Document | Document Title |
---|---|
US08564025B2 |
Nanowire FET having induced radial strain
An intermediate process device is provided and includes a nanowire connecting first and second silicon-on-insulator (SOI) pads, a gate including a gate conductor surrounding the nanowire and poly-Si surrounding the gate conductor and silicide forming metal disposed to react with the poly-Si to form a fully silicided (FUSI) material to induce radial strain in the nanowire. |
US08564016B2 |
Vertical topology light emitting device
A vertical topology light emitting device comprises a conductive adhesion structure having a first surface and a second surface; a conductive support structure on the first surface; a reflective structure on the second surface, the reflective structure also serving as a first electrode; a semiconductor structure on the reflective structure; and a second electrode on the semiconductor structure. |
US08564014B2 |
Ultraviolet light emitting AlGaN composition and ultraviolet light emitting device containing same
An AlGaN composition is provided comprising a group III-Nitride active region layer, for use in an active region of a UV light emitting device, wherein light-generation occurs through radiative recombination of carriers in nanometer scale size, compositionally inhomogeneous regions having band-gap energy less than the surrounding material. Further, a semiconductor UV light emitting device having an active region layer comprised of the AlGaN composition above is provided, as well as a method of producing the AlGaN composition and semiconductor UV light emitting device, involving molecular beam epitaxy. |
US08564013B2 |
Light-emitting thyristor, light source head, and image forming apparatus
A light-emitting thyristor includes a substrate, a first semiconductor multi-layered mirror of a first conductivity type that is formed on the substrate, a gate layer that is formed on the first semiconductor multi-layered mirror by stacking a plurality of semiconductor light-emitting layers having different peak values of an emission wavelength, and a second semiconductor multi-layered mirror of a second conductivity type that is formed on the gate layer. |
US08564012B2 |
Optoelectronic apparatuses and methods for manufacturing optoelectronic apparatuses
A method for manufacturing an optoelectronic apparatus includes attaching bottom surfaces of first and second packaged optoelectronic semiconductor devices (POSDs) to a carrier substrate (e.g., a tape) so that there is a space between the first and second POSDs. An opaque molding compound is molded around portions of the first and second POSDs attached to the carrier substrate, so that peripheral surfaces of the first POSD and the second POSD are surrounded by the opaque molding compound, the space between the first and second POSDs is filled with the opaque molding compound, and the first and second POSDs are attached to one another by the opaque molding compound. The carrier substrate is thereafter removed so that electrical contacts on the bottom surfaces of the first and second POSDs are exposed. A window for each of the POSDs is formed during the molding process or thereafter. |
US08564010B2 |
Distributed current blocking structures for light emitting diodes
An LED device includes a strip-shaped electrode, a strip-shaped current blocking structure and a plurality of distributed current blocking structures. The current blocking structures are formed of an insulating material such as silicon dioxide. The strip-shaped current blocking structure is located directly underneath the strip-shaped electrode. The plurality of current blocking structures may be disc shaped portions disposed in rows adjacent the strip-shaped current blocking structure. Distribution of the current blocking structures is such that current is prevented from concentrating in regions immediately adjacent the electrode, thereby facilitating uniform current flow into the active layer and facilitating uniform light generation in areas not underneath the electrode. In another aspect, current blocking structures are created by damaging regions of a p-GaN layer to form resistive regions. In yet another aspect, current blocking structures are created by etching away highly doped contact regions to form regions of resistive contact between conductive layers. |
US08564007B2 |
Semiconductor component comprising an optically active layer, arrangement comprising a multiplicity of optically active layers and method for producing a semiconductor component
A semiconductor component comprising an optically active layer and characterized by at least one cooling element and at least one coupling element. Also disclosed is an arrangement comprising a multiplicity of optically active layers and a method for producing a semiconductor component. |
US08564006B2 |
Nitride semiconductor device and nitride semiconductor layer growth substrate
According to one embodiment, a nitride semiconductor device includes a substrate and a semiconductor functional layer. The substrate is a single crystal. The semiconductor functional layer is provided on a major surface of the substrate and includes a nitride semiconductor. The substrate includes a plurality of structural bodies disposed in the major surface. Each of the plurality of structural bodies is a protrusion provided on the major surface or a recess provided on the major surface. An absolute value of an angle between a nearest direction of an arrangement of the plurality of structural bodies and a nearest direction of a crystal lattice of the substrate in a plane parallel to the major surface is not less than 1 degree and not more than 10 degrees. |
US08564004B2 |
Complex primary optics with intermediate elements
A light emitter package comprising a light emitter disposed on a surface and a primary optic comprising an encapsulant disposed over the light emitter is disclosed. The package further comprises at least one intermediate element on the surface and at least partially surrounding the light emitter such that the intermediate element at least partially defines the shape of the primary optic. The intermediate element is configured so at least a portion of the intermediate element can be removed. |
US08564002B2 |
Organic light emitting display device and method for manufacturing the same
An organic light emitting display device and a method for manufacturing the same are provided. The organic light emitting display device includes a substrate including a capacitor region, a buffer layer disposed on the substrate, a semiconductor layer disposed on the buffer layer of the capacitor region, a gate insulation film formed on the semiconductor layer, and a transparent electrode formed on the gate insulation film of the capacitor region, wherein a cross-sectional width of the transparent electrode is smaller than a width of the semiconductor layer. |
US08564001B2 |
Organic light emitting device lighting panel
A first device that may include one or more organic light emitting devices. At least 65 percent of the photons emitted by the organic light emitting devices are emitted from an organic phosphorescent emitting material. An outcoupling enhancer is optically coupled to each organic light emitting device. In one embodiment, the light panel is not attached to a heat management structure. In one embodiment, the light panel is capable of exhibiting less than a 10 degree C. rise in junction temperature when operated at a luminous emittance of 9,000 lm/m2 without the use of heat management structures, regardless of whether the light panel is actually attached to a heat management structure or not. The light panel may be attached to a heat management structure. The light panel may be not attached to a heat management structure. |
US08563999B2 |
Light emitting device, light emitting device package and illumination system for reducing dislocation in semiconductor layer
A light emitting device is provided. The light emitting device includes a first semiconductor layer, an uneven part on the first semiconductor layer, a first nonconductive layer including a plurality of clusters on the uneven part, a first substrate layer on the nonconductive layer, and a light emitting structure layer. The light emitting structure layer includes a first conductive type semiconductor layer, an active layer and a second conductive type semiconductor layer on the first substrate layer. |
US08563997B2 |
Semiconductor light emitting device
A semiconductor light emitting device comprises a first nitride semiconductor layer comprising a flat top surface and a plurality of concave regions from the flat top surface, a reflector within the concave regions of the first semiconductor layer, and a second semiconductor layer on the first semiconductor layer. |
US08563995B2 |
Ultraviolet light emitting diode/laser diode with nested superlattice
A light emitting device with a template comprising a substrate and a nested superlattice. The superlattice has Al1-x-yInyGaxN wherein 0≦x≦α and 0≦y≦1 with x increasing with distance from said substrate. An ultraviolet light-emitting structure on the template has a first layer with a first conductivity comprising Al1-x-yInyGaxN wherein α≦x; a light emitting quantum well region above the first layer comprising Al1-x-yInyGaxN wherein α≦x≦b; and a second layer over the light emitting quantum well with a second conductivity comprising Al1-x-yInyGaxN wherein b≦x. The light emitting device also has a first electrical contact in electrical connection with the first layer, a second electrical contact in electrical connection with the second layer; and the device emits ultraviolet light. |
US08563989B2 |
Light emitting device with an electrode having an dual metal alloy
A manufacturing method of a light emitting device is provided. A first electrode is formed on a substrate. The first electrode includes a patterned conductive layer, and the patterned conductive layer includes an alloy containing a first metal and a second metal. An annealing process is performed on the first electrode, so as to form a passivation layer at least on a side surface of the first electrode. The passivation layer includes a compound of the second metal. A light emitting layer is formed on the first electrode. A second electrode is formed on the light emitting layer. |
US08563988B2 |
Semiconductor element and manufacturing method therefor
As viewed along a normal to the principal surface of a substrate 101, this semiconductor element 100 has a unit cell region 100ul and a terminal region 100f located between the unit cell region and an edge of the semiconductor element. The terminal region 100f includes a ring region 103f of a second conductivity type which is arranged in a first silicon carbide semiconductor layer 102 so as to contact with a drift region 102d. The ring region includes a high concentration ring region 103af which contacts with the surface of the first silicon carbide semiconductor layer and a low concentration ring region 103bf which contains an impurity of the second conductivity type at a lower concentration than in the high concentration ring region and of which the bottom contacts with the first silicon carbide semiconductor layer. A side surface of the high concentration ring region 103af contacts with the drift region 102d. As viewed along a normal to the principal surface of the semiconductor substrate, the high concentration ring region and the low concentration ring region are identical in contour. |
US08563983B2 |
Display panel, display device, and method manufacturing same
The invention provides a display panel and display device enabling easy connection to an external connection component depending on the type of a mounted component, and provides a display device manufacturing method allowing a simple manufacturing process. The display panel of the present invention is a display panel in which a thin film transistor array substrate and an opposed substrate are disposed opposing each other. The thin film transistor array substrate has a first routing wiring that is routed at the outer edge of the substrate, a common transfer section that is formed at a position overlapping with the first routing wiring when the substrate surface is viewed from a normal direction, and a first terminal region, having a plurality of terminals formed thereon including a terminal that is joined to the first routing wiring, at an end portion of the substrate. The opposed substrate has a second routing wiring, and a second terminal region, having a plurality of terminals formed thereon including a terminal that is joined to the second routing wiring, at an end portion of the substrate. The first routing wiring and the second routing wiring conduct with each other via the common transfer section. |
US08563980B2 |
Array substrate and manufacturing method
Manufacturing an array substrate includes forming data and gate lines which cross and a gate electrode on a substrate. The data line is discontinuously disposed to be separated from the gate line, or the gate line is discontinuously disposed to be separated from the data line. Active and gate insulating layers including bridge and source electrode vias are formed on the substrate. The bridge vias correspond to adjacent discontinuous sections of the data line or the gate line. The source electrode via corresponds to the data line. Pixel, source, and drain electrodes and a bridge line are formed on the substrate. The pixel electrode and the drain electrode are integral. The source electrode is connected to the data line through the source electrode via. The bridge line connects adjacent discontinuous sections of the data line or adjacent discontinuous sections of the gate line through bridge vias. |
US08563975B2 |
Hetero pn junction semiconductor and process for producing the same
A hetero pn junction semiconductor constituted of an electrically conductive polymer as a p-type semiconductor and an inorganic oxide as an n-type semiconductor, which is characterized in that the electrically conductive polymer is filled among nanoparticles of the inorganic oxide so as to satisfy the following Equation 1: Vp/Vn=X×σn/σp(0.1≦X≦10) |
US08563974B2 |
High-gain complementary inverter with ambipolar thin film transistors and fabrication thereof
The present invention relates to a high gain complementary inverter with ambipolar thin film transistors and fabrication thereof, comprising: a gate layer, a silica layer, a first active layer, a first source, a first drain, a second active layer, a second source and a second drain for fabrication cost and complexity reduction. |
US08563973B2 |
Semiconductor device
A semiconductor device including a nonvolatile memory cell including a writing transistor which includes an oxide semiconductor, a reading transistor which includes a semiconductor material different from that of the writing transistor, and a capacitor is provided. Data is written to the memory cell by turning on the writing transistor and supplying a potential to a node where a source electrode (or a drain electrode) of the writing transistor, one electrode of the capacitor, and a gate electrode of the reading transistor are electrically connected to each other, and then turning off the writing transistor so that a predetermined amount of charge is held at the node. Further, when a p-channel transistor is used as the reading transistor, a reading potential is a positive potential. |
US08563968B2 |
Electroluminescent device
The present invention provides an EL device that contains a quantum-dots-containing layer in which quantum dots hardly coagulate even under high-temperature conditions, e.g., at a temperature of 90° C. or more, that has a good performance even if heat treatment was carried at a high temperature in its production process, that can retain its emission characteristics for a prolonged period of time, and that has high durability. An electroluminescent device comprises a pair of electrodes, and an electroluminescent layer containing at least a luminescent layer, situated between the electrodes. The luminescent layer contains quantum dots whose surfaces are protected by one or more protective materials. At least one of the protective materials has a glass transition temperature and a melting point of 90° C. or more. |
US08563967B2 |
Organic functional device and manufacturing method therefor
An organic functional device (1; 40; 50) comprising a substrate (2) having a first electrode layer (3) and at least a first substrate shunt structure (6), at least a first organic functional layer (7) provided on top of the first electrode layer (3), a second, transparent electrode layer (8) arranged on top of the first organic functional layer (7). The organic functional device further comprises a plurality of mutually spaced apart second electrode shunting structures (9a-d) which are each in electrical contact with the second electrode layer (8) and with the first substrate shunt structure (6). |
US08563966B2 |
Nano metal particles based tunneling field effect transistor and nano-switch
A new devices structure of nano tunneling field effect transistor based on nano metal particles is introduced. The nano semiconductor device, comprising a source and a drain, wherein each of the source and drain comprise an implanted nano cluster of metal atoms, wherein the implanted nano cluster of metal atoms forming the source has an average radius in the range from about 1 to about 2 nanometers, and the implanted nano cluster of metal atoms forming the drain has an average radius in the range from about 2 to about 4 nanometers. Processes for producing the nano semiconductor device are detailed. |
US08563964B2 |
Light emitting semiconductor device
A semiconductor light emitting device is disclosed, which comprises: a substrate having a first surface and a second surface; a first semiconductor conductive layer is disposed on the first surface of the substrate; an insert layer is disposed on the first semiconductor conductive layer; an active layer is disposed on the insert layer; a second semiconductor conductive layer is disposed on the active layer; a first electrode is disposed on the second semiconductor conductive layer; and a second electrode is disposed on the second surface of the substrate, in which the electric of the second electrode is opposite to that of the first electrode. |
US08563963B2 |
Light-emitting diode die packages and methods for producing same
The present invention relates to a light-emitting diode die package. The LED die package includes a semiconductor base, at least two electrodes disposed on an electrode mounting surface of the semiconductor base, an insulation layer formed on the electrode-mounting surface and provided with two through holes for exposing the electrodes, a conductor-forming layer formed on the insulation layer and provided with two conductor-mounting holes in communication with the through holes, and conductor units formed within the through holes and the conductor-mounting holes in a manner electrically connected to the corresponding electrodes. The LED die package further includes a covering layer formed on a surface of the LED die opposite to the electrode-mounting surface and extending to an outer surface of the LED die. The covering layer is made of transparent material doped with phosphor powder. |
US08563962B2 |
Memory device and method of manufacturing the same
Disclosed is a memory device provided with a plurality of memory cells and a lead-out line (12) shared among the memory cells. Each memory cell is provided with a transistor (6) formed above a substrate (1) and a variable resistance element (10) having a lower electrode (7), an upper electrode (9) that comprises a noble metal, and a variable resistance layer (8) disposed between the lower electrode (7) and the upper electrode (9). The resistance value of the variable resistance layer (8) changes reversibly in response to electric pulses that go through the transistor (6) and are applied between the lower electrode (7) and the upper electrode (9). The lead-out line (12) is in direct contact with the upper electrodes (9) of the memory cells. |
US08563961B2 |
Semiconductor storage device and method for manufacturing same
Disclosed are a semiconductor storage device and a method for manufacturing the semiconductor storage device, whereby the bit cost of memory using a variable resistance material is reduced. The semiconductor storage device has: a substrate; a first word line (2) which is provided above the substrate; a first laminated body, which is disposed above the first word line (2), and which has the N+1 (N≧1) number of first inter-gate insulating layers (11-15) and the N number of first semiconductor layers (21p-24p) alternately laminated in the height direction of the substrate; a first bit line (3), which extends in the direction that intersects the first word line (2), and which is disposed above the laminated body; a first gate insulating layer (9) which is provided on the side surface of the N+1 number of the first inter-gate insulating layers (11-15) and those of the N number of the first semiconductor layers (21p-24p); a first channel layer (8p) which is provided on the side surface of the first gate insulating layer (9); and a first variable resistance material layer (7) which is provided on the side surface of the first channel layer. The first variable material layer (7) is in a region where the first word line (2) and the first bit line (3) intersect each other. Furthermore, a polysilicon diode (PD) is used as a selection element. |
US08563953B2 |
Charged particle beam writing apparatus and charged particle beam writing method
A charged particle beam writing apparatus includes a unit calculating a total charge amount of charged particle beams irradiating each minimum deflection region in deflection regions having different deflection sizes respectively deflected by deflectors of a plurality of levels for deflecting charged particle beams, a unit calculating a representative temperature of the each minimum deflection region based on heat transfer from other minimum deflection regions having been written before the each minimum deflection region is written, a unit inputting a first dose of a shot of each charged particle beam irradiating the each minimum deflection region, and modulating the first dose by using the representative temperature of the each minimum deflection region, and a unit including the deflectors of a plurality of levels and writing a pattern in the each minimum deflection region with a second dose, which has been modulated, by using the deflectors of a plurality of levels. |
US08563947B2 |
Integrative and real-time radiation measurement methods and systems
A method of determining the radiation type and energy distribution of a radiation source that outputs radiation. The method including providing a plurality of detector materials and exposing the plurality of detector materials to the radiation. Each of the plurality of detector materials stores a signal in response to being exposed to the radiation. The signals are representative of the radiation. The plurality of detector materials is stimulated to output the signals as measured signals. These measured signals are used to determine the radiation type and energy distribution of the radiation. |
US08563946B2 |
OLED phototherapy device
The invention provides a phototherapy device that includes a controlled environment defined by a plurality of transparent panels and at least one light emitting diode portion that projects light into the controlled environment. |
US08563944B2 |
Ion beam device
Provided is an ion beam device provided with a gas electric field ionization ion source which can prevent an emitter tip from vibrating in a non-contact manner. The gas electric field ionization ion source is comprised of an emitter tip (21) for generating ions; an emitter base mount (64) for supporting the emitter tip; an ionizing chamber which has an extraction electrode (24) opposed to the emitter tip and which is configured so as to surround the emitter tip (21); and a gas supply tube (25) for supplying gas to the vicinity of the emitter tip. The emitter base mount and a vacuum container magnetically interact with each other. |
US08563942B2 |
Multi-beam deflector array means with bonded electrodes
The invention relates to a multi-beam deflector array means for use in a particle-beam exposure apparatus employing a beam of charged particles, said multi-beam deflector array means having an overall plate-like shape with a membrane region and a buried CMOS-layer, said membrane region comprising a first side facing towards the incoming beam of particles and a second side opposite to the first side, an array of apertures, each aperture allowing passage of a corresponding beam element formed out of said beam of particles, and an array of electrodes, each aperture being associated with at least one of said electrodes and the electrodes being controlled via said CMOS layer, wherein the electrodes are pillared, standing proud of the main body of the multi-beam deflector array means, the electrodes being connected to one side of the main body of the multi-beam deflector array means by means of bonding connections. |
US08563940B2 |
Radiation detector manufacturing method, a radiation detector, and a radiographic apparatus
According to a radiation detector manufacturing method, a radiation detector and a radiographic apparatus of this invention, Cl-doped CdZnTe is employed for a conversion layer, with Cl concentration set to 1 ppm wt to 3 ppm wt inclusive, and Zn concentration set to 1 mol % to 5 mol % inclusive. This can form the conversion layer optimal for the radiation detector. Consequently, the radiation detector manufacturing method, the radiation detector and the radiographic apparatus can be provided which can protect the defect level of crystal grain boundaries by Cl doping in a proper concentration, and can further maintain integral sensitivity to radiation, while reducing leakage current, by Zn doping in a proper concentration. |
US08563935B2 |
Nuclear medicine imaging apparatus and control method
According to one embodiment, a nuclear medicine imaging apparatus includes a counting information collection unit, a determination unit, and a discarding unit. The counting information collection unit collects counting information including detection time of a gamma ray from a counting result output by a detector for counting light derived from a gamma ray, and stores the counting information in a buffer. The determination unit determines whether the volume of the counting information stored in the buffer exceeds a threshold. The discarding unit, in a case that the determination unit determines that the volume exceeds the threshold, intermittently discards, in chronological order, counting information whose detection time is within longer duration than predetermined duration used for generating two pieces of counting information obtained by counting pair annihilation gamma rays nearly coincidentally as coincidence counting information among the counting information collected from the detector. |
US08563934B2 |
Method and detection system for detection of aflatoxin in corn with fluorescence spectra
A system and method for fluorescence spectral imaging of target material to detect the presence of a contaminant (such as aflatoxin in corn) is provided. An ultraviolet light source is coupled with a light-excluding compartment. The fluorescence from the UV excited target passes through a filter (liquid crystal tunable, acoustic-optic tunable, a filter wheel, or other wavelength splitting device) and a lens, to a spectral imaging camera. Fluorescence spectral image data from the camera are analyzed by a computer and presented in human-readable form. Aflatoxin detection in contaminated corn kernels is based on peak fluorescence and peak fluorescence shift in the spectral range from 451 nm to 500 nm. Aflatoxin contamination level within the target material is quantified based on peak fluorescence and peak fluorescence shift and computed corn kernel pixel statistics. |
US08563929B2 |
Simultaneous dual band dual FOV imaging system
A two fields-of-view system has both fields of view imaged simultaneously to the same image plane. For example, an optical system comprising of two or more FOV where a common dual band focal plane array is used in order to image both spectral bands independently. Each spectral band is passed through a common imager, but split off by a beam splitter so that each spectral band sees a different field of view centered at the same point. The two fields of view are separated spectrally but enabled to be imaged simultaneously due to the spectral separation of the focal plane array and the use of a beam splitter. Such a system allows viewing two fields of view simultaneously. |
US08563928B2 |
Laser thermal imaging
Methods and apparatus for producing sub-diffraction limited images utilizing an exponential scaling effect. An exemplary system provides an optical source that focuses an optical beam onto a target. The focused optical beam has sufficient optical intensity to induce an exponential signal response within the target. A detection device detects the exponential signal response. A scanning device scans the focused optical source and another device records the detection of the exponential signal response for purposes of producing a sub-diffraction limited image. The system further includes a display device that displays at least a portion of the recorded detection. |
US08563927B2 |
Shielding member having a charge control electrode, and a charged particle beam apparatus
A shielding member for a charged particle beam apparatus includes a conductive substrate; and a through hole extending through the conductive substrate. The conductive substrate is comprised of a material having a specific electrical resistivity in a range from about 106 Ωcm to about 1012 Ωcm. |
US08563926B2 |
Method of making axial alignment of charged particle beam and charged particle beam system
A method of making axial alignment of a charged particle beam starts with obtaining at least first through sixth image data while controlling the focal position of the beam on a sample in the direction of incidence, the excitation current in a first alignment coil, and the excitation current in a second alignment coil. Then, values of the excitation currents in the first and second alignment coils for the axial alignment of the beam are calculated from the at least first through sixth image data. |
US08563925B2 |
Mass spectroscope and its adjusting method
In order to enable the mass spectroscope to reduce the operation load of the adjustment of the amplitude difference, and to reduce the increase in power consumption caused by the difference between the resonance frequency and the drive frequency, the resonance circuit unit of the ion trap section is configured to control the amplitude difference adjustment section of the resonance circuit unit to adjust that the amplitude difference between the high-voltage RF signals decreases, and controls the frequency synchronizing section of the resonance circuit unit to adjust that the resonance frequency of the resonance circuit is aligned with the drive frequency of the RF signal source, on the basis of the information about the amplitude difference between the high-voltage RF signals and the resonance frequency of the resonance circuit unit, which have been measured by a resonance frequency/amplitude difference measuring unit. |
US08563923B2 |
Orthogonal acceleration time-of-flight mass spectrometer
An orthogonal acceleration time-of-flight mass spectrometer has: an ion source for ionizing a sample; a conductive box into which the ions are introduced; ion acceleration device causing the ions to be accelerated in a pulsed manner in synchronism with a signal giving a starting point of measurement; and ion detector for detecting the ions in synchronism with the acceleration of the ions. The conductive box is provided with an ion injection port and an ion exit port. A lift voltage is applied to the conductive box. This voltage is switched in synchronism with the signal giving the starting point of the measurement. |
US08563921B2 |
Electron transfer dissociation device
A mass spectrometer is disclosed comprising an Electron Transfer Dissociation device comprising an ion guide. A control system determines the degree of fragmentation and charge reduction of precursor ions within the ion guide and varies the speed at which ions are transmitted through the ion guide in order to optimise the fragmentation and charge reduction process. |
US08563920B2 |
Mass spectrometer
A radio-frequency ion guide (20) for converging ions by a radio-frequency electric field and simultaneously transporting the ions into the subsequent stage is composed of eight rod electrodes (21 through 28) arranged in such a manner as to surround an ion optical axis (C). Each of the rod electrodes (21 through 28) is disposed at a tilt with respect to the ion optical axis (C) so that the radius r2 of the inscribed circle (29b) at the end face of the ion exit side is larger than the radius r1 of the inscribed circle (29a) at the end face of the ion injection side. Accordingly, the gradient of the magnitude or depth of the pseudopotential is formed in the ion's traveling direction in the space surrounded by the rod electrodes (21 through 28). Ions are accelerated in accordance with this gradient. Therefore, even in the case where the gas pressure is relatively high and ions have many chances to collide with gas, it is possible to moderate the ions' slowdown and prevent the ions' delay and stop. |
US08563912B2 |
Microscope having focus-holding unit
The invention relates to a microscope having a stage for supporting a sample to be examined, a recording sensor, an imaging optic for imaging the sample onto the recording sensor, a moving unit by means of which the distance between the stage and the imaging optic can be changed, a control unit for controlling an image recording of the sample and a focus-holding unit for maintaining a prescribed focal position for image recording of the sample at temporal intervals, wherein the focus-holding device comprises at least one hardware element and one software module, wherein the focus-holding unit is fully integrated in the control unit, on both the hardware and software sides. |
US08563910B2 |
Systems and methods for targeting a projectile payload
A projectile's payload is oriented (independently or by orientation of the projectile itself) toward a target just prior to firing (e.g., detonation of the payload), e.g., for munitions providing an increased kill and casualty area and a fire “in defilade” (left, right, backwards or at any angle) capability. |
US08563905B2 |
Method for controlling the induction heating system of a cooking appliance
A method for controlling an inductive heating system of a cooking hob provided with an induction coil is disclosed. The method controls it in connection with a predetermined working condition, comprises assessing the value of power absorbed by the system, measuring a temperature indicative of the thermal status of at least one element of the heating system, feeding the assessed power value to a computing model capable of providing an estimated value of temperature, comparing the measured temperature with the estimated temperature and tuning the computing model on the basis of such comparison. |
US08563903B2 |
Method and circuit for controlling radiant heat of transistor using metal-insulator transition device
Provided are a method and circuit for controlling heat generation of a power transistor, in which the power transistor can be protected by preventing heat generation of the power transistor by using a metal-insulator transition (MIT) device that can function as a fuse and can be semi-permanently used. The circuit for controlling heat generation of a transistor includes a metal-insulator transition (MIT) device in which abrupt MIT occurs at a predetermined critical temperature; and a power transistor connected to a driving device and controlling power-supply to the driving device, wherein the MIT device is attached to a surface or heating portion of the transistor and is connected to a base terminal or gate terminal of the transistor or a surrounding circuit from a circuit point of view, and wherein when a temperature of the transistor increases to a temperature equal to or greater than the predetermined critical temperature, the MIT device reduces or shuts off a current of the transistor so as to prevent heat generation of the transistor. |
US08563902B2 |
Heater control device and method for exhaust gas sensor
An oxygen concentration sensor is disposed in an engine exhaust passageway. The alcohol concentration in the fuel used in the internal combustion engine is detected. A target impedance is set on the basis of the detected alcohol concentration. The actual impedance of a sensor element of the oxygen concentration sensor is detected. The heater output of the exhaust gas sensor is controlled so that the actual impedance becomes equal to the target impedance, whereby the temperature of the sensor element represented by the impedance becomes equal to a target temperature represented by the target impedance. |
US08563899B2 |
Heated vehicle window
A heated vehicle window includes at least one ply of a glazing material, provided with an antenna and an array of electrical conductors forming a heating circuit. The heating circuit comprises a plurality of electrical conductors and at least two busbars for supplying direct electrical current to which the electrical conductors are connected. A discrete electrically conductive layer is provided to cover at least a portion of at least two of the busbars in direct current electrical isolation therefrom. The busbars and the discrete electrically conductive layer act as a capacitor in the presence of alternating electrical current. |
US08563896B2 |
Systems and methods to modify gas metal arc welding and its variants
A welding system and method includes a main torch including a main electrode configured to form a first arc with a base metal; a first bypass torch including a first bypass electrode configured to form a second arc with the main electrode; and a second bypass torch including a second bypass electrode configured to form a third arc with the main electrode. |
US08563893B2 |
Laser material processing system
A laser processing apparatus comprises a converging lens 31 for converging processing laser light and rangefinding laser light L2 toward a wafer 1, an actuator for actuating the lens 31, a shaping optical system 49 for adding astigmatism to reflected light L3 of the rangefinding laser light, a quadrant photodiode 42 for receiving the reflected light L3 and outputting voltage values corresponding to its light quantities, and a controller for regulating the actuator, and positions a converging point P2 of the rangefinding laser light L2 between a focal point P0 of the lens and the lens 31, so as to make it possible to form a modified region at a position deeper from the front face 3, thereby suppressing adverse effects due to the reflected light L3. The control is based on an arithmetic value subjected to a division by a sum of the voltage values, so as to prevent the arithmetic value from being changed by the quantity of reflected light. |
US08563892B2 |
Method and apparatus for laser engraving
A method and apparatus for laser engraving a three-dimensional pattern on a surface. A moveable laser head having a plurality of laser beams is provided. Preferably, the number of laser beams is four. Each beam is capable of being individually adjustably controllable. |
US08563889B2 |
Electrical discharge assembly and method for repairing diffusion cooling passages
An electrical discharge assembly for processing a workpiece having a cooling passage with first and second portions includes a first electrode having a first shape for machining the first portion of the cooling passage and a second electrode having a second shape for machining the second portion of the cooling passage. In a method for repairing cooling passages in a workpiece, a first electrode having a first shape is positioned in a cooling passage. The first electrode is electrically powered to machine a first portion of the cooling passage. A second electrode having a second shape is positioned in the cooling passage. The second electrode is electrically powered to machine a second portion of the cooling passage. |
US08563887B2 |
Electrical switching apparatus and trip latch assembly therefor
A trip latch assembly is provided for an electrical switching apparatus, such as a circuit breaker. The circuit breaker operating mechanism includes a pole shaft. The trip latch assembly includes a trip latch pivotably coupled to the circuit breaker housing and being movable between a latched position and an unlatched position. A trip latch reset spring is structured to bias the trip latch toward the latched position. A spring housing at least partially overlays the trip latch reset spring. A trip latch spring link includes a first end movably coupled to the pole shaft, and a second end cooperating with the spring housing. When the circuit breaker needs to be reset, the trip latch spring link engages the spring housing, in order apply torque to the trip latch reset spring. When the circuit breaker is closed, the bias of the trip latch reset spring on the trip latch is removed. |
US08563886B2 |
Key structure with scissors-type connecting member
