最新美国发明专利第2013-07-16期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08487491B2	Insulating retaining element for phase potential bars A stator for an electric motor has phase potential bars and an insulating retaining element. The insulating retaining element includes a first component configured to accommodate the phase potential bars and to insulate the phase potential bars electrically from one another. The insulating retaining element additionally includes a second component which is separate from the first component. The second component, in conjunction with the first component, forms a trough that borders on the phase potential bars.
US08487489B2	Apparatus for cooling an electric machine Provided is an apparatus, for example, for use with a rotating electric machine, that includes a housing. The housing can include a housing main portion and a housing end portion. The housing main portion can be configured to be disposed proximal to a body portion of a stator section of an electric machine. The housing main portion can define a main fluid channel that is configured to conduct fluid therethrough. The housing end portion can receive fluid from said main fluid channel and direct fluid into contact with a winding end portion of a conductive winding of the stator section.
US08487485B2	Linear synchronous motor A linear synchronous motor is provided, of which a core unit may readily be manufactured. Accordingly, the manufacturing cost of the linear synchronous motor may be reduced, and the weight of the linear synchronous motor may be lightened. The linear synchronous motor includes a frame member that is formed of a magnetic conductive material and surrounds the periphery of a core unit centering on a shaft. The frame member functions as a yoke that magnetically connects a plurality of magnetic pole portions. The frame member is constituted from a first divided frame member and a second divided frame member fixed to the core unit with screws.
US08487484B1	Permanent magnet drive apparatus and operational method A magnetic drive apparatus includes first and second magnet carriers carrying first and second permanent magnet arrangements. An intermediate magnet carrier disposed between the first and second magnet carriers carries a third permanent magnet arrangement. The magnet carriers are arranged for rotation relative to each other such that the magnet arrangements produce magnetic interactions that result in power stroke forces causing the magnet carriers to undergo relative reciprocation in first and second stroke directions during power zone portions of the relative rotation. The magnetic interactions impart substantially no power stroke forces during dead zone portions of the relative rotation. The dead zones include magnet carrier relative rotation positions wherein opposing magnetic poles are mutually coaxially aligned but produce a substantially equal balance of push and pull magnetic forces. The apparatus may be synchronized so that the dead zones coincide with top dead center and bottom dead center relative reciprocation positions.
US08487481B2	Wireless power transmission for electronic devices Exemplary embodiments are directed to wireless power transfer. A wireless power receiver includes a receive antenna for coupling with a transmit antenna of transmitter generating a magnetic near field. The receive antenna receives wireless power from the magnetic near field and includes a resonant tank and a parasitic resonant tank wirelessly coupled to the resonant tank. A wireless power transmitter includes a transmit antenna for coupling with a receive antenna of a receiver. The transmit antenna generates a magnetic near field for transmission of wireless power and includes a resonant tank and a parasitic resonant tank coupled to the resonant tank.
US08487479B2	Ferrite antennas for wireless power transfer This disclosure provides systems, methods and apparatus for wireless power transfer using resonant ferrite antennas to transmit and receive power. Ferrite structures concentrate magnetic flux lines into the structure, thereby creating a magnetic path and field with less interference and eddy current losses than in device electronics, thereby improving the efficiency of magnetic power distribution. The disclosure describes tuning the resonance frequency by mechanically adjusting the position of the coil on the rod. The ferrite rod antennas described herein may be used to transfer power to handheld communication devices.
US08487475B2	Power supply apparatus and method of supplying power A power supply apparatus, an apparatus, and a method of supplying power are provided. The power supply apparatus including a high voltage generating unit, which generates one or more output voltages by using an input voltage, and which is implemented as a chip. The one or more output terminals are on a same circuit board as the high voltage generating unit, to output the generated one or more output voltages. The chip includes a transforming unit to transform the input voltage into one or more transformed voltages that are different from one another, and a rectifying unit to rectify the transformed voltages into rectified voltages, and to determine the rectified voltages as the generated one or more output voltages.
US08487471B2	Floating wind turbine with turbine anchor The wind turbine 20 includes a wind driven turbine wheel 22 rotatable about a central axis 29 that has sail wings 30 that catch the wind and rotate the turbine wheel 22. An anchor 58 has its anchor line 56 attached to the turbine wheel at its axis of rotation 29 to prevent tilting the wind turbine in response to high wind conditions.
US08487469B2	Solar wind tree An apparatus for generating electrical power. The apparatus comprises a plurality of solar energy collectors for generating electricity from solar energy; a plurality of wind turbines for generating electricity from wind energy; a support structure having arms extending radially from a vertical shaft, the arms positioned at different vertical distances along the vertical shaft and the arms having different lengths; solar energy collectors and the wind turbines affixed to terminal ends of the arms; and the support structure comprising camouflage elements causing the support structure to resemble vegetation.
US08487468B2	Turbine system and method Some embodiments of a turbine system described herein provide a turbine that rotates in response to off-axis fluid flow, such as water flowing in a generally horizontal direction that is generally perpendicular to a vertical axis of rotation. The rotation of the turbine can drive a generator to output electrical energy.
US08487463B2	Enhanced multi-mode power generation system An enhanced multi-mode power generation system harnesses solar energy, wind, and heat within a designed building or within a large enclosed area, providing an indoor system to generate electricity. Air within an enclosure is heated, either by solar energy or by use of an electrified exothermic heating material, to enhance the airflow velocity within the enclosure. A system of narrowed passageways within the enclosure further increases the airflow velocity, which enhancement may also include or be supplemented by a blower. The enhanced velocity air is passed through one or multiple-staged wind turbines to generate electrical power.
US08487462B2	Methods for controlling a wind turbine connected to the utility grid, wind turbine and wind park Methods for controlling a wind turbine connected to the utility grid by detecting status of the utility grid, and controlling one or more rotor blades and/or emitted power to the grid in returning to the operational wind turbine settings of normal grid mode, as well as wind turbines and wind parks comprising at least two wind turbines.
US08487460B2	Wind energy installation with individual pitch devices Provided herein is a wind energy installation including a generator for production of electrical energy, a rotor which drives the generator and has variable pitch rotor blades and a central control device, and individual pitch devices provided individually for the rotor blades. The individual pitch devices may include an adjustment drive, a communication link to the central control device and a regulator, the rotor blades being adjustable in order to slow down the wind energy installation to a shut-down position. The individual pitch devices may also include a disturbance situation detector which is designed to identify abnormal operating states and to move the rotor blades to a shut-down position. Also provided herein is the method of operating such a wind energy installation.
US08487457B2	Engine system To provide an engine system with which in a case where a power supply voltage whose specification is to be changed is higher than an expected voltage, the specification of the power supply voltage from an alternating-current power supply can be changed at low cost without providing an additional transformer.An engine system 100 includes a transformer 130, a power receiving device 140, and a switcher 150, and switcher 150 connects a switching terminal 151 connected to one power receiving terminal 141 of the power receiving device 140 to either a first terminal 152 connected to one terminal 134 of a primary 131 or a second terminal 153 connected to a branch terminal 136. The engine system 100 is configured such that the other power receiving terminal 142 of the power receiving device 140 and the other terminal 135 of the primary 131 are connected and the primary 131 and an alternating-current power supply 200 are electrically connected.
US08487451B2	Lead frame land grid array with routing connector trace under unit A package includes a first plated area, a second plated area, a die attached to the first plated area, and a bond coupling the die to the second plated area. The package further includes a molding encapsulating the die, the bond, and the top surfaces of the first and second plated areas, such that the bottom surfaces of the first and second plated areas are exposed exterior to the package. Additional embodiments include a method of making the package.
US08487448B2	Method for producing chip packages, and chip package produced in this way A method for producing chip packages is disclosed. In one embodiment, a plurality of chips is provided. The chips each have first pads. Second connection pads are applied on the wafer, wherein each second pad is electrically connected to a first pad.
US08487446B2	Method of embedding passive component within via A method of forming a device associated with a via includes forming an opening or via, and forming at least a pair of conducting paths within the via. Also disclosed is a via having at pair of conducting paths therein.
US08487443B2	Semiconductor structure, manufacturing method of semiconductor structure and semiconductor device Disclosed is a semiconductor structure including a semiconductor substrate including an electronic circuit which is provided in a predetermined region of the semiconductor substrate, a wiring provided on the semiconductor substrate in a region outside of the predetermined region, an external connection electrode provided on the wiring, a sealing resin which covers a side surface of the external connection electrode and a wall which intervenes between the electronic circuit and the sealing resin.
US08487441B2	Rigid wave pattern design on chip carrier substrate and printed circuit board for semiconductor and electronic sub-system packaging A rigid wave pattern formed on a first side of a substrate in a semiconductor die package. The rigid wave pattern aligns with and overlies the contact fingers formed on the second side of the substrate. The rigid wave pattern includes a first pattern with an etched portion and an unetched portion around the etched portion. When the substrate and dice are encased during the molding process, the rigid wave pattern effectively reduces deformation of and stresses on the dice, therefore substantially alleviating die cracking.
US08487431B2	Semiconductor integrated circuit having a multi-chip structure A semiconductor integrated circuit having a multi-chip structure includes a plurality of stacked semiconductor chips. At least one of the semiconductor chips includes first and second metal layers separately formed inside the semiconductor chip, a first internal circuit coupled in series between the first and second metal layers inside the semiconductor chip, a first metal path vertically formed over the second metal layer to a first side of the semiconductor chip, and a first through silicon via formed through the semiconductor chip from a second side of the semiconductor chip to the first metal layer.
US08487430B1	Multi-layer high-speed integrated circuit ball grid array package and process Examples of high-speed ball grid array packages and a process of forming a package are provided. A package may include contact pads disposed on a bottom surface, conductive balls, and a signal via structure. The package may also include a first ground via structure arranged along one or more first semi-circular contours around the signal via structure and extending vertically and a second ground via structure arranged along one or more second semi-circular contours around the signal via structure and extending vertically. The package may include a ground interface plane disposed in separation from the signal contact pad by a distance. The distance may be determined based on at least a size of the signal contact pad, a dielectric constant of a transition layer between the ground interface plane and the signal contact pad, and a distance between the signal via structure and the second ground via structure.
US08487425B2	Optimized annular copper TSV The present disclosure provides a thermo-mechanically reliable copper TSV and a technique to form such TSV during BEOL processing. The TSV constitutes an annular trench which extends through the semiconductor substrate. The substrate defines the inner and outer sidewalls of the trench, which sidewalls are separated by a distance within the range of 5 to 10 microns. A conductive path comprising copper or a copper alloy extends within said trench from an upper surface of said first dielectric layer through said substrate. The substrate thickness can be 60 microns or less. A dielectric layer having interconnect metallization conductively connected to the conductive path is formed directly over said annular trench.
US08487422B2	Chip stack with conductive column through electrically insulated semiconductor region A method for stacking and interconnecting integrated circuits includes providing at least two substrates; forming a trench in each substrate; filling the trench with an insulating material; forming, in each substrate, at least one conductive area; thinning each substrate until reaching at least the bottom of the trench, to obtain in each substrate at least one electrically insulated region within the closed perimeter delineated by the trench; bonding the substrates together; making at least one hole through the bonded substrates so that the hole passes at least partially through the conductive areas and passes through the insulated region of each substrate; and filling the hole with an electrically conductive material so as to obtain a conductive column that traverses the isolated region of each substrate and is in lateral electrical contact with the conductive areas.
US08487421B2	Microelectronic package with stacked microelectronic elements and method for manufacture thereof A microelectronic package may include a stacked microelectronic unit including at least first and second vertically stacked microelectronic elements each having a front face facing a top surface of the package. The front face of the first element may be adjacent the top surface, and the first element may overlie the front face of the second element such that at least a portion of the front face of the second element having an element contact thereon extends beyond an edge of the first element. A conductive structure may electrically connect a first terminal at the top surface to an element contact at the front face of the second element, and include a continuous monolithic metal feature extending along the top surface and through at least a portion of an encapsulant, which is between the top surface and the front face of the second element, towards the element contact.
US08487420B1	Package in package semiconductor device with film over wire In accordance with the present invention, there is provided multiple embodiments of a package-in-package semiconductor device including shortened electrical signal paths to optimize electrical performance. The semiconductor device comprises a substrate having a conductive pattern formed thereon. In each embodiment of the semiconductor device, a semiconductor package and one or more semiconductor dies are vertically stacked upon the substrate, and placed into electrical communication with the conductive pattern thereof. In certain embodiments, a semiconductor die which is electrically connected to the conductive pattern of the substrate may be fully or partially covered with a film-over-wire. Additionally, in each embodiment of the semiconductor device, the vertically stacked electronic components thereof may be covered with a package body which also partially covers the substrate.
US08487404B2	Fuse patterns and method of manufacturing the same The present invention provides fuse patterns and a method of manufacturing the same. According to the present invention, an insulating layer and a contact plug are filled between fuse patterns which are formed to have their ends broken and are isolated from each other. In case of a fail cell, the insulating layer is broken owing a difference in an electrical bias (current or voltage) between a metal wire and the fuse patterns, and a short is generated between the fuse patterns. Accordingly, embodiments avoid damage to a semiconductor substrate associated with a conventional fuse repair method employing laser energy, and the area of a fuse box can be reduced.
US08487402B2	Semiconductor device The semiconductor device which has an electric straight line-like fuse with a small occupying area is offered.A plurality of projecting portions 10f are formed in the position shifted from the middle position of electric fuse part 10a, and, more concretely, are formed in the position distant from via 10e and near via 10d. A plurality of projecting portions 20f are formed in the position shifted from the middle position of electric fuse part 20a, and, more concretely, are formed in the position distant from via 20d and near 20e. That is, projecting portions 10f and projecting portions 20f are arranged in the shape of zigzag.
US08487401B2	Methods of fabricating passive element without planarizing and related semiconductor device Methods of fabricating a passive element and a semiconductor device including the passive element are disclosed including the use of a dummy passive element. A dummy passive element is a passive element or wire which is added to the chip layout to aid in planarization but is not used in the active circuit. One embodiment of the method includes forming the passive element and a dummy passive element adjacent to the passive element; forming a dielectric layer over the passive element and the dummy passive element, wherein the dielectric layer is substantially planar between the passive element and the dummy passive element; and forming in the dielectric layer an interconnect to the passive element through the dielectric layer and a dummy interconnect portion overlapping at least a portion of the dummy passive element. The methods eliminate the need for planarizing.
US08487400B2	High performance system-on-chip using post passivation process The present invention extends the above referenced continuation-in-part application by in addition creating high quality electrical components, such as inductors, capacitors or resistors, on a layer of passivation or on the surface of a thick layer of polymer. In addition, the process of the invention provides a method for mounting discrete electrical components at a significant distance removed from the underlying silicon surface.
US08487396B2	Trench sidewall contact Schottky photodiode and related method of fabrication A Schottky photodiode may include a monocrystalline semiconductor substrate having a front surface, a rear surface, and a first dopant concentration and configured to define a cathode of the Schottky photodiode, a doped epitaxial layer over the front surface of the monocrystalline semiconductor substrate having a second dopant concentration less than the first dopant concentration, and parallel spaced apart trenches in the doped epitaxial layer and having of a depth less than a depth of the doped epitaxial layer. The Schottky photodiode may include a metal filler in the parallel spaced apart trenches to form a Schottky rectifying contact with the doped epitaxial layer, an anode current distributor metal layer on a surface of the doped epitaxial layer and in electrical contact with the metal filler of the parallel spaced apart trenches, a dielectric passivation layer on the anode current distributor metal layer, and a conductive metal layer over the rear surface of the monocrystalline semiconductor substrate and configured to provide an ohmic contact with the cathode.
US08487386B2	Method for forming MEMS devices having low contact resistance and devices obtained thereof The present disclosure proposes a method for manufacturing in a MEMS device a low-resistance contact between a silicon-germanium layer and a layer contacted by this silicon-germanium layer, such as a CMOS metal layer or another silicon-germanium layer, through an opening in a dielectric layer stack separating both layers. An interlayer is formed in this opening, thereby covering at least the sidewalls of the opening on the exposed surface of the another layer at the bottom of this opening. This interlayer may comprise a TiN layer in contact with the silicon-germanium layer. This interlayer can further comprise a Ti layer in between the TiN layer and the layer to be contacted. In another embodiment this interlayer comprises a TaN layer in contact with the silicon-germanium layer. This interlayer can then further comprise a Ta layer in between the TaN layer and the layer to be contacted.
US08487384B2	Semiconductor device, power-supply unit, amplifier and method of manufacturing semiconductor device A semiconductor device, includes a semiconductor layer formed above a substrate; an insulating film formed on the semiconductor layer; and an electrode formed on the insulating film. The insulating film has a membrane stress at a side of the semiconductor layer lower than a membrane stress at a side of the electrode.
US08487383B2	Flash memory device having triple well structure A flash memory device, including a cell array region where a plurality of memory cells are connected in series to a single cell string, the cell array region including a pocket p-well configured to accommodate the plurality of memory cells and an n-well configured to surround the pocket p-well, a first peripheral region where low-voltage (LV) and high-voltage (HV) switches are connected to the memory cells through a word line, and a second peripheral region where bulk voltage switches are connected to bulk regions of the LV and HV switches.
US08487379B2	Structure and method for buried inductors for ultra-high resistivity wafers for SOI/RF SiGe applications A design structure is embodied in a machine readable medium for designing, manufacturing, or testing a design. The design structure includes a high resistivity substrate and a buried inductor formed directly in the high resistivity substrate and devoid of an insulating layer therebetween.
US08487378B2	Non-uniform channel junction-less transistor The present disclosure discloses a method of forming a semiconductor layer on a substrate. The method includes patterning the semiconductor layer into a fin structure. The method includes forming a gate dielectric layer and a gate electrode layer over the fin structure. The method includes patterning the gate dielectric layer and the gate electrode layer to form a gate structure in a manner so that the gate structure wraps around a portion of the fin structure. The method includes performing a plurality of implantation processes to form source/drain regions in the fin structure. The plurality of implantation processes are carried out in a manner so that a doping profile across the fin structure is non-uniform, and a first region of the portion of the fin structure that is wrapped around by the gate structure has a lower doping concentration level than other regions of the fin structure.
US08487376B2	High-voltage transistor architectures, processes of forming same, and systems containing same An apparatus includes a first device with a metal gate and a drain well that experiences a series resistance that drops a drain contact voltage from 10 V to 4-6 V at a junction between the drain well and a channel under the gate. The apparatus includes an interlayer dielectric layer (ILD0) disposed above and on the drain well and a salicide drain contact in the drain well. The apparatus also includes a subsequent device that is located in a region different from the first device that operates at a voltage lower than the first device.
US08487375B2	Semiconductor device and method of manufacturing semiconductor device A semiconductor device includes a compound semiconductor layer provided over a substrate, a plurality of source electrodes and a plurality of drain electrodes provided over the compound semiconductor layer, a plurality of first vias each of which is configured to pass through the compound semiconductor layer and be coupled to a corresponding one of the plurality of source electrodes, a plurality of second vias each of which is configured to pass through the compound semiconductor layer and be coupled to a corresponding one of the plurality of drain electrodes, a common source wiring line configured to be coupled to the plurality of first vias and be buried in the substrate, and a common drain wiring line configured to be coupled to the plurality of second vias and be buried in the substrate.
US08487372B1	Trench MOSFET layout with trenched floating gates and trenched channel stop gates in termination A trench MOSFET layout with multiple trenched floating gates and at least one trenched channel stop gate in termination area shorted with drain region is disclosed to make it feasibly achieved after die sawing. The layout consisted of dual trench MOSFETs connected together with multiple sawing trenched gates across a space between the two trench MOSFETs having a width same as scribe line.
US08487371B2	Vertical MOSFET transistor having source/drain contacts disposed on the same side and method for manufacturing the same Systems and methods of fabricating Wafer Level Chip Scale Packaging (WLCSP) devices with transistors having source, drain and gate contacts on one side of the transistor while still having excellent electrical performance with low drain-to-source resistance RDS(on) include using a two-metal drain contact technique. The RDS(on) is further improved by using a through-silicon-via (TSV) technique to form a drain contact or by using a copper layer closely connected to the drain drift.
US08487367B2	Planar MOSFET with textured channel and gate A semiconductor device is disclosed that includes a semiconductor substrate having a channel region and respective source and drain regions formed on opposite sides of the channel region. The channel region includes at least one pore. A gate is formed on the semiconductor substrate between the source and drain regions and includes at least one pin received by respective ones of the at least one pore. A dielectric layer is disposed between the gate and the semiconductor substrate.
US08487365B2	Semiconductor device and method for manufacturing same According to one embodiment, a semiconductor device includes a substrate, a lower gate layer, a stacked body, a dummy electrode layer, an insulating film, and a channel body. The lower gate layer is provided above the substrate. The stacked body includes a plurality of insulating layers and a plurality of electrode layers alternately stacked above the lower gate layer. The dummy electrode layer is provided between the lower gate layer and the stacked body, made of the same material as the electrode layer, and thicker than each of the electrode layers. The insulating film includes a charge storage film provided on a side wall of a hole formed to penetrate through the stacked body and the dummy electrode layer. The channel body is provided on an inside of the insulating film in the hole.
US08487363B2	Method for manufacturing semiconductor device The present invention relates to a method for manufacturing a semiconductor device, and provides to reduce a contact resistance of a landing plug by forming the landing plug in such a manner that a polysilicon layer is deposited only on the surface of a landing plug contact hole, and a metal layer is buried in the rest of the landing plug contact hole in the process of forming a storage node contact or a bit line contact.
US08487362B2	Semiconductor device and method of forming the same A semiconductor device includes a semiconductor substrate having first and second regions, a first pillar transistor, and a second pillar transistor, wherein the first pillar transistor comprises a first semiconductor pillar disposed in the first region, and a first gate electrode covering a side surface of the first semiconductor pillar, wherein the second pillar transistor comprises a second semiconductor pillar disposed in the second region, and a second gate electrode covering a side surface of the second semiconductor pillar, wherein the first gate electrode is different in height from the second gate electrode, and the first and second pillar transistors form a CMOS device.
US08487360B2	Semiconductor memory devices with high gate coupling ratio and methods of manufacturing the same A semiconductor memory device includes a substrate of a first impurity type, a first well region of a second impurity type in the substrate, the second impurity type being different from the first impurity type, a second well region of the first impurity type in the substrate, a patterned first dielectric layer on the substrate extending over the first and second well regions, a patterned first gate structure on the patterned first dielectric layer, a patterned second dielectric layer on the patterned first gate structure, and a patterned second gate structure on the patterned second dielectric layer. The patterned first gate structure may include a first section extending in a first direction and a second section extending in a second direction orthogonal to the first section, wherein the first section and the second section intersects each other in a cross pattern. The patterned second gate structure may include at least one of a first section extending in the first direction over the first section of the patterned first gate structure or a second section extending in the second direction over the second section of the patterned first gate structure.
US08487359B2	Spin MOSFET and reconfigurable logic circuit using the spin MOSFET It is made possible to provide a spin MOSFET that can minimize the increase in production costs and can perform both spin injection writing and reading. A spin MOSFET includes: a substrate that has a semiconductor region of a first conductivity type; first and second ferromagnetic stacked films that are formed at a distance from each other on the semiconductor region, and each have the same stacked structure comprising a first ferromagnetic layer, a nonmagnetic layer, and a second ferromagnetic layer stacked in this order, the second ferromagnetic stacked film having a film-plane area different from that of the first ferromagnetic stacked film; a gate insulating film that is formed on a portion of the semiconductor region, the portion being located between the first ferromagnetic stacked film and the second ferromagnetic stacked film; and a gate that is formed on the gate insulating film.
US08487357B2	Solid state imaging device having high sensitivity and high pixel density Each pixel of a solid state imaging device comprises: a first semiconductor layer; a second semiconductor layer; a third semiconductor layer and fourth semiconductor layer formed on the lateral side of the upper region of the second layer not to be in contact with the top surface of the second semiconductor layer; a gate conductor layer formed on the lower side of the second semiconductor layer; a conductor electrode formed on the side of the fourth semiconductor layer via an insulating film; and a fifth semiconductor layer formed on the top surface of the second semiconductor layer, wherein at least the third semiconductor layer, upper region of the second semiconductor layer, fourth semiconductor layer, and fifth semiconductor layer are formed in the shape of an island. A specific voltage is applied to the conductor electrode to accumulate holes in the surface region of the fourth semiconductor layer.
US08487356B2	Graphene device and method of manufacturing the same The graphene device may include an upper oxide layer on at least one embedded gate, and a graphene channel and a plurality of electrodes on the upper oxide layer. The at least one embedded gate may be formed on the substrate. The graphene channel may be formed on the plurality of electrodes, or the plurality of electrodes may be formed on the graphene channel.
US08487352B2	Metal oxide semiconductor (MOS) transistors having a recessed gate electrode A metal oxide semiconductor (MOS) includes an isolation layer disposed in a semiconductor substrate to define an active region. A source region and a drain region are disposed on both sides of the active region such that a first direction is defined from the source region to the drain region. A channel recess is disposed in the active region between the source and drain regions. The channel recess has a convex surface when viewed from a cross-sectional view taken along a second direction orthogonal to the first direction. A gate electrode fills the channel recess and crosses the active region in the second direction. A gate insulating layer is interposed between the gate electrode and the active region.
US08487347B2	Array substrate and manufacturing method thereof An array substrate comprises a substrate provided with a circuit pattern and covering layers that cover the upper surfaces and side surfaces of respective portions of the circuit pattern.
US08487346B2	Semiconductor device A semiconductor device including: a substrate, which has a composition represented by the formula: Ala′Ga1-a′N, wherein a′ satisfies 0
US08487345B2	Information recording and reproducing device According to one embodiment, an information recording and reproducing device includes a stacked body. The stacked body includes a first layer, a second layer and a recording layer provided between the first layer and the second layer. The recording layer includes a phase-change material and a crystal nucleus. The phase-change material is capable of reversely changing between a crystal state and an amorphous state by a current supplied via the first layer and the second layer. The crystal nucleus is provided in contact with the phase-change material and includes a crystal nucleus material having a crystal structure identical to a crystal structure of the crystal state of the phase-change material, and a crystal nucleus coating provided on a surface of the crystal nucleus material and having a composition different from a composition of the crystal nucleus material.
US08487344B2	Optical device and method of fabricating the same Disclosed is an optical device including an optical member and a contact layer stacked on at least one of top and bottom surfaces of the optical member. The contact layer has at least one transparent conducting oxynitride (TCON) layer. The TCON consists of at least one of indium (In), tin (Sn), zinc (Zn), cadmium (Cd), gallium (Ga), aluminum (Al), magnesium (Mg), titanium (Ti), molybdenum (Mo), nickel (Ni), copper (Cu), silver (Ag), gold (Au), platinum (Pt), rhodium (Rh), iridium (Ir), ruthenium (Ru), and palladium (Pd).
US08487342B2	Semiconductor device and manufacturing method thereof A separation layer containing a halogen element is formed over a glass substrate by a plasma CVD method; a semiconductor element is formed over the separation layer; and separation is then performed inside the separation layer or at its interface, so that the large-area glass substrate and the semiconductor element are detached from each other. In order to perform detachment at the interface between the glass substrate and the separation layer, the separation layer may have concentration gradient of the halogen element, and the halogen element is contained more near the interface between the separation layer and the glass substrate than in the other areas.
US08487340B2	Optoelectronic device based on nanowires and corresponding processes The invention relates to a method for making optoelectronic devices comprising nanowire semiconductors, in which: the nanowires (2) are formed on a substrate (1), said nanowires being capable of emitting a light beam; a first electric contact area is formed at the substrate, and a second electric contact area is formed at the nanowires, characterized in that the second electric contact area is formed on the edge of the nanowires (2) in direct contact with said nanowires, on a predetermined height (h) thereof and in the vicinity of their end opposite the substrate, as well as between said nanowires, the upper surface (20) of the nanowires being exposed.
US08487339B2	Light-emitting diode chip package body and method for manufacturing same A light-emitting diode chip package body with an excellent heat dissipation performance and a low manufacturing cost, and a packaging method of the same are disclosed. A LED chip package body is provided, the LED chip package body comprising: a LED chip having an electrode-side surface and at least two electrodes mounted on said electrode-side surface; an electrode-side insulating layer formed on said electrode-side surface of said LED chip and formed with a plurality of through-holes registered with corresponding said electrodes; a highly heat-dissipating layer formed in each of said through-holes of said insulating layer on said electrode-side surface; and a highly heat-conducting metal layer formed on said highly heat-dissipating layer in each of said through-holes.
