Document | Document Title |
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US08575480B2 |
Connection assembly
A connection assembly for securing electrical components used with power equipment comprises a housing and connector cover forming an upper arrangement of the connection assembly. The housing and connector cover form a cavity therebetween for supporting electronics disposed within the cavity. The connection assembly also comprises a lower arrangement used to secure the connection assembly to a surface of a power equipment device and a hinge assembly that forms a rotational connection between the upper arrangement and the lower arrangement. |
US08575478B2 |
Integrated structure of CIS based solar cell
In an integrated structure of a CIS based thin film solar cell obtained by stacking an light absorbing layer, a high-resistance buffer layer, and a window layer in that order, a first buffer layer adjoining the light absorbing layer is made of a compound containing cadmium (Cd), zinc (Zn), or indium (In), a second buffer layer adjoining the first buffer layer is made of a zinc oxide-based thin film, a third buffer layer is formed to cover the end face exposed by forming an interconnect pattern in the light absorbing layer, the first buffer layer, and the second buffer layer and the top end surface of the second buffer layer, and the third buffer layer is made of a zinc oxide-based thin film. |
US08575475B2 |
Solar cell module with rear contacts
A solar cell module with a simple configuration and high efficiency is provided. A solar cell module of the present invention is configured by electrically connecting a plurality of solar cell elements. Each of the plurality of solar cell elements includes a plurality of first connection parts representing wiring connection parts in a first electrode and a plurality of second connection parts representing wiring connection parts in a second electrode on the same surface. A first solar cell element and a second solar cell element arranged adjacent to each other have portions of the plurality of first connection parts of the first solar cell element and the plurality of second connection parts of the second solar cell element connected by a wiring having a linear form in plan view. |
US08575472B2 |
Photoelectric conversion device and method for producing same
In order to increase photoelectric conversion efficiency in a photoelectric conversion device, there is disclosed a photoelectric converter containing a photoelectric conversion unit in which a p-type layer (40) containing a p-type dopant, an i-type layer (42) that is a microcrystalline silicon layer that is an electricity-generating layer, and an n-type layer (44) containing an n-type dopant are layered, wherein the p-type layer (40) is caused to have a layered structure comprising a first p-type layer (40a) that is a microcrystalline silicon layer, and a second p-type layer (40b) containing at least one of an amorphous silicon carbide p-type layer and an amorphous silicon p-type layer disclosed between the microcrystalline silicon p-type layer (40a) and the i-type layer (42). The second p-type layer (40b) is provided with an oxide layer on the side of the i-type layer (42). |
US08575470B2 |
Integrated panel with skylight, ventilation, solar hot water system and solar photovoltaic/lighting system
An integrated alternative energy roofing panel incorporates an array of solar concentrator tubes interconnected with transparent web to form a joined plate supported in frame elements with an attached working fluid manifold. The working fluid in the manifold is operatively in contact with the solar concentrator tubes for transferring heat from the tubes. In one exemplary construction, each of the solar concentrator tubes terminates in a conducting metal sleeve which extends beyond the frame element into the manifold. A safety glass panel is attached to one frame element beneath the joined plate. The joined plate and safety glass panel may be sealed to the frame elements to form a chamber and the chamber may be evacuated. A plurality of light emitting diodes (LEDs) are embedded in the web for supplemental lighting. An array of photovoltaic cells mounted to a top surface of the manifold and a battery are interconnected for powering the LEDs. The manifold incorporates a compartment to house the battery as a portion of the integrated panel. |
US08575469B2 |
Thermoelectric conversion module and method for manufacturing the same
A compact, high-performance thermoelectric conversion module includes a laminate having a plurality of insulating layers, p-type thermoelectric semiconductors and n-type thermoelectric semiconductors formed by a technique for manufacturing a multilayer circuit board, particularly a technique for forming a via-conductor. Pairs of the p-type thermoelectric semiconductors and the n-type thermoelectric semiconductors are electrically connected to each other in series through p-n connection conductors to define thermoelectric conversion element pairs. The thermoelectric conversion element pairs are connected in series through, for example, series wiring conductors. The thermoelectric semiconductors each have a plurality of portions in which the peak temperatures of thermoelectric figures of merit are different from each other. These portions are distributed in the stacking direction of the laminate. |
US08575467B2 |
Generator of electric energy based on the thermoelectric effect
A generator of electric energy based on a thermoelectric effect includes a layer of thermoelectric material set between two pipes that guide two flows of fluid at temperatures different from one another. Each of the pipes has its wall in heat-conduction contact with respective side of the layer of thermoelectric material. Each pipe has a cavity of passage for the respective flow of fluid occupied by a porous material or divided by diaphragms into a plurality of sub-channels so as to obtain a large heat-exchange surface between each flow of fluid and the wall of the respective pipe and between said wall and the respective side of the layer of thermoelectric material. |
US08575464B1 |
Curved tremolo arm
A tremolo bar formed as a single curved rod having a handle portion with a first curved U-shaped loop, a second U-shaped loop, and a root portion for attachment of the root portion to a bridge system of a guitar. The U-shaped loops provide a secure means for a user to hold and operate the handle portion with one or more fingers continuously while playing the strings of the guitar without interference from the holding and operating of the handle. A user can insert or hook a finger into the loops to hold and operate the handle. The looped handle eliminates the need for the user to grasp and release the handle repeatedly during the course of picking and strumming the strings while performing. |
US08575463B1 |
Maize variety inbred PHW6G
A novel maize variety designated PHW6G and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHW6G with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHW6G through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHW6G or a locus conversion of PHW6G with another maize variety. |
US08575456B1 |
Maize variety hybrid X90B029
A novel maize variety designated X90B029 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X90B029 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X90B029 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X90B029, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X90B029. This invention further relates to methods for producing maize varieties derived from maize variety X90B029. |
US08575454B1 |
Maize variety hybrid X95A825A
A novel maize variety designated X95A825A and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X95A825A with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X95A825A through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X95A825A, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X95A825A. This invention further relates to methods for producing maize varieties derived from maize variety X95A825A. |
US08575439B2 |
Melon hybrid SVR 17391044 and parents thereof
The invention provides seed and plants of melon hybrid SVR 17391044 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of melon hybrid SVR 17391044 and the parent lines thereof, and to methods for producing a melon plant produced by crossing such plants with themselves or with another melon plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants. |
US08575432B2 |
Disease resistant plants
The present invention relates to a plant, which is resistant to a pathogen of viral, bacterial, fungal or oomycete origin, wherein the plant has an increased homoserine level as compared to a plant that is not resistant to the said pathogen, in particular organisms of the phylum Oomycota. The invention further relates to a method for obtaining a plant, which is resistant to a pathogen of viral, bacterial, fungal or oomycete origin, comprising increasing the endogenous homoserine level in the plant. |
US08575430B2 |
Hybrid artichoke variety NUN 4006 AR
The invention provides a new and distinct hybrid variety of globe artichoke, NUN 4006 AR or Symphony F1, which is characterized by producing high quality, green heads for the fresh market and/or the processing industry. |
US08575426B2 |
Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
US08575425B2 |
AXMI-205 pesticidal gene and methods for its use
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 3, or 4, the nucleotide sequence set forth in SEQ ID NO:1, 9, 10, or 11, as well as variants and fragments thereof. |
US08575424B2 |
Production of functionalized linear DNA cassette and quantum dot/nanoparticle mediated delivery in plants
Methods for introducing a functionalized linear nucleic acid cassette molecule of interest into a plant cell comprising a cell wall include use of nanoparticles. In some embodiments, the cell comprising a cell wall is a cultured plant cell. Methods include genetically or otherwise modifying plant cells and for treating or preventing disease in any plant, especially crop plants. Transgenic plants include a nucleic acid molecule of interest produced by regeneration of whole plants from plant cells transformed with functionalized linear nucleic acid cassette molecules. |
US08575421B2 |
Plants having enhanced yield-related traits and a method for making the same
The present invention relates generally to the field of molecular biology and concerns a method for enhancing various yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding a TCP1 transcription factor. The present invention also concerns plants having modulated expression of a nucleic acid encoding a TCP1 polypeptide, which plants have enhanced yield-related traits relative to corresponding wild type plants or other control plants. The invention also provides constructs useful in the methods of the invention. |
US08575420B1 |
Maize variety hybrid X00B130
A novel maize variety designated X00B130 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X00B130 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00B130 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00B130, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00B130. This invention further relates to methods for producing maize varieties derived from maize variety X00B130. |
US08575415B2 |
Process and composition for the immobilization of high alkaline radioactive and hazardous wastes in silicate-based glasses
The present invention provides processes to immobilize high alkaline radioactive and/or hazardous waste in a silicate-based glass, the waste containing one or more of radionuclides, hazardous elements, hazardous compounds, and/or other compounds. The invention also provides silicate-based glass compositions for use in immobilizing radioactive and/or hazardous waste. |
US08575413B2 |
Process for the alkylation of benzene with isopropanol or blends of isopropanol and propylene
The invention relates to a process for the alkylation of benzene with isopropanol (IPA) as alkylating agent, or blends of isopropanol and propylene, which comprises effecting said reaction completely in gaseous phase and in the presence of a catalytic system containing a zeolite belonging to the MTW family. |
US08575410B2 |
Process for oligomerizing dilute ethylene
The process and apparatus converts ethylene in a dilute ethylene stream that may be derived from an FCC product to heavier hydrocarbons. The catalyst may be an amorphous silica-alumina base with a Group VIII and/or VIB metal. The catalyst is resistant to feed impurities such as hydrogen sulfide, carbon oxides, hydrogen and ammonia. At least 40 wt-% of the ethylene in the dilute ethylene stream can be converted to heavier hydrocarbons. |
US08575400B2 |
Therapeutic compounds
A (−)-stereoisomer of formula (I): wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful in the treatment or prevention of nausea and vomiting or for promoting an antiemetic effect. |
US08575397B2 |
Derivatisation of biological molecules
The present disclosure relates to a new polymerization process in which ethylenically unsaturated monomers are polymerised by a living radical polymerization process in the presence of an initiator and a catalyst. Polymers produced by this new process are also thought to be novel and may be used to derivatise biological molecules to improve their efficacy as therapeutic treatments. A preferred polymer is of formula The polymers are particularly suitable for derivatising proteins, such as interferon-α. |
US08575396B2 |
Low-VOC polyamino alcohols
A method for producing a polyamino-polyalcohol. The method comprises steps of: (a) combining an aminoalcohol of formula (I) with a nitro-diol of formula (II) to produce a nitro amino diol; and (b) contacting the nitro amino diol with a reducing agent capable of reducing aliphatic nitro groups. |
US08575391B2 |
5-substituted-2-phenylamino benzamides as MEK inhibitors
An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases.The compounds of the present invention and pharmaceutically acceptable salts thereof are represented by the following formula (1): [where R1, R2, R3, R4, and X are the same as defined in the present patent application]. |
US08575390B2 |
Branched succinimide dispersant compounds and methods of making the compounds
In accordance with the disclosure, one aspect of the present application is directed to a dispersant compound comprising the reaction product of (i) a hydrocarbyl carbonyl compound, (ii) a polycarbonyl compound having at least three carbonyl acylating functions, and (iii) a primary amine moiety of a polyamine. Methods of making and methods of using the dispersant compound are also disclosed. |
US08575389B2 |
Neutralization process
The invention relates to a continuous neutralization process in which at least one ethylenically unsaturated carboxylic acid is neutralized at least partly with a base and the temperature of the neutralized solution is less than 70° C., and also to an apparatus for carrying out the process. |
US08575388B2 |
Method for producing methacrylic acid
The present invention relates to a method for producing methacrylic acid by reacting methacrylamide with water, wherein said reaction is performed continuously in a tube reactor and a pressure differential exists in the flow direction of the reaction mixture inside said tube reactor. Furthermore, the present invention discloses a facility for carrying out the method according to the invention. |
US08575387B2 |
Method for preparing carboxylic acids
The present invention relates to a method for preparing carboxylic acids comprising the step of contacting an aromatic hydrocarbon comprising at least one group including an α C-atom that is oxidizable to a carboxylic group in liquid phase with an oxygen containing gas in the presence of a heterogeneous catalyst with perovskite structure ABO3 with A being selected from at least one element of groups 1 to 3 of the Periodic Table, lanthanides or actinides, and B being selected from at least one element of the groups 4 to 15 of the periodic table or an oxygen-defective derivative of that catalyst having the formula ABO3−δ with 0<δ<1. |
US08575386B2 |
Fragrance compounds
A method of providing a fragrant odor to an application, comprising the addition thereto of at least one compound of the formula I wherein X and Y are independently selected from the group consisting of —CR1R2R3, —NR4R5 and —OR6, wherein R1 to R5 are selected from H and essentially hydrocarbon moieties that optionally comprise at least one oxygen, nitrogen or silicon atom, and R6 is selected from essentially hydrocarbon moieties that optionally comprise at least one oxygen, nitrogen or silicon atom; and, A is an essentially hydrocarbon moiety that optionally comprises at least one oxygen, sulphur, nitrogen or silicon atom, with the proviso that the compound A-CHO is a fragrant aldehyde. The use of these compounds in laundry, household and personal care products confers a long-lasting freshness. |
US08575385B2 |
Process of making optically pure melphalan
This invention provides a process of making optically pure melphalan of the formula by hydroxyethylation, in a regioselective manner, of the aromatic amino group rather than the glycinic amino group. |
US08575384B2 |
Silanol-containing triarylamine derivatives
Provided are triarylamine derivatives excellent in compatibility with various organic solvents or resins, capable of forming a silicon-oxygen bond on the surface of an inorganic material, and allowing easy purification; a preparation process of the triarylamine derivative; an intermediate product of the triarylamine derivative; an inorganic composite material obtained by bonding the triarylamine derivative to the surface of an inorganic material; and a preparation process of the inorganic composite material. |
US08575380B2 |
Branched polyethylene glycol linked with diacyl glycerol, process for producing the same, and polyethylene glycol modified liposome
Provided is a polyethylene glycol derivative which contains two PEG chains, which is bound to a diacylglycerol, which has high purity, and which enhances the stability of liposomes. Polyethylene glycol is represented by the following formula (1) and which is bound to a diacylglycerol: In Formula (1), R1 is a hydrocarbon group containing 1 to 7 carbon atoms, R2 is an alkyl or alkenyl group containing 9 to 21 carbon atoms, n is the average number of moles of added polyethylene glycol chains, 10≦n≦100, and X is a linker site between branched polyethylene glycol and the diacylglycerol and is represented by the following formula (2): —(CH2)l-Y—(CH2)m- (2) In Formula (2), Y is an ether bond, an ester bond, a urethane bond, an amide bond, or a carbonate bond and l and m are an integer of 0 to 6. |
US08575372B2 |
Isosorbide derivatives
Disclosed are derivatives of isosorbide having formula (I) wherein R′ and R″ represent hydrogen or a polymeric ether moiety (CH2—CHR1—O)x—H, where R1 represents hydrogen, or an alkyl or alkenyl moiety having 1 to 33 carbon atoms, which is saturated or unsaturated, branched or linear. This polymeric ether moiety can be a homopolymer or a copolymer, with x being the total degree of polymerization (DP). Preferred is a block copolymer composed of monomer A (DP=a), preferably ethylene oxide or propylene oxide, and monomer B (DP=b), preferably a saturated or unsaturated, branched or linear alkyl or alkenyl moiety having 1 to 33 carbon atoms, where x=a+b. x is a number from 0 to 50, with the proviso that R′ and R″ are not both hydrogen. The isosorbide derivatives are useful as components of detergent, cleanser, cosmetic and agricultural compositions. |
US08575369B2 |
Process for the production of alpha-tocotrienol and derivatives
The invention discloses novel processes for production, enrichment and/or isolation of alpha-tocotrienol from source material comprising at least one non-alpha-tocotrienol, such as natural extracts comprising mixed tocotrienols. |
US08575367B2 |
Ketal ester derivatives
The present disclosure relates to the preparation of acrylate, alkacrylate, allyl, and polycarbonate derivatives of hydroxy ketal esters, and uses thereof. |
US08575363B2 |
Amino-pyrrolidine-azetidine diamides as monoacylglycerol lipase inhibitors
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds, and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof, are represented by Formula (I) as follows: wherein Y, Z, and R1, and R2 are defined herein. |
US08575361B2 |
Tetrahydronaphthalene derivatives
This invention relates to novel tetrahydronaphthalene derivatives, and pharmaceutically acceptable salts thereof according to the following formulae, in one embodiment: as described herein. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a selective T-type calcium channel blocker. |
US08575359B2 |
Acid-sensitive linkers for drug delivery
The invention is in general directed to acid-sensitive linkers, and methods of use thereof, such as, for example, in drug delivery methods. |
US08575357B2 |
Substituted (thiazolyl-carbonyl)imidazolidinones and use thereof
The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals. |
US08575356B2 |
Heterocyclic alkanol derivatives
The present invention relates to novel heterocyclic alkanol derivatives, to processes for preparing these compounds, to compositions comprising these compounds and to their use as biologically active compounds, in particular for controlling harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators. |
US08575348B2 |
Quinolone inhibitors of lipoprotein-associated phospholipase A2
The present invention relates to new quinolone inhibitors of lipoprotein-associated phospholipase A2 activity, pharmaceutical compositions thereof, and methods of use thereof. |
US08575345B2 |
Molecular cobalt pentapyridine catalysts for generating hydrogen from water
A composition of matter suitable for the generation of hydrogen from water is described, the positively charged cation of the composition including the moiety of the general formula. [(PY5Me2)CoL]2+, where L can be H2O, OH−, a halide, alcohol, ether, amine, and the like. In embodiments of the invention, water, such as tap water or sea water can be subject to low electric potentials, with the result being, among other things, the generation of hydrogen. |
US08575338B2 |
Pyrimidine, pyridine and triazine derivatives as maxi-K channel openers
A compound of formula (A); wherein ring A is an aromatic ring or a heteroaromatic ring; R1 is independently halogen, cyano, etc., each of X1, X2 and X3 is CR2 or nitrogen, R2 is independently hydrogens, etc., n is 0, 1, 2, 3 or 4; -D-Y is —O—CH2COOH, etc, and G is a substituted amino, a substituted heterocyclic group, etc, or a pharmaceutical acceptable salt thereof, has activities of opening BK channels. |
US08575337B2 |
Oxazolidinone derivative having fused ring
The present invention provides a novel antimicrobial drug comprising an oxazolidinone derivative of the formula (I): or a pharmaceutically acceptable salt or solvate thereof. |
US08575335B2 |
Method of preparing nitrogen-doped graphene and nitrogen-doped graphene prepared thereby
The present invention relates to a method of preparing a nitrogen-doped graphene comprising preparing a Edge-Functionalized Graphene by binding a graphite with a organic material having amino groups and functional groups such as carboxy acid group through an electrophilic substitution reaction, and heat treating the resultant Edge-Functionalized Graphene, and a nitrogen-doped graphene prepared thereby. According to the present invention, by a more inexpensive and simpler method, a nitrogen-doped graphene can be prepared at higher purity and higher yield. The nitrogen-doped graphene obtained by the present invention has very excellent physical and electric properties, and particularly has a superior oxygen reduction capability, compared with the platinum catalyst used at cathode of a H2/O2 fuel cell so that it will replace the platinum to lower more the cost of a H2/O2 fuel cell or to increase its life and further to provide a new turning point for the commercialization of a H2/O2 fuel cell. |
US08575330B2 |
MicroRNA-based short hairpin RNA for gene knockdown of NR1 subunit of N-methyl-D-aspartate receptor and its application on pharmaceutics
The present invention relates to a microRNA-based short hairpin RNA for gene silencing the genetic expression of NR1 subunit of N-methyl-D-aspartate receptor comprises a single strand RNA fragment comprising a first fragment, a second fragment and a connecting fragment, wherein the first fragment and the second fragment are complementary to each other, and are spaced and connected by the connecting fragment, with the connecting fragment being randomly arranged nucleotides, with the first fragment having a Drosha recognized cleavage site, a silencing site and a Dicer recognized cleavage site, with the Drosha recognized cleavage site and the Dicer recognized cleavage site being spaced and connected by the silencing site, with the silencing site encoding homologous nucleotides corresponding to NR1 subunit of subcutaneous N-methyl-D-aspartate receptor. |
US08575323B2 |
Thermophilic and thermoacidophilic sugar transporter genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for transporting sugars across cell membranes using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius. |
US08575322B2 |
Polynucleotide and polypeptide sequence and methods thereof
The present disclosure relates to a field of recombinant DNA therapeutics. It involves the bio-informatics design, synthesis of artificial gene for human insulin precursor including leader peptide coding sequence, cloning in an expression vector and expression in an organism, preferably Pichia pastoris. The present disclosure also relates to methods of downstream processing for obtaining protein precursor molecules and subsequent conversion of precursor molecules to functional proteins. |
US08575321B2 |
Benzylbenzene derivatives and methods of use
Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition. |
US08575313B2 |
Process for extracting keratin
The present invention relates to a process for extracting keratin from poultry feather, and provides a quicker process thus allowing large-scale productions of the keratin production to be carried out in timely manner thus increasing the productivity and efficiency of such process. |
US08575312B2 |
Compositions and methods of use for MGD-CSF in disease treatment
Disclosed is a newly identified secreted molecule, identified herein as “monocyte, granulocyte, and dendritic cell colony stimulating factor” (MGD-CSF), the polypeptide sequence, and polynucleotides encoding the polypeptide sequence. Also provided is a procedure for producing the polypeptide by recombinant techniques employing, for example, vectors and host cells. Additionally, procedures are described to modify the disclosed novel molecules of the invention to prepare fusion molecules. Also disclosed are methods for using the polypeptides and active fragments thereof for treatment of a variety of diseases, including, for example, cancer, autoimmune and inflammatory diseases, infectious diseases, and recurrent pregnancy loss. |
US08575311B2 |
Collagen peptide conjugates and uses therefor
Described herein are conjugates of collagen peptides and metal binding agents and compositions resulting therefrom, useful in various tissue engineering and regeneration applications, in cell culture, cell adhesion, cosmetic surgery, construction of artificial skin substitutes, management of severe burns and burn surgery, reconstruction of bone and a wide variety of dental, orthopedic and surgical purposes, as drug delivery vehicles and in delivering populations of cells to a site of disease or injury. |
US08575307B2 |
Protein kinase C inhibitors for prevention of insulin resistance and type 2 diabetes
The present invention provides peptides and peptide analogs capable of inhibiting the activity of protein kinase C. The invention discloses use of such peptides and analogs for preparation of pharmaceutical compositions and methods for prevention, delay, suppression or treatment of type 2 diabetes using such compositions. |
US08575306B2 |
Target and method for inhibition of bacterial RNA polymerase
Target and method for inhibition of bacterial RNA polymerase disclosed are targets and methods for specific binding and inhibition of RNAP from bacterial species. |
US08575305B2 |
Cell penetrating peptides
The present invention discloses cell penetrating peptides and conjugates of a cell penetrating peptide and a cargo molecule. |
US08575303B2 |
Reagents for directed biomarker signal amplification
Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods. |
US08575302B2 |
Polylactide composition
A composition which comprises polylactide and has excellent heat stability, color and hydrolytic resistance. The composition comprises (i) polylactide, (ii) a metal catalyst and (iii) a hypophosphorous acid-based deactivator or a metaphosphoric acid-based deactivator. |
US08575301B2 |
Absorbable polymer formulations
A co-polyester which includes the reaction product of a polycondensation polyester and epsilon-caprolactone, wherein the polycondensation polyester comprises the reaction product of diglycolic acid and/or a derivative thereof and a diol. The co-polyester is injectable and absorbable into animal, such as human, tissue and can be used for facial cosmetic or reconstructive surgery of soft tissue. Another embodiment is directed to a method for preventing adhesion using a co-polyester comprising the reaction product of a polycondensation polyester and epsilon-caprolactone, wherein the polycondensation polyester comprises the reaction product of diglycolic acid and/or a derivative thereof and a diol, and the co-polyester comprises about 40 to 50% by weight of the polycondensation polyester based on the total weight of the co-polyester. |
US08575296B2 |
Polyester articles having simulated metallic or pearlescent appearance
A polyester article is made to appear lustrously metallic or pearlescent by the addition of polymethylpentene and non-metallic, non-pearlescent colorant; and optionally other functional additives. The colorant can be one or more pigments, one or more dyes, or combination thereof. A stretch blow molded plastic article, such as a bottle, using the polymethylpentene in the polyester can simulate the appearance of a metallic surface or a pearlescent luster even though non-metallic and non-pearlescent colorants are used. |
US08575293B2 |
Resin composition for optical material and optical material using the same
According to the present invention, a resin compound for optical material, comprising (a) an episulfide compound represented by a specific structural formula, (b) a xylylenedithiol compound and (c) a xylylenediisocyanate compound can be provided. In a preferable embodiment of the present invention, a resin compound for optical material having superb optical properties, a high density and a high thermal resistance can be provided. Also according to the present invention, an optical material obtained by curing the above-described resin compound can be provided. |
US08575290B2 |
Silicone resin composition, silicone resin sheet, optical semiconductor element device, and producing method of silicone resin sheet
A silicone resin composition contains a first organopolysiloxane having, in one molecule, both at least two ethylenically unsaturated hydrocarbon groups and at least two hydrosilyl groups; a second organopolysiloxane having, in one molecule, at least two hydrosilyl groups without containing an ethylenically unsaturated hydrocarbon group; a hydrosilylation catalyst; and a hydrosilylation inhibitor. |
US08575289B1 |
Elastomer product from epoxidized vegetable oil and gliadin
Disclosed is a bio-based and environmentally friendly elastomer product from renewable agricultural substrates. Specifically, glutamine and arginine residues of gliadin are used as synthons to produce novel elastomeric product from the reaction of the oxirane groups of epoxidized vegetable oils under neat reaction conditions with the primary amide functionalities of glutamine and arginine to give the corresponding amidohyroxy gliadinyl triglycerides. |
US08575288B2 |
Photocurable resin composition for forming overcoats RGB pixels black matrixes or spacers in color filter production, and color filters
A curable resin composition is provided which uses a fumarate copolymer which is excellent in thermal discoloration resistance as a binder component and is capable of forming details of a color filter. The curable resin composition of the present invention is a photocurable resin composition for forming a protective layer, RGB pixels, a black matrix or a spacer of a color filter, and contains as a binder component a fumarate copolymer having at least a molecular structure wherein a constituent unit represented by the following Formula 1 and a constituent unit having an acidic functional group(s) are linked, preferably further having a constituent unit with an ethylenically unsaturated bond: wherein, each of R1 and R2 is independently a branched C3-8 alkyl group which may be substituted, or a C4-8 cycloalkyl group which may be substituted. |
US08575286B2 |
Vinylidene fluoride and trifluoroethylene containing polymers
A polymer comprising recurring units derived from vinylidene fluoride (VDF) and trifluoroethylene (TrFE), such polymer comprising end groups of formula —CF2H and/or —CF2CH3 in an amount of at least 60 mmoles per kg of VDF recurring units [polymer (F)], a process for its manufacture and the use thereof as ferroelectric, piezoelectric, dielectric or pyroelectric material in electric/electronic devices. |
US08575283B1 |
Heterocyclic organic compounds as electron donors for polyolefin catalysts
Heterocyclic organic compounds are used as electron donors in conjunction with solid Ziegler-Natta type catalyst in processes in which polyolefins such as polypropylene are produced. The electron donors may be used in the preparation of solid catalyst system, thus serving as “internal electron donors”, or they may be employed during or prior to polymerization with the co-catalyst as “external electron donors”. |
US08575272B2 |
Polyolefinic compositions
A polymer composition comprising (percent by weight):a) 57%-74%, of a crystalline propylene polymer having an amount of isotactic pentads (mmmm), measured by 13C-MNR on the fraction insoluble in xylene at 25° C., higher than 97.5 molar % and a polydispersity index ranging from 5 to 10;b) 8 to 15%, of an elastomeric copolymer of ethylene and propylene, the copolymer having an amount of recurring units deriving from ethylene ranging from 30 to 50%, and being partially soluble in xylene at ambient temperature; the polymer fraction soluble in xylene at ambient temperature having an intrinsic viscosity value ranging from 2.5 to 3.5 dl/g; and c) 18-28%, of ethylene homopolymer having an intrinsic viscosity value ranging from 1.5 to 4 dl/g; said composition having a value of melt flow rate ranging from 35 to 60 g/10 min, and the amount of hexane extractables lower than 4.0 wt %. |
US08575267B2 |
Process for hydrolyzing polymers containing vinylcarboxamide units
A process for the hydrolysis of polymers comprising vinylcarboxamide units by heating polymers comprising vinylcarboxamide units in an aqueous medium in the presence of acids or bases, wherein an aqueous solution or dispersion of a polymer comprising vinylcarboxamide units and an aqueous solution or a base or acid are fed continuously to a tubular reactor at elevated pressure, from 0.05 to less than one equivalent of a base or acid being used per vinylcarboxamide equivalent and the mixture being passed through the tubular reactor at a temperature of >100° C. to 250° C., depressurized and cooled. |
US08575265B2 |
Polymerization method for acrylic latex without emulisifier
The present invention provides a polymerization method for acrylic latex without emulsifier, in which a reaction system is formed from 40˜60 wt % of pure water and 2˜9 wt % of carboxylic acid monomers with carbon-carbon double bond polymerizable functional groups (A), and 40˜50 wt % of methyl methacrylate or acrylate monomers (B), and 0.2˜2.0 wt % of inorganic alkaline solution is first used to adjust the pH value of the reaction system to within a pH range of 9.0˜13.0, then 0.2˜1.0 wt % of peroxide sulfates are used as initiators, and emulsification polymerization is carried out. At the end of the reaction, organic amine compounds are used to adjust the pH value of the obtained aqueous resin latex to within the pH range 7.0˜9.5. Particle diameters of the manufactured aqueous resin latex are approximately 100˜30 nm, uniformly distributed and have excellent outward appearance. Moreover, acid value is low at 3.5˜6.5 mgKOH/g, and Its specific gravity is approximately 1.07, slightly greater than that of water; storage stability is excellent, with good permeability that facilitates construction. Moreover, water resisting property as a dry film coating is good, tensile strength is excellent, and provides superior abrasion performance. |
US08575264B2 |
Method to establish viscosity as a function of shear rate for in-situ polymerized nanonylon via chain extension
Chain-extended nanonylon is made from the reaction of in-situ polymerized nanonylon and chain-extending agents. Knowing the viscosity/shear rate curve for a thermoplastic polymer to be replaced, such as nylon, the method of the present invention allows via adjustment of organoclay concentration and chain extension of the nylon polymer and other reaction factors to achieve a chain-extended, in-situ polymerized nanonylon to have a viscosity/shear rate curve that essentially matches the viscosity/shear rate curve for that neat nylon within a commercially operable shear rate. |
US08575261B2 |
Preparation of silica-containing EPDM rubber composition and use thereof for articles of manufacture including tires and engineered products
This invention relates to preparation of precipitated silica-containing EPDM based rubber compositions and their use as components of articles of manufacture such as, for example, tires and industrial products. Such preparation relies upon phase mixing of EPDM based rubber compositions which contain particulate reinforcement, such as for example precipitated silica, which may optionally include exfoliated clay reinforcement, to create an enhanced EPDM rubber composition. In one aspect, the invention relates to a pneumatic rubber tire with a visible outer sidewall rubber layer comprised of such rubber composition. |
US08575260B2 |
Polymer thick film encapsulant and enhanced stability PTC carbon system
The invention is directed to a polymer thick film encapsulant composition comprising thermoplastic fluoropolymer resin and acrylic resin dissolved in organic solvents. The deposited encapsulant composition is processed at a time and energy sufficient to remove all solvent and form an encapsulant. The invention is further directed to using the encapsulant composition to form an encapsulant in PTC heater circuitry and, in particular, in PTC heater circuitry in mirror heater and seat heater applications. |
US08575256B2 |
Dispersion of hybrid polyurethane with olefin-acrylic copolymerization
A product and processes comprising urethane polymer and at least one copolymer from a hydrophobic ethylenically unsaturated C4-C30 olefins copolymerized with polar monomers such as acrylates. One process optionally utilizes an acid source to modify/catalyze the reactivity of the polar monomer and/or radically activated repeat unit from the polar monomer to promote incorporation of the ethylenically unsaturated olefin. Other processes vary depending on which polymer if formed and/or dispersed first. The hybrid copolymer shows excellent adhesion to a variety of polymeric and/or polar substrates such as polyolefins, acrylate coatings, wood, etc. |
US08575253B2 |
Aramid particles containing peroxide radical intiator
An aramid particle containing a peroxide radical initiator wherein the particle contains 3-40 wt % peroxide radical initiator based on the weight of the aramid particle. Also, disclosed is a particle-elastomer composition having 100 parts by weight of at least one natural or synthetic elastomer, such as rubber; 0.1 to 20 parts by weight of a peroxide or 0.1 to 25 parts by weight of sulfur, an amount of a sulfur donor providing the equivalent of 0.1 to 25 parts by weight of sulfur, or a mixture of sulfur and a sulfur donor to an equivalent total of 0.1 to 25 parts by weight of sulfur; and 0.1 to 20 parts by weight of the aramid particle. |
US08575252B2 |
Controlled rheology formulations containing high melt strength polypropylene for extrusion coating
