Document Document Title
US08530681B2 Pharmaceutical compositions of O-nitro compounds
The present invention provides O-nitro compounds, pharmaceutical compositions of O-nitro compounds and methods of using O-nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.
US08530676B2 Process for producing vinylene carbonate
The present invention relates to the industrial production of vinylene carbonate (VC) by elimination of hydrogen chloride from chloroethylene glycol carbonate (CGC) with tertiary amines in the absence of relatively large amounts of additional solvent.
US08530675B2 Process for the synthesis of 4,5,6,7-tetrachloro-3′,6′-dihydroxy-2′,4′,5′,7′-tetraiodo-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (rose bengal) and related xanthenes
A new process for the manufacture of iodinated xanthenes in high purity includes a cyclization step followed by an iodination step. No extraction, chromatographic or solvent concentration steps are required, and the intermediate as well as final compounds are isolated via filtration or similar means. The process requires a single organic solvent, and the steps are completed at temperatures below 100° C. The exclusion of chloride ions, of chloride free-radicals, hypochlorite ions, or hypochlorous acid as reagents or from reagents that may generate these species in situ in the presence of oxidants, prevents undesirable impurity formation. Several new compounds have been conceived and isolated using these methods. These new compounds are also formed into new medicaments.
US08530673B2 Tetrathiafulvalene derivative, and organic film and organic transistor using the same
A tetrathiafulvalene derivative expressed by General Formula (I): General Formula (I) in General Formula (I), X represents an atom selected from a carbon atom, a sulfur atom, and a nitrogen atom, and Xs may be the same or different; provided that when X is the carbon atom or the nitrogen atom, R1 to R8 each represent one of a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, and a substituted or unsubstituted thioalkoxy group, and may be the same or different; and Y1 and Y2 each represent one of structures expressed by General Formulas (II) and (III), and may be the same or different: General Formula (II) General Formula (III).
US08530671B2 Method for preparing a material formed from arborescent-branched molecules comprising associative groups
The present invention relates to a method of preparing a material formed from arborescent-branched molecules comprising associative groups that includes the following successive steps: (a) the reaction of at least one at least trifunctional compound (A) bearing first and second functional groups with at least one bifunctional compound (B), the functional groups of which are capable of reacting with the first functional groups of the compound (A); and (b) the reaction of the compound(s) obtained in step (a) with at least one compound (C) bearing, on the one hand, at least one reactive group capable of reacting with the second functional groups of (A) and, on the other hand, at least one given associative group.
US08530668B2 Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity, and intermediate therefor
An optically active 4-phenylthiazole derivative having a thrombopoietin receptor agonist activity and a pharmaceutical composition containing the present compound as an active ingredient are created, and a platelet production regulating agent which can be orally administered is provided.Disclosed is a pharmaceutical composition containing, as an active ingredient, an optically active compound represented by the formula: wherein, R1 is a halogen atom or C1-C3 alkyloxy; R2 is C1-C8 alkyl; R3 is C1-C8 alkyl; R4 and R5 are each independently a fluorine atom or chlorine atom; R6 is C1-C3 alkyl or C1-C3 alkyloxy; * indicates that a carbon atom marked with an asterisk is an asymmetric carbon, a pharmaceutically acceptable salt thereof, or a solvate thereof.
US08530667B2 Herbicides
Compounds of formula (I) wherein the substituents are as defined in claim 1, are suitable for use as herbicides.
US08530664B2 Catalysts for the preparation of methylpyridine
Subject of the invention is a dehydrogenation catalyst for dehydrogenating methylpiperidine to methylpyridine. Subject of the invention are also methods for preparing the catalysts obtained thereby and methods, in which the catalysts are used.
US08530663B2 1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds
The invention relates to compounds of formula I: where X, HAr, a, and R1 through R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
US08530661B2 Process for the manufacture of pharmaceutically active compounds
The present invention further relates to a process for the manufacture of compound (I), wherein X is —Br or —Cl.
US08530656B2 Compositions and methods for inhibition of the JAK pathway
Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful.
US08530654B2 Crystals, amorphous substances or salts of methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl) phenyl] terephthalamic acid
Crystals, amorphous substances, salts, and hydrates of a salt of methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid having PDE4 inhibitory action are provided. These compounds are useful for treating allergic diseases such as atopic dermatitis.
US08530651B2 Process for the preparation of anagrelide and analogues
The present invention relates to a novel process for producing quinazoline compounds which are useful in therapy. More specifically, the compounds produced by the process of the invention are useful in the treatment of a number of cardiovascular diseases. The process of the invention provides 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin 2(3H)-one, more commonly known as anagrelide and its analogues in a clean and efficient manner.
US08530645B2 Method for producing amide compound
This invention relates to a process for producing an amide compound by Beckmann rearrangement of an oxime compound using a compound having at least two electron-withdrawing leaving groups as a rearrangement catalyst, the process comprising a pre-preparation step in which the rearrangement catalyst and at least a part of the oxime compound are mixed and reacted; and a rearrangement reaction step in which the oxime compound is rearranged at a temperature higher than that in the pre-preparation step.
US08530644B2 Method for removing impurities from biopolymer material
The present invention relates to a method for removing impurities from biopolymer material, e.g. polysaccharides, polypeptides or polynucleotides. More particularly, the present invention provides a method of reducing lipopolysaccharide levels in a lipopolysaccharide containing biopolymer material, comprising the successive steps of: a) providing an aqueous solution containing 0.05-50 wt. % of dissolved lipopolysaccharide-containing biopolymer material; 0.001-10 wt.% of a surfactant; 0.05-15 wt. % of solid adsorbent; and at least 50 wt. % of water; b) allowing the adsorbent to adsorb lipopolysaccharides; c) separating the solid adsorbent containing adsorbed lipopolysaccharides from the remaining aqueous solution; and d) recovering the biopolymer material containing a reduced level of lipopolysaccharide from the separated aqueous solution.
US08530640B2 Bicyclic cyclohexitol nucleic acid analogs
The present disclosure provides bicyclic cyclohexitol nucleoside analogs of formula I and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are expected to be useful for enhancing properties of oligomeric compounds including for example nuclease resistance.
US08530633B2 Development of sensitive FRET sensors and methods of using the same
Intramolecular biosensors are disclosed, including PBP-based biosensors, comprising a ligand binding domain fused to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding ligand. At least one of the donor and fluorescent moieties may be internally fused to the biosensor such that both ends of the internally fused fluorophore are fixed. In addition, methods of improving the sensitivity of terminally fused biosensors are provided. The biosensors of the invention are useful for the detection and quantification of ligands in vivo and in culture.
US08530625B2 Silk-based drug delivery system
The present invention provides for novel sustained release silk-based delivery systems. The invention further provides methods for producing such formulations. In general, a silk fibroin solution is combined with a therapeutic agent to form a silk fibroin article. The article is then treated in such a way as to alter its conformation. The change in conformation increases its crytallinity or liquid crystallinity, thus controlling the release of a therapeutic agent from the formulation. This can be accomplished as single material carriers or in a layer-by-layer fashion to load different therapeutic agents or different concentrations of these agents in each layer.
US08530617B2 Silicon-containing particle, process for producing the same, organic-polymer composition, ceramic, and process for producing the same
A process for producing silicon-containing particles having an extremely small particle diameter by a simple process without using surface-active agents or the like. The process is characterized by forming silicon-containing particles as a result of phase separation from an organic polymer, wherein the phase separation is achieved by an addition reaction, condensation reaction, ring-opening reaction, or a radical reaction of a curable silicon-containing compound or a curable composition that contains said compound, and the silicon-containing compound or the composition is maintained in a uniform liquid, fused, or dissolved phase with the organic polymer that is free of silicon and does not participate in the curing reaction of the silicon-containing compound or the composition.
US08530615B2 Process for producing polycarbonates and a coordination complex used therefor
The complex of the present invention containing an onium salt and a central Lewis acidic metal has a high catalytic activity at a high temperature for the copolymerization of an epoxide and carbon dioxide to produce a high molecular weight polycarbonate.
US08530610B2 Process for preparing a polymer polyol
The invention relates to a process for preparing a polymer polyol, comprising mixing in a reactor vessel, a base polyol, one or more ethylenically unsaturated monomers, a polymerization initiator, optionally a macromer, and optionally a chain transfer agent, and polymerizing the mixture thus obtained at a temperature of 50 to 200° C., wherein after discharging the reactor vessel content, the interior surface of the reactor vessel walls and/or any internals present in the reactor vessel are blasted with round media.
US08530607B2 Aromatic ether and alkynyl containing phthalonitriles
Compounds having the formulas below. R is an aromatic-containing group. Each M is an alkali metal. Each m is a positive integer. The value of n is a positive integer. The value p is 0 or 1. If p is 0 then n is 1. A thermoset made by curing a composition containing the below phthalonitrile monomers. A method of reacting a diphenyl acetylene compound with an excess of an aromatic diol in the presence of an alkali metal carbonate to form the above oligomer. A method of reacting a phenoxyphthalonitrile with an acetylene compound to form the phthalonitrile monomer below.
US08530605B2 Poly(arylene sulfide) and production process thereof
The invention provides a production process of a poly(arylene sulfide), comprising a polymerization step of subjecting at least one sulfur source selected from the group consisting of alkali metal sulfides and alkali metal hydrosulfides and a dihalo-aromatic compound to a polymerization reaction in an organic amide solvent; a reaction step of adding a hydroxyl group-containing organic compound containing no bonded halogen atom in a proportion of 0.001 to 20 mol per 100 mol of the charged sulfur source into the polymerization reaction system containing the organic amide solvent and a formed polymer after the polymerization step to cause the formed polymer to react with the hydroxyl group-containing organic compound; and a collecting step of collecting a polymer from the polymerization reaction system after the reaction step, and the poly(arylene sulfide).
US08530597B2 High molecular weight compact structured polymers, methods of making and using
A structured water soluble polymer produced by polymerization of amine-containing monomers or pre-formed polymers is described. Various structured polymers are prepared and characterized. The structured polymers are particularly valued in the papermaking industry.
US08530596B2 Polymer for forming insulating film, composition for forming insulating film, insulating film, and electronic device having same
A polymer and composition useful in forming an insulating film provided with a low permittivity, a high heat resistance, and a high mechanical strength and an insulating film obtained from these and an electronic device having the same are provided. The polymer for forming an insulating film according to the present invention is characterized by being obtained by polymerizing a reactive compound represented by Formula (1). The insulating film according to the present invention is formed using a composition for forming an insulating film including that polymer, has molecular spaces having an average space size of 0.7 nm to 5 nm, and has a permittivity of 2.3 or less. The electronic device according to the present invention has the insulating film. (wherein R1, R2, and R3 are the same or different from each other and respectively represent an organic group having a ring structure; X and Y are the same or different from each other and respectively represent an aromatic organic group having a reactive group; and n represents 0 or 1).
US08530594B2 Copolymers of alkoxythiophene
The synthesis, characterization, optical and electrochemical properties of a regioregular copolymer, poly(3-octylthiophene-2,5-diyl-co-3-decyloxythiophene-2,5-diyl) (POT-co-DOT), and an alternating regioregular copolymer poly{(9,9-dioctylfluorene)-2,7-diyl-alt-[4,7-bis(3-decyloxythien-2-yl)-2,1,3-benzothiadiazole]-5′,5″-diyl} (PF-co-DTB) is disclosed. The incorporation of 3-alkoxythiophene units onto the conjugated backbones enhances the electron-donating property of the polymer and lowers its bandgap. The fabrication and performance of photovoltaic cells with bulk heterojunction architecture based on blends of these copolymers with PCBM are also described.
US08530592B2 Catalyst components based on fulvene complexes
The present invention discloses metallic complexes based on hydroxyl-carbonyl fulvene ligands, their method of preparation and their use in the oligomerization or polymerization of ethylene and alpha-olefins.
US08530591B2 Emulsion polymers having increased chalky substrate adhesion
The present invention relates to a latex composition containing polymer particles that are polymerized in at least two stages including a first phase polymer having a relatively high molecular weight and a relatively high glass transition temperature, and a second phase polymer having a relatively low molecular weight, a relatively high glass transition temperature, and polymerized from constituent monomers that include a crosslinkable monomer. Paint compositions and architectural coatings containing the latex composition according to the invention are also described herein, as well as substrates coated therewith.
US08530590B2 Soft silicone materials for ophthalmic applications
Described herein are silicone fluids and silicone materials that posses high glass transition temperatures (Tgs) when compared to conventional silicone materials. In one embodiment, an increased Tg allows the formation of objects and materials by cryogenic lathing. The fluids and materials can be formed by curing silicone fluid with a cross-linker mixture comprising a cross-linker and a monofunctional hydride compound. Upon formation, the silicone materials can be extracted over long periods of time without loss of optical quality. The silicone materials can be sufficiently soft allowing folding and insertion through small incisions in the eye. Additionally, methods of forming optical silicone materials, lenses and silicone materials in general are also disclosed. In one embodiment, the method of forming a silicone based lens using cryogenic lathing techniques is described.
US08530585B2 Crosslinker, crosslinked polymer material, and production method of the crosslinked polymer material
The present invention provides a crosslinker used for crosslinking a polymer material having, in the molecule thereof, a multiple bond reactable with a nitrile oxide, the crosslinker including a bifunctional nitrile oxide having an aromatic nitrile oxide derivative structure in which one hydrogen atom of an aromatic ring is substituted with a nitrile oxide group and all hydrogen atoms at an ortho-position of the nitrile oxide group are substituted with a substituent other than a nitrile oxide group, wherein two such aromatic nitrile oxide derivative structures are bonded to either two oxy groups of a di-oxy structure having the two oxy groups or two carbonyl groups of a di-carbonyl structure having the two carbonyl groups.
US08530577B2 Compatibilized polypropylene heterophasic copolymer and polylactic acid blends for injection molding applications
Injection molded articles and process of forming the same are described herein. The processes generally include providing a polyolefin including one or more propylene heterophasic copolymers, the polyolefin having an ethylene content of at least 10 wt. % based on the total weight of the polyolefin; contacting the polyolefin with a polylactic acid and a reactive modifier to form a compatiblized polymeric blend, wherein the reactive modifier is produced by contacting a polypropylene, a multifunctional acrylate comonomer, and an initiator under conditions suitable for the formation of a glycidyl methacrylate grafted polypropylene (PP-g-GMA) having a grafting yield in a range from 1 wt. % to 15 wt. %; and injection molding the compatibilized polymeric blend into an article.
US08530574B2 Aqueous polymer dispersion and use thereof as binder for coating substrates
The present invention provides aqueous finely divided polymer dispersions which at low temperatures are film-forming, exhibit good blocking resistance in a formulation, even at elevated temperatures, and display a low foam tendency, processes for preparing them, and their use as binders for coating substrates.
US08530568B2 Flowable polyamides with hyperbranched polyesters/polycarbonates
Thermoplastic molding compositions, comprising A) from 10 to 99% by weight of at least one thermoplastic polyamide, B) from 0.01 to 50% by weight of B1) at least one highly branched or hyperbranched polycarbonate with an OH number of from 1 to 600 mg KOH/g of polycarbonate (to DIN 53240, Part 2), or B2) at least one highly branched or hyperbranched polyester of AxBy type, where x is at least 1.1 and y is at least 2.1, or a mixture of these, C) from 0 to 60% by weight of other additives, where the total of the percentages by weight of components A) to C) is 100%.
US08530561B2 Nonmetal material modified thermoplastic resin composite and a method for preparing products using said composite
The invention relates to nonmetal material modified thermoplastic resin composite, comprising the following materials by weight percentages: 50-70% of filling, 25-40% of polypropylene, 3-6% of maleic anhydride modified polypropylene, 1-3% of titanium dioxide and 1-2% antioxidant. Said filling has been modified by stearic acid. The invention also provides a method for producing products like sanitary wares, hardware of sanitary wares, outdoor products, decorative pipes of external walls and decorations of public scenes using the nonmetal material modified thermoplastic resin composite. The raw materials are widely available and the preparation does not require long-time burning with high energy consumption, thus possessing the advantages such as low energy consumption, high mechanical automation degree, low labor intensity, and high yield, which is applicable to industrial mass production. The invented nonmetal material modified thermoplastic resin composite is applicable to the production of sanitary wares, hardware of sanitary wares, outdoor products, decorative pipes of external walls and decorations of public scenes.
US08530554B1 Precursors for the polymer-assisted deposition of films
A polymer assisted deposition process for deposition of metal oxide films is presented. The process includes solutions of one or more metal precursor and soluble polymers having binding properties for the one or more metal precursor. After a coating operation, the resultant coating is heated at high temperatures to yield metal oxide films. Such films can be epitaxial in structure and can be of optical quality. The process can be organic solvent-free.
US08530553B2 Binder composition for spray
A binder composition for spray used for interior materials is disclosed to provide glass wool or rock wool with an adhesive force by simultaneously spraying two solutions onto the glass wool or rock wool so that the glass wool or rock wool is adhered to steel or concrete to enhance effects of heat insulation and sound insulation. The binder composition contains a first solution of 200 to 400 parts by weight consisting of polyvinyl alcohol, preservative, antifoaming agent and purified water, and a second solution of 100 parts by weight consisting of boric acid, basic compound, glycerin and purified water.
US08530552B1 Poly(phenylene ether) composition, article, and method
A composition includes specific amounts of poly(phenylene ether), polymerized styrene residue, and polymerized acrylonitrile residue. The composition can be prepared using a recycled homopolystyrene that includes an acrylonitrile copolymer as an impurity. The composition largely preserves the desirable properties of a corresponding composition prepared from virgin resins without requiring chemical compatibilization of the poly(phenylene ether) and the acrylonitrile copolymer.
US08530551B2 Flame-retardant impact-modified battery boxes based on polycarbonate I
Battery box comprising compositions containing A) 70.0 to 90.0 parts by weight of linear and/or branched aromatic polycarbonate and/or aromatic polyester carbonate, B) 6.0 to 15.0 parts by weight of at least one graft polymer, C) 2.0 to 15.0 parts by weight of one or more phosphorus compounds, D) 0 to 3.0 parts by weight of antidripping agents, E) 0 to 3.0 parts by weight of thermoplastic vinyl (co)polymer (E.1) and/or polyalkylene terephthalate (E.2), and F) 0 to 20.0 parts by weight of further additives, wherein the compositions are optionally free from rubber-free polyalkyl(alkyl)acrylate.
US08530547B2 Chloroprene rubber composition and its application
To provide a chloroprene rubber composition with which a vulcanized rubber having further improved heat resistance without impairing mechanical properties, the compression set and the tension fatigue can be obtained, and a rubber member for an automobile, a hose, a rubber molded article and a rubber vibration insulator comprising the vulcanized rubber.A chloroprene rubber composition, which comprises 100 parts by mass of at least one chloroprene rubber selected from the group consisting of a xanthogen-modified chloroprene rubber and a mercaptan-modified chloroprene rubber, and from 15 to 200 parts by mass of carbon black having a number average particle size of from 70 nm to 600 nm and having a DBP oil absorption of from 15 ml/100 g to 60 ml/100 g by oil absorption method A of JIS K6221.
US08530546B2 Curable composition comprising inorganic oxide microparticles that are surface-modified with maleimide groups
This invention is drawn to a curable composition that has excellent smoothness when a plastic substrate is coated therewith. Also disclosed are active energy beam curable compositions, such as actinically curable compositions, that can be cured without using a photopolymerization initiator, or with the use of a small amount thereof. This object is achieved by the presence of surface treated inorganic oxide microparticles. Such particles are obtained by reacting an alkoxysilane compound (a1) represented by the Formula (1) below and inorganic oxide microparticles (a2) in the presence of water and an organic solvent: (P—SiO3/2)1-a(P—Si(R0)O2/2)a(O1/2R3)z (1) in which P denotes a maleimide containing group, R3 denotes a hydrogen atom or a monovalent organic group, R0 denotes a monovalent organic group, a is 0 or a positive number and satisfies 0≦a <1, and z is a positive number and satisfies 0.1 ≦z ≦2.
US08530537B2 Black photosensitive resin composition and light blocking layer using the same
Disclosed are a black photosensitive resin composition that includes (A) an organic binder resin, (B) a reactive unsaturated compound, (C) a photopolymerization initiator, (D) a black pigment including carbon black and a silver-tin-containing alloy, and (E) a solvent, and a light blocking layer using the same.
US08530534B2 Trimerization catalysts from sterically hindered salts
The present invention provides trimerization catalyst compositions having a sterically hindered carboxylate salt and methods to produce a polyisocyanurate/-polyurethane foam using such trimerization catalyst compositions.
US08530533B2 Water-blown rigid foams for the insulation of liquefied natural gas tanks
The present invention relates to a rigid polyurethane foam comprising reinforcing materials which can be obtained by mixing (a) isocyanates which have a viscosity at 25° C. of less than 500 mPas with (b) compounds having groups which are reactive toward isocyanates, (c) blowing agents comprising water, (d) catalysts and, if appropriate, (e) further additives to form a reaction mixture and applying the reaction mixture to a reinforcing material, wherein the compounds (b) having groups which are reactive toward isocyanates comprise a polyetherol (b1) having a functionality of 4 or more and a viscosity at 25° C. of 10 000 mPas or less and a polyetherol (b2) having a functionality of 3 or less and a viscosity at 25° C. of 500 mPas or less. The present invention further relates to a process for producing such rigid polyurethane foams and the use of the rigid polyurethane foams for the insulation of liquefied natural gas tanks.
US08530532B2 Hydrogel contact lenses having improved wettability
The present invention relates to a hydrogel contact lens having improved wettability, and particularly to a hydrogel contact lens of a complex membrane having an IPN (interpenetrating polymer network) intra structure, which is prepared by crosslinking composition for a contact lens comprising, as a main ingredient, an acryl monomer and an oligosaccharide and optionally a silicone compound. Due to the presence of an oligosaccharide in a contact lens herein, tensile strength and wettability can be maximized to provide a superior wearing feeling and maintain wettability even after a long-term storage in a care solution such as a washing solution, a storage solution and a protein-removing solution.
US08530531B2 Method for the recycling of polyvinyl butyral
Method for the recycling of polyvinyl butyral based on obtaining recycled polyvinyl butyral (PVB) from laminated glass which is shattered and the polyvinyl butyral (PVB) is separated. The sheet obtained is cut into pieces and cleaned to eliminate dirt and foreign matter. The solid state PVB is subjected to a first polyvinyl butyral (PVB) purification stage with a chemical treatment with a first reagent and a final chemical treatment with a second reagent. The obtained purified polyvinyl butyral is suitable to be used in the manufacture of laminated glass.
US08530527B2 Food ingredients from Stevia rebaudiana
Various ingredients and compositions are prepared from Stevia rebaudiana Bertoni plant. The compositions can be used as bulking agents, and sweeteners in foods, beverages, cosmetics and pharmaceuticals.
US08530526B2 Biobeneficial coating compositions and methods of making and using thereof
A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the composition are provided.
US08530518B2 Salts of dihydrojasmonic acid and use thereof in agriculture
A compound comprising a water soluble salt of formula (I) wherein R1 is a C1-10alkyl group; or a C2-10alkenyl group; M is a cation of valency n, provided that when R1 is a pent-2-enyl group, Mn+ is other than sodium or potassium. These salts are particularly suitable for use in agricultural formulations. The formulations may further comprise benzoic acid derivatives and/or antioxidants.
US08530516B2 Promoting cycling of ApoE4 isoform
Cycling of ApoE4 isoform is promoted in a person in need thereof by contacting the person with an effective amount of a pharmaceutically-acceptable modulator of intracellular ApoE4 transport vesicle pH.
US08530511B2 Administration of dithiolane compounds for photoprotecting the skin
Dithiolane compounds having the structural formula (I): are useful for reinforcing and/or preserving the natural antioxidant protection of the skin against oxidative stress caused, especially, by UV radiation, e.g., by increasing the level of intracellular glutathione.
US08530509B2 Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.
US08530506B2 Process for production of biphenyl derivative
The invention provides a production method of a biaryltetrazole derivative useful as an intermediate for an angiotensin II receptor antagonist.The method comprises reacting an aryltetrazole derivative with a benzene derivative, deprotecting or reducing the resulting compound and halogenating the deprotected or reduced compound.
US08530505B2 Substituted oxazolidinones and their use in the field of blood coagulation
The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
US08530501B2 Salts and crystalline forms of a factor Xa inhibitor
The present invention provides salts and crystalline forms of the compound 5-chloro-N-((1-(4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide, and pharmaceutical compositions and method of use thereof.
US08530500B2 Stable pharmaceutical omeprazole formulation for oral administration
The present invention is directed to a pharmaceutical solution or syrup formulation for oral administration comprising; omeprazole, a solubilizing agent, a sweetening agent, a flavoring agent, and an antioxidant.
US08530499B2 Glucokinase activators
Compounds of the following formula are provided for use with glucokinase: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
US08530495B2 Nalmefene hydrochloride dihydrate
The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dihydrate.
US08530491B2 Antimalarial compounds with flexible side-chains
The present invention relates to novel compounds that are inhibitors of wild type and mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum, which are useful for the treatment of malaria. It also relates to processes of making and using such compounds. The antimalarial compounds of the present invention have low toxicity to a host infected with the malarial parasite, and are potent when administered in pharmaceutical compositions.
US08530487B1 Compounds useful for treating disorders related to TRPA1
Compounds and compositions for treating disorders related to TRPA1 are described herein.
US08530486B2 Quinazolines and related heterocyclic compounds, and their therapeutic use
A compound of the formula (I) wherein X is CR1 or N; Y is CR3 or N; R1, R3, R4, R5 and R6 are independently H, F, Cl, Br, I, or a hydrocarbon group which optionally contains one or more heteroatoms; R7 is a heterocyclic group including one or more N atoms; R′ is Rx or NRyRz wherein Rx, Ry and Rz are each H or the same or different groups, including cyclic groups formed by Ry and Rz with the N atom, of up to 20 C atoms and optionally including up to 3 further heteroatoms selected from N, O and S; or a pharmaceutically acceptable salt, ester or solvate thereof.
US08530480B2 Substituted pyrimidinyl-amines as protein kinase inhibitors
The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.
US08530478B2 Piperazine derivatives used as CAV2.2 calcium channel modulators
The present invention relates to novel piperazine derivatives (I); to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.
US08530477B2 Tropane urea derivatives, preparation thereof and therapeutic application thereof as modulators of the activity of 11betaHSD1
The invention relates to tropane urea derivatives of general formula (I) and to the application thereof as modulators of the activity of 11β-hydroxysteroid dehydrogenose type 1 (11βHSD1).
US08530476B2 Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
US08530474B2 Substituted 6-(1-piperazinyl)-pyridazines as 5-HT6 receptor antagonists
The present invention is concerned with novel substituted 6-(1-piperazinyl)-pyridazines of Formula (I) wherein R1, R2, R3 and X have the meaning defined in the claims, having 5-HT6-antagonistic properties. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said novel compound as an active ingredient as well as the use of said compounds as a medicine.
US08530473B2 Tetrahydroquinoxaline urea derivatives as modulators of 11β-hydroxysteroid dehydrogenase type 1
The invention relates to a compound of the general formula (I), as defined herein which is useful in modulating the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and are useful for treating pathologies in which such modulation is beneficial, as in the case of metabolic syndrome or of noninsulin-dependent type 2 diabetes. The invention also relates to pharmaceutical preparations containing such a compound, processes for preparing and intermediates useful in the preparation of a such a compound.
US08530467B2 Benzoimidazole compounds and uses thereof
This invention generally relates to substituted benzoimidazole compounds, particularly methyl 2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-5-methyl-1H-benzo[d]imidazol-1-yl)methyl)morpholine-4-carboxylate and salts thereof. This invention also relates to pharmaceutical compositions and kits comprising such a compound, uses of such a compound (including, for example, treatment methods and medicament preparations), processes for making such a compound, and intermediates used in such processes.
US08530465B2 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof
The invention provides a series of novel 1,2-disubstituted amido-anthraquinone derivatives. Further, the invention also provides the preparation method and application of said derivatives, said application comprises: said derivatives with therapeutically effective amount are prepared into pharmaceutical compositions for inhibition of cancer cell growth, further treating cancer.
US08530461B2 Azetidine derivatives
Azetidine derivatives of which the following is exemplary and their use in the treatment of obesity, diabetes or dyslipidemia.
US08530456B2 Sonic hedgehog modulators
The present invention relates to macrocyclic small molecule inhibitors of the Sonic Hedgehog signaling pathway, syntheses thereof, and intermediates thereto. Such small molecule modulators of the Sonic Hedgehog signaling pathway are useful in the treatment of proliferative diseases (e.g., basal cell carcinoma, Gorlin syndrome, medulloblastoma, or pancreatic cancer), pulmonary diseases (e.g., interstitial pnuemonitis or interstitial pulmonary fibrosis), and developmental disorders (e.g., phocomelia or cyclopia). Novel non-natural macrocycles are provided that inhibit Sonic Hedgehog induced-protein transcription.
US08530452B2 Tricyclic boron compounds for antimicrobial therapy
Provided herein are antimicrobial tricyclic boron compounds of the following formula I: or pharmaceutically acceptable salts, complexes, or tautomers thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
US08530446B2 Oral composition containing difructose anhydride
An oral composition for increasing equol production by inner-intestinal bacteria, wherein such composition contains difructose anhydride as an active ingredient to activate the equol production function of inner-intestinal bacteria.
US08530444B2 Pharmaceutical compounds
Novel compounds and pharmaceutical compositions are provided. In one aspect of the invention the compounds may be utilized in medical practice, for example, in treatment of cancer and immune disorders.
US08530443B2 miR-150 for the treatment of blood disorders
The invention provides methods of treating certain blood related disorders, in particular, thrombocytopenia and anemia comprising increasing miR-150 expression or inhibiting miR-150 in progenitor cells respectively.
US08530441B2 Transgene delivering retrovirus targeting collagen exposed at site of tissue injury
A viral or non-viral vector particle having a modified viral surface protein wherein the viral surface protein is modified to include a targeting polypeptide including a binding region which binds to an extracellular matrix component. Such vector particles are useful in delivering genes encoding therapeutic agents to cells located at the site of an exposed extracellular matrix component.
US08530438B2 Vivo production of small interfering RNAs that mediate gene silencing
The invention provides engineered RNA precursors that when expressed in a cell are processed by the cell to produce targeted small interfering RNAs (siRNAs) that selectively silence targeted genes (by cleaving specific mRNAs) using the cell's own RNA interference (RNAi) pathway. By introducing nucleic acid molecules that encode these engineered RNA precursors into cells in vivo with appropriate regulatory sequences, expression of the engineered RNA precursors can be selectively controlled both temporally and spatially, i.e., at particular times and/or in particular tissues, organs, or cells.
US08530434B2 Nitroxide free radical synergized antineoplastic agents
Nitroxide free radicals attached to antineoplastic agents can synergize their potencies to cancer cells. This invention relates to any antineoplastic agents and their derivatives chemically attached with nitroxide free radicals, such as TEMPO and its radical derivatives. This invention also relates to precursors of such compounds, as well as the products formed from the adducts after administration.
US08530433B2 Use of icariside II in manufacture of products for preventing or treating male or female sexual dysfunction
The present invention provides the use of icariside II or extract comprising thereof in manufacture of products for preventing or treating male or female sexual dysfunction, in particular, the use for improving pathological or organical changes in erectile tissues of patients with erectile dysfunction.
US08530432B2 Methods and compositions for treating conditions
The invention relates to compositions comprising of SEQ NO: 1-244, 248-249, and any homologs, analogs, and fragments thereof. Such compositions can be used to treat, prevent, and modulate pain, inflammation, and metabolic processes in various organisms including plants and animals. Such compositions can be formulated with an acceptable pharmaceutical excipient for administration to a human or a plant. The compositions can be administered topically or for systemic use.
US08530428B2 Treating cancer with granulocyte-macrophage colony stimulating factor
Methods for treating cancer (e.g., metastatic cancer to the lung or chronic lymphocytic leukemia) in patients are described that include administrating an aerosolized granulocyte macrophage colony stimulating factor to the patients. Methods for stimulating an immune response in patients also are described.
