最新美国发明专利第2013-11-12期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US08580962B2	Spiroheterocyclic compounds as mGlu5 antagonists The invention is directed to methods of using antagonists selective for the metabotropic mGlu5 receptor to treat conditions of neuromuscular dysfunction of the lower urinary tract in a mammal. Provided are methods of treating a mammal suffering from a condition of neuromuscular dysfunction of the lower urinary tract by administering a selective mGlu5 antagonist. The selective mGlu5 antagonist may be administered alone or in combination with one or more additional therapeutic agents for treating such a condition. Also provided are methods of identifying selective mGlu5 antagonists that are useful for treating neuromuscular dysfunction of the lower urinary tract in a mammal. Methods for treating migraine and gastroesophageal reflux disease (GERD) using selective mGlu5 antagonists are also disclosed.
US08580952B2	Glyoxal free purified cationic polygalactomannan A glyoxal and boron free purified cationic polygalactomannan may be prepared by reacting a polygalactomannan flour, a nonionically derivatized polygalactomannan flour, or a mixture thereof, with a cationising reagent, adjusting the pH to be from about 4 to about 6; cross-linking the cationic with glyoxal, and filtering and water washing the cationic polygalactomannan to produce a glyoxalated purified cationic polygalactomannan containing not more than 70% by weight of water. In some cases it may be desirable to introduce a buffering agent to the glyoxalated purified cationic polygalactomannan to regulate the pH to from 8.0 to about 9.5, when measured at 1% (dry matter) in water. In other cases, it may be desirable to remove water to produce glyoxal free purified cationic polygalactomannan in powder form. Such compounds are particularly useful in personal care products.
US08580951B2	Aldehyde-functionalized polysaccharides Novel aldehyde-functionalized polysaccharide compositions are described that are more stable in aqueous solution than oxidized polysaccharides or other types of polysaccharides containing pendant aldehyde groups. The aldehyde-functionalized polysaccharides may be reacted with various amine-containing polymers to form hydrogel tissue adhesives and sealants that may be useful for medical applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, preventing leakage of fluids such as blood, bile, gastrointestinal fluid and cerebrospinal fluid, ophthalmic procedures, drug delivery, and preventing post-surgical adhesions.
US08580950B2	Aldehyde-functionalized polysaccharides Novel aldehyde-functionalized polysaccharide compositions containing pendant dialdehyde groups are described that are more stable in aqueous solution than oxidized polysaccharides. The aldehyde-functionalized polysaccharides may be reacted with various amine-containing polymers to form hydrogel tissue adhesives and sealants that may be useful for medical applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, preventing leakage of fluids such as blood, bile, gastrointestinal fluid and cerebrospinal fluid, ophthalmic procedures, drug delivery, and preventing post-surgical adhesions.
US08580944B2	Suppressors of CpG oligonucleotides and methods of use The present disclosure relates to oligodeoxynucleotides that suppress an immune response. Methods are disclosed for preventing or treating an immune-mediated disorder, such as, but not limited to, an autoimmune disease, by administering a therapeutically effective amount of a suppressive oligodeoxynucleotide. Also disclosed are methods of suppressing an immune response in a subject by administering a therapeutically effective amount of a suppressive oligodeoxynucleotide.
US08580942B2	Plant regulatory elements from a metallothionein-like gene and uses thereof The present invention provides novel regulatory elements for use in plants. The present invention also provides DNA constructs containing these novel regulatory elements; transgenic cells, plants, and seeds containing these novel regulatory elements; and methods for preparing and using the same.
US08580940B2	Photoporphyrinogen oxidase having activity of imparting resistance against acifluorfen and gene thereof Protoporphyrinogen oxidase having an activity of imparting acifluorfen resistance and gene thereof are provided. Cyanobacterium protoporphyrinogen oxidase gene is identified by introducing a protoporphyrinogen oxidase gene of Arabidopsis into cyanobacterium, disrupting a cyanobacterium gene with a transposon, selecting a mutant strain in which protoporphyrinogen oxidase gene is disrupted, identifying the disrupted protoporphyrinogen oxidase gene, and isolating the disrupted protoporphyrinogen oxidase gene. This procedure is effective as a gene isolation technique when a protein derived from other organism species that is homologous to a known protein (e.g., protoporphyrinogen oxidase from cyanobacterium) can not be found in a gene database of the other species.
US08580935B2	Ultra-fast chromatography The present invention relates to a chromatographic method of separating biological material comprising, providing chromatographic media comprising inorganic oxide particles having an average diameter of about 2 microns or less and an average pore diameter of 300 Å or more; applying a solvent comprising said biological material to said media, wherein said biological material is reversibly bonded to said media; and eluting said biological material from said media with a solvent in less than about 2 minutes for biological material having a molecular weight of less than about 100,000 Daltons.
US08580934B2	Silica-based material for detection and isolation of chitin and chitin-containing microorganisms The subject invention provides silica-based material that has high affinity to chitin, chitin derivatives and chitin-containing microorganisms at an acidic pH. In an embodiment, the silica-based material surface comprises glass. Also provided are methods for preparing the subject silica-based chitin-binding material. In addition, the subject invention provides rapid, specific, sensitive, accurate and convenient methods for detection, isolation and purification of chitin, chitin derivatives and chitin-containing microorganisms.
US08580932B2	Method of thermostabilization of a protein and/or stabilization towards organic solvents Thermostabilization of a protein where the protein contains access routes and wherein at least one amino acid in the bottleneck of the access route is mutated, includes identifying the amino acids of the bottleneck and the amino acids control exchange of the solvent between a buried protein core and surrounding environment and/or in the packing of the amino acids inside the access route. Modification of the amino acids are determined so that the packing of the amino acids inside the tunnel is improved and the access route prevents access of undesired solvent molecules to the protein core, while allowing passage of the compounds necessary at the protein core to enable the protein to perform its biological function.
US08580923B2	Self-assembling peptide amphiphiles and related methods for growth factor delivery Amphiphilic peptide compounds comprising one or more epitope sequences for binding interaction with one or more corresponding growth factors, micellar assemblies of such compounds and related methods of use.
US08580922B2	Peptide linkers for polypeptide compositions and methods for using same Disclosed herein are novel peptide linkers and polypeptide compositions comprising the linkers (e.g., chimeric polypeptides) and methods of using the polypeptide compositions. The compositions and methods are particularly useful for targeting/delivering a polypeptide or protein of interest (e.g., a therapeutic polypeptide) to a cell, tissue or organ of interest in order to treat various diseases or disorders (e.g., lysosomal storage disorders).
US08580919B2	Polymer conjugates of GLP-1 Conjugates of a GLP-1 moiety may be covalently attached to one or more water-soluble polymers. For instance, a GLP-1 polymer conjugate may include a GLP-1 moiety releasably attached at its N-terminus to a water-soluble polymer. The GLP-1 polymer conjugate may include a GLP-1 moiety covalently attached to a water-soluble polymer, wherein the GLP-1 moiety possesses an N-methyl substituent.
US08580918B2	Peptidic GLP-2 agonists Novel GLP-2 analogs with improved pharmacokinetic properties are described as well as their use in the treatment of disease.
US08580914B2	Process for producing aliphatic polyester A process for producing an aliphatic polyester through ring-opening polymerization of a cyclic ester, wherein a partial polymer in a molten state is continuously introduced into a twin-screw stirring device to continuously obtain a partial polymer in a solid pulverized state, the partial polymer is subjected to solid-phase polymerization, and the resultant polymer is melt-kneaded together with a thermal stabilizer to be formed into pellets. As a result, an aliphatic polyester of a high molecular weight and with little discoloration is produced efficiently.
US08580910B2	2,4,5-triaminophenols and related compounds New triaminophenol compositions and related compounds are disclosed, as are processes for their preparation and for the preparation of novel salts and diacid complexes from such compounds. Polymers prepared from these compositions can be made into high strength fiber, film, and tape and are useful in applications such as protective apparel, aircraft, automotive components, personal electronics, and sports equipment.
US08580908B2	Method and chemical composition for reclaiming of cured elastomer materials Reclaiming cured elastomer material by mixing the cured elastomer as crumbs or chips with a devulcanization-aiding chemical composition, and devulcanizing the cured material by applying a shear-stress deformation to the mixture of the crumbs or chips with a devulcanization-aiding chemical while performing a mechanical disintegration of the cured elastomer into fine-ground crumbs under controllable temperature not exceeding about 90 degrees C., where the chemical composition includes a first agent promoting scission of sulfide bonds of free radicals formed under the shear-stress deformation, which is selected from amines and sulfides and their derivatives, a second agent providing the pre-set acidity during the process inhibiting recombination of sulfide bonds, which is selected from organic acids and their anhydrides, a third agent contributing to fast stabilization of the free radicals, which is selected from oxidants, and a fourth agent promoting redox reaction, which is selected from oxides of metals with variable valence.
US08580906B2	Polyrotaxane, aqueous polyrotaxane dispersion composition, crosslinked body of polyrotaxane and polymer and method for producing the same Provided are a polyrotaxane capable of using an aqueous solvent in a fabricating process although it has hydrophobicity, an aqueous composition having the polyrotaxane, a crosslinked body comprising the polyrotaxane, etc. The polyrotaxane comprises blocking groups located at both ends of a pseudo-polyrotaxane having cyclic molecules and a linear molecule which pierces the cavities of the cyclic molecules in a skewered manner to form a clathrate therewith so as not to detach the cyclic molecules, wherein the cyclic molecules have a group represented by Formula I, a group represented by Formula II and a group represented by Formula III. Incidentally, M represents, for example, a group derived from ring-opening polymerization of ε-caprolactone or the like, A represents a hydroxy group or the like, B represents a —COOH group or the like, and C represents A and/or B: -M-A Formula I; -M-B Formula II; and —C Formula III.
US08580905B2	Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants The present invention relates to a polymeric material comprising units capable of having a cationic charge at a pH of from about 4 to about 12; provided that said polymeric material has an average cationic charge density from about 2.75 or less units per 100 daltons molecular weight at a pH of from about 4 to about 12. The polymeric material is a suds enhancer and a suds volume extender for hand dishwashing compositions and personal care products such as soaps, shaving cream foam, foaming shaving gel, foam dephiliatories and shampoos. The polymers are also effective as a soil release agent in fabric cleaning compositions. The polymers are also useful in agrochemical foam, fire-fighting foam, hard surface cleaner foam, and coagulant for titanium dioxide in paper making.
US08580899B2	Process for producing moldings with an increase in the melt stiffness A process for producing moldings with condensing-up of a polyamide molding composition by means of a compound having at least two carbonate units, wherein a) a polyamide molding composition is made available, b) a mixture of the polyamide molding composition and the compound having at least two carbonate units is prepared, c) the mixture is, if appropriate, stored and/or transported and d) the mixture is subsequently processed to produce the molding, with the condensing-up occurring only in this step, and the molding is a hollow body or hollow profile having an external diameter of at least 30 mm and a wall thickness of at least 1 mm, effects a significant increase in the melt stiffness combined with moderate processing presssures, which considerably simplifies the production of these moldings.
US08580898B2	Copolymer polyester resin and molded product using same The present invention relates to a copolymer polyester resin and a molded product using the same, and more specifically to a copolymer polyester resin that contains 10˜80 mol % of 1,4-cyclohexane dimethanol, 0.1˜50 mol % of a diol compound expressed as HO—(CH2)a—CO—(CH2)b—OH (where a and b are integers in the range 1˜5), and ethylene glycol or other diols so that the sum of its entire diol composition is 100 mol % based on dicarboxylic acid. The copolymer polyester resin of the present invention enables reduction of cycle time, improvement of product processability and prevention of PET bottle deformation during mold processing with a heat-shrinking label by complementing low temperature shrinkage, maintaining a high shrinkage rate, and reducing shrinkage stress.
US08580896B2	Process for preparing fluorine-containing polymer A process for preparing a fluorine-containing polymer which includes a first step for preparing a dispersion of fluorine-containing emulsified particles (A) having ionic functional groups where a fluorine-containing monomer mixture (i) is polymerized by using a water soluble radical polymerization initiator (a) without addition of an emulsifying agent, and a second step for preparing a fluorine-containing polymer (b) having a small amount of ionic functional groups where fluorine-containing monomers (ii) are emulsion-polymerized by using a radical polymerization initiator (b) in the presence of the fluorine-containing emulsified particles (A) having ionic functional groups without addition of an emulsifying agent.
US08580894B2	Two part, low molecular weight self curing, low viscosity acrylic penetrant, sealant and coating composition, and methods for using the same A self curing, two component penetrating densifying sealant and coating composition that imparts protection and reinforcement to porous substrates, such as wood and concrete, as well as non porous substrates, such a metal surfaces, whether or not corroded, and concrete surfaces.
US08580893B2	Methods for improving multimodal polyethylene and films produced therefrom A blown film composition including a first high density polyethylene component and a second high density polyethylene component, wherein the blown film contains a mixture of three or more discrete molecular weight distributions, and wherein the second high density polyethylene component has at least one more discrete molecular weight distribution than the first high density polyethylene component.
US08580892B2	Rubber composition and uses thereof A rubber composition has sufficient resistance to degradation and swelling caused by a liquid such as a water-soluble coolant and also is capable of having sufficient resistance to ozone. The rubber composition contains a fluororubber not having a vinylidene fluoride structure, a nitrile rubber, a fluorine-based oil and a peroxide vulcanizing agent.
US08580889B2	Addition curable self-adhesive silicone rubber composition An addition curable self-adhesive silicone rubber composition comprising (A) an organopolysiloxane containing at least two alkenyl groups, (B) an organohydrogenpolysiloxane containing at least three SiH groups, (C) another organohydrogenpolysiloxane containing no other reactive groups than SiH groups, and (F) an addition reaction catalyst, with a SiH/alkenyl molar ratio ranging from 0.8 to 5.0, is briefly moldable and cures to various metals and organic resins.
US08580885B2	Rubber composition and pneumatic tire using the same This invention provides a rubber composition highly balancing flexibility at a low temperature and a low rolling resistance, which is formed by compounding a low-molecular weight conjugated diene-based polymer (B) having at least one functional group, an aromatic vinyl compound content of less than 5% by mass and a weight average molecular weight as measured without terminating by modification through a gel permeation chromatography and converted to polystyrene of not less than 2,000 but less than 150,000 and a filler (C) into a high-molecular weight rubber component (A) having a weight average molecular weight as measured without terminating by modification through a gel permeation chromatography and converted to polystyrene of not less than 150,000.
US08580884B2	Thermoplastic polyurethane block copolymer compositions A novel block copolymer composition including a hydrogenated block copolymer that has at least one block A and at least one block B, and wherein (a) prior to hydrogenation each A block is a mono alkenyl arene homopolymer block and each B block is a controlled distribution copolymer block of at least one conjugated diene and at least one mono alkenyl arene, (b) subsequent to hydrogenation about 0-10% of the arene double bonds have been reduced, and at least about 90% of the conjugated diene double bonds have been reduced, (c) each A block having a number average molecular weight between about 3,000 and about 60,000 and each B block having a number average molecular weight between about 30,000 and about 300,000, (d) each B block comprises terminal regions adjacent to the A blocks that are rich in conjugated diene units and one or more regions not adjacent to the A blocks that are rich in mono alkenyl arene units, (e) the total amount of mono alkenyl arene in the hydrogenated block copolymer is about 5 percent weight to about 50 percent weight, and (f) the weight percent of mono alkenyl arene in each B block is between about 10 percent and about 75 percent. The thermoplastic polyurethane elastomer is present in the block copolymer in an amount from about 50 to about 95 percent by weight of a thermoplastic polyurethane elastomer.
US08580883B2	Latex binders, aqueous coatings and paints having freeze-thaw stability and methods for using same Disclosed are latex polymers and an aqueous coating compositions having excellent freeze-thaw stability, open time, stain resistance, low temperature film formation, foam resistance, block resistance, adhesion, water sensitivity and a low-VOC content. The latex polymers and aqueous coating compositions include at least one latex polymer derived from at least one monomer copolymerized or blended with an alkoxylated compound, for example an alkoxylated tristyrylphenol or an alkoxylated tributylphenol. Also provided is an aqueous coating composition including at least one latex polymer, at least one pigment, water and at least one freeze-thaw additive.
US08580881B2	Coating compositions Silicon nitride coated crucibles for holding melted semiconductor material and for use in preparing multicrystalline silicon ingots by a directional solidification process; methods for coating crucibles; methods for preparing silicon ingots and wafers; compositions for coating crucibles and silicon ingots and wafers with a low oxygen content.
US08580880B2	Method for stabilising liquid mercury using sulfur polymer cement, via mercury sulfide The invention relates to a method for stabilizing liquid mercury using sulfur polymer cement, via mercury sulfide. The method for stabilizing liquid mercury by the production of sulfur polymer cement comprises (a) transformation of the liquid mercury into mercury sulfide (metacinnabar) by a chemical reaction, under stoichiometric conditions, between mercury and elemental sulfur; and (b) production of sulfur polymer cement by incorporating the mercury sulfide produced in the previous step into a stable mixture consisting of aggregates, elemental sulfur and sulfur polymer.
US08580877B2	Construction comprising tie layer A vulcanizable layered composition comprising at least two layers and at least one tie layer, wherein the first layer of the two layers is a fluid permeation prevention layer preferably comprising: (A) at least one thermoplastic engineering component and (B) at least one elastomer component; the second layer of the two layers comprises at least one high diene rubber and the tie layer comprises a mixture of: (1) at least one halogenated isobutylene containing elastomer; (2) up to 50 weight % of at least one high diene elastomer; (3) at least one filler; (4) up to 30 weight % of at least one processing oil; (5) at least one tackifier; and (6) a curing system for the elastomers.
US08580876B2	Encapsulated phenolic antioxidants The present invention pertains to a concentrated aqueous polymer dispersion with an average particle size of less than 1000 nm comprising a polymer carrier, a non-polar organic phenolic antioxidant and a surfactant. The present invention also pertains to a process for the preparation of said concentrated aqueous polymer dispersion, to a polymer powder obtainable from said concentrated aqueous polymer dispersion, to a composition comprising an organic material and said concentrated aqueous polymer dispersion or said polymer powder and to the use of said concentrated aqueous polymer dispersion or said polymer powder as stabilizer for organic material.
US08580874B2	Polymer-modified asphalt compositions A modified-asphalt composition prepared by introducing a diene end-capped block copolymer with a molten asphalt composition.
US08580873B2	Aqueous dispersion comprising a (meth)acrylic polymer and a vinyl acetate polymer The present invention relates to an aqueous dispersion comprising (a) at least one (meth)acrylic polymer; (b) at least one vinyl acetate polymer selected from vinyl acetate homopolymer and vinyl acetate copolymers comprising in polymerized form vinyl acetate and ethylene; (c) water; and (d) optionally up to 50% by weight of an inorganic filler, based on the total weight of the aqueous dispersion, wherein the weight ratio of (meth)acrylic polymer(s) (a) to vinyl acetate polymer(s) (b) is from 70:30 to 30:70. The aqueous dispersion may be used as a joint compound or sealing compound.
US08580872B2	Sulfopolyester polymer compositions with improved water dispersibility A sulfopolyester containing residues of 2,2,4,4-tetralkylcyclobutane-1,3-diol such as 2,2,4,4-tetramethylcyclobutane-1,3-diol is highly dispersible in water. This allows one to reduce the content of sulfonate groups or reduce the amount of ethylene glycol or other hydrophilic glycols to retain good water resistance in cured coatings. The sulfopolyester may also be a reaction product of a 2,2,4,4-tetralkylcyclobutane-1,3-diol along with 1,4-cyclohexanedimethanol, neopentyl glycol, or a mixture thereof with an acid component. Coating compositions may also contain these sulfopolyesters along with water and a polymer resin.
US08580865B2	Phase-and sedimentation-stable, plastically deformable preparation with intrinsic pore forming, intended for example for filling bone defects or for use as bone substitute material, and method of producing it The invention relates to a phase and sedimentation-stable, plastically deformable preparation with intrinsic pore formation that can be used for instance for filling bone defects and for augmentation, and also relates to a method for producing same. The object of the invention, to provide a phase and sedimentation-stable, plastically deformable implant material with intrinsic pore formation, that is not complex to create, and that can be inserted into a bone defect by injection or alternatively can be applied to/fitted in a bone defect as a kneadable mass, is attained in that a plastically deformable preparation for bone construction/replacement based on ceramic suspension includes a particulate, porous component that is not easily soluble in water and at least one liquid, wax-like, or gel component that is dissolved in water or alcohol, the component that is not easily soluble in water being 60-98% by weight and the composition dissolved in water or alcohol being 1-30% by weight, the particles of the particulate component having a diameter in a size range that is essentially greater than a phagocytabler particle and smaller than the passage diameter of standard injection cannulas and the portion of the dissolved component in the water or alcohol being 0.1-3% by weight.
US08580859B2	Methionine analogs and methods of using same Provided are methionine analogs which may be useful for inhibiting protein synthesis, inhibiting microbial growth and/or treating infectious diseases. In some instances, the analogs exhibit bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and/or antiviral properties. Also provided are methods of treatment and methods of preparation, as well as kits and unit dosages.
US08580858B2	Compositions for the treatment of CNS-related conditions The invention provides compositions comprising extended release memantine in combination with immediate release donepezil to a subject. Memantine in an extended release form containing 22.5 to 30 mg memantine or a pharmaceutically acceptable salt thereof in combination with donepezil achieves particular pharmacokinetic criteria such as change in plasma concentration of memantine over time and ratio of maximum memantine plasma concentration to mean memantine plasma concentration.
US08580855B2	Acetaminophen / ibuprofen combinations and method for their use A pharmaceutical dosage form is provided comprising a non-steroidal anti-inflammatory agent and acetaminophen, and methods for their use. In one embodiment, the dosage form is comprised of ibuprofen and acetaminophen as the sole pharmaceutically effective agents, wherein the ibuprofen and acetaminophen are in a weight ratio of about 12 parts:about 88 parts.
US08580854B2	Methods of suppression of rage gene expression and rage triggered inflammatory genes by selected age-inhibitors Accelerated formation of advanced glycation/lipoxidation end products (AGEs/ALEs) has been implicated in the pathogenesis of various diabetic complications. Several natural and synthetic compounds have been proposed and tested as inhibitors of AGE/ALE formation. We have previously reported the therapeutic effects of several new AGE/ALE inhibitors on the prevention of nephropathy and dyslipidemia in streptozotocin (STZ)-induced diabetic rats. In this study, we investigated the effects of various concentrations of LR-90 on the progression of renal disease and its effects on AGE and receptor for AGE (RAGE) protein expression on the kidneys of diabetic STZ-rats. In vitro studies were also performed to determine if LR-90 could inhibit the expression of various pro-inflammatory mediators in human monocytic cells.
US08580853B2	Analgesic composition and method of making the same A soluble aspirin composition, comprising: (i) granules including aspirin, heat-treated bicarbonate salt, pharmaceutically-acceptable resin and surfactant, in mixture with: (ii) crystalline particles of pharmaceutically-acceptable acid; and (iii) crystalline particles of heat-treated bicarbonate salt; wherein the soluble aspirin composition when introduced to water undergoes reaction of the crystalline particles of pharmaceutically-acceptable acid with the heat-treated bicarbonate salt and the aspirin to effect effervescing action and disintegration of the granules with conversion of the aspirin to an acetylsalicylate compound of the bicarbonate salt cation so that the composition rapidly dissolves in the water without occurrence of undissolved residue. The composition is solublizable within 30 seconds in cool to cold water to provide an effervescent analgesic solution that can be readily orally administered to an individual in need of analgesia.
US08580849B2	Hydrous gel and production process and use of the hydrous gel A hydrous gel substantially comprising at least two polymers selected from the group consisting of polyacrylic acid, sodium polyacrylate and partially neutralized polyacrylate, and water, the polymers being crosslinked by containing an aluminum compound, wherein the pH when the hydrous gel is 100-fold diluted with purified water is from 6.5 to 8.5. A hydrous gel which can stably hold an ascorbic acid or a derivative thereof, has high gel strength, exhibits good adhesion to an adherend and causes no liquid syneresis can be provided.
US08580848B2	Benzofuran type derivatives, a composition comprising the same for treating or preventing cognitive dysfunction and the use thereof The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
US08580847B2	Antrocin containing pharmaceutical compositions for inhibiting cancer cells This subject invention is directed to a method for inhibition of cancer cells, comprising administrating an effective amount of a compound of formula I (Sesquiterpene lactones, antrocin) or pharmaceutically acceptable salts thereof, together with a pharmaceutically acceptable carrier, wherein the cancer cells are selected from colorectal cancer cells, liver cancer cells, lung cancer cells or breast cancer cells.
US08580846B2	Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders The invention is directed to a method of preventing or ameliorating a neuropsychiatric or neurodegenerative disease or disorder in a subject. The method includes administering a composition comprising equol in an amount sufficient to prevent or ameliorate the neuropsychiatric or neurodegenerative disease or disorder. The equol may be a racemic mixture of R-equol and S-equol. The equol may be enantiomerically enriched with R-equol or enantiomerically enriched with S-equol.
US08580845B2	Functionalized expanded porphyrins Disclosed are functionalized expanded porphyrins that can be used as spectrometric sensors for high-valent actinide cations. The disclosed functionalized expanded porphyrins have the advantage over unfunctionalized systems in that they can be immobilized via covalent attachment to a solid support comprising an inorganic or organic polymer or other common substrates. Substrates comprising the disclosed functionalized expanded porphyrins are also disclosed. Further, disclosed are methods of making the disclosed compounds (immobilized and free), methods of using them as sensors to detect high valent actinides, devices that comprise the disclosed compounds, and kits.
US08580842B2	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R3, R4, R5, R6, and R7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivatives can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.
US08580841B2	Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia): and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 receptor-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, microbial infections or diseases and viral infections or diseases.
US08580840B2	Tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators The present invention is directed to novel tetracyclic heteroatom containing derivatives, pharmaceutical compositions containing them, their use in the treatment of disorders mediated by one or more sex steroid hormone receptors and processes for their preparation.
US08580839B2	Photosensitizer formulations and their use A new treatment regime is presenter using a low concentration formulation at a low dosage of hydrophobic photosensitizers (PS) that shows improved pharmacokinetics and an effective method for photodynamic therapy (“PDT”). The new formulation has better pharmacological effect compared to standard photosensitizer formulation with standard dosage. It was found that PDT treatments using the disclosed low concentration formulations provide for more accurate, more efficient and more convenient dosing. It was found that the inventive formulation; (1) reduces the time for a therapeutically effective level of photosensitizer to accumulate in diseased tissue; and, (2) reduces the time for achieving a sufficient ratio of photosensitizer in diseased tissue vs. healthy tissue. As a result, the formulation of the invention reduces the time interval between PS application/administration and irradiation (the drug-light interval or “DLI”) and can provide for a “same day” PDT treatment option. The inventive formulation can be used for PDT treatment regimes where photosensitizers are administered in at least one preselected dose, including a low concentration therapy for PDT. In particular, when meta-(Tetrahydroxyphenyl)Chlorin (m-THPC) is the photosensitizer, then a concentration of 0.8 mg/ml to 0.04 mg/ml in a mixture of pure propylene glycol and ethanol in a 3:2 volume ratio accumulates in diseased tissue and differentiates between diseased tissue and normal tissue sufficiently quickly for ‘one day’ or overnight administration and activation treatment procedures to be possible.
US08580832B2	Substituted phenoxy aminothiazolones as estrogen related receptor-α modulators The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.
US08580825B2	Oxadiazole inhibitors of leukotriene production The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
US08580824B2	Pyridin-4-yl derivatives as immunomodulating agents The invention relates to pyridine derivatives of Formula (I) wherein A, R1, R2, R3, R4, R5, and R6 are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
US08580820B2	Tubulysin compounds with high cytotoxicity, pharmaceutical compositions thereof, and method of use thereof Tubulysine compounds of formula (A) having a high cytotoxicity wherein: B is selected from CH2, CH2—CH2 or CH2—CH2—CH2, D is an aromatic linker, X1 is alkyl or alkenyl, X2 is selected from the X2a, substituted or non substituted, selected from: aryl, heteroaryl, arylalkyl, cycloalkylalkyl, heterocycloalkylalkyl, or heteroarylalkyl, X2b: alkylene-O-alkyl, wherein alkylene is C2-C10, X2c: CH2—O-alkyl, X3 is selected from H, or together with X4 forms the group ═O, X4 is selected from H, halogen, OH, SH, alkyl, alkenyl, (OR5)n—OR6, OC(O)R7, NR6R7, or together with X4 forms the group ═O, R5 is an alkylene, n is zero or an integer from 1 to 10, R6 and R7, equal to or different from each other, have the following meanings: z1: H, alkyl, z2 substituted or non substituted: aryl, heteroaryl, cycloalkyl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl, heterocycloalkyl-alkyl, X5 is z2, or has the meaning of z3-alkyl, alkenyl, X6 is selected from NR8R9, OR8, NH—NR8R9, SR8, R10, wherein R8 and R9, equal to or different from each other, have the same meanings of R6, R10 has the same meanings as R6 but excluding H, X7 is z3 or H, X8 is selected from z3, H, halogen, OH, SH, OCH3.
US08580814B2	Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer Methods of treating, preventing or managing cancer, including certain leukemias are disclosed. The methods encompass the administration of enantiomerically pure (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed.
US08580813B2	Cyclic azaindole-3-carboxamides, their preparation and their use as pharmaceuticals The present invention relates to cyclic azaindole-3-carboxamides of the formula I, wherein A, R, R10, R20, R30, R40, Y1, Y2, Y3, Y4, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.
US08580812B2	Heteroaryl amide analogues as P2X7 antagonists Heteroaryl amide analogues are provided, of Formula (I), wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
US08580811B2	Androgen receptor modulator methods Provided herein are compounds that bind to androgen receptors and/or modulate activity of androgen receptors, and to methods for making and using such compounds. Also provided are compositions including such compounds and methods for making and using such compositions.
US08580803B2	Substituted pyrrolo-aminopyrimidine compounds The present invention relates to substituted pyrrolo-aminopyrimidine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted pyrrolo-aminopyrimidine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. The substituted pyrrolo-aminopyrimidine compounds have the following general formula:
US08580802B2	Pyrrolo[2,3-D]pyrimidines as inhibitors of Janus kinases The present invention relates to compounds of the following structural formula: which are useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
US08580800B2	1,4-diaryl-pyrimidopyridazine-2,5-diones and their use The present invention relates to novel 1,4-diarylpyrimido[4,5-d]pyridazine-2,5-dione derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
US08580799B2	Fungicide hydroximoyl-heterocycles derivatives The present invention relates to hydroximoyl-heterocycle derivatives of formula (I) wherein T represents a substituted or non-substituted heterocyclyl group, Q represents a carbo or heterocyclic group, A represent a carbo or heterocyclic group or a carbo or hetero-polycylic group, and L1 represents various linking groups, their process of preparation, intermediate compounds for their preparation, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
US08580796B2	Low hygroscopic aripiprazole drug substance and processes for the preparation thereof The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous Aripiprazole crystals is stored for an extended period.
US08580795B2	Heterocyclic compounds as phosphodiesterase inhibitors Compounds of the formula (I), their derivatives, analogs, tautomeric forms, regioisomers, stereoisomers, polymorphs, solvates, intermediates, pharmaceutically acceptable salts, pharmaceutical compositions, N-oxides, metabolites and prodrugs thereof. These compounds are phosphodiesterase type 4 (PDE4) inhibitors. They are useful in the treatment of a variety of allergic or inflammatory diseases including asthma, COPD, chronic bronchitis, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, vernal conjuctivitis, psoriasis, rheumatoid arthritis, ulcerative colitis, Crohn's disease, uveitis, NASH and lupus.
US08580794B2	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
US08580791B2	Antiviral 6-{2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole bis-dihydrogen-phosphate salts Novel acid addition salts of 6-{2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole of following formula are disclosed, particularly a crystalline form of a bis-dihydrogenphosphate salt: Such compounds have particular advantages with regard to treatment of picornaviruses. Related pharmaceutical compositions and methods of treating a picornavirus infection are also disclosed.
US08580780B2	6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT2C receptor agonists for the treatment of 5-HT2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where: R6 is —S—R14; and other substituents are as defined in the specification.
US08580778B2	Substituted dihydropyrazolones and their use The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and haematological diseases and kidney diseases, and for promoting wound healing.
US08580777B2	Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIa The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoagulability or fibrotic changes.
US08580776B2	Compositions and methods for treating neurodegenerating diseases This invention provides agents, compositions, pharmaceutical compositions and methods for treating or slowing the progression of a neurodegenerating disease, such as Alzheimer's disease and a demyelinating disease.
US08580774B2	Use of DHEA derivatives for enhancing physical performance A method is disclosed for administering a DHEA derivative or a physiologically acceptable salt, ester or ether thereof for one of decreasing body weight, reducing adipose tissue, increasing endurance, as an anti-aging compound and generating production of red blood cells.
US08580773B2	Small-molecule inhibitors of the androgen receptor The present invention provides tetrahydropyrvinium (THP), derivatives thereof, benzoxazole compounds, and derivatives thereof. The present invention provides a method of using tetrahydropyrvinium (THP), derivatives thereof, benzoxazole compounds, and derivatives thereof.