A key structure with a scissors-type connecting member is provided. The scissors-type connecting member includes a first frame and a second frame. The first frame has a bulge. The second frame has a recess. The height of the bulge is smaller than the length of the recess entrance. The length of the recess bottom surface is greater than the length of the recess entrance. After the bulge of the first frame is introduced into the recess of the second frame, since the length of the recess bottom surface is greater than the length of the recess entrance, the possibility of detaching the bulge from the recess during the operation of the scissors-type connecting member will be minimized. |
US08563878B2 |
Grommet for a motor vehicle
The grommet disclosed includes a first diameter tubular section that allows a wire harness to pass through, and a second diameter tubular section that is provided on the first diameter tubular section. The first diameter tubular section is provided with an outer tubular section that extends in the axial direction. A projecting end of the outer tubular section is connected to the second diameter tubular section. A vehicle body latch portion is provided on an outer periphery or a resin inner of the second diameter tubular section. A grommet-pushing side of the first diameter tubular section is not secured to a wire harness. A grommet-inserting side of the first diameter tubular section is secured to the wire harness. The turning portion is deformed when the grommet is inserted into a through-hole in a vehicle body panel so that the first diameter tubular section is elongated. |
US08563875B2 |
Electromagnetic shielding layer and method for making the same
An electromagnetic shielding layer comprising at least one conductive layer and a carbon nanotube film structure, the conductive layer being disposed on the carbon nanotube film structure, and comes in contact with the carbon nanotube film structure electrically. A method for making the electromagnetic shielding layer includes the steps of: (a) providing an electronic element, the electronic element having a surface; (b) fabricating at least one carbon nanotube film; (c) forming a carbon nanotube film structure on the surface of the electronic element; and (d) forming a conductive layer on the carbon nanotube film structure, then obtaining an electromagnetic shielding layer on the surface of the electronic element. |
US08563871B2 |
Composite electronic parts
It is provided a composite electronic part having magnetic material and dielectric material and made by co-sintering at a temperature of 1000° C. or lower. The magnetic material comprises a ferrite comprising 46 to 48 mol % of Fe2O3, 0.1 to 36 mol % of ZnO, 10 to 14 mol % of CuO and the balance being NiO. The dielectric material has a dielectric constant of 1000 or higher, and comprises a barium titanate based dielectric material to which 0.5 to 4.0 weight parts of CuO and 4.0 to 9.0 weight parts of Bi2O3 are added with respect to 100 weight parts of the barium titanate based dielectric material. |
US08563861B2 |
Friction weld inner conductor cap and interconnection method
An inner conductor cap, with a connector end and a cable end, is provided with an inner conductor socket at the cable end and an inner conductor interface at the connector end. The inner conductor socket may be dimensioned to mate with a prepared end of an inner conductor of a coaxial cable. At least one material gap may be provided between a sidewall of the inner conductor socket and an outer diameter surface of the prepared end when the inner conductor cap is mated with the prepared end. A rotation key may be provided for rotating the inner conductor cap. |
US08563856B2 |
Electronic devices made with metal Schiff base complexes
The present invention relates to new electronic devices including a layer comprising a photoactive material and metal Schiff base complex, wherein the metal Schiff base complex is present as a host for the photoactive material or in a layer between the cathode and the photoactive material containing layer, or both. |
US08563855B2 |
Tandem photovoltaic cell
A photovoltaic element (110) for converting electromagnetic radiation into electrical energy is provided, which has a tandem cell structure. The tandem cell structure comprises the following: a dye solar cell (126) having a first electrode (118), an n-type semiconducting metal oxide (120), a dye (122) absorbing electromagnetic radiation in a first spectral range and a solid p-type semiconductor (124); and an organic solar cell (130) having an acceptor material (132) and a donor material (134), the acceptor material (132) and/or the donor material (134) comprising an organic material, the organic solar cell (130) furthermore comprising a second electrode (138) on an opposite side from the dye solar cell (126), and the organic solar cell being configured to absorb electromagnetic radiation in a second spectral range, which is at least partially different to the first spectral range, the first electrode (118) and/or the second electrode (138) being at least partially transparent for the electromagnetic radiation. |
US08563852B2 |
Solar cell having improved electron emission using amorphous diamond materials
Solar cells and related methods using thin layers of amorphous diamond. A thin layer of amorphous diamond is in electrical communication with a conductor. The use of a thin layer of amorphous diamond helps to reduce back conversion of excited electrons to heat. Reduced back conversion in turn can provide an increase in the efficiency of solar cells using the presently disclosed techniques. |
US08563850B2 |
Tandem photovoltaic cell and method using three glass substrate configuration
A tandem photovoltaic cell device is disclosed including an upper and lower cell. The lower cell may comprise a glass substrate and overlying layers that may include an electrode, absorber, window layer, and a transparent conductive oxide layer. The upper cell may comprise an intermediate glass substrate and overlying layers that may include a transparent conductor, an absorber, a window layer, a second conductive oxide layer, and an upper glass material. The cells may be coupled with an optical coupling material, and edge sealing material may be disposed between the glass substrates for both the upper and lower cells. |
US08563848B1 |
System and method for placement of photovoltaic strips
A method for forming a solar energy collection device includes receiving a sheet of glass, wherein the sheet of glass includes light concentrating geometric features, applying a light source to the light concentrating geometric features, determining physical concentration characteristics for each of the light concentrating geometric features in response to the light source that is applied, associating the physical concentration characteristics for each light concentrating geometric features with an identifier associated with the sheet of glass in a computer memory, determining placements for a plurality of PV strips relative to the sheet of glass in response to the physical concentration characteristics for each light concentrating geometric features stored in the computer memory, and securing the plurality of PV strips relative to the sheet of glass in response to the placements for the plurality of PV strips relative to the sheet of glass. |
US08563846B2 |
Thin film type solar cell and method for manufacturing the same
A thin film type solar cell and a method for manufacturing the same is disclosed, the thin film type solar cell comprising a substrate; a plurality of front electrodes on the substrate at fixed intervals by each first separating part interposed in-between; a plurality of semiconductor layers on the front electrodes at fixed intervals by each contact part interposed in-between; and a plurality of rear electrodes connected with the front electrodes through the contact part, provided at fixed intervals by each second separating part interposed in-between, wherein a main isolating part is formed in the outermost front electrode, the outermost semiconductor layer, and the outermost rear electrode, wherein an auxiliary isolating part is formed in at least one of the outermost front electrode and the outermost rear electrode, wherein the auxiliary isolating part is positioned on the inside of the main isolating part. |
US08563843B1 |
Electronic percussion device and method
An electronic percussion device including a drum shell, a drumhead as striking surface, vibration sensors, with a peripheral and a central vibration carrier. The vibration carriers abut against the drumhead to convey vibrations therefrom to the sensor(s). The central vibration carrier is a helicoidal spring. The peripheral vibration carrier is a rigid body of solid material supported by peripheral sensors disposed thereunder. The two electrical leads of each one of the peripheral sensors are correspondingly coupled in parallel to produce only two common output leads. An electronic sound module is configured to sample the sensors and employs software procedures to detect percussion strokes delivered on the drumhead, and to generate sounds accordingly. The software procedures use the averaged and aggregated signals to provide accurate detection of position and intensity of a drum stroke. Alternative embodiments of the device use only a peripheral vibration carrier or only a central vibration carrier. |
US08563839B2 |
Methods of reducing leaf senescence using methyl dihydrojasmonate
Methods for reducing leaf senescence in plants or plant portions by treating them with methyl dihydrojasmonate are disclosed. The methyl dihydrojasmonate may be in the form of an aqueous foliar spray, which may also include additives such as wetting agents, adjuvants, emulsifiers, dispersants, spreaders, surfactants, anchorage, disintegrants, and plant nutrients. |
US08563836B1 |
Maize variety inbred PH1CJ6
A novel maize variety designated PH1CJ6 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1CJ6 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1CJ6 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1CJ6 or a locus conversion of PH1CJ6 with another maize variety. |
US08563833B2 |
Plants and seeds of hybrid corn variety CH964539
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH964539. The invention thus relates to the plants, seeds and tissue cultures of the variety CH964539, and to methods for producing a corn plant produced by crossing a corn plant of variety CH964539 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH964539. |
US08563830B1 |
Maize variety inbred PH1C8A
A novel maize variety designated PH1C8A and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1C8A with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1C8A through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1C8A or a locus conversion of PH1C8A with another maize variety. |
US08563822B1 |
Soybean cultivar 15211129
A soybean cultivar designated 15211129 is disclosed. The invention relates to the seeds of soybean cultivar 15211129, to the plants of soybean cultivar 15211129, to the plant parts of soybean cultivar 15211129, and to methods for producing progeny of soybean cultivar 15211129. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 15211129. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 15211129, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 15211129 with another soybean cultivar. |
US08563819B1 |
Soybean cultivar NE0810220
The present invention is in the field of soybean variety NE0810220 breeding and development. The present invention particularly relates to the soybean variety NE0810220 and its progeny, and methods of making NE0810220. |
US08563818B1 |
Soybean variety XBP32006
A novel soybean variety, designated XBP32006 is provided. Also provided are the seeds of soybean variety XBP32006, cells from soybean variety XBP32006, plants of soybean XBP32006, and plant parts of soybean variety XBP32006. Methods provided include producing a soybean plant by crossing soybean variety XBP32006 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP32006, methods for producing other soybean varieties or plant parts derived from soybean variety XBP32006, and methods of characterizing soybean variety XBP32006. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP32006 are further provided. |
US08563817B2 |
Soybean variety XB22P11
A novel soybean variety, designated XB22P11 is provided. Also provided are the seeds of soybean variety XB22P11, cells from soybean variety XB22P11, plants of soybean XB22P11, and plant parts of soybean variety XB22P11. Methods provided include producing a soybean plant by crossing soybean variety XB22P11 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB22P11, methods for producing other soybean varieties or plant parts derived from soybean variety XB22P11, and methods of characterizing soybean variety XB22P11. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB22P11 are further provided. |
US08563806B2 |
Nematode inducible promotors and methods of use
The invention provides isolated promoter polynucleotides that are root-specific and/or induced by plant parasitic nematodes. The promoters of the invention are useful for controlling expression of nucleic acids of interest in plant roots and are particularly useful for controlling transcription of nucleic acids encoding agents that disrupt formation or maintenance of parasitic nematode feeding sites in plants. |
US08563805B2 |
Genetically modified reduced-browning fruit-producing plant and produced fruit thereof, and method of obtaining such
A genetically modified fruit-producing plant, said plant having sufficiently reduced total Polyphenol Oxidase (PPO) activity relative to a wild type of said plant to reduce browning in the fruit of said plant relative to said wild type, wherein the reduced total PPO activity results from a reduction in activity of at least two PPO isoenzymes in said plant relative to said wild type, or a cell, seed, seedling, part, tissue, cell, fruit or progeny of said plant. |
US08563802B2 |
Absorbent article with pattern
To apply a clear pattern to an absorbent article such as sanitary napkin without worsening the soft and comfortable touch to skin and allowing the colorant from coming into direct contact with the skin of a wearer.An absorbent article comprising a liquid-permeable sheet, a liquid-impermeable sheet, an absorber sandwiched between the liquid-permeable sheet and the liquid-impermeable sheet, and side sheets joined to at least a part of the right and left both sides of the liquid-permeable sheet and to at least a part of the liquid-impermeable sheet, wherein a plurality of recess parts are provided in the side sheet, at least the portion provided with the recess part has a colored layer between the side sheet and the liquid-permeable sheet, and the recess part appears in a color different from the portion other than the recess part. The recess part is provided by stacking the liquid-permeable sheet, the colored layer and the side sheet in this order and applying embossing from the side sheet side to the region where the colored layer is present. |
US08563801B2 |
System for detection of unfastening or removal of absorbent article from the body
A method for detecting and conveying an alarm signal, when an absorbent article is unfastened or, completely removed from the body of the wearer. The method is intended to be used in parallel with a method for detecting wetness in the absorbent article and further relates to an integrated detection-and-alarm method for detecting unfastening and/or wetness in an absorbent article. A system for detecting and conveying an alarm signal when an absorbent article is unfastened or removed from the body of the wearer and/or when the article is wet. The system includes (a) and absorbent article having at least one absorbent layer, the object to be displaced, such as a fastening system, one or more sensoring devices, one or more transmitting devices, and (b) a remote receiver. Furthermore, the system relates to the use of the system in the care of children and adults suffering from incontinence and/or psychological illnesses. |
US08563794B2 |
Extending the life of an aromatization catalyst
A method of extending the life of an aromatization catalyst comprising identifying a rapid deactivation threshold (RDT) of the catalyst, and oxidizing the catalyst prior to reaching the RDT. A method of aromatizing a hydrocarbon comprising identifying a rapid deactivation threshold (RDT) for an aromatization catalyst, and operating an aromatization reactor comprising the catalyst to extend the Time on Stream of the reactor prior to reaching the RDT. A method of extending the life of an aromatization catalyst comprising predicting a rapid deactivation threshold (RDT) for an aromatization reactor by employing the catalyst in a reactor system under an accelerated fouling condition to identify a test rapid deactivation threshold (t-RDT), predicting the RDT for the aromatization reactor based upon the t-RDT, and oxidizing the catalyst prior to the predicted RDT to extend the Time on Stream of the aromatization catalyst. |
US08563789B2 |
Process for the manufacture of hydrofluoroolefins
In this invention we are disclosing a process for the synthesis of hydrocchlorofluoro olefins (HCFO) and/or hydrofluoroolefins (HFO). The process is based on the steps of fluorination of hydrochloropropenes or hydrochloropropanes to form hydrochlorofluoropropenes and/or hydrofluoropropenes, followed by gas phase, catalytic fluorination of the hydrochlorofluoropropenes to form hydrofluoropropenes. |
US08563788B2 |
Recovery of butanol from a mixture of butanol, water, and an organic extractant
A process for recovering butanol from a mixture comprising a water-immiscible organic extractant, water, butanol, and optionally a non-condensable gas, is provided. The butanol is selected from 1-butanol, 2-butanol, isobutanol, and mixtures thereof. The extractant comprises at least one solvent selected from the group consisting of C7 to C22 fatty alcohols, C7 to C22 fatty acids, esters of C7 to C22 fatty acids, C7 to C22 fatty aldehydes, and mixtures thereof. |
US08563786B2 |
Method for producing optically active alcohol
Disclosed is a method for producing an optically active alcohol including reacting a titanium compound, an aromatic magnesium compound and a carbonyl compound in the presence of an optically active biphenol compound having a predetermined structure and an ether compound having a predetermined structure. |
US08563785B2 |
Method for isomerizing olefinically unsaturated alcohols
A process for isomerizing olefinically unsaturated alcohols over supported noble metal catalysts with a support based on carbon in an oxygenous atmosphere. |
US08563782B2 |
Producing α,β-unsaturated aldehydes by means of a reaction mixing pump
The invention relates to a method for producing α,β-unsaturated aldehydes, wherein a catalytic aldol condensation of charged aldehydes is carried out in the presence of an aqueous base within a continuous-flow reactor. The aim of the invention is to provide a method for aldolizing aldehydes that can be carried out in a particularly economical manner. The aim is achieved by using a reaction mixing pump as the reactor. |
US08563779B2 |
(4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides
A description is given of (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones of the formula (I) and of their use as herbicides. In this formula (I), X, R1, R2, R3, and R4 are radicals such as hydrogen and organic radicals such as alkyl. A and Z are oxygen or alkylene. |
US08563778B2 |
Process to prepare ethylene amines
The present invention relates to a process to prepare ethylene amines by the amination of ethylene oxide, ethylene glycol or ethanolamine in the presence of a catalyst, comprising a step wherein methylamine and/or ethylamine are removed from the reaction effluents. |
US08563774B2 |
Method for producing catalyst
Disclosed is a method for producing a catalyst, in which physical properties of a dried material or a calcined material in a production process of the catalyst are stable and a change in at least one of a catalyst activity and a selectivity to a target product is small and hence reproducibility of the catalyst is excellent. The present invention is a method for producing a catalyst containing molybdenum, bismuth, and iron, which contains the steps of washing a surface of at least one device equipped in an apparatus for the production of catalyst, to which a solid matter adheres, with a basic solution, and producing the catalyst with the apparatus for the production of catalyst thus washed. |
US08563773B2 |
Eductor-based reactor and pump around loops for production of acetic acid
Eductor mixers are used to mix the reaction medium in a carbonylation reactor. A portion of the reaction solution withdrawn from the reactor and directed through a pump around loop. The pump around loop is fed back to the reactor through the eductor mixers. In addition, a pump around loop may pass through one or more steam generators and/or heat exchangers. |
US08563771B2 |
Process for production of precursor compound for radioactive halogen-labeled organic compound
A process is provided for producing a labeled precursor which is useful for production of a radioactive fluorine-labeled amino acid compound. In the reaction step for introducing a leaving group to a mixture of syn-form and anti-form of FACBC, a base is allowed to present in the reaction system to produce a syn-leaving group adduct, which is unreactive with the base and is highly stable, and an anti-leaving group adduct which can react with the base to form a water-soluble compound. By employing a purification method utilizing such a difference in solubility, the syn-leaving group adduct can be separated selectively. The base may be a linear- or branched-chain primary to tertiary alkylamine having 1 to 10 carbon atoms, a nitrogen-containing heterocyclic compound with 2 to 20 carbon atoms, and a nitrogen-containing hetero aromatic compound with 2 to 20 carbon atoms. |
US08563770B2 |
Bis(formylphenyl) compound and novel polynuclear polyphenol compound derived from the same
A bis(formylphenyl) compound expressed by general formula (2) is useful as a photo-sensitive resist material: |
US08563769B2 |
Fluorine-containing compound, fluorine-containing surfactant and compositions containing same
A fluorine-containing compound exhibiting excellent surface tension-reducing ability despite the absence of perfluoroalkyl group having a chain length of 8 or more which had been the cause of the PFOS and PFOA problems and use of a fluorine material with low environmental load is provided. Also provided are a fluorine-containing surfactant and a composition thereof, an aqueous resin emulsion and a floor polish composition containing such surfactant. The fluorine-containing compound is represented by the following formula (1): Rf1—CpH2p—CH(OH)—CqH2q—NR—CrH2r—(O)n—SO3M (1) wherein Rf1 is a C1-6 perfluoroalkyl group, p, q, and r are independently an integer of 1 to 6, M is a cationic atom or atomic group, n is 0 or 1, R is hydrogen atom, a C1-12 alkyl group, or a group represented by the following formula (2): Rf2—CsH2s—CH(OH)—CtH2t— (2) wherein Rf2 is a C1-6 perfluoroalkyl group, and s and t are independently an integer of 1 to 6. |
US08563764B2 |
Catalyst composition including zirconium compounds for esterfication reaction and method for preparing ester compounds
The present invention relates to an esterification catalyst composition that includes a zirconium compound and a method for producing an ester compound, which includes the steps of esterifying alcohol and carboxylic acid compounds by using the same, and it may be applied to a mass synthesis process. |
US08563763B2 |
Composition, synthesis and use of isonitriles
The present invention relates to isonitrile compounds, methods of synthesis, and uses in a variety of fields. In one aspect, the present invention includes sulfinyl methyl isonitriles and methods for their preparation. In another aspect, the present invention includes the use of sulfinyl methyl isonitriles to prepare various other isonitrile compounds and derivatives thereof. In yet another aspect, the present invention includes a relatively simple and routine synthesis of sulfinyl methyl isonitrile compounds, other isonitrile compounds and derivatives thereof. |
US08563760B2 |
Process for the synthesis of long-chain fatty acids
This invention relates to processes for preparing long-chain fatty acids of Formula I: and salts thereof, as well as intermediates for the processes, wherein L1 and L2 are described herein. |
US08563756B2 |
Method and apparatus for preparing hydroxymethylfurfural
In an embodiment of the invention, an apparatus for preparing hydroxymethylfurfural (HMF) is provided. The apparatus includes a reaction area including a first organic layer including sugar and a solvent and a second organic layer including a solvent mixture with azeotropy and extractability, a boiling area including a mixing solution formed by the hydroxymethylfurfural and the solvent mixture, connected with the reaction area, and a distilling area including water and a liquid layer including the solvent mixture, connected to the reaction area. In another embodiment of the invention, a method for preparing hydroxymethylfurfural (HMF) is provided. |
US08563753B2 |
Microencapsulated catalyst
The present invention relates to a catalyst system. In particular the invention relates to a catalyst in the form of metal or an alloy that is encapsulated within a polymer shell or matrix. More specifically the invention is directed towards reactive catalytic metals that may be pyrophoric or otherwise reactive in air and/or susceptible to oxidation. In particular, the invention is concerned with catalysts based on nickel. |
US08563739B2 |
Ruthenium complexes having hybrid amine ligands, their preparation and use
The invention relates to a novel class of ruthenium complexes containing phosphine and hybrid amine ligands, their preparation and use as catalysts in the reduction of simple ketones to alcohols by molecular hydrogenation. The reactivity and enantioselectivity of such complexes in the asymmetric hydrogenation of simple ketones could be enhanced by the addition of some selective additives. |
US08563737B2 |
Methods of making bis-tridentate carbene complexes of ruthenium and osmium
Methods of making bis-tridentate carbene complexes of ruthenium and osmium are provided. The use of DMSO solvates of ruthenium(II) and osmium(II) halide salts provides good yields of the corresponding complexes. These materials may be used in OLEDs to provide devices having improved performance. |
US08563730B2 |
Pyrazole and fused pyrazole glucokinase activators
Compounds are provided for use with glucokinase that comprise the formula: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds. |
US08563729B2 |
Thienopyridone derivatives as AMP-activated protein kinase (AMPK) activators
The present invention relates to compounds of formula (I) wherein R1, R2 and R3 are as defined in claim 1, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention of diseases and disorders modulated by AMP agonists. The invention is also directed to intermediates and to a method of preparation of compounds of formula (I). |
US08563728B2 |
Process for the preparation of Dutasteride
The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5α-androst-1-en-3-one-17β-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I). |
US08563721B2 |
Morphinan derivatives and preparation methods thereof
The present invention relates to morphinan derivatives and preparation methods thereof, especially to ketal hydroxyl protected compounds of morphinan derivatives and preparation method thereof, and to a method for preparing corresponding alkylated morphinan derivatives by using the ketal hydroxyl protected compounds as intermediates, and more especially to a ketal hydroxyl protected compound of methylnaltrexone as intermediate for preparing methylnaltrexone and a method for preparing methylnaltrexone through said intermediate. |
US08563719B2 |
Process and intermediates for preparing lapatinib
The present invention provides a process for making lapatinib and its pharmaceutically acceptable salt by use of new intermediates. A new process for obtaining a pharmaceutical form of lapatinib ditosylate monohydrate is also provided. |
US08563718B2 |
Thiazolyl-pyrazolopyrimidine compounds as synthetic intermediates and related synthetic processes
The present invention relates to a synthetic intermediate of the formula: and its use in a synthetic process to make compounds of the formula |
US08563717B2 |
Adenine derivatives
The present invention relates to compounds of formula (I): wherein R1 is C1-6alkylamino, or C1-6alkoxy; R2 is a group having the structure: n is an integer having a value of 1 to 6; Het is a 6-membered saturated heterocycle containing one nitrogen atom wherein Het is attached to the —(CH2)n— moiety at any carbon atom of the heterocycle; R3 is hydrogen, C1-8alkyl, or C3-7cycloalkylC0-6alkyl; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants. |
US08563712B2 |
Hydroxy-substituted gold(III) porphyrin complexes as histone deacetylase inhibitors
A method for treatment of cancer by inhibiting the activity of histone deacetylase, comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of a gold(III) complex having the structural formula of or a pharmaceutically acceptable salt thereof, wherein: —R is selected from the group consisting of —OH, —CH2OH, C2H4OH, —C3H6OH or —C4H8OH; and X is independently a pharmaceutically acceptable counter-ion. |
US08563711B2 |
Nucleic acid aptamer capable of binding specifically to pancreatic cancer cells or tissues and use thereof
The present invention relates to a nucleic acid aptamer which can specifically recognize and bind to pancreatic cancer cells or tissues. The nucleic acid aptamer can bind specifically only to pancreatic cancer cells or tissues without binding to normal pancreatic cancer tissue, and thus can be effectively used as a composition for diagnosing and treating pancreatic cancer. In addition, the nucleic acid aptamer can detect not only the terminal pancreatic cancer cell line Capan-1, but also the early pancreatic cancer cell line Panc-1, and thus can be used for early diagnosis of pancreatic cancer, thereby contributing to increasing the survival rate of pancreatic cancer patients. |
US08563710B2 |
Modified oligonucleotide and its preparation and application
The present invention relates to a modified oligonucleotide, its preparation and application. The invention eables stabilizing the oligonucleotide by introducing a relatively small amount of modified nucleotide at specific UA/UA and/or CA/UG and/or UG/CA site of the oligonucleotide, therefore to decrease the modification-related cytotoxicity and compromising effects on the biological activity. |
US08563706B2 |
Efficient cell culture system for hepatitis C virus genotype 1A and 1B
The present inventors developed hepatitis C virus 1a/2a and 1b/2a intergenotypic recombinants in which the JFH1 structural genes (Core, E1 and E2), p7 and NS2 were replaced by the corresponding genes of the genotype Ia reference strain H77C or TN or the corresponding genes of the genotype Ib reference strain J4. Sequence analysis of recovered 1a/2a and 1b/2a recombinants from 2 serial passages and subsequent reverse genetic studies revealed adaptive mutations in e.g. p7, NS2 and/or NS3. In addition, the inventors demonstrate the possibility of using adaptive mutations identified for one HCV isolate in generating efficient cell culture systems for other isolates by transfer of mutations across isolates, subtypes or major genotypes. Furthermore neutralization studies showed that viruses of e.g. genotype 1 were efficiently neutralized by genotype Ia, 4a and 5a serum, an effect that could be utilized e.g. in vaccine development and immunological prophylaxis. The inventors in addition demonstrate the use of the developed systems for screening of antiviral substances in vitro and functional studies of the virus, e.g. identification of receptors required for HCV entry. |
US08563705B2 |
Ribonucleic acid binding motif protein 20 sequence variants
This document relates to methods and materials for using nucleic acid and amino acid sequence variants of ribonucleic acid binding motif protein 20 (RBM20). For example, methods and materials for using nucleic acid sequence variants and/or their corresponding amino acid variants of RBM20 that are associated with dilated cardiomyopathy to identify mammals (e.g., humans) at risk of having dilated cardiomyopathy that is likely to progress to heart failure are provided. |
US08563704B2 |
Peptide aptamer for neutralizing the binding of platelet antigen specific antibodies and diagnostic and therapeutic applications containing the same
The present invention relates to a peptide aptamer which mimics particularly the human platelet antigen HPA-Ia epitope present on the platelet GPIIb/IIIa molecules and which is capable of neutralizing the binding of HPA-I a specific antibodies (anti-HPA-1 a). This peptide aptamer is advantageously used in a method for detecting and identifying HPA-I a specific antibodies in human serum, in a diagnostic kit for screening and identifying antibodies, in an immunoassay and a pharmaceutical composition. |
US08563697B2 |
Anti-IL-12/IL-23 antibodies
The present invention provides an antibody comprising an antigen binding domain which binds to human IL-12 and human IL-23. The antibody binds human IL-12p40 existing as a monomer (human IL-12p40) and as a homodimer (human IL-12p80) and the antibody inhibits the binding of human IL-12 to human IL-12R β2 and human IL-23 to human IL-23R but does not inhibit the binding of human IL-12 or human IL-23 or human IL-12p40 or human IL-12p80 to human IL-12Rβ1. |
US08563696B2 |
Antibody specifically binding to c-Met
Antibodies specifically binding to c-Met protein, hybridoma cell lines, and compositions comprising the antibodies are disclosed herein. Methods of making and using the antibodies and compositions are also disclosed. |
US08563691B2 |
Lysosomal targeting peptides and uses thereof
The present invention provides further improved compositions and methods for efficient lysosomal targeting based on the GILT technology. Among other things, the present invention provides methods and compositions for targeting lysosomal enzymes to lysosomes using furin-resistant lysosomal targeting peptides. The present invention also provides methods and compositions for targeting lysosomal enzymes to lysosomes using a lysosomal targeting peptide that has reduced or diminished binding affinity for the insulin receptor. |
US08563680B2 |
Heat-aging-resistant polyamides
Thermoplastic molding compositions, comprising A) from 10 to 99.99% by weight of a polyamide B) from 0.01 to 20% by weight of a high-functionality polyetherol with an OH number of from 3 to 1350 mg KOH/g of polyetherol (to DIN 53240, part 2), C) from 0 to 70% by weight of further additives, where the total of the percentages by weight of components A) to C) is 100%. |
US08563679B2 |
Catalytic systems for the ring-opening (co)polymerization of lactones
The present invention relates to the use of a system composed of a base and of a sulphonamide, as a catalyst for the ring-opening (co)polymerization of lactones. The present invention also relates to novel sulphonamides and to a process for the ring-opening (co)polymerization of lactones comprising the use of sulphonamides in combination with a base as a catalytic system. |
US08563678B2 |
Photovoltaic cell with thiazole-containing polymer
Photovoltaic cells with thiazole-containing polymers, as well as related components, systems, and methods, are disclosed. |
US08563669B2 |
Olefin polymerization reactor, polyolefin production system, and polyolefin production process
An olefin polymerization reactor is provided with a first cylinder extending vertically; a first tapered cylindrical member placed in the first cylinder, having the inner diameter decreasing progressively downward, and having a gas inlet orifice at a bottom end thereof; a first liquid supplying part supplying a liquid so that the liquid may come into contact with an outer surface of the first tapered cylindrical member; and a gas supplying part supplying an olefin-containing gas through the gas inlet orifice into a first reaction region surrounded by an inner surface of the first tapered cylindrical member and an inner surface of the first cylinder above the first tapered cylindrical member, to form a spouted bed in the first reaction region. |
US08563668B2 |
Resin composition for laser engraving, relief printing plate precursor for laser engraving and process for producing same, and process for making relief printing plate
A resin composition is provided that includes two or more types of compounds selected from the group consisting of (Component A) a compound comprising a silicon atom having a total of one or two alkoxy and hydroxy groups, (Component B) a compound comprising a silicon atom having a total of three alkoxy and hydroxy groups, and (Component C) a compound comprising a silicon atom having a total of four alkoxy and hydroxy groups. There are also provided a relief printing plate precursor that includes a relief-forming layer formed from the resin composition, a process for producing a relief printing plate precursor that includes a layer formation step of forming a relief-forming layer from the resin composition and a crosslinking step of thermally crosslinking the relief-forming layer so as to form a crosslinked relief-forming layer. |
US08563662B2 |
Modified phenolic resins
The present invention relates to modified phenolic resins which contain silicic acid ester units. The modified phenolic resins may, for example, be used as components of a foundry binder system. The invention also relates to a method for producing such modified phenolic resins and to two-component binder systems which contain these modified phenolic resins. The invention furthermore relates to methods for producing foundry molds and foundry cores which contain the modified phenolic resins, and to the foundry molds and foundry cores themselves. |
US08563655B2 |
Film of poly(trimethylene arylate)/polystyrene blends and process for making
A film of poly(trimethylene arylate) and a polystyrene wherein the polystyrene concentration is in the range of 0.5 to 40 weight %. Poly(trimethylene terephthalate) and polystyrene are particularly useful. Also, disclosed are processes for preparing the film. |
US08563654B2 |
Golf ball
An object of the present invention is to provide a golf ball comprising a core and a cover, wherein the cover is made from a cover composition containing, as a resin component, a thermoplastic polyurethane (A) and a polyisocyanate mixture (B) in which a urethane prepolymer (b-1) having at least two isocyanate groups is dispersed in a thermoplastic resin (b-2) which does not substantially react with an isocyanate group; and wherein the cover composition has a slab hardness of more than 60 and not more than 75, and the cover has a thickness of 2.5 mm or less. |
US08563651B2 |
Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
The invention provides a method comprising the steps of providing a poly(ethylene glycol) having one terminal hydroxyl group; reacting the terminal hydroxyl group of the poly(ethylene glycol) with di(1-benzotriazolyl)carbonate to form a 1-benzotriazolylcarbonate ester of the poly(ethylene glycol); reacting the 1-benzotriazolylcarbonate ester of the poly(ethylene glycol) with an amino acid to form an amino acid derivative; and reacting the amino acid derivative with a biologically active agent under conditions to form a polymer-active agent conjugate. |
US08563649B2 |
Method of treating a material using a sol-gel derived composition
Disclosed is a method and system that includes treating a material by applying a sol-gel derived composition loaded with a first sorbate under conditions effective to treat the material with the first sorbate. |
US08563647B2 |
Multiple catalyst system for olefin polymerization and polymers produced therefrom
The present invention describes polymer comprising one or more C3 to C40 olefins and having a Mw of 100,000 or less and a Dot T-Peel of 1 Newton or more. The polymer may have a branching index (g′) of 0.95 or less measured at the Mz of the polymer, and a heat of fusion of 1 to 70 J/g. Also described are polymers of homopolypropylene or a copolymer of propylene and up to 5 mole % ethylene having: an isotactic run length of 1 to 30 as determined by Carbon 13 NMR and a percent of r dyad of greater than 20%, preferably from 20 to 70% as determined by Carbon 13 NMR. Also described are methods of making these and other polymers. |
US08563645B2 |
Thermoplastic resin composition and resin molded product
Process for preparing a thermoplastic resin composition containing an aromatic polycarbonate resin which may include a thermoplastic resin other than the aromatic polycarbonate resin, a granular talc, and optionally a rubber polymer, a flame retardant or a fluorinated polyolefin. The granular talc has a particle size in which a proportion of a 500 μm-mesh screen residue thereof is not less than 55% by weight. |
US08563644B2 |
Nitrile copolymer rubber composition and nitrile copolymer latex composition