US08530426B2 Cosmetic or dermopharmaceutical composition comprising at least one UDP glucuronosyl transferase (UGT) enzymes inducer
The invention relates to topical use of at least one UGT inducer for the preparation of a cosmetic or dermopharmaceutical composition comprising a dermatologically acceptable carrier to protect and/or enhance the state of the skin and prevent and/or treat imperfections of the skin.
US08530424B2 System and method to improve sensory function
A system and method to improve sensory functions in the hand or foot by dermal topical application of a local anaesthetic substance to adjacent skin areas, using a tailored application device or kit specially designed to fit the size and anatomical shape of the body part which is to be anesthetized. The concept is to block sensory input from the anesthetized skin area hereby inducing a functional reorganization in sensory brain cortex resulting in enhanced sensory functions in body parts adjacent to the anesthetized area with focus on the hand and sole of the foot.
US08530421B2 Isolated polypeptides used for treatment of inflammatory diseases and inhibiting cancer metastasis
The present invention relates to a polypeptide derived from a highly conserved region (HCR) I-III of an extracellular region of a CD99 and CD99 family such as CD99L2 and PBDX(or XG), which are a kind of transmembrane protein, or a fused protein thereof. The polypeptide or the fused protein thereof has an activating function of inhibiting the extravasation of white blood cells, or inhibiting the growth and/or metastasis of cancer cells. The present invention also provides a polynucleotide coding the polypeptide, a vector including same, and a transformant transformed by the vector. In addition, the present invention provides a pharmaceutical composition including the polypeptide or the fused protein thereof for preventing or treating inflammatory diseases. Further, the present invention provides a is pharmaceutical composition including the polypeptide or the fused protein thereof inhibiting the growth and/or metastasis of cancer cells, i.e., a pharmaceutical composition for preventing or treating cancer.
US08530420B2 Treatment of arthritis with parathyroid hormone
A method for treating and/or inhibiting arthritis is provided. The method includes administering an effective amount of a composition including a parathyroid hormone and a pharmaceutically acceptable carrier or salt to a subject with arthritis. Additionally, a method for inhibiting and/or rescuing terminal differentiation of cells is also provided.
US08530414B2 Antibodies to PCSK9 and uses thereof
The present invention relates to antibodies to proprotein convertase subtilisin/kexin type 9 (PCSK9), or antigen-binding fragments thereof, compositions comprising such PCSK9 antibodies or antigen-binding fragments, and methods of using the same for the treatment of hyperlipidemia or hypercholesterolemia.
US08530412B2 Ejection liquid, ejection method, method of making droplets from liquid, cartridge and ejection device
The present invention provides a liquid composition, as an ejection liquid used for stably ejecting liquid droplets, including at least one kind of a protein and a peptide, and a compound having a betaine skeleton by application of thermal energy to the liquid; a method of making droplets form the liquid; and an ejection method and an ejection device suitable for utilizing protein liquid droplets. By adding a compound having a betaine skeleton to an aqueous solution of at least one kind of a protein and a peptide, the liquid composition is improved in stability for ejection by application of thermal energy. Further, a surfactant may be further added to the liquid composition containing the compound having a betaine skeleton, and in this case the effect of stable ejection can be obtained.
US08530410B2 Method for treating a keloid with a botulinum toxin
Methods for treating melanin related afflictions by local administration of a Clostridial toxin, such as a botulinum toxin, to a patient with a melanin related affliction.
US08530403B2 Solidification matrix using a maleic-containing terpolymer binding agent
A solidification matrix includes a maleic-containing terpolymer, sodium carbonate, and water. The maleic-containing terpolymer, sodium carbonate, and water interact to form a hydrate solid. The solidification matrix may be used, for example, in a solid detergent composition.
US08530402B2 Cleaning solvent with nanofabricated particles
A cleaning apparatus comprises a container configured to hold an article to be cleaned, a cleaning solvent dispenser configured to supply a cleaning solvent to the container, an energy generator configured to provide thermal energy to an interior of the container; and a control device in communication with the energy generator and configured to select thermal energy sufficient to sublimate the particles. The cleaning solvent comprises a solvent and nanofabricated particles dispersed therein. The control device controls the energy generator to provide thermal energy to the cleaning solvent in container in which the article is submerged in order to cause sublimation of the particles.
US08530400B2 Maintenance liquid for inkjet printers
Provided is a maintenance liquid for inkjet printers, which comprises at least one of glycol ethers and glycol esters represented by the following general formulas (1) to (3), and 45 to 10 mg/L of dissolved oxygen: R1CO(OR2)xOR3  General formula (1) R4CO(OR5)YOCOR6  General formula (2) R7(OR8)ZOR9  General formula (3) wherein R2, R5, and R8 each independently represent an ethylene group or a propylene group, R1, R3, R4, and R6 each independently represent an alkyl group having 1 to 4 carbon atoms, R7 and R9 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, and X, Y, and Z each independently represent an integer of 1 to 4.
US08530398B2 Aqueous hair cleansing agent
The aqueous hair cleansing agent of the present invention contains components (A), (B), (C), and (D) below: (A) a sulfate type anionic surfactant represented by the general formula (1) below R1O(CH2CH2O)nSO3M  (1); (B) a polyoxypropylene alkyl ether type nonionic surfactant represented by the general formula (2) below R2O(CH2CH(CH3)O)mH  (2); (C) a monoalkyl glyceryl ether or monoalkenyl glyceryl ether type nonionic surfactant having an alkyl group or alkenyl group having 4 to 12 carbon atoms; and (D) an alkylhydroxysulfobetaine type amphoteric surfactant represented by the general formula (3) below the mass ratio of components (B) and (D) being (B)/(D) =3/2 to 1/4.
US08530393B2 Methods to characterize fracture plugging efficiency for drilling fluids
Of the many compositions and methods provided herein, one method includes providing a drilling fluid comprising a base drilling fluid and a plurality of particulates, wherein the base drilling fluid without the particulates is characterized by N1(B) and wherein the base drilling fluid with the particulates is characterized by N1(A); and adjusting a concentration of the particulates in the drilling fluid by comparing the value of ΔN1(F) to ΔN1(P) so that ΔN1(F)≧ΔN1(P), wherein ΔN1(F)=|N1(A)|−|N1(B)|.
US08530390B2 Mechanical decoupling in high-temperature superconducting tapes
A novel method and structure for creating a high-temperature superconducting tape. The concept of the invention is to use a conductor insulation which not only electrically insulates the conductors of the coil windings from each other, but also mechanically insulates them from the much stronger encapsulant. The insulation material mechanically decouples the conductor from the encapsulant at the boundary between them, thereby preventing damage as a result of thermal and electromagnetic shearing forces. The proposed structure allows the encapsulant to continue performing its functions of preventing coarse motion and stabilizing the coil as a whole, while allowing fine relative displacements of individual coil windings caused by radial stress gradients.
US08530385B2 Herbicidal formulations for combinations of dimethylamine and potassium salts of glyphosate
A high strength herbicidal composition including: water; glyphosate, predominantly in the form of a combination of dimethylamine salt and potassium salt, in solution in the water in an amount of about 350 grams or greater of acid equivalent per liter of the composition, wherein the composition is formulated to include dimethylamine in an amount to form a salt with about 5% or greater, by weight, of total glyphosate and to include potassium in an amount to form a salt with a percentage of total glyphosate so that the combined sum of glyphosate in dimethylamine and potassium salts is at least 45% of total glyphosate; and optionally, one or more surfactants and/or one or more humectants.
US08530381B2 Active compound combinations
The invention relates to active compound combinations, in particular within a composition, which comprises (A) an amidine compound of formula (I) and a further fungicidally (B-1), insecticidally (B-2) active or plant growth regulating compound (B-3). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or reducing the mycotoxin contamination of plant or plant parts, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed.
US08530378B2 Apparatus and method for destroying confidential medical information on labels for medicines
The present disclosure provides a microwaveable information destruction apparatus for rendering unreadable indicia printed on a label. In various embodiments the apparatus comprises an attachable information destruction strip structured and operable to be adhered to a substrate having disposed thereon a thermally responsive label with indicia printed thereon and/or the thermally responsive label. The information destruction is attachable such that the information destruction strip is in a thermally conductive relationship with the thermally responsive label. The information destruction strip is sized to cover at least the indicia printed on the thermally responsive label. Additionally, the information destruction strip comprises a microwave activated material operable to generate heat when exposed to microwave energy. The generated heat is of sufficient intensity to heat the thermally responsive label to a temperature sufficient to cause the thermally responsive label to react and render the indicia unreadable.
US08530374B2 Catalyst body for production of brush-shaped carbon nanostructure
It is intended to highly efficiently produce a high-density brush shaped carbon nanostructure useful in the production of CNT assembly, such as rope-shaped CNTs, and provide a catalyst body for production of brush-shaped carbon nanostructure that enables the production. The catalyst body for production of brush-shaped carbon nanostructure is one comprising a substrate (32), an aggregation suppressive layer (34) superimposed on a surface thereof and a catalyst layer superimposed on the aggregation suppressive layer (34). The catalyst layer is a catalyst particle layer (44) consisting of metallic catalyst particles (42) composed mainly of a catalytic metal. The metallic catalyst particles (42) have an average particle diameter, D, satisfying the relationship 0.5 nm≦D≦80 nm, and individual particles of the metallic catalyst particles (42) have a diameter, d, falling within the range of the above average particle diameter (D). Further, there are disclosed a process for producing the catalyst body, a brush-shaped carbon nanostructure and a process for producing the same.
US08530373B2 Catalyst and process for the manufacture of ultra-low sulfur distillate product
Described is a catalyst and process useful in the hydrodesulfurization of a distillate feedstock to manufacture a low-sulfur distillate product. The catalyst comprises a calcined mixture of inorganic oxide material, a high concentration of a molybdenum component, and a high concentration of a Group VIII metal component. The mixture that is calcined to form the calcined mixture comprises molybdenum trioxide, a Group VIII metal compound, and an inorganic oxide material. The catalyst is made by mixing the aforementioned starting materials and forming therefrom an agglomerate that is calcined to yield the calcined mixture that may be used as the catalyst or catalyst precursor.
US08530372B2 Oxygen storage catalyst with decreased ceria reduction temperature
Catalysts, systems and methods for abating emissions in an exhaust stream are provided. Systems comprising a transition metal oxide stabilized oxygen storage catalyst are described. The emissions treatment system is advantageously used for the treatment of exhaust streams from lean burn engines including diesel engines and lean burn gasoline engines.
US08530365B2 Composition for improving the stability and operational performance and reducing the environmental impact of asphalt mixes
A composition useful as an additive for asphalt mixes, such as stone matrix asphalt and porous asphalt, comprising the mineral porcelanite and either an activating agent or amorphous silica, and asphalt mixes comprising the composition. The asphalt mixes are stable and meet performance requirements according to national standards. The asphalt mixes require less bitumen than fiber-stabilized mixes, and can be mixed for less time at a lower temperature. The asphalt mixes comprising the inventive composition are thus more economical and environmentally friendly than existing asphalt mixes.
US08530364B2 Material mixture for producing a fireproof material, fireproof molded body and method for the manufacturing thereof
A material mixture for producing a fireproof material, including spinel and zirconium oxide and a coarse-grained fraction with a weight fraction of greater than 50% and a fine-grained fraction, wherein the coarse-grained fraction includes coarse grains with dimensions larger than 20 μm and the fine-grained fraction includes fine grains with dimensions smaller than 20 μm.
US08530363B2 Cermets from molten metal infiltration processing
New cermets with improved properties and applications are provided. These new cermets have lower density and/or higher hardness than B4C cermet. By incorporating other new ceramics into B4C powders or as a substitute for B4C, lower densities and/or higher hardness cermets result. The ceramic powders have much finer particle size than those previously used which significantly reduces grain size of the cermet microstructure and improves the cermet properties.
US08530362B2 Leather coating compositions having improved embossability
The present invention provides aqueous compositions of one or more divalent metal crosslinked aqueous carboxylic acid group containing acrylic polymer having a Tg of ≦10° C. and one or more acrylic oligomer of a molecular weight of 20,000 or less and having a glass transition temperature (Tg) of equal to or lower than the Tg of the aqueous carboxylic acid group containing acrylic polymer. IN addition, the present invention provides methods of forming such compositions by polymerizing the aqueous carboxylic acid group containing acrylic polymer as a first stage of a multi-stage polymerization, followed by polymerizing the acrylic oligomer in the second or a subsequent stage by polymerizing the monomers in the in second or a subsequent stage in the presence of a chain transfer agent. Preferably, the compositions are used in soft feel applications to coat leather for, for example, furniture for home use and upholstery for automotive use.
US08530361B2 Process for producing silicon and oxide films from organoaminosilane precursors
A method for depositing a silicon containing film on a substrate using an organoaminosilane is described herein. The organoaminosilanes are represented by the formulas: wherein R is selected from a C1-C10 linear, branched, or cyclic, saturated or unsaturated alkyl group with or without substituents; a C5-C10 aromatic group with or without substituents, a C3-C10 heterocyclic group with or without substituents, or a silyl group in formula C with or without substituents, R1 is selected from a C3-C10 linear, branched, cyclic, saturated or unsaturated alkyl group with or without substituents; a C6-C10 aromatic group with or without substituents, a C3-C10 heterocyclic group with or without substituents, a hydrogen atom, a silyl group with substituents and wherein R and R1 in formula A can be combined into a cyclic group and R2 representing a single bond, (CH2)n chain, a ring, C3-C10 branched alkyl, SiR2, or SiH2.
US08530358B2 Vertical cavity surface emitting laser and manufacturing method thereof
The present invention discloses a manufacturing method of vertical cavity surface emitting laser. The method includes following steps: providing a substrate; forming an epitaxial layer stack including an aluminum-rich layer; forming an ion-doping mask including a ring-shaped opening; doping ions in the epitaxial layer stack through the ring-shaped opening and forming a ring-shaped ion-doped region over the aluminum-rich layer; forming an etching mask on the ion-doping mask for covering the ring-shaped opening of the ion-doping mask; etching the epitaxial layer stack through the etching mask and ion-doping mask for forming an island platform; oxidizing the aluminum-rich layer for forming a ring-shaped oxidized region. In addition, the present invention also discloses a vertical cavity surface emitting laser manufactured by the above mentioned method.
US08530356B2 Method of BARC removal in semiconductor device manufacturing
A method of removing a high molecular weight organic-comprising hard mask or BARC from a surface of a porous low k dielectric material, where a change in the dielectric constant of the low k dielectric material is less than about 5% after application of the method. The method comprises exposing the organic-comprising hard mask or BARC to nitric acid vapor which contains at least 68% by mass HNO3.
US08530354B2 Substrate processing method
The present invention provides a substrate processing method to process a substrate including at least a process layer, an intermediate layer, and a mask layer which are stacked in this order. The mask layer includes an aperture configured to expose a portion of the intermediate layer. The substrate processing method includes a material deposition step of depositing a material on a side surface of the aperture and exposing a portion of the process layer by etching the exposed portion of the intermediate layer by plasma generated from a deposit gas, and an etching step of etching the exposed portion of the process layer.
US08530352B2 Methods of patterning a material
Some embodiments include methods of forming openings. For instance, a construction may have a material over a plurality of electrically conductive lines. A plurality of annular features may be formed over the material, with the annular features crossing the lines. A patterned mask may be formed over the annular features, with the patterned mask leaving segments of the annular features exposed through a window in the patterned mask. The exposed segments of the annular features may define a plurality of openings, and such openings may be transferred into the material to form openings extending to the electrically conductive lines.
US08530350B2 Apparatuses including stair-step structures and methods of forming the same
Methods for forming semiconductor structures are disclosed, including a method that involves forming sets of conductive material and insulating material, forming a first mask over the sets, forming a first number of contact regions, forming a second mask over a first region of the sets, and removing material from of the sets in a second, exposed region laterally adjacent the first region to form a second number of contact regions. Another method includes forming first and second contact regions on portions of sets of conductive materials and insulating materials, each of the second contact regions more proximal to an underlying substrate than each of the first contact regions. Apparatuses such as memory devices including laterally adjacent first and second regions each including contact regions of a different portion of a plurality of conductive materials and related methods of forming such devices are also disclosed.
US08530348B1 Integration of non-noble DRAM electrode
A method for forming a capacitor stack is described. In some embodiments of the present invention, a first electrode structure is comprised of multiple materials. A first material is formed above the substrate. A portion of the first material is etched. A second material is formed above the first material. A portion of the second material is etched. Optionally, the first electrode structure receives an anneal treatment. A dielectric material is formed above the first electrode structure. Optionally, the dielectric material receives an anneal treatment. A second electrode material is formed above the dielectric material. Typically, the capacitor stack receives an anneal treatment.
US08530347B2 Electronic device including interconnects with a cavity therebetween and a process of forming the same
A process of forming an electronic device can include providing a first interconnect over a substrate having a primary surface, depositing a first insulating layer over the first interconnect, and patterning the first insulating layer to define an opening extending towards the first interconnect. The process can also include depositing a second insulating layer over the first insulating layer to seal the opening and form a cavity within the first opening, and forming a second interconnect over the first and second insulating layers. The cavity can be disposed between the first interconnect and the second interconnect. In another aspect, an electronic device can include a first interconnect, a first insulating layer defining a cavity, and a second interconnect. The cavity can be disposed between the first interconnect and the second interconnect, and a via may not be exposed within the cavity.
US08530345B2 Electrical contact alignment posts
An electronic apparatus and method of fabrication of the apparatus, the apparatus including a first electronic device having an interconnection surface with a first plurality of interconnection pads extending from the surface by a first distance and a second plurality of alignment posts extending from the surface by a second distance greater than the first distance, and a second electrical device having an interconnection surface with a first plurality of electrical interconnection pads, each pad arranged to contact a corresponding first electronic device interconnection surface pad upon assembly of the first electronic device interconnection surface upon the second electronic device interconnection surface, the second electronic device interconnection surface including a third plurality of alignment posts, each located to be adjacent to at least one of the first electronic device alignment posts upon assembly.
US08530342B2 Method of integrating epitaxial film onto assembly substrate
A method of growing an epitaxial film and transferring it to an assembly substrate is disclosed. The film growth and transfer are made using an epitaxy lateral overgrowth technique. The formed epitaxial film on an assembly substrate can be further processed to form devices such as solar cell, light emitting diode, and other devices and assembled into higher integration of desired applications.
US08530340B2 Epitaxial semiconductor deposition methods and structures
Methods for depositing epitaxial films such as epitaxial Ge and SiGe films. During cooling from high temperature processing to lower deposition temperatures for Ge-containing layers, Si or Ge compounds are provided to the substrate. Smooth, thin, relatively defect-free Ge or SiGe layers result. Retrograded relaxed SiGe is also provided between a relaxed, high Ge-content seed layer and an overlying strained layer.
US08530338B2 Structures of and methods for forming vertically aligned Si wire arrays
A structure consisting of vertically aligned wire arrays on a Si substrate and a method for producing such wire arrays. The wire arrays are fabricated and positioned on a substrate with an orientation and density particularly adapted for conversion of received light to energy. A patterned oxide layer is used to provide for wire arrays that exhibit narrow diameter and length distribution and provide for controlled wire position.
US08530334B2 Process of treating defects during the bonding of wafers
The invention concerns a process of preparing a thin layer to be transferred onto a substrate having a surface topology and, therefore, variations in altitude or level, in a direction perpendicular to a plane defined by the thin layer, this process comprising the formation on the thin layer of a layer of adhesive material, the thickness of which enables carrying out a plurality of polishing steps of its surface in order to eliminate any defect or void or almost any defect or void, in preparation for an assembly via a molecular kind of bonding with the substrate.
US08530330B2 Method for manufacturing a semiconductor device capable of preventing the decrease of the width of an active region
A method for manufacturing a semiconductor device that can prevent the loss of an isolation structure and that can also stably form epi-silicon layers is described. The method for manufacturing a semiconductor device includes defining trenches in a semiconductor substrate having active regions and isolation regions. The trenches are partially filled with a first insulation layer. An etch protection layer is formed on the surfaces of the trenches that are filled with the first insulation layer. A second insulation layer is filled in the trenches formed with the etch protection layer to form an isolation structure in the isolation regions of the semiconductor substrate. Finally, portions of the active regions of the semiconductor substrate are recessed such that the isolation structure has a height higher than the active regions of the semiconductor substrate.
US08530315B2 finFET with fully silicided gate
A method is provided for fabricating a finFET device. Multiple fin structures are formed over a BOX layer, and a gate stack is formed on the BOX layer. The fin structures each include a semiconductor layer and extend in a first direction, and the gate stack is formed over the fin structures and extends in a second direction. The gate stack includes dielectric and polysilicon layers. Gate spacers are formed on vertical sidewalls of the gate stack, and an epi layer is deposited over the fin structures. Ions are implanted to form source and drain regions, and the gate spacers are etched so that their upper surface is below an upper surface of the gate stack. After etching the gate spacers, silicidation is performed to fully silicide the polysilicon layer of the gate stack and to form silicide regions in an upper surface of the source and drain regions.
US08530313B2 Method of manufacturing trench MOSFET structures using three masks process
In according with the present invention, a semiconductor device is formed as follows. A contact insulation layer is deposited on the top surface of said silicon layer. A contact mask is applied and following with a dry oxide etching to remove the contact insulation layer from contact open areas. The silicon layer is implanted with a source dopant through the contact open areas and the source dopant is diffused to form source regions, thereby a source mask is saved. A dry silicon etch is carried out to form trenched source-body contacts in the contact open areas, penetrating through the source regions and extending into the body regions.
US08530310B2 Memory cell with improved retention
A method for forming a device is presented. A substrate prepared with a feature having first and second adjacent surfaces is provided. A device layer is formed on the first and second adjacent surfaces of the feature. A first portion of the device layer over the first adjacent surface includes nano-crystals, whereas a second portion of the device layer over the second adjacent surface is devoid of nano-crystals.
US08530308B2 Semiconductor integrated circuit device having improved punch-through resistance and production method thereof, semiconductor integrated circuit device including a low-voltage transistor and a high-voltage transistor
An integrated circuit device comprises a memory cell well formed with a flash memory device, first and second well of opposite conductivity types for formation of high voltage transistors, and third and fourth wells of opposite conductivity types for low voltage transistors, wherein at least one of the first and second wells and at least one of the third and fourth wells have an impurity distribution profile steeper than the memory cell well.
US08530305B2 Nanodot charge storage structures and methods
Methods, devices, and systems associated with charge storage structures in semiconductor devices are described herein. In one or more embodiments, a method of forming nanodots includes forming at least a portion of a charge storage structure over a material by reacting a single-source precursor and a reactant, where the single-source precursor includes a metal and a semiconductor.
US08530304B2 Process of forming an electronic device including a gate electrode and a gate tap
An electronic device can include a gate electrode and a gate tap that makes an unlanded contact to the gate electrode. The electronic device can further include a source region and a drain region that may include a drift region. In an embodiment, the gate electrode has a height that is greater than its width. In another embodiment, the electronic device can include gate taps that spaced apart from each other, wherein at least some of the gate taps contact the gate electrode over the channel region. In a further embodiment, at a location where the gate tap contacts the gate electrode, the gate tap is wider than the gate electrode. A variety of processes can be used to form the electronic device.
US08530294B2 Stress modulation for metal gate semiconductor device
The present disclosure provides a method of semiconductor device fabrication including removing a sacrificial gate structure formed on a substrate to provide an opening. A metal gate structure is then formed in the opening. The forming of the metal gate structure includes forming a first layer (including metal) on a gate dielectric layer, wherein the first layer includes a metal and performing a stress modulation process on the first layer. The stress modulation process may include ion implantation of a neutral species such as silicon, argon, germanium, and xenon.
US08530289B2 Method for manufacturing semiconductor device
An embodiment of the disclosed invention is a method for manufacturing a semiconductor device, which includes the steps of forming a first insulating film; performing oxygen doping treatment on the first insulating film to supply oxygen to the first insulating film; forming a source electrode, a drain electrode, and an oxide semiconductor film electrically connected to the source electrode and the drain electrode, over the first insulating film; performing heat treatment on the oxide semiconductor film to remove a hydrogen atom in the oxide semiconductor film; forming a second insulating film over the oxide semiconductor film; and forming a gate electrode in a region overlapping with the oxide semiconductor film, over the second insulating film. The manufacturing method allows the formation of a semiconductor device including an oxide semiconductor, which has stable electrical characteristics and high reliability.
US08530284B2 Method of forming a bi-directional transistor with by-pass path
In one embodiment, a transistor is formed to have a first current flow path to selectively conduct current in both directions through the transistor and to have a second current flow path to selectively conduct current in one direction.
US08530279B2 Offset gravure printing process for improved mold compound and die attach adhesive adhesion on leadframe surface using selective adhesion promoter
Placement of an encapsulation material adhesion promoter onto a semiconductor device leadframe can be performed through the use of an offset printing apparatus such as a rotogravure printing apparatus or a tampoprint printing apparatus. This can provide accurate and low-cost placement of the adhesion promoter.
US08530273B2 Method of making oxide thin film transistor array
Certain example embodiments relate to methods of making oxide thin film transistor arrays (e.g., IGZO, amorphous or polycrystalline ZnO, ZnSnO, InZnO, and/or the like), and devices incorporating the same. Blanket layers of an optional barrier layer, semiconductor, gate insulator, and/or gate metal are disposed on a substrate. These and/or other layers may be deposited on a soda lime or borosilicate substrate via low or room temperature sputtering. These layers may be later patterned and/or further processed in making a TFT array according to certain example embodiments. In certain example embodiments, all or substantially all TFT processing may take place at a low temperature, e.g., at or below 150 degrees C., until a post-annealing activation step, and the post-anneal step may take place at a relatively low temperature (e.g., 200-250 degrees C.).
US08530272B2 Method for growing zinc-oxide-based semiconductor device and method for manufacturing semiconductor light emitting device
A method which has a step of growing a thermostable-state ZnO-based single crystal on a ZnO single crystal substrate at a growth temperature that is equal to or greater than 600° C. and less than 900° C. by using a metalorganic compound containing no oxygen and water vapor based on an MOCVD method.
US08530271B2 Fullerene-doped nanostructures and methods therefor
Nanostructures are doped to set conductivity characteristics. In accordance with various example embodiments, nanostructures such as carbon nanotubes are doped with a halogenated fullerene type of dopant material. In some implementations, the dopant material is deposited from solution or by vapor deposition, and used to dope the nanotubes to increase the thermal and/or electrical conductivity of the nanotubes.
US08530268B2 Organic light-emitting display device and method of manufacturing the same
An organic light-emitting display device includes a pixel electrode and a pixel defining layer which are formed by using one mask process. A method for manufacturing the display includes thermally reflowing a remaining portion of a photo-sensitive organic film that is used as a mask to form the pixel electrode to be the pixel defining layer.
US08530263B2 Superstrate solar cell
A method of fabricating a solar cell includes forming a front contact layer over a substrate, and the front contact layer is optically transparent at specified wavelengths and electrically conductive. A first scribed area is scribed through the front contact layer to expose a portion of the substrate. A buffer layer doped with an n-type dopant is formed over the front contact layer and the first scribed area. An absorber layer doped with a p-type dopant is formed over the buffer layer. A back contact layer that is electrically conductive is formed over the absorber layer.
US08530262B2 Roll-to-roll non-vacuum deposition of transparent conductive electrodes
Methods and devices are provided for improved photovoltaic devices. Non-vacuum deposition of transparent conductive electrodes in a roll-to-roll manufacturing environment is disclosed. In one embodiment, a method is provided for forming a photovoltaic device. The method comprises processing a precursor layer in one or more steps to form a photovoltaic absorber layer; depositing a smoothing layer to fill gaps and depression in the absorber layer to reduce a roughness of the absorber layer; adding an insulating layer over the smooth layer; and forming a web-like layer of conductive material over the insulating layer. By way of nonlimiting example, the web-like layer of conductive material comprises a plurality of carbon nanotubes. In some embodiments, the absorber layer is a group IB-IIIA-VIA absorber layer.
US08530260B2 Method for attaching a first carrier device to a second carrier device and micromechanical components
A method for attaching a first carrier device to a second carrier device includes forming at least one first bond layer and/or solder layer on a first exterior of the first carrier device, a partial surface being framed by the at least one first bond layer and/or solder layer, and placing the first carrier device on the second carrier device and fixedly bonding or soldering the first carrier device to the second carrier device. The at least one first bond layer and/or solder layer includes a first cover area which is larger than a first contact area.
US08530254B2 Method of manufacturing organic electroluminescence device
A method of manufacturing an organic electroluminescence device includes forming a first organic electroluminescence layer at least on a first lower electrode, forming a first protective layer on the first organic electroluminescence layer, processing the first organic electroluminescence layer and the first protective layer, forming a second organic electroluminescence layer at least on a second lower electrode, forming a second protective layer on the second organic electroluminescence layer, and processing the second organic electroluminescence layer and the second protective layer. The second organic electroluminescence layer and the second protective layer, which have been processed by the processing the second organic electroluminescence layer and the second protective layer, cover an end portion of the first organic electroluminescence layer and an end portion of the first protective layer, which have been processed by the processing the first organic electroluminescence layer and the first protective layer.
US08530251B2 Manufacturing method of high-efficiency LED
A manufacturing method of a high-efficiency light-emitting diode (LED) is provided. A soft mold is used to transfer a microstructure or a nano-scale pattern thereon onto an imprinting material. The imprinting material is distributed all over an LED wafer; and the imprinting process may be performed through forward imprinting or reverse imprinting.
US08530242B2 Wafer process chamber leak detector
The present disclosure includes a method for monitoring leaks in a wafer process chamber. The method includes providing a wafer process chamber coupled to a gas supply by a gas supply line, wherein an indicator member is coupled to the gas supply line between the gas supply and the wafer process chamber, and a final valve is located on the gas supply line between the gas supply and the indicator member. A gas is supplied from the gas supply to the wafer process chamber through the gas supply line. A light is emitted and directed through the indicator member. The light that was directed through the indicator member is then reflected using a reflecting member. The reflected light is then received and compared to the light emitted in order to determine that the color of the indicator member has changed and a leak has been detected in the gas supply line.
US08530241B2 Hydrofluorocarbon sensing and elimination device and method
The present technology provides an illustrative hydrofluorocarbon (HFC) elimination device. An HFC sensing device is configured to detect an ambient, gaseous HFC composition. The HFC elimination device further includes a component comprising a surface that includes glass, and a heating element that is configured to heat the glass to a temperature to decompose the ambient, gaseous HFC composition in response to detection of the ambient, gaseous HFC composition by the HFC sensing device.
US08530239B2 Sample combination for NMR measurements of fats and oils
A method and apparatus for rapidly and accurately determining the fat and oil content of a sample using microwave drying and NMR analysis is disclosed. The method and apparatus incorporate a low mass, porous, hydrophilic and lipophilic sample pad that ensures that the entire sample is subjected to NMR analysis. The method and apparatus according to the invention are suitable for rapidly determining the fat and oil content of samples collected during a production process and for process or quality control.
US08530237B2 Method for culturing animal hepatocyte
Provided are a technique for easily forming a spheroid by three-dimensionally culturing hepatocytes, and a technique for forming a spheroid having a higher expression level of a transporter MRP2 playing a role of biliary excretion than that of a conventional method. In order to solve the above-described problems, the present inventors have found out a condition under which hepatocytes easily form the spheroid on a nanopillar sheet. More specifically, this is related to a concentration of Type I collagen coated onto the NP sheet. Also, they have found out a condition under which an expression level of a gene related to the excretion of the formed spheroid is improved. More specifically, after the spheroid is previously formed, a biological matrix is overlayered thereon.
US08530230B2 Multiplexed assay methods
The present invention is directed to methods for conducting multiplexed assays. The methods are particularly well suited for measuring a plurality of analytes that may be present in very different abundances. The invention also relates to systems, devices, equipment, kits and reagents for use in such methods.