US08487335B2	Light emitting device, illumination apparatus and display apparatus Disclosed herein is a light emitting device including: an organic layer sandwiched between a first electrode and a second electrode to serve as an organic layer including a light emitting layer for emitting monochromatic light at one location; a first light reflection boundary face provided on a side close to the first electrode to serve as a boundary face for reflecting light emitted from the light emitting layer so as to radiate the reflected light from a side close to the second electrode; and a second light reflection boundary face, a third light reflection boundary face and a fourth light reflection boundary face which are sequentially provided at positions separated away from each other in a direction from the first electrode to the second electrode on the side close to the second electrode.
US08487329B2	Light-emitting component having a wavelength converter and production method A conversion layer (5) is vapor-deposited onto the light-emitting surface. The conversion layer (5) may comprise a vapor-depositable matrix material and a vapor-depositable converter material, which may in particular both comprise low molecular weight organic compounds. A multilayer structure (3), which contains the layers provided for generating radiation, may likewise be built up from low molecular weight organic compounds, such that all the compounds may be applied in the same vapor deposition installation.
US08487323B2	LED housing system An LED housing having a housing cavity, a carrier element, LED chips, the LED housing being formed in such a way that it may connect a plurality of LED housings of identical construction and, by its shaping, is additionally mountable in various ways.
US08487321B2	AC light emitting assembly and AC light emitting device An alternating current (AC) light emitting assembly and an AC light emitting device are disclosed. The AC light emitting assembly includes a substrate; a rectifier unit comprising a plurality of rectifier components arranged in a Wheatstone Bridge, for rectifying an AC signal into a direct current (DC) signal, each of the rectifier components having a high breakdown voltage and a low forward voltage; a light emitting unit electrically connected to the rectifier unit and comprising a plurality of light emitting components formed on the substrate, for emitting light when receiving the DC signal outputted by the rectifier unit; and two conductive electrodes electrically connected to the rectifier unit for receiving and transmitting the AC signal to the rectifier unit. The AC light emitting device includes two stacked and electrically connected AC light emitting assemblies.
US08487318B2	Semiconductor device and manufacturing method thereof A semiconductor device of the present invention includes a semiconductor layer composed of SiC, a metal layer directly bonded to one face of the semiconductor layer, and a high carbon concentration layer formed on a surface layer portion at one side of the semiconductor layer and containing more highly concentrated carbon than a surface layer portion of the other side. Further, a manufacturing method of a semiconductor device of the present invention includes the steps of forming, on a surface layer portion at one face side of a semiconductor layer composed of SiC, a high carbon concentration layer containing more highly concentrated carbon than a surface layer portion at the other face side by heat treatment and directly bonding metal to the high carbon concentration layer.
US08487315B2	Illumination apparatus A point light source is converted into a plane light source having a satisfactory uniformity. The point light source is converted into a line light source by means of a linear light guiding plate, and further into the plane light source by means of a plane-like light guiding plate. Light from the point light source is reflected at a lamp reflector to be incident on at least two side surfaces of the plane-like light guiding plate.
US08487310B2	Organic light-emitting display apparatus An organic light-emitting display apparatus comprises: a substrate in which a pixel region is defined; a thin film transistor (TFT) disposed on the substrate and spaced apart from the pixel region; a planarization pattern covering the TFT and spaced apart from the pixel region; a first electrode electrically connected to the TFT and formed so as to correspond to at least the pixel region; a pixel-defining layer formed on the first electrode so as to expose a predetermined region of the first electrode; an intermediate layer connected to the exposed region of the first electrode, including an organic emission layer, and formed to correspond to at least the pixel region; and a second electrode electrically connected to the intermediate layer.
US08487306B2	Photoelectric conversion element, display device, electronic device, and method for manufacturing photoelectric conversion element A photoelectric conversion element includes a first conductive layer over a substrate; a first insulating layer covering the first conductive layer; a first semiconductor layer over the first insulating layer; a second conductive layer formed over the first semiconductor layer; an impurity semiconductor layer over the second semiconductor layer; a second conductive layer over the impurity semiconductor layer; a second insulating layer covering the first semiconductor layer and the second conductive layer; and a light-transmitting third conductive layer over the second insulating layer. A first opening and a second opening are formed in the second insulating layer. In the first opening, the first semiconductor layer is connected to the third conductive layer. In the second opening, the first conductive layer is connected to the third conductive layer. In the first opening, a light-receiving portion surrounded by an electrode formed of the second conductive layer is provided.
US08487304B2	High performance compliant wafer test probe An electrical connection includes a first electrical contact made of electrically conductive material. The first electrical contact is formed with a depression therein. Also included are a deformable pad, having a Young's modulus of less than 1,000,000 psi, which bears on the first contact; and a second electrical contact, made of electrically conductive material, which contacts the first electrical contact and is at least partially received into the depression. The deformable pad at least partially causes at least one lateral force on the first electrical contact, so as to induce the first electrical contact to make an electrical connection with the second electrical contact. An array of such contacts is also contemplated, as is an array of cantilevered contacts, which may or may not have depressions, and which are supported by at least one elastomeric pad, having a Young's modulus of less 72,500 psi.
US08487297B2	Field effect transistor, method for manufacturing the same, and biosensor Disclosed is a carbon nanotube field effect transistor which stably exhibits excellent electrical conduction properties. Also disclosed are a method for manufacturing the carbon nanotube field effect transistor, and a biosensor comprising the carbon nanotube field effect transistor. First of all, an silicon oxide film is formed on a contact region of a silicon substrate by an LOCOS method. Next, an insulating film, which is thinner than the silicon oxide film on the contact region, is formed on a channel region of the silicon substrate. Then, after arranging a carbon nanotube, which forms a channel, on the silicon substrate, the carbon nanotube is covered with a protective film. Finally, a source electrode and a drain electrode are formed, and the source electrode and the drain electrode are electrically connected to the carbon nanotube, respectively. A field effect transistor manufactured by these processes stably exhibits excellent electrical conduction properties since the carbon nanotube, which serves as the channel, is not contaminated.
US08487296B2	Graphene deposition and graphenated substrates Methods, devices, systems and/or articles related to techniques for forming a graphene film on a substrate, and the resulting graphene layers and graphenated substrates are generally disclosed. Some example techniques may be embodied as methods or processes for forming graphene. Some other example techniques may be embodied as devices employed to manipulate, treat, or otherwise process substrates, graphite, graphene and/or graphenated substrates as described herein. Graphene layers and graphenated substrates produced by the various techniques and devices provided herein are also disclosed.
US08487295B2	Semiconductor structures and devices including semiconductor material on a non-glassy bonding layer Methods of fabricating semiconductor structures and devices include bonding a seed structure to a substrate using a glass. The seed structure may comprise a crystal of semiconductor material. Thermal treatment of the seed structure bonded to the substrate using the glass may be utilized to control a strain state within the seed structure. The seed structure may be placed in a state of compressive strain at room temperature. The seed structure bonded to the substrate using the glass may be used for growth of semiconductor material, or, in additional methods, a seed structure may be bonded to a first substrate using a glass, thermally treated to control a strain state within the seed structure and a second substrate may be bonded to an opposite side of the seed structure using a non-glassy material.
US08487286B2	Radiation therapy equipment Radiation therapy equipment includes a multi-divided irradiation collimator leaf plates for setting irradiation field as approximately close to a target region as possible by avoiding backlashes due to a plurality of gears for driving a plurality of leaf plates. The plurality of leaf plates is respectively connected to a plurality of constant force springs that are coaxially supported by a pair of rotation shafts so as to be constantly forced in a closing direction. Each leaf plate is moved in an opening direction by rolling up a wire connected to the leaf plate.
US08487284B2	Prohealing endovascular devices The present invention provides endovascular devices and the methods of making and using the same. The endovascular device is a prohealing endovascular device that comprises a super hydrophilic surface. The super hydrophilic surface is generated by a method comprising a step of irradiating a surface of the endovascular device with a high energy radiation for a period of time to cause the surface to become super hydrophilic.
US08487282B2	Particle beam irradiation apparatus and control method of the particle beam irradiation apparatus A particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan while reducing degradation of a particle beam shape, including a particle beam generation portion; a particle beam emission control portion; a two-dimensional beam scanning portion; a sensor portion including first linear electrodes arranged in parallel in a first direction and second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from outputs of each the first linear and second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose.
US08487280B2	Modulating implantation for improved workpiece splitting A first species is implanted into an entire surface of a workpiece and helium is implanted into this entire surface with a non-uniform dose. The first species may be, for example, hydrogen, helium, or nitrogen. The helium has a higher dose at a portion of a periphery of the workpiece. When the workpiece is split, this split is initiated at the periphery with the higher dose. The non-uniform dose may be formed by altering a scan speed of the workpiece or an ion beam current of the helium. In one instance, the non-uniform dose of the helium is larger than a uniform dose of the hydrogen.
US08487276B2	Scanner photometer methods A scanning photometer and attendant methods are provided. The scanning photometer is generally characterized by first and second fluorophore excitation sources, an objective lens, and a common emission detector for the detection of first and second fluorophore emission originating from the excitation of the fluorophores via passage of excitation energy, via an optical path of the objective lens, from the excitation sources. Excitation energy and emission energy conditioning elements are like-wise provided, operatively interposed before or after the objective lens as the case may be.
US08487275B2	Method and a device for measuring fluorescence lifetime The invention refers to a method for measuring fluorescence lifetime. An excitation light radiation (12a), periodically modulated in a first frequency, is directed to a fluorescent material (20). For the measurement of fluorescence lifetime, the phase difference between the excitation light radiation (12a) and the fluorescent radiation (20a) is measured, the fluorescent radiation being detected by a fluorescent radiation detector (18).According to the invention, a correction signal (16a), periodically modulated in a second frequency, is supplied to a measuring circuit (19), and a phase drift between the emitted correction signal (16a) and the correction signal (16a) processed by the measuring circuit is measured, the phase drift being caused by the measuring circuit. This phase drift is set off against the phase difference between the excitation light radiation (12a) and the fluorescent radiation (20a) which is measured by the fluorescent radiation detector (18), so as to compensate for the measuring error caused by the phase drift of the measuring circuit.
US08487270B2	Particle beam device and method for use in a particle beam device A particle beam device includes a movable carrier element with at least one receiving element for receiving a specimen and in which the receiving element is situated on the carrier element. In various embodiments, the receiving element may be situated removably on the carrier element and/or multiple receiving elements may be situated on the carrier element in such a way that a movement of the carrier element causes a movement of the multiple receiving elements in the same spatial direction or around the same axis. The carrier element may be movable in three spatial directions situated perpendicular to one another and rotatable around a first axis which is parallel to an optical axis of the particle beam device and around a second axis which is situated perpendicular to the optical axis. A method for using the particle beam device in connection with specimen study and preparation is also disclosed.
US08487269B2	Combined radiation therapy and magnetic resonance unit The invention relates to a combined radiation therapy and magnetic resonance unit. For this purpose, in accordance with the invention a combined radiation therapy and magnetic resonance unit is provided comprising a magnetic resonance diagnosis part with an interior, which is limited in radial direction by a main magnet, and a radiation therapy part for the irradiation of an irradiation area within the interior, wherein at least parts of the radiation therapy part, which comprise a beam deflection arrangement, are arranged within the interior.
US08487268B2	Method for the production of multiplayer electrostatic lens array The invention relates to a method for the production of a multilayer electrostatic lens arrangement with at least one lens electrode in general, a method for the production of a phase plate in particular as well as the lens arrangement, the phase plate and a transmission electron microscope with the phase plate.The lens arrangement or the phase plate is produced from a thin self-supporting silicon nitride membrane which is fixed in a macroscopic chip with deposition of further layers.The central bore as well as the aperture opening are milled out by means of an ion beam.
US08487265B2	Imaging detector and method of manufacturing Imaging detectors and methods of manufacturing are provided. One imaging detector includes a first detector layer within a detector module and a second detector layer within the detector module and spaced apart from the first detector layer, wherein the second detector layer has an opening therethrough. The imaging detector also includes a collimator mounted to the detector module, wherein the collimator is one of a single pinhole collimator or a multi-pinhole collimator. Additionally, the second detector layer is mounted within the detector module closer to an opening of the collimator than the first detector layer.
US08487262B2	Radiometric measuring device A radiometric for measuring a physical, measured variable of a fill substance located in a container and for outputting a measurement signal, which corresponds to a measured value of the physical, measured variable. The measuring device has available a single line-pair, via which energy supply of the total measuring device occurs, and via which transmission of the measurement signal occurs. The measuring device includes: a radioactive radiator, which, during operation, sends radioactive radiation through the container; a detector having a scintillator and a photomultiplier and serving for detecting, and for converting into an electrical output signal, radiation intensity penetrating through the container dependent on the physical, measured variable to be measured; a measuring device electronics, which serves, on the basis of the electrical output signal of the detector, for producing the measurement signal and for making such available via the line-pair; an energy storer supplied via the line-pair; a controller, which, as a function of energy available via the line-pair and the energy storer, triggers measuring phases, during which the measuring device measures the physical, measured variable, and which places the photomultiplier in operation exclusively during the measuring phases, wherein high voltages required for operating the photomultiplier are produced during the measuring phases by means of a high voltage cascade.
US08487260B2	Sensor The invention provides a sensor including a first sensor element formed in a first substrate and at least one optical element formed in a second substrate, the first and second substrates being configured relative to one another such that the second substrate forms a cap over the first sensor element, the at least one optical element being configured to guide incident radiation on the cap to the first sensor element. The sensor also includes a reference sensor element whose output can be used to reference the output of the first sensor element.
US08487254B2	Network centric system and method for active thermal stealth or deception A system and method for active thermal stealth or deception, the system including at least two objects, each having at least one active plate and a processing module coupled to the active plate for activating the plate to provide a desired thermal signature to the object, and a remotely located central control unit for external actuation of the processing modules in each object.
US08487251B2	Method for controlling charging of sample and scanning electron microscope An object of the present invention is to provide a scanning electron microscope aiming at making it possible to control the quantity of electrons generated by collision of electrons emitted from a sample with other members, and a sample charging control method using the control of electron quantity. To achieve the object, a scanning electron microscope including a plurality of apertures through which an electron beam can pass and a mechanism for switching the apertures for the electron beam, and a method for controlling sample charging by switching the apertures are proposed. The plurality of apertures are at least two apertures. Portions respectively having different secondary electron emission efficiencies are provided on peripheral portions of the at least two apertures on a side opposed to the sample. The quantity of electrons generated by collision of electrons emitted from the sample can be controlled by switching the apertures.
US08487249B2	Auxiliary frequency parametric excitation of quadrupole mass spectrometers The apparatus introduces a second adjustable resonant point in a QMS at a frequency that is close to a multiple of the fundamental frequency by adjusting driving point impedance characteristics of the QMS. The apparatus measures the first and second resonant point of the QMS to account for changes in the operational characteristics of the QMS.
US08487248B2	Method and apparatus for frequency-based axial ejection of ions An ion trap mass analyzer is disclosed comprising a segmented rod set. Ions are trapped radially within the mass analyzer by a radial pseudo-potential well. The ions are also confined axially within a quadratic axial potential well. An AC voltage or potential is applied to the electrodes comprising the ion trap mass analyzer in order to excite parametrically ions within the ion trap.
US08487245B2	Direct atmospheric pressure sample analyzing system A system, method and apparatus for injecting reactive species and ions from an ambient plasma ionization source into an atmospheric pressure ion mobility spectrometer.
US08487243B2	Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry The invention provides a method and apparatus for trapping, releasing and/or separating sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current comprises cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or Anion ion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range. The invention when interfaced to an Atmospheric Pressure Ion Source, that may include Electrospray Ionization, with mass spectrometric analysis enables independent control of the on-line sample separation process and the Atmospheric Pressure Ion Source or Electrospray ionization processes.
US08487234B2	Electron emission device having an electrodes' arrangement and an antenna circuit with operational frequency in THz-range An electric device operable with a THz-range frequency of the device output is presented. The device comprises a photocathode installed in either one of a diode, triode and tetrode configuration, and is exposed to illumination. In some embodiments of the invention, the device is configured as a diode and photomixing is used for illumination of the photocathode with light in the THz range, the diode converting this input light signal into an electrical output in the THz range, which operates a signal transmitter/receiver. In some other embodiments of the invention, the device is configured as a triode or tetrode, where the electrodes have small dimensions (about 1 micron or less) and are spaced from one another a distance not exceeding 1 micron. The photocathode is kept under certain illumination, and electrical signal applied to one of the electrodes results in the THz output at one of the other electrodes.
US08487230B2	Intelligent solar energy collection system with a dedicated control device A solar energy collection system comprises a plurality of solar panels and a control device. The panel further comprises a plurality of solar modules, a supporting, pivoting and tilting mechanism, a controller and a short range communication unit. The control device comprises an orientation detector for determining the optimized orientation of a panel towards the sun for receiving maximum sun radiation. The control device further comprises a communication unit. The optimized orientation determined by the control device may be transmitted to the solar panels through an ad hoc communication network.
US08487229B2	Portable, durable, integrated solar power generation device A solar power generation device including a base, a tracking system mounted to the base, a solar collector mounted to the tracking system configured to open as the solar power generation device transitions to an active state and to close as the solar power generation device transitions to an inactive state, a light sensing system dynamically mounted about the base and configured to adjust the tracking system based upon the position of a light producing element, and a plurality of focusing elements mounted to the base and positioned around the light sensing system such that any light reflected by the focusing elements is directed to the solar collector. The device may further include an electricity management and conditioning system contained in the base that includes a short term storage system, a long term storage system, a data acquisition system, and a data and electricity transmission interface.
US08487227B2	Speed-adaptive deployable boat-tailing cone for munitions for range extension A base cone for a projectile including: a cone member being movable between a retracted position and an extended deployed position, the deployed position being longer in an axial direction than the refracted position; a member adapted to connect the cone member to a trailing portion of the projectile; and a release mechanism for releasing the cone member from the refracted position to the extended deployed position.
US08487223B2	Microwave reactor having a slotted array waveguide A system for heating materials, such as wood products, is provided. The system may include waveguide having one or more slots along a longitudinal axis of the waveguide. The slots may be slanted at an angle with respect to the longitudinal axis and spaced at an interval of about one half of a wavelength along the longitudinal axis. The system may further include windows covering the slots. The windows may serve as a barrier. Moreover, the windows may allow electromagnetic energy to be transferred from the waveguide to the material being heated. The waveguide and window may be contained in a microwave reactor to heat materials, such as wood products.
US08487217B2	Method of pulse welding and contact tip therefor A contact tip for a welding gun having a central passage for a welding wire moving in a given direction toward a workpiece and receiving a welding signal by contact of the wire with the tip. The passage has an innermost end, an outermost exit end and a length of at least 1.5 inches and an opening in the contact tip intersects the passage so a pressure block slidably mounted in the opening is biased toward the wire by a spring around the contact tip urging the block against the wire. This tip is dimensioned and constructed to perform pulse welding by a relatively ductile aluminum wire.
US08487216B2	Remotely controlled welding machine The present invention is directed to a remotely controlled welding machine. A remote control uses the welding circuit to transfer information to a welding power source. The information to be communicated to the power source includes welding power source output command information (amperage/voltage control), welding circuit on/off information (power source output contactor control), and power source mode control (constant voltage/constant current). A transmitter transmits the desired welding operational parameters to a receiver disposed in the power source. The transmitter is constructed to use only a small amount of power which, preferably, is supplied by one or two low voltage replaceable and/or rechargeable batteries. Additionally, an open circuit voltage is not created between the power source and an electrode holder when an arc is not present.
US08487207B2	Apparatus and method for cutting hollow cylindrical workpiece A rotatable workpiece holder for holding a hollow cylindrical workpiece thereon functions as a chiller for cooling the hollow cylindrical workpiece. A coolant, e.g., water, is supplied to the hollow cylindrical workpiece through second coolant passages and branch passageways defined in the workpiece holder, thereby cooling the hollow cylindrical workpiece. The coolant forms a film in a clearance between the outer surface of an annular side wall of the workpiece holder and the inner circumferential surface of the hollow cylindrical workpiece.
US08487204B2	Single pole or multi-pole double break switching devices The present invention relates to a switching device, in particular an automatic switch, a disconnector or a contactor, with high dependability, for use preferably in low voltage electrical systems. In particular the invention relates to a single-pole or multi-pole double break switching device for low voltage systems comprising, for each pole, at least a first pair of contacts and at least a second pair of contacts. Each pair comprises a stationary contact and a movable contact which can be reciprocally coupled/decoupled at the level of a first breaking cavity and a second breaking cavity respectively. Said cavities are defined inside a casing which comprises a first surface with respect to which an internally hollow portion protrudes, said internally hollow being integrally made with at least one portion of the casing. The hollow portion defines, for each pole, one or more discharge channels each of which has a first section communicating with the corresponding first breaking cavity and a second section communicating with the environment outside the casing to permit the discharge of gas from the inside of the first breaking cavity.
US08487203B2	Disconnecting switch with earthing switch Operating shaft 4 allows disconnecting switch-side and earthing switch-side moving contacts 7a and 7b to linearly reciprocate with the rotation of operating shaft 4. Operating shaft 4 has two-hole lever 5 allow an arc motion. Each one end of two curved links 6a and 6b is connected to two-hole lever 5 and the other end of two curved links 6a and 6b is respectively connected to the disconnecting switch-side moving contact or the earthing switch-side moving contact. When the two connecting points are axisymmetric with respect to the bisector, both the disconnecting switch and the earthing switch are in an open state; when two-hole lever 5 moves at a predetermined angle to the disconnecting switch-side, the disconnecting switch is in a closed state; and when two-hole lever 5 moves at a predetermined angle to the earthing switch-side, the earthing switch is in a closed state.
US08487201B2	Contact element and a contact arrangement A contact element for making an electric contact to a contact member for enabling an electric current to flow between the contact element and the contact member. The contact element includes a body having at least one contact surface thereof coated with a contact layer to be applied against the contact member. The contact layer includes a nanocomposite film having a matrix and crystallites of nano-size embedded therein. Portions of the matrix separating adjacent the crystallites of the nanocomposite film have a thickness providing the matrix and hence the film with an electrical conductivity determined by a substantially two-dimensional character of the matrix.
US08487198B2	Capacitive touch control device and method thereof Disclosed are a capacitive touch control device and a method thereof. A top face of a substrate is provided with first and second electrode groups, which each include a plurality of strip-like electrodes spaced from each other by a preset distance. The electrodes of the first and second electrode groups are respectively connected by first and second group scanning lines to a scanning circuit. When the first group scanning lines drive the electrodes of the first electrode group, the second group scanning lines carry out scanning operation on the electrodes of the second electrode group, and when the second group scanning lines drive the electrodes of the second electrode group, the first group scanning lines carry out scanning operation on the electrodes of the first electrode group. And, a touch location can thus be determined by using a microprocessor.
US08487194B2	Circuit board including an embedded component The document describes a circuit board and an electronic module, including a conductor-pattern layer, an insulating-material layer supporting the conductor-pattern layer, and at least one component inside the insulating-material layer. The component has a plurality of contact areas and the circuit board or electronic module includes contact elements between the conductor-pattern layer and contact areas for electrically connecting the conductor-pattern layer and the at least one component such that at least two of the contact elements are in direct contact with a common contact area.
US08487193B2	Conductive plate A conductive plate includes a substrate, an adhesive, and a conductive layer attached to the substrate through the adhesive. The conductive layer includes a plurality of conductive films, each of which includes a plurality of nanounits.
US08487191B2	Flexible laminate and flexible electronic circuit board formed by using the same An adhesive-free flexible laminate formed from a polyimide film in which at least one surface has been plasma treated, a tie-coat layer formed on the surface of the plasma-treated polyimide film, a metal seed layer made of either copper or copper alloy and which is formed on the tie-coat layer, and a metal conductive layer made of either copper or copper alloy and which is formed on the metal seed layer, wherein the atomic percent of Cu inclusion in the tie-coat layer is 0.5 at % or less. Consequently, provided is a flexible laminate capable of effectively inhibiting the deterioration of the peel strength upon producing a flexible laminate (in particular a two-layer metalizing laminate).
US08487188B2	Grommet A grommet includes a small diameter tubular section and a large diameter tubular section contiguous with the small diameter tubular section. The large diameter tubular section is provided on the outer peripheral surface with a plurality of projecting portions that extend from a connecting part between both of the sections to a side wall of vehicle body engagement annular recess in an axial direction of the large diameter tubular section and are separated from one another in a peripheral direction of the large diameter tubular section. Each of the projecting portions includes an increasing diameter directing slant portion that extends from the proximal end point through the contact point to the bending point in parallel to the outer peripheral surface of the large diameter tubular section, and a decreasing diameter directing slant portion that extends from the bending point to the distal end point and inclines in a reversed slant direction.
US08487187B2	Solid core glass bead seal with stiffening rib A hermetic feed-through includes a housing body defining a hollow space, a plurality of conductive pins and a seal structure. The plurality of conductive pins extend through the hollow space. The seal structure is provided in the hollow space and includes a single-piece glass component. The single-piece glass component hermetically seals at least two conductive pins to the housing body and electrically insulates the at least two conductive pins from the housing body.
US08487184B2	Communication cable A signal transmission cable including a center core (10) of twisted pairs (10B) of insulated wires (10A). Then, a first layer of foamed polyolefin tape (11), which protects the core insulation from erosion by the shield materials, and distances them from the core so that the shield materials are more effective in their shielding. This distancing has the effect of allowing the continuous metal shielding layer to be thinner without losing shielding effectiveness. Then, a second layer of braided wire (12), angled at 45 degrees from the axis of the core. Third, a layer formed of a three-sub-layer laminate (13), The inner sub-layer is metallic aluminum (13A), attached to a middle sub-layer of polyester tape (13B). The outer surface of the polyester tape (13B) is metallized, that is, the outer surface of the polyester tape is impregnated with a very thin sublayer of aluminum (13C). Fourth, a jacket (14).
US08487183B2	Contact unit and method for producing a contact unit The invention relates to a contact unit and particularly a solder pin, and a method for producing a contact unit, comprising a body having a metal core and a tin layer surrounding the metal core. The tin layer is thereby designed as a duplex layer, and comprises a radially inner layer overlay of matte tin and a radially outer layer overlay of glossy tin.
US08487178B2	Alkaline earth filled nickel skutterudite antimonide thermoelectrics A thermoelectric material including a body centered cubic filled skutterudite having the formula AxFeyNizSb12, where A is an alkaline earth element, x is no more than approximately 1.0, and the sum of y and z is approximately equal to 4.0. The alkaline earth element includes guest atoms selected from the group consisting of Be, Mb, Ca, Sr, Ba, Ra and combinations thereof. The filled skutterudite is shown to have properties suitable for a wide variety of thermoelectric applications.
US08487177B2	Integrated thermoelectric honeycomb core and method The disclosure provides a thermoelectric composite sandwich structure with an integrated honeycomb core and method for making. The thermoelectric composite sandwich structure comprises two prepreg composite face sheets and an integrated honeycomb core assembled between the face sheets. The honeycomb core comprises a plurality of core elements bonded together with a core adhesive. Each core element has a first side substantially coated with a negative Seebeck coefficient conductive material having a plurality of first spaced gaps, and each core element further has a second side substantially coated with a positive Seebeck coefficient conductive material having a plurality of second spaced gaps. The honeycomb core further comprises a plurality of electrical connections for connecting in series the first side to the second side. A temperature gradient across the honeycomb core generates power.
US08487176B1	Music and sound that varies from one playback to another playback A method and apparatus for the creation and playback of music and/or sound, so that sound sequences are generated that vary from one playback to another playback. In one embodiment, during composition creation, artist(s) may define how the composition may vary from playback to playback using visually interactive display(s). The artist's definition may be embedded into a composition dataset. During playback, a composition data set may be processed by a playback device and/or a playback program, so that each time the composition is played-back a unique version may be generated. Variability during playback may include: the variable selection of alternative sound segment(s); variable editing of sound segment(s) during playback processing; variable placement of sound segment(s) during playback processing; the spawning of group(s) of alternative sound segments from initiating sound segment(s); and the combining and/or mixing of alternative sound segments in one or more sound channels. MIDI-like variable compositions and the variable use of sound segments comprised of a timed sequence of MIDI-like commands are also disclosed.
