最新美国发明专利第2013-11-19期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08587102B2	Vertical system integration The Vertical System Integration (VSI) invention herein is a method for integration of disparate electronic, optical and MEMS technologies into a single integrated circuit die or component and wherein the individual device layers used in the VSI fabrication processes are preferably previously fabricated components intended for generic multiple application use and not necessarily limited in its use to a specific application. The VSI method of integration lowers the cost difference between lower volume custom electronic products and high volume generic use electronic products by eliminating or reducing circuit design, layout, tooling and fabrication costs.
US08587100B2	Lead frame and semiconductor package using the same A semiconductor package includes a lead frame, a first chip, a second chip, a plurality of bonding wires and a mold compound. The lead frame includes a pad portion at a center of the frame and a plurality of lead portions. The pad portion and the plurality of lead portions collectively define a receiving portion. The first chip is securely received in the receiving portion. The second chip is mechanically attached to the first chip. The plurality of bonding wires electrically connect the second chip to the plurality of lead portions. The mold compound encapsulates the lead frame, the first chip, the second chip and the plurality of bonding wires to form the semiconductor package.
US08587092B2	Semiconductor device and manufacturing method of the same A protective insulation film covering a surface of a compound semiconductor region is formed to have a two-layer structure of a first insulation film and a second insulation film which have different properties. The first insulation film is a non-stoichiometric silicon nitride film while the second insulation film is a silicon nitride film in an almost stoichiometric state.
US08587087B2	Semiconductor device and manufacturing method of the same In order to improve characteristics of an IGBT, particularly, to reduce steady loss, turn-off time and turn-off loss, a thickness of a surface semiconductor layer is set to about 20 nm to 100 nm in an IGBT including: a base layer; a buried insulating film provided with an opening part; the surface semiconductor layer connected to the base layer below the opening part; a p type channel forming layer formed in the surface semiconductor layer; an n+ type source layer; a p+ type emitter layer; a gate electrode formed over the surface semiconductor layer via a gate insulating film; an n+ type buffer layer; and a p type collector layer.
US08587083B2	Microbolometer semiconductor material A sensor for detecting intensity of radiation such as of infrared radiation includes an ROIC substrate (9) and a resistance element (1) arranged at a distance of the surface of the ROIC substrate. The resistance element comprises one more semiconducting layers such as a silicon semiconducting layer and a semiconducting layer of a silicon-germanium alloy forming a heterojunction. The semiconducting layer or layers can be doped with one or more impurity dopants, the doping level or levels selected so that the layer retains the basic crystallographic properties of the respective material such as those of monosilicon or a monocrystalline silicon-germanium alloy. The impurity dopants are selected from the elements in groups IE, IV, and V, in particular among boron, aluminium, indium, arsenic, phosphorous, antimony, germanium, carbon and tin. The doping can be abrupt so that there is an interior layer inside said semiconducting layer or layers having a significantly higher doping level.
US08587078B2	Integrated circuit and fabricating method thereof A fabricating method of integrated circuit is provided. During the fabricating process of an interconnecting structure of the integrated circuit, a micro electromechanical system (MENS) diaphragm is formed between two adjacent dielectric layers of the interconnecting structure. The method of forming the MENS diaphragm includes the following steps. Firstly, a plurality of first openings is formed within any dielectric layer to expose corresponding conductive materials of the interconnecting structure. Secondly, a bottom insulating layer is formed on the dielectric layer and filling into the first openings. Third, portions of the bottom insulating layer located in the first openings are removed to form at least a first trench for exposing the corresponding conductive materials. Then, a first electrode layer and a top insulating layer are sequentially formed on the bottom insulating layer, and the first electrode layer filled into the first trench and is electrically connected to the conductive materials.
US08587074B2	Device having a gate stack A device includes a drain, a source, and a gate stack. The gate stack has a gate dielectric layer, a gate conductive layer immediately on top of the gate dielectric layer, and first gate and a second gate layer that are immediately on top of the gate conductive layer. The first gate layer has a first resistance higher than a second resistance of the second gate layer. The second gate layer is conductive, is electrically coupled with the gate conductive layer, and has a contact terminal configured to serve as a gate contact terminal for the device. Fabrication methods of the gate stack are also disclosed.
US08587073B2	High voltage resistor Provided is a semiconductor device. The semiconductor device includes a resistor and a voltage protection device. The resistor has a spiral shape. The resistor has a first portion and a second portion. The voltage protection device includes a first doped region that is electrically coupled to the first portion of the resistor. The voltage protection device includes a second doped region that is electrically coupled to the second portion of the resistor. The first and second doped regions have opposite doping polarities.
US08587071B2	Electrostatic discharge (ESD) guard ring protective structure An ESD protection circuit includes a MOS transistor of a first type, a MOS transistor of a second type, an I/O pad, and first, second, and third guard rings of the first, second, and first types, respectively. The MOS transistor of the first type has a source coupled to a first node having a first voltage, and a drain coupled to a second node. The MOS transistor of the second type has a drain coupled to the second node, and a source coupled to a third node having a second voltage lower than the first voltage. The I/O pad is coupled to the second node. The first, second, and third guard rings are positioned around the MOS transistor of the second type.
US08587070B2	Method of forming a semiconductor structure A method of forming a semiconductor structure comprises forming a first layer of silicon and then forming a second, silicon germanium, layer adjacent the silicon layer. A thin third layer of silicon is then formed adjacent the second layer. A gate structure is then formed upon the third layer of silicon using convention Complementary Metal Oxide Semiconductor processes. Trenches are then formed into the second layer and the structure is then exposed to a thermal gaseous chemical etchant, for example heated hydrochloric acid. The etchant removes the silicon germanium, thereby forming a Silicon-On-Nothing structure. Thereafter, conventional CMOS processing techniques are applied to complete the structure as a Metal Oxide Semiconductor Field Effect Transistor, including the formation of spacer walls from silicon nitride, the silicon nitride also filling a cavity formed beneath the third layer of silicon by removal of the silicon germanium.
US08587067B2	Graphene devices and silicon field effect transistors in 3D hybrid integrated circuits A three dimensional integrated circuit includes a silicon substrate, a first source region disposed on the substrate, a first drain region disposed on the substrate, a first gate stack portion disposed on the substrate, a first dielectric layer disposed on the first source region, the first drain region, the first gate stack portion, and the substrate, a second dielectric layer formed on the first dielectric layer, a second source region disposed on the second dielectric layer, a second drain region disposed on the second dielectric layer, and a second gate stack portion disposed on the second dielectric layer, the second gate stack portion including a graphene layer.
US08587066B2	Structure and method having asymmetrical junction or reverse halo profile for semiconductor on insulator (SOI) metal oxide semiconductor field effect transistor (MOSFET) A device and method is provided that in one embodiment provides a first semiconductor device including a first gate structure on a first channel region, in which a first source region and a first drain region are present on opposing sides of the first channel region, in which a metal nitride spacer is present on only one side of the first channel region. The device further includes a second semiconductor device including a second gate structure on a second channel region, in which a second source region and a second drain region are present on opposing sides of the second channel region. Interconnects may be present providing electrical communication between the first semiconductor device and the second semiconductor device, in which at least one of the first semiconductor device and the second semiconductor device is inverted. A structure having a reverse halo dopant profile is also provided.
US08587063B2	Hybrid double box back gate silicon-on-insulator wafers with enhanced mobility channels A semiconductor wafer structure for integrated circuit devices includes a bulk substrate; a lower insulating layer formed on the bulk substrate; an electrically conductive back gate layer formed on the lower insulating layer; an upper insulating layer formed on the back gate layer; and a hybrid semiconductor-on-insulator layer formed on the upper insulating layer, the hybrid semiconductor-on-insulator layer comprising a first portion having a first crystal orientation and a second portion having a second crystal orientation.
US08587061B2	Power MOSFET device with self-aligned integrated Schottky diode A power MOSFET device and manufacturing method thereof, includes the steps of selectively depositing a first conductive material in the middle region at the bottom of a contact trench and contacting with light-doped N-type epitaxial layer to form a Schottky junction and depositing a second conductive material at the side wall and bottom corner of the contact trench and contacting with P-type heavy-doped body region to form an ohmic junction. The first and second conductive materials can respectively optimize the performance of the ohmic contact and the Schottky contact without compromise. Meanwhile, the corner of the contact trench is surrounded by P-type heavy-doped region thereby effectively reducing the leakage currents accumulated at the corner of the contact trench.
US08587058B2	Lateral diffused metal-oxide-semiconductor device The present invention provides a lateral diffused metal-oxide-semiconductor device including a first doped region, a second doped region, a third doped region, a gate structure, and a contact metal. The first doped region and the third doped region have a first conductive type, and the second doped region has a second conductive type. The second doped region, which has a racetrack-shaped layout, is disposed in the first doped region, and has a long axis. The third doped region is disposed in the second doped region. The gate structure is disposed on the first doped region and the second doped region at a side of the third doped region. The contact metal is disposed on the first doped region at a side of the second doped region extending out along the long axis, and is in contact with the first doped region.
US08587055B2	Integrated circuit using a superjunction semiconductor device In an embodiment, an apparatus includes a source region, a gate region and a drain region supported by a substrate, and a drift region including a plurality of vertically extending n-wells and p-wells to couple the gate region and the drain region of a transistor, wherein the plurality of n-wells and p-wells are formed in alternating longitudinal rows to form a superjunction drift region longitudinally extending between the gate region and the drain region of the transistor.
US08587054B2	Trench MOSFET with resurf stepped oxide and diffused drift region A trench MOSFET with split gates and diffused drift region for on-resistance reduction is disclosed. Each of the split gates is symmetrically disposed in the middle of the source electrode and adjacent trench sidewall of a deep trench. The inventive structure can save a mask for definition of the location of the split gate electrodes. Furthermore, the fabrication method can be implemented more reliably with lower cost.
US08587050B2	Semiconductor memory In one embodiment, there is provided a semiconductor memory that includes: a semiconductor substrate having a channel region; a first tunnel insulating film on the channel region; a first fine particle layer on the first tunnel insulating film, the first fine particle layer including first conductive fine particles; a second tunnel insulating film on the first fine particle layer; a second fine particle layer on the second tunnel insulating film, the second fine particle layer including second conductive fine particles; a third tunnel insulating film on the second fine particle layer; a third fine particle layer on the third tunnel insulating film, the third fine particle layer including third conductive fine particles. A mean particle diameter of the second conductive fine particles is larger than that of the first conductive fine particles and that of the third conductive fine particles.
US08587044B2	Complementary logic device using spin injection A complementary logic device includes: an insulating layer formed on a substrate; a source electrode formed of a ferromagnetic body on the insulating layer; a gate insulating film; a gate electrode formed on the gate insulating film and controlling a magnetization direction of the source electrode; a channel layer formed on each of a first side surface and a second side surface of the source electrode and transmitting spin-polarized electrons from the source electrode; a first drain electrode formed on the first side surface of the source electrode; and a second drain electrode formed on the second side surface of the source electrode, wherein a magnetization direction of the first drain electrode and a magnetization direction of the second drain electrode are antiparallel to each other. Therefore, not only characteristics of low power and high speed but also characteristics of non-volatility and multiple switching by spin may be obtained.
US08587042B2	Magnetoresistive random access memory device An aspect of the present disclosure, there is provided a magnetoresistive random access memory device, including, an active area formed on a semiconductor substrate in a first direction, a magnetoresistive effect element formed on the active area and storing data by a change in resistance value, a gate electrode of a cell transistor formed on each side of the magnetoresistive effect element on the active area in a second direction, a bit line contact formed on the active area and arranged alternately with the magnetoresistive effect element, a first bit line connected to the magnetoresistive effect, and a second bit line connected to the bit line contact.
US08587037B1	Test structure to monitor the in-situ channel temperature of field effect transistors A field effect transistor (FET) having a source, a drain and a gate includes a first connection electrically connected to the gate near a first end of the gate, a second connection electrically connected to the gate near the first end of the gate, a third connection electrically connected to the gate near a second end of the gate, and a fourth connection electrically connected to the gate near the second end of the gate. By performing gate resistance measurements at different ambient temperatures, a thermal coefficient of gate resistance can be derived and then used to monitor the gate temperature, which is representative of the channel temperature.
US08587036B2	Non-volatile memory and fabricating method thereof A non-volatile memory is formed on a substrate. The non-volatile memory includes an isolation structure, a floating gate, and a gate dielectric layer. The isolation structure is disposed in the substrate to define an active area. The floating gate is disposed on the substrate and crosses over the active area. The gate dielectric layer is disposed between the floating gate and the substrate. The floating gate includes a first region and a second region. An energy band of the second region is lower than an energy band of the first region, so that charges stored in the floating gate are away from an overlap region of the floating gate and the gate dielectric layer.
US08587033B1	Monolithically integrated HEMT and current protection device A transistor device includes a high electron mobility field effect transistor (HEMT) and a protection device. The HEMT has a source, a drain and a gate. The HEMT switches on and conducts current from the source to the drain when a voltage applied to the gate exceeds a threshold voltage of the HEMT. The protection device is monolithically integrated with the HEMT so that the protection device shares the source and the drain with the HEMT and further includes a gate electrically connected to the source. The protection device conducts current from the drain to the source when the HEMT is switched off and a reverse voltage between the source and the drain exceeds a threshold voltage of the protection device. The protection device has a lower threshold voltage than the difference of the threshold voltage of the HEMT and a gate voltage used to turn off the HEMT.
US08587031B2	Dual-gate normally-off nitride transistors A dual-gate normally-off nitride transistor that includes a first gate structure formed between a source electrode and a drain electrode for controlling a normally-off channel region of the dual-gate normally-off nitride transistor. A second gate structure is formed between the first gate structure and the drain electrode for modulating a normally-on channel region underneath the second gate structure. The magnitude of the threshold voltage of the second gate structure is smaller than the drain breakdown of the first gate structure for proper operation of the dual-gate normally-off nitride transistor.
US08587026B2	Semiconductor device and manufacturing method thereof This invention relates to a semiconductor device and a manufacturing method therefor for reducing stacking faults caused by high content of Ge in an embedded SiGe structure. The semiconductor device comprises a Si substrate with a recess formed therein. A SiGe seed layer is formed on sidewalls of the recess, and a first SiGe layer having a Ge content gradually increased from bottom to top is formed on the recess bottom. A second SiGe layer having a constant content of Ge is formed on the first SiGe layer. The thickness of the first SiGe layer is less than the depth of the recess. The Ge content in the SiGe seed layer is less than the Ge content in the second SiGe layer, and the Ge content at the upper surface of the first SiGe layer is less than or equal to the Ge content in the second SiGe layer.
US08587024B2	Vertical junction field effect transistors and bipolar junction transistors Methods of making semiconductor devices such as vertical junction field effect transistors (VJFETs) or bipolar junction transistors (BJTs) are described. The methods do not require ion implantation. The VJFET device has an epitaxially regrown n-type channel layer and an epitaxially regrown p-type gate layer as well as an epitaxially grown buried gate layer. Devices made by the methods are also described.
US08587023B2	Guard rings with local coupling capacitance A guard ring system is disclosed for protecting an integrated circuit comprising. It has a first guard ring area formed by a well in the substrate, a capacitor area formed within the first guard ring area which further includes two well contacts formed into the well and biased by a first supply voltage, and a dielectric layer placed between the two contacts on the well with its first side in contact with the well. A second supply voltage complementary to the first supply voltage is applied to a second side of the dielectric layer so that a voltage difference across the dielectric layer provides a local capacitance embedded therein.
US08587022B2	Nitride semiconductor light-emitting element and process for production thereof A nitride-based semiconductor light-emitting device 31 includes: an n-type GaN substrate 1 which has an m-plane principal surface; a current diffusing layer 7 provided on the n-type GaN substrate 1; an n-type nitride semiconductor layer 2 provided on the current diffusing layer 7; an active layer 3 provided on the n-type nitride semiconductor layer 2; a p-type nitride semiconductor layer 4 provided on the active layer 3; a p-electrode 5 which is in contact with the p-type nitride semiconductor layer 4; and an n-electrode 6 which is in contact with the n-type GaN substrate 1 or the n-type nitride semiconductor layer 2. The donor impurity concentration of the n-type nitride semiconductor layer 2 is not more than 5×1018 cm−3, and the donor impurity concentration of the current diffusing layer 7 is ten or more times the donor impurity concentration of the n-type nitride semiconductor layer 2.
US08587021B2	Mounting structure for solid state light sources A mounting structure for solid-state light sources, for example of the LED type, comprises a support board; a submount mounted on said support board and having at least one solid-state light radiation source mounted thereon; a drive board carrying drive circuitry for the light radiation source, the aforementioned drive board being mounted on the support board and extending peripherally with respect to the aforementioned submount; electrical interface connections between the submount and the drive board for connecting the light radiation source to the drive circuitry; and mechanical and thermal interface connections between the submount and the support board.
US08587020B2	LED lamps A high power LED lamp has a GaN chip placed over an AlGaInP chip. A reflector is placed between the two chips. Each of the chips has trenches diverting light for output. The chip pair can be arranged to produce white light having a spectral distribution in the red to blue region that is close to that of daylight. Also, the chip pair can be used to provide an RGB lamp or a red-amber-green traffic lamp. The active regions of both chips can be less than 50 microns away from a heat sink.
US08587018B2	LED structure having embedded zener diode A light emitting diode (LED) structure comprises a first dopant region, a dielectric layer on top of the first dopant region, a bond pad layer on top of a first portion the dielectric layer, and an LED layer having a first LED region and a second LED region. The bond pad layer is electrically connected to the first dopant region. The first LED region is electrically connected to the bond pad layer.
US08587011B2	Light-emitting device, light-emitting module, and lamp A light-emitting device which emits light omnidirectionally is provided. A light-emitting device according to the present invention includes: a package which is translucent; an LED provided in a recess in the package; and a sealing member for sealing the LED and packaging the recess; and the recess includes a bottom surface on which the LED is mounted and a side surface surrounding a bottom surface, and light emitted by the LED is transmitted inside the package through the bottom surface and the side surface of the recess and is emitted to outside of the package from the back surface and the side surface of the package.
US08587009B2	Light emitting chip package A light emitting chip package includes a substrate, an insulation layer, a patterned electric conductive layer, a light emitting chip, an encapsulation, a plurality of thermal conductors and electrical conductors. The insulation layer is formed on a top surface of the substrate. The patterned electric conductive layer partially covers the insulation layer. The light emitting chip is arranged on the electric conductive layer. The encapsulation covers the light emitting chip and the electric conductive layer. The plurality of thermal conductors is formed at a bottom surface side of the substrate. The plurality of electrical conductors penetrates the insulation layer and connects the conductive layer with the thermal conductor. The plurality of electrical conductors is isolated from each other.
US08587008B2	Light-emitting device A light-emitting device includes a substrate, a plurality of light-emitting elements mounted on one surface of the substrate, a first glass film provided to one surface of the substrate and having a plurality of apertures that form a light-reflecting frame surrounding the perimeter of each the light-emitting elements, and a second glass film provided to the other surface of the substrate. A coefficient of thermal expansion of the second glass film is greater than that of the substrate when a coefficient of thermal expansion of the first glass film is greater than that of the substrate, and a coefficient of thermal expansion of the second glass film is less than that of the substrate when a coefficient of thermal expansion of the first glass film is less than that of the substrate.
US08587006B2	Organic light-emitting display An organic light-emitting display apparatus including a thin-film transistor (TFT) is disclosed. In one embodiment, the organic light-emitting display apparatus includes a thin-film transistor (TFT) and an organic light-emitting device electrically connected to the TFT. The apparatus further includes a light blocking portion formed directly above at least a portion of the TFT and configured to prevent light, emitted from the organic light-emitting device, from entering the portion of the TFT.
US08587005B2	Nitride semiconductor light emitting device array A nitride semiconductor light emitting device array, which includes a dielectric layer formed on a first conductivity lower nitride semiconductor layer, having a plurality of windows. Each of a plurality of hexagonal pyramid light emission structures is grown from a surface of the first conductivity lower nitride semiconductor layer exposed through each of the windows and onto a peripheral area of the window of the dielectric layer. Each of the hexagonal pyramid light emission structures includes a first conductivity upper nitride semiconductor layer, an active layer and a second conductivity nitride semiconductor layer formed in their order. The windows are disposed in such a triangular arrangement that side surfaces of the adjacent hexagonal pyramid light emission structures face each other. Also, a distance between bases of the adjacent hexagonal pyramid light emission structures is less than 0.3 times an interval between centers of the windows of the adjacent hexagonal pyramid light emission structures.
US08587004B2	Semiconductor light emitting device, its manufacturing method, semiconductor device and its manufacturing method A semiconductor light emitting device made of nitride III-V compound semiconductors including an active layer made of a first nitride III-V compound semiconductor containing In and Ga, such as InGaN; an intermediate layer made of a second nitride III-V compound semiconductor containing In and Ga and different from the first nitride III-V compound semiconductor, such as InGaN; and a cap layer made of a third nitride III-V compound semiconductor containing Al and Ga, such as p-type AlGaN, which are deposited in sequential contact.
US08587001B2	Light-emitting diode light module free of jumper wires An LED light module free of jumper wires has a substrate and multiple LED chips. The substrate has a positive side circuit, a negative side circuit, multiple first chip connection portions and multiple second connection portions. The first and second chip connection portions are respectively connected to the positive and negative side circuits, and are juxtaposedly and alternately arranged on the substrate so that a width between each first chip connection portion and a corresponding second chip connection portion is smaller than a width of each LED chip. Each LED chip can be directly mounted on corresponding first and second chip connection portions to electrically connect to the positive and negative side circuits. Accordingly, jumper wires for connecting the LED chips and the positive and negative side circuits can be removed to avoid broken jumper wires occurring when the LED light module is shipped or assembled.
US08586999B1	Apparatus pertaining to a core of wide band-gap material having a graphene shell A core consisting essentially of a wide band-gap material has a shell consisting essentially of graphene conformally disposed about at least a substantial portion thereof. By one approach the core has at least one bisectional dimension that does not exceed 100 nanometers. By one approach a connection between a pathway that connects the shell to the core comprises a photovoltaic junction.
US08586994B2	Semiconductor device A semiconductor device includes: an electron-transit layer made of a semiconductor, the electron-transit layer having a first band gap; an electron-supply layer disposed on the electron-transit layer, the electron-supply layer being made of a semiconductor having a second band gap that is wider than the first band gap; a barrier-forming layer disposed on the electron-supply layer, the barrier-forming layer being made of a semiconductor having a third band gap that is narrower than the second band gap; an upper-channel layer disposed on the barrier-forming layer, the upper-channel layer being made of a semiconductor doped with an impurity; a side-surface of the barrier-forming layer and the upper-channel layer formed by partly removing the barrier-forming layer and the upper-channel layer; an insulating-film disposed on the side-surface; a gate-electrode disposed on the insulating-film; a source-electrode connected to the upper-channel layer; and a drain-electrode connected to the electron-supply layer or the electron-transit layer.
US08586984B2	Organic light-emitting display device and method of manufacturing the same An organic light-emitting display device includes an active layer of a thin film transistor arranged on a substrate, a first insulating layer and a gate electrode arranged on the active layer, the gate electrode including a first transparent conductive layer and a first metal layer, a second insulating layer arranged on the gate electrode and including a plurality of contact holes that expose a source region and a drain region of the active layer, a reflective layer and a second transparent conductive layer arranged within the contact holes, a source electrode and a drain electrode arranged on the second transparent conductive layer and on the second insulating layer, the source electrode and the drain electrode each including a second metal layer, a pixel electrode arranged on the first insulating layer, the pixel electrode including the first transparent conductive layer, the reflective layer, and the second transparent conductive layer, an intermediate layer arranged on the pixel electrode and including an organic emission layer and an opposite electrode facing the pixel electrode, wherein the intermediate layer is arranged between the pixel electrode and the opposite electrode.
US08586982B2	Semiconductor test chip device to mimic field thermal mini-cycles to assess reliability A semiconductor test device including a plurality of conductive layers, each of the layers comprising integrated circuit devices, a plurality of insulating layers between the conductive layers, a plurality of heat generating structures positioned between the insulating layers and the conductive layers, each of the heat generating structures being sized and positioned to only heat a predetermined limited area of the plurality of layers, a plurality of thermal monitors positioned within each of the plurality of layers, a control unit operatively connected to the heat generating structures and the thermal monitors, the control unit individually cycling the heat generating structures on and off for multiple heat cycles, such that different areas of the layers are treated to different heat cycles.
US08586981B2	Silicon-on-insulator (“SOI”) transistor test structure for measuring body-effect According to one exemplary embodiment, a silicon-on-insulator (SOI) transistor test structure includes a gate situated over a semiconductor body and a doped halo under the gate. The SOI transistor test structure further includes at least two semiconductor body contacts situated on opposing sides of the doped halo, where one or more of the at least two semiconductor body contacts forms a direct electrical contact with the doped halo, thereby increasing current flow to the doped halo to facilitate measuring body-effect in the SOI transistor test structure.
US08586978B2	Non-volatile memory device including diode-storage node and cross-point memory array including the non-volatile memory device Provided are a non-volatile memory device and a cross-point memory array including the same which have a diode characteristic enabling the non-volatile memory device and the cross-point memory array including the same to operate in a simple structure, without requiring a switching device separately formed so as to embody a high density non-volatile memory device. The non-volatile memory device includes a first electrode; a diode-storage node formed on the first electrode; and a second electrode formed on the diode-storage node.
US08586975B2	Photoelectric conversion element, method for manufacturing photoelectric conversion element, and electronic apparatus A photoelectric conversion element includes a first electrode, a second electrode, and a photoelectric conversion element provided between the first electrode and the second electrode. The photoelectric conversion element includes a polymer. The polymer includes at least one light absorber which absorbs light and generates at least one kind of carrier. An end part of the polymer combines with a surface, which faces the second electrode, of the first electrode.
US08586971B2	Polymeric material, method of forming the polymeric material, and method of forming a thin film using the polymeric material A polymeric material includes a pendant polycyclic aromatic compound precursor.
US08586970B2	Organic light emitting display device having polarizable particles in sealant and method of manufacturing the same There is provided an organic light emitting display device including a first substrate; an organic light emitting unit formed on the first substrate; a second substrate disposed on the organic light emitting unit; and an adhesive unit for adhering the first substrate and the second substrate to each other, wherein the adhesive unit includes a sealant, and particles that are arranged in the sealant so as to block penetration of external impurities. There is further provided a method of manufacturing the organic light emitting display device.
US08586962B2	Cross point memory arrays, methods of manufacturing the same, masters for imprint processes, and methods of manufacturing masters A cross point memory array includes a structure in which holes are formed in an insulating layer and a storage node is formed in each of the holes. The storage node may include a memory resistor and a switching structure. The master for an imprint process used to form the cross-point memory array includes various pattern shapes, and the method of manufacturing the master uses various etching methods.
US08586961B2	Resistive changing device A device that incorporates teachings of the present disclosure may include, for example, a memory array having a first array of nanotubes, a second array of nanotubes, and a resistive change material located between the first and second array of nanotubes. Other embodiments are disclosed.
US08586958B2	Switching element and manufacturing method thereof A switching element includes: a first electrode supplying metal ions; a second electrode less ionizable than the first electrode; and an ion conducting layer arranged between the first electrode and the second electrode and containing a metal oxide that can conduct the metal ions. The ion conducting layer includes two or more layers of different types, and one of the ion conducting layers that is closest to the first electrode has a larger diffusion coefficient for the metal ions than that of the other ion conducting layer(s).
US08586957B2	Three-terminal cascade switch for controlling static power consumption in integrated circuits A three-terminal switching device for use in integrated circuit devices, including a phase change material (PCM) disposed in contact between a first terminal and a second terminal; a heating device disposed in direct electrical contact between said second terminal and a third terminal, said heating device positioned proximate said PCM, and configured to switch the conductivity of a transformable portion of said PCM between a lower resistance crystalline state and a higher resistance amorphous state; and an insulating layer configured to electrically isolate said heater from said PCM material, and said heater from said first terminal.
US08586953B2	Extreme ultra violet light source device An extreme ultra violet light source device of a laser produced plasma type, in which charged particles such as ions emitted from plasma can be efficiently ejected. The extreme ultra violet light source device includes: a target nozzle that supplies a target material; a laser oscillator that applies a laser beam to the target material supplied from the target nozzle to generate plasma; collector optics that collects extreme ultra violet light radiated from the plasma; and a magnetic field forming unit that forms an asymmetric magnetic field in a position where the laser beam is applied to the target material.
US08586950B2	Method and system for feature function aware priority printing A method and system for photomask pattern generation is provided, and more specifically, a method and system for feature function aware priority printing is provided. The method of printing a photolithographic mask includes fracturing mask design data into write shapes that are multiples of a spot size and passing fractured mask design data to a write tool. Additionally, the method includes writing one or more non-critical shapes according to one or more time-saving rules.
US08586947B1	Compensator for multiple surface imaging A system and method for imaging biological samples on multiple surfaces of a support structure are disclosed. The support structure may be a flow cell through which a reagent fluid is allowed to flow and interact with the biological samples. Excitation radiation from at least one radiation source may be used to excite the biological samples on multiple surfaces. In this manner, fluorescent emission radiation may be generated from the biological samples and subsequently captured and detected by detection optics and at least one detector. The detected fluorescent emission radiation may then be used to generate image data. This imaging of multiple surfaces may be accomplished either sequentially or simultaneously. In addition, the techniques of the present invention may be used with any type of imaging system. For instance, both epifluorescent and total internal reflection methods may benefit from the techniques of the present invention.
US08586945B2	Fluorescence light scanning microscope having a birefringent chromatic beam shaping device A fluorescence light scanning microscope (2) comprises a light source providing excitation light (8) for exciting a fluorophore in a sample to be imaged for spontaneous emission of fluorescence light, and suppression light (7) for suppressing spontaneous emission of fluorescence light by the fluorophore on a common optical axis (4), the suppression wavelength differing from the excitation wavelength; an objective (19) focusing both the excitation (8) and the suppression (7) light to a focus point; a detector (21) detecting fluorescence light (11) spontaneously emitted by the fluorophore; and a chromatic beam shaping device (1) arranged on the common optical axis (4), and including a birefringent chromatic optical element (3) adapted to shape a polarization distribution of the suppression light (7) such as to produce an intensity zero at the focus point, and to leave the excitation light such as to produce a maximum at the focus point.
US08586943B2	Petroleum oil analysis using liquid nitrogen cold stage—laser ablation—ICP mass spectrometry A novel application of a cold-stage coupled to a laser ablation-ICP-MS system is disclosed herein. The novel system of the present invention offers significant advantages over other systems employed for cooling samples prior to LA-ICP-MS analysis. The system discloses herein has multiple applications, including detection of one or more metal contaminants in an oil sample.
US08586940B2	X-ray active pixel sensor (APS) readout circuit and readout method An APS readout circuit includes a pixel sensing unit, an integrating unit, and a voltage offset unit. The pixel sensing unit senses an X-ray irradiation amount to obtain a current signal in varying. The current signal is obtained by subtracting a sensing current in varying from a base current. The integrating unit is coupled with the pixel sensing unit to receive the current signal and convert the current signal into a voltage signal. The integrating unit includes a short circuit switch with a switch-on state for resetting the integrating unit and a switch-off state for directly outputting the current signal. The voltage offset unit is connected to an output terminal of the integrating unit and generates an offset voltage. In a sampling period, a base voltage of the voltage signal output from the pixel sensing unit is substantially removed by the offset voltage. An amplified sensing voltage is then obtained.
US08586939B2	Multiple source associated particle imaging for simultaneous capture of multiple projections Disclosed herein are representative embodiments of methods, apparatus, and systems for performing neutron radiography. For example, in one exemplary method, an object is interrogated with a plurality of neutrons. The plurality of neutrons includes a first portion of neutrons generated from a first neutron source and a second portion of neutrons generated from a second neutron source. Further, at least some of the first portion and the second portion are generated during a same time period. In the exemplary method, one or more neutrons from the first portion and one or more neutrons from the second portion are detected, and an image of the object is generated based at least in part on the detected neutrons from the first portion and the detected neutrons from the second portion.
US08586937B2	Systems and methods for providing a shared charge in pixelated image detectors Systems and methods for providing a shared charge in pixelated image detectors are provided. One method includes providing a plurality of pixels for a pixelated solid state photon detector in a configuration such that a charge distribution is detected by at least two pixels and obtaining charge information from the at least two pixels. The method further includes determining a position of an interaction of the charge distribution with the plurality of pixels based on the obtained charge information.