US08530229B2 Amplification system with spatial separation
An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated.
US08530224B2 Marker of Streptococcus anginosus/ Streptococcus constellatus (Moac) and uses thereof
The present invention relates to nucleic acids, vectors and polypeptides that are suitable markers for detecting Streptococcus strains of the anginosus group, preferably for detecting Streptococcus anginosus and/or Streptococcus constellatus as well as for discriminating Streptococcus anginosus and/or Streptococcus constellatus from other streptococci. The present invention furthermore relates to these nucleic acids and polypeptides for use in the diagnosis and/or prognosis of infections with Streptococcus strains of the anginosus group. The present invention furthermore relates to methods utilizing these nucleic acids and polypeptides as well as to arrays and antibodies.
US08530222B2 Microorganism with ability to produce deoxy polyol dehydrogenase and use thereof
Problem: To provide a microorganism with an ability to produce deoxy polyol dehydrogenase.Means for Resolution: A microorganism belonging to genus Enterobacter with an ability to produce a dehydrogenase for deoxy polyol of the same structure at the positions C2 and C3 as that of ribitol or L-iditol. The bacterial cell IK7 of the genus Enterobacter (accession No. NITE P-271). A method for producing deoxy ketose comprising allowing a culture containing the deoxy polyol dehydrogenase obtained by the culturing of the microorganism of the invention or allowing the deoxy polyol dehydrogenase to react with a solution containing deoxy polyol of the same structure at the positions C2 and C3 as that of ribitol or L-iditol to oxidize deoxy polyol to produce the corresponding deoxy ketose and then collecting the deoxy ketose. The deoxy polyol is 1-deoxy-D-allitol, while the corresponding deoxy ketose is 1-deoxy-L-psicose. Otherwise, the deoxy polyol is L-rhamnitol, while the corresponding deoxy ketose is 1-deoxy-L-fructose.
US08530218B2 Proteases with modified pro regions
The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include modified polynucleotides that encode modified proteases, which have at least one mutation in the pro region; the modified serine proteases encoded by the modified polynucleotides; expression cassettes, DNA constructs, and vectors comprising the modified polynucleotides that encode the modified proteases; and the bacterial host cells transformed with the vectors of the invention. The methods include methods for enhancing the production of mature proteases in bacterial host cells e.g. Bacillus sp. host cells. The produced proteases find use in the industrial production of enzymes, suitable for use in various industries, including but not limited to the cleaning, animal feed and textile processing industry.
US08530217B2 Processing of peptides and proteins
The invention provides novel methionine aminopeptidase enzymes and their use.
US08530212B2 Carbene precursor compound for producing an adhesive surface on a substrate
A process for producing a substrate having an adhesive surface, which process comprises: (a) contacting the substrate with a carbene precursor, which carbene precursor is a compound of the following formula (1): whose substituent groups are defined herein, provided that when R is aryl or heteroaryl, said aryl or heteroaryl may be substituted by one, two, three, four or five groups, which groups are independently selected from various groups including -LB-WB; and (b) either: (i) when WA or WB comprises an adhesive functional group, generating a carbene reactive intermediate from the carbene precursor so that it reacts with the substrate to functionalise the surface, thereby yielding said substrate having an adhesive surface; or (ii) when WA or WB comprises a group which is a precursor of an adhesive functional group, generating a carbene reactive intermediate from the carbene precursor so that it reacts with the substrate to functionalise the surface, and (c) converting said group which is a precursor into an adhesive functional group thereby yielding said substrate having an adhesive surface. The invention further relates to carbene precursor compounds for use in the process, substrates produced by the process and to processes for preparing certain precursor compounds.
US08530207B2 Photosynthetic microorganisms comprising exogenous prokaryotic acyl-ACP thioesterases and methods for producing fatty acids
The described invention provides genetically engineered photosynthetic microorganisms expressing prokaryotic acyl-ACP thioesterases and methods of using the genetically engineered photosynthetic microorganisms for producing free fatty acids and/or fatty acid derivatives.
US08530201B2 Method of converting a biomass substrate to a fermentable sugar using a beta-glucosidase variant enzyme
The invention provides variants of the Azospirillum irakense CelA β-glucosidase that have improve β-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
US08530197B2 Method of making a paired tag library for nucleic acid sequencing
The present disclosure relates to methods and compositions for making paired tags and paired tag libraries.
US08530194B2 Oligonucleotides as temperature-sensitive inhibitors for DNA polymerases
Aspects of the invention relate to the use of novel oligonucleotides as temperature-sensitive inhibitors for thermostable DNA polymerases. Some inhibitors exhibit temperature-dependent and, in some cases, reversible inhibitory property by changing the conformation of at least a portion of the oligonucleotides from double-stranded to single stranded or in some cases vice versa in a temperature-dependent manner. Aspects also relate to the use of an the inhibitors in a hot-start PCR compositions, wherein the inhibitor may act to suppress the activity of the thermostable DNA polymerase below a desired activation temperature, Tact, and wherein the inhibitor is thermally inactivated above Tact, thus liberating the polymerase activity and initiating the DNA amplification process. Aspects further relate to a procedure for formulating the composition of a hot-start PCR reaction mixture. The hot-start PCR methods disclosed herein are generally faster, more flexible and lower in cost than existing methods.
US08530193B2 Altering enzyme balance through fermentation conditions
This present disclosure relates to methods for improved production of proteins from a cell culture, particularly to culture components and conditions that can preferentially increase the expression of proteins produced from genes under the control of xylanase gene promoter sequences. The improved methods can be used for the production of enzyme compositions with enhanced xylanase and hemicellulolytic activity.
US08530191B2 Method for preventing formation of trisulfide derivatives of polypeptides
A method for reducing or substantially preventing formation of a trisulfide derivative of a polypeptide in a liquid medium containing the polypeptide ijn question comprises stripping the liquid medium with a gas, suitably a chemically unreactive gas such as nitrogen or argon.
US08530190B1 Disulfide crosslinked glycoprotein hormone analogs, and their preparation and use
The invention relates to analogs of glycoprotein hormones with an intersubunit disulfide crosslink and their preparation and use. Corresponding DNA sequences and host cells, as well as pharmaceutical compositions are also disclosed.
US08530189B2 Sustained drug delivery system
A drug composition comprising a charged moiety coupled to a therapeutic compound is disclosed. The charged moiety is configured to interact with at least one type of component of opposite charge in a biological tissue to create an in situ depot for prolonged drug delivery. The biological tissue may be eye tissue or any tissue containing charged components.
US08530185B2 Methods and devices for microencapsulation of cells
Devices for the microencapsulation of cells include a first chamber for containing a cell-solution suspension. A plate covers one end of the first chamber. The plate has a plurality of apertures. A second chamber is provided for receiving encapsulated cells. The second chamber is separated from the first chamber by the plate. Cells from the first chamber are encapsulated by passing through the apertures in the plate and into the second chamber when pressure is applied to the cell-solution suspension.
US08530181B2 Method of screening for compounds which affect the cleavage of EphA7 byγ-secretase
The present invention provides a method of screening for compounds which affect the cleavage of EphA7 by γ-secretase. The method includes the following steps: (i) contacting a first biological composition containing γ-secretase or a biologically active fragment thereof with a second biological composition containing EphA7 in the presence and absence of a candidate compound; (ii) measuring the cleavage of the EphA7 in the presence and absence of the candidate compound; (iii) selecting those candidate compounds which affect the cleavage of the EphA7 by γ-secretase; and (iv) identifying the candidate compounds selected in step (iii) as compounds which affect the cleavage of EphA7 by γ-secretase.
US08530180B2 Method for identifying smoker or ex-smoker at risk of chronic obstructive pulmonary disease
Specific nitroprotein biomarkers may be used as prognostic and diagnostic tools for COPD. Identification of certain specific nitroprotein biomarkers allows the development of targeted therapies aimed at prevention and treatment of COPD.
US08530178B2 Hydrolase detection system with caged substrates
An enzyme detection method includes forming a caged substrate; releasing an uncaged substrate by cleaving a caging molecule from the caged substrate; and emitting a light emission from a Bioluminescence Resonance Energy Transfer luminescent nanocrystal conjugate reacting with the uncaged substrate.
US08530177B2 Chloral hydrate detection
The invention relates to an immunoassay method and kit for the indirect detection of chloral hydrate. The invention is underpinned by a novel immunogen that produces an antibody that is specific for the chloral hydrate metabolite trichloroethanol glucuronide. Detection and quantification of trichloroethanol glucuronide has important applications in clinical toxicology, drug facilitated crime, water testing and solvent exposure.
US08530170B2 Enzyme triggered redox altering chemical elimination (E-trace) immunoassay
The present invention is directed to electronic methods of detecting target analytes such that upon binding of the target analyte a shift in electrochemical potential is seen. This assay relies on the use of an electroactive moiety (“EAM”) that is attached to an electrode and comprises a self-immolative moiety, whose presence gives the EAM a first E0, and whose absence, upon irreversible cleavage gives the EAM a second E0. This difference is detected, and if such change occurs, it is an indication of the presence of a target analyte.
US08530167B2 Diagnostic and therapeutic uses of GNPTAB, GNPTG, and NAGPA in stuttering
The allelic variants or mutations in three genes: GNPTAB, GNPTG and NAGPA, that correlate with stuttering in humans, as well as the encoded mutated polypeptides and related vectors, host cells, antibodies, antibody-producing cell lines and methods of diagnosing, prognosticating and treating stuttering are provided.
US08530164B2 Method for sequencing using branching fraction of incorporatable nucleotides
Provided are methods for enhanced sequencing of nucleic acid templates. Also provided are reaction conditions that increase branching fractions during polymerization reactions. Also provided are compositions comprising modified recombinant polymerases that exhibit branching fractions that are higher than the branching fractions of the polymerases from which they were derived. Provided are compositions comprising modified recombinant polymerases that exhibit delayed translocation relative to the polymerases from which they were derived. Also provided are compositions comprising modified recombinant polymerases that exhibit increased nucleotide or nucleotide analog residence time at an active site of the polymerase. Provided are methods for generating polymerases with the aforementioned phenotypes and methods of using such polymerases to sequence a DNA template or make a DNA. Also provided are methods and nucleic acid sequencing systems for determining which labeled nucleotide is incorporated at a site during a template-dependent polymerization reaction.
US08530161B2 Detection and treatment of polycystic kidney disease
Compositions useful for examining the PKD1 gene are provided. In addition, methods for detecting mutations of the PKD1 gene, which can be associated with autosomal dominant polycystic kidney disease in humans, are provided. Methods for diagnosing a mutant PKD1 gene sequence in a subject also are provided, as are methods of treating a subject having a PKD1-associated disorder.
US08530160B2 G-protein coupled receptor kinase-5 polymorphism
The present invention is directed to compositions and methods relating to a G-protein coupled receptor kinase-5 polymorphism. The methods include, for example: detecting enhanced desensitization of the beta adrenergic receptor signaling pathway in an individual, assessing partial protection against heart failure progression in an individual, and assessing an individual's response to beta-blocker therapy. The compositions include polynucleotides or fragments thereof of a nucleotide sequence encoding for a G-protein receptor kinase-5 molecule with a thymine at amino acid position 122 and oligonucleotide primers that hybridize thereto.
US08530158B2 System and method for processing a biological sample
Systems and methods for processing a biological sample are provided herein. For example, the system can be configured to deaggregate/declump a sample before, during, and/or after sample preparation and/or sample analysis. For example, the system can include a deaggregation device/system in communication with, for example, a nucleic acid amplification process (e.g., an ePCR system). Various embodiments of the deaggregation device are provided herein. For example, in some embodiments, the deaggregation device can include a valve, a valve manifold, a conduit, a channel, or some combinations thereof.
US08530156B2 Chemically cleavable phosphoramidite linkers for sequencing by ligation
Linkers and methods for determining a nucleotide sequence of a reference oligonucleotide are provided.
US08530153B1 Lentiviral transduced dendritic cells for RNAi
The invention provides methods to prepare and use lentivirus transduced mammalian dendritic cells with altered levels of T cell co-stimulatory molecules.
US08530150B2 Detection of risk of pre-eclampsia
A method of detecting a risk of a pregnant female mammal developing pre-eclampsia or a complication linked thereto, or of a fetus of the pregnant female mammal developing a fetal or neonatal deficiency linked to maternal pre-eclampsia, comprises detecting the level of a VEGFxxxb in a sample from the pregnant female mammal at less than about 24 weeks of gestation and comparing the detected level with a reference level. A reduced level in the sample from the pregnant female mammal is indicative of a risk of the pregnant female mammal developing pre-eclampsia or a complication linked thereto or of the fetus developing the fetal or neonatal deficiency linked to maternal pre-eclampsia.
US08530143B2 Silicate-free developer compositions
A silicate-free alkaline aqueous developer composition has a pH of at least 12 and comprises a metal cation M2+ selected from barium, calcium, strontium, and zinc cations, and a chelating agent that has a complex formation constant (log K) for the metal cation of at least 3.5 and less than or equal to 4.5, and a log K for aluminum ion that is 7 or less. This developer composition can be used to process positive-working lithographic printing plate precursors to provide lithographic printing plates.
US08530141B2 Lithographic printing plate precursors
Lithographic printing plate precursors can have an imageable layer that includes a polymeric binder having an acid number of at least 30 mg KOH/g of polymer to and including 150 mg KOH/g of polymer, at least 3 weight % of recurring units derived from one or more N-alkoxymethyl (alkyl)acrylamides or alkoxymethyl (alkyl)acrylates, at least 2 weight % of recurring units having pendant 1H-tetrazole groups, and at least 10 weight % of recurring units having pendant cyano groups. The use of such polymeric binders provides good bakeability and chemical solvent resistance, especially for positive-working precursors.
US08530138B2 Salt and photoresist composition comprising the same
The present invention provides a salt represented by the formula (I): wherein Q1 and Q2 independently each represent a fluorine atom or a C1-C6 perfluoroalkyl group, L1 and L2 independently each represent a C1-C17 divalent saturated hydrocarbon group in which one or more —CH2— can be replaced by —O— or —CO—, ring W1 and ring W2 independently each represent a C3-C36 aliphatic ring, R2 is independently in each occurrence a C1-C6 alkyl group, R4 is independently in each occurrence a C1-C6 alkyl group, R3 represents a C1-C12 hydrocarbon group, t represents an integer of 0 to 2, u represents an integer of 0 to 2, and Z+ represents an organic counter ion.
US08530132B2 Toner, developer using the toner, method for preparing the toner, and image forming method and apparatus using the toner
A method for preparing a toner including toner particles is provided. The toner preparation method includes preparing a toner component liquid including at least a binder resin, a colorant and an organic solvent; mixing a resin A having a solubility of less than 2.0 g/100 g in water having a pH of 3.0 at 25° C. while having a solubility of not less than 2.0 g/100 g, a basic material, and water to prepare an aqueous phase liquid, in which the resin A is dissolved; forming droplets of the toner component liquid in the aqueous phase liquid; and removing the organic solvent from the droplets of the toner component liquid to prepare the toner particles.
US08530127B2 Process for preparing polymerized toner
A process for preparing toner and a polymerized toner prepared thereby are provided. The process for preparing toner comprises: forming an aqueous dispersion medium comprising calcium phosphate; forming a monomer mixture of a polymer charge control agent having weight average molecular weight of about 10,000 to 20,000, pigment, and a monomer for a binder resin; dispersing the monomer mixture in the aqueous dispersion in the form of droplets; and suspension-polymerizing the monomer mixture dispersed in the form of droplets, wherein about 2 to 6 parts by weight of the calcium phosphate and about 0.6 to 10 parts by weight of the charge control agent are used, on the basis of 100 parts by weight of the monomer mixture.
US08530126B2 Large particle toner
Toners are provided. In one aspect a toner comprises, particles of at least one toner resin having particle diameters greater than about 20 microns, a first particulate addenda on the toner particles having a BET surface area of less than 60 m2/g of the toner particle; and a second particulate addenda on the toner particles having a BET surface of more than 120 m2/g.
US08530123B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus
The invention provides an electrophotographic photoreceptor for use in an image-forming apparatus comprising a charging unit which charges an electrophotographic photoreceptor, an exposure unit which exposes the charged electrophotographic photoreceptor to light to form an electrostatic latent image on the electrophotographic photoreceptor, and a developing unit which develops the electrostatic latent image, wherein the electrophotographic photoreceptor comprises a conductive substrate and a photosensitive layer and the photosensitive layer contains a compound represented by the following formula (1).
US08530118B2 Multiphoton curing to provide encapsulated optical elements
Methods of fabricating optical elements that are encapsulated in monolithic matrices. The present invention is based, at least in one aspect, upon the concept of using multiphoton, multi-step photocuring to fabricate encapsulated optical element(s) within a body of a photopolymerizable composition. Imagewise, multiphoton polymerization techniques are used to form the optical element. The body surrounding the optical element is also photohardened by blanket irradiation and/or thermal curing to help form an encapsulating structure. In addition, the composition also incorporates one or more other, non-diffusing binder components that may be thermosetting or thermoplastic. The end result is an encapsulated structure with good hardness, durability, dimensional stability, resilience, and toughness.
US08530113B2 Electrode catalyst for fuel cell comprising palladium and iridium, method of preparing electrode catalyst, and fuel cell using electrode catalyst
Non-platinum (Pt) electrode catalysts for fuel cells, methods of manufacturing the same, and fuel cells including the non-Pt electrode catalysts. Each of the non-Pt electrode catalysts for fuel cells includes at least palladium (Pd) and iridium (Ir), and further includes a metal, oxide of the metal, or mixture thereof for compensating for the activity of Pd and Ir.
US08530112B2 Electricity-generation device
An electricity generation device includes: a tubular fuel cell having an electrolyte layer sandwiched between inside and outside electrodes to which a fuel gas is supplied, the fuel cell having an interior formed as an inside channel for the fuel gas; a cover pipe arranged around the fuel cell with a gap provided between the outside electrode and the cover pipe; a connecting member connecting the fuel cell and the cover pipe to each other and permitting an outside channel for the fuel gas to be formed around the fuel cell by making use of the gap; and a fuel gas pipe connected to each of opposite ends of the cover pipe and forming a flow path for the fuel gas in cooperation with the cover pipe.
US08530111B2 Fuel cell
A fuel cell is disclosed. The fuel cell can include a membrane electrode assembly (MEA), converting a chemical energy to an electrical energy; a first end plate, stacked on one surface of the MEA and formed with a first coupling hole; a second end plate, stacked on the other surface of the MEA; and a protrusion, formed on the second end plate such that the protrusion penetrates the first coupling hole and an end part of the protrusion protrudes a surface of the first end plate, and the end part being transformed such that the end part couples the first end plate and the second end plate. With the present invention, the fuel cell can reduce contact resistance between elements and its overall size and prevent a leak of fuel. In the manufacturing process, the end plates and the MEA can be arranged, improving reproducibility and repetition for mass production.
US08530102B2 Hydrogen generator
A hydrogen generator has a reaction chamber that contains a complex hydride capable of reacting with an aqueous acid solution to generate hydrogen. A storage chamber contains an aqueous acid solution that is supplied through a supply pipe to the reaction chamber to react with the complex hydride to generate hydrogen. The total weight of water contained in the aqueous acid solution is 0.2 times or more, but 3 times or less, than the weight of the complex hydride. A control device controls the supplying of the aqueous acid solution through the supply pipe to the reaction chamber based on a reference pressure such that the aqueous acid solution is repeatedly supplied to the reaction chamber when the reference pressure is greater than the internal pressure within the reaction chamber and not supplied to the reaction chamber when the reference pressure is less than the reaction chamber internal pressure.
US08530101B2 Anode exhaust recycle system
A fuel cell system includes a fuel cell stack including at least one fuel cell and a separator. Each fuel cell includes a cathode, an anode and an electrolyte between the cathode and the anode. The separator includes a membrane, and a housing defining an anode exhaust inlet, a recycled gas outlet and an exhaust gas outlet. The anode exhaust inlet and the recycled gas outlet are independently in fluid communication with the anode. The housing and the membrane defines at least in part a first chamber that is in fluid communication with the anode exhaust inlet, and a second chamber. In one embodiment, the membrane is an H2-gas permeable membrane, the recycled gas outlet is in fluid communication with the second chamber, and the exhaust gas outlet is in fluid communication with the first chamber. In another embodiment, the membrane is a CO2-gas permeable membrane, the recycled gas outlet is in fluid communication with the first chamber, and the exhaust gas outlet is in fluid communication with the second chamber.
US08530100B2 Method of chemical treatment of fuel cell plate surface to modify wettability of flow field channels
A method of surface treating a separator plate of a fuel cell comprises reacting the separator plate with an aqueous solution of hydrogen peroxide. The aqueous solution of hydrogen peroxide comprises one or more salts of one or more transition metals. The one or more transition metals have variable oxidation states. This method makes the surface of the separator plate hydrophilic (˜35 deg contact angle of water) and improves its electrical conductivity. The method of surface treating a separator plate (e.g., a graphite and/or graphite composite plate) of a fuel cell can further comprise a method of modifying wettability of the separator plate comprising treating the separator plate with a solution comprising one or more silanes. In another embodiment, a method of modifying wettability of a separator plate (e.g., a stainless steel separator plate) of a fuel cell comprises treating the separator plate with a solution comprising one or more silanes without a surface treating step prior to treating the separator plate with the solution comprising one or more silanes.
US08530099B2 Multifunctional sulfone/fluorinated ester solvents
Novel multifunctional sulfone/fluorinated ester compounds are described. These compounds may be useful as non-aqueous electrolyte solvents, specialty solvents, and starting materials and intermediates for synthesis of dyes, agricultural chemicals, and pharmaceuticals.
US08530095B2 Negative active material for rechargeable lithium battery, method of preparing same, and rechargeable lithium battery including same
Embodiments of the present invention are directed to negative active materials for rechargeable lithium batteries including lithium titanium oxides. The lithium titanium oxide has a full width at half maximum (FWHM) of 2θ of about 0.08054° to about 0.10067° at a (111) plane (main peak, 2θ=18.330°) as measured by XRD using a Cu Kα ray.
US08530094B2 Reduced puffing needle coke from coal tar distillate
A reduced puffing needle coke is formed, which includes a reduced nitrogen content within the coke so that the coke particles do not experience as much puffing during the formation of graphitized carbon articles produced from such coke upon heating to graphitization temperatures.
US08530090B2 Energy storage device
An energy storage device comprising an anode, electrolyte, and cathode is provided. The cathode comprises a plurality of granules comprising a support material, an active electrode metal, and a salt material, such that the cathode has a granule packing density equal to or greater than about 2 g/cc. A cathode comprising greater than about 10 volume % total metallic content in a charged state of the cathode is also provided.
US08530087B2 Secondary lithium battery
It is an object to provide a cathode for a secondary lithium battery in which adhesiveness and flexibility thereof are simultaneously achieved and the thickness thereof is made large, and the secondary lithium ion battery that has a large capacity and is excellent in safety and cycle life using the cathode.The cathode includes a current collector and a cathode mixture layer formed on the surface of the current collector. The cathode mixture layer is formed by stacking two layers one on another, each of which contains a cathode active material, a conductive material and a binder, and the cathode active material contains a lithium-containing composite oxide that forms a polyanion. Of the two layers, the binder that composes a first layer that is in contact with the current collector contains a polymer formed by polymerizing at least one of monomers consisting of a monomer derived from 1-olefin and a monomer derived from a vinyl compound; and the binder that forms a second layer formed on the first layer contains a fluorine resin.
US08530084B2 Electrode structure for non-aqueous electrolyte secondary battery, method for producing the same, and non-aqueous electrolyte secondary battery
An electrode 13 has an active material layer 12 formed on each of two whole main surfaces of a current collector 11. A part of an electrode lead 14 overlaps the electrode 13. One end face of the electrode 13 in the width direction of the electrode 13 is flush with one end face of the electrode lead 14. Joints 15 are formed at the one end of the electrode 13 in the width direction. The joints 15 join the electrode 13 and the electrode lead 14 so as to provide electrical continuity between the exposed part of the current collector 11 at the one end face of the electrode 13 in the width direction and the electrode lead 14. The joints 15 are formed, for example, by plasma welding.
US08530080B2 Nonaqueous electrolyte solution and lithium secondary battery using same
A nonaqueous electrolytic solution that provides a lithium secondary battery with excellent electrical capacity, cycling properties, storage properties and other battery characteristics and that maintains the battery characteristics for a long time; and a lithium secondary battery comprising it. A nonaqueous electrolytic solution comprising an electrolytic salt dissolved in a nonaqueous solvent, containing 0.1 to 10% by weight of an ethylene carbonate derivative represented by the general formula (I), and 0.01 to 10% by weight of (A) a triple bond-containing compound and/or (B) a pentafluorophenyloxy compound represented by the general formula (X), wherein formula (I) is: wherein R1 to R3 each independently represents a hydrogen atom, a halogen atom, an alkenyl group, an alkynyl group or an aryl group, provided that ethylene carbonate is excluded from the definition of the ethylene carbonate derivative; and wherein formula (X) is: wherein R15 represents an alkylcarbonyl group, an alkoxycarbonyl group, an aryloxycarbonyl group or an alkanesulfonyl group.
US08530079B2 Rechargeable battery
A rechargeable battery includes an electrode group with a separator, a positive electrode, and a negative electrode in a case, a cap plate for sealing the case and including a terminal hole, an electrode terminal extending through the terminal hole, and a lead tab connecting the electrode terminal to the electrode group. The lead tab includes a horizontal part connected to the electrode terminal, a first vertical part and a second vertical part spaced apart from each other and extending from the horizontal part in a vertical direction along the electrode group, and a connection part connecting the first vertical part and the second vertical part, the connection part being spaced apart from the horizontal part to define a gas outlet that overlaps an end part of the electrode group.
US08530077B2 Insulating case for secondary battery and secondary battery having the same
An insulating case for a secondary battery and a secondary battery having the same, the insulating case having opposing first and second portions. The first portion faces an electrode assembly of the secondary battery and has a first melting point. The second portion faces a cap assembly of the secondary battery and has a second melting point that is higher than the first melting point. The first melting point is approximately the contraction temperature of a separator of the electrode assembly.
US08530076B2 Protection circuit module for rechargeable battery and rechargeable battery pack including the same
A protection circuit module and a rechargeable battery pack including the PCM. The battery pack includes: an electrode assembly, which has a positive electrode plate, a separator, and a negative electrode plate; a case to house the electrode assembly and an electrolyte; and the protection circuit module. The protection circuit module includes: a protection circuit board having an inner surface that faces the electrode assembly and an opposing outer surface; and a protection circuit part mounted in a hole formed in the inner surface of the protection circuit board, such that the protection circuit board is flush with the inner surface of the protection circuit board.
US08530067B2 Battery
Provided is a battery capable of obtaining superior cycle characteristics. The battery comprises a cylindrical type spirally wound body including a spirally wound laminate of a cathode and an anode with a separator in which an electrolyte solution is impregnated. The anode includes an anode current collector, an outer anode active material layer disposed on an outer winding surface of the anode current collector and an inner anode active material layer disposed on an inner winding surface of the anode current collector. The outer anode active material layer and the inner anode active material layer include Si, Sn or a compound thereof. The capacity ratio between the outer anode active material layer and the inner anode active material layer in at least one region is within a range of 0.6 to 0.8 inclusive.
US08530065B1 Composite magnetic recording medium
A composite hard magnetic recording layer for a magnetic storage comprises a hard magnetic layer and a capping layer. The composite recording layer has a crystal structure where crystal grains include a portion within the magnetic layer and a portion within the capping layer.
US08530058B1 Oxidation resistant Pb-free solder alloys
A lead free solder consisting of a ternary eutectic composition of Sn-3.9Ag-0.7Cu with Ce in the amount of 0.5 to 2% by weight exhibits improved oxidation resistance increased ductility in comparison with other RE metals and is characterized by a homogeneous mixture of large grain CeSn3 intermetallics in a Sn beta phase. In solder applications, the joints with the solder are resistance to interfacial fracture by distributing the strain within the solder interface increasing impact resistance.
US08530055B2 Ceramic green body and method for producing the same
The ceramic green sheet is formed by molding and drying “a ceramic slurry containing a ceramic powder, an unreacted portion of an isocyanate, an unreacted portion of a polyol, a urethane resin that is produced by mixing isocyanate and polyol and serves as an organic binder, and a solvent”, the ceramic slurry being prepared by mixing the ceramic powder, the isocyanate, the polyol, and the solvent. A thin sheet-like molded body is formed by printing a molded body of a paste, which is prepared by mixing a ceramic powder, an organic binder that is a resin not containing a hydroxyl group, and a solvent, on the ceramic green sheet, and by drying the resultant. A dry shrinkage percentage of the ceramic green sheet upon forming the thin sheet-like molded body thereon can significantly be reduced.
US08530053B2 Heat-resistant composite material
A high heat-resistant composite material which comprises a polymerizable composition comprising a bi-functional epoxy compound, a tri- or more-functional epoxy compound and a polymerization initiator, wherein the polymerization initiator comprises a sodium salt or potassium salt of mono- or poly-functional carboxylic acid, and a reinforcing fiber such as a carbon fiber or a glass fiber; and a vehicle member or a construction member comprising the above heat-resistant composite material. Said composite material comprises an epoxy polymer having high heat-resistant physical properties over those of a conventional epoxy polymer as a matrix, and exhibits an extremely high retention factor of storage modulus at high temperature.
US08530051B2 High strength gear, power transmission mechanism using same, and production method for high strength gear
A high strength gear used as an element of a power transmission mechanism. The gear includes a base gear formed of an iron-based alloy subjected to carburizing or carbonitriding treatment. The base gear has an engaging surface with which an opposite gear is engaged. The engaging surface of the base gear is coated with a first diamond-like carbon film which has a hydrogen content of not more than 10 atomic % and a surface hardness ranging from 8 to 30 GPa in a nano-indentation test. Additionally, at least a part of the first diamond-like carbon film is coated with a second diamond-like carbon film which has a hydrogen content of not more than 10 atomic % and a surface hardness ranging from 50 to 90 GPa in the nano-indentation test. The second diamond-like carbon film has a surface roughness Ra ranging from 0.1 to 0.2 μm.
US08530048B2 Surface-modified particles and production method
The invention relates to surface-modified particles, more particularly inorganic-based particles having reactive surfaces, more particularly surfaces containing silane-reactive and/or siloxane-reactive groups, preferably hydroxyl-containing surfaces and/or particles comprising or consisting of metal and/or semi-metal oxides and/or hydroxides, preferably nanoparticles, which on their surface have a polysiloxane-based modifier having more particularly been reacted on their surface with a polysiloxane-based modifier, preferably with the formation of chemical bonds, more particularly covalent bonds, and also to a method of producing these surface-modified particles.
US08530045B2 Brittle polymeric film and tamper evident labels made therefrom
A process for the production of a polymeric film comprising a copolyester having an acid component and a diol component, said acid component comprising a dicarboxylic acid and a sulfomonomer containing a sulfonate group attached to the aromatic nucleus of an aromatic dicarboxylic acid, said process comprising the steps of: (i) melt-extruding a layer of said copolyester; (ii) stretching the extrudate in at least one direction; (iii) heat-setting the film by raising the temperature of the stretched film to a temperature T1 in a first heating zone such that (TM−T1 is in the range of from 5 to 30° C., and then raising the temperature of the film to a temperature T2 in a second heating zone such that (TM−T2 is in the range of from 0 to 10° C., wherein TM is the peak melting temperature of the polymeric film; wherein T2 is greater than T1; and wherein the times which a transverse section of the film spends in the first and second heating zones are defined by t1 and t2, respectively, such that the ratio of t1 to t2 is at least 2:1; and a polymeric film obtainable thereby having an ultimate tensile strength at destruction in the range of 2 to 15 kgf/mm2 in the machine direction and 2.5 to 17 kgf/mm2 in the transverse direction.