A nitrile copolymer rubber composition obtained by coagulation of a nitrile copolymer latex composition comprised of a latex of a nitrile copolymer rubber (A) having α,β-ethylenically unsaturated nitrile monomer units in 55 to 80 wt % and cationic monomer units and/or monomer units able to form cations in which an inorganic filler (B) is dispersed is provided. Note that, preferably, the inorganic filler is a clay. According to the present invention, a nitrile copolymer rubber composition giving a nitrile copolymer rubber cross-linked product with an extremely low gasoline permeability and superior in sour gasoline resistance can be provided. |
US08563634B2 |
Inkjet ink including polyurethane
An inkjet ink composition includes: from 0.25 to 6 weight percent colorant; from 7 to 40 weight percent solvent; from 0.05 to 5 weight percent surfactant; and polyurethane binder in an amount of at least 0.5 weight percent of the inkjet ink composition but not more than twice the weight percent of the colorant. The polyurethane binder has a molecular weight from 32 K to 50 K and an acid number from 40 to 45. The polyurethane binder includes polyether polyol, aliphatic isocyanate and an acid group and does not include chain extenders. |
US08563633B2 |
Lignophenol derivative, resin composition, and resin molded article
A compound includes a lignophenol derivative having a weight average molecular weight in a range of 5000 to 10000, and satisfying the following formula (1): 3.0≦pH value≦4.5 (1) wherein the pH value is a determined value for a liquid mixture containing 0.2 g of the lignophenol derivative added to 40 ml of pure water. |
US08563632B2 |
Highly-filled sealant compositions
A sealant composition comprising a binder and a filler material. The binder comprising a residual pitch product and an elastomeric material and, optionally, asphalt, a microcrystalline wax, and/or oil. The filler material is present in an amount of between about 11 vol. % and about 67 vol. % of the sealant composition. In one embodiment, the filler material is present in an amount of between about 25 wt. % and about 70 wt. % of the sealant composition. |
US08563631B2 |
Viscosity-reducing super-plasticising copolymers
The invention mainly relates to the use of a (co)polymer having a main chain essentially consisting of (meth)acrylic units and polyoxyalkylated side-chains containing statistically-distributed hydrophobic units as an adjuvant for lowering the viscosity of hydraulic compositions. |
US08563629B2 |
Master batch method with optimized filler
The particle size distribution of a first fly ash is compared to an ideal particle size distribution that was empirically developed to provide a resin melt with a lower viscosity as more fly ash is added. A second fly ash material is similarly compared to the ideal curve and then is blended or optimized to provide an optimum filler for use with a suitable resin or similar material. The blended optimum filler is combined with a resin, an acid scavenger and an anti-oxidant to form a master batch which is available for mixing with other resins to form a material that is processed into a final product. Additional additives may be added for, among other things, foaming and coloration. |
US08563625B2 |
Hydrophilized curable silicone impression materials with improved storage behavior
The invention relates to hydrophilized curable silicone compositions which contain organopolysiloxanes, hydrophilizers and at least one stabilizing phosphorous compound. The compositions are particularly suitable as curable impression materials in dental applications, especially as wash impression materials. |
US08563622B2 |
Picolylamine resins
The present application relates to novel monodisperse, gel-type or macroporous picolylamine resins which are based on at least one monovinylaromatic compound and at least one polyvinylaromatic compound and/or a (meth)acrylic compound and contain tertiary nitrogen atoms in structures of the general formula (I) as functional group, where R1 is an optionally substituted radical from the group consisting of picolyl, methylquinoline and methylpiperidine, R2 is a radical —(CH2)q—COOR3, R3 is a radical from the group consisting of H, Na and K, m is an integer from 1 to 4, n and p are each, independently of one another, a number in the range from 0.1 to 1.9 and the sum of n and p is 2, q is an integer from 1 to 5 and M is the polymer matrix, a process for preparing them and their uses, in particular the use in hydrometallurgy and electroplating. |
US08563621B2 |
Blowing agents formed from nanoparticles of carbonates
The present invention relates to the preparation and use of a blowing agent in the form of of nanoparticles of an inorganic carbonate, and an acid. The acid is capable of being liquefied by heating to be reactive with the carbonate to release carbon dioxide that is useful as a blowing agent in all types of organic foams. The blowing agent, optionally pelletized in a suitable polymer carrier, is useful as a heat-activated blowing agent additive in polymer compositions. |
US08563608B2 |
Methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
The present invention relates to methods of reducing triglyceride levels in statin-treated subjects having a triglyceride level of 500 mg/dl to 1500 mg/dl. |
US08563606B2 |
Solid forms of selective androgen receptor modulators
The present invention relates to solid forms of (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide and process for producing the same. |
US08563603B2 |
Polycyclic compounds and methods related thereto
The invention relates to a novel compound of formula I or pharmaceutically acceptable salts thereof as well as pharmaceutical, nutraceutical, and botanical drug compositions and therapeutic methods related thereto. In certain embodiments, the compounds are used for the treatment of abnormal cell growth, hyperproliferative disorders, and inflammatory diseases in mammals. In other embodiments, the invention encompasses methods to isolate and synthesize the compounds. |
US08563602B2 |
Method of improving animal tissue quality by supplementing the animal diet with oleic acid and selected tocols
A novel method for improving the meat quality of an animal is provided. The method comprises feeding the animal a diet supplemented with oleic acid and selected tocols in amounts effective to improve the meat quality. The method may be practiced on non-ruminants and ruminants. |
US08563600B2 |
Diagnostic compounds
The Invention relates to conjugates of formula (III) or (IIIa), or a salt thereof, their use as radiopharmaceuticals, processes for their preparation, and synthetic intermediates used in such processes. |
US08563598B2 |
Beta-lactones as antibacterial agents
The present invention relates to specific beta-lactone compounds and compositions thereof for the treatment of infections, such as, e.g., infections with bacteria or infections with protozoa, in particular infections with Gram-positive and/or Gram-negative bacteria and of infectious diseases caused by or related to Gram-positive and/or Gram-negative bacteria, and to the modulation of virulence of Gram-positive and/or Gram-negative bacteria or of protozoa by specific beta-lactone compounds. The invention further relates to the use of the compounds or compositions for preventing or eliminating biofilms. |
US08563595B2 |
Treatment of cancer with complex organic-inorganic pigment compositions
The present invention includes compositions and methods for treating disorders of the skin or mucosa resulting from cancer therapies comprising: identifying a patient receiving cancer treatment; and administering to said patient an effective dose of a treated organic/inorganic complex material with an organic dye molecule or derivative thereof, in a pharmaceutically acceptable carrier. |
US08563594B2 |
S1P3 receptor inhibitors for treating pain
Disclosed herein are compositions and methods for treating pain using S1P3 receptor inhibitors. |
US08563591B2 |
Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein X represents C or N; Y represents C or N; L represents a methyl or a direct bond; Z1 represents a direct bond, C1-2alkyl- or a divalent radical of formula —CH2—CH═ (a) or —CH═ (b); Z2 represents a direct bond, C1-2alkyl- or a divalent radical of formula —CH2—CH═ (a) or —CH═ (b); R1 represents hydrogen, halo, cyano, amino, phenyl, hydroxy, C1-4alkyloxycarbonyl, hydroxycarbonyl, NR3R4 or C1-4alkyl optionally substituted with one or more substituents selected from hydroxycarbonyl, phenyl, C1-4alkyloxy or NR5R6 or R1 represents C1-4alkyloxy- optionally substituted with one or more substituents selected from hydroxycarbonyl, phenyl, C1-4alkyloxy or NR7R8; R2 represents hydrogen, halo, C1-4alkyl or C1-4alkyloxy-; R3 and R4 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-; R5 and R6 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-; R7 and R8 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-; A represents phenyl or a monocyclic heterocycle selected from the group consisting of thiophenyl, furanyl, oxazolyl, thiazolyl, imidazolyl, isoxazolyl, isothiazolyl, pyrridinyl, pyridazinyl, pyrimidinyl and piperazinyl. |
US08563588B2 |
Imidazolone derivatives, method for the preparation thereof and biological applications
Imidazolone derivatives, as medicaments, of formula wherein: R1═H, C1 to C5 alkyl, aryl or a 5- or 6-membered heterocyclic group; Ar1=optionally substituted aryl or an aromatic heterocycle; R═R2—S—, R3—HN—, R4COHN or Ar2, with R2=a C1-C5 alkyl, vinyl or vinyl(C1-C5)alkyl, nitrile or nitrile(C1-C5)alkyl, aryl or benzyl radical, which are optionally substituted; R3=the meanings given above and H; Ar2=substituted or unsubstituted aryl. |
US08563587B2 |
Methods and compositions for treating fish diseases
Therapeutic and prophylactic treatments of aquatic species and aquatic diseases through the controlled introduction of a heterocyclic N-halamine into an aquatic habitat. |
US08563585B2 |
Fullerene therapies for inflammation
Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene. |
US08563579B2 |
α-7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof
The present application is related to compounds represented by Formula I, which are novel allosteric modulators of α7nAChR. The application also discloses the treatment of disorders that are responsive to modulation of acetylcholine action on α7nAChR in a mammal by administering an effective amount of a compound of Formula I. |
US08563578B2 |
Antitumor properties of NO modified protease inhibitors
HIV-protease inhibitors, particularly saquinavir, showed strong anticancer activity but numerous side effects limited its application. In order to overcome its toxicity original compounds were modified by covalent attachment of NO. The efficacy of parental and NO-modified drug was compared in vitro and in vivo. Anticancer activities of NO-modified saquinavir (Saq-NO) was monitored in vitro using assay for cell viability, proliferation, necrotic, autophagic and apoptotic cell death, differentiation, expression of intracellular molecules such as cyclin D3, p53 and Akt. Antitumor properties and toxicity of the compound was estimated in vivo. Saq-NO abrogated the viability of large spectrum of human and rodent tumor cell lines with IC50 significantly lower than parental drug and expressed strong antimelanoma action in vivo. In contrast to saquinavir, there was no detectable toxicity against primary cells in vitro and in vivo. Saq-NO permanently diminished cell proliferation by induction of cell cycle block accompanied with minor presence of tumor cell death. Repressed proliferation was coordinated with strong activation of p53 and differentiation of C6 and B16 cells into oligodendrocytes or “Schwan” like cells, respectively. Oppositely to general characteristic of saquinavir to inhibit Akt signalling, Saq-NO treatment resulted in transient and intensive upregulation of Akt. This antagonism between parental and modified compound could be the crucial for switch of saquinavir from toxic to completely untoxic drug. |
US08563576B2 |
Tri-cyclic pyrazolopyridine kinase inhibitors
The present invention relates to compounds of tricyclic pyrazolopyridine useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. |
US08563574B2 |
Parenteral formulation of clopidogrel
Described herein are ways to solubilize clopidogrel for parenteral administration containing clopidogrel and a diluent NNDMA (N,N-dimethylacetamide); useful in the prevention of platelet aggregation in acute coronary syndrome, acute myocardial infarction or to prevent platelet facilitated thrombosis following coronary angioplasty and/or coronary stenting. |
US08563572B2 |
Quaternary opioid carboxamides
Compounds of formulas: are disclosed. The compounds are useful for ameliorating the side effects of therapeutic opiates. |
US08563571B2 |
Crystalline forms of oxymorphone hydrochloride
The present invention is directed to crystalline forms of oxymorphone hydrochloride. |
US08563569B2 |
Compositions and methods for inhibition of the JAK pathway
Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful. |
US08563568B2 |
Besylate salt of a BTK inhibitor
The present invention provides a salt form, and compositions thereof, useful as an inhibitor of one or more protein kinases and which exhibits desirable characteristics for the same. |
US08563563B2 |
Inhibitors of bruton's tyrosine kinase
Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. |
US08563560B2 |
Preparation of bicyclic guanidine salts in an aqueous media
Disclosed herein are bicyclic guanidine salts, useful as cure catalysts for electrodeposited coatings. The bicyclic guanidine salts are formed as the reaction product of reactants comprising (a) a compound having the general formula CXn, wherein X is N, O, or S and wherein n is 2 to 4; (b) an acid; (c) dipropylene triamine; and (d) water, and an associated method for forming a bicyclic guanidine salt from the same reaction ingredients. |
US08563549B2 |
Pyrimidine derivatives used as PI-3 kinase inhibitors
Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. |
US08563547B2 |
(6,7-dihydro-2-nitro-5H-imidazol[2,1-b][1,3]oxazin-6-yl) amide compounds, preparation methods and uses thereof
(6,7-Dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)amide compounds of formula (I), and their pharmaceutically acceptable salts, preparation methods and pharmaceutical compositions thereof are disclosed, wherein m and R are defined as in the description. The uses of the compounds in preparing medicaments for treating infectious diseases caused by Mycobacterium tuberculosis, especially infectious diseases caused by multi-drug resistance Mycobacterium tuberculosi are also disclosed. |
US08563546B2 |
Heterocyclic nitrogenous or oxygenous compounds with insecticidal activity formed from dialdehydes and their preparation and uses thereof
The heterocyclic nitrogenous or oxygenous compounds of formula (A), (B), (C) or (D) formed from dialdehydes, their optical isomers, cis- and trans-isomers, or agrochemically acceptable salts, their preparation methods, agrochemical compositions comprising the compounds and the uses thereof are provided. The compounds and their derivatives have high insecticidal activities to several farming and forestry pests including homoptera and lepidoptera pests, such as aphis, fulgorid, whitefly, leafhopper, common thrips, cotton bollworm, cabbage caterpillar, cabbage moth, cotton leafworm, armyworm and so on. |
US08563543B2 |
Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use
In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (a) and include tautomers, solvates, prodrugs, esters, and deuterates thereof, and pharmaceutically acceptable salts of said compounds, tautomers, solvates, prodrugs, esters, and deuterates, wherein each of R1, R2, R3, R4, R5, R9, ring A, ring B, ring C, m, n, p, q, -L1-, -L2-, L3-, and L4- is selected independently and as defined herein. The compounds of the invention have, surprisingly and advantageously, improved solution stability. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimers Disease, are also disclosed. |
US08563540B2 |
Pyrido[3,2-d]pyrimidine PI3K delta inhibitor compounds and methods of use
Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. |
US08563538B2 |
Preventing and/or treating cardiovascular disease and/or associated heart failure
Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such as idiopathic cardiomyopathy, metabolic cardiomyopathy which includes diabetic cardiomyopathy, alcoholic cardiomyopathy, drug-induced cardiomyopathy, ischemic cardiomyopathy, and hypertensive cardiomyopathy, (ii) atheromatous disorders of the major blood vessels (macrovascular disease) such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the femoral arteries, and the popliteal arteries, (iii) toxic, drug-induced, and metabolic (including hypertensive and/or diabetic disorders of small blood vessels (microvascular disease) such as the retinal arterioles, the glomerular arterioles, the vasa nervorum, cardiac arterioles, and associated capillary beds of the eye, the kidney, the heart, and the central and peripheral nervous systems, (iv) plaque rupture of atheromatous lesions of major blood vessels such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the fermoral arteries and the popliteal arteries, (v) diabetes or the complications of diabetes. |
US08563534B2 |
Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
Novel synthetic forms of etherified oxidized phospholipids and methods of utilizing same for preventing and treating atherosclerosis and other related disorders, as well as inflammatory disorders, immune mediated diseases, autoimmune diseases and proliferative disorders, are provided. In addition, methods of synthesizing etherified and esterified oxidized phospholipids and of using same for preventing and treating atherosclerosis and other related disorders are also provided. |
US08563529B2 |
RNAi therapeutic for treatment of hepatitis C infection
Small interfering RNAs (siRNAs) or small hairpin RNA (shRNAs) and compositions comprising same are provided that target human cyclophilin A (CyPA) to inhibit Hepatitis C (HCV) infection. Such siRNA and shRNAs may have a length of from about 19 to about 29 contiguous nucleotides corresponding to a specific region of human cyclophilin A (CyPA) cDNA of from about nucleotide 155 to about nucleotide 183 having particular potency against CyPA and HCV. Such siRNA and shRNAs may be formulated as naked compositions or pharmaceutical compositions. DNA polynucleotides, plasmids, and viral or non-viral vectors are provided that encode siRNA or shRNA molecules, which may be delivered directly to cells or in combination with delivery agents, such as lipids, polymers, encapsulated lipid particles, such as liposomes. Methods for treating, managing inhibiting, preventing, etc., HCV infection using such siRNA and shRNAs and compositions comprising same are also provided. |
US08563520B2 |
Treatment of ocular disease with inhibitors of alpha2 macroglobulin protein
The present invention relates to methods to treat glaucoma and glaucoma-related conditions through the regulation of changes in gene expression that are mediated by high intraocular pressure or α2 macroglobulin administration. Glaucoma, retinal ganglion cell (RGC) death and chronic ocular hypertension are treated using pharmaceutical compositions which comprise substances that inhibit the expression or activity of intraocular pressure-regulated early genes (IPREGs) or their gene products that are up-regulated by high intraocular pressure or α2 macroglobulin administration and/or which increase the expression or activity of IPREGs or their gene products that are down-regulated by high intraocular pressure or α2 macroglobulin administration. The invention also relates to methods of identifying an IPREG and methods to test for chronic ocular degeneration and the onset of RGC stress in an individual by measuring the expression level of IPREG proteins. |
US08563513B2 |
Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
Provided herein are Parathyroid hormone (PTH) peptides and parathyroid hormone-related protein (PTHrP) peptides (e.g., PTH analogs, PTHrP analogs), and related variants, chemical derivatives, fusion polypeptides, multimeric polypeptides, and peptidomimetics, peptoids, the like. Also provided are their use in methods for activating the PTH receptor in a cell (e.g., an osteoblast), methods of treating a subject with bone loss (e.g., by administration of a PTH peptide or PTHrP peptide (e.g., a PTH analog or PTHrP analog)), methods of ameliorating a symptom associated with osteoporosis in a subject, methods of retarding the progression of osteoporosis in a subject, and methods of regenerating bone in a subject. |
US08563501B2 |
Material for facilitating thermal treatments of biological tissues and method of energy targeting leading to thermal treatment of biological tissues
A method includes positioning an effective amount of a thermal target material at a treatment site of a patient. The treatment site, that is, the location of the thermal target material, comprises a location adjacent to biological tissue to be treated. The thermal target material includes carbon molecules preferably in a carrier fluid. Regardless of the particular structure of the carbon, the carbon molecules in the material heat very rapidly in response to incident microwave radiation and radiate heat energy. The heat energy radiated from an effective amount of the thermal target material when subjected to an effective quantity of microwave energy causes localized heating around the thermal target material. This localized heating may be applied for therapeutic purposes. However, the microwave radiation necessary to produce therapeutically effective heating is insufficient to cause cellular damage in the biological tissue by direct absorption in the tissue. |
US08563499B2 |
Fabric softener active composition
A fabric softener active composition, comprising from 65 to 95% by weight of a bis-(2-hydroxyethyl)-dimethylammonium chloride fatty acid ester having a molar ratio of fatty acid moieties to amine moieties of from 1.80 to 1.96, an average chain length of the fatty acid moieties of from 16 to 18 carbon atoms and an iodine value of from 0 to 50, from 2 to 8% by weight of a fatty acid triglyceride having an average chain length of the fatty acid moieties of from 10 to 14 carbon atoms and an iodine value of from 0 to 15, and from 3 to 12% by weight of an alcohol selected from ethanol, 1-propanol and 2-propanol has low melt viscosity, high stability towards dealkylation in the molten state and low flammability. |
US08563498B2 |
Fabric care compositions comprising copolymers
Fabric care composition comprising copolymers exhibit increased fabric active deposition and acceptable composition stringiness. |
US08563495B2 |
Resist remover composition and method for removing resist using same
There are provided a resist remover composition containing an amide solvent (A) represented by the following formula (1) and an organic amine compound (B), and a method for removing a resist using the resist remover composition, i.e., a resist remover composition that provides a sufficient removing capability even in a state where a resist is dissolved therein and is capable of being used for a prolonged period of time, and a method for removing a resist using the same. wherein R1 represents a linear, branched or cyclic alkyl group having from 1 to 6 carbon atoms; R2 and R3 each independently represent a linear or branched alkyl group having from 1 to 3 carbon atoms; and n represents an integer of from 0 to 2. |
US08563491B2 |
Methods of cleansing skin and rinse-off or wipe-off compositions therefor
Methods of cleansing skin comprise the steps of contacting the skin with a cleansing compositions comprising a fatty ester in combination with a lipid, and either rinsing the composition from the skin with water or wiping the composition from the skin with a dry or damp substrate. The cleansing compositions can comprise at least 8%, by weight of the composition, of fatty ester and/or further comprise a nonionic surfactant and less than about 50%, by weight of the composition, of an alcohol solvent such as ethanol, isopropanol, or mixtures thereof. The methods and compositions provide skin cleansing and hydration benefits. |
US08563489B2 |
Alkylated 1,3-benzenediamine compounds and methods for producing same
An alkylated 1,3-benzenediamine compound used as a deposit-control lubricant additives for organic materials including lubricating oil, gasoline, and diesel fuels. The invention improves the oxidative stability of the lubricants and fuels by adding the alkylated 1,3-benzenediamine compound. The alkylated 1,3-benzenediamine compound is formed using a catalytic hydrogenation that alkylates the 4 and/or 6 position of the central aromatic ring. |
US08563488B2 |
Functionalized polymer composition for grease
A grease composition containing: (a) the reaction product of: (i) a calcium containing overbased organic acid; and (ii) at least one acid producing compound or derivatives thereof selected from the group consisting of: (1) a non-polymeric hydrocarbyl substituted dicarbonyl derivative selected from the group consisting of an acid, an ester, a salt, an anhydride, ester-acid, acid-salt and mixtures thereof; (2) a copolymer derived from monomers containing (1) an olefin; and (2) an unsaturated dicarboxylic acid anhydride or derivatives thereof; and (3) an inorganic acid containing about 2 or more acidic hydrogens; and (b) an oil of lubricating viscosity, wherein the overbased calcium sulphonate contains colloidally dispersed calcium carbonate is selected from the group consisting of calcite, vaterite and mixtures thereof. The invention further relates to the process to make the composition and its use in greases to increase water resistance. |
US08563486B2 |
Lubricant composition and method for producing same
A lubricating oil composition comprising: a lubricating base oil comprising a first lubricating base oil component having a urea adduct value of not greater than 4% by mass, a kinematic viscosity at 40° C. of 14-25 mm2/s and a viscosity index of 120 or higher and a second lubricating base oil component having a kinematic viscosity at 40° C. of less than 14 mm2/s, wherein the content of the first lubricating base oil component is 10-99% by mass and the content of the second lubricating base oil component is 1-50% by mass, based on the total amount of the lubricating base oil; and a viscosity index improver, the lubricating oil composition having a kinematic viscosity at 100° C. of 4-12 mm2/s and a viscosity index of 200-350. |
US08563483B2 |
Mineral-based drilling fluid and drilling method
A high-temperature drilling fluid is disclosed based on brine and on a mixture of solids of controlled grain size, with water, dissolved salts and insoluble mineral solids comprising at least in part a weighting material of a grain size such that its D50 ranges between 1 and 25 μm and in part colloids of a grain size such that its D50 ranges between 0.2 and 2 μm. The total volume fraction of the solids ranges between 30 and 50% in relation to the total volume, and the total volume comprises at least 10% by volume of the colloids. |
US08563481B2 |
Corrosion inhibitor systems for low, moderate and high temperature fluids and methods for making and using same
A corrosion control system is disclosed including an anionic oxygen inhibitor, a cationic acid inhibitor or dispersant, and a noxious species inhibitor or scavenger for use in a fluid in contact with a metallic surface at low temperature, moderate temperature and especially at high temperature. A drilling fluid, a completion fluid, a production fluid and a geothermal fluid including an effective amount of the corrosion control system is also disclosed as well as methods for making and using same. |
US08563474B2 |
Pestcidal active mixtures comprising isoxazoline compounds I
The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one isoaxazoline compound I of the formula (I) wherein R1, R2, R3, R4, R5 and A are defined in the description; and 2) at least one active compound II selected from a group A comprising acteylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acteylcholine receptor agonists/antagonists, chloride channel activators, juvenile hormone mimics, compounds affecting the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipid synthesis and other compounds as defined in the description, in synergistically effective amounts. The invention relates further to methods and use of these mixtures for combating insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material as like seeds. |
US08563461B2 |
Method to activate a catalyst for a continuous process for the preparation of phenol from benzene in a fixed bed reactor
A process to activate a titanium silicalite catalyst for the oxidation of benzene to phenol is provided. The catalyst is activated in the reactor for the oxidation by feeding to a reactor containing the titanium silicalite catalyst, during a time of from 2 to 6 hours, at a temperature ranging from 20 to 120° C., an aqueous solution of ammonium acid fluoride in a concentration ranging from 0.1% to 1% by weight; and hydrogen peroxide in a concentration ranging from 3% to 10% by weight; feeding water to the reactor at the end of the reaction; and drying or calcining the catalyst contained in the reactor to obtain the activated catalyst. The catalyst is represented by the formula: xTiO2.(1−x)SiO2 wherein x is from 0.0001 to 0.04. |
US08563460B2 |
Shaped heterogeneous catalysts
A catalyst unit is described comprising a cylinder with a length C and a diameter D, wherein said unit has five holes arranged in a pentagonal pattern extending longitudinally therethrough, with five flutes running along the length of the unit, said flutes positioned equidistant adjacent holes of said pentagonal pattern. The catalyst may be used particularly in steam reforming reactors. |
US08563458B2 |
Catalyst systems and polymerization processes
A method of polymerizing olefins with catalyst systems, such as, for example, a multimodal catalyst system, wherein the catalyst system is stored at a controlled temperature to minimize loss of catalyst system productivity. |
US08563447B2 |
Silver-containing wound care device
Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The finish may be applied to a target substrate, such as a fiber, fabric, film, foam, hydrogel, or hydrocolloid to provide a single layer antimicrobial wound care device. Alternatively, a silver-containing layer may be combined with one or more additional layers of target substrate to provide a composite antimicrobial wound care device. The device may also contain an odor-absorbing component capable of reducing or eliminating odors that are inherently associated with infectious wounds. Also provided is a method for making the wound care device and a composition of matter comprising the silver-based antimicrobial finish. |
US08563445B2 |
Conformal layers by radical-component CVD
Methods, materials, and systems are described for forming conformal dielectric layers containing silicon and nitrogen (e.g., a silicon-nitrogen-hydrogen (Si—N—H) film) from a carbon-free silicon-and-nitrogen precursor and radical-nitrogen precursor. The carbon-free silicon-and-nitrogen precursor is predominantly excited by contact with the radical-nitrogen precursor. Because the silicon-and-nitrogen film is formed without carbon, the conversion of the film into hardened silicon oxide is done with less pore formation and less volume shrinkage. The deposited silicon-and-nitrogen-containing film may be wholly or partially converted to silicon oxide which allows the optical properties of the conformal dielectric layer to be selectable. The deposition of a thin silicon-and-nitrogen-containing film may be performed at low temperature to form a liner layer in a substrate trench. The low temperature liner layer has been found to improve the wetting properties and allows flowable films to more completely fill the trench. |
US08563440B2 |
Method for chemically treating a substrate
A method for chemically treating a disc-shaped substrate having a bottom surface, a top surface and side surfaces by contacting a process medium that is fluid-chemically active with at least the bottom surface of the substrate. The substrate is moved relative to the process medium while forming a triple line between the substrate, the substrate medium and the atmosphere surrounding the substrate and medium. In order to chemically remove errors, particularly in the side surfaces, relative motion should be carried out while avoiding a contacting of the process medium with the top surface of the substrate, where the triple line is formed at a desired height of the side surface facing away from the process medium flow side in relation to the relative motion between the substrate and the process medium. |
US08563438B2 |
Method for manufacturing semiconductor device
A manufacturing method of a semiconductor device of which cost can be suppressed by using a nanoimprinting method is provided. In the invention, a gate insulating film, a conductive film, and a resist are formed in sequence over a semiconductor film and a resist is hardened while pressing a mold formed with a pattern to the resist. Therefore, the pattern is transferred to the resist, the surface of the resist to which the pattern is transferred is ashed until a part of the conductive film is exposed, the resist having the ashed surface is used a mask, and the conductive film is etched. |
US08563437B2 |
Method for treating group III nitride semiconductor
The invention discloses a treating method to produce various patterns on the surface by using gases with ability to etch the group III nitride semiconductor in certain conditions. The selective etching makes some specific patterns on group III nitride semiconductor surface, and different forms of the patterns can be controlled by the selective etching conditions. |
US08563436B2 |
Chemical mechanical polishing composition and methods relating thereto
A method for chemical mechanical polishing of a semiconductor wafer containing a nonferrous metal is provided, comprising: providing a chemical mechanical polishing composition comprising 1 to 25 wt % of an oxidizer; 0.01 to 15 wt % of an inhibitor for the nonferrous metal; 0.005 to 5 wt % of a copolymer of poly(ethylene glycol) methyl ether(meth)acrylate and 1-vinylimidazole; and water; wherein the chemical mechanical polishing composition has an acidic pH; providing a chemical mechanical polishing pad; providing a semiconductor wafer containing the nonferrous metal; creating dynamic contact between the chemical mechanical polishing pad and the semiconductor wafer; and, dispensing the polishing solution at or near the interface between the chemical mechanical polishing pad and the semiconductor wafer. |
US08563432B2 |
Method for forming through silicon via structure
A method for forming a TSV structure includes providing a silicon substrate with an interlayer dielectric layer formed thereon, forming a hard mask structure including a first hard mask layer including a metal element on the interlayer dielectric layer and a second hard mask layer on the first hard mask layer; forming an opening through the hard mask structure and the interlayer dielectric layer, the opening has a bottom and sidewalls in the silicon substrate. The method further includes depositing an insulating material on the hard mask structure and on the bottom and the sidewalls of the opening, subsequently removing the insulating material and the second hard mask layer until the first hard mask layer is exposed, and filling a conductive material into the opening. The method also includes removing the conductive material and the first hard mask layer by a CMP process until the interlayer dielectric layer is exposed. |
US08563431B2 |
Method for manufacturing semiconductor device
In a manufacturing process of a semiconductor device, a manufacturing technique for reducing the number of lithography processes using a photoresist and simplifying the process is provided, and the throughput is improved. An etching mask for forming a pattern of a layer to be processed such as a conductive layer or a semiconductor layer is manufactured without using a lithography technique that uses a photoresist. The etching mask is formed of a stacked layer structure of a light absorption layer and an insulating layer utilizing laser ablation by laser beam irradiation through a photomask. |
US08563429B2 |
Methods of forming a metal silicide layer for semiconductor devices
Methods of forming a metal silicide layer are provided that include exposing polysilicon through just dry etching (JDE) and recessesing an oxide layer through chemical dry etching (CDE). In particular, dry etching is primarily performed to an extent to expose the polysilicon. Then, CDE is secondarily performed to expose the polysilicon. The CDE process includes selecting an etchant source among combinations of NF3 and NH3, HF and NH3, and N2, H2, and NF3, dissociating the etchant source, forming an etchant of NH4F and NH4F.HF through the dissociation, producing solid by-products of (NH4)2SiF6 through the reaction between the etchant and an oxide at a low temperature, and annealing the by-products at a high temperature such that the by-products are sublimated into gas-phase SiF4, NH3, and HF. |
US08563423B2 |
Fluorine depleted adhesion layer for metal interconnect structure
A line trough and a via cavity are formed within a dielectric layer comprising a fluorosilicate glass (FSG) layer. A fluorine depleted adhesion layer is formed within the line trough and the via cavity either by a plasma treatment that removes fluorine from exposed surfaces of the FSG layer, or by deposition of a substantially fluorine-free dielectric layer. Metal is deposited within the line trough and the via cavity to form a metal line and a metal via. The fluorine depleted adhesion layer provides enhanced adhesion to the metal line compared with prior art structures in which a metal line directly contacts a FSG layer. The enhanced adhesion of metal with an underlying dielectric layer provides higher resistance to delamination for a semiconductor package employing lead-free C4 balls on a metal interconnect structure. |
US08563421B2 |
Method of fabricating semiconductor device
A method of forming a dielectric layer having an air gap to isolate adjacent wirings or a gate stack of the semiconductor device is provided. A method of fabricating a semiconductor device includes providing a semiconductor substrate on which a plurality of wirings are formed adjacent to one another and forming a dielectric layer filling an upper portion of a space between the adjacent wirings to form air gaps by a thermal chemical vapor deposition method. |
US08563419B2 |
Method of manufacturing an interconnect structure and design structure thereof
A method of manufacturing the IC is provided, and more particularly, a method of fabricating a cap for back end of line (BEOL) interconnects that substantially eliminates electro-migration (EM) damage. The method includes forming an interconnect in an insulation material, and selectively depositing a metal cap material on the interconnect. The metal cap material includes RuX, where X is at least one of Boron and Phosphorous. |
US08563415B2 |
Semiconductor device and method of manufacturing the same
The present invention relates to a method of manufacturing a semiconductor device. After depositing the metal gate electrode material, a layer of oxygen molecule catalyzing layer having a catalyzing function to the oxygen molecules is deposited, and afterwards, a low-temperature PMA annealing process is used to decompose the oxygen molecules in the annealing atmosphere into more active oxygen atoms. These oxygen atoms are diffused into the high-k gate dielectric film through the metal gate to supplement the oxygen vacancies in the high-k film, in order to alleviate oxygen vacancies in the high-k film and improve the quality of the high-k film. According to the present invention, the oxygen vacancies and defects of high-k gate dielectric film will be alleviated, and further, growth of SiOx interface layer having a low dielectric constant caused by the traditional PDA high temperature process may be prevented. Thereby, the EOT of the entire gate dielectric layer may be effectively controlled, and the MOS device may be continuously scaled. Meanwhile, the present invention further provides a semiconductor device obtained according to the above-mentioned method. |
US08563406B2 |
Semiconductor substrate, semiconductor device, and manufacturing methods for them
The present invention provides a semiconductor substrate, which comprises a singlecrystalline Si substrate which includes an active layer having a channel region, a source region, and a drain region, the singlecrystalline Si substrate including at least a part of a device structure not containing a well-structure or a channel stop region; a gate insulating film formed on the singlecrystalline Si substrate; a gate electrode formed on the gate insulating film; a LOCOS oxide film whose thickness is more than a thickness of the gate insulating film, the LOCOS oxide film being formed on the singlecrystalline Si substrate by surrounding the active layer; and an insulating film formed over the gate electrode and the LOCOS oxide film. On this account, on fabricating the semiconductor device having a high-performance integration system by forming the non-singlecrystalline Si semiconductor element and the singlecrystalline Si semiconductor element on the large insulating substrate, the process for making the singlecrystalline Si is simplified. Further, the foregoing arrangement provides a semiconductor substrate and a fabrication method thereof, which ensures device isolation of the minute singlecrystalline Si semiconductor element without highly-accurate photolithography, when the singlecrystalline Si semiconductor element is transferred onto the large insulating substrate. |