US08586933B2	Radiation detector having a split laminate optical coupling A radiation-sensitive detector (120) includes a scintillator array (124) coupled with a photosensor array (140) via an adhesive laminate (144). The photosensor (140) has a plurality of dixels (136). The adhesive laminate (144) includes a material free region that extends through the adhesive laminate (144) from the scintillator array (124) to the photosensor array (140) and that is located between a pair of adjacent dixels (136).
US08586932B2	System and method for radioactive emission measurement A method of radioactive-emission-measurement. The method comprises providing a camera for the detection of single emissions, which defines proximal and distal ends. The camera is configured for enabling a reconstruction of a volumetric image having a line spread function of less than 7 mm Full Width Half Maximum (FWHM) when given a substantially line source of radioactive emission, with an activity of 5 mCi, within a region-of-interest volume, at a distance of at least 100 mm from said distal end, with air being substantially the only operating medium. The method further comprises detecting at least 1 of every 5000 photons, emitted from at least one radioactive-emission source, located within a certain region-of-interest volume, using the camera, and reconstructing a volumetric radioactive-emission image from the detected photons.
US08586920B2	Charged particle beam apparatus It has been difficult to obtain pattern contrast required for inspecting a specific layer of a circuit pattern in a charged particle beam apparatus which inspects, by using a charged particle beam, the position and type of a defect on a wafer having a circuit pattern which is in semiconductor manufacturing process. At the time of inspecting the position and type of a defect on a wafer having a circuit pattern which is in semiconductor manufacturing process by using a charged particle beam emitted from a charged particle source (11), the wafer arranged on a holder (20) is irradiated with light in wavelength ranges different from each other from a light irradiation system (9), and at the same time, the wafer is irradiated with a charged particle beam. Thus, contrast of an image is improved and inspection is performed with high sensitivity.
US08586919B1	Low-voltage transmission electron microscopy Embodiments of the invention relate to electron microscopy. Example embodiments relate to an apparatus including a first electron beam source, a second electron beam source, and a receiving unit. The first electron beam source is configured to provide a first low-voltage electron beam to a surface of a sample. The second electron beam source is configured to provide a second low-voltage electron beam to pass through the sample. The receiving unit is configured to analyze the first low-voltage electron beam, or the second low-voltage electron beam, or both the first and the second electron beam to obtain information about the sample.
US08586916B2	Adhering matter inspection equipment and method for inspecting adhering matter A technology for collecting a granular substance adhering to a baggage with high rate without touching the substance and inspecting whether a dangerous or specific sample material is adhered to the baggage. A method for simplifying or automating such an inspection is also provided. An adhering matter inspection equipment (1) is characterized in that the equipment comprises a collecting section (5) for collecting a sample material peeled off from an inspection object (25) whereupon the sample material is adhered by blowing compression gas through a capturing filter (52), and an inspecting section (2) for analyzing the sample material captured by the capturing filter (52), and further characterized in that the inspection equipment comprises a section (3) for delivering a baggage to the inspecting section (2), and a carrying section (4) for carrying the capturing filter (52) from the capturing section (5) to the inspecting section (2).
US08586915B2	Gas sampling device and gas analyzer employing the same A gas sampling device has a high-vacuum tight chamber formed within its casing, which communicates with an ambient outside through an inlet hole for the gas flow to be ionized and the ambient downstream the ionization chamber with an outlet hole for the ionized gas. A high-vacuum tight membrane separates the inlet hole from the ambient outside the chamber. The membrane has at least one nanohole formed therethrough with a diameter in the order of nanometers.
US08586914B2	Collision cell A method of operating a gas-filled collision cell in a mass spectrometer is provided. The collision cell has a longitudinal axis. Ions are caused to enter the collision cell. A trapping field is generated within the collision cell so as to trap the ions within a trapping volume of the collision cell, the trapping volume being defined by the trapping field and extending along the longitudinal axis. Trapped ions are processed in the collision cell and a DC potential gradient is provided, using an electrode arrangement, resulting in a non-zero electric field at all points along the axial length of the trapping volume so as to cause processed ions to exit the collision cell. The electric field along the axial length of the trapping volume has a standard deviation that is no greater than its mean value.
US08586913B2	Fluidic density measurements based on beta particles detection Devices, methods, and related systems are described for measuring a property of a fluid, including density, in a subterranean environment. A device includes a pressure housing having one or more windows formed in the pressure housing and a flow device arranged in the pressure housing for the fluid to flow through the flow device. Further, a radiation source is mounted within the pressure housing approximate a first source window configured to generate particles into the fluid. The device includes a detector supported by the pressure housing and positioned approximate a first detector window of the one or more windows. The first detector window is located between the detector and the flow device. The detector can be a solid state beta particle detector with a wide band gap, such as the diamond detector, and the radiation source can be a beta particle source, such as a strontium 90 source.
US08586908B2	Time-delay integration through reduction of delay between subsequent capture operations of a light-detection device Disclosed are a system, a method and an apparatus of reduction of delay between subsequent capture operations of a light-detection device. In one embodiment, a light-detection circuit includes an avalanche photodiode implemented in a deep submicron CMOS technology. In addition, the light-detection circuit includes a passive quench control circuit to create an avalanche current that generates a high voltage at an output of a second inverter gate of the circuit. The light-detection circuit further includes an active quench control circuit to reduce a dead time of the circuit. The light-detection circuit also includes a reset circuit to create a low voltage at an output of the second inverter gate and to create an active reset through a PMOS transistor of the light-detection circuit.
US08586898B2	Method and apparatus for dual applicator microwave design The invention described herein pertains generally to a more efficient and cost-effective method and apparatus for: (1) coupling of microwave energy from a microwave generator or plurality of microwave generators into an integral set of applicators; (2) extraction and separation of organic compounds from a mixture of organic and inorganic compounds; and (3) recovery and conversion of the organic compounds to gaseous and liquid fuels. The apparatus described in this invention result in improved microwave absorption within the mixture flowing through the applicators by increasing residence time within the applicators, resulting in a higher temperature within the material. The higher temperature lowers the viscosity of the solution, but also provides a limited reduction of the combination of complex chain and aromatic organic compounds to allow recovery of syngas and fuel oil.
US08586897B2	Microwave applicator A microwave applicator has a coaxial electrical input (4) and a waveguide (1) filled with dielectric (2), an inner conductor (7) of the coaxial input extending longitudinally within one end of the waveguide to launch microwaves in the TM01 mode to travel to the distal end face (8) of the waveguide so that microwaves are transmitted when the distal end face is contacted by the biological tissue to be treated.
US08586896B2	Non-contact rail heater An assembly that is adapted to position a track heater in spaced relation proximate to a surface of a track rail of a railroad. The assembly includes at least one heating element, and a hood or housing that is operable to at least partially surround the heating element while positioning the heating element near to track rail. The hood positions the heating element relative to the rail section such that a gap exists between the heating element and the rail section. As the heating element does not contact the rail, the heating element cannot form an electrical by-pass for signals passing through the rail section.
US08586892B2	Plasma cutter with disconnectable torch and work assemblies Systems and methods relating to securing a torch assembly and a work lead assembly to a plasma cutting power supply are provided. The present disclosure relates to a system and method that allows the torch assembly and the work lead assembly to be readily replaced by the user since the power supply unit need not be opened or disassembled for removal. The present disclosure provides methods and systems for removably securing both the torch assembly and the work lead assembly to the plasma cutting power supply. In one embodiment, the torch assembly and the work lead assembly may be communicatively coupled to the plasma cutting power supply unit via a single cable and a single connector. The connection between the first connector and the first port may be of the quick disconnectable type. The connection between the second connector and the second port may be of the twist lock type, such as a dinse style connector.
US08586888B2	Flotation device safety light switch A safety device for attachment to a flotation device is disclosed comprising a light source, a housing, an actuator mounted within the housing and slideable between a first position wherein the light source is not illuminated and a second position wherein the light source is illuminated. The actuator further comprises a raised boss engageable from outside of the housing, a lanyard at least a portion of which is outside of the housing and a water activated switch wherein when the device is submerged in water, the water activated switch completes an electrical circuit illuminating said light source. The lanyard is releasably connected to an end of the actuator using a separable interconnection assembly. When the lanyard is pulled, the actuator moves from the first position to the second position and on reaching the second position the separable interconnection assembly separates thereby disengaging the lanyard from the actuator. An electrical circuit is completed illuminating the light source and the actuator may be reversed from the second position back into the first position using the raised boss thereby extinguishing the light source.
US08586887B2	Membrane circuit board and luminous keyboard using same A membrane circuit board and a luminous keyboard with such a membrane circuit board are provided. The membrane circuit board includes an upper wiring board and a lower wiring board. The upper wiring board has a first film layer and a first circuit pattern formed on a bottom surface of the first film layer. The lower wiring board has a second film layer, a second circuit pattern and a light reflective element arranged between the second film layer and the second circuit pattern. The first circuit pattern has a plurality of upper contact. The second circuit pattern has a plurality of lower contacts corresponding to respective upper contacts. The upper contacts and the corresponding lower contacts are collectively defined as a plurality of membrane switches. Moreover, a refractive index of the light reflective element is lower than a refractive index of the second film layer.
US08586886B2	Switch mechanism for a power cutter A switch mechanism includes a support structure and an electric switch having an activator moveable between a first position where the electric switch is ON and a second position where the electric switch is OFF. A cam is connected to a first actuator, moveably mounted on the support structure, so that movement of the first actuator results in movement of the cam. A bar is connected to a second actuator, moveably mounted on the support structure, so that movement of the second actuator results in movement of the bar. The cam engages the activator so that movement of the cam by movement of the first actuator results in the activator moving between its two positions. The bar engages the activator so that movement of the bar by movement of the second actuator results in the activator moving between its two positions.
US08586885B2	Force-feedback multidirectional input device A force-feedback multidirectional input device includes a slider slidably supported by a support base and an operation knob joined to the slider. In a sliding operation, the slider operates in conjunction with actuating members included in a force-feedback unit. Therefore, a sense of force based on the sliding is fed back to the operation knob. Furthermore, the slider is elastically urged by coil springs toward an inner bottom surface of a housing space defined in the support base. In a depressing operation, the operation knob presses the support base downward against the urging force of coil springs. Therefore, a vertically movable member joined to the support base is moved downward along guide portions (convex rails and concave grooves). Thus, a push switch provided on a pedestal (circuit board) is pressed and activated by the vertically movable member.
US08586881B1	Connector assembly suited for wet locations A compression ring includes an outer surface opposing an inner surface, with teeth extending radially inwardly from the inner surface. First and second circumferential ends are complementarily interfittable, and are separated by a circumferential gap, allowing the compression ring to be compressable when being installed in a connector assembly. First and second axial ends of the compression ring are chamfered to facilitate compression. The teeth extend circumferentially from the first and second circumferential ends and are complementary to conduit threading. Each tooth includes first and second sides, with the first side perpendicular to the inner surface to resist pullout of a conduit from the connector assembly. The teeth terminate in sharp points for better gripping of unthreaded conduits. A compressed compression ring accommodates threaded conduits by complementarily mating with threading, and unthreaded conduits by biting into their outer surfaces. Internal and external sealing gaskets provide seals from moisture.
US08586880B2	Lead sheath A lead sheath, including an upper jaw, and a lower jaw, the upper jaw and the lower jaw are buckled with each other. A wire outlet hole is formed at the outside of the connection between the upper jaw and the lower jaw. A wire inlet hole is formed at the inside of the connection between the upper jaw and the lower jaw. A cavity is formed between the wire outlet hole and the wire inlet hole. A protruding wire pressing rib is disposed on one of the upper jaw or the lower jaw, and the wire pressing rib extends into the cavity.
US08586879B2	Cable kink protection unit and method for producing same A cable kink protection unit, in particular a cable kink protection unit of a portable tool, includes at least one basic body unit. The cable kink protection unit has at least one electric device housing unit integrally connected to the basic body unit.
US08586877B1	Cam lock mechanism for securing a conduit cover to a conduit body A cam lock mechanism for securing a conduit cover to a conduit body includes a fastener extending from a cam lock. The fastener includes a fastener shaft situated between a fastener head and the cam lock. The fastener may include a flare portion, allowing the fastener to be secured to the cam lock by inserting the flare portion into a cam lock opening and deforming the flare portion. The cam lock may include an at least partially helical cam lock outer portion extending radially outwardly farther than the fastener shaft. When the cam lock mechanism is used to secure a conduit cover to a conduit body, the conduit cover is brought closer to the conduit body as the cam lock mechanism is rotated. A cam lock stopper, such as an upward bend, may be provided in the cam lock to resist overturning of the cam lock mechanism.
US08586874B2	Conductive sheet, method for using conductive sheet, and capacitive touch panel A conductive Sheet, a method for using conductive sheet, and a capacitive touch panel are provided. A first conductive sheet contains two or more conductive first large lattices and a first connection for electrically connecting the adjacent first large lattices on a first transparent substrate. The first large lattices each contain a combination of two or more small lattices, the first connection contains one or more medium lattices (a first medium lattice to a fourth medium lattice), and the pitch of the medium lattices is n times larger than that of the small lattices (in which n is a real number larger than 1).
US08586871B2	Interconnect schemes, and materials and methods for producing the same An interconnect scheme includes a conductive ink forming a plurality of conductive regions, and a dielectric ink occupying spaces between the conductive regions. The conductive ink and the dielectric ink have substantially identical optical, acoustic, and x-ray absorption properties, thereby making the interconnect scheme tamper-resistant and/or difficult to identify and reverse-engineer using conventional detection methods.
US08586870B2	Microelectronic component support with reinforced structure A microelectronic support assembly has a support member formed from plateable resin, such as liquid crystalline polymer and the support member is configured with a laser to define holes in the support member. These holes and other areas of the support member are plated and the plating forms a plurality of hollow metal columns that provide reinforcement to the support member so that it can resist wire bonding pressures.
US08586862B2	Method of manufacturing photovoltaic cells, photovoltaic cells produced thereby and uses thereof Novel methods of producing photovoltaic cells are provided herein, as well as photovoltaic cells produced thereby, and uses thereof. In some embodiments, a method as described herein comprises doping a substrate so as to form a p+ layer on one side and an n+ layer on an another side, removing at least a portion of the n+ layer, and then forming a second n+ layer, such that a concentration of the n-dopant in the second n+ layer is variable throughout a surface of the substrate.
US08586858B2	Passively cooled, high concentration photovoltaic solar cell package The solar cell modular unit has a minimal number of components which are easily manufactured and have a relatively economical cost. It has a laminar substrate having an electrically conductive layer on its top surface with a printed electrical circuit. The middle layer is heat conductive and not electrically conductive. The bottom layer is thermally conductive. A solar cell is centrally mounted on the printed circuit board. A base assembly covers the solar cell and has a vertical tunnel extending from its top surface to the solar cell. A sun shield has an aperture in its top panel that aligns with the tunnel. The sun shield snap-locks onto the base assembly top. A secondary optical element telescopically mates with the aperture in the sun shield and the base assembly tunnel. A primary light ray refractive member is positioned at a predetermined spaced location above the SOE.
US08586857B2	Combined diode, lead assembly incorporating an expansion joint A combined diode, lead assembly incorporating two expansion joints. The combined diode, lead assembly incorporating two expansion joints includes a diode having a first diode terminal and a second diode terminal, a first conductor and a second conductor. The first conductor includes a first terminal that is electrically coupled to the diode at the first diode terminal and a second terminal that is configured as a first expansion joint, which is configured to electrically couple to a first interconnecting-conductor and is configured to reduce a stress applied to the diode by the first conductor. The second conductor includes a first terminal that is electrically coupled to the diode at the second diode terminal and a second terminal that is configured as a second expansion joint, which is configured to electrically couple to a second interconnecting-conductor and is configured to reduce a stress applied to the diode by the second conductor.
US08586856B2	Photovoltaic roofing wiring array, photovoltaic roofing wiring systems and roofs using them Photovoltaic wiring arrays and photovoltaic wiring systems suitable for use in rooftop photovoltaic power generation systems are provided. Accordingly, one aspect of the invention provides a photovoltaic roofing wiring array for use with a plurality of photovoltaic roofing elements, the photovoltaic roofing wiring system including: a positive parallel wiring run comprising a main line and one or more connection branches pendant from the main line, each connection branch being terminated in a positive connector; and a negative parallel wiring run comprising a main line and one or more connection branches pendant from the main line, each connection branch being terminated in a negative connector. In some embodiments of the invention, the photovoltaic roofing wiring arrays are substantially prefabricated.
US08586855B2	Solar cell module A solar cell module having a solar cell panel with strings of electrically-coupled solar cells arranged in a row includes one or more lead wires that electrically couple the strings and a junction box. The one or more lead wires are arranged such that they do not overlap with each other and such that one or more of the lead wires includes a portion that overlaps and does not electrically connect to interconnector of a string. The lead wires include an interconnector connection part connected to a respective string interconnector, and the interconnector connection parts of the lead wires are arranged in a straight line.
US08586853B2	Performance apparatus and electronic musical instrument A performance apparatus 11 extends in its longitudinal direction to be held by a player with his or her hand. The performance apparatus is provided with a geomagnetic sensor 22 and an acceleration sensor 23 in its extending portion. CPU 21 gives an instruction to an electronic musical instrument 19 to generate a musical tone of a tone color at a timing when a position of the performance apparatus obtained by the geomagnetic sensor and acceleration sensor passes through a sound generation area defined in space, wherein the tone color of the musical tone corresponds to the sound generation area. The sound generation areas and corresponding tone colors are stored in an area/tone color table in RAM 26. Upon receipt of an instruction, the electronic musical instrument generates a musical tone having a tone color corresponding to the sound generation area.
US08586850B1	Pickup for stringed musical instruments and related methods of use Disclosed is a pickup assembly for stringed musical instruments with improved acoustic sound quality, and related methods. In one embodiment, the pickup features, three mechanisms for converting the mechanical vibrations of the instrument into an electric signal: first, a mechanism for converting the vibrations of the instruments strings into an electric signal; second, a acoustic chamber mechanism for converting the vibrations of the sound box (e.g. sound waves) into an electric signal; and third, a mechanism for converting the vibrations of the instruments head into an electric signal.
US08586844B2	Under bridge system for guitars An under bridge system is provided having a bridge designed to be secured under the top surface of a guitar and at least one female threaded insert in a top surface of the bridge. The bridge may be adapted to be operationally connected to a saddle on the top surface of the guitar. Each of the at least one threaded inserts is coupled with male threads of a corresponding stud extending downward from the bottom of the saddle through the top surface of the guitar. Each stud is turnable to adjust the height of the saddle above the top surface of the guitar.
US08586841B1	Maize inbred PH1KD3 A novel maize variety designated PH1KD3 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KD3 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1KD3 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1KD3 or a locus conversion of PH1KD3 with another maize variety.
US08586836B1	Soybean cultivar 5101821658 A soybean cultivar designated 5101821658 is disclosed. Embodiments of the invention include the seeds of soybean 5101821658, the plants of soybean 5101821658, to plant parts of soybean 5101821658, and methods for producing a soybean plant produced by crossing soybean 5101821658 with itself or with another soybean variety. Embodiments of the invention include methods for producing a soybean plant containing in its genetic material one or more genes or transgenes and the transgenic soybean plants and plant parts produced by those methods. Embodiments of the invention also relate to soybean cultivars, breeding cultivars, plant parts, and cells derived from soybean 5101821658, methods for producing other soybean cultivars, lines or plant parts derived from soybean 5101821658, and the soybean plants, varieties, and their parts derived from use of those methods. Embodiments of the invention further include hybrid soybean seeds, plants, and plant parts produced by crossing 5101821658 with another soybean cultivar.
US08586835B2	Soybean variety XB25Y11 A novel soybean variety, designated XB25Y11 is provided. Also provided are the seeds of soybean variety XB25Y11, cells from soybean variety XB25Y11, plants of soybean XB25Y11, and plant parts of soybean variety XB25Y11. Methods provided include producing a soybean plant by crossing soybean variety XB25Y11 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB25Y11, methods for producing other soybean varieties or plant parts derived from soybean variety XB25Y11, and methods of characterizing soybean variety XB25Y11. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB25Y11 are further provided.
US08586833B1	Soybean variety XB07Z11 A novel soybean variety, designated XB07Z11 is provided. Also provided are the seeds of soybean variety XB07Z11, cells from soybean variety XB07Z11, plants of soybean XB07Z11, and plant parts of soybean variety XB07Z11. Methods provided include producing a soybean plant by crossing soybean variety XB07Z11 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB07Z11, methods for producing other soybean varieties or plant parts derived from soybean variety XB07Z11, and methods of characterizing soybean variety XB07Z11. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB07Z11 are further provided.
US08586830B2	Ioslated TT1 polynucleotide, encoded proteins and vectors for increasing tolerance of plants and microbes to abiotic stresses and the use thereof The TT1 gene, the recombinant expression vector containing the gene, the polypeptide encoded by the gene and the use thereof are provided. The TT1 gene can effectively increase tolerance of plants and microbes to abiotic stresses, such as drought, acid-alkaline, saline-alkaline and heat. The methods for producing transgenic plants and microbes are also provided. The methods are simple and effective. The transgenic plants and microbes exhibit enhanced tolerance to environmental stresses.
US08586825B2	Nitrogen-regulated sugar sensing gene and protein and modulation thereof The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
US08586824B2	Plant homeodomain protein-encoding genes and their uses A group of genes including GhCIR1 from cotton (Gossypium hirsutum), and AtCIR1 and AtCIR2 from Arabidopsis thaliana promote shoot regeneration in plants even in the absence of cytokinin. In the presence of cytokinin, the genes significantly improve transformation efficiency. The genes can be used as an enhancer as well as a selectable marker of transformation in plants. The proteins encoded by the novel genes have a homeodomain (HD) at the N-terminus and a highly divergent domain at the C-terminus. The proteins share a common structural motif.
US08586821B2	Melt-processed films of thermoplastic cellulose and microbial aliphatic polyester Films made from a thermoplastic cellulose and microbially-derived, renewable and biodegradable aliphatic polyester such as polyhydroxyalkanoates are disclosed. The films, made from two relatively brittle materials exhibit more ductility and strength than the materials from which the film is made. The film may be incorporated into absorbent personal care product including but not limited to training pants, diaper, bandages, and bed pads.
US08586820B2	Absorbent article with colour changing properties An absorbent article such as a diaper, a pant diaper, a sanitary napkin, an incontinence guard etc., which includes thermochromic fibers. The thermochromic fibers may be incorporated in one or more of the following components of the absorbent article: the inner coversheet, the acquisition layer, the absorbent structure, the outer coversheet or a layer arranged between the outer coversheet and the absorbent structure. The article may alternatively contain a fibrous layer which mainly or entirely contains thermochromic fibers. The thermochromic fibers may be used as wetness indicator, as a fever indicator, as a function control for microorganisms that have been incorporated in the article or for amusement purposes, such as creating color imprints of hands etc.
US08586817B2	Method to control acid rock drainage A composition to control acid rock drainage is provided. The composition includes a slurry made from water and solids, the solids containing powders of limestone, clay and magnesium oxide or magnesium hydroxide. In some instances, the slurry is thixotropic and contains between 10 to 75 weight percent of solid powders. The solid powders can include between 40 to 75 weight percent limestone, 10 to 35 weight percent clay and 10 to 30 weight percent magnesium oxide or a proportional concentration of magnesium hydroxide.
US08586815B2	Method for the elimination of oxygen, nitrogen oxides, acetylenes, and/or dienes from hydrogen-rich olefin-containing gas mixtures The present invention relates to a process for removing at least one component selected from the group consisting of oxygen, nitrogen oxides, acetylenes and dienes from a gas mixture comprising the at least one component and also hydrogen, one or more olefins which are not dienes and possibly further gas constituents, in which the gas mixture is brought into contact with a catalyst in a reaction zone, wherein the catalyst comprises copper(I) sulfide.
US08586810B2	Chiral diene ligands, a fabrication method thereof and applications thereof The present invention proposes a chiral diene ligand, a fabrication method thereof and applications thereof. The chiral diene ligand is a bicyclo[2.2.1] diene ligand having structural specificity and high stability, which favors the bicyclo[2.2.1] diene ligand to take part in asymmetric transformations, particularly an asymmetric addition reaction involving a metal catalyst in a basic environment. Most of the products of the reactions implemented by the chiral diene ligands of the present invention have superior optical activity. The method of the present invention comprises a first oxidation step, a saponification step, a second oxidation step, a deprotonation step, and a cross-coupling step. The chiral diene ligand of the present invention is very suitable to be used in the fabrication or synthesis of various chemicals and medical products.
US08586809B2	Purification of transalkylation feedstock A guard bed or absorber is placed upstream of a transalkylation reactor to avoid deposition of halide and/or halogen species on the catalysts in said reactor.
US08586801B2	Cobalt-molybdenum sulfide catalyst materials and methods for stable alcohol production from syngas The present invention provides methods and compositions for the chemical conversion of syngas to alcohols. The invention includes catalyst compositions, methods of making the catalysts, and methods of using the catalysts including techniques to maintain catalyst stability. Certain embodiments teach compositions for catalyzing the conversion of syngas into products comprising at least one C1-C4 alcohol, such as ethanol. These compositions generally include cobalt, molybdenum, and sulfur, and avoid metal carbides both initially and during reactor operation.
US08586800B2	Gas phase hydroformylation process A gas phase catalytic hydroformylation process for producing at least one aldehyde product in the presence of a transition metal-ligand complex hydroformylation catalyst and water vapor. Surprisingly, catalyst activity can be sustained by having traces of water vapor in the feed stream. Additionally, additional ligand can be added to replace lost ligand to maintain activity. In addition, it has been found that treatment of the catalyst with a buffer can rejuvenate catalyst activity.
US08586792B2	Process for the preparation of 4-iodo-3-nitrobenzamide A process for the preparation of 4-iodo-3-nitrobenzamide free from the impurities formed due to nucleophilic substitution of the labile iodo group is disclosed.
US08586788B2	Method for producing of ultra-clean and high-purity electronic grade acetic acid A method for producing of ultra-clean and high-purity electronic acetic acid is disclosed. The method including following steps: Step 1, industrial acetic acid is fast distilled; Step 2, filtering the fraction by membrane of 0.05˜0.3 μm aperture; Step 3, rectification; Step 4, membrane filtration again. Due to the adoption of the technical scheme above, the ultra-clean and high-purity electronic grade acetic acid which purity is 99.8% is produced. The content of single metal ion is lower than 1 ppb and the content of particulates which is ≧0.5 μm is lower than 5 pcs/ml. The method of the invention will help to reduce energy consumption, to simplify the operation, and to achieve the high security.
US08586785B2	Process for producing catalyst for methacrylic acid production and process for producing methacrylic acid An object of the present invention is to provide a process for stably producing a catalyst for methacrylic acid production exhibiting high activity and high performance. The process for producing a catalyst for methacrylic acid production of the invention is characterized in that the water content of the catalyst ingredient powder for use in molding, temperature and humidity of a molding step, humidity and temperature of a baking step are individually controlled in the case where molding is performed by a coating method using an Mo—V—P—Cu-based hetero polyacid as an active ingredient and water or an alcohol and/or an aqueous solution of an alcohol as a binder.
US08586783B2	4-biphenyl-substituted pyrazolidin-3,5-dione derivatives The present invention relates to novel 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to a plurality of processes for the preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) and a crop plant compatibility-improving compound.
US08586777B2	Low VOC coalescing agents A coalescent composition for coating compositions such as paints, adhesives, and coatings comprising a blend of dibasic esters, specifically (i) esters of adipic, glutaric, and/or succinic diacids and/or (ii) esters of isomers of adipic acid have advantages, including efficiency and low VOC.
US08586776B2	GPBP inhibition using Q2 peptidomimetics Disclosed are compounds of formula: that inhibiting GPBP activity, making them useful as therapeutics in antibody-mediated disorders, drug-resistant cancer, inflammation, protein misfolding and ER stress-mediated disorders, and aberrant apoptosis.
US08586775B2	Therapeutic compounds and methods of use Compounds and methods useful for chemopreventative treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, inflammatory bowel diseases, and multiple sclerosis.
US08586771B1	Processes of preparing estolide compounds that include removing sulfonate residues Provided herein are processes of preparing sulfonated estolide compounds, and the removal of sulfonate residues from those compounds to provide desulfonated estolide base oils. Exemplary sulfonated estolide compounds include those selected from the formula: wherein z is an integer selected from 0 to 15; q is an integer selected from 0 to 15; x is, independently for each occurrence, an integer selected from 0 to 20; y is, independently for each occurrence, an integer selected 0 to 20; n is equal to or greater than 0; R6 is selected from —OH, optionally substituted alkyl, and optionally substituted aryl; and R2 is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched, wherein each fatty acid chain residue of said compounds is independently optionally substituted.
US08586769B2	Carrier for ethylene oxide catalysts An improved carrier for an ethylene epoxidation catalyst is provided. The carrier includes an alumina component containing a first portion of alumina particles having a particle size of, or greater than, 3 μm and up to 6 μm, and a second portion of alumina particles having a particle size of, or less than, 2 μm. An improved catalyst containing the above-described carrier, as well as an improved process for the epoxidation of ethylene using the catalyst are also provided.
US08586763B2	Process for producing N-halogenated hydantoins This invention provides a process for the N-halogenation of at least one 5-hydrocarbyl hydantoin and/or at least one 5,5-dihydrocarbyl hydantoin. The process comprises concurrently feeding into a reaction zone (i) water, inorganic base, and 5,5-dimethylhydantoin, these being fed separately and/or in any combination(s), (ii) a separate feed of a brominating agent, and (iii) a separate feed of a chlorinating agent, in proportions such that during all or substantially all of the time the concurrent feeding is occurring halogenation of the 5-hydrocarbyl hydantoin and/or 5,5-dihydrocarbyl hydantoin occurs and resultant halogenated product precipitates in the liquid phase of an aqueous reaction mixture, and in which the pH of the liquid phase is continuously or substantially continuously maintained in the range of about 2.0 to about 8.0 during all or substantially all of the time the concurrent feeding is occurring. Also provided by this invention is a composition of matter which is a halogenated 5-hydrocarbyl hydantoin or a halogenated 5,5-dihydrocarbyl hydantoin, which is a mixture of the 1,3-dibromo-, 1,3-dichloro-, and/or N,N′-bromochloro-species of the halogenated hydantoin.
US08586760B2	Aminothiazole modulators of beta-3-adrenoreceptor The present invention relates to new aminothiazole modulators of beta-3-adrenoreceptor activity, pharmaceutical compositions thereof, and methods of use thereof.
US08586759B2	Methods and systems for synthesis of a D-aminoluciferin precursor and related compounds Methods and systems to generate 6-amino-6-deoxy-D-luciferin precursor, 2-cyano-6-aminobenzothiazole and related compounds and derivatives.
US08586749B2	Compounds that suppress cancer cells and exhibit antitumor activity The present invention provides compounds S3I-201.1066 (Formula 1) and S3I-201.2096 (Formula 2) as selective Stat3 binding agents that block Stat3 association with cognate receptor pTyr motifs, Stat3 phosphorylation and nuclear translocation, Stat3 transcriptional function, and consequently induced Stat3-specific antitumor cell effects in vitro and antitumor response in vivo.
US08586746B2	Amino-aza-adamantane derivatives and methods of use The invention relates to amine-substituted aza-adamantane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.Radiolabelled compounds useful for evaluating the binding affinity to α7 nicotinic acetylcholine receptors also are described.
US08586745B2	Switchable special effect substances A process for altering the absorption of electromagnetic radiation by one or more compounds of the general formulae (I) wherein these compounds are irradiated with electromagnetic radiation of wavelength from 300 to 750 nm. The use of compounds of the general formula (I) or (II) for marking materials, for example paper or mineral oil, and use of compounds of the general formula (I) or (II) for causing a color change. The use of compounds of the general formula (I) or (II) for laser welding, heat management, as a photoinitiator, as a free-radical scavenger or for detection of oxygen. A process for regulating the absorption or transmission of electromagnetic radiation by a material wherein one or more compounds of the general formula (I) or (II) are contacted with this material and these compounds are irradiated with electromagnetic radiation of wavelength from 300 to 750 nm. Specific compounds of the general formula (I).
US08586744B2	Antiviral phosphinate compounds The invention is related to a method of treating disorders associated with hepatitis C by administering to an individual a pharmaceutical composition which comprises a therapeutically effective amount of an anti-viral phosphinate compound.