US08530044B2 Hyperbranched oligomeric phosphonates and compositions including the same
Disclosed are oligomeric phosphonates, and in particular, hyperbranched oligophosphonates, that include oligophosphonates, random or block co-oligo(phosphonate ester)s and co-oligo(phosphonate carbonate)s produced using a condensation process terminated with hydroxyl, epoxy, vinyl, vinyl ester, isopropenyl, isocyanate groups, and the like. These materials can be used as a reactive additive to other polymers, oligomers or monomer mixtures to impart flame resistance without diminishing melt processability which is important in the fabrication of polymers for many applications.
US08530043B2 Composite laminate composition
A multi-layer composite laminate composition having a substrate layer and an overlay layer that are both bonded to at least one adjacent layer in a multi-layer composite laminate composition; the substrate layer being a thermoformable material having a material formulation that includes a polycarbonate homopolymer or copolymer; the overlay layer being a thermoformable material having a material formulation that includes an ingrediant selected from the group consisting of PVC, PVC alloy, acrylic, polyurethane, acrylonitrile butadiene styrene, and combinations thereof.
US08530041B2 Transparent conductive film and touch panel
The transparent conductive film of the present invention is a transparent conductive film, comprising a transparent film substrate, and a first transparent dielectric layer, a second transparent dielectric layer and a patterned transparent conductive layer that are formed on one or both sides of the transparent film substrate in this order from the transparent film substrate side, wherein the transparent conductive layer has a thickness of 31 nm or more, the first transparent dielectric layer has a thickness of from 7 nm to 16 nm, the second transparent dielectric layer has a thickness of from 30 nm to 60 nm, and the relation n2
US08530040B2 Nestable molded articles, and related assemblies and methods
A man-made, molded article is provided. The article includes a profile including a planar wall, and an adjacent integral molded depression having a contoured wall extending downwardly from the planar wall. The contoured wall includes a bead portion, a cove portion, and a ledge between the bead and cove portions. The articles are stackable, one above another for transport, in a nestable relationship in which multiple contact zones are present between the contoured walls of an adjacently stacked pair of the molded articles. The contact zones include an arcuately extending contact interface zone between the bead exterior and interior surfaces. The depression has a substantially uniform thickness varying by no more than about +1 percent to about −11 percent in relation to a thickness of the planar wall. Related methods and assemblies are also provided.
US08530039B2 Polycrystalline complex-shaped mesoscale components
A polycrystalline mesoscale component, formed through a process including filing a mold cavity formed in a photoresist with a mold fill, is provided with an overall length L divided into multiple segments with a second segment extending from a first segment at a nonlinear angle. The first segment has a first segment height H1 and a first segment thickness T1, while the second segment has a second segment height H2 and a second segment thickness T2, with the lesser of H1 and H2 defining a minimum segment height Hmin and the lesser of T1 and T2 defining a minimum segment thickness Tmin. The resultant component has a ratio of L:Hmin:Tmin of 20-80:1:0.5-10 where Hmin is between 5 and 500 microns. In specific instances, the nonlinear angle is acute, the multiple segments are rectilinear in cross section, and a segment thickness has an edge resolution of between 0.1 and 2 microns.
US08530038B2 Panel made of a wooden material with a surface coating
A panel made of a wooden material with a surface coating has an undercoat which is applied to the wooden material and at least one lacquer coating and a functional component. There is produced a panel made of a wooden material with a low-cost surface coating which can be applied easily and is optically appealing.
US08530036B2 Hard shell bodyboard kickboard
A sports board has a hard top shell formed with a top concave shell cavity. The hard top shell has an inside surface. The hard top shell is pervious to light. A top layer of adhesive adheres to the hard top shell. A rigid foam core is formed with a top profile and a bottom profile. The top profile matches and receives the top hard shell. The top layer of adhesive adheres to a top surface of the foam core. A bottom layer of adhesive adheres to a bottom surface of the rigid foam core; and a hard bottom shell is formed with a bottom concave shell cavity. The bottom concave shell cavity is formed to fit to the bottom profile. The hard bottom shell is pervious to light.
US08530035B2 Carbon nanotube precursor
A carbon nanotube precursor includes a strip-shaped carbon nanotube array comprising a plurality of carbon nanotubes. The strip-shaped carbon nanotube array is defined by dividing a carbon nanotube array with a separating line. A length of the strip-shaped carbon nanotube array is greater than a largest width of the carbon nanotube array.
US08530033B2 External wall panel and method of coating for the same
The present invention relates to an external wall panel which is excellent in ornamental design and weather resistance and a coating method for the external wall panel. An external wall panel of the invention comprises a base panel having a three-dimensional ornamental design surface, a lower coating layer formed on the surface of the base panel, a mid-coating layer formed on the lower coating layer, a first clear layer containing beads formed on the mid-coating layer, and a second clear layer made of a transparent layer or semi-transparent layer formed on the first clear layer wherein the second clear layer has a thick film layer portion in the vicinity of a corner edge of a convex portion of the three-dimensional ornamental design surface.
US08530032B1 Disk drive housing hole seal including a conductive layer with an exposed planar surface region
There is provided a seal for covering a hole in a disk drive housing. The seal includes a conductive layer, a primary dielectric layer, and a gasket layer. The conductive layer has a covered surface region and an exposed planar surface region. The exposed planar surface region is lacking a dielectric coating disposed thereon. The primary dielectric layer includes an adhesive coating disposed between the primary dielectric layer and the covered surface region. The gasket layer includes first and second adhesive gasket layer sides and a gasket opening disposed through the gasket layer.
US08530029B2 Low thermal mass cordierite bodies and methods for making same
Disclosed are cordierite bodies having relatively low thermal mass with good mechanical strength. The porous cordierite bodies generally include a primary cordierite ceramic phase as defined herein. Also disclosed are methods for making and using the cordierite bodies.
US08530026B2 Artificial fiber for use in an artificial grass sports field
An artificial fiber for use in an artificial grass sports field is disclosed wherein, seen in a transverse sectional direction of the fiber, at least part of the fiber is provided with a stiffness-enhancing portion extending in the longitudinal direction thereof. The artificial fiber includes at least two fiber flange portions, at least one fiber flange portion forming the stiffness-enhancing portion, while at least two fiber flange portions have a uniform thickness. The improved artificial fiber is less flexible and consequently exhibits less tendency to deform to a flat orientation, but does not increase the risk of injuries to players or have an adverse effect on the playing characteristics of the field. Also disclosed is an artificial grass lawn, suitable for sports fields, having a substrate to which one or more artificial fibers of the invention are attached.
US08530024B2 Recording layer for optical information recording medium, optical information recording medium, and sputtering target
A recording layer excellent in recording property, an optical information recording medium including the recording layer, and a sputtering target for producing the recording layer. The recording layer on which recording is performed through irradiation with a laser light, contains: a Pd oxide; a Ag oxide; and an oxide of a metal X of having an absolute value of the standard free energy of oxide formation per 1 mol of oxygen that is larger than an oxide of Pd and Ag, wherein a ratio of Pd atom to a total (metal X atom+Pd atom+Ag atom) is from 10 to 60 atomic %, a ratio of Ag atom to the total is from 5 to 45 atomic %, and a ratio of Pd atom and the Ag atom to the total is 75 atomic % or less.
US08530023B2 Optical information recording medium and sputtering target for forming reflective film for optical information recording medium
Disclosed is a read-only optical information recording medium which comprises a reflective film having a reflectance suitable for use as a reflective film for an optical information recording medium (e.g., BD-ROM) and having excellent reproduction stability, and which utilizes a blue laser beam. Specifically disclosed is a read-only optical information recording medium comprising a reflective film, wherein the reflective film comprises an Al-based alloy containing at least one element selected from Si and Ge in an amount of 5 to 40 at. %.
US08530020B2 Sheet of printable business cards
A sheet of printable business cards which includes a cardstock sheet construction having a front side and a back side and a solid continuous liner sheet releasably secured with ultraremovable adhesive to and covering the back side. Continuous through-cut lines are cut through the cardstock sheet construction to the back side but not through-cut through the liner sheet; the through-cut lines defining at least in part perimeter edges of printable business cards. Portions of the back side of the cardstock sheet construction form back side surfaces of the printable business cards. Areas of the liner sheet covering back sides of all of the through-cut lines and thereby hold the printable business cards together when the sheet of printable business cards is fed through a printer or copier for a printing operation on the printable business cards. The liner sheet and the through-cut lines allow the business cards to be removed from the liner sheet and separated after the printing operation into individual printed business cards.
US08530015B2 Reinforcement of hollow profiles
A structural reinforcement comprising a hollow profile and a ribbed structure, the ribbed structure including a laminar structure of two facing sheets with a first layer of adhesive material that is foamable and located in between the two facing sheets, the ribbed structure having ribs with one or more ends and a second adhesive material that is provided over at least part of the ribs at the one or more ends to bond the ribs at the one or more ends to an interior surface of the hollow profile.
US08530014B2 Laminate
The present invention provides a laminate having an environmental cracking resistance for a fuel and a fuel impermeability and, in addition, higher in productivity. The present invention is a laminate including a chlorotrifluoroethylene copolymer layer (C) and a fluorine-free organic material layer (K), wherein the chlorotrifluoroethylene copolymer has a melt flow rate of 15.0 to 40.0 (g/10 minutes) and contains 15.0 to 25.0 mole percent of chlorotrifluoroethylene units relative to all monomer units.
US08530009B2 Liquid crystal display device including side supporting means and method of fabricating the same
A liquid crystal display device includes: a bottom frame having a horizontal portion and a vertical portion extending from an edge region of the horizontal portion; a backlight unit disposed on the horizontal portion; a liquid crystal panel on the vertical portion and over the backlight unit; a side frame combined with the bottom frame to surround the vertical portion, the side frame having a step portion; and a side supporting means on the step portion, the side supporting means contacting a side surface of the liquid crystal panel to support the liquid crystal panel, wherein the side supporting means includes a light-curable material that expands due to irradiation of a ultraviolet ray.
US08530005B2 Control of nanocrystalline cellulose film iridescence wavelength
A new method to control the iridescence color of solid nanocrystalline cellulose (NCC) films by ultrasound and high-shear (mechanical) energy input to the NCC suspension prior to film formation is provided. As the energy input to the NCC suspension increases, the resulting film color shifts from the ultraviolet region towards the infrared region of the electromagnetic spectrum; this wavelength shift lies in the opposite direction to that caused by the addition of electrolytes to NCC suspensions prior to film formation. No additives are required to achieve the changes in color; color changes can also be effected by mixing two suspensions exposed to different levels of sonication.
US08530003B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device
A polybenzoxazole precursor is represented by the following formula (1): wherein R1a to R4a, R1b to R4b, X1, Y1 and m are defined in the specification.
US08530002B1 Methods for attaching polymerizable ceragenins to water treatment membranes using silane linkages
This invention relates to methods for chemically grafting and attaching ceragenin molecules to polymer substrates; methods for synthesizing ceragenin-containing copolymers; methods for making ceragenin-modified water treatment membranes and spacers; and methods of treating contaminated water using ceragenin-modified treatment membranes and spacers. Ceragenins are synthetically produced antimicrobial peptide mimics that display broad-spectrum bactericidal activity. Alkene-functionalized ceragenins (e.g., acrylamide-functionalized ceragenins) can be attached to polyamide reverse osmosis membranes using amine-linking, amide-linking, UV-grafting, or silane-coating methods. In addition, silane-functionalized ceragenins can be directly attached to polymer surfaces that have free hydroxyls.
US08530000B2 Methods of forming charge-trapping regions
Some embodiments include methods of forming charge-trapping zones. The methods may include forming nanoparticles, transferring the nanoparticles to a liquid to form a dispersion, forming an aerosol from the dispersion, and then directing the aerosol onto a substrate to form charge-trapping centers comprising the nanoparticles. The charge-trapping zones may be incorporated into flash memory cells.
US08529998B2 Method for manufacturing molten metal plated steel strip
A gas wiping nozzle includes a primary nozzle portion and at least one secondary nozzle portion provided either or both above and below the primary nozzle portion. The secondary nozzle portion jets a gas in a direction tilted from the direction in which the primary nozzle portion jets the gas and at a lower flow rate. The gas wiping nozzle has a tip whose lower surface forms an angle of 60° or more with the steel strip. The gas jetting port of the secondary nozzle portion is displaced in the direction opposite to the steel strip at least 5 mm apart from the gas jetting port of the primary nozzle portion, and the secondary nozzle portion jets the gas so that the flow rate of the secondary gas jet comes to 10 m/s or more at the confluence with the primary gas jet from the primary nozzle portion.
US08529994B2 Growth and applications of ultralong carbon nanotubes
Ultralong carbon nanotubes can be formed by placing a secondary chamber within a reactor chamber to restrict a flow to provide a laminar flow. Inner shells can be successively extracted from multi-walled carbon nanotubes (MWNTs) such as by applying a lateral force to an elongated tubular sidewall at a location between its two ends. The extracted shells can have varying electrical and mechanical properties that can be used to create useful materials, electrical devices, and mechanical devices.
US08529993B2 Low volatility polymers for two-stage deposition processes
This invention relates to materials and processes for the preparation of high quality layers, for example for the fabrication of optical devices such as waveguides. In particular, the invention relates to the use of low volatility polymer materials for the deposition of high quality layers on large area substrates via a two-stage process, for example extrude-and-spin.
US08529987B2 In-process orientation of particles in a direct-write ink to control electrical characteristics of an electrical component being fabricated
A system for in-process orientation of particles used in direct-write inks for fabricating a component may include a device for polarizing direct-write particles in an aerosol. An outlet may direct the aerosol including the polarized direct-write particles on a substrate to form a component. An apparatus may cause the polarized direct-write particles to be aligned in a selected orientation to form the component with predetermined characteristics when deposited on the substrate.
US08529986B1 Layer acoustic wave device and method of making the same
The present invention provides a layer acoustic wave device that is formed without requiring a bonding process to attach a secondary substrate. In particular, the layer acoustic wave device is formed from a substrate, an interdigital transducer created on the substrate, a dielectric layer formed over the interdigital transducer and substrate, and at least one isolation layer formed over the dielectric layer. The at least one isolation layer has sufficient properties to minimize particle displacement on a top surface of the at least one isolation layer. The at least one isolation layer has a greater acoustic impedance than that of the dielectric layer.
US08529983B2 Method and system for coating insertable medical devices
A coating system for coating an Insertable Medical Device (IMD) with one or more drugs is disclosed. The coating system includes a spray nozzle unit for coating the IMD with one or more drugs. The IMD includes a guiding member, a coating member and a supporting member. The IMD is passed through a protection tube such that the guiding member is located within the protection tube and an end of the supporting member is connected to a holder to expose the coating member of the IMD to the spray nozzle unit. The protection tube is received by a mandrel fixture which includes a circular disc for holding and rotating the protection tube and the IMD within the protection tube. When the protection tube along with the IMD is rotated, the spray nozzle unit coats the coating member of the IMD with the one or more drugs.
US08529980B2 Cereal flour composition containing wheat flour from sweet wheat and food product using the same
An object of the present invention is to provide a cereal flour raw material that can provide products having superb texture. A further object of the present invention is to provide a food product manufactured using such a cereal flour raw material. The present invention provides a cereal flour composition that contains wheat flour prepared from a type of wheat that does not express the three wheat starch synthase II proteins, and also does not express the three wheat granule bound starch synthase proteins, and another type of cereal flour; and a food product manufactured using such a cereal flour composition.
US08529977B2 Green tea beverage packed in container
Disclosed is a novel green tea beverage packed in a container which shows a good aroma release in the mouth and a lingering aftertaste, has a richness and concentration feeling in the flavor, and can be drunk delectably even in a cold state. Specifically disclosed is a green tea beverage packed in a container characterized in that: the concentration of saccharides, i.e., the sum of monosaccharides and disaccharides, is 150-500 ppm; the ratio by concentration of the disaccharides to the monosaccharides (disaccharides/monosaccharides) is 2.0-8.0; the ratio by concentration of electron-localized catechins to the aforesaid saccharides (electron-localized catechins/saccharides) is 1.8-4.0; and the ratio by content of furfural to geraniol (furfural/geraniol) is 0.5-3.0. It is preferred that the ratio by concentration of the aforesaid saccharides to soluble solid matters originating in tea leaves (saccharides/(soluble solid matters originating in tea leaves×100)) is 5.0 to 10.0.
US08529976B2 Protein composition and its use in restructured meat
The invention provides protein compositions containing structured protein products having protein fibers that are substantially aligned.
US08529975B2 Multi-functional base for a plastic, wide-mouth, blow-molded container
A container can have a body with an integrally formed base attached to the body. The base includes a concave annular wall extending from the container sidewall to a standing surface, and an inner wall extending from the standing surface to a substantially flat inner annular wall. The inner annular wall is recessed in the base and is substantially perpendicular to the container sidewall. The inner annular wall includes a centrally located dimple. The dimple includes a plurality of spaced apart and radially extending indented ribs. One or more of the ribs extend radially into a brace that tapers to meet the inner annular wall.
US08529974B2 Collapsible container
A collapsible container includes an outer cup, an inner cup located inside the outer cup, and a seal covering the container. The inner cup includes a base and a plurality of concentric sections that are configured to collapse toward an opening in the container, when a force is exerted toward the opening on the base. The plurality of concentric sections may include three concentric sections: a base section, a middle section, and a top section, wherein the base section perimeter is smaller than the middle section perimeter, and the middle section perimeter is smaller than the top section perimeter.
US08529970B2 High unsaponifiables and methods of using the same
Materials with high levels of unsaponifiable matter, such as extracts from plants, produce hydrolysates with unique properties. Properties that are sought in traditional saponification of natural oils are a result of low levels of unsaponifiables. These properties include high levels of aqueous surfactant activity, water-solubility or ready water-dispersability, activity as foaming agents, and the like. An objective of traditional saponification processes is to increase the water-solubility and surfactant activity of naturally occurring materials. It has been found that the application of a hydrolysis process to materials, particularly materials with a high level of unsaponifiables (e.g., at least 6 weight percent of the material), produces a product with properties significantly different from those products resulting from the conventional saponification of materials with less than 6 weight percent of unsaponifiables. The resulting hydrolysates from the practice of the present invention are substantive, resisting both physical and aqueous-based removal from skin and hair, exhibit a very unique surfactant property, and are not foaming agents with water. Hydrolysates according to the present invention may thus be used to enhance the performance of cosmetics and pharmaceuticals. These hydrolysates can be bioactive agents and alternative natural carrying agents for topical application of materials, particularly for application of materials to the skin or hair of subjects, and provide a substantive support for the materials carried.
US08529964B1 Method and composition for suppression and control of citrus canker and other plant diseases
Method and composition for treating citrus canker on citrus plants. The composition comprises copper nitrate complexed with amino acids from hydrolyzed yeast extract. In the method, an aqueous solution of this composition is sprayed on the plant foliage and absorbed by the plant.
US08529956B2 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.
US08529955B2 Methods of treatment using a gastric retained gabapentin dosage
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form.
US08529945B2 Oral antimicrobial pharmaceutical compositions
The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
US08529943B2 Angiopoietin derived peptides
Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
US08529942B2 Wound care dressing
A wound care dressing comprising one or more nonwoven blankets, where each nonwoven blanket comprises a plurality of fibers, where each of the plurality of fibers are formed from one or more saccharides in optional combination with one or more medicaments.
US08529939B2 Mucoadhesive drug delivery devices and methods of making and using thereof
The present invention relates to mucoadhesive drug delivery devices and their methods of preparation and use. More specifically the present invention relates to mucoadhesive drug delivery devices comprising one or more biocompatible purified proteins combined with one or more biocompatible solvents and one or more mucoadhesive agents. The mucoadhesive drug delivery devices may also include one or more pharmacologically active agents. The drug delivery devices of the present invention adhere to mucosal tissue, thereby providing a vehicle for delivery of the pharmacologically active agent(s) through such tissue.
US08529938B2 Combinations of viscoelastics for use during surgery
An improved viscoelastic composition useful in the performance of ophthalmic surgical procedures and especially cataract procedures is disclosed. The embodiments of the composition comprise combinations of sodium hyaluronate and chondroitin sulfate and exhibit an improved rheological profile.
US08529937B2 UHMWPE medical implant producing wear particles with benign body response
A substance, which contains anti-inflammatory substances, anti-microbial substances, anti-tumor substances, anti-viral substances, and/or bone stimulating substances, as an additive, can be added to an UHMWPE material for the production of a medical implant for imparting benign body response properties to the medical implant.
US08529936B2 Long term drug delivery devices with polyurethane based polymers and their manufacture
This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.
US08529935B2 Antibacterial hydrogel and use thereof in orthopedics
The present invention relates to hydrogels endowed with antibacterial properties, to be used for injection in damaged bones or in the production of antibacterial coatings of prostheses for implant in the human or animal body, obtained by loading with antibacterial agents hydrogels formed by derivatives of hyaluronic acid; the invention also relates to a kit of parts for producing the antibacterial hydrogels.
US08529933B2 Biphasic calcium phosphate cement for drug delivery
This invention relates to biomineral-based cements incorporating biopolymer carriers for the site specific introduction of natural or synthetic compounds that influence bone repair and/or patient recovery. The invention further relates to methods for producing such biphasic calcium phosphate cements for drug delivery.
US08529930B2 Polymers of fluorinated monomers and hydrocarbon monomers
It is provided a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer.
US08529925B2 Multi-active microtargeted anti-aging skin care cream polymer technology
A comprehensive, single agent cosmetic cream or lotion containing a high number of ingredients that target anti-aging in a defined manner. The cream or lotion contains a high number and variety of active substances that demonstrate excellent safety and efficacy in all of the various defined categories of skin aging, including but not limited to wrinkles, abnormal pigment or brown spots due to aging of the skin and an unexpectedly high efficacy in the reduction of redness and acne and rosacea blemishes.
US08529922B2 Polymer formulations for delivery of bioactive materials
PLGA, PLA and PGA polymers which have crystallinity resulting from the presence of long chain alkyl groups in terminal units. The polymers are particularly useful for drug delivery.
US08529921B2 Polyamide-5 compounds in cosmetic preparations
Polyamide-5 compounds show an increase of the care and/or efficacy properties of cosmetic or dermatological preparations, such as waterproofness, long-term stability, skin moisture and stickiness. The preparations preferably comprise one or more care agents or active ingredients selected from the group of UV filter substances, anti-wrinkle active ingredients, skin moisturizers and/or lipids.
US08529920B2 Low pH retinoid topical compositions
A low pH composition containing a retinol and a method for treating skin is disclosed. The composition contains (a) a retinoid and (b) an active acid, like an alpha-hydroxy acid or a beta-hydroxy acid, and has a pH of less than 5.
US08529918B2 Water-in oil emulsion foundation comprising a polyol
The invention relates to a fluid foundation in the form of water-in-oil emulsion comprising an oil and an aqueous phase comprising a polyol, and optionally polymethyl methacrylate particles, the water+polyol/oil weight ratio being greater than or equal to 0.8. The foundation slides well on the skin and has a sensation of lightness when applied.
US08529916B2 High concentration baclofen preparations
Stable aqueous solutions comprising concentrations of baclofen in the range of greater than 2.0 mg/mL up to about 10 mg/mL are disclosed. These solutions can be used as pharmaceuticals for parenteral or oral administration. The invention also provides methods of preparing said stable aqueous baclofen solutions.
US08529912B2 Group B Streptococcus polypeptides, nucleic acids and therapeutic compositions and vaccines thereof
This invention provides an isolated nucleic acid encoding a polypeptide comprising amino acid sequences of a streptococcal matrix adhesion E (EmaE) polypeptide. Antibodies to the EmaE polypeptide and immunogenic fragments thereof are also provided. This invention provides pharmaceutical compositions, immunogenic compositions, vaccines, and diagnostic and therapeutic methods of use of the isolated polypeptide, antibodies thereto, and nucleic acids.
US08529911B2 Small Streptococcus pyogenes antigens and their use
The present invention relates to a peptide consisting of one antigen of Streptococcus pyogenes (S. pyogenes) of any of the SEQ ID NOS: 1 to 7 or a functional active variant thereof, optionally further consisting of additional amino acid residue(s); a nucleic acid coding for the same; a pharmaceutical composition, especially a vaccine, comprising said peptide or said nucleic acid; an antibody or functional active fragment thereof specifically binding to the antigen; a hybridoma cell line which produces said antibody; a method for producing said antibody; a pharmaceutical composition comprising said antibody; the use of said peptide or said nucleic acid for the manufacture of a medicament for the immunization or treatment of a subject; the use of said antibody or functional fragment thereof for the manufacture of a medicament for the treatment of an infection; a method of diagnosing a S. pyogenes infection; a method for identifying a ligand capable of binding to said peptide; and the use of said peptide for the isolation and/or purification and/or identification of an interaction partner of the peptide.
US08529905B2 Soluble inhibitors of vascular endothelial growth factor and use thereof
The present invention relates to cDNA encoding a soluble neuropilin protein (sNP) which is isolated from neuropilin (NP) producing cells or is recombinantly engineered from NP-encoding DNA. NP-1 and NP-2 are preferred NPs but any neuropilin or VEGF receptor (VEGFR), where the constituents share at least about 85% homology with either of the above VEGF165R/NP-1 and NP-2. More preferably, such constituent shares at least 90% homology. Still more preferably, each constituent shares at least 95% homology.
US08529901B2 Composition of a first non-labeled monoclonal antibody binding to a tumor antigen and a non-cross reactive second monoclonal antibody labeled with a NIR fluorescence label
This invention relates to a composition of a non-labeled monoclonal antibody binding to a tumor antigen and a second monoclonal antibody labeled with a NIR fluorescence label, binding to the same tumor antigen, wherein the first and second antibody exhibit no cross reactivity. The composition can be used for the treatment of patients suffering of solid tumors which are associated with an overexpression of such a tumor antigen. The invention further relates to a the co-administration of said first and second antibody as wells as to a method of acquiring a NIR fluorescence images of such tumors or the patients suffering from such tumors during the treatment of said patient with such composition.
US08529883B2 Dosage unit formulations of autologous dermal fibroblasts
Dosage units consist of an autologous cell therapy product composed of fibroblasts grown for each individual to be treated. The suspension of autologous fibroblasts, grown from a biopsy of each individual's own skin using current good manufacturing practices (CGMP), and standard tissue culture procedures, is supplied in vials containing cryopreserved fibroblasts or precursors thereof, having a purity of at least 98% fibroblasts and a viability of at least 85%, for administration of from one to six mL, preferably two mL, of cells at a concentration of from 1.0-2.0×107 cells/mL. When injected into the nasolabial fold wrinkles (creases on the sides of the nose that extend to the corners of the mouth), the autologous fibroblasts are thought to increase the synthesis of extracellular matrix components, including collagen, reducing the severity of these wrinkles. Dosage and timing of administration have been demonstrated to be critical to achieving clinically significant outcomes.
US08529882B2 Peptidomimetic protease inhibitors
The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel stereoselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.
US08529881B2 Peptides for active anti-cytokine immunization
Peptide of a size comprised between 5 and 40 amino acids, originating from a cytokine, in which at least one of its amino acids comprises at least one of its atoms separated by a distance d of less than 5 angströms from an atom of the receptor corresponding to said cytokine, the spacing d being evaluated on the basis of structural data, derivatives, immunogenic compounds comprising them, use of a peptide or peptide derivative or immunogenic compound for the preparation of a curative or preventative medicament intended for the treatment or prevention of diseases linked to an excess or to the presence of cytokines or for the treatment of an auto-immune disease and pharmaceutical compositions which contain at least one abovementioned peptide or peptide derivative or immunogenic compound as active ingredient.
US08529880B2 Biodegradable polyurethane/urea compositions
The present invention relates to biocompatible, biodegradable polyurethane/urea polymeric compositions that are capable of in-vivo curing with low heat generation to form materials suitable for use in scaffolds in tissue engineering applications such as bone and cartilage repair. The polymers are desirably flowable and injectable and can support living biological components to aid in the healing process. They may be cured ex-vivo for invasive surgical repair methods, or alternatively utilized for relatively non-invasive surgical repair methods such as by arthroscope. The invention also relates to prepolymers useful in the preparation of the polymeric compositions, and to methods of treatment of damaged tissue using the polymers of the invention.
US08529877B2 Benzylidene compounds comprising phosphono-groups
Disclosed is the use of benzylidene compounds comprising phosphono-groups for the protecting of human and animal hair and skin from UV radiation. The UV filters of the present invention represent oil-soluble substances which advantageously absorb in the UV-A and UV-B region.
US08529875B2 Tobacco alkaloid releasing chewing gum
The invention relates to a tobacco alkaloid releasing chewing gum comprising tobacco alkaloid, gum base, and chewing gum ingredients, said gum base comprising elastomer and resin-compounds constituting an amount in the range of about 2 to 20% by weight of said chewing gum.
US08529870B2 Crystalline molecular sieve EMM-7, its synthesis and use
The crystalline molecular sieve material EMM-7 has, in its as-synthesized form, an X-ray diffraction pattern including d-spacing maxima substantially as set forth in Table 1: TABLE 1 Interplanar d-Spacing (Å)Relative Intensity, I/Io × 100 8.40 ± 0.2w-m 6.80 ± 0.2w-s 4.46 ± 0.1m-s 3.73 ± 0.1m-s 3.68 ± 0.1m-s 3.40 ± 0.1s-vs wherein “vs” means very strong (greater than 60 to 100), “s” means strong (greater than 40 to 60), “m” means medium (greater than 20 to 40) and “w” means weak (0 to 20).
US08529869B2 Catalysts and method for the hydroamination of olefins
The present invention relates to a hydroamination catalyst comprising boron beta zeolites, wherein the hydroamination catalyst is doped with lithium, and also a process for producing it. The present patent application further relates to a process for preparing amines by reaction of ammonia or primary or secondary amines with olefins at elevated temperatures and pressures in the presence of the hydroamination catalyst of the invention.
US08529867B2 Aluminum-alkali hydroxide recyclable hydrogen generator
An aluminum-alkali hydroxide recyclable hydrogen generator is provided that enables generation of hydrogen for a consuming apparatus on demand. The hydrogen generator includes a source of aluminum, a source of a hydroxide, a source of water, and a reaction chamber, where the amount of at least one of the aluminum, sodium hydroxide, and water that is introduced into the reaction chamber is used to limit the chemical reaction to control the amount of hydrogen generated.
US08529865B2 Conversion of produced oxygenates to hydrogen or synthesis gas in a carbon-to-liquids process
Processes for making hydrogen and optionally carbon monoxide and their integrations in a Carbon-to-Liquids plant are disclosed. A first syngas produced by a first syngas generator is converted in a hydrocarbon synthesis process to hydrocarbon products, oxygenates and product water comprising dissolved oxygenates. The first syngas generator may use partial oxidation, reforming, gasifying, or pyrolysis of any solid, liquid or gaseous carbonaceous feedstock. The product water may be treated, for example by distillation and/or by stripping, to form an oxygenates-rich stream which comprises a reforming reactant and oxygenates originating from the product water. Oxygenates from the oxygenates-rich stream fed to a second syngas generator are converted under reforming conditions to form at least hydrogen. The hydrogen formed by reforming may be supplied to one or more units using hydrogen within a Carbon-to-Liquids plant.
US08529864B2 Process for hydrogen production
A process for hydrogen production at lower temperature by using Mn/ZnO, Cu/MnO, Cu/CeO2, CuCe/ZnO and/or CuMn/ZnO catalysts, wherein a partial oxidization of methanol (POM) process can be initiated at an ambient reactor temperature lower than 100° C. and then undertaken at a reaction temperature lower than 200° C., and wherein POM process not only generates hydrogen rich gas (HRG) containing 4% CO or less but also generates 1.8 moles hydrogen or more per 1 mole methanol consumed.
US08529860B2 Methods for producing silicon tetrafluoride
Methods for producing silicon tetrafluoride by acid digestion of fluoride salts of alkali metal or alkaline earth metal and aluminum, optionally, in the presence of a source of silicon; methods for producing silane that include acid digestion of by-products of silane production to produce silicon tetrafluoride.
