| Document | Document Title |
|---|---|
| US08563700B2 |
Synergistic effects
The present invention encompasses a combination of at least one conjugate and one or more chemotherapeutic agent(s) which when administered exerts an unexpectedly enhanced therapeutic effect. The therapeutic effectiveness of the combination is greater than that of the conjugate alone or the administration of one or more of the drug(s) without the conjugate. The present invention is also directed to compositions comprising at least one conjugate and at one or more of chemotherapeutic agent and to methods of treating cancer using at least one conjugate and at least one or more of chemotherapeutic agent(s). The present invention also provides methods of modulating the growth of selected cell populations, such as cancer cells, by administering a therapeutically effective amount of one or more chemotherapeutic agent(s) and at least one conjugate. In each case, such combination has therapeutic synergy or improves the therapeutic index in the treatment of cancer over the anticancer agent(s) alone. |
| US08563699B2 |
Anthrax and small Pox replikins and methods of use
Isolated peptides of the Bacillus anthracis Anthrax Toxin Lethal factor Protein pX01-107, antibodies specific for the peptides and methods of stimulating the immune response of a subject to produce antibodies to the Bacillus anthracis Anthrax Toxin Lethal factor Protein pX01-107 are disclosed. Also disclosed are isolated peptides of the Small Pox Virus Surface Antigen S Precursor Protein, antibodies specific for the peptides and methods of stimulating the immune response of a subject to produce antibodies to the Small Pox Virus Surface Antigen S Precursor Protein. |
| US08563695B2 |
Antibodies that bind β2
Compositions and methods are provided for the classification, diagnosis, treatment, and prevention of tumors characterized by loss of REST function, expression of β2, and/or activation of Notch. Further compositions and methods are provided for modulation of cellular processes such as EMT, cell migration, and apoptosis. |
| US08563689B1 |
Methods for regulating inflammatory mediators and peptides for useful therein
The present invention includes methods of modulating cellular secretory processes. More specifically the present invention relates to modulating or reducing the release of inflammatory mediators from inflammatory cells by inhibiting the mechanism associated with the release of inflammatory mediators from the vesicles or granules in the inflammatory cells in a subject with a chronic inflammatory disease. In this regard, the present invention discloses an intracellular signaling mechanism that illustrates several novel intracellular targets for pharmacological intervention in disorders involving secretion of inflammatory mediators from vesicles in inflammatory cells. MANS peptide and active fragments thereof are useful in such methods. |
| US08563687B2 |
Synthetic genes for plant gums and other hydroxyproline rich glycoproteins
A new approach in the field of plant gums is described which presents a new solution to the production of hydroxyproline(Hyp)-rich glycoproteins (HRGPs), repetitive proline-rich proteins (RPRPs) and arabino-galactan proteins (AGPs). The expression of synthetic genes designed from repetitive peptide sequences of such glycoproteins, including the peptide sequences of gum arabic glycoprotein (GAGP), is taught in host cells, including plant host cells. |
| US08563686B2 |
Conformationally constrained peptide mimetics
Conformationally constrained peptide mimetics in which a hydrogen bond interaction is replaced with a covalent hydrogen bond mimic are provided. Also provided are various methods of making these peptide mimetics. |
| US08563685B2 |
Fatty acid formulations and oral delivery of proteins and peptides, and uses thereof
Fatty acid compositions for administration of of pharmaceutical agents, such as proteins and peptides, protein and peptide conjugates, and/or cation-polypeptide conjugate complexes. In particular, the invention provides a solid pharmaceutical composition formulated for oral administration by ingestion, having from about 0.1 to about 75% w/w fatty acid component, where the fatty acid component comprises saturated or unsaturated C4, C5, C6, C7, C8, C9, C10, C11, or C12 fatty acids and/or salts of such fatty acids; and a therapeutic agent. Further, the invention provides a liquid pharmaceutical composition formulated for oral administration by ingestion, comprising: from about 0.1 to about 10% w/v fatty acid component, where the fatty acid component comprises saturated or unsaturated C4, C5, C6, C7, C8, C9, C10, C11, or C12 fatty acids and/or salts of such fatty acids; and a therapeutic agent. |
| US08563684B2 |
Tumor antigen protein SART-3 and tumor antigen peptides thereof
A novel tumor antigen protein and gene therefor, tumor antigen peptides derived from said tumor antigen protein or derivatives thereof as well as medicaments, prophylactics, or diagnostics for tumors using such tumor substances in vitro or in vitro are provided. |
| US08563677B2 |
Non-precipitating alkali/alkaline earth metal and aluminum solutions made with diols having at least two primary hydroxyl groups
A stable catalyst solution suitable for catalyzing the polycondensation of reactants to make polyester polymers comprising: (i) M, wherein M is represented by an alkaline earth metal or alkali metal and (ii) aluminum metal and (iii) a polyhydroxyl solvent having at least 3 carbon atoms and at least two primary hydroxyl groups, the longest carbon chain being a hydrocarbon; such as 1,3-propane diol, 1,4-butane diol, 1,5-pentane diol, or combinations thereof, wherein the molar ratio of M:Al ranges from 0.75:1 to less than 1.5:1. The catalyst solution is desirably a solution which does not precipitate upon standing over a period of at least one week at room temperature (25° C.-40° C.), even at molar ratios of M:Al approaching 1:1. There is also provided a method for the manufacture of the solution, its feed to and use in the manufacture of a polyester polymer, and polyester polymers obtained by combining certain ingredients or containing the residues of these ingredients in the composition. |
| US08563676B2 |
Reactive amine catalysts for polyurethane foam
Polyurethanes made using compounds of formula A: Q-(R6)-M-(R7)-NR3R4 where Q is OH or NR1R2; M is O or NR5 where R5 is R1 or H; R1 is alkyl or an alkylene alcohol of from 1 to 6 carbons, especially CH3, CH2CH3, or CH2CH2OH; R2 is alkyl or an alkylene alcohol of from 1 to 6 carbons, especially CH3, CH2CH3, or —CH2CH2OH; R3 is hydrogen or alkyl of from 1 to 6 carbons, especially H, CH3 or CH2CH3; R4 is hydrogen; where R6 is an alkylene group of from 2 to 5 carbons; and wherein R7 is an alkylene group of from 2 to 5 carbons. Illustrative catalysts of this invention include but are not limited to N,N,N′-trimethylbis(aminoethyl)ether, dimethylaminoethoxypropylamine, and (3-aminopropyl)(2-hydroxyethyl)methylamine. |
| US08563675B2 |
Curable compositions composed of silanes with two hydrolyzable groups
The present invention relates to silane-crosslinking curable compositions encompassing a polymer P having at least two terminal groups of the following formulas (I) and (II) -Am-K1—SiR1XY (I), -Am-K2—SiR2XY (II), and/or two polymers P1 and P2, polymer P1 having terminal groups of the following formula (I) -Am-K1—SiR1XY (I), and polymer P2 having terminal groups of the following formula (II) -Am-K2—SiR2XY (II), in which A denotes a divalent bonding group, K1, K2, mutually independently, denote a divalent aliphatic hydrocarbon group that has a main chain of 1 to 6 carbon atoms, the hydrocarbon groups K1, K2 being different, X, Y mutually independently denote a hydroxy group or a hydrolyzable group, R1, R2 mutually independently denote a hydrocarbon residue having 1 to 20 carbon atoms, and m assumes the values 0 or 1. |
| US08563673B2 |
Propylene-based resin molded article and method for producing the same
A propylene-based resin molded article satisfying the following requirements (1) through (4): Requirement (1) Lc/La≦1.50 Requirement (2) Lc≧10.0 Requirement (3) F1≧0.07 Requirement (4) F2≧0.06 wherein in Requirements (1) through (4), La denotes the distance (unit: nm) between crystalline lamellae calculated from the long-period distance calculated from a small-angle X-ray scattering profile and the degree of crystallization calculated from the amount of heat of fusion measured by differential scanning calorimetry, Lc denotes the thickness (unit: nm) of a crystalline lamella calculated from the distance between crystalline lamellae and the long-period distance, F1 denotes the degree of orientation calculated from the infrared dichroic ratio measured at a wave number of 997 cm−1, and F2 denotes the degree of orientation calculated from the infrared dichroic ratio measured at a wave number of 973 cm−1. |
| US08563672B2 |
Process for producing fluorinated copolymers of (meth)acrylates and (meth)acrylic acid amine complexes
A process for producing copolymers of (meth)acrylates:(meth)acrylic acid amine complexes useful for hard surfaces having increased performance for stain resistance, oil and water repellency properties. |
| US08563664B2 |
Crosslinkable biopolymer
A composition, prepolymer and method to produce a polymer based on biodegradable or essentially renewable crude materials, which can be crosslinked by free radicals. The composition is based on polyesters that are functionalized with unsaturated monomer units, in a way that unsaturated groups can be located along the polymer main chain as well as at the ends of the prepolymer. In connection to the product production, the prepolymer is exposed to free radicals that leads to network formation. The composition of the crosslinked biopolymer can be adjusted from a stiff engineering material to an elastic rubbery material. The new biopolymer can be used in composite materials, dispersions, barrier materials, rubbery materials, biomedical applications, and the like. |
| US08563663B2 |
Heat curable composition for composite parts and intumescent coatings
The invention relates to a heat curable composition for fire-resistant or intumescent composite parts, which is free of any halogen additive or halogen structure in the components thereof, and which comprises: a) 100 parts by weight of a dry resin, including a1) an unsaturated polyester having an acid index lower than 10 and/or a2) a vinyl ester; b) 40 to 200 parts by weight of a reactive thinner among ethylenically unsaturated monomers; c) 20 to 110 parts by weight of a thermal expansion agent selected from melamine and derivatives thereof, guanidine, glycine, urea, triisiocynurates, and azodicarbinamide; d) 0 to 250 parts by weight of aluminium trihydrate; e) 10 to 80 parts by weight of a carbonisation precursor agent selected from multifunctional polyols; f) 50 to 200 parts by weight of a compound selected from a phosphorus derivative and/or a boric acid derivative; g) optionally at least one metal oxide; h) optionally other additives and fillers; i) optionally reinforcements containing natural or synthetic fibres and related fabrics, wherein the acid component of the polyester a1) contains at least 60 mol % of acid and/or maleic anhydride and the polyol component contains at least 70 mol % of propylene glycol. The compositions can be used in the field of transport, building, public works, civil engineering and recreation or street furniture with intumescent composite parts or coatings that comply at least with criterion HL2 of the R1 requirement of prCEN/TS 45545-2:2008. |
| US08563660B2 |
Fluororubber-based sealing material having good sealing properties under high/low temperature load
[Object] To provide a fluororubber-based sealing material which is excellent in sealing properties under high/low temperature load and is capable of sealing at a temperature of not higher than −40° C. even when gas oil (diesel fuel) is used.[Means for Solving] A fluororubber-based sealing material obtained by crosslinking a composition for a fluororubber-based sealing material, said composition comprising 100 parts by weight of a fluorine-containing copolymer which contains 64 to 69% by weight of fluorine, has a crosslinking site derived from a bromine-containing compound and/or an iodine-containing compound and is capable of being crosslinked by a peroxide, 0.5 to 6 parts by weight of an organic peroxide and 1 to 10 parts by weight of a polyfunctional monomer, wherein the fluorine-containing copolymer in the composition for a fluororubber-based sealing material is a fluororubber polymer obtained by copolymerizing (a) VDF, (b) TFE, (c) FMVE, (d) FMMVE and (e) brominated/iodinated unsaturated fluorohydrocarbon. |
| US08563643B2 |
Method for manufacturing a coating slip, using an acrylic thickener with a branched hydrophobic chain, and the slip obtained
The invention consists of a method for manufacturing a paper coating slip containing a mineral material, using, as an agent for thickening the slip, a water-soluble polymer comprising at least one ethylene-unsaturated anionic monomer, and at least one ethylene-unsaturated oxyalkyl monomer terminating in a branched hydrophobic alkyl, alkaryl, arylalkyl, aryl chain, saturated or unsaturated, with 14 to 21 carbon atoms and two branches each with at least six carbon atoms. The polymer is added to the slip either directly, or during a prior stage when grinding, dispersing, or concentrating the mineral material in water, which may or not be followed by a drying stage. In this way, the water retention of the slip is improved, which contributes to a better printability of the paper coated by the slip. |
| US08563642B2 |
Process for dry grinding of one or more mineral materials including at least one calcium carbonate
The present invention provides a process for dry grinding one or more mineral materials which include at least calcium carbonate. The process includes a) crushing the mineral material or materials in at least one crushing unit until a crushed material is obtained with a d95 of less than 10 cm, and dry grinding the material in at least one grinding unit (i) in the presence of at least one comb-type hydrophilic polymer containing at least polyalkylene oxide function grafted on to at least one unsaturated ethylene monomer, and (ii) in such a manner that the quantity of liquid in the grinding unit is less than 15% by dry weight of the material crushed in the crushing unit, wherein recovered material has a d50 of 0.5 to 500 microns. |
| US08563638B2 |
Oligomeric phosphonates and compositions including the same
Disclosed are oligomeric phosphonates including oligophosphonates, random or block co-oligo(phosphonate ester)s and co-oligo(phosphonate carbonate)s produced using a condensation process terminated with hydroxyl, epoxy, vinyl, vinyl ester, isopropenyl, isocyanate groups, and the like. These materials can be used as a reactive additive to other polymers, oligomers or monomer mixtures to impart flame resistance without diminishing melt processability which is important in the fabrication of polymers for many applications. |
| US08563637B2 |
Alkylphenol free-liquid polymeric phosphite polymer stabilizers
An alkylphenol-free liquid polymeric phosphite is described of general Structure IV illustrated below wherein each R1, R2, R3 and R4 can be the same or different and independently selected from the group consisting of C1-20 alkyl, C3-22 alkenyl, C6-40 cycloalkyl, C7-40 cycloalkylene, C1-20 methoxy alkyl glycol ethers, C1-20 alkyl glycol ethers, and or Y—OH; Y is selected from the group consisting of C2-40 alkylene, C2-40 alkyl lactone, —R7—N(R8)—R9—, wherein R7, R8 and R9 are independently selected from the group previously defined for R1, R2, R3 and R4, now further including H; m is an integral value ranging from 2 to 100 inclusive; and x is an integral value ranging from 1 to 1,000. The alkylphenol-free liquid polymeric phosphite is useful in reducing phosphite migration within polymers. |
| US08563627B2 |
Self emulsifying granules and process for the preparation of emulsions therefrom
A process for making a self-emulsifying granule suitable for use in forming latex emulsions includes contacting a resin with a solid or highly concentrated surfactant, a solid neutralization agent and water in the absence of an organic solvent to form a mixture, melt mixing the mixture, and forming self-emulsifying granules of the melt mixed mixture. Self-emulsifying granules are also provided and configured to form a latex emulsion when added to water, which may then be utilized to form a toner. |
| US08563626B2 |
Use of plasma-synthesised pyrrole-derived polymers for the neuroprotection and reconnection of the central nervous system
The purpose of the present invention is to demonstrate that semiconducting and non-biodegradable implants made with polypyrrole and polyethylenglycol copolymers and iodine-doped and plasma-synthesized pyrrole polymers, have a neuroprotector effect and induce the reconnection of the spinal cord after an injury; this effect was proved in a model involving a complete section of the spinal cord in rats; the results o the functional evaluation demonstrated 5 times greater recovery in animals implanted with the polypyrrole-polyethylenglycol copolymer compared with the control group which only underwent a complete section of the spinal cord; in addition, the functional recovery of the group with iodine-doped polypyrrole was ten times greater compared to the control group; in the histological study various inflammatory and immune cells were identified at the injury site in the three experimental groups with and without implants and the integration of the polymers in the nervous tissue of the spinal cord was also observed; finally, no respiratory, renal or skin infections, adverse effects or rejection of the biomaterials were found in any of the animals. |
| US08563619B2 |
Methods and arrangements for plasma processing system with tunable capacitance
A method for processing a substrate in a plasma processing chamber is provided. The substrate is disposed above a chuck and surrounded by an edge ring. The edge ring is electrically isolated from the chuck. The method includes providing RF power to the chuck. The method also includes providing a tunable capacitance arrangement. The tunable capacitance arrangement is coupled to the edge ring to provide RF coupling to the edge ring, resulting in the edge ring having an edge ring potential. The method further includes generating a plasma within the plasma processing chamber to process the substrate. The substrate is processed while the tunable capacitance arrangement is configured to cause the edge ring potential to be dynamically tunable to a DC potential of the substrate while processing the substrate. |
| US08563617B2 |
Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy
The present invention relates to aminotetraline derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminotetraline derivatives, and the use of such aminotetraline derivatives for therapeutic purposes. The aminotetraline derivatives are GlyT1 inhibitors. |
| US08563615B2 |
Use of CI-994 and dinaline for the treatment of memory/cognition and anxiety disorders
The invention relates to methods and compositions for promoting cognitive function and/or treating cognitive function disorders and impairments. In particular the methods are accomplished by administering to a subject CI-994 or dinaline or a pharmaceutically acceptable salt, ester, prodrug or metabolite thereof. |
| US08563614B2 |
Use of treprostinil to treat neuropathic diabetic foot ulcers
The present invention describes novel methods for using 9-deoxy-2′,9-α-methano-3-oxa-4,5,6-trinor-3,7-(1′,3′-interphenylene)-13,14-dihydro-prostaglandin F1 (also known as Treprostinil) or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of foot ulcers in subjects with diabetic neuropathy. The invention also relates to kits for treatment and/or prevention of foot ulcers, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof. |
| US08563613B2 |
Diclofenac topical formulation
The present invention provides a gel formulation comprising diclofenac sodium which has superior transdermal flux properties, which may be used for the topical treatment of pain, such as in osteoarthritis. |
| US08563610B2 |
Polyunsaturated fatty acids interactions and oxidative stress disorders
This invention relates to the identification and treatment of the effects of products derived from oxidative pathways for polyunsaturated fatty acid (PUFA) metabolism, i.e., oxidative stress in a patient by monitoring the metabolism of DHA or by administering DHA. |
| US08563609B2 |
Nitro fatty acids - neuroprotection and/or inhibition of cognitive decline
A composition for treating, ameliorating and/or preventing conditions associated with cognitive decline and/or motor neuron death comprise a fatty acid component enriched for one or more activated fatty acids and a nutraceutically acceptable excipient. A method for treating, ameliorating and/or preventing conditions associated with cognitive decline and/or motor neuron death includes administering a fatty acid component enriched for one or more activated fatty acids. |
| US08563607B2 |
Polyphenol proteasome inhibitors, synthesis, and methods of use
The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers. |
| US08563605B2 |
Therapeutic agent for male sterility
The present invention is intended to provide an agent for treating male infertility which is highly effective to male infertility, and having few side effects. To achieve the object, an agent for treating male infertility comprising δ-amino levulinic acid shown by general formula (1), its derivative or salt thereof: R2R1NCH2COCH2CH2COR3 (1) [wherein R1 and R2 independently represent a hydrogen atom, alkyl group, acyl group, alkoxycarbonyl group, aryl group, or aralkyl group; R3 represents a hydroxy group, alkoxy group, acyloxy group, alkoxycarbonyloxy group, aryloxy group, aralkyloxy group or amino group] can be used. |
| US08563604B2 |
Silicone gel-based compositions for wound healing and scar reduction
This invention is a composition comprising a cyclic siloxane, a silicone occlusive fluid, a silicone occlusive gel, and a silicone resin powder. The composition is useful for wound healing. |
| US08563601B2 |
Method of managing broncho-constrictive condition
The present disclosure is in relation to the use of a composition comprising pentameric type A procyanidin, trimeric procyanidin and tetrameric procyanidin, optionally along with pharmaceutical excipient(s), in management of broncho-constrictive conditions such as Allergic Rhinitis, Asthma, and Chronic obstructive pulmonary disease (COPD). |
| US08563597B2 |
Fused tricyclic ether carbamates and their use
Tricylic ether carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are described. Methods of using the disclosed compounds for treating patients infected with HIV are also described. |
| US08563596B2 |
Enantiomerically pure compounds for the treatment of proliferative disorders
The present invention relates to an enantiomerically pure (+)-trans enantiomer of a compound represented by the following formula (I): wherein R1, R2, R3, R4 and R9 are as defined in the specification; enantiomerically pure intermediates thereof, to processes for the preparation of the enantiomerically pure compound and its intermediates, and to a pharmaceutical composition comprising the enantiomerically pure compound. The compound of formula (I) is useful for the treatment of diseases or disorders mediated by the inhibition of cyclin dependant kinase, such as cancer. |
| US08563593B2 |
Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
The present invention relates to formulations of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), pharmaceutical packs or kits thereof, and methods of treatment therewith. |
| US08563590B2 |
Compounds, compositions and methods for the treatment of islet amyloid polypeptide (IAPP) accumulation in diabetes
Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of IAPP or amylin fibril diseases, and the manufacture of medicaments for such treatment. |
| US08563586B2 |
1,(3,)5-substituted imidazoles, their use in the treatment of hypertension and methods for their preparation
The present invention provides novel 1,5 and 1,3,5-substituted imidazole compounds in hydrophilic or lipophilic form, which are useful as angiotensin II ATI receptor antagonists suitable for transdermal delivery. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing compounds and their use in methods of treating hypertension and cardiovascular diseases. |
| US08563575B2 |
Fused heterocyclic compounds
The present invention provides a compound which has the effect of PDE inhibition, and which is useful as an agent for preventing or treating schizophrenia. The compound is represented by the formula (I): wherein the symbols are defined in the specification. |
| US08563567B2 |
Substituted heterocyclic compounds
The present invention relates to substituted heterocyclic compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted heterocyclic compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. |
| US08563566B2 |
Naphthyridine derivatives as potassium channel modulators
This invention provided compounds of formula I where W and Z are, independently, CH or N, and where other substituents are defined herein. Such compounds are potassium channel modulators. The invention also provides a composition comprising a pharmaceutically acceptable carrier or excipient and at least one of the following: a pharmaceutically effective amount of a compound of formula I; a pharmaceutically acceptable salt of a compound of formula I; a pharmaceutically acceptable ester of a compound of formula I. The invention also provides a method of preventing or treating a disease or disorder which is affected by activities of potassium channels, comprising administering to a patient in need thereof a therapeutically effective amount of a compound of formula I or a salt or ester or solvate thereof. |
| US08563561B2 |
3-(3-pyrimidine-2-yl-benzyl)-[1,2,4] triazolo[4,3-b]pyrimidine derivatives
The 3-(3-pyrimidin-2ylbenzyl)-1,2,4-triazolo[4,3-b]pyrimidine compounds of formula in which R1, R2, R3, R3, R4 have the meanings indicated herein, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors. |
| US08563558B2 |
Substituted pyridine urea compounds
The present disclosure provides pyridine urea compounds useful in the treatment of p38 kinase mediated diseases, such as lymphoma and auto-inflammatory disease, having the structure of Formula (I): wherein R1, R2, R3, R4, R5, V and W are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating p38 kinase mediated diseases using the compound. |
| US08563553B2 |
Compounds and compositions as protein kinase inhibitors
The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases. |
| US08563552B2 |
Whitening agent and skin external preparation
The present invention provides a compound having an excellent inhibitory action on melanin production and being useful as a whitening agent, and a skin external preparation containing the compound. The whitening agent of the present invention comprises, as an active ingredient, a compound represented by formula (1) or a pharmacologically acceptable salt thereof: wherein X1, X2, and X3 are each CR2 or N; R1, R2, and R3 are each H, C1-6 alkyl, C1-6 alkoxy, SH, OH, or NRbRc, wherein Rb and Rc are each H, C1-6 alkyl, or hydroxy-C1-6 alkyl, or NRbRc forms a saturated or unsaturated 5- or 6-membered hetero ring; and B is a substituted or unsubstituted pyrazole, imidazole, pyridine, or piperidine; with the proviso that at least one of R1, R3, R4, and R6 is a group other than C1-3 alkyl in the case where X1═X2═Y1═N and X3═CR2. |
| US08563550B2 |
Imidazolothiadiazoles for use as protein kinase inhibitors
There is provided compounds of formula (I), wherein Z, M, R1, X, R2, R3 and B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein kinase (e.g. a PIM family kinase or PI3-K) is desired and/or required, and particularly in the treatment of cancer. |
| US08563548B2 |
Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions
The present invention relates to methylene furanone derivatives as well as the use thereof as a protective, antioxidant, or depigmentation agent in cosmetic or dermatological compositions. The invention also relates to a method for preparing said derivatives involving a Suzuki-Miyaura coupling reaction from corresponding dibromofuranone derivatives. The invention also relates to a method of preparation involving a coupling reaction of 2-methoxy-furan derivatives with a ketone followed by dehydration. |
| US08563544B2 |
2,5-disubstituted arylsulfonamide CCR3 antagonists
Provided herein are 2,5-disubstituted arylsulfonamide CCR3 antagonists, e.g., compounds of Formula I, and pharmaceutical compositions thereof: Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a CCR3-mediated disorder, disease, or condition. |
| US08563539B2 |
Aminopyrimidine kinase inhibitors
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. |
| US08563536B2 |
Compounds having CRTH2 antagonist activity
Compounds of general formula (II) wherein W is chloro or fluoro; R1 is phenyl optionally substituted with one or more substituents, selected from halo, —CN, —C1-C6 alkyl, —SOR3, —SO2R3, —SO2N(R2)2, —N(R2)2, —NR2C(O)R3, —CO2R2, —CONR2R3, —NO2, —OR2, —SR2, —O(CH2)pOR2, or —O(CH2)pO(CH2)qOR2 wherein each R2 is independently hydrogen, —C1-C6 alkyl, —C3-C8 cycloalkyl, aryl or heteroaryl; each R3 is independently, —C1-C6 alkyl, —C3-C8 cycloalkyl, aryl or heteroaryl; p and q are each independently an integer from 1 to 3; and R4 is hydrogen, C1-C6 alkyl, C1-C6 alkyl substituted with aryl, aryl, (CH2)mOC(═O)C1-C6alkyl, ((CH2)mO)nCH2CH2X, (CH2)mN(R5)2 or CH((CH2)mO(C═O)R6)2; m is 1 or 2; n is 1-4; X is OR5 or N(R5)2; R5 is hydrogen or methyl; and R6 is C1-C18 alkyl; and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. |
| US08563535B2 |
Combination composition comprising benzoyl peroxide and adapalene
An aqueous gel composition of the present invention comprising about 0.1 to 0.3 wt % adapalene and about 2.5 to 5.0 wt % benzoyl peroxide, as active ingredients, wherein both the active ingredients are stabilized in hydrophilic gelling matrix of pH dependent gelling agent comprising crosslinked, acrylic acid-based polymer(s). |
| US08563533B2 |
Soft protease inhibitors and pro-soft forms thereof
The invention provides compounds and methods for inhibiting proteases. One aspect of the invention features pro-soft inhibitors which react with an activating protease to release an active inhibitor moiety in proximity to a target protease. In certain instances, compounds inhibit proteasomes and/or post-proline cleaving enzymes (PPCE), such as dipeptidyl peptidase IV. The compounds of the invention provide a better therapeutic index, owing in part to reduced toxicity and/or improved specificity for the targeted protease. |
| US08563531B2 |
Methods of using beta glucan as a radioprotective agent
The invention relates to methods for treating and preventing radiation and/or chemotherapy related injury and/or afflictions, such as myelosuppression and decreased macrophage activity, by administering a prophylactically or therapeutically effective amount of particulate, bioavailable β(1,3; 1,6) glucan. The invention also relates to methods in which β(1,3; 1,6) glucan is provided in the form of whole glucan particles, microparticulate β-glucan particles or a combination thereof. |
| US08563530B2 |
Purine nucleoside phosphoramidate
Disclosed herein is a compound represented by formula 1 or its hydrate thereof in crystalline or crystal-like form. |
| US08563528B2 |
Antisense oligomers targeting PCSK9
The present invention relates to oligomer compounds (oligomers), which target PCSK9 mRNA in a cell, leading to reduced expression of PCSK9. Reduction of PCSK9 expression is beneficial for the treatment of certain medical disorders, such as hypercholesterolemia and related disorders. |
| US08563526B2 |
Triazole derivatives, their preparation and their application in therapeutics
The present invention relates to novel compounds of formula (A): in the form of a free base or of an addition salt with an acid. The invention also relates to process of preparation of compounds of formula (A), to composition comprising them and to their application in therapeutics and in particular in cancers. |
| US08563525B2 |
Methods of treating an inflammatory-related disease
The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. The method typically comprises administration of one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, such as, Meisoindigo and NATURA in an amount less than sufficient to inhibit CDKs. |
| US08563523B2 |
Synthetic lipid A derivative
The invention provides functionalized monosaccharides and disaccharides suitable for use in synthesizing a lipid A derivative, as well as methods for synthesizing and using a synthetic lipid A derivative. |
| US08563521B2 |
Biological active proteins having increased in vivo and/or in vitro stability
Increased in vivo and/or in vitro stability is imparted to a biologically active protein by fusing to an amino acid sequence consisting of at least about 100 amino acid residues, which are Alanine, Serine and Proline, which form a random coil conformation. Specific examples are described. Also described are related nucleic acids, vectors and cells encoding such amino acids; compositions of biologically active proteins fused to a random coil domain, and methods of making and using the compounds and compositions of the invention. |
| US08563517B2 |
Dipeptidyl peptidase IV (DP-IV) compounds
The present invention is directed to novel compounds of formula I and pharmaceutically acceptable salts, enantiomers thereof having inhibiting properties of dipeptidyl peptidase IV enzyme (DP-IV inhibitors). The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds along with its composition in the prevention or treatment of diseases associated with DP-IV enzyme. wherein, A is defined as R3-R4 wherein R3 and R4 are together or independently defined as peptides having amino acids ranging from 1 to 10, B is chemical bond between peptide and substituted amine, R1, and R2 are as defined in specification. |
| US08563516B2 |
Foxp3 peptide vaccine
The present invention provides Foxp3 peptides comprising the amino acid sequence of SEQ ID NOs: 3-5, 7-9, 12, 15-19, 22, 24, 27-30, 37, 67 or 74, and Foxp3 peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or added, and having cytotoxic T cell inducibility, and also provides drugs for regulating regulatory T cells comprising these Foxp3 peptides. The Foxp3 peptides of this invention find use as vaccines. |
| US08563514B2 |
Peptides and pharmaceutical compositions for treating connective tissue
Provided is a pharmaceutical composition for sequestering cells in connective tissue. The composition includes a biocompatible scaffolding to which one or more peptides or proteins are linked. The peptides or proteins have an amino acid sequence that is a subsequence of human ficolin and are capable of binding the cells to be sequestered. The pharmaceutical composition can be used in the treatment of connective tissue, and can be used as a dermal filler. |
| US08563511B2 |
Treatment of pulmonary hypertension using an agent that inhibits a tissue factor pathway
An improved non-human animal model of severe pulmonary arterial hypertension (PAH) and its use for testing of therapeutic agents that can treat symptoms of PAH are disclosed. In addition, the present application relates to the identification of several classes of therapeutic agents that, alone or in combination, can be used to treat or prevent PAH or at least reduce the severity of symptoms associated therewith. Both gene therapy and non-gene therapy approaches are described. |
| US08563510B2 |
Free-standing biodegradable patch
Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents. |
| US08563509B2 |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates and methods of making said conjugates
The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a non-cleavable linker and the cell-binding agent binds to cells of the selected cell population. |
| US08563503B2 |
Antibiotic, its nucleotide sequence, methods of construction and uses thereof
The present invention belongs to field of biology and medicine, and especially relates to a novel antibiotic, its nucleotide sequence, methods of construction and uses thereof. A novel antibiotic, wherein the end of any peptide of the allosteric colicin is connected linearly to the end of peptide of the Staphylococcus aureus pheromone AgrD I, AgrD II, AgrD III, AgrD IV or Staphylococcus epidermidis pheromone. Wherein the allosteric colicin being yielded by artificially mutating the amino acid residues G11A, H22R, A26G, V31L and H40K in the peptide chain of wild type Colicin E1, Ia, Ib, A, B, N, or their ion channel-forming structural domain. In comparison with the traditional antibiotics, the novel antibiotics in the present invention are not likely to lead to drug resistance and cause hypersensitivity reaction. |
| US08563494B2 |
Iridescent soap bars containing ethoxylated alcohols
An iridescent continuous phase soap bar with an ordered layered microstructure containing soap, water and specific ethoxylated alcohols is described. The phenomena of continuous phase iridescence in a soap bar is characterized as blue hue which intensity depends on the viewing angle and on the background color used for its observation by the user. In a preferred embodiment, the iridescent soap bar is prepared with mixing equipment capable of creating intensive mass shearing conditions and which generate high compression and extensional forces on the processed soap mass. |
| US08563492B2 |
Skin cleansing agent with particles containing hydrogenated castor oil
A skin cleaning agent containing from 2 to 25% by weight of a cleaning body having a mean grain size of from 100 to 1000 μm and containing at least 50% hydrogenated castor oil; from 2 to 30% by weight of surfactants; from 0.1 to 10% by weight of thickeners; water and optionally further auxiliaries. |
| US08563487B1 |
Friction modifier using adherent metallic multilayered or mixed element layer conversion coatings
A process for creating conversion coatings and spin, drawing, and extrusion finishes for surfaces, wherein the conversion coatings and spin, drawing, and extrusion finishes contain potassium, phosphorus, nitrogen, and one or more non-alkaline metals and/or one or more metalloids. The process comprises forming an aqueous solution of water, phosphoric acid or sulfuric acid, ammonium hydroxide, an alkali metal hydroxide, and one or more non-alkaline metals and/or one or more metalloids. The aqueous solution forms an anti-friction multilayer conversion and/or mixed element coating or a spin, drawing, and extrusion finish on a surface when applied to the surface, either directly without the use of applied external electromotive force, or as an additive in lubricating fluids. |
| US08563476B2 |
Anti-CXCL9, anti-CXCL10, anti-CXCL11, anti-CXCL13, anti-CXCR3 and anti-CXCR5 agents for inflammatory disorders
A method for detecting an inflammatory disease in a subject is disclosed. The method comprises the steps of (a) detecting a level of expression of one or more inflammatory disease markers in a biological sample obtained from the subject; and (b) comparing the level of expression of said one or more inflammatory disease markers in the biological sample to a normal level of expression of the one or more inflammatory disease markers, wherein the one or more inflammatory disease markers comprise one or more markers selected from the group consisting of CXCL9, CXCL10, CXCL11, CXCL13, CXCR3 and CXCR5. Also disclosed are a method for monitoring the course of treatment for an inflammatory disease in a subject and a kit for detecting an inflammatory disease in a subject. |
| US08563473B2 |
Aqueous herbicidal concentrates of auxinic carboxylic acids with reduced eye irritancy
Aqueous concentrates of choline salts of herbicidal auxinic carboxylic acids are less irritating to eyes than the commonly used aqueous concentrates of ammonium salts of herbicidal auxinic carboxylic acids. |
| US08563469B2 |
Acrylate/methacrylate-based random copolymer/anthranilic diamide compositions for propagule coating
Disclosed is an insecticidal composition comprising by weight based on the total weight of the composition: (a) from about 9 to about 91% of one or more anthranilic diamide insecticides; and (b) from about 9 to about 91% of an acrylate/methacrylate-based random copolymer component having a water solubility of at least about 5% by weight at 20° C., a hydrophilic-lipophilic balance value of at least about 3, and an average molecular weight ranging from about 1,500 to about 50,000 daltons; wherein the ratio of component (b) to component (a) is about 1:10 to about 10:1 by weight. Also disclosed is a geotropic propagule coated with the insecticidal composition.Further disclosed is a liquid composition comprising the insecticidal composition, and a method for protecting a geotropic propagule and plant derived therefrom from a phytophagous insect pest. |
| US08563468B2 |
Color developing composition containing molecular compound, and recording material
Provided is a color-developing composition containing a molecular compound which has as a component compound a compound represented by formula (I) [wherein Y represents a C1-C12 hydrocarbon group which is chained or branched and saturated or unsaturated, or a C1-C8 hydrocarbon group which is chained or branched, saturated or unsaturated and has an ether or thioether bond; R1, R2, R3 and R4 each independently represent a C1-C6 alkyl group or C2-C6 alkenyl group; n, p, q and r each represents any integer of 0 to 4; and m represents any integer of 0 to 2]. Also provided is a recording material with a sufficient color-forming sensitivity, superior storage stability, and especially with an extremely little background fogging in a heat resistance test. |
| US08563467B2 |
Method for preparation of activated carbon
A method of preparing activated carbon, is disclosed, comprising: exposing carbonaceous material to microwave radiation in the presence of water to produce activated carbon. |