US08586743B2	Labeling reagents and methods of their use The present disclosure is directed to a reactive ester agent capable of conjugating a reporter molecule to a carrier molecule or solid support. The reactive ester agent has the general formula: wherein the variables are described throughout the application.
US08586742B2	Process for preparing amines from alcohols and ammonia The present invention provides novel ruthenium based catalysts, and a process for preparing amines, by reacting a primary alcohol and ammonia in the presence of such catalysts, to generate the amine and water. According to the process of the invention, primary alcohols react directly with ammonia to produce primary amines and water in high yields and high turnover numbers. This reaction is catalyzed by novel ruthenium complexes, which are preferably composed of quinolinyl or acridinyl based pincer ligands.
US08586740B2	Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device using quinoxaline derivative Provided is a compound represented by the following formula (G21). Further, provided is a light-emitting element including a layer including a compound represented by the following formula (G21) between a pair of electrodes. In the formula (G21), two pyridine skeletons are respectively bonded to 2-position and 3-position of a quinoxaline skeleton arylene groups.
US08586737B2	Process of a quaternary ammonium salt using phosphate The present invention relates to a novel process for preparing quaternary ammonium salt derivatives.
US08586736B2	Perimidine-based squarylium dye, dye-containing composition, and image-forming material A perimidine-based squarylium dye contains a compound represented by Formula (I), the compound containing an isomer A and satisfying the following formula: Pa≧95(%) wherein the isomer A is an isomer of the peak shown in the longest retention time among all peaks due to isomers obtained by analysis of the compound by means of reversed-phase high-performance liquid chromatography, and Pa represents a value of the peak area of the isomer A relative to the peak area of all peaks.
US08586733B2	Processes and intermediates for making sweet taste enhancers The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.
US08586732B2	Fused heterocyclic compounds as ion channel modulators The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein Z1, Z2, Z3, Z4, X, Y, R2, R3 and R4 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
US08586725B2	MicroRNAome MicroRNAs (miRNAs) are a class of small noncoding RNAs that have important regulatory roles in multicellular organisms. The public miRNA database contains 321 human miRNA sequences, 234 of which have been experimentally verified. To explore the possibility that additional miRNAs are present in the human genome, we have developed an experimental approach called miRNA serial analysis of gene expression (miRAGE) and used it to perform the largest experimental analysis of human miRNAs to date. Sequence analysis of 273,966 small RNA tags from human colorectal cells allowed us to identify 200 known mature miRNAs, 133 novel miRNA candidates, and 112 previously uncharacterized miRNA* forms. To aid in the evaluation of candidate miRNAs, we disrupted the Dicer locus in three human colorectal cancer cell lines and examined known and novel miRNAs in these cells. The miRNAs are useful to diagnose and treat cancers.
US08586719B2	Triterpenes for modulating gene expression and cell membrane, and as antiprotozoal agents This invention provides methods, processes, compounds and compositions for modulating the gene expression or secretion of adhesion proteins, angiopoietins or their receptors to cure diseases, for anti-angiogenesis and for treating parasites, wherein the adhesion proteins or receptors comprise fibronectin, integrins family, myosin, vitronectin, collagen, laminin, glycosylation cell surface proteins, polyglycans, cadherin, heparin, tenascin, CD 54 , CAM, elastin and FAK; wherein the angiopoietins comprise angiopoietin 1, angiopoietin 2, angiopoietin 3, angiopoietin 4, angiopoietin 5, angiopoietin 6, angiopoietin 7, angiopoietin-like 1, angiopoietin-like 2, angiopoietin-like 3, angiopoietin-like 4, angiopoietin-like 5, angiopoietin-like 6, and angiopoietin-like 7; wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, prostate cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, CNS cancer, melanoma cancer, renal cancer, cervical cancer, esophageal cancer, testicular cancer, spleenic cancer, kidney cancer, lymphatic cancer, pancreas cancer, stomach cancer and thyroid cancer.
US08586718B2	Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes Dark quencher constructs, termed “multi-chromophoric quenchers” are described herein that comprise at least two dark quenching moieties, which can be the same or different, linked together by at least one multivalent linking moiety. The structure of the multi-chromophoric quenchers can be varied to selectively enhance quenching within a specific range of reporter emission wavelengths. This can be accomplished by linking together, into a single molecule, two or more identical quenchers, by reacting the quenchers with a multivalent linker. The structure of the multi-chromophoric quencher can also be varied to quench a broader range of reporter emission wavelengths than previously possible. This can be accomplished by linking together, into a single molecule, two or more different quenchers, by reacting the quenchers with a multivalent linker. The structure of the multi-chromophoric quencher can also be varied to simultaneously broaden the absorption range and increase the total absorption within the absorption range. This can be done by combining the two concepts described above. In other words, multiple types of quenching moieties can be employed to increase the absorption range and a multiple number of each type of quenching moiety can be used to increase the total absorptivity within the absorption range. The multi-chromophoric quenchers can be tethered to probes for biomolecules, insoluble supports and/or fluorescent dyes for use in a wide variety of biomolecular assays.
US08586717B2	Method for the diagnosis and prognosis of malignant diseases Methods for the treatment of tumors and cancer by exploiting the surface expression of the usually nuclear-localized protein, nucleolin.
US08586716B2	EPHB3-specific antibody and uses thereof EphB3-specific antibodies are provided, along with pharmaceutical compositions containing such antibody, kits containing a pharmaceutical composition, and methods of preventing and treating cancer.
US08586715B2	Humanized anti-CD4 antibody with immunosuppressive properties A humanized antibody derived from mouse monoclonal anti-CD4 antibody B-F5 is able to activate CD25+CD4+ regulatory T cells and is useful for preparing immunosuppressive compositions.
US08586710B2	Process for gram scale production of PEG-r-metHuG-CSF The present invention relates to a process for improving pegylation reaction yield of r-metHuG-CSF comprising conjugating r-metHuG-CSF to a PEG aldehyde at a free amine moiety at the N terminal end on the G-CSF in presence of a reducing agent in a pegylation buffer solution comprising a polyol having the formula CnH2n+2On where n is from 3 to 6, or a carbohydrate, or a derivative thereof wherein the concentration of said polyol or carbohydrate or derivative thereof is in the range of 0.1% to 10% w/w.
US08586708B2	Monovalent streptavidin compositions The invention relates, in part, to monovalent streptavidin compositions. The invention also relates to methods of preparing and using monovalent streptavidin compositions. In some aspects of the invention, the compositions are monovalent streptavidin with a single femtomolar biotin-binding site.
US08586705B2	Macromolecular compounds having controlled stoichiometry The following invention is directed to macromolecules having controlled stoichiometry and topology, processes for their production, and applications for their use. The macromolecules have a controlled functional moiety stoichiometry and include at least one dendritic motif having a surface layer formed from at least one surface building unit and at least one subsurface layer formed from at least one building unit, the surface building unit and building units having a hydrocarbon backbone bearing a carbonyl group and at least one amine group; and at least two different functional moieties on the building unit and/or surface building unit; where functional moiety stoichiometry refers to the number and type of functional moieties.
US08586700B2	Method for preparing a poly(ether sulfonimide or -amide) copolymer using cyclic oligomers Disclosed is a method for preparing a poly(ethersulfonimide or ethersulfonamide) copolymer using cyclic oligomers, and more particularly, to a method for preparing a poly(ethersulfonimide or ethersulfonamide) copolymer by preparing a cyclic ether sulfone oligomer and a cyclic imide or amide oligomer and subjecting the cyclic ether sulfone oligomer and the cyclic imide or amide oligomer to ring-opening copolymerization in the presence of an alkali metal fluoride catalyst.
US08586699B2	Phosphorus-containing compounds useful for making halogen-free, ignition-resistant polymers Phosphorus-containing compounds useful for flame retardant epoxy resins are disclosed. The flame retardant epoxy resins may be used to make electrical laminates. This invention is particularly useful in end use applications in which a low bromine or low halogen content is required or desired.
US08586697B2	Coatings repairable by introduction of energy The present invention relates to coating compositions repairable by introduction of energy and comprising defined fatty acid esters, to coatings obtained therewith and repairable by introduction of energy, to methods of producing them, and to their use.
US08586693B2	Superhydrophobic coating A composition for coating comprising at least one compound of formula I and optionally at least one compound of formula II RaSi(R1)n(X1)3-n I RbSi(R2)m(X2)3-m II wherein Ra is a straight-chain or branched C(1-24) alkyl group, Rb is an aromatic group, such as an optionally substituted carbocyclic and heterocyclic group comprising five-, six- or ten-membered ring systems, which is linked by a single covalent bond or a spacer unit, such as a straight-chain or branched alkyl residue having 1 to 8 carbon atoms, to the Si— atom, R1 and R2 are independently of each other a lower alkyl group, such as a straight chain and branched hydrocarbon radical having 1 to 6 carbon atoms, X1 and X2 are independently of each other a hydrolysable group, such as a halogen or an alkoxy group and n, m are independently of each other 0 or 1, with the proviso that if n and m are independently of each other 0 or 1, X may represent the same or different groups.
US08586691B2	Method of making a blocked polymer with a siloxane linking group Carbanionic polymer chains that contain polyene mer can be provided with a block derived from one or more ethylenically unsaturated functional monomers after being reacted to include, at their respective termini, one or more, although preferably one, unit that is the radical of a cyclic compound, the ring structure of the cyclic compound comprising silicon atoms alternating with O, S or N atoms.
US08586689B2	Polymer, and composition and film including the same A polymer including a structural unit represented by the following Chemical Formula 1, and a composition and a film including the same are provided. In the above formula at least one of Ra and Rb is either Chemical Formula 3 or Chemical Formula 4, as shown below. The polymer also includes units selected from polyamic acid, polyimide, polyaramid, polyamide, polyurethane, polycarbonate and polyacetal units and mixtures of such units.
US08586688B2	Curable composition and method for improving recovery properties and creep properties Disclosed are a curable composition characterized by using a curable composition including an organic polymer (A1) having one or more silicon-containing functional groups capable of cross-linking by forming siloxane bonds in which the one or more silicon-containing functional groups capable of cross-linking by forming siloxane bonds are silicon-containing functional groups each having three or more hydrolyzable groups on one or more silicon atoms thereof; and a method for controlling the recovery properties, durability and creep resistance of the cured article. Herewith, the present invention provides a curable composition capable of giving a cured article excellent in recovery properties, durability and creep resistance, and a method for controlling the recovery properties, durability and creep resistance of the cured article.
US08586687B2	Polyalkylene glycol-based polymer and process for producing the same The present invention has an object to provide a polyalkylene glycol-based polymer having high anti-soil redeposition ability in washing treatment and having high compatibility with surfactants. The polyalkylene glycol-based polymer includes: a structure unit (a) derived from a polyalkylene glycol-based monomer (A) of a specific structure, and a structure unit (b) derived from a carboxyl group-containing monomer (B) at specific ratios.
US08586684B2	Conjugated copolymer The invention relates to a conjugated copolymer comprising indenofluorene and triarylamine units and to its use in organic electronic devices.
US08586680B2	Rubber composition for golf ball and golf ball The object is to provide a rubber composition for a high-strength golf ball which has a high hardness, high resiliency, excellent processability and improved filler dispersibility, by adjusting each of the Mooney viscosity, the molecular weight distribution and the n value (the rate-dependent index for Mooney viscosity) of a high-cis-polybutadiene rubber using a cobalt catalyst to a value falling within a specific range. The rubber composition comprises 100 parts by weight of a high-cis-polybutadiene synthesized using a cobalt catalyst and 10 to 50 parts by weight of a co-crosslinking agent, wherein the high-cis-polybutadiene satisfies the following requirements (a) to (c): (a) the Mooney viscosity (ML) is 40 to 55; (b) the molecular weight distribution [a weight average molecular weight MW)/a number average molecular weight (Mn)] is 3.0 to 4.2; and (c) the rate-dependent index of Mooney viscosity (n value) is 2.3 to 3.0.
US08586679B2	Resin composition suitable for (re) lining of tubes, tanks and vessels The present invention relates to structural, radically curable resin compositions suitable for (re)lining containing a. 30-70 wt. % of a resin characterized by (i) a molecular weight Mn between 500 and 3000 and (ii) an acid value between 0 and 30 mg KOH/g resin, and wherein at least 80 % of the total amount of resin is vinyl ester resin, b. 30-70 wt. % of at least one reactive diluent, characterized in that at least 25% of the reactive diluent is a difunctional diluent having a molecular weight Mn between 200 and 500 and the optional monofunctional diluent having a molecular weight Mn between 100 and 200, c. 0.00001-5 wt. % initiator, d. 0.00001-5 wt. % inhibitor further characterized in that the average molecular weight per reactive unsaturation (WPU) of the components (a) and (b) is equal or greater than 190 Dalton and that the amount of styrene in the resin composition is less than 5 wt. % (calculated as wt. % of the total weight of the components (a), (b), (c) and (d)).
US08586678B2	Blends of linear and branched neodymium-catalyzed rubber formulations for use in golf balls The invention relates to golf ball formulations formed from blends of linear and branched polybutadienes catalyzed with neodymium that have improved properties and processing characteristics. Golf ball components may be formed from the blends to provide high coefficient of restitution.
US08586674B2	Copolymer rubber composition, molded product, and automotive sealant The copolymer rubber composition comprises 60 to 75% by weight of a copolymer rubber (1) and 40 to 25% by weight of a copolymer rubber (2), and exhibits a difference in iodine value of 5 to 30 between the copolymer rubber (1) and the copolymer rubber (2). The copolymer rubber (1) is an ethylene-α-olefin-nonconjugated polyene copolymer rubber having an ethylene unit of 50 mol % to 70 mol %, an α-olefin unit of 50 mol % to 30 mol %, and an iodine value of 10 to 30, and the copolymer rubber (2) is an ethylene-α-olefinic copolymer rubber having an ethylene unit of more than 70 mol % and 95 mol % or less, an α-olefin unit of less than 30 mol % and 5 mol % or more, and an iodine value of 0 to 8.
US08586673B2	Fire resistant, high flow poly(aryl ether sulfone) composition Polymer composition (C) containing (i) a poly(aryl ether sulfone) material (M12) composed of a poly(biphenyl ether sulfone) (P1) and, optionally in addition, a poly(aryl ether sulfone) (P2) containing recurring units with arylene groups linked to each other via a secondary, ternary or quaternary carbon atom, and (ii) a per(halo)fluoropolymer material (M34), composed of a per(halo)fluoropolymer (P3) of which at least 2.0 wt. % of the recurring units are derived from a per(halo)fluoromonomer other than tetrafluoroethylene, and a polytetrafluoroethylene (P4). Shaped article, especially aircraft interior component, comprising the polymer composition (C).
US08586672B2	Method for increasing polymer compatibility The invention relates to a method for increasing the compatibility between at least two polymers, which comprises: (a) selecting at least two immiscible polymers (A) and (B), at least one of which does not bear a nitrogenous heterocycle-based associative group, and (b) modifying the polymer (A) and/or the polymer (B) so as to obtain a blend of polymers (Pi) which are derived from the polymers (A) and (B) and which each bear nitrogenous heterocycle-based associative groups, said associative groups being present in sufficient amount for the polymers (Pi) to be more compatible with one another than the polymers (A) and (B). It also relates to the polymer composition that can be obtained according to this method.
US08586671B2	Biocompatible phase invertible proteinaceous compositions and methods for making and using the same Biocompatible phase invertible proteinaceous compositions and methods for making and using the same are provided. Phase invertible compositions in accordance with the invention are prepared by combining a liquid proteinaceous substrate and a liquid crosslinking composition, where the liquid crosslinking composition includes a macromolecular crosslinking agent. Also provided are kits for use in preparing the subject compositions. The subject compositions, kits and systems find use in a variety of different applications.
US08586669B2	Silicone paste compositions Silicone paste compositions are disclosed by combining a silicone organic elastomer gel with water or a hydrophilic solvent. The silicone paste compositions may further contain a personal or healthcare active. The silicone organic elastomer gel is prepared by reacting in a carrier fluid an organohydrogensiloxane with two polyoxyalkylenes, the first polyoxyalkylene having aliphatic unsaturation at both each molecular termini, and the second polyoxyalkylene having aliphatic unsaturation at one molecular terminal.
US08586668B2	Polydiorganosiloxane polyoxamide copolymers Polydiorganosiloxane polyoxamide, linear, block copolymers and methods of making the copolymers are provided. The method of making the copolymers involves reacting a diamine with a precursor having at least one polydiorganosiloxane segment and at least two oxalyamino groups. The polydiorganosiloxane polyoxamide block copolymers are of the (AB)n type.
US08586663B2	Polymer composition comprising polyamide and ionomer Disclosed in a composition comprising at least one ionomer (A) and at least one blend comprising at least one polyamide and at least one ionomer (B) wherein the polyamide is an aliphatic polyamide and the ionomer (B) is a copolymer of ethylene, an α, β-unsaturated C3-C8 carboxylic acid, at least one ethylenically unsaturated dicarboxylic acid or derivative thereof, and optionally an alkyl (meth)acrylate.
US08586661B2	Surface covering materials and products In various embodiments, the present inventions provide a heat and color stable flooring materials/product comprising between about 1 wt % to about 50 wt % a polyolefin-based elastomer material; between about 2 wt % to about 50 wt % a polyolefin-based thermoplastic material; between about 20 wt % to about 75 wt % a filler; and between about 0.25 wt % to about 5 wt % a curing system containing a peroxide. Also provided in various embodiments are method of making and using such a flooring material/product.
US08586657B2	Aqueous fire-retardant non-corrosive composition for topical application to products and articles Disclosed is a fire-retardant, non-corrosive, insect-resistant, fungus-resistant composition comprising a first flame-retardant agent, a preservative composition, a second flame-retardant agent, a third flame-retardant agent, and a liquid melamine formaldehyde resin adhesive. The composition is to be used for topical application to articles using a spray device, where a layer of a desired thickness is applied.
US08586656B2	Ink composition for inkjet printing An ink composition for ink-jet printing does not cause clogging of nozzles of an ink-jet printer during printing, thereby providing a print of desired printing quality; which ensures an appropriate drying rate of printed images; and which attains excellent color development. The ink composition for ink-jet printing, containing a pigment, a binder resin, a pigment dispersant, and a solvent, wherein the solvent is formed of (1) at least one glycol ether and at least one of a lactone compound and 2-pyrrolidone, or (2) at least one glycol ether acetate and at least one of cyclohexane and isophorone.
US08586653B2	Curing of epoxy resin compositions comprising cyclic carbonates using mixtures of amino hardeners A process for curing an epoxy resin composition containing an epoxy resin and a compound of the general formula I: where R1 and R2 independently are hydrogen, C1-C6-alkyl, C1-C4-alkoxy-C1-C4-alkyl, C5-C6-cycloalkyl, phenyl, phenyl-C1-C4-alkyl, C2-C6-alkenyl or C2-C6-alkynyl, or R1 and R2 together are a C3-C11-alkylene group; and where R3 and R4 independently are hydrogen, C1-C6-alkyl, C1-C4-alkoxy-C1-C4-alkyl, C5-C6-cycloalkyl, phenyl, phenyl-C1-C4-alkyl, C2-C6-alkenyl or C2-C6-alkynyl, or R3 and R4 together are a C4-C6-alkylene group. The process includes adding amino hardeners, where 0.1% to 50% by weight of the amino hardeners are aliphatic, cycloaliphatic or aromatic amine compounds having 1 to 4 primary amino groups and optionally further functional groups, selected from secondary amino groups, tertiary amino groups, and hydroxyl groups. In the case of the cycloaliphatic and aromatic amine compounds, the primary amino groups are attached as aminomethylene groups (H2N—CH2—) to the cycloaliphatic or aromatic ring system (referred to below for short as co-hardeners).
US08586651B2	Elastomer composite and method for producing it A method of producing an elastomer composite. The method includes A) combining a first fluid comprising elastomer latex with a second fluid comprising particulate filler; B) causing the elastomer latex to coagulate, thereby forming masterbatch crumb; C) bringing the masterbatch crumb to a water content of about 1 weight percent to about 20 weight percent, thereby forming a dewatered coagulum; D) removing water from the dewatered coagulum by subjecting the dewatered coagulum to mechanical energy, thereby causing the dewatered coagulum to heat as a result of friction, while allowing the dewatered coagulum to achieve a temperature of about 130° C. to about 190° C., wherein water content is reduced to about 0.5% to about 3% and wherein substantially all of the decrease in water content is accomplished by evaporation, thereby producing a masticated masterbatch; and E) subjecting the masticated masterbatch to at least an additional 0.3 MJ/kg of mechanical energy while further reducing the water content.
US08586644B2	Photocurable composition suitable for rust prevention of a threaded joint for steel pipes A thin and highly transparent coating having excellent air tightness, adhesion to a substrate, lubricating properties, galling resistance, and corrosion resistance is formed on the surface of a metal substrate and particularly on the surface of a threaded joint which is used for connection of oil country tubular goods. A photocurable composition comprising (A) a photocurable (meth)acrylate resin, (B) a (meth)acrylate monomer selected from a monofunctional (meth)acrylate monomer and a difunctional (meth)acrylate monomer, (C) a trifunctional or higher multifunctional (meth)acrylate monomer, (D) a photopolymerization initiator, (E) a benzotriazole anticorrosive agent, (F) an anticorrosive pigment selected from a phosphate anticorrosive pigment and calcium ion-exchanged silica, and (G) a phosphate ester is used to form a photocured coating.
US08586640B2	Hydrocarbon synthesis reaction apparatus, hydrocarbon synthesis reaction system, and hydrocarbon synthesizing method A hydrocarbon synthesis reaction apparatus which synthesizes a hydrocarbon compound by a chemical reaction of a synthesis gas including hydrogen and carbon monoxide as the main components, and a slurry having solid catalyst particles suspended in a liquid, the hydrocarbon synthesis reaction apparatus is provided with: a reactor which contains the slurry; a synthesis gas introduction part which introduces the synthesis gas into the reactor; and a synthesis gas heating part which is provided in the synthesis gas introduction part to heat the synthesis gas introduced into the reactor to the decomposition temperature of carbonyl compounds or higher.
US08586638B2	Parakeratosis inhibitor and skin preparation for external use To provide a parakeratosis inhibitor, pore reducing agent and skin roughness preventing/ameliorating agent that exhibit capabilities of parakeratosis inhibition, pore reduction, skin roughness prevention/amelioration, etc., and further provide a skin preparation for external use having these capabilities. There are provide a parakeratosis inhibitor and a pore reducing agent each comprising at least one compound selected from the group consisting of a glycine derivative, an aminodicarboxylic acid derivative, an acylaminodicarboxylic acid derivative, a pyrrolidinecarboxylic acid derivative, a piperidinecarboxylic acid derivative, a hexamethyleneiminecarboxylic acid, a beta-alanine derivative and salts of these derivatives. Further, there are provided a parakeratosis inhibitor, a pore reducing agent and a skin roughness preventing/ameliorating agent each comprising at least one compound selected from the group consisting of specified glycine derivatives and salts thereof and specified aminosulfuric acid derivatives and salts thereof. Still further, there are provided skin preparations for external use comprising these compounds.
US08586635B2	Antifungal compositions for inhibiting growth of wood decay fungi and use thereof The present invention is related to an antifungal composition for the inhibition of wood decay caused by wood rot fungi. The invention further comprises a method for the inhibition of wood decay with gallates.
US08586633B2	Ophthalmologic irrigation solutions and method Solutions for perioperative intraocular application by continuous irrigation during ophthalmologic procedures are provided. These solutions include multiple agents that act to inhibit inflammation, inhibit pain, effect mydriasis (dilation of the pupil), and/or decrease intraocular pressure, wherein the multiple agents are selected to target multiple molecular targets to achieve multiple differing physiologic functions, and are included in dilute concentrations in a balanced salt solution carrier.
US08586632B2	Use of the irritating principal oleocanthal in olive oil, as well as structurally and functionally similar compounds The invention provides oleocanthal analogs and methods of using oleocanthals in various formulations including, food additives; pharmaceuticals; cosmetics; animal repellants; and discovery tools for mammalian irritation receptor genes, gene products, alleles, splice variants, alternate transcripts and the like.
US08586630B2	Enhanced bimatoprost ophthalmic solution A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein.A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
US08586625B2	Derivatives of taxol and closely related compounds A cytotoxic composition in which two moieties are conjugated covalently. A first moiety is a tax moiety, selected from the group consisting of taxanes, taxane derivatives, and or other closely relative compounds. A second moiety is an acid moiety selected from the group consisting of lipoic acid, acetylcysteine, compounds having an acidic group.
US08586621B2	Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles The present invention includes methods and compositions for the treatment and prevention of protozoal parasitic infections utilizing Diindolylmethane-related indoles. Additive and synergistic interaction of Diindolylmethane-related indoles with other known anti-parasitic and pro-apoptotic agents is believed to permit more effective therapy and prevention of protozoal parasitic infections. The methods and compositions described provide new treatment of protozoal parasitic diseases of mammals and birds including malaria, leishmaniasis, trypanosomiasis, trichomoniasis, neosporosis and coccidiosis.
US08586620B2	Substituted indole compounds having NOS inhibitory activity The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, morphine/opioid induced tolerance and hyperalgesia.
US08586617B2	Aminomethyl-4-imidazoles The present invention relates to amino-4-methyl imidazoles and pharmaceutically-acceptable salts thereof. The compound may be used for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders such as schizophrenia, neurological diseases such as Parkinson's disease, neurodegenerative disorders such as Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse and metabolic disorders such as eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
US08586614B2	Urea glucokinase activators The invention provides a compound of general formula (I) wherein the substituents are defined further in the application, as well as further embodiments hereof described in the attached embodiments. The present invention also provides use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes.
US08586613B2	Pyridinium and quinolinium derivatives The invention provides compounds of formula I blocking phosphorylcholine biosynthesis by means of the selective blocking of the choline kinase enzyme in tumor cells or in cells affected by parasitic infection and therefore being applicable in the treatment of tumors and parasitic diseases or diseases produced by viruses and fungi in animals, including human beings; as well as to a method for preparing the compounds of the invention and certain intermediates of said method.
US08586612B2	Piperidinesulfonylureas and -thioureas, their preparation, their use and pharmaceutical compositions comprising them The present invention relates to piperidinesulfonylureas and piperidinesulfonylthioureas of formula I, in which A, X, R(1), R(2) and R(3) have the meanings indicated in the claims. The compounds of formula I are valuable active pharmaceutical ingredients which show in particular an inhibiting effect on ATP-sensitive potassium channels of the cardiac muscle and are suitable, for example, for the treatment of disorders of the cardiovascular system such as coronary heart disease, arrhythmias, cardiac insufficiency, cardiomyopathies or reduced contractility of the heart or for the prevention of sudden cardiac death. The invention further relates to processes for preparing the compounds of formula I, their use and pharmaceutical compositions comprising them.
US08586610B2	Methods for the administration of iloperidone The present invention relates to methods for the identification of genetic polymorphisms that may be associated with a risk for QT prolongation after treatment with iloperidone and related methods of administering iloperidone to patients with such polymorphisms.
US08586602B2	Derivatives of 7 alkynyl-1,8 naphthyridones, preparation method thereof and use of same in therapeutics The disclosure relates to method of treating a disease in which VEGFR-3 is involved, comprising administering a therapeutically effective amount of a compound of the formula wherein R1, R2, R3, and R4 are as defined in the disclosure, to compositions containing them, to processes for preparing them, and to their use in therapeutics.
US08586599B2	Polymorphic forms of 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-2-yl]-benzyl}-2H-pyridazin-3-one dihydrogenphosphate and processes of manufacturing thereof The present invention relates to 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-2-yl]-benzyl}-2H-pyridazin-3-one dihydrogenphosphate, its solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer.
US08586597B2	6-fluoro-3-phenyl-2-[1-(9H-purin-6-ylamino)ethyl]-3H-quinazolin-4-one as an inhibitor of human phosphatidylinositol 3-kinase delta Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform PI3Kδ activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed. An exemplary compound disclosed in this application is shown below.
US08586589B2	Piperidine and piperazine phenyl sulfonamides as modulators of ion channels The present invention relates to piperidine and piperazine phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.
US08586586B2	Methods and compositions for treating or preventing erythema Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one α-adrenergic receptor agonist and a pharmaceutically acceptable carrier.
US08586585B2	Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes and Parkinson's disease Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.
US08586584B2	Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
US08586583B2	Compounds The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): And salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
US08586581B2	Ethynyl compounds useful for treatment of CNS disorders The present invention relates to ethynyl compounds of formula wherein X, Y, Z, and R4 are as defined herein or to a pharmaceutically acceptable salt or acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof. Compounds of formula I are positive allosteric modulators (PAM) of the metabotropic glutamate receptor subtype 5 (mGluR5) and they are therefore useful for the treatment of diseases related to this receptor.
US08586579B2	Anellated pyridine compounds The present invention is concerned with novel dual modulators of the 5-HT2A and D3 receptors of formula (I) wherein X, Y, A, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as therapeutics.
US08586574B2	Benzoxazepin PI3K inhibitor compounds and methods of use Benzoxazepin compounds of Formula I, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, wherein: Z1 is CR1 or N; Z2 is CR2 or N; Z3 is CR3 or N; Z4 is CR4 or N; and B is a pyrazolyl, imidazolyl, or triazolyl ring fused to the benzoxepin ring, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
US08586573B2	N-(Aminoheteroaryl)-1H-indole-2-carboxamide derivatives, and preparation and therapeutic application thereof The invention concerns compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z, Z1, Z2, Z3 and Z4 are as defined herein. The invention also concerns a process for the preparation of compounds of formula (I) and their therapeutic use.
US08586572B2	3-phenyl-azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission The present invention relates to novel 3-phenyl-azetidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-azetidine derivatives of the invention and to the use of these compounds for therapeutic applications.
US08586571B2	Heterocyclic compound The present invention relates to wherein each symbol is as defined in the specification. The compound of the present invention has a superior RBP4-lowering action, and is useful as a medicament for the prophylaxis or treatment of disease and condition mediated by increased RBP4.
US08586570B2	Sox-based kinase sensor Peptidyl sensors comprise a metal-binding peptide and one or two kinase recognition sequences with a hydroxyamino acid that can be phosphorylated in the presence of a kinase.
US08586563B2	Nutritional composition containing oligosaccharide mixture A nutritional composition for administration to an infant which composition comprises, on a dry matter basis, from 2.5 to 15.0 wt % of an oligosaccharide mixture consisting of N-acetylated oligosaccharide(s), galacto-oligosaccharide(s) and sialylated oligosaccharide(s) with the proviso that the composition comprises at least 0.02 wt % of an N-acetylated oligosaccharide, at least 2.0 wt % of a galacto-oligosaccharide and at least 0.04 wt % of a sialylated oligosaccharide and that the N-acetylated oligosaccharide(s) comprise 0.5 to 4.0% of the oligosaccharide mixture, the galacto-oligosaccharide(s) comprise 92.0 to 98.5% of the oligosaccharide mixture and the sialylated oligosaccharide(s) comprise 1.0 to 4.0% of the oligosaccharide mixture. The composition is useful for administration to an infant in the first six months of life to reduce the risk of obesity later in life.
US08586552B2	4,6-substituted 2,5-dideoxystreptamine aminoglycoside antibiotics Aminoglycoside antibiotics of the formula are disclosed. The compounds are useful for treating bacterial infections, particularly infections resistant to known antibiotics.
US08586551B2	18-membered macrocycles and analogs thereof The present invention relates generally to the 18-membered macrocyclic antimicrobial agents called Tiacumicins, specifically, OPT-80 (which is composed almost entirely of the R-Tiacumicin B), pharmaceutical compositions comprising OPT-80, and methods using OPT-80. In particular, this compound is a potent drug for the treatment of bacterial infections, specifically C. difficile infections.
US08586546B2	Combined treatment with an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors The present invention provides a method for treating tumors or tumor metastases in a patient, comprising administering to said patient simultaneously or sequentially a therapeutically effective amount of a combination of an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors, wherein said agent is an mTOR inhibitor that binds to and directly inhibits both mTORC1 and mTORC2 kinases. The present invention also provides a pharmaceutical composition comprising an EGFR kinase inhibitor and an mTOR inhibitor that binds to and directly inhibits both mTORC1 and mTORC2 kinases, in a pharmaceutically acceptable carrier. A preferred example of an EGFR kinase inhibitor that can be used in practicing the methods of this invention is the compound erlotinib HC1 (also known as TARCEVA®).