US08529858B2 Energy efficient, low emissions shale oil recovery process
A process for the energy efficient, environmentally friendly recovery of liquid and gaseous products from solid or semi-solid hydrocarbon resources, in particular, oil shale or tar sands. The process involves non-oxidative pyrolysis to recover fluid energy values, oxidative combustion to recover energy values as recoverable heat, and environmental sequestration of gases produced.
US08529855B2 Methods and system for removing gas components from flue gas
A method for removing gas components SOx, NOx, and CO2 from a flue gas, comprises the steps of contacting the flue gas successively with first, second and third liquid mediums each of which provides a plasma containing reactive electrons or ions in an amount such that the gas molecules SOx, NOx, and CO2 are successively subjected to impingement of the electrons or ions in the respective plasma to enable the dissociation of the gas molecules SOx, NOx, and CO2 so as to remove SOx, NOx, and CO2 from the flue gas. A system for removing gas components SOx, NOx, and CO2 from a flue gas is also disclosed.
US08529851B2 Lithium aluminosilicate-based materials with negative thermal expansion coefficient in a broad temperature range preparation process and use
New process for obtaining lithium aluminosilicate-based (LAS) ceramic materials having a near-zero and negative thermal expansion coefficient within a temperature range of (−150° C. to 450° C.). These materials are applicable to the manufacture of components that require a high level of dimensional stability.
US08529847B2 Reagent kit for analyzing apparatus
A reagent kit is provided comprising a plurality of containers with top-side openings, a common support structure or a plurality of support structures associated to the containers, and a plurality of caps. Each container and cap is mountable or provided on the common or the associated support structure, wherein each cap is formed essentially rectangular, having two shorter edges and two longer edges, and comprises: a cap body, a lid hinged to the cap body so to pivot around a pivot axis at least between closed and opened positions, the pivot axis being essentially parallel to the shorter edges. The containers and associated caps are arranged in a row along a connecting line such that the pivot axes are orthogonal to the connecting line. For at least one of the containers, an end portion of the cap body opposite to the pivot axis is not covered by the lid.
US08529846B1 Composite health monitoring/damage mitigation using multi-component microcapsules
A system, method and apparatus in the detection of a scent to locate the damage and its extent and to aid in the repair manually or self-repair.
US08529842B2 Ceramic honeycomb body and method for producing the same
A honeycomb body includes ceramic walls all being entirely formed of printed layers forming channels through which a fluid can flow. The channels lie next to one another. At least one of at least one measuring sensor or electrically conductive mass forms a monolithic, unitary structure with one of the ceramic walls. Sensor material may be used as an alternative to ceramic material. A method of producing the honeycomb body is also provided.
US08529836B2 Apparatus for automated processing biological samples
The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.
US08529835B2 Biopolymer sensor and method of manufacturing the same
A method of manufacturing a biopolymer sensor including providing a biopolymer, processing the biopolymer to yield a biopolymer matrix solution, adding a biological material in the biopolymer matrix, providing a substrate, casting the matrix solution on the substrate, and drying the biopolymer matrix solution to form a solidified biopolymer sensor on the substrate. A biopolymer sensor is also provided that includes a solidified biopolymer film with an embedded biological material.
US08529834B2 Blood/air mass exchange apparatus
There is provided a mass exchange apparatus (114) for use in blood/air mass exchange comprising plural blood flow conduits for defining a blood flow from a blood flow inlet provided thereto; and plural air flow conduits for defining an air flow from an air flow inlet provided thereto. The plural air flow conduits and plural blood flow conduits at least partially comprise gas-permeable membrane material, and the conduits are arranged relative to each other such as to enable transfer of oxygen from the air flow to the blood flow and transfer of carbon dioxide from the blood flow to the air flow through the membrane material.
US08529829B2 High-strength hot-rolled steel sheet with excellent combined formability
Disclosed herein is a high-strength hot-rolled steel sheet which is characterized by high strength (in terms of tensile strength at 900 MPa level) and excellent combined formability expressed by balance between strength and ductility [tensile strength (TS)×total elongation (El)] and balance between strength and stretch flangeability [tensile strength (TS)×bore expanding ratio (λ)]. The hot-rolled steel sheet contains C: no less than 0.02% and no more than 0.15%, Si: no less than 0.2% and no more than 2.0%, Mn: no less than 0.5% and no more than 2.5%, Al: no less than 0.02% and no more than 0.15%, Cu: no less than 1.0% and no more than 3.0%, Ni: no less than 0.5% and no more than 3.0%, and Ti: no less than 0.03% and no more than 0.5%. (% means mass %) It also has a metallographic structure in longitudinal cross section such that the sum of bainitic ferrite and granular bainitic ferrite accounts for no less than 85% by area.
US08529824B2 Method for manufacturing pressure-resistant container liner and liquid crystal resin liner
A resin composition formed by mixing 99 to 70 weight % of specific whole aromatic polyesteramide liquid crystal resin (A) with 1 to 30 weight % of epoxy modified polyolefin-base resin (B) and by melting and kneading both of the resins, wherein the resin composition having a melt viscosity of 60 to 4000 Pa·s at a shear rate of 1000/second at a temperature which is 20° C. higher than the melting point and having a melt tension of 20 mN or more at a take-over speed of 14.8 m/minute, is melt within a temperature range of a melting point to the melting point +40° C., a parison (P) is formed by extruding it with an extrusion speed equal to or higher than 0.3 kg/minute and lower than 5 kg/minute, a pair of moldings placed so as to sandwich the parison (P) are closed at a predetermined mold closing pressure, and air is blown into the parison (P).
US08529820B1 Adjustable melt rotation positioning device and method
Methods and apparatus adjustably control the repositioning of non-homogeneous fluid conditions across the stream of a laminar flowing fluid to a desirable circumferential position. The invention is particularly applicable to controlling non-homogeneous melt conditions at about the intersection of two flow channels in systems having hot or cold flow channels. Various mechanisms are provided that enable simple adjustments of a flow diverter within a fluid rotation device, making either static or dynamic adjustments, so that the degree of fluid flow repositioning in a runner system can be changed without the need for mold disassembly or retooling. Various forms of actuators effect adjustment and may be manually manipulated or manipulated through various powered devices.
US08529818B2 Automated fiber placement in female mold
A method and system for forming a product including a layer of fiber to a surface of a mold is provided. The system includes a mold and an apparatus. The mold is configured to rotate about an axis of rotation. An apparatus includes a base and a head coupled to the base. The base is configured to rotate about the axis of rotation. The head is configured to apply the fiber to the surface of the mold to form the product. The product includes at least one layer including at least one fiber applied using centrifugal force.
US08529817B2 Stretched thermoplastic resin foam sheet and process for production of the same
The present invention provides a stretched thermoplastic resin foam sheet that has excellent flexibility even compressed to a thickness as thin as about 0.05 mm, and a method for producing the same. The stretched thermoplastic resin foam sheet of the present invention is producible by stretching a thermoplastic resin foam sheet and has a compressive strength of 1 to 500 kPa as measured in accordance with JIS K6767 when compressed in a thickness direction thereof to a thickness of 0.05 mm. Accordingly, the stretched thermoplastic resin foam sheet has excellent flexibility even compressed to a thickness as thin as about 0.05 mm and is suitably used as a sealing material for a small electronic device such as mobile phones.
US08529815B2 Polyolefin composition comprising crosslinkable polyolefin with silane groups, silanol condensation catalyst and silicon containing compound
The present invention relates to a composition comprising (i) a crosslinkable polyolefin with hydrolysable silane groups (A), (ii) a silanol condensation catalyst (B) of the formula Ar(SO3H)x as defined herein, and (iii) a silicon containing compound (C) selected from the group consisting of 3-ureidopropyltrimethoxysilane, N-trimethoxysilylmethyl-O-methylcarbamate, and mixtures thereof; to an article, in particular a wire or cable, comprising such a composition, and to the use of such a composition for producing the article. The present invention further relates to the use of silicon containing compound (C) as a processing aid in the compounding of polyolefin compositions and as a surface smoothening agent in polyolefin compositions. Finally, the present invention relates to the use of a silicon containing compound (C) as a drying agent for polyolefin compositions, as a corrosion inhibitor in polyolefin compositions comprising a Bronsted acid and as a pH controlling agent in polymer compositions comprising a Bronsted acid.
US08529812B2 Production of pearls based on expanded polymers
Pearls based on expanded polymers are produced by extruding an expandable composition containing a thermoplastic polymer and an expanding agent, and thereafter cooling and chopping the expanded material thus obtained.
US08529811B2 Component protective overmolding using protective external coatings
Techniques for component protective overmolding using protective external coatings include selectively applying a protective material substantially over one or more elements coupled to a framework configured to be worn, the elements including at least a sensor, and forming one or more moldings substantially over a subset or all of the framework, the protective material and the elements, after the protective material has been selectively applied, at least one of the one or more moldings having a protective property.
US08529810B2 Method of making a pattern on a building on site
The invention provides a method of making a pattern on a building on site, which comprises following steps: applying a base coat on a surface of said building; pressing and adhering a pattern mold onto said base coat before initial setting of said base coat so as to form a compound body of the base coat and the pattern mold; applying a cover coat on said compound body; releasing the mold so as to obtain said pattern. The decoration method of the invention makes the wall surface safe and solid, of a long service life, available of a variety of patterns and convenient to construct.
US08529802B2 Solution composition and method of forming thin film and method of manufacturing thin film transistor using the solution composition
Disclosed is a solution composition for forming a thin film transistor including a zinc-containing compound, an indium-containing compound, and a compound including at least one metal or metalloid selected from the group consisting of hafnium (Hf), magnesium (Mg), tantalum (Ta), cerium (Ce), lanthanum (La), silicon (Si), germanium (Ge), vanadium (V), niobium (Nb), and yttrium (Y). A method of forming a thin film by using the solution composition, and a method of manufacturing thin film transistor including the thin film are also disclosed.
US08529800B2 Oxides having high energy densities
Certain disclosed embodiments generally relate to oxide materials having relatively high energy and/or power densities. Various aspects of the embodiments are directed to oxide materials having a structure Bi(MjYk)O2, for example, a structure Lij(NijYk)O2 such as Li(Ni0.5Mn0.5)O2. In this structure, Y represents one or more atoms, each independently selected from the group consisting of alkaline earth metals, transition metals, Group 14 elements, Group 15, or Group 16 elements. In some embodiments, such an oxide material may have an O3 crystal structure, and/or a layered structure such that the oxide comprises a plurality of first, repeating atomic planes comprising Li, and a plurality of second, repeating atomic planes comprising Ni and/or Y.
US08529799B2 Manufacturing method of metal oxide semiconductor material for gas sensor
Provided is a manufacturing method of a metal oxide semiconductor material for gas sensors by which an oxide precursor and noble metal colloid particles will not readily cohere in the manufacturing process. The manufacturing process implements a precursor solution synthesis step 1 of synthesizing an oxide precursor solution in which an oxide precursor is dispersed, a pH adjustment step 3 of adjusting the pH of the oxide precursor solution, a precursor-colloid dispersion preparation step 5 of preparing an oxide precursor-noble metal colloid dispersion in which the oxide precursor and the noble metal colloid are dispersed substantially uniformly, a purifying step 7 of purifying the oxide precursor-noble metal colloid dispersion to obtain a purified oxide precursor noble metal colloid dispersion, and a freeze-drying step 11 of freeze-drying an precipitate of the purified oxide precursor-noble metal colloid dispersion.
US08529798B2 Process for improving the emission of electron field emitters
This invention provides a process for improving the field emission of an electron field emitter comprised of an acicular emitting substance such as acicular carbon, an acicular semiconductor, an acicular metal or a mixture thereof, comprising applying a force to the surface of the electron field emitter wherein the force results in the removal of a portion of the electron field emitter thereby forming a new surface of the electron field emitter.
US08529795B2 Wet-processible metal oxide solution, method of using the same, and organic photovoltaic cell of using the same
A method of preparing a wet-processible metal oxide solution and a method of fabricating a film using the same are provided. A metal oxide that has been widely used as a photocatalyst is improved and a metal oxide solution having new functionality is formed. The metal oxide solution is transparent, wet-processible, and facilitates electron transfer. The metal oxide solution can be applied in various ways to an electronic device and is well-suited for application to an electronic device using organic materials. Also, a titanium oxide solution functions to remove and block oxygen and moisture. Thus, when it is applied to an electronic device using organic materials that are vulnerable to oxygen and moisture, the lifetime of the device can be increased.
US08529794B2 Polymers comprising fused selenophene
The invention relates to polymers comprising fused selenophene rings, to their use as semiconductors or charge transport materials in optical, electrooptical or electronic devices, and to optical, electrooptical or electronic devices comprising them.
US08529789B2 Curable composition
A photochromic cured product exhibiting favorable photochromic properties such as a high color density and a large fading rate, and excellent base member properties such as a high hardness, a high heat resistance and a high impact resistance. A curable composition contains a polymerizable monomer which exhibits the L-scale Rockwell hardness of not larger than 40, a bifunctional polymerizable monomer which exhibits the L-scale Rockwell hardness of not smaller than 60, a polyfunctional polymerizable monomer which exhibits the L-scale Rockwell hardness of not smaller than 60, and a photochromic compound.
US08529783B2 Method for backside polymer reduction in dry-etch process
A method for preventing the formation of contaminating polymeric films on the backsides of semiconductor substrates includes providing an oxygen-impregnated focus ring and/or an oxygen-impregnated chuck that releases oxygen during etching operations. The method further provides delivering oxygen gas to the substrate by mixing oxygen in the cooling gas mixture, maintaining the focus ring at a temperature no greater than the substrate temperature during etching and cleaning the substrate using a two step plasma cleaning sequence that includes suspending the substrate above the chuck.
US08529781B2 Method for producing a component, in particular a micromechanical and/or microfluidic and/or microelectronic component, and component
A method for producing a component, and a component, in particular a micromechanical and/or microfluidic and/or microelectronic component, is provided, the component including at least one patterned material region, and in a first step the patterned material region is produced in that microparticles of a first material are embedded in a matrix of a second material, and in a second step the patterned material region is rendered porous by etching using a dry etching method or a gas-phase etching method.
US08529780B2 Ceramic substrate material, method for the production and use thereof, and antenna or antenna array
The invention relates to a ceramic substrate material having a first layer having a cavity structure formed therein, and at least one sealing layer situated on at least a part of the cavity structure. The first layer comprises at least one first component made of a crystalline ceramic material and/or a glass material as a matrix, the first layer containing a second component made of a further crystalline ceramic material, with selected mantle areas of the crystals and/or crystal agglomerates of the second component being etched out in such a way that the cavity structure is provided (preferably in the form of a pore and/or tube structure). The sealing layer seals the surface of the first layer in the areas on which it is situated (e.g., above the cavity structure), allowing application of thin-film structures to the cavity structure.
US08529776B2 High lateral to vertical ratio etch process for device manufacturing
A layer stack over a substrate is etched using a photoresist pattern deposited on the layer stack as a first mask. The photoresist pattern is in-situ cured using plasma. At least a portion of the photoresist pattern can be modified by curing. In one embodiment, silicon by-products are formed on the photoresist pattern from the plasma. In another embodiment, a carbon from the plasma is embedded into the photoresist pattern. In yet another embodiment, the plasma produces an ultraviolet light to cure the photoresist pattern. The cured photoresist pattern is slimmed. The layer stack is etched using the slimmed photoresist pattern as a second mask.
US08529774B2 Super-phobic surface structures
Superlyophobic Surface Structure, including a substrate having a surface; a plurality of nanoscale raised features on the substrate surface, each nanoscale raised feature having a length measured in a direction approximately perpendicular to the substrate surface, each nanoscale raised feature having a raised feature diameter along the length and measured in a direction approximately parallel to the substrate surface; a nanoscale top feature on each of a plurality of the nanoscale raised features, each nanoscale top feature having a top feature diameter measured in a direction approximately parallel to the substrate surface; in which an average top feature diameter is greater than an average raised feature diameter. Method of fabricating a Superlyophobic Surface Structure.
US08529773B2 Method for making micro-electro-mechanical system device
The present invention discloses a method for making a MEMS device, comprising: providing a zero-layer substrate; forming a MEMS device region on the substrate, wherein the MEMS device region is provided with a first sacrificial region to separate a suspension structure of the MEMS device from another part of the MEMS device; removing the first sacrificial region by etching; and micromachining the zero-layer substrate.
US08529772B2 Method and apparatus for fluid separation
A method and apparatus are disclosed for separating a multiphase fluid stream that includes a heavier fluid component and a lighter fluid component. The fluid flows along a first helical flowpath with a first pitch. The first helical flowpath is sufficiently long to establish a stabilized rotating fluid flow pattern for the stream. The uniform rotating fluid also flows along a second helical flowpath, the second helical flowpath having a second pitch greater than the first pitch. The lighter fluid is removed from a radially inner region of the second helical flowpath. The method and apparatus are particularly suitable for the separation of oil droplets from water, especially from water for reinjection into a subterranean formation as part of an oil and gas production operation. The method and apparatus are conveniently applied on a modular basis.
US08529768B2 Water softener system and method
A water treatment system is provided that includes first and second water treatment control valves. Each control valve includes orifices and a piston. Movement of the piston is operative to change the flow of water through the orifices. The inlet and outlet ports of the second control valve are reversed relative to locations of the inlet and outlet ports on the first control valve. Each control valve is in operative connection with a respective brine tank and a resin tank. A manifold is in operative connection with the inlet and outlet ports of the first and second control valves. The manifold includes an inlet and an outlet port and a three way valve. A controller is configured to selectively operate the three way valve to direct water from the inlet port of the manifold to one of the inlet ports of the first and second control valves.
US08529765B2 Ensiling biomass for biofuels production and multiple phase apparatus for hydrolyzation of ensiled biomass
A method, apparatus and system for the hydrolyzation of ensiled biomass is disclosed. Ensiled biomass is processed in multiple phases, resulting in a liquid precursor hydrozate and a solid precursor hydrozate. The liquid precursor having significant economic value, and being suitable for uses such as, for example, lower cost and improved efficiency ethanol production. A method for lower cost, improved efficiency alcohol production that uses the resulting liquid precursor hydrozate being produced at distributed sources is further disclosed.
US08529764B2 Solar powered aeration and microbial incubation system
Disclosed is a system and method for treating a body of water, without the necessity of being connected to an electrical grid, that includes photovoltaic collectors and a battery bank that is charged by the photovoltaic collectors. The photovoltaic collectors and the battery bank operate a series of air pumps that are connected to an air pump manifold to create a uniform source of compressed air that is distributed to a plurality of floating diffuser manifolds. A plurality of air stones are suspended under the floating diffuser manifolds that create air bubbles that are absorbed by the body of water and circulate said body of water to disburse a microbial fluid. In addition, an incubator system is also connected to an air pump that incubates microbes to form a microbial fluid that can be automatically dispersed throughout the body of water.
US08529763B2 Waste water treatment method
Systems and methods have been developed for reclaiming water contaminated with the expected range of contaminants typically associated with produced water, including water contaminated with slick water, methanol and boron. The system includes anaerobically digesting the contaminated water, followed by aerating the water to enhance biological digestion. After aeration, the water is separated using a flotation operation that effectively removes the spent friction reducing agents and allows the treated water to be reclaimed and reused as fracturing water, even though it retains levels of contaminants, including boron and methanol, that would prevent its discharge to the environment under existing standards. The treated water may further be treated by removing the methanol via biological digestion in a bioreactor, separating a majority of the contaminants from the water by reverse osmosis and removing the boron that passes through the reverse osmosis system with a boron-removing ion exchange resin.
US08529758B2 CO2-removal device and method
An electrolytic CO2-removal device for anion analysis of a liquid sample. The device includes a basic chamber and CO2-permeable tubing in the basic chamber. Anion exchange membranes are disposed on opposite sides of the basic chamber, and electrodes are disposed outside the membranes. The device can be integral with a suppressor in an ion chromatography system and/or an aqueous stream purifier. Also, methods performed by the device.
US08529755B1 Oil soluble additive injection apparatus
A lubricant additive dispensing apparatus comprising a base providing a manifold distribution to present lubricant to a series of dispensing chambers. The dispensing chambers are fabricated having a porous sidewall formed in a tubular shape. Additive is stored within a reservoir formed by the tubular shape. A delivery piston is provided proximate and in fluid communication with the manifold. The lubricant applies pressure to the delivery piston. The delivery piston applies pressure to the stored additive. The pressure forces a small volume of additive to pass through the porous sidewall, blending the additive with the flowing lubricant. The reservoir can be formed between an outer tubular member and an inner tubular member. Lubricant can pass through an interior of the inner tubular member, exiting a flow discharge port located proximate an end cap assembled to a distal end of the reservoir.
US08529748B2 Functional solution supply system
A sulfuric acid electrolyte is produced efficiently as a functional solution and persulfuric acid produced by electrolysis is supplied efficiently to a use side while suppressing self-decomposition thereof.A functional solution supply system adapted to electrolyze a sulfuric acid solution to prepare a functional solution and supply the functional solution to a use side, comprises a storage tank 2 for storing the sulfuric acid solution, an electrolyzing apparatus (electrolytic cell 3) for electrolyzing the sulfuric acid solution, heating means (heater 5) for heating the sulfuric acid solution, cooling means (cooler 4) for cooling the sulfuric acid solution, a first circulation line 11 for returning the sulfuric acid solution discharged from the storage tank 2 to the storage tank 2 through the electrolyzing apparatus without passing through the heating means, a second circulation line 12 for returning the sulfuric acid solution introduced from the use side (cleaning machine 1) to the use side through the cooling means and the storage tank 2 in this order without passing through the heating means, and a third circulation line 13 for returning the sulfuric acid solution introduced from the use side to the use side through the heating means (heater 5) without passing through the cooling means and the storage tank 2.
US08529745B2 Electrophoretic fabricated freestanding all-nanoparticle thin film materials
Methods and apparatus for electrophoretic fabricating freestanding all nanoparticle thin films, and the resulting compositions of matter, are described. A method includes electrophoretically depositing a thin film of nanoparticles on a sacrificial layer; and freeing the thin film from the sacrificial layer. A composition of matter includes a free standing thin film of nanoparticles with no functionalized nanoparticles or chemical cross linkers.
US08529736B2 System and method for metal cutting
According to various embodiment, a system includes an electrolytic cutting tool. The electrolytic cutting tool includes a first cathode configured to be positioned at a first gap away from a first side of a workpiece, a second cathode configured to be positioned at a second gap away from a second side of the workpiece. The first and second cathodes are positioned opposite from one another. The electrolytic cutting tool also includes a first electrolyte passage configured to flow a first electrolyte through the first gap between the first cathode and the workpiece, a second electrolyte passage configured to flow a second electrolyte through the second gap between the second cathode and the workpiece, and a power supply configured to flow current through the first gap and the second gap to cause electrolytic dissolution through the workpiece from both the first side and the second side.
US08529734B2 Wall protector for a heating wall head between two oven chamber openings of a coke oven battery
A coke-oven battery has at least two chambers separated by a heating wall head and having openings provided with vertical jambs juxtaposed with the head. An upright anchor post is spaced horizontally forward from the head, and a plurality of U-shaped yokes are provided between the post and the head. Biasers bear on the anchor post and press the yokes against the jambs and thereby press the jambs against the head. A thin-walled sheet-metal head cover having upright edges is clamped between the jambs and the head and extends horizontally as a single piece between the jambs.
US08529731B2 Process for fractionating sugarcane bagasse into high α-cellulose pulp, xylan and lignin
Sugarcane bagasse consists of mainly three polymeric components, namely cellulose (40-45%), hemicellulose (xylan) (28-30%), and lignin (19-21%). A process is herein disclosed for fractionating sugarcane bagasse into cellulose, hemicellulose and lignin with high purity α-cellulose, which is a useful raw material for preparing cellulose esters like cellulose triacetate and other high value-added cellulose plastics. Co-production and recovery of hemicellulose (xylan) and lignin in high yields and high purities, along with α-cellulose, is another important feature of this process. Sugarcane bagasse consists of a material known as pith which constitutes 30-35% by weight of bagasse. Pith contains cellulose, hemicellulose, and lignin, in addition to various other ingredients and cell mass. The process described herein discloses the use of partially depithed bagasse as a preferred raw material for fractionation. Use of sugarcane bagasse containing pith leads to a product which is lower in yield as well as poorer in color.
US08529723B2 Process of expediting activation of heat-expandable adhesives/coatings used in making packaging substrates
A method for manufacturing a multilayer sheet material includes, at some point during passage of the sheet material through a machine system, heating the multilayer sheet material with a microwave heater to expand a heat-expandable adhesive or coating applied to or within the multilayer sheet material. Various types of multilayer substrates may be created depending on the steps used and the application of the heat-expandable adhesive or coating. Additionally, a monolayer sheet may be coated with a pattern of heat-expandable coating before passage of the monolayer sheet through the machine system that heats the monolayer sheet to expand the heat-expandable coating applied to the monolayer sheet. The microwave heater used by the machine system may be a planar type and have a plurality of microwave guides surrounding a space through which the sheet material(s) pass. The microwave heater may be operable at multiple frequencies.
US08529720B2 Aerofoil sub-assembly, an aerofoil and a method of making an aerofoil
A method of making an aerofoil comprises the steps of providing first and second skin panels and first and second web-forming membranes. The web-forming membranes each have a series of elongate slots formed longitudinally therein so as to define a series of alternating wide and narrow strips. The wide strips of one membrane are arranged against the narrow strips of the other membrane and the skin panels are arranged either side of the two web-forming membranes. Parts of the web-forming membranes and parts of the skin panels are treated with a release layer and the sub-assembly is compressed and heated so as to effect diffusion bonding between those parts of the membranes and skin panels which are not treated with the release layer. The sub-assembly is then heated and inflated so as to draw the first and second skin panels apart and that, in turn, causes the web-forming membranes to form webs internally.
US08529719B2 Method of making medical tubing having variable characteristics using thermal winding
An efficient and cost-effective method of manufacturing a kink-resistant tube, wherein a coated wire is wound around a mandrel while simultaneously being heated to melt the coating, is provided.
US08529717B2 Structural mat for reinforcing a wind turbine blade structure, a wind turbine blade and a method for manufacturing a wind turbine blade
The invention relates to a structural mat for reinforcing a wind turbine blade structure. The structural mat comprises two or more groups of bonded fibers, the fibers being bonded by a matrix substantially preventing relative movement of said fibers and wherein said groups are connected to each other by connection means limiting the relative movement of said groups. The invention further relates to a wind turbine blade and a method for manufacturing a wind turbine blade.
US08529714B2 Roll mold, method for fabricating the same and method for fabricating thin film pattern using the same
The present invention provides a roll mold, a method for fabricating the same and a method for fabricating a thin film pattern using the same, to prevent dimensional variation of the mold and simplify the overall process. The method for fabricating a roll mold includes providing a rigid substrate or flexible substrate provided with a master pattern, providing a base roller arranged on the substrate provided with the master pattern, forming a mold surface layer on the substrate provided with the master pattern, forming an adhesive resin layer on the mold surface layer or the base roller, rolling the base roller over the rigid substrate or flexible substrate to form the adhesive resin layer and the mold surface layer on the base roller, and curing the adhesive resin layer and mold surface layer formed on the base roller to adhere the adhesive resin layer and the mold surface layer to the base roller and fix the same thereon.
US08529704B2 Vacuum processing apparatus and operating method for vacuum processing apparatus
An operation method for cleaning a vacuum processing apparatus includes feeding a cleaning gas into a film deposition chamber of the vacuum processing apparatus when a predetermined number of batches of film deposition process is finished. The predetermined number of batch of film deposition processes is calculated based on a film deposition-related operating time (a film deposition time and a film deposition preparation time) and a cleaning-related operating time (a cleaning procedure time, a cleaning procedure preparation time, and a pre-deposition film deposition time).
US08529701B2 Substrate processing apparatus
A substrate processing apparatus includes a reaction tube, the reaction tub including an inner tube made of quartz and an outer tube made of quartz; a manifold made of quartz disposed under the outer tube, a top surface of the manifold being in air-tight contact with a bottom surface of the outer tube via a sealing member; a seal cap cover made of quartz disposed under the manifold, a top surface of the seal cap cover being in air-tight contact with a bottom surface of the manifold via a sealing member; a seal cap covered by the seal cap cover, a top surface of the seal cap being in air-tight contact with a bottom surface of the seal cap cover via a sealing member; and at least one protrusion disposed at the bottom surface of one of the outer tube, the manifold, the seal cap cover, and combinations thereof.
US08529700B2 Apparatus for gaseous vapor deposition
A vapor deposition apparatus includes an insert within which a material is deposited on the surface of a film. A cassette includes end plates each having a rib that edgewise receive a spiral wrapping of a film at least 300 mm wide. Spaces between turns of the wrapping define a gas flow channel and spaces between adjacent turns of one rib define inlet openings that communicate with the channel. Each rib has a predetermined width dimension, a predetermined average thickness dimension, and a width-to-thickness aspect ratio of at least 2:1. The spacing between end plates is at least 300 mm and is also greater than the film width at deposition temperature. The width dimension of each rib is between about 0.5% to about 2.0% of the end plate spacing. A diverging flow director contacts one end plate to directing gaseous fluid toward the inlet openings in that end plate.
US08529699B2 Method of growing zinc-oxide-based semiconductor and method of manufacturing semiconductor light emitting device
A method includes the steps of, using water vapor and a metalorganic compound not containing oxygen, (a) performing crystal growth at a low growth temperature and at a low growth pressure in the range of 1 kPa to 30 kPa to form a low-temperature grown single-crystal layer; and (b) performing crystal growth at a high growth temperature and at a pressure higher than the low growth pressure to form a high-temperature grown single-crystal layer on the low-temperature grown single-crystal layer.
US08529698B2 Ingan columnar nano-heterostructures for solar cells
Methods, devices, and compositions of matter related to high efficiency InGaN-based photovoltaic devices. The disclosed synthesis of semiconductor heterostructures may be exploited to produce higher efficiency, longer lasting, photovoltaic cells.
US08529696B2 Method for producing hexagonal boron nitride single crystals
A method for producing hexagonal boron nitride single crystals including mixing boron nitride crystals with a solvent thereby obtaining a mixture, heating and melting the mixture under high-temperature and high-pressure thereby obtaining a melted mixture, and recrystallizing the melted mixture thereby producing hexagonal boron nitride single crystals, wherein the solvent is boronitride of alkaline earth metal, or boronitride of alkali metal and the boronitride of alkaline earth metal.
US08529694B2 Powdered acetylenic surfactants and compositions containing them
A composition including particles of a carrier having on a surface thereof a compound according to structure (A) wherein either m is 1 and R is according to structure (B) in which n is an integer from 3 to 7, or m is 2 and R is according to structure C in which p is an integer from 1 to 10. Such compositions are useful for a variety of applications, for example the preparation of mortars and cements.
US08529693B2 Adhesive strength enhancers for cementitious compositions
An adhesion bond strength enhancer for cementitious adhesive mortar is disclosed. The adhesion enhancer improves bond strength between the mortar and relatively hydrophobic plastic material, such as extruded polystyrene boards and expanded polystyrene boards of the type generally employed in Exterior Insulation Finishing Systems (“EIFS”). Preparation of non-caking, free-flowing, solid dialkyl sulfosuccinate compositions for use as the adhesion enhancer is also disclosed. The adhesion enhancer is attractive for large-scale application in mineral mortar dry-mixes or other solid construction materials. The invention can be used to improve the strength of an adhesive bond between a) gypsum based plaster or stucco and concrete or bricks, b) tile adhesives and concrete, and c) mineral mortars on polystyrene boards, among others.
US08529688B2 Phenolic compound and recording material
Provided is a recording material with a superior storage property for the background and image, particularly with a remarkable superiority in any of light resistance of the background, and light, moisture and heat resistance of the image. The recording material contains a phenolic compound represented by formula (I) [wherein R1-R3 each independently represent a hydrogen atom or C1-C4 alkyl group; R5 represents a hydrogen atom, C1-C4 alkyl group or C1-C4 alkoxy group, with the proviso that when R5 is a hydrogen atom, R4 is a C1-C4 alkyl group, when R5 is a C1-C4 alkyl group, R4 is a hydrogen atom, and when R5 is a C1-C4 alkoxy group, R4 is a C1-C4 alkoxy group].