US08487175B2	Music analysis apparatus In a musical analysis apparatus, a spectrum acquirer acquires a spectrum for each frame of an audio signal representing a piece of music. A beat specifier specifies a sequence of beats of the audio signal. A feature amount extractor divides an interval between the beats into a plurality of analysis periods such that one analysis period contains a plurality of frames, and separates the spectrum of the frames contained in one analysis period into a plurality of analysis bands so as to set a plurality of analysis units in one analysis period in correspondence with the plurality of the analysis bands, such that one analysis unit contains components of the spectrum belonging to the corresponding analysis band. The feature amount extractor further calculates a feature value of each analysis unit based on the components of the spectrum contained in each analysis unit, thereby generating a rhythmic feature amount that is an array of the feature values calculated for the analysis units and that features a rhythm of the piece of music.
US08487174B2	Method of instructing an audience to create spontaneous music A method of instructing an audience to spontaneously create music at an entertainment event is disclosed. The method comprises providing noisemakers to groups of participants, the noisemakers being distinguishable between the plurality of types and each noisemaker sounding a single note. A dynamic display comprising a screen and a notice period shows instructions to the participants. The instructions direct the participants to sound their respective noisemakers at different times. The combined sound from the various noisemakers thereby produces a musical score.
US08487173B2	Methods for online collaborative music composition Systems and methods for creating and editing collaborative music compositions via a computer network, including remote uploading tracks by musicians, and for creating and joining a band, wherein the system and methods provide for at least one musician to join a virtual group of at least one other musician for the purpose of virtual collaborative creating and/or editing music tracks remotely, via an online network and interactive website therefor.
US08487171B2	Foot machine for a bass drum of a drum kit The foot machine according to the invention for a bass drum of a drum kit basically comprises a shaft mounted rotatably in a frame, a beater supported on the shaft, and a pedal connected to the beater, operation of the pedal bringing about an excursion of the beater. Also provided are permanent magnet restoring means which bring the displaced beater back into a resting position and which are formed by at least one inner and at least one outer permanent magnet arrangement arranged concentrically around the shaft.
US08487170B2	Percussion instrument The present invention relates to a percussion instrument of the type consisting of a box composed of four walls (1) forming the outline, on which a top (2) rests, the lateral end walls (3-4) having a rectangular profile, the front (5) and rear (6) faces having a convex profile (7) in their lower part while in their upper part on which the top rests they follow a line which is firstly rectilinear (8), then continued by a concave part (9), which is itself continued by a rectilinear or very slightly convex part (10), such that the box is divided into three zones: a deep zone (8) for producing bass sounds, continued by a shallower median part (9) for producing middle register sounds, said median part itself being continued in such a way as to form a chamber (10) which is slightly deeper than the median part for producing high pitched sounds, the chamber (10) producing the high pitched sounds being provided with a snare (17) lying against the top.
US08487168B1	Method for manufacturing coated strings including glow in the dark strings Method for forming a musical instrument string and string formed thereby in which a core wire having a coating thereon is formed and a wrap wire is wound around the coated core wire. Musical instrument string that glows in the dark and may be formed by providing a first wire that will serve as a core wire of the string, providing a second wire that will serve as a wrap wire of the string, applying a thermoplastic or thermosetting luminescent polymer to the second wire, e.g., by electrostatic application, and then curing the second wire, controlling the curing conditions under which the second wire is cured to ensure the second wire, after curing is windable, and then winding the cured, second wire around the first wire to provide the string that glows in the dark.
US08487156B2	Hygiene articles containing nanofibers The present invention is directed to hygiene articles comprising nanofibers. The hygiene articles include diapers, training pants, adult incontinence pads, catamenials products such as feminine care pads and pantiliners, tampons, personal cleansing articles, personal care articles, and personal care wipes including baby wipes, facial wipes, body wipes, and feminine wipes. The nanofiber webs can be used as a barrier, wipe, absorbent material, and other uses. Particularly, the nanofiber web is used in a diaper as a barrier-on-core, outercover, and/or leg cuff. It may also be used as a wipe for reducing the gradient of liquid, controlled delivery of materials, and other uses. The nanofibers, having a diameter of less than 1 micron, must comprise a significant number of the fibers in one layer of the web contained by the hygiene article. The nanofibers are produced from a melt film fibrillation process. The process generally includes the steps of providing a polymeric melt, utilizing a central fluid stream to form an elongated hollow polymeric film tube, and using this and/or other fluid streams to form multiple nanofibers from the hollow tube.
US08487155B2	Removal of light fluoroalkanes from hydrocarbon streams The removal of fluoroalkanes from fluoroalkane-containing hydrocarbon streams, preferably C3 to C5 hydrocarbon streams. The fluoroalkane-containing hydrocarbon stream is contacted with an adsorbent containing a strong acid function, preferably a silica gel or a strong cation ion-exchange resin having sulfonic acid functionality.
US08487154B2	Market driven alkylation or oligomerization process A process comprising adjusting a level of conjunct polymers in an ionic liquid catalyst between a low level that favors production of C5+ products boiling at 137.8° C. or below and a higher level that favors production of both C5+ products boiling at 137.8° C. or below and C5+ products boiling above 137.8° C.; wherein the adjusting is done in response to market demand. A process unit, comprising a reactor that operates with an ionic liquid catalyst comprising a low level or a higher level of conjunct polymers, and the alkylation reactor is switched between operating with the low and the higher levels in response to market demand. A process unit, comprising a reactor that operates in an alkylate mode and a distillate mode, and a catalyst regenerator that operates with varying severity to adjust the level of conjunct polymers in response to demand for gasoline or distillate.
US08487153B2	Selective olefin dimerization with supported metal complexes activated by alkylaluminum compounds or ionic liquids Methods for dimerizing alpha-olefins utilizing immobilized buffered catalysts wherein a buffered ionic liquid is mixed with an organometallic complex of the formula: where X is a halogen, n=2 or 3, M=Ti, V, Cr, Mn, Fe, Co and Ni and R1, R2, R3 and R4 are selected from the group consisting of hydrogen, alkyl, aryl, alkenyl, alkynyl, alkyloxy, substituted aryl, and X are provided. A method for dimerizing alpha-olefins utilizing the immobilized buffered catalysts and a co-catalyst is also provided.
US08487152B2	Process for converting natural gas to aromatics with electrochemical removal of hydrogen to generate electrical power and obtain hydrogen The present invention relates to a process for converting aliphatic hydrocarbons having 1 to 4 carbon atoms to aromatic hydrocarbons, comprising the steps of: a) converting a reactant stream E which comprises at least one aliphatic hydrocarbon having 1 to 4 carbon atoms in the presence of a catalyst under nonoxidative conditions to a product stream P comprising aromatic hydrocarbons and hydrogen, and b) electrochemically removing at least some of the hydrogen formed in the conversion from the product stream P by means of a gas-tight membrane-electrode assembly which has at least one selectively proton-conducting membrane and, on each side of the membrane, at least one electrode catalyst, at least some of the hydrogen being oxidized to protons over the anode catalyst on the retentate side of the membrane, and the protons, after passing through the membrane, on the permeate side over the cathode catalyst, are partly, in b1) reduced to hydrogen with application of a voltage, and partly, in b2) reacted with oxygen to give water to generate electrical power, the oxygen originating from an oxygen-comprising stream O which is contacted with the permeate side of the membrane.
US08487150B2	Process for hydrogenating butadiyne In the process for hydrogenating butadiyne over a catalyst which comprises at least one platinum group metal on an inorganic metal oxide as a support, the hydrogenation is performed at a pressure in the range from 1 to 40 bar and a temperature in the range from 0 to 100° C., and from 0.05 to 5% by weight, based on the overall catalyst, of platinum group metal is present on the support.
US08487145B2	Catalysts and process to manufacture 2,3,3,3-tetrafluoropropene Disclosed is a process for the manufacture of 2,3,3,3-tetrafluoropropene comprising: (a) contacting 1,1,1,2,3-pentafluoropropane with a catalyst comprised of chromium (III) oxide having a surface area of at least 150 m2/g and having an alkali metal loading of at least 7 milligrams of alkali metal per 100 square meters of catalyst surface area, to produce a product mixture comprising 2,3,3,3-tetrafluoropropene and hydrogen fluoride; and (b) recovering said 2,3,3,3-tetrafluoropropene from the product mixture produced in (a).
US08487142B2	Process for producing small molecular weight organic compounds from carbonaceous material The present invention discloses a process for producing small molecular weight organic compounds from carbonaceous material comprising a step of contacting the carbonaceous material with carbon monoxide (CO) and steam in presence of a shift catalyst at a predetermined temperature and pressure.
US08487139B2	Curcumin and tetrahydrocurcumin derivatives The invention relates to novel curcumin and tetrahydrocurcumin derivatives, which have been modified at one phenolic group to incorporate more-reactive groups. The curcumin and tetrahydrocurcumin derivatives are in the form of monomers, dimmers, and polymers.
US08487136B2	Method for producing norbornene derivative A method for selectively producing a monoaryl norbornene derivative represented by a formula (5) involves having a norbornadiene derivative represented by a formula (3) and a bromine compound represented by a formula (4) react with each other in the presence of a reducing agent, palladium and at least one selected from phosphorus compounds represented by the formulas (1) and (2), whereby the norbornene derivative represented by formula (5) having a monoaryl substituent is an exo configuration.
US08487131B2	Optically pure apogossypol derivative as pan-active inhibitor of anti-apoptotic B-cell lymphoma/leukemia-2 (BCL-2) A compound of Formula I: or a pharmaceutically acceptable salt thereof is disclosed. In addition, pharmaceutical compositions thereof, methods for preparing and methods for using this compound or composition for treating a variety of diseases, including cancer and inflammation are also provided.
US08487128B2	Protection of normal cells The invention provides compositions comprising sulindac, R-epimer sulindac, S-epimer sulindac, derivatives, metabolites, and structural analogs thereof which protect normal cells against damage caused by solar rays, oxidative damage, environmental factors, diseases and organisms.
US08487127B2	Process for preparing isocyanates in the gas phase The invention relates to a process for preparing isocyanates by reacting the corresponding amines with phosgene in the gas phase, in the presence or absence of an inert medium, which comprises the following steps: (a) vaporization of the amine in a vaporizer, (b) superheating of the amine, (c) mixing of the gaseous amine with the phosgene and introduction into a reaction zone, (d) reaction of amine and phosgene to give isocyanate in the reaction zone, with a reaction mixture comprising isocyanate and hydrogen chloride being formed, (e) cooling of the reaction mixture comprising isocyanate and hydrogen chloride, wherein the vaporizer comprises a vessel in which tubes through which a heating medium flows are comprised, where number and diameter of the tubes are designed so that the tubes have a specific heat transfer area based on the volume through which the amine flows of at least 300 m2/m3.
US08487123B2	Process for initiating a highly selective ethylene oxide catalyst A start-up process for epoxidation of ethylene is provided. The process includes initiating an epoxidation reaction by reacting a feed gas composition in the presence of an epoxidation catalyst at a first temperature of about 180° C. to about 210° C. The first temperature is increased to a second temperature of about 230° C. to about 290° C., over a time period of about 6 hours to about 50 hours, while simultaneously adding a sufficient concentration of moderator so that the amount of moderator adsorbed on the catalyst after achieving the second temperature is from about 10 to about 50 g/m3 of catalyst. The second temperature is maintained for about 50 hours to about 350 hours, while regulating the feed gas composition to contain about 0.5% to about 25% CO2. The second temperature is decreased to a third temperature, while simultaneously increasing moderator concentration to a level greater than the sufficient concentration.
US08487114B2	Fused thiophenes and methods for making and using same Disclosed are compounds having one of the following formulae (11), (12), wherein X is an aromatic nucleophilic substitution leaving group; R1 is hydrogen, an alkyl group, or an aryl group; and Q1 is a carboxyl protecting group or an aldehyde protecting group. Also disclosed are fused thiophenes that can be prepared using these compounds, as well as stannylthio-containing thiophene, thienothiophene, and dithienothiophene compounds that can be used to prepare fused thiophenes. Methods for making and using the aforementioned compounds, fused thiophenes, and stannylthio-containing thiophene, thienothiophene, and dithienothiophene compounds are also disclosed.
US08487113B2	Method for the preparation of tizanidine hydrochloride The invention deals with a preparation method of salts of 5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole (tizanidine) of formula I, especially tizanidine hydrochloride, comprising preparation of a salt of tizanidine of formula I and a carboxylic acid as an intermediate, from which, after acidification with hydrogen chloride, tizanidine hydrochloride is obtained in a high yield and purity.
US08487101B2	Thieno-pyridine derivatives as MEK inhibitors A series of thieno[2,3-b]pyridine derivatives which are substituted in the 2-position by a substituted anilino moiety, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions.
US08487097B2	Reference standard for characterization of rosuvastatin Provided are rosuvastatin degradation products and their use as a reference standard (including reference marker) for analysis of rosuvastatin.
US08487094B2	Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1 Disclosed are syntheses of 11β-HSD1 inhibitors and corresponding intermediates that are promising for the treatment of a variety of disease states including diabetes, metabolic syndrome, obesity, glucose intolerance, insulin resistance, hyperglycemia, hypertension, hypertension-related cardiovascular disorders, hyperlipidemia, deleterious gluco-corticoid effects on neuronal function (e.g. cognitive impairment, dementia, and/or depression), elevated intra-ocular pressure, various forms of bone disease (e.g., osteoporosis), tuberculosis, leprosy (Hansen's disease), psoriasis, and impaired wound healing (e.g., in patients that exhibit impaired glucose tolerance and/or type 2 diabetes).
US08487092B2	Pyrrolobenzodiazepines The invention relates to certain pyrrolobenzodiazepines (PBDs), and in particular pyrrolobenzodiazepine dimers bearing C2 substitutions, including compounds of formula (T): wherein: R2 is CHR2A, and R2A is independently selected from H, R, CO2R, COR, CHO, CO2H, and halo; R6 and R9 are independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR′, NO2, Me3Sn and halo; R7 is independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR′, NO2, Me3Sn and halo; R8 is independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR′, NO2, Me3Sn and halo; R is independently selected from optionally substituted C1-12 alkyl, C3-20 heterocyclyl and C5-20 aryl groups; or the compound is a dimer with each monomer being of formula (M), where the R7 groups or R8 groups of each monomer form together a dimer bridge having the formula —X—R″—X— linking the monomers; wherein R″ is a C3-12 alkylene group, which chain may be interrupted by one or more heteroatoms, e.g. O, S, N(H), and/or aromatic rings, e.g. benzene or pyridine; and each X is independently selected from O, S, or N(H); or any pair of adjacent groups from R6 to R9 together form a group —O—(CH2)p—O—, where p is 1 or 2, and salts and solvates thereof, and their use as intermediates for the preparation of other PBD compounds.
US08487090B2	Water solution of 20(R)-ginsenoside Rg3 pharmaceutical composition and process thereof A preparation of a kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution containing ginsenoside Rg3 0.5˜10 mg/ml: add 0.1-5% of ginsenoside solution to 0.1˜30% of adjuvant A, B{circle around (1)}{circle around (2)}{circle around (5)} at the temperature of 40˜100° C., the ratio of these two is 1:1˜300, add water after the solvent is recycled under reduced pressure; another kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution contains 0.1˜2 mg/ml of 20(R) of the ginsenoside Rg3, the preparation: add 0.1˜5% of ginsenoside solution to 20˜65% of adjuvant B{circle around (3)}{circle around (4)} at the temperature of 60˜100° C., main material to adjuvant B=1:100˜400, add water after the solvent is recycled under reduced pressure. The above 20(R) ginsenoside Rg3 composition aqueous solution and the powder after lyophilizaton can be used to prepare injectable, oral administration and external use, and the bioactivity of these preparations is high, and with the actions of anti cancer, efficacy potentiation and toxicity attenuation effects of the combined chemical or radiation therapy of tumor, enhancement of human immune functions, improvement of human memory, anti fatigue, and detumescence, pain relieving.
US08487087B2	Model animal in which state of disease condition is observable in real time, gene construct for achieving the same and use of the same Provided is a technique for observing in real time the state of a disease condition in a tissue of an animal or the state of a functionally adverse condition which is a prelude to the disease condition without injuring the animal. This can be achieved by the use of a gene construct having a reporter gene integrated under the control of a hypoxia responsible promoter an ODD domain (oxygen dependent degradation domain) integrated upstream to the reporter gene.
US08487085B2	Analyzing messenger RNA and micro RNA in the same reaction mixture The present teachings provide methods, compositions, and kits for performing primer extension reactions on at least two target polynucleotides in the same reaction mixture. In some embodiments, a reverse transcription reaction is performed on a first target polynucleotide with a hot start primer comprising a self-complementary stem and a loop, and extension products form at high temperatures but extension products form less so at low temperatures since the self-complementary stem of the hot start primer prevents hybridization of the target specific region to the target. However, non-hot start primers with free target specific regions can hybridize to their corresponding targets at the low temperature and extension can happen at the low temperature.
US08487082B2	Synthetic scFv analogue to the 6313/G2 (anti angiotensin II type 1 receptor) monoclonal antibody variable regions The present invention provides a specific binding molecule which specifically binds to a peptide having the amino acid sequence of EDGIKRIQDD and comprises a polypeptide having an immunoglobulin VL domain linked to an immunoglobulin VH domain in which the VL domain comprises Complementarity Determining Regions (CDRs) VLCDR1, VLCDR2 and VLCDR3, and in which the VH domain comprises Complementarity Determining Regions (CDRs) VHCDR1, VHCDR2, VHCDR3, each having a respective amino acid sequence as follows in which VHCDR1 is GYSFTGYNMN VHCDR2 is NIDPYYGGTTYNQKFKG VHCDR3 is EVDY VLCDR1 is RASKSVSTSTSGYSYMH VLCDR2 is LVSNLES VLCDR3 is QHIRELTRSEG or an amino acid sequence at least 70% identical thereto.
US08487080B2	Fluorine-labeled compounds Methods for introducing fluorine atom onto a polypeptide are provided. Also provided are linkers, bioconjugates, and bifunctional compound agents made using the methods, linkers, and bioconjugates. The methods comprise: (i) providing a linker comprising a thiol-reactive terminus and an aldehyde-reactive terminus; (ii) reacting the thiol-reactive terminus of the linker with a polypeptide comprising at least one thiol group or a reactive derivative thereof; and (iii) subsequently reacting the aldehyde-reactive terminus of the linker with a fluorine-substituted aldehyde.
US08487076B1	HLA-binding peptide, and DNA fragment and recombinant vector coding for said HLA-binding peptide There is provided an HLA-binding peptide binding to a HLA-A type molecule, the HLA-binding peptide comprising at least one type of amino acid sequence selected from the group consisting of SEQ ID NOS: 1 to 80, and consisting of not less than 8 and not more than 11 amino acid residues. All of these amino acid sequences herein mentioned are the predicted amino acid sequences binding to a human HLA-A type molecule with the prediction program using the certain active learning method.
US08487073B2	Melanocortin receptor-specific peptides for treatment of sexual dysfunction A melanocortin receptor agonist cyclic peptide of the formula where R, x and y are as defined in the specification, compositions and formulations including the peptide of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes, including sexual dysfunction such as male erectile dysfunction and female sexual dysfunction.
US08487070B2	Sulfonated poly(arylene ether) having crosslinkable moiety combined in chain of polymer, sulfonated poly(arylene ether) having crosslinkable moieties combined in polymer and at polymer end group, and polymer electrolyte membrane using sulfonated poly(arylene ether) A sulfonated poly(arylene ether) copolymer that has a crosslinking structure in a chain of a polymer, a sulfonated poly(arylene ether) copolymer that has a crosslinking structure in and at an end of a chain of a polymer, and a polymer electrolyte film that is formed by using them are disclosed. According to the polycondensation reaction of the sulfonated dihydroxy monomer (HO—SAr1-OH), the none sulfonated dihydroxy monomer (HO—Ar—OH), the crosslinkable dihalide monomer (X—CM-X) and the none sulfonated dihalide monomer (X—Ar—X), the poly(arylene ether) copolymer in which the sulfonic acid is included is synthesized. The formed poly(arylene ether) copolymer has the crosslinkable structure in the chain of the polymer. In addition, by carrying out the polycondensation reaction in respects to the crosslinkable monohydroxy monomer or the crosslinkable monohalide monomer, the crosslinking can be formed at the end of the polymer. Through this, the thermal stability, the mechanical stability, the chemical stability, the film formation ability and the like is the same as or better than those of the Nafion film that is currently commercialized and is used as the polymer electrolyte film, and the proton conductivity and the cell performance are excessively improved. In addition, even though it is exposed to the moisture over a long period of time, since there is no change in the property of the electrolyte film, the dimensional stability is high.
US08487067B2	Polycarbonate resin and transparent film formed therefrom A polycarbonate resin which is excellent in terms of optical properties, hue, thermal stability, and mechanical properties and a transparent film formed from the resin are provided. The invention relates to a polycarbonate resin which has a glass transition temperature of 110-150° C. and a reduced viscosity, as measured at 20° C. with respect to the methylene chloride solution having a concentration of 0.6 g/dL, of 0.30-0.46, and which, when being molded, gives a film wherein the ratio of the retardation thereof measured at a wavelength of 450 nm (Re450) to the retardation thereof measured at a wavelength of 550 nm (Re550) is 0.50-0.93.
US08487059B2	Synthesis of dendritic polyolefins by metathesis insertion polymerization A one step process for making a dendritic hydrocarbon polymer, e.g., dendritic polyolefin, by metathesis insertion polymerization. The process comprises polymerizing an amount of one or more cyclic olefins and one or more multi-functional (meth)acrylates in the presence of a metathesis catalyst and under conditions sufficient to produce the dendritic hydrocarbon polymer. The one or more multi-functional (meth)acrylates have a functionality of 3 or higher. The dendritic hydrocarbon polymer can be hydrogenated to produce a substantially saturated dendritic hydrocarbon polymer. The hydrogenation can take place in the same reaction vessel as the polymerization, i.e., one pot process.
US08487045B2	Pressure pipes and polyolefin composition for the manufacture thereof Articles, particularly pressure pipes, having high strength as well as high stiffness and very good impact resistance even at low temperatures can be obtained by using a heterophasic polyolefin composition comprising (percent by weight) 70-90% of a random copolymer of propylene with 0.5-6% of 1-hexene, and 10-30% of a polymer of ethylene with a C3-C10 α-olefin and optionally a diene, wherein the polymer of ethylene has an ethylene content higher than 45% and an intrinsic viscosity [η] value from 3 to 5 dl/g.A particular advantage of the present invention is that articles comprising the above heterophasic polyolefin composition show a low ductile to brittle transition temperature (DBTT).
US08487040B2	Flame and smoke spread retardant molding compounds and components molded from these compounds HVAC and building and construction components are molded from novel compositions that meet the flame spread and smoke index, as well as the molding, safety, strength, and aesthetic requirements for this use. These compounds are based on a polyester resin and more specifically can be an polypropylene glycol dicyclopentadiene copolymerized with maleic anhydride, a low profile additive and hydroxy ethyl methacrylate monomer with additional additives including an appropriate catalyst package, a mold release agent, a thickening agent, a loading of aluminum hydroxide which is from about 40 to 65% by weight, and having a loading of glass fibers of from about 10 to about 25%.
US08487038B2	Polycarbonate and process for producing the same The invention relates to polycarbonate containing a dianhydrohexitol residue, obtainable from a polysaccharide, and a polyol residue, wherein the polycarbonate comprises between 0.2 and 5 mmol hydroxyl groups per gram polymer. The polycarbonate may be branched and comprises functional groups that can react with suitable crosslinkers. The polycarbonate can be used in for example coating compositions.
US08487036B2	Self-dispersing latex particulates The present invention is drawn to a self-dispersing latex particulate. The self-dispersing latex particulate can include a plurality of polymerized monomers witch form a latex particulate and a latex dispersant. The latex dispersant can include at least one hydrophobic segment adsorbed on a surface of the latex particulate, and a plurality of hydrophilic segments attached to the hydrophobic segment or segments. Such self-dispersing latex particulates can be included in latex dispersions, such as ink-jet inks.
US08487033B2	Thermoplastic elastomer compositions, methods for making the same, and articles made therefrom Provided are thermoplastic elastomer compositions composed of a thermoplastic component, an elastomeric component, and at least one particulate composition. Particulate compositions are composed of a particulate material and a carrier medium. Exemplary particulate materials include minerals, mineral compounds, including mineral oxides, clays, carbon, nanotubes, and combinations thereof. Typical carrier mediums are one or more polar polymers, apolar polymers, one or more oils, poly α-olefins, or combinations thereof. The at least one particulate composition is dispersed within the thermoplastic component and/or the elastomeric component. Particulate compositions include clay grease compositions wherein a clay, e.g., an exfoliated clay, is utilized as a thickener.
US08487024B2	Polyamide, polyamide composition, and method for producing polyamide The present invention relates to a polyamide obtainable by polymerizing an (a) dicarboxylic acid comprising at least 50 mol % of an alicyclic dicarboxylic acid and a (b) diamine comprising at least 50 mol % of a diamine having a substituent branched from a main chain.
US08487023B2	Nucleating agents for polyhydroxyalkanoates Provided herein are nucleating agent compositions for use in nucleating polymers during processing. Methods for making and using the nucleating agent compositions are also provided. The nucleating agent in dry powder form is wet milled in a liquid carrier, such as a plasticizer, surfactant, or lubricant.
US08487016B2	Dental impression material containing rheological modifiers and process of production The invention relates to a dental impression material containing a rheological modifier. The rheological modifier is in particular useful for adjusting shear-thinning properties of non-water based dental impression materials, especially of precision impression materials. It further relates to a method for producing a dental impression material.
US08487013B2	Production method of porous resin particle having hydroxyl group The present invention relates to a method for producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, the method including: dissolving a monomer mixture containing an aromatic vinyl compound, an aromatic divinyl compound and a (meth)acrylic acid ester having one hydroxyl group within the molecule thereof, and a polymerization initiator in an organic solvent to obtain a solution containing the monomer mixture and the polymerization initiator; suspending the solution in water in the presence of a dispersion stabilizer; and performing a suspension copolymerization. The method of the invention is capable of easily producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, that is used as a support for solid phase synthesis and enables efficient nucleic acid synthesis.
US08487012B2	Open celled foams, implants including them and processes for making same Described herein are open celled foams including a matrix of interconnected spheres. Also described herein are methods of making open celled foams as well as making composite members with open celled foam coatings covering at least a portion of the composite member. The open celled foams described herein are silicone based materials and can be used to coat implants such as breast implants and function to encourage tissue ingrowth and reduce capsular formation.
US08487009B2	1,2-diphenylethene derivatives for treatment of immune diseases The invention provides novel 1,2-diphenylethene derivatives and pharmaceutically acceptable salts thereof, the process for production of these compounds and their pharmaceutical composition and the use of these compounds as modulators of T-cells, neutrophils, macrophages and their associated cytokines as agents for treating immune, inflammatory and auto-immune diseases.
US08487005B2	Tranexamic acid formulations Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.
US08487004B2	Local treatment of neurofibromas A method for treating a neurofibroma, e.g. dermal neurofibroma, a subdermal neurofibroma, or a superficial plexiform neurofibroma, in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a neurofibroma either topically or intralesionally. This method does not encompass systemic administration of the composition to the subject to have an effect on the neurofibromas. Compositions useful for such treatments and methods of preparing the compositions are disclosed.
US08487001B2	Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors A composition and method for promoting neutrophil survival and activation such as the treatment of neutropenia arising as an undesirable side effect of chemotherapy and radiation therapy. A composition containing medium-chain fatty acids, such as Capri acid or caprylic acid, or salts or triglycerides thereof, or mono- or diglycerides or other analogues thereof or medium-chain triglycerides (MCT) is administered to a human or animal needing treatment in an amount sufficient to reduce or eliminate neutropenia. The composition is administered in an amount effective to treat the disorder. The methods are also useful in the management of bone narrow transplantation and in the treatment of various neutropenic diseases.
US08487000B2	Compound for the treatment of metabolic disorders Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
US08486998B2	Compositions for prevention/prophylactic treatment of poison ivy dermatitis The present invention, in one or more embodiments, comprises water-soluble derivatives of 3-n-pentadecylcatechol (poison ivy urushiol saturated congener) and/or 3-n-heptadecylcatechol (poison oak urushiol saturated congener) as compositions for the prevention and/or prophylactic treatment of contact dermatitis caused by poison ivy and poison oak. The present invention is also directed towards processes for making such compounds. Disclosed are compounds which are effective for tolerizing and desensitizing a subject against allergens contained in plants of the Anacardiaceae and Ginkgoaceae families comprising water soluble urushiol esters of general formula (I) Tolerizing and desensitizing mammals, including humans, to allergens contained in plants of the Anacardiaceae and Ginkgoaceae families is attained by administering a composition containing at least one water soluble urushiol ester compound.