US08586545B2	Solid materials of {[(2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acid} and methods for obtaining them The instant invention relates to novel solid materials of {[(2S,5R,8S,11S)-5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid}, methods for producing them, and the use of said solid materials in pharmaceuticals.
US08586539B2	Beta sheet tapes ribbons in tissue engineering There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a β-sheet tape-like substructure.
US08586537B2	Method for treating minor aphthous ulcers A method for treating recurrent minor aphthous ulcers is provided in which a sufferer is treated with a combination therapy of Vitamin B6 and B12 compounds. The treatment is done orally and the treatment minimizes the duration and pain of the sore, as well as increasing the period of time between recurrences.
US08586536B2	Neprilysin inhibitors In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
US08586533B2	Treatment of early-stage osteoarthritis A method for treating early-stage osteoarthritis in an animal is provided. The method comprises delivery of a therapeutically effective amount of a parathyroid hormone (PTH) or a PTH derived substance to an affected joint cavity of the patient. Methods for inhibiting articular chondrocytes apoptosis and for inhibiting a degenerative process of articular chondrocytes in an afflicted animal are also provided.
US08586530B2	Modulation of inhibition of ferrochelatase by N-methyl protoporphyrin Provided herein, is a means for development of ferrochelatase variants with improved tolerance towards N-methyl protoporphyrin. Also disclosed are cell assay systems utilizing the variants, as the variants would confer resistance to N-methyl protoporphyrin inhibition and thereby keep heme synthesis uninterrupted. The variants contain loop mutations that affect the NMPP-ferrochelatase interaction, and different degrees of NMPP tolerance are obtained with the introduction of loop mutations in wild-type ferrochelatase. Also disclosed is kinetic mechanism of inhibition of ferrochelatase by NMPP, using the disclosed variants whose mutations in the “porphyrin-interacting loop” motif weakened the potency of NMPP as an inhibitor.
US08586528B2	Biologically active peptides and their new uses Novel peptides are disclosed with their use as a pharmaceutical composition. A method is also disclosed for making pharmaceutical compositions and treatment of an individual.
US08586526B2	DNA-binding proteins and uses thereof Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
US08586524B2	Modulators of pharmacological agents The biological activity of nucleic acid ligand is regulated (i.e. enhanced or inhibited) in vivo to produce a desired biological effect. This is accomplished through the administration of a modulator, or regulator, that changes the binding of the nucleic acid ligand for its target or that degrades or otherwise cleaves, metabolizes or breaks down the nucleic acid ligand while the ligand is still exerting its effect. Modulators of the present invention can be administered in real time as needed based on various factors, including the progress of the patient, as well as the physician's discretion in how to achieve optimal therapy. Thus, this invention provides for the first time a regulatable therapeutic regime in the course of nucleic acid ligand therapy.
US08586523B2	Sulfonate group-containing copolymers and manufacturing method thereof [Problem] To provide detergent compositions with superior surfactant deposition-inhibiting ability and anti-gelling properties that exhibit good cleaning effectiveness even when laundering under harsh conditions such as laundering in residual bath water. [Solution] A laundry detergent or cleaning composition which comprises a copolymer containing sulfonate groups containing from 1 to 50 mass percent of structural units (a) derived from 1 or more kinds of monomers (A) selected from ether bond-containing monomers represented by Formulas (1) and (2), 50 mass % or more and less than 98 mass % of structural units (b) derived from a carboxyl group-containing monomer (B), and 1 mass % or more and less than 50 mass % of structural units (c) de-rived from a sulfonate group-containing monomer (C).
US08586522B2	Glycol dilevulinates as coupling agents in cleaning formulations The present invention provides water-based cleaning formulations comprising one or more organic solvents having low solubility in water and an alkylene glycol dilevulinate for coupling the organic solvent with water.
US08586519B2	Multi-grade engine oil formulations comprising a bio-derived ester component The present invention is generally directed to the present invention provides for multi-grade engine oil formulations comprising a diester component, wherein the diester component comprises vicinal diester species, and wherein at least a portion of said diester component is bio-derived. Many such formulations of the present invention are expected to favorably compete with similar, existing formulations comprising synthetic esters, but such formulations are generally expected to meet or exceed such existing formulations in a number of areas including, but not limited to, economics, biodegradability, and/or toxicity.
US08586511B2	Scale inhibiting well treatment This invention provides a method for inhibiting scale formation within a hydrocarbon producing system, said method comprising contacting said system with a copolymer formed from a diallyl ammonium salt and at least one other monomer.
US08586508B2	Polysaccharide based cement additives A composition comprising a carboxylated, sulfonated polysaccharide and a wellbore servicing fluid. A wellbore servicing composition comprising a hydraulic cement and a carboxylated, sulfonated polysaccharide. A wellbore servicing composition comprising a polysaccharide having carboxylate and sulfonate groups.
US08586507B2	Oil based drilling fluids with enhanced stability at high temperatures Ester based drilling fluids with enhanced stability at high temperatures for drilling, running casing in, and/or cementing a borehole in a subterranean formation. The drilling fluids comprise a monomeric or polymeric carbodiimide hydrolysis inhibitor.
US08586503B2	Herbicidal compositions Herbicide combinations comprising an effective amount of components (A) and (B), wherecomponent (A) is/are one or more herbicides of the formula (I) or salts thereof, in which R1 is H or a group of the formula CZ1Z2Z3, where Z1, Z2 and Z3 are as defined in claim 1, R2 and R3 are each H, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl having in each case up to 4 carbon atoms or acyl, R4 is H, (C1-C6)-alkyl or (C1-C6)-alkoxy; R5, R6, R7 and R8 are each H, (C1-C4)-alkyl, (C1-C3)-haloalkyl, halogen, (C1-C3)-alkoxy, (C1-C3)-haloalkoxy or cyano; A is CH2 or O or a direct bond, and the component (B) is one or more herbicides from the group of compounds consisting of (B1) thiencarbazone, tembotrione, SYN-523, pyroxsulam, penoxsulam, SYN-449, (B2) pyrasulfotole, trifloxysulfuron, saflufenacil, aminopyralid, ethofumesate, aminocyclopyrachlor and (B3) pyroxasulfone (KIH-485) are suitable for controlling harmful plants or for regulating the growth of plants.
US08586500B2	Hydroconversion multi-metallic catalyst and method for making thereof In a process for forming a bulk hydroprocessing catalyst by sulfiding a catalyst precursor made in a co-precipitation reaction, up to 60% of the metal precursor feeds do not react to form catalyst precursor and end up in the supernatant. In the present disclosure, the metals can be recovered via any of chemical precipitation, ion exchange, electro-coagulation, and combinations thereof to generate an effluent stream containing less than 50 mole % of metal ions in at least one of the metal residuals, and for at least one of the metal residuals is recovered as a metal precursor feed, which can be recycled for use in the co-precipitation reaction. An effluent stream from the process to waste treatment contains less than 50 ppm metal ions.
US08586498B2	Homogeneous asymmetric hydrogenation catalyst Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity.
US08586497B2	Polymerization catalysts, methods of making, methods of using, and polyolefin products made therefrom Olefin polymerization catalyst systems including a high molecular weight catalyst compound and a low molecular weight catalyst compound, and methods of making same are provided. High molecular weight catalysts include metallocene catalysts and low molecular weight catalysts include non-metallocene compounds including biphenyl phenol compounds. Generally catalyst systems may include less than about 5.0 mol % of the high molecular weight catalyst compound relative to said low molecular weight catalyst. Methods for olefin polymerization including the aforementioned catalyst systems, and polyolefins and products made therefrom.
US08586496B2	Preparation of molecular sieve catalysts and their use in the production of alkylaromatic hydrocarbons A method is described for preparing a molecular sieve-containing catalyst for use in a catalytic process conducted in a stirred tank reactor. The method comprises providing a mixture comprising a molecular sieve crystal and forming the mixture into catalyst particles having an average cross-sectional dimension of between about 0.01 mm and about 3.0 mm. The mixture may include a binder and the catalyst particles are then calcined to remove water therefrom and, after calcination and prior to loading the catalyst particles into a reactor for conducting the catalytic process, the catalyst particles are coated with a paraffin inert to the conditions employed in the catalytic process.
US08586494B2	Melted oxide grains including Al, Ti, Mg, and Zr, and ceramic materials comprising such grains The invention relates to a mixture of fused grains having the following chemical composition, in weight percentages on the basis of the oxides: less than 55% of Al2O3; more than 35% and less than 80% of TiO2; more than 1% and less than 20% of MgO; more than 0.7% and less than 20% of ZrO2; and less than 20% of SiO2, said fused grains also corresponding to the following composition, in molar percentages, on the basis of the single oxides Al2O3, TiO2, MgO, ZrO2: 90<2a+3m<110, 100+a<3t<210−a with a+t+m+zr=100, in which: a is the molar percentage of Al2O3; t is the molar percentage of TiO2; m is the molar percentage of MgO; and zr is the molar percentage of ZrO2.The invention also relates to a ceramic product obtained from such fused grains.
US08586492B2	Crack and scratch resistant glass and enclosures made therefrom A glass and an enclosure, including windows, cover plates, and substrates for mobile electronic devices comprising the glass. The glass has a crack initiation threshold that is sufficient to withstand direct impact, has a retained strength following abrasion that is greater than soda lime and alkali aluminosilicate glasses, and is resistant to damage when scratched. The enclosure includes cover plates, windows, screens, and casings for mobile electronic devices and information terminal devices.
US08586490B2	Web materials having both plastic and elastic properties An extruded web is disclosed. The extruded web can be either a nonwoven material of a films. The web comprises a plasto-elastic material where the plasto-elastic material is a combination of a first polyolefin and a second polyolefin (either a polymeric blends or a polymeric mixture). The claimed combination of polyolefins results in a material that has substantially plastic properties when a sample taken from said web is subjected to an initial strain cycle (such that the web is provided with a set of at least 30% by an initial strain cycle) and substantially elastic properties when a sample taken from the web is subjected to at least a second strain cycle.
US08586489B2	Woven fabric A woven fabric is provided that incorporates multiple systems of fibers into a unitary fabric and presents the fibers of only one of the warp systems on a first surface of the fabric. The fabric structure comprises first, second, and third warp systems that are interlaced with weft fibers such that, of the three warp systems, the first surface of the fabric comprises only the first warp system and thus “hides” the second and third warp systems, which are not interwoven with the fibers of the first warp system. In this way, the effect of the appearance of the second and third warp systems on the overall appearance of the fabric is reduced. The three warp systems may include fibers made of different materials to provide different characteristics to each layer of the fabric, or the warp systems may include fibers made of the same material.
US08586488B2	Configuring radiation sources to simultaneously irradiate a substrate A computer program product and system for configuring J electromagnetic radiation sources (J≧2) to simultaneously irradiate a substrate. Each source has a different function of wavelength and angular distribution of emitted radiation. The substrate includes a base layer and I stacks (I≧2) thereon. Pj denotes a same source-specific normally incident energy flux on each stack from source j. For simultaneous exposure of the I stacks to radiation from the J sources, Pj is computed such that an error E being a function of \|W1−S1\|, \|W2−S2\|, \|WI−SI\| is about minimized with respect to Pj (j=1, . . . , J). Wi and Si respectively denote an actual and target energy flux transmitted into the substrate via stack i (i=1, . . . , I). The stacks are exposed to the radiation from the sources characterized by the computed Pj (j=1, . . . , J).
US08586487B2	Low temperature plasma enhanced chemical vapor deposition of conformal silicon carbon nitride and silicon nitride films Methods and apparatus for forming conformal silicon nitride films at low temperatures on a substrate are provided. The methods of forming a silicon nitride layer include performing a deposition cycle including flowing a processing gas mixture into a processing chamber having a substrate therein, wherein the processing gas mixture comprises precursor gas molecules having labile silicon to nitrogen, silicon to carbon, or nitrogen to carbon bonds, activating the precursor gas at a temperature between about 20° C. to about 480° C. by preferentially breaking labile bonds to provide one or more reaction sites along a precursor gas molecule, forming a precursor material layer on the substrate, wherein the activated precursor gas molecules bond with a surface on the substrate at the one or more reaction sites, and performing a plasma treatment process on the precursor material layer to form a conformal silicon nitride layer.
US08586486B2	Method for forming semiconductor device A method of patterning a material layer of a semiconductor device is disclosed, the method including treating a material layer above a semiconductor substrate with plasma oxygen; depositing a layer of photoresist over a first surface of the material layer after the treating of the material layer; patterning the layer of photoresist, thereby forming a patterned photoresist, exposing portions of the material layer; etching the exposed portions of at least the material layer to form at least one contact via in the material layer extending to a source or drain region of a device at a surface of the substrate; and removing the patterned photoresist from the first surface of the material layer.
US08586474B2	Method to form a via A method for forming a via, comprising (a) providing a structure comprising a mask (210) disposed on a semiconductor substrate (203), wherein the structure has an opening (215) defined therein which extends through the mask and into the substrate, and wherein the mask comprises a first electrically conductive layer; (b) depositing a second electrically conductive layer (219) such that the second conductive layer is in electrical contact with the first conductive layer, the second conductive layer having a first portion which extends over the surfaces of the opening and a second portion which extends over a portion of the mask adjacent to the opening; (c) removing the second portion of the second conductive layer; and (d) depositing a first metal (221) over the first portion of the second conductive layer.
US08586471B2	Seed layers for metallic interconnects and products A method is disclosed for depositing multiple seed layers for metallic interconnects over a substrate, the substrate includes a patterned insulating layer which comprises an opening surrounded by a field, said opening has sidewalls and top corners, and the method including: depositing a continuous seed layer over the sidewalls, using a first set of deposition parameters; and depositing another seed layer over the substrate, including inside the opening and over a portion of said field, using a second set of deposition parameters, wherein: the second set of deposition parameters includes one deposition parameter which is different from any parameters in the first set, or whose value is different in the first and second sets; the continuous seed layer has a thickness in a range from about 20 Å to not more than 250 Å over the field; and the combined seed layers leave sufficient room for electroplating inside the opening.
US08586469B2	Metal layer end-cut flow A method of patterning a metal layer is disclosed. The method includes providing a substrate and forming a material layer over the substrate. The method includes forming a second material layer over the first material layer. The method includes performing a first patterning process to the second material layer to form a trench in the second material layer. The first patterning process defines a width size of the trench, the width size being measured in a first direction. The method includes performing a second patterning process to the trench to transform the trench. The second patterning process defines a length size of the transformed trench. The length size is measured in a second direction different from the first direction. The method also includes filling the transformed trench with a conductive material.
US08586467B2	Method of mounting electronic component and mounting substrate In flip chip attach of electronic components, underfill is filled between the component and the substrate to alleviate, for example, thermal stress. In electronic component mounting using copper pillars conducted so far, filler contained in the underfill may cause separation in the process of heating and curing the resin. Disclosed is plating the surfaces of the copper pillars with solder. Mobilization of the filler charged in the underfill due to electric fields produced by local cells that are developed upon contact between dissimilar metals, is suppressed, and occurrence of crack at connection portions is obviated. Thus, connection reliability is increased.
US08586465B2	Through silicon via dies and packages A method for preparing a die for packaging is disclosed. A die having first and second major surfaces is provided. Vias and a mask layer are formed on the first major surface of the die. The mask includes mask openings that expose the vias. The mask openings are filled with a conductive material. The method includes reflowing to at least partially fill the vias and contact openings to form via contacts in the vias and surface contacts in the mask openings.
US08586463B2	Method for preparing a layer comprising nickel monosilicide NiSi on a substrate comprising silicon A method for fabricating a layer including nickel monosilicide NiSi on a substrate including silicon. The method includes the steps of incorporating, on a portion of the thickness of the substrate comprising silicon, an element selected from W, Ti, Ta, Mo, Cr and mixtures thereof; depositing, on the substrate, a layer of nickel and a layer of an element selected from Pt, Pd, Rh, and mixtures thereof or a layer comprising both nickel and an element selected from Pt, Pd, Rh, and mixtures thereof; heating to a temperature sufficient for obtaining the formation of a layer comprising nickel silicide optionally in the form of nickel monosilicide NiSi; incorporating fluorine in the layer; and optionally, heating to a sufficient temperature to convert the layer to a layer comprising nickel silicide entirely in the form of nickel monosilicide NiSi.
US08586460B2	Controlling laser annealed junction depth by implant modification Methods of enabling the use of high wavelength lasers to create shallow melt junctions are disclosed. In some embodiments, the substrate may be preamorphized to change its absorption characteristics prior to the implantation of a dopant. In other embodiments, a single implant may serve to amorphize the substrate and provide dopant. Once the substrate is sufficiently amorphized, a laser melt anneal may be performed. Due to the changes in the absorption characteristics of the substrate, longer wavelength lasers may be used for the anneal, thereby reducing cost.
US08586457B1	Method of fabricating high efficiency CIGS solar cells A method for fabricating high efficiency CIGS solar cells including the deposition of Ga concentrations (Ga/(Ga+In)=0.25−0.66) from sputtering targets containing Ga concentrations between about 25 atomic % and about 66 atomic %. Further, the method includes a high temperature selenization process integrated with a high temperature anneal process that results in high efficiency.
US08586456B2	Use of CL2 and/or HCL during silicon epitaxial film formation In a first aspect, a method of forming an epitaxial film on a substrate is provided. The method includes (a) providing a substrate; (b) exposing the substrate to a silicon source and a carbon source so as to form a carbon-containing silicon epitaxial film; (c) encapsulating the carbon-containing silicon epitaxial film with an encapsulating film; and (d) exposing the substrate to Cl2 so as to etch the encapsulating film. Numerous other aspects are provided.
US08586455B1	Preventing shorting of adjacent devices Embodiments of the present invention provide a method of preventing electrical shorting of adjacent semiconductor devices. The method includes forming a plurality of fins of a plurality of field-effect-transistors on a substrate; forming at least one barrier structure between a first and a second fin of the plurality of fins; and growing an epitaxial film from the plurality of fins, the epitaxial film extending horizontally from sidewalls of at least the first and second fins and reaching the barrier structure situating between the first and second fins.
US08586453B2	Methods for fabricating thin film pattern and array substrate A method for fabricating a thin film pattern and a method for fabricating an array substrate are provided. The method for fabricating a thin film pattern comprises: forming a first film and a second film sequentially; applying a layer of photoresist on the second film; forming a photoresist pattern comprising a totally left region, a partially left region and a totally removed region; performing a first wet etching on the second film in the totally removed region; performing a first dry etching on the first film in the totally removed region to form a first pattern, and etching the photoresist layer to remove the photoresist in the partially left region to expose the second film in the partially left region; performing a second wet etching on the second film in the partially left region; performing a second dry etching to form a second pattern; and removing the residual photoresist.
US08586452B2	Methods for forming semiconductor device structures The benefits of strained semiconductors are combined with silicon-on-insulator approaches to substrate and device fabrication.
US08586451B2	Flexible electronic device and method for the fabrication of same A semiconductor device may have a thickness, such that the semiconductor devices are not flexible, and may be bonded and electrically coupled on a flexible substrate. After this bonding, the semiconductor device may be thinned so as to be rendered flexible.
US08586447B2	Semiconductor device and manufacturing method of the same In a semiconductor device, capacitance between copper interconnections is decreased and the insulation breakdown is improved simultaneously, and a countermeasure is taken for misalignment via by a manufacturing method including the steps of forming an interconnection containing copper as a main ingredient in an insulative film above a substrate, forming insulative films and a barrier insulative film for a reservoir pattern, forming an insulative film capable of suppressing or preventing copper from diffusing on the upper surface and on the lateral surface of the interconnection and above the insulative film and the insulative film, forming insulative films of low dielectric constant, in which the insulative film is formed such that the deposition rate above the opposing lateral surfaces of the interconnections is larger than the deposition rate therebelow to form an air gap between the adjacent interconnections and, finally, planarizing the insulative film by interlayer CMP.
US08586446B2	Manufacturing method of semiconductor device According to one embodiment, a silicon film, in which an impurity density of a center portion is higher than that of an upper portion and a lower portion, is formed above a base layer, a mask pattern is formed above the silicon film, a recess is formed in the silicon film by selectively etching the silicon film through the mask pattern, a silicon oxide film is formed on a surface of the recess by an oxidation process of the silicon film, and the silicon film under the recess is etched through the mask pattern after the oxidation process.
US08586443B2	Method of fabricating phase change memory device capable of reducing disturbance A phase change memory device capable of reducing disturbances between adjacent PRAM memory cells and a fabrication method are presented. The phase change memory device includes word lines, heating electrodes, an interlayer insulating layer, and a phase change lines. The word lines are formed on a semiconductor substrate and extend in parallel with a constant space. The heating electrodes are electrically connected to the plurality of word lines. The interlayer insulating layer insulates the heating electrodes. The phase change lines extend in a direction orthogonal to the word line and are electrically connected to the heating electrodes. Curves are formed on a surface of the interlayer insulating layer between the word lines such that the effective length of the phase change layer between adjacent heating electrodes is larger than the physical distance between the adjacent heating electrodes.
US08586441B1	Germanium lateral bipolar junction transistor A germanium lateral bipolar junction transistor (BJT) is formed employing a germanium-on-insulator (GOI) substrate. A silicon passivation layer is deposited on the top surface of a germanium layer in the GOI substrate. Shallow trench isolation structures, an extrinsic base region structure, and a base spacer are subsequently formed. A germanium emitter region, a germanium base region, and a germanium collector region are formed within the germanium layer by ion implantation. A silicon emitter region, a silicon base region, and a silicon collector region are formed in the silicon passivation layer. After optional formation of an emitter contact region and a collector contact region, metal semiconductor alloy regions can be formed. A wide gap contact for minority carriers is provided between the silicon base region and the germanium base region and between the silicon emitter region and the germanium emitter region.
US08586440B2	Methods for fabricating integrated circuits using non-oxidizing resist removal Methods are provided for fabricating integrated circuits using non-oxidizing resist removal. In accordance with one embodiment the method includes forming a gate electrode structure overlying a semiconductor substrate and applying and patterning a layer of resist to expose a portion of the semiconductor substrate adjacent the gate electrode structure. Conductivity determining ions are implanted into the semiconductor substrate using the gate electrode structure and the layer of resist as an implant mask. The layer of resist is removed in a non-oxidizing ambient and the implanted conductivity determining ions are activated by thermal annealing.
US08586437B2	Semiconductor device and method of manufacturing the semiconductor device A method of manufacturing a semiconductor device includes forming a first region including a FinFET (Fin Field Effect Transistor), forming a second region including a PlanarFET (Planar Field Effect Transistor), forming first extension regions in the plurality of fins in the first region, forming second extension regions in the second region using the second gate electrode as a mask, forming first side walls and second side walls on side surfaces of the first gate electrode and on side surfaces of the second gate electrode, respectively, and forming a source and a drain of the FinFET in the first region using the first gate electrode and first side walls as masks and forming a source and a drain of the PlanarFET in the second region by an ion implantation method using the second gate electrode and second side walls as masks, at the same time.
US08586434B1	Method of manufacturing semiconductor device A method of manufacturing a semiconductor device may include forming a first n− type epitaxial layer by performing a first epitaxial growth on a first surface of an n+ type silicon carbide substrate, forming a photosensitive layer pattern on the first n− type epitaxial layer, etching the first n− type epitaxial layer by using the photosensitive layer pattern as a mask to form a first trench, forming a buffer layer on the first n− type epitaxial layer after the photosensitive layer pattern may be removed, etching the buffer layer to form a trench passivation layer in the first trench, forming an n− type epitaxial layer by performing a second epitaxial growth on the first n− type epitaxial layer, and forming a p type epitaxial layer by performing a third epitaxial growth on the n− type epitaxial layer other than the portion on which the trench passivation layer may be formed.
US08586432B2	Method for manufacturing vertical-channel tunneling transistor The present invention belongs to the technical field of semiconductors and specifically relates to a method for manufacturing a vertical-channel tunneling transistor. In the present invention, the surrounding gate gate structure improves the control capacity of the gate and the source of narrow band gap material can enhance the device driving current. The method for manufacturing a vertical-channel tunneling transistor put forward by the present invention capable of controlling the channel length precisely features simple process, easy control and reduction of production cost.
US08586427B2	Thin film transistors and methods of manufacturing thin film transistors A thin film transistor includes a layer structure having a gate electrode, a gate insulation layer and a channel layer. A source line may contact the channel layer, and may extend along a direction crossing over the gate electrode. The source line may partially overlap the gate electrode so that both sides of the source line overlapping the gate electrode may be entirely positioned between both sides of the gate electrode. A drain line may make contact with the channel layer and may be spaced apart from the source line by a channel length. The drain line may have a structure symmetrical to that of the source line. Overlap areas among the gate electrode, the source line and the drain line may be reduced, so that the thin film transistor may ensure a high cut-off frequency.
US08586418B2	Method for the production of an electronic component and electronic component produced according to this method The invention relates to an electronic component having a circuit integrated on a semiconductor substrate, and a heat-conducting connection of the substrate by soldering using a carrier serving as a heat sink, wherein the invention proposes depositing a first, thicker Au layer (23) in the conventional back-side metallization of the substrate, thereafter a barrier coating (24), and, as the last layer, a thinner, second Au layer (25), wherein the material of the barrier coating is selected such that the barrier coating prevents the penetration by means of a diffusion barrier of Sn or AuSn from a liquid Au—Sn phase in the region of the second Au layer into the first Au layer (23) during the soldering process. The layer sequence of the back-side metallization is also deposited in the pass-through openings of the substrate, wherein the surface of the second Au layer comprises a reduced coatablity for the solder material due to the material diffused out of the barrier coating.
US08586416B2	Method of manufacturing semiconductor device Provided is a technology of suppressing, in forming an initial ball by using an easily oxidizable conductive wire and pressing the initial ball onto a pad to form a press-bonded ball, an initial ball from having a shape defect, thereby reducing damage to the pad. To achieve this, a ball formation unit is equipped with a gas outlet portion for discharging an antioxidant gas and a discharging path through this gas outlet portion is placed in a direction different from a direction of introducing the antioxidant gas into a ball formation portion. Such a structure widens a region for discharging the antioxidant gas, making it possible to prevent a gas flow supplied from the side of one side surface of the ball formation portion from being reflected by the other side surface facing with the one side surface and thereby forming a turbulent flow.
US08586415B2	Dicing/die-bonding film, method of fixing chipped work and semiconductor device A dicing/die-bonding film including a pressure-sensitive adhesive layer (2) on a supporting base material (1) and a die-bonding adhesive layer (3) on the pressure-sensitive adhesive layer (2), wherein a releasability in an interface between the pressure-sensitive adhesive layer (2) and the die-bonding adhesive layer (3) is different between an interface (A) corresponding to a work-attaching region (3a) in the die-bonding adhesive layer (3) and an interface (B) corresponding to a part or a whole of the other region (3b), and the releasability of the interface (A) is higher than the releasability of the interface (B). The dicing/die-bonding film is excellent in balance between retention in dicing a work and releasability in releasing its diced chipped work together with the die-bonding adhesive layer.
US08586408B2	Contact and method of formation A system and method for forming contacts is provided. An embodiment comprises forming the contacts on a substrate and then coining the contacts by physically shaping them using, e.g., a molding chamber. The physical shaping of the contacts may be performed using a patterned portion of the molding chamber or else by placing a patterned stencil around the contacts prior before a force is applied to physically reshape the contacts. The contacts may be reshaped into a cylindrical, oval, cuboid, or rectangular shape, for example.
US08586407B2	Method for depackaging prepackaged integrated circuit die and a product from the method A method for providing a known good integrated circuit die having enhanced planarity from a prepackaged integrated circuit die having a surface warpage such as in a ball grid array (BGA) package is provided. A partially-depackaged integrated circuit package is affixed to a substrate with a spacer element there between such that the active surface of the die within the partially depackaged integrated circuit die is “bowed” slightly upwardly to define a convex surface. The exposed encapsulant on the now-convex surface of the mounted, partially-depackaged integrated circuit package is then lapped or ground away to a predetermined depth so that an integrated circuit die is provided having an enhanced planarity and surface uniformity.
US08586405B2	Semiconductor device manufacturing method A method of manufacturing a semiconductor device and a semiconductor device made by the method is disclosed. The method comprises forming a buried N+ layer in an upper portion of a P-type substrate; performing ion implantation on the buried N+ layer; annealing the buried N+ layer; forming an epitaxial semiconductor layer on the buried N+ layer through epitaxial deposition, wherein, an upper portion of said epitaxial semiconductor layer and a portion underlying said P+ region of said epitaxial semiconductor layer are doped to form a P+ region and an N− region, respectively. Increasing the ion implant dosage of the BNL layer, adjusting the method of annealing the BNL layer to increase the width of the BNL layer, or increasing the thickness of the EPI layer, reduces the vertical BJT current gain and suppressed the substrate leakage current.
US08586404B2	Method for reducing contact resistance of CMOS image sensor This description relates to a method for reducing CMOS Image Sensor (CIS) contact resistance, the CIS having a pixel array and a periphery. The method includes performing Physical Vapor Deposition (PVD) at a pixel contact hole area, annealing for silicide formation at the pixel contact hole area and performing contact filling. This description also relates to a method for reducing CMOS Image Sensor (CIS) contact resistance, the CIS having a pixel array and a periphery. The method includes implanting N+ or P+ for pixel contact plugs at a pixel contact hole area, performing Physical Vapor Deposition (PVD) at pixel contact hole area, annealing for silicide formation at the pixel contact hole area, performing contact filling and depositing a first metal film layer, wherein the first metal film layer links contact holes for a source, a drain, or a poly gate of a CMOS device.
US08586401B2	Gas injection device and solar cell manufacturing method using the same A solar cell manufacturing method includes forming a first electrode on a substrate, forming a mixed metal layer on the first electrode, forming a light absorbing layer by injecting hydrogen selenide on the entire surface of the mixed metal layer using a gas injection device, and forming a second electrode on the light absorbing layer. Further, the gas injection device includes a gas pipeline, an inner gas pipe positioned in the gas pipeline and having an opening, and a plurality of injection nozzles disposed below the gas pipeline.
US08586398B2	Sodium-incorporation in solar cell substrates and contacts Provided herein are methods of incorporating additives into thin-film solar cell substrates and back contacts. In certain embodiments, sodium is incorporated into a substrate or a back contact of a thin-film photovoltaic stack where it can diffuse into a CIGS or other absorber layer to improve efficiency and/or growth of the layer. The methods involve laser treating the substrate or back contact in the presence of a sodium (or sodium-containing) solid or vapor to thereby incorporate sodium into the surface of the substrate or back contact. In certain embodiments, the surface is simultaneously smoothed.
US08586394B2	Method for producing a subminiature “micro-chip” oxygen sensor for control of internal combustion engines or other combustion processes, oxygen sensor and an exhaust safety switch A method of making a sub-miniature “micro-chip” oxygen sensor is provided where multiple sensor elements are applied to a dielectric ceramic substrate consisting of a heater pattern, followed by a dielectric layer. Intermeshing electrodes are then applied either over the heater pattern/dielectric layers or on the opposite side of the substrate. The space between the intermeshing electrodes is filled with an n-type or p-type high temperature semiconductor which is covered by a porous protection layer. After singulation (dicing), the sensor element is assembled having conductors applied to the contact pads on the element and is packaged in an assembly for introduction to the exhaust stream of a combustion process. A large step-wise change in the resistance of the element takes place as a result of changes in oxygen content in the exhaust whereby one can determine if the exhaust is rich or lean for use in an engine management or combustion management systems for emissions control. A circuit is proposed to convert the change in resistance to a voltage signal to be used for control algorithms in engine or combustion control. Utilizing multiple units of the device for individual cylinder control of multi-cylinder engines is described. A method of using one embodiment of the invention for use as a safety switch is also revealed.
US08586392B2	Display device and manufacturing method thereof A manufacturing method of a display device including a gate electrode film, a first electrode film, a second electrode film, and a conductive film connected to the first electrode film and formed of a conductive layer including a first conductive layer and a second conductive layer formed overlapping the first conductive layer. The method includes the steps of forming the first electrode film and the second electrode film, forming the conductive layer such that the conductive layer is connected to the first electrode film and the second electrode film, and forming the conductive film by removing regions other than predetermined regions of the conductive layer, wherein the conductive layer forming step includes the steps of forming the first conductive layer on the respective upper surfaces of the first electrode film and the second electrode film and forming the second conductive layer on the upper surface of the first conductive layer.