US08563404B2 |
Process for dividing wafer into individual chips and semiconductor chips
A process to divide a wafer into individual chips is disclosed. The process (1) etches semiconductor layers for an active device to form two grooves putting the virtual cut line therebetween, where the semiconductor wafer is to be divided along the virtual cut line; (2) etches the substrate in a region including the virtual cut line but offset from the groove from the back surface thereof so as to expose the semiconductor layers in the primary surface; and (3) etches the semiconductor layer exposed in step (2). |
US08563403B1 |
Three dimensional integrated circuit integration using alignment via/dielectric bonding first and through via formation last
A method includes forming a first integrated circuit (IC) device having a first substrate, an alignment via defined in the first substrate, a first wiring layer over the alignment via, and a first bonding layer over the first wiring layer; forming a second IC device having a second substrate, a second wiring layer over the second substrate, and a second bonding layer over the second wiring layer; bonding the first bonding layer of first IC device to the second bonding layer of second IC device; thinning a backside of the first IC device so as to expose the alignment via; and using the exposed alignment via to form a deep, through substrate via (TSV) that passes through the first IC device, through a bonding interface between the first IC device and second IC device, and landing on the second wiring layer of the second IC device. |
US08563397B2 |
Semiconductor device and manufacturing method thereof
The present invention relates to a semiconductor device and its manufacturing method including the steps of: forming a first semiconductor element layer having a first wiring over a substrate; forming a second semiconductor element layer having a second wiring and fixed to a first structure body having a first sheet-like fiber body, a first organic resin, and a first electrode; preparing a second structure body having a second sheet-like fiber body, a second organic resin which is not cured, and a second electrode; disposing the second structure body between the first and second semiconductor element layers so that the first wiring, the second electrode, and the second wiring are overlapped with each other over the substrate; and curing the second organic resin. |
US08563396B2 |
3D integration method using SOI substrates and structures produced thereby
A process and resultant article of manufacture made by such process comprises forming through vias needed to connect a bottom device layer in a bottom silicon wafer to the one in the top device layer in a top silicon wafer comprising a silicon-on-insulator (SOI) wafer. Through vias are disposed in such a way that they extend from the middle of the line (MOL) interconnect of the top wafer to the buried oxide (BOX) layer of the SOI wafer with appropriate insulation provided to isolate them from the SOI device layer. |
US08563389B2 |
Integrated circuit having silicon resistor and method of forming the same
An embodiment of the disclosure includes a method of forming an integrated circuit. A substrate having an active region and a passive region is provided. A plurality of trenches is formed in the passive region. A root mean square of a length and a width of each trench is less than 5 μm. An isolation material is deposited over the substrate to fill the plurality of trenches. The isolation material is planarized to form a plurality of isolation structures. A plurality of silicon gate stacks and at least one silicon resistor stack are formed on the substrate in the active region and on the plurality of isolation structures respectively. |
US08563387B2 |
Transistor and method of manufacturing a transistor
In accordance with an embodiment of the present invention a transistor is disclosed. The transistor comprises a collector, a base and an emitter, wherein a first end width of the base is larger than a middle width of the base, wherein a first end width of the collector is larger than a middle width of the collector, or wherein a first end width of the emitter is larger than a middle width of the emitter. |
US08563374B2 |
Strained semiconductor devices having asymmetrical heterojunction structures and methods for the fabrication thereof
Embodiments of a strained semiconductor device are provided, as are embodiments of a method for fabricating such a strained semiconductor device. In one embodiment, the method includes providing a partially-fabricated semiconductor device including a semiconductor substrate having a source side and a drain side, a gate stack formed on the semiconductor substrate, and a channel region formed within the semiconductor substrate beneath the gate stack and extending from the source side to the drain side of the semiconductor substrate. A cavity is produced in only one of the source side and the drain side of the semiconductor substrate, and a strain-inducing material is formed within the cavity to create an asymmetric heterojunction structure within the semiconductor substrate. |
US08563373B2 |
Semiconductor device having vertical channels and method of manufacturing the same
A method of manufacturing a semiconductor device which can prevent leakage current caused by gate electrodes intersecting element isolation layers in a major axis of an active region, and which further has vertical channels to provide a sufficient overlap margin, and a semiconductor device manufactured using the above method. The device includes gate electrodes formed on element isolation layers that are disposed between active regions and have top surfaces that are higher than the top surfaces of the active regions. Since the gate electrodes are formed on the element isolation layers, leakage current in a semiconductor substrate is prevented. In addition, the gate electrodes are formed using a striped shape mask pattern, thereby obtaining a sufficient overlap margin compared to a contact shape or bar shape pattern. |
US08563371B2 |
Method of forming semiconductor device
Provided is a method of forming a semiconductor device. The method may include forming a first insulating layer on a semiconductor substrate. A first polycrystalline silicon layer may be formed on the first insulating layer. A second insulating layer may be formed on the first polycrystalline silicon layer. A second polycrystalline silicon layer may be formed on the second insulating layer. A mask pattern may be formed on the second polycrystalline silicon layer. The second polycrystalline silicon layer may be patterned using the mask pattern as an etch mask to form a second polycrystalline silicon pattern exposing a portion of the second insulating layer. A sidewall of the second polycrystalline silicon pattern may include a first amorphous region. The first amorphous region may be crystallized by a first recrystallization process. The exposed portion of the second insulating layer may be removed to form a second insulating pattern exposing a portion of the first polycrystalline silicon layer. The exposed portion of the first polycrystalline silicon layer may be removed to form a first polycrystalline silicon pattern exposing a portion of the first insulating layer. The exposed portion of the first insulating layer may be removed to form a first insulating pattern exposing a portion of the semiconductor substrate. |
US08563370B2 |
Method for fabricating surrounding-gate silicon nanowire transistor with air sidewalls
A method for fabricating a surrounding-gate silicon nanowire transistor with air sidewalls is provided. The method is compatible with the CMOS process; the introduced air sidewalls can reduce the parasitic capacitance effectively and increase the transient response characteristic of the device, thus being applicable to a high-performance logic circuit. |
US08563369B2 |
CMOS with channel P-FinFET and channel N-FinFET having different crystalline orientations and parallel fins
A method for fabricating an integrated circuit with at least one p-FinFET device and at least one n-FinFET device. The method includes bonding a first silicon layer having a first crystalline orientation to a second silicon layer having a second crystalline orientation that is different from the first crystalline orientation. A first plurality of fins and a second plurality of fins are created. A spacer is formed around each fin in the first plurality of fins and second plurality of fins. A set of regions of the second layer between each fin in the first plurality of fins and the second plurality of fins are recessed to form a base with exposed sidewalls under each fin in the first plurality of fins and the second plurality of fins. The base under each fin and a set of exposed regions between each fin is oxidized. |
US08563368B2 |
Thin film transistor array panel and method for manufacturing the same
A thin film transistor substrate according to an embodiment of the present invention includes: an insulation substrate; a gate line formed on the insulation substrate; a first interlayer insulating layer formed on the gate line; a data line and a gate electrode formed on the first interlayer insulating layer; a gate insulating layer formed on the data line and gate electrode; a semiconductor formed on the gate insulating layer and overlapping the gate electrode; a second interlayer insulating layer formed on the semiconductor; a first connection formed on the second interlayer insulating layer and electrically connecting the gate line and the gate electrode to each other; a drain electrode connected to the semiconductor; a pixel electrode connected to the drain electrode; and a second connection connecting the data line and the semiconductor to each other. |
US08563364B2 |
Method for producing a power semiconductor arrangement
In a method for producing a power semiconductor arrangement, a dielectric insulation carrier with a top side and a top metallization layer arranged on the top side are provided. Also provided are a semiconductor chip and at least one electrically conductive contact pin, each pin having a first end and an opposite second end. The semiconductor chip is sintered or diffussion soldered to the top metallization layer. Between the first end and the top metallization layer an electrically conductive connection is formed, in which electrically conductive connection material of the contact pin is in direct physical contact with the material of the top metallization layer. |
US08563359B2 |
Method for manufacturing semiconductor device, and semiconductor substrate
A method for manufacturing a semiconductor device includes forming at least one stripe-shaped protection film over a multilayer film in a scribe region of a semiconductor substrate having a plurality of semiconductor element regions formed therein, the protection film having a thickness larger in a center portion thereof than at an end surface thereof and being made of a member which transmits a laser beam, and removing the multilayer film in the scribe region by irradiating the protection film with a laser beam. |
US08563357B2 |
Method of packaging a die
A method of attaching a die to a substrate is disclosed. A major surface of the die has an array of electrical contacts, and is covered with a tape segment having an array of apertures in register with the contacts. Solder balls are inserted into the apertures. The die is positioned against a substrate with the solder balls in register with the die pads on the surface of the substrate, and a heat treatment process is performed to bond the conductive elements to the corresponding bond pads. |
US08563353B2 |
Method of making a multicomponent film
Described herein is a method and liquid-based precursor composition for depositing a multicomponent film. In one embodiment, the method and compositions described herein are used to deposit Germanium Tellurium (GeTe), Antimony Tellurium (SbTe), Antimony Germanium (SbGe), Germanium Antimony Tellurium (GST), Indium Antimony Tellurium (IST), Silver Indium Antimony Tellurium (AIST), Cadmium Telluride (CdTe), Cadmium Selenide (CdSe), Zinc Telluride (ZnTe), Zinc Selenide (ZnSe), Copper indium gallium selenide (CIGS) films or other tellurium and selenium based metal compounds for phase change memory and photovoltaic devices. |
US08563352B2 |
Creation and translation of low-relief texture for a photovoltaic cell
Low-relief texture can be created by applying and firing frit paste on a silicon surface. Where frit contacts the surface at high temperature, it etches silicon, dissolving silicon in the softened glass frit. The result is a series of small, randomly located pits, which produce a near-Lambertian surface, suitable for use in a photovoltaic cell. This texturing method consumes little silicon, and is advantageously used in a photovoltaic cell in which a thin silicon lamina comprises the base region of the cell. When the lamina is formed by implanting ions in a donor wafer to form a cleave plane and cleaving the lamina from the donor wafer at the cleave plane, the ion implantation step will serve to translate texture formed at a first surface to the cleave plane, and thus to the second, opposing surface following cleaving. Low-relief texture formed by other methods can be translated from the first surface to the second surface in this way as well. |
US08563349B2 |
Method of forming semiconductor device
A method of forming a semiconductor device includes preparing a semiconductor substrate having a plurality of chips formed thereon and a scribe lane disposed between the chips, simultaneously forming a groove having a first depth in the scribe lane, and a through hole penetrating the chips and having a second depth. The chips are separated along the groove. The first depth is smaller than the second depth. |
US08563347B2 |
Method for producing a thin-film photovoltaic cell having an etchant-resistant electrode and an integrated bypass diode and a panel incorporating the same
A method for producing a thin-film solar cell with a cell level integrated bypass diode includes forming at least first, second and third series-connected cells on a support, each cell being a laminated structure comprising a junction layer including semiconducting material of a first and second type, a front electrode formed of a transparent conductive oxide resistant to an etchant disposed in electrical contact with the semiconducting material of the first type, and a back electrode in electrical contact with the semiconducting material of the second type. A portion of both the back electrode and the junction layer are separated from a selected parent solar cell. Using the separated portion of the back electrode the semiconducting material of the second type of the separated portion of the junction layer is connected to the semiconducting material of the first type of any one chosen solar cell in the array. |
US08563346B2 |
Method for manufacturing electrode of dye-sensitized solar cell and dye-sensitized solar cell having electrode thereof
The present invention provides a method for manufacturing an electrode of a dye-sensitized solar cell using an inkjet printing process, an electrode formed thereby, and a dye-sensitized solar cell having the electrode. According to the method, a metal electrode is formed by jetting an ink solution containing nano metal powder on a transparent substrate or a transparent substrate in which a barrier layer is deposited to improve coating performance of a transparent conductive layer. A transparent conductive layer is formed on the transparent substrate on which the metal electrode is formed. The transparent conductive layer protects the metal electrode from liquid electrolyte. |
US08563345B2 |
Integration of structurally-stable isolated capacitive micromachined ultrasonic transducer (CMUT) array cells and array elements
A method for forming a capacitive micromachined ultrasonic transducer (CMUT) includes forming multiple CMUT elements in a first semiconductor-on-insulator (SOI) structure. Each CMUT element includes multiple CMUT cells. The first SOI structure includes a first handle wafer, a first buried layer, and a first active layer. The method also includes forming a membrane over the CMUT elements and forming electrical contacts through the first handle wafer and the first buried layer. The electrical contacts are in electrical connection with the CMUT elements. The membrane could be formed by bonding a second SOI structure to the first SOI structure, where the second SOI structure includes a second handle wafer, a second buried layer, and a second active layer. The second handle wafer and the second buried layer can be removed, and the membrane includes the second active layer. |
US08563342B2 |
Method of making semiconductor optical integrated device by alternately arranging spacers with integrated device arrays
A method of making a semiconductor optical integrated device includes the steps of forming, on a substrate, a plurality of semiconductor integrated devices including a first optical semiconductor element having a first bonding pad and a second optical semiconductor element; forming a plurality of bar-shaped semiconductor optical integrated device arrays by cutting the substrate, each of the semiconductor optical integrated device arrays including two or more semiconductor optical integrated devices; alternately arranging the plurality of semiconductor optical integrated device arrays and a plurality of spacers in a thickness direction of the substrate so as to be fixed in place; and forming a coating film on a facet of the semiconductor optical integrated device array. Furthermore, the spacer has a movable portion facing the first bonding pad, the movable portion protruding toward the first bonding pad and being displaceable in a protruding direction. |
US08563340B2 |
Method for manufacturing light emitting chip
A method for manufacturing light emitting chips includes steps of: providing a substrate having a plurality of separate epitaxy islands thereon, wherein the epitaxy islands are spaced from each other by channels; filling the channels with an insulation material; sequentially forming a reflective layer, a transition layer and a base on the insulation material and the epitaxy islands; removing the substrate and the insulation material to expose the channels; and cutting the reflective layer, the transition layer and the base to form a plurality of individual chips along the channels. |
US08563336B2 |
Method for forming thin film resistor and terminal bond pad simultaneously
Disclosed are methods for forming a thin film resistor and terminal bond pad simultaneously. A method includes simultaneously forming a terminal bond pad on a terminal wire and a thin film resistor on two other wires. |
US08563331B2 |
Process for fabricating and repairing an electronic device
A process for forming an electronic device can include fabricating an electronic device having a first workpiece including a first electronic component that includes a first organic layer. The process can also include repairing the electronic device after fabrication to provide electrical connections for initial non-functional electrical elements. |
US08563328B2 |
Fiber-optic biosensor and biosensing methods
A method for biosensing that includes passing, via convective flow, a sample believed to contain one or more target biomarkers through a microfluidic channel and over the surface of an optical waveguide that has been prepared to bind the one or more target biomarkers, and sensing for an emission output from the optical waveguide at a wavelength that is characteristic of the binding of the target biomarker. A biosensor device that includes a module defining at least one microfluidic channel, an optical waveguide exposed along at least a portion of its length to fluid flow within the microfluidic channel, where a surface of the optical waveguide being prepared to bind a target biomarker, and an excitation source to couple an excitation wavelength of light into the optical waveguide. The device also includes a sensor for detecting emission light from the optical waveguide at an emission wavelength characteristic of binding of the target biomarker. |
US08563320B2 |
Optical cell
A use composition monitor determines the concentration of peracid and/or peroxide in a use composition using a kinetic assay procedure. A sample mixture containing a sample of the use composition, a diluent and at least one reagent is prepared and analyzed using, for example, an optical detector. A reduced-turbulence optical detector can be used to improve collected response data. A reduced-turbulence optical detector can include a cell body disposed about a length of transparent tubing. The cell body positions one or more emitter/receiver pairs about the transparent tubing. Thus, tube junctions are eliminated and sample flow within the tube is substantially turbulence free. |
US08563317B2 |
Apparatus for detecting gamma hydroxybutyrate, ketamines and related drugs in beverages
Apparatus for detecting the presence of foreign substances in a beverage. The apparatus for detecting the presence of Gamma-hydroxybutyrate or other drugs in a beverage comprises apparatus wherein cobalt nitrate, oxammonium chloride/ferric chloride, oxammonium sulphate/ferric chloride, 5% ferric chloride, saturated potassium dichromate, toluene/cobalt thiocyanate, chromium (IV) oxide/sulphuric acid carbodiimide salts in combination with oxammonium salts and ferric chloride, or lacmoid is supported on a substrate. The apparatus for detecting the presence of ketamines or other drugs in a beverage comprises apparatus wherein modified-Dragendorff Reagent is supported on a substrate. |
US08563310B2 |
Methods for promoting hematopoietic reconstitution
The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that either increase HSC numbers or decrease HSC numbers as desired by a particular indication. For example, HSC modulators found to increase HSC numbers include prostaglandin E2 (PGE2) and agents that stimulate the PGE2 pathway. Conversely, HSC modulators that prevent PGE2 synthesis decrease HSC numbers. HCS modulators may be used in vitro, in vivo, or ex vivo. |
US08563305B2 |
Rapid generation of antibodies
High efficient methods for producing an antibody molecule that binds an antigen are described. The methods include obtaining a population of PBMC enriched for CD19highCD3negCD20low to negCD38highCD27high cells from a mammal exposed to an antigen from sample of cells enriched for PBMC. The cells are isolated from a sample obtained at a time that the fraction of PBMC expressing antibody reactive to the antigen is at a high level. Sequences encoding heavy and light chain variable domains are prepared in a manner that allow production of molecules with natural heavy and light chain pairing. |
US08563301B2 |
Bioreactor systems and associated methods of processing bioreactor vessels
A bioreactor processing unit (10) includes at least one cell culture module (200) comprising: a base (202) including a receiving station (204) for removably receiving a plurality of bioreactor vessels (400) at respective locations (206); and a clamp plate (240). The clamp plate (240) is removably connectable to the base (202). The system further includes a drive mechanism (226) and multiple fluid conduits. When the system is to be used for an experiment run, vessels (400) are loaded into the receiving station (204) and the clamp plate (240) is connected to the base (202), forming a connection between the drive mechanism and the vessels, for transmitting input motion from the drive mechanism (226) into multiple rotary motion outputs for turning a stirrer (416) in each vessel (400). At the same time, connection of the clamp plate to the base forms a fluid connection between the multiple fluid conduits and an input port (412) in each respective vessel via associated multiple outlet ports (256) in the clamp plate and associated fluid connectors. The system further includes at least one sensor (126a, 126b) that is mounted so as to be movable to a position adjacent to each respective vessel location (206) for monitoring the contents of each vessel (400). |
US08563298B2 |
NMR systems and methods for the rapid detection of analytes
This invention features systems and methods for the detection of analytes, and their use in the treatment and diagnosis of disease. |
US08563297B2 |
Controllable binding and dissociation of chemical entities and electrode devices therefore
Disclosed are methods for controlling molecular interactions where at least one member of a pair of chemical entities having a pH-dependent affinity is immobilized on the surface of an electrode. By changing the potential difference between the electrode and a counter electrode, the affinity of the pair of chemical entities is changed, changing the tendency of the pair to bind or to dissociate. Disclosed are also devices useful for implementing the methods of the present invention. |
US08563296B2 |
Processes and systems for discharging amine byproducts formed in an amine-based solvent
Embodiments of a process for discharging amine byproducts formed in an amine-based solvent are provided. The process comprises the steps of contacting the amine-based solvent with flue gas comprising carbon dioxide, oxygen, nitrogen, NOx, SOx, or mixtures thereof to form a carbon dioxide-laden amine-based solvent that contains the amine byproducts. Carbon dioxide is separated from the carbon dioxide-laden amine-based solvent to form a carbon dioxide-depleted amine-based solvent. The amine byproducts from the carbon dioxide-depleted amine-based solvent are fed to an algae source. |
US08563295B2 |
Lactic acid bacteria and their use in swine direct-fed microbials
TRFs useful for identifying strains of interest are provided. A method of identifying one or more strain that can be used as a direct-fed microbial is also provided. One or more strain identified by the method is additionally provided. A method is also provided for administering to an animal an effective amount of the one or more strain. Additionally provided is an isolated strain chosen from at least one of Lactobacillus acidophilus strain PlB c6 (NRRL B-50103), Lactobacillus salivarius strain o246e 33w (NRRL B-50102), Pediococcus acidilactici strain o246e 42 (NRRL B-50171), and Pediococcus acidilactici strain PlJ e3 (NRRL B-50101). An isolated strain having all of the identifying characteristics of one of the strains listed above is also provided. One or more strain can be administered as a direct-fed microbial to an animal. Methods of preparing a direct-fed microbial are also provided. |
US08563294B2 |
Photocatalytic hydrogen production in cyanobacteria
A cyanobacterial cell comprising a PSI complex which accepts electrons from at least one respiratory cytochrome is disclosed. Methods of generating same and use of same for the production of hydrogen gas are also disclosed. |
US08563292B2 |
Preparation of vanillin from microbial transformation media by extraction by means supercritical fluids or gases
Crude solid vanillin-containing material is precipitated from a solution obtained by biotransformation, and purified by a process comprising contacting it with a purification fluid selected from (a) a liquefied gas whose pressure exceeds its critical pressure and whose temperature is below its critical temperature; (b) a supercritical fluid; (c) a gas. The fluid is preferably liquid carbon dioxide. The temperature is maintained below 25° . The product may be further purified by treatment with CO2 in a fluid bed drier. The crude material is preferably one precipitated from a solution resulting from biotransformation of ferulic acid. A new strain of Amycolatopsis capable of generating high concentrations of vanillin with minimal odoriferous by-products (e.g. guaiacol) is also disclosed. |
US08563290B2 |
Pectate lyase variants
The present invention relates to pectate lyase variants exhibiting alterations relative to a parent enzyme exhibiting pectate lyase activity as its major enzymatic activity; to a method of producing such enzymes; and to methods for using such enzymes in the textile, detergent and cellulose fiber processing industries. Compared to the parent enzyme, the pectate lyase variants of the present invention exhibit improved stability in detergents. |
US08563289B2 |
Protease variants
The present invention relates to methods for producing variants of a parent RP-II protease and the variants having altered properties as compared to the parent RP-II protease. |
US08563288B2 |
Removal of plasmin or plasminogen from cryoprecipitate
A method for specifically removing or isolating plasmin(ogen) or plasmin in presence of fibrinogen from a mixture containing plasmin(ogen) or plasmin by contacting the mixture with a rigid amino acid wherein the amino group of the amino acid and the carboxylic group of the amino acid are about 6-8 Angstroms, preferably about 7 Angstroms apart and the rigid amino acid is covalently bound to the support via the amino group of the amino acid. |
US08563283B2 |
Strains of Escherichia coli modified by metabolic engineering to produce chemical compounds from hydrolyzed lignocellulose, pentoses, hexoses and other carbon sources
The present invention refers to the new Escherichia coli strains denominated JU15, JU15A, LL26 and MS04 and their derivatives that produce metabolites, particularly D-lactate, L-lactate or ethanol, with high yield and selectivity from a wide variety of carbon sources, such as culture media with a high xylose content (as the main carbon source) and, in particular, media formulated with hydrolyzed vegetables, such as sugarcane bagasse, agave bagasse and fast-growing grasses, and a wide variety of agricultural and industrial wastes, such as whey or forestry wastes, celluloses, grasses, agave bagasse, paper wastes, shavings and sawdust, shrubs and generally any material derived from lignocellulose. These strains use the production of the metabolite of interest (especially D-lactate, L-lactate or ethanol) as the only way of regenerating the reducing power. The invention also refers to fermentation methods to produce these metabolites from media with a diversity of carbon sources, including glucose, lactose or xylose. |
US08563281B2 |
Method for production of polyester copolymer using recombinant microorganism
The object of the present invention is to provide a method for efficiently producing a polyester copolymer consisting of 3-hydroxybutyrate and lactate via microbial fermentation with the use of a sugar as a starting material. The method may comprise culturing a recombinant microorganism expressing: a protein capable of catalyzing the transfer of CoA to propionic acid and/or lactate; a protein capable of catalyzing the formation of acetoacetyl-CoA from two acetyl-CoA molecules; a protein capable of catalyzing acetoacetyl-CoA reduction; and a protein capable of catalyzing polyhydroxyalkanoate synthesis. According to the production method, a polyester copolymer consisting of 3-hydroxybutyrate and lactate can be efficiently produced using an inexpensive carbon source as a starting material, and thus the production cost of a biodegradable plastic can be reduced. |
US08563280B2 |
Nicotianamine-derived metallophore and processes for producing same
The invention relates to a nicotianamine derivative and to a process for chemical or enzymatic synthesis thereof. The nicotianamine derivative has the following formula (I). The invention finds use in the pharmacy field in particular. |
US08563279B2 |
Convergent synthesis of renin inhibitors and intermediates useful therein
Described is a method for the preparation of renin inhibitors such as aliskiren, and intermediates useful therein. The method introduces a nitrogen-containing intermediate such as a lactone of formula (8). with R4 being a branched C3—6 alkyl. In the preparation of the lactone, or related intermediates, a desired stereochemical configuration can be controlled by starting from a chiral aldehyde satisfying formula (10). |
US08563274B2 |
Compositions and methods for intramolecular nucleic acid rearrangement
Aspects of the present invention are drawn to processes for moving a region of interest in a polynucleotide from a first position to a second position with regard to a domain within the polynucleotide, also referred to as a “reflex method”. In certain embodiments, the reflex method results in moving a region of interest into functional proximity to specific domain elements present in the polynucleotide (e.g., primer sites and/or MID). Compositions, kits and systems that find use in carrying out the reflex processes described herein are also provided. |
US08563273B2 |
Method of screening for compounds that disaggregate amyloid aggregates
A peptide comprising at least 5 amino acid residues and less than 15 amino acid residues, the peptide including an amino acid sequence as set forth in SEQ ID NO: 7 as well as pharmaceutical compositions, kits and methods for diagnosing and treating amyloid associated diseases. |
US08563268B2 |
Polypeptide having tyrosinase activity
The present invention relates to isolated polypeptides having tyrosinase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
US08563265B2 |
Analytical instrument and method for evaluating microbial contamination of an object
An instrument and method for ascertaining a viable aerobic microbe count at to employing a two-point calibration curve of tthreshold to TVC for each type of sample. One point on the calibration curve is the x-intercept value (i.e., an estimated or experimental value for the logarithm of the minimum viable aerobic microbe count at commencement of testing (to) in a sample effective for causing the sample to reach tThreshold substantially instantaneously upon commencement of incubation). The other point is ascertained experimentally from a sample having a smaller known viable aerobic microbe count at to. |
US08563260B2 |
Capillary for immunoassay, and capillary immunoassay method using same
A capillary for an immunoassay is provided which comprises an insoluble layer of an oxidase formed on an inner wall surface of said capillary, said oxidase being conjugated to a first antibody, and a layer of a hydrophilic polymer formed on said insoluble layer, said hydrophilic polymer layer containing a second antibody conjugated to a peroxidase, wherein said first and second antibodies are capable of binding to the same antigen. |
US08563259B2 |
Complement-mediated thrombophilic assay
A method for assessing the presence of an acquired thrombophilia disorder in a patient exhibiting hypercoagulation is disclosed. |
US08563255B2 |
Monoclonal antibody capable of binding integrin alpha 10 beta 1
The present invention provides a monoclonal antibody or a fragment thereof binding to the extracellular I-domain of integrin alpha10beta1 and a hybridoma cell line deposited at the Deutsche Sammlung von Microorganismen and Zellkulturen GmbH under the accession number DSM ACC2583. Furthermore, the present invention also provides a monoclonal antibody or a fragment thereof binding to the extracellular I-domain of integrin alpha10beta1 produced by the hybridoma cell line deposited. Methods and uses of said antibody or a fragment thereof in identifying and selecting cells of a chondrogenic nature for treatment purposes, in particular for the identification and isolation of chondrocytes, mesenchymal progenitor cells and embryonic stem cells for tissue engineering of cartilage, or for identifying diagnostic and therapeutic tools in studying the biological role and the structural/functional relationships of the integrin alpha10beta1 with its various extracellular matrix ligands are also included. |
US08563251B2 |
High-throughput methods for quantifying cells in environmental and laboratory samples
The invention provides compositions (e.g., kits) and methods for determine the number of bacteria and other microbes in samples having low concentrations of microbes, for use, e.g., in biological warfare defense, microbe detection and agricultural and environmental sciences. |
US08563250B2 |
Methods for identifying bioagents
The present invention provides methods for rapid forensic investigations by identification of bioagents associated with biowarfare and acts of terrorism or crime. The methods are also useful for epidemiological investigations by genotyping of bioagents. |
US08563246B2 |
Combinatorial decoding of random nucleic acid arrays
Methods disclosed herein relate to identification of nucleotides in a nucleotide sequence. |
US08563244B2 |
Microfluidic droplet queuing network
A multi-port liquid bridge (1) adds aqueous phase droplets (10) in an enveloping oil phase carrier liquid (11) to a draft channel (4, 6). A chamber (3) links four ports, and it is permanently full of oil (11) when in use. Oil phase is fed in a draft flow from an inlet port (4) and exits through a draft exit port (6) and a compensating flow port (7). The oil carrier and the sample droplets (3) (“aqueous phase”) flow through the inlet port (5) with an equivalent fluid flow subtracted through the compensating port (7). The ports of the bridge (1) are formed by the ends of capillaries held in position in plastics housings. The phases are density matched to create an environment where gravitational forces are negligible. This results in droplets (10) adopting spherical forms when suspended from capillary tube tips. Furthermore, the equality of mass flow is equal to the equality of volume flow. The phase of the inlet flow (from the droplet inlet port (5) and the draft inlet port (4) is used to determine the outlet port (6) flow phase. |
US08563242B2 |
Method for detecting chromosomal aneuploidy
The present invention relates to a new, non-invasive method for detecting chromosomal aneuploidy by analyzing a sample from a pregnant woman. The detection is based on the ratio between the amount of a fetal methylation marker located on a chromosome relevant to the aneuploidy and the amount of a fetal genetic marker located on a reference chromosome, offering improved accuracy. |
US08563241B2 |
Genetic predictors of international normalized ratio (INR) fluctuation with warfarin therapy
There are disclosed methods and kits for identifying a subject having genetic predictors of predisposition to abnormal international normalized ratio (INR) fluctuation during warfarin therapy. In an embodiment, a method includes testing the subject to check for a presence of a predetermined genetic variation. The predetermined genetic variation is correlated with abnormal INR fluctuation during warfarin therapy. The subject is identified as having a predisposition to abnormal INR fluctuation during warfarin therapy when the testing indicates the presence of the predetermined genetic variation. In one embodiment, a kit includes a test to check the subject for a presence of a predetermined genetic variation. The predetermined genetic variation is correlated with abnormal INR fluctuation during warfarin therapy. The kit includes an indicator to identify the presence of the predetermined genetic variation so as to identify the subject as having a predisposition to abnormal INR fluctuation during warfarin therapy. |
US08563237B2 |
Biopolymer resonant tunneling with a gate voltage source
The invention provides an apparatus and method for sequencing and identifying a biopolymer. The invention provides a first electrode, a second electrode, a first gate electrode, a second gate electrode, a gate voltage source and a potential means. The gate electrodes may be ramped by a voltage source to search and determine a resonance level between the first electrode, biopolymer and second electrode. The potential means that is in electrical connection with the first electrode and the second electrode is maintained at a fixed voltage. A method of biopolymer sequencing and identification is also disclosed. |
US08563236B2 |
Mutational profiles in HIV-1 reverse transcriptase correlated with phenotypic drug resistance
The invention provides novel mutations, mutation combinations or mutational profiles of HIV-1 reverse transcriptase and/or protease genes correlated with phenotypic resistance to HIV drugs. More particularly, the present invention relates to the use of genotypic characterization of a target population of HIV and the subsequent correlation of this information to phenotypic interpretation in order to correlate virus mutational profiles with drug resistance. The invention also relates to methods of utilizing the mutational profiles of the invention in databases, drug development, i.e., drug design, and drug modification, therapy and treatment design, clinical management and diagnostic analysis. |
US08563231B2 |
Patterning process and materials for lithography
Methods for forming a pattern in a lithography process for semiconductor wafer manufacturing are provided. In an example, a method includes forming a photoresist layer over a material layer; performing a first exposure process on the photoresist layer, thereby forming an exposed photoresist layer having soluble portions and unsoluble portions; treating the exposed photoresist layer, wherein the treating includes one of performing a second exposure process on the exposed photoresist layer and forming an adsorbing chemical layer over the exposed photoresist layer; and developing the exposed and treated photoresist layer to remove the soluble portions of the photoresist layer, wherein the unsoluble portions of the photoresist layer form a photoresist pattern that exposes portions of the material layer. |