A process of extruding a blend of an irradiated first propylene polymer and a non-irradiated second propylene polymer, where the first propylene polymer comprises a non-phenolic stabilizer. The irradiation of the first propylene polymer extrudate is conducted in a reduced oxygen environment, and the irradiated first propylene polymer and the non-irradiated second propylene polymer are blended at a temperature below their respective melting points. The blend has a viscosity retention of 20 to 35%. |
US08575249B2 |
High heat-resistant polygermane compound with sulfur-containing organic group
There is provided a polygermane compound forming a film having a high refractive index and thermal stability, and containing a sulfur atom-containing organic group as a group bonded to a germanium atom. A polygermane compound comprising a sulfur atom-containing organic group as a group bonded to a germanium atom, in which the sulfur atom-containing organic group is a group of Formula [1]: -L-Z [1] where L is a single bond, a C1-6 alkylene group, or a C4-20 arylene group optionally substituted with a C1-6 alkyl group; and Z is a C1-20 sulfide group, a C1-14 cyclic sulfide group optionally substituted with a C1-6 alkyl group, a C2-20 alkyl group containing a sulfide bond, or a C5-20 aralkyl group containing a sulfide bond, with a proviso that when L is a single bond, Z is not a C1-20 sulfide group. |
US08575244B2 |
Solvents in the preparation of polyuretherane dispersions
The present invention relates to substituted N-(cyclo)alkylpyrrolidones as solvents for use in processes for preparing polyurethane dispersions. |
US08575242B2 |
Coating of organic and inorganic pigments with acrylic resins
Coating of organic and inorganic pigments with acrylic resins, comprising a chemical compound consisting of particles of solid organic and inorganic substances, both defined as pigments, in that they are substances which absorb a fraction of the light and reflect the complementary part thereof, coated with acrylic and, optionally, aldehyde and/or ketone resins. The latter are deposited on the surface of the pigment by means of a process which envisages melting of the resin, consequent wetting and coating of the entire surface of the pigment with the resin in the melted state, the consequent cooling and subsequent step of grinding by means of mechanical systems operating in temperature conditions lower than 20° C., by means of cryogenic processes or granulate by means of a wet method with a water jet cutting action and separation of the granulates by the water on a vibrating screen and then dried on a spiral elevator. The product resulting from this invention will be used as a semifinished product for the coloring and pigmentation of powder paints and plastics as a monochromatic coloring material and or will also be used, after dissolving in a solvent, or in water with basic pH, as a pigmented paste or directly in solvent or water based resins in the liquid paints industry. |
US08575240B2 |
Method for qualitatively and quantitatively identifying bulk goods
Identification and quantification of mass-produced goods in articles, a dye-containing polymer dispersion having been added to the mass-produced goods. The polymer dispersions contain particles which are coded by a mixture of dyes, and the polymer dispersion particles are quantitatively determined. |
US08575239B2 |
Curing composition and cured product prepared by using the same
The present invention relates to a curing composition comprising a polyarylate having epoxy group and a cyanate ester resin, and a cured product prepared by using the same. The curing composition according to the present invention is used to provide a cured product which is excellent in terms of heat resistance and toughness. |
US08575235B2 |
Removable hydrophobic composition, removable hydrophobic coating layer and fabrication method thereof
A removable hydrophobic composition, a removable hydrophobic coating layer and a fabrication method thereof are provided. The removable hydrophobic composition comprises 0.1-50 parts by weight of nano-particles having diameters smaller than 100 nm and of which surfaces are modified with silicon hydride compound, 0.1-5 parts by weight of an adhesion regulator or adhesion inhibitor, 100 parts by weight of a solvent, and 0.1-50 parts by weight of a polymer compound. |
US08575234B2 |
Ink composition, and method of forming pattern, color filter and method of preparing color filter using the same
An ink composition, and a method of forming a pattern, a color filter and a method of manufacturing the color filter using the same. The ink composition includes a binder resin, a multifunctional monomer having an ethylenic unsaturated double bond, a coloring agent, a polymerization initiator containing a certain positive ion and a solvent. Therefore, the composition has excellent coating property and chemical resistance and also an improved adhesion to a printing member, and thus the ink composition may be useful in forming a precise micropattern using a roll printing method, particularly a reversed printing method. |
US08575231B2 |
Antifouling composition
The present invention relates to the use of polyoxalates as binders for antifouling coating compositions and antifouling coating compositions comprising the polyoxalates. |
US08575230B2 |
Environment-friendly antifoulants for the prevention of biofouling
Environmentally-friendly alternatives to organometallic antifoulants that are efficacious at preventing biofouling by organisms such as the zebra mussel. Preferred antifoulant compositions utilize compounds having a Lipophilic-Amide-Spacer-ElectroNegative (“LASEN”) structural motif, such as capsaicin, and compounds having a TetraHydroCannibinoid (“THC”) structural motif. The antifoulant compositions are non-toxic, and effective. |
US08575227B2 |
Photocurable resin composition and optical component using the same
The present invention relates to a photocurable resin composition including an epoxy resin, an oxetane compound and a photopolymerization initiator, in which the epoxy resin includes the following ingredient (A), and the oxetane compound includes the following ingredient (B), and the ingredient (A) is contained in an amount of from 60 to 95% by weight and the ingredient (B) is contained in an amount of from 5 to 40% by weight relative to 100% by weight of a total resin amount in the resin composition: (A) an epoxy resin having at least two epoxy groups in one molecule thereof and being liquid at room temperature; and (B) an oxetane compound represented by the following general formula (I) in which n is an integer of from 1 to 6. |
US08575221B2 |
Derivatives of dimethylcurcumin
The invention relates to compounds of Formula I or Ia as disclosed herein: or pharmaceutically acceptable salts thereof or tautomers thereof. |
US08575217B2 |
Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders
The present invention is directed to methods for treating metabolic disorders with compounds that are conjugates. The conjugates of the present invention are comprised of salicylic acid, triflusal, diflusinal, salsalate, IMD-0354, ibuprofen, diclofenac, licofelone, or HTB, and one or more antioxidants. |
US08575214B2 |
MGlu 2/3 agonists
The present invention provides novel mGlu2/3 agonists of the formula wherein R1, R2, and R3 are as defined herein, for use in the treatment of neurological or psychiatric disorders. |
US08575211B2 |
Synergistic combination of analgesic compounds
The present invention relates to a pharmaceutical composition comprising as active substances: at least one compound of the following general formula (I): and at least one compound of the following general formula (V): especially for its use in the prevention or treatment of pain. |
US08575209B2 |
Modulators of ATP-binding cassette transporters
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention. |
US08575208B2 |
Inhibitors of serine proteases
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. |
US08575207B2 |
Method of activating regulatory T cells with alpha-2B adrenergic receptor agonists
Disclosed herein is a method of upregulating regulatory T-cells, and treating diseases that would benefit from such upregulation, by administering an alpha 2 receptor agonist. |
US08575205B2 |
Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infection. |
US08575202B2 |
Chelator stabilized cationic ammonium compounds and compositions comprising the same
Stabilized cationic ammonium compounds are described. The compounds are stabilized with pyridine-based chelators and/or heteroketo-based chelators that impede the generation of nitrogen comprising groups from the cationic ammonium compounds. |
US08575196B2 |
Oligomer-opioid agonist conjugates
The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer. |
US08575195B2 |
Treatment of hepatitis C virus related diseases using hydroxychloroquine or a combination of hydroxychloroquine and an anti-viral agent
Methods of treating a hepatitis C virus (HCV) related disease, such as HCV infections in subjects non-responsive to anti-HCV therapy, are described herein, comprising administering to the subject a therapeutically effective amount of hydroxychloroquine. An antiviral agent may be co-administered with the hydroxychloroquine. Methods utilizing synergistic combinations of hydroxychloroquine and an antiviral agent are disclosed. Further disclosed are compositions comprising hydroxychloroquine and an antiviral agent, as well as hydroxychloroquine and uses thereof for the treatment of a hepatitis C virus (HCV) related disease. |
US08575191B2 |
Methods for treatment of non-small cell lung cancer
The present invention provides methods of treating non-small cell lung cancer by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound in combination with a therapeutically effective amount of an epidermal growth factor tyrosine kinase inhibitor. |
US08575190B2 |
Method of preventing or ameliorating psoriasis using pyrroloquinoline quinone compounds
The present invention provides a method for preventing or ameliorating skin psoriasis by applying as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom). |
US08575189B2 |
Tacrolimus preparation for external applications
The present invention provides tacrolimus containing ointment having low dermal irritation and excellent stability. It was found that an ointment comprising triacetin as a solubilizer for tacrolimus may sufficiently solubilize tacrolimus, has low dermal irritation and excellent stability. Preferably, the ointment of the present invention is an o/o type (oil-in-oil type) ointment in which tacrolimus-solubilized triacetin droplets are dispersed in an ointment base, preferably a mixture of beeswax and petrolatum. |
US08575188B2 |
Camptothecin derivatives
Various 14-nitro, 14-amino, and 14-substituted amino camptothecin derivatives are useful in the treatment of cancer and other hyperproliferative diseases. 14-Nitro camptothecin derivatives are conveniently prepared by reacting a camptothecin derivative with fuming nitric acid, optionally employing acetic anhydride as a solvent. |
US08575182B2 |
6, 9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions
Certain 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts of the general formula are provided wherein R6 and R9 are as defined in the specification. These 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are useful in compositions for treating mammalian cells, and especially human skin cells, in order to ameliorate the adverse effects of aging, treat skin disease states, treat immunological responses resulting from or associated with inflammation, and the like. |
US08575176B2 |
Heteroaromatic pyrazinoylguanidine sodium channel blockers
Polyaromatic sodium channel blockers represented by the formula: are provided where the structural variables are defined herein. The invention also includes a variety of compositions, combinations and methods of treatment using these inventive sodium channel blockers. |
US08575170B2 |
Flurbiprofen analogs and methods of use in treating cancer
Flurbiprofen analog compounds having an amino acid derivatized at the flurbiprofen alkanoic acid carboxyl group and terminating at an ester or amide group are effective in inhibiting cancer cells in vitro and inhibiting the growth of cancers in viva. The compounds and pharmaceutical compositions containing them are particularly useful for the treatment of lung, pancreatic and head and neck cancers. |
US08575167B2 |
Spiro compounds having stearoyl-CoA desaturase action
The present invention aims to provide a novel SCD inhibitor.The present invention relate to SCD inhibitor comprising A compound represented by the formula (I) wherein R is an optionally substituted cyclic group or an optionally substituted carbamoyl group, provided that R is not an optionally substituted 7-pyrido[2,3-d]pyrimidyl group; ring A is an optionally further substituted pyridazine ring; R1, R2, R3, R4, R11, R12, R13 and R14 are each independently a hydrogen atom or a substituent, or R1 and R11 in combination, R2 and R12 in combination, R3 and R13 in combination, or R4 and R14 in combination optionally form an oxo group, or R2 and R4 in combination optionally form a bond or an alkylene cross-linkage; m and n are each independently an integer of 0 to 2; ring B is an optionally substituted ring, provided that the two atoms constituting ring B, which are adjacent to the spiro carbon atom, are not oxygen atoms at the same time, or a salt thereof, or a prodrug thereof. |
US08575165B2 |
Methods for treating inflammatory disorders using 2,4-pyrimidinediamine compounds
Methods for treating an inflammatory disorder and for inhibiting the production of IL-23 using 2,4-pyrimidinediamine compounds represented by formula (I): |
US08575156B2 |
Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
Disclosed are compounds represented by Formula (I): or pharmaceutically acceptable salts, enantiomers or diastereomers thereof. Also disclosed are pharmaceutical compositions comprising the compounds of Formula (I) or pharmaceutically acceptable salts, enantiomers or diastereomers thereof and methods of inhibiting 11β-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer or diastereomer thereof. Values for the variables in Formula (I) are defined herein. |
US08575155B2 |
Composition and method to modify sperm function and increase male gender ratio in mammals
A composition and method is provided for modifying sperm fertility in mammals for the purpose of biasing the gender in favor of male offspring. The composition includes an amount of a class of compounds of phenoxazine or phenothiazine, having the structure (FIG. 1) and ionic derivatives thereof, wherein R1 is H, a lower alkyl group or N(R3)2, R2 is N, S, O, and R3 is H or a lower alkyl group. A second component of the composition is an amount of a hexose sugar or the phosphorylated hexose esters of such. When mixed with living sperm prior to or at the time of insemination, the composition results in modified rates of conception and an alteration of the birth sex ratio. |
US08575154B2 |
Heterocyclic compound and use thereof
Provided is a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof, which has an AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor potentiating action. The compound of the present invention is useful as a prophylactic or therapeutic drug for depression, schizophrenia, Alzheimer's disease or attention deficit hyperactivity disorder (ADHD) and the like. |
US08575152B2 |
Non-steroidal compounds useful as glucocorticoid receptor modulators
This invention relates to novel amino acid derivatives of formula (I) wherein the R groups have the following meanings: —R1 is —H or —(1-4C)alkyl; —R2 is —C(O)R15 or —S(O)2R15; —R3 is —H, —(1-4C)alkyl or —OR16; —R4 is —H, —(1-4C)alkyl or —OR16; —R6 is —H or —C(R16)NOR16; —R7 is —H, -halogen, -cyano; —(1-6C)alkyl, —(2-6C)alkenyl or —(2-6C)alkynyl, all optionally substituted with -amino, -hydroxyl or -halogen; —R8 is —H, -cyano, -halogen, -nitro; —(1-6C)alkyl, —(2-6C)alkenyl, —(2-6C)alkynyl or —O(1-6C)alkyl, all optionally substituted with -amino, -hydroxyl or -halogen; -(hetero)aryl, optionally substituted with -cyano, -halogen, —(1-4C)alkyl, —(1-4C)alkoxy, —(1-4C)alkoxy(1-4C)alkyl or -(hetero)aryl; —C(R16)NOR16; —C(O)N(R17)2; —C(O)R18, —C(O)OR19, —NHC(O)R20, or —NHS(O)2R21; —R9 is —H, -halogen, -cyano, or —(1-4C)alkyl, optionally substituted with -halogen; —R10 is —H or —(1-4C)alkyl; —R11 is —H; —R12 is —H, -cyano or —(1-4C)alkyl; —R13 is —H, —(1-4C)alkyl, -halogen or -formyl; —R14 is —H, -halogen, -cyano, —(1-4C)alkyl or -(hetero)aryl; or a pharmaceutically acceptable salt thereof. The compounds of this invention are highly specific for the glucocorticoid receptor and may be used for treating inflammatory diseases. |
US08575151B1 |
Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
Drug substances comprising a pharmaceutically acceptable organic acid addition salt of amine containing pharmaceutically active compounds useful for the treatment of a therapeutic ailment administration and exhibiting prophylactic properties when employed in non-therapeutic administration. |
US08575145B2 |
Triazolopyridine compounds as PIM kinase inhibitors
Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases. |
US08575141B2 |
Steroid-derived cyclopamine analogs and methods for using the same in the prevention or treatment of cancer
The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for synthesizing the analogs of the present invention from a steroid is also provided. |
US08575140B2 |
Treatment of congestion using steroids and adrenergics
A decongestant composition is provided comprising: (a) a safe and effective amount of an adrenergic compound; (b) a safe and effective amount of a steroid; and (c) a pharmaceutically-acceptable carrier. Methods of treating congestion in a human or animal subject are also provided comprising administering to the subject a composition comprising: (a) an adrenergic compound; and (b) a steroid; where the daily dose of the adrenergic compound administered to the subject is from about 1 μg to about 800 μg, and the daily dose of the steroid administered to the subject is from about 1 μg to about 400 μg. |
US08575137B2 |
Composition for inhalation
The invention relates to a formulation comprising formoterol and budesonide for use in the treatment of respiratory diseases. The composition further contains HFA 227, PVP and PEG, preferably PVP K25 and PEG 1000. |
US08575134B2 |
Aminocarboxylic acid derivative and medicinal use thereof
The present invention relates to a compound represented by the formula (I), a salt thereof, an N-oxide form thereof, a solvate thereof, or a prodrug thereof, and a medicament containing the same. The compound represented by the formula (I) has an ability to bind to an S1P receptor (particularly, EDG-1, EDG-6, and/or EDG-8) and is useful for preventing and/or treating for rejection to transplantation, graft-versus-host disease, autoimmune diseases, allergic diseases, neurodegenerating diseases, and the like. wherein all symbols are described in the specification. |
US08575130B2 |
Mixture of hyaluronic acid for treating and preventing inflammatory bowel disease
The present invention is related to a hyaluronic acid formulation including a mixture of hyaluronic acids having different weight-average molecular weight and different rheological, tissue scaffold, insulation and degradation properties in aqueous solution. The resulting formulation demonstrated an optimal balance between adhesion, tissue scaffold, insulation and treating time on the treatment and prevention of IBD (inflammatory bowel disease) such as ulcerative colitis and Crohn's disease. Thus, the formulation of the present invention exhibits a quick and lasting effect on the treatment and prevention of duodenal or peptic ulcer and bleeding which is very good thing indeed. |
US08575119B2 |
2′-chloroacetylenyl substituted nucleoside derivatives
The present invention relates to 2′-chloroacetylenyl-substituted nucleoside derivatives of the general formula (I): As well as pharmaceutical compositions comprising such compounds and methods to treat or prevent an HIV infection, HBV infection, HCV infection or abnormal cellular proliferation, comprising administering said compounds or compositions. In addition, the present invention includes processes for the preparation of such compounds, and the related β-D and β-L-nucleoside derivatives. |
US08575109B2 |
Recombinant pokeweed antiviral proteins, compositions and methods related thereto
The present invention provides novel, modified pokeweed antiviral proteins, nucleic acids that encode the proteins, conjugates that incorporate the proteins, and methods to make and use the proteins. The present invention also provides methods to administer the conjugates to animals, for the purpose of directing toxin to particular cells. |
US08575106B2 |
Cosmetic uses of modified stressed yeast extracts and related compositions
Cosmetic compositions comprising a metal-complexed peptide fraction of stressed yeast extracts and/or a calcium influx inhibitor are disclosed, as well as methods of using such compositions to impart exfoliating, anti-aging, anti-lipid, anti-inflammatory, and/or lightening benefits to the skin; and/or lightening benefits to the hair. These compositions are believed to have modulatory activity against at least one biochemical pathway implicated in skin aging, inflammation, lipid synthesis, and melanin production. |
US08575103B2 |
Peptides and methods for inhibiting G alpha protein signaling
Permeable Switch Region I and II peptides in the range of 9 to 25 amino acid residues in length are provided for specifically inhibiting signaling through Gα subunits. In addition, compositions and methods for inhibiting platelet aggregation and α11bβ3 integrin activation using the Switch Region I and II peptides are provided. |
US08575099B2 |
Agent for treating polyglutamine aggregation-caused disease or suppressing onset thereof
The present invention discloses an agent for treating a polyglutamine aggregation-caused disease or suppressing its onset, which comprises, as an active ingredient, (1) (i) HGF protein, (ii) a partial peptide of HGF protein that is substantially equivalent in activity to HGF protein, or a salt of either of them, or (2) DNA containing (i) DNA encoding HGF protein, (ii) DNA encoding a partial peptide of HGF protein that is substantially equivalent in activity to HGF protein or (iii) DNA which encodes a protein or a peptide that is substantially equivalent in activity to HGF protein and hybridizes with DNA comprising a complementary base sequence of either of the above-mentioned DNAs under a stringent condition. |
US08575098B2 |
Biopolymer, implant comprising it and uses thereof
The present invention relates to a biopolymer, bioactive and totally biocompatible, very fluid at ambient temperature, capable of gelling in a sudden manner at 37° C., forming a solid implant, structurally integral and continuous having high mechanical properties. The biopolymer comprises at least a bioactive domain capable of directing in a precise manner the formation of a solid or semisolid implant. Furthermore the invention relates to any of the nucleic acids encoding the amino acid sequence of the biopolymer, implants, pharmaceutically acceptable vehicles, uses thereof, and a method of synthesis thereof. |
US08575095B2 |
Active cores of peptide triazole HIV-1 entry inhibitors
The invention provides a peptide triazole conjugate and derivatives thereof, and methods of its use. Further provided are an antibody to the peptide triazole conjugate, and a method of identifying an HIV-1 entry inhibitor candidate. |
US08575082B2 |
Additive to improve flow, reduce power consumption and pressure drop in heavy oil pipelines
A drag reducing additive for heavy oil, such as crude oil, includes a polymeric alkyl-substituted phenol formaldehyde resin and a solvent having at least one of an ester (e.g. ethyl acetate), an aldehyde (e.g. butyraldehyde), and an aromatic hydrocarbon (e.g. toluene, xylene, and the like), or mixtures thereof. When used together with a diluent (e.g. condensate, naphtha, or the like), the additive may reduce viscosity of the combined oil, diluent, and additive by at least 20%, increase throughput by at least 6%, reduce power consumption by at least 3%, reduce the diluent proportion by at least 3%, or some combination of these effects, as compared with an otherwise identical heavy oil without the additive. |
US08575079B2 |
Lube oil compositions
A lube oil composition is provided. The lube oil composition includes a base oil and a carbon nanocapsule grafting with an alkyl group dispersed in the base oil, wherein the carbon nanocapsule is hollow or filled with metal, metal alloy, metal oxide, metal carbide, metal sulfide, metal nitride or metal boride. |
US08575077B2 |
Environmental subsea control hydraulic fluid compositions
An aqueous hydraulic fluid composition comprising (i) a salt of formic acid, and (ii) one or more lubricants such as a monovalent metal salt, ammonium, or amine salt of a dicarboxylic acid, is described in which the aqueous hydraulic fluid composition demonstrates increased thermal stability when exposed to elevated temperatures for a prolonged period of time while being able to tolerate the presence of 10% v/v synthetic seawater. The aqueous hydraulic fluid composition contains less than about 20% by weight (preferably none or substantially none) of an oil selected from the group consisting of mineral oils, synthetic hydrocarbon oils, and mixtures thereof. The hydraulic fluid preferably contains no glycols in some embodiments. The pH of the hydraulic fluid is preferably from 8 to 10 and is maintained by a buffer which preferably comprises borax in some embodiments. |
US08575075B2 |
Oil-field viscosity breaker method utilizing a peracid
Aqueous well treatment fluid compositions are disclosed comprising an aqueous fluid containing polymer or copolymer for modifying fluid viscosity of the aqueous fluid and, in addition, an agent for effecting a controlled reduction in the aqueous fluid viscosity in a subterranean environment. The viscosity-reducing agent comprises a dilute concentration of peracetic acid. A method of using such compositions in oil- and gas-field treatment operations is also disclosed. |
US08575072B2 |
Fluid loss additives and methods of making and using same
A non-aqueous wellbore servicing fluid comprising a fluid loss additive wherein the fluid loss additive comprises the reaction product of (i) a functional polymer and (ii) an oligomerized fatty acid. A method of conducting an oil-field operation comprising placing a non-aqueous wellbore servicing fluid downhole wherein the non-aqueous wellbore servicing fluid comprises a fluid loss additive comprising the reaction product of (i) a functional polymer and (ii) an oligomerized fatty acid. |
US08575071B2 |
Reducing adapter dimer formation
Provided herein is a method of reducing adapter dimer formation comprising contacting a sample comprising target nucleic acid sequences with 5′ and 3′ adapters in the presence of one or more hairpin oligonucleotides. Also provided is a method of preparing a library of nucleic acid sequences comprising contacting first adapter oligonucleotides with a sample comprising target nucleic acid sequences under conditions to form first ligation products, contacting the sample with one or more hairpin oligonucleotides that binds to the first adapter oligonucleotides, and contacting the sample with second adapter oligonucleotides under conditions to bind to the first ligation products and form second ligation products, wherein the second ligation products form the library of nucleic acid sequences. |
US08575063B2 |
Nickel-based reforming catalysts
The present invention relates unique pore structures in nickel supported on alumina with the negligible formation of macropores. Incorporation of additional elements stabilizes the pore structure of the nickel supported on alumina. Additional element(s) were then further added into the nickel-supported materials. These additional element(s) further stabilize the pore structures under heating conditions. The improvements of pore structure stability under heating conditions and negligible presence of macropores limit the sintering of nickel metal to a mechanism of impeded diffusion. The negligible presence of macropores also limits the deposition of alkali metal hydroxide(s)/carbonate(s) on the outer shell of the catalyst pellet in the molten carbonate fuel cells. Both the negligible presence of macropores and improvement in pore structure stability allow for prolonging the catalyst life of these nickel supported on alumina catalysts of the present invention for reforming hydrocarbons. |
US08575062B2 |
Hydroconversion multi-metallic catalyst and method for making thereof
In a process for forming a bulk hydroprocessing catalyst by sulfiding a catalyst precursor in a co-precipitation reaction, up to 60% of the metal precursor feeds do not react to form catalyst precursor and stay in the supernatant. In one embodiment, at least a precipitant is added to the product mixture at a molar ratio of precipitant to metal residuals in the supernatant ranging from 1.5:1 to 20:1 to precipitate at least 50 mole % of metal ions in the residuals forming additional catalyst precursor. The remaining metal residuals can be recovered via any of chemical precipitation, ion exchange, electro-coagulation, and combinations thereof to generate an effluent stream containing less than 50 mole % of at least one of the metal residuals. In one embodiment, at least one of the metal residuals is recovered and recycled for use as a metal precursor feed in the co-precipitation reaction. |
US08575061B2 |
Hydroconversion multi-metallic catalyst and method for making thereof
In a process for forming a bulk hydroprocessing catalyst by sulfiding a catalyst precursor made in a co-precipitation reaction, up to 60% of metal ions in at least one of the metal precursor feeds do not react to form catalyst precursor and end up in the supernatant as metal residuals. In the present disclosure, the metals can be recovered via ion-exchange, wherein an exchange resin is provided for a portion of the metal ions in the supernatant to be exchanged and bound onto the resin. The previously resin-bound metals can be subsequently recovered, or the effluent stream for the exchange resin column can also be recovered, forming at least a metal precursor feed which can be used in the co-precipitation reaction. |
US08575060B2 |
Method of fabricating fuel reforming catalyst for SOFC power generating system
A fuel reforming catalyst is fabricated. The catalyst is used in solid oxide fuel cell. By using the catalyst, the hydrogen generation is enhanced with a great reforming ratio. In addition, the catalyst is coking-resistant and will not be broken into powder after a long time of use. |
US08575058B2 |
Activated carbon catalyst
An activated carbon catalyst is described which is sufficiently active in the presence of catalytic poisons in crude gas to convert nitrogen oxides to nitrogen in the presence of ammonia. |
US08575057B2 |
UV curable catalyst compositions
UV curable compositions and methods for depositing one or more metal or metal alloy films on substrates are disclosed. The UV curable compositions contain a catalyst, one or more carrier particles, one or more UV curing agents, and one or more water-soluble or water-dispersible organic compounds. Metal or metal alloys may be deposited on the substrates by electroless or electrolytic deposition. |
US08575050B2 |
Glass composition, glass substrate for flat panel display using the same, flat panel display, and method for producing glass substrate for flat panel display
Provided is a glass composition suitable for a glass substrate for a flat panel display such as a liquid crystal display. This glass composition has high thermal stability, and is substantially free of BaO but has a low devitrification temperature. It is suitable for the production of a glass substrate by a downdraw process. This glass composition contains, in terms of mass %; 54 to 62% of SiO2; 4 to 11% of B2O3; 15 to 20% of Al2O3; 2 to 5% of MgO; 0 to 7% of CaO; 0 to 13.5% of SrO; 0 to 1% of K2O; 0 to 1% of SnO2; and 0 to 0.2% of Fe2O3, and is substantially free of BaO. In this glass composition, the total content of alkaline earth metal oxides (MgO+CaO+SrO) is 10 to 18.5 mass %. The devitrification temperature of the glass composition is 1200° C. or lower. |
US08575048B2 |
Optical glass, precision press-molding preform, optical element and process for producing the same
[Problems to be Solved]To provide a high-refractivity low-dispersion optical glass that enables the stable production of high-quality optical elements.[Means to Solve the Problems]An optical glass comprising, as essential components, 20 to 50% of B3+, 5 to 35% of La3+, 1 to 30% of Nb5+, 0.5 to 15% of Ta5+, and 11 to 40% of Zn2+, the total content of B3+ and Si4+ being 20 to 50%, the total content of La3+, Gd3+ and Y3+ being 5 to 35%, the cationic ratio of ((B3++Si4+)/(La3++Gd3++Y3+)) being from 1 to 5, the total content of Ti4+, Nb5+, Ta5+ and W6+ being 10 to 35%, the cationic ratio of ((Nb5++Ta5+)/(Ti4++Nb5++Ta5++W6+)) being from 0.7 to 1, the cationic ratio of ((B3++Si4+)/(Ti4++Nb5++Ta5++W6+)) being from 0.5 to 4, the cationic ratio of ((La3++Gd3++Y3+)/(Ti4++Nb5++Ta5++W6+)) being from 0.2 to 3, the cationic ratio of Zn2+/Zn2++Mg2++Ca2++Sr2++Ba2+) being from 0.8 to 1, the optical glass having a refractive index nd of 1.89 or more and an Abbe's number νd of 27 to 37. |
US08575040B2 |
Low temperature process for polysilazane oxidation/densification
Semiconductor devices, structures and systems that utilize a polysilazane-based silicon oxide layer or fill, and methods of making the oxide layer are disclosed. In one embodiment, a polysilazane solution is deposited on a substrate and processed with ozone in a wet oxidation at low temperature to chemically modify the polysilazane material to a silicon oxide layer. |
US08575039B2 |
Surface treating method and film depositing method
A surface treating method for treating a surface of a substrate inside a process chamber includes the steps of generating an atmosphere containing no moisture in the process chamber, heating the substrate inside the atmosphere containing no moisture in the process chamber; and causing a reaction between the substrate and an adhesion accelerating agent by feeding the adhesion accelerating agent gas into the process chamber. |
US08575032B2 |
Methods of forming a pattern on a substrate
A method of forming a pattern on a substrate includes forming a repeating pattern of four first lines elevationally over an underlying substrate. A repeating pattern of four second lines is formed elevationally over and crossing the repeating pattern of four first lines. First alternating of the four second lines are removed from being received over the first lines. After the first alternating of the four second lines have been removed, elevationally exposed portions of alternating of the four first lines are removed to the underlying substrate using a remaining second alternating of the four second lines as a mask. Additional embodiments are disclosed and contemplated. |
US08575028B2 |
Method and apparatus for filling interconnect structures
Methods, apparatus, and systems for depositing copper and other metals are provided. In some implementations, a wafer substrate is provided to an apparatus. The wafer substrate has a surface with field regions and a feature. A copper layer is plated onto the surface of the wafer substrate. The copper layer is annealed to redistribute copper from regions of the wafer substrate to the feature. Implementations of the disclosed methods, apparatus, and systems allow for void-free bottom-up fill of features in a wafer substrate. |
US08575026B2 |
Method of protecting sidewall surfaces of a semiconductor substrate
One or more embodiments may include a method of making a semiconductor structure, comprising: forming a first opening partially through a semiconductor substrate; forming a first dielectric layer over a sidewall surface of the first opening; and forming a second opening partially through a semiconductor substrate, the second opening being below the first opening. |
US08575022B2 |
Top corner rounding of damascene wire for insulator crack suppression
A structure and method for fabricating the structure that provides a metal wire having a first height at an upper surface. An insulating material surrounding said metal wire is etched to a second height below said first height of said upper surface. The metal wire from said upper surface, after etching said insulating material, is planarized to remove sufficient material from a lateral edge portion of said metal wire such that a height of said lateral edge portion is equivalent to said second height of said insulating material surrounding said metal wire. |
US08575012B2 |
Semiconductor device production method and semiconductor device
A semiconductor device production method includes: forming an insulating film on a semiconductor substrate, forming a concave portion in the insulating film, forming a gate insulating film at bottom of the concave portion, the bottom being on the semiconductor substrate; covering an inner wall surface of the concave portion and a top face of the insulating film with a first gate electrode film that is made of an electrically conductive material containing a first metal; covering the first gate electrode film with a covering film of a material having a second melting point higher than a first melting point of the electrically conductive material, leaving part of the side face of the concave portion uncovered; and performing heat treatment following the covering film formation to allow the first gate electrode film to reflow. |
US08575009B2 |
Two-step hydrogen annealing process for creating uniform non-planar semiconductor devices at aggressive pitch
A two-step hydrogen anneal process has been developed for use in fabricating semiconductor nanowires for use in non-planar semiconductor devices. In the first part of the two-step hydrogen anneal process, which occurs prior to suspending a semiconductor nanowire, the initial roughness of at least the sidewalls of the semiconductor nanowire is reduced, while having at least the bottommost surface of the nanowire pinned to an uppermost surface of a substrate. After performing the first hydrogen anneal, the semiconductor nanowire is suspended and then a second hydrogen anneal is performed which further reduces the roughness of all exposed surfaces of the semiconductor nanowire and reshapes the semiconductor nanowire. By breaking the anneal into two steps, smaller semiconductor nanowires at a tight pitch survive the process and yield. |
US08575005B2 |
Method of manufacturing an electronic device having a plastic substrate and corresponding carrier
A method of manufacturing an electronic device on a plastic substrate includes: providing a carrier as a rigid support for the electronic device; providing a metallic layer on the carrier; forming the plastic substrate on the metallic layer, the metallic layer guaranteeing a temporary bonding of the plastic substrate to the carrier; forming the electronic device on the plastic substrate; and releasing the carrier from the plastic substrate. Releasing the carrier comprises immersing the electronic device bonded to the carrier in a oxygenated water solution that breaks the bonds between the plastic substrate and the metallic layer. |
US08575004B2 |
Lift-off structure for substrate of a photoelectric device and the method thereof
The present invention related to a lift-off structure adapted to a substrate having a photoelectric device, the structure comprising: a buffer layer, forming on the substrate; an upper sacrificial layer, forming on the buffer layer; an etch stop layer, forming on the upper sacrificial layer, and the photoelectric device structure forming on the etch stop layer. |
US08574996B2 |
Method of manufacturing semiconductor device
A method of manufacturing a semiconductor device comprises: forming a processing target; forming a first supporter on the processing target; forming a first mask so as to contact one side surface of the first mask with a side surface of the first supporter; patterning the processing target using, as masks, the first mask and the first supporter; forming a second supporter so as to be contacted with a side surface of the processing target exposed in first processing step and the other side surface of the first mask; removing the first supporter; and patterning the processing target using, as masks, the first mask and the second supporter. |