US08586391B2	Method of manufacturing light-emitting device A method of manufacturing a light-emitting device includes providing a plate-shaped substrate, forming a lattice frame on a light-emitting element mounting surface of the plate-shaped substrate, mounting a light-emitting device in an opening of the lattice frame on the light-emitting element mounting surface, sealing the light-emitting element by supplying a sealing material into the opening of the lattice frame, and cutting the lattice frame and the plate-shaped substrate so as to split the lattice flame to obtain a plurality of light-emitting devices with a sidewall.
US08586390B2	Method for manufacturing semiconductor device According to one embodiment, a method for manufacturing a semiconductor device is disclosed. The device includes a magnetoresistance effect element using magnetic material containing at least one of cobalt, iron, and nickel. Forming the element includes forming a stacked body above a semiconductor substrate. The stacked body includes layers. The layers includes the magnetic material. Forming the element further includes processing the stacked body in a vacuum atmosphere by plasma etching using a first gas containing chlorine. Forming the element further includes subjecting the stacked body to a gas treatment using a second gas containing an amino group while holding the stacked body in the vacuum atmosphere.
US08586387B2	Methods of triggering activation of encapsulated signal-generating substances and apparatus utilising activated signal-generating substances A method of performing a bioassay comprising activating capsules containing a signal precursor that is hydrolysable from a latent form in which substantially no signal is generated to a form in which it is able to generate a detectable signal, said activating comprising treating said capsules with heat and with an acid or a base catalysing solution, the combination of said heat and the pH of the catalysing solution being such as to hydrolyse said precursor to the form in which it is able to generate a detectable signal.
US08586383B2	Device and method for detection of harmful substances The invention relates to a device (10) for detection of harmful substances with a measurement unit (28) for measuring at least one harmful substance and an evaluation unit (30) for determining the concentration of the at least one harmful substance. The invention also relates to a method for detecting harmful substances in a gas mixture. It is hereby provided that the gas mixture is tested for a gaseous harmful substance or simultaneously for several gaseous harmful substances, wherein the gaseous harmful substance or the gaseous harmful substances is/are measured with different sensor means, and the gaseous harmful substances are optionally chemically modified such that a measurement is performed with the existing sensor means.
US08586381B2	Mobile intra-operative microscopic diagnosis laboratory A mobile intra-operative microscopic diagnosis laboratory capable of analyzing fresh tissue specimens and providing intra-operative consultation within 20 minutes is described. The mobile laboratory is preferably a van and contains a cryostat for freezing the fresh tissue specimens and a means for cutting the specimens. In addition, it also contains the means for reading the slides to make microscopic diagnosis and a means for handling for fresh tissue and a means for indicating various locations in the specimen, preferably by inking them. It preferably contains a stainer for staining the samples and an intercom for communicating the microscopic diagnosis back to the operating room.
US08586380B2	Monitoring treatment of head and neck cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or colorectal cancer patient has likely developed a non-responsiveness to treatment with a drug targeting an epidermal growth factor receptor pathway. As the methods of this disclosure require only simple blood samples, the methods enable a fast and non-intrusive way of measuring when drugs targeting the EGFR pathway cease to be effective in certain patients. This discovery represents the first known example of true personalized selection of these types of cancer patients for treatment using these classes of drugs not only initially, but during the course of treatment.
US08586375B2	Rapid diagnostic device, assay and multifunctional buffer A rapid diagnostic device, assay and multifunctional buffer reagent are provided for the detection of a target analyte in a fluid test sample. The 2-step assay utilizes a dual component flow-through device comprising a test unit and a dried indicator reagent delivery unit for receiving the fluid sample and multifunctional buffer, respectively. The test unit comprises a reaction zone containing immobilized capture reagent that can bind to the target analyte, an absorbent zone supporting the reaction zone, and optionally, a blood separation zone in lateral fluid communication with the reaction zone. The delivery unit comprises a label zone permeated with a dried indicator reagent which can be placed in transient fluid communication with the reaction zone of the test unit during the assay procedure. The rapid diagnostic assay system reduces the number of assay reagents, method steps and time required for performance compared to other conventional assays.
US08586373B2	System and method for determining the concentration of an analyte in a sample fluid The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 3.0 seconds or less, and/or having a clinically low Total System Error.
US08586371B2	Optical sensors including surface modified phase-change materials for detection of chemical, biological and explosive compounds A sensor device includes an optical limiting structure including a metal layer with at least one metal particle having a size no greater than about 1500 nanometers, and a phase-change material layer disposed adjacent at least a portion of the metal layer, the phase-change material layer including a phase-change material, and a dendritic-metal layer disposed over at least a portion of the phase-change material layer of the optical limiting structure, the dendritic-metal layer including an organic compound including branching chain amino acid groups attached to a metal structure. The optical limiting structure is configured to transition from a first optical state to a second optical state when the phase-change material is heated above a critical temperature, with transmittance of light at a predetermined wavelength through the optical limiting structure being lower at the second optical state of the optical limiting structure in relation to the first optical state of the optical limiting structure.
US08586367B2	Methods for analyzing polar metabolites of the energy metabolism The present invention is concerned with the analysis of polar metabolites and provides methods for analyzing polar metabolites including extracting a biological sample with a extraction buffer containing a phase separator and a volatile neutral ammonium salt under conditions which allow for immediate disruption of cells in the biological sample, separating the polar metabolites in the extract by chromatography, and analyzing the separated polar metabolites. Moreover, a method for quenching a biological sample containing cellular material is contemplated.
US08586357B2	Markers of definitive endoderm Disclosed herein are reagent-cell complexes comprising one or more definitive endoderm cells. Also described herein are compositions for detecting definitive endoderm. Method of enriching, isolating and/or purifying definitive endoderm cells are also disclosed.
US08586356B2	Gal α1-3gal-containing N-glycans in glycoprotein products derived from CHO cells The present invention provides methods of evaluating CHO cells.
US08586349B2	Moving droplet diagnostic assay The present invention concerns a method for the detection of an analyte in a droplet of fluid comprising the steps of providing a solid phase with a hydrophobic surface comprising at least one capture zone on which at least one binding agent with affinity for the analyte is immobilized, applying said droplet to the surface of said solid phase, applying a force that makes the droplet travel along the surface of said solid phase along a predetermined path thereby allowing the droplet to repeatedly contact said binding agent on the capture zone, applying conditions wherein said analyte is allowed to bind to said binding agent and detecting a complex of analyte and binding reagent at the position of the capture zone. The effect of a moving droplet is that the reactants in the droplet are well mixed which eliminates the risk of diffusion limitation. Such advantageous mixing is not obtained with conventional assays in which the surface is continuously exposed to the liquid. The use of a droplet eliminates the need for external mixing and also circumvents the need to dilute the sample in order to obtain sufficient volume to wet a large surface area.
US08586346B2	Polypeptides having cellobiohydrolase activity and polynucleotides encoding same The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US08586340B2	Selective posttranslational modification of phage-displayed polypeptides The invention relates to posttranslational modification of phage-displayed polypeptides. These displayed polypeptides comprise at least one unnatural amino acid, e.g., an aryl-azide amino acid such as p-azido-L-phenylalanine, or an alkynyl-amino acid such as para-propargyloxyphenylalanine, which are incorporated into the phage-displayed fusion polypeptide at a selected position by using an in vivo orthogonal translation system comprising a suitable orthogonal aminoacyl-tRNA synthetase and a suitable orthogonal tRNA species. These unnatural amino acids advantageously provide targets for posttranslational modifications such as azide-alkyne [3+2] cycloaddition reactions and Staudinger modifications.
US08586339B2	Facilitated process for purification of proteins A two-stage heat treatment process is provided to improve the processability of recombinant microbial biomass comprising an enzyme having perhydrolytic activity. More specifically, a process is provided to treat the recombinant microbial biomass comprising a Thermotoga sp. acetyl xylan esterase having perhydrolytic activity such that microfiltration may be used to partially-purify and/or concentrate protein preparations. The acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.
US08586338B2	Ligand functionalized substrates Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
US08586337B2	Systems and methods for achieving partial nitrification in a biological nitrogen removal reactor Methods of controlling a nitrification reaction in a biological nitrogen removal reactor to favor partial nitrification of ammonia to nitrite instead of complete oxidation of ammonia to nitrate are disclosed. In some embodiments, the methods include the following: maintaining a pH in the reactor within a range that promotes growth of ammonia oxidizing bacteria; maintaining a concentration of dissolved oxygen in the reactor within a range that limits the ammonia oxidizing bacteria from completing nitrification; selecting an operational solids retention time within a range suitable for maintaining increasing concentrations of the ammonia oxidizing bacteria in the reactor while reducing concentrations of nitrite oxidizing bacteria in the reactor; and increasing a concentration of free ammonia in the reactor thereby inhibiting growth of the nitrite oxidizing bacteria in the reactor.
US08586336B2	Nucleic acid molecule encoding xylose isomerase and xylose isomerase encoded by the nucleic acid molecule A novel xylose isomerase nucleotide sequence obtained from a bovine rumen fluid metagenomic library and also provides the amino acid sequence encoded by the nucleotide sequence, and a vector and a transformant containing the nucleotide sequence. When the xylose isomerase is expressed, a host cell is endowed with the capability of converting xylose into xylulose, and the xylulose is further metabolized by the host cell. Therefore, the host cell can take the xylose as a carbon source for growth. The xylose isomerase from a new source is expressed with high activity in Saccharomyces cerevisiae and is a mesophilic enzyme with optimal temperature of 60° C.
US08586333B2	Polypeptides having isoamylase activity and methods of use The present invention relates to isolated polypeptides having isoamylase activity derived from Dyella japonica and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. The invention also relates to the use of said polypeptide having isoamylase activity for producing glucose syrup, fructose syrup, maltose syrup or maltitol.
US08586331B2	Process for the production of the Actinobacillus pleuropneumoniae toxin ApxI employing a culture medium comprising calcium-borogluconate complex The present invention pertains to a method to produce RTX-toxin Apxl by culturing Actinobacillus pleuropneumoniae bacteria in a liquid culturing medium that supports growth of the bacteria, to which medium a calcium salt is added to form calcium ions in the medium, wherein the culturing medium contains borogluconate to form a calcium borogluconate complex in the medium.
US08586329B2	Neurotoxins exhibiting shortened biological activity The present invention relates to the pharmaceutical field. Specifically, it contemplates a polynucleotide encoding a neurotoxin polypeptide exhibiting a reduced duration of the biological effect in a subject, wherein the polypeptide comprises at least one degradation signal in the light chain of the neurotoxin polypeptide as well as vectors and host cells comprising the polynucleotide, polypeptides encoded thereby and antibodies specifically binding to the polypeptides. Moreover, the invention relates to medicaments comprising the polynucleotides and polypeptides, as well as specific therapeutic applications thereof. Furthermore, the present invention contemplates methods for the manufacture of the polypeptides and medicaments.
US08586328B2	Method for producing sclareol The present invention provides a method of producing sclareol, said method comprising contacting a particular polypeptide having a sclareol synthase activity with labdenediol diphosphate (LPP). In particular, said method may be carried out in vitro or in vivo to produce sclareol, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of the polypeptide used in the method. A nucleic acid derived from Salvia sclarea and encoding the polypeptide of the invention, an expression vector containing said nucleic acid, as well as a non-human host organism or a cell transformed to harbor the same nucleic acid, are also part of the present invention.
US08586324B2	Method and apparatus to create autologous clotting serum A method for preparing and isolating clotting serum. The method includes adding reagent and a clotting serum source to a reaction chamber of a clotting serum production device that includes an activator. The reagent, clotting serum source and activator are mixed by shaking the serum production device to bring the contents to a foam. The serum production device is placed in either a vacuum or at room temperature for a period of time, and the clotting serum is extracted from the reaction chamber.
US08586323B2	Blood coagulation promoter and blood collection tube comprising a polyoxyalkylene glycerin derivative The present invention provides a blood coagulation promoter capable of exerting both excellent blood coagulation promoting ability and excellent blood clot detaching ability; and a blood collection tube accommodating the blood coagulation promoter.The present invention provides a blood coagulation promoter which includes a hardly water soluble polyoxyalkylene derivative; a partially saponificated polyvinyl alcohol; at least one substance selected from the group consisting of adsorptive inorganic substances and hydrolases capable of hydrolyzing a bond between Arg and an arbitrary amino acid reside and/or a bond between Lys and an arbitrary amino acid residue in a peptide chain; a polyvinylpyrrolidone; and preferably a water-soluble silicone oil, and a blood collection tube in which the blood coagulation promoter is accommodated in a tubular vessel having a bottom.
US08586320B2	Methods for prognosing the recurrence of gastrointestinal and other cancers using the Shc proteins The invention relates to methods for prognosing the recurrence of gastrointestinal and other cancers using tyrosine phosphorylated Shc (PY-Shc) and/or p66-Shc.
US08586314B2	Peptide nucleic acid probes for detection, identification and/or quantitation of Pseudomonas (sensu stricto) Disclosed is a PNA probe that includes a nucleobase sequence suitable for the detection, identification and/or quantitation of Pseudomonas (sensu stricto). In one embodiment, the PNA probe is complementary to a target sequence of 23S rRNA or rDNA from all species of the genus Pseudomonas. The invention has a wide range of important uses including detecting Pseudomonas in a sample of interest.
US08586312B2	Methods of using an array of pooled probes in genetic analysis The invention provides arrays of polynucleotide probes having at least one pooled position. A typical array comprises a support having at least three discrete regions. A first region bears a pool of polynucleotide probes comprising first and second probes. A second region bears the first probe without the second probe and a third region bears the second probe without the first probe. A target nucleic acid having segments complementary to both the first and second probes shows stronger normalized binding to the first region than to the aggregate of binding to the second and third regions due to cooperative binding of pooled probes in the first region. The invention provides methods of using such arrays for e.g., linkage analysis, sequence analysis, and expression monitoring.
US08586311B2	Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing TS and/or ERCC1 expression levels in fixed or fixed and paraffin embedded tissues and prognosticate the probable resistance of a patient's tumor to treatment with 5-FU and oxaliplatin-based therapies by examination of the amount of TS and/or ERCC1 mRNA in a patient's tumor cells and comparing it to a predetermined threshold expression level for those genes. More specifically, the invention provides to oligonucleotide primer pairs ERCC1 and TS and methods comprising their use for detecting levels of ERCC1 and TS mRNA, respectively.
US08586310B2	Method for multiplexed nucleic acid patch polymerase chain reaction The invention encompasses a method for amplifying at least two different nucleic acid sequences. In particular, the method encompasses a multiplexed nucleic acid patch polymerase chain reaction.
US08586306B2	Preservation of cell-free RNA in blood samples A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
US08586300B2	Genetic polymorphisms and infertility Methods of screening for a cause of low sperm motility and/or for mitochondrial impairment in subjects are provided, comprising determining a genotype of the subject with respect to at least one choline metabolism gene and comparing the genotype of the subject with at least one reference choline metabolism genotype associated with low sperm motility and/or impaired mitochondrial function, wherein a similarity between the subject and reference genotypes indicates a cause of low sperm motility and/or impaired mitochondrial function in the subject. In another aspect, methods for treating subjects having low sperm motility and/or impaired mitochondrial function are provided, comprising administering to the subject an effective amount of a choline metabolism supplement composition to at least partially ameliorate the low sperm motility and/or impaired mitochondrial function.
US08586296B2	Method to identify and predict disease progression of human papilloma virus-infected lesions The present invention provides a method for distinguishing benign human papilloma virus (HPV)-infected tissue from HPV-related lesions that have undergone malignant transformation. In one embodiment, the invention comprises a simple histochemical staining method and details a novel process for examining HPV-infected cells by determining susceptibility to enzymatic DNA digestion. Residual virion-associated DNA is seen only in benign HPV-infected lesions, while absence of residual DNA is seen with malignant transformation. In another embodiment, the invention comprises immunohistochemical assay methods for examining HPV-infected cells, utilizing antibodies to HPV L1 proteins. These methods can be used to predict biologic behavior of HPV-infected lesions. The invention can improve current cervical cancer screening programs, and improve clinical management of patients by defining malignant potential of HPV-infected tissue more accurately.
US08586295B2	Method for screening HIV drug sensitivity This present invention provides a method for monitoring ARV resistance, to determine viral fitness, and to forecast possible drug failure. The method provides improved personalized HIV/AIDS care to the patient-physician over existing assays at a reduced cost. This set of assays will utilize the same PCR amplicon of the patient HIV genome, which encompasses all of the drug targeted HIV-1 genes (polPR-RT-IN-envgp120-gp41) and not just PR-RT as with the prior systems. The greatest advantage of this method over previous is the rapid cloning of this amplicon into an HIV-1 genome vector through yeast recombination/gap repair. The vectors can be directly passed from yeast to mammalian cell line which has been specifically engineered to produce replication competent HIV-1 particles and to test susceptibility to all ARVs, i.e. PRIs, NRTIs, NNRTIs, T20, as well as entry and integrase inhibitors in development/clinical trials.
US08586294B2	Detection of protein translocation by beta-galactosidase reporter fragment complementation Methods and compositions are provided for detecting molecular translocations, particularly protein translocations within and between subcellular copartments, using at least two components that exhibit a localization-dependent difference in complementation activity. In particular, alpha-complementing β-galactosidase fragments are provided. These β-galactosidase reporter fragments display significantly enhanced enzymatic activity when one fragment is localized in a membrane. Methods for carrying out no-wash ELISA assays based on the reporter component system are also provided.
US08586291B2	Mutations in the Bcr-Abl tyrosine kinase associated with resistance to ST1-571 The invention described herein relates to novel genes and their encoded proteins, termed Mutants Associated with Resistance to STI-571 (e.g., T315I Bcr-Abl), and to diagnostic and therapeutic methods and compositions useful in the management of various cancers that express MARS. The invention further provides methods for identifying molecules that bind to and/or modulate the functional activity of MARS.
US08586290B2	Patterning process and chemical amplified photoresist composition A lithography method includes forming a photosensitive layer on a substrate, exposing the photosensitive layer, baking the photosensitive layer, and developing the exposed photosensitive layer. The photosensitive layer includes a polymer that turns soluble to a base solution in response to reaction with acid, a plurality of photo-acid generators (PAGs) that decompose to form acid in response to radiation energy, and a plurality of quenchers having boiling points distributed between about 200 C and about 350 C. The quenchers also have molecular weights distributed between 300 Dalton and about 20000 Dalton, and are vertically distributed in the photosensitive layer such that a first concentration C1 at a top portion of the photosensitive layer is greater than a second concentration C2 at a bottom portion of the photosensitive layer.
US08586289B2	Aromatic hydrocarbon resin and composition for forming underlayer film for lithography The aromatic hydrocarbon resin can be used as a coating material and a resist resin for a semiconductor, and has a high carbon concentration and a low oxygen concentration. A composition for forming an underlayer film for lithography that has excellent etching resistance as an underlayer film for a multilayer resist process, an underlayer film formed with the same, and a pattern forming method using the same are disclosed. An aromatic hydrocarbon is reacted with an aromatic aldehyde in the presence of an acidic catalyst, thereby providing an aromatic hydrocarbon resin that has a high carbon concentration of from 90 to 99.9% by mass and a low oxygen concentration of from 0 to 5% by mass. A composition for forming an underlayer film for lithography contains the resin and an organic solvent, an underlayer film is formed with the same, and a pattern forming method uses the same.
US08586288B2	Method of forming resist pattern A method of forming a resist pattern including: forming a resist film on a substrate using a resist composition containing a base component (A) which exhibits increased solubility in an organic solvent under action of acid and an acid generator component which generates acid upon exposure; conducting exposure of the resist film; and patterning the resist film by positive development using a developing solution containing the organic solvent to form a resist pattern,wherein a resin component containing a structural unit derived from an acrylate ester which may have a hydrogen atom bonded to a carbon atom on the α-position substituted with a substituent and contains an acid decomposable group which exhibits increased polarity by action of acid is used as the component (A), anda developing solution that contains a polar organic solvent but contains substantially no alkali components is used as the developing solution.
US08586287B2	Fabrication method of cylindrical gratings A phase mask method to geometrically transform and to optically transfer a standard planar radial grating pattern into a cylindrical photoresist pattern at the circularly cylindrical wall of a given element. The planar radial grating pattern can be written with an integer number of lines having strictly constant period without any stitching problem. The photolithographic transfer is made by an illumination device providing a normal incident beam on the phase mask. The annular radial grating diffracts this normal incident beam, formed by plane waves, into two cylindrical waves of the first diffraction order (T+1 and Tr−1) which impinge on the circularly cylindrical wall and interfere in a photoresist layer deposited on the circularly cylindrical wall to give rise to an interferogram.
US08586285B2	Methods for forming sheeting with a composite image that floats and a master tooling A sheeting and a method of forming a sheeting from a master tool are described where the sheeting has a composite image that floats above or below the sheeting. The method includes providing a first sheeting comprising a first array of microlenses and a photopolymerizable first material layer adjacent to the first array of microlenses. Another step is exposing the first sheeting to a radiation source to form a master tool comprising a plurality of polymerized first structured areas in the first material layer, wherein at least some of the first structured areas include a portion shape in common with at least some of the first structured areas and wherein each first structured area is associated with one of the first array of microlenses. Yet another step is replicating the plurality of first structured areas using a substance that conforms to the plurality of structured areas to form a second material layer having a plurality of replicated structured areas.
US08586283B2	Near-infrared absorbing film compositions A curable liquid formulation containing at least (i) one or more near-infrared absorbing triphenylamine-based dyes, and (ii) one or more casting solvents. The invention is also directed to solid near-infrared absorbing films composed of crosslinked forms of the curable liquid formulation. The invention is also directed to a microelectronic substrate containing a coating of the solid near-infrared absorbing film as well as a method for patterning a photoresist layer coated on a microelectronic substrate in the case where the near-infrared absorbing film is between the microelectronic substrate and a photoresist film.
US08586281B2	Positive resist composition and method of forming resist pattern A positive resist composition including: a base component; and a sensitizer which a polymeric compound having a core portion that includes a hydrocarbon group or a heterocycle of two or more valences and at least one arm portion bonded to the core portion and represented by formula (1), and a polymeric compound having a core portion including a polymer having a molecular weight of 500 to 20,000 and at least one arm portion bonded to the core portion and represented by formula (1); and either the base component includes a resin component that generates acid upon exposure and exhibits increased solubility in an alkali developing solution under action of acid, or the positive resist composition further contains an acid generator component including a compound that generates acid upon exposure: —(X)—Y (1) in which X represents a divalent linking group having an acid dissociable group; and Y represents a polymer chain.
US08586280B2	Composition, process of preparation and method of application and exposure for light imaging paper The present invention provides dual energy imaging compositions, processes for forming dual energy imaging compositions, methods for forming images using dual energy imaging compositions and substrate (e.g., paper web) treated (e.g., coated) on one or both sides with a dual energy imaging composition. Also provided is a particulate comprising a matrix of polymer material and containing one or more image-forming agents and a photo-oxidizing agent useful in making dual energy imaging compositions.
US08586278B2	Electrostatic image developing toner and producing method of the same A method of producing an electrostatic image developing toner comprising toner particles comprising a binder resin containing at least a non-crystalline polyester resin having a crosslinking structure and a crystalline polyester resin, the method comprising the steps of (a-1) preparing a crystalline polyester resin particle aqueous dispersion liquid; (a-2) preparing a polymerizable unsaturated non-crystalline polyester resin aqueous dispersion liquid; (b) preparing crosslinking non-crystalline polyester resin particles by adding a radical polymerization initiator to the aqueous dispersion liquid of particles containing the non-crystalline polyester resin having a polymerizable unsaturated bond; (c) preparing core particles by aggregating at least the particles containing the crystalline polyester resin in an aqueous medium; and (d) preparing a shell layer containing the non-crystalline polyester resin having a crosslinking structure by fusing the particles containing the non-crystalline polyester resin having a crosslinking structure on surfaces of the core particles in an aqueous medium.
US08586276B2	Carrier for electrostatic latent image development, and developer for electrostatic latent image development, method of forming an image, developer cartridge for electrostatic latent image development, process cartridge and image forming apparatus using the same A carrier for developing an electrostatic latent image includes carrier particles, and the carrier particles include magnetic particles and a coating layer coating the surfaces of the magnetic particles. The BET specific surface area of the magnetic particles is 0.1300 m2/g to 0.2500 m2/g, and the difference in BET specific surface areas obtained by subtracting the BET specific surface area of the magnetic particles from the BET specific surface area of the carrier particles is 0.0300 m2/g to 0.400 m2/g.
US08586274B2	Toner for developing electrostatic charge image and process for its production A toner for developing an electrostatic charge image, which satisfies both low temperature fixing property and blocking resistance and which is excellent in the fixed image strength and further excellent in the production stability and is capable of presenting a constant quality, and a process for its production, which toner comprises a binder resin containing a crystalline resin, and wax, and which has, in its DSC curve measured by a differential scanning calorimeter, an endothermic peak of from 0.01 to 10 mJ/mg at a temperature of at most 45° C. during its temperature rise.
US08586273B2	Binder resin for toner, toner and method for producing same Disclosed is a binder resin for a toner containing at least a carboxyl group-containing vinyl resin (C), a glycidyl group-containing vinyl resin (E), a reaction product of the vinyl resins and a saturated crystalline polyester (S), wherein the saturated crystalline polyester (S) has a predetermined melting point and a predetermined metal component (M), and the binder resin for a toner has a predetermined loss modulus (G″) and a predetermined storage modulus (G′).
US08586272B2	Toner compositions The present disclosure provides toner compositions able to prevent the formation of mold or bacterial growth during storage. In embodiments, toners may include at least one biocide that prevents the formation of mold and/or bacteria in a toner composition, including any emulsion that may be utilized in forming the toner composition. In embodiments, the biocide may also improve charging characteristics of the toner.
US08586271B2	Toner composition having dual wax Included is an emulsion aggregation toner formulation having at least one latex and a combination of at least two waxes, wherein one wax is a synthetic wax, and another wax is a natural wax, and further including a developer containing a carrier and the just-described toner.
US08586270B2	Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus An electrophotographic photoconductor including: an electrically conductive substrate; and at least a photoconductive layer thereon, wherein the photoconductive layer contains a diazapentadiene derivative represented by general formula (1): where “X” represents general formula (a), (b) or (c); “R1” and “R2” each represent substituted or unsubstituted alkyl group or aromatic hydrocarbon group, and may be the same or different; “R1” and “R2” may be joined together via “Y” to form a ring; “Y” represents single bond, oxygen atom, —CH2CH2—, or —CH═CH—, where “R3” represents substituted or unsubstituted alkyl group, aromatic hydrocarbon group, alkoxy group, alkoxycarbonyl group, or halogen group; “R4” represents substituted or unsubstituted alkyl or aromatic hydrocarbon group; “n” represents integer ranging from 0 to 4; and when “n” is integer of 2 to 4, “R3” may be the same or different.
US08586264B2	Gas diffusion electrode material and production method thereof A gas diffusion electrode material of the present invention includes: a porous body (1) formed of continuous and discontinuous polytetrafluoroethylene microfibers (2) and having three-dimensionally continuous micropores (4); and a conductive material (3) supported on the porous body (1). Moreover, a density of the polytetrafluoroethylene microfiber (2) is lower in a surface region (1A) of a cross section of the porous body (1) than in an intermediate region (1B) of the cross section. In accordance with the present invention, the polytetrafluoroethylene having the predetermined three-dimensional structure is used, and so on. Therefore, it is possible to provide a gas diffusion electrode material excellent in power generation characteristics and durability.
US08586262B2	Titanium-based material, method of manufacturing titanium-based material, and fuel cell separator A method of manufacturing a titanium-based material includes: rolling a titanium base material via rolling oil that includes carbon to form a rolling-altered layer that includes titanium carbide on a surface of the base material; and depositing a carbon film on the surface on which the rolling-altered layer has been formed.
US08586261B2	Techniques for packaging and utilizing solid hydrogen-producing fuel Techniques for packaging and utilizing solid hydrogen-producing fuel are described herein. The fuel may be in the form of a bonded/compressed powder, granules, or pellets. The fuel is packaged in cartridges having hydrogen-permeable enclosures. In operation, the fuel undergoes a hydrogen-releasing Thermally Initiated Hydrolysis (TIH) reaction. A cartridge may comprise one or more fuel chambers, and several cartridges may be assembled together.
US08586253B2	Energy storage system A closed loop energy storage system configured with a hydrogen tank, an oxygen tank, a fuel cell stack and an electrolyzer. A heat exchanger freeze-dries the hydrogen and oxygen prior to their storage in their respective tanks. The heat exchanger also uses excess fuel cell heat to preheat streams of hydrogen and oxygen coming from the tanks. Phase separators serve both to separate water from hydrogen and oxygen, and to store the water. A thermal management system encloses all the system components except the tanks. An airfoil-shaped shell covers the system, and the larger of the two tanks extends substantially across the shell at its point of greatest camber thickness. The tanks are composed of polymer liners integral with composite shells.
US08586250B2	Non-aqueous electrolyte solution for storage battery devices, and storage battery device To provide a non-aqueous electrolyte solution for storage battery devices which has high lithium salt solubility, high conductivity and excellent cycle characteristics, and a storage battery device wherein such a non-aqueous electrolyte solution is used. A non-aqueous electrolyte solution for storage battery devices, which comprises a specific lithium salt (A) and a solvent (B) containing a hydrofluoroether (b1) represented by CF3CH2OCF2CF2H and a carbonate type solvent (b2), wherein the content of the hydrofluoroether (b1) is from 1 to 30 vol % based on the total amount i.e. 100 vol % of the solvent (B); and a storage battery device wherein such a non-aqueous electrolyte solution for storage battery devices is used.
US08586249B2	Electrolyte for lithium ion secondary battery and lithium ion secondary battery including the same The electrolyte for a lithium ion secondary battery includes a lithium salt, a non-aqueous organic solvent, gamma-butyrolactone and a wettability activator. The electrolyte for a lithium ion secondary battery provides excellent life characteristics and high-temperature stability and shows improved electrolyte pourability.
US08586243B2	Lead acid storage battery A lead acid storage battery composed of plates, the lead acid storage battery being obtained by packing an active material into a grid plate provided with a frame section having a quadrangular profile shape, and lateral grid strands and longitudinal grid strands that form a grid inside the frame section. The lateral grid strands are composed of thick lateral strands having a thickness equal to the thickness of the frame section, and thin lateral strands of smaller width and thickness than the thick strands, the longitudinal grid strands being composed of thick longitudinal strands that have a thickness that is less than thickness of the frame section, one end in the thickness direction being arranged in the same plane as one end of the frame section in the thickness direction, and thin longitudinal strands of smaller width and thickness than the thick longitudinal strands, end faces of one end side of the thin lateral strands and the thin longitudinal strands in the thickness direction being positioned further inward in the thickness direction than an end face of one end side of the frame section in the thickness direction, and end faces of the other end side of the thin lateral strands and the thin longitudinal strands in the thickness direction being positioned further inward in the thickness direction than an end face of another end side of the frame section in the thickness direction.
US08586242B2	Ferrous phosphate powders, lithium iron phosphate powders for LI-ion battery, and methods for manufacturing the same Ferrous (II) phosphate (Fe3(PO4)2) powders, lithium iron phosphate (LiFePO4) powders for a Li-ion battery and methods for manufacturing the same are provided. The ferrous (II) phosphate powders are represented by the following formula (I): Fe(3-x)Mx(PO4)2.yH2O (I) wherein, M, x, and y are defined in the specification, the ferrous (II) phosphate powders are composed of plural flake powders, and the length of each of the flake powders is 0.2-10 μm.
US08586240B2	Method of making tin-based alloys for negative electrode compositions Powder milling techniques, tin-based alloys formed thereby, and the use of such alloys as electrode compositions for lithium ion batteries are provided. The alloys include tin and at least one transition metal but contain no silicon. The powder milling is done using low energy roller milling (pebble milling).
US08586239B2	Positive electrode for lithium secondary batteries and use thereof The invention provides a positive electrode for lithium secondary batteries, comprising a conductive layer overlaid on the surface of a positive electrode collector, and an active material layer overlaid on the conductive layer, wherein the conductive layer comprises at least one water-insoluble polymer, as a binder, that is soluble in organic solvents, and a conductive material; the active material layer comprises at least one aqueous polymer, as a binder, that is soluble or dispersible in water, a positive electrode active material, and a conductive material; and the average particle size (DA) of the conductive material in the conductive layer is smaller than the average particle size (DB) of the conductive material in the active material layer.