US08563228B2 |
Methods of forming patterns on substrates
A method of forming a pattern on a substrate includes forming spaced first features over a substrate. The spaced first features have opposing lateral sidewalls. Material is formed onto the opposing lateral sidewalls of the spaced first features. That portion of such material which is received against each of the opposing lateral sidewalls is of different composition from composition of each of the opposing lateral sidewalls. At least one of such portion of the material and the spaced first features is densified to move the at least one laterally away from the other of the at least one to form a void space between each of the opposing lateral sidewalls and such portion of the material. |
US08563227B2 |
Method and system for exposure of a phase shift mask
The present disclosure provides a method of making a mask. The method includes providing a substrate having a first attenuating layer on the substrate and a first imaging layer on the first attenuating layer; performing a first exposure to the first imaging layer using a first radiation energy in writing mode; performing a first etching to the first attenuating layer; performing a second etching to the substrate; forming a second imaging layer on the first attenuating layer and the substrate; performing a second exposure to the second imaging layer using a light energy and another mask; and performing a third etching to the first attenuating layer after the second exposure. |
US08563221B2 |
Phototools having a protective layer
A phototool comprises an optically transparent substrate having designed pattern and a protective layer on the substrate. The protective layer comprises a cured hardcoat composition. The hardcoat composition comprises (i) one or more epoxy silane compounds (ii) one or more fluorochemical additives selected from the group consisting of perfluoropolyether-urethane silanes and silane-functionalized perfluoropolyether acrylate oligomers, and (iii) photo-acid generator. |
US08563220B2 |
High resolution, solvent resistant, thin elastomeric printing plates
The present invention relates to a printing element having at least one polymer layer which has photoimageable constituents and a chemically functionalized polymer to make the polymer layer either more hydrophobic or hydrophilic. In one embodiment, the printing element comprises two adjacent polymer layers on a substrate in which the photoimaged layer comprises a polymer chemically modified with hydrophobic fluoroalkyl side groups to provide differential wetting with hydrophilic inks. |
US08563215B2 |
Diazonaphthoquinonesulfonic acid bisphenol derivative useful in photo lithographic sub micron patterning and a process for preparation thereof
The present invention provides novel diazonaphthoquinonesulfonic acid bisphenol derivatives. More particularly, the present invention relates to photo restive coating comprising alkali-soluble resin, a photoactive compound and a surfactant. The photoresist film prepared has less then one micron. The photoactive compound is soluble or swellable in aqueous alkaline solutions and is diazonaphthoquinonesulfonic bisphenol esters of the general formula (A), wherein DNQ represents a 2-Diazo-1-naphthoquinone-4-sulfonyl, 2-Diazo-1-naphthoquinone-5-sulfonyl, 1-Diazo-2-naphthoquinone-4-sulfonyl groups and R1 R1 represents an alkyl, aryl and substituted aryl groups. The invention also provides a process for coating and imaging the light-sensitive composition. |
US08563212B2 |
Methods for producing photosensitive microparticles, non-aqueous dispersions thereof and articles prepared therewith
Described are non-aqueous dispersions of photosensitive polymeric microparticles, comprising: a) an organic continuous phase comprising an organic solvent; and b) photosensitive polymeric microparticles dispersed in the organic continuous phase. The microparticles comprise an at least partially polymerized component having integral surface and interior domains, wherein the surface domain comprises a polymeric material that is solubilized by the organic solvent, the interior domain comprises a polymeric material that is insoluble in the organic solvent, and the surface domain and/or interior domain is photosensitive. Also described are methods of producing such non-aqueous dispersions, curable film-forming compositions containing them, and photosensitive coated substrates. |
US08563211B2 |
Co-emulsification of insoluble compounds with toner resins
A process for making a latex emulsion suitable for use in a toner composition includes co-emulsifying a bio-based resin with an insoluble component, such as a pigment or wax, whereby the resin encapsulates the insoluble component. The resulting latex, including the insoluble component encapsulated in the resin, may then be utilized to form a toner. The insoluble component may thus be included in toner particles, which might otherwise be difficult to achieve, using emulsion aggregation processes. |
US08563210B2 |
Liquid electrophotographic ink concentrates and methods for preparing the same
A liquid electrophotographic ink concentrate includes non-volatile solids present in an amount ranging from about 20% to about 70% of the ink concentrate, the non-volatile solids including encapsulated pigment particles having a particle size ranging from about 500 nm to about 20 μm, and a viscosity modifier. The ink concentrate includes a balance of a liquid composition, the liquid composition including a carrier. The concentrate is dispersible in an ink vehicle to form a print-ready liquid electrophotographic ink having the non-volatile solids present in an amount ranging from about 0.5% to 5% of the print-ready liquid electrophotographic ink. |
US08563208B2 |
Electrostatic charge image developing toner and method of producing the same, electrostatic charge image developer, toner cartridge, process cartridge, and image forming device
A toner for developing an electrostatic charge image includes: an amorphous polyester resin; a crystalline polyester resin; and a releasing agent, an amount of the releasing agent in the toner being from 5 to 15% by weight; an amount of the releasing agent present at a surface of the toner being from 10 to 35% by weight; and the toner showing at least one endothermic peak in each of a temperature range from 45 to 60° C., a temperature range from 65 to 80° C., and a temperature range from 85 to 100° C. in a temperature-rise process of differential scanning calorimetry of the toner. |
US08563203B2 |
Electrophotographic photosensitive member and electrophotographic apparatus
An electrophotographic photosensitive member is configured such that the average value Hx_ave of the content of hydrogen atoms in a central portion area of a photoconductive layer in a cylindrically axial direction thereof, the content Hx of the hydrogen atoms at an arbitrary point in the central portion area, the average value Hy_ave of the content of the hydrogen atoms in an end area of the photoconductive layer in the cylindrically axial direction thereof, and the content Hy of the hydrogen atoms at an arbitrary point in the end area satisfy 10≦Hx_ave≦30, Hx |
US08563197B2 |
Methods, apparatus and computer program products for fabricating masks and semiconductor devices using model-based optical proximity effect correction and lithography-friendly layout
Design rules for circuit patterns of a semiconductor device are identified, and schematic layouts of the circuit patterns are generated according to the design rules. Lithography friendly layout (LFL) circuit patterns are generated from the schematic layouts. Target layout circuit patterns are generated from the LFL circuit patterns. Optical proximity effect correction (OPC) is performed on the target layout circuit patterns to generate OPC circuit patterns. A mask is fabricated from the OPC circuit patterns, and may be used fabricate a semiconductor device. |
US08563194B2 |
Electrolyte membrane for polymer electrolyte fuel cell and method of manufacturing the same
An electrolyte membrane (1) includes a base material layer (1) containing a hydrocarbon-based electrolyte as a main component, and a surface layer (5) laminated with the base material layer (1). The surface layer (5) is a layer containing, as a main component, a polymeric material having a hydroxyl group and a proton conductive group. The polymeric material that constitutes the surface layer (5) contains, for example, a first polymer having a hydroxyl group, and a second polymer having a proton conductive group. A matrix is formed by cross-linking the first polymer, and the second polymer can be held in the matrix. |
US08563193B2 |
Fuel cell system
A fuel cell system includes n fuel cell modules and a control device for controlling the power generation amount of each of the fuel cell modules. An m-th fuel cell module of the fuel cell system includes an m-th exhaust gas discharge channel for discharging an exhaust gas from the m-th fuel cell module, and an m-th exhaust gas supply channel branched from the m-th exhaust gas discharge channel, for supplying the exhaust gas from the m-th fuel cell module to an (m+1)-th fuel cell module for warming up the (m+1)-th fuel cell module. |
US08563187B2 |
Method and device for improving the service life of a fuel cell at transitions in operation
The subject of the present invention relates to a method and a protector for reducing degradation of fuel cell systems at transitions in operation, in particular at electrodes or catalysts in a combustion chamber of a stack of a PEM fuel cell system in startup and shutoff events of the fuel cell system. A switchable material delivery device is provided for varying a delivery of material to the fuel cell system, so that a transition from a first state of the fuel cell system to a second state of the fuel cell system can be initiated, such that a potential difference between different electrodes can be effected. At least one reducing mechanism is provided for reducing the potential difference between the different electrodes during the transition, in which the reducing mechanism includes at least one compensating device for an unequal gas distribution by reducing the proportions causing degradation, to reduce degradation. The compensation device includes at least one short-circuiting unit, with which the different electrodes can be short-circuited, in order to reduce the potential difference. |
US08563183B2 |
Integrated dry gasification fuel cell system for conversion of solid carbonaceous fuels
An integrated dry gas fuel cell (IDG-FC) is provided. The IDG-FC includes at least one solid oxide fuel cell having an anode, a cathode and an electrolyte membrane disposed between the anode and the cathode. The IDG-FC further includes a conversion bed, where carbon dioxide gas is provided to the conversion bed to convert carbon monoxide gas from the carbon dioxide gas. Solid carbonaceous fuel is provided to the conversion bed to promote the gas conversion. The carbon monoxide is provided as fuel to the anode, and air is supplied to the cathode to provide oxygen for oxidation of the carbon monoxide at the anode to generate electric power. This new process does not require water, and supplies the oxygen required for the oxidation reaction through an ionically selective solid oxide electrolyte membrane. |
US08563177B2 |
Galvanic element
A galvanic element, for example a battery or an accumulator, in particular a lithium-ion cell, includes a negative electrode, a positive electrode, and a separator lying between the negative electrode and the positive electrode. In order to increase the specific capacitance, the negative electrode includes at least one layer system, said layer system including at least two graphene layers and at least one polymer layer. A polymer layer lies between two graphene layers. |
US08563175B2 |
Nonaqueous electrolyte battery, active material, method for producing same, method for producing alkali titanate compound, and battery pack
According to one embodiment, a negative electrode active material for a nonaqueous electrolyte battery is provided. The active material includes a titanium oxide compound having a crystal structure of a monoclinic titanium dioxide and having a crystallite, the crystallite having a crystallite size of 5 to 25 nm when it is calculated by using the half width of the peak of a (110) plane obtained by a powder X-ray diffraction (XRD) method using a Cu—Kα ray. |
US08563174B2 |
Secondary battery material and synthesis method
A composite Li1+xMn2−x−yMyO4 cathode material stabilized by treatment with a second transition metal oxide phase that is highly suitable for use in high power and energy density Li-ion cells and batteries. A method for treating a Li1+xMn2−x−yMyO4 cathode material utilizing a dry mixing and firing process. |
US08563173B2 |
Li-ion battery with anode current collector coating
An electrochemical cell in one embodiment includes a negative electrode including a form of lithium, a positive electrode spaced apart from the negative electrode, an electrolyte, a separator positioned between the negative electrode and the positive electrode, and a current collector in the negative electrode, the current collector including a substrate material and a coating material on the surface of the substrate material, wherein the coating material does not include a form of lithium. |
US08563169B2 |
Self assembled multi-layer nanocomposite of graphene and metal oxide materials
Nanocomposite materials having at least two layers, each layer consisting of one metal oxide bonded to at least one graphene layer were developed. The nanocomposite materials will typically have many alternating layers of metal oxides and graphene layers, bonded in a sandwich type construction and will be incorporated into an electrochemical or energy storage device. |
US08563165B2 |
Assembled battery
The disclosure is directed to an assembled battery that includes a plurality of battery modules and unit cells. The unit cells of each battery module are electrically connected through a plurality of collars placed around a shaft member that secures the battery modules. The shaft member may also electrically connect the unit cells in some embodiments. In other embodiments, axial force from the securing shaft member deforms the collars to create the electrical connections. Alternative embodiments include engagement members secure the battery modules in order to eliminate the need for axial force from a shaft member to complete the assembled battery. |
US08563164B2 |
Cylindrical type alkaline storage battery
A cylindrical type alkaline storage battery includes a cylindrical container having electrical conductivity, and an electrode assembly contained in the container, the electrode assembly being a roll obtained by rolling up a positive electrode plate, a negative electrode plate and a separator together. Provided that the maximum diameter of the container is Dmax and that the number of turns of the positive electrode plate is N, the relationship N≧[0.5×Dmax−2.65] is fulfilled (where “[ ]” represents Gauss' notation). Where the battery is of AA size, for example, the number N of turns is four or more. Also, provided the circumferential position of the roll starting end of the positive electrode plate is a reference position, the angle θ measured from the circumferential position of the roll terminating end of the positive electrode plate to the reference position ranges from 180° to 270°. |
US08563163B2 |
Tool batteries
A battery housing of a tool battery has a hook accommodation chamber and a battery cell accommodation chamber defined therein. A hook is accommodated within the hook accommodation chamber and is operable to lock and unlock the tool battery against a tool body of a power tool. Battery cells are disposed within the battery cell accommodation chamber. The hook accommodation chamber and the battery cell accommodation chamber are partitioned from each other. |
US08563159B2 |
Structure and method for removing battery cell heat
An apparatus includes a thermal strap that connects a first terminal of a first battery cell and a second terminal of a second battery cell. The thermal strap has high thermal and electrical conductivity. A wall link connects the thermal strap to a wall having high thermal conductivity. The wall link includes a first portion having high thermal and electrical conductivity and a second portion having high thermal conductivity but low electrical conductivity. The second portion is located between the first portion and the wall. |
US08563153B2 |
Battery module having improved end plate
A battery module including a row of batteries; and end plates coupled to ends of the row of batteries, wherein the end plates include a reinforcing portion for increasing strength of the end plates. |
US08563151B2 |
Electric vehicle
An electric vehicle is provided with a cell voltage sensor (32) and a cell temperature sensor (31) which are mounted to each of a plurality of cells (21); a gas temperature sensor (33), a carbon monoxide gas sensor (34), and a hydrogen gas sensor (35) which are mounted to a chamber (27); a gas temperature sensor (36), a carbon monoxide gas sensor (37), and a hydrogen gas sensor (38) which are mounted to a gas exhaust passage (28); and an air-conditioning fan (17), a channel-switching damper (19), and a driving motor (42) which lowers a window glass (41). When battery state values detected by the sensors (31) to (38) exceed predetermined thresholds, a battery pack (20) is judged to be abnormal. Then, the channel-switching damper (19) and the air-conditioning fan (17) are started and the window glass (41) is lowered to ventilate the vehicle interior. This speedily exhausts smoke generated from a lithium ion battery. |
US08563146B1 |
Method and system for providing a magnetic recording pole having a dual sidewall angle
A method for fabricating a magnetic transducer having an air-bearing surface (ABS). An underlayer having a first and second regions and a bevel connecting these regions is provided. The first region is thicker and closer to the ABS than the second region. An intermediate layer conformal with the underlayer is provided. A hard mask layer having a top surface perpendicular to the ABS is formed on the intermediate layer. Part of the hard mask and intermediate layers are removed to provide a trench. The trench has a bottom surface and sidewalls having a first angle between the bottom surface and the intermediate layer and a second angle corresponding to the hard mask layer. A pole is provided in the trench. The pole has a pole tip, a yoke distal, and a bottom bevel. At least the yoke includes sidewalls having sidewall angles corresponding to the first and second angles. |
US08563144B2 |
Organic electroluminescence device and method for fabricating the same
An organic electroluminescent (EL) device is provided which uses an electron-transport layer including hole blocking capability. The device includes a stack structure, with an emitting layer and an electron-transport layer provided between an anode and a cathode. The electron-transport layer is a mixture of at least two materials. This mixture may include an organic compound and one or more other organic compounds, or may include a metal or inorganic compound and one or more other metal or inorganic compounds, or may include one or more organic compounds and one or more metal or inorganic compounds. By incorporating a hole blocking capability into the electron-transport layer, structure and fabrication of the device is simplified and efficiency is increased. |
US08563141B2 |
Carrier for manufacturing printed circuit board, method of manufacturing the same and method of manufacturing printed circuit board using the same
Disclosed is a carrier for manufacturing a printed circuit board, which includes a first carrier including a first binder having a first opening and a first metal layer formed in the first opening of the first binder, and a second carrier, stacked with the first carrier and including a second binder having a second opening and a second metal layer which is formed in the second opening of the second binder and which partially overlaps with the first metal layer, so that the carrier is simply configured and the binders are formed not only on the lateral surfaces of the metal layers but also on the upper surfaces thereof, thus improving the reliability of bonding of the carrier at the periphery. A method of manufacturing the carrier and a method of manufacturing a printed circuit board using the carrier are also provided. |
US08563140B2 |
Moisture resistant coating
Some embodiments of the invention generally relate to a moisture barrier coating that is biodegradable and compostable. Some embodiments also relate to a coating that is dual ovenable. Such coatings may be used to increase moisture resistance and provide non-stick or release characteristics when applied to biodegradable and compostable disposable food packaging and food service items. In some embodiments, a plasticizer, an amide wax and optionally a rosin are added to a cellulose-ester-based coating to increase moisture resistance. In other embodiments, a biodegradable polymer, an amide wax, optionally a plasticizer, and optionally a rosin are added to a cellulose-ester-based coating to drastically increase moisture resistance. In still other embodiments, phospholipids or medium-chain triglycerides or increased levels of amide wax may be added to the either of the embodiments above to provide enhanced release characteristics. |
US08563139B2 |
Non-hydrating plaster composition and method
A method of finishing an interior wall includes the steps of preparing a substrate of building panels comprising gypsum, cement or combinations thereof, said substrate having a surface, followed by applying a coating to the substrate, said coating comprising 5-20% by weight of a latex emulsion binder, 40-80% by weight calcium sulfate hemihydrate, 0.05-2% by weight of a set preventer and 20-60% by weight water. |
US08563136B2 |
Carbon nanotube composite material and method for making the same
A method for manufacturing a carbon nanotube includes following steps. A carbon nanotube structure comprising of a plurality of carbon nanotubes is provided. Metal is applied to outer surfaces of the carbon nanotubes. The carbon nanotube structure is heated in vacuum to a first temperature and a second temperature greater than the first temperature. At the first temperature, there is a reaction between the carbon nanotubes and the metal layer to form metal carbide particles. At the second temperature, the carbon nanotube structure breaks having at least one tip portion. |
US08563135B2 |
Mesostructured aluminosilicate material made of spherical particles of specific size
A mesostructured aluminosilicate material is described, which consists of at least two elementary spherical particles, each one of said spherical particles consisting of a matrix based on silicon oxide and aluminium oxide, said matrix having a pore diameter ranging between 1.5 and 30 nm, a Si/Al molar ratio at least equal to 1 and amorphous walls of thickness ranging between 1 and 30 nm, said elementary spherical particles having a diameter D such that 10 |
US08563134B2 |
Usage of copolymerisates as additives for lacquers
Finely distributed copolymer waxes, which are in particular suitable as additives for lacquers, produced by a) reacting long-chained olefin hydrocarbons with chain lengths being greater than or equal to 28 C-atoms with unsaturated polycarboxylic acids or the anhydrides thereof in the presence of at least one radical initiator and b) subsequent micronization by milling or spraying, characterized in that the particles of the milled or sprayed copolymer waxes are less than 50 μm, preferably less than 40 μm, particularly preferably less than 30 μm 98 to 99 are preferred, 5% of the particles, in particular 99.5 to 100% of the particles less than 50 μm, preferably less than 40 μm, particularly preferably less than 30 μm. |
US08563133B2 |
Compositions and methods for modulation of nanostructure energy levels
Ligand compositions for use in preparing discrete coated nanostructures are provided, as well as the coated nanostructures themselves and devices incorporating same. Methods for post-deposition shell formation on a nanostructure, for reversibly modifying nanostructures, and for manipulating the electronic properties of nanostructures are also provided. The ligands and coated nanostructures of the present invention are particularly useful for close packed nanostructure compositions, which can have improved quantum confinement and/or reduced cross-talk between nanostructures. Ligands of the present invention are also useful for manipulating the electronic properties of nanostructure compositions (e.g., by modulating energy levels, creating internal bias fields, reducing charge transfer or leakage, etc.). |
US08563132B2 |
Glass fiber-treating agent and glass fiber-treating composition
Glass fiber-treating agent which includes: (A) 5-95% by weight of an acetylene glycol or an ethylene oxide and/or a propylene oxide adduct of an acetylene glycol; and (B) 5-95% by weight of a silicone surfactant which may be polyoxyalkylene-modified. The glass fiber-treating agent reduces dynamic and static surface tension and contact angle. The glass fiber-treating agent provides excellent wetting, penetration, and antifoaming properties when glass fibers are treated therewith. |
US08563131B2 |
Flexible poly(arylene ether) composition and articles thereof
A thermoplastic composition comprises poly(arylene ether) having an initial intrinsic viscosity greater than 0.25 dl/g as measured in chloroform at 25° C.; a polyolefin having a melt temperature greater than or equal to 120° C. and a melt flow rate of 0.3 to 15; a first block copolymer having a aryl alkylene content greater than or equal to 50 weight percent based on the total weight of the first block copolymer; a second block copolymer having an aryl alkylene content less than 50 weight percent based on the total weight of the second block copolymer; and a flame retardant, wherein the poly(arylene ether) is present in an amount greater than the amount of polyolefin. The composition is useful in the production of covered wire. |
US08563129B2 |
Polysilazane-containing coatings for increasing the conversion efficiency of encapsulated solar cells
The invention relates polysilazane-containing coatings for increasing the light permeability of sun-facing covers of solar cells. The coating for surfaces contains at least one polysilazane of formula (1) —(SiRR′R″—NR′″1)n- (1), wherein R′, R″, R′″ are the same or different or represent an optionally substituted alkyl, aryl, vinyl or (trialkoxysilyl)alkyl group, n being an integer and n being chosen in such a manner that the perhydropolysilazane has a number average molecular weight of 150 to 150,000 g/mol, a solvent and a catalyst. The cured coating has a thickness of at least 0.50-10 micrometer, preferably 0.2 to 5 micrometer, especially preferred 0.5 to 1.5 micrometer. It is especially suitable as transmission-promoting coating for use in sun-facing covers of solar cells. |
US08563127B2 |
Absorbent composite material and bodily fluid-absorbing article comprising water-absorbent resin particles having specific surface strength
An absorbent composite comprising: a base material and water-absorbent resin particles; wherein the following conditions (1) to (4) are fulfilled: (1) the weight ratio of water-absorbent resin relative to the total weight of the base material and water-absorbent resin is 65 to 99 wt %, (2) the water-absorbent resin particles adhering directly to the base material constitute 50 wt % or more of the total water-absorbent resin particles; (3) the average absorption capacity of the water-absorbent resin particles is 50 g/g or more; and (4) the amount of residual monomers in the water-absorbent resin is 200 ppm or less. |
US08563126B2 |
Film for packaging product, especially an envelope
The invention relates to a film 2 including at least one print layer 3 and a non-woven layer 4 having a density of less than 0.5 g/cm3.The invention also relates to a packaging product, especially an envelope, including such a film, and to a method for obtaining an above-described film, in which the film 2 is obtained by assembling, for example by extrusion-laminating or by laminating, a print layer and a non-woven layer. |
US08563114B2 |
Industrial fabric comprised of selectively slit and embossed film
A nonwoven industrial fabric, and a method of constructing the fabric. The fabric comprises at least one layer of a polymeric film having a plurality of apertures extending from an upper surface through to a lower surface. Adjacent pairs of the apertures define land areas therebetween, and selected land areas comprise protrusions extending from at least one of the upper surface and the lower surface of the layer to form a profile to the respective surface. The method comprises optionally pre-embossing the film, cutting the film to provide the plurality of apertures, applying pressure to selected land areas to form the protrusions to create a contoured profile, and treating the film to set the contoured profile. Additional surface treatment can be provided, and two or more layers can be secured over each other for multilayer fabrics. The invention provides a simplified and economical construction, while maintaining stability and strength. |
US08563112B2 |
Organic EL light-emitting device and method for manufacturing the organic EL light-emitting device
This invention provides an organic EL light-emitting device, which can prevent the occurrence of brightness unevenness due to resistance of a transparent electrode, in a large surface light-emitting panel of an organic EL element.The organic EL light-emitting device includes an element formation substrate 1, on which an organic EL element 2 including an organic light-emitting layer is stacked, and a sealing substrate 3 for sealing the organic EL element so as to accommodate the organic EL element between the element formation substrate and the sealing substrate. A sealing portion 4 formed of an adhesive is formed in the peripheral edge portion between the element formation substrate 1 and the sealing substrate 3, and a grease layer 5 or a gel layer 5 is accommodated in between the element formation substrate, on which the organic EL element surrounded by the sealing portion is formed, and the plate-shaped sealing substrate so as to adhere to the element formation substrate and the sealing substrate. The grease layer 5 or the gel layer 5 contains an oligomer or a polymer having organosiloxane bond (—R2SiO—) or fluorinated polyether (—CF2CFYO—) as a skeleton. |
US08563103B2 |
Polylactide hydrosol and articles made therefrom
A polylactide hydrosol polymer formulations suitable for thin film articles and methods of making the thin film articles are provided. The formulations and methods can be use to make articles such as gloves, condoms, catheters and the like using dip forming, and various casting processes. |
US08563102B2 |
Resin blend of ethylene alpha olefin interpolymer and heterogeneous interpolymer for liquid packaging films
This invention relates to bags and pouches made from films for packaging of flowable materials, in particular liquids that are made from blends of polyethylene and polypropylene useful to in addition to possessing good flex crack resistance, these films can withstand steam sterilization and/or aseptic packaging conditions as they have Hot Tack Initiation Temperatures in the range of from about 100° C. to about 140° C. and Hot Tack Strengths of not more than 5 N/inch in the temperature range from 100° C. to 150° C. |
US08563100B1 |
Wall covering
A wall covering includes a composite structure that includes a first layer forming a non-image side of the composite structure and a second layer laminated to the first layer forming an image side of the composite structure. The first layer includes a fabric to facilitate air flow on the non-image side. The image side has a surface roughness of less than or equal to 5 microns by PPS method. The second layer includes one of synthetic polymeric fiber in a non-woven structure and a synthetic polymeric film. The wall covering is a Type-II wall covering that is PVC-free. |
US08563098B2 |
Pneumatic object provided with a gastight layer containing a thermoplastic elastomer and a platy filler
An inflatable article is provided with a layer impermeable to inflation gases. The layer has an elastomer composition that includes at least, as a predominant elastomer by weight, a thermoplastic styrene (TPS) elastomer and a platy filler. The platy filler has an equivalent diameter (Dv (0.5)) of between 20 and 45 micrometers, and has a shape factor (F) greater than 65. |
US08563097B2 |
Remote combustion deposition burner and/or related methods
Certain example embodiments relate to a burner for use in combustion deposition depositing a coating on a substrate. An infrared (IR) burner generates radiant energy in an area between the burner and the substrate. A delivery device (1) provides a stream comprising a substantially vaporized precursor and a carrier gas from a location remote from the radiant energy generated by the IR burner, and (2) causes the stream to flow between the substrate and the IR burner. The stream is substantially laminar when exiting the delivery device. The radiant energy is sufficient to cause the precursor in the stream to be combusted and to heat the substrate to allow at least a portion of the combusted precursor to form the coating, directly or indirectly, on the substrate. The burners of certain example embodiments may be used, for example, to combustion deposition deposit metal oxide coatings onto glass substrates. |
US08563094B2 |
Method for producing a component with a nanostructured coating
In a method for producing a component (20) with a coating (24) containing nanoparticles (21), it is provided that, in order to introduce the nanoparticles (21) into the coating (24), a film (19) with the dispersely distributed nanoparticles (21) is applied to the surface (22) to be coated, which decomposes with incorporation of the nanoparticles (21) during the actual coating operation and is thereby not incorporated into the layer. |
US08563092B2 |
Formation of palladium sulfide
Technologies are generally described for methods and systems of forming a palladium sulfide film on a substrate including flexible substrate. A palladium sulfide precursor may be applied to the substrate. The palladium sulfide precursor may comprise a palladium organothiolate. The palladium sulfide precursor may be heated under reaction conditions sufficient to decompose the palladium sulfide precursor to form the palladium sulfide film or patterns, the latter using various lithography techniques. |
US08563082B2 |
Method for producing a cross-linked substance, especially in the form of a microcapsule or layer
A device for producing a crosslinked substance, e.g., of crosslinked microcapsules (1) of a crosslinkable capsule substance, in particular crosslinked alginates, is described, having a first dispensing device (2) for dispensing a jet of the crosslinkable capsule substance and a crosslinking device for applying a crosslinking agent to the capsule substance, whereby the crosslinking device has a second dispensing device (5) which directs a jet (9, 13) of the crosslinking agent at the jet or at a layer of the capsule substance. |
US08563078B2 |
Method of fabricating a painted substrate that is electrically non-conductive
The present invention relates to a method of fabricating a painted substrate (30) using powder paint (21). The substrate is electrically insulating. The method includes the following steps performed in succession: a) a treatment coating (10) is placed on a mold (1), the treatment coating (10) includes at least one preparation layer having a release agent (15, 15′) in contact with the mold (1); b) the treatment coating (10) is electrostatically covered with powder paint (21) in such a manner that the powder paint (21) is attracted towards the mold (1) and is held against the treatment coating (10); c) the powder paint (21) is transformed at least in part in order to obtain a layer (20) of powder paint (21); and d) the substrate (30) is prepared on the layer (20) of powder paint to form the painted substrate. |
US08563075B2 |
Removal of non-conductive hydrophilic coatings from lands of fuel cell bipolar plates
A bipolar plate for a fuel cell is provided including a plate having an active surface with a plurality of flow channels formed therein. The plurality of flow channels have a hydrophilic coating deposited thereon and define a plurality of lands disposed therebetween. The plurality of lands is substantially free of the hydrophilic coating. Furthermore, a thickness of the hydrophilic coating is substantially constant along a length of the active surface and an edge of the hydrophilic coating adjacent the plurality of lands is substantially continuous. A method for preparing the bipolar plate is also provided. |
US08563074B2 |
Confectionery compositions
A chocolate composition wherein at least 30% by weight, e.g. 33 to 40% or more, of the sucrose content of regular chocolate is replaced by a combination of dietary fibres and wherein the fibre combination comprises, consists of or consists essentially of a dextrin, an inulin and an oligofructose. |
US08563071B2 |
Production of soluble protein solutions from soy (“S701” CIP)
A soy protein product, which may be an isolate, produces transparent heat-stable solutions at low pH values and is useful for the fortification of soft drinks and sports drinks without precipitation of protein. The soy protein product is obtained by extracting a soy protein source material with an aqueous calcium salt solution to form an aqueous soy protein solution, separating the aqueous soy protein solution from residual soy protein source, adjusting the pH of the aqueous soy protein solution to a pH of about 1.5 to about 4.4 to produce an acidified clear soy protein solution, which may be dried, following optional concentration and diafiltration, to provide the soy protein product. |
US08563063B2 |
Melon peeler systems
A melon peeler system designed to safely and quickly separate the rind from a melon for consumption. The melon peeler system includes a melon peeler assembly having a concave base, a horizontal blade, fasteners, and vertical supports. The concave base has a smooth surface and serves as a melon cutting guide. The horizontal blade is supported a user-determined distance above the concave base by the vertical supports and the blade is a small, flat cutting edge sufficiently sharp to slice through a melon but not sufficiently sharp to easily cut a user. Suction cups fasteners located on the bottom of the device provide stability and allow the assembly to be removably affixed to a planar surface of the user's choice. |
US08563062B2 |
Reduction of sorbic acid precipitation by volume control
A method for reducing sorbic acid precipitation in a volume of stable preserved syrup. A sorbate is dissolved in fluid having a temperature between about 150° F. and about 200° F. and is added to an agitated volume of bulk fluid having a temperature between about 150° F. and about 200° F. to form a sorbate-containing volume of fluid having a volume of at least 90 volume percent of the syrup volume. Acid is dissolved in fluid at a temperature of between about 150° F. to about 200° F. and added to the sorbate-containing volume to form the volume of stable preserved syrup. |
US08563058B2 |
Capsule with filter for preparing a liquid nutritional or food composition and related beverage production system
A capsule for use in a beverage production device, the capsule containing ingredients to produce a nutritional or food liquid when a liquid is fed into the capsule at an inlet face thereof, with the capsule being provided with a filter having a plurality of filtering orifices and a flow collection member placed downstream of the filter to collect the filtered liquid from the filtering orifices. The collection member includes at least one restriction orifice to focus the flow of liquid in at least one jet of liquid at high velocity in the compartment containing the ingredients. The invention is particularly advantageous for producing a nutritional liquid (e.g., infant formula) or a food from powdered ingredients. |
US08563053B2 |
Compositions and methods of natural products in nanoformulations for the prevention and treatment of osteoporosis
A composition and method for treating a bone condition of an animal. The composition includes a nanoformulation of active ingredients. The active ingredients include Lepidium Sativum or other Lepidium extracts, calcium, vitamin D, and antioxidants. The method for treating a bone condition includes introducing the composition into the animal. |
US08563052B2 |
Method for preparing gintonin, which is a novel glycolipoproetin from panax ginseng, and gintonin, which is a novel glycolipoprotein, prepared by the method