US08580766B2	Glycosaminoglycan composition and method for treatment and prevention of interstitial cystitis The invention provides compositions and methods useful for the treatment and/or prevention of interstitial cystitis and/or a related urinary tract condition in man or in animals. Specifically, provided are compositions specially formulated for direct instillation into the bladder and/or parenteral use in the treatment and/or prevention of interstitial cystitis. Compositions adapted for direct instillation into the bladder and/or for systemic administration are provided comprised of therapeutic amounts of: chondroitin sulfate in combination with hyaluronan (hyaluronic acid) are provided. Compositions adapted for direct instillation into the bladder and/or for systemic administration are also provided comprised of therapeutic amounts of: chondroitin sulfate, hyaluronan (hyaluronic acid) and N-acetyl D-glucosamine.
US08580762B2	Substituted purine and 7-deazapurine compounds The present invention relates to substituted purine and 7-deazapurine compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
US08580755B2	Methods and compositions for treating inflammatory conditions The present invention is directed to methods of treating an inflammatory condition in a patient. This method includes providing a therapeutic agent that is a vascular endothelial growth factor receptor-3 (VEGFR-3) agonist or a nucleic acid molecule encoding a VEGFR-3 agonist. The present invention is further directed to pharmaceutical compositions and therapeutic systems for treating an inflammatory condition.
US08580748B2	Peptides for the treatment of hearing Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-α secretion through interaction with toll-like receptor signaling pathways. Experiments are described illustrating the efficacy of the compounds in treating otitis media, noise-induced hearing loss, age-related hearing loss, and improvement of ordinary hearing.
US08580744B2	Therapeutic formulations containing venom or venom anti-serum either alone or in combination for the therapeutic prophylaxis and therapy of neoplasms A method of treating a mammal prophylactically to prevent neoplastic development comprises administering to the mammal a therapeutic vaccine comprising venom and at least one adjuvant. The method optionally further comprises administering to the mammal at least one other therapeutically effective agent, e.g., an anti-inflammatory agent.
US08580742B2	Topical glutathione formulations for menopausal skin Topical compositions to address menopausal skin conditions comprise an effective amount of S-acyl glutathione derivative and a carrier. Methods for addressing menopausal skin conditions comprise applying a composition containing S-acyl glutathione derivative in a dermatologically acceptable carrier to skin tissue. The acyl group is a saturated or unsaturated aliphatic C12-C24 group, preferably an unsaturated C16-C24 group, most preferably an unsaturated C18 group. In particularly preferred embodiments, the acyl group is a linoleoyl group.
US08580739B2	Methods of reducing myocardial injury following myocardial infarction The present invention discloses methods of reducing injury resulting from cardiovascular disease, such as myocardial infarction, and/or promoting myocardial repair. The methods include administering an ephrin and pharmaceutical compositions including ephrins to a subject. Kits useful for accomplishing the same are also provided.
US08580736B2	Rspondin polypeptides as promoting factors of angiogenesis and vasculogenesis The present invention relates to the use of Rspondins, particularly Rspondin2 (Rspo2) or Rspondin3 (Rspo3) or Rspondin nucleic acids, or regulators or effectors or modulators of Rspondin, e.g. Rspo2 and/or Rspo3 to promote or inhibit angiogenesis and/or vasculogenesis, respectively. The invention is based on the demonstration that Rspo3 and Rspo2 are angiogenesis promoters, and the identification of Rspo2 and 3 as positive regulators of vascular endothelial growth factor (VEGF). These results indicate a major role for Rspondins, particularly Rspo3 and/or Rspo2 in the signaling system during angiogenesis. The invention also relates to the use of regulators or effectors or modulators of Rspondin3, including agonists and antagonists, in the treatment of conditions where treatment involves inhibiting or promoting angiogenesis and/or vasculogenesis.
US08580725B2	Aerosol product comprising a foaming concentrate composition comprising particulate materials An aerosol product comprises a foaming concentrate composition that comprises a surfactant and particulate material having a particle size of at least about 100 μm. The foaming concentrate composition and propellant are contained in a package comprising a container and a powder valve comprising an orifice having an orifice diameter of at least about 660 μm. Preferably, a ratio of the maximum particle size of the particulate material to the orifice diameter of the orifice is less than about 0.75.
US08580723B2	Process compositions and production of acyl alkylisethionate compositions Methods and compositions are provided for forming ester based compositions. The ester based compositions may be used in consumer products. In one aspect, a method is provided for producing acyl alkylisethionate esters by the esterification of a sulfonate composition having two or more sulfonate isomers with fatty acid(s). In another aspect, a method is provided for forming an ester based composition including a blend of acyl alkylisethionate and acylisethionate esters.
US08580721B2	Composition comprising substituted cellulosic polymer and amylase A solid particulate laundry detergent composition including: (a) substituted cellulosic polymer including carboxymethyl substituent groups, and having a degree of substitution (DS) of at least 0.55, and having a degree of blockiness (DB) of at least 0.35, and having a DS+DB is in the range of from 1.05 to 2.00; (b) amylase with greater than 90% identity to the AA560 alpha amylase endogenous to Bacillus sp. DSM 12649 and including: (i) mutations at one or more of positions 9, 149, 182, 186, 202, 257, 295, 299, 323, 339 and 345; and (ii) mutations at four or more of positions 118, 183, 184, 195, 320 and 458; and (c) laundry detergent ingredients.
US08580717B2	Process for making an overbased, sulfurized salt of an alkylated hydroxyaromatic compound An overbased, sulfurized salt of at least one alkylated hydroxyaromatic compound, wherein the alkyl substituent of the hydroxyaromatic compound is a residue of at least one isomerized olefin having from about 15 to about 99 wt. % branching is disclosed. The overbased, sulfurized salt of at least one alkylated hydroxyaromatic compound is produced by the process comprising: (a) alkylating at least one hydroxyaromatic compound with at least one isomerized olefin having from about 15 to about 99 wt. % branching obtained by isomerizing at least one normal alpha olefin having from about 10 to about 40 carbon atoms, to provide at least one alkylated hydroxyaromatic compound; (b) neutralizing and sulfurizing the alkylated hydroxyaromatic compound in any order to provide at least one neutralized, sulfurized alkylated hydroxyaromatic compound; and (c) overbasing the at least one neutralized, sulfurized alkylated hydroxyaromatic compound.
US08580714B2	Methods of affinity maturing antibodies The invention relates to methods of affinity maturing antibodies.
US08580712B2	Bis(dialkylamide) compounds and diverse applications thereof Novel bis(dialkylamide) compounds having the formula: R2R3NOC—R1a—CONR4R5 are particularly useful solvents, for example in plant-protection formulations.
US08580710B2	Pesticidal active mixtures comprising aminothiazoline compounds The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one aminothiazoline compound I of formula I: wherein variables R1, R2, R3, R4, R5, and R6 are as defined in the description of the application and 2) at least one active compound II selected from group A as defined in the description, use of these mixtures for combating insects, acarids, or nematodes, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using these mixtures.
US08580708B2	Plant cryoprotectant compositions and methods of use The present disclosure relates to cryoprotection of plants. The compositions and methods disclosed herein provide a means for protecting plants from frost or freeze damage or death due to sudden exposure to low temperature conditions. The present disclosure further relates to methods for providing cryoprotection to plants.
US08580703B2	Additive component for the improvement of the performance of olefin polymerisation catalysts The present invention relates to a catalyst composition for polymerising olefin monomers to polyolefins comprising a catalyst component and a first additive component. The first additive component is a fossil and may for example be obtained from coal.
US08580701B2	Method of controlling Ce:Zr ratio in oxide nanoparticles A method of making a nanoparticle catalyst composition including: a single heating of an aqueous salt solution comprising a Ce, a Zr, a rare earth dopant, and a transition metal oxide precursor to provide nanoparticles, the nanoparticles have a compositional gradient comprised of a CeZrREO2, where RE is a rare earth, and the outer portion of the nanoparticles has a Ce:Zr ratio different from the inner portion of the nanoparticles. Also disclosed is a nanoparticle-catalyst composition and articles containing the composition, as defined herein.
US08580696B2	Systems and methods for detecting watermark formations on semiconductor wafers Systems and methods for detecting watermark formations on semiconductor wafers are described. In one embodiment, a method comprises providing a semiconductor wafer having at least one watermark sensitive region fabricated thereon, subjecting the wafer to a wet processing step, enhancing a susceptibility to detection of at least one watermark formation created on the at least one watermark sensitive region, and detecting the at least one watermark formation. In another embodiment, a method comprises growing a first oxide layer on a surface of a semiconductor wafer, patterning a watermark sensitive structure on the first oxide layer, depositing a silicon layer over the first oxide layer, doping a region of the silicon layer over the watermark sensitive structure with an impurity to create a watermark sensitive region that is prone to retaining watermark formations as result of a wet processing step, and growing a second oxide layer over the silicon layer.
US08580694B2	Method of patterning hard mask layer for defining deep trench A method of patterning a hard mask layer for defining a deep trench is described. A substrate formed with an isolation structure therein is provided. A hard mask layer is formed over the substrate provided. A patterned photoresist layer is formed over the hard mask layer, having therein a deep-trench opening pattern over the isolation structure. An etching gas not containing hydrogen is used to etch the hard mask layer with the patterned photoresist layer as a mask and thereby transfer the deep-trench opening pattern to the hard mask layer.
US08580692B2	Film stack including metal hardmask layer for sidewall image transfer fin field effect transistor formation A method for formation of a fin field effect transistor (FinFET) device includes forming a mandrel mask and a large feature (FX) mask on a metal hardmask layer of a film stack, the film stack including a silicon on insulator (SOI) layer located underneath the metal hardmask layer; etching the mandrel mask and the FX mask simultaneously into the metal hardmask layer; and etching the mandrel mask and the FX mask into the SOI layer using the etched metal hardmask layer as a mask.
US08580689B2	Plasma processing method The present invention provides a dry etching method capable of readily providing rounded top edge portions, called top rounds, at trenches and vias formed by removal of a dummy material. The method of the present invention is a dry etching method for forming trenches or vias by removing a dummy material with its periphery surrounded by an interlayer oxide film, which method includes the steps of etching the dummy material to a predetermined depth, performing isotropic etching after the dummy material etching, and removing remaining part of the dummy material after the isotropic etching.
US08580688B2	Copper interconnection structure and method for forming copper interconnections A copper interconnection structure includes an insulating layer, an interconnection body including copper in an opening provided on the insulating layer, and a diffusion barrier layer formed between the insulating layer and the interconnection body. The diffusion barrier layer includes an oxide layer including manganese having a compositional ratio of oxygen to manganese (y/x) less than 2.
US08580678B2	Method for fabricating semiconductor device with buried gates A method for fabricating a semiconductor device includes forming first plugs over a substrate, forming contact holes that expose the first plugs, ion-implanting an anti-diffusion material into the first plugs, and forming second plugs filling the contact holes.
US08580677B2	Method of manufacturing substrate including thin film transistor A substrate including a thin film transistor, the substrate including an active layer disposed on the substrate, the active layer including a channel area and source and drain areas, a gate electrode disposed on the active layer, the channel area corresponding to the gate electrode, a gate insulating layer interposed between the active layer and the gate electrode, an interlayer insulating layer disposed to cover the active layer and the gate electrode, the interlayer insulating layer having first and second contact holes partially exposing the active layer, source and drain electrodes disposed on the interlayer insulating layer, the source and drain areas corresponding to the source and drain electrodes, and ohmic contact layers, the ohmic contact layers being interposed between the interlayer insulating layer and the source and drain electrodes, and contacting the source and drain areas through the first and second contact holes.
US08580674B2	Fabrication of atomic scale devices This invention concerns the fabrication of nano to atomic scale devices, that is electronic devices fabricated down to atomic accuracy. The fabrication process uses either an SEM or a STM tip to pattern regions on a semiconductor substrate. Then, forming electrically active parts of the device at those regions. Encapsulating the formed device. Using a SEM or optical microscope to align locations for electrically conducting elements on the surface of the encapsulating semiconductor with respective active parts of the device encapsulated below the surface. Forming electrically conducting elements on the surface at the aligned locations. And, electrically connecting electrically conducting elements on the surface with aligned parts of the device encapsulated below the surface to allow electrical connectivity and tunability of the device. In further aspects the invention concerns the devices themselves.
US08580669B2	Method for fabricating semiconductor device A method for forming a semiconductor device is disclosed. A method for forming a semiconductor device includes forming a first bit line contact over a semiconductor substrate, forming a second bit line contact that is coupled to the first bit line contact and has a larger width than the first bit line contact, and forming a bit line over the second bit line contact. When using the semiconductor device having a buried gate, although the bit line is formed to have a small width and the bit line pattern is misaligned, the method prevents incorrect coupling between a bit line and a bit line contact, so that it basically deteriorates unique characteristics of the semiconductor device.
US08580667B2	Self aligned trench MOSFET with integrated diode Transistor devices can be fabricated with an integrated diode using a self-alignment. The device includes a doped semiconductor substrate having one or more electrically insulated gate electrodes formed in trenches in the substrate. One or more body regions are formed in a top portion of the substrate proximate each gate trench. One or more source regions are formed in a self-aligned fashion in a top portion of the body regions proximate each gate trench. One or more thick insulator portions are formed over the gate electrodes on a top surface of the substrate with spaces between adjacent thick insulator portions. A metal is formed on top of the substrate over the thick insulator portions. The metal forms a self-aligned contact to the substrate through the spaces between the thick insulator portions. An integrated diode is formed under the self-aligned contact.
US08580666B2	Methods of forming conductive contacts Methods for forming memory devices and integrated circuitry, for example, DRAM (dynamic random access memory) circuitry, structures and devices resulting from such methods, and systems that incorporate the devices are provided.
US08580665B2	MOSFET integrated circuit having doped conductive interconnects and methods for its manufacture An integrated circuit device having doped conductive contacts, and methods for its fabrication, are provided. One such method involves depositing a dielectric layer on the surface of a silicon semiconductor substrate, and photolithographically patterning a plurality of contact trenches on the dielectric layer. A tantalum barrier is deposited in the trenches, followed by a copper seed layer. The trenches are then plated with copper, including an overburden. A layer of doping material is deposited atop the overburden, and diffused into the copper by a heat treatment process. The overburden is then removed through chemical mechanical planarization, resulting in usable conductive interconnects in the trenches.
US08580663B2	Formation of shallow junctions by diffusion from a dielectronic doped by cluster or molecular ion beams A process for forming diffused region less than 20 nanometers deep with an average doping dose above 1014 cm−2 in an IC substrate, particularly LDD region in an MOS transistor, is disclosed. Dopants are implanted into a source dielectric layer using gas cluster ion beam (GCIB) implantation, molecular ion implantation or atomic ion implantation resulting in negligible damage in the IC substrate. A spike anneal or a laser anneal diffuses the implanted dopants into the IC substrate. The inventive process may also be applied to forming source and drain (S/D) regions. One source dielectric layer may be used for forming both NLDD and PLDD regions.
US08580661B1	Method for the hydrogenation of poly-si A method for hydrogenating poly-si. Poly-si is placed into the interior of a chamber. A filament is placed into the interior of a chamber. The base pressure of the interior of the chamber is evacuated, preferably to 10−6 Torr or less. The poly-si is heated for a predetermined poly-si heating time. The filament is heated by providing an electrical power to the filament. Hydrogen is supplied into the pressurized interior of the chamber comprising the heated poly-si and the heated filament. Atomic hydrogen is produced by the filament at a rate whereby the atomic hydrogen surface density at the poly-si is less than the poly-si surface density. Preferably, the poly-si is covered from the atomic hydrogen produced by the heated filament for a first predetermined covering time. Preferably, the poly-si is then uncovered from the atomic hydrogen produced by the heated filament for a first hydrogenation time.
US08580658B1	Methods for fabricating graphene device topography and devices formed therefrom Methods for forming graphite-based structures, in which a substrate is patterned to form a plurality of elements on the substrate, are provided. A trench separates a first element from an adjacent element in the plurality. The surface of the first element and the surface of the trench (i) are respectively characterized by different first and second elevations and (ii) are separated by a side wall of the first element. Orthogonal projections of the surface of the first element and the surface of the trench onto a common plane are contiguous or overlapping. In the method, a first graphene layer on the entire first surface and a second graphene layer on the entire second surface are concurrently generated. The second graphene layer has a thickness that is less than a difference between the first and second elevations. Thus, a graphite-based structure having isolated first and second graphene layers is formed.
US08580654B2	Method for molecular bonding of silicon and glass substrates The present invention concerns a method for bonding a first substrate having a first surface to a second substrate having a second surface. This method includes the steps of holding the first substrate by at least two support points, positioning the first substrate and the second substrate so that the first surface and the second surface face each other, deforming the first substrate by applying between at least one pressure point and the two support points a strain toward the second substrate, bringing the deformed first surface and the second surface into contact, and progressively releasing the strain to facilitate bonding of the substrates while minimizing or avoiding the trapping of air bubbles between the substrates.
US08580652B2	Semiconductor device and manufacturing method thereof According to one embodiment, a manufacturing method of a semiconductor device is disclosed. The semiconductor device includes a semiconductor substrate having first and second main surfaces, and a through hole passing through between the first and second main surfaces, a pad on the first main surface, a through electrode in the through hole, and a connection structure including a connection portion to directly connect the pad and the through electrode, and another connection portion to indirectly connect the pad and the through electrode. The method includes forming an isolation region in the first main surface, the isolation region being in a region where the through electrode is to be formed and being in a region other than the region where the through hole is to be formed, forming the pad, and forming the through hole by processing the substrate to expose a part of the pad.
US08580651B2	Methods for manufacturing a trench type semiconductor device having a thermally sensitive refill material Methods for manufacturing trench type semiconductor devices involve refilling the trenches after high temperature processing steps are performed. The methods allow thermally unstable materials to be used as refill materials for the trenches of the device. Trench type semiconductor devices containing thermally unstable refill materials are also provided. In particular, methods of manufacturing and devices of a trench type semiconductor devices containing organic refill materials are provided.
US08580648B2	Capacitor having an electrode structure, method of manufacturing a capacitor having an electrode structure and semiconductor device having an electrode structure A capacitor includes an object or a substrate including an insulation layer having an opening, an electrode structure having conductive patterns, a dielectric layer and an upper electrode. The electrode structure may have a first conductive pattern including metal and a second conductive pattern including metal oxide generated from the first conductive pattern. The first conductive pattern may fill the opening and may protrude over the insulation layer. The second conductive pattern may extend from the first conductive pattern. The electrode structure may additionally include a third conductive pattern disposed on the second conductive pattern. The capacitor including the electrode structure may ensure improved structural stability and electrical characteristics.
US08580643B2	Threshold voltage adjustment in a Fin transistor by corner implantation When forming sophisticated multiple gate transistors and planar transistors in a common manufacturing sequence, the threshold voltage characteristics of the multiple gate transistors may be intentionally “degraded” by selectively incorporating a dopant species into corner areas of the semiconductor fins, thereby obtaining a superior adaptation of the threshold voltage characteristics of multiple gate transistors and planar transistors. In advantageous embodiments, the incorporation of the dopant species may be accomplished by using the hard mask, which is also used for patterning the self-aligned semiconductor fins.
US08580640B2	Manufacturing process of a power electronic device integrated in a semiconductor substrate with wide band gap and electronic device thus obtained An embodiment of a process for manufacturing an electronic device on a semiconductor body of a material with wide forbidden bandgap having a first conductivity type. The process comprises the steps of: forming, on the semiconductor body, a first mask having a first window and a second window above a first surface portion and a second surface portion of the semiconductor body; forming, within the first and second surface portions of the semiconductor body underneath the first and second windows, at least one first conductive region and one second conductive region having a second conductivity type, the first conductive region and the second conductive region facing one another; forming a second mask on the semiconductor body, the second mask having a plurality of windows above surface portions of the first conductive region and the second conductive region; forming, within the first conductive region and the second conductive region and underneath the plurality of windows, a plurality of third conductive regions having the first conductivity type; removing completely the first and second masks; performing an activation thermal process of the first, second, and third conductive regions at a high temperature; and forming body and source regions.
US08580634B1	Methods of forming 3-D semiconductor devices with a nanowire gate structure wherein the nanowire gate structure is formed prior to source/drain formation In one example, the method disclosed herein includes forming a fin comprised of a semiconducting material, wherein the fin has a first, as-formed cross-sectional configuration, forming a patterned hard mask above the fin, wherein the patterned hard mask has an opening that exposes a portion of the fin, performing a fin reflow process through the opening in the patterned hard mask on the exposed portion of the fin to define a nanowire structure having a cross-sectional configuration that is different from the first cross-sectional configuration, and forming a gate structure that extends at least partially around the nanowire structure.
US08580632B2	Semiconductor device and method of manufacturing same To provide a semiconductor device and a method of manufacturing the same capable of suppressing, when a plurality of MIS transistors having different absolute values of threshold voltage is used, the reduction of the drive current of a MIS transistor having a greater absolute value of threshold voltage.The threshold voltage of a second nMIS transistor is greater than the threshold voltage of a first nMIS transistor and the sum of the concentration of lanthanum atom and the concentration of magnesium atom in a second nMIS high-k film included in the second nMIS transistor is lower than the sum of the concentration of lanthanum atom and the concentration of magnesium atom in a first nMIS high-k film included in the first nMIS transistor.
US08580631B2	High sheet resistor in CMOS flow An integrated circuit containing CMOS gates and a counterdoped polysilicon gate material resistor which has a body region that is implanted concurrently with the NSD layers of the NMOS transistors of the CMOS gates and concurrently with the PSD layers of the PMOS transistors of the CMOS gates, and has a resistor silicide block layer over the body region which is formed of separate material from the sidewall spacers on the CMOS gates. A process of forming an integrated circuit containing CMOS gates and a counterdoped polysilicon gate material resistor which implants the body region of the resistor concurrently with the NSD layers of the NMOS transistors of the CMOS gates and concurrently with the PSD layers of the PMOS transistors of the CMOS gates, and forms a resistor silicide block layer over the body region of separate material from the sidewall spacers on the CMOS gates.
US08580627B2	Compound semiconductor device and method for fabricating the same A compound semiconductor device is provided, including a gallium arsenide (GaAs) substrate having a first protrusion portion and a second protrusion portion, wherein the first protrusion portion is formed over a first portion of the GaAs substrate and the second protrusion is formed over a second portion of the GaAs substrate. A first element is disposed over the first protrusion portion, and a second element is disposed over the second protrusion portion.
US08580622B2	Method of making integrated circuit embedded with non-volatile programmable memory having variable coupling A programmable non-volatile device is made with a floating gate that functions as a FET gate that overlaps a portion of a source/drain region and allows for variable coupling through geometry and/or biasing conditions. This allows a programming voltage for the device to be imparted to the floating gate through variable capacitive coupling, thus changing the state of the device. Multi-state embodiments are also possible. The invention can be used in environments such as data encryption, reference trimming, manufacturing ID, security ID, and many other applications.
US08580619B2	Method for producing semiconductor device A method for producing a semiconductor device, including a semiconductor chip, for improving production efficiency and the flexibility of production design is provided. The method comprises: preparing a semiconductor chip having a first main surface on which an electroconductive member is formed; preparing a supporting structure in which, over a support configured to transmit radiation, a radiation curable pressure-sensitive adhesive layer and a first thermosetting resin layer are laminated in this order; arranging the semiconductor chips on the first thermosetting resin layer to face the first thermosetting resin layer to a second main surface of the semiconductor chips opposite to the first main surface; laminating a second thermosetting resin layer over the first thermosetting resin layer to cover the semiconductor chips; and curing the radiation curable pressure-sensitive adhesive layer by irradiating from the support side to peel the radiation curable pressure-sensitive adhesive layer from the first thermosetting resin layer.
US08580617B2	Thermosetting die-bonding film The thermosetting die-bonding film of the present invention is used in manufacturing a semiconductor device, has at least an epoxy resin, a phenol resin, and an acrylic copolymer, and the ratio X/Y is 0.7 to 5 when X represents a total weight of the epoxy resin and the phenol resin and Y represents a weight of the acrylic copolymer.
US08580613B2	Semiconductor chip arrangement with sensor chip and manufacturing method On a carrier (1) an adhesion layer (4), an ASIC chip (2) and a sensor chip (3) are arranged one above another. An interchip connection (5) is provided for electrically connecting the chips among one another, and an ASIC connection (6) is provided for externally electrically connecting the circuit integrated in the ASIC chip.
US08580611B2	Method for manufacturing wiring substrate A method for manufacturing a wiring substrate includes forming a first pad and a second pad on one side of a substrate, plating a surface of the second pad to form a bonding pad used for a wire-bonded connection, covering a surface of the first pad with an adhesive layer, adhering solder powder to the adhesive layer, applying flux containing halogen to the substrate, and melting the solder powder and covering the first pad with a solder to form a connection pad used for a flip-chip-connection. The flux has a halogen concentration of less than or equal to 0.15 wt %.
US08580599B2	Bypass diode for a solar cell Methods of fabricating bypass diodes for solar cells are described. In one embodiment, a method includes forming a first conductive region of a first conductivity type above a substrate of a solar cell. A second conductive region of a second conductivity type is formed on the first conductive region. In another embodiment, a method includes forming a first conductive region of a first conductivity type above a substrate of a solar cell. A second conductive region of a second conductivity type is formed within, and surrounded by, an uppermost portion of the first conductive region but is not formed in a lowermost portion of the first conductive region.
US08580598B2	Image sensor and method of manufacturing the same Disclosed are an image sensor and a method of manufacturing the same. A metal wiring consisting of a lower metal wiring, an upper metal wiring, and a plug connecting the lower and upper metal wirings, in which the lower and upper metal wiring are made of a transparent conductive film pattern, is formed on a substrate with devices formed thereon, the devices including a photodiode and gate electrodes. Then, a passivation film, a color filter, and a microlens are sequentially formed on the metal wiring. All or a portion of the metal wiring is formed in a transparent conductive film pattern. As such, the metal wiring is formed on the photodiode.
US08580596B2	Front end micro cavity The present invention relates to a method of forming a micro cavity having a micro electrical mechanical system (MEMS) in a process, such as a CMOS process. MEMS resonators are being intensively studied in many research groups and some first products have recently been released. This type of device offers a high Q-factor, small size, high level of integration and potentially low cost. These devices are expected to replace bulky quartz crystals in high-precision oscillators and may also be used as RF filters. The oscillators can be used in time-keeping and frequency reference applications such as RF modules in mobile phones, devices containing blue-tooth modules and other digital and telecommunication devices.
US08580593B2	Epitaxial formation structures and associated methods of manufacturing solid state lighting devices Epitaxial formation structures and associated methods of manufacturing solid state lighting (“SSL”) devices with target thermal expansion characteristics are disclosed herein. In one embodiment, an SSL device includes a composite structure having a composite CTE temperature dependency, a formation structure on the composite structure, and an SSL structure on the formation structure. The SSL structure has an SSL temperature dependency, and a difference between the composite CTE and SSL temperature dependencies is below 3 ppm/° C. over the temperature range.
US08580588B2	Organic light emitting display device and fabricating method thereof An organic light emitting display includes a substrate, a semiconductor layer arranged on the substrate, an organic light emitting diode arranged on the semiconductor layer, an encapsulant arranged on an top surface periphery of the substrate, which is an outer periphery of the semiconductor layer and the organic light emitting diode, an encapsulation substrate bonded to the encapsulant, and a bonding agent arranged on an under surface of the substrate which is opposite to the encapsulant.
US08580586B2	Memory arrays using nanotube articles with reprogrammable resistance A memory array includes a plurality of memory cells, each of which receives a bit line, a first word line, and a second word line. Each memory cell includes a cell selection circuit, which allows the memory cell to be selected. Each memory cell also includes a two-terminal switching device, which includes first and second conductive terminals in electrical communication with a nanotube article. The memory array also includes a memory operation circuit, which is operably coupled to the bit line, the first word line, and the second word line of each cell. The circuit can select the cell by activating an appropriate line, and can apply appropriate electrical stimuli to an appropriate line to reprogrammably change the relative resistance of the nanotube article between the first and second terminals. The relative resistance corresponds to an informational state of the memory cell.
US08580574B2	Method and apparatus for stripping a contact-limiting element from a pipette probe An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
US08580573B2	Highly fluorescent markers for fluids or articles The present invention provides highly fluorescent markers, made from a reactive polymer and an isocyanate, that fluoresce in the ultraviolet or near infrared region without being visible to the human eye at low concentrations in the fluid or article being marked. The molecular weight and fluorescence emission wavelength of these highly fluorescent marker compounds can be adjusted to provide a multitude of markers with unique fluorescence signatures.
US08580572B2	Lateral flow assay test strip and method of making the same The invention relates to a lateral flow assay test strip and a method for making the same. The strip comprises, in the flow direction, a selectively activated membrane for a test reaction and an absorption pad, which are both made of paper and may comprise an integral paper strip. The absorption pad has the paper strip embossed and/or folded to increase the strip's absorption capacity. The folded pad may have an accordion-like configuration, the strip running to-and-from, or it may have the strip rolled and then flattened to a stack of layers.
US08580571B2	Method for producing a biosensor Thus, the present invention provides a method for producing a biosensor comprising a substrate coated with a hydrophilic polymer, which comprises allowing a compound generating a reactive group as a result of external stimulus to bind to the surface of a substrate, and then giving external stimulus in a state where a hydrophilic polymer capable of forming a covalent bond with said reactive group is allowed to come into contact with the substrate, so that said hydrophilic polymer is allowed to bind to the substrate surface via a covalent bond with said reactive group.
US08580569B2	Feedback control in microfluidic systems Systems and methods for controlling fluids in microfluidic systems are generally described. In some embodiments, control of fluids involves the use of feedback from one or more processes or events taking place in the microfluidic system. For instance, a detector may detect one or more fluids at a measurement zone of a microfluidic system and one or more signals, or a pattern of signals, may be generated corresponding to the fluid(s). In some cases, the signal or pattern of signals may correspond to an intensity, a duration, a position in time relative to a second position in time or relative to another process, and/or an average time period between events. Using this data, a control system may determine whether to modulate subsequent fluid flow in the microfluidic system. In some embodiments, these and other methods can be used to conduct quality control to determine abnormalities in operation of the microfluidic system.
US08580566B2	Apparatus for and method of preparing plant tissue for plant production An apparatus for preparing plant tissue (e.g., somatic embryos, embryogenic tissue, organogenic tissue, vegetative tissue, seeds, etc.) for plant production includes a first station having a first rack system configured to support at least one culture vessel, a second station having an automated member configured to manipulate the at least one culture vessel and a third station having a second rack system configured to support the at least one culture vessel after being manipulated by the automated member. The second station can be selectively adjusted to perform more than one operation required in the plant development. According to exemplary embodiments, the apparatus may include more than one second station (e.g., operational stations, etc.).
US08580561B2	Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for dermatological conditions, gastroesophageal reflux, vesico-ureteral reflux, urinary incontinence, fecal incontinence, heart failure, and myocardial infarction.
US08580558B2	Methods for isolation, use and analysis of ferritin This invention provides methods of isolating ferritin from plant and animal material. The isolated ferritin can be administered to humans or animals in need of iron, and can be used to treat or supplement iron deficiency. The isolated ferritin can be used in industrial applications, such as increasing the iron content in heat-processed food or beverages. The methods of the invention also include quantitation of iron derived from plant or animal ferritin.
US08580556B2	Sulfonylurea-responsive repressor proteins Compositions and methods relating to the use of sulfonylurea-responsive repressors are provided. Compositions include polypeptides that specifically bind to an operator, wherein the specific binding is regulated by a sulfonylurea compound. Compositions also include polynucleotides encoding the polypeptides as well as constructs, vectors, prokaryotic and eukaryotic cells, and eukaryotic organisms including plants and seeds comprising the polynucleotide, and/or produced by the methods. Also provided are methods to provide a sulfonylurea-responsive repressor to a cell or organism, and to regulate expression of a polynucleotide of interest in a cell or organism, including a plant or plant cell.
US08580552B2	Method for treating cellulosic material and CBHII/CEL6A enzymes useful therein The present invention relates to the production of sugar hydrolysates from cellulosic material. The method may be used, for example for producing fermentable sugars for the production of bioethanol from lignocellulosic material. Cellulolytic enzymes and their production by recombinant technology are described, as well as uses of the enzymes and enzyme preparations.
US08580550B2	Lipase powder, method for manufacture thereof, and use thereof There is provided a lipase powder which is a granulated material comprising a lipase and at least one member selected from the group consisting of fatty acids having 8 to 12 carbon atoms, alcohol esters thereof, and a mixture thereof. This lipase powder has an increased lipase activity.
US08580546B2	Micro-organ device A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel.
US08580542B2	Methods and compositions for producing alkenes of various chain length The NonA alkene synthase in Synechococcus sp. displays selective synthesis of 1-nonadecene. Heterologous recombination of a domain, i.e. the acyl binding domain, with other acyl binding proteins, affects acyl substrate chain-length binding selectivity and therefore the chain-length of the synthesized 1-alkenes. Compositions and methods are provided to selectively synthesize 1-alkenes of various chain lengths.
US08580535B2	Mass spectrometric measurement of microbial resistances Microorganisms, particularly bacteria, are identified and characterized on the basis of a mass spectrometric measurement of their protein profiles with ionization by matrix-assisted laser desorption. In order to measure the microbial resistance to antibiotics, the protein profiles of microorganisms are measured after cultivation for a short time duration in nutrient media containing the antibiotics.