US08586237B2	Method for manufacturing lithium secondary battery, lithium secondary battery, and lithium secondary battery system To provide a method for manufacturing a lithium secondary battery, characterized by having: a processing lithium secondary battery preparing step for preparing a processing lithium secondary battery that has a positive electrode layer containing LiFePO4 as a positive-electrode active material, a negative electrode layer containing a carbon material as a negative-electrode active material, and nonaqueous electrolyte solution containing LiPF6 and LiBOB; and a film forming step of performing a charging process on the processing lithium secondary battery until a voltage of the processing lithium secondary battery falls within a high voltage range in which a film of an oxidative decomposition product of a BOB anion contained in the LiBOB is formed on a surface of the positive-electrode active material.
US08586230B2	Battery module and method of manufacturing the same A battery module and a method of manufacturing the same, the battery module including a plurality of rechargeable batteries, each rechargeable battery including a positive electrode terminal and a negative electrode terminal formed of different materials; a bus bar electrically connecting the plurality of rechargeable batteries; a first terminal plate for installing the bus bar, the first terminal plate being coupled to the positive electrode terminal via a first welding portion; and a second terminal plate for installing the bus bar, the second terminal plate being coupled to the negative electrode terminal via a second welding portion, at least one of the first welding portion and the second welding portion being a friction stir weld.
US08586227B2	Low temperature sodium-beta battery A battery that will operate at ambient temperature or lower includes an enclosure, a current collector within the enclosure, an anode that will operate at ambient temperature or lower within the enclosure, a cathode that will operate at ambient temperature or lower within the enclosure, and a separator and electrolyte within the enclosure between the anode and the cathode. The anode is a sodium eutectic anode that will operate at ambient temperature or lower and is made of a material that is in a liquid state at ambient temperature or lower. The cathode is a low melting ion liquid cathode that will operate at ambient temperature or lower and is made of a material that is in a liquid state at ambient temperature or lower.
US08586223B2	Cylindrical secondary battery A secondary battery that includes a cylindrical can, an electrode assembly arranged in a jelly-role configuration within the cylindrical can and having a core extending about an axis thereof and a hollow center pin arranged within the core of the electrode assembly and having an inner diameter and an outer diameter, the outer diameter forming ones of a pair of radial lengths diametrically opposite from each other, each of said pair of radial lengths extending from the outer diameter of the center pin to an external surface of the core, wherein the sum of the pair of radial lengths is in the range of 5% to 54% of the inner diameter of the center pin.
US08586217B2	Protective circuit module A battery module including a battery including a connection terminal; and a battery cell; and a protective circuit module including a printed circuit board having an inner surface that faces the battery, an outer surface that opposes the inner surface, and a terminal opening, and including a conductive pattern around a periphery of the terminal opening and an insulating part around the periphery of the terminal opening, wherein the connection terminal extends from the battery cell to the outer surface of the printed circuit board through the terminal opening, the conductive pattern is coupled with the battery cell through the connection terminal, and the insulating part contacts a portion of the conductive pattern that is closest to the terminal opening.
US08586211B2	Asymmetrical aryl amine derivative for organic electroluminescence devices, method for preparing same, organic thin film for organic electroluminescence devices and organic electroluminescence device using same Provided are asymmetric arylamine derivatives for an organic electroluminescent element, represented by the formula (1), which is prepared by sequentially inducing a secondary amine and a tertiary amine to an aryl compound Ar core so that they do not include a symmetrical axis and a symmetrical surface in a molecule, a manufacturing method of the same, an organic thin layer material including the asymmetric arylamine derivatives, and an organic electroluminescent element employing the same: wherein Ar represents a C10-C20 divalent aryl group, Ar1 is a divalent C6-C30 aryl group, and Ar2 to Ar5 each independently represents a divalent C6-C30 aryl group, at least one of Ar2 to Ar5 having a different structure when the secondary amine and the tertiary amine in Ar are substituted at symmetrical positions, and Ar2 to Ar5 having the same structure or different structures when the secondary amine and the tertiary amine in Ar are substituted at asymmetrical positions. The asymmetric arylamine derivative can be used in forming an organic thin layer for an organic electroluminescent element. When the organic electroluminescent element is formed using a dopant as an emitting material, the asymmetric arylamine derivative exhibits superb emission efficiency and an excellent lifetime characteristic in a blue wavelength region.
US08586209B2	Opto-electrical devices and methods of manufacturing the same An improved composition for ink jet printing an opto-electrical device, which composition comprises a solution-processable host material and a metal complex, wherein the viscosity of the composition exceeds 12 mPa·s at 20° C.
US08586207B2	Fused polycyclic compound and organic light emitting device having the compound Provided are a fused polycyclic compound obtained by expanding the conjugated system of a chrysene skeleton, and an organic light emitting device using the compound. The organic light emitting device has an optical output with high efficiency and high luminance, and is extremely durable.
US08586204B2	Phosphorescent emitters and host materials with improved stability Devices containing a particular combination of organic compounds are provided. In particular, the devices contain twisted aryl compounds having extended conjugation (i.e., the twisted aryl is substituted with an additional aryl group) in combination with dibenzothiophene or dibenzofuran containing host materials. The organic light emitting devices may provide improved stability color, lifetime and manufacturing. Compounds containing a twisted aryl having extended conjugation are also provided.
US08586197B2	Composite material, light emitting element, light emitting device and electronic appliance using the composite material A composite material includes an organic compound represented by the following general formula (1) and an inorganic compound, where, in the general formula (1), R1 to R24 is identical to or different from one another, and represent any of hydrogen, an alkyl group, an alkoxy group, an aryl group, and an arylalkyl group. A light emitting element includes the composite material and a light emitting device and an electronic appliance includes the light emitting element. The composite material has an excellent carrier transporting property and an excellent carrier injecting property with respect to the organic compound along with high visible light transmittance. By utilizing the composite material, a current excitation type light emitting element requiring low driving voltage and having excellent light emitting efficiency is obtained. By using the light emitting element, a light emitting device consuming low power and an electronic appliance including the light emitting device is provided.
US08586194B2	Polycrystalline foams exhibiting giant magnetic-field-induced deformation and methods of making and using same Magnetic materials and methods exhibit large magnetic-field-induced deformation/strain (MFIS) through the magnetic-field-induced motion of crystallographic interfaces. The preferred materials are porous, polycrystalline composite structures of nodes connected by struts wherein the struts may be monocrystalline or polycrystalline. The materials are preferably made from magnetic shape memory alloy, including polycrystalline Ni—Mn—Ga, formed into an open-pore foam, for example, by space-holder technique. Removal of constraints that interfere with MFIS has been accomplished by introducing pores with sizes similar to grains, resulting in MFIS values of 0.12% in polycrystalline Ni—Mn—Ga foams, close to the best commercial magnetostrictive materials. Further removal of constraints has been accomplished by introducing pores smaller than the grain size, dramatically increasing MFIS to 2.0-8.7%. These strains, which remain stable over >200,000 cycles, are much larger than those of any polycrystalline, active material.
US08586192B2	Compatibilized polymeric compositions comprising polyolefin-polylactic acid copolymers and methods of making the same Polymeric compositions and processes of forming the same are described herein. The processes generally include contacting a polyolefin with a polylactic acid in the presence of at least 800 ppm of radical initiator under extrusion conditions to produce a polyolefin-polylactic acid copolymer.
US08586189B2	Gas-barrier film and organic device comprising same A gas-barrier film comprising at least one silicon hydronitride layer and at least one silicon nitride layer on a surface of a flexible supporting substrate. The film has an excellent gas-barrier property.
US08586188B1	Protective films or papers for glass surfaces and methods thereof A protective paper or film and a method of protecting a glass substrate by applying the protective paper or film having a slip agent composition onto a surface of a glass substrate. The slip agent composition comprises at least one fatty alcohol as defined herein.
US08586187B2	Adhesives for bonding polyurethane and aluminum The present invention provides an adhesive comprising graphene oxide including at an epoxy group, a hydroxyl group or a carboxylic acid group; and an alkoxysilane compound including an amine group, an epoxy group, a carboxylic acid group, a hydroxyl group, or a thiol group. More specifically the adhesive may be used for bonding a polyurethane elastomer to an aluminum material, in which a silane compound and graphene oxide are applied to improve adhesive strength, compared to adhesives including the silane compound only. In addition, during a separation process for recycling after use, the aluminum material and polyurethane can be easily separated from each other by polyurethane pyrolysis through rapid heating due to microwave absorption properties of graphene oxide.
US08586186B2	Pressure-sensitive adhesive sheet A pressure-sensitive adhesive sheet contains at least a pressure-sensitive adhesive layer containing an acrylic pressure-sensitive adhesive containing an acrylic polymer composition containing an acrylic polymer as a main component and a tackifier containing a tackifying resin as a main component, wherein reflection rate and attached amount in the fogging test in accordance with German Industrial Standard DIN 75201 are 70% or more and 2.0 mg or less, respectively. In the acrylic pressure-sensitive adhesive which forms the pressure-sensitive adhesive layer, a ratio of components having a molecular weight of 300 or less is preferably 4.2% by weight or less based on the total amount of solid matter of the acrylic pressure-sensitive adhesive. Furthermore, in the tackifying resin in the tackifier, a ratio of components having a molecular weight of 300 or less is suitably 4.2% by weight or less based on the total amount of solid matter of the tackifying resin.
US08586184B2	Fluorine-containing polymer and aqueous treatment agent Disclosed is a fluorine-containing polymer having (A) repeating units derived from a fluorine-containing acrylate monomer, and (B) repeating units derived from an amino group-containing monomer, wherein the fluorine-containing polymer is water-soluble. The fluorine-containing polymer has sufficiently high solubility, and can impart high water repellency, high oil repellency and high soil resistance to a porous substrate.
US08586177B2	Structural damage repair elements and kit Structural damage repair elements including inserts and a structural damage repair kit is provided. The structural damage repair elements typically include two or more layers of materials having an adhesive therebetween that are subsequently compressed together. The structural damage repair kit includes a chemical molding agent, an optional jig, one or more structural damage repair elements and a sealant. Both hollow and solid elongated objects, as well as relatively flat, curved objects may be repaired with the kit. The structural damage repair elements include rods, wafers, and/or adhesive saturated inserts.
US08586162B2	Electroconductive endless belt The present invention is an electroconductive endless belt used in an image forming apparatus in which a decrease with use in the gloss value caused by frictions and the like with papers and cleaning blade is suppressed. In the electroconductive endless belt, the base resin of the electroconductive endless belt comprises a polyalkylene terephthalate resin in combination with a naphthalene ring-containing thermoplastic resin and/or a naphthalene ring-containing thermoplastic elastomer having a melting point higher than that of the polyalkylene terephthalate resin, and the mass ratio of the polyalkylene terephthalate resin to the naphthalene ring-containing thermoplastic resin and/or the naphthalene ring-containing thermoplastic elastomer in the base resin is in the range of 90/10 to 50/50.
US08586161B2	Bags made from reclaimed plastic material and methods for making same Bags are formed from reclaimed plastic material. Each bag comprises two opposed sheet sections formed substantially entirely of a first polymer class, but also containing impurity particles of a different polymer class. The sheet sections comprise at least two distinct independent layers, with each layer in each sheet section being surface bonded to each adjacent layer in that sheet section. Although discontinuities in each layer resulting from the impurity particles create weak areas and in some cases apertures, the weakened portions of each layer are reinforced by portions of the other layer that are not weakened, since there is a minute likelihood that an impurity particle in one layer will be precisely co-located with an impurity particle in an adjacent layer. Thus, each layer reinforces the other layer to maintain structural integrity of the sheet section and of the bag. Methods for forming such bags are also described.
US08586158B2	Decorated plastic package There is here disclosed a plastic package (1) which has a thin-film layered structure (2) constituted of substances having different refractive indices and which is colored by an interference effect due to the thin-film layered structure (2). The plastic package is characterized in that, on a part of the surface of the plastic package, portions which are different in optical characteristics from the surface are periodically arranged.
US08586155B2	Display device A display device includes a display panel and at least one driving chip. The display panel has a display region and a non-display region and includes a pixel array, a plurality of pads, a passivation layer, and a plurality of conductive patterns. The pixel array is located in the display region. The pads are located in the non-display region and electrically connected to the pixel array. The passivation layer is located on the pads and has a plurality of through holes. Each of the conductive patterns covers one of the pads and is electrically connected to the pad through at least one of the through holes. A material of the conductive patterns includes a polymer conductive material. The driving chip is located on the display panel and electrically connected to the pads of the display panel.
US08586149B2	Environmentally friendly reactive fixture to allow localized surface engineering for improved adhesion to coated and non-coated substrates The present invention provides a method of increasing the surface energy of an article having a polymeric surface increasing the relative amount of nitrogen atoms or oxygen atoms within a portion of the surface to form a nitrogen or oxygen enriched surface layer. The method of the invention is advantageously applied to a vehicle body frame to facilitate adhesion of a windshield. In another embodiment of the invention a method for inhibiting sealer redeposition is provided in which a plastic component in an automobile is treated prior to being subjected to the various paint preprocessing baths.
US08586146B2	Multilayer surface covering with expanded supporting layer A method for manufacturing a multilayer surface coating including a PVC expanded surface layer is provided. The method includes the step of applying an aqueous composition including polyvinyl alcohol to the bottom portion of said supporting layer prior to the step of expanding said supporting layer.
US08586143B2	Capsules with a modified surface for grafting onto fibres The present invention relates to a method of grafting, by covalent bonding, hollow or solid composite capsules onto any type of natural, artificial or synthetic, organic or inorganic, support, the capsules being chemically, physically or physico-chemically modified, so as possibly to improve their affinity with the support and to functionalize them, and then grafted, after the capsules and/or the support have been activated. The invention also relates to the capsules thus modified, to the supports grafted by the capsules, especially fibres and textiles, and also to the use of these grafted supports, especially fibres and textiles, for making up what are called “functional” articles.
US08586142B2	Method and apparatus for producing small structures The present invention relates to a method for producing small structures includes: depositing a mask on a surface of a substrate; and evaporating a source material under such evaporation condition performed at such pressure to form a layer onto both a shadowed surface area and a non-shadowed surface area of the mask and the substrate.
US08586138B2	Method of coating a porous substrate with a thermoplastic material from the outside of the substrate A method of coating a first porous substrate with a thermoplastic material comprises the steps of: rotating the substrate about an axis of the substrate; and applying the material in a liquefied state onto the substrate, wherein the step of applying is performed from the outside of the substrate. According to another embodiment, a method of coating a porous substrate with a thermoplastic material comprises the steps of: connecting a first porous substrate to a rotator; rotating the substrate about an axis of the substrate; pumping the material in a liquefied state from a receptacle to an application head; and applying the material in a liquefied state onto the substrate, wherein the step of applying is performed from the outside of the substrate. In certain embodiments, the material coated on the substrate is used to help remove at least a portion of a filtercake.
US08586135B2	Method for manufacturing a colored electric wire An electric wire whose outer surface has a portion to be colored as required is manufactured by forming a plurality of recesses on the portion of the outer surface of the electric wire, which has a core wire and an insulating jacket that covers an entire periphery of the core wire, and then applying a coloring material to the portion of the outer surface of the electric wire. The recesses may be provided by blowing abrasive grains against the portion or by pricking the portion with one or more needles.
US08586133B2	Method for strengthening adhesion between dielectric layers formed adjacent to metal layers A method is provided which includes forming a metal layer and converting at least a portion of the metal layer to a hydrated metal oxide layer. Another method is provided which includes selectively depositing a dielectric layer upon another dielectric layer and selectively depositing a metal layer adjacent to the dielectric layer. Consequently, a microelectronic topography is formed which includes a metal feature and an adjacent dielectric portion comprising lower and upper layers of hydrophilic and hydrophobic material, respectively. A topography including a metal feature having a single layer with at least four elements lining a lower surface and sidewalls of the metal feature is also provided herein. The fluid/s used to form such a single layer may be analyzed by test equipment configured to measure the concentration of all four elements. In some cases, the composition of the fluid/s may be adjusted based upon the analysis.
US08586130B2	Increasing exposure tool alignment signal strength for a ferroelectric capacitor layer An improved alignment structure for photolithographic pattern alignment is disclosed. A topographical alignment mark in an IC under a low reflectivity layer may be difficult to register. A reflective layer is formed on top of the low reflectivity layer so that the topography of the alignment mark is replicated in the reflective layer, enabling registration of the alignment mark using common photolithographic scanners and steppers. The reflective layer may be one or more layers, and may be metallic, dielectric or both. The reflective layer may be global over the entire IC or may be local to the alignment mark area. The reflective layer may be removed during subsequent processing, possibly with assist from an added etch stop layer, or may remain in the completed IC. The disclosed alignment mark structure is applicable to an IC with a stack of ferroelectric capacitor materials.
US08586124B2	Candy and method for producing the same The present invention includes a candy and a method for producing it which solves the following problems: crystallization control, continuous production for mass production when the candy includes crystallization of xylitol; prevention of deterioration of the perceived coolness of xylitol, and loss of moisture absorption stability.The includes xylitol and erythritol, wherein the candy is produced by a method including the steps of: heating and melting a compound containing xylitol and erythritol at a weight ratio ranging from 99:1 to 80:20; forming a preliminary product that keeps the melted sugar liquefied in a partly or fully crystallized xylitol fluid by maintaining a fluidity temperature which is below the melting point of xylitol forming the preliminary product into a desired shape; and cooling the formed product to room temperature.
US08586123B2	Food composition The present invention relates to the use of the compounds a) 3-hydroxy-2(H)-furanones, preferably, 3-hydroxy-4,5-dialkyl-2(H)furanones, b) thiol-substituted methylfuranes, thiol-substituted methyl di/tetra-hydro furanes, or dithiolanes, preferably furfurylthiol, 2-methyl-3-tetrahydrofuranthiol or 2-methyl-1,3-dithiolane, c) furfuryl alcohol, d) bis(2-methyl-3-furanyl)disulphide as a sodium-replacing agent in food compositions. Furthermore, the invention relates to a ready-to-eat and a concentrated food composition which may comprise less sodium than conventional comparable ready-to-eat or concentrated food compositions, respectively, but which food compositions are experienced by the consumer as having a flavor which is comparably salty as that of a conventional comparable composition. Furthermore, the present invention relates to a method to reduce the sodium content of a food composition by replacing sodium by the above mentioned compounds.
US08586122B2	Composition suitable for use in baking A composition comprising: (A) from about 20% to about 80% by weight of an interesterified palm oil olein; (B) from about 5% to about 25% by weight of a liquid oil; (C) from about 15 to about 75% by weight of a fat selected from the group consisting of palm oil stearins, interesterified palm oil stearins, palm oil oleins, fully hydrogenated oils and mixtures thereof may be used as a bakery fat, particularly a laminating fat for products such as puff pastry.
US08586120B2	Production of whole grain shredded products Shredded whole grain products, such as ready-to-eat cereals, and sweet and savory snacks, such as whole grain shredded corn chips are continuously produced by pelletizing agglomerates of cooked, tempered, whole cereal grain particles. Cooked whole grains, such as corn and other non-gluten or low-gluten containing grains have a tendency to become hard and rubbery after cooking during the cooling and tempering process. The pelletization results in the production of whole grain pellets having a soft, pliable texture, which are shreddable into continuous net-like sheets on a mass production basis. The pelletizing may be at a pressure of about 200 psig to about 600 psig, preferably from about 400 psig to about 500 psig. The pelletizing temperature may be controlled to provide a pellet temperature of about 80° F. to about 120° F., preferably from about 90° F. to about 110° F., upon exiting the pelletizer.
US08586119B2	Distributing products which comprise coconut water The present invention relates to a method of distributing products which include a coconut water, the method including: procuring a coconut water that has been extracted from a coconut in a manner that prevented oxygen from contacting the coconut water during extraction from the coconut; manufacturing a product that includes at least a portion of the coconut water; and distributing the product to consumers. Additional embodiments of the present invention include extracting the coconut water by way of injecting a gas into the coconut, placing the coconut in a chamber and removing oxygen from around the coconut, collecting and utilizing coconut water collected in a manner which minimizes carbon emissions impact, packaging the product in a package material which includes a barrier property that abates oxygen transfer, and extending the consumer benefit of the coconut water by distributing the product through a refrigerated supply chain.
US08586118B1	Method of using a gravity wheel de-stemmer A produce de-stemmer for generally symmetrical produce such as pepper pods that supports an item of produce in a propped orientation within a canister, a number of which are connected to a moving endless chain so that the canisters are cyclically inverted. A fixed support track resides below the moving canisters to support the item of produce so that a portion of the item is exposed during the canister travel. The exposed portion of the produce item is propelled into a cutting means which removes a desired portion of the produce item.
US08586117B2	Liquid infusion process and method of brewing a beverage A liquid infusion and/or brewing process is described. The process includes the steps of placing a desired amount of an infusion material into a chamber at atmospheric pressure, placing a desired amount of liquid into said chamber, sealing said chamber from the surrounding atmosphere, and applying at least one reduced pressure cycle within said chamber, wherein said at least one cycle includes reducing pressure within said chamber to form at least a partial vacuum within said chamber and subsequently returning said chamber to about atmospheric pressure. Methods for separating the brewing media from the liquid after completion of the brewing process are also described.
US08586114B2	Method for producing stinky brine for use in production of stinky tofu and fermentation broth used therefor A method for producing stinky brine for use in production of stinky tofu and a fermentation broth used therefore is provided. The method for producing stinky brine includes steps of inoculating a fermentation broth with microflora for producing the stinky brine. The fermentation broth includes at least 85˜153 g/L of tryptone and 15˜27 g/L of soytone, which may further include a trace amount of glucose, sodium chloride, dipotassium phosphate or a combination thereof.
US08586112B2	Treatment of parasitic infections in humans and animals The invention provides a process for the production of a substance or composition for the treatment, by therapy or prophylaxis, of parasitic infections, in particular malarial infections such as Plasmodium falciparum infections, of the human or animal body. The process comprises extracting the substance or composition from roots of the plant species Dicoma anomala, by an extraction using an organic solvent to obtain a liquid extract containing the substance or composition and removing the solvent from the liquid extract to leave a dried extract containing the substance or composition. The invention extends also to the use of the substance or composition in the manufacture of a medicament or preparation for such treatment of infections; to a substance or composition for use in such treatment of said infections; to compounds for use in such treatment of said infections; and to a method of treating said infections using such compounds.
US08586111B2	Method of applying a protective film over natural hair or scalp prior to application of bonding glue The hair gluing product of the invention is gel or crystallizing protective growth serum that dries down to form a film over your natural hair and scalp. The invention allows for application of hair bonding glue without damaging natural hair or scalp. It contains aloe extract, tea tree oil, chamomile extract. It is available in an assortment of colors. The purpose of the gel or serum is to protect client's natural hair/scalp from being damaged by the use of hair bonding glue, which is used for weaving styles. When hair bonding glue is applied directly to the natural hair and scalp it has a tendency to cause breakage and leads to damage hair the invention will cover the natural hair, which will allow the hair bonding glue to be applied directly to the shield that appears after the invention dries on the hair/scalp.
US08586108B2	Extracts of Chenopodium ambrosioides L., the compositions comprising said extracts, the preparing process and application thereof The present invention relates to plant extracts, specifically, the extracts of Chinese medicine Chenopodium ambrosioides L. and the composition comprising thereof. The extracts of Chinese medicine Chenopodium ambrosioides L. are prepared by conventional methods for the extraction of volatile oil, and can be used to treat Helicobacter Pylori-induced diseases of digestive system, such as gastritis, gastric ulcer, etc., with easy availability of raw materials, simple preparations, prominent effects, and less side-effect.
US08586107B2	Schisandra sphenanthera fruit extract and cosmetic, dermatological, and nutraceutical compositions comprising same A cosmetic, dermatological or nutraceutical composition including a Schisandra sphenanthera fruit peptide and sugar extract, a crude oil, a refined oil, a refined oil concentrate, and/or the unsaponifiable fraction of the concentrate. A method for preparing a peptide and sugar extract, a refined oil, and/or a concentrate and an unsaponifiable fraction of oil of the Schisandra sphenanthera fruit.
US08586100B2	Populations of hematopoietic stem cells Described herein are methods for purifying hematopoietic stem cells. Also described herein are methods for purifying EPCR+ cells. The invention also provides substantially pure isolated hematopoietic stems cells, including EPCR+ hematopoietic stem cells.
US08586099B2	Method for preparing a prion-free bond grafting substitute The present invention relates to a method for preparing a bone graft substitute using bovine bone, and more particularly to a method for preparing a safe bone graft substitute which does not have the risk of infection with bovine spongiform encephalopathy, the method comprising treating bovine bone with sodium hypochlorite and treating the treated bone at a high temperature of more than 600° C. The bone graft substitute does not cause an immune response, because it is prepared by effectively removing lipids and organic substances from bovine bone having a structure very similar to that of the human bone. Also, it has excellent osteoconductivity, and is free of prion, and thus it does not have the risk of infection with bovine spongiform encephalopathy. According to the disclosed invention, the bone graft substitute having such advantages can be prepared in a simple manner.
US08586095B2	Thermosensitive nanostructure for hyperthermia treatment A thermosensitive nanostructure for hyperthermia treatment. Magnetic nanoparticles are encapsulated in a thermosensitive polymer nanostructure having a lower critical solution temperature (LCST) of about 40-45° C. The thermosensitive polymer nanostructure may carry a drug. When the magnetic nanoparticles are heated to 40-45° C. by application of an alternating magnetic field in hyperthermia treatment, the thermosensitive polymer nanostructure collapses to release the drug, thus providing concurrent drug treatment.
US08586094B2	Coated tablets Disclosed is a pharmaceutically acceptable oral dosage form comprising fenofibrate, phospholipid, a buffer salt, a water-soluble bulking agent selected from maltodextrin, mannitol, and combinations thereof, a cellulosic additive, beads or crystals of a pharmaceutically acceptable water-soluble excipient support material, a polyvinylpyrrolidone or crospovidone, croscarmellose sodium, granular mannitol, sodium dodecyl sulfate, silicon dioxide, and a stearate, wherein the fenofibrate is in the form of microparticles, and wherein at least a portion of the phospholipid is coated on the surfaces of the fenofibrate microparticles, the phospholipid coated microparticles are embedded in a matrix comprising the water-soluble bulking agent, phospholipid that is not coated on the microparticles, the buffer salt and the cellulosic additive, and the matrix is coated on up to 100% of the surfaces of the beads or crystals of the excipient support material.
US08586086B2	Hydrogel capable of containing and conveying cells An interpenetrating biodegradable polymeric matrix hydrogel and the use thereof to support, encapsulate, convey and release several types of cells under conditions which allow the cells to be kept alive, grow and interconnect. The hydrogel may be used to prepare implants for integrally or partially regenerating, reconstructing and/or replacing damaged, dead or no longer functional tissues, in particular at the central nervous system or spinal marrow level. In such use, the biodegradability of the hydrogel allows a progressive release of the conveyed cells in order to promote their integration, even functional, with the surrounding tissue. The hydrogel may also be employed to support cells, for example, neural cells such as neuronal cells, on measuring devices, specifically realized for monitoring several parameters of cell activity, also during pharmacological and bio-mechanical tests.
US08586084B2	Modified release compositions comprising tacrolimus A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro dissolution test using USP Paddle method and using 0.1 N HCl as dissolution medium and has increased bioavailability by effectively reducing or even avoiding the effects of CYP3A4 metabolism. The modified composition may be coated with an enteric coating; and/or may comprise a solid dispersion or a solid solution of tacrolimus in a hydrophilic or water-miscible vehicle and one or more modifying release agents; and/or may comprise a solid dispersion or a solid solution of tacrolimus in an amphiphilic or hydrophobic vehicle and optionally one or more modifying release agents.
US08586081B2	Detoxified recombinant botulinum neurotoxin The present invention relates to the isolation of polypeptides derived from the Clostridium botulinum neurotoxin and the use thereof as immunogens for the production of vaccines and antitoxins, as well as research and drug development applications. Clostridium botulinum is responsible for food bone botulism, a severe and often deadly disease. Botulinum neurotoxin binds to neural cells and are translocated into the cytosol. The toxin then prevents neurotransmitter release by cleaving a SNARE protein. A double mutant E224A/E262 full length botulinum neurotoxin Type A holo form was successfully cloned and purified, which lacks the endopeptidase activity involved in the toxic action of the BoNT, and thus leading to its detoxification (DR BoNT/A). This new molecule can be used as an antidote against botulism, and also as a vaccine candidate for botulism. Due to the poor availability and extreme toxicity of native holo-toxin, a nontoxic form of the holo-toxin is highly desired for research and vaccine development. The full length DR BoNT/A protein has been expressed in E. coli as a soluble form.
US08586075B2	Coatings for implantable devices comprising poly(hydroxy-alkanoates) and diacid linkages Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings include block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
US08586074B2	Calcium sulfate composite particles including aggregated calcium sulfate nanoparticles and method of use for bone augmentation Calcium sulfate composite particles for bone augmentation are disclosed. The composite particles are composed of aggregated calcium sulfate nanoparticles of a diameter from about 50 to about 800 nm, which include a mixture of calcium sulfate dihydrate and calcium sulfate hemihydrate. The composite particles have a diameter from about 200 to about 1,200 μm, and a mean half-life no less than 18 days. Further disclosed is a bone grafting material for bone augmentation. The bone grafting material includes a mixture of the calcium sulfate composite particles and a second type of calcium sulfate particles having a particle diameter from about 2 to about 60 μm, at a ratio from 1:1 to 4:1. The method of using the composite particles and the bone grafting material for bone augmentation is also disclosed.
US08586073B2	Methods and formulations for administration of resolvin anti-inflammatory compounds The invention relates to resolvins and their use as anti-inflammatory compounds. The resolvins may be administered in a variety of forms, including drug depots comprising polymers or lipids. The pharmaceutical formulations of the present invention may be used to treat a variety of conditions including acute pain and chronic pain.
US08586069B2	Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque.
US08586062B2	Nanodispersion The present invention provides a nanodispersion comprising nanoparticles having a mean size less than 300 nm dispersed in a vehicle comprising a water miscible solvent and water, said nanoparticles comprising one or more taxane derivative, a polymer and a surfactant comprising a mixture of fatty acids or its salts and sterol or its derivatives or its salts.
US08586061B2	Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
US08586058B2	Method for producing multiple modifications in the chromosome of gram-negative bacteria and salmonella strains which are deficient in c-di-GMP synthesis obtained by said method Method for producing multiple modifications in the chromosome of Gram-negative bacteria and Salmonella strains which are deficient in c-di-GMP synthesis obtained by said method. The method can be used to make multiple modifications in the genome of Gram-negative bacteria, simply and efficiently, using the plasmids of the invention, which comprise a marker gene under the control of a constitutive promoter, a replication origin specific for Gram-negative bacteria, a gene which encodes a heat-sensitive protein essential for initiating replication of the plasmid, making the replication origin heat-sensitive, and a counter-selection gene. The invention also relates to mutant Salmonella enterica strains obtained using the method of the invention in which some of the twelve genes which encode proteins with GGDEF domain have been selected*, and to the use thereof as expression vectors, immunotherapeutic agents and in metabolic studies.
US08586057B2	Enterohemorrhagic Escherichia coli vaccine Compositions and methods for stimulating an immune response against a secreted enterohemorragic Escherichia coli (EHEC) antigen are disclosed. The compositions comprise EHEC cell culture supernatants.
US08586056B2	HIV-1 envelope glycoprotein The present application relates to a novel HIV-1 envelope glycoprotein which may be utilized as an HIV-1 vaccine immunogen, antigens for crystallization and for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
US08586055B2	DNA immunization protocols This invention provides DNA vaccines for the treatment of patients undergoing anti-retroviral therapy. The vaccines are surprisingly effective at controlling viremia.
US08586054B2	Method for modulating, treating and/or preventing metabolic syndrome using MAS-G-protein-coupled receptor agonists The present invention is characterized by the use of Mas-G-protein-coupled receptor agonists for the control, prevention and treatment of the body levels of triglycerides, cholesterol and glucose, as well as of hyper-tension and possible increase in body weight, which are characteristic of the clinical manifestation of the metabolic syndrome and its complications. Another characteristic of the invention is the use of Mas-G-protein-coupled receptor agonists, including the Angiotensin-(1-7) peptide and its analogs, agonists, either peptidic or non-peptidic, as modulators of the manifestations of insulin resistance and glucose intolerance and in the prevention and treatment of the related alterations. The invention claims the use of MAS-G-protein-coupled receptor agonists, formulated with pharmaceutically and pharmacologically acceptable excipients or carriers, and Mas-G-protein-coupled receptor agonists, including the Angiotensin-(1-7) peptide and its analogs, agonists, either peptidic or non-peptidic, as modulators of the metabolic syndrome, the diseases that compose it and its complications.