US08574994B1 |
HBT with emitter electrode having planar side walls
A heterojunction bipolar transistor is formed with an emitter electrode that comprises an emitter epitaxy underlying an emitter metal cap and that has horizontal dimensions that are substantially equal to the emitter metal cap. |
US08574993B2 |
Semiconductor device and method of manufacturing the same
According to one embodiment, a method of manufacturing a MOS semiconductor device. In the method, a gate electrode is formed on a gate insulating film provided on a channel region which is a part of an Si layer and which is interposed between a source/drain region, and a film mainly includes of Ge is made to grow on the source/drain region. Then, and the film mainly includes of Ge is made to react with a metal, forming an intermetallic compound film having a depthwise junction position identical to a growth interface of the film mainly includes of Ge. |
US08574992B2 |
Contact architecture for 3D memory array
A vertical interconnect architecture for a three-dimensional (3D) memory device suitable for low cost, high yield manufacturing is described. Conductive lines (e.g. word lines) for the 3D memory array, and contact pads for vertical connectors used for couple the array to decoding circuitry and the like, are formed as parts of the same patterned level of material. The same material layer can be used to form the contact pads and the conductive access lines by an etch process using a single mask. By forming the contact pads concurrently with the conductive lines, the patterned material of the contact pads can protect underlying circuit elements which could otherwise be damaged during patterning of the conductive lines. |
US08574989B2 |
Semiconductor structure having a polysilicon structure and method of forming same
The present application discloses a method of forming a semiconductor structure. In at least one embodiment, the method includes forming a polysilicon layer over a substrate. A mask layer is formed over the polysilicon layer. The mask layer is patterned to form a patterned mask layer. A polysilicon structure is formed by etching the polysilicon layer using the patterned mask layer as a mask. The polysilicon structure has an upper surface and a lower surface, and the etching of the polysilicon layer is arranged to cause a width of the upper surface of the polysilicon structure greater than that of the lower surface of the polysilicon structure. |
US08574987B1 |
Integrating formation of a replacement gate transistor and a non-volatile memory cell using an interlayer dielectric
A first dielectric layer is formed over a semiconductor layer in an NVM region and a logic region. A charge storage layer is formed over the first dielectric layer in the NVM and logic regions. The charge storage layer is patterned to form a dummy gate in the logic region and a charge storage structure in the NVM region. A second dielectric layer is formed over the semiconductor layer in the NVM and logic regions which surrounds the charge storage structure and the dummy gate. The dummy gate is replaced with a logic gate. The second dielectric layer is removed from the NVM region while protecting the second dielectric layer in the logic region. A third dielectric layer is formed over the charge storage structure, and a control gate layer is formed over the third dielectric layer. |
US08574986B2 |
Method for fabricating nonvolatile memory device
A method for fabricating a nonvolatile memory device includes forming a substrate structure having a tunnel dielectric layer and a floating-gate conductive layer formed over an active region defined by a first isolation layer forming a first inter-gate dielectric layer and a first control-gate conductive layer over the substrate structure, forming a trench by etching the first control-gate conductive layer, the first inter-gate dielectric layer, the floating-gate conductive layer, the tunnel dielectric layer, and the active region to a given depth, forming a second isolation layer to fill the trench; and forming a second control-gate conductive layer over the resultant structure having the second isolation layer formed therein. |
US08574980B2 |
Method of forming fully silicided NMOS and PMOS semiconductor devices having independent polysilicon gate thicknesses, and related device
A method of forming fully silicided NMOS and PMOS semiconductor devices having independent polysilicon gate thicknesses, and related device. At least some of the illustrative embodiments are methods comprising forming an N-type gate over a semiconductor substrate (the N-type gate having a first thickness), forming a P-type gate over the semiconductor substrate (the P-type gate having a second thickness different than the first thickness), and performing a simultaneous silicidation of the N-type gate and the P-type gate. |
US08574975B2 |
Semiconductor devices having e-fuse structures and methods of fabricating the same
A semiconductor device includes: an e-fuse gate, a floating pattern between the e-fuse gate and an e-fuse active portion, a blocking dielectric pattern between the floating pattern and the e-fuse gate, and an e-fuse dielectric layer between the floating pattern and the e-fuse active portion. The floating pattern includes a first portion between the e-fuse gate and the e-fuse active portion and a pair of second portions extended upward along both sidewalls of the e-fuse gate from both edges of the first portion. |
US08574974B2 |
Method of manufacturing a semiconductor device
Forming a photoresist on a region other than a region on a trench gate electrode for a mask, a third gate insulating film on the trench gate electrode is etched and removed. After that, a non-doped polycrystalline silicon layer is formed on second and third gate insulating films and also on the trench gate electrode, and, N-type and P-type high concentration impurities are introduced by an ion implantation with the use of separate masks on the polycrystalline silicon layer of NMOS transistors and PMOS transistors with a low breakdown voltage and a high breakdown voltage. Then, a second gate electrode is formed by anisotropic etching. With the steps as described above, a first gate electrode inside the trench and the second gate electrode to be used in the lateral MOS transistor are laminated, to thereby reduce fluctuations due to the etching. |
US08574973B1 |
Method of fabricating a lateral double-diffused MOSFET (LDMOS) transistor and a conventional CMOS transistor
An integrated circuit structure having an LDMOS transistor and a CMOS transistor includes a p-type substrate having a surface, an n-well implanted in the substrate, the first n-well providing a CMOS n-well, a CMOS transistor including a CMOS source with a first p+ region implanted in the n-well, a CMOS drain with a second p+ region implanted in the n-well, and a CMOS gate between the first p+ region and the second p+ region, and an LDMOS transistor including an LDMOS source with an LDMOS source including a p-body implanted in the n-well, a third p+ region implanted in the p-body, and a first n+ region implanted in the p-body, an LDMOS drain including an n-doped shallow drain implanted in the n-well, and a second n+ region implanted in the n-doped shallow drain, and an LDMOS gate between the third p+ region and the second n+ region. |
US08574972B2 |
Method for fabricating semiconductor device and plasma doping apparatus
After a fin-semiconductor region (13) is formed on a substrate (11), impurity-containing gas and oxygen-containing gas are used to perform plasma doping on the fin-semiconductor region (13). This forms impurity-doped region (17) in at least side portions of the fin-semiconductor region (13). |
US08574971B2 |
Method of manufacturing a thin-film transistor and method of manufacturing a display substrate using the same
An approach for patterning and etching without a mask is provided in a manufacturing a thin-film transistor, a gate electrode, a gate insulating layer, a semiconductor layer, an ohmic contact layer and source metal layer of a substrate. A first photoresist pattern including a first photo pattern and a second photo pattern is formed using a digital exposure device by generating a plurality of spot beams, the first photo pattern is formed to a first region of the base substrate and has a first thickness, and the second photo pattern is formed to a second region adjacent to the first region, and has a second thickness and a width in a range of about 50% to about 60% of a diameter of the spot beam. The source metal layer is patterned to form a source electrode and a drain electrode, and the source electrode and the drain electrode are spaced apart from each other in the first region of an active pattern. |
US08574967B2 |
Method for fabricating array-molded package-on-package
An improved semiconductor device package is manufactured by attaching semiconductor chips (130) on an insulating substrate (101) having contact pads (103). A mold is provided, which has a top portion (210) with metal protrusions (202) at locations matching the pad locations. The protrusions are shaped as truncated cones. The substrate and the chips are loaded onto the bottom mold portion (310); the mold is closed by clamping the top portion onto the bottom portion so that the protrusions approach the contact pads. Encapsulation compound is introduced into the cavity and the protrusions create apertures through the encapsulation compound towards the pad locations. |
US08574966B2 |
Semiconductor device having a semiconductor chip, and method for the production thereof
A semiconductor device having a semiconductor chip having an active surface with flip-chip contacts and a passive surface is disclosed. The flip-chip contacts are surrounded by an electrically insulating layer as underfill material, the layer having a UV B-stageable material. The UV B-stageable material is applied on the active surface of the semiconductor wafer. |
US08574964B2 |
Semiconductor device and method of forming electrical interconnection between semiconductor die and substrate with continuous body of solder tape
A semiconductor device has a flipchip type semiconductor die with contact pads and substrate with contact pads. A flux material is deposited over the contact pads of the semiconductor die and contact pads of the substrate. A solder tape formed as a continuous body of solder material with a plurality of recesses is disposed between the contact pads of the semiconductor die and substrate. The solder tape is brought to a liquidus state to separate a portion of the solder tape outside a footprint of the contact pads of the semiconductor die and substrate under surface tension and coalesce the solder material as an electrical interconnect substantially within the footprint of the contact pads of the semiconductor die and substrate. The contact pads on the semiconductor die and substrate can be formed with an extension or recess to increase surface area of the contact pads. |
US08574963B2 |
Method of manufacturing semiconductor device
Occurrence of a void is suppressed when mounting semiconductor chips over a wiring substrate via a paste-like adhesive material. A die bonding step is provided which mounts semiconductor chips over a chip-mounting region of the wiring substrate via the adhesive material. The wiring substrate includes a plurality of wirings (first wirings) and dummy wirings (second wirings) formed on an upper surface of a core layer. The chip-mounting region is provided over the first wirings and the second wirings. In addition, the die bonding step includes a step of applying the adhesive material over an adhesive material application region over the chip-mounting region. Each of the second wirings is extended along a direction in which the adhesive material spreads in the die bonding step. |
US08574961B2 |
Method of marking a low profile packaged semiconductor device
A semiconductor device (10) is made by mounting the bottom surfaces (31, 44, 54) of a semiconductor die (14) and a lead (15, 17) on a tape (12) and over a hole (19) in the tape. A vacuum is drawn through the hole to secure the die in place when the lead's top surface (43) is wirebonded to a top surface (32) of the semiconductor die. A molding material (49) is formed to encapsulate the top surface of the semiconductor die and to expose its bottom surface. |
US08574957B2 |
Method for manufacturing nonvolatile semiconductor memory element
An object of the present invention is to provide a method for manufacturing a variable resistance nonvolatile semiconductor memory element which can operate at a low voltage and high speed when initial breakdown is caused, and inhibit oxidization of a contact plug. The method for manufacturing the variable resistance nonvolatile semiconductor memory element, which includes a bottom electrode, a variable resistance layer, and a top electrode which are formed above a contact plug, includes oxidizing to insulate an end portion of the variable resistance layer prior to forming a bottom electrode by patterning a first conductive film. |
US08574949B2 |
Methods of building crystalline silicon solar cells for use in combinatorial screening
Embodiments of the current invention describe methods of forming different types of crystalline silicon based solar cells that can be combinatorially varied and evaluated. Examples of these different types of solar cells include front and back contact silicon based solar cells, all-back contact solar cells and selective emitter solar cells. These methodologies all incorporate the formation of site-isolated regions using a combinatorial processing tool and the use of these site-isolated regions to form the solar cell area. Therefore, multiple solar cells may be rapidly formed on a single crystalline silicon substrate for use in combinatorial methodologies. Any of the individual processes of the methods described may be varied combinatorially to test varied process conditions or materials. |
US08574944B2 |
System for selectively filling pin holes, weak shunts and/or scribe lines in photovoltaic devices and photovoltaic cells made thereby
A system for selectively filling pin holes, weak shunts and/or scribe lines in photovoltaics devices and photovoltaic cells made thereby is described. |
US08574935B2 |
Manufacturing method of solid state light emitting element
A manufacturing method of a solid state light emitting element is provided. A plurality of protrusion structures separated to each other are formed on a first substrate. A buffer layer is formed on the protrusion structures and fills the gaps between protrusion structures. An epitaxial growth layer is formed on the buffer layer to form a first semiconductor stacking structure. The first semiconductor stacking structure is inverted to a second substrate, so that the first semiconductor epitaxial layer and the second substrate are connected to form a second semiconductor stacking structure. The buffer layer is etched by a first etchant solution to form a third semiconductor stacking structure. A second etchant solution is used to permeate through the gaps between the protrusion structures, so that the protrusion structures are etched completely. The first substrate is removed from the third semiconductor stacking structure to form a fourth semiconductor stacking structure. |
US08574934B2 |
OVJP patterning of electronic devices
A method for forming an electronic device such as a passive color OLED display. Bottom electrodes are patterned onto a substrate in rows. Raised posts formed by photoresist are patterned into columns oriented orthogonally to the bottom row electrodes. One or more organic layers, such as R, G, B organic emissive layers are patterned over the raised posts and bottom electrodes using organic vapor jet printing (OVJP). An upper electrode layer is applied over the entire device and forms electrically isolated columnar electrodes due to discontinuities in the upper electrode layer created by the raised columnar posts. This permits patterning of the upper electrodes over the organic layers without using photolithography. A device formed by this method is also described. |
US08574932B2 |
PCB-mounted integrated circuits
A method and apparatus (20) for testing the mounting of an integrated circuit (16) on a printed circuit board (12) using a ball grid array comprises measuring the change in height, or drop, of the integrated circuit (16) relative to the printed circuit board (12) following soldering of the ball grid array and comparing the measured drop with a predetermined range. The integrated circuit is deemed to have been successfully mounted to the printed circuit board if the change in height falls within the predetermined range. |
US08574929B1 |
Method to form a 3D semiconductor device and structure
A method to form a monolithic 3D device including: processing a first layer including first mono-crystal transistors; transferring a second mono-crystal layer on top of the first layer including first mono-crystal transistors by using ion-cut layer transfer; and repairing the damage caused by the ion-cut by using optical annealing. |
US08574924B2 |
Assay device and method
An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion of a surface of a microfluidic chamber; passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface. |
US08574922B2 |
Targeted cell separation and enumeration device and the use thereof
This disclosure describes a portable device that conveniently applies cancer patient blood sample into a test strip to determine the level of the patient's metastatic circulating tumor cells. Proper use of this device provides end users with the diagnostic and prognostic information of the cancer patient, and any effect of applied therapies. The device can also be used to screen effective drugs for any known metastatic phenotype disruption. |
US08574920B2 |
Optical fiber polarimetric chemical sensor with modulated injection of sample fluid
An optical fiber polarimetric chemical sensor for capillary gas chromatography in which a sample fluid is injected into a capillary in the form of a periodic pulse train. Each individual pulse defines a moving polarization coupling zone that affects the polarization state of the light propagating in a birefringent optical waveguide that includes the capillary. The spacing between consecutive coupling zones can be made equal to the polarization beat length of the waveguide when the injection frequency of the pulses is properly selected, thus defining a resonance condition for a given analyte. The contributions of the successive coupling zones present along the length of the capillary then add up in phase, thus resulting in a detected optical signal having an enhanced amplitude peak at the injection frequency. In this manner, the sensitivity can be enhanced. |
US08574917B2 |
Hydrogen sulfide indicating pigments
Disclosed is a pigment that changes color upon exposure to hydrogen sulfide gas. The pigment may be ground or otherwise reduced to small particles and used in coatings, dyes, paints or inks. Potential applications for paints and inks include the production of warning indicators for the presence of hydrogen gas in areas where such presence may pose a hazard. Warning decals may be printed with pigmented ink and posted in areas of potential hydrogen hazard. In the presence of hydrogen sulfide gas, the decals can display a warning by causing a change in the color of a printed message. Objects may also be coated with pigmented paints so that if a hydrogen sulfide leak occurs from within or nearby the object, the color of the object changes to provide a warning of the presence of leaked hydrogen sulfide. Example applications of such painted objects include any industrial process containing hydrogen sulfide. |
US08574914B2 |
Methods for mobile zinc measurement
This invention relates to a method for using a zinc sensor compound to detect a disease associated with the disruption of zinc homeostasis, such as prostate cancer. The zinc sensor compound comprises an optical reporter having two or more recognition units where each of the recognition units is capable of associating with at least one zinc ion. |
US08574913B2 |
Method for measurement of hemoglobin and hemoglobin derivative, and measurement kit
Hemoglobin in a sample solution is quickly and reliably denatured; at the same time, quick and accurate measurement of hemoglobin and a hemoglobin derivative is realized. In a method for measuring hemoglobin and a hemoglobin derivative, and a reagent composition, a measurement kit, an analysis device, and an analysis system used in the method, a sample solution containing a blood component is treated with a nonionic surfactant, an oxidizing agent, and a metal salt to denature hemoglobin in the sample solution to measure the hemoglobin, and thereafter the amount of a hemoglobin derivative in the sample is measured by an immunological method using an antibody specifically binding to a denatured site of the denatured hemoglobin derivative. |
US08574911B2 |
Production and use of yeast having increased cellulose hydrolysis ability
The present invention provides a method for producing an yeast having an increased cellulose hydrolysis ability. The method includes the step of introducing increased integration copy numbers of both a gene for an enzyme capable of hydrolyzing crystalline cellulose and a gene for an enzyme capable of hydrolyzing noncrystalline cellulose into a noncellulolytic yeast to give a transformed yeast. The yeast having an increased cellulose hydrolysis ability can be suitably used for ethanol production from cellulose-based materials. |
US08574909B2 |
Saccharomyces cerevisiae yeast strain with functional expression of a GLUT transporter gene
The invention relates to a strain of the yeast Saccharomyces cerevisiae which, owing to deletion of the genomic sequences, no longer synthesizes hexose transporters and, as a consequence, can no longer grow on substrates with hexoses as the only carbon source, and whose ability of growing on a substrate with a hexose as the only carbon source is restored when it expresses a GLUT4 gene. |
US08574905B2 |
Hepatocyte lineage cells
Disclosed herein are methods for producing liver precursor cells as well as hepatocyte cells form pluripotent and/or multipotent cells. Also disclosed herein are methods of enriching isolating and/or purifying liver precursor cells and/or hepatocyte cells. Further disclosed are compositions comprising cell cultures and cell populations that are enriched for liver precursor cells or hepatocyte cells. |
US08574901B2 |
Cryoconserved mature dendritic cells
The invention relates to a method for producing ready to use, antigen loaded or unloaded, cryoconserved mature dendritic cells especially for the production of a vaccine containing said dendritic cells, wherein immature dendritic cells are cultivated in the presence of suitable maturation stimuli and the mature dendritic cells thus obtained are frozen. The dendritic cells can be loaded with antigen before freezing. The invention also relates to a vaccine which can be obtained according to the inventive method and to a composition containing frozen, mature dendritic cells which are loaded with antigen. |
US08574898B2 |
Translation-coupling systems
Disclosed are systems and methods for coupling translation of a target gene to a detectable response gene. A version of the invention includes a translation-coupling cassette. The translation-coupling cassette includes a target gene, a response gene, a response-gene translation control element, and a secondary structure-forming sequence that reversibly forms a secondary structure masking the response-gene translation control element. Masking of the response-gene translation control element inhibits translation of the response gene. Full translation of the target gene results in unfolding of the secondary structure and consequent translation of the response gene. Translation of the target gene is determined by detecting presence of the response-gene protein product. The invention further includes RNA transcripts of the translation-coupling cassettes, vectors comprising the translation-coupling cassettes, hosts comprising the translation-coupling cassettes, methods of using the translation-coupling cassettes, and gene products produced with the translation-coupling cassettes. |
US08574896B2 |
Colorimetric method and reagent used for the same
The present invention provides a colorimetric method that can perform a simple and reliable analysis in a short time. The method includes transferring an electron from an analyte to a coloring reagent that produces color by reduction via a mediator by using an oxidoreductase; and performing qualitative or quantitative analysis of the analyte by measuring color produced in the coloring reagent. The enzyme reaction of this method is a single stage reaction, and the color production reaction occurs via the mediator. Therefore, the measurement can be performed in a short time. Since this reaction requires neither hydrogen peroxide nor oxygen, the measured values are highly reliable. |
US08574893B2 |
Nucleic acid cleavage complex and method for using the same
A nucleic acid cleavage complex is disclosed, which includes: a nanoparticle, a nucleic acid cleavage reagent, and a polynucleotide chain specifically recognizing a sequence of a target nucleic acid and having a first terminal and a second terminal opposite to the first terminal, wherein the first terminal is connected to the nanoparticle, the second terminal is connected to the nucleic acid cleavage reagent, and the first terminal sequence and the second terminal sequence are base-paired to make the polynucleotide chain form a hairpin. Also, a method for using the nucleic acid cleavage complex is also disclosed. |
US08574892B2 |
Methods and apparatus for nucleic acid sequencing by signal stretching and data integration
The methods and apparatus 100 disclosed herein concern DNA sequencing. In some embodiments of the invention, the methods comprise measuring the distance between labeled nucleotides 220, such as nucleotides labeled with bulky groups. The methods may further comprise placing identical template DNA 200 into four reaction chambers 110, 120, 130, 140, each containing a different labeled nucleotide precursor, synthesizing complementary strands 230, 240, 250 and detecting labeled nucleotides 220. The distances between labeled nucleotides 220 may be used to construct 450 distance maps 310, 320, 330, 340 for each type of labeled nucleotide 220. The distance maps 310, 320, 330, 340 may be aligned 520 to obtain a nucleic acid sequence 210. Overlapping data analysis and frequency analysis may be used to construct 450 the distance maps 310, 320, 330, 340 and non-overlapping data analysis may be used to align 520 the distance maps into a sequence 210. |
US08574890B2 |
Nucleic acid extraction from complex matrices
The present disclosure describes an adsorbent and exemplary protocols for extracting nucleic acids, such as DNA and RNA, from complex matrices, such as stool samples and water samples. The adsorbent is activated charcoal coated with a material such as polyvinylpyrrolidone, dextran, or coconut flours. The adsorbent may be used in microcentrifuge spin columns, where it may be present as a slurry in a storage solution. The sample may be prepared by vortexing in a buffer solution, centrifuging, adding a protease to the supernatant, and passing the supernatant through a microcentrifuge spin column containing coated activated charcoal. The key components, including buffer, protease, and spin columns, may be packaged in a kit. |
US08574889B1 |
Method for processing biological material
The invention provides a process for producing ammonia or ammonium from an organic material, the method by contacting the organic material with at least one hydrolytic enzyme, in a medium, to produce a medium including hydrolyzed or partially hydrolyzed organic material suitable for microbial fermentation. The hydrolyzed or partially hydrolyzed medium with organic material is then fermented in the presence of at least one microorganism capable of ammonification, wherein the fermenting is under conditions, and for a sufficient period of time, to produce a fermentation product that comprises ammonia or ammonium. The organic material includes nitrogenous compounds suitable for conversion to ammonia or ammonium. |
US08574881B2 |
Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes
The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties. |
US08574869B2 |
Prevention of disulfide bond reduction during recombinant production of polypeptides
Provided herein are methods for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures. |
US08574868B2 |
Method for deparaffinizing formalin-fixed paraffin-embedded tissue
The invention provides a method for deparaffinizing a formalin-fixed paraffin-embedded tissue, including: providing a formalin-fixed paraffin-embedded tissue sample; mixing the formalin-fixed paraffin-embedded tissue sample with an organic solvent and water or with an organic solvent and an aqueous solution to form a mixture, wherein a density of the organic solvent is less than that of the water or the aqueous solution, and the organic solvent is immiscible with the water or the aqueous solution; and separating the mixture into an organic solution layer and an aqueous solution layer, wherein a paraffin dissolved from the formalin-fixed paraffin-embedded tissue sample is in the organic solution layer and a deparaffinized tissue from the formalin-fixed paraffin-embedded tissue sample is in the aqueous solution layer and/or an interlayer between the organic solution layer and the aqueous solution layer. |
US08574863B2 |
Alkaline phosphatase for treating an inflammatory disease of the gastro-intestinal tract
The present invention provides a use for alkaline phosphatase for the manufacture of a medicament for the prevention or reduction of toxic LPS influx through a mucosal lining of a mammalian body cavity. A source of alkaline phosphatase is administered for the prophylaxis or treatment of LPS mediated or exacerbated diseases. The invention also provides compositions comprising a source of alkaline phosphatase for the prevention or reduction of (toxic) LPS influx or passage through mucosal layers. |
US08574860B2 |
Biomarkers for the detection and screening of down syndrome
The disclosure includes assays and methods for screening for risk of Down syndrome and/or trisomy 21 in a fetus. The assays and methods comprise determining the level of at least one biomarker selected from mucin 13 (MUC13), bile salt-activated lipase (CEL), dipeptidyl peptidase 4 (DPP4), carboxypeptidase A1 (CPA1), amyloid precursor protein (APP) and tenascin-C (TNC-C) polypeptides in a test biological sample from a pregnant subject, wherein a decreased level of MUC13, CEL, DPP4, and/or CPA1 polypeptide and/or an increased level of APP and/or TNC-C polypeptide in the test biological sample compared to a corresponding reference biomarker polypeptide level indicates an increased risk of Down syndrome or trisomy 21 in the fetus. The disclosure also includes assays, compositions, immunoassays, and kits for performing the methods disclosed herein. |
US08574858B2 |
Autoantibody enhanced immunoassays and kits
The present disclosure provides immunoassays and kits for detection or quantification of an analyte of interest in a test sample that potentially contains endogenously produced autoantibodies reactive with the analyte. |
US08574857B2 |
Method and means for treatment of osteoarthritis
The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean cartilage thickness in a subject. |
US08574854B2 |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
Described herein are compositions and methods of use of anti-pancreatic cancer antibodies or fragments thereof, such as murine, chimeric, humanized or human PAM4 antibodies. The antibodies show novel and useful diagnostic characteristics, such as binding with high specificity to pancreatic and other cancers, but not to normal or benign pancreatic tissues and binding to a high percentage of early stage pancreatic cancers. Preferably, the antibodies bind to pancreatic cancer mucins such as MUC1 or MUC5ac and are of use for the detection and diagnosis of early stage pancreatic cancer. In more preferred embodiments, the anti-pancreatic cancer antibodies can be used for immunoassay of serum samples, wherein the immunoassay detects a marker for early stage pancreatic cancer in serum. Most preferably, the serum is extracted with an organic phase, such as butanol, before immunoassay. Alternatively, immunoassay with PAM4 and anti-CA19.9 antibodies may be utilized to improve sensitivity for pancreatic cancer. |
US08574851B2 |
Prediction and prevention of preeclampsia
The present disclosure relates to methods for detecting an increased risk of preeclampsia, determining the presence of preeclampsia, reducing the likelihood that preeclampsia will develop and treating preeclampsia. It also provides methods of measuring relaxin levels in a biological sample of a pregnant woman. |
US08574850B2 |
Use of secretor, lewis and sialyl antigen levels in clinical samples as predictors of risk for disease
An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y). |
US08574846B2 |
Recombinase polymerase amplification
This disclosure describes related novel methods for Recombinase-Polymerase Amplification (RPA) of a target DNA that exploit the properties of recombinase and related proteins, to invade double-stranded DNA with single stranded homologous DNA permitting sequence specific priming of DNA polymerase reactions. The disclosed methods have the advantage of not requiring thermocycling or thermophilic enzymes. Further, the improved processivity of the disclosed methods may allow amplification of DNA up to hundres of megabases in length. |
US08574838B2 |
Methods and kits for miRNA isolation and quantitation
The present invention is a kit and method for isolating and quantitating miRNA and to the use of such methods in the diagnosis and prognosis of disease. |
US08574836B2 |
Method and apparatus for chromosome profiling
A method and apparatus for generating an Interphase chromosome profile. The method comprises obtaining a sample containing cells having chromosomes for profiling; obtaining species specific DNA probes, wherein the DNA probes are capable of marking at least one chromosome at substantially equidistant locations on said chromosome; hybridizing the sample with the DNA probes with plurality of fluorescent labels; and using visual analysis for determining the profile of the chromosome. |
US08574833B2 |
Methods and compositions for amplifying a detectable signal
Methods and materials are disclosed relating to an improved method for amplifying a signal in a diagnostic assay for a nucleic acid, comprising the steps of providing an amplification polymer bound to a nucleic acid analyte, wherein the amplification polymer comprises a plurality of amine groups; binding amine groups on the amplification polymer with a detectable label complex; and reacting under high salt conditions an acetylating compound with amine groups not bound with a detectable label complex. |
US08574832B2 |
Methods for preparing sequencing libraries
Improvements in chromatin immunoprecipitation-high throughput sequencing techniques has allowed the creation of chromatin maps from limited biological sample sizes that cannot be evaluated using conventional chromatin immunoprecipitation-sequencing protocols. For example, a modified universal primer is utilized that incorporates restriction enzymes into chromatin immunoprecipitation fragments before amplification. The improved method allows the sample sizes to be several orders of magnitude less than that required for standard ChIP-Seq techniques. |
US08574823B2 |
Multi-level layer
Various methods and apparatus relating to a multi-level layer are disclosed. |
US08574821B1 |
MEMS fabrication process base on SU-8 masking layers
A novel fabrication process uses a combination of negative and positive photoresists with positive tone photomasks, resulting in masking layers suitable for bulk micromachining high-aspect ratio microelectromechanical systems (MEMS) devices. This technique allows the use of positive photomasks with negative resists, opening the door to an ability to create complementary mechanical structures without the fabrication delays and costs associated with having to obtain a negative photomask. In addition, whereas an SU-8 mask would normally be left in place after processing, a technique utilizing a positive photoresist as a release layer has been developed so that the SU-8 masking material can be removed post-etching. |
US08574820B2 |
Method for fabricating semiconductor device
A method for fabricating a semiconductor device includes: forming a first photoresist pattern with a first opening over an etch target layer; forming a second photoresist pattern with a plurality of second openings over the first photoresist pattern; and forming a plurality of patterns by etching the etch target layer by using the first photoresist pattern and the second photoresist pattern as an etch barrier. |
US08574817B2 |
Positive resist composition and patterning process
A positive resist composition comprising a polymer having carboxyl groups substituted with an acid labile group having formula (1), (2) or (3) exhibits a high contrast of alkaline dissolution rate before and after exposure, a high resolution, a reduced acid diffusion rate, and forms a pattern with good profile, minimal edge roughness, and etch resistance. In formula (1), R1, R2, R5, R6, R8, and R9 are alkyl, aryl, or alkenyl, R3, R4, R7, R10, and R11 are hydrogen, alkyl, alkoxy, acyloxy, halogen, cyano, nitro, hydroxyl or trifluoromethyl, M is methylene or ethylene, R is a single bond or linking group. |
US08574813B2 |
Resist composition for immersion exposure and method of forming resist pattern
A resist composition for immersion exposure and a method of forming a resist pattern which can satisfy both of excellent resistance to an immersion medium and lithography properties. The resist composition for immersion exposure includes a resin component (A) which exhibits changed alkali solubility under action of acid and an acid-generator component (B) which generates acid upon irradiation, the resin component (A) including a resin (A1) which contains a fluorine atom and a resin (A2) which has a structural unit (a′) derived from acrylic acid and contains no fluorine atom, and the amount of the resin (A1) contained in the resin component (A) being within the range from 0.1 to 50% by weight. |
US08574810B2 |
Dual tone development with a photo-activated acid enhancement component in lithographic applications
A method and system for patterning a substrate using a lithographic process, such as a dual tone development process, is described. The method comprises use of at least one photo-activated acid enhancement component to improve process latitude for the dual tone development process. |
US08574806B2 |
Image forming method
An image forming method including a process for forming a transparent toner layer on an image formed on a support, the method including steps of supplying a transparent toner on an image on a support, and heating and then cooling the image on the support having the transparent toner while the image on the support having the transparent toner being in contact with a belt, wherein the transparent toner contains a resin constituted by a polyester and a styrene-acryl copolymer, a monoester compound represented by Formula I, and a hydrocarbon compound having at least one of a branched chain structure and a cyclic structure, R1—COO—R2 Formula I: wherein, R1 and R2 are each a hydrocarbon group having 13 to 30 carbon atoms which may have a substituent or not, and R1 and R2 are the same or different. |
US08574791B2 |
Method for production of a solid oxide fuel cell (SOFC)
A method for production of a solid oxide fuel cell (SOFC) (1), having an electrolyte body (10) with a tubular structure, wherein at least one internal electrode (11) and one external electrode (12) are applied to the tubular electrolyte body, with the method having at least the following steps: provision of an injection molding core (13) on which at least one interconnector material (14) and the internal electrode (11) are mounted, arrangement of the injection molding core (13) in an injection mold (25a, 25b), injection molding of an electrolyte compound (10a) in order to form the electrolyte body (10), and removal of the injection molding core (13) in the form of a casting process with a lost core. |
US08574789B2 |