US08580528B2	Method for prognosticating the clinical response of a patient to B-lymphocyte inhibiting or depleting therapy The invention relates to methods for predicting a clinical response to B-lymphocyte inhibiting or depleting therapies (BCIDT) using expression levels of genes of the Type I INF pathway. In another aspect, the invention relates to a method for evaluating a pharmacological effect of a treatment with B-lymphocyte inhibiting or depleting therapy. More in particular, the invention relates to a method for prognosticating the clinical response of a patient to treatment with a soluble BCID or TCID agent, said method comprising the steps of obtaining at least two samples from said patient wherein a first sample has not been exposed to a soluble BCID or TCID agent and wherein at least a second sample has been exposed to a soluble BCID or TCID agent, determining the level of an IFN-I type response in said at least two samples, comparing the level of the IFN-I type response in said first sample with the level of the IFN-I type response in said at least second sample and prognosticating said clinical response from said comparison.
US08580523B2	Specific marker Lmx1a on dopaminergic neurons The present invention identified Lmx1a genes, which are expressed in dopaminergic neurons at all differentiation stages, from proliferating dopaminergic neuron progenitor cells before cell cycle exit to cells after cell cycle exit. Lmx1a expression in cells can be used as an indicator when selecting cells suitable for transplantation therapy for neurodegenerative diseases such as Parkinson's disease, and is useful as a marker for screening agents involved in the induction of dopaminergic neuron differentiation.
US08580517B2	Biosensor and use thereof to identify therapeutic drug molecules and molecules binding orphan receptors G protein biosensors comprising mammalian G protein subunits fused to fluorescent proteins emitting a FRET signal expressed in living intact functional cells. The intensity of the FRET signal is strongly responsive to the activation state of the biosensors. The biosensors respond reproducibly to agonist and antagonist drug molecules specific for G protein coupled receptors. The biosensors have utility in identifying and classifying candidate therapeutic drugs as to their therapeutic value.
US08580516B2	Methods and compositions for direct detection of DNA damage The present invention is a method for detecting the extent of DNA damage in a subject suspected of having DNA damage wherein the damage results in the formation of aldehyde moieties in DNA comprising, obtaining a DNA sample from the subject, combining the DNA sample with a fluorescent, chromogenic, pro-fluorescent or pro-chromogenic hydrazine compound to from a fluorescent DNA, detecting the presence of the fluorescent DNA by monitoring the fluorescent emission and quantitating the fluorescent emission thereby determining the extent of DNA damage in the subject.
US08580514B2	Microchip for identifying Phellinus species and the method thereof The developed oligonucleotide microchip for simultaneous, rapid identification of multiple crucial forest Phellinus pathogens was based on the DIG or biotin-labeled specific probes derived form ribosomal DNA genes (ITS1-5.8S-ITS2), by using reverse-dot hybridization. The chip can precisely and accurately identify and diagnose seventeen Phellinus species, including notorious hardwood and conifer tree killer, P. noxius and P. weirii, with a sensitivity of 1 pg DNA/μl on Nylon membrane, and 100 fg DNA/μl on plastic chip, respectively. Verification and identification of forest Phellinus pathogens infested authentic samples or voucher specimens can be accomplished within 7 hr.
US08580513B2	Methods for determining response to neoadjuvant therapy and survival using MicroRNA-10b The present invention provides methods for determining response to neoadjuvant therapy and metastasis-free survival in pancreatic ductal adenocarcinoma based upon the level of microRNA expression and optionally the presence of a protein cancer cell marker in biological samples such as formalin-fixed paraffin-embedded specimens using in situ hybridization and optionally an immunohistochemical assay.
US08580503B2	Methods and compositions for diagnosing complications of pregnancy The present invention provides methods and compositions for identifying subjects at risk of developing a complication of pregnancy, such as preeclampsia or preterm labor. The compositions are microRNAs and associated nucleic acids.
US08580502B2	Methods of screening a subject for FHL1 mutations associated with novel X-linked muscular myopathies Four and a Half LIM domains protein 1 (FHL-1) mutations at positions 128 or 224 that are associated with X-linked muscular myopathy, methods of screening subjects to identify those susceptible to muscular myopathy including muscular dystrophy and cardiomyopathy and kits.
US08580500B2	Methods for diagnosing lung cancer using microRNAs The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
US08580494B2	Methods and compositions for amplification and detection of MicroRNAs A method and system for amplifying non-coding RNA, microRNA, and small polynucleotide sequences through the generation of a pool of signature sequences to the target sequences. The target sequences can be amplified through DNA synthesis, RNA synthesis, or the combination of DNA and RNA synthesis. The amplification of signature sequences provides an efficient and reproducible mechanism to determine the presence or absence of the miRNAs, to analyze the quantities of the target miRNAs, and for miRNA profiling. The method may also be used for screening for unknown non-coding RNAs, including novel miRNAs.
US08580491B2	Cancer diagnosis marker using the aberrant glycosylation of a protein The present invention relates to a method for diagnosing cancer using information on the aberrant glycosylation of a glycoprotein. More precisely, the present invention relates to a cancer diagnosis peptide marker, which is screened by: a step of separating, using a lectin, a glycoprotein which is aberrantly glycosylated in accordance with the occurrence of cancer; and a step of selecting a hydrolyzed peptide marker derived from the aberrantly glycosylated glycoprotein by observing the quantitative changes in the separated glycoprotein. The present invention also relates to a method for diagnosing cancer using the peptide marker as an agent.
US08580482B2	Copolymer and top coating composition A resin composition for forming a top coat which can be formed on a photoresist film without causing intermixing with the photoresist film, can maintain a stable film coating which is not eluted into a medium during immersion lithography, does not impair pattern profiles during dry exposure (which is not immersion lithography), and can be easily dissolved in an alkaline developer. The resin is a copolymer which includes at least one recurring unit (I) selected from the group consisting of a recurring unit having a group shown by the following formula (1), a recurring unit having a group shown by the following formula (2), and a recurring unit having a carboxyl group, and a recurring unit (II) having a sulfo group, the copolymer having a weight average molecular weight determined by gel permeation chromatography of 2,000 to 100,000.
US08580481B2	Resist polymer and resist composition The resist polymer of the present invention comprises a specific constitutional unit having a cyano group, a constitutional unit having an acid-dissociable group, and a specific constitutional unit having a lactone skeleton. When the above polymer is used as a resist resin in DUV excimer laser lithography or electron beam lithography, it exhibits high sensitivity and high resolution, and provides a good resist pattern shape, having a small degree of occurrence of line edge roughness or generation of microgels.
US08580479B2	Lithography using photoresist with photoinitiator and photoinhibitor Technologies are generally described for a photoresist and methods and systems effective to form a pattern in a photoresist on a substrate. In some examples, the photoresist includes a resin, a photoinitiator and a photoinhibitor. The photoinitiator may be effective to generate a first reactant upon the absorption of at least one photon of a particular wavelength of light. The first reactant may be effective to render the resin soluble or insoluble in a photoresist developer. The photoinhibitor may be effective to generate a second reactant upon the absorption of at least one photon of the particular wavelength of light. The second reactant may be effective to inhibit the first reactant.
US08580478B2	Latent acids and their use The invention pertains to a compound generating an acid of the formula I or II, for instance corresponding sulfonium and iodonium salts, as well as corresponding sulfonyloximes wherein X is CH2 or CO; Y is O, NR4, S, O(CO), O(CO)O, O(CO)NR4, OSO2, O(CS), or O(CS)NR4; R1 is for example C1-C18alkyl, C1-C10haloalkyl, C2-C12alkenyl, C4-C30cycloalkenyl, phenyl-C1-C3-alkyl, C3-C30cycloalkyl, C3-C30cycloalkyl-C1-C18alkyl, interrupted C2-C18alkyl, interrupted C3-C30cycloalkyl, interrupted C3-C30cycloalkyl-C1-C18alkyl, interrupted C4-C30cycloalkenyl, phenyl, naphthyl, anthracyl, phenanthryl, biphenylyl, fluorenyl or heteroaryl, all unsubstituted or are substituted; or R1 is NR12R13; R2 and R3 are for example C3-C30cycloalkylene, C3-C30cycloalkyl-C1-C18alkylene, C1-C18alkylene, C1-C10haloalkylene, C2-C12alkenylene, C4-C30cycloalkenylene, phenylene, naphthylene, anthracylene, phenanthrylene, biphenylene or heteroarylene; all unsubstituted or substituted; R4 is for example C3-C30cycloalkyl, C3-C30cycloalkyl-C1-C18alkyl, C1-C18alkyl, C1-C10haloalkyl, C2-C12alkenyl, C4-C30cycloalkenyl, phenyl-C1-C3-alkyl; R12 and R13 are for example C3-C30cycloalkyl, C3-C30cycloalkyl-C1-C18alkyl, C1-C18alkyl, C1-C10haloalkyl, C2-C12alkenyl, C4-C30cycloalkenyl, phenyl-C1-C3-alkyl, Ar, (CO)R15, (CO)OR15 or SO2R15; and Ar is phenyl, biphenylyl, fluorenyl, naphthyl, anthracyl, phenanthryl or heteroaryl, all unsubstituted or substituted.
US08580474B2	Electrostatic image developing carrier, electrostatic image developer, image-forming method, developer cartridge, process cartridge, and image forming apparatus An electrostatic image developing carrier includes a core particle and a coating layer on the core particle. The coating layer contains a resin having a crosslinked structure formed by using at least one compound selected from boric acid and boric acid derivatives.
US08580470B2	Charge control agent composition and toner utilizing the same A modified charge control agent composition comprising a metal compound (A) of aromatic hydroxycarboxylic acid bonded with a metal atom selected from a zirconium atom, a calcium atom, an aluminum atom, a chromium atom, a boron atom, and a zinc atom via at least one of an ionic bond, a covalent bond, and a coordinate bond; and at least one inorganic pigment (B), wherein the pigment (B) is contained in an amount of from 1 to 20 parts by mass in 100 parts by mass of the composition. The modified charge control agent composition exhibits a high charge-imparting effect, and an electrostatic image developing toner that contains the charge control agent composition will have a high electrostatic charge amount and a high environmental stability.
US08580468B2	Developer for electrostatic photography, process cartridge for image forming apparatus, image forming apparatus, and image forming method A developer for electrostatic photography, includes: a toner containing toner particles containing a colorant and a binder resin, and an external additive having a number average particle diameter of about 100 nm or more and about 800 nm or less; and rugged particles having a rate of ruggedness represented by formula (1) of about 30% or more and about 70% or less: Rate of Ruggedness=100−(Projected area/Envelope area)×100 (1).
US08580466B1	Optically semitransmissive film, photomask blank and photomask, and method for designing optically semitransmissive film A photomask blank includes a transparent substrate and a film containing at lease two layers formed on the transparent substrate, the two layers being a first layer with a phase difference Δθ1 and a second layer with a phase difference Δθ2. The phase difference Δθ1 is a phase difference between a light transmitted through the first layer and a light transmitted through an air distance equal to a thickness of the first layer, and the phase difference Δθ2 is a phase difference between a light transmitted through the second layer and a light transmitted through an air distance equal to a thickness of the second layer. A phase difference of the film containing at least two layers is from −30° to +30°. The first layer contains a material not to be etched during etching of the transparent substrate.
US08580465B2	Multilayer mirror for EUV lithography and process for its production Provided are a multilayer mirror for EUVL in which deterioration in reflectivity due to oxidation of a Ru protective layer is prevented, and a process for its production. A multilayer mirror for EUV lithography comprising a substrate, and a reflective layer for reflecting EUV light and a protective layer for protecting the reflective layer, formed in this order on the substrate, wherein the reflective layer is a Mo/Si multilayer reflective film, the protective layer is a Ru layer or a Ru compound layer, and an intermediate layer containing from 0.5 to 25 at % of nitrogen and from 75 to 99.5 at % of Si is formed between the reflective layer and the protective layer.
US08580464B2	Reverse saturable absorbtion sensitizers for optical data storage media and methods for use The invention relates generally to optical data storage media, and more specifically, to holographic storage media. In one embodiment, an optical storage medium composition includes a polymer matrix. Disposed within the polymer matrix is a reactant capable of undergoing a modification that alters the refractive index of the composition upon receiving an energy transfer from an excited sensitizer. A non-linear sensitizer is also disposed within the polymer matrix, and the sensitizer includes a metal-substituted subphthalocyanine (M-sub-PC) reverse saturable absorber configured to become excited upon exposure to light beyond an intensity threshold at approximately 405 nm and configured to transfer energy to the reactant.
US08580463B2	Reactants for optical data storage media and methods for use The present disclosure relates generally to optical data storage media, and more specifically, to holographic storage media. In one embodiment, an optical storage medium includes a polymer matrix having one or more polymer chains. The optical storage medium also includes a reverse saturable absorption (RSA) sensitizer disposed within the polymer matrix that is configured to become excited upon exposure to light having an intensity above an intensity threshold and configured to transfer energy to a reactant. The optical storage medium also includes a diphenyl cyclopropene (DPCP)-derivative reactant disposed within the polymer matrix and capable of undergoing a modification upon receiving an energy transfer from the excited sensitizer that changes a refractive index of the optical medium.
US08580462B2	Electrode catalyst material comprising carbon nano-fibers having catalyst particles on the surface and in the insides of the interior area and a fuel cell having the electrode catalyst material The carbon fibers of this invention is characterized in that irreducible inorganic material particles in a mean primary particle size below 500 nm and reducible inorganic material particles in a mean primary particle size below 500 nm were mixed by pulverizing and then, the mixture was heat treated under the reducing atmosphere and metal particles in a mean particle size below 1 μm were obtained, and the mixed powder of the thus obtained metal particles with the irreducible inorganic material particles are included in the carbon fibers.
US08580461B2	Anisotropic coefficient of thermal expansion lanthanum strontium manganite for solid oxide fuel cell cathode An anisotropic coefficient of thermal expansion (CTE) cathode of a solid oxide fuel cell (SOFC) is formed by placing a layer of perovskite powder between two platens, and sintering the layer while applying pressure to the platens, thereby forming the anisotropic CTE cathode. The perovskite can be lanthanum strontium manganite (LSM).
US08580459B2	Fuel cell with flow channel member for supplying reactive gas A fuel cell includes plural single cells and first sidewalls disposed on the outer side of a cell stack including the plural single cells. In the first sidewalls, holes for supplying the reactive gas to the cell stack are formed. The single cells are disposed in a row shape along a jetting direction (lateral direction) of the reactive gas jetted from the holes. The holes are formed such that a part of the reactive gas jetted from the holes brushes against at least the single cells disposed in positions closest to the first sidewalls and the remaining part of the reactive gas does not brush against the single cells disposed in the closest positions.
US08580457B2	Fuel cell stack sealed with encapsulating material and method of making the same The invention provides a fuel cell stack including a layer of encapsulating material disposed about the separator plate, MEA, and reactant manifold, wherein the reactant manifold is bounded at least in part by the encapsulating material. The fuel cell stack also includes a first opening through the plate body to the first face from the second face, and an open channel in the second face extending from the opening toward a periphery of the plate. The invention also provides a fuel cell stack having a first face including an opening for passage of a reactant therethrough, a first reactant flow field defined thereon, and a first raised surface formed thereon substantially surrounding the opening. The first raised surface is configured and adapted to mate with a second surface on a face of an adjacent plate to create a flow obstruction for encapsulating material.
US08580455B2	Crosslinked polybenzoxazines, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane Crosslinked polybenzoxazines obtained by crosslinking a monofunctional first benzoxazine monomer and a multifunctional second benzoxazine monomer with a crosslinkable compound, an electrolyte membrane including the same, a method of preparing the electrolyte membrane, a fuel cell including the electrolyte membrane having the crosslinked polybenzoxazines using the method. The crosslinked polybenzoxazines have strong acid trapping capability, improved mechanical properties, and excellent chemical stability as it does not melt in polyphosphoric acid. Even as the amount of impregnated proton carrier and the temperature are increased, mechanical and chemical stability is highly maintained, and thus the electrolyte membrane can be effectively used for fuel cells at a high temperature.
US08580450B2	Fuel cell system There is provided a fuel cell system. The fuel cell system includes a fuel cell generating electricity and heat by an electrochemical reaction between a fuel and air, a thermoelectric element converting heat, emitted from the fuel cell, into electrical energy, and a heat storage tank storing heat emitted from the thermoelectric element. The fuel cell system includes therein a configuration allowing for the conversion of heat, emitted from a fuel cell, into electricity or the utilization of heat, thereby minimizing the amount of heat that is released at the final stage. Therefore, a reduction in the size of a heat storage tank can be achieved, and the electricity conversion efficiency of a fuel cell can be improved.
US08580447B2	Fuel cell system and control method for the same An ECU estimates a dispersion among wet states of cells arranged in a lamination direction of a fuel cell. When it is determined that the dispersion among the wet states is equal to or exceed a threshold, the ECU controls a flow rate of a coolant, flow rates of gases, and pressures of gases to suppress the dispersion among the wet states below the threshold. The ECU controls the flow rate of the coolant with higher priority than the other parameters.
US08580444B2	Hydrogen discharge system for fuel cell system The present invention provides a hydrogen discharge system for a fuel cell system, which can ensure safety of a fuel cell vehicle by optimizing the dilution of hydrogen discharged from a fuel cell during discharge and ensure silence of the vehicle by reducing noise generated during discharge.For this purpose, the present invention provides a hydrogen discharge system for a fuel cell system including a purge valve for purging hydrogen discharged from a fuel electrode of a fuel cell stack, the hydrogen discharge system including: an ejector mounted to a hydrogen purge line extending from the purge valve to introduce air from the outside; and a post-treatment system connected to an exhaust line of the ejector to remove hydrogen discharged therethrough.
US08580442B2	Fuel cell system and method of repairing electrolyte membrane thereof A fuel cell system of the present invention includes: a fuel cell stack (1) composed by stacking a plurality of single cells, each single cell having: a membrane electrode assembly in which electrode catalyst layers (3) and gas diffusion layers (4) are disposed on both surfaces of an electrolyte membrane (2) formed of a gel electrolyte with a sol-gel phase transition temperature; and separators (5) disposed on both sides of the membrane electrode assembly; and a temperature adjusting apparatus (12) which adjusts a temperature of the electrolyte membrane in the single cell. In such a way, a defect such as a pinhole that has occurred in the electrolyte membrane (2) can be solved.
US08580433B2	Titanium oxide-based compound for electrode and lithium secondary battery using the same The present invention provides a novel titanium-based composite oxide being usable as an electrode material for a lithium secondary battery and having a high capacity and an excellent cycle stability, a method for producing the same and a lithium secondary battery using the titanium-based composite oxide. Disclosed is a compound obtained by compositing titanium oxide with elements other than titanium, specifically a titanium-based composite oxide wherein the relevant chemical formula is Ti(1-x)MxOy, M is the element Nb or the element P, or a combination of these two elements in an optional ratio therebetween, x is such that 0
US08580430B2	Battery structures, self-organizing structures, and related methods An energy storage device includes a first electrode comprising a first material and a second electrode comprising a second material, at least a portion of the first and second materials forming an interpenetrating network when dispersed in an electrolyte, the electrolyte, the first material and the second material are selected so that the first and second materials exert a repelling force on each other when combined. An electrochemical device, includes a first electrode in electrical communication with a first current collector; a second electrode in electrical communication with a second current collector; and an ionically conductive medium in ionic contact with said first and second electrodes, wherein at least a portion of the first and second electrodes form an interpenetrating network and wherein at least one of the first and second electrodes comprises an electrode structure providing two or more pathways to its current collector.
US08580429B2	Non-aqueous electrolyte for a lithium battery, lithium battery wherein said electrolyte is used, and hydroxy-acid derivative for use in said electrolyte Disclosed are (1) a nonaqueous electrolytic solution for lithium battery comprising an electrolyte dissolved in a nonaqueous solvent, which contains at least one hydroxy acid derivative compound represented by the formulae (I) and (II) in an amount of from 0.01 to 10% by mass of the nonaqueous electrolytic solution, and which can improve the low-temperature and high-temperature cycle property thereof (wherein R1 represents an alkyl group having from 1 to 6 carbon atoms, an alkenyl group having from 2 to 6 carbon atoms, or an alkynyl group having from 3 to 6 carbon atoms, R2 represents a sulfonyl group or a formyl group, R3 and R4 each represent a hydrogen atom or a methyl group); (2) a lithium battery comprising a positive electrode, a negative electrode and a nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, wherein the nonaqueous electrolytic solution contains at least one hydroxy acid derivative compound represented by the above formulae (I) and (II) in an amount of from 0.01 to 10% by mass of the nonaqueous electrolytic solution; and (3) a hydroxy acid derivative compound represented by the following formula (III) or (IV) (wherein R6 represents an alkenyl group having from 2 to 6 carbon atoms, or an alkynyl group having from 3 to 6 carbon atoms, R7 represents a sulfonyl group or a formyl group, and R8 and R9 each represent a hydrogen atom or a methyl group).
US08580424B2	Rechargeable battery A rechargeable battery includes a can having an open portion in an upper region and accommodates a power generating unit. A flexible plate is installed in the opening portion, the flexible plate being connected to an electrode of the power generating unit and flexing when the internal pressure of the rechargeable battery rises above an allowable range. A terminal cap is arranged on the flexible plate, electrically connected to the flexible plate, and has an insulating portion on a bottom surface. An insulating substrate is arranged between the flexible plate and the terminal cap and has a rupture portion that is broken when the flexible plate flexes beyond an allowable range. Upon breaking the broken ends of the insulating substrate directly contact the insulating portion of the terminal cap so that the insulating substrate is electrically disconnected from the terminal cap. Additionally, a gasket is installed between edges of the flexible plate, the insulating substrate, and the terminal cap plate and an inner wall of the opening portion to insulate the flexible plate, the insulating substrate, and the terminal cap from the can.
US08580416B2	Electronic device with battery latching assembly An electronic device includes a battery, a main body, and at least one latching assembly. At least one sidewall of the battery defines a positioning hole. The main body defines a battery compartment to receive the battery. The battery compartment includes an opening and at least one first sidewall adjacent to the opening. Each of the at least one latching assembly includes an elastic latching member, a resisting member, and a button. The elastic latching member is mounted in the first sidewall and partially received in the battery compartment. The resisting member is moveably mounted in the first sidewall and abuts the elastic latching member. The button is mounted in the main body and abuts the resisting member.
US08580414B2	Micro gap flow through electrochemical devices with self adjusting reactive surfaces Contemplated electrochemical devices and methods include an electrolyte flow path in which substantially all of the electrolyte has laminar flow. A segmented electrode contacts the electrolyte, and each of the segments in the segmented electrode is preferably coupled to a control device to provide control over the flow of current to and/or from the electrolyte. Thus, it should be appreciated that the redox state of the electrolyte can be changed in a single-pass through the flow path, which effectively eliminates problems associated with mass transport phenomena and reduced current efficiency.
US08580407B2	Covering member for preventing erosion There is provided a covering member for preventing erosion that has a high erosion resistance, is resistant to repeated thermal shocks so as to have a long life, and has a particular color allowing visual inspection of the surface layer for degradation.A covering member to be applied to a substrate made of an iron material or the like that will be eroded by contact with molten aluminum includes a Cr metal film as the lowest layer, a b layer formed of a CrN film, an intermediate layer, and an a layer formed of a TiSiN film, stacked in this order on the substrate. The intermediate layer includes layered films composed of the b layers and the a layers alternately stacked on top of one another.
US08580404B2	Triphenylene hosts in phosphorescent light emitting diodes An organic emissive layer is provided. Also provided is a device in which the organic emissive layer is disposed between an anode and a cathode. The organic emissive layer includes a phosphorescent material and triphenylene compound or a compound having a repeat unit having a triphenylene moiety. The triphenylene is optionally substituted. The substituents may be the same or different and each is selected from the group consisting of alkyl, aryl, fused aryl, substituted aryl, alkenyl, alkynyl, and heteroalkyl. Triphenylene compounds are also provided.
US08580396B2	Carbazole derivatives and organic light-emitting diode device using the same The present invention relates to novel carbazole derivatives and an organic light-emitting diode device using the same. These carbazole derivatives can simultaneously or singly be used as a hole transporting layer, a host or guest of an emitting layer or an electron transporting layer of an organic light-emitting diode device.
US08580391B2	Material for organic electroluminescence devices and organic electroluminescence device using the material A material for organic electroluminescence devices comprising a compound in which a heterocyclic group having nitrogen is bonded to an arylcarbazolyl group or a carbazolylalkylene group and an organic electroluminescence device comprising an anode, a cathode and an organic thin film layer comprising at least one layer and disposed between the anode and the cathode, wherein at least one layer in the organic thin film layer comprises the material for organic electroluminescence devices described above. The material can provide an organic electro-luminescence device emitting bluish light with a high purity of color. The organic electroluminescence device uses the material.
US08580390B2	Rolled copper foil or electrolytic copper foil for electronic circuit, and method of forming electronic circuit using same Provided is a rolled copper foil or electrolytic copper foil for an electronic circuit to be used for forming a circuit by etching, wherein the copper foil comprises a heat resistance layer composed of zinc or zinc alloy or its oxide formed on an etching side of the rolled copper foil or electrolytic copper foil, and a layer of nickel or nickel alloy, which is a metal or alloy with a lower etching rate than copper, formed on the heat resistance layer. This invention aims to prevent sagging caused by the etching, to form a uniform circuit having the intended circuit width, and to shorten the time of forming a circuit by etching as much as possible, when forming a circuit by etching a copper foil of the copper-clad laminate; and also aims to make the thickness of the nickel or nickel alloy layer as thin as possible, to inhibit oxidation when exposed to heat, to prevent tarnish (discoloration) known as “YAKE”, to improve the etching properties in pattern etching, and to prevent the occurrence of short circuits and defects in the circuit width.
US08580386B2	Laminate comprising curable epoxy film layer comprising a di-isoimide and process for preparing same The present invention deals with a laminate useful for forming fully encapsulated flexible printed wiring boards. The laminate comprises a dielectric substrate coated with a curable composition comprising an epoxy and a novel aromatic di-isoimide chemical compound. The curable composition provides the benefit of thermal latency, improving shelf-life, and reducing premature curing during processing. Fully encapsulated printed wiring boards are also disclosed.
US08580385B2	Multilayer coating film-forming method An object to be achieved by the present invention is to provide a method capable of forming a multilayer coating film having excellent smoothness, distinctness of image, and chipping resistance, by a 3-coat 1-bake process comprising successively applying an aqueous first colored coating composition, an aqueous second colored coating composition, and a clear coating composition to a substrate, and heat-curing the resulting three layers of the multilayer coating film all at once. The present invention provides a method for forming a multilayer coating film, which employs a 3-coat 1-bake process comprising sequentially applying an aqueous first colored coating composition (X), an aqueous second colored coating composition (Y), and a clear coating composition (Z) on a substrate; and heat-curing the resulting three layers of the multilayer coating film all at once, wherein the aqueous first colored coating composition (X) contains an acrylic resin (A), a curing agent (B), and a urethane resin emulsion (C), and a first colored coating film formed from the aqueous first colored coating composition (X) has a water swelling rate of 100% or less and an organic solvent swelling rate of 300% or less.
US08580382B2	Coated metal pigment, method for production of the same, and coating composition containing the same Provided are a coated metal pigment which can satisfy both the coating stability in use as an aqueous coating, i.e., water resistance, and the chemical resistance of coating films produced by application thereof at practically satisfactory levels; a method for producing the same; and an aqueous coating containing the same. The invention relates to a coated metal pigment including a metal pigment and a composite coating layer, wherein the composite coating layer includes an adhesion layer which is disposed on the surface of the metal pigment either in contact with the metal pigment or at an interposition of another layer and contains polysiloxane and/or silica, and a resin layer which is disposed on the surface of the adhesion layer either in contact with the adhesion layer or at an interposition of another layer.
US08580377B2	Laminated polyester film and solar panel made thereof This invention discloses a laminated film comprising two thermoplastic polyester outer layers of identical polytrimethylene terephthalates, different polytrimethylene terephthalates, identical blends of polytrimethylene terephthalate or different blends of polytrimethylene terephthalate and a middle layer selected from a metal foil, polyethylene-vinyl acetate, and a thermoplastic polymer comprising thermoplastic polyester different from the thermoplastic polyester of the two outer layers, wherein the middle layer is laminated between the two outer layers. This invention also discloses a solar panel comprising a back sheet made of the laminated film.
US08580376B2	Cutting tool Provided is a cutting tool which comprises a sintered cermet having high toughness and thermal shock resistance. The cutting tool, namely a tip 1, comprises a sintered cermet comprising: a hard phase 11 comprising one or more selected from among carbides, nitrides, and carbonitrides which comprise mainly Ti; and a binder phase 14 comprising mainly at least one of Co and Ni. The tip 1 has a cutting edge 4 lying along an intersecting ridge portion between a rake face 2 and a flank face 3, and a nose 5. The hard phase 11 comprises a first hard phase 12 and a second hard phase 13. When a residual stress is measured on the rake face 2 by 2D method, a residual stress σ11[1r] of the first hard phase 12 in a direction (σ11 direction), which is parallel to the rake face 2 and goes from the center of the rake face 2 to the nose being the closest to a measuring point, is 50 MPa or below in terms of compressive stress (σ11[1r]=−50 to 0 MPa), and a residual stress σ11[2r] of the second hard phase 13 in the σ11 direction is 150 MPa or above in terms of compressive stress (σ11[2r]≦−150 MPa).
US08580375B2	Soy composite materials comprising a reducing sugar and methods of making the same The present invention provides composite materials derived from formaldehyde-free aqueous binder compositions comprising defatted soy flour of no greater than 43 micron mesh particle size, polymer particles of at least one emulsion (co)polymer, and one or more reducing sugar. Also provided are methods of making and using composite materials containing the formaldehyde-free binder compositions.
US08580371B2	Self-cleaning superhydrophobic surface A superhydrophobic structure that may have a titanium substrate and nanoporous titanium oxide layer grown on the titanium substrate by anodization. The titanium oxide layer may have a plurality of nano-tube structures that create a microscopically rough surface on the titanium substrate. A hydrophobic coating may be deposited over the titanium oxide layer to create a superhydrophobic surface on the titanium substrate. The titanium oxide layer may provide a photocatalytic reaction with oxygen in surrounding air to oxidize organic contaminants on the superhydrophobic surface.
US08580367B2	Adhesive optical film, method for manufacturing adhesive optical film and image display An adhesive layer included in an adhesive-type optical film forms a portion located on the inside of a edge line of an optical film.
US08580365B2	Synthetic resin bottle having a gradation pattern, and process for injection molding the preform for use in such a bottle The technical problem to be solved by the invention is to change the thickness of the colored resin layer of the preform gradually in the upward or downward direction, by utilizing a tendency of gradual decrease in the thickness of the colored resin layer caused by the flow of the main resin inside the preform mold when the main resin and the colored resin are injected into the mold. The objects of this invention is to provide a biaxially drawn, blow molded bottle having new decorativeness created in which sophisticated color gradations associated with color density are created in the body of this bottle. The means of accomplishing this object involves adjusting the injection pattern including the time of starting and ending the supply of the main resin and the colored resin, and pressure or velocity profiles, reducing the thickness of the colored resin layer in the multi-layered molten resin fluid gradually at an upstream or downstream point of the flow, injection-molding the preform in which a color-gradated portion associated with the thickness of the colored resin layer has been formed, and biaxially drawing and blow molding this preform into a bottle having a color-gradated portion associated with the color density or color shade created on the body of the bottle.
US08580364B2	Cured-in-place liner material and methods and systems for manufacture A liner tube for repairing existing pipes is provided. The liner tube is sufficient flexible to lie substantially flat under its own weight thereby defining an upper portion and a lower portion. The liner tube includes an inner layer, an outer layer disposed around the inner layer, a first intermediate layer disposed between the inner layer and the outer layer, the first intermediate layer being wrapped around the inner layer to overlap itself and define a first overlap portion in the upper portion, and a second intermediate layer disposed between the first intermediate layer and the outer layer, the second intermediate layer being wrapped around the first intermediate layer to overlap itself and define a second overlap portion in the lower portion. The first and second intermediate layers include a porous material and the inner layer includes material substantially impermeable to liquids. Systems used to manufacture the liner tube are also provided. These systems include a stringer apparatus for inserting a string into a spool of flexible tubing, an assembler apparatus for folding the layers of the liner tube and an impregnator apparatus for impregnating intermediate layers of the liner tube with resin.
US08580362B2	Silicone products and methods for making silicone products The present invention relates to a silicone product comprising a single or double elastic material which is covered along at least one surface with an adhesive or non-adhesive silicone-gel, wherein the elastic material is woven or knitted and comprises polyamide or polyester.
US08580360B2	Thermal transfer sheet and ink ribbon A thermal transfer sheet includes a protective layer and an adhesive layer which are laminated on a sheet base material in that order, the protective layer including a binder resin containing fine particles. The particle diameter of the fine particles is 0.9 to 2.8 times the thickness of the protective layer.
