a thread recess and click-secure the bulb in the sleeve. A first disk received into the socket is riveted to the sleeve and to a metallic ribbon. The sleeve rivet makes a connection with a first wire and the ribbon rivet makes a connection with a second wire. The socket additionally comprises a second disk defining two holes aligned with the rivet holes in the first disk to receive a respective wire there through. The second disk holes include elliptical recesses configured to channel and secure the first and second wires between the disks when the second disk is axially rotated adjacent the first disk.
US08602800B2	Electrical connector having alignment mechanism An electrical connector assembly may include a connector body having a conductor receiving end and first and second connector ends formed substantially perpendicularly to an axial direction of the conductor receiving end. The connector body includes a first axial bore that communicates with each of a second axial bore and a third axial bore in the first and second connector ends, respectively. The electrical connector assembly may include a conductor spade assembly received in the first axial bore, wherein the conductor spade assembly includes a spade portion extending between the second axial bore and the third axial bore. A removeable contact may be received within the second axial bore to conductively engage the spade portion of the conductor spade assembly.
US08602795B2	Electrical connector An electrical connector includes a first connector, and a second connector detachably coupled to the first connector. The first connector has a first magnetic body and at least one first conductive body. The second connector has a second magnetic body and at least one second conductive body. The first magnetic body is capable of magnetically attracting the second magnetic body to form a sealed enclosure to receive the at least one first conductive body and the at least one second conductive body. The at least one first conductive body electrically connects to the at least one second conductive body when the first magnetic body is magnetically bound to the second magnetic body.
US08602793B1	Real time learning and self improvement educational system and method The real time learning system and method provides a self learning environment to learn language or subjects faster and easier using textual content obtained in real time. The system is a computer-aided and management educational system that includes a real-time content processing module, a learning management Module, a content management database, an exercise generator module with Dictionaries, Picture Media, Music Libraries, Life Management and a User block. The system transforms any Real Time textual information into learning content and implements user learning exercises. Learning exercises are automatically created as multiple choice tests, filling blanks, quizzes, puzzles, crosswords, etc. from this learning content in real-time, based on a teacher or student online request for information. Linguistic text processing, keyword extraction and semantic procedures allow extraction of text information with a different data set to generate more intellectual exercises as comprehension tests, writing and grammar exercises. Different learning technologies are used to generate exercise implementation as visual mnemonics for remembering (Syntality1), interactive templates, games, multi-sensor activities. A Life Management module includes a Personal Action Success Strategy (PASS) System that contains Time Management, Motivation and Goal Setting Systems.
US08602791B2	Generation of test stimuli in visual media Test stimuli for visual media may be generated by incorporation of one or more element images selected from a library into a presentation area. The test stimuli may be displayed or presented to one or more subjects and metrics indicating the attentiveness of the subjects to various locations in the composite image may be measured. These metrics may be analyzed with placement parameters for incorporation of the element images into the composite image to determine subject reactions to various aspects of the test stimuli.
US08602785B2	Smart magazine for simulated weapon A smart magazine adapted to be releasably engaged with a simulated weapon is provided, the magazine comprising a housing, a valving mechanism disposed within the housing and a data module including an electronic storage medium for storing information concerning an amount of simulated ammunition “shots” present in the magazine, and a connection member operably connected to the data module and adapted to be operably connected to a control module in the weapon to transmit and receive signals in response to the firing of the weapon to adjust the number of “shots” stored in the storage medium. The magazine utilizes a compressed gas cartridge that releases gas to produce an audible “pop” when the weapon is fired and to reset the “shot” count for the magazine when the canister is replaced.
US08602779B2	Endodontic plugger An endodontic plugger comprises a plugging surface which contacts filler material that has been inserted into a prepared root canal. The plugging surface comprises a plurality of moveable plates which move independently of each other. The movable plates enable the plugger surface to automatically and substantially instantaneously adjust in size and/or shape in response to the cross-sectional size and/or shape of a root canal as the plugger surface passes along the root canal.