| US08563466B2 |
Polysaccharide-inorganic composite particles as performance additives for super-absorbent polymers
The present invention relates to discrete particulate composite additives for superabsorbent polymers and includes a method of making same. The discrete particulate composite additives generally comprise a polysaccharide and an inert inorganic component. Advantageously, these discrete particulate composite additives functionally improve superabsorbent performance. They are suitable for a number of applications, including the use and manufacture of hygiene products. |
| US08563465B2 |
Hydrogen storage material
The hydrogen storage material of the invention is a hydrogen storage material comprising metal fine particles with hydrogen storage capacity, and an organic compound that has at least two specific groups that can bind with the metal fine particles, and that is bonded with the metal fine particles by the specific groups. |
| US08563462B2 |
Catalyst compositions based on nanoparticles of a zirconium oxide, a titanium oxide or a mixed zirconium/titanium oxide deposited onto a silica support therefor
Catalyst compositions include finely divided nanoscale particles of at least one supported oxide, based on a zirconium oxide, a titanium oxide or a mixed zirconium/titanium oxide deposited onto a silica based support, wherein, after calcination for 4 hours at 900° C., the supported oxide is in the form of nanoscale particles deposited onto the support, the size of the particles being at most 5 nm when the at least one supported oxide is based on a zirconium oxide, being at most 10 nm when the at least one supported oxide is based on a titanium oxide and being at most 8 nm when the at least one supported oxide is based on a mixed zirconium/titanium oxide; such catalyst compositions are especially useful for the selective reduction of NOx. |
| US08563456B2 |
Hydrodemetallization catalyst and process
This invention is directed to hydrodemetallization catalysts and hydrodemetallization processes employing a magnesium aluminosilicate clay. The magnesium aluminosilicate clay has a characteristic 29Si NMR spectrum. The magnesium aluminosilicate clay is the product of a series of specific reaction steps. Briefly, the magnesium aluminosilicate clay employed in the catalyst and process of the invention is made by combining a silicon component, an aluminum component, and a magnesium component, under aqueous conditions and at an acidic pH, to form a first reaction mixture and subsequently the pH of the first reaction mixture is adjusted to greater than about 7.5 to form a second reaction mixture. The second reaction mixture is allowed to react under conditions sufficient to form the magnesium aluminosilicate clay. The resulting magnesium aluminosilicate clay combines high surface area and activity for use in hydrodemetallization catalysts and processes. |
| US08563455B2 |
Process for regenerating catalyst
Disclosed is a catalyst distributor and process for mixing spent catalyst and recycled regenerated catalyst in a regenerator vessel. Mixing is conducted in a confined space to which catalyst is delivered from catalyst conduits protruding through the wall of the regenerator. |
| US08563454B2 |
Refractory product with high zirconia content
A fused and cast refractory product including, in mass percentages on the basis of the oxides and for a total of 100% of the oxides: ZrO2 + Hf2O:balance to 100%; SiO2: 7.0% to 11.0%; Al2O3:0.2% to 0.7%; Na2O + K2O:<0.10%; B2O3:0.3% to 1.5%; CaO + SrO + MgO + ZnO + BaO: <0.4%; P2O5:<0.15%; Fe2O3 + TiO2:<0.55%; Other oxide species: <1.5%; the mass content of a dopant selected from Nb2O5, Ta2O5 and mixtures thereof being of less or equal to 1.0%, and the A/B ratio of the Al2O3/B2O3 mass contents being less than or equal to 2.0. |
| US08563448B2 |
Friction member and friction material thereof
A friction material includes a resin and a fibrous base material impregnated with the resin. The fibrous base material has a single ply, and includes a plurality of aramid fibers present in a first amount, a plurality of polyacrylonitrile-based carbon fibers present in a second amount that is less than the first amount, a plurality of carbon particles present in a third amount that is less than or equal to the second amount, a plurality of mineral fibers present in a fourth amount that is less than or equal to the second amount, and diatomaceous earth present in a fifth amount that is greater than the first amount. A friction member for operatively contacting a lubricated surface includes a substrate and the friction material. The friction material defines a first surface bonded to the substrate and a second surface configured for operatively contacting the lubricated surface. |
| US08563446B2 |
Technique to create a buried plate in embedded dynamic random access memory device
A method for forming a trench structure is provided for a semiconductor and/or memory device, such as an DRAM device. In one embodiment, the method for forming a trench structure includes forming a trench in a semiconductor substrate, and exposing the sidewalls of the trench to an arsenic-containing gas to adsorb an arsenic containing layer on the sidewalls of the trench. A material layer is then deposited on the sidewalls of the trench to encapsulate the arsenic-containing layer between the material layer and sidewalls of the trench. |
| US08563441B2 |
Methods for fabricating memory cells having fin structures with smooth sidewalls and rounded top corners and edges
Methods for fabricating a semiconductor FIN structure with smooth sidewalls and rounded top corners and edges is disclosed. A method includes forming a plurality of semiconductor FIN structures. A sacrificial oxide layer is formed on the top surface and the sidewall surfaces of the plurality of semiconductor FIN structures for rounding the corners and edges between the top surfaces and the sidewall surfaces of the plurality of semiconductor FIN structures. The sacrificial oxide layer is removed with a high selectivity oxide etchant. The plurality of semiconductor FIN structures are annealed in a hydrogen environment. A tunnel oxide is formed over the plurality of semiconductor FIN structures. |
| US08563439B2 |
Method of pitch dimension shrinkage
An embodiment of the disclosure includes a method of pitch reduction. A substrate is provided. A first material layer is formed over the substrate. A second material layer is formed on the first material layer. A hardmask layer is formed on the second material layer. A first imaging layer is formed on the hardmask layer. The first imaging layer is patterned to form a plurality of first features over the hardmask layer. The hardmask layer is etched utilizing the first imaging layer as a mask to form the first features in the hardmask layer. The first imaging layer is removed to expose the etched hardmask layer and a portion of a top surface of the second material layer. A second imaging layer is formed and the process is repeated, such that first and second features are alternating with a pitch substantially half the original pitch. |
| US08563434B2 |
Semiconductor device contacts
A method of fabrication of electrical contact structures on a semiconductor material includes depositing an oxide of a desired contact material by a chemical electroless process on a face of the semiconductor material and reducing the oxide via a chemical electroless process to produce a contact of the desired contact material. A method of fabrication of a semiconductor device incorporating such electrical contact structures and a semiconductor device incorporating such electrical contact structures are also described. |
| US08563430B2 |
Semiconductor integrated circuit and method for fabricating the same
A semiconductor integrated circuit includes: a semiconductor chip; a through-chip via passing through a conductive pattern disposed in the semiconductor chip and cutting the conductive pattern; and an insulation pattern disposed on an outer circumference surface of the through-chip via to insulate the conductive pattern from the through-chip via. |
| US08563425B2 |
Selective local interconnect to gate in a self aligned local interconnect process
A semiconductor device fabrication process includes forming a gate of a transistor on a semiconductor substrate using a hard mask. The hard mask is selectively removed in one or more selected regions over the gate. The removal of the hard mask in the selected regions allows the gate to be connected to an upper metal layer through at least one insulating layer located substantially over the transistor. Conductive material is deposited in one or more trenches formed through the at least one insulating layer. The conductive material forms a local interconnect to the gate in at least one of the selected regions. |
| US08563418B2 |
Semiconductor device and method of forming vertically offset bond on trace interconnects on different height traces
A method of making a semiconductor device includes providing a substrate, and forming a first conductive layer over the substrate. A patterned layer is formed over the first conductive layer. A second conductive layer is formed in the patterned layer. A height of the second conductive layer is greater than a height of the first conductive layer. The patterned layer is removed. A first bump and a second bump are formed over the first and second conductive layers, respectively, wherein the second bump overlaps the first bump, and wherein an uppermost surface of the second bump is vertically offset from an uppermost surface of the first bump. Bond wires are formed on the first and second bumps. The bond wires are arranged in a straight configuration. Lowermost surfaces of the first conductive layer and second conductive layer are substantially coplanar. |
| US08563412B2 |
Method of fabricating semiconductor device
A method of fabricating a semiconductor device includes forming gate patterns on a substrate, forming spacers on sidewalls of the gate patterns, forming a first capping insulation layer pattern on the gate patterns and the spacers, forming a second capping insulation layer pattern on the first capping insulation layer pattern, forming a passivation layer pattern filling contact holes between the gate patterns, removing the second capping insulation layer pattern while protecting the spacers using the passivation layer pattern, removing the passivation layer pattern to expose a top surface of the substrate, forming a silicide forming metal film on the surface of the substrate, and forming silicide patterns on the exposed top surface of the substrate. |
| US08563410B2 |
End-cut first approach for critical dimension control
A method for fabricating a semiconductor device is disclosed. The method includes forming at least one material layer over a substrate; performing an end-cut patterning process to form an end-cut pattern overlying the at least one material layer; transferring the end-cut pattern to the at least one material layer; performing a line-cut patterning process after the end-cut patterning process to form a line-cut pattern overlying the at least one material layer; and transferring the line-cut pattern to the at least one material layer. |
| US08563407B2 |
Dual sided workpiece handling
A method includes positioning at least one dual sided workpiece on an assembly in a process chamber to expose a first side of the at least one dual sided workpiece, treating the first side of the at least one dual sided workpiece, reorienting a portion of the assembly in the process chamber to expose a second side of the at least one dual sided workpiece, the second side opposing the first side, and treating the second side. A processing apparatus including a process chamber defining an enclosed volume and a dual sided workpiece assembly disposed in the enclosed volume is also provided. |
| US08563405B2 |
Method for manufacturing semiconductor device
A method for manufacturing semiconductor device includes the following steps. First, a carrier substrate and a plurality of pieced segments of wafer are provided. Each of the pieced segments of wafer has an active surface and a back surface on opposite sides thereof. Further, there is at least a bonding pad disposed on the active surface. Next, an adhering layer is formed between the carrier substrate and the active surfaces of the pieced segments of wafer, so as to make the pieced segments of wafer adhere to the carrier substrate. Next, a through silicon via is formed in each of the pieced segments of wafer to electrically connect to the bonding pad correspondingly. Then, the pieced segments of wafer are separated from the carrier substrate. |
| US08563401B2 |
Method for fabricating SOI substrate
There is provided a method for manufacturing an SOI substrate capable of effectively and efficiently embrittling an interface of an ion-implanted layer without causing the separation of a bonded surface 9 or the breakage of a bonded wafer.Provided is a method for manufacturing an SOI substrate 8 by forming an SOI layer 4 on a surface of a transparent insulating substrate 3, the method comprising, in the following order, implanting ions into a silicon wafer 5 or a silicon wafer 5 with an oxide film 7 from a surface thereof so as to form an ion-implanted layer 2; subjecting at least one of the surface of the transparent insulating substrate and the surface of the ion-implanted silicon wafer or the silicon wafer with an oxide film to a surface activation treatment; bonding together the silicon wafer 5 or the silicon wafer 5 with an oxide film 7 and the transparent insulating substrate 3; subjecting the bonded wafer to a heat treatment at 150° C. or higher but not higher than 350° C. so as to obtain a laminate 6; and irradiating visible light at a side of the transparent insulating substrate 3 of the laminate 6 toward the ion-implanted layer 2 of the silicon wafer 5 or the silicon wafer 5 with an oxide film 7 to embrittle an interface of the ion-implanted layer 2 and transfer a silicon thin film to the transparent insulating substrate 3 so that the SOI layer 4 can be formed. |
| US08563391B2 |
Method for forming MIM capacitor in a copper damascene interconnect
A method for forming a metal-insulator-metal capacitor in a multilevel semiconductor device utilizes the copper interconnect levels of the semiconductor device as parts of the capacitor. A lower capacitor plate consists of a copper interconnect level and a first metal layer formed on the copper interconnect level by selective deposition methods. The upper capacitor plate includes the same pattern as the capacitor dielectric, the pattern having an area less than the area of the lower capacitor plate. The upper capacitor plate is formed of a second metal layer. The first and second metal layers may each be formed of cobalt, tungsten, nickel, molybdenum, or a combinations of one of the aforementioned elements with boron and/or phosphorus. Conductive vias provide contact from the upper capacitor plate and lower capacitor plate, to interconnect levels. |
| US08563388B2 |
Method for producing a plurality of integrated semiconductor components
A method for producing a plurality of integrated semiconductor components on a carrier, in which an active basic structure is introduced into the carrier in a continuous fashion at least across a portion of the boundaries of the semiconductor components to be created. The regions of the semiconductor components on the carrier are defined, and a covering layer is applied to the carrier in the region of each semiconductor component with the aid of a mask. The carrier is severed to form the individual semiconductor components at the boundaries thereof. |
| US08563386B2 |
Integrated circuit system with bandgap material and method of manufacture thereof
A method of manufacturing an integrated circuit system includes: providing a substrate having a channel region; forming a gate stack over a portion of the channel region with the gate stack having a floating gate for storing an electrical charge; forming a source recess in the substrate adjacent to the gate stack; and forming a source by layering a first bandgap material in the source recess. |
| US08563385B2 |
Field effect transistor device with raised active regions
A method for fabricating a field effect transistor device includes forming a gate stack on a substrate, forming a spacer on the substrate, adjacent to the gate stack, forming a first portion of an active region on the substrate, the first portion of the active region having a first facet surface adjacent to the gate stack, forming a second portion of the active region on a portion of the first portion of the active region, the second portion of the active region having a second facet surface adjacent to the gate stack, the first facet surface and the second facet surface partially defining a cavity adjacent to the gate stack. |
| US08563384B2 |
Source/drain extension control for advanced transistors
A planar transistor with improved performance has a source and a drain on a semiconductor substrate that includes a substantially undoped channel extending between the source and the drain. A gate is positioned over the substantially undoped channel on the substrate. Implanted source/drain extensions contact the source and the drain, with the implanted source/drain extensions having a dopant concentration of less than about 1×1019 atoms/cm3′, or alternatively, less than one-quarter the dopant concentration of the source and the drain. |
| US08563383B2 |
Method of manufacturing a semiconductor device
A method of manufacturing a semiconductor device includes forming a plurality of gate structures including a metal on a substrate having an isolation layer, forming first insulating interlayer patterns covering sidewalls of the gate structures, forming first capping layer patterns and a second capping layer pattern on the gate structures and the first insulating interlayer patterns, the first capping layer patterns covering upper faces of the gate structures, and the second capping layer pattern overlapping the isolation layer, partially removing the first insulating interlayer patterns using the first and the second capping layer patterns as etching masks to form first openings that expose portions of the substrate, forming metal silicide patterns on the portions of the substrate exposed in the forming of the first openings, and forming conductive structures on the metal silicide patterns. |
| US08563382B2 |
Semiconductor device
A semiconductor device includes, a gate insulating film, a gate electrode, a source/drain region, and a Si mixed crystal layer in the source/drain region. The Si mixed crystal layer includes a first Si mixed crystal layer that includes impurities with a first concentration, a second Si mixed crystal layer formed over the first Si mixed crystal layer and that includes the impurities with a second concentration higher than the first concentration, and a third Si mixed crystal layer formed over the second Si mixed crystal layer and that includes the impurities with a third concentration lower than the second concentration. |
| US08563381B2 |
Method for manufacturing a power semiconductor device
A power semiconductor device with improved avalanche capability structures is disclosed. By forming at least an avalanche capability enhancement doped regions with opposite conductivity type to epitaxial layer underneath an ohmic contact doped region which surrounds at least bottom of trenched contact filled with metal plug between two adjacent gate trenches, avalanche current is enhanced with the disclosed structures. |
| US08563379B2 |
Semiconductor device and production method thereof
A method for producing a semiconductor device includes preparing a structure having a substrate, a planar semiconductor layer and a columnar semiconductor layer, forming a second drain/source region in the upper part of the columnar semiconductor layer, forming a contact stopper film and a contact interlayer film, and forming a contact layer on the second drain/source region. The step for forming the contact layer includes forming a pattern and etching the contact interlayer film to the contact stopper film using the pattern to form a contact hole for the contact layer and removing the contact stopper film remaining at the bottom of the contact hole by etching. The projection of the bottom surface of the contact hole onto the substrate is within the circumference of the projected profile of the contact stopper film formed on the top and side surface of the columnar semiconductor layer onto the substrate. |
| US08563378B2 |
Manufacturing semiconductor devices
A semiconductor device includes a semiconductor pattern on a substrate, gate structures on sidewalls of the semiconductor pattern, the gate structures being spaced apart from one another, insulating interlayers among the gate structures, wherein an uppermost insulating interlayer is lower than an upper face of the semiconductor pattern, a common source line contacting the substrate and protruding above the uppermost insulating interlayer, an etch stop layer pattern on the semiconductor pattern and on the common source line wherein the common source line protrudes above the uppermost insulating interlayer, an additional insulating interlayer on the uppermost insulating interlayer, and contact plugs extending through the additional insulating interlayer so as to make contact with the semiconductor pattern and the common source line, respectively. |
| US08563366B2 |
Memory device having an integrated two-terminal current limiting resistor
A resistor structure incorporated into a resistive switching memory cell or device to form memory devices with improved device performance and lifetime is provided. The resistor structure may be a two-terminal structure designed to reduce the maximum current flowing through a memory device. A method is also provided for making such memory device. The method includes depositing a resistor structure and depositing a variable resistance layer of a resistive switching memory cell of the memory device, where the resistor structure is disposed in series with the variable resistance layer to limit the switching current of the memory device. The incorporation of the resistor structure is very useful in obtaining desirable levels of device switching currents that meet the switching specification of various types of memory devices. The memory devices may be formed as part of a high-capacity nonvolatile memory integrated circuit, which can be used in various electronic devices. |
| US08563354B1 |
Advanced 2-step, solid source deposition approach to the manufacture of CIGS solar modules
A novel 2 step solid source deposition (2SSS) method to form an absorber layer in the manufacture for CIGS solar modules. 2-step refers to a first step of deposition of metals followed by second step of selenization of the metal stack. Metals are first deposited and then selenized in an adjacent chamber. Differential pumping is used to control egress of Se vapor into the sputtering region and prevent contamination of the targets. Products made by the method demonstrate comparable quality and performance to those produced by current processing techniques. The 2SSS method provides means for attaining improved uniformity of large area films which improves yield and cost-effectiveness. |
| US08563351B2 |
Method for manufacturing photovoltaic device
A photovoltaic device manufacturing method is disclosed. Methods include manufacturing a photovoltaic cell using nanoimprint technology to define individual cell units of the photovoltaic device. The methods can include providing a substrate; forming a first conductive layer over the substrate; forming first grooves in the first conductive layer using a nanoimprint and etching process; forming an absorption layer over the first conductive layer, the absorption layer filling in the first grooves; forming second grooves in the absorption layer using a nanoimprint process; forming a second conductive layer over the absorption layer, the second conductive layer filling in the second grooves; and forming third grooves in the second conductive layer and the absorption layer, thereby defining a photovoltaic cell unit. |
| US08563350B2 |
Wafer level image sensor packaging structure and manufacturing method for the same
The present invention discloses a wafer level image sensor packaging structure and a manufacturing method for the same. The manufacturing method includes the following steps: providing a silicon wafer with image sensor chips, providing a plurality of transparent lids, allotting one said transparent lid on top of the corresponding image sensor chip, and carrying out a packaging process. The manufacturing method of the invention has the advantage of having a simpler process, lower cost, and higher production yield rate. The encapsulation compound arranges on the first surface of the image sensor chip and covers the circumference of the transparent lid to avoid the side light leakage as traditional chip scale package (CSP). Thus, the sensing performance of the wafer level image sensor packaging structure can be enhanced. |
| US08563344B2 |
Method for producing MEMS structures, and MEMS structure
A method for producing microelectromechanical structures in a substrate includes: arranging at least one metal-plated layer on a main surface of the substrate in a structure pattern; leaving substrate webs open beneath a structure pattern region by introducing first trenches into the substrate perpendicular to a surface normal of the main surface in a region surrounding the structure pattern; coating the walls of the first trenches perpendicular to the surface normal of the main surface with a passivation layer; and introducing cavity structures into the substrate at the base of the first trenches in a region beneath the structure pattern region. |
| US08563343B2 |
Method of manufacturing laser diode device
A method of manufacturing a laser diode device includes: forming, in a semiconductor laser bar, separation trenches extending across all of a transverse dimension of the semiconductor laser bar and defining a mesa stripe, each of the separation trenches having wide portions located at longitudinal edge portions of the semiconductor laser bar and a narrow portion located in a longitudinal central portion of the semiconductor laser bar; scribing, in the semiconductor laser bar, grooves extending parallel to the separation trenches and terminating before reaching longitudinal edge portions of the semiconductor laser bar; and splitting the semiconductor laser bar along the grooves to form cleaved surfaces extending from a bottom surface of the semiconductor laser bar to bottom surfaces of the separation trenches. |
| US08563334B2 |
Method to remove sapphire substrate
A Light-Emitting Diode (LED) is formed on a sapphire substrate that is removed from the LED by grinding and then etching the sapphire substrate. The sapphire substrate is ground first to a first specified thickness using a single abrasive or multiple abrasives. The remaining sapphire substrate is removed by dry etching or wet etching. |
| US08563332B2 |
Wafer reclamation method and wafer reclamation apparatus
Provided is a wafer reclamation method for reclaiming a semiconductor wafer, on which a different material layer is formed, by removing the different material layer. The wafer reclamation method includes a physically removing step of physically removing the different material layer, a film forming step of forming a film on a surface of the semiconductor wafer from which the different material layer has been removed in the physically removing step, and a dry etching step of etching the semiconductor wafer by plasma together with the film formed in the film forming step. |
| US08563329B2 |
Polymer conjugate enhanced bioassays
Modified branched polymers are combined with bioactive agents which are one member of a binding pair for use in an assay. |
| US08563325B1 |
Coaxial microreactor for particle synthesis
A coaxial fluid flow microreactor system disposed on a microfluidic chip utilizing laminar flow for synthesizing particles from solution. Flow geometries produced by the mixing system make use of hydrodynamic focusing to confine a core flow to a small axially-symmetric, centrally positioned and spatially well-defined portion of a flow channel cross-section to provide highly uniform diffusional mixing between a reactant core and sheath flow streams. The microreactor is fabricated in such a way that a substantially planar two-dimensional arrangement of microfluidic channels will produce a three-dimensional core/sheath flow geometry. The microreactor system can comprise one or more coaxial mixing stages that can be arranged singly, in series, in parallel or nested concentrically in parallel. |
| US08563323B2 |
Using plasma proteomic pattern for diagnosis, classification, prediction of response to therapy and clinical behavior, stratification of therapy, and monitoring disease in hematologic malignancies
The present invention demonstrates that the diagnosis and prediction of clinical behavior in patients with hematologic malignancies, such as leukemia, can be accomplished by analysis of proteins present in a plasma sample. Thus, in particular embodiments the present invention uses plasma to create a diagnostic or prognostic protein profile of a hematologic malignancy comprising collecting plasma samples from a population of patients with hematologic malignancies; generating protein spectra from the plasma samples with or without fractionation; comparing the protein spectra with clinical data; and identifying protein markers in the plasma samples that correlate with the clinical data. Protein markers identified by this approach can then be used to create a protein profile that can be used to diagnose the hematologic malignancy or determine the prognosis of the hematologic malignancy. Potentially these specific proteins can be identified and targeted in the therapy of these malignancies. |
| US08563322B2 |
Method for separation of molecules
A method for separating molecules, such as enantiomers, other stereoisomers and constitutional isomers by ion mobility spectrometry (IMS). Molecules of interest are ionised after addition of a suitable chiral reference compound, resulting in the formation of cluster ions that can be separated by IMS techniques such as ion drift mobility (IDM) spectrometry or FAIMS. This method allows, for example, for fast and sensitive quantification of one enantiomer in presence of an excess of the other enantiomer. |
| US08563319B2 |
Differential resonators for NO2 detection and methods related thereto
A nitrogen dioxide sensor comprising a first beam having a first functionalized sensing surface capable of sensing nitrogen dioxide, the first beam capable of producing a first resonant frequency; and a second beam having a second functionalized reference surface not capable of sensing nitrogen dioxide, the second beam capable of producing a second resonant frequency, wherein differential sensing of nitrogen dioxide may be performed, further wherein the first beam and the second beam are each functionalized with one or more soft bases having comparable viscoelastic properties is provided. In one embodiment, the sensor is a nano-sensor capable of low drift and accurate detection of nitrogen dioxide levels at the zeptogram level. Methods of making and using a nitrogen dioxide sensor are also provided. |
| US08563318B2 |
Method for the diagnosis of non-alcoholic steatohepatitis based on a metabolomic profile
The invention relates to methods for the diagnosis of non-alcoholic steatosis (NASH). The method relies on the determination of certain metabolic markers in a biological sample of the patient which are up- or down-regulated in the NASH patients vs. patients with a simple fatty liver (steatosis). |
| US08563315B2 |
Calibration substances for atmospheric pressure ion sources
A Mixture of substances is provided for precise calibration of the mass scale of mass spectrometers equipped with ion sources that operate at atmospheric pressure (AP) with ionization of the analyte molecules, for example by APCI (chemical ionization), or by APPI (photoionization), often at high temperatures of up to 470° C. Out of physical reasons, the mass scale of any time-of-flight mass spectrometer deviates in the lower mass range from the theoretical relation between charge-related mass m/z and flight time t. A closely spaced arrangement of low mass calibration reference points is necessary if high mass accuracy is to be achieved for substances of low molecular weight. APCI and APPI sources are increasingly used in time-of-flight mass spectrometers with orthogonal ion injection (OTOF MS) for the detection of non-polar and weakly polar compounds, in particular, for analyte molecules with relatively low molecular weights. Calibration substances in solutions that are easily handled, nontoxic, stable at the high temperatures involved, will accept both positive and negative ionization, and supply enough reference points for calibration in the mass range up to 500 daltons. Mixtures of saturated fatty acids dissolved in toluene may be used. For photoionization, also mixtures of phenyl and naphthyl fatty acids. |
| US08563314B2 |
Methods and compositions for modulating PD1
Disclosed herein are methods and compositions for modulating expression of a PD1 gene. |
| US08563313B2 |
Macrophage cell-lines for propagation of porcine reproductive and respiratory syndrome virus
Particular aspects provide novel recombinant cells and cell lines (e.g., macrophage cell lines) that are permissive for propagation of porcine reproductive and respiratory syndrome virus (PRRSV) propagation in vitro or in vivo. In certain aspects, novel nucleic acid sequences encoding porcine sialoadhesin were transfected into existing macrophage cell-lines from other species, rendering them permissive to PRRSV infection, and suitable for propagation of PRRSV. Particular aspects provide exemplary recombinant cloned cell lines that support the replication of PRRSV, with an obtainable PRRSV titre of between 2×105/ml and 2×106/ml. Additional aspects provide novel nucleic acid sequences and polymorphisms thereof that encode for porcine sialoadhesin. Further aspects provide PRRSV propagation and preparation methods using the novel recombinant cell lines, and methods for PRRSV antigen and vaccine production using same. Yet further aspect provide transgenic, chimerical or engrafted animals having cell comprising nucleic acid sequences encoding porcine sialoadhesin. |
| US08563312B2 |
Synthetic surfaces for culturing stem cell derived cardiomyocytes
Synthetic surfaces suitable for culturing stem cell derived cardiomyocytes contain acrylate polymers formed from one or more acrylate monomers. The acrylate surfaces, in many cases, are suitable for culturing stem cell derived cardiomyocytes in chemically defined media. |
| US08563308B2 |
Culture-expanded T suppressor cells and methods of use thereof
This invention relates to culture-expanded T suppressor cells derived from CD25−CD4+ T cells, and their use in modulating immune responses. This invention provides methods of producing culture-expanded T suppressor cells, which are antigen specific, and their use in modulating autoimmune diseases and transplantation rejection. |
| US08563302B2 |
Optimized high yield synthetic plasmids
One aspect of the current invention is an optimized synthetic mammalian expression plasmid with a mutated origin of replication (e.g. “mut” family of plasmids) comprising a therapeutic element, and a replication element. The therapeutic elements of this plasmid are operatively linked and located in a first operatively-linked arrangement. Additionally, the optimized synthetic mammalian expression plasmid comprises replication elements, wherein the replication elements are operatively linked and located in a second operatively-linked arrangement. The first-operatively-linked arrangement and the second-operatively-linked arrangement comprise a circular structure of the codon optimized synthetic mammalian expression plasmid. |
| US08563300B2 |
Incubator
An incubator comprising: a culture chamber configured to accommodate culture; a dish structure configured to contain a liquid; an ultrasonic vibrator provided in a part of the dish structure, the ultrasonic vibrator configured to atomize the liquid; and a gas-liquid contact structure configured to bring the atomized liquid into contact with air in the chamber to be cultured. |
| US08563299B2 |
Moving bed biofilm reactor (MBBR) process for conversion of syngas components to liquid products
A process for converting a feed gas containing at least one of CO, CO2, and/or H2 to a liquid product using biomass that grow on the surface of carriers suspended in a fermentation broth within the vessel of a moving bed bioreactor (MMBR). An injector is used to at least partially dissolved the feed gas in the fermentation broth, at least partially entrain the gas in the broth as microbubbles and to introduce the mixture of the entrained gas and broth into the vessel in a substantially horizontal direction. The injection of the mixture creates eddy current in the surrounding liquid for thoroughly mixing the fermentation broth in the vessel and for keeping the biomass carrier moving to provide sufficient shear so as to maintain a biofilm thickness on the carrier in a desirable range. |
| US08563293B2 |
Bacteriocin based methods to control lactic acid bacterial growth
The present invention relates to compositions and methods for protection against bacterial contamination. The invention provides bactericidal yeast expressing bacteriocin proteins and methods of using the bactericidal yeast. |
| US08563285B2 |
Isoforms of eIF-5A: senescence-induced eIF5A; wounding-induced eIF-5A; growth eIF-5A; and DHS
The present invention relates to unique isoforms of eukaryotic initiation Factor 5A (“eIF-5A”): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase (“DHS”), polynucleotides that encode DHS, and methods involving modulating the expression of DHS. |
| US08563284B2 |
Thermostable Paenibacillus xylanases
This invention relates to mutant xylanases, nucleic acids encoding them, and methods of using these xylanases. |
| US08563278B2 |
Process of producing glutamate derivatives
A process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin is described. This process entails converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same. |
| US08563277B1 |
Methods and systems for saccharification of biomass
Provided are methods and compositions for high yields while using reduced enzyme loads in saccharification and fermentation processes. These methods increase the efficiency of enzymes and result in improved yields and composition of saccharification and fermentation end products. |
| US08563276B2 |
Method of enzyme cleavage of polysaccharides derived from algae
The invention relates to a method for enzyme cleavage of polysaccharides comprising a first sequence [→4)-β-D-GlcpA-(1→4)-α-L-Rhap3 sulphate-(1→]n and a second sequence [→4)-α-L-IdopA-(1→4)-α-L-Rhap3 sulphate-(1→]m, the first and second sequences respectively comprising two monosaccharide units connected by an osidic bond, wherein said method is such that: said polysaccharide sequences are provided; a microorganism capable of producing an enzyme substance of the lyase class is provided; and said enzyme substance is brought into contact with said polysaccharide sequences in such a way as to bring about cleavage of the osidic bond according to a β-elimination reaction. The invention is characterized in that a microorganism belonging to the bacteria of the Ochrobactrum genus is chosen for producing said enzyme substance. |
| US08563271B2 |
Antibodies specific for sclerostin and methods for increasing bone mineralization
Compositions and methods relating to antibodies that specifically bind to TGF-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by interfering with the interaction between a TGF-beta binding protein sclerostin and a TGF-beta superfamily member, particularly a bone morphogenic protein. Increasing bone mineral density has uses in diseases and conditions in which low bone mineral density typifies the condition, such as osteopenia, osteoporosis, and bone fractures. |
| US08563269B2 |
Modified antibody compositions, methods of making and using thereof
The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolysed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolysing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies. |
| US08563263B2 |
Enhancement of vanadium-containing phosphatase inhibitors
The present invention is directed to a composition comprising a vanadium-containing phosphatase inhibitor and a polyol. In the presence of the polyol the effect of the inhibitor is enhanced, even in the presence of chelating agents or reducing agents. The invention also concerns the use of the inventive composition for inhibiting a phosphatase, as well as kits comprising the composition. |
| US08563262B2 |
Permanent inactivation of nucleases
The present invention relates to the use of reagent for permanently inactivating nucleases wherein the reagent comprises an oxidizing agent, a protein denaturant and optionally a pH adjustor and to a method for permanently inactivating nucleases using said reagent. |
| US08563252B2 |
Methods for distinguishing between lung squamous carcinoma and other non small cell lung cancers
The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of specific types of nonsmall-cell lung cancers (NSCLC). The nucleic acid sequences can also be used for prognosis evaluation of a subject based on the expression pattern of a biological sample. |
| US08563249B2 |
Receptor gene screening for detecting or diagnosing cancer
Compositions and methods that use the body's natural secretory immune system in a new way against steroid hormone responsive tumors of the breast and prostate, as well as other glandular/mucus epithelial tissues such as colon, ovary, endometrium, kidney, bladder, stomach, pancreas and secretory pituitary gland are provided. Also provided are new ways of identifying carcinogenic, or potentially carcinogenic, bacteria in a tissue or body fluid to provide better anti-cancer therapies and preventatives than have been available previously. |