US08486996B2	Aroylfuranes and aroylthiophenes The invention relates to novel substituted 2-(phenyl-, pyridyl- or pyrimidyl-carbonyl)-furanes and -thiophenes and related phenoxy/phenylthio-acetophenones and corresponding heterocyclic compounds, processes for the preparation thereof, pharmaceutical compositions containing same, the use thereof optionally in combination with one or more other pharmaceutically active compounds for the therapy of neoplastic diseases and autoimmune diseases, and a method for the treatment of such a diseases.
US08486991B2	Enantiomerically pure phosphoindoles as HIV inhibitors 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
US08486988B2	Crystalline chemotherapeutic N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N′-(2-fluoro-5-methylphenyl)urea Hydrate Crystalline Form 1, ways to make it, formulations comprising it and made with it and methods of treating patients having disease using it are disclosed.
US08486974B2	Efficient aspirin prodrugs Aspirin is one of the most widely used drugs in the treatment of inflammation, pain and fever. It has more recently found application in the prevention of heart attacks and stroke and is being studied as a cancer chemopreventative agent. Despite its value aspirin continues to be underutilized because it causes gastric bleeding. The technology under development potentially removes this problem. It is designed to reduce contact between the drug and the intestinal lining. An isosorbide aspirinate prodrug compound is thus provided. The compound has the general structure as shown in general formula (I) wherein Y is a C1-C8 alkyl ester, a C1-C8 alkoxy ester, a C3-C10 cycloalkyl ester, an arylester, a C1-C8 alkylaryl ester or —C(O)ORring, wherein Rring is a 5-membered aromatic or nonaromatic 5-member ring having at least one heteroatom substituted for a carbon of the ring system, which can be unsubstituted or substituted with at least one nitric oxide releasing group.
US08486969B2	Therapeutic compounds Disclosed herein is compound having a structure Therapeutic methods, compositions, and medicaments are also disclosed herein.
US08486964B2	Fused pyrrolidino-cyclopropane derivatives as selective 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors The present invention relates to fused pyrrolidino-cyclopropane derivatives according to formulae (I) to (IV) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11-β-HSD-1) and the use of such compounds for the treatment and/or prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.
US08486963B2	Azaindolizines and methods of use The invention relates to azaindolizines of formula I-a or I-b with anti-cancer and/or anti-inflammatory activity and more specifically to azaindolizines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.
US08486962B2	Antifungal agents Compounds of formula (I), and pharmaceutically acceptable salts thereof, may be used in therapy, for example as antifungal agents: (I) wherein: R1, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. Certain compounds of formula (I) are also provided. Compounds of formula (T), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.
US08486961B2	Pyrrolo[4,3,2-de]quinolin-8-amine compounds and methods of their preparation and use The present invention relates to compounds of formula I: methods of their use, processes for their preparation and isolated actinomycetes strains capable of preparing pyrrolo[4,3,2-de]quinolin-8-amine compounds.
US08486953B2	Thienopyrimidines for pharmaceutical compositions The present invention relates to novel pharmaceutical compositions comprising thienopyrimidine compounds. Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.
US08486951B2	Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including, but not limited to, malignant melanomas, solid tumors, glioblastomas, ovarian cancer, pancreatic cancer, prostate cancer, lung cancers, breast cancers, kidney cancers, hepatic cancers, cervical carcinomas, metastasis of primary tumor sites, myeloproliferative diseases, chronic myelogenous leukemia, leukemias, papillary thyroid carcinoma, non-small cell lung cancer, mesothelioma, hypereosinophilia syndrome, gastrointestinal stromal tumors, colonic cancers, ocular diseases characterized by hyperproliferation leading to blindness including various retinopathies, diabetic retinopathy, rheumatoid arthritis, asthma, chronic obstructive pulmonary disease, mastocytosis, mast cell leukemia, and diseases caused by PDGFR-α kinase, PDGFR-β kinase, c-KIT kinase, cFMS kinase, c-MET kinase, and oncogenic forms, aberrant fusion proteins and polymorphs of any of the foregoing kinases.
US08486947B2	Treatment of Parkinson's disease, obstructive sleep apnea, dementia with Lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3-receptor ligands The present invention provides new method of treatment of Parkinson's disease, obstructive sleep apnea, narcolepsy, dementia with Lewy bodies, vascular dementia with non-imidazole alkylamine derivatives that constitute antagonists of the H3-receptors of histamine.
US08486941B2	Phenyl amino pyrimidine compounds and uses thereof The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.
US08486940B2	Inhibitors The invention relates to novel pyrrolidine derivatives of formula (I): wherein R1, R2 and R3 are as defined herein, as inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5). QC catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate residues into pyroglutamic acid under liberation of water.
US08486937B2	Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and use thereof The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
US08486935B2	Xinafoate salt of N4-(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy)phenyl]2,4-pyrimidinediamine The present invention relates to the xinafoate salt of N4-[(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy)phenyl]-2,4-pyrimidinediamine. This compound is a suitable drug substance and is useful in the treatment of conditions including asthma.
US08486933B2	Pyrimidine inhibitors of kinase activity Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein L1, R1, R2, R3, R4, R5, and m are defined in the description. Methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.
US08486931B2	Substituted oxindole compounds The present invention relates to compounds of the general formula (I) in which A, B, R1, R2 and Het have the meaning given in claim 1; Y is a bivalent group of the formula in which D is C1-C3-alkylene, where D may have a substituent R5; R3 is hydrogen, C1-C8-alkyl or together with R4 is C1-C3-alkylene which may have a radical R5a, or together with R5 is C1-C3-alkylene, and R4 is hydrogen, C1-C8-alkyl or together with R3 is C1-C3-alkylene which may have a radical R5a, or together with R5 is C1-C3-alkylene, where R5 together with R5a, where present, are a bond or C1-C3-alkylene; and where one of the following conditions is satisfied: R3 together with R4 is C1-C3-alkylene which may have a radical R5a; or R3 together with R5 is C1-C3-alkylene; or R4 together with R5 is C1-C3-alkylene where the radical A is different from phenyl when the radical B is phenyl or naphthyl; and medicaments which comprise such compounds and the use thereof for the prophylaxis and/or treatment of vasopressin-dependent and/or oxytocin-dependent diseases.
US08486922B2	Composition This disclosure relates to a pharmaceutical composition that includes a first agent selected from the group consisting of an oxidative phosphorylation inhibitor, an ionophore, and an adenosine 5′-monophosphate-activated protein kinase (AMPK) activator; a second agent that possesses anti-inflammatory activity; and a third agent that is a serotonin metabolite.
US08486920B2	Composition and method for controlling plant diseases The present invention provides a composition for controlling plant diseases comprising, as active ingredients, ethaboxam and tolclofos-methyl.
US08486918B2	Phenyl oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor The present invention relates to novel phenyl oxadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
US08486912B2	MicroRNA fingerprints during human megakaryocytopoiesis Described herein is a method of decreasing expression of MAFB in a subject having a cancer and/or myeloproliferative disorder associated with overexpression of a MAFB gene product where an effective amount of at least one miR-130a gene product or an isolated variant or biologically-active fragment thereof is administered to the subject sufficient to decrease expression of the MAFB gene product in the subject.
US08486911B2	Th1-associated microRNAs and their use for tumor immunotherapy Described herein is the identification of miRNAs (miRs) that are up-regulated in Th1 cells compared to Th2 cells (referred to herein as Th1-associated miRs). In particular, the miR-17-92 gene cluster was found to exhibit significantly greater expression in Th1 cells. Over-expression of miR-17-92 in T cells promotes the Th1 phenotype. Thus, the use of Th1-associated miRs for cancer immunotherapy is described. Provided herein are isolated T cells containing a heterologous nucleic acid molecule encoding a Th1-associated miR, such as the miR17-92 gene cluster, or a portion thereof. Further provided is a method of treating cancer in a subject by administering to the subject an isolated T cell as disclosed herein. Also provided is a method of treating a subject with cancer by transfecting isolated T cells obtained from the subject with a heterologous nucleic acid molecule encoding a Th1-associated miR and administering the transfected T cells to the subject.
US08486909B2	Compositions and methods for the diagnosis and treatment of inflammatory disorders and fibrotic disease Compositions and methods are disclosed for the treatment and diagnosis of inflammatory diseases and disorders, including pulmonary diseases and fibrotic disorders, including COPD.
US08486908B2	Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response The invention provides novel immune regulatory oligonucleotides (IRO) as antagonist of TLRs and methods of use thereof. These IROs have unique sequences that inhibit or suppress TLR-mediated signaling in response to a TLR ligand or TLR agonist. The methods may have use in the prevention and treatment of cancer, an autoimmune disorder, airway inflammation, inflammatory disorders, infectious disease, skin disorders, allergy, asthma or a disease caused by a pathogen.
US08486905B2	Use of FLJ25416 gene Provided are a composition for diagnosing cancer or screening an anticancer drug comprising an FLJ25416 gene or an antibody directed to a protein expressed from the FLJ25416 gene, a composition for treating cancer comprising an inhibitor of the gene or an inhibitor of the protein expressed from the gene and a pharmaceutically acceptable carrier, and a kit for diagnosing cancer comprising at least one of the FLJ25416 gene and the protein expressed from the FLJ25416 gene. The FLJ25416 gene is expressed at high level in specific cancer cells, and induces an increase in proliferation rate of normal cells. The expression of the gene is suppressed, which results in an inhibitory effect on cancer cell growth. Thus, the FLJ25416 gene can be used as a target gene for diagnosis or treatment of cancer.
US08486903B2	TAZ/WWTR1 for diagnosis and treatment of cancer We provide an anti-TAZ agent for the treatment, prophylaxis or alleviation of cancer. We further provide a kit for detecting breast cancer in an individual or susceptibility of the individual to breast cancer comprising means for detection of TAZ expression in the individual or a sample taken from him or her as well as a method of detecting a cancer cell, the method comprising detecting modulation of expression, amount or activity of TAZ in the cell.
US08486899B2	Antioxidant To provide an antioxidant which is highly safe, inhibits oxidation of a biological component, in particular, a lipid, and is used as a drug, food or drink, a food additive, an external preparation for skin, or the like. The antioxidant contains 3-O-β-D-glucopyranosyl-4-methylergost-7-en-3-ol as an active ingredient.
US08486897B2	C-aryl glycoside compounds for the treatment of diabetes and obesity Compounds of formula (I) and pharmaceutically acceptable salts thereof, for use in the prevention and treatment of diseases including diabetes.
US08486895B2	Anti-epidermal growth factor receptor antibodies and uses thereof The present invention discloses humanized anti-epidermal growth factor receptor antibodies, which have favorable binding activity (the binding affinity being 5.09×10−10 mol/L) and are able to inhibit the growth and migration of tumor cells. The present invention also discloses the preparation methods and uses of the antibodies.
US08486890B2	Amylin derivatives The present invention relates to novel amylin derivatives having a protracted action profile, to pharmaceutical compositions comprising these derivatives and to the use of the derivatives for the treatment of diseases related to obesity, diabetes and other metabolic disorders.
US08486887B2	Enhancement of Bacillus thuringiensis Cry protein toxicities to coleopterans, and novel insect cadherin fragments The subject invention relates in part to the discovery that a fragment from a cadherin of the western corn rootworm enhances Cry3 toxicity to larvae of naturally susceptible species. The subject invention also relates in part to the discovery that a cadherin fragment from a beetle enhances Cry3Aa and Cry3Bb toxicity to coleopteran larvae, particularly those in the family Chrysomelidae. Such cadherin fragments are referred to as Bt Boosters (BtBs). The subject invention can be extended to the use of BtBs with other coleopteran-toxic Cry proteins for controlling a wide range of coleopterans.
US08486886B2	Botulinum toxin treatments A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
US08486879B2	Hypochlorite denture compositions and methods of use A solid composition including calcium and/or magnesium hypochlorite, a builder (e.g., one or more of carbonate, bicarbonate, sesquicarbonate), an acid, a water-soluble polymer, at least one anionic surfactant, and optionally, a hydrotrope. The composition does not include any potassium hypochlorite, sodium hypochlorite, lithium hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, or carboxylic acids that also have hydroxyl, amino, amido, imino, or imido groups. Upon dissolution of the composition in water, the calcium and/or magnesium hypochlorite and acid react to form hypochlorous acid. The use of hypochlorous acid, rather than direct use of an alkaline or alkaline earth hypochlorite results in a composition that is typically acidic rather than basic, and that results in improved cleaning. The composition is particularly suited for cleaning and disinfecting dentures.
US08486873B2	Lubricating oil compositions containing epoxide antiwear agents A lubricating oil composition comprising (a) a major amount of an oil of lubricating viscosity; and (b) an oil soluble epoxide compound having the following structure: wherein X is hydrogen or a substituted or unsubstituted C1 to C20 hydrocarbyl group, wherein the substituted hydrocarbyl group is substituted with one or more substituents selected from hydroxyl, alkoxy, ester or amino groups and Y is —CH2OR, —C(═O)OR1 or —C(═O)NHR2, wherein R, R1 and R2 are independently hydrogen or C1 to C20 alkyl or alkenyl groups;—and further wherein the oil of lubricating viscosity does not contain a carboxylic acid ester.
US08486870B1	Textured surfaces to enhance nano-lubrication Embodiments of the present invention may provide textured surfaces to be lubricated, the texturing to enhance the effectiveness of the intended nano-lubrication. The texturing may make asperities and depressions in the surface to be lubricated. This texturing may be executed, for example, by chemical etching, laser etching, or other techniques. This texturing may create locations in the lubricated surface to hold or anchor the intended nano-lubricants, to facilitate the creation of a tribo-film on the surface when the lubricated surface is used under pressure, and resulting in delivery of multiple chemistries from the nano-lubricant.
US08486865B2	Methods for detecting modification resistant nucleic acids Methods are provided for, inter alia, detecting nucleic acid molecules resistant to degradation, such as a plurality of RNA molecules bound to a ribosome, using various technologies including deep sequencing.
US08486862B2	Compositions and methods for improving the compatibility of water soluble herbicide salts The compatibility of aqueous herbicide solutions containing water soluble salts of 2,4-D and glyphosate in the presence of inorganic cations is improved by the addition of polyethylenimine or polyvinylamine crystallization inhibitors.
US08486852B2	Catalyst for diesel particle filter, preparation method of the same, and soot reduction device of diesel engine including the same A catalyst for diesel particle filter includes a platinum (Pt)-neodymium (Nd) alloy that is carried in silica, a preparation method thereof and a soot reduction device for diesel engine including the same, wherein the catalyst for diesel particle filter can maintain high catalyst activity and implement high nitrogen monoxide (NO) conversion efficiency even though it is used under the high temperature or vulcanization condition for a long time.
US08486851B2	Process for manufacturing a ceramic composite based on silicon nitride and β-eucryptite A process for manufacturing a sintered ceramic composite, based on silicon nitride and β-eucryptite, includes a step of producing a first powder blend, consisting of a powder of silicon nitride in crystalline form and a powder of a first lithium aluminosilicate in crystalline form, the composition of which is the following: (Li2O)x(Al2O3)y(SiO2)z, the lithium aluminosilicate composition being such that the set of molar fractions (x,y,z) is different from the set (1,1,2).
US08486844B2	Method and system for isolated and discretized process sequence integration A system for processing a semiconductor substrate is provided. The system includes a mainframe having a plurality of modules attached thereto. The modules include processing modules, storage modules, and transport mechanisms. The processing modules may include combinatorial processing modules and conventional processing modules, such as surface preparation, thermal treatment, etch and deposition modules. In one embodiment, at least one of the modules stores multiple masks. The multiple masks enable in-situ variation of spatial location and geometry across a sequence of processes and/or multiple layers of a substrate to be processed in another one of the modules. A method for processing a substrate is also provided.
US08486842B2	Method of selectively removing patterned hard mask A method of selectively removing a patterned hard mask is described. A substrate with a patterned target layer thereon is provided, wherein the patterned target layer includes a first target pattern and at least one second target pattern, and the patterned hard mask includes a first mask pattern on the first target pattern and a second mask pattern on the at least one second target pattern. A first photoresist layer is formed covering the first mask pattern. The sidewall of the at least one second target pattern is covered by a second photoresist layer. The second mask pattern is removed using the first photoresist layer and the second photoresist layer as a mask.
US08486839B2	Methods and apparatus to improve reliability of isolated vias A method for tiling selected vias in a semiconductor device is provided. The semiconductor device includes a plurality of vias. The method includes: generating a layout database for the semiconductor device; identifying isolated vias of the plurality of vias; selecting the isolated vias; defining a zone around each of the selected isolated vias; and adding tiling features on a metal layer above the selected isolated vias and within the zone. The method improves reliability of the semiconductor device by allowing moisture to vent from around the vias.
US08486835B2	Czochralski growth of randomly oriented polysilicon and use of randomly oriented polysilicon dummy wafers Non-production wafers of polycrystalline silicon are placed in non-production slots of a support tower for thermal processing monocrystalline silicon wafers. They may have thicknesses of 0.725 to 2 mm and be roughened on both sides. Nitride may be grown on the non-production wafers to a thickness of over 2 μm without flaking. The polycrystalline silicon is preferably randomly oriented Czochralski polysilicon grown using a randomly oriented seed, for example, CVD grown silicon. Both sides are ground to introduce sub-surface damage and then oxidized and etch cleaned. An all-silicon hot zone of a thermal furnace, for example, depositing a nitride layer, may include a silicon support tower placed within a silicon liner and supporting the polysilicon non-production wafers with silicon injector tube providing processing gas within the liner.
US08486831B2	Semiconductor device manufacturing method A miniaturized semiconductor device is provided by reducing the design thickness of a wiring line protecting film covering the surface of a wiring layer, and reducing the distance between the wiring layer and via plugs formed by a self-aligning process. Dummy mask layers extending in the same layout pattern as the wiring layer is formed above the wiring layer covered with a protecting film composed of a cap layer and side wall layers. In the self-aligning process for forming via plugs in a self-aligned manner with the wiring layer and its protecting film, the thickness of the cap layer is reduced and the design interval between the via plugs is reduced, whereby the miniaturization of the semiconductor device is achieved.
US08486830B2	Via forming method and method of manufacturing multi-chip package using the same A via forming method that includes forming via-holes in a substrate is provided. The method includes putting the substrate, having the via-holes, in a first solution to fill the via-holes with the first solution. Metal particles are sunk into the via-holes by supplying a second solution containing the metal particles to the first solution. A first curing process of heat-treating the substrate is performed so as to form vias in the via-holes. A multi-chip package that includes the substrate having the vias is also provided.
US08486827B2	Device of filling metal in through-via-hole of semiconductor wafer and method using the same A device of filling metal in a through-via-hole formed in a semiconductor wafer and a method of filling metal in a through-via-hole using the same are disclosed. A device of filling metal in a through-via-hole formed in a semiconductor wafer includes a jig base comprising a jig configured to fix the wafer having the through-via-hole formed therein; a upper chamber 120 installed on the jig base; a lower chamber installed under the jig base; a heater installed in the upper chamber, the heater configured to apply heat to filling metal placed on the wafer to melt the filling metal; and a vacuum pump configured to generate pressure difference between the upper chamber and the lower chamber by the pressure of the lower chamber reduced by discharging air of the lower chamber 130 outside, only to fill the melted filling metal in the through-via-hole.
US08486826B2	Process of forming a grid electrode on the front-side of a silicon wafer A process of forming a front-grid electrode on a silicon wafer having an ARC layer, comprising the steps: (1) printing and drying a metal paste A comprising an inorganic content comprising 0.5 to 8 wt.-% of glass frit and having fire-through capability, wherein the metal paste A is printed on the ARC layer to form a bottom set of thin parallel finger lines, (2) printing and drying a metal paste B comprising an inorganic content comprising 0.2 to 3 wt.-% of glass frit over the bottom set of finger lines, wherein the metal paste B is printed in a grid pattern which comprises (i) thin parallel finger lines forming a top set of finger lines superimposing the bottom set of finger lines and (ii) busbars intersecting the finger lines at right angle, and (3) firing the double-printed silicon wafer, wherein the inorganic content of metal paste B contains less glass frit plus optionally present other inorganic additives than the inorganic content of metal paste A.
US08486822B2	Semiconductor device having dummy pattern and the method for fabricating the same A method for fabricating a semiconductor device includes forming an interlayer dielectric film on a semiconductor substrate including a pattern region and a dummy region, forming a photoresist pattern on the interlayer dielectric film such that the pattern region and the dummy region are partially exposed, etching the interlayer dielectric film exposed through the photoresist pattern as an etching mask to form a contact hole and a dummy contact hole, filling the contact hole and the dummy contact hole with a conductive material to form a contact plug and a dummy plug, depositing a semiconductor layer on the contact plug and the dummy plug, and subjecting the semiconductor layer to patterning to form a semiconductor layer pattern and a dummy pattern.
US08486821B1	Method and apparatus for variable conductance A method of combinatorially processing a substrate and combinatorial processing chamber are provided. The processing chamber includes opposing annular rings defining a conductance gap that extends radially outward. The opposing annular rings are configured to vary the conductance gap in-situ. The variation of the conductance gap is another parameter for processing regions of a substrate differently to evaluate the impact of the conductance variation on a deposition process.
US08486820B2	Semiconductor device manufacturing method A semiconductor device manufacturing method includes: forming a first insulating film over the surface of a semiconductor substrate having at least two adjacent protrusions in such a manner that the film thickness between the two protrusions is not less than 1.2 times the height of at least one of the two protrusions; and forming a second insulating film over the first insulating film, the second insulating film being harder than the first insulating film.
US08486817B2	Method for forming an integrated circuit level by sequential tridimensional integration A method for forming a level of a tridimensional structure on a first support in which components are formed, including the steps of forming, on a second semiconductor support, a single-crystal semiconductor substrate with an interposed thermal oxide layer; placing the free surface of the single-crystal semiconductor substrate on the upper surface of the first support; eliminating the second semiconductor support; and thinning down the thermal oxide layer down to a thickness capable of forming a gate insulator.
US08486816B2	Diamond semiconductor element and process for producing the same An integrated optical waveguide has a first optical waveguide, a second optical waveguide, and a groove. The second optical waveguide is coupled to the first optical waveguide and has a refractive index that is different from the first optical waveguide. The groove is disposed so as to traverse an optical path of the first optical waveguide and is separated from an interface between the first optical waveguide and the second optical waveguide by a predetermined spacing. The spacing from the interface and the width of the groove are determined such that reflection at a boundary between the first optical waveguide and the second optical waveguide is weakened. A semiconductor board may be disposed at a boundary between the first optical waveguide and the second optical waveguide. In this case, the width of the groove and the thickness of the semiconductor board are determined such that light reflected off an interface between the first optical waveguide and the groove is weakened by light reflected from an interface between the groove and the semiconductor board, and by light reflected from an interface between the semiconductor board and the second optical waveguide.
US08486813B2	Silicon wafer and fabrication method thereof A silicon wafer and fabrication method thereof are provided. The silicon wafer includes a first denuded zone formed with a predetermined depth from a top surface of the silicon wafer, the first denuded zone being formed with a depth ranging from approximately 20 μm to approximately 80 μm from the top surface, and a bulk area formed between the first denuded zone and a backside of the silicon wafer, the bulk area having a concentration of oxygen uniformly distributed within a variation of 10% over the bulk area.
US08486812B2	Fabrication method for polycrystalline silicon thin film and display device fabricated using the same The present invention relates to a fabrication method for polycrystalline silicon thin that is capable of providing uniform crystallization of polycrystalline silicon thin film by laser using a mask having a mixed structure of laser transmission regions and laser non-transmission regions, wherein the laser transmission regions exist asymmetrically on the basis of a laser scanning directional axis, and the laser transmission regions exist symmetrically on the basis of a certain central axis, and the laser transmission regions are shifted to a certain distance on the basis of another axis parallel to the certain central axis, so that the laser transmission regions and non laser transmission regions are alternately positioned.
US08486811B2	Semiconductor device and manufacturing process therefor A process for manufacturing a semiconductor device, in which a current flows in a deflected part that includes a semiconductor, includes forming a straight beam having a doubly-clamped beam structure that includes the semiconductor by forming a void under the beam, filling the void with a liquid, and contacting a center of the beam with a bottom of the void by drying the liquid to form the deflected part.
US08486808B2	Manufacturing method of semiconductor device having vertical transistor A method of manufacturing a semiconductor device includes forming a gate electrode material that covers a gate insulating film formed on each of side surfaces of first and second silicon pillars, wherein a film formation amount of the gate electrode material is controlled so that a first part with which the side surface of the first silicon pillar is covered via the gate insulating film does not contact with a second part with which the side surface of the second silicon pillar is covered via the gate insulating film. The method further includes: forming a mask insulating film that covers the first and second parts and fills a region between the first and second parts; and etching the gate electrode material using the mask insulating film as a mask, thereby forming gate electrodes with which the side surfaces of the first and second silicon pillars are covered via the gate insulating film, respectively and a conductive film electrically connecting the gate electrodes to each other.
US08486804B2	Semiconductor device A semiconductor device including a first element including a photodiode and an amplifier circuit which amplifies output current of the photodiode, over a first insulating film; and a second element including a color filter and an overcoat layer over the color filter over a second insulating film is manufactured. The first element and the second element are attached to each other by bonding the first insulating film and the second insulating film with a bonding material. Further, the amplifier circuit is a current mirror circuit including a thin film transistor. Still further, a color film may be used instead of a color filter.
US08486803B2	Wafer level packaging method of encapsulating the bottom and side of a semiconductor chip A chip-scale packaging method, with bottom and side of a semiconductor chip encapsulated, includes the following steps: attaching backside of a thinned semiconductor wafer to a dicing tape; separating individual chips by cutting from front side of the wafer at scribe line but not cut through the dicing tape; flipping and attaching the wafer onto a top surface of a double-sided tape, then removing the dicing tape; attaching bottom surface of the double-sided tape on a supporting plate; filling the space between adjacent chips and covering the whole wafer backside with a molding material; flipping the whole structure and remove the supporting plate; placing solder balls at corresponding positions on electrodes of each chip and performing backflow treatment; finally separating individual chip packages by cutting through molding material at the space between adjacent chip packages with molding material encapsulating the bottom and side of each individual semiconductor chip.
US08486797B1	Bipolar junction transistor with epitaxial contacts Bipolar junction transistors are provided in which at least one of an emitter contact, a base contact, or a collector contact thereof is formed by epitaxially growing a doped SixGe1-x layer, wherein x is 0≦x≦1, at a temperature of less than 500° C. The doped SixGe1-x layer comprises crystalline portions located on exposed surfaces of a crystalline semiconductor substrate and non-crystalline portions that are located on exposed surfaces of a passivation layer which can be formed and patterned on the crystalline semiconductor substrate. The doped SixGe1-x layer of the present disclosure, including the non-crystalline and crystalline portions, contains from 5 atomic percent to 40 atomic percent hydrogen.
US08486793B2	Method for manufacturing semiconductor device with semiconductor materials with different lattice constants A semiconductor device including a gate electrode disposed on a semiconductor substrate and source/drain regions disposed at both sides of the gate electrode, the source/drain regions being formed by implanting impurities. The source/drain regions include an epitaxial layer formed by epitaxially growing a semiconductor material having a different lattice constant from that of the semiconductor substrate in a recessed position at a side of the gate electrode, and a diffusion layer disposed in a surface layer of the semiconductor substrate.
US08486792B2	Film forming method of silicon oxide film, silicon oxide film, semiconductor device, and manufacturing method of semiconductor device A silicon compound gas, an oxidizing gas, and a rare gas are supplied into a chamber (2) of a plasma processing apparatus (1). A microwave is supplied into the chamber (2), and a silicon oxide film is formed on a target substrate with plasma generated by the microwave. A partial pressure ratio of the rare gas is 10% or more of a total gas pressure of the silicon compound gas, the oxidizing gas, and the rare gas, and an effective flow ratio of the silicon compound gas and the oxidizing gas (oxidizing gas/silicon compound gas) is not less than 3 but not more than 11.
US08486790B2	Manufacturing method for metal gate A manufacturing method for a metal gate includes providing a substrate having a dielectric layer and a polysilicon layer formed thereon, the polysilicon layer, forming a protecting layer on the polysilicon layer, forming a patterned hard mask on the protecting layer, performing a first etching process to etch the protecting layer and the polysilicon layer to form a dummy gate having a first height on the substrate, forming a multilayered dielectric structure covering the patterned hard mask and the dummy gate, removing the dummy gate to form a gate trench on the substrate, and forming a metal gate having a second height in the gate trench. The second height of the metal gate is substantially equal to the first height of the dummy gate.