Disclosed are the novel glycolipoprotein gintonin isolated and identified from ginseng, a method for preparing the same, and uses thereof. Gintonin causes a transient increase in intracellular free Ca2+ level, which in turn activates endogenous Ca2+-activated chloride channel to elevate intracellular calcium levels. Therefore, the novel glycolipoproteins are useful in the therapy and prophylaxis of calcium deficiency-associated diseases as well as effectively inducing calcium-dependent physiological activities, including adaptogenic activity, immunostimulatory activity, aphrodisiac activity, neuroprotection and neuroactivation, angiogenesis, and antidiabetic activity. |
US08563051B2 |
Herbal composition for weight management
Herbal extracts composition suitable for weight management in mammals is disclosed. The composition comprises a mixture of Garcinia extract, Green tea extract, Green coffee extract and Banaba extract. The method of reducing weight, and treating diabetes in mammals involve oral administration of the composition. The invention further relates to a method of producing and standardizing the individual extract useful for human health. |
US08563043B2 |
Innately multimodal nanoparticles
A gold-coated iron oxide nanoparticle, method of making thereof, and method of using thereof is disclosed. The nanoparticle is substantially toxin free (making it clinically applicable), easily functionalized, and can serve as a contrast agent for a number of imaging techniques, including imaging a subject in at least two distinct imaging modes. Further, the nanoparticle is well-suited for therapeutic uses. |
US08563042B2 |
Pharmaceutical composition containing fenofibrate and method for the preparation thereof
The invention concerns a pharmaceutical composition containing micronized fenofibrate, a surfactant and a binding cellulose derivative, as solubilizing adjuvant, preferably hydroxypropylmethylcellulose. The cellulose derivative represents less than 20 wt. % of the composition. The association of micronized fenofibrate with a binding cellulose derivative, as solubilizing adjuvant and a surfactant enables enhanced bioavailability of the active principle. The invention also concerns a method for preparing said composition without using any organic solvent. |
US08563035B2 |
Oral tablet compositions of dexlansoprazole
Oral tablet compositions of dexlansoprazole or pharmaceutically acceptable salts or hydrated forms thereof having a gradual release and processes for the manufacture of the tablet composition and its use in the treatment of gastrointestinal disorders. |
US08563034B2 |
Dual release oral tablet compositions of dexlansoprazole
Dual release oral tablet compositions of dexlansoprazole or pharmaceutically acceptable salts or hydrated forms thereof and processes for the manufacture of the tablet composition and its use in the treatment of gastrointestinal disorders. |
US08563031B2 |
Piroxicam-containing matrix patches and methods for the topical treatment of acute and chronic pain and inflammation therewith
This invention relates to matrix patches for the topical (i.e., transdermal) delivery of piroxicam and methods for the treatment of acute and chronic pain and inflammation therewith, particularly pain and inflammation caused by sports injuries or other muscle aches or injuries requiring the application of analgesic and/or anti-inflammation medication, in this instance, piroxicam. |
US08563024B2 |
Biodegradable material components
A biodegradable material for use in making items usable in surgery and related fields of medicine. The material comprising a bioabsorbable thermoplastic polymer component and a bioactive filler material. In components made of the material particles of the filler material occur embedded within the surface of the components. |
US08563021B2 |
Methods employing anhydrous disinfectant
Use of dried compositions of silver dihydrogen citrate along with citric acid in antimicrobial amounts directly as disinfectants is described. |
US08563018B2 |
Foamable pesticide compositions
Ready-to-use foamable pesticide compositions that contain a particulate pesticide suspended therein and applicators for dispensing such compositions. Methods for treating pests such as arthropods by contacting pests with such compositions are also provided. |
US08563016B2 |
Lamellar oil-in-glycol gel compositions and the process of preparation
The present invention is directed to a lamellar oil-in-glycol gel comprising (a) at least one glycol, (b) at least one fatty alcohol, (c) at least one cationic surfactant and optionally (d) at least one benefit agent, said lamellar gel capable of providing enhanced mass and promoting the permeation of the benefit agent through a keratinous substrate such as the skin, hair and fingernails, providing both deep and superficial treatment thereof. |
US08563014B2 |
Modafinil oral lyophilizate
The invention concerns an oral lyophilizate comprising modafinil particles having a median diameter of about 10 to about 1000 μm in association with an appropriate amount of at least one excipient selected from the group consisting of fatty acid esters of glycerol, cyclic oligosaccharides, sweeteners or mixtures thereof. |
US08563012B2 |
Compositions and methods for administering compartmentalized frozen particles
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue. |
US08563011B2 |
Use of low molecular weight amino alcohols in ophthalmic compositions
The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives. |
US08563004B2 |
Yersinia spp. polypeptides and methods of use
The present invention provides isolated polypeptides isolatable from a Yersinia spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. |
US08563003B2 |
Method for the treatment of malignant and infectious chronic diseases
The present invention relates to methods of treatment useful in chronic diseases, by means of the rupture of tolerance to self-antigens and increasing autoimmune response against these antigens. More particularly, the present invention relates to methods useful in the treatment of tumors that are growth dependent on the Epidermal Growth Factor, including non-small cell lung carcinoma.In the present invention a therapeutic combination is revealed that includes the combination of a vaccine against self antigens with a monoclonal antibody against peripheral T cells or a chemotherapeutic drug able to induce a depletion of peripheral T cells.In another one of its aspects the present invention reveals a method of treatment of chronic diseases in which the rupture of the tolerance to self antigens is essential for the control of the disease, this method includes the administration of a immune suppressor agent between two cycles of vaccination against a self antigen, which could be for example the EGF, being this scheme of effective treatment for the reduction of tumors whose growth depends on EGF. |
US08563001B2 |
Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (BHS) disease
A number of β-hemolytic streptococci polynucleotides and polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, are described. Two or more of the polypeptides of the invention can be formulated for use as immunogenic compositions. Also disclosed are methods for immunizing against and reducing infection caused by β-hemolytic streptococci. |
US08562998B2 |
Targeting of antigen presenting cells with immunonanotherapeutics
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising nanocarriers. The present invention provides methods of designing, manufacturing, and using nanocarriers and pharmaceutical compositions thereof. |
US08562996B2 |
RSV-specific binding molecules and means for producing them
The invention provides antibodies and functional equivalents thereof which are capable of specifically binding RSV, and means and methods for producing them. |
US08562995B2 |
Neoplasm specific antibodies and uses thereof
The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms. |
US08562993B2 |
Methods for treating GI syndrome and graft versus host disease
We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases. |
US08562988B2 |
Strategies for improved cancer vaccines
The present invention concerns methods and compositions for forming anti-cancer vaccine complexes. In preferred embodiments, the anti-cancer vaccine complex comprises an antibody moiety that binds to dendritic cells, such as an anti-CD74 antibody or antigen-binding fragment thereof, attached to an AD (anchoring domain) moiety and a xenoantigen, such as CD20, attached to a DDD (dimerization and docking domain) moiety, wherein two copies of the DDD moiety form a dimer that binds to the AD moiety, resulting in the formation of the vaccine complex. The anti-cancer vaccine complex is capable of inducing an immune response against xenoantigen expressing cancer cells, such as CD138negCD20+ MM stem cells, and inducing apoptosis of and inhibiting the growth of or eliminating the cancer cells. |
US08562986B2 |
Engineered anti-alpha V-integrin hybrid antibodies
The invention relates to engineered antibodies which specifically bind to integrin receptors, especially the alpha V integrin receptor subunit. The antibodies comprise the antigen binding sites (CDRs) of a known mouse anti-integrin antibody, as well as hybrid light chain variable sequences, mutated heavy chain variable sequences (Frs) and modified heavy chain constant sequences. The novel antibodies have improved immunogenic and expression properties and elicit excellent anti-angiogenic as well as anti-tumor activities in humans in monotherapy but also and above all in combination with other angiogenesis and tumor inhibiting agents. |
US08562978B2 |
Stable digestive enzyme compositions
Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing. |
US08562977B2 |
Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis
Pharmaceutical compositions comprising truncated tryptophanyl-tRNA synthetase polypeptides useful for regulating angiogenesis an nucleic acids encoding such tRNA synthetase polypeptides are described. Methods of making and using such compositions are also disclosed. |
US08562974B2 |
Method for expanding Cd4+ Cd25+ T regulator cells
A method for generating/expanding in vitro a CD4+CD25+ T regulatory (Tr) cell and the use thereof in the treatment of diseases associated with a cell-mediated immune response (including T- and antibody-mediated responses). |
US08562968B2 |
Use of stem cells and CD6 depleted stem cells for the induction of tolerance to allogenic transplants and/or for the treatment of leukemia
The present invention relates to the use of a composition containing stem cells as well as CD6 depleted stem cells for the induction of a tolerance to allogenic transplants and/or for the treatment of blood, immune, and cancer diseases for time-staggered application wherein first the stem cells are applied followed by application of the CD6 depleted stem cells. Furthermore, the present invention relates to a compound preparation containing stem cells and CD6 depleted stem cells. |
US08562965B2 |
Polymer derivatives comprising an acetal or ketal branching point
The invention provides a polymer comprising (i) a first water-soluble polymer segment that is covalently attached, either directly or through one or more atoms, to a first oxygen atom that is covalently attached to a linking carbon atom; (ii) a second water-soluble polymer segment is covalently attached, either directly or through one or more atoms, to a second oxygen atom that is covalently attached to the linking carbon atom; and (iii) a reactive group that is covalently attached, either directly or through one or more atoms, to the linking carbon atom. The invention also provides, among other things, methods for preparing polymers, conjugates, pharmaceutical compositions and the like. |
US08562959B2 |
Film foaming hydroalcoholic foam
The present invention provides a foam composition comprising an active agent. In particular, the foam composition produces a water resistant, preferably very water resistant, film upon application. |
US08562957B2 |
Oily hair cosmetics
Conventional hair cosmetic materials have difficulty in achieving both high improvement effects on damaged hair and excellent sensation upon use. The present invention provides an oil-based hair cosmetic material to realize hair cosmetics having both high improvement effects on damaged hair and excellent sensation upon use, and a production method of the same.The oil-based hair cosmetic material of the invention is those which comprise (A) a dibasic acid ester compound of general formula (1): wherein R1 is an alkylene group having a carbon number of 2-4, which may be mono- or poly-substituted, R2 and R3 are, independently of one another, an alkyl group having a carbon number of 1-4, which may be mono- or poly-substituted, R4 and R5 are, independently of one another, hydrogen or a methyl group or ethyl group which may be mono- or poly-substituted, m and n are, independently of one another, an integer of 0-4 with m+n≧1 (provided that the cases wherein R2 and R3 are both an ethyl group and m and n are both 1 are excluded), and (B) one or more oil agents selected from the group consisting of a volatile oil, an ester oil, a hydrocarbon oil, an animal/plant oil, and a silicone oil. Using this, it is possible to realize hair cosmetic materials and hair cosmetics that have both high improvement effects on damaged hair and excellent sensation upon use. |
US08562954B2 |
Dental compositions with sensitivity relief
A one-component prescription fluoride treatment composition having both fluoride efficacy and sensitivity relief is disclosed. The composition includes at least one metal fluoride and a nerve desensitizing agent such as potassium nitrate. The invention further includes a composition having at least one metal fluoride less than about 1.15% by weight of at least one metal fluoride; less than about 5 percent by weight of at least one alkali metal salt having desensitizing effect; at least one carrier; and at least one foaming agent that has thickening property. The composition may be formulated into a gel, a paste or any other convenient form, some of which contain abrasives. |
US08562950B2 |
GABA biomarkers for depression
Differential expression of nucleic acids in the brains of subjects suffering from late-onset depression has been demonstrated. The invention provides methods useful in the determination of late-onset depression. Also provided by the present invention is a screening method for the identification of compounds for treatment, prevention or diagnosis of late-onset depression. |
US08562944B2 |
PAA nanoparticles for enhancement of tumor imaging
A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and an imaging agent and methods for making and using same. |
US08562940B2 |
Process for preparing an alumina with controlled mesoporosity
A process for preparing a mesoporous alumina is described, comprising the following steps: a) mixing, in aqueous solution, at least one source of aluminum constituted by an aluminum alkoxide, at least one cationic surfactant and at least one organic solvent selected from methanol and ethanol; b) hydrothermally treating the mixture formed in said step a); c) drying the solid formed in said step b); d) calcining the solid formed in said step c). |
US08562937B2 |
Production of carbon nanotubes
A method and apparatus for manufacture of carbon nanotubes, in which a substrate is contacted with a hydrocarbonaceous feedstock containing a catalytically effective metal to deposit the feedstock on the substrate, followed by oxidation of the deposited feedstock to remove hydrocarbonaceous and carbonaceous components from the substrate, while retaining the catalytically effective metal thereon, and contacting of the substrate having retained catalytically effective metal thereon with a carbon source material to grow carbon nanotubes on the substrate. The manufacture can be carried out with a petroleum feedstock such as an oil refining atmospheric tower residue, to produce carbon nanotubes in high volume at low cost. Also disclosed is a composite including porous material having single-walled carbon nanotubes in pores thereof. |
US08562936B2 |
Carbon nanotube array structure and method for making the same
The present disclosure relates to a carbon nanotube array structure and a method for making the same. The carbon nanotube array structure includes a bendable flexible substrate and a carbon nanotube array. The flexible substrate has at least one surface. The carbon nanotube array is grown on at least one surface of the flexible substrate. In the method for making the carbon nanotube array structure, a reacting chamber, and a bendable flexible substrate with at least one surface are provided. The flexible substrate is disposed in the reacting chamber and heated to a certain temperature. A carbon source gas is supplied into the reacting chamber, thereby forming a carbon nanotube array on the catalyst layer. |
US08562928B2 |
Process for producing hydrogen, sulfur and sulfur dioxide from hydrogen sulfide-containing gas streams
A process for making molecular hydrogen, elemental sulfur and sulfur dioxide from hydrogen sulfide. The process involves contacting a gas stream of hydrogen sulfide within a contacting zone with a contacting composition comprising metal sulfide in a lower sulfided state and yielding from the contacting zone a product gas stream comprising hydrogen and a recovered contacting composition comprising metal sulfide in a higher sulfided state. The higher metal sulfide is regenerated with oxygen to yield elemental sulfur and sulfur dioxide. |
US08562926B2 |
Method and device for catchment of platinum group metals in a gas stream
A method and device for catchment of platinum group metals (PGM) in a gaseous steam, where the method comprises using a catalyst comprising a porous ceramic body in which at least a part of the surface area is covered by one or more PGM-catching metal(s)/alloy(s), and where the device comprises the porous ceramic body in which at least a part of the surface area is covered by one or more PGM-catching metal(s)/alloy(s). In a further aspect, the invention also relates to a method for producing the inventive device. |
US08562923B1 |
Process for obtaining pure litharge from lead acid battery paste
The present invention relates to the recovery of high purity litharge from spent lead acid battery paste at a low temperature which does not produce sulfur dioxide. In the process lead acetate is produced which is converted to pure litharge. |
US08562920B2 |
Micro plate treating device and micro plate treating method
An object is to provide a micro plate treating device and micro plate treating method capable of handling a larger number of kinds of solution or suspensions or a larger volume of solutions or suspensions per work area by use of a normalized micro plate without enlarging the scale of the device.The micro plate treating device comprises a micro plate having wells arranged in a matrix form, one or two or more nozzle heads each having nozzles capable of sucking and discharging a fluid and arranged in a matrix form, and moving means capable of moving relatively an interval between the micro plate and the nozzle heads, wherein tips of all the nozzles are configured to be permitted to be simultaneously inserted into some of the wells in the micro plate, at least one of the row interval or the column interval of the nozzles is set to a natural number multiple of the row interval or the column interval of the corresponding wells, the natural number being two or more, and at least one of the row number or the column number of all the corresponding nozzles is one to the natural number of the row number or the column number of the wells. |
US08562917B2 |
Analyte meter sleeves and methods
In some aspects, an analyte meter sleeve is provided for storing an analyte meter (e.g., a blood glucose meter or insulin pump) and a lancet device. The sleeve includes a first sleeve member adapted to receive the analyte meter and a second member affixed to the sleeve and adapted to receive the lancet device. The first sleeve member may have a window adapted to allow viewing of a meter display. Numerous other aspects are provided. |
US08562913B2 |
Air filtration and purification system
A system for filtering and purifying air within a closed environment. Air is drawn through a sequence of six filtration and purification stages, comprising, in order, an electrostatic prefilter to remove airborne impurities >=3 microns, an ultraviolet light source, a catalytic surface effective for breaking down hydrocarbons, a HEPA or other particulate filter for mechanically capturing airborne particles, a gas absorption filtration medium for removing volatile organic compounds and comprised primarily of activated charcoal, and an ionization module. The UV light is directed both upstream and downstream. The catalytic surface is semitransparent to UV light so that UV light strikes and kills microbes in the HEPA or other particulate filter medium. |
US08562912B2 |
Portable biochemical testing apparatus and operating method thereof
A portable biochemical testing apparatus and operating method thereof are disclosed. The portable biochemical testing apparatus includes a light source module, a sample module, a photoconductive material layer, a touch module, and a control module. At least one sample is disposed in the sample module. The photoconductive material layer is disposed between the sample module and the light source module. The touch module generates a driving signal according to a touch action of the user to drive the light source module to emit a light. When the light is emitted to the photoconductive material layer, the photoconductive material layer will generate a photoelectric driving effect. The at least one sample is affected by the photoelectric driving effect and generates a change corresponding to the touch action. |
US08562905B2 |
Multifunctional nanocomposites of carbon nanotubes and nanoparticles formed via vacuum filtration
In one aspect, the present invention provides a method of forming a film of nanocomposites of carbon nanotubes (CNTs) and platinum (Pt) nanoparticles. In one embodiment, the method includes the steps of (a) providing a first solution that contains a plurality of CNTs, (b) providing a second solution that contains a plurality of Pt nanoparticles, (c) combining the first solution and the second solution to form a third solution, and (d) filtering the third solution through a nanoporous membrane using vacuum filtration to obtain a film of nanocomposites of CNTs and Pt nanoparticles. |
US08562896B2 |
Micropattern transfer method and micropattern transfer device
An object of the present invention is to provide a micropattern transfer method and a micropattern transfer device in which the small amount of resin is applied to a substrate, and the nonuniformity in thickness is prevented to arise on the obtained pattern forming layer. In order to achieve the above object, the present invention provides a micropattern transfer method in which a micropattern is transferred to a resin by pressing a stamper having the micropattern onto the resin applied to a substrate, including the steps of: applying the resin to a surface of the substrate discretely in order to obtain a plurality of resin islands so that a center portion of each of the resin islands forms a planar thin-film, and a peripheral portion of the resin island rises higher than the center portion. |
US08562893B2 |
Molding method and molding device for forming impeller
A molding method for forming an impeller, includes a mold clamping process having a first mold for forming one side of blades, a second mold firmly clamped with the first mold, and a core arranged at the first mold relative to the blades, the mold clamping process clamping the first mold to the second mold in a state where the core is arranged between the first mold and the second mold, an injecting process injecting resin in a cavity obtained by the mold clamping process, and a mold removing process including the steps of releasing at least the first mold from the clamped state obtained by the mold clamping process to generate an opened portion in the first mold after the resin is hardened, rotating the core about a rotational axis toward the opened portion of the first mold, and separating the core from the resin-molded impeller. |
US08562892B2 |
Mechanical process for producing particles in a fluid
A method for producing particles includes providing a first patterned surface having a first surface relief pattern adapted to impart structure to a plurality of particles while they are under production; providing a second patterned surface having a second surface relief pattern adapted to impart structure to a plurality of particles while they are under production; depositing a particle material in contact with at least one of the first patterned surface and the second patterned surface; aligning the first surface relief pattern on the first patterned surface with respect to the second surface relief pattern on the second patterned surface; contacting at least a portion of the first patterned surface with at least a portion of the second patterned surface; solidifying at least a portion of the particle material to form a plurality of particles; and separating at least a portion of the plurality of particles from at least one of the first patterned surface and the second patterned surface. The at least a portion of a structure of each of the plurality of particles is imparted by a combination of the first surface relief pattern and the second surface relief pattern. |
US08562889B2 |
Method for producing plastic cylinder head cover
A method produces a plastic cylinder head cover having an oil control valve holder as an integral part thereof by insert molding. The method includes a step of setting the oil control valve holder in one of a pair of molds that can approach and separate from each other; and a step of clamping the pair of molds and injecting plastic material. In the step of injecting plastic material, the oil control valve holder is set in the one mold with an insert pin being inserted in a hole thereof.Another a method produces a plastic cylinder head cover having an oil control valve holder as an integral part thereof by insert molding. The oil control valve holder includes a mounting surface on which it is mounted to a cylinder head, a hole oriented along an axis inclined to a plane direction of the mounting surface, and two faces containing open ends of the hole. The method includes a step of setting the oil control valve holder in one of a pair of molds that can approach and separate from each other; and a step of clamping the pair of molds and injecting plastic material. In the step of injecting plastic material, the oil control valve holder is set in the one mold with an abutment insert being abutted against the mounting surface near one of the two faces having a larger area than the other. |
US08562888B2 |
Portable sealant dispense system
A system and method for dispensing a sealant over aircraft fasteners secured to a surface in the aircraft. The system includes a nozzle tip having a shroud configured for placement over the fasteners. Sealant is metered to the shroud via an orifice within the nozzle tip. The shroud is sized to leave a space between it and the fastener to control the amount of sealant applied to the fastener upper surface and along the interface between the fastener and aircraft surface. Pressurized fluid urges the sealant through the orifice. |
US08562887B2 |
Fabrication method of multi-functional composites from pre/post-consumer carpet
A method of fabricating a composite panel is disclosed. The method includes cutting a portion of carpet, applying vacuum to the carpet portion, transferring resin into the carpet portion under vacuum, and curing the resin impregnated carpet portion. |
US08562884B2 |
Partition assembly made with partitions having rounded edges and method of making same
A partition assembly comprising a partition matrix made up of intersecting first and second slotted partitions, each of the partitions having at least one slot and a rounded edge. The slots of the partitions are engaged with each other at a plurality of intersections. The partitions are made by rounding an edge of a multi-layered blank using a rotatable tool and then cutting the partition material to a desired size. Slots may then be formed in the edge sealed material. |
US08562883B2 |
Apparatus and method for pelletizing wax and wax-like materials
An apparatus and method for the pelletization of waxes, wax-like and other materials having a sharp melt point include a vessel for forming the wax into a hot molten material. A heat exchanger then cools the molten wax to a temperature just above its melt temperature. The cooled liquid wax is fed to an extruder which further reduces the temperature and mixes the liquid wax into a thoroughly mixed extrudable solid wax. The solid wax is then extruded through die orifices of a die plate into a cutting chamber, and a rotary cutter cooperating with the die face of the die plate cuts the extruded solid wax strands into pellets. The die plate, cutting chamber and rotary cutter can have the same structure as an underwater pelletizer, but operating without water or liquid as a dry face pelletizer. The thus formed wax pellets drop out of the cutting chamber by gravity through an opening in the bottom thereof. |
US08562881B2 |
Fibre composite profile component and process and apparatus for continuous production
A process for continuous production of profile components of fiber composite material by a forming chain system, an associated profile component and the chain system for its continuous production. The method draws on the forming chain system having at least one forming chain. Here, preform batch of fiber strands, impregnated with matrix material and/or woven fiber webs, knit webs or nonwoven webs, are brought to the system at the working run of the at least one forming chain and are guided through the forming chain system, forming a continuous profile containing the profile component with a variable cross section over the profile length and/or with a profile longitudinal axis with virtually any desired extent. The profile components can be provided with local reinforcements, add-on parts of inserts, for example, for introducing force, as early as during primary forming. |
US08562878B1 |
Stress-tuned conductor-polymer composite for use in sensors
A method for making a composite polymeric material with electrical conductivity determined by stress-tuning of the conductor-polymer composite, and sensors made with the stress-tuned conductor-polymer composite made by this method. Stress tuning is achieved by mixing a miscible liquid into the polymer precursor solution or by absorbing into the precursor solution a soluble compound from vapor in contact with the polymer precursor solution. The conductor may or may not be ordered by application of a magnetic field. The composite is formed by polymerization with the stress-tuning agent in the polymer matrix. The stress-tuning agent is removed following polymerization to produce a conductor-polymer composite with a stress field that depends on the amount of stress-tuning agent employed. |
US08562874B2 |
Method for preparation of well-dispersed, discrete nanoparticles by spray drying techniques
A method for preparing uniquely sized nanoparticles of CaF2 by simultaneously spray drying a first NH4F and a biocompatible salt solution and a second Ca(OH)2 and biocompatible salt solution to form CaF2 solid particles in a soluble salt matrix wherein the salt is more soluble than CaF2. The salt matrix may then be dissolved and the separate CaF2 nanosized particles collected for use as a dental therapeutic material. The technique is useful in the preparation of other discrete, nanoparticle sized compounds and combinations by carefully choosing the solvents and solutes of the two spray dried solutions. |
US08562873B2 |
Flame retarder composition
A flame retardant resin composition comprising a specified metal oxide and/or trivalent phosphorus compound (A) and a specified phosphazene compound (B) together with an aromatic resin (C) added according to necessity. This flame retardant composition when mixed into resins, can provide resin compositions excelling in flame resistance, low smoke emission, heat resistance, moisture absorption resistance, dielectric performance, extrudability, mold release, thermal stability, mechanical properties, etc. |
US08562871B2 |
Composition and associated method
A composition includes a filler dispersed in a polymeric matrix. The filler may be electrically conducting in a temperature range and may have a Curie temperature. The composition may have a trip temperature at which electrical resistance of the composition increases with increase in temperature, and the trip temperature of the composition may be determined by the Curie temperature of the filler. The filler may be present in the polymeric matrix in an amount determined by a property of one or both of the polymeric matrix or the filler. An associated method is provided. |
US08562870B2 |
Polymer dopants
A polymer dopant for electrially conducting, photoconducting and semiconducting components and devices and novel polymers comprising electron accepting groups that are suitable as polymer dopants. |
US08562869B2 |
Porous anode active material, method of preparing the same, and anode and lithium battery employing the same
Provided are a porous anode active material, a method of preparing the same, and an anode and a lithium battery employing the same. The porous anode active material includes fine particles of metallic substance capable of forming a lithium alloy; a crystalline carboneous substance; and a porous carboneous material coating and attaching to the fine particles of metallic substance and the crystalline carboneous substance, the porous anode active material having pores exhibiting a bimodal size distribution with two pore diameter peaks as measured by a Barrett-Joyner-Halenda (BJH) pore size distribution from a nitrogen adsorption. The porous anode active material has the pores having a bimodal size distribution, and thus may efficiently remove a stress occurring due to a difference of expansion between a carboneous material and a metallic active material during charging and discharging. Further, the anode electrode and the lithium battery comprising the anode active material have excellent charge/discharge characteristics. |
US08562868B2 |
Ternary metal transition metal non-oxide nano-particles, methods and applications thereof
The present invention is related to ternary metal transition metal non-oxide nano-particle compositions, methods for preparing the nano-particles, and applications relating in particular to the use of said nano-particles in dispersions, electrodes and capacitors. The nano-particle compositions of the present invention can include a precursor which includes at least one material selected from the group consisting of alkoxides, carboxylates and halides of transition metals, the material including transition metal(s) selected from the group consisting of vanadium, niobium, tantalum, tungsten and molybdenum. |
US08562867B2 |
Organic species that facilitate charge transfer to or from nanostructures
The present invention provides polymeric compositions that can be used to modify charge transport across a nanocrystal surface or within a nanocrystal-containing matrix, as well as methods for making and using the novel compositions. |
US08562866B2 |
Preparation method of zinc manganese silicate
A preparation method of zinc manganese silicate is provided. The method includes the following steps: step 1, preparing silicon dioxide sol with distilled water, anhydrous ethanol and tetraethyl orthosilicate; step 2, preparing a mixture solution of a zinc salt and a manganese salt; step 3, adjusting the silicon dioxide sol to be neutral or acidic; step 4, adding the mixture solution of the zinc salt and the manganese salt into the silicon dioxide sol to form a gelatin; step 5, drying the gelatin, keeping the temperature, grinding, reducing with keeping the temperature in a reductive atmosphere to obtain zinc manganese silicate. The preparation method has simple technique and low equipment requirement. The particles of the zinc manganese silicate phosphor prepared by the method have a regular size, uniform shape and good luminescent performance. |
US08562856B2 |
Getter systems comprising a gas-sorbing phase in the pores of a porous material distributed in a permeable means
Getter systems are provided having a phase being active in the sorption of gas inserted in the pores of a porous material. The porous material is, in turn, dispersed in a polymeric means that is permeable to the gas to be sorbed. |
US08562854B2 |
Compositions for deicing/anti-icing
A non-toxic deicing/anti-icing fluid includes at least 20% by weight of a freeze point depressant selected from short chain polyols having 3 to 5 carbon atoms. The fluid further includes at least 10% by weight of water, a thickener, a surfactant, and a pH moderator. The fluid meets the requirements of SAE/AMS 1428 or its revisions for a non-Newtonian, Type II, III, or IV aircraft deicing/anti-icing fluid. |
US08562840B2 |
Devices and methods for the purification, isolation, desalting or buffer/solvent exchange of substances
A spin column device, which contains a rigid porous filter that retains its shape during centrifugation, chromatography methods using the device to isolate a desired substance, e.g., a biological molecule, from other substances in a mixture, and kits containing the device with one or more reagents for use in the method. |
US08562838B2 |
Method for treating mineral sludge above ground using polymers
Provided is a method for treating sludge from the mining or mineral industry, including before above-ground spreading, contacting the sludge with a flocculating agent that is a water-soluble, organic polymer having a molecular weight of from 5,000,000 to 25,000,000 g/mol and an anionicity of from 10 to 40 mol %, to produce contacted sludge, wherein the water-soluble organic polymer includes at least one anionic monomer having a carboxylic function or having a sulfonic acid function, at least one non-ionic monomer, and optionally one or more cationic monomers, where the flocculating agent is branched, and has from 0.02 to 2 mol % hydrophobic monomers. |
US08562835B2 |
Fluid filter
A fluid filter, particularly suitable for high pressure and high volume use, comprises a cylindrical housing (201) having an attachment plate (209) at an inlet end (202) to which is attached a plurality of bundles (303) of fibers (211), with the fibers being left unsecured at their distal end adjacent an outlet (203) of the housing. Between the bundles is provided a balloon (212) which can be distended in order to crush the fibers around the periphery of the housing. In use, a fluid to be filtered is introduced into the inlet end, adjacent to where the fibers are secured. In order to flush the filter the pressure within the balloon is released, and a flushing fluid is passed through the housing in the same direction. |
US08562831B2 |
Water filter assembly
A water filtration system includes a faucet assembly and a filtration assembly. The filtration assembly includes a filter assembly; a filter bracket or mounting assembly for securing the filter assembly to a support surface or structure; and a filter manifold assembly including an unfiltered water inlet for connecting to an unfiltered water supply and a filtered water outlet for connecting to a valve assembly of the faucet assembly. The filter assembly interfaces with the filter manifold assembly to provide filtered water to the faucet assembly under control of the valve assembly. A filter that otherwise would not interface with the filter bracket/mounting assembly and/or the filter manifold assembly can be adapted to work in the water filtration system by using a filter adaptor assembly. |
US08562830B2 |
Keyed system for connection of filter cartridge to filter holder
Embodiments of a key system for filters and their connecting heads, brackets, or other holders are shown. The filter cartridge and its holder each have a keyed surface, one being a protruding “key” and one being a recessed “lock”. Cooperation of these keyed surfaces is required in order for the filter cartridge to be installed in the holder, so that mis-matched cartridges cannot be installed into the holder, for example, to prevent a particular type of cartridge from being placed in a filtration or other process where it would be inappropriate, or undesired. The keyed surfaces are selectively locate-able preferably at different circumferential locations on a perimeter of the filter and a corresponding location on a perimeter of the head/holder. The perimeter may be, for example, on an outer shoulder surface of a filter and an inner surface of a valve head, or on outer and inner surfaces of connectors that provide a liquid seal between the filter and the head/holder. |
US08562823B2 |
Dynamic weight balancing of flow in kidney failure treatment systems
A kidney failure treatment system includes: (i) a dialysate supply; (ii) a weighing device; a control container coupled operably to the weighing device; (iii) a diffusion membrane; (iv) a drain; first and second pumps; (v) a first fluid conduit coupled fluidly to the dialysate supply and the diffusion membrane, the first fluid conduit coupled operably to the first pump; (vi) a second fluid conduit coupled fluidly to the control container and the drain, the second fluid conduit coupled operably to the first pump; and (vii) a third fluid conduit coupled fluidly to the diffusion membrane and the control conduit, the third fluid conduit coupled operably to the second pump. |