| US08563248B2 |
Compositions and methods for detection of colorectal cancer
We have identified a new variant of ileal bile acid binding protein (IBABP), designated IBABP-L, which is a biomarker for colorectal cancer. The transcript for IBABP-L arises from an alternative start site and includes three exons that are absent in IBABP. IBABP-L also shares part of a fourth exon with IBABP. The protein encoded by IBABP-L contains a deduced 49 residue N-terminal sequence that is not found in the IBABP protein. The present invention provides methods for diagnosing colorectal cancer and other compositions and methods based on this discovery. |
| US08563247B2 |
Kits for multiplexed nucleic acid analysis by capture of single-stranded DNA produced from double-stranded target fragments
A method of fragmentation of double stranded DNA is disclosed for use in nucleic acid analysis, notably in the multiplexed analysis of polymorphisms and mutations. The method produces a multiplicity of labeled sense and anti-sense fragments which are not complementary, and thus do not significantly re-anneal under conditions suitable for hybridization analysis (or capture-mediated elongation analysis) of the polymorphisms and/or mutations. The fragments display a desired or predicted length distribution. Cleavage sites can be selected such that the fragments are short, yet long enough to allow discrimination among fragments in an assay, and as a matter of statistical probability, such that the majority of fragments contain at least one labeled nucleotide to facilitate detection. |
| US08563245B2 |
Method for changing surface properties of a substrate from immobilized biomolecules
A method that modifies surface properties of a substrate by manipulating the immobilized biomolecules in mild biological condition. The manipulation comprised steps of: providing a biomolecule combined with at least one ssDNA combined with a first protein through an affinity binding tag; adding a second ssDNA conjugated with a second protein with a concentration greater than that of the first protein; and replacing the first protein on the ssDNA with the second protein through chemical competitive principle. The invention may comprise the steps with proper design of biotinylated DNA probes, the functionalized ssDNA nanotemplates can be recovered to its unbound state through a thermodynamic principle. |
| US08563243B2 |
Methods for affecting homology-directed DNA double stranded break repair
Disclosed herein are methods and composition for alteration of the presence, activity, or concentration of RNF138. Disclosed methods can be utilized to affect DNA double strand break repair. Methods and compositions can be utilized to alter RNF138 so as to prevent interaction between RNF138 and RAD51D. Specifically, methods can prevent RNF138-directed ubiquitylation of RAD51D, which is necessary for DNA double strand break repair. |
| US08563233B2 |
Blood substitute solution
The invention relates generally to blood substitute solutions and methods for using blood substitute solutions. The solutions may be used in a variety of applications and are particularly suited for use in applications where at least a portion of a host's blood is replaced with a substitute solution. |
| US08563230B2 |
Substrate processing method and substrate processing system
A solvent vapor is made to adhere efficiently to the surface of a resist pattern without using an ultraviolet irradiation process to improve processing accuracy, to reduce processing time and to suppress the diffusion of the solvent outside a substrate processing system.The surface of a resist pattern R formed on a semiconductor wafer W by an exposure process and a developing process is coated with water molecules m. A solvent vapor of a water-soluble solvent, such as NMP, is spouted on the surface of the resist pattern R coated with the water molecules m. A surface layer of the resist pattern R is swollen by the solvent vapor combined with the water molecules m to achieve a smoothing process. The water molecules m and the solvent s remaining on the resist pattern R on the wafer W after the smoothing process are removed by drying. |
| US08563222B2 |
Lithographic printing plate precursor
A lithographic printing plate precursor comprising an image-recording layer, said image-recording layer being photopolymerizable upon exposure to light having a wavelength of from 300 to 500 nm and containing a mixture of sensitizers. |
| US08563213B2 |
Methods for producing photosensitive microparticles
Described are various methods of producing non-aqueous dispersions of photosensitive polymeric microparticles, comprising: (a) preparing one or more aqueous dispersions of a polymerizable component, at least one of which contains a photosensitive material and, wherein the polymerizable components comprise at least one hydrophilic functional group and/or at least one hydrophobic functional group; (b) subjecting the dispersion of (a) to conditions sufficient to form microparticles; (c) at least partially polymerizing the polymerizable component; (d) combining the dispersion with an organic continuous phase comprising an organic solvent; (e) removing water from the dispersion such that the final water content of the non-aqueous dispersion is less than 30 percent by weight; wherein e) is performed before or after d); and (f) reacting any acid functional groups on the surface of the microparticles with a reactive material having at least one epoxy functional group, at least one thiocarbonylthio functional group, at least one alkoxyamine functional group, or at least one halide functional group. |
| US08563207B2 |
Toner binder and toner composition
Disclosed is a toner binder which has high storage stability and can achieve both of good low-temperature fixability and good hot offset resistance (a broadened fixing temperature range). Specifically disclosed is a toner binder comprising, as constituting units, a carboxylic acid component (x) and a polyol component (y), wherein the component (x) comprises two or more kinds of dicarboxylic acids (X1), selected from among aromatic dicarboxylic acids and ester-forming derivatives of the same, in a total amount of 80 mol % or more and a trivalent or higher polycarboxylic acid (x2); the component (y) comprises a polyester resin (P) which is constituted by a polyester resin (A) comprising 80 mol % or more of an aliphatic diol (y1) having 2 to 10 carbon atoms optionally together with a linear polyester resin (B); and the storage modulus at 150° C. [G′150] of resin (A) is 20000 dyn/cm2 or more and the ratio of [G′150] to the storage modulus as 180° C. [G′180] thereof, i.e., [G′150]/[G′180], is 15 of less. |
| US08563205B2 |
Magenta toner, developer, toner cartridge, process cartridge, image forming apparatus, and image forming method
Provided is a magenta toner containing toner particles that contain a colorant and a binder resin, wherein the colorant contains C.I. Pigment Red 57:1 and C.I. Pigment Yellow 180, a mass ratio between the C.I. Pigment Red 57:1 and the C.I. Pigment Yellow 180 being 99:1 to 10000:1, and wherein the binder resin contains a polyester resin that has a repeating unit derived from bisphenol A ethylene oxide represented by formula (1): wherein each of m and n independently represents an integer of 2 to 4. |
| US08563204B2 |
Hydroxygallium hydroxyaluminum phthalocyanine silanol containing photoconductors
A photoconductor containing an optional supporting substrate, a photogenerating layer, and at least one charge transport layer comprised of at least one charge transport component, and wherein the photogenerating layer contains a hydroxygallium phthalocyanine, a hydroxyaluminum phthalocyanine, a polymeric binder, and a silanol. |
| US08563199B2 |
Forming a bridging feature using chromeless phase-shift lithography
An elongated, chromeless, bridging feature is formed on a photolithography mask with an etching depth that causes a nominal phase difference of more than 180 degrees to energy passing through the photolithography mask. A corresponding photoresist feature is formed using the bridging feature. The phase difference may be chosen to minimize dimensional variation of the corresponding photoresist feature. |
| US08563196B2 |
Racked power supply ventilation
A ventilation system for a fuel cell power module is provided. The ventilation system includes a ventilation enclosure for evacuating fluids from the fuel cell power module, the ventilation enclosure having an air inlet for providing ingress of air to the enclosure. The ventilation system further concludes a ventilation shaft in fluid communication with the ventilation enclosure and an evacuation pump arranged to exhaust fluid from the ventilation enclosure to a desired location. |
| US08563192B2 |
Gas storage system
Among other things, a gas storage system includes a group of capsules and an activation element coupled to the group. The group of capsules are formed within a substrate and contain gas stored at a relatively high pressure compared to atmospheric pressure. The activation element is configured to deliver energy in an amount sufficient to cause at least one of the capsules to release stored gas. |
| US08563186B2 |
Systems and processes of operating fuel cell systems
The present invention is directed to systems and processes for operating molten carbonate fuel cell systems. A process for operating the molten carbonate fuel cell includes providing a hydrogen-containing stream comprising molecular hydrogen to a molten carbonate fuel cell anode; heating a hydrocarbon stream, at least a majority of which is comprised of hydrocarbons that are liquid at 20° C. and atmospheric pressure, with a heat source comprising an anode exhaust from the molten carbonate fuel cell anode; contacting at least a portion of the heated hydrocarbon stream with a catalyst to produce a steam reforming feed comprising gaseous hydrocarbons, hydrogen, and at least one carbon oxide; separating at least a portion of the molecular hydrogen from the steam reforming feed; and providing at least a portion of the separated molecular hydrogen to the molten carbonate fuel cell anode as at least a portion of the stream comprising molecular hydrogen. |
| US08563182B2 |
Anode water separator for a fuel cell system
An anode reactant recycling system for a fuel cell is disclosed, the system including a hollow main body, a bleed conduit, an injector, a water separator, and a hydrophilic porous media. The anode reactant recycling system for a fuel cell is configured to minimize a required number of components, eliminate the need for the anode heat exchanger, use a single valve for removal of condensate and reactant byproducts from the anode reactant recycling system, and provide an upstream volume for startup pressurization. |
| US08563181B2 |
Fuel cell, method for operating fuel cell and fuel cell system
A fuel cell system comprising a fuel cell having plural membrane-electrode assemblies and plates, fuel and oxidant humidifiers and heater exchanger. Heat exchange between a supply inlet and discharge outlet is carried out between first and second heat exchange mediums. Fuel gas and oxidant gas are directed to flow parallel to each other in the fuel cell. A circulation path is established through the fuel and oxidant humidifiers and the heat exchanger by interconnection among discharge outlet, heat exchanger, fuel and oxidant humidifiers, and inlet. |
| US08563180B2 |
SOFC hot box components
Various hot box fuel cell system components are provided, such as heat exchangers, steam generator and other components. |
| US08563172B2 |
Anode composition for lithium secondary battery and lithium secondary battery using the same
An anode composition for a lithium secondary battery includes an anode active material, a binder, and a conductive material. The active material includes a plurality of anode active material particles, each of which includes a core made of metal or metalloid allowing alloying or dealloying with lithium, or a compound containing the metal or metalloid; and a shell formed at an outer portion of the core and having Ketjen black. The conductive material includes carbon nano fiber. The anode composition uses a metal-based anode active material that may controls the volume expansion, and also uses conductive material with excellent dispersion so that the life characteristic of the battery may be improved. |
| US08563171B2 |
Electrode slurry improving rate performance of lithium battery and electrode of lithium battery
An electrode slurry which includes an active component, a conductive agent, a binder, an organic solvent, and octylphenolpoly(ethyleneglycolether)x, wherein x=9˜10. The active component, conductive agent, binder, organic solvent, and octylphenolpoly(ethyleneglycolether)x are mixed together. An electrode of lithium battery includes a current collector, and a layer of electrode material applied on a surface of the current collector, wherein a material of the layer of electrode material comprises an active component, a conductive agent, a binder, and octylphenolpoly(ethyleneglycolether)x, wherein x=9˜10. |
| US08563170B2 |
Negative electrode for alkaline storage battery, fabrication method thereof, and alkaline storage battery
A negative electrode for alkaline storage battery using a hydrogen-absorbing alloy includes fluorinated oil and a surface active agent. |
| US08563166B2 |
Electrochemical cell
In an electrochemical cell including a cathode 7, an anode 6, electrolyte 10, a hollow container 1 accommodating these members, and terminals extending from the inside to the outside of the hollow container 1, the terminals include a plurality of inner terminals 5a formed on the inner surface of the hollow container 1, a cathode outer terminal 5b1 formed on the outer surface of the hollow container 1, and an inner layer wire 5c formed on the inner layer of the hollow container 1 for commonly connecting the plurality of inner terminals 5a to the cathode outer terminal 5b1. |
| US08563162B2 |
Sealed battery
A sealed battery including: an electrode assembly 11 having multiple positive electrode substrates exposed at one end and negative electrode substrates exposed at the other end; and collectors 181 and collector receiving parts 183 that are resistance-welded on both sides of the multiple positive or the multiple negative electrode substrates or both, grooves 23 being formed around the resistance-welded portion of at least one of the collector 181 and the collector receiving part 183. Due to the spattered particles 26 generated during the resistance-welding being captured within the grooves 23, few particles burst into the inside of the electrode assembly 11 or into the outside. |
| US08563158B2 |
Lithium secondary battery
A lithium secondary battery includes a negative electrode, a positive electrode, and an electrolyte. The negative electrode includes a negative electrode current collector and a negative electrode active material layer. The negative electrode active material layer is provided on the negative electrode current collector. The negative electrode active material layer contains silicon and oxygen. A low oxygen content layer is provided in a portion of the negative electrode active material layer on the negative electrode current collector side, the low oxygen content layer having an oxygen content lower than that of the remaining portion of the negative electrode active material layer. The thickness of the low oxygen content layer is 25% or less of the thickness of the negative electrode active material layer. |
| US08563156B2 |
Center pin for secondary battery and secondary battery having the same
A center pin for a secondary battery and a secondary battery having the same, which optimizes a void volume of the secondary battery. The center pin is inserted into an electrode assembly of the secondary battery. The center pin has a longitudinal hole and includes a sealing member to seal a portion of the hole. The sealing member can include walls disposed within the center pin, to seal the portion of the hole. The sealing member can include a second center pin, which is inserted into the hole, to seal the portion of the hole. |
| US08563155B2 |
Battery module having excellent heat dissipation ability and battery pack employed with the same
Disclosed herein is a battery module constructed in a structure in which a plurality of plate-shaped battery cells are sequentially stacked in a module case, wherein each of the plate-shaped battery cells includes an electrode assembly of a cathode/separator/anode structure mounted in a battery case formed of a laminate sheet including a resin layer and a metal layer, a plurality of heat dissipation members are disposed at two or more interfaces between the battery cells, and a heat exchange member integrally interconnecting the heat dissipation members is mounted to one side of a stack of the battery cells, whereby heat generated from the battery cells during the charge and discharge of the battery cells is removed by the heat exchange member. |
| US08563152B2 |
Battery cell and monitoring device for assembled battery
A battery cell includes a power generating element, an electrode connected to the power generating element and configured to electrically connect the power generating element to outside, and an exterior member configured to cover the power generating element. The exterior member includes an insulating layer and a conductive layer, and the conductive layer includes a connection section electrically connected to the outs. |
| US08563150B2 |
Device for catalytic recombination of gases for alkaline batteries with shortened zinc anode
The invention concerns a device for catalytic recombination of gases for alkaline batteries with shortened zinc anode. The invention concerns a device for catalytic recombination of gases formed when charging a zinc anode alkaline battery, characterized in that it consists of a catalytic mass in contact with a crosslinked cellular metal foam serving as catalyst support and heat dissipating structure, said catalytic mass consisting of a mixture of carbon black including metal of platinum metals, and of a hydrophobic binder, the whole assembly being heat-treated to cause the hydrophobic binder of said catalytic mass to be sintered. Said device is advantageously connected to one of the terminals of the battery or to any other metal part constituting part of the cover of the battery case, so as to promote discharge of the calories produced. Such a device enables, in a long lasting manner during the charge-discharge cycles, limited internal pressure levels to be maintained, in particular in installations designed to operate without maintenance. |
| US08563149B2 |
Glass for data storage medium substrate, glass substrate for data storage medium and magnetic disk
To provide glass for a data storage medium substrate, whereby high heat resistance can be obtained.Glass for a data storage medium substrate, which comprises, as represented by mol percentage based on the following oxides, from 55 to 70% of SiO2, from 2.5 to 9% of Al2O3, from 0 to 10% of MgO, from 0 to 7% of CaO, from 0.5 to 10% of SrO, from 0 to 12.5% of BaO, from 0 to 2.5% of TiO2, from 0.5 to 3.7% of ZrO2, from 0 to 2.5% of Li2O, from 0 to 8% of Na2O, from 2 to 8% of K2O and from 0.5 to 5% of La2O3, provided that the total content of Al2O3 and ZrO2 (Al2O3+ZrO2) is at most 12%, and the total content of Li2O, Na2O and K2O (R2O) is at most 12%. |
| US08563147B2 |
Thin seeded Co/Ni multilayer film with perpendicular anisotropy for read head sensor stabilization
A hard bias (HB) structure for producing longitudinal bias to stabilize a free layer in an adjacent spin valve is disclosed and includes a composite seed layer made of at least Ta and a metal layer having a fcc(111) or hcp(001) texture to enhance perpendicular magnetic anisotropy (PMA) in an overlying (Co/Ni)X laminated layer. The (Co/Ni)X HB layer deposition involves low power and high Ar pressure to avoid damaging Co/Ni interfaces and thereby preserves PMA. A capping layer is formed on the HB layer to protect against etchants in subsequent process steps. After initialization, magnetization direction in the HB layer is perpendicular to the sidewalls of the spin valve and generates an Mrt value that is greater than from an equivalent thickness of CoPt. A non-magnetic metal separation layer may be formed on the capping layer and spin valve to provide an electrical connection between top and bottom shields. |
| US08563143B2 |
Organic electroluminescence device and method for fabricating the same
An organic electroluminescent (EL) device having improved efficiency and service life is provided. The organic electroluminescent device has a stack structure including an emitting layer and an electron-transport layer positioned between an anode and a cathode. The electron-transport layer includes a first layer adjacent to the emitting layer which may be a mixture of at least two materials, and a second layer adjacent to the cathode which may be a mixture of at least two materials. The mixture of at least two materials may be a mixture of an organic compound and one or more other organic compounds, or may be a mixture of a metal or inorganic compound and one or more other metal or inorganic compounds, or may be a mixture of one or more organic compounds and one or more metal or inorganic compounds. |
| US08563138B2 |
Adhesive and laminate made with the same
Provided is a polypropylene-based adhesive having an MFR of 2.7 g/10 min or higher, as measured at 230 ° C. under a load of 2.16 kg, comprising a composition which contains 5-95 parts by weight of (A) an isotactic polypropylene, 95-5 parts by weight of (B) a propylene/ethylene random copolymer, and 0-40 parts by weight of (C) an ethylene/propylene random copolymer, wherein 100 parts by weight of the composition is graft modified with 0.001-5 parts by weight of an unsaturated carboxylic acid and/or a derivative thereof, and wherein (B) is characterized by the following (i) to (iii): (i) the propylene/ethylene random copolymer (B) contains 60-90 mol % units derived from propylene and 10-40 mol % units derived from ethylene; (ii) the melting point (Tm) is in the range of 40-120 ° C.; and (iii) the molecular weight distribution (Mw/Mn) is in the range of 1.0-3.0. |
| US08563137B2 |
Composite material comprising two or more superimposed layers of woods
The invention relates to a composite material having two or more superimposed wood layers. Said layers are joined together by means of a one component polyurethane adhesive containing a prepolymer having free NCO groups and a wood having a volume fraction of libriform fibres in the region of between 50-70% is used. |
| US08563130B2 |
Anti-reflective coatings
A composition comprising polymeric particles having an average particle diameter from 0.5 to 30 μm and Vicker's scale hardness from 100 to 700 Kgf/mm2. The composition also contains a film-forming polymer having Tg no greater than 80° C. The average refractive index difference measured from 400 nm to 1100 nm between the polymeric particles and the film-forming polymer is no greater than 0.04. |
| US08563124B2 |
Carbon materials with interconnected pores
Methods of forming an electrically-conductive mesoporous carbon structure with interconnected pores or highly interconnected pores, and the resulting structures are described. The structure is formed by providing a mesoporous template, filling the mesopores with an organic precursor, polymerizing the organic precursor, pyrolyzing the polymerized organic precursor, and etching away the template. |
| US08563123B2 |
Three-dimensional netted structure having four molded surfaces
A three-dimensional netted structure having an upper surface, a lower surface, two side surfaces a left end surface, and a right end surface, including at least a plurality of filaments helically and randomly entangled and thermally bonded together, wherein the filaments are formed out of a thermoplastic resin by extrusion molding followed by cooling with a liquid; and the netted structure is four-surface molded, the upper surface, the lower surface and the two side surfaces being molded. An apparatus and a method for manufacturing the three-dimensional netted structure. |
| US08563121B2 |
Three-dimensional netted structure having four molded surfaces
A three-dimensional netted structure having an upper surface, a lower surface, two side surfaces a left end surface, and a right end surface, including at least a plurality of filaments helically and randomly entangled and thermally bonded together, wherein the filaments are formed out of a thermoplastic resin by extrusion molding followed by cooling with a liquid; and the netted structure is four-surface molded, the upper surface, the lower surface and the two side surfaces being molded. An apparatus and a method for manufacturing the three-dimensional netted structure. |
| US08563120B2 |
Microporous polyolefin multi layer film
The present invention relates to a multi-layered microporous polyolefin film for a battery separator and a method for preparing the same. The microporous multi-layered film of the present invention has a characteristics to have both the low shutdown temperature conferred by the polyethylene and the high melt fracture temperature conferred by the polypropylene and heat-resistant filler. In addition, it has the high strength and stability conferred by the micropores prepared under wet process and the high permeability and high strength conferred by the macropores prepared under dry process. Therefore, this multi-layered film can be used effectively to manufacture a secondary battery with high capacity and high power. |
| US08563118B2 |
Molded door facing blank and door including same
A door facing blank is provided that includes a central portion, first and second side portions adjacent to and integral with opposite sides of the central portion, opposite interior and exterior major surfaces, and a design element including a molded portion and an embossed portion. The side portions include stile-receiving areas that are substantially planar. The molded portion is molded in the central portion to establish a first groove portion in the exterior surface region of the central portion and a protrusion on the interior surface region of the central portion. The embossed portion is embossed in the first side portion to establish a second groove portion in the exterior surface region of the first side portion but no protrusion on the interior surface region of the first side portion. The first and second groove portions establish a continuous groove in the exterior major surface. |
| US08563115B2 |
Protective coatings for solid inkjet applications
This disclosure provides an aperture plate coated with a composition comprising a fluorinated compound and an organic compound selected from the group consisting of a urea, an isocyanate and a melamine. This disclosure also provides a process of applying a coating composition to an aperture plate, comprising adding a fluorinated compound, an organic compound selected from the group consisting of a urea, an isocyanate and a melamine, and an optional catalyst together in a solvent to form a coating composition, applying the coating composition to a base film, and curing the base film. This disclosure also describes replacing the aperture plate with polyimide film, where the polyimide film is coated with the above-described coating composition before a laser cutting process. |
| US08563113B2 |
Multi-laminate hermetic barriers and related structures and methods of hermetic sealing
A free-standing multi-laminate hermetic sheet includes a first carrier film, a hermetic inorganic thin film formed over the first carrier film, and a second carrier film formed over the hermetic inorganic thin film. A workpiece can be hermetically sealed using the multi-laminate sheet, which can be applied to the workpiece in a step separate from a formation step of either the multi-laminate sheet or the workpiece. |
| US08563111B2 |
Digital information media having adhesion promotion layer on a substrate
Disclosed is a digital information media having an adhesion promotion layer supported on a dummy (L1) substrate that enables secure bonding of the L1 layer, directly or indirectly, to the rest of the stack of layers in the digital information media. Certain materials including metals, metal alloys, or metalloids enhance adhesion between the adhesive layer and the L1. By applying an adhesion promotion layer of such materials on an inner surface of the L1, the bond between the adhesive and the adhesion promotion layer improves bonding and reduces a tendency for the L1 to delaminate from the rest of the stack. The tendency for breakage of the media at the juncture between the adhesion promotion layer and the adhesive is reduced, and incursion of moisture or oxygen through the interface between the adhesion promotion layer and the adhesive is inhibited. |
| US08563110B2 |
Optical data media containing an ultraviolet protection layer
Optical information media containing an ultraviolet protection layer are described. The protection layer will reduce or eliminate damage to the media's data layer and substrate. |
| US08563107B2 |
Container for medical products
A sanitary container has a hollow cavity for storing a product in cleanliness. A wall portion of the container has a laminated structure of an inner layer and an outer layer. The outer layer is made of a cyclic olefin polymer containing at least one pigment selected from the group consisting of C.I. Pigment Yellow 147, C.I. Pigment Yellow 180 and C.I. Pigment Yellow 181 and added therein. The inner layer is made of a cyclic olefin polymer free of the at least one pigment. The sanitary container is superb in pigment dispersion (ultraviolet ray blocking property), is free of troublesome contamination of its content with pigment particles, and is also excellent in impact resistance strength, gas barrier properties and interface bonding. |
| US08563096B2 |
Vertical film formation apparatus and method for using same
A method for using a vertical film formation apparatus includes performing a coating process inside the process container without product target objects present therein to cover an inner surface of the process container with a coating film, and then performing a film formation process inside the process container accommodating the holder with the product target objects placed thereon to form a predetermined film on the product target objects. The coating process alternately supplies the first and second process gases into the process container without turning either of the first and second process gases into plasma. The film formation process alternately supplies the first and second process gases into the process container while turning at least one of the first and second process gases into plasma. |
| US08563095B2 |
Silicon nitride passivation layer for covering high aspect ratio features
A method of forming a passivation layer comprising silicon nitride on features of a substrate is described. In a first stage of the deposition method, a dielectric deposition gas, comprising a silicon-containing gas and a nitrogen-containing gas, is introduced into the process zone and energized to deposit a silicon nitride layer. In a second stage, a treatment gas, having a different composition than that of the dielectric deposition gas, is introduced into the process zone and energized to treat the silicon nitride layer. The first and second stages can be performed a plurality of times. |
| US08563090B2 |
Boron film interface engineering
Methods of depositing boron-containing liner layers on substrates involve the formation of a bilayer including an initiation layer which includes barrier material to inhibit the diffusion of boron from the bilayer into the underlying substrate. |
| US08563086B2 |
Nano pattern formation
Nano structure patterning formation includes coating a part of a structural guide with a hydrophobic polymer, positioning the structural guide on a substrate, coating at least a part of the substrate with a film made of a block copolymer, and annealing the film made of the block copolymer to align the block copolymer. |
| US08563085B2 |
Precursor composition, methods of forming a layer, methods of forming a gate structure and methods of forming a capacitor
In a method of forming a layer, a precursor composition including a metal and a ligand chelating to the metal is stabilized by contacting the precursor composition with an electron donating compound to provide a stabilized precursor composition onto a substrate. A reactant is introduced onto the substrate to bind to the metal in the stabilized precursor composition. The stabilized precursor composition is provided onto the substrate by introducing the precursor composition onto the substrate after the electron donating compound is introduced onto the substrate. The electron donating compound is continuously introduced onto the substrate during and after the precursor composition is introduced. |
| US08563083B2 |
Methods of use of calcium hexa aluminate refractory linings and/or chemical barriers in high alkali or alkaline environments
A method for improving the insulating character/and or penetration resistance of a liner in contact with at least one of an alkali and/or alkaline environments is provided. The method comprises lining a surface that is subject to wear by an alkali environment and/or an alkaline environment with a refractory composition comprising a refractory aggregate consisting essentially of a calcium hexa aluminate clinker having the formula CA6, wherein C is equal to calcium oxide, wherein A is equal to aluminum oxide, and wherein the hexa aluminate clinker has from zero to less than about fifty weight percent C12A7, and wherein greater than 98 weight percent of the calcium hexa aluminate clinker having a particle size ranging from −20 microns to +3 millimeters, for forming a liner of the surface. This method improves the insulating character/and or penetration resistance of the liner. |
| US08563079B2 |
Plastic welding using fiber reinforcement materials
A method of reinforcing a thermoplastic part includes softening a portion of the thermoplastic part to form a pool, embedding fibers in the softened pool, and re-solidifying the pool embedded with fibers into a weld that strengthens the thermoplastic part. |
| US08563073B1 |
Methods for making fruit or vegetable extract from by-products
A process for making a fruit or vegetable extract including diffusing, screening, and pressing the pomace, and spinning, filtering and concentrating juice from the pomace to form an extract. Also, the pomace may be hydrated at various points during this process by water or by reclaimed condenser condensate. Also included is an extract made using the present inventive methods. |
| US08563072B2 |
Suspension containing hydronium stabilized colloidal silicic acid nanoparticles, formulation obtained from the said diluted suspension, powder obtained from the said de-hydrated suspension, compositions obtained from the said powder, preparation and use
The present invention relates to hydronium stabilized silicic acid nanoparticles, to the formulation obtained from the said diluted suspension, to the powder obtained from the said dehydrated suspension and to the preparation or dosage form obtained from the said suspension, formulation or powder, to their preparation and their use in all kinds of applications in the domains of food, medicine, pharmaceutics, cosmetics. The present invention provides a stable suspension of colloidal silicic acid nanoparticles having a pH lower than 0.9, a molar silicon concentration between 0.035 and 0.65, a free water concentration of at least 30% (w/v) and a ratio between hydronium ion and Si molar concentrations higher than 2 and preferably inferior to 4. The present invention further provides a method for preparing a stable suspension of colloidal silicic acid nanoparticles, which comprises the steps of providing an aqueous inorganic or organic silicon solution and quick mixing said aqueous inorganic or organic silicon solution with water containing a strong acidic compound at a temperature inferior at 30° C., preferably comprised between 1 and 25° C., to form a suspension of colloidal silicic acid nanoparticles having a pH lower than 0.9, stabilized by hydronium ions, the ratio between hydronium ions and Si molar concentrations being higher than 2 and preferably inferior to 4, for a molar silicon concentration between 0.035 and 0.65 and a free water concentration of at least 30% (w/v). |
| US08563069B2 |
Citrus pulp fiber dry blend systems
There is disclosed a dry blend system comprising citrus pulp fiber; and at least one component selected from the group consisting of hydrocolloids, lipids, carbohydrates, and proteins, wherein the dry blend system is capable of replacing the solids content in a finished food product. |
| US08563066B2 |
Sustained release of nutrients in vivo
Nutritional compositions delivered in vivo in a time controlled manner sustainable over long periods of time, provide enhancing athletic performance, increased hand/eye coordination and concentration on the task at hand. |
| US08563064B1 |
Corrugated crust
Disclosed is a proofed, cooked corrugated dough crust. The crust may include a top surface. Opposite the top surface is a bottom surface intended to be in contact with rollers of a roller grill. The bottom surface defines at least one parallel groove or at least one parallel ridge or both. A roller grill system for a proofed, cooked corrugated dough crust is also disclosed. The system may include a roller grill including a plurality of parallel rollers and spaces in an alternating series. At least one corrugated crust is also included. Any grooves rest on top of the rollers and any ridges are in the spaces between the rollers. A forming assembly system for proofing and cooking a corrugated dough crust is also disclosed. |
| US08563061B2 |
Method of inhibition of enzymatic browning in food using hypotaurine and equivalents
A method of inhibiting enzymatic browning in food involves the contacting of hypotaurine, a salt of hypotaurine or an equivalent of hypotaurine with the food. The hypotaurine can be provided from solution, an extract, or in solid form to a food that can loose its appeal to a consumer due to browning, such as cut fruits and vegetables, seafood, or a beverage. The antibrowning agent can be applied to the food by spraying, dusting, dipping, or dissolving, depending upon the form of the food to which the agent is added. |
| US08563056B2 |
Continuous method for the production of a yeast fermented beverage
The invention provides a continuous method for the production of a yeast fermented beverage, comprising consecutive continuous processing steps; wherein the gravity of a mash extract is maintained at more than 22° P; the gravity of the wort produced from the mash extract is maintained at more than 22° P until said wort is diluted with additional water; and the gravity of the diluted wort is within the range of 10-35° P; and wherein less than 30 wt. % of the fermentable sugars in the mash extract and wort are derived from fermentable sugars added after hydrolysis of the starch contained in the mash. The method offers the advantage that it is highly efficient in terms of energy consumption and extraction yields. Furthermore, it achieves extremely high productivity, especially in the operation of the brewhouse. |
| US08563055B2 |
Ensiling agent
The present invention relates to an ensiling agent for forage, as well as a method for ensiling forage by adding said ensiling agent to forage. |
| US08563049B2 |
Confectionery containing algae for the prevention of oro-dental infections
The present invention relates in general to a sweet. More specifically, the present invention relates to a sweet which provides beneficial effects on the teeth. The sweet according to the present invention promotes good oro-dental hygiene, and more particularly provides oro-dental care, and promotes and maintains healthy teeth and gums. It is characterized in that it contains microalgae and/or extracts of microalgae, and more particularly Chlorella and/or extracts of Chlorella. Finally, the present invention also relates to the use of a sweet, preferably a sugar-free sweet, containing Chlorella for promoting and maintaining good oro-dental health. |
| US08563047B2 |
Use of tea-derived, theaflavin enriched extract to increase exercise performance and reduce exercise recovery time
This invention provides various methods such as a method for enhancing athletic exercise performance of a subject by administering to the subject a composition comprising a physiologically acceptable carrier and an extract of tea, wherein the extract comprises at least 20% by weight of theaflavins and wherein the composition is administered in an amount effective to enhance the subject's athletic performance. |
| US08563046B2 |
Compositions, systems, and/or methods involving chlorine dioxide (“ClO2”)
Certain exemplary embodiments can provide a composition of matter comprising chlorine dioxide dissolved in acetic acid. When stored, a concentration of the chlorine dioxide in the composition of matter can be retained, with respect to an initial concentration of chlorine dioxide in said composition of matter, at, for example, greater than 30% for at least 28 days. Certain exemplary embodiments can provide a method comprising releasing chlorine dioxide from a composition comprising chlorine dioxide dissolved in acetic acid. |
| US08563039B2 |
Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
New biomaterials consisting of a combination of sulphated hyaluronic acid and gellan (as well as gellan that has not been associated with other polymers), to be used as a highly effective barrier to prevent post-surgical adhesions in abdominal, pelvic and, above all, spine surgery. |
| US08563038B2 |
Formulations and methods for the controlled release of active drug substances
Controlled release formulations and methods for preparing controlled release formulations for delivery of active drug substances are described herein. The formulations described herein may be employed to produce pharmaceutical compositions, such as controlled release dosage forms, adjusted to a specific administration scheme. |