US08486786B2	Enhancing uniformity of a channel semiconductor alloy by forming STI structures after the growth process When forming sophisticated gate electrode structures of transistor elements of different type, the threshold adjusting channel semiconductor alloy may be provided prior to forming isolation structures, thereby achieving superior uniformity of the threshold adjusting material. Consequently, threshold variability on a local and global scale of P-channel transistors may be significantly reduced.
US08486783B2	Semiconductor device and method of manufacturing the same A method of manufacturing a semiconductor device includes: forming a trench for forming buried type wires by etching a substrate; forming first and second oxidation layers on a bottom of the trench and a wall of the trench, respectively; removing a part of the first oxidation layer and the entire second oxidation layer; and forming the buried type wires on the wall of the trench by performing a silicide process on the wall of the trench from which the second oxidation layer is removed. As a result, the buried type wires are insulated from each other.
US08486781B2	Method of manufacturing flash memory device A method of manufacturing flash memory device is provided and includes the following steps. First, a substrate is provided. Then, a stacked gate structure is formed on the substrate. Subsequently, a first oxide layer is formed on the stacked gate structure. Following that, a nitride spacer is formed on the first oxide layer, wherein a nitrogen atom-introducing treatment is performed after the forming of the first oxide layer and before the forming of the nitride spacer. Accordingly, the nitrogen atom-introducing treatment of the presentation invention can improve the data retention reliability of the flash memory device.
US08486775B2	Thin film transistor array panel and method for manufacturing the same A manufacturing method of a thin film transistor (TFT) includes forming a gate electrode including a metal that can be combined with silicon to form silicide on a substrate and forming a gate insulation layer by supplying a gas which includes silicon to the gate electrode at a temperature below about 280° C. The method further includes forming a semiconductor on the gate insulation layer, forming a data line and a drain electrode on the semiconductor and forming a pixel electrode connected to the drain electrode.
US08486772B2	Method of manufacturing SOI substrate The method of one embodiment of the present invention includes: a first step of irradiating a bond substrate with ions to form an embrittlement region in the bond substrate; a second step of bonding the bond substrate to a base substrate with an insulating layer therebetween; a third step of splitting the bond substrate at the embrittlement region to form a semiconductor layer over the base substrate with the insulating layer therebetween; and a fourth step of subjecting the bond substrate split at the embrittlement region to a first heat treatment in an argon atmosphere and then a second heat treatment in an atmosphere of a mixture of oxygen and nitrogen to form a reprocessed bond substrate. The reprocessed bond substrate is used again as a bond substrate in the first step.
US08486770B1	Method of forming CMOS FinFET device A CMOS FinFET device and method for fabricating a CMOS FinFET device is disclosed. An exemplary CMOS FinFET device includes a substrate including a first region and a second region. The CMOS FinFET further includes a fin structure disposed over the substrate including a first fin in the first region and a second fin in the second region. The CMOS FinFET further includes a first portion of the first fin comprising a material that is the same material as the substrate and a second portion of the first fin comprising a III-V semiconductor material deposited over the first portion of the first fin. The CMOS FinFET further includes a first portion of the second fin comprising a material that is the same material as the substrate and a second portion of the second fin comprising a germanium (Ge) material deposited over the first portion of the second fin.
US08486768B2	Semiconductor device comprising high-k metal gate electrode structures and precision eFuses formed in the active semiconductor material In a complex semiconductor device, electronic fuses may be formed in the active semiconductor material by using a semiconductor material of reduced heat conductivity selectively in the fuse body, wherein, in some illustrative embodiments, the fuse body may be delineated by a non-silicided semiconductor base material.
US08486765B2	Structure and process for electrical interconnect and thermal management A method for making a structure for thermal management of circuit devices. The method provides a first substrate and a second substrate where at least one of the first and second substrates includes a circuit element. The method forms in at least one of the first substrate and the second substrate an entrance through-hole extending through a thickness of the first substrate or the second substrate, forms in at least one of the first substrate and the second substrate an exit through-hole extending through a thickness of the first substrate or the second substrate, forms respective bonding elements on at least one of the first and second substrates, and bonds the first and second substrates at the respective bonding elements to form a seal between the first and second substrates and to form a first coolant channel in between the first and second substrates.
US08486764B1	Wafer level package and fabrication method A method of forming an electronic component package includes coupling a first surface of an electronic component to a first surface of a first dielectric strip, the electronic component comprising bond pads on the first surface; forming first via apertures through the first dielectric strip to expose the bond pads; and filling the first via apertures with an electrically conductive material to form first vias electrically coupled to the bond pads. The bond pads are directly connected to the corresponding first vias without the use of a solder and without the need to form a solder wetting layer on the bond pads.
US08486759B2	Method for forming terminal of stacked package element and method for forming stacked package A semiconductor chip module having high degree of freedom in assignment of a circuit to each semiconductor chip and in position of a connection terminal of each semiconductor chip is provided. The present invention relates to a semiconductor chip module in which a plurality of semiconductor chips, each provided on the side face thereof with a part of a connection terminal coupled with a circuit pattern formed on the front face, have been stacked and bonded. Connection terminal portions on the side faces of the respective semiconductor chips are interconnected by a wiring pattern. The connection terminal on the semiconductor chip is led from the front face to the side face and formed by applying spraying of a conductive material in a mist state.
US08486757B2	Semiconductor device and method of packaging a semiconductor device with a clip A method and apparatus of packaging a semiconductor device with a clip is disclosed. The clip defines a first contact region and a second contact region on a same face of the at least one clip. The chip defines a first face, and a second face opposite to the first face, the first contact region being attached to the first face of the chip and the second contact region being located within a same plane with the second face of the clip.
US08486756B2	Flip chip bonded semiconductor device with shelf and method of manufacturing thereof The semiconductor device according to the present invention has a planar semiconductor chip having projecting connection terminals provided on one surface thereof. A shelf is provided where a peripheral edge of a surface of the semiconductor chip opposite one surface thereof onto which connection terminals are provided is removed. This makes it possible to secure a larger volume of the fillet portion of the underfill, thereby helping improve the function of preventing the rising up of the excess underfill by providing a shelf in the semiconductor chip.
US08486753B2	Patterning method of metal oxide thin film using nanoimprinting, and manufacturing method of light emitting diode Disclosed are a patterning method of a metal oxide thin film using nanoimprinting, and a manufacturing method of a light emitting diode (LED). The method for forming a metal oxide thin film pattern using nanoimprinting includes: coating a photosensitive metal-organic material precursor solution on a substrate; preparing a mold patterned to have a protrusion and depression structure; pressurizing the photosensitive metal-organic material precursor coating layer with the patterned mold; forming a cured metal oxide thin film pattern by heating the pressurized photosensitive metal-organic material precursor coating layer or by irradiating ultraviolet rays to the pressurized photosensitive metal-organic material precursor coating layer while being heated; and removing the patterned mold from the metal oxide thin film pattern, and selectively further includes annealing the metal oxide thin film pattern. Within this, there is provided a method for forming a metal dioxe thin film pattern using nano imprinting, which makes it possible to simplify the process for forming the pattern since the process of separately applying the ultraviolet resin to be used as the resist can be omitted, and forms a micro/nano composite pattern through a single imprint process.
US08486750B2	Solid-state imaging device and fabrication method thereof A fabrication method for solid-state imaging devices includes having circuitry formed on a substrate, forming a lower electrode layer on the circuitry, patterning the lower electrode layer to separate pixel-wise into a set of segments, and forming a compound-semiconductor film of chalcopyrite structure over a whole area of element regions. A resist layer is applied on the compound-semiconductor thin film to pixel-wise pattern in accordance with the lower electrode layer as a base separated into the set of segments, and an ion doping is applied over a whole area of element regions, forming element separating regions in the compound-semiconductor thin film. The method includes removing the resist layer for exposure of surfaces of as set of compound-semiconductor thin films separated pixel-wise by the element separating regions. A transparent electrode layer is formed in a planarizing manner over a whole area of element regions.
US08486742B2	Method for manufacturing high efficiency light-emitting diodes A method for manufacturing a light-emitting device comprising the steps of: providing a substrate comprising a first surface and a second surface; forming a plurality of cutting lines on the substrate by a laser beam; cleaning the substrate by a chemical solution; and forming a light-emitting stack on an first surface of the substrate after cleaning the substrate.
US08486741B2	Process for etching trenches in an integrated optical device The described process allows trenches to be etched in a structure comprising a support substrate and a multilayer, formed on the substrate, for the definition of wave guides of an integrated optical device and comprises a selective plasma attack in the multilayer through a masking structure that leaves uncovered areas of the multilayer corresponding to the trenches to be etched. Such a masking structure is obtained by forming a mask of metallic material on the multilayer that leaves uncovered the areas corresponding to the trenches to be etched and forming a mask of non-metallic material, for example photoresist, on it that leaves uncovered regions comprising at least part of the areas and an edge portion of the mask of metallic material.
US08486740B1	Method for manufacturing array substrate of transflective liquid crystal display A method for manufacturing an array substrate of a transflective LCD includes: (1) providing a substrate; (2) forming a transparent electrode layer on the substrate and forming a first metal layer on the transparent electrode layer; (3) applying a first photo-masking operation to form a gate terminal, a pixel electrode, and a reflector section; (4) forming an insulation layer on the gate terminal, the pixel electrode, and the reflector section; (5) applying a second photo-masking operation to form a gate insulation layer on the insulation layer; (6) forming a semiconductor layer on the gate insulation layer and forming a second metal layer on the semiconductor layer; and (7) applying a third photo-masking operation to form a channel layer on the semiconductor layer and also forming a drain terminal and a source terminal on the second metal layer, so as to form a thin-film transistor.
US08486738B2	Light emitting device having auto-cloning photonic crystal structures and manufacturing method thereof A light emitting device having auto-cloning photonic crystal structures comprises a substrate, a first semiconductor layer, an active emitting layer, a second semiconductor layer and a saw-toothed multilayer film comprising auto-cloning photonic crystal structures. The saw-toothed multilayer film provides a high reflection interface and a diffraction mechanism to prevent total internal reflection and enhance light extraction efficiency. The manufacturing methods of the light emitting device having auto-cloning photonic crystal structures are also presented.
US08486735B2	Method and device for incremental wavelength variation to analyze tissue A method of imaging a target using a miniaturized imaging device is disclosed comprising providing a miniaturized imaging device having a stationary lens system and an imaging array, wherein the distance from a distal end of the stationary lens system to the imaging array is fixed. The miniaturized imaging device is advanced near the desired target and a distance from a distal end of the stationary lens system to the desired target is determined. A desired wavelength of light is calculated based on the determined distance from the distal end of the stationary lens system to the desired target and the desired wavelength of light is propagated onto the target.
US08486732B2	Method of manufacturing semiconductor light emitting device including step of performing etching process with respect to conductive support member Disclosed are a light emitting device, a method of manufacturing the same, a light emitting device package, and a lighting system. The light emitting device includes a conductive support member, a light emitting structure layer including a first conductive semiconductor layer, an active layer, and a second conductive semiconductor layer on the conductive support member, and an electrode on the light emitting structure layer. The conductive support member has a curved lateral surface recessed inward.
US08486731B2	Light-emitting device and method for manufacturing light-emitting device A light-emitting device includes: a substrate; a light-emitting section provided on an upper surface of the substrate, the light-emitting section including an LED chip and a sealing resin containing fluorescent material covering the LED chip; and a silicon oxide insulating film provided between the substrate and the light-emitting section, the silicon oxide insulating film being formed directly on an upper surface of the substrate or an alumina insulating film, the sealing resin containing fluorescent material formed directly on an upper surface of the silicon oxide insulating film so as to cover the LED chip. Thus, this invention provides the light-emitting device capable of making the sealing resin difficult to be separated from the substrate and a method for manufacturing the light-emitting device.
US08486727B2	System and method for step coverage measurement Determining an unknown step coverage of a thin film deposited on a 3D wafer includes exposing a planar wafer comprising a first film deposited thereon to X-ray radiation to create first fluorescent radiation; detecting the first fluorescent radiation; measuring a number of XRF counts on the planar wafer; creating an XRF model of the planar wafer; providing a portion of the 3D wafer comprising troughs and a second film deposited thereon; determining a multiplier factor between the portion of the 3D wafer and the planar wafer; exposing the portion of the 3D wafer to X-ray radiation to create second fluorescent radiation; detecting the second fluorescent radiation; measuring a number of XRF counts on the portion of the 3D wafer; calculating a step coverage of the portion of the 3D wafer; and determining a uniformity of the 3D wafer based on the step coverage of the portion of the 3D wafer.
US08486723B1	Three axis magnetic sensor device and method A method and structure for a three-axis magnetic field sensing device is provided. The device includes a substrate, an IC layer, and preferably three magnetic field sensors coupled to the IC layer. A nickel-iron magnetic field concentrator is also provided.
US08486721B2	Magnetic beads for reducing leukocyte interference in immunoassays Methods and devices for reducing interference from leukocytes in an analyte immunoassay are provided. In one embodiment, a method is provided comprising the steps of amending a biological sample with magnetic sacrificial beads opsonized to leukocytes, binding leukocytes in the sample to the magnetic sacrificial beads, and magnetically retaining the beads out of contact from an immunosensor.
US08486718B2	Magnetic system A magnetic system for biosensors is switchable between attraction force and repulsion force near the sensor surface. The magnetic system includes a magnetic source and a sensor. The sensor corresponds with the magnetic field in a way that the magnetic source creates inhomogeneous magnetic field lines that results in a magnetic force towards the magnetic system and which subsequently or adjacently exerts a magnetic force directed away from the magnetic system with all magnetic forces generated at the same magnetic source.
US08486717B2	Lateral flow assays using two dimensional features The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control features, and the methods for detecting an analyte using the lateral flow devices, and processes for making the lateral flow devices.
US08486709B2	Optical nanosensors comprising photoluminescent nanostructures Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. Generally, the nanosensors comprise a photoluminescent nanostructure and a polymer that interacts with the photoluminescent nanostructure. In some cases, the interaction between the polymer and the nanostructure can be non-covalent (e.g., via van der Waals interactions). The nanosensors comprising a polymer and a photoluminescent nanostructure may be particularly useful in determining the presence and/or concentration of relatively small molecules, in some embodiments. In addition, in some instances the nanosensors may be capable of determining relatively low concentrations of analytes, in some cases determining as little as a single molecule. In some embodiments, the interaction between the analyte and the nanosensor (e.g., between the analyte and the photoluminescent nanostructure) can be reversible, which may allow, for example, for the reuse of a nanosensor after it has been exposed to an analyte.
US08486704B2	Methods of chromogen separation-based image analysis Methods for chromogen separation-based image analysis are provided, with such methods being directed to quantitative video-microscopy techniques in cellular biology and pathology applications.
US08486702B2	Method of tracking fluids produced from various zones in subterranean well A traceable treatment composition for treating a subterranean formation having multiple zones penetrated by a well bore comprising a homogenous blend of a tracking composition and a resin composition. The tracking composition comprises a substantially non-radioactive tracking material selected from the group consisting of a metal salt. The metal portion of the metal salt may be selected from the group consisting of gold, silver, lithium, molybdenum, and vanadium. The metal salt may also be selected from the group consisting of: barium bromide, barium iodide, beryllium fluoride, beryllium bromide, beryllium chloride, cadmium bromide, cadmium iodide, chromium bromide, chromium chloride, chromium iodide, cesium bromide, cesium chloride, sodium bromide, sodium iodide, sodium nitrate, sodium nitrite, potassium iodide, potassium nitrate, manganese bromide, zinc bromide, zinc iodide, sodium monofluoroacetate, sodium trifluoroacetate, sodium 3-fluoropropionate, potassium monofluoroacetate, potassium trifluoroacetate, and potassium 3-fluoropropionate.
US08486700B2	Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof The invention relates to methods and compositions for the differentiation of stromal cells from adipose tissue into hematopoietic supporting stromal cells and myocytes of both the skeletal and smooth muscle type. The cells produced by the methods are useful in providing a source of fully differentiated and functional cells for research, transplantation and development of tissue engineering products for the treatment of human diseases and traumatic tissue injury repair.
US08486699B2	Immortal unipotent porcine PICM-19H and PICM-19B stem cell lines Two cell lines, PICM-19H and PICM-19B, were derived from the bipotent ARS-PICM-19 pig liver stem cell line. The unipotent porcine stem cell line PICM-19H differentiates exclusively into hepatocytes and can be induced to express CYP450 enzymes. The growth rate and cell density in culture, morphological features, and hepatocyte detoxification functions, i.e., inducible CYP450 activity, ammonia clearance, and urea production of the PICM-19H cells were evaluated for their application in artificial liver devices. PICM-19H cells contain numerous mitochondria, Golgi apparatus, smooth and rough endoplasmic reticulum, vesicular bodies and occasional lipid vacuoles and display inducible CYP450 activity, clear ammonia, and produce urea in a glutamine-free medium. The data indicate that both cell lines, either together or alone, may be useful as the cellular substrate for an artificial liver device. The results demonstrate the potential for the use of PICM-19H cells in drug biotransformation and toxicity testing.
US08486694B2	Generation of antigen specific T cells The present invention is directed to a method of generating antigen specific T cells. Furthermore, the invention is directed to antigen specific T cells, isolated transgenic TCR's, pharmaceutical compositions containing same and their use in adoptive cell therapy. This invention in particular pertains to the use of cells co-expressing allogeneic MHC molecules and antigens to induce peptide-specific T cells from non-selected allogeneic T cell repertoires.
US08486693B2	Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods Modified antigen presenting cells provided herein have improved lifespan and immunogenicity compared to unmodified antigen presenting cells, and are useful for immunotherapy. The modified antigen presenting cells express an altered protein kinase, referred to herein as “Akt.” The altered Akt associates with the cell membrane with greater frequency than unaltered Akt, and is referred to herein as “membrane-targeted Akt.”
US08486690B2	Method to determine state of a cell exchanging metabolites with a fluid medium by analyzing the metabolites in the fluid medium The present invention relates to a method for determining the ideal time for and outcome of reproductive health procedures including in vitro fertilization by establishing a correlation between the successful outcome of said procedure and the spectra of a body fluid obtained using a chosen analytical modality for a population of patients, acquiring for a patient a spectrum of the body fluid of the patient using said chosen modality.
US08486688B2	Use of psychrophilic anaerobic digestion in sequencing batch reactor for degradation of prions The use or process of use of a sequencing batch reactor for eliminating prion in specified risk materials and for measuring the efficacy of a sequencing batch reactor to degrade prior proteins in specified risk materials are disclosed. The specified risk material is fed to a sequencing batch reactor containing a layer of acclimatized anaerobic sludge, and the specified risk material reacts with the sludge at a temperature below 25° C. so as to allow degradation of the prion protein.
US08486685B2	Cellular permissivity factor for viruses and uses thereof The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
US08486683B2	Beta-glucosidase enzymes Provided are modified beta-glucosidase enzymes, derived from the Trichoderma reesei Cel3A beta-glucosidase, that exhibit improvements in one or more kinetic parameters (KG, KG2, kcat) comprising amino acid substitutions at one or more of positions 43, 101, 260 and 543. Also provided are genetic constructs comprising nucleotide sequences encoding for modified beta-glucosidase enzymes, methods for the production of modified beta-glucosidase enzymes from host strains and the use of the modified beta-glucosidase enzymes in the hydrolysis of cellulose.
US08486681B2	Alpha-amylase variant with altered properties The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase.
US08486679B2	Perhydrolase variant providing improved specific activity An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.
US08486678B2	Pharmaceutical compositions for the treatment of virus infection The invention describes novel pharmaceutical compositions for the treatment of virus infections and cancer. The pharmaceutical compositions include mutant oligoadenylate synthetases (OAS) that have either enhanced cell permeability, reduced oxidative potential, improved antiviral activity, improved enzymatic activity, or absent enzymatic activity. The pharmaceutical compositions have improved drug properties and retain or have enhanced antiviral activity relative to their native forms. The pharmaceutical compositions further include chemically modified oligoadenylate synthetases, such chemical modifications being designed to increase serum stability and reduce immunogenicity in vivo. Such chemical modifications further increase drug stability and manufacturability in vitro. Compositions composed of more than ninety novel modifications are described. Also described are antibodies to polypeptides of the invention.
US08486676B2	Carriers for enzyme or cell immobilization and immobilization method using the carriers The invention discloses a carrier made from an organic foam having open pores for enzymes or cells immobilization and the methods for preparing immobilized enzymes or cells. The invention uses flocculation and crosslinking technology to immobilize enzyme protein or cells on the organic foam material having open pores. The resultant immobilized products have larger specific surface area, higher specific activity and can be made into various shapes.
US08486671B2	Method for the production of polyunsaturated fatty acids The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.
US08486664B2	Enzymatic production of an ethylenically unsaturated glycoside using polysaccharides Ethylenically unsaturated glycosides of formula I wherein Y, Y′, m, A, X, R3 and R4 have the meanings given in the description, are produced by reacting an ethylenically unsaturated compound of formula II with a polysaccharide comprising 10 or more monosaccharide units, such as starch, amylose, amylopectin, cellulose, in the presence of a glycosidase, such as an amylase, cellulase, glucosidase or and galactosidase, or a glycosyltransferase, such a cyclomaltodextrin glucanotransferase.
US08486663B2	Compositions and methods for generating antibodies The compositions and methods of the present invention comprise the efficient and effective presentation of antigens to the appropriate components of the immune system resulting in the production of species-specific antibodies in vitro. In general, these compositions comprise one or more antigenic components together with a colloidal metal, optionally combined with derivatized PEG (polyethylene glycol) or other agents. The invention also comprises methods and compositions for making such colloidal metal compositions.
US08486660B2	Methods and compositions for concentrating secreted recombinant protein Methods and compositions are described that relate to obtaining concentrated preparations of secreted recombinant proteins. These proteins are expressed in the form of fusion proteins with a chitin-binding domain (CBD). The fusion proteins are capable of being concentrated in the presence of chitin. Also described is: a shuttle vector that includes a modified LAC4 promoter; a chitinase-negative host cell; a CBD capable of eluting from chitin under non-denaturing conditions; and sterilized chitin, which can be optionally magnetized for facilitating recovery of recombinant protein.
US08486657B2	Anti-preproprotein and anti-preprotein antibodies as immunohistochemical markers It is disclosed herein that antibodies specific for preproproteins or preproteins, which are synthesized by certain types of cells or tissues, can be used in immunohistochemistry assays to discriminate between the intracellular component of the protein (including the preproprotein, preprotein and/or proprotein forms of the protein) from the secreted component of the same protein. Accordingly, provided herein is an immunohistochemical method for specific detection of the intracellular form of a protein in a biological sample using an antibody specific for the preproprotein or preprotein form of the protein. In particular examples, the protein is albumin or an immunoglobulin light chain. Also disclosed herein are preproprotein-specific ore preprotein-specific antibodies that can be used to detect specific cell types, tissue lesions or other pathological foci and metastases by IHC. In particular, antibodies that specifically bind human preproalbumin, but do not bind the secreted form of albumin are disclosed.
US08486656B2	Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine Presented is a method of prognosing a patient's response to a cancer therapy wherein prior to the therapy contacting a sample of cells from the patient's tissue or organ being treated for the cancer with a solution of TCPP to permit binding of the TCPP to components of the abnormal dysplastic or carcinomic cells, if any are present; detecting TCPP fluorescence in the sample, the presence of TCPP fluorescence being indicative that the sample contains dysplastic or carcinomic cells; at intervals during the therapy and subsequent to the therapy performing steps a-c on another sample of cells from the patient's tissue or organ being treated for the cancer; and determining if the percentage of abnormal pre-cancerous cells in the samples tested during and subsequent to the therapy are reduced as compared with the sample tested prior to the therapy, the reduction being prognostic of the patients response to the cancer therapy.
US08486655B2	Point source diffusion cell activity assay apparatus Apparatuses and methods for determining whether a test compound solution induces cell activity, an embodiment of the method of the present invention comprising placing a test compound solution in contact with a cell suspension media containing cells, diffusing the test compound solution into the cell suspension from a point source, and detecting activity in the cells with respect to their distance from the point source. Detecting activity in the cells can involve detecting activity in a first group of the cells proximate to the point source, and detecting activity in a second group of the cells farther from the point source than the first group.
US08486651B2	Method for treating a disorder associated with Eya dysregulation by modulating Eya phosphatase activity The present invention provides a novel mechanistic pathway and methods related to this pathway for the identification of compounds for the treatment of diseases involving cell proliferation, invasion and/or metastasis such as cancer. In particular, the instant invention relates to the phosphatase activity of Eya and the Eya-Six complex as a target for identifying novel therapeutic agents for the treatment of proliferative, invasive and/or metastatic disorders, and compositions identified using the methods disclosed herein.
US08486649B2	System and method for measuring an analyte in a sample Methods of determining a corrected analyte concentration in view of some error source are provided herein. The methods can be utilized for the determination of various analytes and/or various sources of error. In one example, the method can be configured to determine a corrected glucose concentration in view of an extreme level of hematocrit found within the sample. In other embodiments, methods are provided for identifying various system errors and/or defects. For example, such errors can include partial-fill or double-fill situations, high track resistance, and/or sample leakage. Systems are also provided for determining a corrected analyte concentration and/or detecting some system error.
US08486640B2	Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease A common long term problem after Ileal Pouch-Anal Anastomosis (IPAA) is the inflammation of the pouch, called pouchitis. Additionally, about 5-10% of patients undergoing IPAA with a diagnosis of ulcerative colitis at the time of surgery are subsequently diagnosed with Crohn's disease. In one embodiment, the present invention provides methods of diagnosing and predicting susceptibility to pouchitis after IPAA by detecting the presence or absence of pANCA and/or Cbir1 Flagellin expression.
US08486638B2	Method for fast detection and identification of micro-organisms The present invention relates to a specific method accomplishing fast and specific detection, identification and characterization of contaminating micro-organisms in various samples. A method has been developed based on the detection of species-specific and/or strain-specific nucleotide sequences that are uniquely identified and amplified and subsequently detected on a microarray using addressable identifier ZIP oligonucleotides. By using a two step screening process, the method of the present invention enables in first instance the fast screening of a multitude of samples for the presence or the absence of specific micro-organisms in such samples, while in a second screening step the positive results of the first step are further processed to identify and characterize the detected micro-organisms.
US08486635B2	Detecting and treating dementia This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents that can be used to increase PGRN polypeptide levels in mammals.
US08486632B2	Method for the in vitro diagnosis of bronchopulmonary carcinoma by detection of major alternative transcripts of the KLK8 gene encoding kallikrein 8 and use thereof for prognosticating survival A method for the in vitro diagnosis of bronchopulmonary carcinoma, in particular of non-small cell bronchial carcinoma, that includes a stage of detecting, in a biological sample derived from a patient suspected to be suffering from bronchopulmonary carcinoma, at least one of the major alternative transcripts of the KLK8 gene encoding kallikrein 8. This method is particularly useful for the survival prognostication of patients suffering from bronchopulmonary carcinoma.
US08486631B2	Quality control methods for the manufacture of polymer arrays Described are quality control methods and devices for the reproducible manufacturing and integrity monitoring of polymers on electrochemical synthesis and detection chips. The devices and methods allow for simultaneous manufacturing and synthesis of polymers.
US08486630B2	Methods for accurate sequence data and modified base position determination Disclosed herein are methods of determining the sequence and/or positions of modified bases in a nucleic acid sample present in a circular molecule with a nucleic acid insert of known sequence comprising obtaining sequence data of at least two insert-sample units. In some embodiments, the methods comprise obtaining sequence data using circular pair-locked molecules. In some embodiments, the methods comprise calculating scores of sequences of the nucleic acid inserts by comparing the sequences to the known sequence of the nucleic acid insert, and accepting or rejecting repeats of the sequence of the nucleic acid sample according to the scores of one or both of the sequences of the inserts immediately upstream or downstream of the repeats of the sequence of the nucleic acid sample.
US08486628B2	Method of normalized quantification of nucleic acids using anchor oligonucleotides and adapter oligonucleotides The present invention is related to normalized quantification of nucleic acids and to the normalization of quantities of nucleic acids in samples, e.g. mixtures of nucleic acids. The present invention relates to method for the normalization of the quantity of a nucleic acid to be quantified in a sample to the total quantity of nucleic acid in the sample; or to the total quantity of a specific class of nucleic acid in the sample.