Dendritic metal nanostructures for fuel cells and other applications
Embodiment of the present invention relate to dendrimers useful for application as catalysts, in particular as improved electrocatalysts for polymer electrolyte membrane fuel cells (PEM-FCs). Methods of preparing such catalysts are described. Examples include dendritic nanostructured metal catalysts, such as platinum and platinum-alloy catalysts. |
US08574786B2 |
Anode catalysts for fuel cell membrane reactors
Anode catalysts for conversion of hydrocarbon feeds in solid oxide fuel cell membrane reactors. An anode catalyst may be a mixture of a metal with a metal oxide, for example a mixture of copper or copper-nickel alloy or copper-cobalt alloy with Cr2O3. Mixed oxides can be prepared by dissolving into water soluble salts of the different metals, chelating the metal ions with a chelating agent, neutralizing the solution, removing water by evaporation to form a gel which then is dried, and finally heating the dried gel to form a mixed oxide of the different metals. The chelating agent can be citrate ions, and ammonia can be added to the solution until the pH of the solution is about 8. The mixed oxide so formed then is reduced, for example by hydrogen, to form a composite comprising the metal (Cu, Cu—Co, Cu—Ni) and metal oxide, here Cr2O3. Typically, the composite oxides so formed comprise approximately spherical nanoparticles, and the reduced composites are nanoparticles comprising very small particles of the metal within a network of the oxide, Cr2O3. |
US08574785B2 |
Membrane-electrode assembly for fuel cell with binder layer having inorganic additive and fuel cell system using the same
The present invention relates to a membrane-electrode assembly for a fuel cell and a fuel cell system comprising the same. The membrane-electrode assembly includes an anode and a cathode facing each other and a polymer electrolyte membrane positioned therebetween. The polymer electrolyte membrane adheres to the anode through a binder disposed between the polymer electrolyte membrane and the anode, and adheres to the cathode through a binder disposed between the polymer electrolyte membrane and the cathode. The binder and the polymer electrolyte membrane can include a cation exchange resin and an inorganic additive. |
US08574782B2 |
Fuel cell repeater unit including frame and separator plate
An example fuel cell repeater includes a separator plate and a frame establishing at least a portion of a flow path that is operative to communicate fuel to or from at least one fuel cell held by the frame relative to the separator plate. The flow path has a perimeter and any fuel within the perimeter flow across the at least one fuel cell in a first direction. The separator plate, the frame, or both establish at least one conduit positioned outside the flow path perimeter. The conduit is outside of the flow path perimeter and is configured to direct flow in a second, different direction. The conduit is fluidly coupled with the flow path. |
US08574781B2 |
Fuel cell stack
A fuel cell stack. A fuel cell stack, an example of the fuel cell stack, is configured by alternately overlaying first electricity generating units and second electricity generating units in the horizontal direction. The first electricity units are each provided with a first fuel gas flow path, a first oxidant gas flow path, a second fuel gas flow path, and a second oxidant gas flow path, and the flow paths are set to the same phase in the overlaying direction. The second electricity generating units are each provided with a first fuel gas flow path, a first oxidant gas flow path, a second fuel gas flow path, and a second oxidant gas flow path which are set to the same phase in the overlaying direction and are set to a phase different from the phase of the flow paths of the first electricity generating units. |
US08574780B2 |
Fuel cell separator with chromium rich surface layer and method of producing the fuel cell separator
The present invention relates to a fuel cell separator and a method of producing the fuel cell separator. A first separator and a second separator are provided as the fuel cell separators. Firstly, the first separator and the second separator are heated. Thus, an Fe rich layer is formed in a surface layer of each of the first separator and the second separator, and a Cr rich layer where a proportion of Cr is 60% or more is formed in an inner portion of each of the first separator and the second separator. Then, an electrolytic treatment is applied to each of the first separator and the second separator to remove the Fe rich layer. By the removal, the Cr rich layer is exposed to the outside on the outermost surface layer of each of the first separator and the second separator. |
US08574777B2 |
Fuel cell system
There is disclosed a fuel cell system capable of stably operating auxiliary devices driven at a high voltage and the like, even in a case where a poisoned electrode catalyst is recovered or a fuel cell is warmed up. On detecting that the electrode catalyst is poisoned, a controller derives a target operation point which is sufficient for recovering an activity of the poisoned electrode catalyst. Then, shift of the operation point from a usual operation point to a low-efficiency operation point is realized so that an output power is held to be constant. |
US08574772B2 |
Solid electrolyte, solid electrolyte sheet, and method for producing solid electrolyte
The main object of the present invention is to provide a solid electrolyte with intergranular resistance decreased.The present invention solves the above-mentioned problem by providing a solid electrolyte comprising a garnet-type compound with Li ion conductivity as the main component, characterized in that a phosphate group-containing Li ion conductor is provided between particles of the above-mentioned garnet-type compound, and the phosphate group-containing Li ion conductor has a smaller particle diameter than a particle diameter of the above-mentioned garnet-type compound and makes face contact with the above-mentioned garnet-type compound. |
US08574769B2 |
Manufacturing method for polyimide separator
A separator includes a separator body and a first film. The separator body is formed by mixing and solidifying a first material and a second material and then removing the first material by an alkaline liquid etching process. The separator body has a plurality of irregular holes formed corresponding to the removed first material. The first film is disposed on one side of the separator body. |
US08574767B2 |
Thin film electrodes including metal tubes filled with active material and battery cells, and methods of fabrication
Thin-film electrodes and battery cells, and methods of fabrication. A thin film electrode may be fabricated from a non-metallic, non-conductive porous support structure having pores with micrometer-range diameters. The support may include a polymer film. A first surface of the support is metalized, and the pores are partially metallized to create metal tubes having a thickness within a range of 50 to 150 nanometers, in contact with the metal layer. An active material is disposed within metalized portions of the pores. An electrolyte is disposed within non-metalized portions of the pores. Active materials may be selected to create an anode and a cathode. Non-metalized surfaces of the anode and cathode may be contacted to one another to form a battery cell, with the non-metalized electrolyte-containing portions of the anode facing the electrolyte-containing portions of the cathode pores. A battery cell may be fabricated as, for example, a nickel-zinc battery cell. |
US08574765B2 |
Li-Ni composite oxide particles for non-aqueous electrolyte secondary battery, process for producing the same, and non-aqueous electrolyte secondary battery
Li—Ni composite oxide particles for a non-aqueous electrolyte secondary battery with a large charge/discharge capacity and excellent thermal stability in a charged condition. The Li—Ni composite oxide secondary particles form core particles having a composition Lix1Ni1-y1-z1-w1Coy1Mnz1Mw1O2 in which 0.9≦x1≦1.3; 0.1≦y1≦0.3; 0.0≦z1≦0.3; 0≦w1≦0.1; and M is Al or Fe. The Li—Ni composite oxide has a composition Lix2Ni1-y2-z2-w2Coy2Mnz2Mw2O2 in which 0.9≦x2≦1+z2; 0≦y2≦0.33; 0≦z2≦0.5; 0≦w2≦0.1; and M is Al, Fe, Mg, Zr or Ti and is coated or present on a surface of the secondary particles. |
US08574763B2 |
Electrode plate with a binder in a surface section with a lower glass transition point than a binder in a current collector plate section, secondary battery, and method for producing the electrode plate
An electrode plate includes a current collector plate and an active material layer formed thereon. The active material layer includes, as a binder, a plurality of binders having different glass transition points (Tg) from each other. A ratio (A2/A1) between the amount of a binder contained in a surface section and the amount of a binder contained in a current collector plate section is 1.0 to 1.2. Further, an average glass transition point (Tgu) of the binder in the surface section is lower than an average glass transition point (Tgd) of the binder in the current collector plate section (Tgu |
US08574762B2 |
Metal oxide negative electrodes for lithium-ion electrochemical cells and batteries
Provided are negative electrode compositions for lithium-ion electrochemical cells that include metal oxides and polymeric binders. Also provided are electrochemical cells and battery packs that include electrodes made with these compositions. |
US08574760B2 |
Safety-enhanced electrochemical device including electrode containing binder and wax
The present invention relates to an electrode comprising electrode active material particles, conductive particles, a binder and wax, wherein the electrode active material particles are interconnected by a network of the conductive particles, and the paths of the conductive particles interconnecting the electrode active materials are partially or entirely fixed by the wax. Furthermore, the present invention provides an electrochemical device comprising the electrode.By use of wax having a low meting viscosity in order to partially or entirely fix the paths of the conductive particles, which interconnect the spaced electrode active material particles, the present invention can improve processability and safety of the electrochemical device. |
US08574738B2 |
Battery pack assembly with integrated heater
A battery pack assembly for providing electric power to a load includes a battery pack, preferably made up of a plurality of lithium ion cells. A heating device formed of a flexible material flexes and covers at least part of the battery pack. The heating device includes a meandering heating strip. A thermal sensor is surrounded by the heating strip to sense the temperature of the battery pack. Electric current is applied to the heating strip to heat the battery pack when its temperature falls too low, thus improving performance of the battery pack. The heating device also includes a plurality of tabs extending beyond the peripheral sides of the heating device for direct connection to the cells. Thus, electric current for the heating strip is provided directly from the cells of the battery pack. |
US08574737B2 |
Bioelectric battery for implantable device applications
A bioelectric battery may be used to power implantable devices. The bioelectric battery may have an anode electrode and a cathode electrode separated by an insulating member comprising a tube having a first end and a second end, wherein said anode is inserted into said first end of said tube and said cathode surrounds said tube such that the tube provides a support for the cathode electrode. The bioelectric battery may also have a membrane surrounding the cathode to reduce tissue encapsulation. Alternatively, an anode electrode, a cathode electrode surrounding the cathode electrode, a permeable membrane surrounding the cathode electrode. An electrolyte is disposed within the permeable membrane and a mesh surrounds the permeable membrane. In an alternative embodiment, a pacemaker housing acts as a cathode electrode for a bioelectric battery and an anode electrode is attached to the housing with an insulative adhesive. |
US08574736B2 |
Hybrid-typed electrode assembly of capacitor-battery structure
Disclosed herein are a hybrid type electrode assembly including a plurality of electrode groups that can be charged and discharged, wherein the respective electrode groups are constructed in a structure in which a cathode and an anode are opposite to each other while a separator is disposed between the cathode and the anode, and at least one of the electrode groups is a capacitor type electrode group, and a secondary battery including the same. In the hybrid type electrode assembly according to the present invention, a coupled system of a capacitor and a secondary battery is embodied in a single cell through a simplified manufacturing process. Consequently, the present invention has the effect of reducing the manufacturing costs of the battery cell and improving the pulse charge and discharge characteristics without the degeneration of capacity. |
US08574734B2 |
Vehicle battery temperature control system containing heating device and method
A vehicle battery temperature control system includes a battery, a heating device, a housing, a heat exchanger and a sensor. The battery has a heat sink that transfers thermal energy to the battery. The heating device is selectively operable to provide thermal energy. The housing includes a chamber that contains the battery and a saturated liquid coolant that substantially immerses the heat sink, and the coolant receives the thermal energy from the heating device to cause a phase change of the coolant from liquid to vapor to heat the heat sink which heats the battery. The heat exchanger removes thermal energy from the vapor to change the vapor to liquid and returns the liquid to the chamber. The sensor detects a characteristic of the vapor and signals operation of the heating device to provide the thermal energy based on a relationship between the characteristic and a threshold. |
US08574733B2 |
Protection circuit for secondary battery and secondary battery comprising the same
Disclosed is a protection circuit for a secondary battery and a secondary battery having the same, which can interrupt electric current input into the secondary battery when the temperature of the secondary battery increases due to an overcharge, and also can protect the secondary battery in the case where the already charged secondary battery is exposed to a high temperature due to the increase of an external or internal temperature of the secondary battery. The protection circuit includes: means having one end connected to a first electrode of the secondary battery, for restricting electric current; switching means for connecting a second electrode of the secondary battery to a first outer electrode, or to the current restriction means in response to temperature; and a conducting wire for connecting the first electrode of the secondary battery to a second outer electrode. |
US08574724B2 |
Organic electroluminescent device, method for manufacturing the organic electroluminescent device, and electronic apparatus
An organic electroluminescent device includes a pair of electrodes, and a first organic layer and a second organic layer in contact with each other formed between the electrodes by a wet process. The first organic layer contains a crosslinkable organic material and includes a crosslinked layer formed by crosslinking the crosslinkable organic material at least at the interface with the second organic layer. |
US08574723B2 |
Sandwich material for brazing with high strength at high temperature
The invention relates to a sandwich material for brazing comprising a core layer of a first aluminum alloy and a barrier layer of a second aluminum alloy characterized by that: the first alloy, constituting the core layer contains (in weight %): 0.8-2% Mn, ≦1.0% Mg, 0.3-1.5% Si, ≦0.3% Ti, ≦0.3% Cr, ≦0.3% Zr, ≦1.3% Cu, ≦0.5% Zn, ≦0.2% In, ≦0.1% Sn and ≦0.7% (Fe+Ni), the balance consisting of Al and ≦0.05% of each of the unavoidable impurities, and that the second alloy, constituting the barrier layer contains (in weight %): ≦0.2% Mn+Cr, ≦1.0% Mg, ≦1.5% Si, ≦0.3% Ti, ≦0.2% Zr, ≦0.3% Cu, ≦0.5% Zn, ≦0.2% In, ≦0.1% Sn and ≦1.5% (Fe+Ni), the balance consisting of Al and ≦0.05% of each of the unavoidable impurities, The invention also concerns a method for the manufacture of the sandwich material, a brazed product, such as a heat exchanger comprising the sandwich material and the use of the brazed product at high and low temperatures. |
US08574719B2 |
Anti-fouling coating compositions containing a carboxyl-functional organosilicone
An anti-fouling coating composition comprising (i) a curable polymer and (ii) an organosilicone polymer. This anti-fouling coating composition has a low surface energy, has suitable elastomeric properties, decreases the settlement of fouling organisms and their adhesion strength, and can be used as a clear coat without a misty or milky appearance. |
US08574715B2 |
Laminated film and laminated film-coated member
A laminated film is provided which exhibits excellent durability even when formed over a surface of a member (in particular, sliding member) to be used under a high pressure of contacted surface of 2.0 GPa or more. The laminated film includes an intermediate layer which contains one or more compounds selected from the group consisting of a carbide, a boride, and a boron carbide compound of a metal element, and which has a hardness measured by a nanoindentation method (hereinafter referred to as a “nanoindentation hardness”) of not less than 20 GPa nor more than 35 GPa and a thickness of not less than 5 μm nor more than 10 μm, and a diamond-like carbon film which is formed over the intermediate layer, and which has a nanoindentation hardness of not less than 25 GPa nor more than 35 GPa and a thickness of not less than 0.3 μm nor more than 1.0 μm. |
US08574714B2 |
Method of manufacturing an engraved plate
A method of manufacturing an engraved plate used in intaglio printing, said plate being engraved by a tool, for example a laser beam, characterized in that the engraving tool uses data from a depth-map, based on a three-dimensional raster image of the document to be printed. |
US08574709B2 |
Deposition donor substrate and method for manufacturing light-emitting device
One surface of a first substrate provided with at least light-absorbing layers separately formed, partition layers each formed between the light-absorbing layers and having an inverse taper shape, and material layers formed on the light-absorbing layers and on the partition layers so that the material layers are separated from each other is disposed to face a deposition target surface of a second substrate; light irradiation is performed from the other surface of the first substrate, only the material layers in regions overlapped with the light-absorbing layers are heated and evaporated to the deposition target surface of the second substrate. |
US08574707B2 |
Molded resin product and process for surface treatment thereof
A molded resin product includes a substrate made of a transparent resin, opaque coating film disposed on rear surface of the substrate except for an area set aside for a patterned portion, a transparent resin material disposed in the area set aside for the patterned portion on the rear surface of the substrate, and an opaque reflection coating or a half-reflective coating laminated to the transparent resin material. Under this configuration, the patterned portion looks as if it pops up from the rear surface of the substrate. If a half-reflective coating is used, the pattern is visible through the half-reflective coating when the pattern is viewed from the rear surface of the lid of a molded resin product. |
US08574704B2 |
Liquid-impregnated surfaces, methods of making, and devices incorporating the same
The invention is directed to an article with a liquid-impregnated surface, the surface having a matrix of features thereupon, spaced sufficiently close to stably contain a liquid therebetween or therewithin, and preferable also a thin film thereupon. The surface provides the article with advantageous non-wetting properties. Compared to previous non-wetting surfaces, which include a gas (e.g., air) entrained within surface textures, these liquid-impregnated surfaces are resistant to impalement and frost formation, and are therefore more robust. |
US08574696B2 |
Electronic device housing assembly
An electronic device comprising a housing assembly having at least one fiber composite layer molded into a portion of the housing assembly, the at least one fiber composite layer having a warp direction and configured to provide strength to the housing assembly corresponding to the warp direction. |
US08574694B2 |
Packaging sheet with improved cutting properties
A non-oriented thermoformable packaging sheet having a rigid component layer comprising a blend of an aromatic polyester and a styrenic polymer, where the total amount of styrenic polymer present in the sheet relative to the total weight of the sheet is at least between 3.0% and 4.0% by weight. The packaging sheet has a thickness of at least 5 mil and a normalized impact strength of 0.16 ft*lbf/mil or less total energy as measured in accordance with ASTM D3763-08 test method. |
US08574685B1 |
Electric field tuning of PbS quantum dots for high efficiency solar cell application
A thin film and a method of making a thin film. The thin film comprises a patterned substrate, a smooth film of electric field tuned quantum dots solution positioned on the patterned substrate, and a thin layer of metal positioned on the thin film. The method begins by drop-casting a quantum dots solution onto a patterned substrate to create a thin film. While the quantum dots solution is drying, a linearly increasing electric filed is applied. The thin film is then placed in a deposition chamber and a thin layer of metal is deposited onto the thin film. Also included are a method of measuring the photoinduced charge transfer (PCT) rate in a quantum dot nanocomposite film and methods of forming a Shottky barrier on a transparent ITO electrode of a quantum dot film. |
US08574684B2 |
Method and apparatus for aligning a support with respect to a honeycomb body
Method is provided for applying a cement mixture to a honeycomb body including the step of aligning a first end of the honeycomb body with respect to a first longitudinal axis of a first support member. The method further includes the step of aligning a second support member with respect to the second end of the honeycomb body. The second support member is allowed to move relative to the first support member such that a second longitudinal axis of second support member is not coincident with the first longitudinal axis. The method further includes the step of fixing the position of the honeycomb body with respect to the first support member and the second support member. The method still further includes the step of applying a cement mixture to the honeycomb body. An apparatus is provided that is configured to apply a cement mixture to a honeycomb body. |
US08574683B2 |
Method of making a pulp sheet of odor-inhibiting absorbent fibers
An odor-inhibiting fiber having a cellulosic fiber and an odor-inhibiting formulation. The odor-inhibiting formulation may contain an odor-inhibiting agent, such as a biocide, an enzyme, a urease inhibitor. The odor-inhibiting formulation also may contain a liquid carrier such as a hydrophobic or hydrophilic organic liquid, or a mixture of a hydrophobic and hydrophilic organic liquid. The cellulosic fiber is impregnated with the odor-inhibiting formulation to produce fiber having odor-inhibiting characteristics. The resultant odor-inhibiting fiber is useful in making absorbent articles with odor-inhibiting characteristics. The fiber of the embodiments prevents odor by inhibiting bacteria growth and ammonia production, especially when used in an absorbent article such as a diaper or adult incontinence device. |
US08574682B1 |
Housing and method for making same
A housing includes a plastic substrate and a layer formed on the plastic substrate. The layer contains polysiloxane and epoxy resin. The layer is very thin, but evenly forms on the surface of the plastic substrate. The layer has a high hardness and can effectively protect the plastic substrate from abrasion. |
US08574679B2 |
Substrate structure and manufacturing method of the same
With TiN being a base material, TiN fine particles are deposited on a silicone substrate by, for example, a laser ablation method so that diameters of the TiN fine particles are about 3 nm, and thereafter, Co fine particles are deposited on the silicon substrate on which the TiN fine particles are deposited, by, for example, the laser ablation method so that sizes of the Co fine particles are equal to or smaller than sizes of the fine particles of the TiN fine particles, here about 1 nm in diameter. |
US08574672B2 |
Polyester polymer and coating compositions thereof
A polymer and coating compositions containing the polymer are provided that are useful in coating applications such as, for example, food or beverage packaging coatings. The polymer preferably includes a polyester backbone and at least one deblockable isocyanate group attached to the backbone. In one embodiment, the polymer includes a polyester-carbamate backbone, one or more pendant deblockable isocyanate groups, and one or more terminal or pendant isocyanate-reactive groups. The deblockable isocyanate groups may be provided, for example, through use of a partially blocked polyisocyanate. |
US08574667B2 |
Methods of forming coatings upon wellbore tools
A composition including a high temperature thermoplastic polymer and a filler material is disclosed. A method for forming a coating upon a wellbore tool includes forming a powder composition comprising a thermoplastic polymer and a filler material and applying the composition on the body surface. Wellbore tools having components coated with such compositions are also disclosed. |
US08574655B2 |
Packaged beverage with caffeine-containing catechin composition
A process for selectively removing caffeine from a caffeine-containing catechin composition, which includes dissolving the caffeine-containing catechin composition in a 9/1 to 1/9 by weight mixed solution of an organic solvent and water, and then bringing the resultant solution into contact with activated carbon alone or with activated carbon and also acid clay or activated clay; and a packaged beverage containing such a decaffeinated composition. |
US08574653B2 |
Intermittent flow extrusion process and food product
An extrusion process incorporates a forming manifold where a tubular flow of a second material is intermittently interrupted while a core flow of a first material is discharged substantially continuously. Subsequently, the core flow is severed to form individual food items or treats for humans, animals, and the like, where the tubular flow results in an outer component surrounding an inner component which protrudes from one or both ends of the outer component. Material of the core flow is bone-like, while material of the tubular flow is meat like. Material of the tubular flow may include material from the core flow subjected to mixing in a static mixer to achieve a marbled texture of the outer material. |
US08574649B2 |
Stove and method for preventing cooked material from being burnt dry
A stove and a method for preventing a cooked material from being burnt dry are provided. The stove includes a stove body for heating the cooked material, a weighing unit for generating a weighing signal of the cooked material, a monitoring unit for judging whether the user is managing the cooked material, and a computing unit. The weighing signal is changed with time. A plurality of weighing signal change amounts respectively generated within a plurality of time intervals are calculate by the computing unit. According to the weighing signal change amounts, the heat source of the stove body is adjusted. Consequently, the function of preventing the cooked material from being burnt dry will be achieved. |
US08574646B2 |
Package for molded food product
A solid food product is molded in a mold cavity and is thereafter packaged in the mold cavity. The mold cavity is formed in a sheet and includes a side wall which extends from the sheet and a bottom wall which includes an inverting portion which extends from said side wall and a central portion. The central potion of the bottom wall includes a plurality of ridges which form a decorative design. A liquid food product is introduced into the mold cavity and allowed to solidify to form a molded solid food product. The central portion of the bottom wall is thereafter pushed into the mold cavity to invert said inverting potion and to push the molded food product away from the central portion of the bottom wall. The molded food product includes ridges which correspond to the ridges in the bottom wall of the mold cavity. A lid is attached to the sheet to enclose and package the molded food product within the mold cavity. |
US08574645B2 |
Antimicrobial composition
The present invention describes a process to preserve a water-containing product such as a foodstuff, which comprises adding natamycin and nisin to the product, whereby at least 90% (w/v) of natamycin is dissolved and/or less than 10% (w/v) of natamycin is present in crystal form. |
US08574634B2 |
Compositions and methods of treatment with proanthocyanidin polymer antidiarrheal compositions
Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from a Croton spp. or a Calophyllum spp. In particular, the invention relates to a formulation of a proanthocyanidin polymer composition which protects the composition from the effects of stomach acid after oral administration, particularly to those formulations which are enteric coated. The invention also relates to methods of producing a directly compressible proanthocyanidin polymer composition, as well as compositions containing the directly compressible proanthocyanidin polymer composition. |
US08574631B2 |
Water-dispersible pellets containing a isobutylene diurea and a lignin binder
Water-dispersible particles are provided that disperse into more than 100 pieces upon contact with water. Particles include from 5% to 99.9% of a nitrogen-containing ingredient bioavailable to a targeted desirable organism and 1% to 95% of a bentonite binder component.Additionally provided is a process for making a water-dispersible particle, the process including the steps of mechanically aggregating particle components into a pellet. Particle components include a bioavailable nitrogen-containing ingredient and a binder, the components being such that a product particle is dispersed into more than 100 pieces upon contact with water. In a further step of a process for making a water-dispersible particle, the pellet is dried to form a particle. Following administration of a described particle, water is allowed to contact the particle, dispersing it into pieces and thereby delivering a nutrient. |
US08574627B2 |
Coated surgical mesh
A surgical mesh is formed of a biocompatible mesh structure with a coating that provides anti-inflammatory, non-inflammatory, and anti-adhesion functionality for a implantation in a patient. The coating is generally formed of a fish oil, can include vitamin E, and may be at least partially cured. In addition, the coating can include a therapeutic agent component, such as a drug or other therapeutic agent. |
US08574623B2 |
Therapeutic agent for pulmonary fibrosis
Disclosed are: a substance transfer carrier to an extracellular matrix-producing cell in the lung, which comprises a retinoid; a therapeutic agent for pulmonary fibrosis, which utilized the carrier; and a preparation kit of the therapeutic agent. |
US08574622B2 |
Controlled release delivery system for nasal applications
This invention relates to a pernasally administrable preparation for the controlled release of sexual hormones to the systemic circulation, in particular to a formulation which enables its active ingredient to be absorbed in a sustained manner providing a better bioavailability at very low doses and longer duration of action. |
US08574621B2 |
Adhesive patch for treatment of tinea unguium
The present invention provides an adhesive patch for the treatment of tinea unguium intended to be applied once a day, comprising terbinafine and/or a pharmacologically acceptable salt thereof in an amount of 3 mg/cm2, wherein the adhesive patch is used so that the terbinafine concentration in nails may be 295±127 ng/mg and the terbinafine concentration in plasma may be 23 pg/mL or less, 8 weeks after the start of application, per cm2 of the patch size. |
US08574620B2 |
Composite material for tissue repair
The present disclosure provides a biocompatible composite and method for its use in repairing tissue defects, including defects in cartilage. The biocompatible composite includes a fibrous polymeric component and a polymerizable agent, which is capable of forming the biocompatible composite in situ at the site of a tissue defect. In embodiments, the repair site at which the biocompatible composite is to be applied may be treated with a priming agent, permitting polymerization of the polymerizable agent to the tissue located at the repair site. |
US08574619B2 |
Reducing cholesterol levels with combined use of quercetin and statin
A method of reducing the cholesterol level of a subject by administering to that subject quercetin, vitamin C, vitamin B3, and statin. |
US08574618B2 |
Perforated bioabsorbable oil film and methods for making the same
A bio-absorbable stand-alone film is derived at least in part from fatty acids. The bio-absorbable stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. The stand-alone film has one or more perforations or depressions formed therein. Corresponding methods of making the bio-absorbable stand-alone film with one or more perforations or depressions include molding, cutting, carving, puncturing or otherwise suitable methods to create the perforations or depressions in the bio-absorbable stand-alone film. The resulting stand-alone film is bioabsorbable. |
US08574617B2 |
Implant pellets and method using same
A system comprising a plurality of implantable pellets, wherein one such implantable pellet delivers localized, controlled and sustained release of a predetermined quantity of one or more pain relief agents, in optional combination with one or more anti-inflammatory agents, one or more polymeric excipients, and/or one or more surfactants. An anesthetic/analgesic pellet is used in combination with one or more pharmaceutical pellets as part of a single procedure to provide desired a pharmaceutical to the animal while simultaneously alleviating pain and, optionally, inflammation at the injection site. |
US08574613B2 |
Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir including the effective agent, an impermeable tube which encloses portions of the reservoir, and a permeable member at an end of the tube. |
US08574611B2 |
Composite bone repair material
The present invention relates to a sliceable composite bone repair material comprising a porous block-shaped ceramic scaffold and a stabilizing polymer disposed therein. Said ceramic scaffold is a synthetic ceramic material or a naturally-derived material. Additionally said scaffold comprises interconnected macropores. |
US08574608B2 |
Bactericidal silver surfactant delivery into coating and polymer compositions
Disclosed are surfactant compounds and compositions that are antimicrobial. Also provided are polymeric compositions incorporating the surfactant compounds. The polymeric compositions may be used to form antibacterial coatings on surfaces. |
US08574605B2 |
Methods for the preparation of concentrated aqueous bromine solutions and high activity bromine-containing solids
The invention includes convenient methods of preparing: (1) highly concentrated liquid bromine-containing biocidal solutions, (2) highly concentrated mixed halogen liquid bromine and chlorine-containing biocidal solutions, and (3) high-activity bromine-containing biocidal solids, all having excellent physical and chemical stability. One method yields solutions that have concentrations of bromine in excess of 18% as Br2 (8% as Cl2) in which the mole ratio of hydroxide ion to hydrogen ion source is at least 1.9:1. Another method employs elemental bromine in conjunction with a solid organic or inorganic halogenating agent to yield halogen solutions at concentrations greater than 22.9% as Br2 (10.2% as Cl2). This method can be performed under conditions that exceed the solubility of the active ingredient such that it crystallizes and is recovered as a hydrated or anhydrous salt in good yield. |
US08574602B2 |
Stabilized cationic ammonium compounds for topical compositions
Stabilized cationic ammonium compounds are described. The compounds are stabilized with metal chelators that impede the generation of nitrogen comprising groups from the cationic ammonium compounds. |
US08574599B1 |
Methods and products for inducing mucosal immunity
The invention relates methods and products for inducing mucosal immunity. In particular, the invention relates to the use of immunostimulatory oligonucleotides containing a CpG motif for inducing mucosal immunity. The CpG immunostimulatory oligonucleotides may be administered alone or in combination with antigen and/or with other adjuvants. |
US08574587B2 |
Selective heated extraction of albumin proteins from intact freshwater algal cells
Methods for selective extraction and fractionation of algal proteins from an algal biomass or algal culture are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which allow for efficient separation of algal proteins. These proteins can be used as renewable sources of proteins for animal feedstocks and human food. Further, lipids remaining in the algal biomass after extraction of proteins can be used to generate renewable fuels. |
US08574585B2 |
KDR peptides and vaccines comprising the same
The present invention provides nonapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:2, 3, 5, 8, 11, or 12; nonapeptides or decapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO:29, 30, 33, 34, 40, or 46; and peptides with cytotoxic T cell inducibility, in which one, two, or several amino acids are substituted or added to the above-mentioned amino acid sequences, as well as pharmaceuticals for treating or preventing tumors, where the pharmaceuticals comprise these peptides. The peptides of this invention can be used as vaccines. |
US08574579B2 |
Anti-IL-23 antibodies
An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. |
US08574572B2 |
Method of treating pulmonary disease by administering an antibody to G-CSF receptor
The present invention relates generally to a method for treating or preventing or otherwise ameliorating the effects of pulmonary diseases characterized by or associated with infiltration of neutrophils and complications arising therefrom. The present invention further provides agents and pharmaceutical compositions comprising agents which inhibit the activity of G-CSF or its receptor, interfere with G-CSF signaling and/or which down-regulate expression of G-CSF or its receptor. |
US08574569B2 |
Stabilized protease composition
A composition is provided, which comprises a serine protease; a reversible inhibitor of said serine protease; and a stabilizing agent M having the formula I: Also provided are uses of the composition as a medicament, and other uses and methods employing its various properties. |
US08574567B2 |
Multipotent stem cells and uses thereof
The invention provides a quiescent stem cell having the capacity to differentiate into ectoderm, mesoderm and endoderm, and which does not express cell surface markers including MHC class I, MHC class II, CD44, CD45, CD13, CD34, CD49c, CD73, CD105 CD90, CD66A, CD66E, CXCR4, CD133 or an SSEA. The invention further provides a proliferative stem cell, which expresses genes including Oct-4, Nanog, Sox2, GDF3, P16INK4, BMI, Notch, HDAC4, TERT, Rex-1, TWIST, KLF-4 and Stella but does not express cell surface markers including MHC class I, MHC class II, CD44, CD45, CD13, CD34, CD49c, CD73, CD105, CD90, CD66A, CD66E, CXCR4, CD133 or an SSEA. The cells of the invention can be isolated from adult mammals, have embryonic cell characteristics, and can form embryoid bodies. Methods for obtaining the stem cells, as well as methods of treating diseases and differentiated the stem cells, are also provided. |
US08574564B2 |
Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
The application is related to compositions and methods for the treatment of hypersensitivity, wherein the compositions comprise a particle packaged with immunostimulatory nucleic acids. The compositions of the invention are particularly useful in the treatment of atopic eczema, asthma and IgE-mediated allergy (type I allergy), especially pollen allergy and house dust allergy. |
US08574563B2 |
Hepatitis C virus inhibitors
The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection. |
US08574560B2 |
Hair styling method
A hair styling method including: (A) increasing the number of intersections of hair fibers, thereby enhancing the volume of the hair; and (B) applying an aerosol hair cosmetic composition capable of forming a film having a film strength, as measured by a film strength evaluation method, of 800 gf/cm2 or greater. |
US08574557B2 |
Composition for a cosmetic and a cosmetic comprising the same
Present invention provides a composition for a cosmetic comprising a fluorine-containing silicone polymer having a three-dimensional, cross-linked structure, prepared by addition polymerizing the following (A), (B) and (C) and containing 10 to 30 mass % of the fluorine atoms, relative to a total mass of (A) to (C), (A) a vinyl group-containing organopolysiloxane represented by the following formula (1): (B) an organohydrogenpolysiloxane represented by the following formula (2): and (C) an organopolysiloxane having a reactive group on one end alone and represented by the following formula (3), and further comprising (D) a low viscosity silicone oil with a dynamic viscosity of 50 mm2/s or less at 25 degrees C. |
US08574554B2 |
Uses of 4-methyl-5-hydroxy-hexanoic acid lactone
The present invention relates to the use of 4-methyl-delta-hexylactone for imparting, modifying and/or intensifying one or more smell or flavor impressions from the group consisting of hay, coumarin, lactone and richness in the mouth. |
US08574553B2 |
Aerosol wax-effect styling compositions and methods for styling and shaping keratinous fibers
The present disclosure relates to a hair cosmetic composition comprising: at least one anionic fixing polymer, at least one polyol, at least one liquid fatty alcohol, at least one lower C1-C4 monoalcohol, and at least one propellant gas, comprising a water content of less than 10% by weight, with respect to the total weight of the composition, and wherein the hair cosmetic composition is packaged in an aerosol device. Also disclosed herein is a the use of this composition, as well as a method for styling and shaping the hair, such as providing hair with a styling effect. |
US08574550B2 |
Biocompatible polymeric contrast agents and radiopaque materials for medical services
In accordance with the present invention, a high intensity radiopaque contrast agent is disclosed. The agent may be coated on or incorporated within bulk materials, which may then be subsequently utilized to fabricate a radiopaque medical device. Primary effects through chemistry include higher radiopaque concentrations per unit weight of the radiopaque element or agent. Secondary effects include selective placement of the radiopaque elements which may further enhance the radiopacity of the device with reduced requirements of the radiopaque agent. Such a radiopaque contrast agent may be produced in various forms such as a dendrimer and/or incorporated as the end groups of polymeric chain. In addition one can incorporate biological and/or pharmaceutical agents in combination with the present invention. |
US08574549B2 |
Nanoparticle contrast agents for diagnostic imaging
Compositions of nanoparticles functionalized with at least one zwitterionic moiety, methods for making a plurality of nanoparticles, and methods of their use as diagnostic agents are provided. The nanoparticles have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle comprises a core, having a core surface essentially free of silica, and a shell attached to the core surface. The shell comprises at least one silane-functionalized zwitterionic moiety. |
US08574548B2 |
Antagonists of ligands and uses thereof
The invention provides multivalent ligand binding agents (traps) for members of the TGF-β superfamily and polypeptide linkers and methods for making and using such constructs. The traps may be used as therapeutic or diagnostic (imaging or non-imaging) agents for diseases/disorders caused by over-production/activity of the target ligand. In an embodiment of the invention there is provided a multivalent binding agent with affinity for a member of the TGF-β superfamily, the agent having the general structure I: ( |
US08574547B2 |
Photoacoustic probes and methods of imaging
Embodiments of the present disclosure provide for photoacoustic probes, methods of determining the presence and location of a specific target, methods of determining the presence and location of an enzyme, methods of determining the presence and location of a specific target and an enzyme, and the like. |
US08574544B1 |
Pharmaceutical composition of nanoparticles
The invention discloses a pharmaceutical composition of nanoparticles consisting of chitosan, a negatively charged substrate, and at least one bioactive agent that is encapsulated within cucurbiturils for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery. |
US08574543B2 |
Method of isotope labeling and determining protein synthesis, quantitation and protein expression
A method including isotope labeling of a newly synthesized protein in a sufficient quantity such that a newly synthesized protein spectra and the pre-existing protein spectra are sufficiently separated. A further method including determining a ratio of a new and a pre-existing protein from mass spectra obtained by using mass spectrometry. In this method a resultant spectrum may be presented as integrated peak heights for a corresponding mass to charge ratio in the “centroid” mode. |
US08574536B2 |
Method to produce light-emitting nano-particles of diamond
Method to produce diamonds containing Nitrogen-Vacancy centers from diamonds grown by a high pressure and high temperature process and containing isolated substitutional nitrogen, comprising: —Irradiating (12) said diamonds by an electron beam such that the irradiation dose is comprised between 1017 and 1019 electrons per square centimeter; —annealing (14) the irradiated diamonds in vacuum or in a inert atmosphere at a temperature above 700° C. and for at least 1 hour; characterized in that said electron beam has an acceleration energy above 7 MeV. |
US08574530B2 |
Process for producing hydrocyanic acid
The present invention relates to an improved process for producing hydrocyanic acid by reaction of ammonia with methane in which a small amount of at least one sulphur-containing compound corresponding to the general formula R S (S)x—R′ is added, in which R and R′, which are identical or different, represent a linear or branched alkyl or alkenyl radical containing from 1 to 5 carbon atoms, and x is a number ranging from 1 to 5, to the reactive gas mixture before it passes over the catalyst. The process according to the invention makes it possible to obtain improved yields of HCN. Another subject of the invention relates to the use of the resulting product for producing methionine, acetone cyanohydrin, adiponitrile or sodium cyanide. |
US08574527B2 |
Process for aftertreating carbon black
The invention relates to a process for aftertreating carbon black, wherein the carbon black is subjected to a carrier gas flow in a fluidized bed apparatus in the lower region of the apparatus, an additional gas stream is introduced into the fluidized bed apparatus, and the carbon black is aftertreated in the fluidized bed which arises. |
US08574525B2 |
Using boron-containing compounds, gasses and fluids during ammonothermal growth of group-III nitride crystals
Boron-containing compounds, gasses and fluids are used during ammonothermal growth of group-Ill nitride crystals. Boron-containing compounds are used as impurity getters during the ammonothermal growth of group-Ill nitride crystals. In addition, a boron-containing gas and/or supercritical fluid is used for enhanced solubility of group-Ill nitride into said fluid. |
US08574524B2 |
Porous composite oxide and production method thereof
The present invention provides a porous composite oxide comprising an aggregate of secondary particles in the form of aggregates of primary particles of a composite oxide containing two or more types of metal elements, and having mesopores having a pore diameter of 2-100 nm between the secondary particles; wherein, the percentage of the mesopores between the secondary particles having a diameter of 10 nm or more is 10% or more of the total mesopore volume after firing for 5 hours at 600° C. in an oxygen atmosphere. |
US08574523B2 |
Advanced dry head-end reprocessing of light water reactor spent nuclear fuel
A method for reprocessing spent nuclear fuel from a light water reactor includes the step of reacting spent nuclear fuel in a voloxidation vessel with an oxidizing gas having nitrogen dioxide and oxygen for a period sufficient to generate a solid oxidation product of the spent nuclear fuel. The reacting step includes the step of reacting, in a first zone of the voloxidation vessel, spent nuclear fuel with the oxidizing gas at a temperature ranging from 200-450° C. to form an oxidized reaction product, and regenerating nitrogen dioxide, in a second zone of the voloxidation vessel, by reacting oxidizing gas comprising nitrogen monoxide and oxygen at a temperature ranging from 0-80° C. The first zone and the second zone can be separate. A voloxidation system is also disclosed. |
US08574521B2 |
Gas stream purification apparatus and method
An apparatus and method for removing contaminants from a gas stream is provided which includes (a) introducing the gas stream into a reaction chamber of a scrubber; (b) oxidizing first contaminants in a liquid phase with a reactive species in a sump of the scrubber for providing an oxidizing solution; (c) oxidizing second contaminants in a gas phase of the gas stream above the sump with excess reactive species disengaging from the oxidizing solution in the sump; (d) oxidizing and scrubbing third contaminants in a gas-liquid contact assembly disposed above the gas stream. |
US08574511B2 |
Test instrument and optical measurement apparatus
It is an object to provide a test instrument and an optical measurement apparatus which enable easy matching of test results when tests by optical measurement are performed with respect to a large number of patients.To the above end, a test instrument B is provided, which includes reagent retaining portions 8A, 8B, 8C retaining a reagent which reacts with a sample to produce a color reaction. The test instrument B includes a patient information entry section 64 as an example of patient identifying information region in which patient identifying information is to be written. |
US08574508B2 |
Method of cooling a sterilizer
A method for cooling a jacketed autoclave or steam sterilizer by allowing a film of water to flow down as inner wall of the sterilizer's jacket. Condensate from the jacket space is drawn into a water ring pump. The water ring pump draws condensate from the lowest point of the jacket to a water side of the pump, and gas from the jacket to a normal suction inlet of the pump. During the process of cooling the sterilizer, a stream of water and air from the water ring pump is conducted to an upper part of the jacket of the steam sterilizer and is allowed to flow as a film down the inner wall of the jacket. Evaporation of the water is enhanced by lowering the pressure in the jacket. |
US08574505B2 |
Reactor and plant for the continuous preparation of high-purity silicon tetrachloride or high-purity germanium tetrachloride
A reactor and a plant containing the reactor for conducting a continuous, industrial process for preparing high-purity silicon tetrachloride or high-purity germanium tetrachloride is provided. The plant contains a plasma reactor having a dielectric, a high voltage electrode and an earthed, metallic heat exchanger, in which the longitudinal axes of the dielectric, of the high-voltage electrode and of the earthed, metallic heat exchanger are oriented parallel to one another and at the same time parallel to the force vector of gravity. |
US08574503B2 |
Instrument for nondestructively producing high-concentration hydrogen solution
An instrument for producing hydrogen-dissolved liquid comprises a hydrogen generating system stored in a separator, and the hydrogen generating system comprises: a hydrogen generating agent that reacts with raw water to generate hydrogen; a metal-ion sequestering agent that sequesters metal ions dissolved from the hydrogen generating agent; and a pH adjusting agent. |
US08574501B1 |
Natural gas to liquid fuels
A method and apparatus for converting natural gas from a source, such as a wellhead, pipeline, or a storage facility, into hydrocarbon liquid stable at room temperature, comprising a skid or trailer mounted portable gas to liquids reactor. The reactor includes a preprocessor which desulfurizes and dehydrates the natural gas, a first stage reactor which transforms the preprocessed natural gas into synthesis gas, and a liquid production unit using a Fischer-Tropsch or similar polymerization process. The hydrocarbon liquid may be stored in a portable tank for later transportation or further processed on site. |
US08574495B2 |
Apparatus for automatic analysis of samples on gel cards
The apparatus comprises a single transportable structure provided with several separate compartments located in a vertical stack within a cabinet, with means for the vertical transport of gel cards, means for the transport of units for moving the cards and pipetting probes, being displaceable to the entire transverse cross-section of the compartments in at least two of the vertical compartments or floors through moving along coordinate axes X, Y, Z at right-angles, and control means so that automatic functioning can take place simultaneously with manual actions to load and unload the necessary materials (samples, reagents, cards, wash solutions and waste solutions) in a random manner. |
US08574491B2 |
Unit and method for sterilizing a web of packaging material for a machine for packaging pourable food products
A unit for sterilizing a web of packaging material for a machine for packaging pourable food products includes a sterilizing chamber containing a liquid sterilizing agent at a first temperature; a conveying device for feeding the web through the sterilizing chamber before the web is formed into a succession of sealed packages of pourable food products; a hold tank for the sterilizing agent; a feed mechanism activated selectively to feed the sterilizing agent from the tank to the sterilizing chamber; a drain activated selectively to drain the sterilizing agent from the sterilizing chamber into the tank in the event of stoppage of the packaging machine; and a cooling device activated selectively, at the end of the package production cycle, to cool the sterilizing agent in the tank to a second temperature lower than the first temperature. |
US08574490B2 |
Methods and apparatus for reducing count of infectious agents in intravenous access systems
Methods and apparatus for preventing patient bloodstream infection by microorganisms during administration of various medications or fluids through IV lines. In particular, the invention reduces contamination of IV lines, connecters, stopcock valves, manifolds, ports, etc. by means of irradiation by violet and/or blue light. Each embodiment comprises a source of violet and/or blue light and an optical element optically coupled to that light source for shaping the radiation pattern of the light emitted by the light source. Preferably, a light-emitting diode or a laser diode that emits light in the desired wavelength can be used. The optical element, optically coupled to the light source, is embedded or installed in or attached to a component of an IV set, the emitted light being directed to a “point of entry” or any other stagnation point of an IV set. |
US08574488B2 |
Furnace refractory brick hearth tap hole
A method for accommodating increasing outward pressures in the tap holes of a hearth furnace includes configuring a tap hole lining and disposing it inside a hollow cylindrical conduit such that the tap hole lining can slide in response to outward pressures and growth in the hearth brick. The tap hole lining is retained inside the hollow cylindrical conduit with a retaining ring and spring assemblies. |
US08574484B2 |
RTM method and method for manufacturing fiber-reinforced resin molded body
Provided is a RTM method wherein a molding die composed of a temperature control mechanism, which is arranged on at least one of a plurality of dies that form a molding die and adjusts the temperature of the die, and a valve mechanism, which starts and stops supply of a resin in a state of having fluidity to the cavity of the molding die, is used. In the method, a plurality of the valve mechanisms are arranged on the molding die, each of the valve mechanisms is provided with one or a plurality of temperature control systems which adjust the temperature of the valve mechanism, the resin in the state of having fluidity is supplied to the cavity from the valve mechanisms, and a reinforcing fiber base material contained in the cavity is impregnated with the resin. |
US08574475B2 |
Process of and apparatus for making mineral fibers
The present invention relates to a method of making mineral fibers, comprising providing a circulating combustion chamber (1) which comprises a top section (2), a bottom section (3) and a base section (4), injecting primary fuel, particulate mineral material and primary combustion gas into the top section of the circulating combustion chamber and combusting the primary fuel thereby melting the particulate material to form a mineral melt and generating exhaust gases, separating the mineral melt from the exhaust gases wherein the exhaust gases pass through an outlet (8) in the circulating combustion chamber and the mineral melt collects in the base section of the circulating combustion chamber, injecting secondary fuel, which comprises liquid or gaseous fuel, and secondary combustion gas into the bottom section of the circulating combustion chamber to form a flame in the bottom section which heats the melt, and flowing a stream of the collected melt through an outlet (15) in the base section to a centrifugal fiberising apparatus and forming fibers. The present invention also provides an apparatus for use in the method of the invention. |
US08574471B2 |
System and method for forming concrete structures
One possible embodiment of the invention could be a system for creating forms used to make concrete structures comprising of plurality of panels, each panel having two or more sets of spaced-apart tie apertures; a plurality of ties, each tie forming a body between two ends, each end having a locking aperture, a plurality of L-shaped brackets with two flanges having a respective set of spaced-apart perforations; a plurality of locking mechanisms that attach to ties and connect L-shaped brackets together; wherein two or more ties are located between a pair of parallel and opposing panels, the ends of the ties protruding through respective tie apertures and perforations of L-shaped brackets located on the outside of the panels, the locking mechanisms engaging respective locking apertures to form an assembled pair of panels, the assembled pairs being connected together to create a form with a continuous cavity to receive plastic concrete. |
US08574465B2 |
Organic polymeric photon up-conversion nanoparticles for biological applications
The present invention relates to organic polymeric photon up-conversion nanoparticles for biological applications, such as labeling and/or detection of cells, biological (macro-) molecules or other analytes, as well as for sensing temperature, pressure, oxygen and other substances that influence the up-conversion process. It further relates to organic photon up-conversion nanoparticles for singlet oxygen generation and the treatment of diseases, such as cancer. |
US08574457B2 |
Mixture of liquid-crystal compounds, system of three liquid-crystal mixtures and their use
Three organic compounds mixtures of liquid-crystal properties, which when mixed together in a precisely determined weight ratio, may show an ability to form thermo-optically active mesophases of established, narrow range thermooptical transitions separation, every 0.5° C., in the temperature range: from 31.8° C. to 32.8° C., from 32.8° C. to 33.8° C., and from 33.8° C. to 34.8° C. and system including these mixtures. The use of these mixtures and the system containing the above mentioned mixtures for colorimetric detection of temperature differentiation on the surface of biological objects in a narrow range of temperatures. |
US08574451B2 |
Trans-chloro-3,3,3-trifluoropropene for use in chiller applications
The present invention relates to refrigerant compositions containing trans-chloro-3,3,3-trifluoropropene (1233zd(E)) useful for chiller applications and processes using 1233zd(E). |
US08574449B2 |
Method for manufacturing printed wiring board
Quickly making changes to etching conditions suppresses the production yield of printed wiring boards from being deteriorated. Disclosed is a method comprising: an etching step that comprises: preparing a conductor-clad base material continuous in a certain direction, the conductor-clad base material (1) having an insulating layer and one or more conductive layers formed on main surfaces of the insulating layer; and subjecting a predetermined region of a conductor layer of one main surface of the conductor-clad base material (1) to an etching process thereby to form a wiring pattern (1a) to be of a product and an inspection pattern (1b) to be used for inspection; a measuring step that measures a line width of the inspection pattern after the etching step; and a control step that controls an etching condition in the etching step based on the measured line width. |
US08574448B2 |
Plasma generation method, cleaning method, and substrate processing method
A plasma generation method in a toroidal plasma generator that includes a gas passage having a gas entrance and a gas outlet and forming a circuitous path and a coil wound around a part of the gas passage includes the steps of supplying a mixed gas of an Ar gas and an NF3 gas containing at least 5% of NF3 and igniting plasma by driving the coil with a high-frequency power, wherein the plasma ignition step is conducted under a total pressure of 6.65-66.5 Pa. |
US08574432B2 |
Integrated chromatography devices and systems for monitoring analytes in real time and methods for manufacturing the same
Systems and methods for monitoring analytes in real time using integrated chromatography systems and devices. Integrated microfluidic liquid chromatography devices and systems include multiple separation columns integrated into a single substrate. Using such a device, parallel analysis of multiple samples can be performed simultaneously and/or sequential analysis of a single sample can be performed simultaneously on a single chip or substrate. The devices and systems are well suited for use in high pressure liquid chromatography (HPLC) applications. HPLC chips and devices including embedded parylene channels can be fabricated using a single mask process. |
US08574428B2 |
Desulfurization of petroleum streams using metallic sodium
In some embodiments, the invention is a method of removing sulfur from a hydrocarbon feed using the steps of dissolving metallic sodium in a first solvent, combining the sodium/first solvent solution with a sulfur-free alkane or cycloalkane second solvent, vaporizing the first solvent from sodium/first solvent/second solvent combination to transfer the dissolved metallic sodium into the second solvent, and then combine the resultant liquid with a liquid hydrocarbon feed containing an organosulfur species. The resulting stream is combined with a hydrogen donor. The combination is heated and pressurized to form a liquid hydrocarbon product containing sodium sulfide. The liquid hydrocarbon product containing sodium sulfide is then cooled, and the sodium sulfide is extracted. The extracted sodium sulfide is then processed in a sodium sulfur cell to regenerate the sodium and recycle it to the feed. |
US08574427B2 |
Process for removing refractory nitrogen compounds from vacuum gas oil
A process for removing a refractory nitrogen compound from a hydroprocessed vacuum gas oil feed includes contacting the hydroprocessed vacuum gas oil feed comprising the nitrogen compound with a VGO-immiscible phosphonium ionic liquid to produce a hydroprocessed vacuum gas oil and VGO-immiscible phosphonium ionic liquid mixture, and separating the mixture to produce a hydroprocessed vacuum gas oil effluent having a reduced refractory nitrogen compound content relative to the vacuum gas oil feed. |
US08574425B2 |
Process for removing heavy polynuclear aromatic compounds from a hydroprocessed stream
The present invention is an improved process for stripping HPNA's from hydroprocessed streams in a fractionation column having a split shell configuration. Only one vapor stripping feed is required to the split shell of the fractionation column. The resulting reduction in steam requirement provides a superior fractionation in the column. |
US08574423B2 |
Biosensor, biosensor chip and biosensor device
A biosensor includes a working electrode 101, a counter electrode 102 opposing the working electrode 101, a working electrode terminal 103 and a working electrode reference terminal 10 connected to the working electrode 101 by wires, and a counter electrode terminal 104 connected to the counter electrode 102 by a wire. By employing a structure with at least three electrodes, it is possible to assay a target substance without being influenced by the line resistance on the working electrode side. |
US08574421B2 |
Water splitting apparatus and method of using the same
A water-splitting apparatus and method generating hydrogen and oxygen at separate electrodes have a structure enabling a photo catalytic reaction to be efficiently performed. The apparatus includes a photolysis element having an N-type water-splitting electrode surface and a P-type water-splitting electrode surface at the opposite side surface to the N-type water-splitting electrode surface, a hydrogen generating cell holding the N-type water-splitting electrode surface and collecting the hydrogen generated at that water-splitting electrode surface, and an oxygen generating cell holding the P-type water-splitting electrode surface, collecting the oxygen generated at that water-splitting electrode surface, and adjoining the hydrogen generating cell across the photolysis element. The photolysis element has through holes enabling circulation of water between the hydrogen and oxygen generating cells. The through holes are arranged so that light irradiated on one of the N-type and P-type water-splitting electrode surfaces does not pass through to the opposite side water-splitting electrode surface. |
US08574412B2 |
Magnet mounting system and magnetron sputtering device having same
A magnetron sputtering device includes a main body and a magnet mounting system for receiving magnets. The magnet mounting system comprises a first annular member, a second annular member coaxially encasing the first member, a third annular member coaxially encasing the second member, a first driving device connected to the first annular member, a second driving device connected to the second annular member, and a third driving device connected to the third annular member. The first driving device, the second driving device, and the third driving device are respectively configured for driving the first annular member, the second annular member, and the third annular member to move along an axis of the first annular member. |
US08574411B2 |
Reactive sputtering chamber with gas distribution tubes
A sputtering apparatus for processing large area substrates is provided. By introducing gas across the entire target surface, a uniform composition film may be formed on the substrate. When the gas is introduced merely at the perimeter, the gas distribution is not uniform. By providing a gas introduction tube across the processing area, the reactive gas will uniformly distribute to the whole target. Also, providing the gas tube with multiple inner tubes provides a quick, effective gas dispersion capability. |
US08574410B2 |
Method and apparatus for improved high power impulse magnetron sputtering
A high power impulse magnetron sputtering apparatus and method using a vacuum chamber with a magnetron target and a substrate positioned in the vacuum chamber. A field coil being positioned between the magnetron target and substrate, and a pulsed power supply and/or a coil bias power supply connected to the field coil. The pulsed power supply connected to the field coil, and the pulsed power supply outputting power pulse widths of greater that 100 μs. |
US08574405B1 |
System for conveying biomass
A system is described for processing biomass through a pyrolysis chamber that utilizes revolving polygon platforms, a conveyor system, and an airlock for introducing or removing biomass into the pyrolysis chamber. Biomass can be introduced via a first revolving polygon platform, and biochar resulting from pyrolysis can be removed via a second revolving polygon platform. |
US08574400B1 |
Tissue comprising macroalgae
The disclosure provides tissue webs, and products incorporating the same, where the webs comprise macroalgae fibers. More specifically the disclosure provides soft and durable tissue webs comprising at least about 1 percent macroalgae fiber by weight of the web. In the tissue webs of the present disclosure, macroalgae fibers may preferably replace high average fiber length wood fibers, which increases the strength and durability of the web without negatively stiffness. |
US08574397B2 |
Bevel edge plasma chamber with top and bottom edge electrodes
A plasma processing chamber configured for cleaning a bevel edge of a substrate is provided. The chamber includes a top edge electrode surrounding an insulating plate, and the insulator plate opposes a bottom electrode. The top edge electrode is electrically grounded and separated from the insulator plate by a top dielectric ring. The chamber also includes a bottom edge electrode that is electrically grounded and surrounds the bottom electrode and is separated from the bottom electrode by a bottom dielectric ring. The bottom edge electrode is oriented to oppose the top edge electrode, and the bottom edge electrode has an L shape that is up-facing. Bevel edge plasma processing of a substrate edge is configured to be processed in a chamber having the top and bottom edge electrodes. |
US08574395B2 |
Protection sheet for coating film
Provided is a protective sheet for a coating layer comprising a substrate sheet and provided thereon a pressure-sensitive adhesive layer, which can be applied as well to a coated surface insufficiently cured immediately after dried, and the pressure-sensitive adhesive layer described above comprises an addition reaction type silicone-based pressure-sensitive adhesive. |
US08574393B2 |
Method for making touch panel
An exemplary method for making a touch panel includes the steps of: providing a flexible substrate; fabricating a carbon nanotube film; laying the carbon nanotube film to form a carbon nanotube layer stacked on the flexible substrate; heat-pressing the carbon nanotube layer of the flexible substrate; and separately forming at least two electrodes on a surface of the carbon nanotube layer, thereby forming the touch panel. |
US08574390B2 |
Apparatus for making bag assembly
A method of forming a bag assembly by RF welding includes generating from a single source of RF energy a high frequency electric field having a first strength between tube-welding electrodes of opposing die members and a second strength less than said first strength between perimeter-welding electrodes of the opposing die members. Subjecting a tube assembly and corresponding portions of sheets surrounding the tube assembly to the high frequency electric field of said first strength for a predetermined amount of time to weld the sheets to a tube along a tube-weld. Corresponding portions of the sheets between the perimeter-welding electrodes are subjected to the high frequency electric field of said second strength for said predetermined amount of time to weld the sheets together along a bladder perimeter-weld. The subjecting steps are performed simultaneously so that the bag assembly is formed in one welding operation. |
US08574389B2 |
Method of manufacturing thin film device
A method of manufacturing a thin film device according to an aspect of the invention may include: preparing a substrate on which a sacrificial layer and a thin film to be transferred are sequentially formed; temporarily bonding the thin film to a circumferential surface of the transfer roll, and simultaneously removing the sacrificial layer to separate the thin film from the substrate at a first position of a transfer roll that is rolling; and transferring the thin film onto a sheet by running the sheet so that a surface of the sheet is bonded to the thin film temporarily bonded to the circumferential surface of the transfer roll.The substrate may be a transparent substrate. |
US08574381B2 |
Weld metal and welded structure having weld joints using the same
To provide weld metal that has a high strength and toughness in the as-welded condition or in the annealed condition. The weld metal of the present invention contains by weight %, C: 0.04-0.15%, Si: 0.50% or less, Mn: 1.0-1.9%, Ni: 1.0-4.0%, Cr: 0.10-1.0%, Mo: 0.20 to 1.2%, Ti: 0.010-0.060%, Al: 0.030% or less, O: 0.15-0.060%, N: 0.010% or less, Fe and inevitable impurities as the remaining contents. The weld metal is further characterized by the fact that the ratio of Ti content (%) to Si content (%) i.e., [compound type Ti]/[compound type Si] is more than 1.5, and the number A defined by the following formula is 0.50 or more, wherein A=[Ti]/([O]−1.1×[Al]+0.05×[Si]). |
US08574374B2 |
Formulations, their use as or for producing dishwashing compositions and their preparation
Formulations comprising (A) at least one compound selected from aminocarboxylates and polyaminocarboxylates, and salts and derivatives thereof, (B) at least one zinc salt, and (C) at least one homopolymer or copolymer of ethyleneimine. |
US08574371B2 |
Method for cleaning containers and cleaning machine
A method for cleaning containers, in particular bottles of glass or plastics, and a cleaning machine with at least one cleaning medium, with the containers cleaned at least in one station preferential for the cleaning result and/or in a procedure step with at least essentially chemical-free cleaning media. The cleaning medium is advantageously a granular material, in particular granular ice, carried under pressure with compressed air or compressed water. The cleaning machine suited for carrying out the method includes downstream of an unpacking and presoaking station, a pre-cleaning station with a high pressure water blasting pre-cleaning section, and subsequently an intensive cleaning station with at least one intensive cleaning section to which a pressure blasting system for chemical-free, granular material and a carrier medium are associated, and a disinfection station following the intensive cleaning station. |
US08574369B2 |
Method of removing resist and apparatus therefor
A method for removing a resist on a substrate includes supplying unsaturated hydrocarbon gas or fluorine substitution product gas of unsaturated hydrocarbon, at a lower pressure than an atmospheric pressure, to a system of reaction capable of heating the substrate and supplying ozone gas at a lower pressure than the atmospheric pressure to the system of reaction. The ozone gas is an ultra-high concentration ozone gas obtained by separating only ozone from ozone-containing gas by a difference of vapor pressure through liquefaction separation and by vaporizing a liquefaction-separated ozone again. The substrate may be cleaned with pure water. A susceptor that holds the substrate is provided in a chamber of the system of reaction and is heated by a light source that emits infrared light. An internal pressure of the chamber is controlled so that a temperature of the substrate is 90° C. or less. |
US08574364B2 |
GaN-crystal free-standing substrate and method for producing the same
The invention relates to a GaN-crystal free-standing substrate obtained from a GaN crystal grown by HVPE with a (0001) plane serving as a crystal growth plane and at least one plane of a {10-11} plane and a {11-22} plane serving as a crystal growth plane that constitutes a facet crystal region, except for the side surface of the crystal, wherein the (0001)-plane-growth crystal region has a carbon concentration of 5×1016 atoms/cm3 or less, a silicon concentration of 5×1017 atoms/cm3 or more and 2×1018 atoms/cm3 or less, and an oxygen concentration of 1×1017 atoms/cm3 or less; and the facet crystal region has a carbon concentration of 3×1016 atoms/cm3 or less, a silicon concentration of 5×1017 atoms/cm3 or less, and an oxygen concentration of 5×1017 atoms/cm3 or more and 5×1018 atoms/cm3 or less. |
US08574359B2 |
High performance sulfo-aluminous clinker
The invention relates to a sulfo-aluminous clinker with optimal setting time and short term compressive strengths, comprising a mixture of the following phases: —calcium sulfoaluminate, or C4A3$, in amounts higher than 50% by weight of the mixture, —belite, or C25, in amounts between 2 and 23%, —3C25 3C$ CaX2, X being fluorine or chlorine, between 3 and 15% —C11A7CaX2, X being fluorine or chlorine, between 2 and 12%, both fluorine and chlorine being altogether present in the mixture, and phase C5S2$ being absent. The invention also relates to a method for preparing this sulfo-aluminous clinker, and hydraulic binders comprising this clinker. |
US08574357B2 |
Water resistant aluminum pigment dispersion, aqueous ink composition containing the same, and method for manufacturing water resistant aluminum pigment dispersion
A water resistant aluminum pigment dispersion includes a water resistant aluminum pigment which is an aluminum pigment covered with a silica film, wherein the water resistant aluminum pigment is formed of an aluminum pigment having an average thickness from 5 nm to 30 nm and a covering film which contains Si and is formed on the surface of the aluminum pigment; and wherein the coverage ratio of the surface of the aluminum pigment by the covering film, calculated from the composition ratio of C, O, Al, and Si detected by XPS measurement at an incident angle of 30°, is in a range from 30% to 90%. |
US08574356B2 |
Ink composition and recording method
An ink composition includes an aluminum pigment, a white pigment, and a dispersion solvent, wherein the ink composition has a structure in which the aluminum pigment is dispersed in the dispersion solvent and the content of the white pigment is 0.01% to 10% based on the content of the aluminum pigment, or includes silver particles, a white pigment, and water, wherein the particle diameter d90 in the particle diameter accumulation curve of the silver particles is 50 nm to 1 μm, the ink composition has a structure in which the silver particles are dispersed in the water, and the content of the white pigment is 1% to 10% based on the content of the silver particles. |
US08574354B2 |
Reducing the carbon emissions intensity of a fuel
Techniques for reducing a carbon emissions intensity of a fuel includes injecting a carbon dioxide fluid into a first wellbore; producing a hydrocarbon fluid from a second wellbore to a terranean surface; and producing a fuel from the produced hydrocarbon fluid, the fuel including a low-carbon fuel and assigned an emissions credit based on a source of the carbon dioxide fluid. |
US08574349B2 |
Method for the removal of mercury from a stream of flue gas obtained from the combustion of coal
A method for the removal of mercury from a stream of flue gas obtained from the combustion of at least one coal type having an ASTM D388 coal rank of <3 includes the steps of introducing a kaolin or metakaolin-containing sorbent into the stream of flue gas and contacting the mercury with the kaolin or metakaolin-containing sorbent at a point where both the kaolin or metakaolin-containing sorbent and active free silica are present in the stream. The temperature of the flue gas is at least 900° C. The active free silica content of the flue gas resulting from the combustion of the coal is supplemented by the introduction of added active free silica such that the weight percentage of the total amount of active free silica relative to the weight of kaolin or metakaolin is at least 10%, the weight of any kaolin being expressed as the weight of metakaolin. |