| US08563037B2 |
Compositions and methods for joining non-conjoined lumens
Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique. |
| US08563033B1 |
Orally effective methylphenidate extended release powder and aqueous suspension product
An oral methylphenidate powder which is reconstitutable into a final oral aqueous sustained release formulation containing at least about 50%, or at least about 80% by weight water based on the total weight of the suspension, is provided. The powder is a blend containing a combination of an uncoated methylphenidate—ion exchange resin complex, a barrier coated methylphenidate—ion exchange resin complex—matrix, and a water soluble buffering agent such that upon formed into an aqueous liquid formulation, the formulation has a pH in the range of about 3.5 to about 5, or about 4 to about 4.5. Following administration of a single dose of the oral aqueous methylphenidate suspension, a therapeutically effective amount of methylphenidate is reached in less than one hour and the composition provides a twelve-hour extended release profile. |
| US08563032B2 |
Formulation and manufacturing process for calcium acetate capsules
The present invention relates to a pharmaceutical calcium acetate formulation and a process for making the same. In particular, the present invention relates to a calcium acetate capsule formulation comprising granules comprising calcium acetate along with other formulation adjuvants contained within a pharmaceutically acceptable capsule. |
| US08563027B2 |
Drug delivery through hydrogel plugs
An embodiment is a medical prosthesis for blocking or reducing tear flow through a punctum or canaliculus of a human eye and delivering a drug to the eye that comprises a dehydrated covalently crosslinked synthetic hydrophilic polymer hydrogel with dimensions to pass through a puncta lacrimali, with the dehydrated hydrogel absorbing physiological water to swell to at least 1 mm in cross-sectional width and conformably fit a canaliculus, with the hydrogel comprising a therapeutic agent dispersed through the hydrogel for release to an eye, with the hydrogel having a water content of at least about 50% by weight or volume when allowed to fully hydrate in vitro in physiological saline. |
| US08563025B2 |
Coatings for implantable medical devices
The present application teaches a coating having a biologically compatible compound conjugated to, or blended with, a polymer, wherein the polymer includes at least one olefin-derived unit and at least one unit derived from a vinyl alcohol, an allyl alcohol, or derivatives thereof. |
| US08563020B2 |
Compositions and methods for antimicrobial metal nanoparticles
Embodiments of the invention are directed to a composition having antimicrobial activity comprising particles comprising at least one inorganic copper salt; and at least one functionalizing agent in contact with the particles, the functionalizing agent stabilizing the particle in a carrier such that an antimicrobially effective amount of ions are released into the environment of a microbe. The average size of the particles ranges from about 1000 nm to about 4 nm. Preferred copper salts include copper iodide, copper bromide and copper chloride. Preferred functionalizing agents include amino acids, thiols, hydrophilic polymers emulsions of hydrophobic polymers and surfactants. |
| US08563019B2 |
Non-aqueous generation of chlorine dioxide
Disclosed is a method of making a non-aqueous chlorine dioxide solution by combining a chlorite salt and a non-aqueous carboxylic acid and the non-aqueous chlorine dioxide solution made by this method. Also disclosed are methods of disinfecting an object by applying the non-aqueous chlorine dioxide solution to the object and methods of disinfecting a liquid by adding the non-aqueous chlorine dioxide solution to the liquid. |
| US08563017B2 |
Disinfectant wet wipe
A disinfectant wet wipe that contains a germicidal solution and a nonwoven web material is provided. The germicidal solution includes a peracid and peroxide, which can act synergistically together to be efficacious against pathogens when exposed thereto. To stabilize the solution over a period of time (e.g., during storage), a variety of aspects of the wipe are selectively controlled in accordance with the present invention. For example, the nonwoven web material used in the wipe is formed from a synthetic polymer and is relatively hydrophobic in nature. Without intending to be limited by theory, it is believed that such materials possess a lower reduction potential for peroxides/peracids than cellulosic-based materials. In this manner, significant degradation of the peroxide or peracid contained in the germicidal solution is limited. To improve the wettability of the nonwoven web material, one or more surfactants are also employed in the germicidal solution. Besides improving wettability, the present inventors have surprisingly discovered that certain surfactants may also improve the stability of the solution. |
| US08563013B2 |
Systems and methods for delivering a fluid drug
Devices and methods for distributing a fluid, e.g., a fluid drug, are disclosed. Fluid-drug distribution can be advantageously utilized to help patients suffering from a disorder that affect fine motor skill usage, e.g., Parkinson's Disease. Some aspects are directed to dosing containers that are adapted to distribute one or more selected dosages of fluid from the container. In some instances, the containers are adapted to be operable by patients with hindered fingertip motor control to help dispense a fluid-drug, such as a fluid including carbidopa and levodopa. Other aspects are directed to a kit for distributing a fluid drug that can be stored with a longer shelf life in solid form. Also discussed herein are methods for distributing a fluid drug for treating a disorder such as Parkinson's Disease. |
| US08563010B2 |
Method for preventing mold formation by using hydrophobic materials, and mold-controlling agent for building parts
The present invention relates to a method for suppressing mold formation on building parts using hydrophobic substances, wherein a dispersion of hydrophobic particles having a mean particle diameter of from 0.005 to 5 μm in an organic dispersant is applied to the surface to be protected from mold attack and the dispersant is then removed, and to a composition for building parts which inhibits mold growth and comprises from 0.1 to 10% by weight of hydrophobic particles having a mean particle diameter of from 0.005 to 5 μm dispersed in an organic dispersant. |
| US08563009B2 |
Use of monomycolyl glycerol (MMG) as an adjuvant
Here we identify MMG and its alpha- and ketomycolic acid derivatives as highly bioactive lipids derived from M. bovis BCG (Copenhagen) capable of stimulating and activating human DC's at exceedingly low doses. In addition to their direct role as immunostimulators of human DC's we demonstrate their use in the development of a new generation of adjuvants suitable for human administration. We furthermore identify a number of highly active synthetic MMG analogues with great potential in cancer treatment, and for vaccine adjuvants against both infectious disease and disorders like Alzheimers disease. |
| US08563008B2 |
Polynucleotides and polypeptides involved in gestational malaria, and biological applications
The disclosure provides novel antigens involved in gestational malaria, and more particularly to polynucleotide and polypeptide sequences, conjugates, cloning vectors including the sequences for the preparation of immunogenic compositions and vaccines, antibodies, and to their for treating gestational malaria. Diagnostic methods and kits are described. |
| US08563007B1 |
Immunogenic compositions for the prevention and treatment of meningococcal disease
The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B. |
| US08562999B2 |
Formulations which stabilize and inhibit precipitation of immunogenic compositions
The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubing and the like. |
| US08562997B2 |
Methods of treating acute myeloid leukemia by blocking CD47
Methods are provided to manipulate phagocytosis of cancer cells, including e.g. leukemias, solid tumors including carcinomas, etc. |
| US08562989B2 |
Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization. |
| US08562987B2 |
Humanized anti-CD70 binding agents and uses thereof
Disclosed are CD70 binding agents, such as humanized anti-CD70 antibodies and fragments and derivatives, that exert a cytotoxic, cytostatic or immunomodulatory on CD70 expressing cells, as well as pharmaceutical compositions and kits comprising the antibody, fragment or derivative. Also disclosed are methods for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the CD70 binding agents or pharmaceutical compositions. |
| US08562981B2 |
Stable digestive enzyme compositions
Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing. |
| US08562980B2 |
Stable digestive enzyme compositions
Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing. |
| US08562979B2 |
Stable digestive enzyme compositions
Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing. |
| US08562975B2 |
Method for stabilizing reduced coenzyme Q10 and composition therefor
The present invention relates to a method for stabilizing reduced coenzyme Q10, which is useful as an ingredient in good foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc., and to a composition therefor. The composition comprises reduced coenzyme Q10, a fat and oil (excluding olive oil) and/or a polyol, and doesn't substantially inhibit the stabilization of reduced coenzyme Q10. Additionally, the composition is a reduced coenzyme Q10-containing composition which comprises reduced coenzyme Q10, a polyglycerol fatty acid ester, and a fat and oil and/or a polyol. |
| US08562973B2 |
Treatment of sarcoidosis using placental stem cells
Methods of treating individuals having sarcoidosis or a sarcoidosis-related disease or disorder using placental cells are described. Also describe are kits comprising placental stem cells or a composition thereof that can be used in methods of treating sarcoidosis or a sarcoidosis-related disease or disorder. |
| US08562972B2 |
Methods and compositions for treatment of bone defects with placental cell populations
Provided herein are methods of using adherent placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. Also provided herein are methods of differentiating the placental stem cells. Further provided herein are methods of using the placental stem cells to formulate implantable or injectable compositions suitable for administration to a subject. Still further provided herein are provides methods for treating bone defects with stem cells and compositions comprising stem cells. |
| US08562971B2 |
Reduction of risk diarrhoea
The use of a probiotic Lactobacillus rhamnosus and a probiotic Bifidobacterium longumin the manufacture of a medicament or therapeutic nutritional composition for administration to an infant during at least the first three months of life for the long-term prophylaxis of diarrhea in infants and young children. |
| US08562969B2 |
Treatment composition comprising physically disrupted tooth pulp and non-cultured stem cells
A medical implant comprising in components from a tooth and stem cells harvested from at least one tooth. Tooth stem cells may be harvested from the dental pulp of mammalian teeth, such as unerupted third molars in humans. After the stem cells are removed and isolated from the other teeth tissue, the hard tooth may be ground into a base material for the manufacture of a porous matrix into which the tooth stem cells can be added. Additionally, soft tissue from the harvested tooth may be used as a carrier scaffold for soft tissue applications such as meniscal or cartilage repair. |
| US08562967B2 |
Stable liquid formulations of G-CSF
Provided are pharmaceutical liquid formulations of G-CSF, which are stable over a long time period and substantially free of excipients, as well as ready-to-use syringes containing such formulations and corresponding kits. |
| US08562964B2 |
Polymalic acid-based multifunctional drug delivery system
A structured drug system that is useful for delivering a drug payload to a specific tissue or cell type is disclosed. The system is based on purified polymalic acid. This polymer isolated from natural sources is biocompatible, biodegradable and of very low toxicity. The polymer is extremely water soluble and contains a large number of free carboxyl groups which can used to attach a number of different active molecules. In the examples disclosed N-hydroxysuccinimide esters of the carboxyl groups are used to attach such molecules. The active molecules include monoclonal antibodies to promote specific cellular uptake and specific pro-drugs such as antisense nucleic acids designed to modify the cellular metabolism of a target cell. The pro-drugs are advantageously linked by a somewhat labile bond so that they will be released under specific conditions. In addition, the system contains amide-linked valine to encourage membrane disruption under lysosomal conditions. Polyethylene glycol groups are attached to extend the drug system's circulation half-life. In addition, fluorescent reported groups can be readily included to aid in visualizing and confirming drug system targeting. The drug system can deliver treatments for a wide range of diseases and is specially advantageous for treatment of neoplasms. |
| US08562962B2 |
Treatment and composition for achieving skin anti-aging benefits by corneum protease activation
Disclosed is a topical skin composition, and methods for its use, comprising a chemically compatible combination of one or more surfactants and at least one chelating agent, an algae extract, and magnesium ascorbyl phosphate, wherein the composition is formulated for topical application to skin. |
| US08562960B2 |
Cosmetic composition containing a polymer blend
The present invention relates to a cosmetic composition containing a unique polymer blend, which includes: (a) a first polymeric film-former having a first glass transition temperature ranging from about −20° C. to about 0° C.; (b) a second polymeric film-former having a second glass transition temperature that is at least 50° C. higher than the first glass transition temperature; and (c) a third cross-linked polymeric film-former. The cosmetic composition of the present invention can be applied to human skin or keratinous fibers for forming a film thereon with exceptionally long wearability, reduced flaking and smudge properties, and good removability by warm water. |
| US08562956B2 |
Method of making antiperspirant active compositions having SEC chromatogram exhibiting high SEC peak 4 intensity
A method of making an antiperspirant active composition comprising: heating an aqueous solution containing an aluminum salt having an aluminum to chloride molar ratio of about 0.3:1 to about 3:1, optionally with a buffer agent, at a temperature of about 50° C. to about 95° C. to reflux for a period of time of about 1 hour to about 5 hours to obtain an aluminum salt solution; adding an aqueous solution of an inorganic base to obtain an aluminum salt solution having an OH:Al molar ratio of about 2:1 to about 2.6:1 to obtain a pH adjusted aluminum salt solution having a pH of about 2 to about 5; and optionally adding an aqueous solution containing a zirconium compound to the pH adjusted aluminum salt solution to thereby obtain an aluminum-zirconium salt solution having a molar ratio of aluminum to zirconium of about 5:1 to about 10:1. |
| US08562955B2 |
Light-activated tooth whitening method
A method of whitening teeth comprises the steps of contacting a stained tooth surface with an organic metal-ligand complex and an oxidizing compound, and exposing the stained tooth surface to actinic radiation. |
| US08562953B2 |
Dendritic polymers and magnetic resonance imaging contrast agent employing the same
A dendritic polymer and a magnetic resonance imaging contrast agent employing the same. The magnetic resonance contrast agent includes the dendritic polymer according to the structure of SP-DZ-L)i)j or SP-DX-Z-L)i)j, wherein, S is cyclosilane moiety with j silicon oxygen residual groups, and j is not less than 2; P is CH2CH2Ol, and l is not less than 1; D is a C3-30 dendritic moiety having n oxygen residue, and n is not less than 3; X is C3-30 moiety having bi-functional groups; Z is a C3-20 moiety having a plurality of functional group; and L is a metal cation. |
| US08562952B2 |
Methods for manipulating satiety
Various embodiments of the invention disclosed herein include methods of inducing satiety a mammal in need thereof. Also disclosed are methods of inducing satiety in an obese mammal. Additionally disclose are method of suppressing appetite in a mammal in need thereof. Further disclosed are methods of treating obesity. The methods described herein involve the administration of serotonin, a serotonin agonist or a serotonin re-uptake inhibitor to the mammal. |
| US08562949B2 |
Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents
This invention relates to a method of imaging vesicular monoamine transporters and to labeled compounds and pharmaceutical compositions thereof, and methods of making labeled compounds useful in imaging vesicular monoamine transporters. This invention also relates to compounds, and methods of monitoring progression of a disease related to vesicular monoamine transporters. |
| US08562948B2 |
Somatostatin analogs with inhibitory activity to growth hormone release
Provided are therapeutic and diagnostic somatostatin analogs including radiotherapeutic and radiodiagnostic reagents, and methods of making and use thereof. |
| US08562947B2 |
Oxidized avidin with high residency time in the treated tissues
The present invention describes chemically modified avidins that have higher permanence in treated tissues compared to wild type avidin. Avidin oxidation is performed by periodate incubation in the presence of the low affinity ligand HABA which, occupying the biotin binding sites, prevents protein denaturation during the oxidation step. Periodate oxidation generates CHO groups from avidin mannose ring opening that, once injected, react with tissue NH2 residues to form stable Schiff's bases. The anchored avidins maintain the ability to bind biotinylated agents endowed of therapeutic activity, like radiolabeled biotins, stem cells and somatic cells, useful for brachytherapies like Intraoperative Avidination Radionuclide Therapy (IART®) or degenerative or genetic diseases. |
| US08562943B2 |
Quality control methods for oil-in-water emulsions containing squalene
Measurements of the squalene content in oil-in-water emulsions can be used as a way of checking for problems during production. In particular, it has been found that a drop in squalene content can indicate that filtration problems occurred. Testing the squalene content in the final lots is easier than investigating the characteristics of the filter, and so a squalene assay simplifies the quality control of oil-in-water emulsions. |
| US08562942B2 |
Molecular sieves and related methods and structure directing agents
Method for preparing molecular sieves and molecular sieves obtained thereby are described. The method includes preparing a reaction mixture, comprising a structure directing agent, at least one source of at least one oxide of a tetravalent element, optionally, one or more sources of one or more oxides selected from the group consisting of oxides of trivalent elements, pentavalent elements, and mixtures thereof, optionally, at least one source of an element selected from Groups 1 and 2 of the Periodic Table; and optionally, hydroxide ions or fluoride ions, and maintaining the reaction mixture under conditions sufficient to form crystals of the molecular sieve. In the method, various imidazolium cations are used as the structure directing element. |
| US08562935B2 |
Amplification of carbon nanotubes via seeded-growth methods
The present invention is directed towards methods (processes) of providing large quantities of carbon nanotubes (CNTs) of defined diameter and chirality (i.e., precise populations). In such processes, CNT seeds of a pre-selected diameter and chirality are grown to many (e.g., hundreds) times their original length. This is optionally followed by cycling some of the newly grown material back as seed material for regrowth. Thus, the present invention provides for the large-scale production of precise populations of CNTs, the precise composition of such populations capable of being optimized for a particular application (e.g., hydrogen storage). The present invention is also directed to complexes of CNTs and transition metal catalyst precurors, such complexes typically being formed en route to forming CNT seeds. |
| US08562932B2 |
Method of purifying silicon utilizing cascading process
The present invention relates to a method of purifying a material using a metallic solvent. The present invention includes a method of purifying silicon utilizing a cascade process. In a cascade process, as the silicon moves through the purification process, it contacts increasingly pure solvent metal that is moving through the process in an opposite direction. |
| US08562930B2 |
Dynamic oxidation of process gas
Hazardous process gases are heated to auto ignition temperatures by rods and cylinders in a heating chamber. The heated gases and oxygen mix in a combustion chamber, and the gases ignite and combust. Air is introduced to cool the hot combustion products. Particles are separated from the cooled gases. Pure non hazardous gases and air are exhausted. |
| US08562929B2 |
Selective catalytic reduction via electrolysis of urea
A method for producing ammonia suitable for use as a reductant in a combustion exhaust gas treatment system is provided that includes the electrolytic hydrolysis of urea under mild conditions. The ammonia generator, which includes an electrolysis apparatus including an electrolytic flow cell, an alkaline electrolyte composition, and a recirculation system, may be operatively coupled to an exhaust gas treatment system to provide an apparatus for reducing nitrogen oxides (NOx) and/or particulate in exhaust gases. |
| US08562927B2 |
Absorbent solution containing a breakdown inhibitor derived from thiazole or from oxazole and absorption process for acid compounds contained in a gaseous effluent
The degradation of an absorbent solution comprising organic compounds provided with an amine function in aqueous solution is reduced considerably in the presence of a small amount of degradation inhibiting additives whose structure comprises a 5-atom heterocycle composed of a nitrogen atom, a sulfur atom or an oxygen atom, and 3 carbon atoms, at least one of which is joined to a sulfur atom not belonging to the ring. The absorbent solution is employed for deacidifying a gaseous effluent. |
| US08562925B2 |
Arrangement and method for controlling the quantity of a reductant introduced into an exhaust line of an internal combustion engine
An arrangement for controlling injection of a reducing agent in an exhaust line of a combustion engine (1): An injection system (8-12) injects the reducing agent into the exhaust line (3). A first catalyst (13) reduces the amount of nitrogen oxides in the exhaust gases in the exhaust line (3) using the reducing agent. A second catalyst (14) downstream of the first catalyst (13) in the exhaust line (3) converts ammonia in the exhaust gases to nitrogen gas and nitrous oxide. A nitrous oxide sensor (17) monitors the amount of nitrous oxide in the exhaust line (3) downstream of the second catalyst (14). A control unit (10) of the injection system (8-12) adjusts the amount (q) of reducing agent injected into the exhaust line (3) if the sensor (17) detects that the amount of nitrous oxide is not within a selected range (A). |
| US08562924B1 |
Control of NO/NOx ratio to improve SCR efficiency for treating engine exhaust
Methods and systems for treating NOx-containing exhaust from an internal combustion engine. An exhaust aftertreatment system has at least a PM control device and a downstream selective reduction catalyst (SCR) device. By using a bypass line to divert engine-out exhaust around the PM control device, or by introducing NO or NO2 from a non-engine source, the NO/NOx ratio into the SCR device can be controlled to a desired ratio for improved SCR efficiency. |
| US08562922B2 |
Picolylamine resins
The present application relates to novel gel-type or macroporous picolylamine resins which are based on at least one monovinylaromatic compound and at least one polyvinylaromatic compound and/or a (meth)acrylic compound and contain tertiary nitrogen atoms in structures of the general formula (I) as functional group, where R1 is an optionally substituted radical from the group consisting of picolyl, methylquinoline and methylpiperidine, R2 is —CH2—S—CH2COOR3 or —CH2—S—C1-C4-alkyl or —CH2—S—CH2CH(NH2)COOR3 or —CH2—S—CH2—CH(OH)—CH2(OH) or or derivatives thereof or —C═S(NH2), R3 is a radical from the group consisting of H, Na and K, m is an integer from 1 to 4, n and p are each, independently of one another, a number in the range from 0.1 to 1.9 and the sum of n and p is 2 and M is the polymer matrix, a process for preparing them and their uses, in particular the use in hydrometallurgy and electroplating. |
| US08562921B2 |
Ethyl acetate production
A process for the production of high purity ethyl acetate from ethanol is described. The process involves reacting ethanol over a suitable catalyst in a reactive distillation column. The reactive distillation setup allows overcoming the reaction equilibrium for increased conversion of ethanol. Hydrogen is removed as the distillate and ethyl acetate is obtained as a bottoms product from the reactive distillation column. A feed of hydrogen at the bottom of the column and a suitable hydrogenation catalyst placed at the bottom of the column allows for a significant reduction of impurities such as butan-2-one and/or n-butyraldehyde in the ethyl acetate product. Adding side reactors to the reactive distillation column allows additional catalyst holdup for improved reactant conversion. |
| US08562919B2 |
Feces sampling container
It is to provide a device for sampling feces that enables an accurate and quantitative evaluation by decreasing the variations of feces sampling levels, wherein the confirmation of the presence or absence of feces sampling can be performed hygienically and simply from an outside of a container. A device for sampling feces comprising a feces sampling stick 10, a container body 20, and a fitting body (30, 40) fitted to the inner part of the container body; the feces sampling stick having a gripping part 11 and a stick part 12, being provided with a feces sampling part 14 at the end; the container body having an opening part to fit the fitting body on one side, and a bottom part 21 on the other side, wherein a feces-suspending liquid container part for preserving a liquid for suspending feces 22 is formed in a space between the lower part of the container body and the lower side of the fitting body; the fitting body having a tubular guide part 34 that enables introduction of the stick part of the feces sampling stick, a first leveling hole 35 to remove excess feces, and a second leveling hole 42 below the first hole for further removing excess feces; wherein a domain for detecting collected feces 39 is formed in a tubular guide part adjacent to the upper end of the first leveling hole. |
| US08562918B2 |
Universal sample preparation system and use in an integrated analysis system
The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft3. and can be a closed, portable, and/or a battery operated system. The system can be used to go from raw sample to analysis in less than 4 hours. |
| US08562915B2 |
Processes and apparatus for polymer finishing and packaging
Provided are apparatus and methods relating to the finishing line of a continuous solution polymerization plant. In one aspect, an apparatus includes a pelletizer having cooling liquid, e.g., water or aqueous solution, into which is added a pelletization aid. In another aspect, the apparatus comprises means to remove residual polymer particles from the pelletizer cooling liquid. In a further aspect, the apparatus comprises conduits of at least 50 m in length for carrying propellant cooling liquid from the pelletizer to a drying apparatus. The residence time of the pellets in the cooling liquid may be 10 seconds or more. In a further aspect, a drying apparatus is provided for the pellets which comprises first and second drying zones. In a further aspect, a pneumatic conveyor is provided for carrying pellets to a packaging apparatus. In a further aspect, a packaging apparatus is provided comprising a blender silo. |
| US08562914B2 |
Deodorizing system and method for use thereof
A system for producing a deodorizing or odor neutralizing fog includes a tank with an input port and an exit port, and a fogging portion located within the tank. A deodorizing or odor neutralizing liquid is added to the tank upon which the fogging portion is configured to float. Compressed air is input through said input port and is expelled on the deodorizing or odor neutralizing liquid through at least one nozzle located on the fogging portion, thereby vaporizing the deodorizing or odor neutralizing liquid. The vapor combines with the compressed air within the tank to form the deodorizing or odor neutralizing fog. |
| US08562911B2 |
Centrifugal rotor and method for using the same for delivering biological sample
Disclosed herein is a centrifugal rotor for delivering and analyzing biological sample. Chambers within the centrifugal rotor is used to split a biological sample, which comprises biological cellular components and biological fluids, into separate parts under centrifugal force after the biological sample being diluted, metered and distributed by the centrifugal rotor. |
| US08562910B2 |
Method and apparatus for analysis of poly (biphenyl chloride) in electrical insulating oil
An object of the present invention is to provide a method and an apparatus by which PCBs in insulating oil can be analyzed with high accuracy in a convenient, inexpensive, and rapid manner. The method for analyzing polychlorobiphenyls by measuring the concentration of polychlorobiphenyls in insulating oil comprises a step of, as pretreatment, bringing particles of a copolymer that contains divinylbenzene and a methacrylate organic monomer as monomer components into contact with insulating oil containing polychlorobiphenyls, so as to separate polychlorobiphenyls in insulating oil from oil content that is an impurity. The methacrylate organic monomer preferably has a diol type hydroxyl group. |
| US08562909B2 |
Device for decapping and recapping sample tubes
A decapping/recapping device for removing closures from sample tubes and for reclosing sample tubes with the same closures is presented. The device comprises individual closure holders, each holder comprising a passive closure gripper for holding a closure, at least one actuator for actuating the passive closure gripper when removing a closure from a tube or reclosing a tube with its respective closure and at least one tube gripper cooperating with the at least one actuator for biasing a tube and its closure away from each other when removing the closure and for biasing the tube and its closure towards each other when reclosing the tube. One actuator is coupled to one passive closure gripper of a closure holder when removing a closure from a tube or when reclosing a tube with its respective closure and is decoupled from a passive closure gripper when the closure holder is holding a closure. |
| US08562907B2 |
Hand sanitizer
A hand sanitizer (2) comprises: (a) a first part (14) comprising a chlorite solution and contained in a first dispenser (4) whereby it will be dispensed as a spray or jet of liquid; and (b) a second part (16) comprising an acid solution and contained in a second dispenser (6) whereby it will be dispensed as a second spray or jet of liquid; wherein the chlorite and the acid will react to provide chlorine dioxide when the first part is mixed with the second part; and wherein a mixture (18) of equal quantities of the first part and the second part contains at least 15% alcohol by weight; and wherein at least a part of the alcohol comprises 3-methoxy-3-methylbutan-1-ol (MMB). |
| US08562902B2 |
Direct smelting plant
A direct smelting plant for producing molten metal from a metalliferous feed material using a molten bath based direct smelting process is disclosed. The plant includes a plurality of crane access zones that are outboard of a gas delivery main to enable solids injection lances to be removed from and replacement lances to be positioned in openings in a side wall of a direct smelting vessel. The plant also includes a plurality of crane access zones that are inboard of the gas delivery main to enable gas injection lances to be removed from and replacement lances to be positioned in openings in the side wall of the vessel. |
| US08562900B2 |
Method of manufacturing and using rod-shaped proppants and anti-flowback additives
A sintered rod-shaped proppant and anti-flowback agent possesses high strength and high conductivity. The sintered rods comprise between about 0.2% by weight and about 4% by weight aluminum titanate. In some embodiments, the sintered rods are made by mixing bauxitic and non-bauxitic sources of alumina that may also contain several so-called impurities (such as TiO2), extruding the mixture, and sintering it. The starting material may optionally be milled to achieve better compacity and crush resistance in the final sintered rod. A fracturing fluid may comprise the sintered rods alone or in combination with a proppant, preferably a proppant of a different shape. |
| US08562898B2 |
Method for forming resin molded articles
A method for forming a resin molded article includes a step of extruding a thermoplastic resin intermittently at a predetermined speed from an extrusion slit, such that the resin droops downward in a shape of a sheet. The method further includes the steps of: feeding the extruded sheet-shaped resin downward by a pair of rollers; and forming the sheet-shaped resin with a mold. In the step of feeding the sheet-shaped resin, one of the rollers is pressed against the other, but not to the extent of crushing the sheet-shaped resin, regardless of the thickness of the sheet-shaped resin. In addition, a surface temperature of each of the rollers is set lower than a temperature of the sheet-shaped resin and within a predetermined temperature range. This method can prevent sliding contact between the rollers and the sheet, while preventing the sheet from being wound around the rollers. |
| US08562897B2 |
Method of and apparatus for making a three-dimensional object
An apparatus for making a three-dimensional object includes a table, a powdery layer-former that forms a powdery layer on the table, and an optical beam-irradiator that irradiates an optical beam on a predetermined region of the powdery layer to sinter the predetermined region of the powdery layer. A chamber for accommodating the table and the powdery layer-former and a lid for opening and closing an opening defined in the chamber at a location immediately above an optical beam-irradiating range are provided. The three-dimensional object is taken out from the chamber through the opening upon completion of the sintering, and the optical beam-irradiator is disposed at a position deviated from immediately above the optical beam-irradiating range to obliquely irradiate the optical beam on the powdery layer. |
| US08562891B2 |
Process and apparatus for ultraviolet nano-imprint lithography
A process and an apparatus for performing a UV nano-imprint lithography are provided. The process uses a polymer pad which allows a uniform application of pressure to a patterned template and an easy removal of a residual resin layer. The apparatus includes a tilt and decentering corrector which allows an accurate alignment of layers during the nano-imprint lithography process. |
| US08562890B2 |
Method for molding a cable structure
A headset can include a cable structure connecting non-cable components such as jacks and headphones. The cable structure can be constructed using a molding process. Different approaches can be used to ensure that a conductor bundle extending through the cable structure remains centered within the cable structure during the molding process. In some cases, a movable tube can be placed in the mold such that the conductor bundle is retained within the tube. As material is injected into the mold and reaches the tube, the tube can be displaced and progressively removed from the mold. Alternatively, the movable tube can be constructed such that the tube may combine with injected material to form a shell of the cable structure. In some cases, gates from which material is provided in the mold can be positioned and controlled to facilitate the injection of material in the mold while maintaining the centered position of the conductor bundle. |
| US08562885B2 |
Multilayer structures having annular profiles and methods and apparatus of making the same
Disclosed are multilayer film structures having annular profiles, and methods and apparatus of making the structures disclosed. The annular multilayer articles have a uniform thickness, at least four layers and comprise overlapped and non-overlapped circumferential areas; wherein the layer structure of the non-overlapped area is doubled in the overlapped layer. A method of making the structure includes providing a multilayer flow stream with at least four layers of thermoplastic resinous materials; feeding the multilayer flow stream to a distribution manifold of an annular die to form an annular multilayer flow stream; and removing the annular multilayer flow stream from the annular die to form the annular multilayer structure. Also disclosed is an apparatus, comprising: a feedblock, with optional layer multiplier, that provides a multilayer flow stream of at least four layers to the manifold of an annular die; and an annular die having at least one distribution manifold that extrudes a multilayer flow stream. |
| US08562877B2 |
Method for making carbon nanotube structure
A method for making a carbon nanotube structure is provided. The method includes the following steps. A carbon nanotube array on a substrate is provided. The carbon nanotube array is divided with a separating line to form a strip-shaped carbon nanotube array. A carbon nanotube film is pulled out from the strip-shaped carbon nanotube array. |
| US08562875B2 |
Adsorbent filter media for removal of biological contaminants in process liquids
Adsorbent filter media particularly suited for removal of biological contaminants in process liquids. A porous fixed bed of adsorbent material is formed, using only a granular adsorbent and a water-insoluble thermoplastic binder. The resulting composite filter allows for a higher amount of adsorbent with smaller adsorbent particles than conventional depth filters. Elimination of cellulose fiber, as well as the elimination of the thermoset binder, results in reduced contamination of the process liquid. |
| US08562872B2 |
Paste for solar cell electrode and solar cell prepared using the same
A paste for solar cell electrodes and a solar cell using the same, the paste including a conductive powder; glass frit; an organic vehicle; and metal oxide particles, the metal oxide particles having a nanometer scale particle size distribution having an average particle diameter (D50) of about 15 nm to about 50 nm and a micron scale particle size distribution having an average particle diameter (D50) of about 0.1 μm to about 2 μm. |
| US08562865B2 |
Method of producing M-C-N-O based phosphor
A method of producing an M-C-N-O based phosphor with reduced non-uniform emission and improved color purity is provided. The method of producing an M-C-N-O based phosphor comprising a group IIIB element (M), carbon (C), nitrogen (N) and oxygen (O) comprises: heating a mixture comprising a group IIIB element-containing compound and a nitrogen-containing organic compound to form a pyrolysate; disintegrating the resulting pyrolysate-containing product; and firing the disintegrated product. |
| US08562860B2 |
Method for activating and stabilizing dissolved hydrogen in water
A method for activating hydrogen molecules dissolved in water and stabilizing the concentration of the hydrogen molecules is provided. The method for activating and stabilizing hydrogen molecules dissolved in water is characterized by allowing hydrogen ions to coexist with the hydrogen molecules. |
| US08562857B2 |
Process for producing positive electrode active material particles for battery
A process of producing positive electrode active material particles for a battery, comprising a step of providing a slurry comprising resin particles, a cationic surfactant and/or a polyvinyl alcohol derivative, lithium complex oxide particles, and a polar solvent; removing the polar solvent from the slurry to give a composition; and firing the composition and at the same time, removing the resin particles from the composition, wherein the cationic surfactant is a quaternary ammonium salt, the polyvinyl alcohol derivative is a polyvinyl alcohol into which a quaternary ammonium salt group has been introduced or which has been substituted by a quaternary ammonium salt group, and the resin particles have an average particle size of 0.1 to 20 μm. |
| US08562855B2 |
Silicon etching liquid and etching method
In etching processing of silicon, in particular anisotropic etching processing of silicon in a manufacturing step of MEMS parts, an etching liquid having a long life of etching liquid and an etching method are provided by suppressing a lowering of an etching rate at the time of warming which is characteristic of a hydroxylamine-containing etching liquid.A silicon etching liquid which is an alkaline aqueous solution containing an alkali metal hydroxide, hydroxylamine and an inorganic carbonate compound and having a pH of 12 or more and which is able to anisotropically dissolve monocrystalline silicon therein, and an etching method of silicon using this etching liquid are provided. |