US08486626B2	Methods of detecting cell-free miRNA in urine and blood Described are non-invasive methods of detecting in vivo cell death by measuring levels of ubiquitous and tissue specific miRNA. The method can be applied for detection of pathologies caused or accompanied by cell death, as well as for diagnosis of infectious disease, cytotoxic effects induced by different chemical or physical factors, and the presence of specific fetal abnormalities.
US08486625B2	Detection of nucleic acid reactions on bead arrays The present invention is directed to methods and compositions for the use of microsphere arrays to detect and quantify a number of nucleic acid reactions. The invention finds use in genotyping, i.e. the determination of the sequence of nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs). Similarly, the invention finds use in the detection and quantification of a nucleic acid target using a variety of amplification techniques, including both signal amplification and target amplification. The methods and compositions of the invention can be used in nucleic acid sequencing reactions as well. All applications can include the use of adapter sequences to allow for universal arrays.
US08486622B2	Genomic assay A method of detecting a nucleic acid sequence in a genomic sample, includes: providing the genomic sample containing a target nucleic acid sequence of a duplex nucleic acid; providing, a probe containing a probe nucleic acid sequence; providing a hybridization mixture containing the genomic sample, the probe, a hybridization promoting agent and labels; incubating the hybridization mixture; irradiating the incubated mixture with radiation effective to stimulate at least some of the labels to emit energy; and detecting from a fluorescent signal whether the probe perfectly matches the target nucleic acid sequence, wherein the detecting is completed within sixty minutes of the hybridization mixture providing, and the method is conducted without denaturing and without PCR amplifying the duplex nucleic acid. A kit for practicing the method includes the probe, the hybridization promoting agent, and labels.
US08486612B2	Methods of forming intermediate semiconductor device structures using spin-on, photopatternable, interlayer dielectric materials A cap material may be formed over a photopatternable material on a semiconductor substrate. The cap material absorbs or reflects radiation and protects the photopatternable material from a first wavelength of radiation used in patterning the photoresist layer. Upon exposure to a first wavelength of radiation, the photopatternable material may be converted into a silicon dioxide-based material. The silicon dioxide-based material may be selectively removed.
US08486610B2	Mask material conversion The dimensions of mask patterns, such as pitch-multiplied spacers, are controlled by controlled growth of features in the patterns after they are formed. To form a pattern of pitch-multiplied spacers, a pattern of mandrels is first formed overlying a semiconductor substrate. Spacers are then formed on sidewalls of the mandrels by depositing a blanket layer of material over the mandrels and preferentially removing spacer material from horizontal surfaces. The mandrels are then selectively removed, leaving behind a pattern of freestanding spacers. The spacers comprise a material, such as polysilicon and amorphous silicon, known to increase in size upon being oxidized. The spacers are oxidized to grow them to a desired width. After reaching the desired width, the spacers can be used as a mask to pattern underlying layers and the substrate. Advantageously, because the spacers are grown by oxidation, thinner blanket layers can be deposited over the mandrels, thereby allowing the deposition of more conformal blanket layers and widening the process window for spacer formation.
US08486607B2	Method of making a relief image A relief (or flexographic) printing precursor has first and second radiation-sensitive layers, or a plurality of radiation-sensitive layers. The first radiation-sensitive layer is sensitive to a first imaging radiation having a first λmax. The second radiation-sensitive layer is disposed on the first radiation-sensitive layer and is sensitive to a second imaging radiation having a second λmax that differs from the first λmax by at least 25 nm. An infrared radiation ablatable layer can be present and is opaque or insensitive to the first and second imaging radiations and contains an infrared radiation absorbing compound. These relief printing precursors can be used to prepare flexographic printing plates, cylinders, or sleeves where the ablatable layer is used to form an integral mask on the element. Use of the invention provides a relief image without any loss in the strength of the small dots and can be carried out using multiple irradiation steps using the same apparatus.
US08486606B2	Acrylate derivative, haloester derivative, polymer compound and photoresist composition An acrylate derivative represented by the following general formula (1): (in the formula, R1 represents a hydrogen atom, a methyl group or a trifluoromethyl group; each of R2, R3, R5, R7, R8, R9 and R10 independently represents a hydrogen atom, an alkyl group, a cycloalkyl group or an alkoxy group; each of R4 and R6 independently represents a hydrogen atom, an alkyl group, a cycloalkyl group or an alkoxy group, or R4 and R6 are bonded to each other to represent an alkylene group, —O— or —S—; n represents 0, 1 or 2; and W represents an alkylene group or a cycloalkylene group); an intermediate thereof; a method for producing the same; a polymer compound which is obtainable from polymerization of a raw material containing the foregoing acrylate derivative and which is excellent in solubility in an organic solvent used for the preparation of a photoresist composition; and a photoresist composition containing the polymer compound, an organic solvent and a photo acid generator and having excellent adhesion to substrate and less pattern collapse, are provided.
US08486605B2	Positive resist composition and method of forming resist pattern A positive resist composition including: a base material component (A) which exhibits increased solubility in an alkali developing solution under the action of acid; and an acid generator component (B) which generates acid upon exposure; dissolved in an organic solvent (S), wherein the base material component (A) includes a resin component (A1) having 4 types of specific structural units, and the organic solvent (S) includes from 60 to 99% by weight of an alcohol-based organic solvent (S1) and from 1 to 40% by weight of at least one organic solvent (S2) selected from the group consisting of propylene glycol monomethyl ether acetate, propylene glycol monomethyl ether and cyclohexanone.
US08486597B2	Toner, and method for producing the same A toner including an amorphous resin (R), a crystalline material (A) which is compatible with the amorphous resin (R) and has a melting point of 80° C. or lower, a resin (I) which is different from the amorphous resin (R), and a colorant, wherein the crystalline material (A) is capsulated by the resin (I) and the capsulated crystalline material (A) is present in the amorphous resin (R).
US08486595B2	Image bearing member, image forming apparatus, and process cartridge An image bearing member including an electroconductive substrate, a photosensitive layer overlying the electroconductive substrate, and a protection layer overlying the photosensitive layer, the photosensitive layer containing a diamine compound represented by the chemical structure 1, more of the diamine compound being disposed on the photosensitive layer side than the surface side relative to the midpoint in a depth direction of the protection layer: where X represents a substituted or non-substituted arylene group, or a compound represented by a chemical structure 2: where R represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an alkoxy group having 1 to 4 carbon atoms, where A1, A2, A3, and A4 independently represent an alkyl group having 1 to 4 carbon atoms, a substituted or non-substituted aryl group, or —CH2(CH2)mZ, where Z represents a substituted or non-substituted aryl group, a substituted or non-substituted cycloalkyl group, and a substituted or non-substituted heterocycloalkyl group, and m represents 0 or 1, and where B1 and B2 represent —CH2—, —CH2CH2—, —CH2—Ara—, —Ara—CH2—, —CH2CH2—Ara—, and —Ara—CH2CH2—, and Ara represents a substituted or non-substituted arylene group.
US08486594B2	P-terphenyl compound mixture and electrophotographic photoreceptors made by using the same An object of the invention is to provide: a p-terphenyl compound mixture useful as a charge-transporting agent which has improved solubility in organic solvents to thereby diminish a cracking phenomenon, which poses problems concerning photoreceptor characteristics, and can realize an electrophotographic photoreceptor having high sensitivity and high durability; and an electrophotographic photoreceptor employing the compound mixture. The invention relates to: a p-terphenyl compound mixture which includes two symmetric p-terphenyl compounds respectively represented by the following general formula (1) and general formula (2) and an asymmetric p-terphenyl compound represented by the following general formula (3) which has both a group of substituents of the compound represented by general formula (1) and a group of substituents of the compound represented by general formula (2); and an electrophotographic photoreceptor containing the compound mixture.
US08486588B2	Optically semitransmissive film, photomask blank and photomask, and method for designing optically semitransmissive film A photomask blank includes a transparent substrate and a film containing at least two layers having at least a first layer and a second layer formed on the transparent substrate. The first layer is made of a material containing one or more materials selected from the group Ta, Hf, Si, Cr, Ag, Au, Cu, Al, and Mo. The second layer is made of MoSiN, MoSiO, MoSiON, SiN, SiO, or SiON. A phase difference of the film containing at least two layers is from −30° to +30°.
US08486586B2	Laser irradiation device and method of fabricating organic light emitting display device using the same A laser irradiation device and a method of fabricating an organic light emitting display device (OLED) using the same are disclosed. The laser irradiation device includes: a laser source generating a laser beam; a mask disposed below the laser source and patterning the beam and a projection lens disposed below the mask and determining magnification of the laser beam through the mask, wherein the laser beam penetrating the mask has different doses in at least two regions. Thus, the laser irradiation device can maximize emission efficiency and enhance the quality of a transfer layer pattern when an organic layer of the OLED is formed using the laser irradiation device.
US08486585B2	Electrode assembly for a solid oxide fuel cell and method for making the same An electrode assembly for a solid oxide fuel cell, the electrode assembly including a porous ceramic oxide matrix and an array of fluid conduits. The porous ceramic oxide matrix includes a labyrinth of reinforcing walls interconnected to one another. Each of the fluid conduits is formed from the porous ceramic oxide matrix and has an external surface with a plurality of struts projecting outwardly therefrom and an internal surface defining a first passage for flowing a first fluid therethrough. The struts are configured to connect the fluid conduits to one another and the external surfaces and the struts define a second passage around the fluid conduits for flowing a second fluid therethrough.
US08486580B2	Integrated seal for high-temperature electrochemical device The present invention provides electrochemical device structures having integrated seals, and methods of fabricating them. According to various embodiments the structures include a thin, supported electrolyte film with the electrolyte sealed to the support. The perimeter of the support is self-sealed during fabrication. The perimeter can then be independently sealed to a manifold or other device, e.g., via an external seal. According to various embodiments, the external seal does not contact the electrolyte, thereby eliminating the restrictions on the sealing method and materials imposed by sealing against the electrolyte.
US08486578B2	Electrolyte membrane/electrode structure and fuel cell An electrolyte membrane/electrode structure constituting a fuel cell comprises a solid polymer electrolyte membrane, an anode side electrode and a cathode side electrode sandwiching the solid polymer electrolyte membrane. The anode side electrode is provided with an electrode catalyst layer and a gas diffusion layer abutting on one side of the solid polymer electrolyte membrane and exposing the outer circumference thereof in the shape of a frame, and the cathode side electrode is provided with an electrode catalyst layer and a gas diffusion layer abutting on the other side of the solid polymer electrolyte membrane. A reinforcing sheet member is arranged on the frame-shaped surface of the solid polymer electrolyte membrane projecting from the outer circumference of the gas diffusion layer.
US08486576B2	In-line height measurement system for planar fuel cell An in-line planar fuel cell height measurement system is mainly composed of a main stand, at least a top platform above a high temperature furnace, a displacement detection unit on the top platform with a central axis connecting to an extension rod that goes downward into the high temperature furnace and contacts the top surface of the cell stack inside the high temperature furnace, a displacement display unit connecting to the displacement detection unit through signal transmission cables, and a data processing unit connecting to the displacement display unit through signal transmission cables, so the displacement detection unit can sense the height change for the cell stack in the high temperature furnace during temperature rise and operation and send out a signal, which can be directly displayed by the displacement display unit and received by a data processing unit for further analysis and storage.
US08486575B2	Passive hydrogen vent for a fuel cell A fuel cell has a hydrogen flow path adapted to pass hydrogen into communication with an anode catalyst of an MEA. A coolant flow path is adapted to pass coolant through the fuel cell to cool the fuel cell. An enclosure encompasses at least a portion of the hydrogen flow path, the coolant flow path, or both. A hydrogen vent is adapted to vent hydrogen from the enclosure without reliance upon any electrical device. The hydrogen vent can prevent a frame front from passing into the enclosure and can be made of a porous material such as cellulose, plastic (for example, a foamed plastic) or metal (for example a sintered metal). A method of manufacturing a fuel cell includes passively venting hydrogen to maintain a hydrogen concentration level within the enclosure below about 4 percent. Additional enclosures with hydrogen vents may also be provided.
US08486565B2	Electrode, and lithium ion secondary battery, electric double layer capacitor and fuel cell using the same The present invention provides an electrode comprising a carbon material obtained from an azulmic acid and a current collector and/or a binder.
US08486562B2	Thin film electrochemical energy storage device with three-dimensional anodic structure A method for forming a battery from via thin-film deposition processes is disclosed. A mesoporous carbon material is deposited onto a surface of a conductive substrate that has high surface area, conductive micro-structures formed thereon. A porous, dielectric separator layer is then deposited on the layer of mesoporous carbon material to form a half cell of an energy storage device. The mesoporous carbon material is made up of CVD-deposited carbon fullerene “onions” and carbon nano-tubes, and has a high porosity capable of retaining lithium ions in concentrations useful for storing significant quantities of electrical energy. Embodiments of the invention further provide for the formation of an electrode having a high surface area conductive region that is useful in a battery structure. In one configuration the electrode has a high surface area conductive region comprising a porous dendritic structure that can be formed by electroplating, physical vapor deposition, chemical vapor deposition, thermal spraying, and/or electroless plating techniques.
US08486561B2	Electrochemical device and manufacturing method thereof An electrochemical device according to the present invention has an outer package including a metal film; a battery element enclosed in the outer package; resin layers provided at least inside a sealing region of the outer package; and a lead extending from the battery element through between the resin layers in the sealing region of the outer package to the outside of the outer package, and a shape of the lead in the sealing region includes front and back surfaces both consisting of curved surfaces. In the sealing region, a maximum thickness Z1 of the lead near a lateral center position of the lead and a thickness Z11 at a lateral end position of the lead satisfy the relation of Z11
US08486560B2	Battery pack thermal protection from heat sterilization An application for a battery pack that includes a set of walls made of sturdy material, power interface terminals and battery cells/electronics held within the walls. The battery cells are separated from the walls by a highly insulating material, thereby reducing the temperature that the battery cells reach during heat sterilization cycles performed on the battery pack after, for example, exposure of the battery pack to pathogens.
US08486555B2	Method for producing porous laminate and porous laminate A process for producing a porous laminate having many micropores interconnected in the thickness direction, which comprises: a step in which a laminate is produced which comprises at least three layers comprising an interlayer made of a thermoplastic resin having a hard segment and a soft segment and two nonporous outer layers made of a filler-containing resin and located as outer layers respectively on both sides of the interlayer; a step in which the laminate obtained is impregnated with a supercritical or subcritical fluid and this state is relieved to vaporize the fluid and thereby make the interlayer porous; and a step in which the two nonporous outer layers located respectively on both sides are made porous by stretching.
US08486553B2	Battery pack A battery pack including a battery module including at least one battery cell; and a spray unit above the battery module for spraying an insulation fluid onto the battery module.
US08486551B2	Fuel cell unit, fuel cell unit array, fuel cell module and fuel cell system The present invention provides a fuel cell unit, fuel cell unit array, fuel cell module and fuel cell system that can achieve a reduction in size and costs. The fuel cell unit of the present invention has a PIN structure comprising a fuel electrode (11) formed of a p-type semiconductor, an oxygen electrode (13) formed of an n-type semiconductor, and an interlayer (12) formed of an intrinsic semiconductor lying between the fuel electrode (11) and the oxygen electrode (13); wherein the fuel electrode (11) and the oxygen electrode (13) are porous and have fluid permeability; a metal-based catalyst layer is formed on the inner surfaces of pores in the porous portion; the interlayer (12) is porous so that hydrogen ions generated at the fuel electrode (11) can pass therethrough, but electrons are blocked; hydrogen-containing fuel is supplied to the surface of the fuel electrode (11) and an oxygen-containing oxidizing fluid is supplied to the surface of the oxygen electrode (13); and connecting terminals each electrically connected to the fuel electrode (11) and the oxygen electrode (13).
US08486543B2	Light-emitting element, light-emitting device, electronic device, and lighting device Objects of the present invention are to provide: a light-emitting element having a long lifetime and good emission efficiency and drive voltage. One embodiment of the invention is a light-emitting element including, between an anode and a cathode, at least a stack structure in which a first layer, a second layer, and a light-emitting layer are provided in order from the anode side. The first layer includes a first organic compound and an electron-accepting compound. The second layer includes a second organic compound having a HOMO level differing from the HOMO level of the first organic compound by from −0.2 eV to +0.2 eV. The light-emitting layer includes a third organic compound having a HOMO level differing from the HOMO level of the second organic compound by from −0.2 eV to +0.2 eV and a light-emitting substance having a hole-trapping property with respect to the third organic compound.
US08486539B2	Coating compositions and coatings produced from them with high scratch resistance, weathering stability, and good optical properties The invention relates to coating compositions comprising (a) at least one hydroxyl-containing compound (A), (b) at least one saturated compound (B) having free and/or blocked isocyanate groups and containing at least in part hydrolyzable silane groups, and (c) at least one catalyst (D) for the crosslinking of silane groups, wherein the coating composition comprises as hydroxyl-containing compound (A) at least one hyperbranched, dendritic hydroxy-functional polyester in which on average at least one hydroxyl function of the polyester is esterified with at least one acid selected from the group of the isomeric C8 to C9 monocarboxylic acids. The present invention also provides a multistage coating method using these coating compositions, and also the use of the coating compositions as clearcoat material for producing multicoat effect and/or color paint systems, and use of the coating method for automotive OEM finishing and automotive refinish.
US08486538B2	Electrodepositable coating composition comprising silane and yttrium An electrodepositable coating composition comprising (i) a film-forming polymer, (ii) a corrosion inhibitor, and (iii) a silane that does not contain an ethylenically unsaturated double bond.
US08486536B2	Glass material for press molding, method for manufacturing optical glass element using same, and optical glass element Disclosed is a glass material for press forming providing an optical element having a sufficient optical performance without surface cracks, cloudiness, scratches, and the like even when the glass material contains a highly reactive component. Also disclosed are an optical element having a sufficient optical performance without surface cracks, cloudiness, scratches, and the like and a method for manufacturing the same. Specifically disclosed is a glass material for press forming which comprises a core portion composed of multicomponent optical glass and a surface glass layer covering at least a region serving as an optical functional surface of the core portion. The surface glass layer contains more than 90 mass % of SiO2, and the thickness of the layer is less than five nanometers. Also specifically disclosed is a method for manufacturing a glass optical element by heating the glass material and by press forming the softened glass material using a forming die. Yet also specifically disclosed is a press formed glass optical element having a core portion composed of multicomponent optical glass and a surface glass layer covering at least an optical functional surface of the core portion. The surface glass layer contains more than 90 mass % of SiO2, and the thickness of the layer is less than five nanometers.
US08486534B2	Surface-modified polymer films Surface-modified polymer films for coating are provided, wherein the surface is modified by covalent binding of nano- or micro-particles comprising a photoreactive species. The surface of the polymer film, e.g. a parylene film, may be modified by covalent binding of nano- or micro-particles of a polymer, e.g. a conductive bifunctional polymer further comprising a chemically reactive functional group, or of a hybrid organic-inorganic oxide, e.g., silica, network comprising a photoreactive species. Further provided are: (i) polymerizable monomers, the conductive bifunctional polymers obtained therefrom; (ii) a hybrid photoreactive organic-inorganic oxide network; and (iii) micro- or nano-particles made from (i) or (ii).
US08486530B2	Method for reducing volatile organic compounds in composite resin particles, and composite resin particles A method of reducing a volatile organic compound of composite resin particles comprising the step of: blowing a gas from a bottom part of a container in order to fluidize composite resin particles containing a polyolefin-based resin and a polystyrene-based resin in the container until an amount of volatile organic compounds contained in the whole composite resin particles becomes 50 ppm or less, wherein the gas has a temperature of (T−40) to (T−10)° C. when a softening temperature of the composite resin particles is defined as T° C.
US08486529B2	Fine metal carbide particles and methods of manufacturing the same There is provided fine metal carbide particles which do not require pulverization of an initial material, a reaction intermediate and a product that causes the contamination with metallic impurities, which can promote a carbonization reaction uniformly at a lower temperature than in the past, and which can be manufactured at a low cost; and a method of manufacturing the same. The fine metal carbide particles are prepared by heat-treating, in a nonoxidizing atmosphere or a vacuum atmosphere, a solid obtained by drying an aqueous metal complex solution containing a water-soluble metal compound, and a low-molecular-weight water-soluble organic compound having one or more functional group(s) selected from the group consisting of amino group, hydroxyl group and carboxyl group, and having at least one of oxygen and nitrogen as heteroatom(s). In the fine metal carbide particles, the average particle diameter is 100 nm or less, the content of iron as impurities is 100 ppm or less, and the ratio of the total carbon amount is within ±0.3 wt % around a theoretical ratio of the total carbon amount calculated from the composition of the metal carbide.
US08486522B2	Multi-layer composite materials comprising a foam layer, corresponding method of production and use thereof Multi-layer composite materials comprising a foam layer, corresponding method of production and use thereof.Multilayered composite materials comprising as components: (A) a foam layer where the foam is selected from polystyrene foams, polyurethane foams, polyester foams, butadiene-styrene block copolymer foams, natural sponges and amino resin foams, (B) optionally at least one bonding layer and (C) a polyurethane layer.
US08486516B2	Plastic coated composite building boards and method of making same Disclosed are composite building boards and associated manufacturing methods. The composite boards may include, for example, one or more slurry layers with embedded fibrous mats. An exterior plastic coating is mechanically adhered to the underlying slurry layer. The plastic layer chemically bonds and cross-links with polymer additives within the slurry layer. The result is an integrated polymer matrix with greatly improved durability and surface strength.
US08486510B2	Integral frame structures A method allows production of integral frame structures having at least three structural portions separated circumferentially about a central axis and at least one hollow region radially inward thereof. Each of plural mold sections fits between structural potions, and a portion of the mold interior includes a wedge shaped portion which allows the mold sections to slide past the structural portions when molding is complete.
US08486503B2	Surgical tape A surgical tape (1) includes a carrier (2, 3), on one side coated with an adhesive (4) and including a layer of non-woven (3). A layer of plastic film (2) is laminated to the layer of non-woven and the surgical tape (1) is tearable in a cross direction relative its longitudinal direction and liquid impermeable.
US08486499B2	Ink jet recording medium An ink jet recording medium including a substrate and two or more ink receiving layers provided on the substrate, wherein a first ink receiving layer that is an outermost ink receiving layer of the two or more ink receiving layers and a second ink receiving layer adjacent to the first ink receiving layer contain an alumina pigment, polyvinyl alcohol and boric acid. The first ink receiving layer contains polyvinyl alcohol in an amount of 7.0-10.5% by mass or less based on the alumina pigment and contains boric acid in an amount of 1.1-1.4% by mass or less based on the alumina pigment. The second ink receiving layer contains polyvinyl alcohol in an amount of 10.5-17.0% by mass or less based on the alumina pigment and contains boric acid in an amount of 1.5-2.5% by mass or less based on the alumina pigment.
US08486497B2	Liquid crystal compound, and liquid crystal display An embodiment of the invention provides a liquid crystal compound having the following formula: wherein A1, A2, and A3 are independently hydrogen, halogen, cyano, thiocyanato, or —OCF3; R1 is hydrogen, halogen, C1-C12 alkyl, C1-C12 alkoxy, C1-C12 haloalkyl, C2-C12 alkenyl, or C2-C12 alkynyl; R2 is hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, cyano, or —OCF3; and Z is —O—, —CH2O—, —C(O)O—, —OCO—, —C(O)NH—, —CH═CH—, or —C≡C—. In another embodiment, a liquid crystal display including the liquid crystal compound is also provided.
US08486491B2	Process for producing surface conditioned aluminum castings A process for producing surface conditioned aluminum castings, comprising a step of applying to aluminum castings an alkaline surface conditioning liquid containing at least one organic builder and/or one chelating agent, wherein the alkaline surface conditioning liquid used in the step has a surface conditioning activity (CD; mol/l) in the range of 0.05≦CD≦2.3 and a coefficient of gloss (CE; g/mol) in the range of 2.8≦CE≦90.
US08486487B2	Gas barrier film, gas barrier film manufacturing method, resin substrate for organic electroluminescent device using the aforesaid gas barrier film, and organic electroluminescent device using the aforementioned gas barrier film A gas barrier film comprising a resin substrate provided thereon at least one layer of a ceramic film, wherein the density ratio Y (=ρf/ρb) satisfies 1≧Y≧0.95 and the ceramic film has a residual stress being a compression stress of 0.01 MPa or more and 100 Mpa or less, wherein ρf is the density of the ceramic film and ρb is the density of a comparative ceramic film being formed by thermal oxidation or thermal nitridation of a metal as a mother material of the ceramic film so as to being the same composition ratio of the ceramic film.
US08486485B2	Method of dispensing imprintable medium An imprintable medium dispenser includes a chamber, a nozzle, and an actuator connected to the chamber and configured to be actuated and thereby generate a pressure wave within the chamber such that imprintable medium is dispensed from the nozzle. The imprintable medium dispenser is provided with a control circuit which includes a monitoring apparatus configured to receive a transient oscillation signal generated when the actuator is actuated, and to monitor the operation of the imprintable medium dispenser by monitoring the transient oscillation signal.
US08486482B2	Methods to improve adhesion of polymer coatings over stents Methods are disclosed to improved adhesion of polymer coatings over polymer surfaces of stents which include plasma treatment, applying an adhesion promoting layer, surface treatments with solvents, and mechanical roughening techniques.
US08486480B2	Controlled acidification of food products using lactic- or glycolic acid oligomers/derivatives This invention relates to the controlled acidification of food products, like dairy products, meat etc. By acidification, food products are protected against harmful microbiological cultures and food can get a certain texture, e.g. the coagulation of dairy products or the drying and texture formation of dried sausages. The invention comprises a new method of acidifying food products in a controlled way. Using lactic- or glycolic acid oligomer/derivatives and salts or derivatives thereof achieve this controlled acidification.
US08486479B2	Shortening compositions and methods of making and using the same Described herein are shortening compositions having reduced levels of saturated and trans fats. The compositions comprise cellulose fibers, a hard fat and a liquid oil. Also provided are methods of preparing such compositions and use thereof.
US08486478B2	Structured lipid compositions Lipid compositions are provided exhibiting the functionality of a typical shortening or filler fat, but are achieved with reduced and essentially zero trans-unsaturated fatty acids and that deliver reduced caloric content. By one approach, the functional lipid compositions include a blend of a matrix building ingredient, which is preferably a structured glycerol ester, and an edible liquid oil diluent in ratios such that the lipid composition exhibits the functionality of the traditional shortening or filler fat.
US08486476B2	Yogurt-cheese compositions Technique for making a Low-Fat Yogurt-Cheese Composition, including: providing a composition including a milkfat fluid; combining yogurt with the composition including a milkfat fluid to form a composition including yogurt and a milkfat fluid; combining milk protein with the composition including yogurt and a milkfat fluid; and forming a blend including the milk protein and the composition including yogurt and a milkfat fluid. Low-Fat Yogurt-Cheese Composition, including: cream cheese at a concentration within a range of between about 75% by weight and about 15% by weight; yogurt at a concentration within a range of between about 40% by weight and about 10% by weight; and milk protein at a concentration within a range of between about 45% by weight and about 15% by weight.
US08486475B2	Rice flour compositions Rice flour compositions having a Peak Viscosity of from about 4 RVU to about 130 RVU. In one embodiment, the rice flour compositions have a Final Viscosity of from about 4 RVU to about 220 RVU. Preferably, the compositions have a WAI of from about 2.6 to about 9. In a preferred embodiment, the Peak Viscosity of the rice flour compositions is ≦about 55(WAI)-145. The compositions can be used to produce food products such as fabricated sheeted snacks, extruded products, sauces, coatings for fried foods, dog foods, dog biscuits, baby foods and breads. The preferred doughs formed from the inventive rice flour composition are sheetable and elastic, and fabricated snacks made from the doughs have the desired taste and texture characteristics. A dry blend for a preferred fabricated snack comprises from about 2% to about 100%, preferably from about 3% to about 33%, most preferably from about 4% to about 17%, of the rice flour composition.
US08486470B2	Ready-to-eat food product A ready-to-eat food product includes a fruit core and a barrier coating covering the fruit core. The barrier coating can be a solid or semi-solid up to substantially 41 degrees Celsius. The ready-to-eat food product further includes an outer protective coating distributed around the barrier coating. The outer protective coating can include a plurality of dry particles separating an outer surface of the outer protective coating and an outer surface of the barrier coating.