US08602777B2	Method and device for causing tooth movement A device for increasing movement of a tooth in a jaw includes a handle, an elongate member extending from the handle, a screw tip at a distal end of the elongate member, and a sleeve. The screw tip is configured to drill into cortical bone of the jaw to increase movement of the tooth. The sleeve is configured to move along the elongate member to vary the length of exposed screw tip.
US08602773B2	Dental impression tray for use in obtaining an impression of a dental structure A dental impression tray, a kit, and method of using the same are provided for taking an impression of at least a portion of a dental structure of a patient. The tray can include a tray portion, fiduciary markers, and can also have a holding section with two opposing sides and fasteners disposed thereon. The kit can include the tray and a handle portion. The handle can be removably secured to the holding section of the tray. In some embodiments, the handle can include a pair of handle portions. In other embodiments, a part of the handle can be aligned with a facial feature of a patient from whom a dental impression is to be obtained.
US08602766B2	Rotary forming devices and methods for using such devices Rotary forming devices and methods of using the rotary forming devices for producing products such as filled and unfilled “pillow” shaped products. In an embodiment, the invention provides a device comprising a housing comprising a die plate defining a plurality of outlets. The housing defines an inlet. A race plate is attached to the die plate. The race plate circumscribes the outlets of the die plate. A forming wheel is rotatably attached to the die plate. A motor assembly is attached to the forming wheel. The motor assembly is constructed and arranged to rotate the forming wheel in a hypocycloid motion.
US08602763B2	Apparatus for heating preforms The invention relates to a device for heating of preforms formed of plastic with infrared radiation, whereby the preform is struck by cooling air at its neck finish and on its body. Furthermore, the infrared radiators are struck by cooling air at their ends. The invention relates to a heating device in which the three cooling air streams may be controlled or regulated independently from each other.
US08602760B2	Vane compressor A vane compressor according to the present invention, including a cylinder which is approximately cylindrical and whose both ends located in an axial direction are open, a cylinder head and a frame which close both the ends of the cylinder, a rotor shaft which includes a rotor part being cylindrical and rotating in the cylinder and a shaft part transmitting torque to the rotor part, and a vane which is installed in the rotor part and whose tip portion has the R-shape facing outward, performs the compression operation in the state where the normal to the R-shape of the tip portion of the vane and the normal to the inner surface of the cylinder are always approximately coincident with each other.
US08602759B2	Screw-type vacuum pump having overpressure openings A screw vacuum pump, in particular for compression against atmospheric pressure, comprises a pump housing defining a suction chamber. Two meshing screw rotors are arranged in the suction chamber. Further, an overpressure outlet provided, which comprises an overpressure opening in a side wall of the suction chamber. Further, an overpressure valve is arranged in the overpressure outlet. The width (b) of the overpressure opening in the longitudinal direction of the screw rotors is smaller than or equal to a tooth width (B) of the screw rotors.
US08602758B2	Indexed positive displacement rotary motion device An indexing system for a rotor assembly where the indexing system can regulate the rotational location of drive rotors that are configured to rotate about a shaft in one form.
US08602756B2	Scroll type compressor having an elastic member to suppress noise and reduce variations Provided is a scroll type compressor which reduces variations in the pressing load of a rotating scroll on a fixed scroll, reduces the impact at the start of the compressor and suppresses noises, and can provide excellent durability. A peripheral elastic body 51 and a bottom-portion elastic body 52, which is brought into a compressed condition in the axis line direction of the main shaft 31, are interposed between a stopper pin 41 on the rotating scroll side and a concave portion 42 on the main shaft 31 side, whereby working errors of each part are compensated and the rotating scroll is constantly brought into close contact with the fixed scroll to maintain the sealing of the compression chamber.
US08602755B2	Rotary compressor with improved suction portion location A rotary compressor is provided. The rotary compressor may include a plurality of cylinders each having a suction port formed such that an intersection of a center line of the suction port and a center line of a vane slot is positioned at a predetermined interval closer to the vane slot than to an intersection between a center of an inner diameter of the cylinder and the center line of the vane slot. A proximal end of the suction port may be formed in the vicinity of the vane slot so as to advance a compression start angle of a compression space and reduce a dead volume between the vane slot and the suction port, thus improving compressor performance.