US08586051B2	Glycolipids and analogues thereof as antigens for NKT cells This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses.
US08586047B2	Genetic products differentially expressed in tumors and the use thereof The present technology relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the present technology also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.
US08586046B2	Methods and compositions for mycoplasma pneumoniae exotoxins The present invention provides a Mycoplasma pneumoniae community acquired respiratory distress syndrome (CARDS) toxin, biologically active fragments/domains of the CARDS toxin, antibodies to the CARDS toxin and nucleic acids encoding the CARDS toxin. Also provided are methods of diagnosing, treating and/or preventing infection by Mycoplasma pneumoniae using the compositions provided herein.
US08586040B2	Methods of using apoptotic anti-IGE antibodies The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
US08586035B2	Use of IL-23 antagonists for treatment of infection Methods and compositions comprising antagonists of IL-23 are provided for the treatment of infections, such as chronic bacterial, viral and fungal infections.
US08586034B2	Cytomegalovirus disintegrin-like peptides The present invention relates to methods and compositions for inhibiting the entry of viruses, such as herpesviruses into a host cell. A conserved viral integrin-binding gB disintegrin-like domain has been identified that engages integrins and facilitates viral internalization into the host cell. Therefore, methods and compositions, such as antiviral agents encompassing the conserved gB disintegrin-like domain and antibodies thereto are described. These active agents interfere with the interaction between virions and cellular integrins, thereby inhibiting viral infection of a host cell.
US08586027B2	Composition to obtain a biological fungicide and bactericide without the use of antibiotics to control plant diseases etc A composition used to obtain a biological fungicide and bactericide without the use of antibiotics to control plant diseases, consisting in native strains. The composition is characterized in that it includes strains of the bio-controllers Bacillus spp and Brevibacillus parabrevis in a concentration of ten to the power of eight spores/g at a ratio of 1:1:1:1 for each of the strains, with a broad-spectrum action on phytopathogenic bacteria and late blight.
US08586025B2	Method of inhibiting methanogenesis The object of the present invention is to provide a technique to inhibit methanogens from producing methane. The use of Alcaligenes faecalis can inhibit methanogens from producing methane.
US08586024B2	Long lasting drug formulations The present invention is directed to long-lasting therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a vector which comprises a nucleic acid sequence operably linked to one or more regulatory sequences, wherein the nucleic acid sequence encodes a therapeutic polypeptide, such as erythropoietin or interferon alpha.
US08586023B2	Cell capable of expressing exogenous GITR ligand Disclosed are: a cell capable of expressing an exogenous GITRL or an exogenous GITRL derivative; a method for producing the cell; a therapeutic or prophylactic agent comprising the cell as an active ingredient; use of the cell in the manufacture of a therapeutic or prophylactic agent; a method comprising a step of administering the cell to a subject; a viral vector carrying a gene encoding a GITRL or a GITRL derivative; a therapeutic or prophylactic agent comprising the viral vector as an active ingredient; use of the viral vector in the manufacture of a therapeutic or prophylactic agent; and a method comprising a step of administering the viral vector to a subject.
US08586020B2	Poly(organophosphazene) composition for biomaterials Provided are a use of chemically-crosslinkable, poly(organophosphazene)s for biomaterials, chemically-crosslinkable poly(organophosphazene)s with a physiologically active substance covalently-bonded thereto, a use thereof for biomaterials, and a process for preparing the same. The chemical crosslinkings can be made by UV irradiation, and/or a crosslinker, and/or an additive, and/or an enzyme, and/or a mixing of at least one polymer.
US08586017B2	Self-heating non-aerosol shave product Self-heating non-aerosol shave products are provided. In some implementations, the shave product includes a non-ionic emulsifier system, for example, including one or more fatty alcohol ethoxylates.
US08586014B2	Composition for the care of keratin material and cosmetic treatment process using said composition The present disclosure relates to a cosmetic composition for the care of keratin materials and which comprises, in an aqueous medium: at least one silicone, at least one mono- or diester of a fatty acid and of ethylene glycol or of polyethylene glycol, and at least one ester of a C8 to C14 fatty acid and of an oxyethylenated sorbitan comprising from 2 to 10 oxyethylene units. The present disclosure also relates to a process for the cosmetic treatment of keratin materials using the composition.
US08586013B2	Comfortable, long-wearing, transfer-resistant colored cosmetic compositions having a non-tacky feel The present invention is directed to an anhydrous composition which is long wearing and transfer resistant, while at the same time providing superior comfort, non-tacky feel and cushioning, the composition containing: (a) at least one silsesquioxane resin; (b) at least one polypropylsilsesquioxane wax substituted with alkyl units having at least 30 carbons; (c) at least one siloxysilicate resin; (d) at least one volatile solvent; (e) optionally, at least one non-volatile solvent; and (f) at least one colorant.
US08586011B2	Skin coating composition and uses thereof A composition for coating skin comprising shellac, ethanol, castor oil, ethyl cellulose and fumed silica or nano zinc oxide, wherein the composition forms a long lasting waterproof flexible film on skin. The composition may include different ingredients for different applications. In one embodiment, the composition includes pigment and/or dye and may be used to coat a skin blemish such that the skin blemish blends in with the surrounding skin. In another embodiment, the composition includes a sunscreen agent and may be used as a sunscreen. In yet another embodiment, the composition includes a therapeutic agent for treating a disorder of the skin.
US08586008B2	Pharmaceutical foam The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelf-life of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics.
US08586006B2	Organ-specific proteins and methods of their use The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific proteins and transcripts encoding the same, detection reagents for detecting such proteins and transcripts, and diagnostic panels, kits and arrays for measuring organ-specific proteins/transcripts in blood, biological tissue or other biological fluid.
US08586005B2	Ultrasound contrast agent dosage formulation Clinical studies have been conducted and specific dosage formulations developed using polymeric microparticles having incorporated therein perfluorocarbon gases that provide significantly enhanced images of long duration. The dosage formulation includes microparticles formed of a biocompatible polymer, preferably including a lipid incorporated therein, and containing a perfluorocarbon that is a gas at body temperature. The microparticles are provided to a patient in an amount effective to enhance ultrasound imaging in the ventricular chambers for more than 5 minutes or in the mycocardium for more than a minute, in a dose ranging from 0.025 to 8.0 mg microparticles/kg body weight. Preferably the dose ranges from 0.05 to 4.0 mg microparticles/kg body weight. The dosage formulation typically is provided in a vial. A typical formulation is in the form of a dry powder that is reconstituted with sterile water prior to use by adding the water to the vial or syringe of the dry powder and shaking to yield an isosmotic or isotonic suspension of microparticles.
US08586001B2	Energy recovery in manufacture of sulfuric acid This invention relates to the recovery of energy in the manufacture of sulfuric acid, and more particularly to enhanced recovery of energy from the absorption of wet SO3 in sulfuric acid. The invention is further directed to control of mist formation during SO3 absorption, and of the sulfuric acid mist content of the gas stream leaving the SO3 absorption step in a process wherein SO3 absorption energy is recovered from absorption acid in useful form.
US08586000B2	Random graphite and fabrication method thereof using graphene nanoribbon A graphite material and corresponding methods of fabricating the graphite material from graphene nanoribbons are described. The graphite material is composed of a multiplicity of graphene nanoribbons which are randomly layered on each other. The graphene nanoribbons are less than 0.4 nm thick, 5 nm wide, and 20 nm long. One variant of the method of fabricating the graphite material includes preparing graphene nanoribbons, suspending the graphene nanoribbons in a solvent, and then drying the suspension to fabricate the graphite material and to drive off the solvent.
US08585997B2	Process and an apparatus for converting solid organic materials into carbon or activated carbon A process and an apparatus for converting solid organic materials into carbon or activated carbon. The processing of solid organic materials is oxygen-free and wholly under endothermic condition. The apparatus comprises a pressure vessel (1), thermal insulation with protective cladding for pressure vessel (2), a perforated or non-perforated rotary drum (3), a sealed dish end (4), a rotating shaft (5), a geared motor with belt or chain drive (6), a steam super heater (7) for generating superheated steam, at least one inlet valve (8) for regulating the super heated steam, at least one feed pipe (9), tilting or swivel support (10), at least one cylindrical roller (11), an open or close door end (12), a feeding or removal port (13), a connecting chute (14), at least one pressure safety valve (15), a gas exit pipe (16), at least one outlet valve (17), a gas treatment unit (18) for treating the generated reaction gases, at least one pressure gauge (19) and at least one temperature indicator (20). The pressure vessel is tilted along with its accessories supported on a tilting or swivel support and solid organic materials are feeded into the rotary drum and then realigned. Gas or steam is feeded inside the pressure vessel till the entire air inside the pressure vessel is purged out and thereafter superheated steam continuously feeded into the rotary drum. The rotary drum is constantly rotated by geared motor and generated reaction gases are evacuated from the pressure vessel to the gas treatment unit wherein the organic solid materials are converted into carbon or activated carbon.
US08585988B2	Method for creating traceable tissue sample cassettes with RFID technology The present invention relates to a method to turn cassettes for biological tissue samples into devices traceable with RFID technology, using a system with inlays tagged with an RFID chip, which inlays are placed in the tissue sample chamber of the tissue cassettes, wherein the part of the inlay that contains the antenna of the RFID chip is running around an opening or is folded together. Such inlays do not risk being affected by damaging forces outside the tissue cassettes. With an inlay that at every suitable moment can be positioned in the tissue sample chamber for one or more limited periods of time, or indefinitely, tissue cassettes can be tracked and traced with RFID technology without the fear of destroying the RFID chip during processing that involves the use of a microwave oven. During that period the inlay can be temporarily removed from the tissue cassette.
US08585986B1	Capillary interconnect device An interconnecting device for connecting a plurality of first fluid-bearing conduits to a corresponding plurality of second fluid-bearing conduits thereby providing fluid communication between the first fluid-bearing conduits and the second fluid-bearing conduits. The device includes a manifold and one or two ferrule plates that are held by compressive axial forces.
US08585983B2	Halogen and heavy metal-free composition for a humidity indicating device and humidity indicating device containing the same The disclosed invention is a composition for a humidity indicating device comprising (a) an organic pH indicator dye compound, (b) a Bronsted acid or base, and (c) a polyol having the general formula HOCH2—(CHOH)n—CH2OH, wherein n can be 0, 1, 2, 3 or 4, wherein said components (a), (b), and (c) do not contain halogen and/or heavy metals. Furthermore, the invention relates to a humidity indicator device comprising a sheet substrate and the composition for a humidity indicating device containing no heavy metals or halogen compounds, and to a process for preparing said humidity indicator device.
US08585979B2	Enhanced photo-catalytic cells A photo-catalytic cell may produce bactericidal molecules in air by passing air across catalyst coated targets. Ultraviolet (UV) energy may be emitted from a source. A first portion of the UV energy from the source may be applied directly onto the targets. A second portion of the UV energy from the source may be reflected onto the targets.
US08585976B2	Devices for selective removal of contaminants from a composition A device for selectively removing contaminants from a crude product mixture which includes a production reactor for producing a crude oil product mixture, the production reactor includes a lipid reservoir and an alcohol reservoir and a first organic acid removal reactor in fluid communication with the production reactor. The first organic acid removal reactor includes a first housing defining an interior volume the housing configured to receive the crude oil products and disposed within the interior volume of the removal reactor housing is metal oxide media selected from the group consisting of zirconia, alumina, hafnia and titania for removing organic acidic contaminants from the crude oil product to product a purified biodiesel fuel.
US08585969B2	Device and methods for processing blood in extracorporeal circulation A device for treating blood in an extracorporeal blood circuit, the device including a centrifugal pump provided with a transparent enclosure that is connected, by means of an inlet duct, to the outlet of a venous reservoir, the venous reservoir having an inlet that is connected to receive blood from a patient. The transparent enclosure of the pump is connected monolithically to the base of a structure that comprises a heat exchanger and an oxygenator. The structure also supports monolithically, at the peripheral region, an arterial filter that receives the blood in output from the oxygenator and is provided with a connector for coupling to an arterial line for return of the blood to the patient.
US08585966B2	Method of antifungal and antibacterial drying of footwear and an apparatus for electro-drying of footwear This invention relates to means for footwear care and also can be used for cleansing of footwear. The method of antifungal and antibacterial drying of footwear includes simultaneous processes of heating and ultraviolet treatment, wherein optimum combination of thermal and ultraviolet treatments can be chosen. The apparatus for antifungal and antibacterial electro-drying of footwear includes heating elements (4), ultraviolet lamps (5), and two bodies (1,2). The heating element and ultraviolet lamps are disposed inside each of the bodies. Present invention provides reliable preventive care of footwear by means of coordinated simultaneous processes of heating and ultraviolet treatment.
US08585965B2	Sterilization of polymeric materials A method of sterilizing a polymeric material that is sensitive to radiation. The method includes the steps of applying at least one radiosensitizer to the polymeric material and irradiating the polymeric material with a suitable radiation at an effective dose and time to sterilize the polymeric material. Also disclosed is a method of enhancing the ability of a medical device to withstand sterilization by radiation and a bioabsorbable polymeric medical device.
US08585962B2	Non-ferrous metal melt pump and melting furnace system using the same Provided are a non-ferrous metal melt pump having a simple structure capable of tapping non-ferrous metal melt at a low cost without the help of a person, and a melting furnace system using the same. The non-ferrous metal melt pump includes: a container body which includes an inner space and a non-ferrous metal melt passageway, the non-ferrous metal melt passageway having a spiral passageway formed inside a side wall so that a lower end inlet and an upper end open portion, respectively formed in the side wall to be open to the outside, communicate with each other; a magnetic field device, which is rotatable about the vertical axis line, arranged inside the inner space, and the magnetic field device having a magnitude of a magnetic field such that lines of magnetic force moves while penetrating non-ferrous metal melt inside the spiral passageway during the rotation; and a drive device which rotationally drives the magnetic field device.
US08585961B2	Preheaters for preheating steelmaking ladles Embodiments of the invention comprise a preheater for preheating a ladle for use in steelmaking wherein less fuel is consumed in heating the ladle efficiently and accurately to a controlled temperature. A preheater temperature is varied by controlling a burner of the heating unit based on measurements of refractories of the ladle taken by a pyrometer. The heating unit of the preheater includes an emissive coating for reducing heat loss and efficient heating during the preheating process. The heating unit of the preheater also includes valve mechanisms for accurately varying a flame size of the burner by regulating the rate of fuel, air, and oxygen supplied to the heating unit.
US08585960B2	Method for producing sintered body, and sintered body A first inorganic powder molded body and a second inorganic powder molded body are obtained. Each of the bodies contains an inorganic powder, an organic dispersion medium having a reactive functional group and a gelling agent and is solidified by chemical reaction of the organic dispersion medium and the gelling agent. Slurry containing a powder component and an organic dispersion medium is applied to a joint surface of the first inorganic powder molded body. The inorganic powder molded bodies are allowed to abut on each other while interposing the slurry therebetween, and integrated together into a joined body. A sintered body is obtained by sintering the joined body.
US08585959B2	Balloon with integrally retained dilation element A balloon catheter is provided with integral tubular extensions for securing dilation elements to the outside of the balloon. The dilation elements are disposed within the tubular extensions along the working diameter of the balloon. The balloon may be manufactured by extruding a parison and blow molding the parison with the dilation elements installed within the tubular extensions.
US08585957B2	Method of manufacturing nano-fiber non-woven fabrics A method of manufacturing nano-fiber non-woven fabrics is provided. The method comprises preparing a polyurethane solution by dissolving polyurethane in an organic solvent, producing an electrospinning solution by adding far infrared ray emitting particles, antibacterial inorganic particles, and deodorization inorganic particles to the polyurethane solution, and electrospinning the electrospinning solution to form the nano-fiber non-woven fabric. The far infrared ray emitting particles may be obtained by adding a metal oxide to ceramics and sintering the metal oxide-added ceramics. The antibacterial inorganic particles may be obtained by impregnating a zirconium-based carrier with silver ions. The deodorization inorganic particles may be obtained by impregnating a zirconium-based or a silica oxide-based carrier with an amine-based compound.
US08585956B1	Systems and methods for laser marking work pieces A method of laser marking a work piece involves reproducing a pattern having a surface marked portion and a depth engraved portion from a digital image of the pattern. The grayscale shades of pixels in one portion of the image are adjusted while maintaining grayscale shades of pixels in the other portions of the image constant, wherein the adjusted grayscale shades of pixels corresponding to a surface marked portion are within a first range and the adjusted grayscale shades of pixels corresponding to a depth engraved portion are within a second range separate from the first range. The modified image is converted to a computer readable code, such that the first and second ranges of grayscale shades are associated with surface marking and depth engraving ranges of laser power settings. A laser marking apparatus is then operated in accordance with the computer readable code to laser mark the work piece.
US08585955B2	Core assembly for an injection moulding-machine A core assembly for an injection molding-machine. The assembly includes a movable mold half and a stationary mold half clamped onto each their platen of an injection molding-machine. It also includes an actuator for advancing and retracting during operation at least one core into and from a mold cavity in a mold. The actuator is connected to a core-carrier for carrying the at least one core. The core-carrier is slidingly mounted to and partly projecting from a guidance connected to one of the mold halves. A first hole is formed in the closed mold for slidingly receiving the projecting part of the core-carrier. The core assembly allows products to be continuously molded with an extremely high degree of accuracy, and it is simple, inexpensive and easy to mount and maintain while also allowing for positioning of cores at various angles relative to the mold.
US08585953B2	Process for preparing tablet powder or poured cosmetic products A new process for preparing tablet powder or poured cosmetic products comprises preparing different cosmetic compounds in a slurry, i.e. “semi-liquids”, preparing a pre-molded container (1) equipped with separating partitions (2) of small height with respect to the total depth of the container (1) and pouring said cosmetic compounds (4) into respective spaces adjacent to the container (1) defined between said partitions (2). Pouring is performed so that at least one of said poured compounds surmounts all the partitions (2) of the container (1). The process continues with the solidification of the poured compounds until forming a unique cosmetic product (6) with adjacent tablets (4) corresponding to the different poured compounds, the extraction of said unique solidified product (6) from the container (1), and its insertion into a final package. The internal partitions (3) of the container (1) may be fixed to the bottom of the container (1) in a permanent or removable manner.
US08585952B2	Pressure molded preform process for composite structures A method of forming a composite elongated member is provided. The method includes forming a preform having at least one of a groove and a ridge. The at least one of a groove and a ridge extends a length of the preform. The preform is then shaped to create the elongated member having a desired cross-sectional shape with at least one curve formed along at least one of the at least one groove and ridge.
US08585948B2	Method and device for applying a reference mark on a rotor blade for a wind power plant A method, a device (20), an arrangement and a use for applying a reference mark on a rotor blade (1) for a wind power plant. After producing the rotor blade (1) in a manufacturing mold (34, 34′, 35) and before removing the rotor blade (1) from the manufacturing mold (34, 34′, 35), a reference mark is applied in the area of a rotor blade root (5) of the rotor blade (1) by means of a marking device (23), which is connected or can be connected to a holding device (21) disposed at a predetermined or predeterminable position on the manufacturing mold (34, 34′, 35).
US08585946B2	Method for making heat-insulative paper containers and the products A method for making heat-insulated paper containers and the products made by the same. The method includes steps of: (a) mixing and blending polyethylene terephthalate or polypropylene with an adhesive to form a polymer material; (b) heating and extruding the polymer material with an extruder machine to form a film and coating a surface of paper with the film; (c) cooling and laminating the paper with a laminating roller; (d) continuously coating another surface of the paper with a foam material; and then furling the paper after drying; and cutting the paper into a semi-product and then molding into a paper container; (e) heating the foam material with a heating device. The method can enhance the foam uniformity and the production rate, and decrease the defective rate.
US08585941B2	Structure with luminous and visual effects and light transmissive sheet thereof and method for making the same The present invention relates to a structure with luminous and visual effects, a light transmissive sheet thereof, and a method for making the same. The light transmissive sheet includes a first layer, a light transmissive intermediate layer and a second layer. The material of the first layer, the light transmissive intermediate layer and the second layer is polyurethane resin. The light transmissive intermediate layer is disposed on the first layer, and the second layer is disposed on the light transmissive intermediate layer. At least one pattern is formed on the first layer or the second layer, and the pattern penetrates the first layer or the second layer. When light irradiates the light transmissive sheet, the pattern is shown, so the light transmissive sheet has luminous and visual effects.
US08585936B2	Methods for photovoltaic absorbers with controlled group 11 stoichiometry This invention includes processes for making a photovoltaic absorber layer having a predetermined stoichiometry on a substrate by depositing a precursor having the predetermined stoichiometry onto the substrate and converting the deposited precursor into a photovoltaic absorber material. This invention further includes processes for making a photovoltaic absorber layer having a predetermined stoichiometry on a substrate by (a) providing a polymeric precursor having the predetermined stoichiometry; (b) providing a substrate; (c) depositing the precursor onto the substrate; and (d) heating the substrate.
US08585935B2	Composite for Li-ion cells and the preparation process thereof Disclosed herein is a composite for Li-ion cells, comprising an active material particle for Li-ion cells and an electronically conductive elastic material bound or attached to the active material particle. According to the present invention, the electronically conductive elastic material bound or attached to the active material particle allows the particle to maintain electronic contact with the electrode laminate matrix despite ongoing movement or expansion and contraction of the active material particles, such that the cycling efficiency and reversible capacity of the Li-ion cells prepared from the composite of the present invention is improved.
US08585930B2	Mono and bis-ester derivatives of pyridinium and quinolinium compounds as environmentally friendly corrosion inhibitors A quaternary nitrogen-containing corrosion inhibitor of formula wherein is an aromatic, nitrogen-containing ring of 5 to 14 ring atoms, optionally containing an additional N, O or S ring atom and optionally substituted with one or more alkyl, alkenyl, aryl, arylalkyl, cycloalkyl, amino, aminoalkyl, alkoxy, hydroxylalkyl, or cyano groups, or a mixture thereof; Y is a group of formula —OC(O)R1 or —C(O)R1; L is C1-C10 alkyl, C2-C10 alkenyl or a group of formula —CH2CH(OR2)CH2—; R1 is C8-C20 alkyl or C8-C20 alkenyl; R2 is H or —C(O)R1; R3 and R4 are independently selected from H, alkyl, alkenyl, amino, alkoxy, hydroxylalkyl and cyano; and X is Br, Cl or I is particularly useful for inhibiting corrosion in oil and gas field applications.
US08585922B2	Liquid-crystalline medium The invention relates to a liquid-crystalline medium comprising one or more compounds of the formula I in which R0, ring A and L1-4 have the meanings indicated in Claim 1, and to the use thereof in electro-optical liquid-crystal displays.
US08585921B2	Electrode material containing polyvinyl alcohol as binder and rechargeable lithium battery comprising the same Provided is an electrode mix for a secondary battery containing an electrode active material, comprising a PVA having a degree of polymerization of more than 2500 and a degree of saponification of more than 90% as a binder, and a lithium secondary battery comprising the same. Use of the binder according to the present invention can provide advantageous effects such as improved adhesive strength between the electrode mix and current collector and between the electrode mixes, prevention of the peeling and separation of the active material even after repeated charge/discharge cycles, and inhibition of decreases in the capacity or output power retention rate of the secondary battery.
US08585918B2	Method of etching a silicon-based material A method is described of selectively etching a silicon substrate in small local areas in order to form columns or pillars in the etched surface. The silicon substrate is held in an etching solution of hydrogen fluoride, a silver salt and an alcohol. The inclusion of the alcohol provides a greater packing density of the silicon columns.
US08585916B2	Micropores and methods of making and using thereof Disclosed herein are methods of making micropores of a desired height and/or width between two isotropic wet etched features in a substrate which comprises single-level isotropic wet etching the two features using an etchant and a mask distance that is less than 2× a set etch depth. Also disclosed herein are methods using the micropores and microfluidic devices comprising the micropores.
US08585914B2	Production method for vehicle window glass [Object] To provide a method for producing a vehicle window glass pane that possesses both a solar radiation energy blocking function and a radio wave transmitting function.[Means for achieving the Object] A method for producing a vehicle window glass pane on which an infrared reflective film is formed by a vacuum film forming method, which is characterized by having a process in which an edge portion of an infrared reflective film having a radio wave transmissible window produced by using a masking member is removed by dry etching, and further characterized in that the dry etching is carried out by using a grindstone or a laser.
US08585913B2	Printhead and method of forming same A printhead and a method of manufacturing a printhead are provided. The printhead includes a polymeric substrate including a surface. Portions of the polymeric substrate define a liquid chamber. A material layer is disposed on the surface of the polymeric substrate. Portions of the material layer define a nozzle bore. The nozzle bore is in fluid communication with the liquid chamber.
US08585911B2	Thin film antenna and the method of forming the same The present invention discloses a thin film multi-band antenna, which is formed by PVD-Roll to Roll process and is formed of metal-oxide, conductive polymer, conductive glue or CNT. In another aspect, the present invention discloses a manufacturing method of thin film antenna, comprising preparing gel, followed by coating the gel on a substrate to form a transparent thin film. Thermal process is performed to heat the thin film. The gel includes vinyl oxide and metal compounds, wherein the vinyl oxide includes PEO having In(NO)3.3H2O, In(Ac)3, SnCl2.2H2O, or Sn(C2O4) contained thereof.
US08585906B2	Regeneration of ion exchange resin and recovery of regenerant solution An apparatus and method for regenerating spent ion exchange resin is described. In one method, a fresh regenerant solution comprising sodium ions and chloride ions is prepared, and passed across spent cation exchange resin to regenerate the spent resin. To recover the spent regenerant solution, a regenerant treatment composition is added to the spent solution to form precipitate flocs, which are then separated out of the regenerant solution. The concentration of at least one of the sodium or chloride ions in the regenerant solution can also be adjusted to form fresh regenerant solution which can be reused.
US08585905B2	Devices, kits and methods for performing chemical processing Embodiment of the present invention features a device, method and kit for performing one or more processing steps on a sample. The device includes a housing and a processing component. The housing has a first vessel connector for receiving a first vessel and a second vessel connector for receiving a second vessel, and a passage, to provide fluid communication between the first and second vessels. The processing component is in fluid communication with the passage and for effecting a change in a fluid moving from the first vessel to the second vessel through the passage via centrifugal force.
US08585900B2	Compact upright bioreactor for the elimination of nutrients In accordance with particular process, method and system aspects there is provided a biological manner of treating water/wastewater. Treatment is undertaken in bioreactor configured to treat the water/wastewater through a first process of denitrification followed by a second process of biological phosphorus removal. The bioreactor may be defined by multiple stages arranged in compact vertical alignment, for example, to reduce a footprint of the bioreactor and to feed the water/wastewater between the stages using gravity. The stages may comprise, in order, a Deaeration stage, an Anoxic stage, an Anaerobic stage, and an Aerobic stage. Continuous vacuum operation in the Deaeration stage enhances the physical removal of oxygen and other dissolved gases.
US08585898B2	Scrapping device for a pressurised filtration plant The present invention relates to a pressurized filtration plant that includes: a sealed tank (1) in which discs (2) are provided including filtering sectors (20) carried by a rotary shaft (3) and connected to collectors within said shaft, a dispenser (10) enabling the egress of filtrates, the discharge of spinning air and the intake of blowing air for releasing the spun cakes, at least one duct for supplying a liquid laden with solid particles, at least one duct or discharging the filtrates, and a hopper (1b) for recovering the solid particles, characterized in that the discs (2) are vertically arranged so that the lower portion thereof is submerged in buckets (4) covered with deflectors (41) and including means for scrapping solid material deposits on the outer walls thereof.
US08585897B2	Cylindrical back washing purification apparatus A cylindrical back washing purification apparatus comprises a main body (1), a cylindrical through hole (2) transversely provided in the main body (1), a plunger (4) slidably connected in the axial direction arranged in the through hole (2), a feed channel (6) and a discharge channel (8) connected with the through hole (2) on the main body (1). The outer peripheral portion of the foreside of the plunger (4) is concaved inward to form an annular cavity (10) with the inner wall of the through hole (2), the annular cavity (10) is connected with the feed channel (6), a “L”-type hole (12) which is connected with the discharge channel (8) is provided on the plunger (4) from fore to back in the axial direction, filtering holes (14) for connecting the annular cavity (10) with the “L”-type hole (12) are opened on the concaved peripheral face of the plunger (4) in the radial direction, a detachable filter screen (15) is coupled with the concaved peripheral face of the plunger (4). A strip (3) contacting with the inner wall of the through hole (2) is arranged in the annular cavity (10) on the plunger (4) in the axial direction; on the outer surface of the plunger (4), a semicircular groove (16) is provided on both sides of the discharge channel (8).
US08585895B2	Transportable water treatment system and chlorinator A transportable water treatment system includes: a lower cage housing a water purifying apparatus, a middle cage housing a first water storage tank, and an upper cage housing a second water storage tank. The transportable water treatment system has a footprint approximate to the area of the lower cage. A chlorinator may be used in the water purifying apparatus that includes a bowl having an inlet at the bottom and an outlet on its side. A channel is around the inlet forcing fluid to flow to the top of the channel and over its edges. A flow diverter is positioned above the inlet adapted to transfer the flow of fluid to a substantially horizontal direction. A platform is positioned within the channel being adapted to position a single chlorine tablet within the channel. The lid is adapted for holding a plurality of chlorine tablets above the platform.
US08585888B2	Copper-based water oxidation catalysts Methods for electrolysis of water to oxygen gas are provided. The method utilizes dimeric copper cations in water at a basic pH. The cations are provided in the water by adding a complex in solid form with an appropriate anion, or through a “self-assembly” method whereby a copper salt and appropriate ligands are added to water adjusted to a basic pH. The cations decrease the overpotential of water electrolysis, thereby providing for efficient generations of oxygen gas using a catalyst formed from an abundant material (copper).
US08585887B2	Aluminum alloy member and method for manufacturing same An aluminum alloy member includes a main body including an aluminum alloy serving as a base material, and an electrolytic oxidation ceramic coating coated at a portion of a surface of the main body and including a most outer layer and an inner layer which is arranged close to the main body relative to the most outer layer, the inner layer in which an aluminum oxide is richer than the most outer layer, the most outer layer in which a volume of a titanium oxide or a total volume of the titanium oxide and a zirconium oxide is richer than the inner surface.
US08585885B2	Electrochemically deposited indium composites Electrochemically deposited indium composites are disclosed. The indium composites include indium metal or an alloy of indium with one or more ceramic materials. The indium composites have high bulk thermal conductivities. Articles containing the indium composites also are disclosed.
US08585877B2	Multi-step deposition control For providing control of two-step or a multi-step deposition process, a method and a corresponding deposition system is provided comprising providing a deposition process having at least two sub-processes employing different sets of process parameters, wherein each set of process parameters comprises at least one process parameter. The method comprises controllably generating an actual value for at least one first process parameter by taking into account at least one previous value of the respective first process parameter, wherein each first process parameter is a process parameter of said at least two sets of process parameters.
US08585876B2	Cylinder block plate processing apparatus and sealing mechanism of the same A cylinder block plate processing apparatus in which one end side of an inner peripheral surface of a cylinder of a cylinder block is sealed to circulate a process liquid to perform pre-plating or plating processing of the cylinder inner peripheral surface. The apparatus includes: an apparatus body having a workpiece mount table on which the cylinder block is placed; a workpiece holding tool that is provided on the workpiece mount table so as to be vertically movable; an electrode support member including an electrode cylinder mounted to the apparatus body; a processing solution supply member that supplies a processing solution to the electrode support member; an electrode operated by the electrode cylinder; a sealing jig provided to one end of the electrode; a driving mechanism that drives the sealing jig; and a control circuit that controls operations of the processing solution supply member and the driving mechanism.