US08529687B2 Oxidation of asphaltenes
A method for processing asphaltenes is disclosed. The method can include separating asphaltenes from an asphaltene-containing composition and oxidizing the separated asphaltenes to form oxidation products. Alternatively, the method can include oxidizing asphaltenes within an asphaltene-containing composition without first separating the asphaltenes. Once formed, the oxidation products can be combined with other hydrocarbons. The amount of oxidation can be limited to an amount sufficient to produce a mixture suitable for the desired application. This method can be used to upgrade asphaltenes from a variety of sources, including oil sands. The oxidation step can be performed, for example, by introducing an oxidizing agent and, in some cases, a catalyst into the asphaltenes. A solvent or miscibility agent also can be introduced to improve mixing between the oxidizing agent and the asphaltenes.
US08529684B2 Carrier solvent for fingerprint formulations
A method and composition for transforming a latent physiological biometric into a visible physiological biometric are provided, the method comprising: providing a latent biometric disposed on a surface of an article, wherein said biometric comprises at least one eccrine-derived compound; contacting said latent biometric with a developing solution, wherein said developing solution comprises at least one imaging reagent selected from ninhydrin and 1,8-diazafluoren-9-one and a carrier solvent comprising at least one C3-C4 hydrofluorocarbon; and reacting said imaging reagent with said eccrine-derived compound to produce a visible physiological biometric.
US08529682B2 Process for preparing an indicator composition and indicator compositions
Indicator inks, indicators formed by printing or otherwise utilizing the inks and host products utilizing the indicators are disclosed. Reactivity-enhancing adjuvants stimulate enhanced thermal reactivity of diacetylenic or other indicator agents capable of responding to ambient thermal conditions with a visual change signaling an end point. The diacetylenic or other agents may be sensitive or relatively insensitive to ambient temperatures. Use of a reactivity-enhancing adjuvant provides a useful means for adapting the reactivities of indicator agents to the response characteristics of prospective host products, for example perishables such as vaccines or fresh fish and maturables such as fruit, cheese and wine. Some exemplary adjuvants include low-temperature polymerization initiators, for example methyl ethyl ketone peroxide and polymerization accelerators, for example cobalt compounds. Such initiators and accelerators can also be used in combination.
US08529681B1 Biofouling-resistant ceragenin-modified materials and structures for water treatment
This invention relates to methods for chemically grafting and attaching ceragenin molecules to polymer substrates; methods for synthesizing ceragenin-containing copolymers; methods for making ceragenin-modified water treatment membranes and spacers; and methods of treating contaminated water using ceragenin-modified treatment membranes and spacers. Ceragenins are synthetically produced antimicrobial peptide mimics that display broad-spectrum bactericidal activity. Alkene-functionalized ceragenins (e.g., acrylamide-functionalized ceragenins) can be attached to polyamide reverse osmosis membranes using amine-linking, amide-linking, UV-grafting, or silane-coating methods. In addition, silane-functionalized ceragenins can be directly attached to polymer surfaces that have free hydroxyls.
US08529679B2 System and method for improving performance of an IGCC power plant
In certain embodiments, a system includes a gas cleaner. The gas cleaner includes a solvent to clean a syngas. The system also includes a heat exchanger configured to heat a liquid to generate a vapor. The system further includes a vapor absorption refrigeration (VAR) cycle coupled to the gas cleaner and the heat exchanger. The VAR cycle is configured to cool the solvent. In addition, the vapor drives the VAR cycle.
US08529678B2 CO2 recovery system and method
A CO2 recovery system includes an absorption tower and a regeneration tower. CO2 rich solution is produced in the absorption tower by absorbing CO2 from CO2-containing gas. The CO2 rich solution is conveyed to the regeneration tower where lean solution is produced from the rich solution by removing CO2. A regeneration heater heats lean solution that accumulates near a bottom portion of the regeneration tower with saturated steam thereby producing steam condensate from the saturated steam. A steam-condensate heat exchanger heats the rich solution conveyed from the absorption tower to the regeneration tower with the steam condensate.
US08529677B2 Carbon canister for vapor recovery systems
A carbon canister as utilized relative to underground fuel storage tank vapor recovery, including for the capture and purging of hydrocarbon vapors as air is introduced into and released from an underground storage tank, and wherein, in one form intended primarily for use in Stage II Vapor Recovery systems, the carbon canister includes a valve activated by weight of saturated carbon and wherein, in another form intended primarily for use in Stage I Vapor Recovery systems, the carbon canister is a free breathing carbon canister with a surge protection device.
US08529673B2 Safe gas sorbents with high sorption capacity on the basis of lithium alloys
A new lithium material with high surface area, a method of its production, and a process of using the given material in purification of hydrogen or inert gases stream from active impurities. The material is manufactured in a form of granules of 0.2-2.5 mm in diameter with the structure of a dendritic carcass and is characterized with high sorption capacity and resistance to chemical shocks.
US08529668B2 Deaerator outlet diffuser
A deaerator includes a case defining a vortex chamber and a fluid inlet for allowing a mixture of lubricating liquid and air to pass through the case into the vortex chamber. An air outlet allows air flow out of the deaerator, and a liquid outlet allows lubricating liquid flow out of the deaerator. A porous diffuser is positioned proximate the liquid outlet for slowing the flow of lubricating liquid.
US08529667B2 Method for the selective extraction of acids, bases and polar salts
A process for the extraction of an unwanted material from a gas or liquid comprising the steps of introducing an extraction liquid into the fluid having an unwanted liquid therein to form a physical microdispersion comprising a plurality of extraction liquid droplets and the fluid, allowing the plurality of extraction liquid droplets to interact with the unwanted component in the fluid, to cause the extraction liquid droplets to be “wetted out” and captured on a porous medium, where the liquid is further contacted by the gas and simultaneously formed into a plurality of coalesceable droplets, coalescing the coalesceable droplets into larger droplets containing the unwanted liquid, and separating the larger droplets containing the unwanted liquid from the fluid.
US08529665B2 Systems and methods for gas separation using high-speed induction motors with centrifugal compressors
Systems and processes are provided for gas separation using high-speed induction variable-speed motors to accelerate and decelerate centrifugal compressors suitable for use in pressure swing adsorption (PSA) or vacuum pressure swing adsorption (VPSA) processes.
US08529663B2 Process for removing a target gas from a mixture of gases by swing adsorption
The present invention relates the separation of a target gas from a mixture of gases through the use of engineered structured adsorbent contactors in pressure swing adsorption and thermal swing adsorption processes. Preferably, the contactors contain engineered and substantially parallel flow channels wherein 20 volume percent or less of the open pore volume of the contactor, excluding the flow channels, is in the mesopore and macropore range.
US08529657B2 Porous vent breather
A vent for an axle housing includes a first body portion and a second body portion. The first body portion has a plurality of pores defined therethrough. The first body portion defines a first cavity. The second body portion has a conical portion that extends between a throat and a neck portion that defines an opening. The second body portion defines a second cavity that fluidly connects with the first cavity. The vent permits air to pass from the axle housing, through the plurality of pores in the first body portion, through the first and second cavities, and out the opening of the neck portion while concurrently inhibiting egress of lubricant from the axle housing.
US08529650B2 Abrasive cleaning agent, method for manufacturing the same, and method for polishing using abrasive cleaning agent
An abrasive cleaning agent is provided which can be used for a polishing process for polishing a surface of a workpiece to form a mirror surface, which suppresses generation of static electricity and adhesion of stains to the workpiece, which decreases a crushing ratio, and which has a low environmental burden when the abrasive cleaning agent is disposed of. The above abrasive cleaning agent includes an elastic material containing a soluble nitrogen substance as a primary component, which is obtained from tubers of devil's tongue and which contains mannan as a primary component, and a 10% to 30% of water; and 1 to 30 percent by weight, with respect to the elastic material, of abrasive grains of size #220 or less, which are supported on surfaces of the elastic material and/or are buried therein, so that the grain diameter on the whole is in the range of 88 to 1,190 μm.
US08529647B2 Fuel reforming process for internal combustion engines
A fuel reforming system, process, and device including a catalytic chamber and a heating chamber. The catalytic chamber, further including a fluid fuel intake and a gaseous fluid exit port and at least one heat exchanger for distributing heat between the heating chamber and the catalytic chamber. The catalytic chamber further including a screen member having a surface, wherein the member includes a catalytic deposit made from a combination of platinum and rhodium alloy. A catalytic conversion of converting liquid fuel to gaseous fuel occurs within the catalytic chamber. Fuel exits the fuel reforming device through a gaseous fluid exit port. In the process of phase change from liquid to gaseous phase, there is no change of chemical composition and C8H18 remains stable throughout, except for an increase in Enthalpy (heat content) per mol.
US08529644B2 Method and apparatus to produce synthesis gas via flash pyrolysis and gasification in a molten liquid
Disclosed are a method and a corresponding apparatus for converting a biomass reactant into synthesis gas. The method includes the steps of (1) heating biomass in a first molten liquid bath at a first temperature, wherein the first temperature is at least about 100° C., but less than the decomposition temperature of the biomass, wherein gas comprising water is evaporated and air is pressed from the biomass, thereby yielding dried biomass with minimal air content. (2) Recapturing the moisture evaporated from the biomass in step 1 for use in the process gas. (3) Heating the dried biomass in a second molten liquid bath at a second temperature, wherein the second temperature is sufficiently high to cause flash pyrolysis of the dried biomass, thereby yielding product gases, tar, and char. (4) Inserting recaptured steam into the process gas, which may optionally include external natural gas or hydrogen gas or recycled syngas for mixing and reforming with tar and non-condensable gases. (5) Further reacting the product gases, tar, and char with the process gas within a third molten liquid bath at a third temperature which is equal to or greater than the second temperature within the second molten liquid bath, thereby yielding high quality and relatively clean synthesis gas after a relatively long residence time needed for char gasification. A portion of the synthesis gas so formed is combusted to heat the first, second, and third molten liquid baths, unless external natural or hydrogen gas is available for this use.
US08529642B2 Solid electrolytic capacitor and method for producing the same
An object of the present invention is to provide a solid electrolytic capacitor comprising an anode body composed of a sintered body, in which ESR scarcely increases even after reflow at the time of mounting when compared with that before mounting, and a method for producing the same. Disclosed is a solid electrolytic capacitor comprising an anode body composed of a sintered body, a dielectric layer formed on a surface of the anode body, a semiconductor layer formed on the dielectric layer, wherein the semiconductor layer comprises a layer of a conductive polymer containing a sulfur element and a conductor layer formed on the semiconductor layer, wherein the conductor layer comprises a layer containing silver, wherein the layer containing silver is less than 1.3 ppm by mass in the content of a sulfur element after heat history at 260° C. for 5 seconds.
US08529639B2 Liquid dye formulations in non-petroleum based solvent systems
A method of coloring a substrate is disclosed that includes the steps of dissolving a vegetable oil ester based solvent wherein the ester is selected from a group consisting of esters having carbon chain length of C-1 to C-18 in a liquid solvent dye to form a low-sulfur containing dye formulation such that the vegetable oil ester is present in an amount of between about 5 and 80 percent by weight of the dye formulation, and mixing sufficient amounts of the dye formulation with the substrate to produce mixtures of predetermined color in which the levels of toxic substrate are substantially less than in otherwise equivalent mixtures that include hydrocarbon-based solvents.
US08529638B2 Head hair dyeing composition
There is provided a head hair dyeing method using a two-part hair dye composition which contains a first part containing an alkali agent, a second part containing hydrogen peroxide and a non-aerosol type foamer container for discharging a mixture solution of the first part and the second part as foam, the composition containing a surfactant in at least one of the first part and the second part, the method including discharging the mixture solution as foam, applying the foam to the head hair, and then re-foamed on the head hair.
US08529637B2 Foam oxidative hair colorant composition with the free-base of 1,4-diamino-2-methoxymethyl benzene
An oxidative hair colorant composition to be dispensed from a manually-actuable, non-aerosol dispenser as a foam. The oxidative hair colorant composition contains the free-base of 1,4-diamino-2-methoxymethyl benzene to achieve for efficient dye precursor levels in formulation and to achieve a desire rheology profile of the oxidative hair colorant composition.
US08529631B2 Base component for a tibial implant
The invention relates to a base component for a tibial implant, comprising a lateral compartment (14), a medial compartment (12) and an anterior connection portion (16) which connects the lateral compartment (14) and the medial compartment (12) to one another at anterior. A portion (18) open to posterior is provided between the lateral compartment (14) and the medial compartment (12). The lateral component (14) and the medial component (12) each have a lower side and an upper side, with at least one of the lower sides being configured for the fastening of the base component to the tibia. A marginal web (22, 22′) is formed at at least one of the compartments (12, 14), starting from the upper side, said marginal web forming a receiving shell for a meniscus component (30, 32) of the tibial implant together with the upper side of the compartment. The height of the marginal web (22, 22′) in a posterior region is reduced with respect to other regions of the marginal web (22, 22′) at at least one of the two compartments (12, 14). The invention furthermore relates to a tibial implant and to a knee prosthesis.
US08529630B2 Patient selectable joint arthroplasty devices and surgical tools
Disclosed herein are tools for repairing articular surfaces repair materials and for repairing an articular surface. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.
US08529626B2 Systems and methods for stabilizing a functional spinal unit
Systems and methods for controlling motion and physiologic load sharing across a functional spinal unit defined by a pair of adjacent vertebrae and an intervertebral disc therebetween are provided. The systems may comprise a first component for repairing or replacing a disc nucleus, without substantially disrupting the annulus. A second component may be provided for attachment to the adjacent vertebrae, the second component being configured to control movement of the vertebrae relative to one another. The first and second components may be configured to cooperate simultaneously to control motion and collectively distribute physiologic load sharing across the functional spinal unit.
US08529618B2 Ostium support for treating vascular bifurcations
A prosthesis is disclosed for placement across an ostium opening from a main body lumen to a branch body lumen. The prosthesis comprises a radially expansible support at one end, a circumferentially extending link at the other end and at least one spiral frond extending axially therebetween.
US08529617B2 Stents including poly(L-lactide) formulations that minimize molecular weight drop during processing
A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
US08529615B2 Element that can be fixed in a blood vessel and is provided with biomarkers
An element is disclosed that can be fixed in a blood vessel of a living being has a base body to which a first substance and/or a second substance is/are applied at least in parts. In at least one embodiment, the first substance is determined in such a way that it can be detected from outside of the body of the living being by way of a first non-invasive detection method and reacts with at least one first biochemical substance that is released by the living being into the blood vessel during a first pathological condition of the living being, with the result that the quantity of first substance applied to the base body is reduced. The second substance is determined in such a way that it binds at least one second biochemical substance that is released by the living being into the blood vessel during a second pathological condition of the living being and the presence of the bound substance can be detected from outside of the body of the living being by way of a second non-invasive detection method.
US08529613B2 Adjustable thermal cap
A thermal cap that can fit a variety of head sizes is disclosed. The cap can include a shell having a fluid inlet and outlet, a sealing mechanism and removable sizing layers disposed within the shell. Depending upon the size of a patient's head, sizing layers can either be added to or removed from the outer shell to maintain a fluid circulation space between the head and the rigid shell and allow substantially even distribution of a thermal fluid about the scalp of the patient during operation. The shell is preferably rigid and an elastomeric member can seal the periphery of the cap to the patient's head to prevent leakage. Other types and aspects of thermal cap systems are also disclosed.
US08529609B2 Polyaxial facet fixation screw system
A screw system includes a screw and a washer assembly captive to the screw. The washer assembly is polyaxially pivotable relative to the screw. The screw may be freely rotated in one direction relative to the washer assembly, but frictionally binds with the washer assembly when rotated in a second direction.
US08529606B2 Surgical tether apparatus and methods of use
Methods and apparatus for controlling flexion in a spinal segment of a patient include performing a spinal fusion procedure on a pair of adjacent vertebrae in the spinal segment and implanting a constraint device into the patient. Adjusting length or tension in the constraint device allows the constraint device to provide a force a force resistant to flexion of the spinal segment undergoing fusion. The constraint device also modulates loads borne by the spinal segment undergoing fusion or tissue adjacent thereto.
US08529605B2 Variable angle connection assembly
In a preferred embodiment, the present invention provides a connection assembly that can be used to securely connect a spinal implant to a bone anchor. In particular, the present invention preferably provides a variable angle connection assembly that is able to securely connect the spinal implant to the anchors even when there is a variance in the angle and position of the anchors with respect to the spinal implant. Furthermore, in a preferred embodiment, the present invention provides a connection assembly that will not inadvertently lock the components of the connection assembly preventing the relative movement of the components.
US08529602B2 Self-contouring spinal rod
A self-contouring spinal rod assembly. The assembly has a proximal end, a distal end, and a length extending between the proximal end and the distal end. A plurality of rod elements extend along the length, such that each of the plurality of rod elements is in contact with an adjacent rod element. The plurality of rod elements are fixed against movement relative to each other at the distal end. The plurality of rod elements are movable relative to each other along a length proximal the distal end. A method of assembling the spinal rod assembly is also provided.
US08529599B2 Tissue tension detection system
An apparatus for indicating the amount of tension applied to separate internal organ sections includes a housing, a shaft extending from the housing, and a fastener applier. The fastener applier is supported on the shaft. The fastener applier includes an anvil assembly and a cartridge assembly. The anvil assembly is positionable between first and second positions relative to the cartridge assembly. The anvil assembly and the cartridge assembly include a tissue detection device positioned to contact separate internal organ sections to generate a signal indicative of an amount of tension between the organ sections as the anvil assembly moves between the first and second positions. The tissue detection device is operably coupled to a gauge configured and dimensioned to generate an output based upon the signal. The output indicates the amount of tension between the organ sections.
US08529597B2 Devices for reducing the size of an internal tissue opening
A medical system for treating an internal tissue opening can include a closure device and associated delivery device. The closure device can include a body portion operatively associated with a first anchor and a second anchor. The body portion can include a plurality of segments defining a multi-cellular structure. The closure device can be configured to apply lateral force to tissue of the internal tissue opening to bring tissue together. The closure device can have a substantially flat aspect, and have a depth thickness that is substantially greater than the thickness or width of a majority of the members forming the closure device to reduce out of plane bending. The closure device can also include a member adapted to induce tissue growth.
US08529592B2 Ultrasonic operating apparatus
An ultrasonic treatment instrument includes a piezoelectric element assembly, a probe, a backing plate, an electrode assembly, a cylinder and a cylindrical inner cover. The piezoelectric element assembly includes piezoelectric elements and generates ultrasonic vibration. The probe is connected to the piezoelectric element assembly and transmits the ultrasonic vibration. The backing plate is connected to the piezoelectric element assembly. The electrode assembly includes electrodes respectively clamped between the piezoelectric elements, electrifies the piezoelectric elements and generates the ultrasonic vibration. The cylinder is connected to the probe and locates the piezoelectric element assembly, the backing plate and the electrode assembly therein. The cylindrical inner cover includes an inner diameter larger than the backing plate and an outer diameter smaller than the cylinder. The inner cover is disposed between the backing plate and the electrode assembly, and the electrode assembly is disposed between the cylinder and the inner cover.
US08529590B2 Anastomosis device and related methods
Described are methods and devices relating to reconnecting the urethra and bladder after a radical prostatectomy, wherein the devices incorporate tissue approximating structure to maintain contact between a severed bladder neck tissue and a severed urethral stump tissue, preferably without the use of sutures.
US08529588B2 Multiple clip applier apparatus and method
A surgical clip applier includes a train of clips disposed in a plane with a single clip removed from the train of clips and disposed in a staging position. A pair of jaws are adapted to receive the single clip from the staging position by operation of a jaw loader moveable outside the plane of the train of clips. In an associate method, a handle assembly is provided which is moveable in an open stroke and a closed stroke. A source of surgical clips are provided along with a pair of jaws which are adapted to receive one of the clips as the handle assembly is moved in an open stroke, the jaws are open to receive the clip. Following the opening of the jaws, a jaw loader is extended to a position between the jaws to move the clip into the jaws. The handle assembly is moveable in a closed stroke during which the jaws are closed to crimp the clip. Prior to this closing of the jaws, the jaw loader is retracted from the position between the jaws leaving the clip in the jaws.
US08529583B1 Surgical clip removal apparatus
Apparatus and methods for removing surgical fasteners. The apparatus includes a mechanism for opening the fastener so that it may be removed from, for example, tissue, prostheses or graft material.
US08529580B1 Surgical grasping instrument with U-shaped jaws in combination with a tympanostomy tube
The surgical grasping instrument having U-shaped jaws has a pair of handles connected to a pair of U-shaped jaws by a pair of elongated arms. The lower jaw is rigidly connected to the anterior end of the lower elongated arm. The upper jaw is pivotally connected to the anterior ends of the upper and lower elongated arms. The upper and lower arms are held together in sliding contact so that sliding the upper arm pivots the upper jaw. Both handles have finger loops. The rearward handle is rigidly attached to the lower arm, and is pivotally attached to the forward handle. The forward handle is attached to the upper arm by a ball and socket joint so that pivoting the handles pivots the upper jaw. The U-shaped jaws are designed to grasp round or semi round objects, such as a tympanostomy tube.
US08529579B2 Apparatus, system, and method for intra-oral distraction
According to one representative embodiment, a method for distracting a segment of bone from a source bone includes providing a bone distractor that has a first end portion and a second end portion movable relative to each other. The method further includes coupling the first end portion to the segment of bone and coupling the second end portion to an anchor bone opposing the source bone. Additionally, the method includes actuating the bone distractor to move the first and second end portions closer to each other and pull the segment of bone toward the anchor bone. The method can also include fixing the source bone relative to the anchor bone. Further, the method can include positioning the bone distractor to the sides of the source bone, anchor bone, and a gingival layer covering the bones.
US08529576B2 Device, system and method for delivering a curable material into bone
A curable material delivery cannula device and method are disclosed. The device includes a cannula and a hub. The cannula includes an open proximal end, a deflectable segment forming a pre-set curve, a lumen, and side orifice(s) adjacent, and proximally spaced from, the distal end and fluidly connected to the lumen. When inserted within a guide cannula, the deflectable segment straightens. When distally extended from the guide cannula, the deflectable segment reverts to the curved shape, which may be used to create a void in the bone for receiving curable material. The distal end has a blunt tip for non-traumatic interface with bodily material. During use, curable material, such as bone cement, is delivered from the side orifice(s) in a radial direction relative to the lumen.
US08529574B2 Cutting guide for removal of cam lesion
A cutting guide for removing a lesion from a neck area of a femur has a body having first and second side rails. The first and second side rails are spaced in a direction perpendicular to the head neck axis of the femur when mounted adjacent a neck of the femur. A third rail has ends slidably mounted on the first and second side rails. The third rail can be resiliently deformable toward a surface of the neck of the femur. A carrier element slidably mounted on the third rail for movement therealong between the first rail and the second rail. A bone cutting tool such as a burr is mountable in the carrier element. The first and second rails are connected by a proximal rigid cross-member at first ends thereof adjacent a femoral head. The cross-member is shaped to conform to an outer surface of the femoral neck adjacent the femoral head. The second ends of the first and second rails are connected by a member having a mounting element thereon adjacent a trochanter area of the femur. The mounting element may be a bore for receiving a bone screw or bone pin.
US08529571B2 Jig and saw guides for use in osteotomies
An apparatus for locating a curvilinear cut in a bone comprises a jig body and a first arm, a top end of which is rotatably coupleable to a first portion of the jig body in combination with a second arm, a top end of which is rotatably coupleable to a second portion of the jig body separated from the first portion and a saw guide rotatably coupleable to the first arm, the saw guide including a bottom surface extending along a curve corresponding to a desired path through which a bone is to be cut, the saw guide including a locking feature receiving a bone fixation element which, in an operative configuration, is mounted in the bone to align the saw guide relative to the arm so that an operator may precisely align a desired axis of the saw guide with a longitudinal axis of the first arm.
US08529569B2 Method and apparatus for preparing a proximal femur
A system for preparing a proximal femur can include a broach that includes a broach body having an anterior side, a posterior side, a lateral side and a medial side. The medial side can have a roughened cutting surface. The lateral side can have a smooth, non-cutting surface. The system can further include a cutting scribe assembly and a cutting guide assembly.
US08529562B2 Systems and methods for endometrial ablation
Methods, systems and devices for endometrial ablation. In accordance with a method, a working end of an RF ablation device is positioned in a patient uterus to contact endometrial tissue, the working end comprising a dielectric wall capable of non-expanded and expanded shapes. An indicator mechanism is operatively coupled to the wall and configured to indicate non-expanded and expanded shapes of the wall. An expandable member, such as a balloon, is provided that expands to close the cervical canal during ablation.
US08529561B2 Lateral laser fiber for high average power and peak pulse energy
An improved optical fiber comprising a waveguide with an input for coupling focused laser energy into the waveguide and communicating electromagnetic radiation in a propagation direction to an internally reflective tip of the waveguide, a tissue contacting surface wherein the light path from the reflecting surface to the transmitting surface in substantially homogenous in refractive index and cooled by fluid flow. In minimizing the variations in refractive index within the lateral light path, while providing active cooling directly below the tissue contact surface, the invention prevents internal reflections and beam distortion and greatly improves the efficiency and durability of the laterally directing probe. Free rotation of the tissue contact surface, about the lateral tip, may be provided and tissue vaporization efficiency may be improved by providing a morcellating tool on the tissue contact surface.
US08529559B2 Methods and devices for refractive treatments of presbyopia
Presbyopia in a patient's eye is treated by inducing spherical aberration in the central section of the pupil, while the peripheral section of the pupil is treated in a manner other than the central section of the pupil. For example, the peripheral section of the pupil may remain untreated, or high-order aberration may be controlled, and/or a second area of spherical aberration may be provided with different focus power.
US08529558B2 High-order optical correction during corneal laser surgery
Systems and methods related to corneal ablation for treatment of one or more high-order optical aberrations are provided. A method includes providing a defect-correcting prescription, determining an ablation profile to impose the prescription on the cornea, and determining a sequence of laser-energy ablations to impose the ablation profile on the cornea. The prescription comprises a high-order optical correction. The ablation profile includes a first-segment profile and a second-segment profile. The second-segment profile corresponds to at least one high-order optical correction. The ablation sequence includes applying ablations corresponding to the first-segment profile prior to applying ablations corresponding to the second-segment profile.
US08529554B2 Treatment instrument operation unit and medical system with treatment instrument operation unit
A treatment instrument operation unit is provided with a drive unit, an operation portion installation section and a command signal output section. The drive unit drives an operation portion for operating each treatment section of the respective treatment instruments. The operation portion is attached to the operation portion installation section provided to the drive unit. The command signal output section outputs an installation start signal to a controller for notifying that the installation of the treatment instrument has begun upon installation of the operation portion in the operation portion installation section. After outputting the installation start signal from the command signal output section to the controller, the drive unit drives the operation portion installation section to the position where the operation portion is allowed to be installed based on the control signal outputted form the controller.
US08529550B2 Implant delivery catheter system and methods for its use
Catheter systems and methods for implanting helical or dart-like implants into the myocardium or other body tissue. The catheter system includes a helix for fixing the distal end of the catheter to the myocardium, an implant held by the helix, mechanisms for driving the fixation helix into the myocardium, and mechanisms for driving the implant into the myocardium, removing the fixation helix and leaving the implant behind. The implant may be coated, filled, or made of a drug or drug eluting compound, or drug delivery matrix of any composition.
US08529548B2 Wound treatment apparatus and method
An apparatus and method for aspirating, irrigating and/or cleansing wounds is provided. The apparatus and method include one or more of the following: simultaneous aspiration and irrigation of the wound, supplying of thermal energy to fluid circulated through the wound; supplying physiologically active agents to the wound; a biodegradable scaffold in contact with the wound bed; and application of stress or flow stress to the wound bed.
US08529543B2 Apparatuses and methods for medication administration
A method of delivering medication to a patient includes inserting a medication administration device into a rectum of the patient, inflating a balloon of the medication administration device to retain the medication administration device in the rectum, delivering a first dose of a medication through the medication administration device such that the first dose of medication is applied to a distal portion of the rectum, delivering a second dose of a medication through the medication administration device such that the second dose of medication is applied to the distal portion of the rectum, and leaving the medication administration device in the rectum until it is dislodged for defecation. The first and second doses are delivered without removing the medication administration device from the rectum between doses.
US08529535B2 Disposable wearing article
A disposable wearing article is provided with a pair of liquid-barrier sheets on a body-side surface of the article. A dimension by which distal edges of distal zones of the barrier sheets are spaced from each other in a transverse direction is gradually enlarged from a rear end toward a front end of the article. An end sheet functioning to pull the distal zones closer to each other in the transverse direction is attached to the distal zones extending toward the rear end so as to extend between the distal zones.
US08529530B2 Drainage pump unit
The drainage pump unit according to the invention for aspirating body fluids by means of a suction pump comprises a drainage pump device with a pump housing (4) for receiving the suction pump, and a fluid collection container (5) that can be secured releasably on the pump housing (4). The drainage pump unit also comprises a pump-side attachment part (2) which has a connection element for connection to a patient-side drainage tube (10). The attachment part (2) is held releasably on the pump housing (4). This drainage pump unit allows the fluid collection container to be replaced without removing the drainage tube and, therefore, without disturbing the patient.
US08529528B2 Reduced-pressure wound treatment systems and methods employing microstrain-inducing manifolds
Microstrain-inducing manifolds, systems, and methods are presented that involve microstrain-inducing manifolds that include a plurality of shaped projections for creating microstrain. The shaped projections may be tapered projections. A system may include a sealing member for placing over the tissue site, a microstrain-inducing manifold, and a reduced-pressure subsystem that delivers reduced pressure to the sealing member. The reduced pressure causes the shaped projections to create microstrain at the tissue site. Other methods, apparatuses, and systems are also presented.
US08529527B2 Controller for an extremity hyperbaric device
A controller is operable to selectively supply gas to, and evacuate gas from, regions of a hyperbaric wound treatment chamber. The controller operates to inflate a passage or rib of the device to provide that the device is made sufficiently rigid for inserting a limb therethrough, and inflate an inflatable cuff to create a seal against the limb. The controller also operates to evacuate ambient air trapped within the chamber, and optionally partially evacuate the passage or rib, after the seal is created by the inflatable cuff, and then introduce oxygen into the chamber, and optionally inflate the passage or rib. The cuff, when inflated and creating a seal against a limb, optionally is at least partially within the chamber, and the treatment gas is supplied to the chamber to maintain the seal of the cuff against the limb.
US08529521B2 Low-dosage syringe
Low-dosage syringes for use in administering small dosages of medicine are disclosed. An illustrative low-dosage syringe can include an elongate syringe barrel having an interior chamber adapted to receive a supply of fluid, a plunger member slidably disposed within the interior chamber, and a tip member defining an inner lumen in fluid communication with the interior chamber. The configuration of the syringe barrel, including the wall thickness of the barrel relative to the outer diameter and to the length of the barrel, may permit small dosages of medicine to be accurately administered while also allowing the user to easily manipulate the syringe barrel with their fingers.
US08529518B2 Drug delivery device with cap functions for needle assembly
Drug delivery system comprising a main portion with a cap as well as a needle assembly with a needle mounted in a hub and a needle cap releasably mountable on the hub to cover the needle. The cap comprises gripping means reversibly operatable between a first condition in which there is no gripping engagement between the mounted cap portion and the needle cap, this allowing the cap portion to be removed from the main portion without removing the needle cap from the hub, and a second condition in which the cap portion grippingly can engage the needle cap of a needle assembly, this allowing the needle cap to be removed from the hub together with the cap. The cap further comprises user actuation means for operating the gripping means between the two conditions.