US08574341B2 |
Method for recycling metals from waste tungsten catalysts
A method for recycling metals from waste tungsten catalysts comprises steps of: leaching, by soaking a waste tungsten catalysts into a highly oxidized acid and conducting a reaction between sulfur of the waste tungsten catalysts and the acid to obtain sulfide and oxidized acidic groups, wherein metals in the waste tungsten catalysts are dissolved and oxidized by the acid to obtain a first solution and dregs; and refining, by extracting metals of the waste tungsten catalysts from the first solution; wherein, the oxidized acidic groups obtained from the step of leaching is converted into highly oxidized acid, which is capable of being recycled. |
US08574336B2 |
Ultrasonic degassing of molten metals
Ultrasonic devices having an integrated purging gas delivery system are described, and such devices can be used to remove dissolved gasses and impurities from molten metals. |
US08574335B2 |
Holding sealing material, exhaust gas purifying apparatus, and method of manufacturing exhaust gas purifying apparatus
A holding sealing material includes inorganic fibers, a mat shape, a first end face and a second end face and a penetration portion. The mat shape has a width direction, a length direction and a thickness direction. The first end face and the second end face are each provided approximately in parallel with the width direction. The penetration portion penetrates the holding sealing material in the thickness direction. |
US08574333B2 |
Method of forming filter arrangements; and, apparatus
In one aspect a method of forming filter cartridge arrangements for use in air cleaners is provided. The method involves coiling a media pack with a central winding bead and cutting through the winding bead in the coiled media pack to form two media packs. An example filter arrangement is disclosed. In another aspect, a filter cartridge arrangement for use in air cleaners is provided. The filter cartridge arrangement includes a media pack including a plurality of inlet flutes and outlet flutes extending between first and second opposite flow faces and formed from an arrangement of facing sheet secured to corrugated sheet. An example cartridge includes a preform secured to the media pack. |
US08574331B2 |
Air-treatment mask systems, and related methods and air-treatment masks
Embodiments disclosed herein include air-treatment mask systems having at least one controllable air-treatment device that is controlled responsive to one or more signals from at least one pollutant sensor, and related methods of operation and air-treatment masks. In an embodiment, an air-treatment mask system includes a wearable air-treatment mask having a mask body including a face-securing member, and at least one controllable air-treatment device supported by the mask body. The air-treatment device is configured to treat incoming air. The system includes at least one pollutant sensor configured to sense ambient air for a presence of at least one pollutant and output one or more signals responsive to the sensing. The system includes control electrical circuitry operably coupled to the air-treatment device and the pollutant sensor and configured to control operation of the controllable air-treatment device responsive to receiving the signal(s) from the pollutant sensor. |
US08574330B2 |
Chemical mechanical polishing aqueous dispersion and chemical mechanical polishing method for semiconductor device
A chemical mechanical polishing aqueous dispersion of the invention includes (A) a first water-soluble polymer having a weight average molecular weight of 500,000 to 2,000,000 and including a heterocyclic ring in its molecule, (B) a second water-soluble polymer or its salt having a weight average molecular weight of 1000 to 10,000 and including one group selected from a carboxyl group and a sulfonic group, (C) an oxidizing agent, and (D) abrasive grains, and has a pH of 7 to 12. |
US08574327B2 |
Molten metal reactors
A molten metal reactor for converting a carbon material and steam into a gas comprising hydrogen, carbon monoxide, and carbon dioxide is disclosed. The reactor includes an interior crucible having a portion contained within an exterior crucible. The interior crucible includes an inlet and an outlet; the outlet leads to the exterior crucible and may comprise a diffuser. The exterior crucible may contain a molten alkaline metal compound. Contained between the exterior crucible and the interior crucible is at least one baffle. |
US08574325B2 |
System and method for processing material to generate syngas
The present invention is directed to system and method for processing material to generate syngas. A reactor chamber is implemented with a plurality of electrodes that can generate an arc within the chamber when electricity is applied to them. The arc can be used to create free radicals which along with the heat and light of the arc breakdown material comprising carbonaceous material, such as Municipal Solid Waste (MSW), into gas components that form syngas. The syngas can be extracted from the reactor chamber and be used for various commercial purposes. The reactor chamber may comprise a material feed system operable to move material from a material input opening in the reactor chamber towards the electrodes at a controlled rate. Further, the reactor chamber may comprise a water injection system within the reactor chamber operable to inject water into the reactor chamber while electricity is applied to the electrodes. Yet further, the reactor chamber may comprise a gas removal system within the reactor chamber operable to extract gas generated from breakdown of the material from a plurality of gas removal locations. The gas removal system may be integrated within the material feed system. |
US08574324B2 |
Reducing sulfur gas emissions resulting from the burning of carbonaceous fuels
A process for burning coal or other carbonaceous fuels captures sulfur and other undesirable compounds are captured and retained in non-reactive ceramic-like form after the combustion phase. The process involves addition of multiple element alkali powders and/or sorbents preferably containing oxidizing anions such as nitrates and nitrites, preferably based on calcium. In various embodiments, the remediation materials when applied in a complex powder and/or liquid containing multiple elements, result in higher sulfur capture than the materials would otherwise achieve on an individual basis. In a preferred embodiment, the sorbents contain elements that minimize or lower the melting point of the ash. This leads to lowered cohesiveness and toughness of the ash so that less ash builds up on the boiler and better heat transfer is obtained. |
US08574322B2 |
Propellant compositions and methods of making and using the same
Formulated propellants and methods of forming the same are described herein. The formulated propellants include a hydrocarbon fluid, wherein the formulated propellant exhibits a distillation curve 10% point at a temperature between 365° F. (185° C.) and 410° F. (210° C.) and an end point at or below 525° F. (273° C.). |
US08574321B2 |
Battery assembly method comprising a separate battery connector and a flex circuit for use in an electronic device
A battery assembly for use in an electronic device. The battery assembly may include a battery cell, a battery connector for providing power from the battery cell to the electronic device, and a flex circuit electrically coupling the battery cell to the electronic device. The battery connector may be located adjacent the battery cell, and may include one or more alignment mechanisms so that conductive pads connector align properly with corresponding conductive elements of the electronic device. The battery cell may be fixed to the electronic device using an adhesive layer placed between the cell and the electronic device. A tab may extend beyond the periphery of the battery cell to allow a user to pull or peal the battery cell from the electronic device for replacement or repair. |
US08574319B2 |
Solid electrolytic capacitor and method of manufacturing the same
A solid electrolytic capacitor is provided that includes a capacitor element having a dielectric coating, a solid electrolyte, and a cathode lead portion formed in order on a surface of an anode portion having an anode lead portion. The cathode lead portion is electrically connected to a cathode terminal by a connecting portion, and the connecting portion is formed of a sintered body of a metal. |
US08574318B2 |
Preparation method of optical colorful polyester film using microwave technique
A process for preparing an optical colored polyester film using microwave technique comprises the following steps: microwave dyeing treatment by passing a polyester film through a disperse dye suspension with a steady water phase in a dye-pool comprising a microwave generator; rinsing with water; rinsing with solvent; finally drying treatment, and then uniform optical colored films with various colors are obtained. The optical colored films are used as optical filters or optical protection films and as glass window films for automobile, and domestic and office windows. |
US08574317B2 |
Aqueous colouring composition
The present invention is related to an aqueous oxidative colouring composition for keratin fibres, especially human hair. The present invention is on an aqueous composition for colouring keratin fibres especially human hair comprising at least one hair dye, at least one oxidizing agent and at least one dispersed particles of a water insoluble polymer. Furthermore, the present invention is on a two part aqueous dyeing composition, wherein the two parts are mixed prior to application onto keratin fibres especially human hair wherein the aqueous first part comprises at least one hair dye and the aqueous second part comprises at least one oxidizing agent and at least one dispersed particles of a water insoluble polymer. |
US08574315B2 |
Electrospun structures and methods for forming and using same
The present invention relates to structures that contain one or more fiber and/or nanofiber structures where such structures can be formed on a wide variety of structures or surfaces (e.g., asperities, flat surfaces, angled surface, hierarchical structures, etc.). In one embodiment, the present invention relates to a process for forming one or more fibers, nanofibers or structures made therefrom on a wide variety of structures or surfaces (e.g., asperities, flat surfaces, angled surface, hierarchical structures, etc.). In another embodiment, the present invention relates to a process for forming one or more fibers, nanofibers or structures made therefrom on a wide variety of structures or surfaces (e.g., asperities, flat surfaces, angled surface, hierarchical structures, etc.) where such fibers and/or structures are designed to sequester, carry and/or encapsulate one or more substances. In still another embodiment, the present invention relates to structures that contain one or more fiber and/or nanofiber structures on asperities where the nanofiber and/or fiber structures are designed to sequester, carry and/or encapsulate one or more substances. |
US08574314B2 |
Resilient prosthetic and orthotic components which incorporate a plurality of sagittally oriented struts
A method of making a resilient prosthetic/orthotic component, particularly a shank for a lower extremity prosthesis in which the shank includes multiple sections which are unbounded in one or more portions of each other, and wherein the shank sections incorporate at least one voids and inserted materials between one or more shank sections to enhance shank flexibility while reducing stresses which can cause premature failure. |
US08574313B2 |
Metatarsal joint shape for prosthetic foot and control mechanism and system for same
A prosthetic foot can include a plate-like foot member extending along a longitudinal axis between an anterior end generally corresponding to a toe portion of a foot to a posterior end, and a metatarsal hinge comprising an elongate groove extending between medial and lateral edges of the foot member. The elongate groove can intersect the longitudinal axis of the foot member, and can be positioned along the length of the foot member at a location generally corresponding to a metatarsal region of the foot. The metatarsal hinge can also comprise a plurality of elongate apertures that extend completely through the foot member, or a plurality of recessed channels that extend only partially through the foot member, or a combination thereof. |
US08574309B2 |
Two-stage system and method for oxygenating and removing carbon dioxide from a physiological fluid
A two-stage system for oxygenating and removing carbon dioxide from a physiological fluid, including: a primary exchange module configured to receive a gas having oxygen therein and a carrier fluid having carbon dioxide therein. The primary exchange module is configured to transfer oxygen from the gas to the carrier fluid and transfer carbon dioxide from the carrier fluid to the gas to create an oxygen loaded carrier fluid and a carbon dioxide load gas. A secondary exchange module is configured to receive the oxygen loaded carrier fluid and a physiological fluid having the carbon dioxide therein. The secondary exchange module is configured to transfer the oxygen from the oxygen loaded carrier fluid to the physiological fluid and transfer carbon dioxide from the physiological fluid to the carrier fluid to create an oxygen loaded physiological fluid. |
US08574306B2 |
Acetabular cup
A method for placing a prosthetic acetabular cup within an acetabulum comprises implanting an acetabular cup with an eccentric socket. The acetabular cup may be substantially hemispherical with a cup rim and a portion of the cup rim removed defining a relief. The cup may accommodate a concentric liner in an eccentric position. Screw apertures may be present on the periphery of the cup and the screw trajectories may converge toward the dome of the cup. The cup is attached to a tool which is offset relative to the cup because of the substantially eccentric socket. The relief, when the cup is secured to the acetabulum, is positioned substantially anterior and the socket is positioned more posterior to provide a more natural center of rotation of a femoral head within the socket. The first relief reduces impingement of the acetabular cup on soft tissue. |
US08574304B2 |
Asymmetric tibial components for a knee prosthesis
An orthopaedic tibial prosthesis includes a tibial baseplate with an asymmetric periphery which promotes proper positioning and orientation on a resected tibia, while also facilitating enhanced kinematics, soft-tissue interaction, and long-term fixation of the complete knee prosthesis. The asymmetric baseplate periphery is sized and shaped to substantially match portions of the periphery of a typical resected proximal tibial surface, such that proper location and orientation is evident by resting the baseplate on the tibia. The baseplate periphery provides strategically positioned relief and/or clearance between the baseplate periphery and bone periphery, such as in the posterior-medial portion to prevent deep-flexion component impingement, and in the anterior-lateral portion to avoid undue interaction between the anatomic iliotibial band and prosthesis components. |
US08574303B2 |
Osteoarthritis treatment and device
A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container. |
US08574300B2 |
Expandable interbody spacer device
An expandable interbody spacer (10) is provided that includes a pair of oppositely facing endplate components (20, 40) and an interior component that includes one or more vertically extending stacks of arranged C-clip members (70) radially surrounding one or more bosses (30) protruding interiorly from one of the endplates, wherein the size and configuration of the bosses and the c-clip members are designed to allow the incremental expansion of expandable interbody spacer. |
US08574297B2 |
Intervertebral device having expandable endplates
An intervertebral implant having an endplate that can be slidably expanded following its placement in the intervertebral space. |
US08574296B2 |
Dual tendon bundle
The present invention relates generally to methods for preparing a dual tendon bundle that is useful as a replacement ligament or tendon graft for, for example, anterior cruciate ligament (ACL) reconstruction. More particularly, the dual tendon bundle prepared according to the present invention has a functional cross section diameter and/or a minimum length that meets or exceeds the standard requirements for replacement ligament or tendon grafts. The present invention further relates to the dual tendon bundle prepared by the disclosed methods and packages comprising the same. Methods of using the dual tendon bundle prepared according to the present invention by providing the dual tendon bundle thus obtained for implanting into a patient in need thereof are also provided. |
US08574292B2 |
Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate
Disclosed are soft, high refractive index, acrylic device materials. The materials contain a functionalized alkylphenol ethoxylate to reduce glistenings. |
US08574290B2 |
Mitral valve ring for treatment of mitral valve regurgitation
An active bodily ring having a housing adapted to be sutured to a bodily component and a loop disposed in the housing, the loop capable of actively expanding and compressing during the bodily components normal function. The housing defines a first chamber and a second chamber, the first chamber containing the loop and the second chamber providing a region capable of being sutured to the bodily component. In one embodiment, the housing can be a crimped-fabric housing. In another embodiment, the housing can be a woven-fabric housing having elastic properties. The housing can be made from polyester. |
US08574285B2 |
Intraluminal device with improved tapered beams
A strut, or beam, is provided for intraluminal devices. Strain which is introduced into a stent or other intraluminal device is distributed more evenly along the length of the improved strut by maintaining a substantially constant strain level along the length of an end portion. This may increase fatigue life or improve the performance of devices using the improved strut. The strain along the length of the end portion may be maintained substantially constant by varying a section property of the strut, including the width, thickness, cross-sectional area, material property or other characteristic of the end portion. |
US08574282B2 |
Apparatus and methods for delivery of braided prostheses
Blood vessels and other body lumens are expanded using an evertible braided prosthesis. The braided prosthesis is delivered to the blood vessel in a radially collapsed configuration. A leading edge of the braided prosthesis is then everted so that it expands as it is advanced through the blood vessel. Optionally, the prosthesis can be provided with a biologically active substance in order to inhibit hyperplasia or have other desired biological effects. |
US08574279B2 |
Methods for treating psychiatric disorders using light energy
Methods for treating psychiatric disorders using light energy are disclosed herein. A method for treating psychiatric disorders using light energy includes determining which hemisphere of the brain requires treatment using lateral visual field stimulation (LVFS) and applying light energy to the hemisphere of the brain to treat the psychiatric disorder other than depression. In an embodiment, light energy may include near infrared light (NIR). The methods of the present disclosure may be used to treat a variety of psychiatric disorders. In an embodiment, the methods may be used to treat a psychiatric disorder co-morbid with depression. |
US08574278B2 |
Wound care method and system with one or both of vacuum-light therapy and thermally augmented oxygenation
A combination therapy pad that includes a first layer and a second layer operatively coupled to the first layer. A fiber-optic array is disposed between the first layer and the second layer. A third layer is operatively coupled to the first layer. The third layer includes a vacuum tube in fluid communication with a vacuum source and a therapeutic fluid tube in fluid communication with a therapeutic fluid source. The third layer provides at least one of vacuum therapy and therapeutic fluid treatment to a wound area. |
US08574277B2 |
Eye therapy
Embodiments apply a cross-linking agent to a region of corneal tissue. The cross-linking agent improves the ability of the corneal tissue to resist undesired structural changes. For example, the cross-linking agent may be Riboflavin or Rose Bengal, and the initiating element may be photoactivating light, such as ultraviolet (UV) light. In these embodiments, the photoactivating light initiates cross-linking activity by irradiating the applied cross-linking agent to release reactive oxygen radicals in the corneal tissue. The cross-linking agent acts as a sensitizer to convert O2 into singlet oxygen which causes cross-linking within the corneal tissue. The rate of cross-linking in the cornea is related to the concentration of O2 present when the cross-linking agent is irradiated with photoactivating light. Accordingly, the embodiments control the concentration of O2 during irradiation to increase or decrease the rate of cross-linking and achieve a desired amount of cross-linking. |
US08574273B2 |
Bone screws and methods of use thereof
The invention features bone screws having a threaded screw body and a screw head attached to one end of the screw body, the bone screw further including: a) an interior channel extending longitudinally through the screw head and through at least a portion of the screw body, wherein the interior channel has a width of less than 5.0 millimeters; and b) a plurality of radially-disposed delivery channels connecting the interior channel to the exterior of the screw body, each delivery channel having exterior openings. The invention further features devices that include a bone screw and a delivery manifold detachably attached to the screw head of the bone screw. In addition, the invention features methods of treating a patient having a bone defect by using a bone screw described herein. |
US08574272B2 |
Semi-constrained screw and spinal plate assembly
A semi-constrained screw and a cervical plate assembly that engages to a cervical area of the human vertebrae system are disclosed. The semi-constrained screw and cervical plate assembly includes a cervical plate and one or more semi-constrained bone screws. Each semi-constrained bone screw includes an elongated shank, which is mechanically and releasably coupled to a head portion. The head portion includes one or more threaded segments which define one or more slits therebetween. As the semi-constrained bone screw is driven through the screw opening in the cervical plate and into the bone, the head portion allows poly-axial movement of the shank relative to the head portion. |
US08574271B2 |
Fixation plate screw retention
A screw fixation system includes a plate having opposed first and second surfaces, and a hole defined in the plate which extends between the first and second surface. A screw is included having a head and a shaft extending from the head and defining a longitudinal axis for the screw, the shaft of the screw being configured and adapted to be inserted into the hole. A retainer is circumferentially positioned around the shaft of the screw and proximate to the screw head. The retainer is configured to engage with the plate proximate the hole when the shaft of the screw has been inserted into the hole so as to resist removal of the screw from the hole and to allow removal of the screw from the hole when a preset torque is applied to the screw. |
US08574266B2 |
Percutaneous facet fixation system
A percutaneous facet fixation system minimally invasive, reproducible, efficient, and effective. Capable of immediate stabilization of a facet joint complex, the instrumentation and methods may be used with C-arm and/or endoscopic visualization. |
US08574261B2 |
Removable embolus blood clot filter
A removable blood clot filter includes a number of locator members and anchor members disposed radially and extending angularly downward from a hub. The locator members include a number of linear portions having distinct axes configured to place a tip portion approximately parallel to the walls of a blood vessel when implanted and to apply sufficient force to the vessel walls to position the filter near the vessel centerline. The anchor members each include a hook configured to penetrate the vessel wall to prevent longitudinal movement due to blood flow. The hooks may have a cross section sized to allow for a larger radius of curvature under strain so that the filter can be removed without damaging the vessel wall. |
US08574260B2 |
Embolic device delivery system with retractable partially coiled-fiber release
A medical device for placing an embolic device, such as an embolic coil, at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device having a headpiece coupled to the proximal end is releasably disposed within the distal end of the pusher member and retained in place by a retractable fiber, having a coiled distal portion. When the embolic device is advanced to the predetermined site within the vessel, the detachment fiber is retracted from around the headpiece of the embolic device to thereby release the embolic device. |
US08574259B2 |
Intravascular filter with drug reservoir
An intravascular filter can capture and eliminate emboli. In particular, an intravascular filter may include a plurality of filter legs extending from an apical head. The filter legs may be configured to capture emboli. A drug reservoir that includes or contains a therapeutic drug can be disposed near the apical head. The therapeutic drug, such as a thrombolytic or anti-coagulatory drug, may be eluted in response to a captured emboli. |
US08574258B2 |
Occlusion device and method of use
A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas provided over the length of the catheter. The device includes a first elongate member insertable longitudinally through the lumen of the catheter, the first elongate member being configured for stretching at least a portion of the catheter and causing one of the first and second expandable areas to transition from an expanded state to a collapsed state. The device further includes a second elongate member insertable longitudinally through the lumen of the catheter, the second elongate member being configured for stretching at least a portion of the catheter and causing the other of the first and second expandable areas to transition from an expanded state to a collapsed state. |
US08574253B2 |
Method, system and device for tissue removal
A method and device for tissue removal. The device may be used to remove uterine fibroids and other abnormal gynecological tissue. According to one embodiment, the device includes a housing, an outer tube, and an inner tube. The outer tube is fixed to the housing and includes a side window proximate to its distal end. The side window may have sloped proximal and distal ends. The inner tube has a distal end positioned within the outer tube, the distal end being adapted to rotate and, at the same time, to move back and forth past the side window, with the rotational and translational movement of the inner tube being independently controllable. The distal end of the inner tube may have an external bevel. Suction is applied to the proximal end of the inner tube to draw tissue into the side window and to remove resected tissue through the inner tube. |
US08574252B2 |
Ultrasonic blade support
An ultrasonic clamp coagulator assembly that is configured to permit selective cutting, coagulation and clamping of tissue during surgical procedures. An elongated portion of the instrument can be configured for endoscopic applications and has an outside diameter of less than 6 mm. The construction includes an outer sheath and an ultrasonic waveguide positioned within the outer sheath. The waveguide includes an ultrasonically actuated blade positioned at least partially distal the waveguide. A rigid support is positioned between the outer sheath and the waveguide. |
US08574248B2 |
Catheter system with balloon-mounted plaque-modifying elements
A plaque-modifying balloon and method for use in an endovascular procedure includes an elongated balloon that defines a longitudinal axis and is inflatable from a first deflated configuration to a second radially expanded configuration. One or more plaque-modifying elements are mounted on the outside of the inflatable balloon. Optionally, a compressible sheath made of a relatively low durometer, flexible material is mounted on the balloon to cover the elements during transit of the plaque-modifying balloon to and from the treatment site. |
US08574246B1 |
Compliant anastomosis system utilizing suture
An integrated anastomosis tool may include an effector that both makes an opening in the wall of a target vessel and connects a graft vessel to the target vessel. The effector may include a cutter assembly and a connection module that are independently actuatable. The connection between the graft vessel and the target vessel may be compliant, and may be achieved by suturing an end of the graft vessel to the side of the target vessel with the connection module. |
US08574241B2 |
Steerable stylet for an implantable medical lead, and method for manufacture thereof
A steerable stylet for a medical implantable lead has an inner lumen, into which the steerable stylet is insertable for navigating a distal end of the medical implantable lead to the desired location for attachment to tissue. The steerable stylet comprises a wire, a tube and an actuator. By means of the steerable stylet, the distal portion of the lead may be bent in desirable degree and, when the medical implantable lead is bent, the distal portion of the medical implantable lead is pivotal by means of the actuator to which the proximal end of the wire is non-rotatably connected. The tube is connected to the actuator by means of a torque limitation device which, when exceeding a predetermined torque force, will disconnect the torque connection between the tube and the actuator. A method for manufacturing of a steerable stylet for a medical implantable lead includes the step of connecting the stylet tube to the actuator by a torque limiting device as described above. |
US08574236B2 |
Method for preparing recipient site and implanting allogenic bone graft
A method of fixating allogeneic bone to an area of deficient bone in the jaws comprising: exposing the area of deficient bone by incising and retracting soft tissue; selecting a drill bit having a diameter corresponding to the area of deficient bone to receive donor bone; contacting the selected drill bit with the exposed deficient bone to form a generally cylindrical seat for receiving the donor bone; selecting a section of donor bone having a generally cylindrical shape and circular cross-section corresponding to said formed seat; fixating the donor bone to the formed seat with at least one screw; and closing the soft tissue to cover the previously exposed deficient bone. |
US08574229B2 |
Surgical tool
The invention is concerned with cauterizing and resecting tissue. A pair of electrodes are placed on opposed tissue surfaces, and radio frequency power is applied through the electrodes to cauterizing a tissue mass therebetween. After cauterization has been effected, the tissue may be resected along a plane within the cauterized region with minimum or no bleeding. The tissue mass may then be removed. |
US08574227B2 |
Tissue measurement and ablation antenna
A surgical antenna for radiating microwave energy (e.g. frequency 500 MHz to 60 GHz) from a e.g. ceramic insertion tip (60) into biological tissue is disclosed. The tip is provided at the end of an elongate body which delivers the microwave energy to the tip via an inner conductor (30), an outer conductor (20) surrounding the inner conductor and a dielectric material (50) therebetween. The impedance of the insertion tip (60) is selected to improve impedance matching with the complex conjugate of the complex impedance of the tissue at a treatment frequency. For example the insertion tip may act as or include at least one quarter wavelength impedance transformer. By closely matching the antenna's impedance to the tissue, dynamic tuning (if used) can be performed much more efficiently. Impedance matching at the tip can also focus the radiated energy distribution. |
US08574224B2 |
Surgical laser device utilizing a visible laser diode
Systems, apparatuses, and methods for a compact surgical device include a laser unit and one or more laser outlet assemblies. The laser unit has a power regulator, one or more diode laser assemblies, each having a single diode laser source, and a laser trigger mechanism. The laser unit can emit an aiming light beam and a treatment laser beam either both from the same single diode laser or from two separate single diode lasers. The beam can pass through the one or more laser outlet assemblies. The aiming light beam can have a first energy level. The treatment laser beam can have a second energy level that is substantially greater than the first energy level of the aiming light beam. |
US08574223B2 |
Method of collecting and in situ processing of aspirated fat tissue sampled from a human patient during tissue aspiration operations
A method of collecting and in situ processing of aspirated fat tissue sampled from a human patient. The method involves providing a surgeon with a powered-assisted hand-held fat tissue aspiration instrument having a cannula, and a fat tissue sampling, processing and collection device installed between the power-assisted fat aspiration instrument and a vacuum source. The fat tissue sampling, collection and processing device includes a suction plate, mounted within a collection chamber, and having multiple hollow projections for supporting the open proximal ends of a plurality of tissue collection and processing tubes, wherein each tissue collection and processing tube has micro-pores formed in the side walls thereof, and its distal end opening is capped. Aspirated fat tissue is collected in a selected tissue collection and processing tube, while allowing fluid to flow and filter through the micro-pores as aspirated fat tissue flows through the cannula of the fat aspiration instrument. |
US08574222B2 |
Anti-clog suction tip apparatus and method
An anti-clog suction tip apparatus includes a suction tip having a suction opening and an interior defining a suction channel. An ejection wire channel extends to a wire exit opening into the suction channel that is located proximate the suction opening. An ejection wire including a ball tip at an end thereof occupies the ejection wire channel and is transitionable between a retracted configuration and an advanced configuration such that, in the retracted configuration, the ejection wire including the ball tip is retained within the ejection wire channel and does not obstruct suctioning of debris through the suction channel; and in the advanced configuration, the ball tip of the ejection wire does not extend more than three millimeters beyond the suction opening. |
US08574219B2 |
Catheter shaft including a metallic tapered region
A catheter shaft including a metallic tubular member including a plurality of apertures formed in the tubular wall of the metallic tubular member to provide a desired degree of flexibility to the metallic tubular member. The metallic tubular member includes a tapered region intermediate a region and a second, reduced diameter region relative to the first region. |
US08574213B2 |
Process for preparing a lyophilized material
A process for preparing a lyophilized material, providing a container having a penetrable envelope and containing the material in a carrier liquid, whereby the penetrable region is penetrated with a penetrator which provides a conduit through the envelope, and the carrier liquid is evaporated out of the container via the conduit, after which the penetrator is withdrawn. |
US08574206B2 |
Intestinal irrigation device and method of using the device
An intestinal irrigation device that includes a waste collection bag and a rectal catheter. The rectal catheter has a first end for coupling with the waste collection bag and a free end for insertion into the rectum, while the waste collection bag has a first wall circumferentially united with an opposing second wall and an inlet opening for irrigated waste. The inlet opening has a first coupling part for coupling the rectal catheter into fluid communication with the bag, and the bag has a second coupling part inside it for mating the first coupling part. The device provides a time saving alternative to known devices, and no odor emissions and unpleasant smell is recognized during the irrigation procedure. |
US08574202B2 |
Positive displacement flush syringe
A positive displacement flush syringe includes a barrel having a chamber for retaining fluid and an elongate tip extending distally therefrom having a passageway therethrough in fluid communication with the chamber. A plunger having a stopper which is slidably positioned in said chamber for driving fluid out of the chamber by movement of the stopper relative to the barrel is provided. Further, structure is provided to move fluid distally in the passageway after fluid has been delivered from the chamber and the stopper is in contact with the distal wall of the chamber. |
US08574201B2 |
Syringe piston with check valve seal
A fluid syringe of the type used with fluid infusion devices is presented here. The fluid syringe generally includes a barrel, a piston, and a check valve seal. The barrel has an interior wall and a sealed main fluid chamber. The piston is slidably coupled within the barrel, and the piston has a piston seal forming an interference fluid seal against the interior wall. The check valve seal is coupled to the piston, and it is located between the piston seal and the main fluid chamber. The check valve seal forms an interference fluid seal against the interior wall when the piston is unloaded, and it disengages the interior wall to allow gas flow from the main fluid chamber toward the piston seal when the piston is loaded. |
US08574199B2 |
Coupling for injection devices
The present invention concerns a prefilled injection device having a container and a dose setting mechanism encapsulated inside the housing. The housing is made from two parts which are locked together by a bayonet coupling: In addition to the bayonet coupling, the two parts are also provided with irreversible locking means locking the two parts permanently together. |
US08574198B2 |
Drive mechanisms suitable for use in drug delivery devices
The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body. |
US08574190B2 |
Enteral feeding apparatus
Embodiments of the present invention include a enteral feeding apparatus and/or system in which an enteral feeding pump can be configured to deliver enteral formula to a patient in accordance with a delivery parameter determined using patient information associated with a patient to be treated and formula information associated with an enteral formula to be delivered to the patient. Exemplary embodiments can determine an estimated daily caloric intake for a patient and can configure the enteral feeding pump to satisfy the caloric requirements of the patient. Exemplary embodiments are also able to monitor the delivery of the enteral formula to ensure that the patient is being properly treated. |
US08574189B2 |
Storage and dispensing devices for administration of oral transmucosal dosage forms
Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature. |
US08574188B2 |
Drug delivery technology