| US08562852B2 |
Piezoelectric ceramic, piezoelectric element comprising it, and piezoelectric device comprising piezoelectric element
According to a preferred embodiment, the piezoelectric ceramic includes a complex oxide having the composition represented by formula (1) or (2), and Mn at 0.2-1.2 mass % or 0.2-3 mass %, respectively, in terms of MnCO3. (Pb1-aA1a)TixZr1-x-y-z-b(Zn1/3A22/3)y(Yb1/2A21/2)zSnbO3 (1) (Pb1-aA1a)TixZr1-x-y-b(Zn1/3A22/3)ySnbO3 (2) [In formula (1), A1 represents at least one element selected from the group consisting of Ca, Sr and Ba, and A2 is at least one element selected from the group consisting of Nb, Ta and Sb, and includes at least Nb. In formula (2), A1 represents at least one element selected from among Ca, Sr and Ba, A2 represents at least one element selected from among Nb and W, and A2 includes at least Nb.] |
| US08562851B2 |
Ferrite material and electronic component
A ferrite material and an electronic component which employs sintered ferrite formed from the ferrite material. The ferrite material is obtained by adding, as minor ingredients, 0.06-0.50 parts by weight of bismuth oxide in terms of Bi2O3, 0.11-0.90 parts by weight of titanium oxide in terms of TiO2, and 0.06-0.46 parts by weight of barium oxide in terms of BaO to a ferrite powder comprising iron oxide, copper oxide, zinc oxide, and nickel oxide as major ingredients. The weight ratio among the bismuth oxide, the titanium oxide, and the barium oxide is as follows: when the proportion of the bismuth oxide in terms of Bi2O3 is taken as 1.00, then the proportion of the titanium oxide in terms of TiO2 is 1.08-2.72 and that of the barium oxide in terms of BaO is 0.72-1.20. |
| US08562848B2 |
End point detecting method of metal etching and device thereof
Disclosed is an end point detecting method of metal etching and a device thereof. The end point detecting method of metal etching comprises: performing scan to a metal film to acquire a proportion of a transparency area of the metal film in a scanned area; judging whether the proportion of the transparency area reaches a predetermined value or not; and confirming a current etching time of the metal film as an etching end point time when the predetermined value is reached. The device comprises an acquirement module, a judgment module and a confirmation module. The acquirement module performs scan to the metal film to acquire the proportion of the transparency area. The judgment module judges whether the proportion reaches the predetermined value or not. The confirmation module confirms the current etching time of the metal film as the etching end point time when the proportion reaches the predetermined value. |
| US08562845B2 |
Ink jet print head and method of manufacturing ink jet print head
The present invention provides an ink jet print head having a channel shape that meets an intended purpose, and a method for manufacturing the ink jet print head. In the method for manufacturing the ink jet print head, an SIO SOI substrate is prepared which has a first silicon layer, a second silicon layer, and an insulating layer. A sacrifice layer is formed on the first monocrystal silicon layer. An etching stop layer is formed over the sacrifice layer. An energy generating element is formed on a surface of the SOI substrate. Etching is performed on the second silicon layer and the insulating layer to form an ink supply port. The supply port is formed by etching. The first silicon layer is etched to form a liquid channel. A part of the etching stop layer is removed to form an ejection port. |
| US08562844B2 |
Methods using block co-polymer self-assembly for sub-lithographic patterning
Block copolymers can be self-assembled and used in methods as described herein for sub-lithographic patterning, for example. The block copolymers can be diblock copolymers, triblock copolymers, multiblock copolymers, or combinations thereof. Such methods can be useful for making devices that include, for example, sub-lithographic conductive lines. |
| US08562843B2 |
Integrated circuit method with triple patterning
The present disclosure provides one embodiment of an integrated circuit (IC) design method. The method includes receiving an IC design layout having a plurality of IC features. The method includes identifying, from the IC design layout, simple features as a first layout wherein the first layout does not violate design rules; and complex features as a second layout wherein the second layout violates the design rules. The method further includes generating a third layout and a fourth layout from the second layout wherein the third layout includes the complex features and connecting features to meet the design rules and the fourth layout includes trimming features. |
| US08562842B2 |
Methods of fabricating nanoimprint stamp
A method of fabricating a nanoimprint stamp includes forming a resist pattern having a nano size width on a stamp substrate by performing imprint processes repeatedly. In the imprint processes, resist layers that are selectively etched are sequentially used. The stamp substrate is etched using the resist pattern as an etch mask. |
| US08562839B2 |
Desalination system and process
The present invention pertains to an effective system and method for reducing or eliminating the formation of scale in desalination systems. The system utilizes at least one pair of electrodes in direct contact with a liquid to induce an oscillating electric field directly in a portion of the liquid or a liquid stream of the desalination system. The electric field is capable of inducing bulk precipitation of ions, minerals, salts, particulates, contaminants or a combination thereof from the liquid stream. |
| US08562837B2 |
Backflush methods and devices for chromatography
Certain embodiments described herein are directed to chromatography systems that include a microfluidic device and that implement one or more methods to direct sample to a desired fluid flow path. The methods can be used to backflush a sample to a desired fluid flow path to select certain analytes within a sample. |
| US08562836B2 |
Graft copolymers, methods for grafting hydrophilic chains onto hydrophobic polymers, and articles thereof
The present invention relates to synthetic methods for grafting hydrophilic chains onto polymers, particularly hydrophobic polymers such as poly(vinyl chloride) (PVC), poly(vinylidene fluoride) (PVDF), and chlorinated polypropylene (cPP). Resulting polymers include comb polymers which can have a microphase-separated structure of hydrophilic domains provided by the hydrophilic chains. Articles prepared from these comb polymers, particularly derived from PVDF, include membranes for water filtration in which the hydrophilic domains provide a pathway for water transport. PVC can be plasticized by grafting the PVC with hydrophilic chains. In addition, such articles, particularly articles having biomedical applications, can display anti-thrombogenic properties. |
| US08562833B2 |
Subsurface wave power generation water purification systems and methods
A subsurface wave action harnessing system includes a seabed mounting plate adapted for securing to a seabed, a wing having generally opposed first and second wing surfaces extending between a first and second wing ends, the second wing end being pivotably mounted to the seabed mounting plate such that pivoting motion about a pivot axis generally parallel to the mounting plate is imparted to the wing by subsurface wave action acting on the first and second wing surfaces, and a drive arm pivotably connected to the wing to convert the pivoting motion into reciprocal motion. An electrical generator, water purifier or other wave action load can be driven by the drive arm. |
| US08562832B2 |
Three-stage slurry processing apparatus and method
A three-stage separator system for separating the solids and liquids from a slurry includes a first stage having an inclined housing defining a liquid channel. A slot sieve is disposed over an open surface of the channel. A mechanical vibrator assembly imparts mechanical vibration to a vibration zone of the slot sieve. A slurry delivery apparatus delivers the slurry to the slot sieve. A second stage includes an inclined conveyer positioned to convey partially-separated solids and includes a drive mechanism driven at a speed to cause the partially-separated solids to tumble as they are transported up the conveyor. A third stage includes a press positioned to accept partially-separated solids passing out of the tunnel press restrictor. |
| US08562829B2 |
Magnetic separation apparatus and waste water treatment apparatus
A magnetic separation apparatus comprising: a separation vessel into which waste water containing a coagulated magnetic floc is supplied; a drum separator that is provided in the separation vessel and adsorbs the magnetic floc with a magnetic force while being rotated; a scraper that is abutted against a surface of the separator and scrapes the magnetic floc adsorbed by the surface of the separator; a scraper guide that is connected to the scraper and discharges the magnetic floc scraped by the scraper; and a scraping brush that scrapes the magnetic floc scraped by the scraper from the scraper and guides the magnetic floc to the scraper guide, wherein a lower portion of the separator is submerged in the waste water in the separation vessel, a rotational direction of the separation vessel in the waste water is set to the same direction as a flow direction of the waste water flowing in the separator, and a rotational direction of the scraping brush is set to a direction opposite to the rotational direction of the separator. |
| US08562828B2 |
Wastewater treatment apparatus
A wastewater treatment apparatus (10) that treats the wastewater containing persistent substances, according to the present invention, includes a wastewater treatment bath (12) for treating a wastewater (11), an oxidizing reagent adding unit (14) for adding an oxidizing reagent (13) in the wastewater treatment bath (12), and an alkaline reagent adding unit (16) for adding an alkaline reagent (15) in the wastewater treatment bath (12). By making the wastewater in the wastewater treatment bath (12) in the alkaline condition, it is possible to completely decompose the persistent substances in the wastewater by the oxidation treatment using an oxidizing reagent. |
| US08562820B2 |
Sulfide scavenger
1,3,5-(2H2,4H2,6H2)tripropanediamine N,N,N′,N′,N″,N″ hexamethyl is used to scavenge sulfur compounds from hydrocarbons. A novel method of making the triazine comprises autocondensing (CH3)2NCH2CH2CH2N═CH2. |
| US08562817B2 |
Hydrocarbon composition
A hydrocarbon composition is provided containing: at least 0.05 grams of hydrocarbons having boiling point in the range from an initial boiling point of the composition up to 204° C. (400° F.) per gram of the composition; at least 0.1 gram of hydrocarbons having a boiling point in the range from 204° C. up to 260° C. (500° F.) per gram of the composition; at least 0.25 gram of hydrocarbons having a boiling point in the range from 260° C. up to 343° C. per gram of the composition; at least 0.3 gram of hydrocarbons having a boiling point in the range from 343° C. up to 510° C. per gram of the composition; and at most 0.03 gram of hydrocarbons having a boiling point of greater than 538° C. per gram of the composition; at least 0.0005 gram of nitrogen per gram of the composition, wherein at least 30 wt. % of the nitrogen in the hydrocarbon composition is contained in nitrogen-containing hydrocarbon compounds having a carbon number of 17 or less as determined by GC-GC nitrogen chemiluminscence. |
| US08562816B1 |
Tank cleaning system and apparatus
A method for treating crude oil and petrochemical product tank bottoms treats the tank bottoms sludge with a paraffin modifier that converts the tank bottom sludge, in the presence of a hydrocarbon diluent (cutter stock) and heat, into three separate phases. The resulting three phase separation is stable enough that there is no need for the use of any mechanical equipment such as centrifuges or decanters to enhance the separation. |
| US08562815B2 |
Glucose sensor having titanium dioxide-graphene composite
Provided is a glucose sensor including a titanium dioxide-graphene composite having a porous structure. More particularly, the glucose sensor includes a working electrode having the titanium dioxide-graphene composite having the porous structure and an enzyme to provide features that allow a current flow to be excellent, a current to be sensitively changed depending on a change in electric potential, sensitivity to be high, and a low voltage characteristic to be excellent. |
| US08562810B2 |
On site generation of alkalinity boost for ware washing applications
Methods for enhancing alkalinity and performance of ash-based detergents are disclosed. Nonhazardous ash-based detergent alkalinity is enhanced through increasing the ratio of sodium hydroxide to ash-based alkalinity. Methods according to the invention do not require the addition of chemical ingredients, do not generate additional waste streams and use the entirety of the ash-based detergent. The methods according to the invention provide alkalinity-enhanced detergent use solutions that are sufficiently concentrated for adequate cleaning capability while only requiring minimal amounts of the use solution to be dispensed for an in situ cleaning process. |
| US08562806B2 |
Electrochemical biosensor arrays and instruments and methods of making and using same
Improved electrochemical biosensor arrays and instruments are disclosed herein. Methods of making and using the electrochemical biosensor instruments are also disclosed. An electrochemical biosensor array can include an array of microelectrodes disposed on a substrate. Each microelectrode can include a conducting electrode material disposed on a portion of the substrate, a first polymeric layer disposed on at least a portion of the conducting electrode material, a second polymeric layer disposed on at least a portion of the first polymeric layer, and a capture molecule that is in physical communication with the second polymeric layer. |
| US08562800B2 |
Plasma generating apparatus and plasma processing apparatus
A plasma processing apparatus using a plasma generating apparatus by which droplets mixed in plasma can be efficiently removed and surface processing precision can be improved in film formation wherein high purity plasma is used. A droplet removing portion arranged in a plasma advancing path is composed of a straight plasma advancing tube (P0) connected to a plasma generating portion (A); a first plasma advancing tube (P1) connected to the straight plasma advancing tube (P0) in a bent manner; a second plasma advancing tube (P2) connected to a finishing end of the first plasma advancing tube (P1) by being inclinedly arranged at a predetermined inclination angle with respect to the tube axis of the first plasma advancing tube; and a third plasma advancing tube (P3), which is connected to the finishing end of the second plasma advancing tube (P2) in a bent manner and discharges plasma from a plasma outlet. |
| US08562798B2 |
Physical vapor deposition plasma reactor with RF source power applied to the target and having a magnetron
A physical vapor deposition reactor includes a metal sputter target, a D.C. sputter power source coupled to the metal sputter target and a wafer support pedestal facing the metal sputter target. A movable magnet array is adjacent a side of the metal sputter target opposite the wafer support pedestal. A solid metal RF feed rod engages the metal sputter target and extends from a surface of the target on a side opposite the wafer support pedestal. A VHF impedance match circuit is coupled to an end of the RF feed rod opposite the metal sputter target and a VHF RF power generator coupled to said VHF impedance match circuit. Preferably, the reactor of further includes a center axle about which the movable magnet array is rotatable, the center axle having an axially extending hollow passageway, the RF feed rod extending through the passageway. |
| US08562797B2 |
Electrochemical sensors
An electrode for use in a electrochemical sensor comprises carbon modified with a chemically sensitive redox-active compound, excluding an electrode based on carbon having derivatised thereron two redox-active species wherein at least one of said species is selected from anthraquinone, phenanthrenequinone and N,N′-diphenyl-p-phenylenediamine (DPPD). The invention further provides a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material; and a counter electrode, wherein the ratio of the surface area of the working electrode to the surface area of the counter electrode is from 1:10 to 10:1. Also provided is a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material, and a counter electrode, wherein the area of the working electrode is from 500 μm2 to 0.1 m2. The uses of these electrodes and sensors are also described. |
| US08562792B2 |
Vapor and liquid flow control in a dividing wall fractional distillation column
Dividing wall fractional distillation columns and methods of operating these columns with greater flexibility, especially in terms of the ability to adjust the composition of the heartcut, intermediate or sidecut product fraction, are described. In particular, this composition may be advantageously “biased” toward higher or lower molecular weight components, depending on operating needs. Changes in feedstock composition may also be managed more effectively. These benefits are obtained by varying the flow rate of vapor and liquid to each side of the dividing wall. The vapor flowrate rising from an undivided portion of the column interior below the dividing wall is varied to the feed and/or product sections on opposite sides of the dividing wall. Also, the liquid flowrate falling from an undivided portion of the column interior above the dividing wall is varied to the feed and/or product sections on opposite sides of the dividing wall. |
| US08562791B2 |
System for decontaminating water and generating water vapor
A system and method for decontaminating water and generating water vapor includes introducing contaminated water in to a vessel. The water is moved through a series of rotating trays alternately separated by stationary baffles so as to swirl and heat the water to effect the vaporization thereof to produce a vapor having at least some of the contaminants separated therefrom. The vapor is removed from the vessel for condensing apart from the separated contaminants and the remaining water. The vapor may be passed through a turbine connected to an electric generator. Sensors in a controller may be employed to adjust the speed of rotation of the trays or water input into the vessel in response to the sensed conditions. The treated water may be recirculated and reprocessed through the vessel to increase the purification thereof. |
| US08562790B2 |
Wet-end manufacturing process for bitumen-impregnated fiberboard
A process for manufacturing fiberboard by preparing a fiber slurry mixture including containing cellulose fibers and water then atomizing a liquid bituminous material, such as asphalt. The liquid bituminous material is atomized by mixing it with a pressurized gas, such as compressed air, forming a mist comprising droplets of bituminous material having a diameter between 20 microns and 50 microns. A water spray solidifies the bituminous material droplets thereby forming bituminous particles which fall into the fiber slurry within the spray chamber. From there the slurry is sheared, dewatered, and dried, forming a finished fiberboard. |
| US08562788B2 |
Wet-end manufacturing process for bitumen-impregnated fiberboard
A process for manufacturing fiberboard by preparing a fiber slurry mixture including containing cellulose fibers and water then atomizing a liquid bituminous material, such as asphalt. The liquid bituminous material is atomized by mixing it with a pressurized gas, such as compressed air, forming a mist comprising droplets of bituminous material having a diameter between 20 microns and 50 microns. A water spray solidifies the bituminous material droplets thereby forming bituminous particles which fall into the fiber slurry within the spray chamber. From there the slurry is sheared, dewatered, and dried, forming a finished fiberboard. |
| US08562781B2 |
Method for treating an optical lens for the edging thereof
The present invention relates to a method for treating an optical lens coated on at least one of the main surfaces thereof with a hydrophobic and/or oleophobic external coating, to make it capable of undergoing an edging process, comprising a step of depositing onto at least one part of the hydrophobic and/or oleophobic external coating a temporary adhesive composite film, said adhesive composite film comprising a pre-formed film, one main surface of which is coated with a pressure-sensitive adhesive layer, said adhesive layer directly contacting the hydrophobic and/or oleophobic coating, the pre-formed film modulus of elasticity in tension E′ being higher than or equal to 4200 MPa, and the rupture stress of the assembly composed of said adhesive film bonded to a polycarbonate specimen coated with a fluorinated silane layer, measured under tensile stress in accordance with the shear strength evaluation standard NF EN 1465, being higher than or equal to 0.05 MPa.The present invention further relates to an edging method and to a lens capable of undergoing a successful edging process. |
| US08562778B2 |
Tape adhering apparatus and tape adhering method
A tape adhering apparatus and a tape adhering method for adhering an ACF tape formed from an anisotropic conductive film to a target adhering area on a substrate are disclosed. It is an objective of the invention to provide a tape adhering apparatus and a tape adhering method that enable shortening of a time consumed by operation for adhering one cut piece of an ACF tape. According to the present invention, the separator is peeled from the cut piece of the ACF tape by letting the tape conveyor means convey the tape member in synchronism with the transfer action of the transfer base and thereafter a cut portion of the ACF tape to be next adhered is placed at the cutting position of the tape cutting means by letting the tape conveyor means continually convey the tape member in the forward conveyance direction. |
| US08562777B2 |
Method and apparatus for continuously forming dye sublimation images in solid substrates
A method for forming a dye sublimation image in a substrate with a dye carrier having an image formed thereon of a sublimatic dyestuff is provided. The image of the dye carrier is placed against a first surface of the substrate. The substrate and dye carrier are conveyed along a path with a first part and a second part. A continuous pressure is provided against the first surface of the substrate in the first part and second part of the path and therebetween. The dye carrier is heated to a sublimation temperature in the first part of the path. The dye carrier is then cooled to a depressure temperature in the second part of the path. |
| US08562771B2 |
Joints having improved sealability, lubrication and corrosion resistance
Embodiments of the present disclosure provide systems and methods for assembly of tubular joints which overcome the drawbacks and limitations of conventional joints. In certain embodiments, the tubular joints may comprise threaded joints used in oil exploration. Joints may be assembled using a combination of a) position control, b) specific production tolerances for thread parameters, and c) coatings applied on threaded areas of the joint. In further embodiments, the tubular joints may have no torque shoulder and/or metal to metal seals. In additional embodiments, the joints may be further assembled and disassembled several times without application of dope or grease and exhibit enhanced sealability. Beneficially, embodiments of the present disclosure may provide high tolerance, precisely assembled joints that provide improved performance (e.g., mechanical performance, sealability, corrosion resistance, lubrication) and reliability over non-premium connections without the expense associated with premium connections. |
| US08562770B2 |
Frame seal methods for LCD
A method for providing a bonded glass component for use in an LCD display. A frame is sealed to a glass component. A barrier coat is then applied to the sealant. An adhesive is poured over the entirety of the glass component and the frame. Starting at one edge of the glass component a second glass component is lowered down until an adhesive wave progresses across the glass component, until the second glass component in position. |
| US08562764B2 |
Copper alloy tube for heat exchangers
A copper alloy tube according to the present invention includes Sn 0.1 to 2.0 mass %, P 0.005 to 0.1 mass %, S 0.005 mass % or less, O 0.005 mass % or less, and H 0.0002 mass % or less, and the remainder has a composition consisting of Cu and unavoidable impurities. And, as is annealed, the copper alloy tube has the following characteristics: a tensile strength in the longitudinal direction of the copper alloy tube is 250 N/mm2 or more; an average grain diameter is 30 μm or less when measured in the direction perpendicular to the thickness direction of the tube, in the cross section perpendicular to the tube axis; and assuming that a tensile strength in the longitudinal direction of the copper alloy tube is σL, and a tensile strength in the circumferential direction of the same is σT, σT/σL>0.93 holds. [With such structure, the copper alloy tube can have a sufficiently high pressure-resistant breaking strength (breaking pressure) without deteriorating its bending workability due to an unnecessarily enhanced tensile strength, and further is excellent in its bending workability and heat resistance.] |
| US08562763B2 |
High strength α+β type titanuim alloy
A high strength α+β-type titanium alloy, containing, by mass %, 4.4% to less than 5.5% of Al, 1.4% to less than 2.1% of Fe, and 1.5 to less than 5.5% of Mo and including, as impurities, Si suppressed to less than 0.1% and C suppressed to less than 0.01% and a balance of Ti and unavoidable impurities. |
| US08562761B2 |
Steel
Steel is described having a chemical composition, in weight-%, of 0.3 to 0.5% carbon (C), from traces to a max. of 1.5% silicon (Si), 0.2 to 1.5% manganese (Mn), 0.01 to 0.2% sulfur (S), 1.5 to 4% chromium (Cr), 1.5 to 5% nickel (Ni), 0.5 to 2% molybdenum (Mo), which at least partially may be replaced by twice as much tungsten (W), 0.2 to 1.5% vanadium (V), from traces to a max. of 0.2% rare earth metals, and a balance essentially of only iron, impurities and accessory elements in normal amounts. In addition, a method for manufacturing a blank of the steel and a process for manufacturing a cutting tool body or holder for cutting tools of the steel is described. |
| US08562754B2 |
Dishwasher with programmable stop time
A dishwasher includes a tub having a door that provides access to the tub. The door has a handle which extends a top surface of the door beyond a front surface of the door. A touchscreen panel is mounted to the top surface of a door to provide a user interface. The user interface includes a carrousel of icons via which a user may select a wash cycle. The user interface further includes a programmed delay interface via which a user may specify a desired start time and/or stop time for the wash cycle. The user interface may further provide the user with usage guidance to aid the user in the usage of the dishwasher. |
| US08562751B2 |
Dry cleaning method of substrate processing apparatus
A dry cleaning method of a substrate processing apparatus includes forming a metal oxide by oxidizing a metal film adhered to the inside of a processing chamber of the substrate processing apparatus; forming a complex by reacting the metal oxide with β-diketone; and sublimating the complex to be removed. A cleaning gas containing oxygen and β-diketone is supplied into the processing chamber while heating the inside of the processing chamber. A flow rate ratio of oxygen to β-diketone in the cleaning gas is set such that a formation rate of the metal oxide is lower than a formation rate of the complex. |
| US08562749B2 |
Wafer fabrication process
A wafer fabrication process with removal of haze formation from a pellicalized photomask surface is provided. The wafer fabrication process includes pre-print wafer processing, wafer print processing using at least one photomask having a pellicle, photomask clean processing, wafer print processing using the photomask, and post-print wafer processing. The photomask clean processing step includes directing a laser through the pellicle towards an inorganic particle disposed on the photomask to remove the particle from the photomask by thermal decomposition. |
| US08562740B2 |
Apparatus for directional solidification of silicon including a refractory material
The present invention relates to an apparatus and method for purifying silicon using directional solidification. The apparatus can be used more than once for the directional solidification of silicon without failure. The apparatus and method of the present invention can be used to make silicon crystals for use in solar cells. |
| US08562736B2 |
Chemical admixtures for hydraulic cements
This invention relates to a new class of chemical admixtures for hydraulic cement compositions such as pastes, mortars, grouts and concretes. The cement compositions are comprised of ordinary Portland cement, blended cements, or non-Portland cements made with Supplementary Cementitious Materials. The admixtures contain complexes of metals with derivatives of hydroxycarboxylic acids, and improve properties of cement compositions, including setting, hardness, compressive strength, shrinkage, and freeze-thaw resistance. The invention discloses a method for improving the properties of hydraulic cements by adding the disclosed chemical admixtures to cement compositions, and also discloses methods of preparing said admixtures. |
| US08562733B2 |
Aluminium oxide dispersion
Aluminum oxide dispersion, which is stable in a pH range 5 from 5 to 9 and has an aluminum oxide content of at least 40 wt. %, obtainable by dispersing pyrogenically produced aluminum oxide particles in an aqueous phase, wherein one or several at least dibasic hydroxycarboxylic acids present dissolved in the dispersion and at least one salt of a 10 dialkali metal hydrogen phosphate and/or alkali metal dihydrogen phosphate are added to the aqueous phase each mutually independently in a quantity of 0.3−3×10−6 mol/m2 of aluminum oxide specific surface area. |
| US08562727B2 |
Electroless palladium plating solution
Disclosed is an electroless palladium plating solution which can form a plating layer having excellent soldering properties onto electronic components and the like and excellent wire bonding properties. The electroless palladium plating solution comprises a palladium compound, an amine compound, an inorganic sulfur compound and a reducing agent, wherein a combination of hypophosphorous acid or a hypophosphorous acid compound and formic acid or a formic acid compound is used as the reducing agent, and wherein the palladium compound, the amine compound, the inorganic sulfur compound, the hypophosphorous acid compound, and formic acid or the formic acid compound are contained in amounts of 0.001 to 0.1 mole/l, 0.05 to 5 mole/l, 0.01 to 0.1 mole/l, 0.05 to 1.0 mole/l and 0.001 to 0.1 mole/l, respectively. The electroless palladium plating solution is characterized by having excellent soldering properties and excellent wire bonding properties. |
| US08562725B2 |
Oxygen concentrator having structural sieve beds
Embodiments of oxygen concentrators having a sieve bed that includes a vessel filled with a separation medium are disclosed. The sieve bed vessel at least partially supports one chassis component of the oxygen concentrator with respect to another chassis component. of the oxygen concentrator. |
| US08562722B2 |
Structural reinforcements for filter assemblies
A filter assembly is described herein for controlling the air passing therethrough. The filter assembly can include a housing comprising a cavity formed therein. The filter assembly can also include a filter positioned within the cavity and coupled to the housing. Further, the filter assembly can include a reinforcement structure coupled to an end of the housing and adjacent to a top end of the filter. |
| US08562721B2 |
Battery fire prevention device
A battery fire prevention device includes a lithium battery, a container, and a porous material. The container houses the lithium battery and has an outwardly interfacing wall with an aperture which extends therethrough to vent outgassed battery constituents generally away therefrom. The porous material is disposed within the container between the aperture and the battery. The porous material is capable of trapping lithium particulates outgassed from the lithium battery within the container. |
| US08562718B2 |
Method and apparatus for the supply of dry gases
A built in purifier for a cylinder of essentially nitrogen free gas having a low water content is provided with a molecular sieve 3A adsorbent to adsorb water from the gas, the 3A adsorbent having a particularly low adsorption capacity for nitrogen. |
| US08562715B2 |
Production of molybdenum metal powder
The invention relates to a process for producing sinterable molybdenum metal powder in a moving bed, sinterable molybdenum powder and its use. |
| US08562712B2 |
Method and apparatus for the production of metal compounds
The present invention relates to a method and apparatus for the production of titanium alloys and titanium-aluminum inter-metallic compounds and alloys. Starting from a precursor material including titanium subchloride (titanium trichloride or titanium dichloride), the precursor material is reduced by aluminum to produce titanium-aluminum intermetallic complexes or alloys and aluminum chloride which is driven away from the reaction zone so as to favor the forward reaction and the production of the titanium-aluminum compounds. Starting from a precursor material of titanium subchloride avoids the problems associated with starting from titanium metal (which is expensive to produce) or titanium tetrachloride (a reaction very difficult to control), and results in the production of powdered forms of titanium-aluminum compounds with controllable composition. |
| US08562710B2 |
Fertiliser composition
This invention relates to a storage stable fertilizer composition in the form of pellets or granules comprising an organic fertilizer in admixture with a water absorbent polymer. This invention also relates to a process for producing a storage stable fertilizer composition, the process comprising: i) mixing an organic fertilizer and a water absorbent polymer to form a mixture; ii) pelletizing or granulating the mixture; and iii) drying the pellets or granules for a time and under conditions sufficient to form a storage stable fertilizer composition. |
| US08562709B2 |
Low density mist collector pad
A wire mesh mist collector pad having multiple density zones, the zones being arranged other than to provide a constantly increasing density gradient, provides a reduced pressure drop and increased capacity. For example, the pad can include at least three zones with the zones arranged so that the density gradient in the direction of gas flow through the pad varies from low to high to low or from high to low to high. |
| US08562698B2 |
Device for production of synthesis gas with a gasification reactor with a subsequent quenching space
The invention relates to a device for producing a crude gas containing CO or H2 by gasification of an ash-containing fuel with oxygen-containing gas at temperatures above the fusion temperature of the ash in a gasification reactor and with a connected gas cooling chamber and a tapered connecting channel running from one chamber to the other. The aim of the invention is avoiding known problems and reducing the amount of fly ash and the amount of ungasified fuel, wherein a weak eddy is achieved in the inlet to the subsequent apparatuses in order to avoid deposits there with a very compact device, wherein the risk of solidification of the slag in the outlet is also avoided. The aim is achieved, wherein in the tapered connection channel (5) eddy reducing or eliminating wall surfaces (6) running over only a part of the cross-section of the connection channel are provided. |
| US08562697B2 |
Process for hydrolysed reforming of liquous cellulose biomass to produce bio-gasoline
The invention discloses a process for hydrolyzed reforming of the ligneous cellulose biomass to produce bio-gasoline, which directly transfers the hydrolyzed-material liquid obtained from ligneous cellulose biomass through hydrolyzing into aqueous catalytic reforming system, the feed subjects to aqueous catalytic reforming reaction in low-temperature reforming reactor filled with catalyst Ni/SiO2—Al2O3 and in high-temperature reforming reactor filled with catalyst Ni/HZSM-5 in turn, the reactant is condensed and phase-separated: uncondensed bio-gasoline is absorbed by absorption liquid-C6 alkane, condensed liquid is phase-separated through phase-separator, bio-gasoline is obtained in the upper layer of the phase-separator. The invention creates a new process for producing high-quality liquid fuel oil using biomass as feedstock, which can automatically layer and separate, omitting the step of rectifying and purifying product. The feedstock is cheap and broadly available. The product can directly used in the present vehicle-carried engine system, and have prosperous market prospect. |
| US08562694B2 |
Fibre-reactive azo dyes, their preparation and their use
Reactive dyes of the formula (1) wherein B is an aliphatic bridging member, G is a sulfo naphthalene group or a sulfo benzene group of the formula (2a) or a pyridone radical of the formula (2b), R1, R2, R3 and R4 are each independently of the others hydrogen or unsubstituted or substituted C1-C4alkyl, (R5)h denotes h identical or different substituents selected from the group sulfo, C1-C4alkyl and C1-C4alkoxy, R6 is hydrogen, sulfo, halogen, carboxy, C1-C4alkyl, C1-C4alkoxy or a fiber-reactive group Z1 of the formula —SO2—Y (3a), —NH—CO—(CH2)1—SO2—Y (3b), —CONH—(CH2)m—SO2—Y (3c), —NH—CO—CH(Hal)-CH2-Hal (3d) or —NH—CO—C(Hal)=CH2 (3e), R7 is amino, C1-C4alkyl or a fiber-reactive group Z2 of the formula —NH—(CH2)n—SO2—Y (3a), (R8)j denotes j identical or different substituents selected from the group sulfo, C2-C4alkanoylamino, ureido, C1-C4alkyl and C1-C4alkoxy, R9 is hydrogen, C1-C4alkyl or C1-C4alkoxy, R10 is hydrogen or C1-C4alkyl, R11 is hydrogen, cyano, carbamoyl or sulfomethyl, and R12 is hydrogen, C1-C4alkyl, or phenyl which is unsubstituted or substituted by C1-C4alkyl, C1-C4alkoxy, C2-C4alkanoylamino, ureido, halogen or sulfo, X1 and X2 are halogen, Hal is chlorine or bromine, h and j are each independently of the other a number 0, 1 or 2; k is a number 1, 2 or 3; I, m and n are each independently of the other a number 2, 3 or 4, and Y is vinyl or a radical —CH2—CH2—U and U is a group removable under alkaline conditions, with the proviso that the dye of formula (1) contains at least one fiber-reactive group Z1 or Z2 are suitable for dyeing cellulosic or amide-group-containing fiber materials. |
| US08562693B2 |
Method of dyeing and lightening keratin materials in the presence of a reducing agent comprising a fluorescent deisulphide dye
The invention relates to a dyeing composition comprising a fluorescent disulphide dye and to a method of dyeing keratin materials, with a lightening effect, that employs said composition. It likewise relates to new fluorescent disulphide dyes and to their uses in the lightening of keratin materials. This composition allows a particularly persistent lightening effect to be obtained. |
| US08562688B2 |
Knee prosthesis with rotatable post
A knee joint prosthesis for implantation to replace a portion of a knee joint. The knee joint prosthesis includes a tibial tray and a bearing member that engages the tibial tray. The prosthesis also includes an insert with a base that is fixed to the bearing member and an extension portion that extends away from the bearing member and the tibial tray. The extension portion has an axis, and the extension portion includes a threaded portion. The prosthesis further includes a post that is rotatably coupled to the extension portion, and the post is rotatable about the axis of the extension portion relative to the insert. Furthermore, the prosthesis includes a retention member that threadably couples to the threaded portion of the insert to limit movement of the post along the axis away from the bearing member and the tibial tray. |
| US08562687B2 |
Modular spacer device for joints of the human body
Disposable modular spacer device of the articulation of a knee including a tibial element, constrainable to an end of the tibial bone in proximity of the articulation of the knee and including a lower surface and an upper surface provided with a radius of curvature R2, and a femoral element, including an inner surface, constrainable to an end of the femoral bone at the articulation of the knee and an outer convex surface, provided with a radius of curvature R1 and in contact with the upper surface of the tibial element, the tibial element and the femoral element having various dimensions or sizes, the tibial element being configured so as to be coupled with any size of the femoral element to adapt the dimensions of the modular spacer device with the dimensions of the bone ends to which it should be connected. |
| US08562684B2 |
Endplate-preserving spinal implant with an integration plate having a roughened surface topography
An interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, and single vertical aperture, as well as an integration plate having a roughened surface topography on its top surface. |
| US08562679B2 |
Three layer breast prosthesis