US08529516B2 Syringe for injection through zone of body
A syringe which disperses medicate across a zone in the body during apparent conventional operation. The improved syringe includes a barrel, a plunger, and an operating cylinder. In operation, the needle of the syringe is inserted into the body at the distal portion of the portion of the body which is to receive the medicate. A single arm is attached to the barrel and passes through an operating cylinder with a thumb rest on its top. As a result, in operation, the user draws the single arm up to the thumb rest, thus causing the syringe to withdraw during injection and leaving a patch of medicate during operation.
US08529510B2 Injection device
The present invention relates to an injection device comprises a generally elongated tubular housing having opposite proximal and distal ends; a needle shield sleeve slidably and coaxially arranged inside the housing and protruding a distance outside the proximal end of the housing; a syringe carrier mechanism comprising a syringe carrier slidably and coaxially arranged to the needle shield sleeve, wherein said syringe carrier comprises a syringe having a medicament and a needle; a first activator member slidably and coaxially arranged to the housing and connected to said needle shield sleeve; an actuating member slidably and coaxially arranged to the first activator member; a drive mechanism slidably and coaxially arranged to the actuating member and to the syringe carrier mechanism, said drive mechanism being controlled by the actuating member; a second activator member slidably and coaxially arranged to the distal end of the housing and fixedly connected to the actuating member; wherein the first and the second activator members are coaxially movable relative each other from a non-activation position wherein the activator members are abutting to each other to an activation position wherein the activator members are co-acting independent of the sequence in which said activator members are activated; and wherein only in the activation position is the actuating member capable of releasing the drive mechanism to move said syringe carrier mechanism for penetrating the needle and to deliver said medicament though the needle.
US08529508B2 Fluid ejection device and medical device
A fluid ejection device includes: a pressure chamber; an actuator having a displacement plane that varies the volume of the pressure chamber; a delivery channel pipe communicating with the pressure chamber; a first reflection surface of pressure wave formed as part of a paraboloid of revolution that reflects a plane pressure wave by displacement of the actuator, the plane pressure wave propagating through the pressure chamber; and a second reflection surface of pressure wave formed as part of a paraboloid of revolution or an ellipsoid of revolution which is disposed so as to face the first reflection surface of pressure wave, wherein the first reflection surface of pressure wave and the second reflection surface of pressure wave have a common first focus, and a pressure wave reflected from the second reflection surface of pressure wave propagates through the delivery channel pipe and ejects fluid.
US08529506B2 Therapeutic delivery devices, systems, and methods for multiple sclerosis, deep vein thrombosis, and pulmonary embolism
Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Multiple Sclerosis, Deep Vein Thrombosis, and/or Pulmonary Embolism or symptoms associated with these maladies. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Multiple Sclerosis, Deep Vein Thrombosis, and/or Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's veins are provided.
US08529504B2 Articulated catheter
Methods and apparatuses for manipulating an elongated flexible shaft of a catheter provide ease and reliability of positioning electrodes against or near tissue. Dual-bend flexible distal tips may be used in combination with flat wires. In some embodiments, flat wires which are free to rotate upon initial bending of shaft segments are employed. In some embodiments, one or more transition segments are used to relocate the satellite lumen-to-main lumen transition of pull wires away from a change in shaft stiffness.
US08529500B2 Needle-less injector and method of fluid delivery
A needle-less injector device for delivering a dose of fluid intradermally, subcutaneously or intramuscularly to an animal or human. The device includes an inner housing having opposed ends. A syringe is disposed in one end of the inner housing. The syringe includes a nozzle for delivering a dose of fluid held within the syringe. A plunger is movably disposed within the syringe. A spring powered hammer is movably disposed within the inner housing. The hammer cooperates with the plunger to drive the dose of medicament from the nozzle. An injection delivery spring for powering the hammer is positioned and compressed between the other end of the inner housing and the spring powered hammer. An outer housing slideably supports the inner housing. A skin tensioning spring is mounted between the inner housing and the outer housing, the skin tensioning spring biasing the nozzle of the syringe against the animal or human. A trigger mechanism is disposed in the outer housing, the trigger mechanism cooperating with the spring powered hammer to release the injection delivery spring, wherein the size of the injection delivery spring and the length of the hammer dictate the amount of dose delivered and whether the dose is delivered intradermally, subcutaneously or intramuscularly to an animal or human.
US08529499B2 Disposable injector with at least one central traction rod
A disposable injector having a housing (10) in which are arranged at least one mechanical spring energy reservoir (50), at least one cylinder-piston unit (100) that can be filled at least in part with an active substance, at least one piston actuation plunger (60) and at least one trigger unit (80). The spring energy accumulator plunger (60) has at least one tension bar (61) with at least one support surface (63) at the upper end thereof. Locking elements (16) supported on the housing lie on the support surface(s) and are secured in the locking position by a triggering element (82) placed in a locking position (8). The triggering element has a release position (9) that causes the locking element (16) to be unlocked for release of the active substance.
US08529497B2 Apparatus and method for controlling fecal diverting device
A fecal diverting device includes an internal balloon formed at the inside of a tubular body part disposed at the front end of a connection tube, at least one external balloon formed at the outside of the tubular body part, and an enema liquid injection hole formed through the forefront of the tubular body part and the at least one external balloon and an enema liquid to be injected into an intestinal tract of a patient via an enema liquid injection hole through a control tube. A device controller connected to the control tube regulates the amounts of fillers filling the internal balloon and the at least one external balloon and controlling the injection of the enema liquid, supplied from an enema liquid supplying unit, into the intestinal tract.
US08529494B2 Methods and apparatus for treating glaucoma
An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.
US08529491B2 Detecting blood flow degradation
A method for detecting blood flow degradation in a dialysis system. The method includes measuring a flow rate of blood in a blood line, calculating a current impedance value based on the measured flow rate, and comparing the current impedance value to a baseline impedance value.
US08529488B2 Apparatus for making extracorporeal blood circulation available
An apparatus for providing an extracorporeal blood circuit control includes a base module having a control device and a patient module releasably connected to the base module and having blood-conducting components of the extracorporeal blood circuit. A pivot system is also provided at the base module and at the patient module to pivot the patient module relative to the base module about a horizontal axis.
US08529486B2 Citrate anticoagulation system for extracorporeal blood treatments
A hemofiltration system and method for pumping blood from a patient's blood stream into an access line, introducing an anticoagulant solution into the pumped blood, filtering the pumped blood and delivering it to a return line, introducing a substitution fluid into the pumped blood, introducing a calcium and magnesium solution into the blood traveling through the return line, and returning the blood back to the patient's blood stream.
US08529484B2 Orthotic foot brace
An orthotic foot brace for a person wearing a footwear includes: a lower leg holder; a lower leg strut extending downwardly towards the footwear; a foot strut having a rear section secured to the vertical strut, at least one of a median section and a lateral section located on a respective side of the footwear and extending outwardly thereof, and a front section securable to an instep section of the footwear; and a brace retaining member secured to the foot strut juxtaposed to the footwear, and extending from the median side of the footwear to the lateral side of the footwear, outwardly thereof, and restraining a rearwardly pivotal movement of the brace.
US08529477B2 Control and integration of sensory data
A sensory data integration system for integrating sensory data generated by a first sensory substitution device and sensory data generated by a second sensory substitution device. The system includes a processor configured to generate an orientation signal indicative of a difference between a subject's orientation and an acceptable orientation. The orientation signal is based on the sensory data generated by the first sensory substitution device and the sensory data generated by the second sensory substitution device.
US08529475B2 Device for analyzing gait
A method and device for analyzing a gait of a person includes a magnetometer for fastening to a tibial segment of the person, in order to generate a signal representative of at least one projection onto a sagittal plane of an ambient magnetic field in which the magnetometer is immersed and a signal processor to identify instants and/or phases that are characteristic of the gait of the person by identifying particular points in the signal generated by the magnetometer as a function of time.
US08529473B2 Neural translator
A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.
US08529470B2 Lancets for bodily fluid sampling supplied on a tape
A supply of lancets for a multi-use lancing device are carried by a tape and sequentially brought from a storage position to an activating position by advancing the tape around a bend. The lancets are non-circular in cross-section along their longitudinal lengths, and in their activating position they extend from the tape such that their sharp tips are available for lancing tissue. The carrying tape can be arranged in reel-to-reel format in a housing having a lancing opening. The lancets can be integral with the tape and activated to move the lancet through the lancing opening by moving the tape along its tape path or by translating a dedicated service loop of the tape. The lancets can also be independent from the tape and activated through the lancing opening by a separate lancing actuator. A test media can be included on the carrying tape and the housing can contain a sensor to yield an integrated lancing and testing device.
US08529469B2 Fecal examination method and collection container
A method for conducting a fecal examination includes providing a collection spoon and a collection container comprising a transparent body having a cap which can be removed to permit fecal matter to be received in the collection container with the spoon to be mixed with a flotation material to aid in separating the fecal matter and ova or eggs of parasites that may be contained in the fecal matter and then dispensed through a filter mounted in the cap of the collection container to a test tube and a cover slip on the test tube for examination of the filtered material for the presence of the ova of parasites.
US08529462B2 Apparatus and method for passive testing of alcohol and drug abuse
An automated system and method for passive testing of alcohol and drug abuse. The system enters a participant or subject into the system who is to be monitored during a probationary or other program for alcohol or drug abuse offenders. The system provides a drug testing home device or a drug testing kiosk device for use by the participant. The system enrolls the biometrics information of the participant into the computer system (e.g., finger print, voice, image, volatile compound organic gas level, and pH level). When the participant is to be tested in accordance with a testing schedule, the system validates these same biometrics of the participant, conducts the test, and then analyzes the test information for determining if the participant has been using alcohol or other drugs and should be subjected to a confirming urinalysis exam.
US08529456B2 Heart age assessment
An automated method of determining a measure of a subject's heart age comprising the steps of: prompting a user for a plurality of inputs, each relating to an attribute of the subject, each attribute defining one or more of a demographic status of the subject, a lifestyle status of the subject, a physical condition of the subject and a medical history of the subject; receiving, from the user, a plurality of said inputs; determining from said received inputs, a set of parameters for which input data has been received as input from the user; selecting a heart age calculation algorithm from a predetermined set of heart age calculation algorithms according to said set of parameters; and calculating a heart age for the subject according to the selected algorithm; and providing as output said calculated heart age.
US08529453B2 Respiratory-gated therapy assessment with ultrasonic contrast agents
An ultrasonic imaging apparatus and method are described for monitoring the progress of therapy for pathology such as lesions, tumors, and metastases by means of contrast agent imaging. A sequence of images are acquired as a bolus of contrast agent infuses the tissue containing the pathology. Time-intensity curves of pathology and normal tissue are produced and used to measure perfusion in the pathology as affected by therapy. The motional effects of respiration can be taken into account during image acquisition by detecting the position of a landmark such as the diaphragm in each of the images of the sequence and discarding from processing those images which exhibit a change in the position of the landmark relative to the probe.
US08529450B2 Device for performing a cutting-balloon intervention
The invention relates to a device for performing a cutting-balloon intervention that includes a cutting-balloon catheter with an expandable balloon having axially arranged knives, with the cutting-balloon catheter having a pre-mounted stent.
US08529449B2 Method and system of thermoacoustic computed tomography
The present invention is a directed to method and system of TCT imaging whereupon data associated with unmeasured or inadmissible transducer locations is determined from data acquired at measured or admissible transducer locations. The invention analyzes measured TCT data associated with several transducer locations to provide an estimate of unmeasured data so as to complete a full data set for image reconstruction. In this regard, by measuring TCT data at many points on the surface of a hemispherical bowl or sphere in which an imaging object is placed, mathematical coefficients may be determined for the TCT data as a function of transducer location. From these coefficients, the unmeasured transducer locations may be evaluated such that data associated with the unmeasured transducer locations may be estimated and utilized for image reconstruction to improve image quality as well as improve the diagnostic sensitivities or capabilities of the TCT system.
US08529443B2 Nasogastric tube for use during an ablation procedure
Embodiments of the present invention provide a nastogastric tube for deflecting an esophagus during an ablation procedure. According to one embodiment, the nasogastric tube includes a flexible tube comprising at least one lumen having proximal and distal ends, and an esophageal deflector positioned within the at least one lumen and configured to be mechanically actuated to assume a curved profile so as to deflect a portion of the tube between the proximal and distal ends. The esophageal deflector is configured to deflect the portion of the tube proximate to a retrocardiac portion of the esophagus such that the retrocardiac portion of the esophagus is deflected away from an ablation site.
US08529442B2 Channel laryngoscopes and systems
Video-based laryngoscopes having an external centrally located channel coursing from the handle to a curved blade configured to deliver an ETT to a trachea as visualized by a non-removable, or alternatively, a removable video camera and lighting unit located beneath the external channel. The channel laryngoscope may be made for single use in a patient and discarded, or be processed for re-use. Alternatively, the channel laryngoscope may have a removable video camera and lighting member located within an internal chamber that runs parallel with the external channel. In another embodiment a laryngoscope adapter may be detachably affixable to the channel laryngoscope equipped with the non-removable camera to provide a decontaminated or sterile surface to permit re-use of the channel laryngoscope without having to undergo washing or decontamination procedures.
US08529440B2 Endoscopy systems
An endoscope insertion assembly for performing endoscopy, including an endoscope insertion tube operative for passage through a body cavity, and an optical assembly operative for inspection of the body cavity, the optical assembly being selectably insertable within the endoscope insertion tube.
US08529439B2 Endoscopic system
An endoscopic system is composed by connecting an endoscope and peripheral equipment. The endoscope has an endoscope main body, and an imaging unit, which is slender imaging optics. The endoscope is constructed so that the endoscope main body and imaging unit are freely connectable and separable. The endoscope main body has an insertion part which is inserted into an abdominal cavity, a branch member, which is a middle end of the endoscope main body, and provided in a proximal end portion of the insertion part, a first extension part provided in the proximal end portion of the branch member, a main body operation unit provided in a proximal end portion of the first extension part, a universal cord, and a connection unit, which is provided in a proximal end portion of the universal cord, and is connected to the peripheral equipment.
US08529437B2 Multifunctional surgical instrument with flexible end effector tools
A surgical tool having proximal and distal ends and adapted to transverse a curved passageway comprises an end effector disposed on the distal end of the surgical tool, the end effector having a first body section and a second body section and a releasable connector joining the end effector first body section with the end effector second body section. The connector is operable to reversibly engage the first and second end effector body sections in a first fixed position and in a second movable position. The surgical tool further comprises an actuation device for moving the first and second end effector body sections from the first fixed position to the second movable position. The end effector is adapted to maneuver through a larger radius of curvature in the second movable position than in the first fixed position.
US08529432B1 Penile implant for aiding achievement of a penile erection
A device configured for being implanted in a male patient's body for assisting the patient to achieve an erection. The device includes at least two rods and an interconnecting structure. The rods can be selectively deployed to the penis shaft when an erection is to be achieved and retracted away from the penis shaft when the patient does not need to achieve an erection. The interconnecting structure is joined to the rods and is configured to stabilize the rods while the rods are in the penis shaft.
US08529431B2 Bariatric device and method
A bariatric device and method of causing weight loss in a recipient includes providing a bariatric device having an esophageal member, a cardiac member and a connector connected with the esophageal member and the cardiac member. The esophageal member has an esophageal surface that is configured to generally conform to the shape and size of a portion of the esophagus. The cardiac member has a cardiac surface that is configured to generally conform to the shape and size of a portion of the cardiac portion of the stomach. The esophageal surface is positioned at the esophagus. The cardiac surface is positioned at the cardiac portion of the stomach. The bariatric device stimulates receptors in order to influence a neurohormonal mechanism in the recipient.
US08529427B2 Applicators and methods for intraoperative treatment of proliferative diseases of the breast
A device for administering brachytherapy to a patient includes a vessel that may be in the form of a hollow cylindrical cup, for fleshing into and substantially filling the open-ended cavity. The vessel has a closed outer end, which may be a removable cover, and a source guide penetrates the closed outer end so as to extend deep into the vessel, to receive a radiation source in the source guide. A manipulator can be connected to the radiation source, and also to the source guide, for allowing several different types of manipulation of the source orientation and position within the vessel during the brachytherapy procedure.
US08529422B2 Apparatus for manufacturing of packaging container with reclosable connection
An apparatus for manufacturing and converting a container includes a platform for slidably accommodating a sheet of packaging material, an actuation mechanism for feeding the sheet through the platform, and a gluing device for applying glue to a portion of the sheet. The apparatus further includes a magnet applicator assembly housing a plurality of magnets, a slug applicator assembly housing a plurality of slugs and a folding mechanism to align the sheet in a final glued form. The magnet applicator assembly applies magnets to the sheet at a pre-determined time, and the slug applicator assembly applies slugs to the sheet at a pre-determined time. The magnet and the slug are attached to the sheet by the glue applied by the gluing device. The magnet aligns with the slug forming a reclosable connection.
US08529412B2 Omni-directional exercise device
This disclosure describes, generally, an omni-directional exercise device. The device includes a platform base and resistance bands coupled to the platform base. The device further includes one or more enclosures coupled to the plurality of resistance bands. The one or more enclosures are positioned on top of the platform base at a home position. The one or more enclosures are configured to slide on top of the platform base in a 360-degree range of motion such that the plurality of resistance bands provide resistance at any point on the platform base and are configured to return to the home position.
US08529411B2 Foot and ankle exercise device
The present invention relates to a rocker boot for stretching or strengthening muscles. The rocker boot may include a base having a arcuate surface and a footrest attached to the base. The footrest may be adjustable to provide one or more different configurations.
US08529408B2 Weight-lifting exercise machine
A weight-lifting exercise machine enables an athlete to lift a mass from an initial resting position. After the athlete releases the mass, the machine cushions the fall of the mass, such that the mass returns to its resting position without assistance from the athlete. The movements of the athlete and the mass can be tracked, preferably by wireless accelerometers attached respectively to the athlete and the mass, and data on such movements can be stored and analyzed. The machine provides a monitor to enable the athlete to track the progress of the exercise, and to determine whether the exercise is being performed correctly.
US08529406B2 Multiple-ratio automatic transmission control method and system for ratio upshifts
A speed ratio shaft control for multiple ratio vehicle transmission has controlled release of an off-going transmission clutch and controlled engagement of an on-coming transmission clutch during a speed ratio upshift, at least one clutch being a friction torque establishing clutch. A controller, using shift-timing software strategy, actively manages in real time a clutch torque level for each clutch so that transient torque disturbances in a transmission torque output shaft are mitigated.
US08529405B2 Ratio shift control system and method for a multiple-ratio automatic transmission
A control system and method for controlling a multiple gear ratio automatic transmission in a powertrain for an automatic transmission having pressure activated friction torque elements to effect gear ratio upshifts. The friction torque elements are synchronously engaged and released during a torque phase of an upshift event as torque from a powertrain source is increased while allowing the off-going friction elements to slip, followed by an inertia phase during which torque from a powertrain source is modulated. A perceptible transmission output torque reduction during an upshift is avoided.
US08529402B2 Pump arrangement
A pump arrangement for fluid in an automotive transmission system includes, but is not limited to a first, low-pressure pump stage and a second, high-pressure pump stage, the first pump stage supplying low-pressure fluid to a lubrication/cooling system and to the inlet of second pump stage, which supplies high pressure fluid to a hydraulic control system. Fluid from both systems is returned via a reservoir and filter to the first pump stage.
US08529400B2 Method for coupling an internal combustion engine of a parallel-hybrid drive train
A method of coupling a combustion engine of a parallel-hybrid drive train via a clutch positioned between the engine and an electric machine with the clutch device initially disengaged, the engine rotational speed approximately at an engine idling rotational speed, and the machine rotational speed larger than the engine idling rotation speed. When a request is made for a drive torque value which is larger than a torque threshold, the engine rotational speed is brought to a rotational speed value above the machine rotational speed and the clutch is slipping engaged once the rotational speed value is reached, while the engine, when the drive train decelerates and a request is made to couple the engine, is brought into deceleration cancellation and the engine rotational speed is brought up to the machine rotational speed while engaging the clutch and dependent on a transfer ability of the clutch.
US08529399B2 Method for controlling a hybrid drive
A method for controlling a hybrid drive of a vehicle, which includes at least one internal combustion engine and at least one electric machine, having a first clutch situated between the electric machine and the drive train of the vehicle and a second clutch situated between the electric machine and the internal combustion engine. Performance parameters of the hybrid drive are controlled as a function of the driver's intent.
US08529398B2 Force limiting device for a motor vehicle
A load limiting mechanism for a motor vehicle, comprising at least two parts (1, 2, 10, 12, 16, 20, 21, 46, 22, 40) controlled relative to one another with a frequency controlled oscillating movement. The parts (1, 2, 10, 12, 16, 20, 21, 46, 22, 40) moving relative to one another comprise interlocking gears (3, 4, 13, 15, 24, 25, 26, 27) and the frequency controlled oscillating movement results thereby that at least one of the parts (1, 10, 21, 22) compared to the other part (2, 12, 16, 20, 40, 46) executes a wavelike oscillating feed motion, in which the gears (3, 4, 13, 15, 24, 25, 26, 27) alternately become engaged and disengaged thereby dissipating energy.
US08529397B2 Gear system for a wind turbine
A gear system (1) comprising a main bearing (3), a main gear (5) and two or more pinion shafts (6). The main bearing (3) directly supports a torque inputting means (2) and defines a rotational axis (4). The pinion shafts (6) are each arranged to mesh with the main gear (5) at an exterior surface (7) of the main gear (5) in such a manner that torque transmitted from the main gear (5) is split into a number of parallel torque paths corresponding to the number of pinion shafts (6). At least the main gear (5), and at least part of its meshes to the pinion shafts (6) are arranged within a perimeter defined by the main bearing (3). The gear system (1) is compact due to the arrangement of the main gear (5) and meshes to the pinion shafts (6). At the same time it is easy and cost effective to manufacture because the pinion shafts (6) mesh to the main gear (5) via the external surface (7).
US08529394B2 Multi-ratio transmission
A multi step transmission comprising four planetary gear sets, shafts, and shift elements, the sun gear of gearset (P1) couples shaft (4) which couples housing (G) via brake (04), the carrier of gearset (P1) couples shaft (3) which couples housing (G) via brake (03), and drive shaft (1) via clutch (13), and shaft (6) via clutch (36). Shaft (6) couples the ring gear of gearset (P2) and is operatively connected to the sun gear of gearset (P4). Shaft (1) couples the sun gear of gearset (P2) and the carrier of gearset (P3). Shaft (5) couples the ring gear of gearset (P1), the carrier of gearset (P2), and the sun gear of gearset (P3). The ring gear of gearset (P4) couples housing (G). Output shaft (2) detachably couples shaft (7), which couples the ring gear of gearset (P3), via clutch (27), and operatively couples the carrier of gearset (P4).
US08529393B2 Lockable or releasable wheel system with bidirectional input and one-way output
The lockable or releasable gear train with bidirectional input and one-way output relates to a transmission structure, wherein the rotary direction of the input shaft of the gear train with bidirectional input and one-way output is changed to make the direction of the output of the output shaft to be constant, which is characterized by releasing the lockable or releasable mechanism, the output shaft is moved reversely when reversely driven.
US08529392B1 Transmission with double-sun, annular gear, and outer gear coplanar gear set
A transmission includes a coplanar gear set with a first sun gear member rotatable about a first axis of rotation, a second sun gear member rotatable about the first axis of rotation, a carrier member, and an outer gear radially outward of and concentric with the first sun gear member. A first annular gear meshes with the first sun gear member, and the outer gear meshes with the first annular gear and with the second sun gear member. The first annular gear is rotatable about a second axis of rotation and the outer gear is rotatable about a third axis or rotation.
US08529391B2 Gear train for a wind turbine
A gear train includes at least one planetary gear stage and one gear train stage. One end of a sun shaft of the planetary gear stage is concentrically surrounded by a hollow shaft of the second gear train stage. The sun shaft of the planetary gear stage is co-rotationally coupled to the hollow shaft by a denture clutch. A lubricant feed ring is arranged at a front face of the hollow shaft facing toward the sun gear of the planetary gear stage and has a cone-shaped passage opening, which has an internal diameter which decreases in the direction of the sun gear of the planetary gear stage, and concentrically surrounds the sun shaft of the planetary gear stage. At least one lubricant feed nozzle is aligned with a circumferential gap between the lubricant feed ring and the sun shaft of the planetary gear stage.
US08529387B2 Pulley with asymmetric torque-sensitive clutching
A pulley assembly for use in an automobile accessory drive system includes a shaft engaging hub, a pulley member, a nut treaded onto the shaft engaging hub, and a brake member interposed between the pulley member and the nut. The shaft engaging hub is engaged with an accessory input shaft for rotation therewith. Frictional engagement between the pulley member, the brake member, and the nut transfers torque from the pulley member to the input shaft. The pulley member includes an inner coupling surface and a peripheral belt-engaging surface. The nut includes an outer coupling surface. The brake member includes a first coupling surface in frictional engagement the outer coupling surface of the nut and a second coupling surface in frictional engagement with the inner coupling surface of the pulley member. When torque is applied to the nut in a first direction the out coupling surface of the nut couples to the inner coupling surface of the brake member such that the hub and the nut rotate with the pulley member. The outer coupling surface of the nut and the inner coupling surface of the brake member decouple when torque applied to the nut is in a second direction opposite the first direction such that the hub rotates relative to the pulley member.
US08529381B2 Divot tools and methods of making divot tools
Embodiments of divot tools having ball markers and methods of making divot tools are generally described herein. Other embodiments may be described and claimed.
US08529375B2 Golf ball having increased moment of inertia
Generally disclosed is a golf ball having a core and a cover layer. The cover layer includes a coating material thereon that increases the golf ball's moment of inertia. The coating material is coated on the cover layer in a pattern corresponding to one of the dimple pattern and the pattern of land areas separating the dimples. The golf ball's moment of inertia is increased while utilizing only a small amount of the coating material as a result of the pattern of coating material, which locates the coating material at an outermost radial distance from the golf ball's center of rotation (i.e., the golf ball's center of gravity). The increased moment of inertia causes the golf ball to have a lower rate of spin when hit by a golf club, thereby displaying different play characteristics.
US08529369B2 Golf club head
An exemplary golf club head having an increased amount of discretionary mass may be realized by utilizing improved drop angles, an improved average crown height, and/or articulation points. The discretionary mass may be placed low and deep in the club head to improve the location of the center of gravity as well as the inertial properties. A preferred break length may also be utilized to further improve the depth of the center of gravity. In one example, the center of gravity may be positioned to substantially align the sweet spot with the face center of the club head.
US08529364B1 Golf training aid
The present invention is an apparatus and method enabling a controlled approach to making accurate puts in golfing. The apparatus uses laser aiming, measured stroking distances, and a surface analysis aid to benchmark a perfect put. The method enhances control by eliminating the back half of the swing while providing data points for reassessment of performance during practice training.
US08529363B1 Self-attaching golf putter aid
The self-attaching golf putter aid includes an upper grip joined at a pivot point with a bottom bracket such that the upper grip can rotate about a vertical axis with the bottom bracket. The bottom bracket is designed to attach onto the handle of a putter via an adjustable strap. The aid is used by grabbing the upper grip with a first hand while grabbing the bottom bracket and handle of the putter with a second hand, and wherein the end user holds the upper grip stationary while swinging the putter to form a true and smooth pendulum golf putting stroke that is ideal when putting.
US08529355B2 Storage medium storing information processing program, information processing apparatus and information processing method
A game apparatus includes a CPU, and the CPU controls a moving object within a virtual space on the basis of acceleration data and angular velocity data which are transmitted from a controller. For example, before the angular velocity data is above a predetermined magnitude, a position and an orientation of the moving object is controlled on the basis of the angular velocity data. When the angular velocity data is above the predetermined magnitude, an initial velocity of the moving object is decided on the basis of the acceleration data, and a moving direction (orientation) of the moving object is decided on the basis of the angular velocity data. Thereafter, the moving object moves within the virtual space according to a general physical behavior.
US08529349B2 Networked gaming system communication protocols and methods
A system, method and apparatus for a gaming system is provided. The gaming system includes a rewards server and a separate gaming or slot accounting server. The system may further include a separate player tracking server. The system further includes one or more game machines. The game machines may include a base game, rewards tracking module, and a game management module. Further details will be apparent from the description, drawings and claims.
US08529346B1 Allocating and managing software assets
Among other disclosed subject matter, a computer program product is tangibly embodied in a computer-readable storage medium and includes instructions that when executed by a processor perform a method for allocating assets. The method includes assigning each of multiple operation sectors defined by a software program to respective ones of multiple load groups, each load group grouping at least one operation sector for loading assets of the operation sector into memory. The method includes assigning all assets from the multiple operation sectors into respective ones of multiple clusters based on associations between the respective assets and the multiple operation sectors. The method includes generating and storing a memory layout that assigns one of multiple memory locations to each of the multiple clusters for at least one of the multiple load groups.
US08529345B2 Gaming system including a gaming table with mobile user input devices
One aspect is directed to a system whereby a live gaming table system is provided with one or more handheld user input devices which, for example, may allow multiple different players to simultaneously or concurrently provide wager input data and/or other data to the gaming table system. In at least one embodiment, the handheld user input devices may form part of a multi-player touch input interface system which is operable to identify or determine where, who, and what transactions are taking place at a multi-player gaming table and/or multi-player gaming system.
US08529344B2 Game control program, game device and game control method, management server, and data managing method
A designer terminal according to an embodiment of the present invention is a game device operated by a designer. The designer terminal includes a stage setting unit that generates design data on a virtual space, in which players play games, according to instructions from the designer, a stage distributing unit that distributes the generated design data to an external unit, a game action data acquiring unit that acquires game data recording game actions taken in the virtual space at player terminals that have acquired the design data, and a game action reproducing unit that displays, on the screen of the designer, the game actions taken in the virtual space at the player terminals, based on the acquired game data.
US08529342B2 Gaming system with dedicated player gaming devices
In a gaming system players are assigned individual gaming devices comprising electronic game boards. Players access their assigned gaming device via a gateway from a remote presentation device such as a player's computer. The gateway confirms the identity of each player so that a player may only access their assigned and dedicated gaming device. When linked, an assigned gaming device generates wagering game data for presentation upon the player's remote presentation device. A casino may provide a number of traditional gaming machines and a plurality of dedicated or assigned gaming devices which permit remote player play.
US08529336B2 Apparatus, systems, and methods for implementing enhanced gaming and prizing parameters in an electronic environment
Forms of interaction with an electronic system, such as for games of chance, games of skill, and combinations thereof are described herein. A system is provided for effecting defined game play and prizing structure parameters in an electronic entertainment environment. The system may include an input for receiving the parameters, a memory coupled to the input for storing the parameters, a processing system coupled to the storage for generating game play to effect the defined parameters, storage for recording information regarding particular game play events and an interface for at least presenting game play events to users of the electronic entertainment system. In one mode of operation, one or more mandated parameters are externally imposed, and variable parameters are selected such that the mandated parameters are met globally, and such that the user experience is optimized.
US08529324B2 Powered air cleaning system and method of making same
A powered air cleaning system (31) and a method of making the system are disclosed. The system comprises a flow path (22) extending through the system from an air inlet (4) to a clean air outlet (5). A motor-driven fan (24) located along the flow path draws particulate debris laden air into the inlet and rotates it about an axis (A-A) to form a rotating flow that stratifies the debris laden air with the heaviest particles in the outermost orbits of the rotating flow. An ejector port (8) is provided for ejecting particulate debris laden air from the stratified rotating flow in the system to the environment. An air filter (9) located within the rotating flow and across the flow path upstream of the outlet filters air from the innermost orbits of the stratified rotating flow. The system is formed of a plurality of components (2, 3) separately mountable in remote locations (32, 33) in a device to be supplied with clean air. The components are interconnected with an intermediate pipe assembly (34).
US08529318B2 Sharpener
A sharpening device operable to maintain a stable angle of a cutting edge during sharpening is disclosed. A sharpening member reciprocates parallel to a first direction. The sharpening member comprises a sharpening surface comprising at least one groove along the first direction. Reciprocation can reduce a presence of a sharpening residue on the sharpening surface while maintaining a stable sharpening angle of a cutting edge.