The invention relates to a novel drug delivery technology. More particularly the invention relates to a method of delivering at least one therapeutic compound or a formulation comprising the at least one therapeutic compound to a patient; to a throwaway or reusable device for delivering at least one therapeutic compound or a formulation comprising the at least one therapeutic compound to a patient in a manner as set out by the method; to a pioneer projectile for use in said method; to formulations for use in said method and to an injectate comprising a pioneer projectile and formulation. It also relates to a disposable component containing either a pioneer projectile or an injectate. The invention also relates to a throwaway or reusable device for delivering at least one therapeutic compound, or a formulation comprising the at least one therapeutic compound (hereafter drug) to a patient, and a method for administering a drug to a patient using said device. It also relates to a packaged drug for use with said device. |
US08574186B2 |
Device for mucosa resection
To carry out a mucosa resection, a liquid is injected beneath a tissue which is then separated by means of mechanical or electrosurgical equipment. A device is provided that includes a facility for endoscopic water-jet surgery with a control device for regulating a pressure at which a water jet is discharged from a nozzle of the facility to obtain a predetermined amount of energy. An adjusting assembly is provided for setting the pressure to a first value and to a second value. The first value is so chosen that the water jet penetrates a mucosa in such a way that the mucosa is lifted from an underlying muscularis through formation of a fluid deposit. The second value is adjusted and different from the first value in such a way that the mucosa is sectionally cut through by the water jet. |
US08574185B2 |
Implantable arterio-venous shunt devices and methods for their use
A long-term implantable arterio-venous shunt device or creation of a fistula is provided that can be used as a therapeutic method for treating chronic obstructive pulmonary disease (COPD). The shunt device is implanted between an artery and a vein, preferably between a peripheral artery and the inferior vena cava. The shunt device and method of creating a fistula increases cardiac output and decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml/min after the implantation. Based on the effects of the method and device to the respiratory, cardiac and circulatory system, the method and device are beneficial as a therapy to patients with problems or conditions related to these systems. |
US08574183B2 |
Method and device for monitoring a blood treatment unit of an extracorporeal blood treatment device
The present invention relates to a method and a device for monitoring a blood treatment unit, subdivided by a semipermeable membrane into a blood chamber and a dialysis liquid chamber, of an extra-corporeal blood treatment device, which comprises an extra-corporeal blood circuit having an arterial branch leading to the blood chamber of the blood treatment unit, a venous branch, which extends away from the blood chamber, and a dialysis fluid system, in which the dialysis liquid chamber is arranged. The method according to the present invention and the device according to the present invention are based on the idea that the change of the flow resistance of the dialysis machine is determined based on two measurements, wherein an oscillating pressure signal in the extra-corporeal blood circuit or in the dialysis fluid system is measured before and after the change of the substitution rate and/or ultrafiltration rate, with which the substitute is applied to, or ultrafiltrate is removed from, the blood flowing in the blood circulation system. Preferably, the supply of substitute is interrupted temporarily. |
US08574180B2 |
Compression device for the foot
A compression device for the foot comprising: a wrap adapted to surround the foot, the wrap comprising at least two bladders which when inflated conform to the shape of the foot to provide compression, the bladders being positioned on the wrap so that a first bladder focuses compression on the heel of the foot and a second bladder focuses compression on the arch of the foot; a channel attached to each bladder for independently delivering fluid to each bladder; and a controller attached to the channels that generates and independently controls the flow of fluid to the bladders. |
US08574176B2 |
Rehabilitation supporting device
A rehabilitation supporting device 1 includes a first frame 11 arranged along a first skeletal portion extending from a joint, a second frame 12 arranged along a second skeletal portion extending from the joint in a direction different from a direction of the first skeletal portion, an angle sensor 131 arranged to detect a rotational angle position between the first frame and the second frame, a flexion-side biosignal sensor 14 arranged to detect a biosignal of a flexor, an extension-side biosignal sensor 15 arranged to detect a biosignal of an extensor, a calibration unit 31 arranged to determine a flexion-side correction value and an extension-side correction value individually, and a memory unit 34 arranged to store individual correction values of the biosignals different for individuals, the flexion-side correction value, and the extension-side correction value. |
US08574174B2 |
Combination ultrasound-phototherapy transducer
A soundhead of a treatment device is provided that enables a volume of tissue located beneath the soundhead to simultaneously receive ultrasound and light stimulation. According to one embodiment, the soundhead includes an ultrasound transducer, a light source, and a faceplate extending across a face of the transducer for providing a tissue contacting and ultrasound energy coupling surface of the soundhead. The faceplate is transparent or translucent to the light generated by the light source. Alternate embodiments including externally mounted light sources are also disclosed. |
US08574170B2 |
Guidewire
A guidewire comprising an elongate guide member dimensioned for insertion within a body vessel of a subject is disclosed. The guide member defines a longitudinal axis and has trailing and leading end segments. The leading end segment has a reduced cross-sectional dimension relative to a cross-sectional dimension of the trailing end segment. The leading end segment includes at least one finger thereon. A first transverse dimension of the finger is greater than a corresponding first transverse dimension of the leading end segment in contact therewith. |
US08574165B2 |
Hydration monitor
A hydration monitor includes a temperature sensor (20; 65) for measuring a subject's core body temperature and a processor (30). The processor is arranged to accept measurements from the temperature sensor (20; 65) and calculate a hydration level in dependence on changes in the measured core body temperature. |
US08574164B2 |
Apparatus and method for detecting a sleep disordered breathing precursor
A device according to some embodiments may include a primary antenna configured to be located external to a subject. The device may also include at least one processor in electrical communication with the primary antenna and configured to receive a condition signal from an implantable device, the condition signal indicative of a precursor to sleep disordered breathing, and cause transmission of a primary signal from the primary antenna to the implantable device, in response to the condition signal, to stimulate at least one nerve in response to the precursor to sleep disordered breathing. |
US08574162B2 |
Systems and methods for detecting pulses
According to embodiments, systems and methods are provided for detecting pulses in a PPG signal. Local minima and maxima points may be identified in the PPG signal. Each minimum may be paired with an adjacent maximum forming an upstroke segment. Noise may be removed by comparing adjacent segments and ignoring segments that are too long or too large. Notches in the pulse may be identified and ignored by analyzing adjacent segments. Adjacent upstroke segments may be combined as a single upstroke if the lengths of adjacent upstroke segments are about the same, have similar slopes, and the end point of one segment is close to the start point of an adjacent segment. Segments having small temporal or amplitude difference relative to adjacent segments may be disregarded. The remaining segments may represent the pulse upticks. A sliding time window may be used instead to detect pulses in the PPG signal. |
US08574158B2 |
Time of flight estimation method using beamforming for acoustic tomography
It is disclosed an acoustic tomography method to improve the time of flight estimation, said method comprising the steps of: sequentially triggering a set of N transmitters so as to generate a sequence of N acoustic waves through a volume being scanned; receiving each of said acoustic waves after transmission through said volume with a set of M receivers, which are called received signals; delaying by varying delays the N different said received signals that each receiver receives from the N different transmitters, and adding them together to form a new received signal, which is called transmit-beamformed signal for that receiver; delaying by varying delays the M different said transmit-beamformed signals for each receiver and adding them together at each receiver to form a new signal, which we call transmit-receive-beamformed signal. |
US08574151B2 |
In-vivo information acquiring system and body-insertable apparatus
A body-insertable apparatus includes an imaging unit that captures an in-vivo image of a subject; a signal processing unit that writes the in-vivo image in a memory, reads the in-vivo image from the memory on a pixel basis and converts the in-vivo image to serial information to transfer the serial information; and a rate converter that converts a transfer processing rate to a rate higher than a writing processing rate. The transfer processing rate is at which the signal processing unit reads the in-vivo image from the memory and converts the in-vivo image to the serial information to transfer the serial information. The writing processing rate is at which the signal processing unit writes the in-vivo image in the memory. The apparatus also includes a transmitting unit that wirelessly transmits the serial information transferred from the signal processing unit at a transmission rate corresponding to the transfer processing rate. |
US08574150B2 |
Capsule medical apparatus
A capsule medical apparatus to be introduced into a subject includes a tissue collecting unit that collects in-vivo tissue; a storage unit that stores therein the in-vivo tissue that is collected by the tissue collecting unit; a liquid storing unit that stores therein liquid for suppressing autolysis of in-vivo tissue; a liquid supplying unit that supplies the liquid in the liquid storing unit to the storage unit; and a control unit that allows, in response to an instruction to start collecting the in-vivo tissue, the tissue collecting unit to collect desired in-vivo tissue and to store the collected in-vivo tissue in the storage unit and that then allows the liquid supplying unit to supply the liquid to the storage unit and makes the storage unit be in a liquid-tight state. |
US08574147B2 |
Pressure-to-tension conversion device for treating urinary incontinence
Disclosed is a pressure-to-tension conversion device for treating urinary incontinence. The pressure-to-tension conversion device includes resilient sections which are inserted in and occupy Retzius spaces positioned in left and right sides of the urethra in front of the urinary bladder, respectively, and a support extending below the urethra and across the resilient sections in a “V” shape, wherein if the resilient sections are deformed as the abdominal pressure increases and the Retzius spaces contract, the support is tensioned, thereby supporting the urethra, so that the urinary incontinence can be treated. Consequently, the length of operation time for transplanting the pressure-to-tension conversion device can be shortened, a complication or a side effect can be reduced, and the charges of operation can be reduced. In addition, expensive operation materials can be substituted by the pressure-to-tension conversion apparatus, the costs for operation materials can be saved. |
US08574144B2 |
Method for extracting particulates from a continuous flow of fluid
A centrifuge is employed to continuously remove particulates from a fluid. In one embodiment, the centrifuge removes small particles of soot from lubricating oil of large diesel engines. The fluid in introduced into the centrifuge through an inducer so that vortexes are not propagated in the fluid. Flow constrainers and flow straighteners maintain laminar flow of the fluid as it passes axially through the centrifuge. An exducer decelerates the fluid prior to its exit from the centrifuge. The exducer thus contributes to maintaining laminar flow conditions. Laminar flow may contribute to the soot-removal effectiveness of the centrifuge. |
US08574143B2 |
Compliant design of a horizontal solid-bowl centrifuge with cleaning-in-place nozzles
A horizontal solid-bowl centrifuge with cleaning-in-place jet nozzles for cleaning the bowl in a manner complying with good manufacturing procedure is provided. The bowl is cleaned by a defined arrangement of the cleaning jet nozzles, as the bowl rotates at a speed insufficient to produce a centrifugal force equal to gravitational acceleration, where gravitational acceleration is equal to 1.0 g. The cleaning liquids are then removed after the bowl stops rotating at the lowest point of the bowl. |
US08574138B2 |
Slidable exercise apparatus
A slidable exercise apparatus includes a pair of platforms, each platform including a base having opposed upper and lower generally planar surfaces and a generally rigid construction. A pad has a lower surface attached to the base upper surface and has a generally cushioned construction. Each platform includes a plurality of skid plates situated on the base lower surface, each skid plate having a smooth outer surface configured to slide on a floor surface. |
US08574137B2 |
Upper limb training device
An upper limb training device includes a first rod, a second rod, a third rod, a first resilient element, and a second resilient element. The second rod is pivoted to the first rod by a first revolution element. The third rod is pivoted to the second rod by a second revolution element. Two ends of the first resilient element respectively connect with the first rod and the third rod for providing resistance when the first rod and the second rod rotate relative to the third rod. Two ends of the second resilient element respectively connect with the first rod and the third rod for providing resistance when the first rod rotates relative to the second rod. The first revolution element is disposed between two connecting points at which the first resilient element and the second resilient element connect with the first rod. |
US08574133B2 |
Collapsible athletic training ladder
A collapsible ladder for use primarily for athletic training and the like has a plurality of spaced-apart, substantially rigid rungs secured with collapsible connectors to a plurality of spaced-apart, substantially rigid spacers extending therebetween. In one disclosed embodiment, the collapsible connectors are strips of flexible material extending between the rungs and spacers. Another disclosed embodiment has a second set of rungs aligned substantially parallel to the plurality of spaced-apart rungs along a common central set of spacers. The collapsible connectors allow the ladder to be quickly and easily transitioned between an extended, operational position, and a collapsed, storage position. |
US08574129B2 |
Exercising apparatus
An exercise apparatus includes a frame and a load mechanism disposed on the frame. The load mechanism has a plurality of selectable weights with each of the selectable weights having an associated indicator device. A press is mechanically coupled to the load mechanism to displace a load based on a selected weight and a sensor is disposed to measure an extent and speed of displacement of the load. A processor is in communication with the sensor, and the processor is configured to determine an indicator signal to send to the indicator device of one of the plurality of selectable weights of the load mechanism based on received performance data, the indicator signal used to indicate which one of the plural of weights to select. |
US08574127B2 |
Vehicle engine control device
A vehicle engine control device stopping fuel injection if a predetermined fuel cut condition is satisfied, is provided, during running with the fuel injection stopped, when inertia of a power transmission system rotating with the engine has a smaller rate of inertia of the power transmission system acting on rotation of an output shaft of the engine, the fuel injection being started at a lower engine rotation speed as compared to the case of a larger rate of inertia of the power transmission system acting on rotation of the output shaft of the engine, a clutch capable of connecting and interrupting power transmission between the engine and the power transmission system being interposed between the engine and the power transmission system, a rate of inertia of the power transmission system acting on rotation of the output shaft of the engine being configured to decrease as a clutch stroke of the clutch that is an operation amount of a clutch pedal increases, and an engine rotation speed for starting the fuel injection being set to a lower value as the clutch stroke increases. |
US08574126B2 |
Vehicle and fuel feed stop controller
A vehicle including an engine coupled to a transmission via a clutch, includes a fuel feed stop controller configured to stop fuel feeding to the engine when a first fuel feed stop condition is satisfied, and a clutch state detector configured to detect whether the clutch is engaged or disengaged, wherein the fuel feed stop controller is configured to resume the fuel feeding to the engine, when a second fuel feed stop condition continues to be satisfied and the clutch continues to be disengaged for a predetermined delay time from a time point when the first fuel feed stop condition is satisfied and the clutch state detector starts to detect that the clutch is disengaged. |
US08574125B2 |
Methods and systems for assisted direct start control
Methods and systems are provided for reducing audible clunks and objectionable drive feel in vehicles including start/stop systems. In one example, a vehicle engine is shutdown during vehicle coasting. The vehicle engine is then restarted, while the vehicle is moving with a torque converter clutch disengaged. A transmission clutch pressure is then adjusted during the restart based on a torque converter output speed relative to a torque converter input speed. |
US08574120B2 |
Vehicle driving system control apparatus
A vehicle driving system control apparatus includes a power transmission device and a power transmission control section. The power transmission device includes an engine input shaft, a motor input shaft, an output shaft, an engine-side gear mechanism transmitting a power of the engine input shaft to the output shaft, a motor-side gear mechanism transmitting a power of the motor input shaft to the output shaft, a first clutch enables and disables a power transmission between the engine input shaft and the motor input shaft, a second clutch enables and disables a power transmission between the motor-side gear mechanism and the output shaft, and a third clutch enables and disables a power transmission between the engine-side gear mechanism and the output shaft. The power transmission control section determines statuses of the clutches and required torques of motor generators in correspondence with a rotation speed of an axle. |
US08574119B1 |
Pinion carrier assembly
A pinion carrier includes a shell including a face plate, a lip spaced axially from the face plate, a hub including a plate spaced from face plate and a collar spaced axially from the lip, posts, each post spaced angularly about an axis, secured to the plate and face plate by welds, shafts spaced angularly about the axis, secured to the plate and face plate, and pinions, each pinion supported on one of the shafts. |
US08574116B2 |
Compressor with transmission
A compressor includes a housing, a compression mechanism, an input shaft rotatable on an axis thereof, an output shaft for driving the compression mechanism, a transmission for transmitting torque from the input shaft to the output shaft and also changing the rotating speed of the input shaft and a control device for controlling the operation of the transmission. The transmission includes a plurality of planetary rollers, a carrier rotatably supporting the respective planetary rollers and being integrally rotatable with the input shaft, a sun roller engaged with the respective planetary rollers and integrally rotatable with the output shaft and a ring roller engaged with the respective planetary rollers. The ring roller can be fixed to the housing or rotatable relative to the housing. The control device includes a one-way clutch allowing the ring roller to rotate only one direction relative to the carrier and a clutch fixing the ring roller to the housing or allowing the ring roller to rotate relative to the housing. The input shaft, the carrier, the respective planetary rollers and the sun roller cooperate to form an assembly that can move as a unit relative to the housing in the direction that is parallel to the axis. |
US08574113B1 |
Multiple speed transmission
A family of transmissions produces at least eight forward and one reverse speed ratio by selective engagement of various combinations of three clutches or brakes. Each transmission includes two fixed gearing arrangements that establish fixed speed relationships between an input shaft, and output shaft, and four other elements. Specifically, the input shaft is constrained to rotate at a speed between that of the first and second elements while the output shaft is constrained to rotate at a speed between that of the third and fourth elements. Additional gearing, clutches, and brakes establish specified selective speed relationships among these elements. |
US08574105B2 |
Front derailleur with variable attachment to a bicycle frame
A front derailleur that includes a variable attachment to a mounting socket of a bicycle frame. The front derailleur includes a base member, a chain cage, a parallelogram and an attachment member. The base member includes first and second pivot points and at least two attachment points. The parallelogram includes two parallelogram arms, each having first and second ends. The first ends are pivotable about the first and second pivot points of the base member and the second ends support the chain cage. The attachment member connects the base member to the mounting socket of the bicycle frame through one of the at least two attachment positions. The base member also includes a contact surface for mating with the mounting socket. The different attachment positions allow the position of the front derailleur to be adapted to a standard or compact set of chainrings. |
US08574100B2 |
Method for fitting golf club
A fitting method includes steps of preparing a relationship C of a shaft flex point Y and a face angle X before impact or at impact; measuring a subject's face angle X before impact or at impact by using a test club; and selecting a shaft fitted to the subject on the basis of the measured face angle X and the relationship C. The relationship C is created by using correlation R of the face angle before impact or at impact and a hitting result. The correlation R is based on hitting results of a plurality of golf clubs having different shaft flex point rates. Preferably, the relationship C is a relational expression F1. |
US08574099B2 |
Par one
A golf system that includes a tee or other area for striking a golf ball; and a golf green having a concave surface with a ball receptacle located at the lowest point in the surface so that a ball landing and remaining on the green will roll into the ball receptacle. The green includes a resiliently compressible layer coinciding with the concave surface. The resiliently compressible surface may include at least one layer of corrugated plastic material and may be covered with an artificial turf surface. The golf system may be used to play a unique game, wherein a plurality of balls are rolled on the green and travel in a spiral manner into the ball receptacle. The golf green may be mounted on a portable frame. |
US08574091B2 |
Method and apparatus for determining golf ball performance versus golf club configuration in accordance with a golfer's individual swing characteristics
An apparatus and method is provided for analyzing a golfer's individual swing attributes and determining, based on that analysis, a suitable golf club configuration for that golfer. The swing analysis apparatus include video cameras for obtaining video images of a golfer swinging a golf club, such as a putter, at a golf ball. Images obtained from the video cameras may then be analyzed to determine what golf club dimensions will provide improved results in combination with the golfer's individual swing characteristics. The apparatus may additionally include a golf club having predetermined dimensions. When such a golf club is included, images from the video cameras may be analyzed to determine how the golf club of known dimensions must be adjusted to provide the golfer with desirable swing results. The apparatus may also include a method for confirming the dimensions that it is believed will provide a golfer with improve swing results. |
US08574090B1 |
Foot anchor for golf
A rotating foot anchor comprises a base, a pivot pin, and a spring strap. The foot of a user is placed on the base and beneath the spring strap. The foot anchor provides smooth rotation of the user's foot during a follow-through of a golf swing. The pivot pin comprises a downward pointed protrusion which penetrates a ground surface to further secure the device. As the user swings a golf club, the pivot pin enables the foot anchor along with the user's foot to rotate and therefore relive stress applied to the player's knees and back. |
US08574087B1 |
Mechanical ride safety system
A mechanical ride safety system for automatically disabling a mechanical ride in response to a rider losing his/her grip on the ride. The mechanical ride safety system generally includes a gripping member that is grasped by a rider when the ride in in use. The gripping member includes a sensing member which is adapted to sense whether the gripping member is being grasped or has been released. A processing unit and transmitter are communicatively interconnected with the sensing member so that a signal may be transmitted when the gripping member is released. A receiver is communicatively interconnected with the control unit of the mechanical ride such that, upon receiving a signal indicating that the gripping member has been released, the control unit will automatically disable the mechanical ride to prevent injury to the rider. |
US08574086B2 |
Electric fires
The disclosure relates to simulated flame effect fires which include an apertured bed, such as a simulated fuel bed, a vapour generating means such as an ultrasonic transducer and means for providing a rising current of air to carry the vapor through the apertured bed. Light sources are provided below the fuel bed to provide localized illumination. |
US08574080B2 |
Game controller, storage medium storing game program, and game apparatus
A game controller includes at least four load sensors for detecting a load applied on a support board on which player's legs are ridden, and the game controller transmits a load value detected as manipulation data by the four load sensors to a game machine. The game machine determines a necessary quantity of load values, and the game machine computes the necessary quantity of load values based on the detected load value from the game controller. Then, game processing is performed based on the necessary quantity of computed load values. |
US08574078B2 |
Game apparatus, communication apparatus, wireless game controller, and game system
A technology of realizing wireless communication between a parent station and child stations with efficiency. In a game system according to the present invention, a game apparatus sets the maximum number of times of transmission for wireless game controllers, in accordance with the number of wireless game controllers that are communicating at a predetermined communication cycle. Here, time for establishing connection with a new wireless game controller is reserved within each communication cycle, thereby allowing new users to join the game. The maximum number of times of transmission is re-set when the number of wireless game controllers connected changes. |
US08574076B2 |
Updating virtual worlds based on interactions between real-world items
A method of updating virtual worlds based on interactions between real-world items is disclosed. An interaction between a first real-world item and a second real-world item is detected. The first real-world item is a real-world item that is associated with a first player of a computer-implemented game and the second real-world item is a real-world item that is associated with a second player of the computer-implemented game. A virtual world of the computer-implemented game is updated based on the detection of the interaction. |
US08574073B2 |
Game system, game device, storage medium storing game program, and game process method
An example game system includes a game device, a controller, and a terminal device which is a portable display device. The terminal device displays an image representing a ball placed in a virtual game space. The game device calculates the attitude of the controller to move a club in the game space based on the attitude, and moves the ball in response to the club striking the ball. An image of the game space including at least the ball after being moved is displayed on a display device separate from the portable display device. |
US08574072B2 |
Visually presenting wagering game options
In some embodiments, a wagering game server includes an options visualization controller configured to receive search criteria and filter information for searching wagering titles, wherein the search is based on the search criteria and filter information. The server may include a game content unit configured to store the wagering game titles. The wagering game system can also include a wagering game machine configured to present the one or more wagering games in a visual map, the visual map comprising nodes that contain summary information associated with the wagering game titles, wherein the nodes are arranged in node groups, and wherein the node groups are graphically connected by graphical connectors. The wagering game machine can present a movable filter object configured to visually depict a filter criteria, wherein the movable filter object is movable onto one or more of the nodes to provide the filtering information to the wagering game server. |
US08574071B2 |
Information storage medium and image generation system
An image generation system that generates an image includes: a movement control section that moves a player's moving object in a virtual three-dimensional space based on input information; and an image generation section that generates an image of the virtual three-dimensional space viewed from a given viewpoint. The movement control section performs a follow-up control process that causes the player's moving object to follow a target moving object based on previous movement information about the target moving object. |
US08574070B2 |
Gaming system incorporating a multi-directional display
A gaming system includes a multi-directional display and a one-way mirror. The multi-directional display is configured to display a first visual image that is directly viewable along a central viewing axis, and to further display a second visual image that is directly viewable along a first angular viewing axis. The one-way mirror is positioned with reference to the multi-directional display for reflecting the second visual image along a second angular viewing axis while permitting direct viewing of at least a portion of the second visual image through the first one-way mirror along the first angular viewing axis. |
US08574069B2 |
Hand-held game apparatus and game program
A hand-held game apparatus and a game program are provided which allow a user to play a game while going back and forth between two kinds of maps, namely, a narrow-range map and a broad-range map game, and arbitrarily change the displayed state of at least one of the broad-range map and the narrow-range map by manipulating a touch panel which is mounted on a liquid crystal display section for displaying the broad-range map. If the player manipulates the touch panel to point to a coordinate position on the broad-range map, thus designating coordinates for a narrow-range map to display, an image of the narrow-range map, which is changed as desired, is displayed. If the player indicates a moving direction on the broad-range map, thus designating a scroll direction, the broad-range map is moved (scrolled). |
US08574062B2 |
System and method for saving status of paused game of chance
A game of chance involving a progression of events is conducted on one or more gaming machines. After receiving a wager from a player at a gaming machine, play of the game is initiated. If the game is paused, the status of the paused game is stored at a central database linked to and remote from the gaming machine. This game status is associated with a personal identifier of the player. To continue play of the game beginning from a point at which the game was paused, the personal identifier is provided to the central database via the same or another gaming machine and the game status associated with the personal identifier is retrieved from the central database. |
US08574061B2 |
Gaming device including player selectable wild symbols
A gaming system configured to operate a game associated with a plurality of symbols. For a play of the game, the gaming system displays a plurality of reels, each of the reels including a plurality of the symbols and being associated with a plurality of symbol display areas. For an activation of the reels, the gaming system randomly generates and causes each of the reels to display one of the symbols on that reel at each of the symbol display areas associated with that reel. Upon an occurrence of a triggering event, the gaming system: adds one or more wild symbols to one or more of the reels and provides a plurality of additional activations of the reels. If a removal condition is satisfied prior to a final one of the additional activations of the reels, the gaming system removes a remaining wild symbol from one of the reels. |
US08574060B2 |
Gaming machine arranging two symbol columns in the same order
The present invention may be gaming machine, including a mechanical reel which is configured with a plurality of rotatable reels, each reel indicating indicia on a circumferential surface of the reel, a display which shows a part of the circumferential surface and a controller which stops two reels to indicate the same kinds of indicia with the same arrangement on the circumferential surface of each of the two reels shown on the display, the two reels being installed contrastively to a vertical axis dividing a plurality of the rotatable reels. |
US08574055B2 |
Method of lottery wagering on real-world events
Methods for direct wagering and lottery wagering on real-world events including outcomes based on fantasy sports league performance. One method according to an embodiment of the present invention includes selecting a set of variables, each variable representing a time-varying value capable of having a fixed value at a specified time. For each variable, the method includes selecting a range of values for the fixed value of the variable at the specified time, dividing the range of values into a set of n increments, randomly assigning a lottery number from a set of lottery numbers, 1 to n, to each increment, selecting a winning lottery number from the set of lottery numbers based on correlating the fixed value of the variable at the specified time with the increment associated with the winning lottery number; and determining a set of winning lottery numbers from the winning lottery numbers selected for each variable. |
US08574054B2 |
3D reels
A mechanical reel (32) for a gaming system (10) is disclosed. The reel (32) has a circumferential reel surface (48). The reel (32) has at least one symbol bearing surface (50) offset from the reel surface. |
US08574042B1 |
Game cleaning system
An apparatus for removing a portion of a hide from an animal is provided. The apparatus includes a base, and a tether that is adjustable relative to the base. A hide connector is included, and cooperates with a portion of loose hide that extends from the animal, but is connected to a remaining portion of the hide on the animal that is to be removed. An animal connector cooperates with a portion of the animal. One of the hide connector and the animal connector is coupled to the base and the other one of the hide connector and the animal connector is coupled to the tether. A driver is provided to adjust a position of the tether relative to the base and cause separation of the hide connector and the animal connector, thereby removing at least some of the remaining portion of the hide from the animal. |
US08574040B2 |
Multi-air aqua reservoir moist sanding system
An abrasive disc includes a backing layer on a first major surface, a water-impermeable abrasive layer on a second major surface, and a water-absorbable, compressible, resilient, porous foam layer sandwiched in between the backing layer and the abrasive layer. The disc further includes a plurality of perforations. The disc is used to abrade a surface. Fluid is absorbed into the abrasive disc. The fluid is then released to the surface by compressing the abrasive disc against the surface in an abrading motion. The fluid is allowed to mix with and absorb surface swarf; and compression on the abrasive disc is released, reabsorbing the fluid and trapping swarf inside the disc. |
US08574033B2 |
Wafer support member, method for manufacturing the same and wafer polishing unit comprising the same
Disclosed is a wafer support member including a base substrate, a support adhered at a predetermined width to the edge of the base substrate, the support having a round outermost part, and a coating layer provided on the outermost edge of the support. |
US08574031B2 |
Method of and apparatus for grinding cylindrical and curved surfaces
A workpiece has two cylindrical workpiece surfaces centered on respective parallel axes and each flanked by a pair of arcuately rounded and annular corners also centered on the respective axes. Some of the corners have a small radius of curvature and others of the corners have a large radius of curvature. The workpiece is held and rotated about a main axis parallel to the axis of one of the workpiece surfaces. A pair of grinders have wheels generally diametrally flanking the workpiece and each having a central cylindrical outer wheel surface centered on the respective wheel axis and a pair of arcuately rounded edge and surfaces also centered on the respective wheel axis. Two of the edge surfaces are the large radius and the other two of the small radius. |
US08574030B2 |
Method of making an ice skate blade
A sharpening machine generally includes a grinding wheel having a perimeter that is rotatable about a first axis. The sharpening machine includes an adjustment device adapted to be coupled to a structure of the sharpening machine. A shaft, mounted to the adjustment device, defines a second axis that is generally parallel to the first axis when the adjustment device is coupled to the structure and is movable along a predetermined feed axis toward the grinding wheel. A carousel is rotatably connected to the shaft of the adjustment device. A contouring tool having a counter surface is rotatably connected to the carousel. Movement of the shaft of the adjustment device along the feed axis is configured to translate the carousel and move the contouring tool into and out of engagement with the grinding wheel to facilitate dressing of the perimeter of the grinding wheel to a grinding wheel contour. |
US08574027B2 |
Clothing article with an integrated body support