US08580358B2	Cellulose ester film, polarizing plate for in-plane-switching mode display and in-plane-switching mode display using the cellulose ester film A cellulose ester film containing a polyester represented by Formula (1) or (2), wherein an in-plane retardation value (Ro) is 0 to 5 nm and a retardation value in a thickness direction (Rt) is −20 to 10 nm, Ro and Rt being measured at 23° C. and 55% RH: B1-(G-A-)mG-B1 Formula (1) wherein B1: monocarboxylic acid, G: dihydric alcohol, A: dibasic acid, B1, G and A contain no aromatic ring, m: repeat number, plural B1 may be the same or different, and plural G may be the same or different; and B2-(A-G-)nA-B2 Formula (2) wherein B2: monoalcohol, G: dihydric alcohol, A: dibasic acid, provided that none of B2, G and A contains an aromatic ring, n: repeat number, plural B2 may be the same or different, and plural G may be the same or different.
US08580357B2	Liquid crystal display device A liquid crystal display device includes: a pair of substrates, at least one of which is transparent; a liquid crystal layer placed between the pair of substrates; an electrode group, formed on at least one of the pair of substrates, for applying an electric field to the liquid crystal layer; and an alignment control film placed on at least one of the pair of substrates, in which the alignment control film is formed of polyimide and a precursor of the polyimide, each of the polyimide and the precursor of the polyimide contains, as a material, a specific cyclobutanetetracarboxylic acid dianhydride derivative and aromatic diamine, and the alignment control film is provided with alignment capability by photo-alignment treatment.
US08580356B2	Method of fabricating alignment layer for liquid crystal display device A method of fabricating an alignment layer for a liquid crystal display device includes forming an alignment material layer on a substrate by coating an alignment material, irradiating UV rays onto the alignment material layer and pre-baking the alignment material layer; and post-baking the alignment material layer.
US08580355B2	Method for thin layer deposition The subject of the invention is a process for obtaining a material comprising a substrate and at least one at least partially crystalline titanium-oxide-based thin film deposited on a first side of said substrate, said process comprising the following steps: said at least one titanium-oxide-based thin film is deposited; said at least one titanium-oxide-based thin film is subjected to a crystallization treatment, supplying energy capable of raising each point of said at least one titanium-oxide-based thin film to a temperature of at least 300° C. while maintaining a temperature not exceeding 150° C. at any point on the opposite side of said substrate to said first side; said crystallization treatment being preceded by a deposition step, in which an energy-providing film is deposited above and/or below said titanium-oxide-based thin film, said energy-providing film being capable of absorbing the energy supplied during said crystallization treatment more effectively than said at least one titanium oxide film and/or of creating additional energy during said crystallization treatment, and of transmitting at least some of said energy to said at least one titanium-oxide-based thin film during said crystallization treatment.
US08580352B2	Touch screen substrate and method of manufacturing a touch screen substrate A method of manufacturing a touch screen substrate includes forming a sensing electrode on a substrate, spraying a first ink and a second ink having a same amount of ink as the first ink to respectively form a first ink droplet and a second ink droplet on a light blocking region of the substrate, and irradiating a first light upon the first ink droplet to form a first spacer having a first height and a second light upon the second ink droplet to form a second spacer having a second height lower than the first height. A total energy of the first light irradiated upon the first ink droplet differs from a total energy of the second light irradiated upon the second ink droplet, and the second spacer makes contact with the sensing electrode.
US08580351B2	Hydrophobic coating of condensers in the fitted state A method for producing a condenser for a thermal power plant is provided. First, the production method includes fitting a condenser tube in a carrier for a condenser tube bundle of the condenser. Then, the fitted condenser tube is coated with a hydrophobic coating. Coating the fitted condenser tube includes positioning a spray mechanism on the carrier, spraying on the hydrophobic coating using a spray mechanism, and moving the spray mechanism during spraying at a uniform rate. In another aspect, a device is provided. Also, a condenser is provided in an aspect.
US08580339B2	Coating process for the coating of an interior of a pipework system as well as a sub-distributor and a working equipment for the treatment of a pipework system A coating process for the interior of a pipework system, which includes a subsystem having a first part-system and a second part-system coupled to the first part-system, wherein the part-system can be pressurized by a pressure difference via a first connection of the first part-system and via a second connection of the second part-system, and wherein the first connection of the second part-system is identical to the second connection of the first part-system. In a second process step the first part-system is pressurized in such a way that a fluid-flow of the coating material is established through the first part-system and then the first connection of the second part-system is pressurized after the coating material leaves the second connection of the first part-system so that the first part-system and the second part-system is consecutively fed with the coating material.
US08580336B2	Method of making heat treated coated article using diamond-like carbon (DLC) coating and protective film A method of making a heat treated coated article includes forming at least one layer comprising diamond-like carbon (DLC) on a glass substrate, and forming a removable protective film on the glass substrate over at least the layer comprising DLC. The removable protective film includes first and second inorganic layers, the first inorganic layer comprising zinc oxide and nitrogen and being located between the layer comprising DLC and the second inorganic layer. The glass substrate may be heat treated so that during the heat treating the protective film prevents significant burnoff of the layer comprising DLC.
US08580335B2	Method for discharging liquid body, method for manufacturing color filter, and method for manufacturing organic EL device A method for discharging a liquid body includes: discharging the liquid body to a discharged region from a plurality of nozzles while a plurality of droplet discharge heads having a nozzle line having the plurality of nozzles that discharge the liquid body as droplets and are arranged in a linear manner, and a substrate including a plurality of discharged regions having a nearly rectangular shape are relatively moved in a main scan direction that is nearly orthogonal to an arrangement direction of the droplet discharge heads. In the method, the plurality of discharged regions are composed of a first discharged region and a second discharged region. The first discharged region is disposed on the substrate to set a long side thereof along a certain direction, and the second discharged region has a smaller area than the first discharged region and is disposed to set a long side thereof nearly orthogonal to the long side of the first discharged region. Further, the first discharged region is disposed to set the long side thereof along the main scan direction in the discharging.
US08580332B2	Thin-film battery methods for complexity reduction Thin-film battery methods for complexity reduction are described. Processing equipment arrangements suitable to support thin-film battery methods for complexity reduction are also described. Cluster tools to support thin-film battery methods for complexity reduction are also described.
US08580331B2	Digital manufacture of an electrical circuit Electrographic printing of one or more multi-channeled layers produces a specialty item. Such electrographic printing includes forming a desired print image, electrographically, on a receiver member utilizing predetermined sized marking particles; and, where desired, forming one or more final multi-channeled layers utilizing marking particles of a predetermined size or size distribution.
US08580327B2	Heat stable, fat-based confections and methods of making same New coated food products are provided. The products comprise a center food piece such as a nutmeat or cereal piece, and a coating surrounding the center food piece. The coating can be flavored with flavorings such as cheese, chocolate, or fruit. The coating comprises a substantially homogeneous mixture of a fat-based composition and a particulate material, which results in a stable coating that can tolerate higher temperatures when compared to prior art products while also having 50% or less of the fat content of prior art coatings.
US08580324B2	Fermentation process Provided is a fermentation process wherein green ripe uncured vanilla beans are incubated with bacillus subtilis in isolated form to convert glucovanillin to vanillin while consistently forming a fully developed well-balanced vanilla aroma without off-notes.
US08580323B2	Method for making lactose removed milk A method for removing lactose from milk comprising the steps of precipitation, ultrafiltration, re-dissolving, mixing, and restoration, with or without a step of degreasing prior to precipitation. The lactose-removed diary product can be liquid milk, milk powder, or combined with other products to make sugar-free or low-sugar healthy food. The milk used in the method can be milk from any mammals or milk obtained by dissolving milk powder in drinking water.
US08580320B2	Cosmetic preparation and method for preparing the same The present invention relates to the use of dedifferentiated plant cells in cosmetic preparations for protecting of stem cells against intrinsic and extrinsic stress factors, in particular for promoting proliferation of stem cells and for protecting them against apoptosis. In particular, the invention relates to the use of dedifferentiated plant cells from fruits of Malus domestica (Apple) cultivar Uttwiler Spaetlauber. Further, the invention relates to a method for cultivating of dedifferentiated plant cells, as well as to the preparation of extracts of plant cell cultures which are suitable for such applications.
US08580319B2	Topical compositions comprising fermented extracts of traditional chinese medicinal (TCM) ingredients, and methods of making and using same The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products.
US08580318B2	Natural water soluble extracts for the inhibition of alpha-1-adrenergic receptors The present invention discloses therapeutic natural products, in particular plant extracts effective in treating and preventing urinary tract disorders, and method for obtaining said extracts. In particular, the present invention discloses a water-soluble alcoholic extract of Opuntia ficus-indica flower (NABIA extract), a component thereof (NABIA fraction) or any mixture of components thereof, which is substantially free of non water-soluble residues, and exhibits an effective alpha-1-adrenergic receptor blocking activity. Further are disclosed methods of preparing this extract and methods of inhibiting alpha-1-adrenergic receptors and/or 5-alpha-reductase, as well as of treating medical conditions associated therewith, such as urinary tract disorders.
US08580316B2	Immune stimulatory infant nutrition A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein is provided. The composition has a weight ratio of casein to whey between 1:1 to 1:2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. Methods of treatment by administering the composition are also provided.
US08580309B2	Antimicrobial mixtures The present invention presents a mixture comprising charge-stabilized metallic nanoparticles and a photosensitizer, a method for making such mixture, and a method of using such mixture for killing or preventing the growth of microbes.
US08580306B2	Particles for use in a pharmaceutical composition The invention provides a method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2 μm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerolization of a dry, powder in a dry powder inhaler.
US08580305B2	Tablet quickly melting in oral cavity The object of the present invention is to provide, as a solid preparation for making it easy to take, thus improving patient's compliance etc., an intraorally rapidly disintegrating tablet which can be produced easily without any particular problem by a usual method of producing tablets with a usual tabletting machine, has practically unproblematic hardness, and disintegrate rapidly in the oral cavity. This tablet is produced by tabletting cores coated with a pharmaceutical disintegrating agent, wherein the core is a granule containing a water-soluble medicament or containing a medicament and a sugar.
US08580304B2	Pharmaceutical composition Disclosed are novel pharmaceutical compositions containing N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide dimethyl sulfoxide solvate, methods of using the compositions in therapy and processes for preparing the same.
US08580302B2	Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures The present invention relates to a pharmaceutical composition in a solid unit dosage form for oral administration in a human or lower animal comprising: a. a safe and effective amount of a therapeutically active agent; b. an inner coating layer selected from the group consisting of poly(methacrylic acid, methyl methacrylate) 1:2, poly(methacrylic acid, methyl methacrylate) 1:1, and mixtures thereof; and c. an outer coating layer comprising an enteric polymer or film coating material; wherein the inner coating layer is not the same as the outer coating layer; wherein if the inner coating layer is poly(methacrylic acid, methyl methacrylate) 1:1 then the outer coating layer is not poly(methacrylic acid, methyl methacrylate) 1:2 or is not a mixture of poly(methacrylic acid, methyl methacrylate) 1:1 and poly(methacrylic acid, methyl methacrylate) 1:2; and wherein the inner coating layer and the outer coating layer do not contain any therapeutically active agent. This invention further relates to a method of maintaining the desired site of delivery of a therapeutic agent in the gastrointestinal tract by administering the above compositions to a human or lower animal.
US08580301B2	Psychostimulant containing pharmaceutical composition The present invention is directed to a psychostimulant containing pharmaceutical composition comprising an enteric coating and showing a sustained release of said psychostimulant in vivo. The invention is further directed to the use of said pharmaceutical composition in the treatment of the Attention Deficit Hyperactivity Disorder (ADHD) and comorbidities, narcolepsy, fatigue and/or cognitive decline associated with systemic diseases such as acquired immunodeficiency syndrome or oncological diseases. Additionally, the present invention provides a method for the manufacture of said pharmaceutical composition.
US08580300B2	Pharmaceutical formulation for treating the upper digestive tract The invention relates to an effervescent tablet for preparing a mouth rinsing solution, wherein the effervescent tablet exhibits a high release rate of budesonide. A high availability of the active ingredient during use as a mouth rinsing solution on the inflamed mucosa of the upper digestive tract is thereby achieved. The advantage of the formulation according to the invention lies in the bioavailability comparable to oral forms of administration, which allows the formulation to be used safely over an extended period of time.
US08580298B2	Low dose topiramate/phentermine composition and methods of use thereof A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate.
US08580294B2	Platinum-catalyzed intravaginal rings The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of an antimicrobial compound, e.g., Dapivirine, to a human. The intravaginal rings of the invention address previous stability issues by utilizing a platinum catalyst (e.g., in the form of a platinum-siloxane complex) for the cross-linking reaction. The vaginal rings surprisingly achieve relatively high and steady release rates in vivo with a matrix ring containing a relatively small loading dose. While the matrix rings of the present invention have in vivo the steady release rates associated with reservoir rings, they are easier and less expensive to manufacture. The present invention also provides methods of blocking DNA polymerization by an HIV reverse transcriptase enzyme, methods of preventing HIV infection in a female human, methods of treating HIV infection in a female human, and methods of preparing platinum-catalyzed intravaginal rings.
US08580291B2	Fibrous composite for tissue engineering Provided are fibrous composites prepared by methods of the present invention, comprising oxides and biodegradable polymers, in which the fibers are made of aerogel-like oxide materials having nanometer-sized pores. The fibrous composition advantageously has, at least, the following characteristics: (i) a very high nanoporous surface area, which also permits nucleation of crystallites; (ii) mesoporous/macroporous interspacial networks between the fibers, providing high bioactivity and a high transport rate; (iii) macropores for natural bone-like tissue growth; (iv) good mechanical properties for handling and for implant support; and (v) biodegradability for implant dissolution and time-variable mechanical properties. Further provided are methods for using the bioactive biodegradable fibrous composites as osteogenic composite materials for tissue engineering, tissue re-growth, bone implants, and bone repair, and/or for the delivery of drugs or therapeutic compounds.
US08580288B2	Agricultural or horticultural fungicide composition and its use for controlling plant pathogens The present invention provides a composition in which a fungicidal effect against a cultivated crop infected by a plant pathogen is stable and highly active. An excellent agricultural or horticultural fungicide composition for controlling a plant pathogen is provided by using (a) at least one imidazole compound represented by formula (I): wherein R represents a C1-6 alkyl group or a C1-6 alkoxy group; and n represents an integer of 1 to 5 and (b) folpet as active ingredients; by combination as compared to a single use of each compound, and a plant pathogen is thereby controlled.
US08580283B2	Gel-based lipstick having improved rheology Gel-based lipstick compositions are disclosed comprising an ester terminated poly(ester-amide) (ETPEA) polymeric gellant, a first wax component having a melting point above the sol-gel transition temperature of the ETPEA gellant, a second wax compositions having a melting point equal to of below the sol-gel transition temperature of the ETPEA gellant, optionally a silicone T-resin co-gellent, and one or more oils capable of forming a gel with the ETPEA gellant. The gel compositions are solid or semi-solid at room temperature and are capable of being molded into self-supporting sticks. The disclosed gels provide high gloss films when applied to the lips and/or provide a rheology characterized by a high viscosity over repeated shear cycles.
US08580281B2	Medicated patch Provided is a medicated patch containing a medicinal agent and an adhesive base material and having an acid value of no greater than 28, where the medicinal agent is varenicline or a pharmaceutically acceptable salt of varenicline.
US08580276B2	Genetically stable recombinant modified vaccinia ankara (rMVA) vaccines and methods of preparation thereof A vaccine comprising an immunologically effective amount of recombinant modified vaccinia Ankara (rMVA) virus which is genetically stable after serial passage and produced by a) constructing a transfer plasmid vector comprising a modified H5 (mH5) promoter operably linked to a DNA sequence encoding a heterologous foreign protein antigen, wherein the expression of said DNA sequence is under the control of the mH5 promoter; b) generating rMVA virus by transfecting one or more plasmid vectors obtained from step a) into wild type MVA virus; c) identifying rMVA virus expressing one or more heterologous foreign protein antigens using one or more selection methods for serial passage; d) conducting serial passage; e) expanding an rMVA virus strain identified by step d); and f) purifying the rMVA viruses from step e) to form the vaccine. One embodiment is directed to a fusion cytomegalovirus (CMV) protein antigen comprising a nucleotide sequence encoding two or more antigenic portions of Immediate-Early Gene-1 or Immediate-Early Gene-2 (IEfusion), wherein the antigenic portions elicit an immune response when expressed by a vaccine.
US08580275B2	Drug delivery product and methods The present invention provides a particulate delivery system comprising an extracted yeast cell wall comprising beta-glucan, a payload molecule and a payload trapping molecule. The invention further provides methods of making and methods of using the particulate delivery system.
US08580271B2	Detection kit containing a novel recombinant 15-kDA polypeptide useful for detecting human infection with Bartonella henselae Disclosed are the cloning and expression of a novel antigen of Bartonella henselae. The recombinant polypeptide is found to be highly immunogenic and is useful as a diagnostic test antigen. The polypeptide of the present invention provides the basis of a diagnostic assay that is sensitive, rapid and accurate diagnosis of infection with Bartonella henselae using patient's sera. Disclosed also are the ELISA for both IgG and IgM and allows diagnosis of early and late infection.
US08580264B2	Subcutaneously administered anti-IL-6 receptor antibody The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic JIA (sJIA), polyarticular course JIA (pcJIA), systemic sclerosis, or giant cell arteritis (GCA), with subcutaneously administered antibody that binds interleukin-6 receptor (anti-IL-6R antibody). In particular, it relates to identification of a fixed dose of anti-IL-6R antibody, e.g. tocilizumab, which is safe and effective for subcutaneous administration in patients with IL-6-mediated disorders. In addition, formulations and devices useful for subcutaneous administration of an anti-IL-6R antibody are disclosed.
US08580263B2	Anti-EGFR family antibodies, bispecific anti-EGFR family antibodies and methods of use thereof Anti-EGFR family member antibodies and bispecific antibodies comprising one or more anti-EGFR family member antibodies are disclosed. These antibodies can be used to advantage to specifically target forms of cancer associated with the overexpression of members of the EGFR protein family.
US08580262B2	Group B Streptococcus antigens Group B streptococcus (GBS) proteins and polynucleotides encoding them are disclosed. Said proteins are antigenic and therefore useful vaccine components for the prophylaxis or therapy of streptococcus infection in animals. Also disclosed are recombinant methods of producing the protein antigens as well as diagnostic assays for detecting streptococcus bacterial infection.
US08580259B2	Human monoclonal antibodies to BTLA and methods of use The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically bind to BTLA with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the disclosure are also provided. The disclosure also provides methods for detecting BTLA, as well as methods for treating various diseases, including cancer and infectious diseases, using anti-BTLA antibodies.
US08580258B2	Treatment of tumors using specific anti-L1 antibody The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment.
US08580250B2	Botulinum toxin compositions A high potency botulinum toxin pharmaceutical composition comprising two excipients (such as albumin and sodium chloride) in a weight to weight ratio of between about 1 and about 100.
US08580245B2	Compositions and methods for treating and preventing cardiomyopathy and heart disease The present invention relates to compositions and methods for treating and preventing heart disease. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing heart disease (e.g., in subjects with muscular dystrophy) and for treating cells and tissue damage caused by ischemia and cell death (e.g., for treating dystrophin-deficient cells (e.g., myocytes)).
US08580244B2	Cyclodextrin-based polymers for therapeutics delivery The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
US08580243B2	Cyclodextrin-based polymers for therapeutics delivery The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
US08580242B2	Cyclodextrin-based polymers for therapeutics delivery The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
US08580229B2	Amyloid imaging as a surrogate marker for efficacy of anti-amyloid therapies The present method for determining the efficacy of therapy in the treatment of amyloidosis involves administering to a patient in need thereof a compound of formula (I) or Formula (II) or structures 1-45 and imaging the patient. After said imaging, at least one anti-amyloid agent is administered to said patient. Then, an effective amount of a compound of formula (I) or Formula (II) or structures 1-45 is administered to the patient and the patient is imaged again. Finally, baseline levels of amyloid deposition in the patient before treatment with the anti-amyloid agent are compared with levels of amyloid deposition in the patient following treatment with the anti-amyloid agent.
US08580222B2	Process for remediation of plastic waste A single step process for degrading plastic waste by converting the plastic waste into carbonaceous products via thermal decomposition of the plastic waste by placing the plastic waste into a reactor, heating the plastic waste under an inert or air atmosphere until the temperature of about 700° C. is achieved, allowing the reactor to cool down, and recovering the resulting decomposition products therefrom. The decomposition products that this process yields are carbonaceous materials, and more specifically carbon nanotubes having a partially filled core (encapsulated) adjacent to one end of the nanotube. Additionally, in the presence of a transition metal compound, this thermal decomposition process produces multi-walled carbon nanotubes.
US08580218B2	Method of purifying silicon utilizing cascading process The present invention relates to a method of purifying a material using a metallic solvent. The present invention includes a method of purifying silicon utilizing a cascade process. In a cascade process, as the silicon moves through the purification process, it contacts increasingly pure solvent metal that is moving through the process in an opposite direction.
US08580213B2	Method for recovering nickel from sulfuric acid aqueous solution A method for recovering nickel from sulfuric acid aqueous solution, for recovering nickel in an effectively utilizable form as a raw material of nickel industry material, by separating efficiently impurity elements of iron, aluminum, manganese, etc., from the sulfuric acid aqueous solution containing nickel and cobalt, and the impurity elements, iron, aluminum, manganese, etc. The method comprises the following steps: subject the sulfuric acid aqueous solution to oxidation neutralization treatment; then subject the solution to neutralization treatment, and separate and recover mixed hydroxides containing nickel and cobalt; subject the mixed hydroxides to dissolution treatment in a sulfuric acid solution having a concentration of equal to or higher than 50% by mass; subject the concentrated solution to solvent extraction treatment, using a phosphate ester-based acidic extraction agent; add a neutralizing agent to the resultant extraction residual liquid; subject the solution to the neutralization treatment, and separate and recover nickel hydroxide generated.
US08580210B2	Sample aspirating apparatus and sample analyzer A sample aspirating apparatus including a pipette which aspirates a sample, wherein the pipette is able to penetrate a cap of a capped container; a cap sensor which detects the cap of the capped container; a driving section which moves the pipette upward and downward; a crash sensor which detects a crash of the pipette with an obstacle; and a controller which controls the driving section to move the pipette, and stop the pipette when the crash sensor detects a crash by the pipette, wherein when aspirating a sample from a container after the cap sensor has detected a cap, the controller controls the driving section to move the pipette downward regardless of the detection by the crash sensor and thereby cause the pipette to penetrate the cap of the container. A sample analyzer which includes the above mentioned sample aspirating apparatus is also disclosed.
US08580208B2	Reactor and method for production of hydrogen sulphide The present invention describes a reactor (1) for continuously preparing hydrogen sulfide H2S from hydrogen and sulfur, comprising a distributor device (15) for distributing gaseous hydrogen in a sulfur melt (9) present at least in a lower part of the reactor. The distributor device (15) is arranged in the sulfur melt (9) and comprises a distributor plate (16) which is arranged in the reactor (1) and has an edge (17) extending downward and, if appropriate, has passage orifices (19). The hydrogen from a hydrogen bubble which forms below the distributor plate (16) is (for example through the passage orifices (19)) distributed in the sulfur melt (9) via the distributor plate (16).
US08580204B2	Fluidized bed reactor A fluidized bed reactor is disclosed. The fluidized bed reactor includes a reaction pipe comprising silicon particles provided therein; a flowing-gas supply unit configured to supply flowing gas comprising silicon elements to the silicon particles provided in the reaction pipe; and a heater unit configured to supply heat to an internal space of the reaction pipe, with a heater channel in which inert gas flows serially.
US08580199B2	Oxygen sensor and measuring method A sensor for measuring an oxygen content in a liquid or gaseous sample has first and second sensor sections (14a, 14b). The first sensor section (14a) can be brought into contact with the sample and has a luminescent indicator dye embedded in an oxygen-permeable first polymer matrix. The second sensor section (14b) is arranged adjacent to the first sensor section (14a) and includes the same dye embedded in an oxygen-impermeable second polymer matrix. A light guide (10) guides luminescence excitation light from a light source (31, 32) to the sensor sections (14a, 14b) and guides luminescence emission light from the sensor section (14a, 14b) to a detector (39).
US08580193B2	Method and device for pasteurizing a liquid product A method for pasteurizing a liquid product includes heating the liquid product to a pasteurization temperature, thereby killing micro-organisms, keeping it in a treatment chamber at the pasteurization temperature for a holding period, regulating a length of the treatment station based at least in part on its flow-rate, regulating a product volume within the treatment chamber by changing a level of a liquid product surface in the treatment chamber through, for example, addition and removal of sterile gas or vapor-forming medium in a partial chamber of the treatment chamber formed above the product surface, or changing a level of a product outlet in the treatment chamber.
US08580192B2	Sterilization of polymeric materials A method of sterilizing a polymeric material that is sensitive to radiation. The method includes the steps of applying at least one radiosensitizer to the polymeric material and irradiating the polymeric material with a suitable radiation at an effective dose and time to sterilize the polymeric material. Also disclosed is a method of enhancing the ability of a medical device to withstand sterilization by radiation and a bioabsorbable polymeric medical device.
US08580191B2	Brass alloys having superior stress corrosion resistance and manufacturing method thereof The present invention relates to a brass alloy having superior stress corrosion comprising: 59.0-64.0 wt % Cu, 0.6-1.2 wt % Fe, 0.6-1.0 wt % Mn, 0.4-1.0 wt % Bi, 0.6-1.4 wt % Sn, at least one element selected from Al, Cr and B, the balance being Zn and unavoidable impurities, wherein the content of Al is 0.1-0.8 wt %, the content of Cr is 0.01-0.1 wt %, the content of B is 0.001-0.02 wt %. The alloy according to the present invention does not contain toxic elements such as lead and antimony, has superior corrosion resistance and good cuttingability and is suitable for the accessories in the potable water supply systems produced by casting, forging and extruding.
US08580188B2	Method for producing a penetrator The invention relates to a method for producing a penetrator (10) from a tungsten heavy metal with a high fraction of tungsten and an outer sheath (7), which consists of a material that is more ductile in relation to the penetrator core (6). To produce a penetrator (10) of this type in a cost-effective manner, according to the invention a twin-hopper filling device, which corresponds to the dimensions of the penetrator core (6), is introduced concentrically into a compression mold (1) that corresponds to the outer dimensions of the penetrator (10). The inner pipe (3) is filled with a first tungsten powder blend with a high fraction of tungsten for producing the penetrator core (6), while the annular gap between the outer wall of the inner pipe and the inner wall of the compression mold (1) is filled with a second tungsten powder blend with a lower fraction of tungsten, (approximately between 85% and 91%), than the first powder blend. Once the inner pipe (3) has been removed from the compression mold (1), the powder blend is then compressed in the known manner to produce the penetrator (10), the compressed body is subsequently sintered and cold-formed and the penetrator slug is finally finished.
US08580184B2	Hollow fiber mat with soluble warps and method of making hollow fiber bundles A method of forming hollow fiber bundles includes the step of providing a mat having a plurality of hollow fibers forming a weft and a plurality of soluble fibers forming a warp. Each hollow fiber extends between a first side and an opposed second side of the mat. The mat is bundled so as to form a bundle with the first side of the mat defining a first end of the bundle and the second side of the mat defining a second end of the bundle. At least a portion of the bundle is potted so as to substantially fix a position of the hollow fibers relative to each other. The soluble fibers are at least partially dissolved so as to remove the soluble fibers from the bundle.
US08580182B2	Process of making a molded respirator A molded respirator is made from a monocomponent monolayer nonwoven web containing a bimodal mass fraction/fiber size mixture of intermingled continuous monocomponent polymeric microfibers and larger size fibers of the same polymeric composition. The respirator is a cup-shaped porous monocomponent monolayer matrix whose matrix fibers are bonded to one another at least some points of fiber intersection. The matrix has a King Stiffness greater than 1 N. The respirator may be formed without requiring stiffening layers, bicomponent fibers, or other reinforcement in the filter media layer.
US08580180B2	Polymeric stent polishing method and apparatus A method and apparatus for simultaneously polishing the inner and outer surfaces of an unpolished polymeric stent using a heat process. The unpolished stent can be mounted, for example, on a “spiral-mandrel,” a tubular helical structure with gaps in between a series of coils of the structure. Heat from a heat source can then applied to the spiral-mandrel at a range between the glass transition temperature and melting temperature of the polymer of the stent.
US08580179B2	Apparatus for moulding a part of a packaging container An apparatus for molding a thermoplastic package part(s) to an end portion of a container body includes inner and outer mold elements between which a mold cavity per package part is formed. At least one of these mold elements is at least partly freely suspended. When one package part is molded with the mold elements, plastic melt is injected in a first number ≧1 of points in the cavity, an island of plastic melt for each point is formed inside the cavity, and the distribution of the points causes a force center to pass through a surface defined by a parallel projection of each first number of islands on a plane orthogonal to a direction of the compression force, and when the first number >1, a second number of imaginary straight lines interconnecting a third number of parallel projections such that the surface is at its maximum.
US08580165B2	Method for manufacturing multiple-phase particle and apparatus for manufacturing multiple-phase particle Disclosed is a method of manufacturing a multiple-phase particle comprising preparing a channel whose outlet port is adapted to a first fluid, feeding a second fluid into the channel, the second fluid being higher in affinity to the outlet port as compared with the first fluid, feeding a third fluid into the channel, the third fluid being lower in affinity to the outlet port as compared with the second fluid, and introducing the third fluid into the second fluid in the channel while retaining the second fluid at the outlet port by an effect of the affinity of the second fluid, thereby entrapping the third fluid in the second fluid to form the multiple-phase particle.
US08580164B2	Method of manufacturing mold and method of forming optical film by mold A method of manufacturing a mold includes following steps. Providing a solution, which includes a solvent, a solute and a plurality of nanoparticles. Providing a first substrate. Spin coating the solution on the first substrate, and then vaporizing the solvent to form a first mold on the first substrate. Thus, an upper surface of the first mold has a plurality of first porous structures. The present invention further includes forming an optical film having protrusion patterns with the aforementioned mold.
US08580162B2	Method of directly molding ferrule on fiber optic cable A method of directly molding a fiber optic ferrule on an end of a fiber optic cable is disclosed. The method preferably includes stripping a cable jacket and/or a buffer layer from optical fibers of the fiber optic cable and trimming the optical fibers with a laser thereby creating trimmed ends on the optical fibers. The optical fibers and preferably a pin assembly are held near the end of the fiber optic cable by an optical fiber and pin locator. The optical fiber and pin locator can statically or dynamically hold and position the optical fibers and pin assembly. After the optical fibers and/or the pin assembly are positioned, a fixture is attached to the trimmed ends of the optical fibers and/or the pin assembly thereby preserving their relative position to each other. After the fixture is attached, the optical fiber and pin locator is removed, and the end of the fiber optic cable with the attached fixture is placed into a mold cavity. A molding material is injected into the mold cavity thereby overmolding a substantial portion of the end of the fiber optic cable and thereby creating a molded body of the fiber optic ferrule. After molding, the fixture is removed. The fixture preferably includes a thin film that is hardened on the trimmed ends of the optical fibers while the optical fiber and pin locator is attached.
US08580159B2	Ink for inkjet recording, ink set for inkjet recording, ink media set for inkjet recording, ink cartridge, inkjet recording method, and inkjet recording apparatus An ink for inkjet recording containing water, water-soluble organic solvent, water-dispersible resin, fluorochemical surfactant or derivative thereof, and coloring agent containing pigment, where the ink has a surface tension of 20-35 mN/m and viscosity of ≧5 mPa·s at 25° C., total amount of the water-dispersible resin and the coloring agent in the ink is 5-40% by mass, and mass ratio A/B of the water-dispersible resin A to the coloring agent B is 0.5-4, where the ink is applied to a recording medium containing a support containing cellulose pulp, and one or more barrier layers disposed on a face of the support, and where the barrier layer contains ≧30% by mass of inorganic pigment having refractive index of ≧1.5, excluding aluminum hydrate, and ≦10% by mass of inorganic pigment having a refractive index of <1.5.
US08580158B2	Methods of removing silicon dioxide Some embodiments include methods of removing silicon dioxide in which the silicon dioxide is exposed to a mixture that includes activated hydrogen and at least one primary, secondary, tertiary or quaternary ammonium halide. The mixture may also include one or more of thallium, BX3 and PQ3, where X and Q are halides. Some embodiments include methods of selectively etching undoped silicon dioxide relative to doped silicon dioxide, in which thallium is incorporated into the doped silicon dioxide prior to the etching. Some embodiments include compositions of matter containing silicon dioxide doped with thallium to a concentration of from about 1 weight % to about 10 weight %.
US08580153B2	Hydrogen production with reduced carbon dioxide generation and complete capture The present invention is a method of minimizing the emissions of carbon dioxide from a reformer furnace flue gas to the high pressure syngas exit water gas shift reaction unit. Including heating a first gas mixture by indirect heat exchange with one or more of an SMR furnace flue gas or an SMR furnace syngas, further heating the pre-reformed mixture in a primary reformer, thereby generating a second gas mixture comprising hydrogen, carbon monoxide, carbon dioxide, and a flue gas. Introducing the gas mixture into a standard H2 PSA unit, wherein the gas is separated into a hydrogen enriched stream and a PSA tail gas stream, and introducing PSA feed or tail gas stream into a carbon dioxide removal system, wherein the flue gas is separated into a residual flue gas stream and a carbon dioxide enriched stream.