US08585875B2	Substrate plating apparatus with multi-channel field programmable gate array A system for electroplating a substrate includes one or more controllers, with each controller having an FPGA with one or more output channels. A bulk power supply is connected to each controller. One or more transistors are associated with each output channel. An electroplating chamber has one or more electrodes, with each electrode connected to at least one output channel. The system may include a waveform capture and viewing circuit providing built-in process verification and diagnostic tools. The system may also have a throttle back mode which attempts to maintain proper anode current ratios by reducing setpoints of all anodes by the same percentage, if a fault condition causes a reduction in current to one of the anodes. Blackbox logging may also optionally be used for recording selected data values into a circular buffer having a selected amount of memory.
US08585873B2	Methods and apparatus for sputtering A method of sputtering with sputtering apparatus is for depositing a layer upon a substrate. The apparatus includes a sputter target with a face exposed to the substrate and a magnetron providing a magnetic field that moves relative to the target face. The speed of movement of the field is controlled such that the uniformity of the deposition on the substrate is enhanced. A particular method includes monitoring uniformity verses speed, selecting the speed that gives the preferred uniformity and controlling the field to the selected speed. The selected speed may vary over the life of the target, with increased speeds becoming desirable as the target thins.
US08585868B2	Pyrolysis reactor A device for pyrolysing biomass comprises: a reactor space; a first feed for biomass material connecting to the upper zone thereof; a second feed for heated heat carrier material connecting to the upper side of the reactor space; a first discharge for pyrolysis gas connecting to the upper zone of the reactor space at a distance from the first feed; and a second discharge for solid material, for instance carbon and heat carrier material, connecting to the underside of the reactor space. A substantial separation between the discharge flows of pyrolysis gas and solid material takes place predominantly under the influence of gravitational force, without interposing of a cyclone. The reactor space is modeled such that the direct flow from the first feed and the second feed to the first discharge is blocked. A mechanical mixer is present in the reactor space for the purpose of mixing the flow of biomass material with the flow of preheated heat carrier material.
US08585867B2	Process for ignition of biomass flash carbonization A low-energy input process for the pyrolytic conversion of biomass to charcoal or carbonized charcoal is provided. The biomass is sealed in a container, pressurized, then air is introduced at the proximal end of the container and released at the distal end of the container. The biomass is ignited by a heater at the distal end. The operation of the heater is halted after initial ignition and the biomass is allowed to continue to burn in a proximal-to-distal end airflow to finish the conversion.
US08585866B2	Wire for papermaking of microfibrous cellulose-containing sheet and method for producing microfibrous cellulose-containing sheet A wire for papermaking of a microfibrous cellulose-containing sheet includes a base that has water permeability and a porous coating layer that is provided on at least one surface of the base, wherein the porous coating layer contains a porous pigment, an adhesive and a hydrophobizing agent.
US08585861B2	Heat-resistant structural epoxy resins Epoxy adhesive compositions containing a rubber-modified epoxy resin contain a bisphenol. The bisphenol can be pre-reacted with the rubber-modified epoxy resin to advance the resin. The adhesives are resistant to thermal degradation as can occur in so-called “overbake” conditions, in which the adhesive is heated to high temperatures for prolonged periods of time. In addition, expanded microballoons are included in epoxy structural adhesives to promote a desired fracture mode.
US08585859B2	Attachment member with integral adhesive channel and method An attachment member including an integral adhesive channel and a method of adhering an attachment member to a substrate includes adhering the member to the substrate using a first adhesive attached to the member to form a gap between the substrate and a bonding surface of the member defined by a perimeter edge. The first adhesive may be a pressure sensitive adhesive. The member defines a channel including a first opening configured to receive a second adhesive, which may be a flowable adhesive. The channel includes a second opening in fluid communication with the bonding surface. After adhering the member to the substrate with the first adhesive, the flowable adhesive is dispensed through the channel and into the gap such that the dispensed flowable adhesive is contained in the gap within the perimeter edge of the bonding surface. The flowable adhesive forms a bond between the substrate and the member.
US08585857B2	Method and equipment for butt joining the ends of a flexible, heat-sealing laminate and laminate thus obtained A method for butt joining a band (W) of flexible material, heat-sealing on at least one side and pre-printed on the opposite side, the band (W) being unwound from a parent reel (10), cut longitudinally into strips (W1, W2) and rewound into reels or rolls (20), the method consisting in overlaying the tail edge (L1) of a finished parent reel on top of the leading edge (L2) of a new parent reel, so that the printing of the one coincides with that of the other, cutting the band transversely along a line (R) in the area of overlaying of the edges (L1, L2), removing the ends (E1, E2) trimmed from the edges (L1, L2) and heat sealing on the heat-sealing side of the band (W), along the cutting line (R), a strip of heat-sealing material (S).
US08585853B2	Layered manufacturing method and layered manufacturing device A layered manufacturing method for forming a desired three-dimensional object by using a powder as a raw material. The method forms a desired solid body, which is employed in a layered manufacturing device, including a stage member having stage surface; a transparent member having an optical window to cover the stage surface to form an enclosed region together with the stage surface; and an exhaust system for exhausting gasses in the enclosed region. The optical window is positioned at a vertical upper direction when the enclosed region is formed.
US08585846B2	Method and device for closing the tail end of a log of web material and log obtained To close the tail end (L) of the web material forming the log (R) there is provided mechanical ply-bonding between the tail end and a portion of the last turn of web material, preferably a portion forming a fold (F) projecting from the log.
US08585842B2	Method for manufacturing multilayer ceramic substrate and composite sheet A high-quality resistor pattern and conductor pattern is formed on an external surface of a multilayer ceramic substrate by an ink jet method. A composite sheet including a first ceramic green layer and a shrinkage-retardant layer is formed, and a resistor pattern and a conductor pattern are formed on the first ceramic green layer of the composite sheet by an ink jet method. Subsequently, a plurality of second ceramic green layers are stacked with the composite sheet such that the shrinkage-retardant layer of the composite sheet defines an outermost layer, thus forming a multilayer composite including an unfired multilayer ceramic substrate and the shrinkage-retardant layer. Then, the multilayer composite is fired, and the shrinkage-retardant layer is removed to obtain a sintered multilayer ceramic substrate.
US08585841B2	Systems and methods for chemical and/or mechanical remediation of nitro compounds and nitrate esters Systems and methods for chemoremediation or mechanical destruction of undetonated explosive materials. An explosive apparatus contains an explosive material in close proximity to a chemical reagent selected for its chemoremediative properties. A barrier is interposed between the explosive material and the chemical reagent to delay the chemoremediation of the explosive material. Alternatively a water expandable material may be incorporated into the explosive material, whereby upon exposure to moisture the water absorbing material will expand sufficiently to fragment the explosive material into initiation insensitive particles. Initiation insensitivity is achieved by incorporation of water, which acts as a desensitizing agent as well as fragmenting the explosive material into particles sufficiently small that they are below the critical diameter for explosive initiation. The present invention also relates to self-degradable, shaped explosive formulations, comprising an explosive material and a water expandable material.
US08585829B2	Soil resistant floor cleaner A cleaning composition includes a fatty acid salt constituting up to about 50% by weight of the composition, an anti-slip agent constituting up to about 20% by weight of the composition, a soil resistant agent constituting up to about 20% by weight of the composition and water. Methods of cleaning coated and uncoated surfaces, and particularly stone surfaces, are also provided.
US08585825B2	Acoustic assisted single wafer wet clean for semiconductor wafer process A method for cleaning a substrate is provided that includes applying a liquid medium to a surface of the substrate such that the liquid medium substantially covers a portion of the substrate that is being cleaned. One or more transducers are used to generate acoustic energy. The generated acoustic energy is applied to the substrate and the liquid medium meniscus such that the applied acoustic energy to the liquid medium prevents cavitation within the liquid medium. The acoustic energy applied to the substrate provides maximum acoustic wave displacement to acoustic waves introduced into the liquid medium. The acoustic energy introduced into the substrate and the liquid medium enables dislodging of the particle contaminant from the surface of the substrate. The dislodged particle contaminants become entrapped within the liquid medium and are carried away from the surface of the substrate by the liquid medium.
US08585822B2	Method for testing group III-nitride wafers and group III-nitride wafers with test data The present invention discloses a new testing method of group III-nitride wafers. By utilizing the ammonothermal method, GaN or other Group III-nitride wafers can be obtained by slicing the bulk GaN ingots. Since these wafers originate from the same ingot, these wafers have similar properties/qualities. Therefore, properties of wafers sliced from an ingot can be estimated from measurement data obtained from selected number of wafers sliced from the same ingot or an ingot before slicing. These estimated properties can be used for product certificate of untested wafers. This scheme can reduce a significant amount of time, labor and cost related to quality control.
US08585821B2	SiC epitaxial substrate and method for producing the same In one embodiment of the present invention, a monocrystal SiC epitaxial substrate is produced which includes a monocrystal SiC substrate; a buffer layer made of a first SiC epitaxial film formed on the monocrystal SiC substrate; and an active layer made of a second SiC epitaxial film formed on the buffer layer. The buffer layer is grown by heat-treating a set of the monocrystal SiC substrate, a carbon source plate, and a metal Si melt layer having a predetermined thickness and interposed between the monocrystal SiC substrate and the metal Si melt layer, so as to epitaxially grow monocrystal SiC on the monocrystal SiC substrate. The active layer is grown by epitaxially growing monocrystal SiC on the buffer layer by vapor phase growth method. This allows for production of a monocrystal SiC epitaxial substrate including a high-quality monocrystal SiC active layer being low in defects.
US08585815B2	Non-aqueous inkjet ink A non-aqueous inkjet ink comprises silica and Brilliant Carmine 6B. A peak area obtained at the time of measurement of an organic acid quantity of a water extract of Brilliant Carmine 6B by use of a capillary electrophoresis apparatus is selected within the range of 50 to 300 mABU*sec.
US08585814B2	Active ray curable ink-jet ink, image forming method and ink-jet recording apparatus using the same A active ray curable ink-jet ink includes a multifunctional acrylate or methacrylate of at least three functional groups, and the acrylate or the methacrylate has a partial structure of the following Formula (1) in an amount of 5-40 weight % based on the total weight of the active ray curable ink-jet ink: Formula (1) —(R—O—)n—, wherein R is an alkylene group, and n is an integer of at least three.
US08585813B2	Flame retardant composition for cotton articles Compositions useful for the flame retardant finishing of cotton articles or other cellulose materials are described. The compositions are obtainable by reacting a tetrakishydroxyalkylphosphonium (THP) salt with caprolactam and urea to form a condensation product and subsequently forming a condensate from excess THP salt and excess urea. The compositions endow cotton articles with flame retardant properties and a pleasantly soft hand coupled with good durability to laundering processes.
US08585811B2	Electroless nickel alloy plating bath and process for depositing thereof An aqueous nickel phosphorus tin alloy electroless plating bath and process for depositing a nickel phosphorus tin alloy onto a substrate, particularly an aluminum substrate for memory disk applications, wherein the nickel phosphorus tin alloy deposit provides enhanced thermal stability, as defined by the inhibition of crystallization and suppression of magnetization upon high temperature annealing when compared to typical NiP deposits.
US08585810B2	Apparatus for regenerating a carbon dioxide absorption solution Provided is an apparatus for regenerating a carbon dioxide absorption solution that regenerates an absorption solution for absorbing carbon dioxide contained in a combustion exhaust gas emitted during a combustion process of a vehicle, thereby reducing energy costs while simplifying its configuration. The apparatus includes a first storage tank for storing an absorption solution that contains absorbed CO2; a regeneration column for generating an absorption solution regenerated by heating the absorption solution to free/release CO2; a separation drum for separating the CO2 freed/released during the regeneration; a multi-stepped compressor for compressing the separated CO2; a heat exchanger for performing a heat exchange between the absorption solution discharged from the first storage tank and the CO2 compressed in the multi-stepped compressor; a temperature sensor for detecting temperature of the absorption solution after the heat exchange in the heat exchanger; and a flow meter for controlling a flow rate of the absorption solution passing through the heat exchanger according to the temperature of the absorption solution detected by the temperature sensor.
US08585809B2	Air dryer cartridge An air dryer cartridge 100 configured for use on both conventional air dryer systems having internal purge air valving and newer air dryer systems wherein at least some of the purge air valving is located in the cartridge. The air dryer cartridge 100 has a first connector 112 for mating with a corresponding connector of a conventional air dryer system, and a second connector 156 for mating with a corresponding connector of a newer-style air dryer system. When the cartridge 100 is installed on a conventional air dryer system, purge air valving 144/146 within the cartridge is deactivated causing the cartridge to act as a conventional air dryer cartridge. When the cartridge 100 is installed in a newer-style system, the purge air valving 144/166 within the cartridge is activated thus enabling the system to function as designed.
US08585808B2	Zinc oxide containing filter media and methods of forming the same Filter media that includes activated carbon particulates and zinc oxide particles disposed on surfaces of the activated carbon particulates. The zinc oxide particles have an average crystallite dimension that is not greater than about 50 nm.
US08585807B2	Low-cost method for fabricating palladium and palladium-alloy thin films on porous supports A process for forming a palladium or palladium alloy membrane on a ceramic surface by forming a pre-colloid mixture comprising a powder palladium source, carrier fluid, dispersant and a pore former and a binder. Ultrasonically agitating the precolloid mixture and applying to a substrate with an ultrasonic nozzle and heat curing the coating form a palladium-based membrane.
US08585805B2	Cyclonic air cleaner An air cleaner device for filtering intake air including a housing defining a chamber, a filter element disposed within the chamber, and a duct element having a passageway in fluid communication with the chamber. Further, the duct element extends along and downwardly from about a portion of the housing and further includes an inlet for drawing intake air into the chamber. The air cleaner having a base member in fluid communication with the chamber and an outlet, where the air drawn into the chamber is filtered by first and second filtering operations to obtain filtered air, with the first and the second filtering operations accomplished at least in part due to a cyclonic motion of the air and passage of the air through the filter element, respectively; and where the filtered air from the chamber of the housing is released through the outlet in the base member.
US08585804B2	Natural gas liquids recovery device and method A natural gas liquids (NGL) recovery system and method for separating NGLs from a feed gas is provided. The method includes receiving the feed gas; increasing a pressure of the feed gas by running the feed gas through a compressor connected to a gas turbine; diverting part of the feed gas from an output of the compressor and feeding the diverted part to a dryer; drying the diverted part to remove water and produce a dry gas; expanding the dry gas in a turbo-expander; separating the expanded gas into the NGL and fuel gas; and providing the fuel gas to the gas turbine as fuel without contamination.
US08585802B2	Carbon dioxide capture and liquefaction An energy-efficient method of recovering carbon dioxide (CO2) in a high-pressure liquid state from a high-pressure gas stream. The method includes cooling, condensing, and/or separating CO2 from a high-pressure gas stream in two or more separation zones and further purifying the resulting sub-critical pressure liquid CO2 streams in a third purification zone to thereby provide purified CO2. The purified liquid CO2 may be pumped to above the critical pressure for further utilization and/or sequestration for industrial or environmental purposes.
US08585799B2	Air pre-treatment device The present technology provides an air pre-treatment and monitoring device that includes an inlet port configured to receive an air flow and an outlet port configured to expel the air flow. The illustrative air pre-treatment device further includes a multiple-stage filter arranged between the inlet and outlet ports and that is configured to filter particles from the air flow.
US08585791B2	Method of producing nodular silica sol In producing nodular silica sol, a polymerized silicic acid solution with viscosity of silicic acid from 0.9 to 100 mPa·s is prepared by aging a silicic acid solution with pH from 1.0 to 7.0 and silica concentration from 0.05 to 3.0% by weight at a temperature from 1 to 98° C. Then, a seed liquid is prepared by adding an alkali to the polymerized solution to adjust the pH from 10 to 12.5 and heating the resultant mixture solution at a temperature from 50 to 150° C. According to necessity, an alkali is added to the obtained seed liquid to adjust the pH in from 9 to 12.5. Finally, a silicic acid solution or a highly purified silicic acid solution is dropped to the seed liquid at a temperature from 20 to 98° C. continuously or intermittently for building up.
US08585789B2	Methods for gasification of carbonaceous materials The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising: adding one or more carbonaceous materials, adding a molecular oxygen-containing gas, adding carbon dioxide gas and optionally adding water into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism.
US08585783B2	Natural dyeing method of fiber using an indigo plant Provided is a natural dyeing method of a fiber using an indigo plant. The natural dyeing method includes dissolving a water-soluble pigment present in leaves of the indigo plant in water to mix the water containing the water-soluble pigment with lime powder and air, concentrating the resulting mixture into an insoluble pigment, mixing the concentrated indigo plant dye with caustic soda to reduce the resulting mixture into a water-soluble pigment through microbial fermentation, immersing a fiber in the soluble indigo plant dye solution to dye the fiber, and bringing the dyed fiber into contact with air to convert the soluble indigo plant dye solution into the insoluble pigment again, thereby completing natural dyeing using the indigo plant. Therefore, the natural dyeing can be performed at a very fast dyeing rate, and the fiber can show excellent color fastness. Also, the fiber cannot be easily discolored by water or detergent, and can be useful in preventing water pollution or dermatitis.
US08585778B2	Cationic 6-aminoindolines, dyeing compositions containing them, processes and uses thereof The present invention relates to a cationic 6-aminoindoline of general formula (I), the addition salts thereof with an acid and the solvates thereof: the present invention is also directed towards a method for synthesizing this cationic 6-aminoindoline, the compositions, the uses, the hair dyeing methods and the devices using this cationic 6-aminoindoline.
US08585773B1	Method and devices for implantation of biologic constructs Methods and devices for prepping and delivering a biologic construct repair for shoulder and joint surgery into an arthroscopic workspace.
US08585771B2	Methods and devices to curb appetite and/or to reduce food intake The present invention relates to devices and methods of operating the devices that contribute to curbing appetite and/or reducing food intake. In some embodiments, the methods and devices of the present invention include as intestinal/duodenal insert comprising an elongated member with at least one flow reduction element that can cause the stimulation of one or more biological signals of satiety. Some embodiments of the inserted device are anchored at the duodenal site by an anchoring member residing in the stomach, other embodiments of the device are stabilized at a targeted site by appropriate dimensions of length as well as one or more angled portions of the device that correspond to angled portions of the targeted site in the dodenum. Embodiments of the device exert effects by virtue of physical presence, as well as by more active forms of intervention, including release of bioactive materials and electrical stimulation of neurons.
US08585770B2	Implant sleeve for cement hip stems An implant sleeve operable to center an implant at an implantation site. The implant sleeve includes a proximal end, a distal end, an annular sidewall, a mesh portion of the annular sidewall, and an interior area. The annular sidewall is between the proximal end and the distal end. The mesh portion defines a plurality of openings in the annular sidewall. The interior area is defined by the annular sidewall and is configured to receive a stem of the implant. A longitudinal axis of the implant sleeve extends along an axial center of the interior area. In response to force applied to the implant sleeve, the implant sleeve compresses and the mesh portion expands outward from the longitudinal axis.
US08585766B2	Endplate-preserving spinal implant with an integration plate having durable connectors An interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, and single vertical aperture, as well as an integration plate having a roughened surface topography on its top surface. The integration plate and implant body are joined together with a durable connection.
US08585758B2	Accommodating intraocular lenses An intraocular lens having a light-transmitting optic (32, 94a, 94b, 142, 216) comprised of a synthetic light-refractive material (40, 102) operably coupled with a flexible optic positioning member (34, 62, 74, 84, 100, 210) to refract light onto the retina in order to correct refractive errors in the eye (10). The refractive material has an index of refraction of from about 1.36 to 1.5 or higher. The optic positioning member (34, 62, 74, 84, 100, 210) is constructed of a flexible synthetic resin material such as polymethylmethacrylate and permits focusing upon objects located near to and far from the viewer. The optic (32, 94a, 94b, 142, 216) of the present invention possess greater refractive capability than optics conventionally used in IOL construction, and permits retinal receipt of the image being viewed in order to correct refractive errors.
US08585757B2	Support system for bioprosthetic valves with commisural posts with heart-shaped openings A novel support system for bioprosthetic cardiac valves with heart shape commissural posts (18) and intercommissural conjunctions with long openings with oval closures (8), allows the better function of the valve by diminishing the forces applied on the leaflets during the cardiac cycle.
US08585755B2	Prosthetic apparatus for implantation at mitral valve Embodiments of prosthetics configured for implanting in at the native mitral valve region of the heart include a main body that is radially compressible to a radially compressed state and self-expandable from the compressed state to a radially expanded state. The prosthetic apparatus also comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body with a leaflet-receiving space between the anchor and an outer surface of the main body to receive a native valve leaflet. Methods and apparatus for delivering and implanting the prosthetic valve are also described.
US08585754B2	Stent formed of a Biodegradable material A stent is fabricated utilizing a polymer that is selected for its tendency to degrade from the surface inwardly rather than undergo bulk erosion so as to substantially reduce the risk of large particles becoming detached and being swept downstream. Such polymer is hydrophobic yet has water-labile linkages interconnecting the monomers. Ester or imide bonds are incorporated in the polymer to render the surface degrading materials suitable for use in stent applications. The stent may be coated with such polymer or may be wholly formed therefrom.
US08585753B2	Fibrillated biodegradable prosthesis The present invention is a more durable expanded material that enables thinner wall thicknesses and a more flexible reinforcement suitable for stenting. The present invention is especially useful in the construction of grafts, stents, and stent-grafts which are used, for example, in repairing or replacing blood vessels that are narrowed or occluded by disease, aneurismal blood vessels, or other medical treatments. The inventive material and configurations allow expansion or contraction in size or adjustment in size in an incremental manner so that the optimum size, shape, and fit with other objects can be obtained. The present invention is also optionally capable of more accurately delivering one or more active ingredients such as drugs over longer periods of time. The present invention optionally includes surface modifications and additives that increase the surface adhesion of active ingredients, coatings, or combinations thereof. Finally, the present invention optionally includes growing cells on the inventive material so that the expanded material, reinforcement, or combinations thereof are useful, for example, in producing lab-grown blood vessels or organs.
US08585751B2	Intravascular hinge stent A balloon or self expandable endoprosthesis formed of a single or multiple joined stent sections. Each section has a node and strut structure extending throughout in order to uncouple expansion forces of the stent to hold a blood vessel outward from crush forces that resist the formation of an oval shape during crush deformation. The hinge can bend in the direction of a uniformly curved surface of the stent but not in the radial direction. The strut can bend in the radial direction but not in the uniformly curved surface of the stent. The widths, lengths, and radial dimensions of the hinges and struts provide a balloon-expandable hinge stent that is non-crushable. For a self-expanding stent the hinge and strut dimensions provide expansion forces that are controlled independently from crush forces. Expansion properties are determined by the hinge dimensions and crush properties are determined independently by strut dimensions.
US08585750B2	Retraction mechanism and method for graft cover retraction A stent or stent-graft delivery system includes a handle having a graft cover retractor having a screw gear and a drive and quick release assembly. The drive and quick release assembly allows a user to retract a graft cover by rotating the assembly in a first rotational direction about the screw gear. When the assembly is being rotated in a particular rotational direction, a partial revolution in the opposite rotational direction disengages the assembly from the screw gear, which is sensed by a change in the force required to rotate the assembly. With the assembly disengaged from the screw gear, the assembly can be slid along the screw so that the graft cover can be positioned more quickly. In transitioning from using the screw gear to sliding along screw gear, it unnecessary to push any button and unnecessary for the user to remove her/his hand from the assembly.
US08585749B2	Expansion-assisting delivery system for self-expanding stent A delivery system for a self-expanding stent includes a catheter having a distal end and being configured to retain a self-expanding stent proximate the distal end. The delivery system also includes an inflatable device provided on the catheter and positioned proximate the distal end. The inflatable device, typically a balloon, is configured to selectively assist the self-expanding stent with radial expansion. The catheter includes a tubular member and an outer member coaxially positioned about the tubular member. The outer member can slide relative to the tubular member in an axial direction. The outer member is configured to retain a self-expanding stent in a radially-compressed position and to release the self-expanding stent to a radially-expanded position.
US08585747B2	Devices and methods for controlling and indicating the length of an interventional element Devices and methods are provided for controlling and indicating the deployed length of an interventional element on an interventional catheter. The interventional element may be a stent or series of stents, a balloon, or any other interventional element for which length control is necessary or desirable. Devices for controlling the length of the interventional element include gear driven actuators, motors, and other mechanisms. Devices for indicating length of an interventional element to the user include sensors, detents, visual displays and other mechanisms providing visual, audible, and tangible indications of length to the user. The control and indication devices preferably work in tandem to enable highly precise adjustment of interventional element length.
US08585745B2	Tanning device and method therefor A tanning device has one or more reflective surface areas. The reflective surface areas may be used for redirecting light rays toward one or more parts of a user's body.
US08585742B2	Bone fixation device A bone fixation device (1) for internal fixation of bone fragments with a longitudinal axis (2) and comprising: A) a first and a second plate (3, 4) each having a lower surface (5), an upper surface (6), two lateral surfaces (22, 23), a front surface (7) axially intermediate between said first and second plate (3, 4), an axially terminal surface (8) and at least one screw hole (17) extending from said upper surface (6) to said lower surface (5) and intended to receive a bone screw; B) a first and a second guide rail (13, 14) arranged parallel with respect to said longitudinal axis (2) and uniaxially slideably connecting said first and second plate (3, 4); and C) at least one resilient member (15, 16) arranged between said first and second plate (3, 4) acting as a compression spring.
US08585733B2	Devices, tools and methods for performing minimally invasive abdominal surgical procedures Methods, systems, devices and assemblies are provided for treating a patient by: making an incision or puncture though the patient's skin over the abdominal cavity; establishing an initial tract through an opening formed by the incision or puncture; advancing an instrument through the tract; contacting a distal end portion of the instrument against an inner surface of the abdominal cavity; driving at least one stitching needle through the inner surface of the abdominal cavity; continuing the driving until the at least one stitching needle exits the inner surface of the abdominal cavity; anchoring a suture carried by each of the at least one stitching needle to a suture anchor at an exit location, respectively; and applying tension to each of the sutures.
US08585731B2	Self-expanding devices and methods therefor Described here are self-expanding devices and methods of using and making them. The devices may be useful in a variety of locations within the body, for a number of different uses. In some variations, the devices have a first compressed configuration enabling low profile delivery through a delivery device, a second expanded configuration for apposition against tissue, and comprise either a single continuous filament or at least two non-intersecting filaments. In some variations, the device is formed into a shape having a series of peaks and valleys. At least one of the peaks and valleys may have a loop at then end thereof. At least a portion of these devices may be capable of biodegrading over a predetermined period of time, and the devices may be configured for drug delivery. Methods of treating one or more sinus cavities are also described here.
US08585730B2	Self-expanding devices and methods therefor Described here are delivery devices for delivering one or more implants to the body, and methods of using. The delivery devices may deliver implants to a variety of locations within the body, for a number of different uses. In some variations, the delivery devices have a cannula with one or more curved sections. In some variations, a pusher may be used to release one or more implants from the cannula. In some variations, one or more of the released implants may be a self-expanding device. Methods of delivering implants to one or more sinus cavities are also described here.
US08585729B2	Method of dilating tissue of a sinus drainage pathway A method of treating a constricted sinus passageway of a patient includes traversing the canine fossa region of the patient so as to form a passageway in the sinus cavity. An elongate member is inserted through the passageway, the elongate member having an inflation member such as a balloon disposed thereon. The inflation member is positioned within the constricted passageway. The inflation member is expanded so as to expand at least a portion of the constricted sinus passageway.
US08585728B2	Method for accessing a sinus cavity and related anatomical features A method of confirming the location of an elongate member configured for placement within a patient's sinus cavity comprises introducing the elongate member through a nasal passageway to place a distal tip of the elongate member in a test position, the elongate member configured to emit illuminating light via the distal end of the elongate member. The location of the light is then viewed through the patient's skin to confirm the positioning of the elongate member.
US08585726B2	Surgical disc removal tool The disclosure provides a tissue removal device including customizable tips. The tissue removal device may include an outer shaft and a threaded shaft. One aspect of disclosure may include a shaft cutting tool that emerges from the end of the outer shaft. Another aspect of the disclosure may include a flexible cutting blade extending from the threaded shaft. Threaded shaft may be driven by a driving mechanism in order to provide an auger-like suction mechanism to facilitate the transfer of removed tissue to a collection chamber that is coupled to the outer shaft and the threaded shaft.
US08585725B2	Laparoscopic scalpel and method for use A laparoscopic scalpel includes a shaft and a recess disposed in a surface of the shaft proximal to a distal end of the shaft. A blade is attached to the shaft. The blade includes a cutting edge having a portion exposed by the recess and oriented outwardly from the recess. A proximal end of the portion of the cutting edge exposed by the recess is disposed further from the surface than is a distal end of the portion of the cutting edge exposed by the recess.
US08585723B2	Coil anchor systems and methods of use Vessel occlusion method including the steps of positioning a coil anchor in a large diameter blood vessel, wherein the coil anchor includes a radially expandable sidewall, a proximal opening dimensioned to receive an embolic coil, a distal opening, and the coil anchor further comprising at least one coil retaining element configured to retain an embolic coil within the blood vessel. The vessel occlusion method further including the steps of expanding the coil anchor within the blood vessel; and delivering at least one embolic coil into the blood vessel, wherein the retaining element prevents the at least one embolic coil from migrating downstream of the coil anchor.
US08585722B2	System and method for attaching a vein, an artery, or a tube in a vascular environment A device for assisting in a vascular procedure is provided that includes a handle and one or more legs that are operable to move in response to a force being applied to the handle. The legs are operable to extend and to contract in order to manipulate a conduit. In a more particular embodiment, the device can be used in conjunction with a stand operable to receive the conduit such that the conduit can be removed from the stand by the device. The stand may include one or more graduations that indicate the size of the conduit once it is positioned on the stand.
US08585720B2	Suture trimmer In accordance with the present invention there is provided a suture trimmer, the suture trimmer comprising a shaft having a proximal end and a distal end and an axis therebetween, the shaft having a groove formed in the side thereof, the groove in communication with an opening formed in the side of the shaft, the opening disposed proximal the distal end. The suture trimmer further including a cutting member slidably disposed within the shaft, and a suture retainer slidably disposed within the shaft. Wherein the suture trimmer in accordance with the present invention may be additionally utilized to position knots formed within a suture loop prior to trimming the free end(s) of the suture loop.
US08585713B2	Expandable tip assembly for thrombus management Systems, methods, and devices for the treatment of acute ischemic stroke that provide immediate blood flow restoration to a vessel occluded by a clot and, after reestablishing blood flow, address the clot itself. Immediate blood flow restoration advantageously can facilitate natural lysis of the clot and also can reduce or obviate the concern for distal embolization due to fragmentation of the clot. Several embodiments of the invention provide for progressive, or modular, treatment based upon the nature of the clot. For example, the progressive treatment can include immediate restoration of blood flow, in-situ clot management, and/or clot removal depending on the particular circumstances of the treatment. The in-situ clot management can include, for example, lysis, maceration, and/or removal.
US08585711B2	Instrumentation for recording and replicating orthopaedic implant orientation An instrument for recording and replicating the spatial orientation of a dialable component of an implant relative to a bone engaging component of the implant includes a base assembly configured to support the trial implant so that the datum is in a predetermined orientation, a fixture supported on said base assembly, said fixture including an alignment tool configured to engage the first dialable component of the trial implant when the trial implant is supported by said base assembly, and a locking assembly configured to record the angular orientation of said alignment tool relative to said fixture with said alignment tool engaged with the first dialable component, and to replicate the recorded angular orientation with the alignment tool and a second dialable component.
US08585709B2	Straight cup impactor with lever arm An orthopedic impactor device for positioning an orthopedic prosthetic cup implant during a hip replacement surgery is described. The impactor is designed with a “one piece” elongated body portion, having a distal prosthetic cup engagement portion which is separated from a proximal strike plate by an annular sidewall. A handle portion is positioned circumferentially around the annular sidewall of the elongated body in a slidable relationship along a longitudinal axis. A rod, connectable to an orthopedic prosthetic cup, is positioned within a cavity of the body and connected to the proximal ring. A lever arm having a distal wedge portion is pivotally connected to the handle portion such that when the lever arm is pivoted towards the annular sidewall of the handle portion, the distal end of the rod moves within the body cavity.
US08585708B2	Patient selectable joint arthroplasty devices and surgical tools A patellar 3-D guidance tool includes a template. The template includes at least one contact surface for engaging a surface of the patella. The at least one contact surface substantially conforms with the surface associated with the patellar. At least one guide aperture directs movement of a surgical instrument, wherein the shape and/or position of the guide aperture is based, at least in part, on three or more anatomic reference points associated with the patellar.

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