US08602752B2	Electric compressor An electric compressor is disclosed in which gas in a motor housing of a rotating electric machine is drawn into a compression chamber and then discharged by the rotating electric machine. The rotating electric machine includes a stator, teeth, coils of different phases, and phase-to-phase insulation sheets provided between coils of different phases. An inlet port is provided in the motor housing. The inlet port draws gas from the outside of the motor housing. An inflow direction of the gas flowing through the inlet port intersects a coil end of one of the coils. A part of the phase-to-phase insulation sheet faces the inlet port and covers an intersection surface of the coil end that intersects the inflow direction.
US08602750B2	Liquid supply device A drive characteristic and durability of a liquid supply device having a flexible pump member such as a bellows are improved. A drive pump in the liquid supply device has a bellows as the pump member that is elastically deformed axially by a drive rod. A drive pump chamber and a communication chamber are formed by the bellows and the housing, and the communication chamber and the drive pump chamber are partitioned by the orifice member. At a drive operation time of the drive rod, the through hole is blocked by the valve member, and a liquid flows in between the communication chamber and the drive pump chamber via a communication gap formed between the orifice member and an inner circumferential face of the housing.
US08602749B2	Variable displacement vane pump A variable displacement vane pump includes, but is not limited to inlet and outlet ports in a pump body, a drive shaft rotatably mounted in the pump body, a rotor driven by the drive shaft and radially extending vanes slidably disposed in the rotor. A slide is pivotally disposed on a pivot and has a central axis eccentric to the axis of the rotor. Chambers are defined by the rotor, the vanes and the slide that are successively connected to the inlet and outlet ports. A resilient member is pivotally engaged with the slide and acts on the slide to urge the slide in one direction.
US08602743B2	Method of operating a safety vacuum release system Embodiments of the invention provide a method of operating a safety vacuum release system (SVRS) with a controller for a pump including a motor. The method can include measuring an actual power consumption of the motor necessary to pump water and overcome losses. The method can include triggering the SVRS when a dynamic suction blockage is identified in order to shut down the pump substantially immediately. The SVRS can also be triggered when a dead head condition is identified based on the actual power consumption.
US08602739B2	Wind turbine rotor blade and pitch regulated wind turbine A wind turbine rotor blade with an airfoil profile having an upwind side, a downwind side is provided. A stall inducing device is located at the upwind side of the airfoil profile.
US08602736B2	Stow abort mechanism for a ram air turbine A disclosed ram air turbine assembly includes a movable support structure that is prevented from moving to a stowed position by a stow abort mechanism that prevents movement to the stowed position when the turbine is not in a desired orientation.
US08602731B2	Microprocessor system for controlling rotor pitch A rotor blade is used in combination with a submersible electrical generator for generating electricity to be put into the grid, where the pitch of the rotor blade is controlled by a microprocessor. The microprocessor controls a radio frequency transmitter which emits signals to a receiver which controls a hydraulic value. The hydraulic valve controls a push-pull arrangement which through a right angle gear and pitch adjustment axial adjust the rotor pitch according to pre-programmed conditions stored in the microprocessor.
US08602730B2	Multi stage radial compressor A multistage radial compressor (1) with at least two compressor stages for compressing a fluid has a compressor housing (16) in which a flow channel (2) is formed for the fluid to be compressed; an impeller (4) with a plurality of impeller vanes (5) which are arranged in the flow channel (2) and are rotatable with the impeller (4) around a driveshaft (A), and a 3D return blading (8) with a plurality of return vanes (9) which are fixed with respect to rotation relative to the compressor housing (16). The flow channel (2) has a curved deflecting channel (7) which is arranged in front of the return vanes (9) in the flow direction. A vane base (11) and/or, axially downstream thereof, a vane head (12) of the return vanes (9) of the 3D return blading (8) have/has a curvature, and/or the return vanes (9) have a first vane angle distribution (17) at the vane base (11) and a second vane angle distribution (18) differing from this at the vane head (12).