US08529311B2 Magnetic and electronic toy construction systems and elements
Magnetic and electronic toy construction systems and elements are provided that include an assembly of at least two panels that have at least three magnets located around the perimeter of the panel such that the dipole axes of magnets in a single panel are coplanar and intersect to define a polygon. When attaching two adjacent panels, at least two ferromagnetic spheres are used such that the dipole axes of one magnet from each of the adjacent panels are collinear, and such that the dipole axes are collinear with the centers of the ferromagnetic spheres. In this manner, several panels configured in this way may be nested together to form great varieties of constructions.
US08529309B2 Backlit displays including organic light-emissive material
A display device comprising: a light switching unit comprising an array of pixels each operable to vary the transmission of light therethrough; and a backlight comprising a first series of regions of organic light-emissive material having a first emission color and a second series of regions of organic light-emissive material having a second emission color, each region of organic material being located so as to lie behind a plurality of pixels of the array in the viewing direction for backlighting those pixels; and at least one of the regions of organic light-emissive material being formed by a process of ink-jet deposition.
US08529306B2 Device for pedal powering a watercraft
The present invention is a device affording foot-powered propulsion of a watercraft by an occupant. The device consists of two levers, each with a shaft, serving as a fulcrum. When mounted on a host craft the force arms extend above the deck or floor of the vessel and each has a pedal attached to their end. The resistance arms extend beneath the hull of the craft and each has a folding paddle attached. The levers are linked so that pushing one pedal away from the operator forces the other pedal towards the operator. A back-and-forth pedaling motion moves the folding paddle blades, propelling the vessel. Direction of propulsion can be reversed by rotating the paddles 180 degrees. The invention is intended to be mounted to a watercraft, such as, a kayak that has been specifically designed for or altered to accept the device.
US08529305B2 Electric outboard drive
An electric outboard drive adapted to be mounted on a transom of a boat through a mounting bracket includes a driving device and a propelling device. Through engagement of a first transmission shaft with a second transmission shaft, the power of an electric motor of the driving device is transmitted to a propeller of the propelling device. As a result, when the electric motor drives the first transmission shaft to rotate, the propeller is rotated by the transmission of the second transmission shaft to propel the boat.
US08529302B2 Electrical connector for flat conductor
A connector comprising a connector main body for insertion of an object to be connected; a plurality of contacts disposed at intervals from one another within the connector main body in the width direction; and a freely rotatable press member for pressing respective contacts against the inserted object to be connected. When the press member is rotated in one direction, respective contacts are pressed toward the object to be connected by the press member and, when the press member is rotated in the other direction, the press of the respective contacts by the press member is cancelled. A rotation fulcrum of the press member is provided between one and the other ends so that when one end of the press member is pressed, the press member rotates in one direction and, when the other end of the press member is pressed, the press member rotates in the other direction.
US08529301B2 Shielded connector assembly
A connector assembly according to embodiments of the present disclosure is advantageously configured to allow a sensor connector to straightforwardly and efficiently join with and detach from a patient cable connector. Further, embodiments of the connector assembly advantageously reduce un-shielded area in an electrical connection between a patient cable and a sensor connector. In addition, embodiments of the connector assembly advantageously increase the shielding of detector signals coming from the patient sensor to the monitor.
US08529295B2 Surface mount multi-connector and electronic apparatus having the same
A surface mount multi-connector having movable contact sections with high contact reliability and providing connection portions with high coplanarity. The surface mount multi-connector includes a first body in which a plurality of first contacts having movable contact sections and end sections that extend oppositely to each other are held by insert molding, a second body in which a plurality of second contacts having movable contact sections and end sections that extend oppositely to each other are held by insert molding, and a third body that incorporates the first body with which the second body has been coupled so that the movable contact sections of the second contacts and the movable contacts section of the first contacts face in the same direction. Tips ahead of the movable contact sections of the first and second contacts elastically mate with catching parts formed on the inner wall of the third body, and connection portions of the end sections of the first contacts and connection portions of the end sections of the second contacts lie in a same plane.
US08529290B2 Connector apparatus having a detachable module
A connector apparatus having a detachable module includes a connector base and a detachable module. The connector base has an insulating body and a plurality of press-contacting terminals. A plurality of grooves are inwardly formed on a rear surface of the insulating body. The press-contacting terminals are correspondingly located in the grooves. A press-contacting portion of each of the press-contacting terminals extends along the upper surface of the insulating body and protrudes out from the upper surface. The detachable module is composed of a circuit board, an integrated circuit electrically connecting to the circuit board and a plurality of connecting pins arranged on the circuit board. When the detachable module is connected to the connector base, the connecting pins are electrically connected to the press-contacting portions, and the mainboard of a computer connected to the connector base can execute the function of the integrated circuit in the detachable module.
US08529289B2 Reconfigurable plug strip
A power strip for conducting electrical power between an electrical power outlet having at least a live receptacle and a neutral receptacle, and at least two electrical device power plugs, each plug having at least a live prong and a neutral prong. The power strip includes a first housing segment having a first receptacle configured to receive at least an electrically conductive portion of a first device plug and a second housing segment having a second receptacle configured to receive at least an electrically conductive portion of a second device plug. The second housing is coupled to the first housing for pivotal movement relative to said first housing.
US08529288B2 Cover for cable connectors
A cover and a system of covers/boots for placement in sealed relation over a connector or pair of connectors that is or are adapted to terminate a cable or splice together a pair of cables, preferably cables that carry signals received by a receiving apparatus on a cell tower. The covers include a cable end that sealingly receives a cable therein, an elongated body that provides secure cover to a cable connector, and an end that abuts a bulkhead or sealingly engages with a second cover when used in a splicing application.
US08529286B2 Detachment and displacement protection structure for insertion of flexible circuit flat cable
Disclosed is a detachment and displacement protection structure for insertion of flexible circuit flat cable. An inserter positioning section is formed on a flexible circuit flat cable and coupled with an inserter, which includes a metal member and a plastic member. In assembling, the plastic member is first positioned on a first surface of the inserter positioning section of the flexible circuit flat cable, and then the metal member is fit over the plastic member. A detachment and displacement protection structure is provided on the inserter positioning section to constrain the inserter from displacing and detaching in a flat cable extension direction due to being acted upon by an external force when the inserter is positioned on the inserter positioning section.
US08529285B1 Cable retention clip for rugged applications
A system and method for retaining a commercial off the shelf connector and cable into a connector on a pc is shown and described as having a wire bail or retaining clip, which is either screwed to or forced into a friction fit behind a rear panel of the PC at the COTS connectors. The bail or retention clip extends beyond the end of the connector and cradles the cord, this helps to distribute the weight of the cord/cable. Also, the clip is sized and configured to make inadvertent disconnection of the connector less likely.
US08529281B2 Connector
The invention provides a connector including first and second beams, first and second conductive plates, and an urging device. The first and second beams extend substantially in parallel with each other and include first and second accommodating recesses, respectively. The first and second recesses are opposed to each other and open toward distal end sides of the first and second beams. The first and second conductive plates are to be accommodated in the first and second accommodating recesses, respectively, and removably insertable from the distal end sides into the first and second accommodating recesses, respectively. The urging device urges the first and second conductive plates in directions close to each other.
US08529280B2 Electrical engagement apparatus, system and method
A device for securing a first electrical connector to a second electrical connector, comprising a bracket body; and at least one engaging portion extending from the bracket body to the second electrical connector and coupling to a portion of the second electrical connector. Also provided is a method of securing one electrical connector to another electrical connector and an interconnect system comprising a first connector, a second connector, a third connector, and an engaging device.
US08529278B2 Waterproof electrical connector and waterproof electrical connector assembly method
The invention is directed to a waterproof electrical connector that can prevent detachment of connector parts and enhance waterproofness. The connector includes a main housing, a cover housing, a contact, and a body. The main housing includes a mating protrusion, a fitting section, and a head portion. The contact includes a contacting portion that is received in the fitting section and an electric wire connection portion that connects to one end of an electric wire. The body covers at least a boundary portion between the main housing and the cover housing. The main housing further includes an outer circumferential wall positioned on an outer circumferential side of the boundary portion between the main housing and the cover housing.
US08529276B2 Connector to flex assembly
An electrical assembly combination comprises (a) a rigid assembly having a plurality of attachment element electrical contacts, (b) a flexible assembly having a plurality of flexible assembly electrical contacts, and (c) an intermediary device disposed between the rigid assembly and the flexible assembly. The intermediary device has connector electrical contacts including a first set exposed on a first base side and a second set exposed on a second base side. Each intermediary device electrical contact connects with an attachment element electrical contact or a flexible assembly electrical contact. Each attachment element electrical contacts is removably secured and electrically connected to the first set of intermediary device electrical contacts, and each of the flexible assembly electrical contacts is removably secured and electrically connected to the second set of intermediary device electrical contacts.
US08529275B2 Assembled component having electrical connector and electrical connector cap, electrical connector cap, and method of mounting electrical connector
An assembled component includes a plurality of electrical connectors to be disposed on a circuit board in a specific positional arrangement; and an electrical connector cap attached to the electrical connectors for joining the electrical connectors before the electrical connectors are disposed onto the circuit board. The electrical connector cap includes a main body extending in a first direction and a second direction perpendicular to the first direction on a plane parallel to the circuit board and a first fitting section including a first reference surface. Each of the electrical connector includes a second fitting section for engaging the first fitting section. The second fitting section includes a second reference surface for contacting with the first reference surface, so that the electrical connectors are arranged in the specific positional arrangement.
US08529273B2 Female terminal and charging connector
A female terminal (20) has a main portion (21). A contact-member accommodating portion (22) projects forward from the main portion (21) for accommodating a contact member (23) inside. The contact member (23) has circumferentially arranged contact pieces (23A) extending in a connecting direction with a male terminal (60). Intermediate parts of the contact pieces (23A) in an extending direction are curved radially inwardly, and the curved parts of the contact pieces (23) resiliently contact and hold the male terminal (60). The contact-member accommodating portion (22) has a front wall (22A) and a side wall (22B) between the front wall (22A) and the main portion (21). An entrance hole (22C) for the male terminal (60) is formed in the front wall (22A), and a first discharge hole (25A) for allowing the inside and outside of the contact-member accommodating portion (22) to communicate is formed in the side wall (22B).
US08529272B2 Rotary connector device
A steering roll connector includes a rotator, a sleeve, and a fixed casing. The rotator includes a claw and an inner cylindrical part, and is mounted to a steering shaft such that the rotator is rotated integrally with the steering shaft inserted in the inner cylindrical part. The sleeve includes a projection connectable with the claw, and is mounted to the rotator such that the sleeve is rotated integrally with the rotator. The fixed casing includes an outer cylindrical part, and is mounted such that the fixed casing does not follow rotation of the steering shaft inserted in the outer cylindrical part and such that the fixed casing is in contact with the sleeve. A combination of materials of the claw and the projection is such that occurrence of a squeak caused when the claw and the projection are rubbed against each other is suppressed.
US08529270B2 Interactive computer system for instructor-student teaching and assessment of preschool children
A computer system contains and displays a cartoon-like story with a plurality of displayed components (such as cartoon characters, play items, etc.) recognizable by a preschool student on a first portion of the display screen along with an accompanying voice message on the speaker. Written instructions for teachers to follow in a personal one-to-one interaction with one or more students are displayed on a second portion of the display screen. For some activities, the student may actually respond using the computer such as by touching a touch screen or using a mouse to select one of the displayed components in response to a request to select a displayed component having a predetermined aspect. For other activities the teacher enters the response of the student as observed by the teacher. When one or more correct responses are entered by the student or teacher, achievement of a goal can automatically be entered into the educational management system.
US08529268B2 Ski or snowboard teaching apparatus
In one example, an apparatus for teaching a student how to snow ski includes a removably attachable instructor component, a removably attachable student component, and means for temporarily securing the instructor component and student component together. The instructor component has a first end defining a cavity configured to receive a bottom end of an instructor's ski pole and a second end disposed opposite the first end. The student component has a first end configured to attach to a portion of a student's ski equipment and a second end disposed opposite the first end.
US08529266B1 Mathematical teaching apparatus and methods
A mathematical teaching apparatus includes a base ten platform formed with a planar array of ten receiving elements being substantially equal in size and arranged in a pattern, and ten counting tiles being substantially equal in size and shape. Each of the ten receiving elements is adapted to removably receive one of the ten counting tiles to arrange the ten counting tiles in the pattern of the ten receiving elements, and a base ten cover is adapted to be removably received upon the ten counting tiles received by the respective ten first receiving elements so as to cover the ten counting tiles.
US08529265B2 Method for teaching written language
A system and method for teaching combining letters, images and sounds. A keyboard having letters on keys has sounds associated with each key. Keys for words used in a lesson may be highlighted to provide clues how to spell a word. Sounds associated with a selected word may be played upon the successful completion of spelling of the word on the keyboard.
US08529256B2 Air water vacuum syringe and method of use
An air water vacuum dental instrument includes a handle; a head; an air control carried by at least one of the handle and the head; a water control carried by at least one of the handle and the head; a vacuum control carried by at least one of the handle and the head; and an air water vacuum tip coupled to the head and configured to provide at least air, water, and vacuum in a mouth of a dental patient at the air water vacuum tip.
US08529252B2 Reverse headgear with neck strap
The reverse headgear with neck strap has: a forehead-cap adapted to engage a patient's forehead; a chin-cap adapted to engage the patient's chin; and a frame interconnecting the forehead-cap and the chin-cap. The frame has side portions extending between the forehead-cap and the chin-cap defining rearward extending loops. A neck strap is releasably connected to the loops on opposite sides of the frame by hooks, the neck strap passing behind the patient's neck in order to apply a traction force to the chin cap to draw the mandible posteriorly. An M-shaped hook is attached to the chin-cap and extends in front of a mouth of the patient, the hook being configured to receive a tension applying elastic element attachable to the patient's upper teeth in order to apply anterior traction to the maxilla, thereby correcting a class III malocclusion by tensioning the maxilla forward and the mandible rearward.
US08529249B2 Flame holder system
A flame holder system includes a modified torch body and a ceramic flame holder. Catch pin(s) are coupled to and extend radially out from the torch body. The ceramic flame holder has groove(s) formed in its inner wall that correspond in number and positioning to the catch pin(s). Each groove starts at one end of the flame holder and can be shaped to define at least two 90°turns. Each groove is sized to receive one catch pin therein when the flame holder is fitted over the end of the torch body. The flame holder is then manipulated until the catch pin(s) butt up against the end of the groove(s).
US08529245B1 Undercut mold insert
An undercut mold insert apparatus is disclosed for forming an undercut on an inner surface of a molded part. The apparatus provides, in an exemplary embodiment, a disk substantially shaped to approximate the dimensions of the object that is to be subsequently positioned within the undercut, the disk itself comprising an inner portion and a substantially circumferentially integral perimeter portion. The perimeter portion is configured for forming the undercut. The inner portion is configured for at least partially radially collapsing when appropriate force is applied thereto. As such, during the molding process, in which the apparatus is appropriately positioned within and subsequently forms the undercut of the molded part, upon cooling of the molded part, the inner portion is able to at least partially radially collapse, allowing substantially the entire perimeter portion to be disengaged from within the undercut before the apparatus is removed therefrom.
US08529244B2 Injection mold
An injection mold for molding a product having at least one bar formed at one side thereof. The injection mold includes a stationary mold including an inclined pillar and a movable mold including a movable core and a sliding block mounted on a top thereof. The inclined pillar inserted in the sliding block to drive the sliding block to slide towards or away from the movable core. A shaping cavity for molding the product is formed among the movable core, the sliding block and the stationary mold. The end surface of the sliding block further defines at least one shaping groove connected with the shaping cavity for molding the bar. The movable mold further includes an ejector pin and a maintaining pillar. The maintaining pillar resists against a bottom of the sliding block to avoid the ejector pin moving upward before the bar completely parted from the shaping groove.
US08529238B2 Container having a rim or other feature encapsulated by or formed from injection-molded material
A tool for creating a container or tray having various features. The tool comprises a cavity operable to receive a blank. The cavity has at least one sidewall for forming at least one sidewall of the container. A core is operatively connected to the cavity. The core is operable to enter the cavity to least partially form the blank into the container. An injection cavity is for receiving liquid resin and directing liquid resin around at least a portion of the perimeter of the blank. The injection cavity comprises an advanced-flow section and a delayed-flow section. The advanced-flow section has a greater cross-sectional area than the delayed-flow section, and the advanced-flow section is located adjacent the at least one sidewall of the cavity.
US08529233B2 Displacement machine with improved support
A displacement machine of spiral-type construction for a compressible medium includes a displacement body having a carrier disc and helical blades extending out from both sides of the carrier disc. The carrier disc has a hub which is supported by a hub bearing on an eccentric disc which is part of a driven drive shaft. The drive shaft is supported inside a housing by a first bearing and a second bearing. These bearings are arranged in receptacles which fully project into the feed chambers of the housing so that the bearings are positioned in close proximity to the eccentric disc.
US08529232B2 Compressor having capacity modulation system
A compressor includes first and second scroll members, a structure supporting the second scroll member, and a first piston. The first scroll member includes a first end plate and a first spiral wrap. The second scroll member includes a second end plate and a second spiral wrap engaged with the first spiral wrap to form compression pockets. The second end plate includes a first aperture in communication with a first compression pocket. The structure includes a first recess and first and second passages. The first piston is axially displaceable between first and second positions within the first recess. The first piston isolates the first passage from communication with the second passage when in the first and second positions, prevents communication between the first aperture and the first passage when in the first position, and provides communication between the first aperture and the first passage when in the second position.
US08529229B2 Ink jet printing apparatus
A tube pump reduced of the burden against pump driving caused by dragging of a tube by a pressurizing roller. Specifically, guide members are disposed in the respective introduction portions at between the guides. Namely, the guide members are arranged nearby the extensions of the circumference of the arcuate guides and radially with respect to the center of the circumference. Due to this, the pump tube, the roller is to drag, is sustained by the guide member, to prevent the tube from increasing its deformation due to dragging. Thus, the tube can be prevented from being dragged in a manner forming a resistance to the roller. As a result, the pump motor, etc. can be prevented from being burdened with an increasing load.
US08529227B2 Submersible pump capable of providing low voltage power supply
A submersible pump capable of providing low voltage power supply comprises a pump body and a filter cover connected to the pump body; a stator containing cavity and a rotor containing cavity is provided in the pump body; the outside of the rotor containing cavity is provided with an impeller room, and the upside of the impeller room is provided with a water outlet; a silicon steel sheet group of a stator and a stator coil are encapsulated in the stator containing cavity in the pump body; a permanent magnet rotor is fixed in the rotor containing cavity in the pump body via a rotor shaft; an impeller at one end of the permanent magnet rotor is located in the impeller room; it also comprises an internal transformer; the internal transformer is provided with a low voltage coil, and the stator coil acting as a high voltage coil, and the two coils are located at the silicon steel sheet group of the stator; the low voltage coil provides AC low voltage power supply to the outside. An internal transformer is constitute by the original silicon steel sheet group of the stator, the original stator coil, and an appended low voltage coil; this design occupies small room, and can provide AC or DC low voltage power supply to the outside as the submersible pump is working, so it is safe to use, and works reliably.
US08529225B2 Electromagnetic reciprocating fluid device
An electromagnetic reciprocating fluid device in which a movable member is equipped with permanent magnets, resists a torque rotating the movable member about an axis thereof in the reciprocating direction. The electromagnetic reciprocating fluid device has a pair of electromagnets facing each other, and permanent magnets disposed in a space between the opposed electromagnets and held by a movable member. When an alternating current is applied to coils formed in the electromagnets, a magnetic force is generated between the electromagnets and the permanent magnets, whereby a driving force for reciprocation is applied to the movable member. One end of the movable member is connected to a piston of a first piston-cylinder assembly, while the other end is connected to a piston of a second piston-cylinder assembly. The first and second piston-cylinder assemblies are arranged such that an axis line of the first piston-cylinder assembly and an axis line of the second piston-cylinder assembly are non-coaxial and vertically offset from an axis of the movable member.
US08529224B2 Hermetic compressor having auxiliary communication tube
A hermetic compressor for adjusting the length and cross sectional area of a communication path as a refrigerant flow passage, so as to attenuate a discharge pulsation and consequently, a vibration and noise thereof. The hermetic compressor, which includes a cylinder head having a discharge chamber to discharge a compressed refrigerant and a discharge muffler to receive the refrigerant discharged from the discharge chamber, further includes a communication path to communicate the discharge chamber and the discharge muffler with each other, so as to allow the refrigerant to flow from the discharge chamber into the discharge muffler, and an auxiliary communication tube to increase a length of the communication path for increasing a refrigerant flow distance. The auxiliary communication path reduces the cross sectional area of a refrigerant flow passage while increasing a refrigerant flow distance, thereby attenuating a low-frequency component of the discharge pulsation.
US08529221B2 Method and system for fuel control in a gas turbine engine
A fuel control system (100) for supplying metered fuel flow to a gas turbine engine is disclosed that includes a variable delivery fuel pump (116) for outputting a fuel flow that includes a burn fuel flow for the gas turbine engine and a surplus fuel flow recirculated back to an inlet (124) of the variable delivery fuel pump (116) and a pump control (148, 158, 122) for controlling the output of the variable delivery fuel pump to maintain the surplus fuel flow at a substantially constant rate. A method of controlling a fuel system (100) is also disclosed.
US08529216B2 Jet pump retention and seal method with living hinge
A fuel supply unit includes a fuel reservoir (22) for holding fuel. A fuel pump (18) is in the reservoir for pumping fuel from the reservoir. A jet pump assembly (16) is within the reservoir for drawing fuel from a fuel tank into the reservoir. A seal structure (24) has a flange (28) with a living hinge (31). The seal structure is operatively coupled with a housing of the jet pump assembly and disposed between the housing and a portion of the reservoir, with a portion of the flange being pivoted about the living hinge such that the portion of the flange engages an interior surface of the reservoir, providing a seal between the housing of the jet pump assembly and the interior surface of the reservoir.
US08529212B2 Multi-part modular airfoil section and method of attachment between parts
A fan system includes a motor, a rotatable hub, and a plurality of fan blades. Each of the fan blades includes a substantially rigid spine member, a resilient leading edge member, and a resilient trailing edge member. The leading edge member and trailing edge members are removably coupled with the spine member, such that different leading edge members and different trailing edge members may be chosen to customize the leading and trailing edges of the fan blades. Each fan blade may have more than one type of leading edge member or more than one type of trailing edge member. The leading edge member and trailing edge member may each be coupled with the spine member by urging the leading edge member and trailing edge member in a direction that is substantially perpendicular to the longitudinal axis defined by the spine member.
US08529211B2 Wind turbine rotor blade and airfoil section
The present invention includes a set of airfoils, U rails and V rails taken together to describe a blade for use with a horizontal axis wind turbine. The blade's design includes a maximum thickness higher than conventional blades employed for the same use thereby providing better load bearing structural characteristics while at the same time maintaining the requisite aerodynamic qualities for similar blades. The blade has a maximum thickness of about 30% and a maximum lift coefficient of about 1.3.
US08529199B2 Locking device
The invention relates to a locking device (13) that includes at least one locking system (16), intended to be placed on a first moving element (11), and a retaining member (17), intended to be placed on a second moving element (12), the locking system (16) having a first hook (18) designed to engage with the retaining member so as to lock the locking device (13). The locking system (16) includes at least a second hook (19) set back from the first hook (18) so as to engage with the retaining member in the event of the first hook (18) breaking.
US08529196B2 Nacelle equipped with at least one excess pressure flap
The present invention relates to a jet engine nacelle (1), of the type comprising an aft section forming an external structure (2) which, together with a concentric internal structure (4) comprising an internal panel (10) intended to surround a down-stream portion of the jet engine, defines an annular flow duct for a so-called secondary stream (3), characterized in that exhaust means (11) are formed in the internal panel such that any unwanted excess pressure is discharged into the annular duct.
US08529193B2 Gas turbine engine components with improved film cooling
An engine component includes a body; and a plurality of cooling holes formed in the body. At least one of the cooling holes has cross-sectional shape with a first concave portion and a first convex portion.
US08529192B2 Thrust bearing shaft for thrust and journal air bearing cooling in a compressor
A thrust bearing shaft has an enlarged disk at one axial end to provide a rotating surface in a thrust bearing. A first cylindrical portion extends from the disk. A second cylindrical portion has a smaller diameter than the first cylindrical portion and extends from the first cylindrical portion to an end of the thrust shaft remote from the disk. The thrust shaft has a hollow bore with a ledge extending across the bore at a location within the first cylindrical portion. The ledge is formed with a central hole of a first hole diameter, and twelve air holes spaced circumferentially about the central hole. The twelve holes are formed of a second hole diameter, with a ratio of the first hole diameter to the second hole diameter being between 2.55 and 2.71. In addition, a bearing assembly, a compressor, and a method of assembling a compressor are disclosed.
US08529190B2 Wind turbine rotor with vertical rotation axis
A wind turbine rotor with a vertical rotation axis connected to a hub having at least two horizontal supports, on the ends of which are tightly fixed blades, each consisting of two wings joined together, with a symmetrical or concavo-convex airfoil with the airfoil's chord lengths and thickness diminishing toward both wing ends. The rotor blade's upper and lower wings are radially deflected from the central zone outwards. The chord length of both wing ends and the chord length in the central zone are approximately inversely proportional to the radii of its location in relation to the axis of the rotor's rotation. The deflecting angle of the lower wing can be greater than the deflecting angle of the upper wing or the length of the lower wing can be greater than the length of the upper wing. These specifications provide uniform wind power consumption along the wing's length, increasing the efficiency of a wind turbine and its service life.
US08529188B2 Fan nacelle flow control
This disclosure relates to a gas turbine engine including a core engine that drives a fan. A fan nacelle surrounds the fan and provides an inner surface facing the fan. The fan nacelle includes an inlet lip adjoining the inner surface. A ring is arranged at the inner surface and is axially upstream from the fan. The ring includes a deployed position in which the ring is spaced radially inwardly from the inner surface to provide a gap therebetween through which air flows. The ring also includes a stowed position in which the ring is arranged radially inwardly from the deployed position and proximate to the inner surface. The ring is commanded to the deployed position in response to detecting a first condition, which corresponds to a flow separation condition at the fan nacelle inlet. The ring may be stowed during cruise conditions, for example.
US08529186B2 Collecting and transport device for a stack formed by layers of sheets
The invention relates to a collecting and conveying device for stacks of sheet layers, comprising a feed conveyor (1) for the sheet layers, —a collecting station (3) in which stacks (4) are formed by the layers of sheets, —a removal conveyor (7) for removing the completed stacks (4), and—a transfer unit for moving the stacks from the collecting station to the removal conveyor (7), wherein the collecting station comprises a series of support elements (6) and a series of delimiting and shaking elements (8), wherein the transfer unit comprises a series of sliding elements (10), wherein in each case a sliding element (10) together with a support element (6) and a delimiting and shaking element (8) can be adjusted transversely.
US08529184B1 Saddle rack lift mechanism
According to the present invention, there is provided a lift mechanism adapted for movement between a substantially horizontal position and a substantially vertical position. At least one saddle rack adapted to carry a horse saddle is combined to the lift mechanism and positively rotates with respect to the lift mechanism in rotational synchronization with the movement of the lift mechanism as the lift mechanism moves between the respective positions, such that the horse saddle is held in a substantially upright position throughout the lift mechanism's movement.
US08529183B2 Vehicle restraint system
The invention relates to a system for restraining a vehicle at a loading dock, having a base, an arm rotatably mounted to the base for rotating between a lowered position out of contact with the vehicle, a partially elevated position and an upright position for contacting the vehicle to restrain the vehicle in a position suitable for loading or unloading, an arm rotator, a position sensor to detect the rotational position of the arm, a lock and a lock actuator for locking the arm, and a controller in operative communication with the position sensor for determining the position of the vehicle relative to the dock upon contact between the arm and the vehicle for actuating the lock to retain the arm in the upright position to restrain the vehicle.
US08529178B2 Weldless building structures
A building structure including a first building member and a second building member may be connected by a plurality of fasteners, each fastener having a head, a threaded portion having a through hardness of between HRB 70 and HRC 40, a thread-forming portion of at least HRC 50 hardness enabling the fastener to form threads in at least the second steel building member, and a fluted lead portion of at least HRC 50 hardness with a nominal diameter between 70 and 95% of major diameter, such that the fastener is capable of providing a ratio of strip torque to thread-forming torque of at least 3.0 and a ratio of strip torque to drive torque greater than 6.0 when the second steel building member having a thickness of 0.25 inch and the fluted lead portion having at least one diameter within nominal diameter between 80 and 98% of major diameter.
US08529169B2 Drilling tool with dust collector
According to the invention, a drilling tool includes: a motor; a transmission drive unit for transmitting a rotation force of the motor to rotate a drill bit; and a dust collector for collecting dust produced from a workpiece drilled by the drill bit, wherein the dust collector is provided with a pierced portion pierced by the drill bit, a dust collection port for sucking the produced dust and its surrounding air, and a blowoff port for blowing air against a vicinity of the piercing drill bit.
US08529166B2 Cutting tool and cutting insert therefor
An indexable cutting insert has opposing side surfaces and two cutting portions, one of which is operative when the cutting insert is retained in an insert holder. An insert bore opens out to both side surfaces. Two major abutment surfaces located on opposite sides of the insert bore extend from one of the side surfaces, one major abutment surface being closer to the operative cutting portion than the other. Two minor abutment surfaces extend from the same side surface. In a plan view of the side surface, the minor abutment surfaces are transverse to the two major abutment surfaces and also to base abutment surfaces associated with the major and minor abutment surfaces.
US08529155B2 Method of making pure salt from frac-water/wastewater
The present invention relates to a method for making pure salt comprises recapturing post-drilling flowback water from hydro-fracturing; removing oil from the flowback water; filtering the flowback water using an ultra filter with a pore size of about 0.1 microns or less to remove solid particulates and large organic molecules, such as benzene, ethylbenzene, toluene, and xylene, from the water; concentrating the flowback water to produce a brine that contains from about 15 wt % to about 40 wt % of salt relative to the total weight of the flowback brine; performing one or more chemical precipitation process using an effective amount of reagents to precipitate out the desired high quality commercial products, such as, barium sulfate, strontium carbonate, calcium carbonate; and crystallizing the chemically treated and concentrated flowback brine to produce greater than 99.5% pure salt products, such as sodium and calcium chloride.
US08529152B1 Resistive braking via screed heating
A method and various apparatus are provided for assisting braking in a paving machine having hydraulically driven ground engaging elements driven by a hydraulic motor, and one or more screed electrical heating elements powered by a generator. In the event that the application of the machine deceleration system occurs at a machine speed exceeding a predetermined threshold value, the hydraulic motor of the drive train is configured to drive the hydraulic pump of the hydraulic system. The hydraulic pump is linked to the system generator to generate electrical power to drive the one or more screed electrical heating elements at a current greater than the current previously being provided to the one or more screed electrical heating elements.
US08529150B2 Toothbrush device
A toothbrush device having a body defining a cavity and an input port disposed on the body in fluid communication with the cavity. The input port permits brushing by-products to pass through the input port and into the cavity while restricting passage of the brushing by-products outward from the cavity. In one form, the toothbrush device includes an elongated handle with a reservoir having at least a portion disposed within the handle. The reservoir is sized to hold a predetermined amount of oral care product, and a mouthpiece is in fluid communication with the reservoir to discharge the oral care product from the reservoir.
US08529148B2 Painting device
A device for applying paint includes a paint applicator and a guiding means, the guiding means consists of two guiding rollers, the axis of rotation of each roller being fixed in use such that the two axes are disposed at an angle to one another in the range from 50° to 130° . The device is particularly suitable for applying paint in a linear strip of predetermined width along architectural objects such as window sills and sashes, lintels and beams.