US08486467B1	Dermal filler and method of using same Polyglutamic acid (PGA) formulations are provided for use as a dermal filler. Also provided are methods of use of such formulations for treatment of cosmetic defects.
US08486463B1	Cosmetic composition comprising aloe vera and caprylyl salicylic acid and method of making A cosmetic composition in the form of an emulsion and process for preparing the cosmetic composition using cold-processing are provided. The cosmetic composition includes at least one hydrating agent including Aloe Barbadensis Leaf Juice, the hydrating agent at a concentration, by weight, of about 10% to about 70%, based upon weight of the composition. The composition includes at least one viscosity modifier, at least one mattifer, at least one humectant, at least one thickener, and caprylyl salicylic acid. The caprylyl salicylic acid is at a concentration, by weight, of about 0.01% to about 0.5% based upon weight of the composition. The cosmetic composition has a hydration index greater than water.
US08486462B2	Glycoside having 4-methylergost-7-en-3-ol skeleton and hyperglycemia improving agent 3-O-β-D-Glucopyranosyl-4-methylergost-7-en-3-ol or a composition containing 0.001% by mass or more of the aforementioned compound, which is an extract of a plant of the family Liliaceae containing the compound or a fraction thereof, is used as an active ingredient of a hyperglycemia improving agent.
US08486460B2	Herbal composition for lowering likelihood of stroke and methods for healing stroke patients Compositions and methods are provided for lowering blood pressure, lowering blood sugar, lowering cholesterol, prevent stroke, removing age spots, curing stroke, or enlarging blood vessels to remove the toxins from the blood. In one embodiment, the composition comprises the herbal extracts of liquorice root, self-heal, mulberry leaves, chrysanthemum, ginkgo nuts, mangosteen, maltose and dextrin. The composition is used as a nutraceutical treatment to lower likelihood of stroke.
US08486459B2	Bulbine frutescens extract A method of producing a Bulbine frutescens extract in a stable form by treating juice expressed from the leaves of the Bulbine frutescens plant with hydrogen peroxide, removing the remaining hydrogen peroxide and stabilizing the extract using a suitable stabilizer. The Bulbine frutescens extract is used in the therapeutic or cosmetic fields and has an especially good effect on diseases of the skin and mucous membranes, in particular infections or inflammations such as fungal diseases, in prevention and/or curing injuries to the skin and mucous membranes, in particular burn wounds, as a disinfectant, as an agent to improve the immune defense, for body care, oral care, as an antiperspirants and as an antiaging product. The effect is to some extent far superior to that of commercial products, and there is no damage to the natural microflora of the skin and mucous membranes but instead they remain intact. Furthermore, the appearance of the skin is greatly improved.
US08486454B2	Method of attenuating neurogenic pain The present invention provides a method of attenuating the formation or reducing the severity of neurogenic pain in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic pain.
US08486445B2	Self-microemulsifying mitotane composition The invention relates to a self-microemulsifying drug delivery system (“SMEDDS”) of mitotane, with enhanced bioavailability. More particularly the invention provides a mitotane oily formulation comprising propylene glycol monocaprylate (10 to 30% w/w), propylene glycol dicaprate (20 to 60% w/w) and polyoxyethylenesorbitanne monooleate (10 to 30% w/w).
US08486442B2	External patch containing estrogen and/or progestogen An external patch capable of stable prolonged release and transdermal absorption of active ingredient hormones (estrogens and/or progestogens) contained in a pressure sensitive adhesive layer, which external patch ensures low irritation on the skin. In particular, an external patch comprising a support and, superimposed thereon, a pressure sensitive adhesive layer, characterized in that the pressure sensitive adhesive layer comprises, as indispensable components, 5 to 50 wt. % of styrene/isoprene/styrene block copolymer, 20 to 70 wt. % of tackifier resin, 10 to 60 wt. % of softener and 1 to 20 wt. % of polyvinylpyrrolidone and contains, as an active ingredient, estrogen and/or progestogen.
US08486441B2	Methods compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue A composition of matter including at least one stinging capsule comprising a therapeutic or cosmetic agent is described.
US08486438B2	Methods for progenitor cell recruitment and isolation The invention relates to the use of one or more growth factors in a drug delivery system, optionally with an external mesh housing, to recruit and optionally harvest progenitor cells. These cells include those that normally reside in the bone marrow.
US08486436B2	Articular joint implant Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
US08486429B2	Storage stable formulation and a process for its preparation The present invention is directed to a storage stable insecticidal composition comprising one or more Chloronicotynyle compound, in an amount ranging from 0.1 to 5% by weight of the composition, one or more compounds falling within the group of Organophosphorus compounds in an amount ranging from 30 to 75% by weight of the composition and 69.9 to 20% by weight of conventional agriculturally acceptable carrier(s) and excepient(s) along with the process for obtaining the storage stable composition. At least one of the active ingredients is provided with a coating of a water soluble polymer.
US08486428B2	Compositions and methods for making and using acyclic N-halamine-based biocidal polymeric materials and articles The present invention includes methods and compositions for providing rechargeable aliphatic N-halamine polymers, monomers, copolymers additives and coatings. The rechargeable aliphatic N-halamine includes an aliphatic N-halamine compound exchangeable associated with one or more halides.
US08486427B2	Wipe for use with a germicidal solution An antimicrobial wipe that contains a polymer coating having a synergistic combination of ingredients for providing controlled release of an antimicrobial agent and also good antimicrobial efficacy is provided. One such ingredient is a high molecular weight polyamideamine release agent. Due to the polycationic nature of the release agent, it is able to adhere to the wipe, which is generally formed from fibers having a negative surface charge (e.g., cellulosic fibers). In this manner, the release agent can occupy binding sites on the wipe to inhibit the antimicrobial agent from adhering thereto, thus allowing it to be expressed in the germicidal solution to kill microbes on the desired surface. The adherence of the release agent to the wipe is even further enhanced by crosslinking the polyamideamine to increase its molecular weight, thereby enabling it to form a structural network that physically adheres to the wipe and that blocks the antimicrobial agent from binding thereto. Furthermore, the polyamideamine is amidated so that it contains secondary and/or tertiary amides. A cell permeabilizer is also employed in the polymer coating to enhance the efficacy of the antimicrobial agent during use. More particularly, polycationic materials are particularly useful in permeabilizing the outer cell membrane without adversely impacting the ability of the polyamideamine to release the antimicrobial agent within the wipe.
US08486426B2	Methods and compositions for treatment of dermal conditions The present invention comprises methods and compositions for the treatment of pathological conditions of the dermis and dermal structures of animals and humans. In particular, the present invention comprises the use of topical delivery vehicles, including hydrogels, which incorporate active agents such as organic acids, for the treatment of dermal conditions.
US08486424B1	Method of preparing a skin treatment composition One embodiment includes a method including boiling unsalted butter over low heat until it appears golden to form purified butter; cooling the purified butter by removing it from the heat; straining or filtering the purified butter; refrigerating the purified butter for at least 24 hours; thoroughly blending together the elements of an organic carrier medium, wherein the organic carrier medium comprises the purified butter, olive oil, and honey; adding distilled water to the blended organic carrier medium; mixing the distilled water and the blended organic carrier medium at high speed; and adding at least one of sodium acid pyrophosphate, cornstarch, bismuth subnitrate, salicylic acid, or alkali metal salicylates, and mixing.
US08486422B2	Methods of activating clostridial toxins The specification discloses modified Clostridial toxins comprising an exogenous Clostridial toxin di-chain loop protease cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins; method of producing such modified Clostridial toxins, method of activating such modified Clostridial toxins and methods of activating recombinantly-expressed Clostridial toxins.
US08486421B2	Antigen-norovirus P-domain monomers and dimers, antigen-norovirus P-particle molecules, and methods for their making and use A substituted Norovirus capsid protein monomer, having only the P-domain and called an antigen-Norovirus P-domain monomer, includes a foreign antigen inserted into one or more of three surface loops present on each P-domain monomer by molecular cloning. The antigen-P-domain monomer can assemble spontaneously into an octahedral form, called an antigen-Norovirus P-particle, that is composed of 24 copies of the antigen-P-domain monomer. Each substituted P-domain monomer will contain one to three copies of the foreign antigen, for a total of 24-72 antigen copies on each antigen-P-particle. The antigen-P-particle is useful in methods for diagnosing, immunizing and treating individuals infected with a foreign virus, for example Rotavirus, and can serve as a carrier for presentation of foreign antigens for development of novel vaccines against many infectious and non-infectious diseases. The substituted Norovirus P-particles can be readily produced in E. coli and yeast, are highly stable and tolerate a wide range of physio-chemical conditions. A modified Norovirus P-domain monomer includes one or more restriction recognition sites inserted within one or more of the three loops of the P-domain monomers, to provide user-friendly cloning cassettes for conveniently inserting candidate foreign antigens into the surface loops. The P-particle-VP8 chimeras may also serve as a dual vaccine against both rotavirus and norovirus.
US08486420B2	Live virus vaccines The present invention provides novel self-replicating and self-propagating chimeric viral vectors and chimeric virus particles comprising a modified genome of a carrier RNA virus packaged within structural proteins of a second virus. Also provided are pharmaceutical formulations comprising the chimeric viral vectors and virus particles and methods of inducing an immune response by administration of the same to a subject.
US08486419B2	Attenuated live vaccine Disclosed is an attenuated flavivirus live vaccine comprising a flavivirus mutant, characterized in that the flavivirus mutant has a deletion in the capsid protein of at least more than 4 successive amino acids, wherein the carboxy-terminal hydrophobic region is not affected by the deletion.
US08486406B2	Monoclonal antibodies as a medicament for the therapeutic and/or prophylactic treatment of swine-origin influenza A (H1N1) virus (S-OIV) infections The use of monoclonal antibodies Fab28 and Fab49 for the prophylactic or therapeutic treatment of swine-origin influenza A (H1N1) virus (S-OIV) infections is described, the which virus is responsible for the influenza syndrome commonly known as “swine flu”. Moreover, the use of the above-mentioned antibodies for selecting potential vaccines for active immunization against S-OIV is described.
US08486403B2	Method of promoting bone growth by an anti-activin A antibody In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density.
US08486399B2	Methods and compositions for increasing arylsulfatase A activity in the CNS Provided herein are methods and compositions for treating a subject suffering from a deficiency in arylsulfatase A in the CNS. The methods include systemic administration of a bifunctional fusion antibody comprising an antibody to a human insulin receptor and an arylsulfatase A.
US08486395B2	Anti-CD19 antibodies The present invention provides humanized, chimeric and human anti-CD19 antibodies, anti-CD19 antibody fusion proteins, and fragments thereof that bind to a human B cell marker. Such antibodies, fusion proteins and fragments thereof are useful for the treatment and diagnosis of various B-cell disorders, including B-cell malignancies and autoimmune diseases. In more particular embodiments, the humanized anti-CD19 antibodies may comprise one or more framework region amino acid substitutions designed to improve protein stability, antibody binding and/or expression levels. In a particularly preferred embodiment, the substitutions comprise a Ser91Phe substitution in the hA19 VH sequence.
US08486392B2	Methods and compositions for diagnosing and treating diseases Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.
US08486391B2	Cancer treatment kits using antibodies to aminophospholipids Disclosed are the surprising discoveries that aminophospholipids, such as phosphatidylserine and phosphatidylethanolamine, are stable and specific markers accessible on the luminal surface of tumor blood vessels, and that the administration of an anti-aminophospholipid antibody alone is sufficient to induce thrombosis, tumor necrosis and tumor regression in vivo. This invention therefore provides anti-aminophospholipid antibody-based methods and compositions for use in the specific destruction of tumor blood vessels and in the treatment of solid tumors. Although various antibody conjugates and combinations are thus provided, the use of naked, or unconjugated, anti-phosphatidylserine antibodies is a particularly important aspect of the invention, due to simplicity and effectiveness of the approach.
US08486386B2	Modified two-component gelation systems, methods of use and methods of manufacture Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and a substance having at least one cell adhesion site combined in a first buffer at a pH of approximately 6.5. A second component can include a second buffer in a pH of between about 7.5 and 9.0. A second functionalized polymer can be included in the first or second component. In some embodiments, the composition can include at least one cell type and/or at least one growth factor. In some embodiments, the composition(s) of the present invention can be delivered by a dual bore injection device to a treatment area, such as a post-myocardial infarct region.
US08486384B2	Lipidized interferon and methods of treating viral hepatitis The present invention is directed to methods and compositions useful in increasing in mammals the absorption and retention of polypeptides. The invention provides lipid-conjugated interferon having increased liver uptake and increased plasma half-life.
US08486381B2	Methods of modulating intestinal fluid balance The present invention relates to methods for treating intestinal fluid balance disorders and modulating intestinal fluid secretion and absorption using calcimimetics and calcilytics.
US08486380B2	Enzymatic peracid generation formulation Disclosed herein are multi-component formulations for enzymatically producing aqueous solutions of peroxycarboxylic acids suitable for use in, e.g., disinfectant and/or bleaching applications. The multi-component peroxycarboxylic acid formulations comprise at least one carbohydrate esterase family 7 enzyme having perhydrolytic activity.
US08486377B1	Beeswax and jojoba wax emulsion A composition of matter and a method are disclosed including mixing pieces of solid beeswax and liquid jojoba wax at a predetermined temperature within a predetermined range of temperatures, filtering the mixture, and cooling the mixture to form a colloidal gel.
US08486375B2	Foamable compositions The present invention is related to a foamable composition of matter comprising iodine, water, a foam adjuvant, a surface-active agent and a gelling agent. This foamable composition, which may be provided in a propellant free foaming device, or alternatively may further comprise a propellant, evolves into foam, which is effective in the topical treatment and prevention of various skin disorders.
US08486372B2	Cyclic azapeptides as integrin markers and methods of using The present application is directed to radiolabeled cyclic polyazapeptides, pharmaceutical compositions comprising radiolabeled cyclic polyazapeptides, and methods of using the radiolabeled cyclic polyazapeptides. Such polyazapeptides can be used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
US08486371B2	Quantitative two-photon flow cytometry A method and apparatus of multi-dye analysis of particles using flow cytometer. The method includes dying particles to be detected using two or more dyes; urging the particles through a capillary in a non-uniform flow; exciting a first of the particles within the capillary using a multiphoton excitation laser beam causing the two or more dyes each to fluoresce thereby producing a first output signal and a second output signal respectively; and detecting the first output signal and the second output signal. A second of the particles within the capillary being excited using the multiphoton excitation laser beam causing the two or more dyes each to fluoresce thereby producing a third output signal and a forth output signal respectively. The method finally includes comparing a ratio of the first output signal and the second output signal to a ratio of the third output signal and the forth output signal to detect a desired change in the particles.
US08486370B2	Heterocyclic ligands for integrin imaging and therapy The present invention provides α4β1 integrin ligands that display high binding affinity, specificity, and stability. The ligands comprise a peptide having n independently selected amino acids, wherein at least one amino acid is an unnatural amino acid or a D-amino acid, and wherein n is an integer of from 3 to 20. Methods are provided for administering the ligands for treating cancer, inflammatory diseases, and autoimmune diseases. Also provided are methods for administering the ligands for imaging a tumor, organ, or tissue in a subject.
US08486369B2	Introduction of mesoporosity in low Si/Al zeolites Compositions and methods for preparing mesoporous materials from low Si/Al ratio zeolites. Such compositions can be prepared by acid wash and/or isomorphic substitution pretreatment of low Si/Al ratio zeolites prior to introduction of mesoporosity.
US08486367B2	Method and device for generating hydrogen The invention relates to a method and a device for generating hydrogen (5), wherein an input (1) comprising carbon is fed longitudinally through a tube-shaped reaction chamber (Z), together with water steam (2), and is thereby converted by steam reforming, and hydrogen (4) formed during steam reforming is continuously drawn off out of the reaction chamber (Z) through a separating wall (T), said wall being selectively hydrogen-permeable at least in segments, and at a pressure less than the pressure in the reaction chamber (Z) and greater than the ambient pressure, having greater purity than product (5), characterized in that a separating wall (T) is used, the selectively hydrogen-permeability segments thereof being disposed such that a hydrogen partial pressure drop exists over the entire surface of each of such segments between the reaction chamber side and the hydrogen extraction side (W).
US08486363B2	Production of graphenic carbon particles utilizing hydrocarbon precursor materials A method is disclosed for making graphenic carbon particles. The method includes introducing a hydrocarbon precursor material capable of forming a two-carbon-fragment species into a thermal zone, heating the hydrocarbon precursor material in the thermal zone to form the graphenic carbon particles from the hydrocarbon precursor material, and collecting the graphenic carbon particles. Apparatus for performing such a method, and graphenic particles produced by the method, are also disclosed.
US08486362B2	Redispersible agglomerate of fine carbon fibers and method for producing thereof The disclosed is a redispersible agglomerate of fine carbon fibers, which is obtained by adding the fine carbon fibers and a dispersing agent which shows solid state at least at ordinary temperature (20±10° C.) into an aqueous dispersion medium, and then removing the dispersion medium from a dispersion system where the carbon fibers are isolated individually and dispersed in the dispersion medium; and in which the carbon fibers are got together and solidified in the agglomerate while each carbon fiber maintains its isolated dispersibility; wherein the carbon content is in the range of 0.01-99.5% by weight, the dispersing agent content is in the range of 0.1-99.5% by weight, and the moisture content is in the range of less than. 10% by weight, based on the total weight of the agglomerate; and wherein the dispersing agent is one member selected from the group consisting of (1) surfactants capable of forming spheroidal, cylindrical, or tabular micelles of 5-2000 nm in diameter in an aqueous solution; (2) water-soluble high polymers having a weight average molecular weight in the range of 10,000-50,000,000; and (3) a combination of cyclodextrin and fullerene. This redispersible agglomerate of fine carbon fibers has a good handling property and would form a dispersed state of individually isolated carbon fibers when it is added in any of various dispersion media.
US08486359B2	Ammonium recovery from waste water using CO2 acidified absorption water The processes are utilized to recover ammonium from waste water using CO2 acidified absorption water. The process is particularly suited for utilization of cellular matter and a CO2 rich tail gas from a syngas fermentation process and derives significant benefit from the recovery of ammonium bicarbonate and ammonium carbonate. Ammonia and ammonium are recovered from the treatment of the syngas as an ammonium rich solution, at least a portion of which is recycled to the fermentation zone to aid in the production of liquid products. A carbon dioxide rich gas produced by fermentation is used to capture the ammonia and ammonium, forming the ammonium rich solution.
US08486347B2	Carrier-enclosed transformable container, carrier-enclosed transformable container processing apparatus, and carrier-enclosed transformable container processing method Provided are a carrier-enclosed transformable container, a carrier-enclosed transformable container processing apparatus, and a carrier-enclosed transformable container processing method about which a carrier to which various substances such as biogenic substances are bonded or bondable is held in a transformable container as the container to be in a substantially stationary state, thereby making it possible to make the handling of the carrier, measurement, and other treatments effective, speedy, and easy. The container is formed to have: a containing part which can contain liquid and gas at its inside surrounded by a wall face, a part of this wall face having a transformable wall face capable of undergoing a predetermined transformation without changing the entire internal surface area of the wall face substantially; an orifice part which is connected to the containing part and can undergo the inflow and outflow of a liquid sucked and discharged by the expansion and contraction of the inside by the transformation of the transformable wall face, respectively; and a carrier to which a predetermined substance enclosed in the containing part to be in a substantially stationary state is bonded or bondable.
US08486346B2	Gas scrubber for automated clinical analyzer A device and method for extending the useful life of a bulk liquid used in an automated clinical analyzer. Air from the atmosphere surrounding the automated clinical analyzer that displaces the bulk liquid consumed from a container is routed through a gas scrubber in order to remove or at least reduce the quantity of at least one contaminant present in that air. The gas scrubber is positioned between the bulk liquid in the container and the atmosphere surrounding the container. The gas scrubber contains a reagent that is capable of reacting with a contaminant in the atmosphere, whereby a required characteristic(s) of the bulk liquid does (do) not change excessively prior to the date that the bulk liquid is consumed. For example, if the contaminant is carbon dioxide, and the required characteristic of the bulk liquid is the level of pH of the bulk liquid, the reagent in the gas scrubber prevents the level of pH of the bulk liquid from changing excessively prior to the date that the bulk liquid is consumed.
US08486345B1	Mobile sanitizer unit A mobile sanitizer unit for thoroughly sanitizing objects through the use of evenly distributed heat in a mobile trailer. The mobile sanitizer unit generally includes an enclosed chamber positioned upon a trailer vehicle frame for sanitizing objects (e.g. furniture, mattresses, fabric, etc.) within. The chamber includes a heater with that is separated from the contained objects to prevent overheating a specific area of the objects. The heat is circulated via one or more circulation fans. A floor passageway may also be defined for circulating the heated air underneath the objects. A plurality of temperature sensors are used to record the internal core temperature of the objects along with the ambient temperature within the chamber. A separately accessible control room may also be located upon the vehicle frame and include a controller therein for receiving data from the temperature sensors and for controlling the heater and the circulation fans.
US08486342B2	Syringe, system and method for delivering oxygen-ozone In accordance with at least one exemplary embodiment, a syringe, method and system for delivering a therapeutic amount of ozone are disclosed. An exemplary syringe can have a gas chamber and one or more electrodes. A portion of at least one electrode can be within the gas chamber. Alternatively, singularly or in conjunction, one or both electrodes can be attached to the outside of an exemplary syringe. One or more electrical contact points can be outside the gas chamber. Each electrical contact point can be connected to an electrode. Oxygen gas can provided within the gas chamber of the exemplary syringe. A medical ozone generator can be connected to the syringe via the electrical contact points. Corona discharge can be effectuated via the electrodes, which can result in an amount of ozone gas can being produced from the oxygen gas.
US08486341B2	System and method for treating exhaust gases Systems and methods for treating exhaust gases are described. The described systems and/or methods for treating exhaust gases could be used with any power plant, engine, hydrocarbon burning system, other NOx producing system, or combinations thereof. A method (400) for treating exhaust gases is provided. The method (400) may include converting (402) ammonia (44) and NOx to nitrogen and water using an ammonia-SCR catalyst (30) after converting (404) ammonia to NOx using an ammonia-to-NOx catalyst (20) located upstream of at least a portion of the ammonia-SCR catalyst (30). The described systems and/or methods create NOx so excess ammonia added to the exhaust stream may be used to convert NOx to nitrogen and water.
US08486338B2	Gas-liquid contactor A contactor for reacting a flow of gas with a liquid, comprises a vessel, a first chamber in the vessel and a second chamber in the vessel, the first and second chambers being linked only by a porous wall, and means for directing ultrasonic noise into at least one of the first and second chambers.
US08486334B2	Magnetic sensor The invention is to provide a magnetic sensor capable of detecting magnetic particles over a wide range of number and of suppressing an increase in a detection area. The magnetic sensor includes a detection part, a selecting device connected electrically to an end of the detecting part, and a sensing amplifier for receiving a signal from the detecting part, wherein the detecting part includes at least two magnetoresistive films serially connected.
US08486333B2	Centrifugal fluid analyzer rotor This invention provides rotors and methods of precisely metering a sample fluid and mixing the sample with a reagent. The rotors have a metering tube of defined volume that fills until sample flow is stopped by surface tension of a meniscus at a capillarity port, while excess sample is stripped from the metering tube inlet by centripetal force of the spinning rotor. By spinning the rotor at a higher speed, a reagent can be forced from a reagent chamber to contact the meniscus, breaking the surface tension and allowing the metered sample to mix with the reagent.
US08486331B2	Sterilization effects of acidic ozone water This invention is directed to a sterilization method of contaminated areas with biological agents by making use of the acidic ozone water that very effectively kills spores of Bacillus atrophaeus, thereby demonstrating the capability of sterilizing a large surface-area in a very short time and reinstating the contaminated environment as free from toxic biological agents. The effective sterilization of the acidic ozone water is due to synergic benefits derived from the combination of ozone and acidity. The acidic ozone water can also effectively kill other ordinary microbes of viruses, bacteria, and fungi, hence being applicable to agriculture, seafood and livestock industries for the preservation of various products as well as being useful in hospitals or other germ infested areas for disinfections. Particularly, the acidity and ozone in the seawater sterilize microbes effectively, demonstrating a potential for the sterilization of a large amount of seawater in a short time. After the decontamination process, the acidic ozone water disintegrates into water and oxygen without any trace of harmful materials to the environment.
US08486329B2	Process for production of semisolidified slurry of iron-base alloy and process for production of cast iron castings by using a semisolidified slurry A process for the production of a semi-solidified iron alloy slurry having a crystallized solid phase and a residual liquid phase, wherein a material having a hypoeutectic cast iron composition is used, and an additive agent having a boiling point that is lower than at least a crystallization initiation temperature of primary crystals of the material is added to a melt of the material when the melt temperature is within a specific temperature range of not lower than the crystallization initiation temperature of the primary crystals and not greater than a temperature that is 50° C. higher than the crystallization initiation temperature, to thereby simultaneously conduct the stirring of the melt by the boiling of the additive agent and the cooling of the melt to a temperature falling within a semi-solidification temperature range thereof.
US08486326B2	Method and device for induction stirring of molten metal The invention relates to a method and device for the induction stirring of liquid metal in the bath of a reverberatory furnace by using a traveling magnetic field whose frequency ranges from 50 to 60 Hz. The device is in the form of a module and comprises an inductor of a running magnetic field and an unit, wherein the unit has a channel in the form of a chamber and the inductor is located horizontally under the chamber.
US08486324B2	Method and apparatus for producing tiered containers A method and apparatus for molding a plurality of tiered containers from a single parison. Two or more parisons can be arranged next to each other. A molding apparatus of this invention can have one or more mold sections that can be operated in a controlled fashion to form a stacked or tiered arrangement of containers from a single parison or can be arranged to form an array of containers including two or more columns of containers each having two or more tiered containers, all during a single cycle of the molding apparatus. Each container formed by the method and apparatus of this invention can be blow molded and/or vacuum formed and/or filled and/or sealed. Each seal can be a hermetic seal or any other suitable seal formed through a molding step.
US08486323B2	Rotational molded articles, and method of making the same The instant invention provides rotational molded articles, and method of making the same. The rotational molded articles according to the present invention comprise a polyethylene composition comprising: (a) at least 85 percent by weight of the units derived from ethylene; and (b) less than 15 percent by weight of units derived from one or more α-olefin comonomers; wherein the polyethylene composition has a density in the range of 0.930 to 0.945 g/cm3, a molecular weight distribution (Mw/Mn) in the range of 1.70 to 3.50, a melt index (I2) in the range of 0.5 to 20 g/10 minutes, a molecular weight distribution (Mz/Mw) in the range of less than 2.5, vinyl unsaturation of less than 0.06 vinyls per one thousand carbon atoms present in the backbone of the polyethylene composition.
US08486319B2	Articles with super-hydrophobic and/or self-cleaning surfaces and method of making same Super-hydrophobic and self-cleaning articles produced by imprinting exposed surfaces with suitable fine-grained and/or amorphous metallic embossing dies to transfer a dual surface structure, including ultra-fine features less than or equal to 100 nm embedded in and overlaying a surface topography with macro-surface structures greater than or equal to 1 micron are disclosed.
US08486318B2	Fiber, fiber aggregate and adhesive having the same Provided is a functional fiber and a fiber aggregate for realizing various functions, an adhesive for easily bonding electronic components, and a method for manufacturing the same. Particularly, a fiber extended in a length direction includes a carrier polymer and a plurality of functional particles, wherein the plurality of functional particles are embedded in the carrier polymer and physically fixed to the carrier polymer to be integrated.
US08486316B2	Process and plant for the continuous manufacturing of at least a layer of latex foam with recesses Continuous manufacture of at least a layer of latex foam with recesses of unlimited length to be divided in a plurality of blocks of latex foam by transverse cuts. The layer has a thickness between 10 and 20 cm and more. The process includes advancing along a predetermined longitudinal direction a metal laying surface provided with protuberances, gelating, curing. The process includes: a) Before depositing the latex foam inserting, by interference fit, supporting elements of resilient deformability having a predetermined thickness between pairs of protuberances of horizontal rows, the supporting elements of unlimited length; b) Carrying away the supporting elements with the advancing laying surface between an injection latex foam station and a layer extracting station; c) Embedding with latex foam the supporting elements. Advantageously the process forwards the blocks to a washing station and squeezes the blocks to a thickness reduction between 3% and 5% of their initial thickness.