US08562821B2 |
Process for the removal of sulfones from oxidized hydrocarbon fuels
Described herein is a process for the removal of sulfones by mesoporous silica adsorbents having narrow pore size distribution which could be controlled to specification for the selective removal of sulfones from oxidized hydrocarbon fuels wherein the sulfones were present due to oxidative conversion of organo-sulfur compounds by a suitable oxidizing solution. The mesoporous adsorbents showed typically 2-18 times higher equilibrium loading capacity for sulfones in comparison to the commercially available adsorbents. |
US08562819B2 |
Process to manufacture a base stock and a base oil manufacturing plant
We provide a process to manufacture a base stock, comprising hydrocracking, separating, and dewaxing, wherein the base stock has a ratio of Noack volatility to CCS VIS at −25° C. multiplied by 100 from 0.15 to 0.40. We also provide a base stock made by a process, and a base oil manufacturing plant that produces the base stock. |
US08562818B2 |
Hydrocarbon composition
A hydrocarbon composition is provided containing: at least 5 wt. % of hydrocarbons having boiling point in the range from an initial boiling point of the composition up to 204° C.; at least 10 wt. % of hydrocarbons having a boiling point in the range from 204° C. up to 260° C.; at least 25 wt. % of hydrocarbons having a boiling point in the range from 260° C. up to 343° C.; at least 30 wt. % gram of hydrocarbons having a boiling point in the range from 343° C. to 538° C.; and at most 3 wt. % of hydrocarbons having a boiling point of greater than 538° C.; wherein the composition contains aromatic hydrocarbons including mono-aromatic hydrocarbons, di-aromatic hydrocarbons, and polyaromatic hydrocarbons, where the combined mono-aromatic hydrocarbon compounds and di-aromatic hydrocarbon compounds are present in a weight ratio relative to the polyaromatic hydrocarbon compounds of at least 1.5:1.0. |
US08562809B2 |
Chitosan-coated wires for biosensing
A method of forming a bioelectronic device including a protein on an electrically conductive substrate, by electrodepositing aminopolysaccharide chitosan on the substrate while applying a cathodic voltage to the substrate, to form an aminopolysaccharide chitosan film thereon, applying an anodic voltage to the substrate in the presence of NaCl to activate the aminopolysaccharide chitosan film so that it is reactive with protein. The method also optionally includes reacting the aminopolysaccharide film, after activation thereof, with the protein, so that the protein assembles on and is coupled to the substrate, thereby forming a bioelectronic device. The protein can include single or multiple protein species, and including biosensing proteins. Additional methods include biosensing of electrochemically active compounds either present in a sample or generated during a biological recognition event and devices useful in such methods. The resulting devices are useful as sensors in hand-held devices, textiles, garments and the like. |
US08562808B2 |
Polymer thick film silver electrode composition for use as a plating link
The invention is directed to a polymer thick film silver composition comprising: (a) conductive silver flakes and (b) an organic medium consisting of (1) acrylic organic polymeric binder; and (2) organic solvent. The composition may be processed at a time and energy sufficient to remove all solvent. The invention is further directed to novel method(s) of circuitry formation on printed wiring board constructions. |
US08562807B2 |
Droplet actuator configurations and methods
Droplet actuators for conducting droplet operations, such as droplet transport and droplet dispensing, are provided. In one embodiment, the droplet actuator may include a substrate including, droplet operations electrodes arranged for conducting droplet operations on a surface of the substrate; and reference electrodes associated with the droplet operations electrodes and extending above the surface of the substrate. Other embodiments of droplet actuators and methods of loading and using such droplet actuators are also provided. |
US08562803B2 |
Electrochemical ion exchange treatment of fluids
A fluid treatment apparatus for treating a fluid comprises an electrochemical cell having fluid orifices to receive and release fluid, and a fluid passageway connecting the orifices with a water-splitting ion exchange membrane is exposed to the fluid in the passageway. First and second electrodes are positioned about the membrane. The apparatus also comprises a controller to control and operate a power supply and valve system. The power supply supplies a current to the first and second electrodes at sufficiently high current density to result in bacteriostasis, deactivation, or a reduction in the microorganisms in the fluid. The controller can also operate a set of cells to deionize fluid and regenerate the cells. |
US08562802B1 |
Transilluminator base and scanner for imaging fluorescent gels, charging devices and portable electrophoresis systems
Cassette electrophoresis systems that allow viewing of molecules during the electrophoresis run are disclosed. Cassette electrophoresis bases that reversibly engage light sources, such as light source bases are disclosed. Also disclosed are visible light transillumination systems for viewing a pattern of fluorescence emitted by fluorophores comprising a cassette housing fluorophore-containing material and a base unit to support the cassette. In some aspects the base unit that includes a power supply also houses a light source having output in the visible wavelength region and a filter placed between the light source and the fluorophores. The system is constructed and arranged such that patterns of fluorescence emitted by the fluorophores are viewable. Also described are charging devices for providing charge to gel electrophoresis systems, portable gel electrophoresis systems and methods of use thereof. |
US08562799B2 |
Flat end-block for carrying a rotatable sputtering target
An end-block for use in a tubular magnetron sputtering apparatus is disclosed. Such an end-block rotatably transfers movement, coolant 5 and electrical current to the target while maintaining vacuum integrity and a closed coolant circuit. It hence comprises a drive means, a rotary electrical contact means, a bearing means, a number of rotary coolant seal means and a number of vacuum seal means. The inventive end-block occupies a minimal axial length along the target thus allowing 10 space savings in existing equipment such as e.g. display coaters. The axial length is reduced by mounting at least two of the means radial to one another. |
US08562796B2 |
Control system and method of use for controlling concentrations of electrolyzed water in CIP applications
Control systems for use of electrolysis solutions for automated recirculating or single-pass cleaning systems, such as clean-in-place (CIP) applications are disclosed. Control systems and methods for using automated chlorine output solutions for various cleaning applications are measurable over broad pH ranges. The control systems generate consistent and predictable electrolytic solutions and include a measurement system that identifies chlorine oxyanion concentration across broad ranges of pH, overcoming the sensitivity of chlorine monitors to pH and permitting use of the control systems to control cleaning systems. |
US08562795B2 |
Nanoscale electric lithography
A nanoscale lithographic method in which a reusable conductive mask, having a pattern of conductive surfaces and insulating surfaces, is positioned upon a substrate whose surface contains an electrically responsive resist layer over a buried conductive layer. When an electric field is applied between the conductive mask and buried conductive layer, the resist layer is altered in portions adjacent the conductive areas of the mask. Selective processing is performed on the surface of the substrate, after mask removal, to remove portions of the resist layer according to the pattern transferred from the mask. The substrate may be a target substrate, or the substrate may be utilized for a lithographic masking step of another substrate. In one aspect of the invention the electrodes to which the charge is applied are divided, such as into a plurality of rows and columns wherein any desired pattern may be created without the need to fabricate specific masks. |
US08562794B2 |
Process for producing reflective mask blank for EUV lithography and process for producing substrate with functional film for the mask blank
To provide a process for producing an EUV mask blank, capable of reducing foreign matter attributable to a sputtering target, and a process for producing a substrate with a functional film for such a mask blank.A process for producing a reflective mask blank for EUVL, which comprises at least a step of forming a Mo/Si multilayer reflective film, a step of forming a ruthenium (Ru) film or Ru compound film as a protective layer on the multilayer reflective film, and a step of forming an absorber layer to absorb EUV light, on the Ru film or Ru compound film, wherein the formation of the Mo film, the Si film, and the Ru film or Ru compound film, is carried out by means of an ion beam sputtering method, and in the formation of the Si film of the Mo/Si multilayer reflective film and in the formation of the Ru film or Ru compound film, the target angle, the type of the process gas, the process gas pressure, the RF power of ion source, the suppresser voltage, the ion beam voltage and the ion beam current are adjusted to be substantially the same; and based on an erosion region of a sputtering target used for the formation of the Si film, an erosion region and a non-erosion region of a sputtering target to be used for the formation of the Ru film or Ru compound film, are predicted, roughening treatment is applied to the non-erosion region thus predicted of the Ru target or Ru compound target, and then the formation of the Ru film or Ru compound film is carried out. |
US08562793B2 |
Method and apparatus for microwave reduction of organic compounds
The invention pertains to utilization of high power density microwave energy to reduce organic compounds to carbon and their constituents, primarily in a gaseous state. The process includes, but is not limited to, scrap tires, plastics, asphalt roofing shingles, computer waste, medical waste, municipal solid waste, construction waste, shale oil, and PCB/PAH/HCB-laden materials. The process includes the steps of feeding organic material into a microwave applicator and exposing the material to microwave energy fed from at least two linear polarized sources in non-parallel alignment to each other, and collecting the material. The at least two sources of microwave energy are from a bifurcated waveguide assembly, whose outputs are perpendicular to each other and fed through waveguide of proper impedance, such that the microwave sources are physically and electrically 90° out of phase to each other. The microwave frequency is between 894 and 1000 MHz, preferably approximately 915 MHz. |
US08562783B2 |
Method for the production of an elastic laminate material web
A method for the production of an elastic laminate material web comprises laminating a cover material onto a carrier film consisting of a thermoplastic elastomer, using a hot-melt glue. The carrier film is rolled off a film roll and has a polymer powder on at least one side, to prevent interlocking of the layers of the carrier film in the film roll. The melt temperature of the powder is less than or equal to the gluing temperature of the hot-melt glue, so that the powder melts during lamination. |
US08562782B2 |
Method and device for interleaving a module or chip
A method for interleaving a module including the cutting out of the module on a strip, the gripping of the cut-out module, the conveying of the module right up to a station for affixing and adhesively bonding modules. The module being heated by a heater via heat conduction of an affixing system upon conveying and then affixing of the preheated module by positioning the head of a first guiding member on the upper portion of a second guiding member forming a mask showing the imprint of the module or chip, preformed on the card, by displacement of the affixing system and of positioning the lower portion of the second guiding member on the surface of the card by displacement of the assembly formed by the affixing system and the second guiding member. A device for interleaving a module is also described. |
US08562776B2 |
Fast electrostatic shutter and method of achieving offset compensation in infrared video imagers using fast shutters
Embodiments of the invention are directed to methods and apparatus for infrared imagers including fast electrostatic shutters and offset compensation. Fast electrostatic shutters are used for video image correction including image offset compensation where temporal noise and scene nonuniformity are corrected. This method provides a shutterless experience for the user because the image will be blocked for only one frame at a time. A method of manufacturing an electrostatic infrared shutter includes a conductive infrared-transparent substrate, covering it with an insulating layer, depositing adhesive and a thin film stack, delineating a working area, providing contacts, heat-treating the assembly, and making the polymer non-reflective in the infrared. |
US08562773B2 |
Method of producing an internal tensioning structure useable with inflatable devices
An internal tensioning structure for use in an inflatable product fulfills the basic function of maintaining two adjacent inflatable surfaces in a desired geometric arrangement when the inflatable product is pressurized. The tensioning structure is formed by connecting a pair of plastic strips sheets via spaced-apart strands, such as strings or wires. When pulled taut, the strands provide a high tensile strength between the two opposed plastic strips. At the same time, the plastic strips facilitate a strong, long-lasting weld between the tensioning structure and the inflatable product. |
US08562772B2 |
Process for applying a layered structure on a lens
This invention relates to an improvement for applying a layered structure onto a convex surface of a lens. After thermoforming the layered structure, a curvature direction of the layered structure is inverted. The structure is then applied on the lens surface by continuously pushing the structure against the lens surface, starting from a contact point between a convex surface of the structure and the convex surface of the lens. The curvature direction of the layered structure is then inverted again, so that it recovers the curvature direction that resulted from thermoforming. Stresses within the layered structure are then reduced, and the structure can be assembled with the lens without defects. |
US08562768B2 |
Solid compounds, self-sustaining combustion hydrogen generators containing borazane and/or polyaminoborane and at least one inorganic oxidant, and method for generating hydrogen
The main subject of the present invention are solid compounds capable of generating hydrogen by a self-sustaining combustion reaction. Their composition comprises borazane and/or polyaminoborane and at least one inorganic oxidant, advantageously chosen from ammonium nitrate, alkali metal nitrates, alkaline-earth metal nitrates, metal nitrates, metal oxides, oxidants of the family of dinitramines and mixtures thereof. It also relates to the generation of hydrogen by self-sustaining combustion of at least one such compound. |
US08562766B2 |
Method for making a low surface roughness cast strip
A thin cast strip is formed having at least one microstructure selected from the group consisting of polygonal ferrite, acicular ferrite, Widmanstatten, bainite and martinsite, a surface roughness of less than 1.5 microns Ra and a scale thickness of less than about 10 microns by applying a mixture of water and oil on the work rolls of the hot rolling mill, passing the thin cast strip at a temperature of less than 1100° C. through the hot rolling mill while the mixture of oil and water is applied to the work rolls, and shrouding the thin cast strip from the casting rolls through the hot rolling mill in an atmosphere of less than 5% oxygen to form the thin cast strip. |
US08562762B2 |
High strength hot rolled steel products for line-pipes excellent in low temperature toughness and production method of the same
The present invention provides high strength hot rolled steel plate for line-pipes superior in low temperature toughness, and a method of production of the same, containing, by mass %, C: 0.01 to 0.1%, Si: 0.05 to 0.5%, Mn: 1 to 2%, P: ≦0.03%, S: ≦0.005%, O: ≦0.003%, Al: 0.005 to 0.05%, N: 0.0015 to 0.006%, Nb: 0.005 to 0.08%, and Ti: 0.005 to 0.02%, where N−14/48×Ti>0% and Nb−93/14×(N−14/48×Ti)>0.005%, and a balance of Fe and unavoidable impurities, said steel plate characterized in that its microstructure is a continuously cooled transformed structure, a reflected X-ray intensity ratio {211}/{111} of the {211} plane and {111} plane parallel to the plate surface in the texture at the center of plate thickness is 1.1 or more, and an in-grain precipitate density of the precipitates of Nb and/or Ti carbonitrides is 1017 to 1018/cm3. |
US08562758B2 |
Austenitic-ferritic stainless steel
A low Ni and high N austenitic-ferritic stainless steel is disclosed. It includes an austenitic-ferritic stainless steel having high formability and punch stretchability, crevice corrosion resistance, corrosion resistance at welded part, or excellent intergranular corrosion resistance, from a stainless steel structured by mainly austenite phase and ferrite phase, and consisting essentially of 0.2% or less C, 4% or less Si, 12% or less Mn, 0.1% or less P, 0.03% or less S, 15 to 35% Cr, 3% or less Ni, and 0.05 to 0.6% N, by mass, by adjusting the percentage of the austenite phase in a range from 10 to 85%, by volume. Furthermore, it includes an austenitic-ferritic stainless steel having higher formability by adjusting the amount of (C+N) in the austenite phase to a range from 0.16 to 2% by mass. |
US08562755B1 |
Anti-tin whisker solder
A lead-free solder composition including about 90% to about 99% by weight of a lead-free tin solder based on the total weight of the lead-free solder composition and about 1% to about 10% by weight of a polyhedral oligomeric silsesquioxane based on the total weight of the lead-free solder composition. |
US08562753B2 |
Nozzle cleaning method and a computer-readable storage medium storing nozzle cleaning program
Disclosed are a nozzle cleaning apparatus and a nozzle cleaning method, which are capable of effectively cleaning a nozzle for discharging a process liquid to a substrate. A nozzle 30 is accommodated in a cleaning container 2 having a funnel-shaped portion 2b. A solvent T as a cleaning liquid is supplied along an inner surface of the funnel-shaped portion 2b. The solvent T forms a vortex flow whirling around the nozzle 30. By exposing the nozzle 30 to the vortex flow, the nozzle 30 can be effectively, thoroughly cleaned. |
US08562752B2 |
Single workpiece processing chamber
A process chamber for processing semi-conductor wafers. The chamber includes at least one rotor within the process chamber. The rotor is adapted to receive and/or process semi-conductor wafers. The top of the process chamber also includes a tiltable rim. This rim tilts from a non-inclined position to an inclined position. The wafers may be loaded into and unloaded from the process chamber when the rim is in its inclined position. |
US08562748B1 |
Multiple cleaning processes in a single tank
Methods of cleaning workpieces are described. One method includes performing both a sonication cleaning operation and a rinse cleaning operation within a single cleaning tank. Another cleaning method described includes the use of cross flow of cleaning liquid within a cleaning tank while performing a rinse clean. The cleaning method includes the oscillation of one or more workpieces in the cleaning tank to perform the rinse clean. |
US08562745B2 |
Stable wafer-carrier system
One embodiment of the present invention provides a wafer-carrier system used in a deposition chamber for carrying wafers. The wafer-carrier system includes a base susceptor and a top susceptor nested inside the base susceptor with its wafer-mounting side facing the base susceptor's wafer-mounting side, thereby forming a substantially enclosed narrow channel. The base susceptor provides an upward support to the top susceptor. |
US08562743B2 |
Method and apparatus for atomic layer deposition
A high pressure processing system including a chamber configured to house a substrate. A fluid introduction system includes at least one composition supply system configured to supply a first composition and a second composition, and at least one fluid supply system configured to supply a fluid. The fluid supply system is configured to alternately and discontinuously introduce the first composition and the second composition to the chamber within the fluid. |
US08562742B2 |
Apparatus for radial delivery of gas to a chamber and methods of use thereof
Apparatus for the delivery of a gas to a chamber and methods of use thereof are provided herein. In some embodiments, a gas distribution system for a process chamber may include a body having a first surface configured to couple the body to an interior surface of a process chamber, the body having a opening disposed through the body; a flange disposed proximate a first end of the opening opposite the first surface of the body, the flange extending inwardly into the opening and configured to support a window thereon; and a plurality of gas distribution channels disposed within the body and fluidly coupling a channel disposed within the body and around the opening to a plurality of holes disposed in the flange, wherein the plurality of holes are disposed radially about the flange. |
US08562741B2 |
Evaporation source for evaporating an organic electroluminescent layer
The present invention relates to an evaporation source for evaporating an organic electroluminescent layer. In particular, the present invention relates to the evaporation source preventing an aperture, through which a vaporized evaporation material is emitted, from being clogged by restricting heat transfer to outward. The evaporation source according to the present invention includes a cell retaining an evaporation material therein; a cell cap installed on the upper part of the cell and having a cell cap aperture for emitting a vaporized evaporation material; an external wall placed in the outside of the cell to support a heating means set up at the outside of the cell; a cover placed above the cell cap, fixed to the upper end of the external wall, and having a cover aperture corresponding to the cell cap aperture; and a shut-off plate placed between the cover and the cell cap and having a shut-off plate aperture corresponding to the cell cap aperture and the cover aperture in the center of the shut-off plate. |
US08562739B2 |
Silica glass crucible for pulling up silicon single crystal and method for manufacturing thereof
A silica glass crucible used for pulling up a silicon single crystal and made from natural silica a raw material is provided with a region within a certain range from the center of a bottom section of the crucible and up to 0.5 mm deep from an inner surface and which substantially does not include gas bubbles, wherein an average value of a concentration of Al included in a region within the certain range from the center of the bottom section of the crucible and up to 0.5 mm deep from the inner surface is 30 ppm or more and 150 ppm or less. In the case where the inner layer of the crucible bottom section is formed in this way, dents in the inner surface are prevented and the generation of gas bubbles is reduced. |
US08562738B2 |
Nitride-based light-emitting device
A nitride-based light-emitting device includes a substrate and a plurality of layers formed over the substrate in the following sequence: a nitride-based buffer layer formed by nitrogen, a first group III element, and optionally, a second group III element, a first nitride-based semiconductor layer, a light-emitting layer, and a second nitride-based semiconductor layer. |
US08562735B2 |
Incinerator fly ash geopolymer and method
A geopolymer concrete formed by mixing about 3% to about 43% by weight incinerator fly ash, about 3% to about 35% by weight coal fly ash, about 7% to about 38% by weight alkaline activator liquid, and about 31% to about 70% by weight aggregate. The incinerator fly ash may be derived from a solid waste incinerator facility. The alkaline activator liquid may include a sodium hydroxide solution and sodium silicate. The aggregate may include a fine aggregate, such as sand, and a coarse aggregate, such as gravel. |
US08562734B2 |
Low calcium cementitious material and method of manufacturing low calcium cement
A low-calcium-cementitious material having a calcium oxide content less than or equal to 10 wt % which is processed at room temperature into a low calcium cement mainly composed of mullite and a method manufacturing of the low calcium cement are provided. The low-calcium-cementitious material includes low calcium fly ash, an alkaline agent, and a congealing agent, wherein the calcium oxide content of the low-calcium-cementitious material is less than or equal to 10 wt %. The low calcium fly ash has a calcium oxide content less than or equal to 10 wt %. The low calcium cement manufacturing method includes providing a low calcium fly ash having a calcium oxide content less than or equal to 10 wt %; providing an alkaline agent; providing a congealing agent; and mixing the low-calcium-content fly ash, the alkaline agent, and the congealing agent and standing the mixture at room temperature to form a low calcium cement. |
US08562730B2 |
Ink composition for inkjet printing on substrate material comprising polyvinyl chloride
There is disclosed an ink composition and a method of printing and using ink on substrate material comprising polyvinyl chloride with thermal inkjet, drop on demand piezo inkjet, or continuous inkjet by depositing ink comprising vinyl-penetrating solvent, colorant and non-aqueous carrier solvent, the ink being free from polymerizable resins and binders. |
US08562729B2 |
Highlighting ink formulation comprising an anti-smear agent
The disclosure is generally related to highlighting ink formulations and writing instruments containing the same. The disclosure provides a highlighting ink formulation that includes a solvent system, a colorant dispersed or dissolved in the solvent system, and an anti-smear agent dispersed or dissolved in the solvent system, wherein the anti-smear agent includes a monovalent cation and/or a divalent cation. |
US08562728B2 |
Process for preparing proton-conducting clay particles and composite material comprising such particles
The invention relates to a process for preparing proton-conducting clay particles, successively comprising the following steps: a) a step of activating a clay powder, comprising a step in which the said powder is subjected to a gas plasma; b) a grafting step comprising a step of placing the activated powder obtained from step a) in contact with a solution comprising at least one compound comprising at least one group chosen from —PO3H2, —CO2H and —SO3H and salts thereof and comprising at least one group capable of grafting onto the surface of the said powder. Use of these particles for the manufacture of fuel cell membranes. |
US08562726B2 |
Chamber air cleaner and an intake apparatus for engine including the same
A chamber air cleaner apparatus may include a chamber housing mounted through a connector onto an air hose wherein the air hose may be connected to a main air cleaner, an intake duct attached to an outer surface of the chamber housing wherein exterior air may be introduced into the chamber housing through the intake duct, a variable valve pivotally installed in the vicinity of the intake duct and selectively opening according to an air suction pressure applied thereto, and a filter element mounted between the intake duct and the connector within the chamber housing to purify the introduced air through the intake duct. |
US08562724B2 |
Methods and systems for removing pollutants from fluid stream
A pollutant removal system for use with a power generation system includes a particulate control device configured to remove particulates from a flue gas stream produced within the power generation system. The particulate control device is cleaned on a predetermined cleaning cycle. The pollutant removal system also includes a sorbent control system for controllably injecting a sorbent into the flue gas stream upstream of the particulate control device. The sorbent control system is configured to adjust a sorbent injection rate as a function of the cleaning cycle. |
US08562723B2 |
Product gas concentrator and method associated therewith
Various equipment and methods associated with providing a concentrated product gas are provided. In one embodiment, the equipment includes an input device first and second sieve tanks, a variable restrictor, and a controller. In one embodiment, the method includes: a) selecting a desired output setting for the concentrated product gas from a plurality of output settings, b) separating one or more adsorbable components from a pressurized source gaseous mixture via first and second sieve tanks in alternating and opposing pressurization and purging cycles to form the concentrated product gas, and c) selectively controlling a variable restrictor based at least in part on the desired output setting to selectively provide flow between the first and second sieve tanks such that the flow for at least one output setting is different from the flow for at least one other output setting in relation to corresponding pressurization cycles. |
US08562719B2 |
System for acid gas removal
A gas purification system including a hydrogen sulfide (H2S) absorber, a carbon dioxide (CO2) absorber, a flash tank, and a H2S concentrator. The gas purification system may also include a gas path though the H2S absorber prior to the CO2 absorber, a first solvent path sequentially through the CO2 absorber, the H2S absorber, and the H2S concentrator, and a second solvent path sequentially through the CO2 absorber, the flash tank, and the H2S concentrator, wherein the first and second solvent paths flow a common solvent. |
US08562716B2 |
Device and method for degassing a liquid
A method for degassing a liquid of a substantially closed liquid circulation system at a working pressure may include passing at least a partial flow of the liquid through a restriction into a chamber in which a degassing pressure is maintained, the degassing pressure being higher than atmospheric pressure and lower than the working pressure; separating gas withdrawn from the partial flow of liquid from the partial flow; removing the gas from the chamber; and pumping the degassed partial flow of the liquid back into the substantially closed circulation system. The restriction may include a nozzle, and the step of passing at least the partial flow of the liquid through the restriction into the chamber may include spraying at least the partial flow of the liquid through the nozzle into the chamber for obtaining a jet and/or mist of the liquid in the chamber. |
US08562714B2 |
Article having a dispersion of ultrafine titanium boride particles in a titanium-base matrix
An article includes a microscale composite material having a matrix with titanium boride particles configured to form an insert in a metallic mass being comprised of material other than a consolidated titanium-based metallic composition having titanium particles. |
US08562713B2 |
Flexible minimum energy utilization electric arc furnace system and processes for making steel products
A combined arc furnace, ladle metallurgical furnace and vacuum degassing system having the flexibility to produce at least non-vacuum arc remelt, vacuum arc remelt, vacuum oxygen decarburized non-vacuum arc remelt, and vacuum oxygen decarburized vacuum arc remelt steels from one off to continuous casting end uses in steady state or randomized order which utilizes only a minimum of energy attributable to preheating hot metal contacting components of the system followed by heat loss reduction of the components and use of a carryover heel in the arc furnace, in which the throughput of the system is limited solely by the melting capacity of the arc furnace. |
US08562711B2 |
Additive containing N-(n-butyl)thiophsphoric triamide for urea-based fertilizer
A dry flowable additive for aqueous urea-based fertilizers made of solid urea formaldehyde polymer (UFP), N-(n-butyl) thiophosphoric triamide (NBPT), and, optionally, dicyandiamide (DCD), wherein the liquid fertilizer containing the additive provides reduced nitrogen loss from the soil. Optionally, the dry additive may also be blended with molten or solid urea to form a solid urea-based fertilizer with reduced nitrogen loss from the soil. |
US08562705B2 |
Multistage cyclonic separating apparatus
A cyclonic separating apparatus includes a first cyclonic separating unit including at least one first cyclone and an annular dust collecting chamber, a second cyclonic separating unit located downstream of the first cyclonic separating unit and including at least one second cyclone and a dust collecting chamber, and a third cyclonic separating unit located downstream of the second cyclonic separating unit and including a plurality of third cyclones arranged in parallel and a dust collecting chamber. The number of third cyclones is higher than the number of second cyclones, and the dust collecting chambers of the second and third cyclonic separating units are located inside of the annular dust collecting chamber of the first cyclonic separating unit. |
US08562703B2 |
Thermally stable diamond polycrystalline diamond constructions
Thermally stable diamond constructions comprise a diamond body having a plurality of bonded diamond crystals and a plurality of interstitial regions disposed among the crystals. A metallic substrate is attached to the diamond body. A working surface is positioned along an outside portion of the diamond body, and the diamond body comprises a first region that is substantially free of a catalyst material, and a second region that includes the catalyst material. The diamond body first region extends from the working surface to depth of at least about 0.02 mm to a depth of less than about 0.09 mm. The diamond body includes diamond crystals having an average diamond grain size of greater than about 0.02 mm, and comprises at least 85 percent by volume diamond based on the total volume of the diamond body. |
US08562700B2 |
Multi-functional compact fuel converter and a process for converting liquid fuel
A compact multi-functional fuel converter and a process for converting liquid fuel to a product, which includes providing a supply of oxygen gas, providing a supply of liquid fuel, electrically atomizing the fuel, evaporating the fuel and catalytically reacting the liquid fuel and oxygen in the reactor. |
US08562699B2 |
Pyrolysis waste and biomass treatment
The present invention provides methods and apparatus for treating waste, such as municipal waste via pyrolysis and yielding one or more of heat energy, electrical energy and fuel. In some embodiments, waste feed stock can be municipal waste in black bag form. In some the present invention additionally provides for processing of thousands of tons of municipal waste each day. |
US08562696B2 |
Connecting device
In order to produce a connecting device for the electrically conductive connection of a plurality of cell terminals of electro-chemical cells of an electro-chemical device which enables the cell connector to be mounted on the electro-chemical cells in a simple and rapid manner wherein the device comprises two or more cell connectors for respectively connecting two cell terminals of different electro-chemical cells to one another in electrically conductive manner, it is proposed that, in an assembly state of the connecting device, at least two cell connectors be integrally connected together after separating out the cell connectors from a starting material. |
US08562695B2 |
Solid electrolytic capacitor and a method for manufacturing the same
A method of manufacturing a solid electrolytic capacitor includes steps (a) to (d). The step (a) forms at least two punched apertures in a metal plate, thereby forming a rung section between adjacent two of the punched apertures, the rung section having surfaces as a pair appearing as a result of formation of the punched apertures. The step (b) cuts the rung section out of the metal plate to form a pad member, the length of the rung section corresponding to a distance between the surfaces being determined to be the height of the pad member. The step (c) mounts the pad member on an anode terminal such that one of the surfaces faces the anode terminal. The step (d) electrically connects an anode section of a capacitor element to the other of the surfaces and electrically connects a cathode section of the capacitor element to the cathode terminal. |
US08562692B2 |
Distal lock for a prosthetic hard socket
A lock connects the distal end of a liner to the distal end of the hard socket of a prosthetic leg, and limits or prevents air flow into the hard socket through the distal lock mechanism, even when vacuum is established inside the socket. The distal lock normally is latched, but can be conveniently unlatched by swinging a cammed latch handle. The liner pin may be inserted and locked into the distal lock, without the distal lock being unlatched and without losing the internal air seal preventing air flow through passages of the lock. A slidable, biased lock blade, and interaction between slanted surfaces of the blade and the liner pin, allow the pin to slide down, but not up, past the blade. The latch handle does protrude radially outward a significant distance, when the lock is unlatched, but, as soon as the lock is latched, the handle resides against and/or near the outer surface of the lock housing. |
US08562690B1 |
Modular revision femoral prosthesis
A femoral prosthesis for use during a revision procedure includes a proximal body, a distal stem, a modular neck, and a head. In operation, a surgeon may stabilize the proximal body and the distal stem of the prosthesis in a patient's femoral canal that has moderate loss of metaphyseal cancellous bone (known as a Paprosky Type I femoral defect), extensive loss of metaphyseal cancellous bone (known as a Paprosky Type II femoral defect), or extensive metaphyseal deterioration and some diaphyseal deterioration (known as a Paprosky Type IIIA femoral defect). Without disturbing this arrangement, the surgeon may then position the head in a desired location by selecting a desired modular neck to obtain proper joint kinematics. |
US08562683B2 |
System and method for spinal fusion
The current invention is directed to a system and method for fusing two adjacent vertebrae. In one embodiment, the vertebrae are fused by inserting a self-broaching interbody apparatus into a disc space without the need for separately drilling and broaching. The self-broaching interbody apparatus may include cutting flutes or other broaching means capable of cutting through the cartilaginous endplates of the vertebrae. In another embodiment, an interbody apparatus with an expanding means capable of distracting the disc space between the adjacent vertebrae is inserted into the disc space. Another embodiment includes a sleeve that fits around an interbody apparatus that has at least one opening in its outer surface leading to a cavity filled with bone and/or ortho-biological materials. |
US08562681B2 |
Laminoplasty implant, method and instrumentation
In one embodiment, the present invention is a system for use in a laminoplasty procedure, the system including an implant comprising a first body and a second body, the first and second bodies adapted to slide relative to one another; and an implantation instrument including: a shaft having a longitudinal length, a proximal end, a distal end and a hollow throughbore along at least a portion of its length; a handle positioned on the proximal end of the shaft; an actuator rod having a proximal portion and a distal portion, the actuator rod being positioned within the hollow throughbore of the shaft; a knob adapted to engage the proximal portion of the actuator rod; a first connector adapted to engage the distal portion of the actuator rod; and a second connector fixedly secured to the distal end of the shaft. |
US08562678B2 |
Surgically implantable electronic and/or electromechanical prosthetic device enclosed in an inner bladder surrounded by an outer bladder and having an internal sipe between bladders
A prosthetic device configured for surgical implantation including at least a part of an electronic and/or electromechanical device and comprising an outer chamber, compartment, or bladder; an inner chamber, compartment, or bladder inside the outer chamber, compartment, or bladder; and an internal sipe separating at least a part of the outer chamber, compartment, or bladder and at least a part of the inner chamber, compartment, or bladder. The internal sipe is formed by at least a portion of an inner surface of the outer chamber, compartment, or bladder and at least a portion of an outer surface of the inner chamber, compartment, or bladder. The inner and outer surface portions forming the internal sipe oppose each other and can move relative to each other in a sliding motion. At least a portion of an outer surface of the outer chamber, compartment, or bladder is proximate to an outer surface of the prosthetic device. |