US08580151B2	Flux addition as a filter conditioner Improvements in a gasification system and process for gasifying carbonaceous feedstock with improved energy efficiency. Improved methods and systems for more efficient removal of particulates from a raw synthesis gas while simultaneously providing a novel mechanism for fluxing agent addition to the gasification reactor. A conditioning agent, in the form of coarse fluxing agent particles, is added to the raw synthesis gas upstream from the particle filtration unit. The conditioning agent allows more rapid turnaround of the filtration unit following filter element replacement, extend filter life, facilitates the removal of filter cake from the particle filters, and combines with removed filter cake for recycling to the gasifier. Addition of fluxing agent via this route eliminates the need to premix fluxing agent with the carbonaceous feedstock, thereby maximizing the rate of feedstock addition to the gasification reactor.
US08580144B2	Blue phase liquid crystal nanocomposites and devices containing the same A composition including nanocomposites formed from blue phase liquid crystals that are stabilized with dopants and nanorods such as metallic nanorods and/or carbon nanotubes. Devices including the compositions are disclosed that provide increases temperature ranges as well as reduction in threshold voltage and turn on voltage, in addition to the inherent blue phase liquid crystal properties of sub-millisecond response time in the field induced Kerr effect.
US08580140B2	Cyclopropene complex compositions There is provided a composition comprising (a) one or more cyclopropene complex, and (b) 0-10% water by weight based on the weight of said composition, wherein the mole ratio of cyclopropene in said composition to molecular encapsulating agent in said composition is 0.92:1 or higher, or wherein the composition is in the form of a powder and, in a two-dimensional image of a representative sample of said powder, 20% or more of the area of the images of the particles of said cyclopropene complex, based on the area of all the images of all the particles of said cyclopropene complex in said image of said sample, is in the form of particles of said cyclopropene complex that have width dimension of 10 micrometers or larger. Also provided is a process for making a composition comprising cyclopropene complex.
US08580139B2	Dedusting compositions and methods for making and using same Compositions for reducing the formation of dust and methods for making and using same are provided. The composition can include an emulsion comprising one or more pitches, one or more fatty acids, one or more rosins, or any combination thereof. The composition can also include one or more film forming polymers, one or more oils, or a combination thereof.
US08580137B2	Trans-1,2-dichloroethylene with flash point elevated by 1-chloro-3,3,3-trifluoropropene A trans-1,2-dichloroethylene blend which comprises a combination of a major amount of trans-1,2-dichloroethylene and a minor amount of a hydrohaloolefin having an elevated flash point is disclosed The combination exhibits a flash point significantly higher than trans-1,2-dichloroethylene alone The preferred hydrohaloolefin is 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd) The subject blends find application as heat transfer agents, propellents and sprayable compositions, blowing agents, solvents and cleaning agents.
US08580135B2	Die and method of manufacturing same A mold of the present invention includes: a base 12 made of glass or plastic; an inorganic underlayer 14 provided on a surface of the base 12; a buffer layer 16 provided on the inorganic underlayer 14, the buffer layer 16 containing aluminum; an aluminum layer 18a provided on a surface of the buffer layer 16; and a porous alumina layer 20 provided on a surface of the aluminum layer 18a. The porous alumina layer 20 has a plurality of recessed portions 22 whose two-dimensional size viewed in a direction normal to the surface is not less than 10 nm and less than 500 nm. The mold of the present invention has excellent adhesion between the aluminum layer and the base.
US08580131B2	Plasma etching method It is an object of the present invention to provide a plasma etching method that can improve a selection ratio of a film to be etched to a film different from the film to be etched than that in the related art. The present invention provides a plasma etching method for selectively etching a film to be etched with respect to another film different from the film to be etched, the plasma etching method including etching, using gas that can generate a deposited film containing components same as components of the another film different from the film to be etched, the film on which generation of the deposited film is suppressed.
US08580129B2	Method for processing a surface A method for processing a surface involves depositing at least one class of enzymes (2) onto the surface (1); introducing at least a reactant (3) into an environment of the surface (1), and causing interaction between the enzymes (2) and the reactant (3), thereby to cause processing of a region of the surface (1), the processed region of the surface (1) being defined with respect to a region thereof that is proximate (4) to where the enzymes (3) have been deposited.
US08580126B2	Piezoelectric vibrating pieces comprising edge mesa steps, and methods for manufacturing same An exemplary method for a producing a piezoelectric vibrating piece having at least one mesa step includes forming a metal film on a main surface of a piezoelectric wafer. A through-groove is formed through the thickness of the wafer to form a plan profile of a desired piezoelectric substrate. A film of photoresist is formed on the surface of the metal film. A resist is applied, exposed, and formed into a resist pattern that defines a first mesa step along at least a portion of the plan profile. In regions not protected by the metal film, the piezoelectric substrate is etched to a defined depth to form a mesa step. The denuded edge surface of the metal film is edge-etched. A second mesa step, inboard of the first mesa step, can be formed by repeating the edge-etching and substrate-etching steps using the metal film as an etch protective film.
US08580123B2	Skimmer, barge and methods for recovering and transferring heavy oil or bitumen Skimmers, barges and related methods recover heavy oil or bitumen from contaminated water environments such as tailings ponds. The skimmer has an articulated mesh-like conveyor driven around a drum by a drive sprocket. A pusher mechanism discharges bitumen or heavy oil from cavities in the conveyor. In one embodiment, the skimmer includes an automatic depth control system. In other embodiments, knife-edged shear plates remove heavy oil or bitumen adhering to the conveyor and drum. A barge may incorporate multiple parallel skimmers. The barge may include a bitumen-transfer pump having an annular fluid-injection flange that generates an annulus of lubricating fluid inside a discharge hose. A method of skimming heavy oil or bitumen involves using a skimmer that automatically adjusts its elevation or depth based on a control signal generated by a depth sensor. Another method recovers and transfers bitumen by lubricating the discharge hose using the annular fluid-injection flange.
US08580122B2	Hybrid chemical/mechanical method and apparatus for inactivating and removing pharmaceuticals and other contaminants from water A hybrid chemical/mechanical water treatment plant and method employing rapid sulfur dioxide chemical disinfection and dewatering technology in conjunction with lime and oxidization/reduction agents to removal pharmaceuticals and personal care products from waters to meet operating constraints and environmental permitting restrictions and siting limitations for water treatment.
US08580117B2	System and method for replacing resist filter to reduce resist filter-induced wafer defects System and method for replacing a resist filter in such a manner as to reduce filter-induced wafer defects are described. In one embodiment, the system comprises a filtration system connected to a dispenser, the filtration system comprising a filter; and a switch connected to the filter for selectively connecting the filtration system to throughput one of a first chemical solution and a second chemical solution.
US08580116B2	Near-critical fluid extraction process A process for fractionating the constituents of a solution obtained by extracting plant or animal material with an aqueous-organic solvent where the aqueous-organic solvent is a mixture of water and a water-miscible organic solvent, generally including the steps of contacting the solution with a near-critical fluid to produce a raffinate phase containing high polarity constituents and water, and a near-critical fluid phase containing low to medium polarity constituents, separating the near-critical fluid phase from the raffinate phase, and recovering the low to medium polarity constituents from the near-critical fluid phase and the high polarity constituents from the raffinate phase.
US08580110B2	Blood treatment apparatus A proposed blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, the fluid pumps are configured to control the operation of the blood pumps via the blood treatment fluid. Moreover, a flow control device is configured to control a trans-membrane flow between the blood side and the a fluid side of the blood treatment unit. Hence, for instance ultrafiltration can be adjusted to a desired level in a very straightforward manner.
US08580106B2	Process for the treatment of oil residues coming from the oil industry The present invention relates to a process for the treatment of oil residues coming from the oil industry which comprises the recovery of the oil fraction of residues by extraction with solvents having a low environmental impact (ethyl acetate/toluene) and subsequent finishing for the downgrading of the residual material.
US08580104B2	Nanotube electrochemistry An electrode for electrochemical analysis is described, the electrode comprising: an insulating surface; a three-dimensional network of carbon nanotubes situated on the insulating surface; and an electrically conducting material in electrical contact with the carbon nanotubes; wherein the carbon nanotubes are oriented substantially parallel to the insulating surface. Also described is a method of manufacturing the electrode, and a method of electrochemically analysing a solution using electrodes of this type, and an associated assay device or kit.
US08580102B2	Method for the fast macropore etching in n-type silicon Method for the electrochemical etching of macropores in n-type silicon wafers, using illumination of the wafer reverse sides and using an aqueous electrolyte, characterized in that the electrolyte is an aqueous acetic acid solution with the composition of H2O:CH3COOH in the range between 2:1 and 7:3, with an addition of at least 9 percent by weight hydrofluoric acid.
US08580101B2	Outdoor-suitable antique copper color aluminum material and process A copper-substitute aluminum material made from a copper and cobalt anodizing process. The process includes the steps of: anodizing the aluminum material by submersing it in a basic sulfuric acid to build an anodic layer producing anodized aluminum material; combining copper and cobalt salts together in one bath; lowering the pH of the bath to between about 1.0 and about 3.0; coloring the anodized aluminum material electrolytically by submersing the anodized aluminum material in the bath of copper and cobalt salts; and applying an electrical current to the bath plating the copper and cobalt salts into the anodized aluminum material.
US08580098B1	Electrically enhanced cellulose filtration system Electrostatic filters, systems and methods having separate positively and negatively charged filter elements within electrically isolated filter tanks for electrostatically filtering particles from a fluid flow. Both positive charged connections biased to earth ground and negative charged connections biased to earth ground are made to the respective positive and negative charged filter elements, along with triboelectric induced charge accumulations from the fluid flow, for separating charged particles within the fluid flowing parallel through these oppositely charged filter elements. Variable resistors of a power supply connected to such filters, systems and methods provide for controlling and adjusting for any undesired voltage excesses and/or shortfalls within these filter tanks so that the fluid flowing exiting these filter tanks is unbiased to generate a filtered fluid having balanced electrostatic charges.
US08580094B2	Magnetron design for RF/DC physical vapor deposition Methods and apparatus to improve target life and deposition uniformity in PVD chambers are provided herein. In some embodiments, a magnetron assembly includes a shunt plate having a central axis, the shunt plate rotatable about the central axis, a first open loop magnetic pole arc coupled to the shunt plate at a first radius from the central axis, and a second open loop magnetic pole arc coupled the shunt plate at a first distance from the first open loop magnetic pole arc, wherein at least one of the first radius varies along the first open loop magnetic pole arc or the first distance varies along the second open loop magnetic pole arc. In some embodiments, a first polarity of the first open loop magnetic pole arc opposes a second polarity of the second open loop magnetic pole arc.
US08580090B2	Combinatorial electrochemical deposition Combinatorial electrochemical deposition is described, including dividing a wafer into a plurality of substrates for combinatorial processing, immersing the plurality of substrates at least partially into a plurality of cells, within one integrated tool, including electrolytes, the cells also including electrodes immersed in the electrolytes, depositing layers on the substrates by applying potentials across the substrates and the electrodes, and varying characteristics of the depositing to perform the combinatorial processing.
US08580089B2	System for the superposition of alternating current in electrolysis processes A system is submitted here that permits superimposing an alternating current in the process of electrolytic refining of metals based on the use of power semiconductors without requiring an external source and which minimizes the utilization of passive elements, achieving a high efficiency solution applicable to high power industrial processes. The invention consists of the division of the cells involved in the metals electrolysis process in two groups of cells (3a) and 3b, both comprising a similar number of anode-cathode pairings, and with both groups linked by a common point for electrical connection (6), and interconnected by means of a bidirectional power converter (7). Said power converter (7) is connected to the common point for electrical connection 6 of the groups of cells (3a, 3b) and to the other two connection points of each group of cells, so that its operation permits transferring power from one group to the other. This, the adequate operation of the bidirectional power converter permits superimposing an alternating current of variable frequency and breadth between the groups of cells, of an average value of zero, taking advantage of the storage (charge) and power supply (discharge) characteristics of the cells utilized in the electrolytic processing of metals.
US08580088B2	Method for producing transparent conductive film A method for producing a transparent conductive film including a transparent film substrate and a crystalline transparent conductive layer, including: a first depositing a first indium-based complex oxide having a first tetravalent metal element oxide on the transparent film substrate; and a second depositing indium oxide or a second indium-based complex oxide and lower than the tetravalent metal element oxide content of the indium-based complex oxide used in the first depositing by sputtering to form an amorphous transparent conductive layer, and crystallizing the amorphous transparent conductive layer. The method allows a reduction in crystallization time.
US08580087B2	Self-regenerating particulate trap systems for emissions and methods thereof A method and system for treating emissions includes charging particles in an exhaust stream, producing one or more radicals, and oxidizing at least a portion of the charged particles with at least a portion of the produced radicals. At least a portion of the charged particles in the exhaust stream are then attracted on at least one attraction surface which is one of oppositely charged from the charged particles and grounded. The attracted particles are oxidized with another portion of the one or more produced radicals to self regenerate the at least one attraction surface. Downstream from where the attracted particles are oxidized, at least a portion of one or more first compounds in the exhaust stream are converted to one or more second compounds downstream from the attracting. Additionally, at least a portion of any remaining charged particles are oxidized into one or more gases.
US08580085B2	Systems and methods for water distillation The invention is generally directed to solar distillation methods and systems for recovering potable water from non-potable water. In certain embodiments, a process for water distillation includes a cycled arrangement, alternating between a day cycle and a night cycle to enhance the yield of potable water. Additionally, in certain embodiments, the system includes a solar still having a design and orientation to maximize solar energy capture.
US08580084B2	Desalination method using a filter press A method of water desalination in a filter press may comprise: providing a chamber between two filter plates in the filter press, the chamber being lined by filter cloths; substantially filling the chamber with a plurality of beads; pumping water into the chamber filled with the beads; heating the water in the chamber; and collecting water vapor generated by the heating; wherein salts precipitate in the chamber during the heating. Furthermore, during the heating, the chamber may be vacuum pumped to facilitate removal of water vapor. The beads may be reused in the chambers of the filter press.
US08580082B2	Compositions of calcium carbonates/pigments for paper formulations, showing print through reduction The present invention relates to mixtures of two distinct porous, stable aggregates and rather coarse PCCs (precipitated) calcium carbonate pigments (such as a composition comprising a blend or mix of one of the two Grade B or Grade C PCCs, in combination with a second, specific S-PCC (S=scalenohedral type PCC) pigment in a ratio appropriately selected between 90/10 and 10/90 percent by dry weight, namely 80/20 and 20/80, with a coarser, third component, which may be a pigment and/or a filler such as natural calcium (ground) carbonate or (most preferably) a PCC (precipitated calcium carbonate), depending on the granulometry of the two fine PCCs the third, coarser component, may be omitted. The main criteria for selecting the said “coarser” pigment is that it should feature a granulometry which does no affect noticeably, when in admixture with the blend PCC Grade B (or PCC Grade C) with S-PCC the finest part of the granulometry data of the blend, and in particular that it should not contribute anything significant to the amount of particles <0.2 μm, preferably nothing <0.3 μm, more preferably nothing <0.5 μm and most preferably nothing <1 μm.
US08580081B2	Paper for smoking article having low ignition propensity properties The invention concerns a paper for smoking article, in particular for a cigarette, comprising areas treated with a coating formulation adapted to reduce the ignition propensity of said treated areas which comprises nanoparticles of cellulose having a median dimension (d50) equal to or less than five micrometers.
US08580078B2	Bevel etcher with vacuum chuck A bevel etcher incorporating a vacuum chuck used for cleaning the bevel edge and for reducing the bending curvature of a semiconductor substrate. The bevel etcher includes a vacuum chuck and a plasma generation unit which energizes process gas into a plasma state. The vacuum chuck includes a chuck body and a support ring. The top surface of the chuck body and inner periphery of the support ring form a vacuum region enclosed by the bottom surface of a substrate mounted on the support ring. A vacuum pump evacuates the vacuum region during operation. The vacuum chuck is operative to hold the substrate in place by the pressure difference between the top and bottom surfaces of the substrate. The pressure difference also generates a bending force to reduce the bending curvature of the substrate.
US08580077B2	Plasma processing apparatus for performing accurate end point detection A plasma processing apparatus for generating a plasma of a processing gas by applying a high frequency power to an electrode provided in a processing chamber and processing a substrate using the plasma is provided. The plasma processing apparatus includes an optical data detection unit, a data storage unit and a control unit. The optical data detection unit detects optical data when plasma processing the substrate. The data storage unit stores correlation data representing a correlation between type data corresponding to a plurality of types classified based on a type of a mask or a film to be processed disposed on the substrate and optical data to be detected by the optical data detection unit, and end point detection setting data sets, each of the setting data sets serving to detect a plasma processing end point and corresponding to one of the types.
US08580070B2	Method of applying an adhesive layer on thincut semiconductor chips of a semiconductor wafer The invention relates to a method for making a semiconductor. In one embodiment the method includes applying an adhesive layer to ground-thin or thinned semiconductor chips of a semiconductor wafer. In this embodiment, the adhesive layer composed of curable adhesive is introduced relatively early into a method for the thinning by grinding, separation and singulation of a semiconductor wafer to form thinned semiconductor chips, and is used further in a semiconductor device into which the thinned semiconductor chip is to be incorporated.
US08580068B2	Method for manufacturing rigid-flexible printed circuit board A method for manufacturing a rigid-flexible printed circuit boards includes following steps. First, a first rigid substrate is attached to a first adhesive layer. Second, a first opening through the combined first rigid substrate and the first adhesive layer is defined. Third, the first rigid substrate is laminated to a flexible substrate, the flexible substrate includes an exposed portion exposed via the first opening. Fourth, a second rigid substrate is attached to a second adhesive, a glass transition temperature of the second adhesive layer being lower than that of the first adhesive layer. Fifth, a second opening through the combined first rigid substrate and the first adhesive layer is defined. Sixth, the second rigid substrate is laminated to the flexible substrate in such a manner that the flexible substrate is sandwiched between the first and second adhesive layers, the exposed portion is exposed in the first and the second openings.
US08580065B2	Method for creating a diffractive optical effect on a target surface and a transfer foil of a diffractive optical element Method of creating a copied fine structure producing a diffractive optical effect onto the target surface, includes using a transfer foil manufactured from thermoplastic, on the surface of which is first created an original fine structure producing a diffractive optical effect; placing the transfer foil on the target surface with the original fine structure is in contact with the target surface; heating the transfer foil to a temperature close to the glass transition temperature of the material of the transfer foil; simultaneously during the heating or immediately after the heating lightly pressing the transfer foil against the target surface, whereby material from the transfer foil adheres to the target surface; and removing the transfer foil from the target surface, whereby the adhered material makes up a copied fine structure, which is a mirror image of the original fine structure of the transfer foil.
US08580060B2	Apparatus for preparing a pre-form An apparatus and a method for preparing a pre-form including at least one layer of fiber tows being at least partly fixed by a resin. The apparatus includes a work surface, a fiber tow distribution device, a fiber tow retention device, and a manipulation, device which is adapted to move the fiber tow distribution device relative to the fiber tow retention device. The apparatus is arranged so that free ends of the fiber tows can be delivered from the fiber tow distribution device to the fiber tow retention device, and the fiber tow retention device is adapted for retention of the free ends so that mutual movement of the fiber tow distribution device and the fiber tow retention device away from each other causes drawing of the fiber tows through distribution passage and distribution hereof onto the work surface.
US08580052B2	Method for the heat treatment of castings using an air quench and system for implementing the method The invention relates according to a first aspect to a method for the heat treatment of a batch of castings, in which an air quench is applied to the castings of the batch that are arranged in a single layer. The invention also extends to a system for the heat treatment of a batch of castings that includes a ventilation system in order to cause a flow of cooling air, characterized in that it includes means for placing the castings of the batch in a single layer and means for bringing the single layer of castings beneath the ventilation system so as to apply an air quench to the single layer comprising the castings of the batch.
US08580051B2	Method of processing steel and steel article A method of processing steel includes carburizing a martensitic stainless steel work piece to produce a carburized case by utilizing in combination, (i) a composition of the martensitic stainless steel work piece, (ii) a preselected carbon concentration in the carburized case, and (iii) a preselected grain size of the martensitic stainless steel work piece such that the carburized case predominately forms carbides of composition M6C, M2C, M23C6 or combinations thereof. The martensitic stainless steel work piece is then heated to substantially solution the metal carbides. The work piece is then quenched at a cooling rate that is sufficient to avoid substantial precipitation of any carbides during cool down to the martensite start temperature, then given a low temperature temper. In so doing, the carburized case hardened martensitic stainless steel will have balanced mechanical, tribological and corrosion resistance properties for high performance bearing and gear components.
US08580050B2	Carburized machine parts Disclosed is a carburized machine part which is free from the problem of decreased strength at edge-shaped parts due to excess introduction of carbon. The machine part is produced by processing a case hardening steel of the alloy composition consisting essentially of, by weight %, C: 0.1-0.3%, Si: 0.5-3.0%, Mn: 0.3-3.0%, P: up to 0.03%, S: up to 0.03%, Cu: 0.01-1.00%, Ni: 0.01-3.00%, Cr: 0.3-1.0%, Al: up to 0.2% and N: up to 0.05% and the balance of Fe and inevitable impurities, and satisfying the following condition: [Si %]+[Ni %]+Cu %]−[Cr %]>0.5 and carburizing by vacuum carburization.
US08580049B2	Modification of surfaces to increase the surface tension The invention concerns an analytical test element in which the sample liquid is transported from a sample application site to a determination site, where a detection site lies upstream of the sample application site in the transport direction. The analytical test element has at least one surface which is composed of at least one element that can be oxidized with water or an alloy that can be oxidized with water which has been treated by the action of boiling water or water vapor.
US08580047B1	Methods for using improved urea hydrochloride compositions A composition including HCl, urea, complex substituted keto-amine-hydrochloride, an alcohol, an ethoxylate, and a ketone is provided for performing hydraulic fracturing or oil or gas wells, solubilizing calcium carbonate, or lowering salt and bicarbonate levels in irrigation systems.
US08580035B2	Large aluminum nitride crystals with reduced defects and methods of making them Reducing the microvoid (MV) density in AlN ameliorates numerous problems related to cracking during crystal growth, etch pit generation during the polishing, reduction of the optical transparency in an AlN wafer, and, possibly, growth pit formation during epitaxial growth of AlN and/or AlGaN. This facilitates practical crystal production strategies and the formation of large, bulk AlN crystals with low defect densities—e.g., a dislocation density below 104 cm−2 and an inclusion density below 104 cm−3 and/or a MV density below 104 cm−3.
US08580034B2	Low-temperature dielectric formation for devices with strained germanium-containing channels A method of forming a semiconductor device includes providing a substrate in a vacuum processing tool, the substrate having a strained Ge-containing layer on the substrate and a Si layer on the strained Ge-containing layer, maintaining the substrate at a temperature less than 700° C., and generating a soft plasma in the vacuum processing tool. The Si layer is exposed to the soft plasma to form a Si-containing dielectric layer while minimizing oxidation and strain relaxation in the underlying strained Ge-containing layer. A semiconductor device containing a substrate, a strained Ge-containing layer on the substrate, and an Si-containing dielectric layer formed on the strained Ge-containing layer is provided. The semiconductor device can further contain a gate electrode layer on the Si-containing dielectric layer or a high-k layer on the Si-containing dielectric layer and a gate electrode layer on the high-k layer.
US08580033B2	Method for producing a single crystal of semiconductor material A single crystal of semiconductor material is produced by a method of melting semiconductor material granules by means of a first induction heating coil on a dish with a run-off tube consisting of the semiconductor material, forming a melt of molten granules which extends from the run-off tube in the form of a melt neck and a melt waist to a phase boundary, delivering heat to the melt by means of a second induction heating coil which has an opening through which the melt neck passes, crystallizing the melt at the phase boundary, and delivering a cooling gas to the run-off tube and to the melt neck in order to control the axial position of an interface between the run-off tube and the melt neck.
US08580028B2	Pigment additive for improving solar reflectance A pigment additive and resulting pigment are described that when incorporated in paints for example, significantly increases total solar reflectance. Also described are compositions utilizing the noted pigments, and related methods. The pigments are formed from iron oxide and/or chromium oxide and utilize as an additive, one or more phosphate compounds.
US08580020B2	Tank with containment chamber and gas scrubber The invention relates to a fluid storage tank having an interior volume and a floor and having an internal spill containment chamber comprising a vent gas scrubbing apparatus or scrubber. The chamber may be defined by a containment wall which completely separates the chamber from the tank interior volume. The containment wall may comprise an exterior portion which extends beyond the tank wall. The scrubber is disposed within the chamber and comprises a gas inlet passing through the containment wall into the tank interior volume, a gas outlet for venting scrubbed gases, and a gas scrubbing chemical storage and circulation system.
US08580016B2	Adjustable air flow bypass in a water vapor transfer assembly to reduce beginning of life water transfer variation A bypass unit for a water vapor transfer assembly includes a main body, a check valve, and an adjustable flow regulator. The main body has a conduit formed therethrough. The check valve is in communication with the conduit. The check valve normally militates against a flow of a bypass stream through the conduit and permits the flow of the bypass stream through the conduit above a threshold flow rate. The flow regulator is in communication with the conduit. The flow regulator permits an adjustment of the flow of the bypass stream to modify the water transfer rate of the water transfer assembly.
US08580015B2	Gas concentrator with improved water rejection capability A feed gas drying system is described for a PSA or VPSA oxygen concentrator. A membrane dryer is inserted into the feed gas path to the concentrator absorbent beds, such that the moisture in the feed gas is directed to a part of the dryer exposed to the concentrator exhaust, thus achieving efficient operation of the membrane dryer with no loss of concentrator feed gas.
US08580012B2	Solvent-resistant asymmetric hollow fiber gas separation membrane, and method for production thereof An asymmetric hollow fiber gas separation membrane obtained by subjecting an asymmetric hollow fiber polyimide membrane to a heat treatment having a maximum temperature of from 350 to 450° C., wherein the asymmetric hollow fiber polyimide membrane is formed with a polyimide essentially having a repeating unit represented by a general formula (1); is excellent in a solvent resistance and a thermal stability, and as well has such a mechanical strength that a tensile elongation at break is not less than 10% as a hollow fiber membrane. In the general formula (1), 20 to 80 mol % of A is a tetravalent unit based on a biphenyl structure represented by formula (2), 20 to 80 mol % of A is a tetravalent unit based on a diphenylhexafluoropropane structure represented by formula (3), and 0 to 30 mol % of A is a tetravalent unit based on a phenyl structure represented by formula (4); and in the general formula (1), 30 to 70 mol % of R is a divalent unit represented by formula (5) and/or formula (6), and 30 to 70 mol % of R is a divalent unit having one or two other aromatic rings than formula (5) or (6), wherein, R1 and R2 are a hydrogen atom or an organic group, and n is 0, 1 or 2, wherein, R1 and R2 are a hydrogen atom or an organic group, X is —CH2— or —CO—, and n is 0, 1 or 2.
US08580001B2	Method and apparatus for assembling gasification reactor injection devices A method of assembling a gasification reactor includes extending at least one reactant injection member into the gasification reactor. The method also includes extending at least one fluid injection conduit including a plurality of fluid injection passages defined therein into the gasification reactor. At least a portion of the at least one fluid injection conduit circumscribes at least a portion of the at least one reactant injection member.
US08580000B2	Indirect heat-drying apparatus, indirect heat-drying method of drying substance to be dried, and method and apparatus for producing solid fuel The present invention provides an indirect heat-drying apparatus that is resistant to adhesion of the substance to be dried on heating pipes and gives a product having a desired and stabilized liquid content.The present invention relates to an indirect heat-drying apparatus, comprising two indirect-heating rotary dryers, i.e., the first and second indirect-heating rotary dryers that are arranged in series so that the dried substance from the first indirect-heating rotary dryer is supplied to and dried in the second indirect-heating rotary dryer as the substance to be dried; and a carrier gas-supplying means of supplying the carrier gas co-currently in the first indirect-heating rotary dryer and counter-currently in the second indirect-heating rotary dryer, with respect to the flow direction from the substance to be dried.
US08579984B2	Shoulder joint repair A shoulder joint repair prosthesis (12, 14) comprises a support structure which comprises anchorage points (24) which are in the installed configuration positioned adjacent positions of the anatomical tendinous insertion points of the tendons related to the joint. A securing clamp (30) arrangement connects to the anchorage points with direct rigid connection devices (32), the securing clamp arrangement having a surface area larger than the direct connection devices, the securing clamp arrangement being arranged to clamp the tendons between the securing clamp arrangement and the underlying surface area and providing a fixed gap between clamp and underlying connecting areas to trap any attached bony fragments.
US08579982B2	Spinal implant having deployable bone engaging projections Instrumentation is disclosed for inserting an interbody spinal fusion implant for implantation at least in part within and across the generally restored height of a disc space between two adjacent vertebral bodies of a human spine. The implant has an external housing and a substantially hollow internal rotatable member having bone engaging projections that are deployable through the housing to penetrably engage the adjacent vertebral bodies.
US08579979B2	Expandable intervertebral spacers and methods of use An intervertebral spacer is inserted between vertebral members in a compact configuration and expanded post-insertion to contact the adjacent vertebral members. The intervertebral spacer comprises a first member and a second member movable with respect to the first member between retracted and extended positions.
US08579977B2	Spine surgery method and inserter A surgical inserter for use in inserting an implant into a vertebral space may include: (a) a handle; (b) a gripper having one end attached to the handle and a second end having a pair of arms; and (c) a grip activator having an opening that threadingly receives the gripper. The grip activator can be rotated in a first direction with respect to the gripper to cause the arms to move toward each other to grip the inserter and in a second direction with respect to the gripper to cause the arms to move away from each other to release the inserter. In one embodiment a compression force activator is used to deploy the implant and in another embodiment a tension force activator is used to deploy the implant.
US08579975B2	Double bundle ACL repair A system for single tunnel, double bundle anterior cruciate ligament reconstruction includes implant constructs and instruments. The implant constructs provide a combination of cortical fixation and bone tunnel aperture fixation. The implant constructs separate a graft into distinct bundles. The instruments are used to prepare shaped bone tunnels to receive the implant constructs and graft bundles. Methods for reconstructing the antero-medial and postero-lateral bundles of the anterior cruciate ligament may rely on single femoral and tibial tunnels and a single strand of graft.
US08579971B2	Inflatable intra ocular lens/lens retainer The invention provides for an inflatable intra ocular lens/lens retainer or a system of inflatable intra ocular lens/lens retainers, which are fitted into an aphakic eye, to substantially occupy the space previously held by the crystalline lens to retain and secure the position of delicate intra ocular structures of the eye. The inflatable lens/lens retainer may also be used suspend optical interfaces along the visual axis of the eye. The inflatable intra ocular lens/lens retainer may be pressed against residual elements of the lens capsule to re-establish accommodation. In the absence of a lens capsule, the inflatable intra ocular lens/lens retainer may be compressed directly by the ciliary muscle to alter the refractive state of the eye.
US08579968B1	Adjustable tricuspid ring Annuloplasty rings reduce or eliminate tricuspid regurgitation and/or tricuspid annulus dilation. An adjustable annuloplasty device includes a ring body having a first free end and a second free end. The ring body includes a shape memory material to provide a shape change to the adjustable annuloplasty device upon activation. The ring body includes a first segment including the first free end and following a curved path corresponding to an anterior leaflet region of a tricuspid annulus, a second segment following a curved path corresponding to a posterior leaflet region of the tricuspid annulus, and a third segment including the second free end and at least partially following a linear path corresponding to a portion of a septal leaflet region of the tricuspid annulus. Activation of the shape memory material changes a dimension of the adjustable annuloplasty device.
US08579967B2	Valve aptation assist device An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.
US08579963B2	Transcatheter prosthetic heart valve delivery device with stability tube and method A device for percutaneous delivery of a stented prosthetic heart valve. The device includes a sheath, a handle, and an outer stability tube. The sheath includes a distal capsule and a proximal shaft. The handle has a housing maintaining an actuator mechanism that is coupled to the shaft. The actuator mechanism is configured to selectively move the shaft, and thus the capsule, relative to the housing. The stability tube is coupled to the housing and is coaxially received over the shaft such that the shaft is slidable relative to the stability tube. In a delivery state, the capsule encompasses the prosthetic valve. In a deployed state, the capsule is withdrawn from the prosthetic valve. The shaft slides relative to the stability tube in transitioning from the loaded state to the deployed state. When used with an introducer device, the stability tube frictionally isolates the sheath.
US08579962B2	Methods and apparatus for performing valvuloplasty The present invention relates to apparatus and methods for performing valvuloplasty. In some embodiments, the apparatus includes an expandable braid valvuloplasty device. In some embodiments, the methods and apparatus may be used as an adjunct to percutaneous heart valve replacement. In some embodiments, the apparatus and methods may provide a medical practitioner with feedback, monitoring or measurement information, e.g., information relevant to percutaneous transcatheter heart valve replacement.