A breast prosthesis that includes an outer first layer, a middle second layer and an inner third layer. The outer first layer includes a first material that has a first firmness. The first firmness allows for a 20 mm to a 25 mm penetration by a cone penetrometer. The first layer has a shape corresponding to a shape of a breast form. The middle second layer is disposed adjacent to the first layer and includes a second material that has a second firmness that is greater than the first firmness. The inner third layer is disposed adjacent to the second layer opposite from the first layer and includes a third material that has a third firmness that is less than the second firmness. |
| US08562675B2 |
Extended depth of focus (EDOF) lens to increase pseudo-accommodation by utilizing pupil dynamics
In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm). |
| US08562672B2 |
Apparatus for treatment of cardiac valves and method of its manufacture
A prosthetic valve including a replacement valve having a tubular valve body wall, an expandable stent having a framework with first and second ends, and suturing holding the framework to the valve body at the first and second ends. The suturing at the first end is colored differently from the suturing at the second end. |
| US08562665B2 |
Tubular stent consists of chevron-shape expansion struts and contralaterally attached diagonal-connectors
A circumferentially connected stent in a non-expanded state with a longitudinal axis, includes a first expansion column strut pair having a first expansion strut, a second expansion strut with a joining strut. The first expansion column strut pair defines a chevron shaped slot, and a plurality of the first expansion strut pair forms a first expansion column. A second expansion column strut pair includes a first expansion strut, a second expansion strut and a joining strut. The second expansion column strut pair defines a chevron shaped slot, and a plurality of the second expansion strut pair forms a second expansion column. A first serial connecting strut column is formed of a plurality of first connecting struts, and the first connecting strut column couples the first expansion column to the second expansion column. |
| US08562662B2 |
Devices and methods for treatment of vascular aneurysms
The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm. |
| US08562660B2 |
Methods to regulate polarization and enhance function of excitable cells
Minimally invasive delivery with intercellular and/or intracellular localization of nano- and micro-particle solar cells within and among excitable biological cells to controllably regulate membrane polarization and enhance function of such cells. The cells include retinal and other excitable cells. |
| US08562659B2 |
System and method for administering light therapy
A sleep mask is configured to provide light therapy to a subject. The sleep mask may provide a comfortable delivery mechanism for the light therapy, and may deliver the light therapy to the subject while the subject is asleep, in the process of going to sleep, and/or waking from sleep. In one embodiment, the sleep mask includes one or more of a shield, a strap, a first lighting module, and/or a second lighting module. |
| US08562656B2 |
Retaining mechanism
A retaining mechanism for use in affixing a stratum to bone is disclosed. The retaining mechanism comprises a stratum, a shoulder element and a retaining element. The stratum comprises a first surface, a second surface, and at least one hole extending between the first surface and the second surface, wherein the second surface is configured to engage at least a portion of the bone. The shoulder element is configured to engage the stratum and configured to at least partially overlap the at least one hole. The retaining element is configured to engage the stratum and configured to at least partially overlap the shoulder element such that the shoulder element helps prevent inadvertent backing out of a fastener after the fastener has been fully inserted into the at least one hole. |
| US08562654B2 |
Methods for percutaneously extending an existing spinal construct
Methods and techniques for percutaneously extending an existing spinal construct ipsilaterally with an additional spinal construct in a patient are disclosed. An inline rod connector is utilized which includes an elongate additional rod integrally attached thereto. The additional rod is placed through an access port in a first orientation generally parallel to the longitudinal axis of the access port and rotated to a different second orientation generally transverse to the longitudinal axis of the access port. During such rotation the additional rod is moved subcutaneously beneath the skin of the patient from the existing spinal rod to an additional bone engaging implant. In another arrangement, the extension of an existing spinal construct in a minimally invasive procedure uses a rod connector having an offset support for receiving an additional spinal rod that may be placed laterally interiorly or exteriorly of the existing spinal construct. |
| US08562646B2 |
Anchoring to soft tissue
Soft tissue anchors can be used in various surgical procedures, including pelvic floor reconstruction procedures. The anchors have one position that allows passage through the body and another position that inhibits passage of the anchors back through the soft tissue when a pull-back force is applied to the anchors by an implant, such as a surgical sling used for support of the urethra. |
| US08562645B2 |
Method and apparatus for forming a self-locking adjustable loop
A self-locking adjustable loop construction and a method of forming the construction are disclosed. The construction can include a flexible member having a first end, a second end and a first portion therebetween. The first end can be passed back through the first portion at a first point such that the first end passes through the first portion from a first side of the flexible member to a second opposite side of the flexible member. The first end can be passed through the first portion at a second point spaced apart from the first point such that the first end passes through the first portion from the second side to the first side so as to place the second end outside of the first portion. |
| US08562637B2 |
Temporary vascular filter
The present invention provides a method of deploying a medical filter within a channel in a patient's body and filter systems which can be used in such a method. Such a filter may include a radially expandable body 52 having an opening 56 in a proximal length thereof. In one method, the filter is urged along a length of the channel with the filter body in a radially reduced configuration. This body is expanded to substantially fill the lumen of the vessel and orient the opening in the body proximally. Body fluid is permitted to enter the filter body through the proximally oriented opening and pass distally through the distal length of the body so that the distal length of the body filters from the body fluid particulate material entrained therein. The proximal length of the body can be drawn into the retrieval catheter, thereby effectively closing the proximally oriented opening within the catheter to retain the particulate material within the enclosure. In a preferred embodiment, the filter body 52 is formed of a porous, resilient fabric having pores therein and the proximal opening 56 is at least five times the size of such pores. |
| US08562626B2 |
Devices for harvesting a skin graft
The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister. |
| US08562620B2 |
Bone treatment systems
Systems, bone cements and methods for treating vertebral compression fractures can utilize a bone cement comprising of a mixable liquid monomer component and a non-liquid component including polymer particles, wherein the non-liquid component is configured for controlled exposure to the liquid monomer over a setting interval of the bone cement. In a method of use, liquid and non-liquid components are mixed, and the bone cement is injected into bone wherein a lengthened setting interval is provided in which the mixture is configured for a flowability that prevents unwanted extravasation. |
| US08562617B2 |
Knee ligament balancer
An orthopaedic surgical device comprises a first sensor component and a second sensor component. Each sensor component includes a paddle set to contact a proximal tibia and a distal femur of a patient. The first sensor component and the second sensor component being movable with respect to one another to extend one paddle set beyond the other paddle set, and each paddle set includes cutouts for the clearance of the patellar tendon to avoid the need to evert the patella during use. |
| US08562614B2 |
Disposable cartilage cutter
A medical device that is composed of a sterilizable material, is used to create thin cartilage discs, and includes a device body and a cover with a plurality of holding devices, each of which includes a section that with a recess located in the top side of the device body, the recess being entirely or partially enclosed by a delimiting ridge, and being closable via a projection located on the top side of the cover, and in which the lateral delimiting ridge has a guide slot, into which a cutting blade is inserted and guided via an end face of the section and extends, at a distance that differs for each section, parallel to the bottom surface of the particular recess. It is therefore possible to create thin cartilage discs having certain, different thicknesses and a consistent level of quality, even without using the known shims. |
| US08562613B2 |
Method kit for treating bony defects
The present invention is a kit and a method of using a kit for treating bone including a fill material mixture made of osteoconductive material, osteoinductive material and a lubricating carrier, a porous container to receive the fill material mixture and a tool that flowably introduces the fill material mixture into the porous container. |
| US08562611B2 |
Joint arthroplasty devices and surgical tools
Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty. |
| US08562610B2 |
Compliant device and method for cutting an intervertebral disc
Devices for cutting an intervertebral disc that may include an elongated shape with a distal end and a proximal end and being sized for insertion into an intervertebral space. The devices may include a number of articulating segments that are movably connected together to be shaped in a variety of angular orientations to conform to the shape of the intervertebral disc. The segments may include one or more exposed cutting surfaces that cut the disc as the device is moved through the intervertebral space. |
| US08562604B2 |
Bipolar high frequency treatment device
Provided is a bipolar high frequency treatment device including a catheter tube insertable into a body through a treatment device passage of an endoscope; a first forceps blade and a second forceps blade at the top end of the catheter tube, which first forceps blade and second forceps blade can be opened and closed by operating from outside the body; a support member for supporting the first forceps blade and the second forceps blade so that the blades are able to open and close; and a voltage supplier for supplying a high frequency voltage to the first forceps blade and the second forceps blade, wherein the first forceps blade and the second forceps blade are electrically insulated with an insulating element. |
| US08562599B2 |
Treatment apparatus with frequency controlled treatment depth
An electro-surgical system actively maintains an optimal heating profile at the electrode-patient contact surface under varying load resistivity, thereby reducing the risk of burns and maximizing patient comfort. A set of temperature sensors is integrated within the electrode assembly of the electrosurgical system. The sensors are located both at the center and the edges of the electrode. The sensors are thermally coupled to the electrode-patient contact surface. As RF power is applied, a control loop monitors the temperature at the center and edges of the electrode. If the edge temperature of the electrode is high compared to its center temperature, then the control loop increases the operating frequency, effectively driving heat towards the center of the electrode. Conversely, if the edge temperature of the electrode is low compared to its center temperature, then the control loop decreases the operating frequency, effectively driving heat towards the edges of the electrode. |
| US08562598B2 |
Electrosurgical system
An electrosurgical system can include an electrosurgical generator, a feedback circuit or controller, and an electrosurgical tool. The feedback circuit can provide an electrosurgery endpoint by determining the phase end point of a tissue to be treated. The electrosurgical system can include more than one electrosurgical tool for different electrosurgical operations and can include a variety of user interface features and audio/visual performance indicators. The electrosurgical system can also power conventional bipolar electrosurgical tools and direct current surgical appliances. |
| US08562591B2 |
Drug infusion system and method adapted to start during programming cycle
Drug infusion system capable of delivering a fluid medication to a patient and method for doing same is described. An implantable drug delivery device is capable of delivering the fluid medication at a programmable rate to the patient under control of an original programming cycle having a plurality of steps in a plurality of time slots beginning at a starting time. The programming cycle specifies the programmable rate for each of the plurality of steps. An external controller is capable of storing a program representative of the original programming cycle in the implantable drug delivery device at a programming time. The drug infusion system adjusts the implantable drug delivery device so that the original programming cycle will begin at a time during the original programming cycle adjusted for the programming time. |
| US08562589B2 |
Swallowable drug delivery device and method of delivery
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. |
| US08562587B2 |
CGM-based prevention of hypoglycemia via hypoglycemia risk assessment and smooth reduction of insulin delivery
An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually. |
| US08562581B2 |
Skin friendly diaper
A disposable absorbent article is disclosed having a wide breathable backsheet formed of a single layer of material, preferably in an hourglass configuration, and a narrow containment assembly attached to the backsheet along its longitudinal axis. The placement of the containment assembly creates two regions on either side of the backsheet which form wings which extend laterally beyond the margins of the containment assembly. Fasteners provided on the wings permit attachment of the wings together to form breathable side panels. The fasteners may be configured to engage limited areas of the backsheet and to resist engagement of other areas thereof. The containment assembly comprises a pervious topsheet and an impervious backing film sandwiching an absorbent core. The backing film is generally as narrow as the top sheet, maximizing the breathable area of the absorbent article, and minimizing the use of environmentally persistent plastic films. |
| US08562578B2 |
Drainable pouch
A drainable pouch is disclosed which comprises a pair of sidewalls of flexible sheet material having side edges joined together to define a cavity having a discharge end provided with an outlet valve for draining the cavity. The sidewalls also are joined together throughout a central region thereof such that the cavity formed by the sidewalls completely surrounds the central region. With this construction, the central region defines a peripheral edge and has at least one opening in a location which is spaced inwardly of the peripheral edge to receive and secure the outlet valve when the discharge end has been folded. |
| US08562572B2 |
Disposable, sterile fluid transfer device
The present invention relates to a sterile sample collection device for fluids and a method of using the same. It is comprised of a transfer device having a body with a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to tube which is then connected to a collection bag. The plunger has corresponding first and second ends. The first end of the plunger when in the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. |
| US08562566B2 |
Stent delivery and guidewire guidance system
A system for controlling multiple guidewires comprises a guiderail, which has a housing that defines a first guidewire lumen and a second guidewire lumen. The guidewire lumens extend through the entire length of the guiderail. The guiderail housing further defines a first longitudinal opening that extends from the first guidewire lumen to the exterior of the guiderail, and a second longitudinal opening that extends from the second guidewire lumen to the exterior of the guiderail. |
| US08562562B2 |
Intravenous fluid heater
This invention is directed to a portable intravenous fluid heater that can weight less than 10 oz having an internal power supply internal tubing that is heated by a heating element; a logic assembly; an external power terminal for connecting an external power supply; and computer readable instructions, that when executed by the processor, perform the steps of receiving output temperature from the fluid output heat sensor, removing power from the heating element if the output temperature is above a predetermined temperature to reduce the temperature of fluid exiting the tubing and delivering power to the heating element when the output temperature is below a predetermined temperature. |
| US08562560B2 |
Medical catheter assembly including a balloon bolster
A medical catheter assembly including either a reinforced balloon bolster or the combination of a balloon bolster and a wire-basket bolster. According to one embodiment, the medical catheter assembly is a low-profile replacement PEG device comprising a feeding tube, an external bolster, an end cap and an internal bolster. The internal bolster comprises a first expandable structure and a second expandable structure. In one embodiment, the first expandable structure is a balloon and the second expandable structure comprises reinforcing members. In another embodiment, the first expandable structure is a balloon and the second expandable structure is a wire basket bolster. The feeding tube has a feeding lumen and an inflation lumen, extending parallel longitudinally. The external bolster is fixed to the external end of the feeding tube and has a feeding lumen aligned with that of the tube and an inflation lumen aligned with that of the tube. |
| US08562556B2 |
Nasal rinse tip
A device for nasal lavage is described. The device ejects a gentle flow of fluid under pressure. The fluid stream provides a high quantity of fluid at low pressure. The low pressure fluid stream is more comfortable for a user than a high pressure fluid stream that are delivered by various types of pressurized cans of solution. |
| US08562554B2 |
Side-by-side lacrimal intubation threader device
A device for inserting a flexible silicone intubation stent into the lacrimal drainage system of a patient. The device has an oblong hollow semi-rigid probe having the flexible stent releasably secured to its blunted distal end. The probe and stent are oriented in a side-by-side configuration for endwise insertion into the punctum. The stent can be temporarily secured to the distal end of the probe by engaging the probe's distal opening. The stent can be detached by injecting a pressurized fluid through the channel of the probe thereby forcing the distal end of the stent to pop off. The proximal extremity of the stent is secured in the patient by an integrated or separate punctal anchor. |
| US08562550B2 |
Interior and exterior cast assemblies for repairing a bone fracture and including interior inflatable or mechanically expandable inserts as well as exterior wrap around and adhesively secured braces
A cast for aligning and supporting first and second bone locations adjoining a bone fracture zone including a body employed in at least one of interior and exterior locations of the bone surrounding the fracture zone. The body provides for at least one of aligning the bone locations on either side of the fracture zone and influencing the bone locations in a compressive fashion against the fracture zone during healing of the bone. The body may further include an internally inserted membrane, such as further exhibiting inflatable bladder incorporating a plurality of elongate stiffening members. |
| US08562546B2 |
System and method for evaluating tissue
The present invention provides a sensor system for measuring an elastic modulus and a shear modulus and a method for using the sensor system to evaluate a tissue by determining the presence of and/or characterizing abnormal growths. The method involves applying a set of forces of different magnitudes to one or more locations of tissue, detecting the corresponding displacements due to said applied forces, determining the forces acting on those locations of tissue which are a combination of forces from the applied voltages and the countering forces from tissue deformation, obtaining the elastic modulus and/or shear modulus for a plurality of locations, and determining abnormal growth invasiveness, malignancy or the presence of a tumor from said elastic and/or shear moduli. |
| US08562543B2 |
Medical instrument
A medical instrument includes a housing, a stylet having a portion in the housing, a cannula coaxially receiving the stylet and having a portion in the housing, and a member slidably coupled to the housing. The stylet and the cannula are movable between an extended position and a retracted position. The member is configured with first and second bars to move the stylet and the cannula from their extended positions to their retracted positions. |
| US08562538B2 |
System for determining the left-ventricular ejection time TLVE of a heart of a subject
In order to reliably determine the left-ventricular ejection time TLVE of a heart of a subject, at least two different measuring methods are employed. This includes in any case the derivation of a first waveform related to thoracic electrical bioimpedance or bioadmittance. A second waveform can be determined by using pulse oximetry, Doppler velocimetry, measurement of arterial blood pressure and measurement of peripheral electrical bioimpedance or bioadmittance. Depending on signal quality, the results obtained by each method are weighted and then averaged. The weighted average for left-ventricular ejection time is used as an input variable for cardiovascular monitoring methods, which determine objective measurements of cardiovascular function and performance. Such measurements include, but are not limited to, left ventricular ejection fraction, stroke volume, cardiac output, systolic time ratio, and indices of ventricular contractility. |
| US08562535B2 |
Probe holder
A probe holder having a removable mechanical retention device; a first tube having a longitudinal slot and two opposing notches at each end, the notches configured for engaging the removable mechanical retention device; a second tube having a longitudinal slot and configured for rotational mating with the first tube; a top cap and a bottom cap, each of the top cap and bottom cap being configured for releasably engaging the first tube with the removable mechanical retention device, and for restraining rotation of the first tube when so engaged, while permitting rotation of the second tube relative to the first tube between an open configuration and a closed configuration. |
| US08562529B2 |
Method and system for non-invasive determination of glycogen stores
Provided is a non-transitory machine readable medium on which is stored a computer program for non-invasive determination of glycogen stores including, the computer program including instructions which when executed by a computer system perform the steps of: receiving an ultrasound scan of a target muscle; and evaluating at least a portion of the ultrasound scan to determine glycogen store within the target muscle. |
| US08562527B2 |
General-purpose medical instrumentation
A general-purpose, low-cost system provides comprehensive physiological data collection, with extensive data object oriented programmability and configurability for a variety of medical as well as other analog data collection applications. In a preferred embodiment, programmable input signal acquisition and processing circuits are used so that virtually any analog and/or medical signal can be digitized from a common point of contact to a plurality of sensors. A general-purpose data routing and encapsulation architecture supports input tagging and standardized routing through modern packet switch networks, including the Internet; from one of multiple points of origin or patients, to one or multiple points of data analysis for physician review. The preferred architecture further supports multiple-site data buffering for redundancy and reliability, and real-time data collection, routing, and viewing (or slower than real-time processes when communications infrastructure is slower than the data collection rate). Routing and viewing stations allow for the insertion of automated analysis routines to aid in data encoding, analysis, viewing, and diagnosis. |
| US08562524B2 |
Detecting, assessing and managing a risk of death in epilepsy
A method for determining and responding in real-time to an increased risk of death relating to a patient with epilepsy is provided. The method includes receiving cardiac data and determining a cardiac index based upon the cardiac data. The method includes determining an increased risk of death associated with epilepsy if the indices are extreme, issuing a warning of the increased risk of death and logging information related to the increased risk of death. Also presented is a second method for determining and responding in real-time to an increased risk of death relating to a patient with epilepsy comprising receiving at least one of arousal data, responsiveness data or awareness data and determining an arousal index, a responsiveness index or an awareness index, where the indices are based on arousal data, responsiveness data or awareness data respectively. The second method includes determining an increased risk of death related to epilepsy if indices are extreme values, issuing a warning of the increased risk of death and logging information related to the increased risk of death. A computer readable program storage device is also provided. Also provided is a method for receiving body data, determining a cardiac, an arousal, a responsiveness, or a kinetic index, determining an increased or increasing risk of death over a first time window relating to a patient with epilepsy and issuing a warning and logging relevant information. |
| US08562521B2 |
Surgical access system and related methods
A surgical access system including a tissue distraction assembly and a tissue refraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site. |
| US08562519B2 |
Pumping system and method for assisting a patient's heart
A cannula for a patient includes an elongate body having a length of at least 70 cm and a channel extending through the body defining a wall. The cannula includes a wire embodied within at least a portion of the wall. The body has a proximal end, a distal end having a tip opening through which the channel extends and a plurality of side holes through the wall in proximity to the tip for unimpeded flow of blood at the distal end. The cannula includes a barbed fitting at the proximal end. The cannula includes a suture wing for securing the elongated body to the patient. A system for assisting a patient's heart. A method for assisting a patient's heart. |
| US08562513B2 |
Endoscope device
An endoscope device comprising: an elongated tubular insertion part; a plurality of arm members which is provided in the distal portion of the insertion part so as to protrude forward and is capable of treatment with a treatment tool inserted thereinto; an observation main body provided in the distal portion of the insertion part so as to freely separate from the insertion part; an energization member which energizes the observation main body disposed within the distal portion of the insertion part toward the direction opposite to the plurality of the arm members in the radial direction of the insertion part; and a holding mechanism which resists the energization member to hold the observation main body in a state where the observation main body is disposed within the distal portion of the insertion part and is capable of releasing the holding state. |
| US08562511B2 |
System for inducing a subject to fall to sleep
A system for inducing a subject to fall to sleep includes a light pattern generator for generating a time varying light pattern in view of the subject. Further, the system includes a breathing rate measuring unit for measuring a breathing frequency of the subject. In addition, the system includes a control unit connected to the breathing rate measuring unit and the light pattern generator, for controlling the light pattern generator such that the generated light pattern has a pattern frequency substantially between the measured breathing frequency and a pre-selected desired frequency. |
| US08562510B2 |
Incubator or open patient care unit with automatically actuated side panes
An incubator or open patient care unit (1) is provided, which can be opened and closed by one or more side panes (2). The side pane (2) or each side pane (2) is equipped with essentially vertical guide elements (3, 4). A drive (10) may be provided with an associated analysis unit (11) for the drive (10), wherein the analysis unit (11) receives sensor and/or switching signals, so that the side pane (2) can be automatically opened and/or closed by a preset time or sensor signal. |
| US08562508B2 |
Mobility-enhancing blood pump system
A blood pump system includes a first implantable housing, an implantable blood pump independent from the first implantable housing, and a percutaneous extension. The first implantable housing includes a rechargeable power storage device. The implantable blood pump supplements the pumping function of a heart. The rechargeable power storage device supplies electrical power to the implantable blood pump. The percutaneous extension is coupled to the rechargeable power storage device and adapted to traverse the skin. The percutaneous extension is configured to releasably connect to an external power supply adapted to provide power for recharging or supplementing the rechargeable power storage device to power the implantable blood pump. |
| US08562505B2 |
Uniform field magnetization and targeting of therapeutic formulations
Systems and methods for magnetic targeting of therapeutic particles are provided. Therapeutic particles comprise one or more magnetic or magnetizable materials and at least one therapeutic agent. Therapeutic particles are specifically targeted using uniform magnetic fields capable of magnetizing magnetizable materials, and can be targeted to particular locations in the body, or can be targeted for capture, containment, and removal. Also provided are bioresorbable nanoparticles prepared without the use of organic solvents, and methods for therapeutically using such bioresorbable nanoparticles. |
| US08562503B2 |
Disk package for a centrifuge rotor
The invention refers to a disk package for a centrifuge. The disk package comprises a plurality of separating disks provided on each other in the disk package. Each separating disk extends around an axis of rotation for the centrifuge rotor and has tapering shape with an inner surface and an outer surface along the axis of rotation. Each separating disk has inner edge, defining a central opening of the separating disk, and outer edge. Each separating disk is manufactured of a material. The separating disks comprise a plurality of first separating disks comprising a number of distance members, which extend away from the inner surface and/or outer surface. Each distance member comprises at least one contact zone abutting an outer surface and inner surface, respectively, of an adjacent separating disk in the disk package. The contact zone has a continuously convex shape seen in a cross section. |
| US08562501B2 |
Methods for separating constituents of biologic liquid mixtures
Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma while retaining the platelets and other factors. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants. |
| US08562499B2 |
Apparatus and methods relating to corrugated materials, containers, and packaging
A machine for transitioning a box cutout from a flat configuration to a collapsed box configuration includes a first drive wheel configured to drive a box cutout towards a plunging area; a plunger configured to apply force to a central portion of a bottom panel of the box cutout so as to fold the box about a lateral bisecting axis and propel at least a portion of the box cutout downward; and opposed second and third drive wheels configured to grab a box cutout propelled downward by the plunger and further draw the box cutout downward into a collapsed box configuration within a collection area. A box cutout transitioned to a collapsed box configuration in this manner may include a bottom panel having plurality of unbroken minor score lines and broken major score lines. |
| US08562492B2 |
Exercise apparatus with resilient foot support
An exerciser including a movable body carriage mounted on an exerciser frame for movement along tracks provided by the frame. A resilient foot engaging assembly extends from the exerciser frame. The resilient foot engaging assembly is adapted to be engaged by the user's feet to absorb the energy of movement in a first direction and to provide the user with a bouncing movement, which the user may translate into a movement of the movable body carriage in the opposite direction. The resilient foot engaging assembly may be provided as an attachment and retrofitted to existing exercisers. The resilient foot engaging assembly includes a unit mounting frame assembly and an independent usable exercising unit, such as an inflated dome or trampoline unit, removably secured thereon. The exerciser may include a resilient resistance system coupled to the movable body carriage and a set of pull lines with user grips trained over pulleys carried by the exerciser frame. Also disclosed are methods for enabling users to exercise in either one of two different modes. |
| US08562491B2 |
Seated exercise apparatus
A seated exercise apparatus comprises a frame having a seat attached to the frame. A pair of opposed cranks are rotatably coupled to the frame such that they rotate about a first axis. A medial portion of each of a pair of elongated members is rotatably connected to the frame at a second axis. A first end of each elongated member has a handle and a second end of each elongated member is rotatably connected to a one end of a respective pedal arm. The handles may be adjustable to invert the handles from an upper position to a lower position. The other end of each pedal arm is in turn rotatably connected to a respective crank. Each pedal arm also has a pedal adapted to receive a user's foot. In operation, the apparatus provides the user with coordinated seated exercise of both the arms/hands and legs/feet. |
| US08562489B2 |
Athletic watch
A device for monitoring athletic performance of a user has a wristband configured to be worn by the user. An electronic module is removably attached to the wristband. The electronic module has a controller and a screen and a plurality of user inputs operably associated with the controller. The user inputs include a user input configured to be applied by the user against the screen and in a direction generally normal to the screen. |
| US08562484B1 |
Method and apparatus for starting a turbocharged engine in a hybrid vehicle
A vehicle with a modular hybrid transmission that has a combustion engine including a turbocharger and an e-machine use barometric pressure, road grade, and estimated vehicle mass to develop a turbo lag estimate. If it is determined that undesirable turbo lag is likely, the system opens a disconnect clutch between the engine and the e-machine and the engine is started independently of the e-machine. The e-machine is then used to launch the vehicle while the engine is started. |
| US08562482B2 |
Control device for vehicular drive system
A control device for a vehicular drive system is disclosed as including reverse drive for suppression means operative to preclude output member, such as an output shaft and drive wheels, of an automatic transmission portion from inputting a reverse drive force to a differential portion. This prevents a power transmitting member from rotating in a direction opposite to a rotational direction of the same with a running position being set. This suppresses a first electric-motor rotation speed, determined with an engine rotation speed and a power transmitting member rotation speed based on the relationship on mutually relative rotation speeds in the differential portion, from increasing to a high level. This results in improved durability of a first electric-motor. |
| US08562479B2 |
Tandem axle having two drivable axles and a drivetrain which can be partially disconnected
A tandem axle having two drivable axles, each axle including a differential gearing with a drive input gearwheel, drivable by a shaft, as a differential gearing input and with two drive input semi-axles driving the wheels of the axle using axle shaft wheels. The wheels of the first axle are permanently positively coupled to the drive input gearwheel of the axle. An activatable distributor wheel is seated on a drive input shaft of the drive input gearwheel of the first axle. The distributor wheel meshes with a through drive shaft wheel which is arranged in a rotationally rigid fashion on a through drive shaft. The output of the through drive shaft is coupled to the input-side drive input gearwheel of the second axle by means of intermediate members. Switchable clutches are arranged in the second axle between the axle shaft wheels and their adjacent wheels. |
| US08562476B2 |
Manual transmission using chain and planetary gear set as final drive
A transmission for an engine or motor with a reduced package size and increased efficiency comprising: an input sprocket, an output sprocket, a chain, and a planetary gear set. The output sprocket is drivingly connecting to the input sprocket through the chain. The output sprocket has a hollow center portion that receives the sun gear of the planetary gear set. The planetary gear set also includes at least two planet gears meshed with the sun gear which are mounted to a fixed planet carrier for driving a differential with a ring gear portion. When the input sprocket is rotated in a first direction, the chain drives the output sprocket and the sun gear in the first direction, and the sun gear drives the planet gears to rotate in a second direction, opposite the first direction, driving the ring gear portion and differential in the second direction. |
| US08562473B2 |
Speed reducer incorporating portion structure, incorporating method, and eccentric oscillating type speed reducer
There is provided a speed reducer incorporating portion structure for a plurality of industrial machines in which an eccentric oscillating type speed reducer having an internal gear and an external gear that rotates in an oscillating manner while internally meshing with the internal gear is incorporated. The speed reducer may be incorporated in the plurality of industrial machines, respectively, so that the position of a meshing portion when the external gear is assembled to the internal gear has a specific phase relationship common to the plurality of industrial machines with respect to a specific part of an industrial machine in which the speed reducer is incorporated. |
| US08562464B2 |
Multi-stage continuous variable transmission device in multi-shift parallel connection transmission
The invention is constituted by at least two continuous variable transmission devices in different ranges of speed ratios, wherein a clutching device is installed between the driven pulley of the high shift continuous variable transmission device and the driven pulley of the low shift continuous transmission and an unidirectional transmission device or a torque limiting clutching device is installed between the driven pulley and the output shaft of each shift. |
| US08562463B2 |
Belt type continuously variable transmission
A belt type continuously variable transmission that includes a primary pulley; a secondary pulley; a belt where the primary pulley and the secondary pulley are bound; a positioning hydraulic chamber that presses a primary movable sheave to a primary fixed sheave; a supply-side valve that permits working oil to be supplied from the outside to the positioning hydraulic chamber; and a discharge-side control valve that controls permission or prohibition of discharge of the working oil from the positioning hydraulic chamber to the outside. The discharge-side control valve prohibits discharge of the working oil from the positioning hydraulic chamber to the outside when a position of the primary movable sheave is kept constant in the axial direction with respect to the primary fixed sheave. |
| US08562462B2 |
Racket frame
A racket frame 2 includes a body 4 and a first vibration-damping portion 6 fixed to the body 4. The body 4 includes a head 8, a shaft 12, a pair of throats 10 extending from the head 8 to the shaft 12, and a grip 14 connected to the shaft 12. The body 4 includes a second vibration-damping portion 18, and the material of the second vibration-damping portion 18 is different from the material of the first vibration-damping portion 6. The ratio (R2/R4) of a side pressure rigidity R2 to a throat rigidity R4 is 0.26 or greater, a moment of inertia around an axis at a position of 10 cm from a grip end is less than 300 kg·cm2, and a vibration damping rate in an out-of-plane secondary mode is equal to or greater than 0.70 but equal to or less than 1.0. |
| US08562459B1 |
Golf club head