US08562673B2 |
Stented transcatheter prosthetic heart valve delivery system and method
A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer. |
US08562671B2 |
Scaffolds for artificial heart valves and vascular structures
The invention relates to scaffolds for artificial heart valves and vascular structures comprising a biocompatible block copolymer. A method and means for producing said scaffold are also provided. |
US08562670B2 |
Implantable prosthesis with depot retention feature
A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a drug-polymer composition that hydrolytically degrades upon implantation. The inner surface of the through-hole can be an entirely smooth and continuous area that is concave or convex, with no geometric discontinuities. The inner surface of the through-hole can include any number of constricted and distended regions to form grooves of a size and shape carefully selected to engage a corresponding geometric feature of the bioabsorbable depot. |
US08562669B2 |
Methods of application of coatings composed of hydrophobic, high glass transition polymers with tunable drug release rates
The present invention relates to methods of applying a drug—polymer coating layer onto an implantable medical device or another substrate, and the use of a choice of solvents to adjust the release of the drug from the coating. The drug to polymer ratio is about 1:1 to 1:3 on a mass basis. The polymer and the drug are hydrophobic. |
US08562668B2 |
Implant having high fatigue resistance, delivery system, and method of use
According to one aspect of the present invention, a fatigue resistant stent comprises a flexible tubular structure having an inside diameter, an outside diameter, and a sidewall therebetween and having apertures extending through the sidewall. According to other aspects of the invention, processes for making a fatigue resistant stent are disclosed. According to further aspects of the invention, delivery systems for a fatigue resistant stent and methods of use are provided. |
US08562667B2 |
Aneurysm treatment device and method of use
The present invention is directed to aneurysm treatment devices which are capable of being delivered to the situs of a vascular aneurysm through a catheter. The treatment devices comprise, in general, a body member formed by at least one support member and a reactive material selectively applied to the at least one support member. The body member provide support mechanical support to a weakened or otherwise incompetent blood vessel. The reactive material is capable of restricting or occluding blood flow to the aneurysm, without substantially affecting blood flow through the blood vessel. |
US08562663B2 |
Devices and methods for loading a prosthesis onto a delivery system
In an embodiment, a device for loading a prosthesis onto a delivery system comprises a cap and a reducing member. The cap has a piston member that seats a prosthesis. The piston member has at least one side wall configured to contact a portion of the side of the prosthesis seated therein. The reducing member has a conical wall, a first open end, and a second open end. The first open end is configured to receive the piston member. The reducing member reduces an external dimension of at least a portion of the prosthesis seated in the piston member as the prosthesis is moved along an inner surface of the conical wall. |
US08562653B2 |
Surgical tether apparatus and methods of use
A spinal treatment system includes a constraint device having an upper tether portion, a lower tether portion and a compliance member coupled therebetween. The upper tether portion is coupled with a superior spinous process of a spinal segment in a patient and the lower tether portion is coupled with an inferior spinous process or sacrum of the spinal segment. The length or tension in the constraint device is adjustable so that the construct of the tether portions and the compliance member provides a force resistant to flexion of the spinal segment. The system also includes a first prosthesis coupled with the spinal segment, wherein the constraint device modulates loads borne by the prosthesis or by tissue adjacent thereto. |
US08562650B2 |
Percutaneous spinous process fusion plate assembly and method
A spinal implant helps stabilize vertebrae for fusion. The implant is particularly adapted for percutaneous implantation, but may also be used with other access techniques. The implant includes first and second plates that extend through a slot in a frame. When installed, the frame extends laterally through the interspinous space, and the plates extend superiorly-inferiorly along respective lateral sides of the spinous processes. The plates are moved toward one another and relative to the slot to clamp the implant to the spinous processes. The slot may be variably sized along its length, and the plates may move into differently sized portions of the slot during the clamping process. |
US08562649B2 |
System and method for multiple level facet joint arthroplasty and fusion
Facet joint replacement implants may be designed for use on multiple adjacent vertebral levels. Each superior implant may have a substantially semispherical concave surface, and each inferior implant may have a cooperating semispherical convex surface that is deformable to enable it to be pressed into the superior implant concave surface to fix the relative orientations of the superior and inferior implants. Thus, the inferior implant may be attached to the same pedicle as the superior implant, but may also be oriented independently of the superior implant and then fixed in position. Similar mounting structures may be used to attach one or more fusion implants to a level adjacent to that of a facet joint replacement implant. |
US08562648B2 |
Intervertebral implant with movement resistant structure
An implant unit used in surgery has a body made from osteogenic implantable material and including an implant portion and a retaining portion, which is coupled to and extends transversely to the implant portion. The retaining portion is attached to the sidewall of the adjoining vertebral body or mammal bone to prevent displacement of the implant portion relative to the vertebral body or mammal bone and to accelerate fusion therebetween. |
US08562647B2 |
Method and apparatus for securing soft tissue to bone
A method and apparatus for securing soft tissue to bone can include forming a bore in the bone and carrying a flexible suture anchor into the bore. The flexible anchor can include a passage and can be coupled to a suture construct. The suture construct can include at least one self-locking adjustable loop, and the flexible anchor can include a first profile while being carried into the bore. A shape of the flexible anchor can be changed from the first profile to a second profile forming an anchoring mass to retain the flexible anchor in the bore. Tension can be applied to a portion of the suture construct to reduce a size of the self-locking adjustable loop and secure the soft tissue relative to the flexible anchor and the bone. |
US08562642B2 |
Method and apparatus for tissue resection
A resection device includes an elongated probe shaft and a tissue resection member disposed at a distal end of the elongated probe shaft. The tissue resection member has a cutting surface configured for being placed in contact with tissue. In one aspect of the invention, at least one ejection port is located adjacent to the cutting surface of the tissue resection member, wherein the at least one ejection port is coupled to a source of a polymerizable hemostasis-promoting material that is delivered to the resection site of interest. In certain embodiments, polymerization of the hemostasis-promoting material may be accelerated by application of heat, radiofrequency energy, or ultra violet light. |
US08562641B2 |
Laparoscopic instruments
Laparoscopic instruments and trocars are provided for performing laparoscopic procedures entirely through the umbilicus. A generally C-shaped trocar provides increased work space between the hands of the surgeon as well as S-shaped laparoscopic instruments placed through the trocar when laparoscopic instrument-trocar units are placed through the umbilicus. In order to facilitate retraction of intra-abdominal structures during a laparoscopic procedure, an angulated needle and thread with either one- or two sharp ends is provided. Alternatively, an inflatable unit having at least one generally C-shaped trocar incorporated within the unit's walls can be placed through the umbilicus following a single incision. Generally S-shaped laparoscopic instruments may be placed through the generally C-shaped trocars to facilitate access to intra-abdominal structures. |
US08562639B2 |
Vascular filter having articulation region and methods of use in the ascending aorta
Apparatus and methods are provided for use in filtering emboli from a vessel such as the ascending aorta, wherein a vascular device comprises a support hoop having an articulation region connected near a distal end of an elongated member, a blood permeable sac affixed to the support hoop so that the support hoop forms a mouth of the blood permeable sac, a guide wire, and a delivery sheath. The articulation region comprises a reduced thickness region of the support hoop that prevents kinks from forming in the support hoop when the apparatus is contracted to its delivery state, and curved regions that close the mouth of the sac to prevent material escaping from the sac when the apparatus is collapsed for removal. |
US08562636B2 |
Embolization device and a method of using the same
Non-expandable space-occupying devices for treating voids within the body are disclosed. The devices can have multiple non-expandable space-occupying elements connected to a flexible leader. Methods of making and using the devices are also disclosed. |
US08562635B2 |
Device for converting a rotary motion into an oscillating motion
A device for converting a rotational movement into a rotatively oscillating movement is described comprising a drive shaft, a second, rotatively oscillating shaft, a driving mechanism, a housing, and a gearing mechanism comprising a movable lever. A sawing device is also described. |
US08562632B2 |
Shafted surgical instrument for remote access surgical procedures
An instrument for use in minimally-invasive procedures generally including a pair of coaxially arranged shafts, an end-effector at the distal ends of the shafts, and an actuator at the proximal ends of the shafts. The end-effector is in the form of a suture holder which includes a first, fixed arm at a distal end of a first, fixed outer shaft, and a second, movable arm at a distal end of a second, movable inner shaft. The fixed arm includes a u-shaped end, which defines an opening adapted to receive a portion of an elongate flexible suture material. A closure pin fixed at an end of the movable arm moves back and forth, opening and closing the opening in the u-shaped end of the fixed arm. The closure pin extends from the movable arm into a pin guide opening through one leg of the u-shaped end of the fixed arm. |
US08562631B2 |
Devices, systems and methods for meniscus repair
Described herein are meniscus suture passers for repair of the meniscus of the knee. These devices are typically suture passers that may include an elongate body having a pair of arms. One or more of the arms may be angled or bent at the distal end region relative to the long axis of the device, forming a distal-facing opening that is configured to fit meniscus tissue. One or both arms may be movable in the axial direction (e.g., the direction of the long axis of the device). The devices typically include a tissue penetrating element housed within one of the arms but configured to extend across the distal opening between the arms. Thus, a suture may be passed from a first side of the tissue to a second side. |
US08562629B2 |
Suture device having selective needle actuation and related method
Suturing instruments and methods for placing mattress stitches in soft tissue allowing the practitioner to selectively control placement of each stitch of the mattress stitch and/or place the stitch deeper into tissue by pulling tissue farther into the device are described herein. |
US08562627B2 |
Device and method for harvesting and implanting follicular units
Device and method for harvesting and implanting hair follicular units is provided. A combined harvesting and implanting tool or tool assembly provides a harvesting cannula portion detachably coupled to an implanting cannula portion. The harvesting and implanting cannula portions may be coupled by a connector that could be designed to allow for multiple uses of the tool assembly, or alternatively may be designed for single use and rendered non-functional when the implanting cannula portion of the tool is separated from the harvesting cannula portion of the tool. |
US08562623B2 |
Vaginal occlusion device
A vaginal occlusion device that prevents the leak of gas out of the vaginal cavity during a laparoscopic surgery. The vaginal occlusion device includes a shaft with a handle attached to one end and a round or oval shaped head attached to the other end. The head is adapted to be inserted into a vagina. |
US08562622B2 |
Suturing device with suturing capsule removal mechanism
A suturing assembly includes a handle and a head located distal to the handle. The handle includes an actuator coupled to a distal half of the handle. The head defines a head perimeter and includes a needle port and a capsule cavity located within the head perimeter. The needle port stores a needle that is connected with the actuator by a rod and the capsule cavity is sized to retain a suture capsule attached to a length of suture. A release mechanism is attached to the rod and located on the distal half of the handle. The needle is movable within the head perimeter to engage with the suture capsule and place the suture capsule into the needle port, and the release mechanism is operable to move the rod a distance in a proximal direction to separate the suture capsule from the needle. |
US08562621B2 |
Anterior spinal interbody fusion delivery system
A method includes providing a surgical instrument comprising a clear passageway, a first stationary finger, a first adjustable finger, and a first pull nut; inserting the first stationary finger and the first adjustable finger between two vertebrae; rotating the first pull nut with a hex drive, thereby separating the first adjustable finger from the first stationary finger and distracting the two vertebrae; removing a damaged disc from between the two vertebrae; and inserting an implant through the clear passageway and placing the implant between the two vertebrae. An apparatus includes a tray having a base, a first side wall, a second side wall, a distal end and a proximal end, and wherein the base, the first side wall, and the second side wall define a passageway; at least one first finger coupled to the distal end of the tray; at least one second finger coupled to the distal end of the tray; at least one pull nut coupled to the proximal end of the tray; and wherein rotation of the at least one pull nut adjusts a distance between the at least one first finger and the at least one second finger. |
US08562619B2 |
Injectable thermoplastic polymers for biological tissue repair
A method for filling a bone defect in a subject in need thereof is disclosed. The method includes heating a bone cement composition at a first temperature where the bone cement composition is fluidic, and delivering an effective amount of the fluidic bone cement composition at a second temperature to the bone defect thereby filling the bone defect and allowing the fluidic bone cement composition to solidify, the second temperature being sufficiently high for maintaining the bone cement composition fluidic without causing thermal necrosis. Also disclosed are systems for carrying out the method. |
US08562618B2 |
Joint arthroplasty devices and surgical tools
Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty. |
US08562609B2 |
Minimally invasive bone broach
A device for creating a cavity in a bone, said cavity having a cross-section which has a generally triangular profile having a first side generally parallel with an axis of the bone and a second side forming an acute angle with the first side, and contiguous with a pre-existing conical cavity, includes a shaft having a longitudinal axis and including a proximal portion and a distal portion, wherein the proximal portion has a larger cross section perpendicular to the longitudinal axis than the corresponding cross section of the distal portion, and a broach non-rotationally supported by the shaft and having a first cutting side supported at the acute angle relative to the longitudinal axis of the shaft, wherein the distal portion of the shaft is formed to include witness marks which when registered with an indicator after advancing the shaft facilitate selection of an appropriately sized prosthesis component. |
US08562608B2 |
Patello-femoral milling system
An orthopedic system prepares a surface of an anatomical structure to receive an orthopedic prosthesis. A method for using the same is also disclosed. The orthopedic system includes a surgical instrument and a guide. The guide includes an anterior portion and a distal portion that is at least partially elevated relative to the anterior portion. The distal portion includes at least one track that is sized to receive the surgical instrument while preparing the surface of the anatomical structure. |
US08562607B2 |
Bone treatment systems and methods
The invention provides instruments and methods for prophylactic treatment of an osteoporotic vertebral body or for treating a vertebral compression fracture (VCF). In one exemplary method, a probe system uses a high speed rotational cutter for abrading or cutting a plane within vertebral cancellous bone. Optional irrigation and aspiration sources are included in the probe system for removing abraded bone debris. In one embodiment, the high speed cutter uses a tissue-selective abrading surface that abrades or cuts bone but does not cut soft tissue. After the creation of a weakened cut plane in the bone, reduction of the fracture requires reduced forces. |
US08562603B2 |
Method for conducting electrosurgery with increased crest factor
A method for conducting electrosurgery using increased crest factors employs an electrosurgical instrument having at least one conductive element that is surrounded by an insulation layer except at a conductor edge portion of the conductive element. The conductor edge portion and insulation layer each having unique geometric shapes and composition of the parts concentrate the electrosurgical power, reduce or eliminate the production of smoke and eschar and reduce tissue damage. The outer profile of the insulation layer and conductive element are configured to facilitate the flow of electrosurgical decomposition products away from the conductor edge where they are formed. The combined effects of the electrosurgical instrument configurations enable safe use of crest factors of 5 or greater in electrosurgical procedures. |
US08562602B2 |
Multi-layer electrode ablation probe and related methods
Electric field delivery and ablation of target tissue regions, including cancerous cells and solid tumors. Methods and systems include delivering an electric field to a target tissue, and may include positioning a first electrode or plurality to at least partially define a first treatment volume in the target tissue; positioning a second electrode or plurality to at least partially define a second treatment volume, the first volume is disposed in the second volume; and establishing a first current flow extending through the first volume and a second current flow extending through the second volume. |
US08562596B2 |
Laser-assisted thermal separation of tissue
A laser-assisted method for fully or partially separating tissue such as collagen-containing tissue is provided. In one embodiment, the method pertains to a capsolurorhexis whereby the laser-assisted method is applied to the lens capsule. A light-absorbing agent is added into or onto the tissue. A light beam with a wavelength capable of being absorbed by the light absorbing agent is then directed at the tissue to cause a thermal effect at the tissue following a predetermined closed curve with the goal to avoid irregularity or potential tears in the resulting rim of the tissue. |
US08562595B2 |
Retinal regeneration
A method of retinal regeneration which improves retinal function by reversal of the degradation of the transport properties of Bruch's membrane. The method involves irradiation through the cornea of the eye to the retinal pigmented epithelium by a laser pulse or sequence of laser pulses having a pulse duration in the range of 10 ps to 20 μs and at a wavelength in the range of about 500 nm to 900 nm. The method applies a radiant exposure which results in the damaging or altering of the retinal pigmented epithelium cells in such a manner as to trigger cellular responses which improve the hydraulic conductivity of Bruch's membrane without causing irreversible damage to adjacent retinal structures and layers. |
US08562594B2 |
Offset remote center manipulator for robotic surgery
Medical, surgical, and/or robotic devices and systems often including offset remote center parallelogram manipulator linkage assemblies which constrains a position of a surgical instrument during minimally invasive robotic surgery are disclosed. The improved remote center manipulator linkage assembly advantageously enhances the range of instrument motion while at the same time reduces the overall complexity, size, and physical weight of the robotic surgical system. |
US08562592B2 |
Compound angle laparoscopic methods and devices
Methods and devices are provided for performing minimally invasive surgical procedures. In one embodiment, a surgical device is provided that include an elongate shaft having a distal portion configured to be movable between a first configuration in which the distal portion of the shaft is substantially straight or linear and a second configuration in which the distal portion of the shaft is articulated at a compound angle. The shaft's distal portion can include two articulation joints to facilitate formation of the compound angle. |
US08562588B2 |
Irreversible electroporation and tissue regeneration
A method and device are herein described to treat a target region of tissue, using at least one energy delivery device coupled to a power source and positioned in a treatment position so as to irreversibly electroporate tissue to ablate a target region, and introduce regenerative materials into a treated region. |
US08562586B2 |
Devices and systems for local delivery of inotropic agents to the epicardium
Devices and methods are provided for delivery of a positive inotropic agent to the heart of a patient in need thereof. An epicardial patch includes (i) a backing layer which is impermeable to the positive inotropic agent; and (ii) a drug release layer attached to the backing layer and including the positive inotropic agent and a polymeric membrane material. The polymeric membrane material provides controlled release of the positive inotropic agent to the epicardium to a region of the myocardium and in an amount effective to increase contractility. At least one of the backing layer or the drug release layer includes a tissue coupling portion for affixing the epicardial patch to an area of the epicardial surface. The epicardial patch is dimensioned and compliant to substantially avoid impeding myocardial functionality when affixed to the area of the epicardial surface. |
US08562585B2 |
Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention
A system and methods are described for improving the management of ischemic cardiac tissue during acute coronary syndromes. The system combines a catheter-based sub-system which allows for simultaneous balloon dilation of a coronary artery and infusion of a carefully controlled perfusate during percutaneous coronary intervention. The system allows for modulation of levels of oxygen at the time of percutaneous intervention. In addition, catheters and systems are provided for administration of fluids with modified oxygen content during an intervention that incorporate upstream flow control members to compartmentalize the perfusion of the target coronary artery and the remainder of the heart. |
US08562583B2 |
Method and assembly for fluid transfer and drug containment in an infusion system
A fluid transfer assembly, drug container, and method for enabling fluid transfer in an infusion system is taught. The assembly includes a fluid container containing an infusion fluid, and a drug container. The fluid container has at least one inlet port for receiving a medical substance from the drug container. The assembly further includes at least one fluid barrier controlling fluid passage between the drug container and the fluid container. The inlet port exhibits a first luer-lock connector, and the drug container is sealed by a cap exhibiting a second luer-lock connector for attachment to the first luer-lock connector. The fluid barrier is designed and arranged to be ruptured by an external force to allow the fluid passage. |
US08562580B2 |
Selective modification of a nonwoven surface
Improved fastening systems are described. More particularly, improved fastening systems for disposable absorbent articles are described. |
US08562579B2 |
Tampon overwrap
A packaged elongate intravaginal device has an overwrap substantially enclosing the device. The overwrap has a longitudinal overlap seam disposed generally parallel to the longitudinal axis. The seam includes one ply of overwrap material disposed at a first margin of a overwrap blank superposed on a second ply of overwrap material disposed at a second margin of the overwrap blank, opposite the first. The overwrap has a substantially continuous line of weakness that intersects a plane including the longitudinal axis of the packaged device at at least three unique locations. The line of weakness extends across the longitudinal overlap seam and includes weakness components superposed in each ply of the overlap seam, and the line of weakness is arranged and configured in a manner to permit the overwrap to remain as a unitary structure upon destruction of the line of weakness. |
US08562577B2 |
Liquid collection system and related methods
Various embodiments of a fluid collection system having multiple storage chambers are disclosed. In an exemplary embodiment, the system may include a first chamber in fluid communication with a suction source and a second chamber in fluid communication with the first chamber. The second chamber may have a volume less than a volume of the first chamber. The second chamber may also comprise an inlet port for connecting to an external tube. The system may be configured to selectively drain liquid from the second chamber into the first chamber. |
US08562576B2 |
Closed incision negative pressure wound therapy device and methods of use
A surgical tissue therapy device includes a sealant layer and a collection chamber. The sealant layer functions so as to create a sealed enclosure or space between it and the surface of a patient by forming, preferably, an airtight seal around a surgical area of skin trauma. The closed incision tissue therapy device also comprises a collection chamber, which may comprise an elongate tubular chamber with a plurality of longitudinally spaced openings. The collection chamber may be configured to be in fluid communication with the sealant layer and the area of skin trauma and functions as to distribute the negative pressure applied to a surgically closed area of skin trauma. Preferably, the pressure under the sealant layer is reduced by expanding the volume of the enclosure space and thereby decreasing the density of air molecules under the sealant layer. The collection material may comprise a material and/or a configuration that permits length changes based upon the length of the corresponding surgical wound or incision. |
US08562575B2 |
Holistic breast patch
The Holistic Breast Patch is the first known, non-pharmaceutical, effective device available which inhibits prolactin production safely and aids the relief of discomfort from breast engorgement pain by drying breast milk after pregnancy. The benefits of treatment of prolactin dependent diseases remain to be fully disclosed. It works transdermally and is comprised of a unique, approximately 1½ inch by ¾ inch natural and organic carbonyl disc housed within cotton gauze and nonstick adhesive Telfa®. It meets the Federal Drug Administration's definition of a non-significant risk device (21 CFR 812). Its use will aid in the treatment of prolactin dependent diseases and conditions and eliminate the serious risks of health complications and fatalities that have been documented by the use of prescription drugs, hormones and pharmaceuticals lacking FDA approval for this use by women. Wearing the Patch device is both easy and convenient. Using it as directed expedites the suppression of lactation, significantly reducing the duration of lactation and also alleviates pain associated with breast milk engorgement, in addition to the benefits derived from use in prolactin dependent and related disease treatment. |
US08562571B2 |
Slotted syringe
A syringe is disclosed. The syringe may include a syringe body, a first slot formed in the syringe body, a first sleeve covering the first slot, a thumb grip including a first slot guide disposed in the first slot, the thumb grip shaped to slide from a first position near the distal end of the syringe body toward a second position near the proximal end of the syringe body, and a plunger disposed in the fluid chamber of the syringe body. The plunger is configured to move towards the proximal end of the syringe body in response to pressure applied by a user to the thumb grip and includes a first plunger slot guide. |
US08562569B2 |
Surgical access device with pendent valve
A surgical access device, such as a trocar, includes a pendent valve having an elongate structure extending from a proximal end to a septum valve disposed at a distal end. In operation, the elongate structure follows the angle of the instrument to pre-position the septum valve into the path of the instrument where it is not significantly challenged during instrument insertion or manipulation. The pendant valve can be made to float at both the proximal end and the distal end of the elongate structure, to further reduce the vulnerability of the septum valve. Since the valve is less vulnerable to instrument insertion, it can be formed to minimize friction and maximize the functional range of the access device. |
US08562568B2 |
Control handle with device advancing mechanism
A catheter having an internal advancing mechanism that can advance stiffening wires or other devices, has a catheter with a catheter body, a tip section distal the catheter body, a device extending through at least the catheter body, and a control handle proximal the catheter body, where the control handle has an advancing mechanism with a threaded member, an adjustment member, and a guided member to which the device is connected, and the advancing mechanism is configured to advance and retract the device along the catheter body as controlled by a user. Each of the threaded member and the adjustment member has a generally cylindrical configuration. The threaded member has an outer surface configured with a helical guide channel. The adjustment member is configured to guide the guided member to move within the helical guide channel to advance and retract the device. The adjustment member can be rotatable over the threaded member by the user to control advancement and retraction of the device. The device may be a stiffener wire, a needle or any other device suitable for advancement and retraction in a catheter. |
US08562567B2 |
Inserter device with horizontal moving part
The invention concerns an insertion device for inserting a medical device or a part of medical device into the subcutaneous or intramuscular area of a patient. Insertion devices (also called inserter or injector) are commonly used in the medical field for inserting medical devices, such as infusion sets, sensors and the like, through the skin of a patient in a more or less automated fashion. The present application relates to an insertion device comprising—a penetrating member (50) comprising an inserter part provided with holding means (52) and transformation means (51), and a subcutaneous part comprising at least one part such as a cannula or a sensor for subcutaneous positioning in a patient, —a moving part (38) comprising guiding means (39) which guiding means (39) restrict the movement of the transformation means (52) and guide the moving part (38) in a second direction which is normally linear and different from the first direction i.e. the direction of insertion, towards the injection site, and—a stationary housing (30) comprising guiding means (32) which guiding means (32) restrict the movement of the moving part (38), wherein the moving part (38) comprises at least two guiding means (39a, 39b) completely separated from each other which guiding means during full insertion of at least part of the subcutaneous part of the penetrating member (50) each are in engagement with separate parts of the transformation means (51a, 51b) during at least part of the full insertion. |
US08562565B2 |
Battery shock absorber for a portable medical device
A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, other internal components in the housing, and a keypad external to the housing. The device includes a number of features and elements that enhance its operation, manufacturability, reliability, and user-friendliness. These features and elements include a shock absorbing element for a battery of the device, a keypad actuator layer that overlies a keypad assembly and forms a water resistant seal with the housing, and an offset element for a piezoelectric speaker that is located inside the housing. |
US08562564B2 |
Prefilled syringe jet injector
A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. An energy source is configured for biasing the plunger to produce an injecting pressure in the medicament in the fluid chamber of between about 80 and 1000 p.s.i. to jet inject the medicament from the fluid chamber through the needle to an injection site. |
US08562563B2 |
Power injector syringe clamp assembly with RFID antenna
A power injector syringe clamp assembly (300) is disclosed. This clamp assembly (300) includes a first clamp member (302) and a second clamp member (312), where at least one of these clamp members (302, 312) is movable to provide open and closed configurations for the clamp assembly (300). The clamp assembly (300) also includes at least one RFID reader antenna for communicating with at least one RFID tag (336) on a power injector syringe (330), at least when positioned within the clamp assembly (300). |
US08562561B2 |
Safety syringe with retractable rotation
A safety syringe with retractile rotation is disclosed. The plunger is capable of rapidly embedding with and positioning at the needle set, the next step of the retractile movement to retract the needle is easily processed by a user, and the needle set is firmly assembled and positioned at the open end of the barrel so as to not easily result an unpredictable phenomenon, such as deteriorating the suitability between the needle set and the barrel to result the needle set indentation and leakage when injecting from a sharp raise in temperatures, or overtightening the needle set and the barrel to result the needle and the needle set incapable of retracting in the barrel from the sharp fall of temperature. Furthermore, this invention is capable of achieving one hand operation with safety, improving environmental protection quantity, and easy use for retracting the needle. |
US08562558B2 |
Integrated medicament delivery device for use with continuous analyte sensor
An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver/hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and/or via wireless communication. |
US08562557B2 |
Small diameter dual lumen catheter
A multiple lumen catheter (110,150) having at least first and second lumens (112,114; 152,154). At least one of the first and second lumens (112,152) is generally C-shaped in cross-section, with a septum wall (120,160) dividing the first and second lumens providing a generally straight side to the C-shaped cross-section. A stylet or guide wire (130) may be disposed along the C-shaped cross-section lumen (112,152,154) having a larger diameter than one used with catheters of the same outer diameter but that have lumens of only D-shaped or circular shaped cross-sections. |
US08562555B2 |
Fluid exchange system for controlled and localized irrigation and aspiration
The control of fluid introduction into and out of body conduits such as vessels, is of great concern in medicine. As the development of more particular treatments to vessels and organs continues it is apparent that controlled introduction and removal of fluids is necessary. Fluid delivery and removal from such sites, usually referred to as irrigation and aspiration, using fluid exchange devices that control also need to be considerate of potential volume and/or pressure in a vessel or organ are described together with catheter and lumen configurations to achieve the fluid exchange. The devices include several electrically or mechanically controlled embodiments and produce both controlled and localized flow with defined volume exchange ratios for fluid management. The applications in medicine include diagnostic, therapeutic, imaging, and uses for the introduction or removal of concentrations of emboli within body cavities. |
US08562553B2 |
Compression bandage
A compression bandage shaped as an elongate rectangle is made of a textile fabric on which a hook strip is fastened along a narrow side of a small portion of a lateral face, or hook side. The fabric contains elastic filaments running in a longitudinal direction and, in a transverse direction, includes virtually inelastic supporting filaments having a spring constant in the longitudinal direction that ranges from 0.3 to 3 Newtons/cm of longitudinal stretching and a per meter length and per decimeter width of the compression bandage. Small loops made of soft filaments are interwoven and distributed uniformly over the entire area of the lateral face, or fleece side, opposite the hook strip. These small loops are oriented approximately perpendicularly to the lateral face, in size and distance from one another, and are complementary to the hooks of the hook strip for forming a releasable hook-and-loop closure. |
US08562552B1 |
Emergency quick splint
A splint is provided having a framesheet with a pocket to receive a rigid tube. The framesheet is secured about the injured limb by a plurality of dynamic closure straps. An optional traction bar having a cantilever arm and adjustable link is inserted on the end of the collapsible rigid tube, and connected to a harness that applies traction to the limb. The countertraction force is dissipated throughout the entire framesheet, eliminating externally applied pressure points against contiguous anatomy. |
US08562551B2 |
Neck brace
A neck brace (10) is disclosed which comprises two sections (12, 14) which are releasably connected to one another along a split line (18). The ring has upwardly facing surfaces (30, 76.1, 20.2) which limit tilting movement of a helmeted head in all directions. The brace further has a column (68, 70) which extends downwardly from the ring for transferring loads to the wearer's back on each side of the spine. |
US08562547B2 |
Method for debriding wounds
A method enabling relatively pain-free wound debridement is provided. The method entails double-delivering ultrasound to the wound and dissecting material to be debrided with a cutting edge. Delivering ultrasound energy via a coupling medium to an area of the wound within the vicinity of the material to be debrided and exposing the material to be debrided to ultrasound vibrations as to induce vibrations about the point of dissection, the double-delivery of ultrasound elicits an effect allowing for relatively pain-free debridement. While the effect elicited by the double-delivery is in place, the material to be debrided is dissected with a cutting edge. |
US08562545B2 |
Tissue penetration device
A tissue penetration device and method of using same. The tissue penetration device may optionally include sampling and analyzing functions, which may be integrated. An embodiment provides control of a lancet used for sampling blood. Electric field coils or solenoids may drive the lancet using electromagnetic force. Advancement and retraction of a lancet may be controlled by a feedback loop monitoring the position and velocity of the lancet embodiments of the lancet driver can be configured to follow a predetermined tissue lancing profile. Embodiments of the invention include a lancet and method for using a lancet to maintain the patency of the wound tract once the lancet has cut into the skin. |