US08579960B2	Manufacture of fine-grained material for use in medical devices Medical devices are manufactured from fine grained materials, processed from of a variety of metals and alloys, such as stainless steel, cobalt-chromium and nickel-titanium alloys. A fine grained metal or alloy is formed from a specimen rapidly heated to its recrystallization temperature, and then subjected to high temperature, multi-axial deformation, for example, by heavy cross-forging or swaging. The deformed specimen may be cooled and reheated to a second recrystallization temperature. The metal or alloy in the specimen is then allowed to recrystallize, such that the grain size is controlled by quenching the specimen to room temperature. A desired medical device is then configured from the fine grained material. Decreasing the average grain size of a substrate material and increasing the number of grains across a thickness of a strut or similar component of the medical device increases the strength of the device and imparts other beneficial properties into the device.
US08579958B2	Everting stent and stent delivery system A stent delivery assembly is provided that includes a microcatheter, a delivery tube, a stent, and an elongate release member. The stent can have a first end that is (i) disposed within a delivery tube lumen and (ii) constrained by the delivery tube from radially expanding beyond a delivery tube lumen diameter. The stent can have a second end that is (i) disposed outside of a delivery tube distal end and (ii) substantially radially unconstrained by the delivery tube to expand beyond the delivery tube lumen diameter. The elongate release member can be moveable between first and second positions to engage or release the stent.
US08579957B2	Stent delivery device with embolic protection A delivery device adapted to insert and deploy a stent within a body lumen. The delivery device includes a guide member adapted to retain a dilation assembly and a stent within a lumen thereof until the stent is to be deployed into the body lumen. The delivery device is configured to enable simultaneous insertion of the guide member, dilation assembly, stent, and optional guidewire within a body lumen. Following deploying the stent, the delivery device can be removed, while providing the capability of optionally maintaining the guide member or the guidewire to function or act as an exchange wire for additional surgical devices.
US08579951B2	Fluorescent handpiece A handpiece can treat biological tissue using electromagnetic radiation, which can be substantially fluorescent light. The handpiece includes a source of electromagnetic radiation and a waveguide. The waveguide is adjacent the source, receives electromagnetic radiation from the source, and delivers the electromagnetic radiation to the biological tissue. The handpiece also includes a system for circulating a fluorescent substance through the waveguide. The fluorescent substance is capable of modulating at least one property of the electromagnetic radiation.
US08579947B2	Polyporous hollow bone screw Present invention depicts a poly-porous (micropore) hollow screws as diffusion chamber filled with core matrix for targeted delivery of growth factors and bone marrow stem cells. The screws comprise at least two parts: the distal part of the screw consists of the tip of the screw made of poly porous material and hollow inside proximally. It has threaded navel attached to the threaded nipple of the distal part of the proximal screw which has the screw head and is made of the solid material of the same kind. The screw head had hexagonal recess targeted for screw driver insertion. Assembly of screw created a chamber in the middle of the screw. The chamber is filled with core matrix consisting of gelatin nano-particles pre-impregnated with BMPs (BMP2/BMP7 for bone or BMP12 for tendon, ligament) and fibrin sealants or Chitosan dispersed with bone marrow stem cells and/or other growth factors. Bioactive protein core material is prepared during the surgery and filled the chamber of the screw by the surgeon. Fibrin sealants or Chitosan will polymerize to form a gel to hold the growth factors and stem cell in place. The screw can be used as the lag screw or other function to provide mechanical fixation in variety of condition. Once the screw implanted in the human body, the fibrin sealant or Chitosin/gelatin nano-particles are gradually degraded and slowly release growth factors and stem cells via micropores of screw to facilitate the bone healing and regeneration. The gelatin nanoparticles and fibril sealant/or Chitosan matrix also serve as the scaffold and platform for bone in-growth to the screw or alternatively, the stem cell inside of screw can regenerate new bone, providing the biological fixation. At the mean time as the bone regenerate and/or in growth, mechanical strength of the screw increased.
US08579942B2	Systems, methods and tools for spinal surgery A device and method for use in spinal surgery are provided.
US08579939B2	Silk / absorbable polyester hybrid medical devices and applications thereof Silk/absorbable polyester hybrid medical devices for tissue repair and regeneration are formed of degummed, naturally produced, multifilament silk yarn in combination with at least one absorbable polyester in the form of a surface coating, with or without an antimicrobial agent, for producing value-added braided silk sutures and multifilament yarn, as well as silk/absorbable polyester fiber composites, for producing tailored hybrid sutures, meshes, and scaffolds for tissue regeneration.
US08579933B2	Patent foramen ovale closure device A device for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The deployment device has a first tubular structure having proximal and distal ends. A second tubular structure is substantially coaxial to and slideably engaged within the first tubular structure. The second tubular structure has a first substantially linear shape when constrained within the first tubular structure, and a second curvilinear shape when telescopically extended from the distal end of the first tubular structure. A third tubular structure is substantially coaxial to and slideably engaged within the second tubular structure. The third tubular structure is configured to provide sufficient rigidity to push the mechanical closure device from the distal end of the second tubular structure, and provide sufficient flexibility to assume a curvilinear shape when deflected by the second tubular structure.
US08579929B2	Torsional ultrasound hand piece that eliminates chatter A torsional ultrasound surgical hand piece lessens or eliminates chatter from lens material by imparting a twisting, rotary motion to a tip of a phacoemulsification needle at a resonant frequency in excess of 32 kHz. The hand piece has a horn that is designed to operate at an elevated frequency while maintaining size constraints for hand-held ophthalmic instruments. Optionally, heat generation is reduced either through the use of a polyimide tubing situated between the needle and the infusion sleeve, through the use of thermal watch to prevent overheating at the incision, and/or through the use of a bypass hole in the needle that diverts flow under suction into the needle via the bypass hole instead of exiting through an irrigation opening in the infusion sleeve when a tip port is occluded by lens material.
US08579928B2	Outer sheath and blade arrangements for ultrasonic surgical instruments In various embodiments, a surgical instrument for operation in an aqueous environment is provided. In at least one embodiment, the surgical instrument may include a hollow sheath, a blade disposed at least partially within the hollow sheath and extending through an opening in the sheath, and at least one ultrasonic transducer operably coupled to the blade. The blade may include a polygonal cross-sectional shape and the tip may project away from the sheath's longitudinal axis. In another embodiment, the surgical instrument may include a blade with suction disposed therethrough and at least one ultrasonic transducer operably coupled to the blade. The blade may include a cutting edge that is positioned over a blade opening. Also, the cutting edge may project away from the blade's longitudinal axis.
US08579924B2	Implantable devices including a mesh and a pivotable film The present disclosure relates to implantable medical devices which include at least one mesh and at least one film pivotably attached to the mesh.
US08579918B2	Endoscopic surgical clip applier An apparatus for application of surgical clips to body tissue has a handle portion; a body extending distally from the handle portion; a plurality of surgical clips disposed within the body; and a jaw assembly mounted adjacent a distal end portion of the body. The jaw assembly includes first and second jaw portions movable between a spaced-apart and an approximated position. The apparatus also has a wedge plate longitudinally movable between the first and the second jaw portions, a clip pusher configured to individually distally advance a surgical clip to the jaw assembly while the jaw portions are in the spaced apart position; an actuator at least partially disposed within the body and longitudinally movable in response to actuation of the handle portion; and a jaw closure member positioned adjacent the first and second jaw portions to move the jaw portions to the approximated position.
US08579903B2	Devices and methods for stabilizing a spinal region Apparatuses and methods deliver implants through a posterior aspect of a vertebral body such as a pedicle and place the implant or perform a procedure into the anterior aspect of the vertebral body. A representative apparatus includes an outer cannula, an advancer tube and a drill assembly. It is envisioned that at least one of the outer cannula, the advancer tube or the drill assembly can be viewed in vivo using for example, a CT scan or fluoroscope. Also included is an apparatus for forming an arcuate channel in bone material. The apparatus includes an advancer tube and a drill assembly.
US08579900B2	Minimally invasive skeletal fixation device A minimally invasive skeletal fixation device includes two curved tubes and two positioning members. The two curved tubes are attached to each other and are in communication with each other. The positioning members are coupled to the curved tubes. The device is applicable to surgical operations for treating bone fractures and offers the advantages of small incision size, simple structure, easy operation, improved performance of surgical operation, and flexible adjustment of installation sites of Kirschner pins.
US08579899B2	Bone fixation system A bone fixation system has a first fixation device. The first fixation device has a first longitudinally extending bone insertion blade having an orienting portion, and a first plate extending transversely from the first bone insertion blade and positionable along a surface of a bone. The bone fixation system further has a second fixation device. The second fixation device has second longitudinally extending bone insertion blade orientatively interactive with the orienting portion, and a second plate extending transversely from the second bone insertion blade and positionable along the surface of the bone adjacent the first plate. When assembled, the second bone insertion blade has an orientation that is based on an orientation of the orienting portion.
US08579898B2	Adjustable-angle radius plate A bone plate for a fracture between an epiphysis and a diaphysis has an outer part unitarily formed with a fan-shaped outer end having a plurality of outer holes and an inner end extending from the outer end. A bar-shaped inner part has an outer end juxtaposed with the inner end of the outer part and formed inward of its outer end with a plurality of inner holes. A pivot is provided between the inner end of the outer part and the outer end of the inner part. Formations juxtaposed with the pivot on the inner end of the outer part and on the outer end of the inner part are lockable together in each of a plurality of angularly offset fixed positions of the inner and outer parts. When the formations are pressed together the inner and outer parts are locked angularly relative to each other.
US08579896B2	Method and system for invasive skin treatment A system and method for simultaneously heating a plurality of discrete skin volumes to a coagulation temperature. The system comprises an applicator containing an electrode having a plurality of spaced apart protruding conducting elements configured to contact the skin surface at a plurality of discrete locations. A controller applies a voltage to the electrode so as to simultaneously heat a plurality of skin volumes to a coagulation temperature when the applicator is applied to the skin surface.
US08579894B2	Electrosurgical system An electrosurgical tool can be used to fuse tissue. The electrosurgical tool can include a jaw assembly, an elongate shaft, and a handle assembly. Actuation of the handle assembly can actuate the jaw assembly. The elongate shaft can be rotatable without disrupting electrical connection to the jaw assembly. The electrosurgical tool can include a cutting blade to separate fused tissue. The electrosurgical tool can also include a jaw assembly configuration or an exterior cutting electrode to improve surgical access with the tool.
US08579893B2	Medical system and method of use A tissue evacuation device may be designed to provide a high-energy fluid (e.g., a heated vapor) to targeted tissue for breaking down the targeted tissue, such as the nucleus of an intervertebral disc. An inner tube positioned within an outer tube, having a nozzle coupled to distal ends of the tubes, having a heating element positioned between the inner and outer tubes, delivers a heated vapor through a port to the nozzle to break down tissue. After the nucleus or other targeted tissue is broken down, the tissue evacuation device may also remove some or all of the broken down tissue.
US08579889B2	Linear ablation devices and methods of use Described herein are various methods and devices for delivering cryoablative therapy. Various ablative patterns can be produced by the devices, including, linear ablation patterns. One exemplary device includes a cryoablation chamber and a volume displacement chamber. In use, the volume displacement chamber can be expanded to support the cryoablation chamber.
US08579887B2	Axially reciprocating microsurgical instrument with radially compressed actuator handle A microsurgical instrument has a pair of operative surgical surfaces that are moved relative to each other in shearing or grasping procedures performed by the instrument. The instrument has a handle containing an elongate center rod with a ring mounted for reciprocating movement on the rod. A tube is secured to the ring and a shaft extends through the tube and is secured to the rod. The handle also includes a plurality of resilient arms that extend along the length of the rod and engage against a sliding surface of the ring on the rod. The plurality of actuator arms are alternatively manually compressed radially inwardly by the surgeon's hand and released by the surgeon's hand to allow the arms to flex radially inwardly and outwardly. The inward and outward movement of the plurality of arms reciprocates the ring on the handle rod and causes the tube and shaft to move axially relative to each other.
US08579886B2	Accordion style cable stand-off A cable stand-off for use with an electrosurgical system includes an accordion body portion having a plurality of panels, and a plurality of hinges. Each panel has at least one hole formed therethrough. The holes of the plurality of panels are axially aligned with one another. The plurality of hinges couples adjacent panels to one another. In one embodiment, the hinges couple adjacent panels in a tip-to-tail fashion. The accordion body portion may be made of a flexible material. Each panels may further include at least one slot extending from a hole to an edge of the panel.
US08579883B2	Body-insertable apparatus and medical agent discharge method A body-insertable apparatus according to an aspect of the present invention is introduced into a subject to inject medical agent stored in a casing into a desired part in the subject. The body-insertable apparatus includes a fixing unit which fixes the casing to the desired part; and a projecting unit which projects, from the casing, an injection needle for injecting the medical agent. The fixing unit and the projecting unit are driven by a driving source.
US08579879B2	Closed-loop glucose control startup Disclosed are methods, systems, etc. for closed-loop glucose control startup. In certain example embodiments, a request for entry of an automatic mode of operation of a glucose monitoring and insulin delivery system for a patient may be detected. An entry of the automatic mode of operation may be controlled based, at least in part, on a detected rate of change of blood glucose concentration of the patient. In certain other example embodiments, initiation of a continual phase of an automatic mode of operation may be controlled based, at least in part, on a time since a most recent manual delivery of a bolus, on a detected rate of change of blood glucose concentration, on a targeted fixed set point, a combination thereof, and so forth.
US08579878B2	Hanger label for a liquid bag and method for attaching a label to a liquid-filled bag A special label is adapted for labeling of infusion bags containing a liquid. The bag is labeled only in a small partial area, which does not contain any liquid. For safe labeling capable of being automated, the label consists of a special film composite, which makes it possible to form a flap with special hinge properties. By virtue of the special fastening options, accidental detachment of the label from the infusion bag is prevented.
US08579871B2	Disposable, sterile fluid transfer device The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
US08579869B2	Needle mounting system and a method for mounting a needle assembly A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first portion that defines a passageway substantially parallel to a longitudinal axis of the needle mount and a second portion substantially perpendicular to the axis. The needle hub and mount provide a method wherein a needle assembly may be mounted on an injection device without completely rotating the needle hub relative to the needle mount.
US08579867B2	Medication delivery device A medication delivery device comprising a housing, a medication receptacle, a piston rod which is moveable distally, and a drive device for rotating the piston rod in a first rotational direction. The piston rod comprises two threaded sections, a first threaded section for threaded engagement with a reset element and a second threaded section for threaded engagement with the drive device. In an operational state, the reset element is prevented from rotating and the piston rod prevented from moving proximally. In a resetting state, the reset element is allowed to rotate, such that the delivery device is resettable by rotating the piston rod and the reset element in a second rotational direction and moving the piston rod proximally.
US08579866B2	Systems and methods for administering medication The syringe systems disclosed herein provide in part devices for allowing patients with comprised joint strength to more easily administer medicine. Certain exemplary syringe embodiments include a handle forming a handgrip, a syringe barrel that magnifies the dosage marks located on an inner barrel, and a tip cap slidably engageable with the syringe barrel for shielding a needle.
US08579864B2	Anchor systems and methods Some embodiments of a medical device anchor system include an anchor device that receives a medical instrument (such as a catheter or the like) and secures the instrument in place relative to a skin penetration point. In some circumstances, the anchor device may allow the anchor device to be used after medical instrument is already in place without the need for a second penetration point for the anchor device.
US08579863B2	Catheter patch The present invention relates to a patch, which can be used to secure catheters, wound drainage devices, and/or drug delivery devices, when said catheter and related devices are inserted into the body. The invention also can deliver antimicrobial substances to the site of insertion of a catheter and related devices into a body as well as other medicinal factors, such as wound and tissue healing factors that may be desired to be delivered to the site of insertion.
US08579858B2	Catheter pump for circulatory support A catheter pump intended to be inserted in the circulatory system of a mammal, for example for assisting the heart. The catheter pump comprises: a hollow catheter (2); a drive cable (1) arranged in a lumen (6) of the catheter (2); a sheath (3) surrounding the hollow catheter (2); a drive shaft (5) connected to a distal end of the drive cable (1) to be rotated by the drive cable; a propeller (4) arranged at the drive shaft; and a cage (11) surrounding the propeller. The propeller and the cage are moveable from a folded position, wherein the catheter pump has a small cross-sectional dimension of about 3.3 mm to an unfolded position wherein the unfolded cage surrounds the unfolded propeller and the size of the cage is about 19.5 mm. The drive shaft comprises a distal bearing (24) and a proximal bearing (25). A purge system is arranged for passing fluid in a lumen (7) along the hollow catheter to the proximal bearing, for purging and lubrication of the proximal bearing. The fluid is returned outside the drive wire. A portion of the fluid is passed into channels (22) for passing fluid from the proximal bearing to the distal bearing, for purging and lubrication of the distal bearing.
US08579857B2	Manual irrigation pump for intraprocedural irrigation A disposable manual irrigation pump system comprises a manual foot pump operatively coupled to a fluid reservoir and an associated intraprocedural device. The pump system is configured to provide a substantially continuous fluid supply at a desired flow rate from the fluid reservoir to the associated intraprocedural device along a first direction without backflow of fluid along a direction opposite the first direction.
US08579856B2	Unit dose drug delivery platform The delivery systems of the present disclosure are configurable to administer either single-dose or multiple-doses of one or more substances to a user, for example to the eye, nose, mouth, ear or rectum of the user. The precise and repeatable dosing features of the presently disclosed delivery systems overcome many of the disadvantages associated with known methods for dispensing substances to, for example, the eye of a user. The delivery systems administer precise doses of a substance to a precise location from unit dosage forms that may be single-dose or multiple-dose unit dosage forms, which may be externally or internally pierced.
US08579853B2	Infusion devices and methods Medical devices having restrictive access, and methods thereof are provided.
US08579851B2	Surgical system having means for isolating vacuum pump The present invention provides a surgical system 10 for aspiration of a biological material comprising a source of irrigation fluid 20, a collection cassette 30, a pump 40 for creating a vacuum in the collection cassette 30, a handpiece 50 applied to a surgical area for infusing irrigation fluid and for aspirating a biological material, conduits 60 and 62 connecting the handpiece to each of the source of irrigation fluid and the collection cassette and means 70 for isolating the pump from the handpiece to prevent creation of vacuum within the conduit 62 and the collection cassette 30 after receiving a stop signal.
US08579849B2	Pyloric valve devices and methods A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a disc-shaped inlet and a helical flange. The helical flange may be disposed in a contracted position defining a contracted length and a contracted diameter and an extended position defining an extended length and an extended diameter, wherein the extended length is longer than the contracted length and the extended diameter is smaller than the contracted diameter. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its contracted and extended positions. Insertion and removal systems are also provided for use with the pyloric valve.
US08579845B2	Wound heat exchanger A capillary tube bundle sub-assembly for use in an extracorporeal heat exchanger includes a continuous capillary tubing wound about a core to define a plurality of capillary layers each including a plurality of capillary segments. The capillary segments each define opposing terminal ends adjacent opposing ends of the core. The capillary segments of each layer are circumferentially aligned relative to an axis of the core, with each successive layer being radially outward of an immediately preceding layer. The capillary segments are non-parallel with the axis, spiraling partially about the axis in extension between the opposing terminal ends. Each capillary segment forms less than one complete revolution (i.e., winds less than 360°). The segments within each layer are substantially parallel with one another; however, an orientation of the segments differs from layer-to-layer such as by pitch or angle.
US08579843B2	Knee joint bandage A knee joint bandage made of elastic textile material having a profiled insert encompassing the kneecap in a recess, the insert being covered by an overlay fastened to the textile material. Within the profile insert is a flexible, non-expandable tensioning member for connecting the regions of the kneecap poles on the fibula side in an arc around the kneecap wherein the distance between these regions increases during bending of the knee joint, the distance of the arc from the connecting line of the knee poles is decreased, and the tensioning member presses on the adjacent side of the kneecap, displacing the same medially and centering it. The bandage is provided with a flexible tensioning band, which partially covers the kneecap in its peripheral area relative to the tensioning member, the tensioning band substantially extends in the direction between the kneecap poles such that it counteracts a lifting of the kneecap.
US08579841B2	Blood clot prevention device An adjustable pressure cuff device is provided for the arm or leg of a user for stimulating blood flow and preventing blood clots. The pressure cuff contains a number of bladders which wrap in the direction of the cuff and which are arranged in succession down the arm or leg of a user. An air compressor is connected to the bladders via a multiplicity of tubes, each of which contain a valve. A control module runs the air compressor and sequentially opens the valves to provide air pressure to the bladders in succession along the arm or leg of a user. Further, between the bladders and the valves, additional tubes containing valves are provided to equalize pressure between bladders before exhausting the air from a previously pressurized bladder to save power and allow for increased patterns of bladder pressure. The pressure levels and bladder dwell times may be adjusted by the user or based on predetermined settings. Optionally, the device provides electrical stimulation, pulsations, heating, and cooling.
US08579839B2	Methods for recovery from motor control via stimulation to a substituted site to an affected area Methods, devices and systems for recovering motor control of an area in the body of a patient affected by a neurological disorder. A device vibrotactilely stimulates a substitute site for the affected area thereby recovering the motor control of the affected area. The stimulation provided by the device is volitionally controlled by the patient.
US08579837B1	Devices and methods for promoting female sexual wellness Devices, systems, and methods for promoting female sexual wellness and function. The devices, systems, and methods encourage clitoral engorgement using suction over the clitoris combined with vibratory stimulation.
US08579836B2	Treatment apparatus and operation system A treatment apparatus of the present invention includes a treatment section that performs treatment of a treatment target region of a treatment subject, a detection section that detects cavitations that are generated in accordance with a treatment of the treatment section, and a control section that controls a generation state of cavitations at the treatment target region by controlling a physico-chemical parameter of the treatment section based on a detection result at the detection section.
US08579833B2	Thrombosis and osteoporosis prophylaxis Use of a device to reduce risk of thrombosis and osteoporosis, which uses a pressure transducer to measure the forefoot force generated by a person with their forefoot, and generates a signal so that the person can recognize whether their forefoot force has reached a minimum value.
US08579831B2	Method and apparatus for penetrating tissue A skin penetrating system is provided with a drive force generator and a disposable housing member. A plurality of penetrating members are positioned in the disposable housing member. Each penetrating member is coupled to the drive force generator. A plurality of analyte detecting members are each associated with a penetrating member and are positioned in the disposable housing member. Each analyte detecting member is positioned in a sample chamber with a volume of less than 1 μL, The sample chambers have openings for transport of a body fluid into the sample chamber. Each analyte detecting member is configured to determine a concentration of an analyte in a body fluid using a sample of less than 1 μL of a body fluid disposed in the sample chamber. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
US08579830B2	Neuropathy diagnostic device A neuropathy diagnostic device includes a body having a neutral temperature surface disposed on an exterior of the body, a variable temperature surface disposed on the exterior of the body, and a vibrating surface having a variable vibration amplitude. The vibrating surface extends outwardly from the body. A touch sensor extends outwardly from the body. A processor is disposed within the body. The processor is adapted to set a temperature of the neutral temperature surface, vary a temperature of the variable temperature surface, and vary the vibration amplitude of the vibrating surface.
US08579826B2	Arteriosclerosis degree judgment device capable of judging arteriosclerosis degree precisely A cuff of a pulse wave meter equipped with an arteriosclerosis degree judgment device has air bags for compressing a living body having a double structure along an artery including an avascularization air bag and a pulse-wave measuring air bag. Provided at outer circumferential sides of these air bags are a curler for integrally pressing these air bags against an upper arm, and an air bag for pressing the curler from the outer circumferential side. A member for suppressing vibrations is provided between a curler-compressing air bag and the pulse-wave measuring air bag, and suppresses propagation of vibrations from the curler-compressing air bag to the pulse-wave measuring air bag. The pulse wave meter measures a pulse wave based on changes in internal pressure in the pulse-wave measuring air bag while the avascularization air bag provides avascularization at the peripheral side.
US08579825B2	Electrically conductive guide wire The present invention relates to a measuring device, insertable into a living body. The device includes an elongated flexible member in the form of a thick-walled hollow tube with a proximal end and a distal end. The tube defines a central lumen with an inner wall. The lumen may contain a core and an insulating material provided between the core and the inner wall. The core may be made of an electrically conductive material and may be of essentially constant diameter over its entire length. Alternatively, the lumen may contain at least two electrical leads. An electrical sensor is attached to the distal end of the elongated flexible member and is electrically connected to the core.
US08579815B2	Device, method, and graphical user interface for searching, filtering and displaying event-aligned information sets related to diabetes A device, method, and graphical user interface for displaying diabetes related information sets aligned by the occurrence of a particular event are disclosed. After receiving a request for an event-aligned display of diabetes related information based on an event, a search for a plurality of tagged occurrences of the event and retrieval of an information set for each of the plurality of tagged occurrences is provided. Each information set may include diabetes related information chronologically related to the tagged occurrence. The retrieved information sets is displayed on a display, wherein the retrieved information sets are shown on the display aligned by their tagged occurrences such that all diabetes related information is positioned relative the event based on its chronological relationship with the event.
US08579807B2	Absorbing fluids in a surgical access device The present invention generally provides methods and devices for removing fluid from a surgical instrument. Surgical access devices and seal systems are generally provided having one or more valves or seal assemblies to create a closed system between the outside environment and the environment in which the surgical access device is being inserted. In one embodiment, a seal assembly is provided and can include a seal having an opening configured to receive a surgical instrument therethrough and a fluid remover in the form of an absorbent element, a scraper element, a wicking element, or any combination thereof can be associated with the seal and configured to remove fluid from the opening and/or a surgical instrument.
US08579806B2	Force-determining retraction device and associated method A retraction device adapted to retract tissue is provided, comprising at least one pair of opposed retraction members, with each retraction member being capable of operably engaging the tissue to be retracted. A drive mechanism is operably engaged with at least one of each pair of retraction members for separating one of each pair of retraction members from the other to retract the tissue. A measuring device is operably engaged with at least one of the drive mechanism and one of each pair of retraction members, for determining and/or controlling a magnitude and/or rate of a force and/or strain imparted to the tissue by the drive mechanism via the retraction members as the tissue is being retracted. Associated devices and methods are also provided.
US08579802B2	Flexible endoscope with modifiable stiffness An apparatus includes a flexible elongate member that defines a lumen and is configured to be inserted within a body passageway of a patient. The flexible elongate member includes a proximal portion, a distal portion, and a medial portion disposed between the proximal portion and the distal portion. The distal portion is movable between a substantially linear configuration and a curved configuration. A stiffening member is coupled to the flexible elongate member. The stiffening member is movable to a selected location along a length of the flexible elongate member to provide modified flexibility to the selected location of the flexible elongate member. The stiffening member may include a first portion and a second portion, the first portion having a first stiffness and the second portion having a second stiffness different than the first stiffness. The stiffening member may be disposed within a lumen or at an exterior portion of the flexible elongate member.
US08579800B2	Systematic chromoendoscopy and chromocolonoscopy as a novel systematic method to examine organs with endoscopic techniques An endoscopic screening system uses an apparatus has an endoscope with an upper/lower wheel and a right/left wheel for controlling bending of an endoscope tip within an organ being imaged; an intelligent mouthpiece adapted to precisely measure inclination of the endoscope using marks in degrees in both the novel mouth piece and in the new shaft; an endoscope shaft having both cross and longitudinal marks along a longitudinal length for digitalization of output to precisely obtain the length of insertion from a reference point to a tip of the endoscope; and an angulation device for measuring rotation of the upper/lower and right/left wheels. Every portion/part/side located within an organ is already assigned an alphanumeric code as part of the new nomenclature. The endoscopic screening system allows for imaging sequentially of an entire interior surface of a portion of the patient's gastrointestinal tract and image reconstruction of the surface with overlapping redundant pictures without image gaps.
US08579798B2	External cardiac stress reduction method An external heart wall stress reduction apparatus is provided to create a heart wall shape change. The device is generally disposed to the exterior of a heart chamber to reshape the chamber into a lower stress configuration.
US08579797B2	Methods and apparatus for securing and tensioning a urethral sling Improved methods and apparatus to secure a urethral sling to pubic bone in a sub-urethral location to support the urethra and alleviate incontinence are disclosed. The urethral sling is preferably formed of a flexible sheet material extending between opposed first and second sling ends and bounded by opposed first and second sling sides. The urethral sling is selectively tensioned in a central portion intermediate the first and second sling ends and/or in one or both of end portions bracketing the central portion. In one embodiment, pre-positioned plicating lines in the central portion are selectively drawn and tied to slacken the central portion and tension the end portions. In further embodiments, bone anchor lines passed through locations displaced from the sling ends are drawn and fixed to tension the central portion between the displaced locations and slacken the end portions.
US08579794B2	Agitator to stimulate the central nervous system A tactile and audible sensation can be provided to a patient using a coiled or scrolled film in response to a received control signal. The tactile and audible sensation can be configured to stimulate the patient's central nervous system to sufficiently interrupt and undesirable sleep behavior of the patient, but avoid significantly changing a sleep state of the patient.
US08579781B2	Recloseable flexible bag The flexible packaging (10) comprises a body (22) which has, at the outer side, at least one main face (26) which is formed at least partially by a flexible sheet (12). It comprises a reclosing strip (43) which is separate from the flexible sheet (12) and an adhesive (44) which can be reactivated by means of pressure and which is interposed between the outer surface of the flexible sheet (12) and the reclosing strip (43), the adhesive strength of the adhesive (44) to the surface of the reclosing strip (43) being greater than the adhesive strength of the adhesive (44) to the outer surface of the packaging sheet (12), the reclosing strip (43) and the packaging sheet (12) having identical structural features.
US08579778B2	Machine and method for forming reinforced polygonal containers from blanks A machine for forming a container from a blank of sheet material is provided. The blank includes a reinforcing panel assembly for forming a reinforcing corner assembly. The machine includes a hopper station for storing the blank in a substantially flat configuration and a forming station for forming the blank into the container. The forming station includes an initial forming station that rotates a first portion of the reinforcing panel assembly with respect to a second portion of the reinforcing panel assembly, and a secondary forming station having male and female forming members with shapes corresponding to an interior shape and an exterior shape of the reinforcing corner assembly, respectively. The male and the female forming members are configured to form the reinforcing corner assembly by compressing together the first and second portions of the reinforcing panel assembly.
US08579777B2	Method and device for producing box of corrugated board sheet Disclosed is a method for producing a board box by performing a box-making process of a corrugated board sheet which is formed to have dimensions of a plurality of board boxes wherein the yield of the board sheet and the production efficiency are enhanced and a countermeasure can be taken against paper powder. A method for making a box of a corrugated board sheet by performing a box-making process of a board sheet (S) which is formed to have dimensions of a plurality of board boxes and the cutting the board sheet (S) into dimensions of one board box comprises a step (I) for cutting the board sheet (S) into dimensions of one board box by a cut line (k) in the direction intersecting the conveyance direction (a) along a box making line (PL) after a ruling and grooving step (C) and before a pasting and folding step (E), and a speed increase step (J) for spacing the board sheets (S1) and (S2) thus cut by a set dimension following to the cutting step (I) by increasing the speed of the board sheets (S1) and (S2) while conveying toward a subsequent step.
US08579770B2	Pull cord starter dock A gyroscopic exerciser starting dock has a starter dock housing and a starter dock axle mounted within the starter dock housing. A driving wheel is mounted to the starter dock axle. A retractable pull cord grip sleeve device is mounted to the starter dock axle and has a pull handle attached to a pull cord. The pull handle is for pulling the pull cord, and the pull cord is attached to the handle at a pull cord first end. A spool receives around it a pull cord and a pull cord is attached to the spool at a pull cord second end. The spool member receives and stores the pull cord in a coil around the spool.
US08579769B2	Step-cycling apparatus An apparatus comprising, a paddle lever, a hinge joint, the hinge joint pivotally attached to the paddle lever, a hydraulic piston, the hydraulic piston pivotally attached to the paddle lever, a crankshaft, a piston bar, the piston bar pivotally attached to the paddle lever on a first end and to the crankshaft on a second end, a chain assembly, the chain assembly interlocked to the crankshaft, and a wheel, the wheel attached to the chain assembly by a rear axle, wherein a force pushes down the paddle lever hinged on the pivot joint, the force is transmitted to both the hydraulic piston and the crankshaft at the same time therefore rotating the wheel. A method of transportation comprising, using human force to simultaneously move a crankshaft and a hydraulic piston, whereby a wheel is rotated.
US08579763B2	Shift-by-wire gearshift control apparatus In a shift-by-wire gearshift control apparatus, even if a switching anomaly in which switching between forward and reverse gears is not possible has occurred, transmission of driving power to the output shaft 10 can be interrupted as quickly as possible. In the case of the occurrence of a switching anomaly in which switching from a forward gear stage to a reverse gear stage, or vice versa, is not possible, as a path for draining engaging hydraulic pressure supplied to a frictional engagement element (C1 to C4, B1, B2) involved in establishing the current gear stage, the hydraulic control circuit 4 secures an anomaly drain path (91 or 92) that is shorter than a normal drain path (81, 82 or 83) secured by the hydraulic control circuit 4 during normal switching.