A golf club (40) having a club head (42) with a face component (60), an aft body (61), and a sound modifying sole and crown design is disclosed herein. The face component, which may be composed of a metal material, (60) has a striking area portion (72) and a return portion (74). The aft-body (61), which may be composed of a non-metal material such as composite or thermoplastic material, is composed of a crown portion (62) and a sole portion (64). The sound modifying design, which may include deep pockets or pillars extending from the sole portion (64) to the crown portion (62), alters the sound of the golf club head (42) when it impacts a golf ball. |
| US08562453B2 |
Golf club
A golf club includes: a shaft case being inserted into a hosel from the upper end side of a hosel hole in a head; an extending member with a lower end side which is screwed into the upper end side of the hosel hole, into which the screw member is screwed; and a pair of attachments which is fit onto the shaft and interposed between an upper end surface of the shaft case and a lower end surface of the screw member and each of which has a half-split cylindrical shape, wherein: the shaft case is fixed to the hosel hole by the screw member pressing the shaft via the attachments; and the shaft case is fixable to the hosel hole by removing the extending member and the attachments and screwing the screw member onto the upper end side of the hosel hole. |
| US08562448B2 |
Joint structure
A joint structure includes a sleeve, a connecting shaft, a plurality of elastic pieces and a cross-limiting stopper. The sleeve defines a receiving shaft hole and a first cross slot communicating with the receiving shaft hole. The connecting shaft is partially assembled and received within the receiving shaft hole of the sleeve, the connecting shaft defines a second cross slot corresponding to the first cross slot. The plurality of elastic pieces is elastically received within a space formed between the sleeve and connecting shaft. The cross-limiting stopper is mounted to and partially received within the second cross slot, and partially received in the first cross slot, to enable the connecting shaft to be radially and adjustably installed within the sleeve and prevent the connecting shaft from rotating relative to the sleeve. |
| US08562447B2 |
Torsional shock absorbing apparatus
A torsional shock absorbing apparatus is constructed to have the outer peripheral portions of first spring seats move along the outer supporting edge portions of the side plate when the hub is twisted with respect to the side plate in the positive rotation side, and to have the outer peripheral portions of second spring seats move along the outer supporting edge portions when the hub is twisted with respect to the side plate in the negative rotation side. The sliding resistance of the first spring seat and the outer supporting edge portions is larger than the sliding resistance of the second spring seat and the outer supporting edge portions. |
| US08562446B2 |
Torsion vibration damping apparatus
A torsion vibration damping apparatus can prevent the strengths of its projection portions from being decreased even if the torsion vibration damping apparatus is made small in size, and can damp torsion vibration caused by a transitional torque when a hub member is rotated in the positive side relatively rotated with respect to a rotation member, thereby making it possible to enhance a damping property of the torsion vibration. The projection amount of a projection portion 40A circumferentially projecting in the positive side from the radially center axis O of the projection portion of a hub flange 40 is formed smaller than the projection amount of the projection 40A circumferentially projecting in the negative side from the radially center axis O of the projection portion. The distance L1 between the positive side surface 40b of the projection portion 40A and the stopper portion 48 is longer than the distance L2 between the negative side surface 40c of the projection portion 40A and the stopper portion 48 when the hub member 31 and the disc members 32, 33 are at their neutral positions. |
| US08562441B1 |
Secure, parallel, and independent script execution
A game server and a client device may perform parallel execution of scripts for a computer-implemented virtual game. When the client device determines that a user of the computer-implemented game has performed an in-game action, the client device may send an update notification to the game server that indicates the in-game action and client-side game state information. Then, the client device may determine an event script to execute based on the user's in-game action, and may execute the event script to present an in-game effect to the user in near real-time. Similarly, the game server may determine a corresponding event script to execute based on the in-game action, and may maintain a secure game state by executing the corresponding script independent of the client device's script execution. |
| US08562434B2 |
Method and system for sharing speech recognition program profiles for an application
An embodiment provides a system and method for sharing between computing devices via a sharing interface, a speech recognition program profile for one or more applications. Another embodiment provides a system and method for sharing between computing devices via an sharing interface, a speech recognition program profile for one or more games. In an embodiment of the invention a personal computer or tablet may comprise a computing device and or a sharing interface. In an embodiment of the invention a cell phone may comprise a computing device and or a sharing interface. In an embodiment of the invention a game play device may be a computing device and or a sharing interface. |
| US08562433B2 |
Illuminating controller having an inertial sensor for communicating with a gaming system
A controller for use in interfacing with a computer game. The controller includes a handle having at least one button, and a spherically shaped object connected to only one end of the handle. The spherically shaped object is defined from a translucent plastic material. Further included as part of the controller is an inertial sensor or accelerometer. The accelerometer may, as defined herein, be part of an inertial sensor. The controller also has an illuminating means defined within the spherically shaped object. A circuit is provided for interpreting input data from the at least one button and the inertial sensor, and is configured for communicating data wirelessly. The circuit is further configured to interface with the illuminating means to trigger illumination of the spherically shaped object to switch from an un-illuminated color to an illuminated color. |
| US08562424B2 |
Gameplay-altering portable wagering media
Portable wagering media may be utilized to alter play of wagering games. |
| US08562419B2 |
Gaming system, device, and method providing a multiple streak game
One embodiment provides a gaming system providing a multiple streak game associated with a base or primary wagering game. The multiple streak game includes a multiple streak having a multiple streak continuation condition and a single streak having a single streak continuation condition. The multiple streak is initially the active streak. If an outcome a play of the base or primary wagering game satisfies the multiple streak continuation condition, the multiple streak remains the active streak and the player may win an award. If the outcome does not satisfy the multiple streak continuation condition but satisfies the single streak continuation condition, the multiple streak ends, the at least one single streak is set as the active streak, and the player may win an award. If the outcome does not satisfy either the multiple streak continuation condition or the at least one single streak continuation condition, the multiple streak game ends. |
| US08562418B2 |
Gaming system with non-cash-based progressive awards
A gaming method includes displaying on a display a progressive award as a cash value and incrementing the progressive award in response to play of one or more processor-controlled wagering games or gaming devices linked to the progressive award. One or more processors are used to convert the cash value of the progressive award to a plurality of non-cash values of respective different game parameters, and, in response to a triggering event, a progressive game is awarded using the non-cash value of one of the game parameters. |
| US08562416B2 |
Gaming device and method having independent reels and multiple ways of winning
A gaming device including a plurality of unisymbol reels which are each selectively activated to generate a symbol at an active symbol position. After a plurality of symbols are generated by the unisymbol reels (wherein the number of generated symbols is based on a wagered on number of ways to win), the gaming device analyzes any associated symbols which are generated in active symbol positions over a requisite number of adjacent reel columns to determine whether the generated symbols form part or all of a winning symbol combination (i.e., a combination of associated or related symbols). The gaming device determines any outcomes associated with any formed winning symbol combinations and provides any determined outcomes to the player, wherein unlike a gaming device with paylines, any outcomes provided to the player are not determined based on the number of paylines which may pass through any displayed winning symbol combinations. |
| US08562411B2 |
Electronic gaming devices
An electron game machine is provided that may be used in association with standard or special type lottery tickets to enhance a lottery players game experience. The machine may be configure for single or plural play options and may be recharged for reuse. Game play data may be entered manually or automatically. Game machines may be manufactured as generic devices and programmed with game specific information as needed. |
| US08562409B1 |
Methods for playing competitive wagering games
A system, method, and computer readable storage to provide a wagering game that awards bettors who correctly predict which of several parties in competition will be the last to successfully meet the requirements of a predetermined sequence of outcomes. Bettors can also wager on the length of the sequence achieved. |
| US08562408B2 |
Gaming machine with buy feature games
A gaming machine including a display, a game controller, and a selector. A player operates the selector to enable the player to place one of a plurality of possible wagers on a play of the game comprising at least a first wager consisting of a base wager, and second and third wagers each consisting of a base wager portion and an additional wager portion. There is no guarantee that the at least one added feature will eventuate in a specific play of the game as a result of the player having staked the additional wager portion. |
| US08562407B2 |
Gaming device having a free spin game
A gaming device including a re-initiation mode wherein the probability of extending the bonus game is increased by fixing the reel or reels displaying a locking symbol on the reel. In the re-initiation mode embodiment, the gaming device re-activates some or all of the reels except the reel displaying the locking symbol for a predetermined number of additional free spins or until the reactivated reels display or indicate a terminating symbol on the reels. The gaming device provides any outcomes associated with indicated symbols or combination of symbols. In one embodiment, if a terminating symbol is displayed on designated reels during one of the additional free spins, the gaming device re-initiates the bonus game. |
| US08562405B2 |
Gaming system and a method of gaming
A gaming system comprising a symbol selector that selects, in a first play round, a first symbol to form a part of a first player hand including a plurality of symbols and a second symbol to form a part of a second player hand including a plurality of symbols, and in each subsequent play round, a replacement symbol for modifying one of the first player hand or second player hand. An outcome generator determines for each play round whether the game is completed or should proceed to a subsequent play round based on a ranking of one of the first player hand and the second player hand being higher than the other of the first player hand and the second player hand for at least two consecutive play rounds. The ranking of the first and second player hands is derived from the symbols of the hands. |
| US08562402B2 |
Game system and game information storage medium used for same
A game system includes a housing to be held by a player. The housing incorporates an XY-axis acceleration sensor to detect an acceleration in a X-axis direction and a Y-axis direction and a Z-axis contact switch to detect an acceleration in a Z-axis direction. The sensor and switch detect at least one of an amount (e.g., tilt amount, movement amount, impact amount or the like) and a direction (e.g., tilt direction, movement direction, impact direction or the like) of a change applied to the housing. A simulation program provides simulation such that a state of a game space is changed related to at least one of the amount and direction of the change applied to the housing. |
| US08562400B2 |
Radiant baffle/collector for roof construction and retrofit
A baffle system that can be used to provide ventilation to attics and roofs at the time of new roof construction or retrofit and further provides for solar thermal energy control and harvesting systems in conjunction or combination with the baffle systems. According to one embodiment, the baffle vents are made from a resilient material and are designed and configured to be flexed into a deformed shape, positioned between adjacent roof rafters and released whereupon the baffle vents become wedged between adjacent roof rafters. The baffle vents can function as radiant barriers by providing the baffle vents with a reflecting coating(s) or reflective surface(s). The baffle vents can function as radiant collectors by positioning solar thermal collectors in the air flow channels defined by the baffle vents and darkening the lower surface of the roof sheeting plane. |
| US08562386B2 |
Mobile skateboard-shaped toy with a flywheel
A mobile skateboard-shaped toy which is propelled by a displaceable flywheel is described. The skateboard-shaped toy comprises a skateboard deck with the flywheel positioned within the skateboard deck. The flywheel is positioned such that the flywheel protrudes beyond a top portion and a bottom portion of the skateboard deck. The flywheel is rotatable within the skateboard deck to change a rotational direction of the flywheel with respect to a major axis of the skateboard deck. Additionally, the flywheel can be repositioned at different ride heights within the skateboard deck. In one aspect, the flywheel is removable from the skateboard deck to allow the flywheel to be easily repositioned within the skateboard deck or replaced with another flywheel. |
| US08562384B2 |
Entertaining nose clasp apparatus
An entertaining nose clasp apparatus is described that includes a nose clasp, an extension and an entertainment device. The nose clasp includes two components and a mechanism for the adjustment of the components. The components connect to the nose of a wearer. The extension includes a first side an opposing second side and side edges. The extension is positionable adjoining the nose. The extension stabilizes the position of the entertainment device relative to the nose of the wearer. The entertaining nose clasp apparatus is constructed for operational use in odorous environments, but can also be used in other environments for entertainment. The entertainment device includes a broad range of decorative two and three dimensional objects. |
| US08562379B2 |
Socket and connector
A socket includes a substantially rectangular columnar socket body made of an insulating material and the socket body including a connection recess portion defined on one surface thereof. Side walls opposed to each other in a transverse direction and lead-out pathways formed in the side walls. The socket further includes a plurality of socket contact members arranged side by side within the connection recess portion along a longitudinal direction. One-end portions of the socket contact members extend through the lead-out pathways and protruding outwards beyond an outer surface of at least one of the side walls of the socket body. The socket body includes a depression portion formed on the side wall through which the socket contact members protrude and the depression portion being formed at least around the socket contact members. |
| US08562378B2 |
Electrical connector assembly with an improved front cover
An electrical connector assembly includes an insulative housing (1) with a trapezoid space (11), a contact module (2) assembled to the insulative housing, a shell (4) enclosing the insulative housing and a front cover (5) enclosing the shell. The shell has a top shell (41) and a bottom shell (42) assembled with each other, and the top shell comprises a base portion (411) and an extension portion (413) extending backwards from the base portion. The front cover includes a main portion (51) and a head portion (52) extending forwards from the main portion, and the head portion is enclosing the base portion, with the main portion enclosing the extension portion of the top shell and the bottom shell. |
| US08562369B2 |
Cable assembly with a new interface
A cable assembly (100), comprises: a metallic case (1) having a receiving room; a terminal module (2) disposed in the receiving room; a plurality of metallic clips (9) assembled to a front end of the terminal module; and a cable (8) extended into the receiving room and electrically connected with the terminal module. |
| US08562366B2 |
Coaxial cable connector having electrical continuity member
A coaxial cable connector comprising a connector body; a post engageable with the connector body, wherein the post includes a flange; a nut, axially rotatable with respect to the post and the connector body, the nut having a first end portion a second end portion, and an internal lip; and a continuity member disposed within the second end portion of the nut and contacting the post and the nut, so that the continuity member extends electrical grounding continuity through the post and the nut is provided. |
| US08562364B2 |
Connecting port
A connecting port is provided, which includes a socket casing and a first connecting pin. The socket casing is disposed on a circuit board. The first connecting pin is made in one piece and includes a fixed end, a free end and a plurality of elastic sheets. The fixed end is fixed in the socket casing. Each of the elastic sheets is integrally connected between the fixed end and the free end. |
| US08562359B2 |
Electrical contact for interconnect member
An electrical contact is provided. The electrical contact includes an integrally-formed body having a mating segment, a mounting segment, and a pair of arms interconnect the mating segment and the mounting segment. The arms extend along helical paths for at least some distance as the arms extend from the mating segment to the mounting segment. |
| US08562358B2 |
Patch panel assembly for use with data networks
A patch panel (100) for use with infrastructure management systems that utilizes a plurality of cables interconnected to end-user devices and work area outlets, and integrated circuits to monitor the status of these end-user devices and outlets includes a pair of circuit boards. A plurality of connective jacks (31) are mounted on the first (36) of the two circuit boards, and are interconnected to other network devices. Wires from the jacks extend to and connect with network devices and the first circuit board has a plurality of first integrated circuits (45) mounted thereon which monitor the status of the network devices connected to the jacks. The second circuit board (49) is spaced apart from the first circuit board and it includes a plurality of second integrated circuits (52) that convey the status information obtained from the network work area outlets on the network to network devices, such as switches and scanners of the network (104). |
| US08562356B2 |
Sport personal coach system
A call center system for coaching a player in judgmental aspects of an athletic sport or for practicing judgmental aspects of the sport includes a call center computer having a display and a memory. The system may also include a camera, a telephone, and a position locator system. Either the pictures stored in the memory or pictures taken with the camera are used to provide coaching or practice. Pictures of a golf course, golf course mapping data, or both are stored in a call center system. GPS data indicating the position of a golf ball on a golf course hole is used to provide either an overhead view of the hole and terrain features, pictures of the course at or near the location of the ball, or both, on a golf professional computer display. |
| US08562355B2 |
System and method for guiding next step adaptive behavior
The system and method of the present invention process clarified emotional response data in order to guide next step adaptive behavior. Emotional responses with predetermined clarified intensities are sorted. The best quality clarified intensity or intensities are then selected as the ‘heart of the matter’, which is then shown to a user to reveal how the user is most uniquely responding to a particular subject or issue. The user is then given guidance on how to respond to the particular subject or issue thereby guiding the user's behavior in response to such subject or issue. |
| US08562353B2 |
Method of representing information
A method of representing information to a person comprising displaying an image viewable by a person, the image comprising visual markers representative of portions of a human body minimally necessary to communicate with the person, the visual markers, when viewed by the person, causing the person to extrapolate the human body, a remainder of the image being visually silent with respect to the person. The method is particularly applicable to represent information so as to be perceivable by a hearing-impaired person (e.g. deaf person) wherein a plurality of images, when displayed, one after another on a display device, represent information perceivable by the hearing-impaired person via sign language. |
| US08562347B2 |
Dental implants
A dental implant has a dental implant fixture with a fitting hole at the oral cavity-side end, and an abutment with a fitting portion at one end which is to be fitted, not to be rotatable, in the fitting hole in the dental implant fixture.The dental implant fixture has at a side of the fitting hole opposite to the oral cavity an internal thread with which external threads formed on a cover screw and healing abutment are to be put into engagement. The abutment has a truncated-conical gum piercing portion with a cross section which is larger in area as it goes away from the fitting portion, and a columnar portion which is not circular in cross section and to which a dental prosthesis fixing device is to be attached. The fitting portion has an internal thread smaller in inside diameter than that in the dental implant fixture. |
| US08562340B2 |
Computer automated development of an orthodontic treatment plan and appliance
A computer is used to create a plan for repositioning an orthodontic patient's teeth. The computer receives an initial digital data set representing the patient's teeth at their initial positions and a final digital data set representing the teeth at their final positions. The computer then uses the data sets to generate treatment paths along which the teeth will move from the initial positions to the final positions. |
| US08562335B2 |
Injection interface device
An interface device between an injection tube and a mold provided with an injection hole, wherein the interface device includes a terminal element for an injection tube, with an end piece inserted into one end of the tube and a sealing ring that slides onto the tube, and a mechanism for holding and clamping the terminal element. The mechanism which is to be screwed into a mounting that is rigidly connected to the mold and is arranged around the injection hole, forms a seal between an injection end of the end piece and a sealing surface of the mold at the injection hole. The dismantlable assembly includes a screw-on socket that has a supporting surface for the sealing ring. |
| US08562313B2 |
Pump assembly
A pump assembly with an electric motor includes a stator having an iron core (16) and windings arranged thereon and being arranged in a stator housing surrounding the electric motor to the outside. The stator housing (6) is formed as a cast component, into which the iron core (16) is cast, and the windings have been deposited on the iron core (16) after the casting of the iron core (16) into the stator housing (6). |
| US08562311B2 |
Compressor improvements
A linear compressor has a hollow piston with crown and sidewall. The piston reciprocates in a cylinder. A piston rod connects the piston to a spring. A connection between the piston rod and the piston transmits axial forces directly to the piston crown. The connection transmits lateral forces to the piston at an axial location away from the piston crown. The connection allows rotational flexibility between the piston and the piston rod transverse to and uniformly around the piston reciprocation axis.Other improvements in or relating to linear compressors are disclosed and claimed. |
| US08562310B1 |
Chlorination system with corrosion minimizing components
A pumping apparatus for pumping a liquid from a source to a target including a motor and pump driven by the motor. Sacrificial zinc components are utilized to minimize corrosion due to chlorine vapors. Measures to ensure that liquid is pumped in only one direction include the use of a full wave rectifier and/or a spacer incorporated with a swivel platform to limits the range of the angle between the motor shaft and the pump piston. To minimize the risk of rupturing the pump, the pump piston includes a relieved portion in fluid communication with a transverse bore of the pump housing when the piston is axially inserted within the pump housing in its full forward position. To prevent overheating and damage to the pump components, the pumping apparatus makes use of a positive temperature coefficient (PTC) resistor interposed between the motor and a current source. |
| US08562305B2 |
Controlled magnetohydrodynamic fluidic networks and stirrers
Provided are magnetohydrodynamic stirrers comprising a conduit or cavity having at least two electrodes disposed in such an orientation that, upon the application of a potential or current across the electrode pair within a magnetic field, secondary flows such as chaotic advection is generated. |
| US08562298B2 |
Vertical-axis wind turbine
A vertical axis wind turbine having a vertical rotating axle and a plurality of blades each attached to an upper portion to the rotating axle and at the bottom portion to a convex base dome attached to and rotable with the vertical axle. Each blade wraps around the vertical axle and has a radial width that increases from its upper portion to its lower portion while supporting an open brow section forming a cup-like space and a wedge-like stiffener section. |
| US08562295B1 |
Three piece bonded thin wall cooled blade
A turbine rotor blade formed from three pieces with a pressure wall side piece and a suction wall side piece bonded to an intermediate piece so that a pressure side cooling circuit can be formed as a separate cooling circuit from a suction side cooling circuit. The intermediate piece has film cooling holes and blade tip cooling holes and trailing edge exit slots formed in it that are enclosed when the outer two pieces are boded to it. |
| US08562292B2 |
Steam turbine singlet interface for margin stage nozzles with pinned or bolted inner ring
A steam turbine singlet nozzle airfoil with integral outer sidewall is engaged with an inner ring and an outer ring in a nozzle assembly. The interface of the outer sidewall with the outer ring may include a plurality of mechanical hooks on one or both of the upstream face and the outer radial face of the outer sidewall that engage with complimentary structures on the outer ring. The outer interface may further include low energy welds along limited distances of one or both of the upstream or downstream interface of the outer sidewall and the outer ring. An inner radial end of the singlet nozzle airfoil is pinned into position and fastened to the inner ring. Without a need for high heat welds, distortion of the airfoil and the steam flow path and the associated rework is eliminated and stage performance is improved. |
| US08562291B2 |
Heat dissipation device and centrifugal fan thereof
An exemplary heat dissipation device includes a centrifugal fan and a fin assembly. The centrifugal fan includes a fan frame and an impeller mounted in the fan frame. The fan frame includes a base plate, a cover plate and a side wall extending between the base plate and the cover plate. An air outlet is defined in the side wall. The fin assembly is arranged at the air outlet. The cover plate defines an air inlet corresponding to the impeller and forms an air blocking portion near the air outlet. The air blocking portion defines a space therein. A total cross-sectional area of the space of the air blocking portion increases from an inner side of the air blocking portion near the impeller to an outer side of the air blocking portion near the fin assembly, so that the airflow generated by the impeller can be prevented from reflowing back to the impeller from the fin assembly. |
| US08562289B2 |
Method and system for a leakage controlled fan housing
A method and system for a fan assembly that includes a fan casing having a longitudinal centerline axis extending from an upstream inlet opening to a downstream outlet opening is provided. The fan assembly also includes a first substantially cylindrical casing segment extending circumferentially about and substantially axially aligned with tips of a plurality of blades extending from a rotor hub, the first casing segment including a first inner diameter that is greater than the rotor diameter, a second casing segment configured to extend axially in a direction opposite a flow of fluid through the fan casing, the second casing segment including a second inner diameter, the second inner diameter less than the first inner diameter and the rotor diameter, and a third casing segment including the first inner diameter along a first circumferential edge, the second inner diameter along a second circumferential edge, and a surface extending therebetween. |
| US08562288B2 |
Fluid flow machine with blade row group
A fluid flow machine has a main flow path in at least one stage, with a rotor arrangement and a stator arrangement, resulting in an increased rotor-stator constriction ratio QRS, which satisfies the following equation: [0.2+(KT−0.45)0.1] |
| US08562287B2 |
Grinder pump
A pump is provided including a cutter plate disposed at a pump inlet including a plurality of holes. Multiple embodiments provide that the pump includes a rotatable cutter blade disposed substantially adjacent to the cutter plate. Embodiments include those wherein the plurality of holes are angled in a direction of rotation of the cutter blade. In some embodiments, the cutter blade has at least one relief hole and at least one cutting edge. Additional embodiments include those wherein a ring extends outward from the pump inlet for channeling material toward the pump inlet in a substantially perpendicular approach with respect to the cutter plate. |
| US08562283B2 |
Fan array fan section in air-handling systems
A fan array fan section in an air-handling system includes a plurality of fan units arranged in a fan array and positioned within an air-handling compartment. One preferred embodiment may include an array controller programmed to operate the plurality of fan units at peak efficiency. The plurality of fan units may be arranged in a true array configuration, a spaced pattern array configuration, a checker board array configuration, rows slightly offset array configuration, columns slightly offset array configuration, or a staggered array configuration. |
| US08562282B2 |
Large capacity wind power generator
A large capacity wind power generator is provided, which includes an outer rotor including an upper partitioning plate having a plurality of spokes formed along a circular circumference of the upper partitioning plate at equal intervals and a side partitioning plate formed on one side surface of the outer rotor, the outer rotor having a lower surface and the other side surface which are open; and a windmill formed inside the outer rotor to be rotated by wind flowing through the outer rotor. The side partitioning plate is formed to have an area that is smaller than a half of the entire circumferential area of the outer rotor, and spaces between the respective spokes are open so as to facilitate an inflow of the wind through the side surface of the outer rotor. |
| US08562278B2 |
Side-discharge chipper body
A side-discharge chipper body to be mounted on vehicle used to pull a tree limb chipper. The side-discharge chipper body includes a forestry box adapted to receive chipped landscape materials from a chipper, a side door pivotally mounted to the forestry box, and a conveyor assembly disposed within the forestry box and adapted to discharge chipped landscape material stored within the forestry box out the side door. The side-discharge chipper body can be mounted to a truck chassis. A chipper can be towed behind the vehicle with the side discharge body to provide a landscape removal system. |
| US08562277B2 |
System and method for automated truck loading
An automatic case loader for loading product in a trailer is disclosed. A mobile base structure provides a support framework for a drive subassembly, conveyance subassembly, an industrial robot, a distance measurement sensor, and a control subassembly. Under the operation of the control subassembly, product advances through a powered transportation path to an industrial robot which places the product within the trailer. The control subassembly coordinates the selective articulated movement of the industrial robot and the activation of the drive subassembly based upon the distance measurement sensor detecting objects within a detection space, dimensions of the trailer provided to the control subassembly, and dimensions of the product provided to the control subassembly. |
| US08562275B2 |
Transfer device and semiconductor processing system
A transfer device 17 in a semiconductor processing system includes first and second actuation mechanisms 9A, 9B having first and second support sections movable on first and second vertical planes, respectively, the latter being parallel with each other. First and second movable blocks 18A, 18B are supported on the first and second support sections so that they may be horizontally moved by the first and second actuation mechanisms. Disposed on the first and second movable blocks are first and second handling mechanism 19A, 19B capable of extension and contraction for handling a processing subject substrate W. A control section 20 controls the operation of the first and second actuation mechanisms so that the first and second movable blocks may not interfere with each other. |
| US08562270B1 |
Loading arrangement including a dam for confining catalyst and other particles on the top tubesheet of a chemical reactor
A dam arrangement is provided for confining catalyst and other particles. The dam can be arranged in a wide variety of configurations. In one embodiment, blocks are provided that are releasably secured to the top tubesheet by means of magnets, and sheets are secured to the blocks to create a dam. In another embodiment, the blocks are releasably secured to the tubesheet by fasteners which project into the tops of some of the tubes and then lock into those tubes. |
| US08562267B2 |
Pushpin retaining device and method of retaining without object puncture
In accordance with at least one exemplary embodiment, a pushpin retaining device is disclosed. An exemplary pushpin retaining device can include a resilient, elongated pin that can have a first end portion for puncturing and a second end portion. A grip foot can be operatively associated with the second end portion of the pin. Alternatively, a cut edge can be on the second end portion of the pin. A method of retaining objects without object puncture can include providing a pushpin retaining device. The method can also include puncturing a support surface with an end of the pin of the pushpin device and pressing a portion of an object against the support surface with the grip foot or cut edge, respectively. |
| US08562265B2 |
Method and apparatus for twist lock manipulation
A manipulation device (5) for either securing a twist-lock to a shipping container or releasing it therefrom or both, the device (5) comprising an engagement element (20) operative to engage and rotate at least a portion of the twist-lock so as to secure the twist-lock in the shipping container or to release it therefrom; a support member (15) disposed above the an engagement element (20), the support member (15) being arranged to receive and support a mid region of the twist-lock while allowing a lower portion of the supported twist-lock to protect below the member to be engagable with the an engagement element (20), said support member (15) being in the form of a plate incorporating at least one aperture allowing the lower portion of the supported twist-lock to protect below the plate; wherein said support member (15) is selectively movable out of alignment with an axis of rotation of the twist-lock. |
| US08562258B2 |
Shielded tamper and method of use for making aggregate columns
A tamper device including a shaft for driving a tamper head, and a shield. A tamper head is attached to the end of the shaft for tamping a lift of aggregate in a cavity formed in a ground surface. A shield attached to the tamper device and spaced a predetermined distance above a top surface of the tamper head, the shield having a predetermined length extending upwardly above the tamper head sufficient to prevent sidewalls of a cavity in soft soil in which the tamper device is used from failing and collapsing into the cavity. Methods of constructing aggregate columns with thicker lifts are also disclosed. |
| US08562257B2 |
System for and method of installing foundation elements in a subsea ground formation
The invention relates to a system for installing or removing foundation elements, such as piles, anchors, and conductors, in a subsea ground formation, comprising an impact weight, an hydraulic circuit in turn comprising an hydraulic cylinder for lifting and/or accelerating the impact weight respectively away from and towards the element, the cylinder comprising a piston connected to the impact weight, and wherein a pump for generating an underpressure in the hydraulic cylinder such as to lift and/or accelerate the impact weight by means of this underpressure. |
| US08562256B2 |
Floating system connected to an underwater line structure and methods of use
There is disclosed a floating system positioned in a body of water having a water bottom, the system comprising a host member floating in the water; an elongated underwater line structure, comprising a top connected to the host; a bottom extending to the seabed and adapted to connect to a flowline lying on the seabed; a first portion of the line structure being shaped concave upward; a second portion of the line structure being shaped concave upward; and a transition segment between being shaped concave downward, the transition segment located between the first portion and the second portion. |
| US08562251B2 |
Liquid containment apparatus with flexible wall supports
A fluid containment apparatus with a floor and a side wall is provided. A wall support is included that supports the side wall and can be moved between an initial supporting position and a collapsed position. The side wall is movable from an initial containment position to a collapsed state to allow access for vehicles or other objects to the floor. The wall support and side wall are subsequently movable back to their initial positions. In some arrangements, the wall support is movable back to the initial supporting position from the collapsed position but is not movable beyond the initial supporting position. Additionally or alternatively, in other embodiments the wall support remains in the collapsed position until a returning force is applied to move the wall support back. |
| US08562238B2 |
Pipe handle holding mechanism
A pipe handle holding structure wherein force for holding a bar handle in a holder is minimized, the holding performance whereby the bar handle is held by the holder is improved, and the bar handle and holder are maintained in an appropriate state even in cases in which the bar handle is frequently attached to and detached from the holder. The pipe handle holding structure comprises a round pipe-shaped bar handle, and a holder for holding an external peripheral surface of the bar handle. The holder has a plurality of concealing parts for concealing the external peripheral surface of the bar handle and elastically deforming the external peripheral surface in a pipe diameter direction. |
| US08562234B2 |
Puff manufacturing method and puff manufactured thereby
Disclosed are a method for manufacturing method a puff and the puff manufactured thereby. The method for manufacturing a puff comprises steps of: a) making a perforated cloth by perforating and cutting a puff cloth using a laser perforation apparatus; b) making a puff base by molding the perforated cloth; c) manufacturing a solid powder which includes a porous material which was inserted into a powder and compressed together with same; d) inserting the solid powder into the puff base; and e) manufacturing a puff by covering by sewing the puff cover onto the puff base. |
| US08562232B2 |
Stick-shaped cosmetic material feeding container