US08602729B2	Steam turbine stage A stage of a steam turbine, having a rotor extending along a longitudinal axis, has a fixed stage and a movable stage arranged successively along a flow channel for feeding steam in a direction substantially parallel to the longitudinal axis; the fixed stage has an inner ring coaxial with the longitudinal axis, and a number of stator blades arranged radially about the inner ring; each stator blade is fixed to an annular top portion of the inner ring, which has a top surface facing the flow channel and crosswise to the longitudinal axis; and the movable stage has a number of rotor blades arranged radially about the rotor and fixed to the rotor.
US08602728B2	Centrifugal compressor diffuser vanelet A system, in certain embodiments, includes a centrifugal compressor diffuser including a flow path having a first surface and a second surface defining opposite axial sides of the flow path. The centrifugal compressor diffuser also includes multiple vanes extending from the first surface to the second surface of the flow path. A first profile of each vane varies along an axial direction. The centrifugal compressor diffuser further includes multiple vanelets extending from the first surface toward the second surface in the axial direction. A first axial extent of each vanelet is less than a second axial extent of the flow path. In addition, a second profile of each vanelet varies along the axial direction and/or the vanelets form a non-periodic pattern around a circumference of the flow path.
US08602725B2	Ceiling fan A configuration including outer-rotation motor portion (4) including stator (2) with a center through which fixed axis (1) passes, and rotor (3) pivotally supported capable of rotating around stator (2); a plurality of blade plates (5) radially arranged on rotor (3); support base (6) having fixed axis (1) in a center thereof and located in a lower part of stator (2); angle changing unit (7) provided on support base (6); and a plurality of stationary blade plates (9) being detachably placed on stationary blade holders provided on angle changing unit (7). With the configuration in which an elevation/depression angle of stationary blade plates (9) is adjustable by at least one stationary blade driving motor (10) that drives angle changing unit (7), a structure is simplified.
US08602723B2	Heat dissipating blower A heat dissipating blower includes a main body and a cover. The main body includes a shell and a fan. An outlet and a first gap are defined in the shell. A connecting portion is set at one end of the first gap away from the outlet. Two sliding grooves are formed on inner surfaces of a first wall and a second wall and a plurality of locating holes is set on the two sliding grooves. The cover includes two parallel side plates and a middle plate. A plurality of positioning pins is set on outer surfaces of the two side plates. Some of the positioning pins are located in corresponding ones of the locating holes to change an area of the outlet.
US08602719B2	Vertical axis wind turbine A vertical axis wind turbine having a plurality of upright airfoils pivotally engaged. A continuous adjustment of the angle of attack of the airfoils to oncoming wind is provided by rotation of a control plate connected to the vanes which are mounted upon a rotating drive plate. A vane can be employed to rotate the control plate to affect the continuous adjustment of the airfoils.
US08602718B2	Transverse-axis turbine with twisted foils A turbine, suitable for use as a water or wind turbine, for generating rotary motion from fluid flow wherein the axis of rotation of the turbine is transverse to the direction of flow. The turbine has two foils, which may meet at the axis of rotation, and the turbine is helical and tapered. The turbine has a quasi-conical base. The non-mount end of the turbine is preferably tilted downstream with the turbine axis of rotation in the range of about 5° to 15° from perpendicular to the flow direction.
US08602716B2	Semiconductor manufacturing process modules A method is provided where the method includes configuring a plurality of robots so that a wafer can be handed off between neighboring robots, and disposing a plurality of sensors so that a robotic arm-relative position of a wafer that is transported by a robot is determined from sensor outputs by moving the wafer through a retract, rotate, and extend path.
US08602712B2	Demountable vehicle body system This invention relates to a demountable vehicle body system, in which a variety of different body types can be mounted and demounted from a vehicle chassis or trailer to enable a single vehicle chassis or trailer to be utilized for a variety of different purposes. In particular, the present invention relates to a demountable vehicle body system for motor vehicles and trailers which provides for a convenient and cost effective use of a variety of vehicle body types. Advantageously, the present invention provides a demountable vehicle body system that is capable of safely mounting or demounting a wide variety of vehicle body types, including fully-loaded heavy bodies, in a smooth and efficient manner. The vehicle body system described herein can be mounted or demounted in a matter of minutes by a single operator.

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