US08579761B2	Gearshift control method for a motor vehicle A gearshift control method for a motor vehicle whose drive train comprises a turbo-charged combustion engine, a startup clutch and a shift clutch and an automatic stepped transmission, in which drive engine torque deficiencies, that occur during the build-up of load at the end of a tractive upshift, are avoided without assisting the engine with an additional device or increasing the charge pressure. The method provides that the engine accelerates at the earliest, after the disengagement of the load gear, and at the latest, at the start of the load build-up after the engagement of the target gear up to the boost threshold speed or an engine speed which is slightly above the boost threshold speed, and is loaded, during the load build-up, with a largely constant engine speed beyond the intake torque of the engine to nearly the full load torque, before slipping of the friction clutch ends.
US08579757B2	Roller frictional transmission unit A roller frictional transmission unit includes: a first roller; a second roller; an input shaft connected with a driving system of main driving wheels, and connected with one of the first roller and the second roller; an output shaft connected with a driving system of auxiliary driving wheels, and connected with the other of the first roller and the second roller; a thrust bearing arranged to position an input shaft side rotation section including the one of the first roller and the second roller and the input shaft, or an output shaft side rotation section including the other of the first roller and the second roller and the output shaft, with respect to a unit housing in an axial direction; and a low rigidity structure disposed in a thrust transmission path to the thrust bearing, and arranged to buffer a thrust.
US08579749B1	Transmission device A transmission device 100 with an input 101 and output planetary set 102 connected by two co-axial shafts 110 and 111 such that the combination of a gear and speed ratio is possible without interrupting the torque path between the engine or prime mover and the wheel using an electromechanical control apparatus comprising of two motor generators 117 and 118 that also provides electric torque to complement the mechanical torque. The current powerflow is increased by the planetary configuration and continuous power regeneration during torque and inertia phases. Where the carrier 108 can engage the engine to the transmission 100 and where the hybrid torque is transmitted by engaging the vehicle load to the transmission.
US08579748B2	In-vehicle power transmission device and power transmission system for vehicle An in-vehicle power transmission apparatus is equipped with a motor-generator working as an engine to drive a vehicle and a power split device made up of a plurality of power split rotors. A first one of the rotors is coupled to a driven wheel of the vehicle, while a second one of the rotors is coupled to an accessory such as an air compressor of an air conditioner. The speed of the second rotor is controllable independently of that of the driven wheel. This eases restrictions on the supply of power produced by the generator-motor to the accessory. Alternatively, the rotors are so linked that when the speed of the first rotor is not zero (0), the speed of the second rotor has one of zero (0) and a value other than zero (0), thus ensuring the stability in supplying the power to drive the vehicle to the accessory.
US08579742B2	Game ball having optimally positioned grooves and/or ridges A football having first and second ends and including a bladder, a cover and a lacing. The cover is disposed over the bladder and defines channels. The cover has an outer surface and includes a plurality of ridges. The height of the ridge is greater than or equal to 0.7 mm and less than or equal to 10 mm. The football includes an upper central region positioned between first and second upper end regions, and a lower central region positioned between first and second lower end regions. The lacing is coupled to the upper central region. The ridges extend over the upper central region, the first and second upper end regions, and the first and second lower end. The lower central region is formed without ridges. The lacing has a first length and the lower central region has a second length that is generally equal to the first length.
US08579740B2	Bouncing ball amusement device having reduced transparency A ball amusement device including an outer shell of transparent or semi-transparent plastic or elastomer or plastomer having good bounce characteristics, and at least one liquid within the shell. The outer shell may be configured to reduce the transparency to light through the ball.
US08579739B2	Arrow shaft having front/rear two-stage spine structure Provided is an arrow shaft having a front and rear two stage spine structure and including a front end to which an arrowhead is coupled and a rear end to which a nock is coupled, wherein the arrow shaft has a hollow tubular shape and is divided and defined into a front part and a rear part in a longitudinal direction thereof such that spine strengths of the arrow shaft are different between the front part including a center of gravity of the arrow shaft and the rear part to which the nock is coupled; wherein the front and rear parts of the arrow shaft are formed by an arrow shaft shaping sheet constituted of three layers; wherein an uppermost layer of the arrow shaft shaping sheet includes a front sheet and a rear sheet respectively formed of a carbon fabric sheet each having different elastic strengths.
US08579738B2	Racket with replaceable grip sleeve A racket includes a main body, a replaceable grip sleeve, a nut and a bolt. The main body has a frame, a handle having at least one hole, and a bridge connected between the frame and the handle. The replaceable grip sleeve is sleeved onto the handle and provided with at least one through hole aimed at the hole of the handle. The bolt is inserted through the through hole of the replaceable grip sleeve and screwingly engaged with the nut disposed in the hole of the handle. The user can replace the replaceable grip sleeve of a predetermined size to meet his/her need.
US08579737B2	Goal apparatus Goal apparatus comprising a frame, a first pliable goalpost member, a second pliable goalpost member and a pliable crossbar member. The frame presents net connection points and is configured to support each of the pliable goal members in tension between two net connection points such that the goal apparatus presents a substantially rectangular goal mouth. A frame for use in the goal apparatus. A net for use in the goal apparatus comprising first, second and third edges, and a first pliable goalpost member, a second pliable goalpost member and a pliable crossbar member extending along the first, second and third edge respectively.
US08579736B2	Moveable soccer goal safety system In a soccer goal consisting of a framework supporting a net arranged to trap a soccer ball passing through the mouth of the frame upon scoring a goal, a safety device for preventing the shifting of the framework from a playing field position or from tipping over from misuse or player impact consisting of a weighted roller attachable or attached to the rear of the framework and resting on the playing field opposite the mouth which roller is either permanently weighted by construction of a heavy material or is constructed of a sealed shell fillable with a liquid such as water or a flowable particulate substance such as sand. In addition to providing the necessary weight to stabilize the goal, the rollers facilitate the repositioning of the goal for storage or to clear a playing field for other purposes.
US08579735B2	Method and apparatus of teaching serving in tennis Disclosed is a method and a device for practicing a tennis serve, learning how to perform a tennis serve, and for teaching a student how to perform a tennis serve. The method includes placing an indicator band on the server's thumb joint, placing a positioning indicator on the throat of the server's racquet, standing at the baseline in a serving position, bringing the racquet to the tossing hand and physically touching the positioning band on the thumb with the indicator band on the racquet, dropping both hands together, one hand holding the ball and one hand holding the racquet, then extending the throwing hand skyward and releasing the ball with the palm of the hand up, and bringing the racquet around and striking the ball at the apogee of its arc.
US08579732B1	Jumping game assembly A jumping game assembly includes a mat having a plurality of panels. Each of the panels forms a target area configured for being jumped upon by a user. The panels are arranged into rows and columns defining adjacently positioned interior edges of the panels and outer edges of the panels. The outer edges correspond to an outer perimeter of the mat. A plurality of interior strips is coupled to and extends between the adjacently positioned interior edges of the panels. An upper border is coupled to and extends around the outer edges of the panels. A disc is configured for throwing onto the mat to distinguish one of the panels on which the disc lands as a jumping target for a game played by jumping on the mat in accordance with a set of rules.
US08579730B2	Low lift golf ball A golf ball having a plurality of dimples formed on its outer surface, the outer surface of the golf ball being divided into plural areas comprising at least two groups of areas, a first group of areas containing a plurality of first dimples and a second group of areas containing a plurality of second dimples, the areas being arranged to form a spherical polyhedron shape, the first and second groups of areas and dimple shapes and dimensions being configured such that the golf ball is spherically symmetrical as defined by the United States Golf Association (USGA) Symmetry Rules and such that the first and second groups of areas produce different aerodynamic effects, and the first dimples being of different dimensions from the second dimples.
US08579727B1	Fairway wood type golf club head A fairway wood type golf club head and method for forming is disclosed herein. The golf club head preferably has a cast body, a compression molded crown, and weight pads. The weight pads can be manipulated to create different mass property configurations for the golf club head using the same body and crown.
US08579725B1	Golf club head with vertical center of gravity adjustment Golf club heads include at least one weight port situated to retain weights and positioned above an approximate club face geometric center with the club in a standard address position. One, two, or more weight ports can be located above the club face center in a club crown or other portion of a club body. Club head vertical center of gravity can be selected to compensate dynamic loft associated with locating the club head center of gravity well behind the club face. Three-dimensional adjustment of club head center of gravity is possible.
US08579724B2	Golf club head with adjustable weighting A titanium bodied driver that utilizes a lightweight receiving back cap, which is designed to be non-removable from the club head but can be loosened to allow its interior to be accessed to reposition one or more movable weights into alternative receiving locations, is disclosed herein. The back cap may also be designed to be completely removable from the driver body to gain access to the one or more weights that can be re-positioned in alternative receiving areas within the back cap's interior.
US08579719B2	Golf training aid A golf swing training aid in the form of a modified golf tee including an indicator for indicating the target line from the tee to the target and a second indicator for indicating the preferred swing path of a golf club for moving the ball toward the target line and in the direction of the target.
US08579716B1	Golf putter with adjustable head A golf putter including a handle from which exends a shaft having a lower extension connected to a hosel mounted on an adjustable putter head having a putting face, upper and lower surfaces, opposite side portions, an alignment groove extending along a central longitudinal axis of the upper surface toward the putting face, a first pair of alignment members extending parallel to and on opposite sides of the groove, and a second pair of alignment members extending parallel to and adjacent the putting face, and wherein at least one alignment projection extends from the hosel above the first and second pairs of alignment members.
US08579715B2	Amusement slide elements and systems Leisure and amusement slide elements and systems are disclosed. In one embodiment, a waterslide includes a bowl having a curved sidewall, two or more rider entrances for enabling riders to slide into the bowl and to circuit at least a portion of the bowl, and a receptacle for forming a pool of water to receive a rider exiting the bowl. A nozzle is provided for directing a jet of water to bias a rider towards an edge of the pool. Another slide apparatus includes a bowl having upper and lower ends and first and second entrances distinct from one another and spaced apart from the bowl lower end. The first and second entrances are configured to bias all users of the first and second entrances to travel about at least a portion of the bowl in a common direction, whether clockwise or counter-clockwise.
US08579713B2	Torsional damper assembly A torsional damper assembly for transmitting torque between a prime mover of a powertrain and an input of a transmission is provided. The torsional damper assembly includes an input mass, an output mass, a damping element, a bypass clutch, and a bypass clutch release lever. The damping element is interposed between the input mass and the output mass, and it is operable to translate torque between the masses and to dampen oscillation generated by the prime mover. The bypass clutch is configured to couple the input and output masses together for common rotation when engaged. The bypass clutch release lever is pivotally rotatable with respect to the output mass, and it includes a biasing portion and a weighted end. When rotated, the biasing portion is operable to bias the bypass clutch away from the input mass to disengage the bypass clutch.
US08579709B2	Multi-player bingo game with progressive jackpots Methods and gaming units for conducting a wagering game and an associated progressive jackpot in a gaming network having a plurality of operatively coupled gaming units are described. A progressive jackpot award amount may be determined in part based on the amount of the player's wager for the occurrence of the wagering game in relation to a maximum wager amount that may be made on one of the gaming units in the gaming network. The progressive jackpot pool may include a main pool and a reserve pool. Portions of players' wagers being added to the progressive jackpot pool may be apportioned between the main pool and the reserve pool based on calculation performed at the gaming network, with the apportionment being at least partially determined by the amount in the main pool.
US08579707B2	Angling joystick and gaming device having same An exemplary embodiment of an angling joystick includes a body, an orientation indicating unit, an imitation fishing reel and a transceiver unit. The orientation indicating unit is attached to the body and is configured for indicating an orientation of the body. The imitation fishing reel is attached to the body and includes a lever and a force-adjusting device. The lever is rotatably connected to the force-adjusting device. The transceiver unit is electrically connected to the force-adjusting device and is configured for receiving control signals. The force-adjusting device is configured for adjusting a rotating resistance to the lever according to the control signals.
US08579703B2	Cashless computerized video game system and method A system and method for operating one or more games for a plurality of players including identifying at least two players participating in a selected one of the games at the expiration of a predetermined time period, and establishing a wager pool corresponding to a total of wager amounts from each of the identified players. The wager pool is reduced by a takeout amount. One or more random numbers are generated, and one or more winners of the selected game are determined based on the one or more random numbers. Funds are distributed from the wager pool to the determined one or more winners of the selected game.
US08579702B2	Gaming system having tools for categorizing wagers and metering performance of wagering games and supplemental features A method of operating a wagering game comprises receiving one or more configuration inputs to create at least one wagering game configuration. The at least one wagering game configuration comprises at least one base game and at least one portal game. The at least one base game is operable in response to receipt of a primary wager, the primary wager being within a range of allowable wagers. The range includes minimum and maximum allowable wagers. The at least one portal game having a set of eligibility criteria. The method further comprises creating a plurality of wager categories based upon the set of eligibility criteria and a size of the primary wager, activating participation in the at least one portal game if the set of eligibility criteria is satisfied, and metering the entire primary wager to a single wager category.
US08579699B2	Gaming system, gaming device and method for providing an outcome enhancing feature An embodiment of a gaming device includes a game having at least three choices, wherein each of the choices either trumps or is trumped by one of the other choices, and a processor programmed to determine if an outcome enhancing condition is satisfied, enable a player to elect to enhance an outcome if an outcome enhancing condition is satisfied, enable the player to select one of said choices, select one of said choices, determine an outcome based on a comparison of the player's choice with the processor's choice, provide a win outcome if the player elected to enhance an outcome and the comparison of the player's choice with the processor's choice results in a draw determination, provide a draw outcome if the player elected to enhance an outcome and the comparison of the player's choice with the processor's choice results in a lose determination.
US08579693B2	System and method for implementing an additional game to players of a lottery game A system and method for providing an additional or end-of-game drawing to players of a lottery game is provided. In one embodiment, unique validation codes provided on lottery tickets can be encrypted using an algorithm and used to create a record of such encrypted codes. A player then participates in the lottery and subsequently submits the validation code from the ticket to a lottery provider. The lottery provider applies the algorithm to the submitted validation code to create another encryption code for comparison with the record of encrypted codes. In the event a match is found, the player is entered into a second-chance or end of game drawing. Upon entry, the player is no longer required to maintain possession of the ticket for subsequent validation.
US08579686B2	Gaming event prediction system and method The system and method for operating an online gaming event prediction game involves obtaining answers from a plurality of players at a plurality of game playing consoles to a plurality of predictive questions relating to possible outcomes of a plurality of elements of one or more scheduled competitive events, assigning point values to the answers, determining cumulative point scores for each of the plurality of players, and awarding prizes to the plurality of players, via an online game server and a communication network.
US08579681B2	Rotary dressing tool containing brazed diamond layer A disc-shaped, rotary dressing tool has a rigid core and an abrasive rim around at least one surface of the periphery of the rigid core. The rigid core and the abrasive rim are oriented in a direction orthogonal to the axis of rotation of the tool. In an embodiment, the abrasive rim comprises an abrasive component bonded to the rigid core by means of an active braze. The abrasive component can be diamond grains arranged in a single layer or diamond film inserts. In a particular embodiment, the abrasive component can comprise a plurality of abrasive inserts mechanically fastened to the rigid core. In another embodiment, the abrasive rim can comprise strips of an abrasive component with each strip being filled into slots machined into and through the perimeter of the core.
US08579680B2	Centerless grinding machine A centerless grinding machine includes a frame with an upper base and includes a driven regulating wheel and a driven grinding wheel mounted to the frame. At least one of the wheels is mounted to the upper base and hangs downwardly from the upper base. At least one of the wheels is indexable laterally along an X direction. The wheels are for supporting and grinding a work piece placed between the grinding wheel and the regulating wheel. Preferably the upper base is spaced from and above the at least one wheel and the regulating wheel and the grinding wheel are operably mounted to the upper base such that the wheels hang downwardly from the upper base.
US08579677B2	Abrasive impregnated brush An abrasive brush includes a securing element and a plurality of abrasive filaments secured to the securing element to form a brush. Each abrasive filament includes a matrix of thermoplastic polymer and a plurality of alumina abrasive particles interspersed throughout at least a portion of the matrix. The abrasive particles comprising a polycrystalline alpha alumina having a fine crystalline microstructure characterized by an alpha alumina average domain size not greater than 500 nm. The alumina abrasive particles further include a pinning agent comprising a dispersed phase in the polycrystalline alpha alumina.
US08579675B2	Methods of using optical metrology for feed back and feed forward process control A method includes polishing a substrate on a first platen using a first set of parameters, obtaining a plurality of measured spectra from at least two zones, comparing the plurality of measured spectra with a reference spectrum to evaluate the thickness of each of the at least two zones of the substrate, comparing a thickness of a first zone with a thickness of a second zone, determining whether the thickness of the first zone falls within a predetermined range of the thickness of the second zone, and if the thickness does not fall within the predetermined range, at least one of a) adjusting at least one parameter of the first set and polishing a second substrate on the first platen using the adjusted parameters, or b) adjusting at least one parameter of a second set and polishing the substrate on a second platen using the adjusted parameters.
US08579671B2	Custom remote controlled vehicle kit A method, apparatus, and computer software to provide a kit which allows an operator to construct a variety of vehicles such as cars, boats, hovercraft, airplanes, etc. The operator can use software to select characteristics of the vehicles, and then print out sheets of paper or other thin material that can then be folded into a vehicle. Motors can be inserted into each vehicle in order to propel the vehicle. The kit can also comprise special tools which allow for forming the paper or other material into particular three dimensional shapes. The kit can also comprise a remote control transmitter and receiver so that the vehicles can be controlled remotely.
US08579669B2	Gear housing for an aquatic vessel, breakaway safety system for an aquatic vessel and aquatic vessel A gear housing for an aquatic vessel is adapted to be attached at an attachment site to an underside of a hull of the aquatic vessel. The gear housing includes at least one weakened region adapted to yield when the gear housing is rotated at the attachment site following an impact. A breakaway safety system includes such a gear housing, and a fracturable member for attaching the gear housing to the hull at the attachment site, wherein the weakened region is adapted to yield such that the fracturable member fractures. An aquatic vessel includes such a gear housing or such a breakaway safety system.
US08579668B2	Vessel propulsion apparatus A vessel propulsion apparatus includes a nozzle, a deflector, and a forward bucket (hereinafter referred to as “F bucket”). In a state in which the F bucket is in a closed position and the deflector is positioned at a left side, water jetted obliquely rearward to the left from the deflector is guided by the F bucket in a left guiding direction that is tilted further to the left than a direction of jetting of water from the deflector. In a state in which the F bucket is in the closed position and the deflector is positioned at a right side, water jetted obliquely rearward to the right from the deflector is guided by the F bucket in a right guiding direction that is tilted further to the right than the direction of jetting of water from the deflector.
US08579667B2	Electric connection structure An electric connection structure includes a plurality of strip-like first terminals and a plurality of second terminals welded to ends in a longitudinal direction of the first terminals. The first terminals are arranged in parallel with intervals therebetween. The first terminals are arranged so that at least a part thereof faces each other. The first terminals are arranged to be offset in the longitudinal direction alternately so that the ends of the first terminals in the longitudinal direction project. The second terminals are welded to the ends in the projected sides in the longitudinal direction in the first terminal.
US08579664B1	Ethernet connector with integrated USB Manufacturers or vendors may desire to occlude connection ports on a device that are used to upload software onto the device. An implementation discloses inserting two pins into a first cavity of an Ethernet connector and two additional pins into a second cavity of the Ethernet connector. The pins may be bent over the connector and soldered to a printed circuit board. The four pins may correspond to the at least four pins required by a USB specification. Also disclosed is an adapter or cable that may connected.
US08579661B2	High speed modular jack A modular jack (100) is adapted to be mounted onto a horizontal mother printed circuit board (PCB). The modular jack comprises a housing (200) defining an upper row of ports and a lower row of ports vertically stacked in columns, a number of vertical PCBs (46, 47) extending along a front-to-rear direction and being aligned laterally, a number of shield modules (500, 54) each having a vertical shield plate (50, 548) and an insulating portion (48 and 49, 55) at least partially encapsulating the vertical shield plate. Each of the vertical PCB electrically connecting with a set of mating contacts extending into one of the upper row of ports and the lower row of ports. The vertical PCBs and the shield modules are stacked side by side in an alternating manner.
US08579658B2	Coaxial cable connectors with washers for preventing separation of mated connectors Coaxial cable connectors including washers are described herein. A coaxial cable connector configured in accordance with an embodiment of the present technology includes a conductive insert, a coupling nut, and a washer. The coupling nut can include a first end portion, a second end portion, and an inner surface defining a bore for receiving a corresponding coaxial cable connector. The conductive insert can include an annular flange at least partially surrounded by the bore. The washer can be positioned between the second end portion of the coupling nut and the annular flange, and can be configured to press against at least one of the annular flange and the second end portion of the coupling nut to restrict rotation between the coaxial cable connectors.
US08579652B2	Fastening device for an electric cable A fastening device for an electric cable is provided with an outer casing (15) in which on one side a nut (12) can be screwed, by means of which at least one clamping ring (20) pressing against the outer insulation of the cable (11) can be arranged adjustably. The clamping ring (20) is provided with a number of segments (22) connected to one another and respectively moveable approximately radially, which each have on their inner surface at least one projection (24). The respective projection (24) is formed such that the latter is pressed in when the nut (12) is screwed into the outer insulation of the cable (11). A consistently long service life and also inexpensive production of this type of fastening device is thus made possible.
US08579649B2	Flexible wiring member with positioning holes mounted on another member with positioning bosses A flexible concentrated wiring connector includes a flexible concentrated wiring member, a first member, a second member. The flexible concentrated wiring member is clamped between the second member and the first member. A second clearance is set to be greater than a first clearance. The first clearance is defined as a difference between an internal dimension and an external dimension in the width direction of the flexible concentrated wiring member in a state that a first positioning boss of the first member is inserted into the center of a first positioning hole of the flexible concentrated wiring member. The second clearance is defined as a difference between an internal dimension and an external dimension in the width direction in a state that a second positioning boss is inserted into the center of a second positioning hole.
US08579647B2	High speed electrical contact assembly A contact assembly that comprises an outer body and an insert assembly receivable in the outer body. The insert assembly includes a housing and a conductive bather received in the housing. The conductive barrier defines first and second receiving areas in the housing. At least a first contact member is receivable in the first receiving area and at least a second contact member is receivable in the second receiving area. Each of the first and second contact members is adapted to accept a conductor.
US08579645B2	Connector mechanism for connecting a board card A connector mechanism for connecting a board card is disclosed. The connector mechanism includes a circuit board, and a connector installed on the circuit board. An end of the board card is for inserting into the connector. The connector mechanism further includes a socket installed on the circuit board and located on a side of the connector, a rotating component pivoted to the socket, and at least one connecting component slidably installed on the rotating component and coupled to the circuit board for contacting with the other end of the board card so as to electrically connect to the board card as the end of the board card is inserted into the connector and the rotating component rotates to a connection position.
US08579644B2	Anti-vibration connector coupling with disengagement feature A connector coupling that comprises a connector body, a first collar that receives the connector body, and second collar that surrounds the first collar. A movable ratchet ring is supported by the connector body and includes at least one locking member. The movable ratchet ring is axially movable with respect to the first collar between engaged and disengaged positions. A stationary ratchet ring is coupled to the first collar and includes at least one locking member. When the movable ratchet ring is in the engaged position, the locking members of the rings are engaged, and rotating the second collar from the first position to the second position with respect to the first collar moves the movable ratchet ring to the disengaged position away from the stationary ratchet ring such that the locking members are disengaged, thereby allowing rotation of the first collar with respect to the connector body.
US08579642B2	Device for producing and removing an electrical plug connection One plug connecting element is mounted on its device part in a side wall of a recess. The other plug connecting element is mounted on a swivel holder. When the one device part is inserted into the other device part, the swivel initially pushes the other plug out of the way of the one device part as it is being inserted. Further insertion causes the swivel holder to move the other plug into the recess in a position to mate with the one plug.
US08579641B1	Multi-orientation plug An electrical adapter system includes a housing that includes a receiving portion, the housing including first electrical contacts and second electrical contacts disposed at the receiving portion. The electrical adapter system includes a plug that includes a body, electrical prongs extending from a surface of the body, and electrical contacts coupled to the electrical prongs. The body of the plug is receivable by the receiving portion in at least two orientations such that in each of the at least two orientations, the electrical prongs extend outward from the housing, and one or more of the electrical contacts of the plug engage at least one of the first electrical contacts or at least one of the second electrical contacts.
US08579640B2	Electrical connector device An electrical connection device comprises an electrical connector and a carriage. The electrical connector comprises a housing, a cage, and a plurality of terminals. The housing has a body, the terminals are provided in the body. The cage encloses the housing, and defines, together with the housing, an insertion slot, and an opening of the insertion slot corresponds to a front end of the body. The carriage can be slidably positioned in the insertion slot. The housing comprises at least a clamping slot provided close to the front end in the body, the carriage has a clamping block mating with the clamping slot, the carriage is releasably held to the electrical connector by clampingly connecting the clamping slot to the clamping block.
US08579639B2	Systems and methods for coupling input/output devices An input/output (I/O) device for an automation control system includes a base portion configured to communicatively connect the I/O device with at least one other I/O device, an I/O module physically and communicatively connected to the base portion and comprising I/O communication circuitry, a terminal block physically and communicatively connected to the base portion, and an ejection device configured to eject the I/O module or the terminal block from the base portion by pushing the I/O module or the terminal block out of engagement with the base portion when activated.
US08579637B2	Electrical connecting system An electrical connecting system is described for contacting an electronic module with multiple printed conductors of a flexible printed circuit. The printed conductors are enclosed between a lower and an upper cover film, and the electronic module has at least one circuit board hich is embedded in a plastic housing. According to the invention, the electronic module has at least one contact spring. A first end section of the contact spring is connected in an electrically conductive manner to the circuit board via a connecting point, and a second end section of the contact spring has two legs which extend in a U shape, between which a printed conductor is situated. An electrical contact which is less susceptible to failure results on both sides between the contact spring and the printed conductor. Also described is an electrical connecting system in which the printed conductor is electrically contacted on one side, and instead of at least one one-piece contact spring, in each case a connecting piece and a spring clip are present. The electrical connecting systems allow an electrically reliable connection to be established which is also sufficiently capable of withstanding mechanical load, by simply inserting the printed circuits into the contact springs, or between the connecting pieces and the spring clips in the electronic modules.
US08579631B2	Clean real smoke fire simulator A simulator for use in firefighting training exercises comprising a fire compartment having a flame; a means for generating a flame; a means for generating smoke into the fire compartment; a control room for controlling the means for generating a flame and the means for generating smoke; a means for expelling the smoke from the fire compartment; a means for oxidizing the smoke; and a stack for releasing the oxidized smoke from the oxidizing means.
US08579629B2	Dental handpiece A dental handpiece is disclosed which has a head housing, a gear shaft having a gear part with gear teeth and a shaft part extending from the gear part, and a dust control seal sealingly fit on the circumferential surface of the shaft part of the gear shaft. The dust control seal is an annular member, and has a seal body, a first lip projecting radially inwardly from the seal body, and a second lip projecting radially inwardly from the seal body above and spaced apart from the first lip, with a space defined between a contact area between the first lip and the shaft part, and a contact area between the second lip and the shaft part.
US08579627B2	Method and a device for controlling the feed of a combustible gas to a burner apparatus A method is provided for controlling the feed of a combustible gas by a valve device placed in a feed pipe which has a gas inlet section and a gas outlet section. The device includes a valve seat in the pipe associated with a membrane-operated plug and a device for returning the plug to a position in which the valve seat is shut off. The method includes the steps of creating a pressure difference in a section of the pipe downstream of the plug with respect to the direction of flow, by a constriction in the pipe having a predetermined cross section, the pressure difference being defined by a first pressure upstream of the constriction and a second pressure downstream of the constriction; collecting the signal formed by the second pressure downstream of the constriction and making the second pressure act on the side of the membrane opposite that on which the first pressure acts; and generating a regulatable load on the membrane of the membrane operating system.
US08579626B2	Nozzle for a machine for manufacturing containers Pressurized gas injecting device (14) for a machine (1) for blow molding or stretch blow molding a container from a blank (2) of plastic material. The device has a nozzle (15) movable between an upper position separated from a mold (9) intended to receive the blank (2) and a lower position pressed against the mold (9) while covering a neck (3) of the blank (2); an insert (36) mounted movably with respect to the nozzle (15), the insert (36) having a lower end face (45) capable of being pressed against a lip (4) of the blank (2); and a return device (44) applying force on the insert (36) toward a lower position in which the insert (36) is at the end-of-travel stop with respect to the nozzle (15), and in which the lower end face (45) of the insert (36) extends beyond the nozzle (15).
US08579624B2	Systems and methods for making multi-wall corrugated pipe A system is disclosed for manufacturing multi-wall corrugated polymer pipe. The system includes an extruder configured to co-extrude concentric annular tubes; a corrugator configured to form the concentric annular tubes into a dual-wall pipe having a smooth wall and a corrugated wall; a cross-head die configured to extrude an outer wall of pipe onto the corrugated wall of the dual-wall pipe; a vacuum punch configured to penetrate the outer wall of pipe and draw a vacuum between the corrugated wall and the outer wall, such that the outer wall of pipe deforms inward toward the corrugated wall of pipe between bell and spigot portions of the corrugated wall; and a cutter configured to cut the pipe into sections where the vacuum punch deformed the outer wall between the bell and spigot portions of the corrugated wall. A method of manufacturing multi-wall corrugated polymer pipe is also disclosed.
US08579623B2	Extruder stabilizer assembly A stabilizer assembly for use in an extruder having a screw rotating in a barrel is provided. The assembly comprises a plurality of rods that are secured to an interior of the barrel at one end. Each of the rods has an end that extends radially inwardly toward the center of the barrel. On the discharge end of the screw, there is a bearing member that is in contact with each of the opposite ends of the rods. The rods support the discharge end of the screw and stabilize its rotation in the barrel.
US08579622B2	Blowing machine A blowing machine used to produce containers of correctly temperatured preforms in blowing stations including correctly temperatured blow molds, having functional get-up components such as at least electric servomotors assigned to at least the blowing stations to control and/or monitor secondary functions of functional get-up components during production. In order to bring at least some of said functional get-up components for secondary functions to the correct temperature, an electrically operated, controllable liquid temperature control system is supplied by at least one temperature control device and is integrated into the blowing machine and guided through the functional get-up components.
US08579614B2	Scroll compressor with three discharge valves, and discharge pressure tap to back pressure chamber A scroll compressor has a housing enclosing a compressor pump unit which includes an orbiting scroll member and a non-orbiting scroll member. Each of the orbiting and non-orbiting scroll members include a base and a generally spiral wrap extending from the base. The wraps interfit to define compression chambers, with a central-most discharge pressure chamber, and circumferentially spaced intermediate pressure chambers being defined. The base of the non-orbiting scroll includes ports associated with the intermediate pressure chambers. At least one port is associated with the discharge pressure chamber. Valves are associated with each of the ports. A discharge plenum is defined downstream of the ports and valves within the housing. A back pressure chamber is defined behind the base of one of the orbiting and non-orbiting scroll members, and taps a refrigerant from the discharge pressure chamber.
US08579612B2	Peristaltic pump tubing with stopper and cooperative roller assembly housing having no moving parts A peristaltic pump system includes elastomeric pump tubing and a roller pump. The pump tubing has a pumping segment and an inlet segment. The inlet segment has an inlet segment outer diameter. The pumping segment has a pumping segment outer diameter less than the inlet segment outer diameter. The roller pump has a roller assembly and a roller assembly housing. The roller assembly is disposed within the roller assembly housing and engaged with the pumping segment within the roller assembly housing. The roller assembly housing has an inlet gap formed through the roller assembly housing. The inlet gap defines an inlet gap inner diameter smaller than the pumping segment outer diameter. The inlet gap is adapted to frictionally receive the inlet segment for aligning the pump tubing with a roller assembly and mitigate longitudinal movement of the pump tubing into the roller assembly housing.
US08579607B2	Rotary blood pump with opposing spindle magnets, bore and drive windings Various “contactless” bearing mechanisms including hydrodynamic and magnetic bearings are provided for a rotary pump as alternatives to mechanical contact bearings. In one embodiment, a pump apparatus includes a pump housing defining a pumping chamber. The housing has a spindle extending into the pumping chamber. A spindle magnet assembly includes first and second magnets disposed within the spindle. The first and second magnets are arranged proximate each other with their respective magnetic vectors opposing each other. The lack of mechanical contact bearings enables longer life pump operation and less damage to working fluids such as blood.
US08579605B2	DC-AC frequency converter type mucus suction device The present invention provides a DC-AC frequency converter type mucus suction device having an electromagnetic pump, the pressure and the flow generated in which could be changed to satisfy the requirement of the mucus suction device. The mucus suction device of the present invention comprises an electromagnetic pump, a suction device and a frequency converter circuit, wherein the frequency converter circuit at least comprises an oscillator circuit, a bistable circuit, and a push-pull circuit, wherein the electromagnetic pump is supplied with AC obtained from the oscillation of DC in the frequency converter circuit, wherein the swing speed, frequency and amplitude of the swing arms vary with the oscillation frequency of the oscillator circuit, such that the suction pressure and the suction flow of the electromagnetic pump could further be changed to obtain the most appropriate pressure and flow of the mucus suction device.