A stick-shaped cosmetic material feeder container having a female screw member with meshing parts, a container rear part having concave groove parts, a clutch spring member disposed on the rear side of the female screw member having meshing parts, a spring part urging the meshing parts frontward, and convex parts entering into the concave groove parts and being movable in the axial direction and not rotatable with respect to the container rear part, a rear part of the clutch spring member beyond the spring part is not movable in the axial direction with respect to the container rear part, and the spring part contracts to cancel the meshing around the axis between the meshing parts when an excessive rotation torque effects on a movable body. |
| US08562231B2 |
Printer with independently supported print unit and lid
A thermal printer in which an upper lid portion and a printing unit can be opened off a main body of the printer by a single operation and the upper lid portion is not closed even when a closing direction force is exerted on the printing unit during ink ribbon replacement. The upper lid portion has a stopper 34 that supports an upper lid portion 30 in a predetermined rotative position relative to a main body 20 and releases support of the upper lid portion 30 when the upper lid portion 30 is closed. A unit stopper 44 supports a printing unit 40 relative to the main body 20 at a smaller rotation angle than the upper lid portion 30 and releases support of the printing unit 40 when the printing unit 40 is closed. A connecting member 35 connects the upper lid portion 30 and the printing unit 40 in a fitted state where the printing unit 40 is fitted to the upper lid portion 30. In a state where the upper lid portion 30 and the printing unit 40 are closed, the upper lid portion 30 and the printing unit 40 are connected by the connecting member 35. |
| US08562225B2 |
Optical ferrule, optical ferrule molding die, manufacturing method of optical ferrule, and ferrule with optical fiber
An optical ferrule that holds an optical fiber, the optical ferrule having an ejector pin mark formed by an ejector pin during molding, the optical ferrule includes a ferrule body, ferrule body having an optical fiber insertion opening to be inserted with the optical fiber, optical fiber hole from which a tip end of the optical fiber is to be exposed, and a lower surface of the ferrule body that is to be a reference plane, lower surface of the ferrule body including a recessed section, ejector pin mark being located on a bottom surface of the recessed section, side surface of the recessed section being formed higher than a molding burr of the ejector pin mark. |
| US08562222B2 |
Hub and spindle assembly
A rotating hub and fixed spindle assembly with first and second fluid dynamic journal bearings and first and second fluid dynamic thrust bearings for a disc drive memory system has a pump seal and a radial ring seal at a first axial terminus for lubricant containment, and a capillary seal and a labyrinth seal at a second axial terminus for lubricant containment and storage. Lubricant fluid pressure differences between first and second seals are minimized through one or more lubricant fluid communicating channels in the hub assembly, in order to minimize lubricant fluid loss through a seal. Lubricant fluid can also be purged of any air bubbles by lubricant fluid circulation through the channel. |
| US08562221B2 |
Spindle motor
Disclosed herein is a spindle motor including: a shaft; a sleeve supporting the shaft; a hub including the shaft coupled to the center of rotation thereof; a sealing member including an operating fluid provided between the shaft and the sleeve and formed to be spaced apart from an outer peripheral surface of the sleeve; an oil sealing part including an oil interface formed between an inner peripheral surface of the sealing member and the outer peripheral surface of the sleeve facing each other, and a sealing surface layer formed on an outer side of the oil interface. The sealing surface layer is formed from an inner side of the oil interface formed in the oil sealing part of a fluid dynamic pressure bearing part toward the outer side thereof, thereby making it possible to improve an oil sealing effect in the oil interface. |
| US08562218B2 |
Fluid dynamic bearing system and a spindle motor having a fluid dynamic bearing system
A fluid dynamic bearing including a bearing bush having a central bearing bore in which a shaft is rotatably supported. Surfaces of the shaft and of the bearing bore that face each other are separated from one another by a bearing gap filled with a bearing fluid. A first radial bearing section and a second radial bearing section are disposed along the bearing gap, between which a separator section is disposed. The width of the bearing gap varies with its axial length. The bearing gap has a first inner width ib1 and a second inner width ib2 in the region of the first and of the second radial bearing section on the sides facing the separator section, a first outer width ab1 and a second outer width ab2 on the sides remote from the separator section. According to the invention, the differences resulting from the inner widths and the outer widths, ib1−ab1 and ib2−ab2, lie in an interval of a−t to a+t, where a is greater than zero and t is greater than a. |
| US08562213B1 |
Ventilated wild game carcass bag
A game bag with enhanced features is herein disclosed, comprising a lower portion of the bag provided with open-screened netting which allows for increased airflow over the carcass thus allowing the carcass to cool in a controlled manner, and an upper portion of the bag provided with sections of hook-and-loop fastener. One section of hook-and-loop fastener is provided in a vertical configuration which allows the bag to open up fully across its upper section. Another section is provided horizontally on a strap arrangement to allow for complete sealing of the bag against the carcass. To properly use the game bag, the game is field dressed and hung from a tree or other suitable support. Next, the bag is brought up from the bottom to completely cover the carcass thus sealing it from dirt, insects and other contaminates. |
| US08562212B1 |
Containment bag for use in a commercial disposal container
A non-self supporting containment bag used in conjunction with a dumpster container. The bag and liner each have a zipper, where the zippers are centered on the bag top, and in use, the bag top is usually inverted to access the interior of the bag. |
| US08562209B2 |
Method to control the work of electronic thermometer by using the position of probe and the apparatus composed of
The invention discloses a method to control the work of electronic thermometer by using the position of probe. The probe incased in a disposable sheath, wherein the pre-heating mechanism in the probe and the control switch is connected with the host of the electronic thermometer by wires; and by using the axial reciprocating motion of the probe to trigger the control switch to initiate the electronic thermometer. When using the invention, we use the movement for the assembling of the sheath to initiate the hearting process and measurement, to ensure that the disposable sheath is assembled on the probe, and then execute the measurement, so as to eliminate the possibility of cross infection completely. The invention also exempts the requirement for the users to the return back of the probe into the cavity after use, and brings convenience for the users: Meanwhile, the equipment structure is simple, and the machinery assembles are few by comparison, which effectively decrease the production cost. |
| US08562208B2 |
Critical temperature indicator
A temperature descending indicator which gives a visual indication when the indicator has been exposed to temperatures below a set threshold temperature includes a container having a translucent portion, a first temperature sensitive gel of a first color which will convert to liquid when it is exposed to temperatures below the set threshold temperature, and a second temperature sensitive gel of a second color which will convert to liquid when it is exposed to temperatures below the set threshold temperature, wherein the second temperature sensitive gel is disposed adjacent the translucent portion in a manner to obscure the visibility of the first temperature sensitive gel. A method of making the indicator includes disposing one color gel over the other. |
| US08562204B2 |
Apparatus for metering and mixing pourable material components
Apparatus for dosed mixing of pourable material components, includes a mixing container, two weighing containers, each of the weighing containers including a closable discharge opening for discharging the weighing container into the mixing container; and a weighing device for weighing the content of the weighing container, and several storage containers for respective material components, each storage container including a feeding device for feeding material from the storage container to an assigned weighing container, and the mixing container is arranged below the weighing containers such that the weighing containers are simultaneously dischargeable through the discharge openings into the mixing container. |
| US08562199B2 |
Lighting device
A lighting device can include an LED and a plate-like lens body including a narrow side surface configured as an elongated rectangular light exiting surface. The LED can face towards the lens body so that light emitted in a wide angle direction is directed to the front surface and the rear surface in the thickness direction and so that light in a narrow angle direction can impinge on the second side surface of the lens body to enter the lens body. The lens body can include a first optical system having a lens portion, a first light incident surface, a first total reflection surface, and a second total reflection surface. A second optical system can include a second light incident surface, a third total reflection surface, and a fourth total reflection surface. An air layer can be provided between the lens portion and the first light incident surface. |
| US08562195B2 |
Fiber optic illumination module with fiber optic coupling
A light-emitting module including a light-emitting device, a multi-mode optical fiber, and a housing accommodating the light-emitting device is disclosed. The optical fiber includes a core and first cladding, and has a covered fiber section including a second cladding and a bare fiber section which has a lens for receiving laser light emitted by a light-emitting end surface of the light-emitting device and is not covered with the second cladding. The housing includes an optical fiber penetration pipe for fixing a portion of the bare fiber section so that the light-emitting end surface and the lens face each other. In the optical fiber penetration pipe, the portion of the bare fiber section is fixed by a resin having a refractive index lower than that of the first cladding. |
| US08562192B2 |
Automotive headlamp apparatus for controlling light distribution pattern
An automotive headlamp apparatus includes headlamp units placed in a vehicle and a control unit which controls the illumination of the headlamp units. The headlamp units form a lower beam distribution pattern and an upper beam distribution pattern, and is configured so that a partial region of the upper beam distribution pattern can be non-illuminated. When the entirety of vehicle existent area of a vehicle-in-front travelling in front of a driver's vehicle is contained within the partial region, the control unit controls the headlamp units in such a manner that the partial region is non-illuminated; when at least a part of the vehicle existent area is contained within a region of the upper beam distribution pattern which is other than the partial region, the control unit controls the headlamp units in such a manner that the upper beam distribution pattern is not formed. |
| US08562188B2 |
Wiring structure of rear combination light
A wiring structure of a rear combination light of a vehicle includes a light-side wire, a vehicle-body-side wire holding portion, a stay, a light-side wire holding portion and a wire coupler. The vehicle-body-side wire holding portion is mounted on a rear surface of the vehicle body to hold an intermediate portion of a vehicle-body-side wire. The light-side wire holding portion is mounted on the stay to hold an intermediate portion of the light-side wire on a distal end portion of the stay. The wire coupler is arranged between the rear surface of the vehicle body and a back surface of the rear combination light. The light-side wire is connected to the vehicle-body-side wire via the wire coupler in a state where the rear combination light is mounted on the rear portion of the vehicle body. |
| US08562187B2 |
Powered base for a lamp
Embodiments of a base for a lamp are shown and described, said base including a base member, having an attachment member adapted to attach a combined adjustable arm and lamp to the base member, wherein said base member has a mass sufficient to support the combined adjustable arm and lamp in all possible orientations; at least one outlet module housed in the base member; and a printed circuit board disposed within the base member, said printed circuit electrically connected to a household power outlet, said printed circuit board adapted to electrically connect the at least one outlet module to the household power supply, and wherein said printed circuit board includes a transformer adapted to transform the household power supply into an output power suitable for powering the lamp, and wherein the transformer is electrically connected to the lamp. |
| US08562184B2 |
LED work light
An LED work light has multichip LEDs and a diffusing dome. Each LED may have separate electrical terminals for each chip. The LED work light may have convex lenses forward of each LED. Convex lenses may be hemispherical. Convex lenses may have a nonhemispheric curved surface whose cross section has at least one circular arc and no non-circular arcs. The LED work light has a battery or receives power from an external power source. The LED work light may have a transparent plastic tube as a structural member. A replaceable plastic cover may be added to protect any structural tube or other major transparent part of the LED work light from abrasions. The plastic cover may be tubular. The plastic cover may comprise laminations of plastic that can be removed individually after being abraded. Any external power source may be a wall transformer type and may have current limiting means. The LEDs may be attached to the rear surface of an LED PCB that is fastened to a heatsink in a manner achieving thermal contact between the rear surfaces of the LEDs and the heatsink. A position sensing switch may be used. |
| US08562183B2 |
Actuating assembly for stage light fitting beam processing members, and stage light fitting comprising such an assembly
An actuating assembly for beam processing members of a stage light fitting for generating a light beam has a frame; at least a first and second beam processing member; a motor with a shaft; and transmission means for transmitting motion to the first and second beam processing member, and which connect the shaft of the motor to the first and second beam processing member to selectively move the first and second beam processing member successively between a first position of non-interference with the beam, and a second position of interference with the beam. |
| US08562181B2 |
Light emitting diode bulb
A light emitting diode bulb comprises a heat sink, an insulator cover, a light emitting device package, a plurality of conductive terminals, a driving circuit, a holder, a metal screw thread, and an electrode. The light emitting device package, disposed between the insulator cover and heat sink, is covered by the insulator cover which exposes a portion of the light emitting device package. The conductive terminals are connected with the insulator cover and extend outwardly to be connected with the light emitting device package. The driving circuit converts an AC signal into a DC signal and includes upper conductive rods and lower conductive rods. The conductive rods are connected with the conductive terminals. The holder is connected with the metal screw thread and heat sink. The metal screw thread is connected electrically to one of the lower conductive rods. The electrode is connected electrically to the other lower conductive rods. |
| US08562179B2 |
Lamp with fan and heat sink inside
A fan comprises a housing, a fan, a heat sink, and a light emitting element. The housing has a compartment and forms an opening. The fan is mounted inside the compartment of the housing and has a frame and an impeller mounted inside the frame. A first air-guiding channel is formed between a peripheral surface of the frame and an inner peripheral surface of the housing. The heat sink is coupled to the fan and has a first surface and a second surface, with the first surface facing the impeller. Also, a second air-guiding channel is formed between an outer periphery of the heat sink and an inner surface of the frame. The light-emitting element is disposed on the second surface of the heat sink. In such arrangement, used components and structural complexity of the lamp can be significantly reduced so as to be convenient in assemblage. |
| US08562176B2 |
Light diode with cooling body
A light diode with a lighting body and connecting wires for operating a light diode are disclosed. The lighting body is connected with a separate cooling body associated to the light diode, wherein the light diode is maintained on the circuit board by means of a clamping mechanism. |
| US08562174B2 |
Lamp assembly and method for making
A lamp assembly, comprising a lens, a lamp housing in the form of an integral metal part, the lamp housing cooperating with the lens to at least partially define a lamp chamber that is generally fluidly isolated from an ambient atmosphere outside the lamp chamber, and at least one lamp provided in the lamp chamber and carried by the lamp housing. The lamp housing itself defines a heat sink exposed to the ambient atmosphere outside the lamp chamber such that heat from the at least one lamp is transmitted to the ambient atmosphere. |
| US08562172B2 |
LED tube end-cap having a switch
An end cap for a light-emitting-diode (LED) light tube includes an end cap housing having an end surface, an electric circuit and a switch for closing the electric circuit or opening the electric circuit. The switch includes a switch body having a pivot axis. The switch body is configured to pivotally move, with respect to the pivot axis, between an on-position for closing the electric circuit and an off-position for opening the electric circuit. When the switch is in the off-position, an end part of the switch body protrudes from the end surface of the end cap housing, and when the switch is in the on-position, the switch body and is substantially flush with respect to the end surface. When the switch is in the off-position, an outer surface of the switch body inclines with respect to the end surface of the end cap housing. |
| US08562171B2 |
LED linear light source and reading apparatus
An LED linear light source includes an approximately rod-shaped light guiding member, at an end portion of which an LED is provided. The light guiding member is in an approximately arc shape in a cross sectional view taken perpendicular to an optical axis. The light guiding member has an upper face including a light emission face for emitting light and a lower face including a reflective face, which are arranged in parallel. A diffusing member diffuses light provided on part of an outer circumferential face adjacent to a light entering end face of the light guiding member. A light absorption member is provided in an outside of the light guiding member near at an end portion thereof. |
| US08562170B2 |
Light emitter to be attached to caps
Disclosed is a light emitter to be attached to caps. The light emitter includes a case having a plurality of second lamps (22) formed at a front surface thereof, a power switch attached to an outer surface of the case, a battery installed inside the case to provide power, a guide groove formed at a center of the case, a mounting clip formed at the outer surface of the case, a sub-body having a lamp at a front surface thereof and being coupled to the guide groove, and switch unit for controlling on/off operation of the lamp. The user freely adjusts the distance of radiant light, amount of radiant light and radiation angle of the lamp. The light emitter is fixed to a pocket to radiate light in the forward direction by arranging the sub-body at a right angle with respect to a case. |
| US08562169B2 |
Heat dissipating chassis for handheld battery operated device
A heat sink for a handheld device is found as a one piece chassis for supporting heat-producing circuits inside the device while having heat radiating surfaces outside the device. In another embodiment a battery pack control circuit under microprocessor control allows battery packs having different battery chemistries and characteristics to be interchanged in the same device without switches or adapters. Control of operating modes of the device despite changes in the battery pack including battery chemistry, state of charge, available voltage, or desired operating mode are automatic. The microprocessor measures the battery pack characteristics, using look up tables in a suitable program to adjust the circuit operating modes. The microprocessor also responds to sequential switch contact closures in setting operating modes. |
| US08562168B2 |
Perimeter lighting fixture with wall trim piece
A perimeter lighting fixture has housing and a separate trim piece. The trim piece is attached to a wall. A wall compound, such as plaster, is smoothed over a blend area or band on the wall just below the trim piece, and also onto a transition section of the trim piece. The housing and/or a reflector of the perimeter lighting fixture is positioned in contact with the trim piece. The trim piece compensates for waviness or uneven wall surfaces. As the trim piece is straight, the variances in wall straightness are corrected. This allows the lighting fixture to be placed against or closely adjacent to the wall, without creating unsightly dark gaps between them, and without highlighting the imperfections in the wall. |
| US08562165B2 |
Pressure activated lighted glove
Exemplary embodiments comprise a lighted glove with an infra red light source which can be activated by applying a force to a pressure sensor that is in electrical communication with the light source. Exemplary embodiments are useful in night vision applications. |
| US08562164B2 |
Edge-type backlight module
An edge-type backlight module includes a back bezel, a light guide plate (LGP), a light source, and a frame. The back bezel includes a supporting portion that has a light source supporting surface and an LGP supporting surface. A horizontal level of the light source supporting surface is lower than that of the LGP supporting surface. The LGP is configured on the LGP supporting surface and has a light-incident side surface and a top light-emitting surface. The light source is configured on the light source supporting surface to provide a light beam. The frame is configured on the back bezel and leans against the LGP. The frame has a reflective surface located on a transmission path of the light beam to reflect the light beam, and the reflected light beam enters the LGP from the light-incident side surface. |
| US08562161B2 |
LED based pedestal-type lighting structure
LED based lamps and bulbs are disclosed that comprise a pedestal having a plurality of LEDs, wherein the pedestal at least partially comprises a thermally conductive material. A heat sink structure is included with the pedestal thermally coupled to the heat sink structure. A remote phosphor is arranged in relation to the LEDs so that at least some light from the LEDs passes through the remote phosphor and is converted to a different wavelength of light. Some lamp or bulb embodiments can emit a white light combination of light from the LEDs and the remote phosphor. These can include LEDs emitting blue light with the remote phosphor having a material that absorbs blue light and emits yellow or green light. A diffuser can be included to diffuse the emitting light into the desired pattern, such as omnidirectional. |
| US08562160B1 |
Chemiluminescent application system
An apparatus for dispensing chemiluminescent or fluorescent material where the material(s) for the production of the chemiluminescent or fluorescent material are housed in separate compartments and mix when they exit those compartments. Also disclosed is a method of illumination by dispensing materials housed in an apparatus where the materials do not mix until they exit that apparatus. |
| US08562153B2 |
Laser scanning display and beam alignment method thereof
A laser scanning display including a micro scanning mirror, and a beam alignment method thereof are disclosed. A scanning display includes a frame, at least one light source fixedly secured to the frame, a lens positioned in front of a light emission surface of the light source, the lens having a holder detachably mounted to an external adjusting device which is to make fine adjustment to finish beam alignment, and a fastening portion for fastening the lens having beam alignment finished thus to the frame. |
| US08562151B2 |
Display device comprising rotating projectors with multiple mirrors and panels
A display device includes a projector assembly, an actuator, a panel element, and a number of mirrors. The projector assembly projects lights of an image. The actuator rotates the projector assembly about a rotating axis. The panel element includes a number of panel surfaces. The panel surfaces adjoin one another in sequence along the rotating axis. The mirrors are arranged in sequence along the rotating axis. The mirrors are oriented toward the respective panel surfaces for adjusting transmission directions of the lights to project the image onto the respective panel surfaces. |
| US08562150B2 |
Optical axis adjustment device, method for adjusting optical axis and projection-type display apparatus
A projection type display apparatus in which an inclination and a positional deviation of optical axes among a plurality of light sources can be easily corrected to obtain a high quality projection image. Green, blue and red laser beams emitted from light sources are converted into collimated beams by condenser lenses, and the positions and angles of the optical axes of the beams of the three colors are evaluated by position detection imaging device and angle detection imaging device, respectively. The positions and angles of the light sources are adjusted by respective actuators so that the positions and angles of the optical axes match each other. Consequently, the laser beams emitted from the light sources can be combined with high accuracy to thereby realize a high definition projection type display apparatus. |
| US08562148B2 |
Control device and electronic device
A control device that controls a video signal to be input to a display device and controls the luminance of a light source that causes light to be incident on the display device includes: a light source luminance control section that controls the luminance of the light source by means of a light source luminance control signal; a storage section that stores relationships between light source luminance control signals and video correction amounts; a video correction signal generating section that generates, on the basis of the video correction amount that is stored in the storage section and corresponds to the generated light source luminance control signal, a video correction signal that is used to correct the video signal; and a video signal correcting section that corrects the video signal by means of the video correction signal. |
| US08562147B2 |
Remote-controlled projector with obstacle detecting capability
A projector including a lens, an IR emission circuit, an IR reception circuit and a central processing circuit is provided. The projector is controlled by a first infrared ray (IR) signal provided by a remote controller. The IR emission circuit emits a second IR signal to detect whether an obstacle is positioned on an optical path of the projection light. When an obstacle is positioned on the optical path, the second IR signal is reflected to the IR reception circuit via the obstacle. The IR reception circuit provides a first and a second output signal in response to the first and the second IR signal respectively. The central processing circuit determines that an obstacle is positioned on the optical path and accordingly alters an operational mode of the projector in response to the second output signal and controls the operation of the projector in response to the first output signal. |
| US08562145B2 |
Display system and method for projection onto non-planar surfaces
A system for projecting changeable electronic content, such as video or digital still images, onto a curved surface. The system includes a housing, a reflector within the housing, and a projector. The housing has an exterior surface and an interior space. At least a portion of the exterior surface is a curved display surface capable of displaying electronic content projected upon it, and at least one portion of the exterior surface has an aperture through the exterior surface to the interior space. The projector is located proximate the aperture for projecting content through the aperture to the reflector. When the projector receives converted content and projects the converted content through the aperture to the reflector, the curved display surface displays the converted content undistorted to a viewer. The system can also provide for display of branded content on a product container having a shape corresponding with the brand. |
| US08562144B2 |
Image projection device and method for controlling air-filter
An image projection device includes a replaceable air filter placed near an opening of a housing, a switcher for switching step by step a working area of the air filter, an air-speed meter for detecting a pollution level of the air filter, and a controller for controlling the switcher. When the air-speed meter detects that the pollution level of the air filter reaches a given threshold, the controller prompts the switcher to switch the working area of the air filter, and then detects a pollution level of the air filter after the switchover for determining whether or not the working area before the switchover needs to be switched. |
| US08562143B2 |
Projection display device with cooling unit
A projection display device that modulates light on the basis of image information to form an optical image, and that projects the formed optical image, includes: light source devices 10R, 10G and 10B; optical modulation device 50 that modulates lights emitted from light source devices 10R, 10G and 10B; and common metal plate 70 on which light source devices 10R, 10G and 10B and optical modulation device 50 are mounted, light source devices 10R, 10G and 10B and optical modulation device 50 being thermally connected via metal plate 70. |
| US08562139B2 |
Image display apparatus
An image display apparatus includes: a light source emitting light; a spatial light modulator having a display region, and modulating the light emitted from the light source in accordance with an image signal; a projection device projecting the light modulated by the spatial light modulator onto a projection surface including an illumination region; and a deflecting section deflecting the light that is emitted from the light source and is then incident on the spatial light modulator. In this structure, the light emitted from the light source illuminates a part of the display region of the spatial light modulator, the light is deflected by the deflecting section, and the illumination region illuminated by the light moves on the projection surface. |
| US08562136B2 |
Visual display with illuminators for gaze tracking
A visual display characterized by hidden reference illuminators is adapted to emit invisible light for generating corneo-scleral reflections on an eye watching a screen surface of the display. The tracking of such reflections and the pupil center provides input for gaze tracking. A method for equipping and an LCD with a reference illuminator are also provided. A system and method for determining a gaze point of an eye watching a visual display comprising reference illuminators are further provided. The determination of the gaze point may be based on an ellipsoidal cornea model. |
| US08562134B2 |
Vision shift amount measuring method and vision shift amount measuring jig
A vision shift amount measuring method includes: forming a reference mark indicating a distance eye point on a surface of a spectacle lens attached to a spectacle frame practically worn by a wearer, and forming a plurality of opaque lines in an area expected to contain a shifted vision on the surface of the spectacle lens with a predetermined space between the adjoining lines; and allowing the wearer wearing the spectacle frame to select the line closest to a position through which the vision passes from the plural formed lines. |
| US08562133B2 |
Simulator for use in ophthalmological measurements
A simulator to be used in ophthalmological measurements includes a display apparatus and a control device. The control device is adapted to control the display apparatus in such a manner that the display apparatus displays an image that is adapted to simulate the arrangement of a pupillary midpoint relative to a reference structure. |
| US08562132B2 |
Photometry device
In a photometry device, photopic vision luminance Lp is measured by a first luminance measuring unit including a first light filter 4 and a first photoelectric converter 5, and scotopic vision luminance Ls is measured by a second luminance measuring unit including a second light filter 6 and a second photoelectric converter 7. A calculation part 8 calculates mesopic vision luminance Lmes based on a measurement value (photopic vision luminance Lp) of the first luminance measuring unit and a ratio of a measurement value (scotopic vision luminance Ls) of the second luminance measuring unit to the measurement value (photopic vision luminance Lp) of the first luminance measuring unit. Consequently, the photometry device can improve measurement accuracy of the brightness (mesopic vision luminance) in mesopic vision. |
| US08562122B2 |
Ink jet inks having improved corrosion resistance for use in ink jet print heads comprising nickel or nickel alloys
The present disclosure pertains to an aqueous ink jet ink having improved corrosion resistance for use in an ink jet print head including: (a) a colorant; (b) an aqueous vehicle; and (c) a certain random hydrophilic polymer additive, wherein the random hydrophilic polymer additive includes a random copolymer consisting of a hydrophilic component and an optional hydrophobic component, wherein the hydrophobic component includes a monomer selected from the group consisting of methyl acrylate and/or vinyl acetate and/or a hydrophobic monomer having a carbon to oxygen ratio of at least about 2.5, and wherein the hydrophobic component has a concentration of less than about 40% by weight, based on the weight of the polymer additive, and the hydrophilic component includes at least one non-acidic hydrophilic monomer having a carbon to oxygen ratio of less than about 2.5, and a monomer with an ionizable acidic group with a carbon to oxygen ratio of less than about 2.5 present in the amount of at least 10%, based on the weight of the polymer additive; and wherein the ink jet print head includes an ink flow passage, at least a portion of which is formed of nickel-containing metal such as nickel or nickel alloy. |
| US08562115B2 |
Condensation control in an inkjet printing system
Inkjet printing systems are provided. One inkjet printing system has a plurality of inkjet printheads, each having nozzles for jetting ink droplets having a vaporizable carrier fluid, a support structure to which the plurality of inkjet printheads are mounted, such that a face of each of the printheads of the plurality of printheads is positioned to jet the ink droplets toward a target area through which a receiver transport system moves a receiver during printing; and a shield between the support structure and the target area creating a first region between the shield and the target area with the shield having at least one opening through the shield through which the nozzles of the printhead can jet the ink droplets to the target area. An energy source supplies energy to cause the temperature of the shield to rise above a condensation temperature of vaporized carrier fluid in the second region. |
| US08562114B2 |
Inkjet ejector having an improved filter
A manifold assembly has been constructed that filters ink before the ink enters an inkjet ejector in an inkjet print head. The manifold assembly includes an adhesive layer having openings, an ink manifold layer having a plurality of openings, the openings in the adhesive layer being aligned with the openings in the ink manifold layer, and a polymer layer having a plurality of filter areas, the filter areas being aligned with the openings in the ink manifold layer and the openings in the adhesive layer, the adhesive layer being interposed between the polymer layer and the ink manifold layer. |
| US08562112B2 |
Piezoelectric actuator, method of driving same, liquid ejection apparatus and piezoelectric ultrasonic osicllator
A method of driving a piezoelectric actuator including: a piezoelectric element containing a piezoelectric body having coercive field points on a negative field side and a positive field side respectively and having asymmetrical bipolar polarization—electric field hysteresis characteristics in which an absolute value of a coercive electric field on the negative field side and a coercive electric field value on the positive field side are mutually different, and a pair of electrodes for applying voltage to the piezoelectric body; and a diaphragm which externally transmits, as displacement, distortion produced in the piezoelectric body when the voltage is applied to the piezoelectric body, includes the step of driving the piezoelectric actuator between a positive drive voltage and a negative drive voltage in a range not exceeding the coercive electric field, from among the positive and negative coercive electric fields, which has the larger absolute value. |
| US08562109B2 |
Liquid ejection head
A liquid ejection head includes a recording element substrate having a member with a liquid ejection orifice, and a substrate having an energy-generating element for ejecting the liquid; a wiring substrate including wirings connected to terminals that are formed along an end portion side of a surface of the substrate where the element is formed and are electrically connected to the element; and a support member including a support supporting the recording element substrate through adhesive, a groove formed along the support and a wiring support supporting the wiring substrate. A sealing material is applied to a connection portion between the terminals and wirings and is applied to a bottom surface of the groove formed on an end portion side of the surface where no terminal is formed. A part of a side of the substrate corresponding to the end portion side is exposed without being covered with the sealing material. |
| US08562102B2 |
Inkjet recording apparatus
An inkjet recording apparatus is provided, which includes a plurality of recording heads, a cap unit, waste ink container and communicating member. Each recording head includes a nozzle face with inkjet nozzles. The cap unit includes a plurality of first ink receiving members and a second ink receiving member. Each first ink receiving member is disposed below and corresponding to each recording head and has a first receiving portion receiving ink discharged from the inkjet nozzles and a first discharging hole discharging the received ink. The second ink receiving member is disposed below and corresponding to the first ink receiving members and has a second receiving portion that collectively receives the ink discharged through a plurality of first discharging holes and a second discharging hole. The communicating member connects the second discharging hole with an ink storage chamber of the waste ink container. |
| US08562100B2 |
Systems and methods for communication of date information between an ink tank and a printing device
Some or all of the needs above can be addressed by embodiments of the invention. According to one embodiment of the invention, a method for determining ink evaporation from at least one ink tank can be provided. The method can include determining a removal time associated with removal of at least one ink tank from a printing device. The method can also include determining an insertion time associated with insertion of the at least one ink tank into a printing device. In addition, the method can include estimating an amount of ink evaporation from the at least one ink tank during the time between the removal time and insertion time based at least in part on the difference between the removal time and insertion time. |
| US08562097B2 |
Transport apparatus for flat materials to be printed with aligned support bar system
A transport apparatus for flat materials to be printed includes a transport belt guided over a plurality of rollers along a centrally indented oval curve and supported on a supporting plate disposed above a supporting region of a roller carrier between a shaped partial plate and a bearing plate. A supporting surface area of the supporting plate is greater than a surface area of a printing window, and the transport belt has a width in the y-direction of a Cartesian coordinate system being wider than a width of the printing window. The indented section of the oval curve is configured at least partially for receiving a printing module or the bottom of at least one ink cartridge having a print head. |