A clothing article with an integrated body support for molding and shaping the wearer's torso, includes a tubular outer garment having a free bottom end, wherein the tubular outer garment comprises an upper section adapted for supporting the bust of the wearer, and a lower section extending from the upper section for covering at least the lower torso of the wearer. The clothing article further includes a tubular inner body support extending substantially concealed in a concentric relationship with and peripherally attached to the interior portion of the outer garment, wherein the inner body support is composed of a resilient form-fitting fabric for imparting compressive support to mold and shape the lower torso and abdominal areas of the wearer. |
US08574025B2 |
Body slimmer
A stretchable undergarment comprises a one-piece body slimming unit made of front and rear panels cut and sewn along the edges to form a tubular body shaping garment construction which is stretchable in the longitudinal direction, and having a lightweight zippered opening along the front. The undergarment is made from a woven stretchable satin material containing a small amount of thin spandex-type elastic fibers forming a predominately one-way vertical stretch in a base textile fabric made from thin polymeric textile fibers such as nylon. |
US08574022B2 |
Toy vehicle
In one embodiment there is provided a toy car that includes four wheels which have a weight that is at least 40%, 50%, 70% or 80% of the total weight of the car. In another aspect each wheel has a center point, with a combined weight such that a horizontally planar center of gravity defined by the car and measured from a lowest point on an outer edge of the four wheels towards a center of the body is positioned substantially about the center point of the four wheels. In either embodiment, the body may include an upper outer portion and the upper outer portion includes a finger detent. |
US08574021B2 |
Foldable toy vehicles
A toy vehicle reconfigurable between unfolded and folded configurations includes a generally body pivotally supporting a pair of generally planar driving systems on either lateral side. Each driving system includes a motor and gear train driving a continuous track passed over multiple pulley wheels. One pulley wheel of each driving system is carried on an arm mounted to a frame of the system so as to pivot between retracted and extended positions and spring loaded to the extended position. The tracks are sufficiently elastic to accommodate the movement of the one wheel from the extended position to a retracted position. The arms are pushed into the retracted position when the vehicle is pushed into a combined remote control unit and storage case. |
US08574019B2 |
Outboard motor control apparatus
In an apparatus for controlling operation of an outboard motor having an internal combustion engine to power a propeller, and a transmission selectively changeable in gear position to establish speeds including at least a first speed and a second speed and transmitting power of the engine to the propeller with a gear ratio determined by established speed, it is configured to determine whether the transmission is in a reverse position, and control operation of the transmission to change the gear position from the second speed to the first speed when the second speed is selected and the transmission is determined to be in the reverse position. With this, it becomes possible to prevent the thrust of the boat from decreasing. |
US08574016B1 |
Key type wiring connection switch
A key type wiring connection switch includes an insulation main body, a plurality of spring elements, retaining terminals, conducting terminals and pressure buttons. In which a plurality of retaining spaces are formed in the interior of the insulation main body, The pressure buttons are positioned above each of the retaining terminals. Moreover, an upper end of each of the pressure buttons protrudes out the insulation main body. When using the present invention, the user presses downward on each of the pressure buttons to cause each of the lower ends of the pressure buttons to move downward and push open the retaining terminals, thereby enabling connecting wires of a host machine to be extended into the conducting terminals through side through holes of the insulation main body. Accordingly, when wiring an electrical appliance, there is no need for hand tools while still enabling wiring to be carried out. |
US08574015B2 |
Electrical connector
An electrical connector includes an elongated insulating housing defining a number of passageways and power terminals received in corresponding passageways. The passageways are arranged side by side along a longitudinal direction of the insulating housing. Each power terminal has a first terminal and a second terminal oppositely arranged beside the first terminal. The first terminal has a first contacting portion, a first fixing portion extending towards the second terminal, and a first connecting portion connecting the first contacting portion and the first fixing portion. The second terminal has a second contacting portion oppositely arranged beside the first contacting portion of the first terminal. A curved intermediate region is formed between the first connecting portion and the first contacting portion of the first terminal. A width of the first fixing portion is larger than a distance between the first contacting portion and the second contacting portion. |
US08574014B2 |
Assembly and system of datacommunication cables and connectors
A datacommunication interconnection system includes (a) an extension trunk cable-connector assembly and (b) a trunk cable-connector assembly. The extension trunk cable-connector assembly comprises: a first cable including a plurality of first subunits, each of the first subunits comprising a plurality of twisted pairs of conductors; a jack attached to one end of the cable; and a plug attached to an opposite end of the cable. Each of the jack and the plug includes a contact for each of the conductors of the cable. The trunk cable-connector assembly comprises: a second cable including a plurality of second subunits, each of the second subunits comprising a plurality of twisted pairs of conductors; a plug attached to one end of the second cable and connected with the jack of the extension trunk cable; and a plurality of RJ-45 connectors attached to subunits at an opposite end of the second cable. |
US08574011B2 |
Electronic connector
An electronic connector comprises an insulated housing, a first terminal pin set, a second terminal pin set, a third terminal pin set, a detective terminal pin and a metal shell. The insulated housing contains a base plate and defines a first space and a second space. The first, second and third terminal pin sets are located in the first and second spaces and work together to conform to the standards of USB 2.0 and 3.0. The detective terminal pin is disposed on an inner surface defining the first space. The metal shell encases the insulated housing and is electrically grounded. Thereby, when an interface is reversely inserted into the first space, the detective terminal pin can be electrically grounded. Such manner will allow the terminal pin sets to be selectively activated or deactivated according to the way of insertion of the interface into the connector to achieve a reliable communication. |
US08574009B2 |
Compact electrical connector
An electrical connection device comprises a receptacle connector disposed on a side of a circuit board and a plurality of terminals. The receptacle connector comprises a housing, the housing having a body; an accommodating groove locating in the front of the body and opening upwards; a plurality of terminal grooves provided in the body, intervally arranged and in communication with the accommodating groove. The terminals are correspondingly disposed into the terminal grooves, respectively and each of the terminals can include a fixing portion uprightly secured in the first terminal groove; an U-shaped resilient arm folded forwards and then extending upwards from a lower end of the fixing portion; a contact portion formed at a distal end of the U-shaped resilient arm and extending into the accommodating groove; and a soldering portion extending upwards from an upper end of the fixing portion. |
US08574007B2 |
Electrical connector having a shielding adapter to radially compress a shielding ferrule onto a cable
An electrical connector assembly is provided having an electromagnetic interference shield. The electrical connector assembly includes a backshell having a backshell bore and a shielding ferrule positioned within the backshell bore to provide an electromagnetic interference shield. The shielding ferrule includes an outer ferrule portion arranged circumferentially around an internal ferrule bore, and a shielding adapter received within the backshell bore of the backshell. The shielding adapter includes a cable extending longitudinally through the shielding adapter and the internal ferrule bore, the shielding adapter engaging the shielding ferrule such that axial movement of the shielding adapter towards the shielding ferrule radially compresses the shielding ferrule onto the cable. The shielding ferrule provides a substantially 360° electromagnetic interference shield around the cable. |
US08574000B1 |
Network cable assembly and protective sleeve thereof
A protective sleeve disposed around a cable and a connector which are connected includes a cable sleeve and a plurality of resilient elements. The cable sleeve includes a bushing, a first ring, and a second ring. The front of the bushing is connected to the connector. The first ring and the second ring are disposed around the cable. The resilient elements are formed by extending the second ring and spaced apart from each other to form an opening for penetration by the cable. The caliber of the opening is less than the caliber of the second ring. Accordingly, the resilient elements are conducive to the positioning of the cable while the cable is penetrating the rings. |
US08573998B2 |
Charging connector
A charging connector (10) is provided to be connected to a vehicle-side connector (50) for charging a battery in a vehicle. The charging connector (10) has a main body (11) including a connector fitting (13) connectable to the vehicle-side connector, a lock (22) for holding the vehicle-side connector (50) and the connector fitting portion (13) in a connected state by being locked to a lock projection (52) on the vehicle-side connector (50), an unlocking portion (23) for canceling the locked state of the lock (22) and the lock projection (52), and an unlocking hole 16 formed in the connector main body (11) at a position corresponding to the unlocking portion (23). The unlocking portion (23) projects to the outside of the main body (11) through the unlocking hole (16) and includes recesses (27) at positions facing the peripheral edge of the unlocking hole (16). |
US08573996B2 |
Coaxial cable connector having electrical continuity member
A coaxial connector comprising a connector body; a nut, axially rotatable with respect to the connector body, the nut having a first forward end configured for threadably attaching to an interface port and a second rearward end; and a continuity member, electrically contacting the nut; wherein the connector is configured to maintain return loss below −40 dBvM when the connector is installed on the interface port, so as to be only engaged with one thread of the interface port is provided. |
US08573995B2 |
Dual orientation connector with external contacts and conductive frame
A dual orientation connector having a connector tab with first and second major opposing sides and a plurality of electrical contacts carried by the connector tab. The plurality of contacts includes a first set of external contacts formed at the first major side and a second set of external contacts formed at the second major side. Each individual contact in the first plurality of contacts is electrically connected within the tab or body to a corresponding contact in the second plurality of contacts. In some embodiments contacts in the first and second pluralities of contacts that are directly opposite each other are coupled together. In some other embodiments, contacts in the first and second pluralities of contacts that are in a cater cornered relationship with each other are coupled together. The first plurality of contacts are symmetrically spaced with the second plurality of contacts and the connector tab is shaped to have 180 degree symmetry so that it can be inserted and operatively coupled to a corresponding receptacle connector in either of two insertion orientations. |
US08573994B2 |
Connector handle for an electric vehicle battery charger
A connector handle for an electric vehicle battery charger is provided. The connector handle includes a latch that is operable to a locked position and an unlocked position. The connector handle also includes an electric circuit configured to provide an enable indication and a disable indication. The connector handle also includes an actuator button moveable to a first position where the latch is in the locked position and the electric circuit provides the enable indication, a second position where the latch is in the locked position and the electric circuit provides the disable indication, and a third position where the latch is in the unlocked position and the electric circuit provides the disable indication. |
US08573993B2 |
Connector
A connector includes a first connector and a second connector configured to engage with the first connector to establish electrical connection, wherein the first connector includes a first contact terminal, and the second connector includes: a second contact terminal configured to come in contact with the first contact terminal; a switch part connected to the second contact terminal and including a fixed part and a movable part; and a movable member capable of pushing the movable part toward the fixed part, wherein the movable member is pushed by the first connector when the first connector engages with the second connector, and the movable member pushes the movable part toward the fixed part to bring the movable part in contact with the fixed part. |
US08573989B2 |
Memory card reader
A memory card reader is provided, which includes a printed circuit on which a memory card connector is mounted. The memory card connector has a slot intended for inserting a memory card and a set of contact points enabling data exchange between the memory card and a processor mounted on the printed circuit. The printed circuit is further equipped with an anti-intrusion device formed and positioned such that the anti-intrusion device prevents access, from the exterior of the reader, to at least one connection portion between at least one of the contact points of the set of contact points and the printed circuit. |
US08573985B2 |
Contactors for electric vehicle charging system
The general field of invention is electrical connectors and their conductor geometry. This patent teaches how to make the register-free charge couplers to have self-cleaning ability as well as tolerating operation under dirty environments such as underbelly of cars, while still delivering the requirements imposed by the register-free functionality. Although this invention can benefit many connector designs and applications, it is particularly beneficial when applied to hands free connectors for charging electric vehicles—also known in the industry as the Electric Vehicle Charge Couplers. The specific geometry taught in the patent satisfies the requirements of register-free connectors such as not to be able to short circuit supply conductors, provide at least one drain side conductor for every supply side conductor, permit easy sliding between supply and drain side conductors and provide at least one drain side contact with its centerline to overlap each supply side contact. Additional treads on the contacts provide self-cleaning ability without disturbing the register-free functionality by providing a path for loose dirt and oxides to escape, while the ridges between the grooves break the dirt into small pieces. The groove pitch is adjusted in relation to the sliding distance between the contacts such that every broken down piece of the dirt finds an escape path. |
US08573981B2 |
Training system for an article of footwear with a ball control portion
A training system for an article of footwear is disclosed. The training system includes a method of training an athlete to use an article of footwear with a ball control portion to help enhance accuracy when kicking a ball. The method can be implemented on a computer, mobile device or as an instruction booklet. The training system provides a total training solution for an athlete that is designed to enhance specific athletic skills. |
US08573980B2 |
Apparatus, system, and method for modulating consolidation of memory during sleep
Devices, systems and methods to modify memory and/or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement/relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep. |
US08573978B2 |
Driving evaluation system and driving evaluation method
Systems, method, and programs evaluate a driving condition of a vehicle in accordance with road characteristic information that is included in map data, acquire evaluation information that includes an evaluation result based on the evaluation, and store the evaluation information. The systems, methods, and programs acquire update data to change the road characteristic information included in the map data, update the map data, and analyze the evaluation result for the evaluation information acquired during the period between the time when a road characteristic is modified and the time when the map data is updated, based on the changed road characteristic information included in the updated map data. |
US08573975B2 |
Beam shaping for off-axis beam detection in training environments
A firing apparatus includes a light generating device for emitting a modulated light beam that includes information regarding the firing apparatus upon triggering in a direction toward a target. Lens optics is positioned in a path of the modulated light beam including a one dimensional lens for beam shaping the modulated light beam to provide a shaped modulated beam including a low divergence horizontal beam portion and a vertically elongated beam portion. A combat training system includes a head mounted apparatus including at least one photodetector affixed. The vertically elongated beam portion allows the light beam generated by the firing apparatus to be aimed at the torso of the target and be detected by photodetectors that are exclusively on the helmet. |
US08573971B2 |
Orthodontic bracket with frangible cover mechanism
An orthodontic bracket is provided that includes a cover and a base, wherein the cover can be rotated over an arch wire slot in the base portion. The present bracket invention operates to close when a frangible portion is severed upon initiating rotation of the cover, such that the cover rotates about a hinge, which may include a pin or axle. In one embodiment of the invention, the pin or axle can be moved laterally and/or vertically after the frangible portion is severed. Preferably, the bracket is manufactured to form one piece, such as using an injection molding, machining, or casting process. The bracket offers economical advantages because additional subsequent assembly is not required to attach a cover to a base. |
US08573970B2 |
Dental prosthesis for bovine animals with fully or partially worn down teeth
A dental prosthesis for bovine animals with fully or partially worn down teeth. For bovine animals with partially worn down teeth, the prosthesis is a laminar plate of a rigid material, bent forwards, with an upward fold having a sawn edge along its front curve connected to a lower laminate of the same shape and size, from which a tongue projects downwards into the central front zone, at the end of which two small laminates are folded, and in the rear, a tongue projects behind, and divides into two, thereby creating a fold towards the front and encompassing two wires in the transverse direction, the ends of which are housed in the front laminates. For bovine animals with fully worn down teeth, the laminar plates have a downwardly inclined fold along the entire front curve thereof. |
US08573969B2 |
Silicon wafer heat treatment method
A silicon wafer preferable to a semiconductor device is produced by determining a heat treatment condition hardly causing slip dislocations and heat-treating the silicon wafer under the condition. The resistance is calculated by using a calculation formula used for predicting the slip resistance of the wafer from the density, size, and residual solid-solution oxygen concentration of the oxygen precipitation in the silicon wafer, the state of oxygen precipitation such that heat treatment not causing any slip dislocation can be carried out is designed, and thus a silicon wafer heat treatment method under the heat treatment condition not causing any slip dislocation is determined. A silicon wafer heat-treated under such a condition can be provided. |
US08573963B2 |
Adjustable multiple-piece cam track
A multiple-piece cam unit for use in a molding machine. The cam unit has a cam track which engages cam followers of mold assemblies of the molding machine to move the cam followers between a first position and a second position. The cam unit includes a first cam section and a second cam section. The first cam section has an entrance portion which is dimensioned to receive the cam followers therein. The second cam section has an exit portion positioned to release the cam followers therefrom. The second cam section is moveably mounted to the molding machine to allow the exit portion of the second cam section to be moved relative to the entrance portion of the first cam section, to insure that the cam followers exiting the exit portion of the second cam section are properly aligned to enter the entrance portion of the first cam section. |
US08573961B2 |
Mold for manufacturing a foldable artificial vitreous body
The present invention relates to a foldable capsular vitreous body (FCVB), and its mold design, method for manufacturing, product appearance, and drug delivery property and so on. A mold for molding a foldable artificial vitreous body comprises an upper mold (1), a lower mold (2) and a core (3). The core (3) is disposed between the upper mold (1) and the lower mold (2) and is connected with a drainage-tube pin connected with an injection channel (4). Heating holes (6) are disposed in the upper mold (1) and/or the lower mold (2). Material is injected to the mold and is heated to vulcanize to mold vitreous body. The FCVB is adapted to be injected with any harmless medium and can be used as a delivery vehicle inside or around the eye ball. The size or shape of the FCVB can be changed depending on the different implant site. |
US08573959B2 |
Rotary spinning electrode
The rotary spinning electrode of elongated shape, serving to carry polymer solution from reservoir of polymer solution or melt into electric field for spinning in devices for production of nanofibers through electrostatic spinning of polymer solutions or melts, including a pair of end faces (2, 3), which are arranged on the carrying mean (1), and between which are mounted the spinning members (41, 42, 43, 44, 45, 46), which are formed of a cord or wire (4). The spinning members (41, 42, 43, 44, 45, 46) are in a skew position to an axis (11) of rotation of the rotary spinning electrode. |
US08573955B2 |
Scroll compressor with noise reducing discharge opening
A scroll compressor is provided that includes a hermetic container into and out of which a refrigerant flows, a driving device installed in the hermetic container to rotate a rotation axis, an orbiting scroll fixed to the rotation axis and rotated with the rotation axis, and a fixed scroll fixed to the hermetic container and engaged with the orbiting scroll to define a compression chamber, in which the refrigerant is compressed, by an interaction with the orbiting scroll. A discharge hole of the fixed scroll comprises a discharge inlet portion through which high pressure refrigerant flows in, a discharge outlet portion through which the high pressure refrigerant flows out, the discharge outlet portion being eccentric to the discharge inlet portion, and a bottleneck section through which the discharge inlet portion and the discharge outlet portion communicate with each other. The scroll compressor reduces pulsation noise of the refrigerant to improve noise performance. |
US08573954B2 |
Fan assembly
A fan assembly including a rotation shaft, a permanent magnet having a receiving space therein and rotatable around a central axis of the rotation shaft, a fan including a hub having a receiving space therein with one side open and disposed outside the permanent magnet, the fan being rotatable around the central axis of the rotation shaft, a stator disposed inside the permanent magnet, and a blocking portion disposed at the open side of the hub in an axial direction, the combination configured to block an introduction of foreign materials into the fan assembly and to reduce the size of the fan assembly. |
US08573951B1 |
Pool recirculation pump safety system and method
A pool recirculation pump safety system includes a power supply assembly operable to selectively supply operating power to a recirculation pump motor, an entrapment detection assembly operable to detect a change in a recirculation system parameter indicative of swimmer entrapment at a suction intake opening, and a timer assembly operable to automatically bypass the entrapment detection assembly for a predetermined time period upon energization of the system. During operation of the recirculation pump motor, the system is configured to secure operating power to the recirculation pump motor upon detection of the indicative recirculation system parameter change after the predetermined time period. The entrapment detection assembly and the timer assembly can be arranged to form a switchable neutral connection for a power relay of the power supply assembly. |
US08573950B2 |
Tower internal-equipment bracket structure and wind turbine generator
A tower-internal-equipment bracket structure with a welded structure that can ensure a fatigue strength classification equal to or greater than that of butt welding (BW) or that requires no welding and a wind turbine generator provided with this tower-internal-equipment bracket structure are provided. In a tower-internal-equipment bracket structure provided inside a pole-type steel tower, employing a cylindrical shell (11), to support tower internal equipment, a ring-shaped member (20) having a protruding portion (21) toward the tower interior is interposed, by means of butt welding (BW), between divided portions formed by dividing the cylindrical shell (11) at a desired position in an axial direction, and the protruding portion (21) serves as a bracket-member support portion for the tower internal equipment. |
US08573946B2 |
Compressor blade
A blade for a compressor having a pressure surface and a suction surface. The suction surface includes a discontinuity in the chord-wise curvature of an intermediate portion of the suction surface between the blade leading edge and blade trailing edge, and a slot arranged along at least a portion of the blade in a substantially span-wise direction. The slot being disposed at or near the change in curvature, such that when in use lower momentum fluid near the suction surface is aspirated into the slot. |
US08573943B2 |
Gas turbine having sealing plates on the turbine disc
A turbine rotor having a plurality of rotor blades assembled into rotor blade rows and arranged on a turbine disk is provided. The respective turbine disc on the side surfaces thereof includes a plurality of sealing plates having edges that are arranged radially towards the inside, enables a simplified design and assembly, while maintaining maximum operational reliability and maximum efficiency of a turbine equipped therewith. Therefore, between the edge of the respective sealing plate and a side wall of the turbine disc groove, a closure member is provided, wherein the edge extends over the entire azimuthal length of the sealing plate and the closure members abut each other in the azimuthal direction for sealing purposes. The closure members may be inserted into the turbine disc groove via a recess interrupting the respective edge and extending substantially azimuthally on the side facing the turbine axis. |
US08573941B2 |
Tandem blade design
A tandem blade design for an axial turbomachine, comprising a front blade and a rear blade disposed with an offset thereto in the circumferential direction and in the axial direction. The rear blade is profiled and positioned with respect to the front blade such that it raises the speed level at the trailing edge of the front blade in a predetermined working range in interaction with the front blade. |
US08573939B2 |
Shroud for rotating blades of a turbo machine, and turbo machine
A shroud for the rotating blades of a turbo machine, particularly a gas turbine, in which shroud is arranged along the circumference of a row of several rotating blades disposed on a rotor and has at least one separation gap along its circumference. The separation gap is formed in zigzag shape and has at least three damping gaps that are distanced from one another and extend at an angle relative to an axis of rotation of the rotor, and adjacent to these, has connection gaps each connecting damping gaps or extending the latter in the direction of shroud edges, wherein, when the rotor rotates, the gap width of damping gaps is reduced until the gap walls forming the damping gaps come to rest against each other. |
US08573932B2 |
Compressor blade root heating system
The compressor blade root heating system may be formed from one or more induction heaters formed from one or more induction coils positioned in close proximity to a root of a compressor blade. In one embodiment, the induction heater may be coupled to a static casing component positioned immediately upstream of a first row of compressor blades on a rotor assembly such that the induction heater is stationary during turbine engine operation. The induction heater causes eddy current formation, which heats the row one compressor blades. This heating increases the fracture toughness of the material forming the rotor and compressor blades, thereby increasing the mechanical life cycle. |
US08573930B2 |
Nozzle assembly of variable geometry turbocharger
According to the present invention, it is possible to achieve improved durability by improving the connection structure of operation links and a control ring to reduce friction and wear between the operation links and the control ring, facilitate manufacturing by simple configuration and structure, and achieve silent and stable operation by making it possible to set the gaps between the parts relatively small. |
US08573929B2 |
Turbocharger with turbine nozzle vanes and an annular rotary bypass valve
A turbocharger includes an annular bypass passage to allow exhaust gas to bypass the turbine wheel. An annular bypass valve is disposed in the bypass passage. The bypass valve comprises a fixed annular valve seat and a rotary annular valve member arranged coaxially with the valve seat. The valve member is disposed against the valve seat and is rotatable about the axis for selectively varying a degree of alignment between respective orifices in the valve seat and valve member. The turbine includes a nozzle having a vane assembly. In one embodiment the vane assembly has only fixed vanes. In another embodiment the vane assembly includes both fixed vanes and variable vanes, and the variable vanes are part of a rotor that rotates together with the rotary valve member. |
US08573928B2 |
Coupling device intended to connect first and second elements which can move relative to one another
The invention relates to a coupling device (14) intended to connect first and second elements (4, 5) which can move relative to one another, comprising a connecting rod (16) coupled to the first and second movable elements (4, 5) at first and second ends (18, 19) respectively, at least one of the ends of the connecting rod (16) having a head (22) intended to cooperate with locking means (23) belonging to the corresponding movable element (5) so as to removably fasten the connecting rod (16) to the corresponding movable element (5), characterized in that the coupling device (14, 15) comprises at least one telescopic guide member (25) serving to support and guide the connecting rod (16) during the movement of the movable elements (4, 5), having first and second ends (28, 26) intended to be attached to first and second support elements (23, 16) respectively. |
US08573925B2 |
Cooled component for a gas turbine engine
A cooled component for a gas turbine engine, the component includes a segment region defining a segment of an annulus for passage of hot gases therethrough, the segment region having a pair of opposed side faces configured to lie substantially adjacent respective corresponding side faces of segments of similar operationally and circumferentially adjacent components, wherein: the segment region includes an elongate cooling slot in at least one of the side faces, the cooling slot being arranged in fluid communication with at least one flow passage within the segment region for a supply of cooling fluid to the slot, and the slot is substantially closed at an upstream end of the slot and open at a downstream end of the slot so as to define an outlet for the cooling fluid at an operationally downstream region of the at least one of the side faces. |
US08573921B2 |
Method and a device for lifting and rotating a massive container
A device and method for lifting and rotating a massive container comprising a base frame assembly, a cradle pivotally connected to the base frame assembly and adapted to hold the container, a mechanism for moving the container vertically relative to at least part of the base frame assembly, and a hydraulic cylinder connected between the base frame assembly and the cradle for rotating in a vertical plane the cradle relative to the base frame assembly. |
US08573919B2 |
Substrate transport apparatus
A substrate transport apparatus having a frame, a drive section and an articulated arm. The drive section has at least one motor module that is selectable for placement in the drive section from a number of different interchangeable motor modules. Each having a different predetermined characteristic. The articulated arm has articulated joints. The arm is connected to the drive section for articulation. The arm has a selectable configuration selectable from a number of different arm configurations each having a predetermined configuration characteristic. The selection of the arm configuration is effected by selection of the at least one motor module for placement in the drive section. |
US08573918B2 |
Dual mode end effector
A dual mode end effector is disclosed. The dual mode end effector includes a bridge member having a first end and a second end, wherein the bridge member includes a first substantially axial flange extending from the first and, wherein the bridge member includes a second substantially axial flange extending from the second end; a tire/wheel gripping assembly connected to the bridge member, wherein the tire/wheel gripping assembly includes a pair of substantially axial members, a substantially radial support member, and a pair of radially-projecting engaging assemblies, wherein the pair of substantially axial members are movably-supported upon the substantially radial support member, wherein a first end of the substantially radial support member is connected to the first substantially axial flange of the bridge member, wherein the a second end of the substantially radial support member is connected to the second substantially axial flange of the bridge member, wherein a first radially-projecting engaging assembly of the pair of radially-projecting engaging assemblies is connected to an inner radial surface of a first substantially axial member of the pair of substantially axial members, wherein a second radially-projecting engaging assembly of the pair of radially-projecting engaging assemblies is connected to an inner radial surface of a second substantially axial member of the pair of substantially axial members. |
US08573916B2 |
Trailer for helicopter
A trailer is provided for a helicopter. The trailer includes a chassis, at least two lifters provided on the chassis, at least two drivers provided on the chassis and connected to the lifters, at least two locks for locking the lifters in an upper position and a connector for connecting the chassis to a vehicle. |
US08573911B2 |
Floating fasteners
One or more fastenings can be used to fasten components together, such as housing components on a computing device. Each fastening can include a first opening associated with a first component, a second opening associated with a second component, a floating fastener, and a screw. The floating fastener is inserted into the first opening and/or second opening, and includes a threaded opening therein having a primary axis therethrough. The screw is inserted through first and/or second openings and into the threaded opening in the floating fastener. The screw and threaded opening combination is defined by contact between the screw and threaded opening about a thread surface that is substantially perpendicular to the primary axis, a screw thread return angle of 45 degrees or less, and a thread depth that is less than about triple the float between the major diameters of the screw and the threaded opening. |
US08573908B2 |
Machining center including a control board arranged side by side with an operator door
A machining center wherein improved workability of a control board, a widened movable zone of a column and a reduced installation space are achieved. The machining center includes a column movably supported on a column sliding portion in an X-axis direction, a work table movably supported on a table sliding portion in a Z-axis direction, a main spindle head slidably supported on the column in a Y-axis direction, and an automatic tool changer disposed at an inner side of the column sliding portion. The control board is arranged at an opposite side of the automatic tool changer and is provided in parallel with a side surface of a front portion of a table sliding portion and is arranged side by side with an openable/closable door for an operator provided on a side surface of a cover in a vicinity of a rear end portion of the side surface of the table sliding portion. |
US08573907B2 |
Hole cutter with minimum tooth pitch to blade body thickness ratio
A hole cutter for cutting a work piece, such as a wood and/or metal work piece, has a substantially cylindrical blade body defining a wall thickness within the range of about 0.032 inch to about 0.038 inch, and a cutting edge formed on one end of the blade body including a plurality of teeth defining an average tooth pitch within the range of about 3.5 TPI to about 5.5 TPI for cutting the work piece and forming chips therefrom. The substantially cylindrical blade body and cutting edge define an average tooth pitch to blade body thickness ratio of at least about 110. |
US08573906B2 |
Drill guide apparatus
This invention relates to a drill guide apparatus for use in drilling holes in wood and other material in conjunction with spade drills. When deeper holes are required, the invention will also utilize drill extension rods. The embodiment consists of 4 separate guides assembled together which make a hole as parallel and perpendicular as possible to the work piece. One of these guides, the insert guide, acts as a stabilizer that helps keep the drill from drifting and wobbling. The guide shaft lines up with the work piece and starts the parallel course. When the spacer and base plate lay up against the work piece, the spade drill will travel in a perpendicular course. The spade drill and drill extension rod are prior art and are readily available in the market place. |
US08573904B2 |
Grooving insert
A cutting insert having a base portion structured to be coupled to a tool body, the base portion having a leading end, a trailing end, and a mounting face extending therebetween. A number of cutting portions extend from the base portion opposite the mounting face. Each cutting portion of the number of cutting portions includes a cutting face disposed adjacent the leading end of the base. The cutting face having an angled portion disposed at a first angle with respect to a reference plane oriented parallel to the leading end and perpendicular to the mounting face. The cutting face also having a curved portion disposed between the angled portion and the base portion. |