US08579604B2	Floating apparatus for scroll compressors An improved floating apparatus for scroll compressors is disclosed, which is a multi-function device integrating a temperature protection mechanism, a pressure protection mechanism and a backflow-proof mechanism and therefore substantially is a floating seal member with overheating protection, high pressure protection and backflow-proof capabilities. In detail, the present disclosure provides a floating apparatus for scroll compressors that not only can be manufactured easily, but also capable of distributing the acting force resulting from the gliding block for providing better sealing effect while preventing the scroll compressors from being damaged by high temperature and high pressure.
US08579598B2	Variable capacity vane pump A variable capacity vane pump has a plurality of vanes radially extendably installed in their respective slots that are arranged in a circumferential direction in a rotor, a cam ring rockably provided on a supporting surface in a pump body and forming a plurality of pump chambers at an inner circumference side of the cam ring in cooperation with the rotor and the vanes, and a seal member provided at an outer circumference side of the cam ring and defining a first hydraulic pressure chamber located at a side where a pump discharge amount increases and a second hydraulic pressure chamber located at a side where the pump discharge amount decreases in a space outside the outer circumference of the cam ring. A center of the cam ring is offset to an inlet port side from a center of a driving shaft.
US08579593B2	Damping element for reducing the vibration of an airfoil An airfoil (10) is provided with a tip (12) having an opening (14) to a center channel (24). A damping element (16) is inserted within the opening of the center channel, to reduce an induced vibration of the airfoil. The mass of the damping element, a spring constant of the damping element within the center channel, and/or a mounting location (58) of the damping element within the center channel may be adjustably varied, to shift a resonance frequency of the airfoil outside a natural operating frequency of the airfoil.
US08579592B2	Turbofan engine A hub-side leading edge part of a fan first-stage rotating blade 10 for taking an air thereinto more extends in a forward direction of an engine than a tip-side leading edge part and a mid-span leading edge part. The hub side of the fan first-stage rotating blade 10 is integrally connected as one with the tip side and the mid span while having a longer chord length than those of the tip side and the mid span. A radius at a root of the hub-side leading edge part is set in a boss ratio of 0 to 0.4.
US08579591B2	Centrifugal compressor impeller A compressor impeller includes a hub, main blades and splitter blades. The main blades are equally spaced around the circumference of the hub. Each splitter blade is equally spaced between two adjacent main blades. Each main blade and splitter blade has suction and pressure surfaces formed in substantial compliance with normalized Cartesian coordinate values of X, Y, and Z set forth in Tables 1-4. When connected by smooth, continuing arcs, the normalized Cartesian coordinates form complete main blade and splitter blade shapes that are substantially matched by the main blade and splitter blade shapes of the compressor impeller.
US08579587B2	Method of reducing or even eliminating the vibration of a rotorcraft lift and propulsion rotor, and an airfoil assembly and a rotor implementing said method The present invention relates to a method of reducing the vibration of a lift and propulsion rotor (5) of a rotorcraft (1), the rotor having a plurality of airfoil assemblies (10) that perform rotary movement around a drive axis (AX) of the rotor (5), each airfoil assembly (10) comprising a blade (20) extending longitudinally from a root (22) suitable for being fastened to hinge means (4) of a hub (6) of said rotor (5) to a free end (21), a first distance (D1) extending between said free end (21) and said hinge means (4). In the method, said first distance (D1) is caused to vary cyclically so that the projection (TR) of the center of gravity (Cg) of a blade (20) on a horizontal plane (P) perpendicular to said drive axis (AX) and containing said hinge means (4) describes a circle.
US08579584B2	Turbofan jet engine There is a turbofan jet engine including an engine core. The engine core includes a fan and a compressor. The engine core includes a combustion chamber and a turbine functionally coupled to the compressor. The engine core includes a nozzle in fluid communication with the turbine. The turbofan jet engine includes a nacelle. The nacelle includes a forward extension proximate the fan and extending forward therefrom. The forward extension is funnel shaped to impart radial momentum to intake air during operation. The nacelle includes a vortex device disposed inside the forward extension and shaped to impart angular momentum to intake air. The vortex device includes a fixed blade extending from the interior of the forward extension and set at a rotational angle. The vortex device is shaped and positioned to direct intake air substantially perpendicular to the blades of the fan.
US08579578B2	Fan biasing transmission mechanism A fan biasing transmission mechanism includes gearbox affixed to the rear side of the housing of an electric fan's fan motor, a control rod pivotally and axially movably mounted in the gearbox. a power gear fixedly mounted on the control rod and meshed with a motor shaft worm wheel of the fan motor, a driving gear pivotally mounted in the gearbox, a gear-clutch gear fixedly mounted on the control rod and movable with the control rod into mesh with the gear-clutch gear, a first bevel gear fixedly mounted on the driving gear, a second bevel gear meshed with the first bevel gear, a bracket, a crank arm pivotally coupled between the gear shaft and the bracket, and an elastic member connected between the gear shaft and the gearbox.
US08579570B2	Fastener attaching a component to a panel A fastener includes an insert mounted in an oversized elongated aperture of a metal panel. The insert has a tubular body of lesser outside dimension than the aperture, and a hollow interior receiving a threaded stud projecting from the component. The tubular body has a flexible lip engaging the panel and first and second retaining fingers having first shoulders engaging the bottom surface of the panel and second shoulders engaging with opposed parallel extending sidewalls of the aperture to prevent rotation of the tubular body. First and second biasing fingers project from the tubular body to engage opposed curved end walls of the aperture to a bias the tubular body within the aperture as allowed by sliding of the second shoulders along the opposed parallel extending sidewalls. A plurality of ratchet fingers extends into the hollow interior to engage the stud when the stud is installed into the insert.
US08579569B2	Retaining cam for a rotary fastener A retaining cam (20) for a rotatable fastener for connecting components (16, 17) is provided. The retaining cam (20) has a housing (22) pivotally supported on a base plate (24), by which the retaining cam (20) can be fixedly connected to one (17) of the components (16, 17). A screw (30) is secured rotationally fixed in the housing (22). A fastener bolt (40) rotatably connected to another (16) of the components (16, 17) can be screwed onto the screw (30). Spring elements are associated with the screw (30) for generating an elastic pretension for securing the fastener bolt (40) against rotation. The housing (22) is pivotally supported on the base plate (24) by a spherical washer (50). An angle deviation between the center axes of the retaining cam (20) and the fastener bolt (40) can be compensated for by pivoting the retaining cam on the spherical washer (50) while maintaining full-surface contact of the retaining cam (20).
US08579566B2	Blind fastener and production method thereof This invention relates to a blind fastener having a hollow sleeve with high surface hardness and sufficient elongation, and to a novel heat treatment method therefor. The method for the heat treatment of the blind fastener includes austempering. The austempering includes a step in which a hollow sleeve of cold-rolled low carbon steel with a carbon percentage of 0.08 to 0.13% is heated and maintained from 800° C. to 950° C. during carburization, and a subsequent step in which isothermal maintenance is performed from 320° C. to 500° C. The resulting carbon percentage (CP) value is from 0.3 to 0.5%. Even in the case of a low carbon steel blind fastener, the austempering can harden the surface of the sleeve and soften the inner portion other than the surface for suitable elongation in order to provide a blind fastener having a sleeve with high surface hardness and sufficient elongation.
US08579565B2	Padded surface transportation apparatus for construction equipment A transportation rack for construction equipment is provided. The transportation rack includes a pad for supporting a hard, smooth wheel of the concrete equipment. The pad absorbs dynamic loads on the construction equipment during transportation to avoid flat spots developing on the hard, smooth wheel. The transportation rack also includes a rigid guard to protect a precisely aligned element of the equipment, and a rigid bar extending across a portion of the construction equipment to hold it down or apply a containment load to hold the equipment against the pad.
US08579563B2	Microscopic geometry cutting device including an arrival time calculator A microscopic geometry cutting device includes: a controller that outputs a timer count start command in starting a driving program which controls a drive of an X-axis or a Y-axis moving mechanism; an arrival time calculator that calculates an arrival time from when the timer count start command is output till when the cutter arrives at a machining start position in accordance with relative moving speed information of the moving mechanisms and machining start position information of a workpiece W; an elapsed time determiner that determines whether an elapsed time from when the timer count start command is output is coincident with the arrival time and outputs a trigger signal when the elapsed time is coincident with the arrival time; and a reciprocating stage driver that drives the reciprocating stage in a manner that the cutter advances and retracts in a predetermined cutting depth in response to the trigger signal.
US08579557B2	Drill [Problem] To provide a drill which enables a great reduction in cutting resistance and easy performance of a drilling operation by human power using a hand drill, a drilling machine, or the like.[Solution] A drill has two cutting edges formed symmetrically with respect to a rotation axis, and is subjected to thinning at the tip thereof. The cutting edge is configured from a thinned cutting edge (1) which extends in a shape including a curved line from a chisel edge to the outer peripheral side of the drill, and a main cutting edge (2) which extends from the end of the thinned cutting edge to the outer peripheral end of the drill when viewed from the tip side of the drill, and a thinned surface formed by the thinned cutting edge is formed into an approximately parabolic shape inclined in a drill axis direction when viewed from the front side of the drill.
US08579555B2	Hole cutter with axially-elongated aperture defining multiple fulcrums A hole cutter has a cylindrical blade body including a cutting edge and one or more axially-elongated apertures formed within a side wall of the blade body. The axially-elongated aperture is configured to receive a lever, such as a screwdriver, therethrough. Each axially-elongated aperture includes a first fulcrum axially spaced adjacent to the cutting edge, a second fulcrum axially spaced further away from the cutting edge than the first fulcrum, and optionally a third fulcrum axially spaced between the first and second fulcrums. A lever, such as a screwdriver, can be inserted into the aperture and placed against each of the fulcrums to lever slugs out of the interior of the blade body.
US08579553B2	Method and apparatus for installing cable A method of installing cable through material, for example, concrete, wood, masonry, plastic steel, or the like comprising a drill bit with a distal end having a hollow tip with an attachment mechanism for receiving the cable. The drill bit is drilled through the material, and left in place while the cable is attached to the proximal end of the drill bit. There is no need to remove the drill bit from the aperture or material to attach the cable thereto. After attachment to the drill bit, the cable is inserted through the aperture with the drill bit and removed from the drill bit after it passes through the material so it can be attached to a receiver device.
US08579549B2	Reinforced ground structure, and siding elements for constructing same The invention relates to a structure including a fill (1), reinforcing strips (2), and facing (3), the reinforcement strips (2) being anchored to the facing (3). The facing incorporates a path formed for a reinforcement strip (2) between two emergence points (PE1, PE2) that are located at the back surface (7) of the facing, wherein the path comprises: two adjacent portions (21, 22) that are placed so as to position each strip within an emergence plane (P1, P2); two curved portions (23, 24) provided as extensions of the two adjacent portions (21, 22) and arranged so as to deviate the strip out from the emergence planes (P1, P2); and a connecting portion connecting together the two curved portions (23, 24). In the structure, both emergence planes (P1, P2) are distinct and separated by a physical separator, and the connecting portion includes at least one loop (25) located outside the emergence planes (P1, P2) and outside the space between said emergence planes. The invention also relates to a related facing element.
US08579539B2	Dairy freestall cross clamp assembly A dairy animal freestall cross clamp assembly including a first clamp portion defining a first recess, the first recess having a first axis; a second clamp portion releasably joined to the first clamp portion and defining a second recess, the second recess having a second axis that is not parallel to and intersects with the first axis; and an insert disposed between and joined to the first clamp portion and the second clamp portion, the insert defining a first pocket opposing the first recess, and a second pocket for opposing the second recess. The insert can be resilient to avoid crushing of rail members and resist impact loads.
US08579534B2	Page alignment device for scrapbooking A scrapbooking page alignment device for temporarily aligning at least two adjacent scrapbook pages having retention receivers extending from their respective spine edges, the device comprising (i) a base; and (ii) two or more spaced retention posts extending from said base; where said retention posts are dimensioned to temporarily receive the retention receivers of the two adjacent scrapbook pages.
US08579532B2	Dosing device comprising a monolithic, resilient roll A dosing device with a monolithic, resilient roll meters liquid detergent, softener, concentrates, cleaning agents, and other medium-viscosity liquids. The rolling application element is used for applying detergent to very dirty fabric areas. The monolithic roll (3) encompassing a shaft (5) and an outer jacket (6) with plastic recesses is inserted into a mount (1) of a dosing receptacle (2). Radially extending spring lamellae are molded between the shaft (5) and the outer jacket (6).
US08579529B2	Multi-unit cosmetic applicator A multi-unit cosmetic applicator comprising: a housing body, a first cosmetic unit housed in the housing body, a second cosmetic unit housed in the housing body, an opening in the housing, wherein each cosmetic unit has a means for being independently movable relative to each other from a stored position to an advanced position and back to its stored position.
US08579521B2	Pluggable optical transceiver having electrically shielded receptacle, and optical connector installed therein A pluggable optical transceiver is disclosed. The optical transceiver includes a resin made optical receptacle to receive an external connector, a housing that provides an area for setting the optical receptacle, and an electrically conductive sheet put between the rear of the optical receptacle and the wall forming the area. The rear wall of the optical receptacle provides a step for receiving a flange of a sleeve assembly set in the optical receptacle.
US08579518B2	Optical receptacles and systems and devices including optical receptacles According to one embodiment, an optical receptacle for receiving a corresponding optical connector may include a receptacle housing, a receptacle optical path and a positionable shutter assembly. The receptacle housing includes a connector port disposed at an end of the receptacle housing and a receptacle pathway. The connector port may receive the corresponding optical connector. The receptacle optical path may terminate within the receptacle housing and includes an optical waveguide. The positionable shutter assembly includes a cleaning member positioned on a support surface of the positionable shutter assembly. The positionable shutter assembly may be biased to the closed position such that the cleaning member contacts or is proximate to the optical waveguide and the positionable shutter assembly is disposed in the receptacle pathway. The positionable shutter assembly may be biased to the open position such that the cleaning member is not positioned over the receptacle optical path.
US08579516B2	Roller cage for a rolling bearing, particularly a double roller cage for a cylinder rolling bearing, rolling bearing, and method for producing a roller cage for a rolling bearing A roller cage for a rolling bearing, particularly a double roller cage for a cylinder rolling bearing, which has a ring web with axially extending webs. Every two adjacent webs delimit a receptacle pocket for a rolling element with a floor thereof being formed by the ring web. Each web has a radial outer and inner base side connected to each other by an axial outer face side. The face side of the radial outer base side is tapered toward the radial inner base side. To increase the rigidity of the webs with regard to trouble-free removal and installation of the rolling bearing, the radial inner base side is trapezoidal such that a web width of the radial inner base side increases from the face side to the floor of the receptacle pocket.
US08579515B2	Form-coupling arrangement in a bearing ring for a motor vehicle wheel A bearing ring (10) has a tubular steel core (15) around which is formed an outer body (16) of lightweight material. The outer surface of the core forms a circumferential shoulder (26), a first side of which is subjected to a turning finishing process and provides an undercut surface (23) defining part of an annular groove (22). An axially opposite, second side of the shoulder (26), not subjected to a turning finishing process, has a non-circular portion (29) with radial recesses (28) that act as anti-rotation means cooperating with complementary portions formed by the outer body (16).
US08579514B2	Press fitting a cartridge bearing An apparatus and associated method involving an actuator assembly having an actuator body defining a bore and a bearing assembly in the bore. The bearing assembly has a shaft, and further has a bearing having an inner race that is affixed to the shaft and an outer race that is rotatable relative to the inner race. The bearing also has a sleeve defining an annular rigid portion circumscribing the outer race and affixed thereto. The sleeve further defines an annular predictably deformable portion depending from the rigid portion that is entirely disposed longitudinally distant from the outer race and sized to deform when press fit into the bore to operably align the shaft in the bore.
US08579512B2	Drive unit for motor vehicles having an electrical motor A drive unit for motor vehicles which has at least one electrical motor and at least one transmission assembly. The electrical motor and the transmission assembly are operatively connected to one another by at least one shaft and the shaft is rotatably mounted by at least one first rolling bearing which sits in a rotary union for the shaft in the transmission assembly.
US08579505B2	Temperature indication structure of a non-mercury non-electronic clinical thermometer A temperature indication structure for a thermometer includes a temperature indication portion made of a heat conductive layer to receive a heat flow. A structure with temperature indication markings is disposed on or above the temperature indication portion. A reversible temperature-sensitive color changing layer is formed on the temperature indication portion to overlap the structure of the temperature indication markings. The heat conductive layer is adapted to conduct the heat flow to the reversible temperature-sensitive color changing layer, producing a sensed temperature and a color changing zone of the reversible temperature-sensitive color changing layer in response to the sensed temperature thereby exhibiting a corresponding temperature value.
US08579504B2	Subsea and landing string distributed temperature sensor system A line is deployed along a landing string or along a marine riser of a subsea well. The line has sensors, such as temperature sensors, distributed along its length. In one embodiment, the line comprises a fiber optic line that includes fiber optic temperature sensors distributed along its length. In another embodiment, the line comprises a fiber optic line used to transmit light, wherein the returned back-scatter light is analyzed to provide a temperature profile along the length of the fiber line. The fiber optic line can be deployed by connecting it to the landing string, pumping it down a pre-existing conduit (such as a hydraulic or chemical injection conduit), or pumping it down a dedicated fiber optic specific conduit.
US08579498B2	High efficiency escapement A mechanical device for horology, comprising angular reduction means apt to decrease the oscillation of the width of the lever pacing the motion of the gear.
US08579496B2	Stand mixer wiping beater A mixing beater for a small appliance includes a metallic frame including an arm; a rigid plastic shell extending over the arm; and only one scraper. The scraper extends over the rigid plastic shell and has a flexible blade configured to contact an inner surface of a mixing bowl when viewed in a first plane.
US08579494B2	System and method for dough extrusion A system and method for extrusion of dough is disclosed. The system includes an auger for moving the dough; a metering pump comprising an input; a first motor for actuating the auger to transfer dough to the input of the metering pump; a first encoder for reading a position or speed of the first motor and for transmitting a signal associated with the position or speed of the first motor; and a controller configured to receive the signal from the first encoder to control operation of the first motor. The controller operates the first motor to at least partially counteract a variance in a pressure of dough at the metering pump based signals from the encoder and/or the pressure sensor.
US08579492B2	Optical film having microreplicated structures and methods An optical film for use in transparent displays, such as reflective LCDs. The optical film has three-dimensional, prismatic structures that reflect incoming light. The prismatic structures are configured so that the reflecting facets orient the reflected light in desired reflective light pattern. The pattern shape and intensity can be controlled by the shape and dimensions of the various reflecting facets. In one embodiment, the height of the prismatic structure varies along two dimensions of the structure.
US08579491B2	Backlight unit and display apparatus having the same A display apparatus includes a light guide plate, a light source unit and a display panel. The light guide plate includes an incident surface, an exit surface and an opposite surface opposite to the exit surface and guides a light incident into the incident surface toward the exit surface. The light source unit includes a light source which generates light and is disposed adjacent to the incident and has an emitting surface inclined with respect to the incident surface. An extension line of a normal line of the emitting surface passes through the opposite surface, and the light is incident into the incident surface while being inclined toward the opposite surface. The display panel displays an image by receiving the light emitted from the exit surface.
US08579490B2	Backlight device and display device provided with the same Provided is a backlight device which can suppress deterioration of uniformity. The backlight device (10) is provided with an LED (11), and a light guide plate (12) which includes a light incoming surface (12a) and a light outgoing surface (12b). An inclined surface (12c) which is inclined from the light outgoing surface is formed between the light incoming surface and the light outgoing surface of the light guide plate, and the light guide plate is formed such that the thickness of a portion on the light incoming surface side is more than that of a portion on the light outgoing surface side. At the front of the portion on the light incoming surface side of the light outgoing surface of the light guide plate, a regulating member (13), which has a light blocking characteristic and regulates shift of the light guide plate in the thickness direction of the light guide plate, is arranged.
US08579487B2	Lighting module A lighting module is provided. The lighting module comprises a circuit board, a first light source array, a second light source array, and a plurality of first light guides. The first light source array is disposed on the circuit board and comprises a plurality of first solid light emitting semiconductors providing a first light with a first wavelength. The second light source array is disposed on the circuit board and comprises a plurality of second solid light emitting semiconductors providing a second light with a second wavelength. The first light guides are disposed on the circuit board and between the second solid light emitting semiconductors. The second solid light emitting semiconductors are located on a side of each of the first light guides, respectively, so that the second light emitted by the second solid light emitting semiconductors enters the first light guides to be uniformly emitted.
US08579486B2	Vehicular headlamp apparatus including a semiconductor light-emitting element and a reflector A vehicular headlamp apparatus includes: a lamp body; a translucent cover having a slanted portion; and a lamp unit. A semiconductor light-emitting element is mounted on a mounting surface so that its irradiation axis intersects with lamp unit's optical axis. Reflector's reflective surface reflects light from the semiconductor light-emitting element toward a vehicle front. One end of the reflective surface is located on a vehicle rear side of the light-emitting element. The other end protrudes toward a vehicle front from a front side end of the mounting portion. The reflective surface has a portion protruding toward the vehicle front from the front side end to face the slanted portion. Within a light distribution pattern, rays of light reflected by first area, second area adjacent to the first area and third area on the reflective surface respectively form a horizontal cut-off line, an oblique cut-off line and a diffusion portion.
US08579485B2	Vehicular lamp A vehicular lamp includes a light source disposed on an optical axis extending in a front-back direction of the vehicular lamp; and a reflector that reflects forward light from the light source. The reflector is formed by a translucent member including a plurality of optical elements disposed continuously in a radial direction of the optical axis. Each of the optical elements includes: a surface of incidence through which light from a light emission reference point in the light source is incident into the optical element and which refracts the light into a direction away from the optical axis, a reflective surface which internally reflects forward the light which is incident into the optical element through the surface of incidence, and a surface of emission through which the light internally reflected by the reflective surface is emitted forward from the optical element. The reflective surface of each of the optical elements is formed by a curved surface formed to allow generally an entirety of the light internally reflected by the reflective surface to reach the surface of emission of the optical element as substantially parallel light.
US08579480B2	LED landing light arrangement for an aircraft An LED landing light arrangement for an aircraft comprises a plurality of LED light sources (12,14,16) for arrangement on an aircraft (24), primarily on the wing roots (20), on the front edges of the wings (22) and/or on the landing gears (18). The LED light sources (12,14,16) are operative to generate, relative to the central axis of the aircraft (24), a light distribution (10) ahead of the aircraft (24) that is spread substantially in a Y-shaped configuration in an obliquely downward direction. The light distribution (10) comprises two converging lateral regions (34,36) arranged laterally ahead of the aircraft (24), and a central region (40) running from said converging lateral regions (34,36) along an extension of said central axis and oriented in a direction away from the aircraft (24).
US08579477B2	Electronic device An electronic device is provided. The electronic device includes a body, a light source, a light shutter, and a light transmissive net structure. The body has a cavity therein. The light source is disposed in the cavity. The light shutter is disposed over the light source, wherein the light shutter includes a light transmissive pattern therein. The light transmissive net structure is disposed over the cavity and covers the light shutter. In use, light emitted from the light source would pass through the light transmissive pattern to the light transmissive net structure, thereby displaying an image corresponding to the light transmissive pattern onto the light transmissive net structure.
US08579474B2	Bézier curve reflector, light source arrangement and projector apparatus A reflector may have a reflective surface, wherein the contour of the reflective surface is traversed by a Bézier curve.
US08579473B2	Luminaire for indirect illumination The invention relates to a luminaire (2) and an illumination system (12). The luminaire according to the invention comprises a light exit window (30) for emitting light from the luminaire, and a reflective screen (40) arranged opposite the light exit window. The luminaire further comprises a light source (20) which is arranged for indirect illumination of the light exit window via the reflective screen. The light source is arranged near the light exit window on an imaginary plane P substantially parallel to the light exit window and emits light away from the light exit window. The luminaire further comprises a specularly reflective part (43) as part of the reflective screen, which specularly reflective part is concavely shaped for reflecting at least part of the light emitted by the light source towards a diffusely reflective part (42) of the reflective screen.The luminaire according to the invention has the effect that use of the specularly reflective part allows an improved controlled reflection of the portion of the light emitted by the light source towards the diffusely reflective part.
US08579470B1	LED illumination source with improved visual characteristics An illumination source is disclosed that features, in one embodiment, an at least generally conical body extending outward along an axis of illumination, a socket supported with respect to the body having a pair of connector surfaces for receiving power and having an axis of insertion at least generally parallel to the axis of illumination, and one or more LED illumination elements supported with respect to the body such that at least a portion of their illumination axes are at least generally parallel to the axis of illumination of the source. A power supply has electrical inputs operatively connected to the socket and electrical outputs operatively connected to the LED illumination elements, and a front face is positioned opposite the socket along the illumination axis. An optical light-directing element is provided separate from any optical process or packaging surfaces built onto the LEDs, is disposed between the LED illumination elements and the front face, and has medial and distal ends, with the distal end being spaced away from the front face.
US08579468B2	Semiconductor light-emitting element mounting module, semiconductor light-emitting element module, semiconductor light-emitting element light fixture, and manufacturing method of semiconductor light-emitting element mounting module A semiconductor light-emitting element mounting module includes a conductive plate including semiconductor light-emitting fixing portions and first and second electrical-supply segments, wherein the semiconductor light-emitting fixing portions includes first and second conductive sections in contact with one end of first and second contacts, the other end of the first and second contacts is conductive with an anode and a cathode of an light-emitting element, a pair of the first and second electrical-supply segments are electrically conductive with the first and second conductive sections at one end of the conductive plate, and the other pair of the first and second electrical-supply segments are conductive with the first and second conductive sections at other end of the conductive plate; and a resin surface-insulation portion covering the conductive plate with the other end of the first and second contacts exposed, and with the first and second electrical-supply segments exposed.
US08579466B2	Illumination apparatus and methods of forming the same In one aspect, an illumination apparatus includes a waveguide, embedded in which are a light-emitting source and a photoluminescent material. Output light is emitted from at least a portion of a first surface of the waveguide. The photoluminescent material includes nano-size phosphor particles and/or quantum dots.
US08579465B2	Plant growing system A plant growing system of the present invention includes: a first light source for irradiating red light to a plant; a second light source for irradiating far-red light to the plant; a control part that controls irradiation operations of the first light source and the second light source; and a time setting part that sets a time zone in which the control part operates the irradiation of the first light source and the second light source. The time setting part is designed such that the first light source starts red light irradiation before sunset; and the second light source starts far-red light irradiation after the red light irradiation.
US08579464B2	Illumination arrangement, multiple light module, luminaire and use thereof An illumination arrangement comprising a plurality of light-emitting semiconductor components (1), arranged in a row, a diffuser (2), which is illuminated by the light-emitting semiconductor components during operation of the illumination arrangement, intermixes light emitted by the semiconductor components during operation and has a light coupling-out area (200) remote from the semiconductor components, and two mutually opposite, reflective longitudinal side faces (3), between which the row of light-emitting semiconductor components is arranged, which run perpendicular or obliquely with respect to the light coupling-out area, and which reflect at least part of the light emitted by the light-emitting semiconductor components during operation in the direction toward the light coupling-out area.
US08579463B2	Modular lighting system An LED tube is provided for providing general illumination. The LED tube includes a tubular housing having a clear shield and a heat sink opposite the clear shield. A strip including LED lights, circuitry, and electrical hubs are positioned on the backside of the heat sink under the shield. The housing also includes first and second ends that include portions of a quarter turn locking system to allow multiple housings to be attached to one another for a longer string of lighting. A power source for powering the LED lights, and an end cap may also be attached to the first and second ends of the housing by the quarter turn locking system. The housing or housings may be connected to a wall or the like by the use of one or more clip mounts.
US08579461B2	Rechargeable flameless candle systems and methods According to embodiments of the present invention, a recharging device includes a recharging port that receives a flameless candle and recharges a battery in the candle. The recharging device includes a first stacking structure that has a top portion and a bottom portion. There is a top stacking contact on the top portion. The electrical power bus is connected with the top stacking contact. The top portion of the first stacking structure is configured to mate with a bottom portion of a first stacking structure of another recharging device. In an embodiment, the bottom portion of the first stacking structure has a bottom stacking contact electrically connected with the electrical power bus. The bottom stacking contact may have a pogo spring. The recharging device may also have a second stacking structure having a top portion without an electrical contact. The second stacking structure is configured to mate with a bottom portion of another second stacking structure. In an embodiment, the device has two first stacking structures and two second stacking structures.
US08579460B2	LED flare and system A LED flare and system for use to provide greater visibility in any light conditions, particularly in low light. The flare comprises an elongated housing that is generally cylindrical with a flat side. It has a handle at one end and a plurality of LEDs positioned along the outer periphery. A switch located on the elongated housing operates the flare. The flare also includes a re-chargeable battery encased in the housing for powering the flare and a circuit for delivering power and operational control from the battery to the LEDs upon activation by the switch. A set of contacts positioned on the outside of the housing deliver a charge to the battery. The flare includes an attachment device for holding an external charger in place against the contacts during charging operation. An individual flare may be part of a system that also includes other flares and a carrying case with an integrated charger, one or more flare stands and charger accessories.
US08579458B2	Fitting member, leaf spring and lighting apparatus A V-shaped leaf spring is provided, at one side of the leaf spring, with a plurality of pressing parts curved convexly toward the other side thereof and arc-shaped in cross section along a longitudinal direction of the leaf spring. The leaf spring is appropriately attached to a lighting apparatus main body so that a region of the leaf spring at a bent part thereof is located downward. Thus, upon installation of the lighting apparatus main body into an attachment hole provided in a ceiling, either one of the plurality of pressing parts abuts against the ceiling having different thicknesses from above, and a sufficient downward pressing force can be exerted on the ceiling having different thicknesses, thereby allowing the component to be fixed to the ceiling with a sufficient holding force.
US08579456B2	Backlight unit In order to accurately illuminate an object to be illuminated with planar light having little unevenness in intensity, a backlight unit (2) having a simple structure and simple assembly is provided with a reflection sheet (8) which covers a chassis (5) and a substrate (6) and which has through-holes (81) penetrated by light sources (7), wherein the through-holes (811) formed in the center become larger than the through-holes (814) formed at the edges.
US08579452B2	User interface and method for control of light systems An interface device (100) for controlling light sources (110) includes a target region (205); and a controller (120) that associates a preset with an illumination region, and controls a light source (110) in the illumination region when an indicator (215) associated with the preset and illumination region is moved into the target region (205). The controller (120) associates the preset with the illumination region when the preset is moved to an area of the interface device (100) associated with the illumination region. The controller (120) is further configured to change light attributes of light emitted from the light source (110) when the indicator (215) is moved across the target region (205), such as providing maximum intensity when the indicator (215) is at the center of the target region (205). The light attributes include intensity, color, hue, saturation, beam direction and/or beam width of the light.
US08579449B2	Pointer type measuring instrument Disclosed is a pointer type measuring instrument of a novel look, in which an indication portion detours the outer circumference of a display portion and can be visually confirmed as if the indication portion is floating above the display portion. The pointer type measuring instrument (M) comprises a display means (1), a drive body (2) mounted on the back side of the display means (1), an arm portion (3) mounted on the output shaft (26) of the drive body (2) and detouring the outer circumference of the display means (1), an indicating portion (5) extending from the arm portion (3) toward the center of the display means (1) and indicating an indicator portion (4) disposed on the display means (1), and a first light source (7) mounted on the arm portion (3) or the indicating portion (5) and causing the indicating portion (5) to glow.
US08579447B2	Light control grid for close work When placing a photographic subject close to a large light source equipped with a light control grid, the problem of occluded light channels is solved by variably converging the channels, such that the soft light is directed at a focal point that can be as close as one-half the diagonal dimension of the light source. The light channels are formed by generally planar intersection of strips, the strips preferably made of a flexible fabric material and having slots with corresponding slots on other strips. Optionally, a deployable frame may be provided to help support the grid.
US08579445B2	Plastic glass mounting and retention device A plastic mirror mounting system is proposed with a substrate made of plastic material coated with at least one reflective layer on a first surface. The plastic material has means to be connected to a mounting structure on the second surface of the plastic glass mirror. The plastic substrate includes at least three plastic mirror clips having at least one shoulder of plastic mirror clip that has a distance from the second surface so that no or almost no stress disturbs the reflective surface.
US08579444B2	Modular rear view mirror and method to assemble it The invention is related to a rear view mirror assembly with a least two parts out of the group of part as: mirror frame, mirror base, mirror housing, mirror bezel, mirror glass, mirror lighting means, actuator, that must be connected during assembly process with at least one retention latch. This retention latch comprises a circular hood and a rectangular arm formed in a first part and to be inserted into an opening and shifted along a slot in a second part.
US08579443B2	Scanned beam display having a redirected exit cone using a diffraction grating Briefly, in accordance with one or more embodiments, a scanned beam display, comprises a light source to generate a beam to be scanned and a scanning platform to scan the beam into an exit cone. The scanning platform receives the beam at a selected feed angle, and the scanning platform has a surface structure to redirect the exit cone at an exit angle that is less than the feed angle.
US08579442B2	Advertisement content selection and presentation Systems, devices and methods that enable advertisement on mobile computing applications are provided. More specifically, described herein are devices and methods that are capable of delivering relatively more friendly advertising information to a user while causing less interference on graphics-based user interfaces of such devices. Integral projector modules which may be embedded in mobile computing devices are also provided. These modules may be capable of externally projecting advertising content upon most any surface.

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