US08486310B2	Composition containing fine silver particles, production method thereof, method for producing fine silver particles, and paste having fine silver particles A composition containing fine silver particles which have a uniform particle size, can form a fine drawing pattern, and have a small environmental impact, a method for producing that composition, a method for producing fine silver particles, and a paste having fine silver particles are provided. The fine silver particles are produced by carrying out a fluid preparation step of preparing a reduction fluid, a silver reaction step, and a filtration/washing step. The reaction step is carried out by adding an aqueous silver nitrate fluid to a reduction fluid whose temperature has been increased to a range between 40 and 800 ° C. The aqueous silver nitrate fluid is added at a stretch. The composition containing fine silver particles is produced by dispersing the composition containing the fine silver particles in a polar fluid.
US08486307B2	Silver micropowder having excellent affinity for polar medium, and silver ink Provided are silver nanoparticles having a good affinity (that is, dispersibility) for y-butyrolactone (C4H6O2), an organic solvent which has a relatively high boiling point though having a relatively small molecular weight, and has a low viscosity and a low surface tension and which has little irritating odor. The above problems are solved by providing a silver micropowder excellent in affinity for at least y-butyrolactone, which comprises silver particles processed to adsorb at least one of 1,4-dihydroxy-2-naphthoic acid (C11H8O4) and gallic acid (C7H6O5) on the surfaces thereof and having an X-ray crystal particle diameter DX of from 1 to 40 nm, preferably from 1 to 15 nm. The invention also provides a silver ink obtained by dispersing silver particles processed to adsorb an organic compound having a carboxyl group on the surfaces thereof and having an X-ray crystal particle diameter DX of from 1 to 40 nm, preferably from 1 to 15 nm (or having a mean particle diameter DTEM, as measured through TEM microscopy, of from 3 to 40 nm, preferably from 4 to 15 nm), in y-butyrolactone.
US08486301B2	Method of preparing and utilizing a catalyst system for an oxidation process on a gaseous hydrocarbon stream The disclosure relates to a method of utilizing a catalyst system for an oxidation process on a gaseous hydrocarbon stream with a mitigation of carbon accumulation. The system is comprised of a catalytically active phase deposited onto an oxygen conducting phase, with or without supplemental support. The catalytically active phase has a specified crystal structure where at least one catalytically active metal is a cation within the crystal structure and coordinated with oxygen atoms within the crystal structure. The catalyst system employs an optimum coverage ratio for a given set of oxidation conditions, based on a specified hydrocarbon conversion and a carbon deposition limit. Specific embodiments of the catalyst system are disclosed.
US08486299B2	Blue phosphors, white light illumination devices and solar cells utilizing the same The invention provides phosphors composed of Eu(1-x-w)MaxMbwMgMc10O17, wherein Ma is Yb, Sn, Ce, Tb, Dy, or combinations thereof, and 0
US08486297B2	Thiophene derivatives, and LC media comprising same The present invention relates to thiophene derivatives, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, and to LC media and LC displays comprising same.
US08486296B2	Battery grade cathode coating formulation A process for preparing a formulation comprising a carbon-deposited lithium metal phosphate, as precursor of a lithium ion battery electrode coating slurry.
US08486295B2	Alkyl perfluoroalkene ethers and uses thereof Disclosed are methods of transferring heat comprising providing a device, using a heat-transfer fluid to transfer heat to or from the device, wherein the heat-transfer fluid compositions comprise at least one unsaturated fluoroether having the formula CF3(CF2)xCF═CFCF(OR)(CF2)yCF3, CF3(CF2)xC(OR)═CFCF2(CF2)yCF3, CF3CF═CFCF(OR)(CF2)x(CF2)yCF3, CF3(CF2)xCF═C(OR)CF2(CF2)yCF3, or mixtures thereof, wherein R can be either CH3, C2H5 or mixtures thereof, and wherein x and y are independently 0, 1, 2 or 3, and wherein x+y=0, 1, 2 or 3.
US08486293B2	Hydrogen fluoride-HFC-254eb azeotrope and its uses Described is a process for separating 1,1,1,2-tetrafluoropropane and hydrogen fluoride from a mixture comprising 1,1,1,2-tetrafluoropropane, 1,1,1,2,3-pentafluoropropane and hydrogen fluoride comprising: subjecting said 1,1,1,2-tetrafluoropropane, 1,1,1,2,3-pentafluoropropane and hydrogen fluoride mixture to a distillation step, forming a column distillate composition comprising an azeotropic or near-azeotropic composition of said 1,1,1,2-tetrafluoropropane and hydrogen fluoride, and a bottoms composition of 1,1,1,2,3-pentafluoropropane. The column distillate may optionally be made essentially free of 1,1,1,2,3-pentafluoropropane and the column bottoms composition may optionally be made essentially free of HF. Also described is a process for separating 1,1,1,2-tetrafluoropropane and hydrogen fluoride from a mixture of 1,1,1,2-tetrafluoropropane and hydrogen fluoride. Also described are azeotropic and azeotrope-like compositions comprising 1,1,1,2-tetrafluoropropane and hydrogen fluoride.
US08486292B2	Magnetorheological formulation Magnetorheological formulations, processes for preparing the same and uses therefor, the formulations comprising: (a) an ionic liquid comprising anions and cations, and (b) dispersed magnetizable particles having a mean diameter of 0.1 to 500 μm; wherein the ionic liquid comprises one or more salts selected from the group consisting of 1-butyl-3-methyl-imidazolium methylsulfate, 1-ethyl-3-methylimidazolium ethylsulfate, 1-ethyl-3-methyl-imidazolium thiocyanate, 1-butyl-3-methylimidazolium thiocyanate, 1-ethyl-3-methyl-imidazolium acetate, 1-butyl-3-methylimidazolium acetate, 1-ethyl-3-methylpyridinium ethylsulfate, 1-ethyl-3-methylimidazolium dicyanamide, 1-butyl-3-methylimidazolium tetrafluoroborate, 1-hexyl-3-methylimidazolium tetrafluoroborate, 1-methyl-3-octylimidazolium tetrafluoroborate, 1-methyl-3-octylimidazolium hexafluorophosphate, 1-ethyl-3-methylimidazolium hexafluorophosphate, 1-hexyl-3-methylimidazolium hexafluorophosphate, methyltrioctylammonium bis(trifluoromethylsulfonyl)imide, 1-ethyl-3-methylimidazolium 2-(2-methoxyethoxy)ethylsulfate and mixtures thereof.
US08486291B2	Plasma processing method In the present invention, provided is a plasma processing method which reduces or eliminates the emission of contaminating matters caused by a quality-altered layer on the surface of yttria of a processing chamber's inner wall and parts inside the processing chamber. It is the plasma processing method including an etching step of setting a sample inside the processing chamber, and etching the sample, a deposition-product removing step of removing a deposition product by using a plasma, the deposition product being deposited inside the processing chamber by the etching step, the plasma being generated using a gas which contains fluorine or chlorine, and a step of exposing, to a rare-gas-based plasma, the inside of the processing chamber after the deposition-product removing step.
US08486284B2	Method for forming a touch sensing pattern and signal wires A method for forming a touch sensing pattern and signal wires, comprises the steps of: installing a first and a second conductive plating films on a surface of a highly transparency substrate; projecting a high energy light beam to the conductive plating films; and the high energy light beam moving with respect to the substrate along a predetermined track; a plurality of insulating trenches being formed in the first and second conductive plating films so as to form predetermined patterns for a sensing area and a wire area; a yellow light process being performed on the substrate; a layer of light resistor thin film being formed on a surfaces of the wire area; and etching the first conductive plating film in the sensing area; by above steps, the predetermined pattern in the sensing area being formed in the second conductive plating film.
US08486281B2	Nickel-chromium alloy stripper for flexible wiring boards A nickel-chromium alloy etching composition comprising sulfuric acid, a source of chloride ions, including hydrochloric acid or sodium, potassium or ammonium chloride, and a sulfur compound comprising a sulfur atom with an oxidation state between −2 to +5, such as thiosulfate, sulfide, sulfite, bisulfite, metabisulfite and phosphorus pentasulfide that can efficiently remove nickel-chromium alloy in the presence of copper circuits is disclosed.
US08486279B2	Silicon-metal composite micromechanical component and method of manufacturing the same The invention relates to a method (1) of manufacturing a silicon-metal composite micromechanical component (51) combining DRIE and LIGA processes. The invention also relates to a micromechanical component (51) including a layer wherein one part (53) is made of silicon and another part (41) of metal so as to form a composite micromechanical component (51). The invention concerns the field of timepiece movements.
US08486277B1	Internal bypass filtration circuit An internal bypass filtration circuit including a microfine depth filtration cartridge, which operates in combination with the sump filter of an automatic transmission is disclosed. The present depth filtration cartridge functions to remove particulate matter as small as five microns to improve fluid cleanliness level without restricting fluid flow to the pump ensuring its volumetric efficiency. In one embodiment transmission fluid passes through a calibrated orifice in the bypass circuit to regulate flow to the depth filtration cartridge. In an alternate embodiment the depth filter media itself regulates filtration below a predetermined fluid pressure. The internal bypass circuit is installed by accessing a pressurized fluid circuit in the transmission valve body. A hydraulic bypass line interconnects such pressurized fluid circuit with the depth filtration cartridge, which is mounted internally of the transmission housing. The outlet of the depth filtration cartridge exhausts directly into the sump bypassing all other functional circuits.
US08486276B2	Method of treating water and aqueous systems in pipes with chlorine dioxide The present invention relates to a method of treating water and an aqueous system, situated in a pipe, with chlorine dioxide (ClO2), the method including generating ClO2 in a reaction space such that the generated ClO2 is completely surrounded by a system to be treated, and delivering the ClO2 generated in the reaction space to the system to be treated which is situated in the pipe, wherein the system surrounding the reaction space is the system to be treated, the reaction space is a component of a mobile device and the mobile device can be introduced into the pipe, in which the system to be treated is situated, and removed again independently of the pressure state of the pipe containing the system to be treated, and the reaction space is situated in the pipe containing the system to be treated.
US08486275B2	Self-contained portable multi-mode water treatment system and methods An automated water treatment system and methods for treating raw water to produce potable water are disclosed. The system is a self-contained portable water treatment system having several selectable treatment subsystems and a controller which automatically selects and controls the mode of operation from a transient, normal or backwashing mode, automatically controls the flow of water through a treatment path based upon the selected mode of operation and the measured water quality characteristics of the water at selected locations, automatically determines, based upon the selected mode of operation and the water quality parameter measurements, which of the plurality of the selectable subsystems is needed to produce potable water at the output; and automatically direct the flow of water through a treatment path through the system to bypass the water treatment subsystems and elements that are not needed to produce potable water. The system is configured to fit inside a standard-sized commercial shipping container for transport and during operation.
US08486274B2	Stimulant sensitive flocculation and consolidation The present invention relates to methods for the separation of materials from heterogeneous fluids and provides a means of effecting stimulant-sensitive flocculation and consolidation of solid suspensions within a liquid medium. Specifically, the present invention provides a method of controlling the state of a suspension of solid particles in a liquid, including applying to the suspension a stimulus adapted to control inter-particle forces between the solid particles. The stimulus is reversibly operable to control attraction and/or repulsion. Means of consolidating a sediment bed and of separating the resultant liquids-rich and solids-rich phases are also within the ambit of the invention.
US08486266B1	Bacterial cultivation system for growth of substrate specific micro-organisms for use in industrial wastewater remediation A waste treatment method includes the concentration of selected strains of bacteria in a selected medium in the presence of nutrients and water, under aerobic conditions. This concentrated batch is discharged for downstream applications in wastewater remediation. A cultivation chamber having inlet ports and a circular vent port allows for adequate air introduction and heat release. Aeration is achieved by recirculation of the fluid medium from the top of the apparatus through a pipe that runs the length of the inner wall and is specially configured at the top to minimize cell damage. Fluid can be routed tangentially in clockwise and counterclockwise directions. The conical bottom has an orifice allowing for recirculation of the fluid medium tangentially to the sidewalls. Upon completion of batch cultivation, the medium and bacteria are discharged for downstream applications in wastewater remediation of paper mill, chemical plant, oil refinery, and other industrial effluents.
US08486264B2	Housing for reverse osmosis filter cartridge and method of forming same Housings for reverse osmosis filter cartridges and methods of making the same. The housings include: (1) a hollow cylindrical liner formed of a thermoplastic polymer that is adapted to surround a reverse osmosis filter cartridge; (2) a hollow head assembly that includes a transition collar portion formed of a thermoplastic polymer that is joined to said liner and a barrel portion formed of a chopped glass fiber-filled polymer that is overmolded onto said transition collar portion; (3) an end plug that is adapted to be received within an opening in the barrel portion; and (4) an overwrap layer comprising wound glass filaments and a polymeric resin that covers the outer surfaces of the liner and head assembly.
US08486263B2	Filter with expandable end cap facilitating easier change-out An improved filter arrangement solves problems associated with dislodging the filter from a support basket at change-out when intimate contact between the filter and basket is no longer desirable. An elastomeric end cap is bonded to the distal end of the filtering medium. The end cap has a circular, outer perimeter defining a diameter less than the inner diameter of the filter basket. The end cap is dome shaped, such that when the filtering element is inserted into the filter basket with the end cap positioned adjacent the bottom of the filter basket, the end cap assumes a pressurized state when a fluid entering the filtering element applies pressure to the end cap, causing the outer perimeter of the end cap to expand radially outwardly, and a non-pressurized state wherein the outer perimeter of the end cap contracts, facilitating an easier removal of the element from the basket.
US08486262B2	Eco-resource slag effective utilization system Slags, including the harmful-substance-containing slags, are not directly melted but are neutralized and processed into eco-resource materials, so that the slugs can be effectively utilized to purify and revive a large area of polluted water without any burden on the environment. Predetermined proportions of a non-recyclable harmful-substance-containing unused slag selected from by-product slags produced during the refining of a metal such as iron, copper, or aluminum from an ore, a porcelain clay for ceramics, and a mineral clay for ceramics, such as a quartz powder or an alumina powder, are kneaded to form a clay material with a suitable size. The clay material is burnt in a burning oven for ceramics at a predetermined temperature for a predetermined period of time so that a liquid glaze can sufficiently penetrate into the inner region of the clay material, thereby forming a biscuit clay material. A liquid glaze produced by kneading a powder made from a crushed special natural stone with a glaze for ceramics in a predetermined ratio followed by aging is applied, for example, to the biscuit clay material. As a result, a harmful-substance-containing unused slag is neutralized and used as an eco-resource filter medium.
US08486261B2	Fuel scavenge water removal system An aircraft fuel scavenge system incorporates a scavenge pump receiving fuel from a center tank and depositing the fuel in a wing tank. A water separator receives fuel through an inlet tube providing a plurality of momentum changes to incoming fuel, the water separator having a fuel outlet connected to the scavenge pump and a water outlet. A water manifold is connected from the water outlet to an input to a fuel supply line to an engine.
US08486254B2	Washing apparatus and method of deodorizing washing water A washing apparatus and a method of deodorizing washing water that can prevent the unpleasant smell of washing water are provided.An electrolytic water producing means 2 produces strong acidic water and strong alkaline water by electrolysis of an electrolytic solution. The produced strong acidic water and strong alkaline water are stored in an acid container 3 and alkali container 4, respectively. A mist container 5 connected to the alkali container 4 produces a deodorant mist upon receiving a part of the strong alkaline water in the alkali container 4. A discharge port 6a is selectively connected to the acid container 3, alkali container 4, or water pipe 8 so as to discharge the strong acidic water, strong alkaline water, or tap water. A mist ejection portion 7 is formed to spray the deodorant mist of the strong alkaline water in the mist container 5 around the strong acidic water or tap water discharged from the discharge port 6a so that the mist surrounds the strong acidic water or tap water.
US08486253B2	Process for electrocoagulation fluid treatment A process for electrocoagulation fluid treatment utilizing a tubular member with a plurality of electrocoagulation assemblies disposed therein. The assemblies have first and second conductive plates that are angularly oriented in relation to one another to promote turbulent flow through the tubular member. A non-conductive block is positioned between the plates to stabilize and orient the plates within the tubular member. The conductive plates may be provided with alternating negative and positive charges to combat corrosion.
US08486251B2	Process for regenerating alkali metal hydroxides by electrochemical means This invention relates to the desulfurization of a hydrocarbon feedstock by contacting said feedstock with an aqueous metal hydroxide solution, thus resulting in a desulfurized feedstock and an aqueous metal sulfide stream. In the present invention, the aqueous metal sulfide stream is split into at least three fractions and each fraction is passed to a different electrochemical cell, connected in series to regenerate the metal hydroxide required in the desulfurization process and recover sulfur, metal hydroxide, and hydrogen. In a preferred embodiment, at least a portion of the metal hydroxide that is produced in the electrochemical metal hydroxide regeneration process of the present invention is recycled for use in the process for desulfurizing the sulfur-containing hydrocarbon feedstock.
US08486250B2	Electrodeposition method of forming a probe structure having a plurality of discrete insulated probe tips projecting from a support surface The present invention is directed to structures having a plurality of discrete insulated elongated electrical conductors projecting from a support surface which are useful as probes for testing of electrical interconnections to electronic devices, such as integrated circuit devices and other electronic components and particularly for testing of integrated circuit devices with rigid interconnection pads and multi-chip module packages with high density interconnection pads and the apparatus for use thereof and to methods of fabrication thereof. Coaxial probe structures are fabricated by the methods described providing a high density coaxial probe.
US08486245B2	Methods for measuring physiological fluids Electrochemical measurement techniques for measuring the concentration of an analyte in a physiological fluid sample are described. More particularly, the present invention relates to techniques for distinguishing a signal caused by an extraneous event from a desired information providing signal such as one indicative of a measurement error.
US08486244B2	Test strip comprising patterned electrodes Described herein is an electrochemical enzymatic analyte test strip and method for making the test strip. The test strip utilizes isolated conductive areas inside the electrodes to define electrode whiskers. The method utilizes laser ablation to define electrode patterns.
US08486243B2	Electrochemical cell The present invention relates to electrochemical cells including a first working electrode 32, a first counter electrode 34, a second working electrode 36, and a second counter electrode 38, wherein the electrodes are spaced such that reaction products from the first counter electrode 34 arrive at the first working electrode 32, and reaction products from the first and second counter electrodes 34, 38 do not reach the second working electrode 36. Also provided is a method of using such electrochemical cells for determining the concentration of a reduced or oxidized form of a redox species with greater accuracy than can be obtained using an electrochemical cell having a single working and counter electrode.
US08486242B2	Deposition apparatus and methods to reduce deposition asymmetry One or more embodiments of the invention are directed to deposition apparatuses comprising a grounded top wall, a processing chamber and a plasma source assembly having a conductive hollow cylinder and a magnet outside the conductive hollow cylinder capable of affecting the current density on the conductive hollow cylinder.
US08486235B2	Alkaline zinc-nickel bath The anode is separated from the alkaline electrode to avoid undesirable secondary reactions in an alkali zinc nickel electroplating bath.
US08486232B2	Cleaning device for the frame of a coke oven retort A cleaning device for the frame of a coke oven retort has a tool carrier positioned between anchor stands of the coke oven retort and exhibits cleaning apparatuses for the frame of the coke oven retort, sheet-shaped sealing elements being arranged on the tool carrier. The sealing elements are secured to the reverse side of the tool carrier, which side faces away from the coke oven retort. The sealing elements are orientated vertically and completely cover the height of the reverse side. The sealing elements consist of at least one central piece which is immovably fixed to the tool carrier and of side wings, the side wings being connected with the central piece in such a manner as to be rotationally moveable on vertical axes. The side wings are moveable in an adjusting movement in the direction of the coke oven retort against the front surfaces of the anchor stands.
US08486229B2	Device for drying and treating a tissue paper web A device for drying and treating a fiber-based moving fiber web (1) in a machine intended for producing tissue paper includes a metal belt (2) which is arranged to support the fiber web (1) and to transfer the fiber web (1) in the machine direction and which metal belt (2) is arranged as a continuous rotating cycle, at least one roll (3) the shell of which is in contact with the metal belt (2) arranged to rotate around, which roll (3) is for supporting and/or controlling the metal belt (2), and at least one counter element (5) arranged to create a contact area outside the metal belt (2) between the metal belt (2) and the counter element (5) for a process zone (6), via which process zone (6) the fiber web (1) is arranged to travel when using the device.
US08486225B2	Bleached fiber product production method, apparatus to be used therefor, and bleached fiber product produced thereby An inventive method includes the steps of: loading a fiber product in an appropriate form into a treatment vessel; wetting the fiber product; forcibly circulating an ozone-containing liquid in contact with the wetted fiber product to thereby bleach the fiber product; and forcibly circulating an ozone decomposing chemical agent liquid in contact with the ozone-treated fiber product to decompose ozone. This method ensures efficient bleaching of the fiber product with the ozone. Further, the method is advantageous in that the resulting bleached fiber product is less liable to be yellowed over time.
US08486219B2	Paper laminates having improved easy clean and abrasion resistance properties The present disclosure pertains to a process for preparing a laminate comprising: providing a dried overlay and a base sheet wherein at least one of the dried overlay and the base sheet comprises a resin-impregnated, opaque, cellulose pulp-based sheet; applying a fluorourethane to the dried overlay to form a treated overlay; drying the treated overlay; and laminating the treated overlay to the base sheet. The disclosed process hereby produces a laminate whose outer surface is modified with the fluorourethane and the cleanability, oil repellency, and abrasion resistance of such a laminate is improved.
US08486216B2	Process for forming fiber-containing articles such as annular or ellipsoidal preforms A process for placing at least one fiber element on a surface is disclosed so as to provide a deposited fiber element having a width that varies longitudinally. The process may provide a step in which the width of the fiber element is modified upstream of the deposition step using a width control device. A device for performing the process is also disclosed. Further, fibrous sheets containing one or more deposited fiber element having a width that varies longitudinally are also disclosed. Preforms formed from one or more of the fibrous sheets are also disclosed.
US08486214B2	Ramped, variable power UV adhesive cure process for improved alignment Methods and apparatuses for adhering optoelectronic components in optical, electronic or optoelectronic devices are disclosed. A UV-active adhesive is applied to an alignment sensitive component of the device. A first, relatively low dose of UV radiation sufficient to solidify an outer layer of the adhesive is applied to the adhesive. A second, relatively high dose of UV radiation sufficient to solidify the remaining thickness of the adhesive is then applied. The methods and apparatuses of the present invention advantageously reduce or eliminate changes in the position of a component during the adhesive curing process. The present method and apparatus allow for shorter total time for solidifying the adhesive, provide stable positioning during the adhesive solidification process, and enable increased manufacturing output and decreased waste.
US08486204B2	Hinge device and electronic device using the same The hinge is made with a metal injection molding process from an alloy having at least: from 4 to 32 wt % Mn, from 16 to 37 wt % Cr, and from Fe that fills up the rest of the percentage.
US08486192B2	Thermalizing gas injectors for generating increased precursor gas, material deposition systems including such injectors, and related methods Methods of depositing material on a substrate include forming a precursor gas and a byproduct from a source gas within a thermalizing gas injector. The byproduct may be reacted with a liquid reagent to form additional precursor gas, which may be injected from the thermalizing gas injector into a reaction chamber. Thermalizing gas injectors for injecting gas into a reaction chamber of a deposition system may include an inlet, a thermalizing conduit, a liquid container configured to hold a liquid reagent therein, and an outlet. A pathway may extend from the inlet, through the thermalizing conduit to an interior space within the liquid container, and from the interior space within the liquid container to the outlet. The thermalizing conduit may have a length that is greater than a shortest distance between the inlet and the liquid container. Deposition systems may include one or more such thermalizing gas injectors.
US08486191B2	Substrate reactor with adjustable injectors for mixing gases within reaction chamber Methods and apparatuses for separately injecting gases into a reactor for a substrate processing system. The flow profiles of the gases are controlled with two or more sets of adjustable gas flow injectors. The methods are particularly useful for selective deposition of gases in a CVD system using volatile combinations of precursors and etchants. In either case, the gases are provided along separate flow paths that intersect in a relatively open reaction space, rather than in more confined upstream locations.
US08486185B2	Inkjet recording ink, ink cartridge and inkjet recording apparatus An inkjet recording ink containing: water; a water-soluble organic solvent; a colorant; and at least one fluorochemical surfactant having a formula selected from the group consisting of (b), (a), (a′), and (h): [(RfSO2)2]N−M+ (a), [(RfSO2)(RSO2)]N−M+ (a′), [(FSO2)2]N−M+ (h), wherein M+ is Li+, Na+, K+, or NH4+, Rf is CF3, C2F5, C3F7, or C4F9, and R is C1-C10 alkyl group.
US08486183B2	Alkylamino alkyloxy (alcohol) monoalkyl ether for acid gas scrubbing process An acid gas absorbent comprising an alkylamino alkyloxy (alcohol) monoalkyl ether and a process for the selective removal Of H2S from gaseous mixtures containing H2S and CO2 using an absorbent solution comprising an alkylamino alkyloxy alcohol monoalkyl ether.
US08486182B2	Method and system for removing carbon dioxide from exhaust gas by utilizing seawater According to one embodiment, a method for removing carbon dioxide in an exhaust gas utilizing seawater includes: blowing ammonia into seawater to produce ammonia-saturated seawater; contacting an exhaust gas under a state of non-heat with the ammonia-saturated seawater so that carbon dioxide in the exhaust gas is absorbed in the ammonia-saturated seawater; and splaying a solution containing sodium hydrogen carbonate and ammonium chloride which are produced through absorption of the carbon dioxide by the ammonia-saturated seawater utilizing pressure of the exhaust gas while cooling the solution utilizing heat of evaporation of a solvent of the solution so as to settle out and recover the sodium hydrogen carbonate and the ammonium chloride.
US08486181B2	Slow releasing device for gaseous chlorine dioxide and method for making same A method for making a slow releasing device for slowing releasing chlorine dioxide includes sending gaseous chlorine dioxide into a receiving container containing a plurality of particulate carriers. Each particulate carrier has a plurality of pores in a surface thereof. The receiving container is placed in a low-temperature environment below 30° C. The gaseous chlorine dioxide is absorbed by the particulate carriers. The particulate carries is packaged in at least one container that is subsequently sealed. The gaseous chloride dioxide can be purified before entering the receiving container. Superfluous chloride dioxide can be dissolved or absorbed in water in an absorbing tank on a circulating pipeline connected to the receiving container via an outlet pipe.
US08486176B2	Method for filtering molten aluminum and molten aluminum alloys A method for filtering molten aluminum and aluminum alloys. The method includes providing a reticulated foam wherein oxygen is introduced to an interior of the reticulated foam. Molten aluminum or aluminum alloy is passed through the reticulated foam wherein oxygen is maintained at a partial pressure of at least 2.51×10−35 atm during filtration.
US08486174B2	Filter arrangement; sealing system; and methods A filter pack includes a filter construction and a sealing system for sealing the construction within a duct or housing. The filter construction has first and second opposite flow faces and is configured for a straight-through flow. The sealing system includes a frame construction and a compressible seal member. The compressible seal member is molded around a portion of the frame construction. The compressible seal member is sufficiently compressible to form a radial seal between and against the frame construction and a surface of a housing when the filter pack is inserted within the housing.
US08486172B2	Filter element arrangement and end cap interface feature A filter element including an end cap is provided. The end cap includes an annular seal support carrying an annular seal member and a mounting arrangement to seal and support the filter element in a filter housing. The end cap is configure to engage with a mating engagement structure of the housing to provide self alignment feature of the filter element.
US08486171B2	Dry dust removal method in organic chlorosilane production Dry dust removal method in organic chlorosilane production is provided, in which the detailed steps are as follows: delivering high-temperature flue gas (a) from fluidized bed reactor (I) into inorganic film cross-flow filter (E) to remove dust for the first time; delivering the concentrated dust gas (c) trapped by inorganic film cross-flow filter (II) into bag filter (III) to remove dust for the second time; returning the gas mixture (f) of passing through bag filter (EI) to the air intake of inorganic film cross-flow filter (II); condensing the residual clean gas (b) from the osmotic side of inorganic film in condenser (A), and then rectifying in rectifying column (B) to separate the products of chloromethane (g) and methyl chlorosilane (h) to obtain the product of methyl chlorosilane (h); returning chloromethane to fluidized bed reactor to take part in reaction; retreating the dust (e) trapped by inorganic film cross-flow filter and bag filter, and then returning it to fluidized bed reactor (I) to take part in reaction.
US08486166B2	Fuel reforming apparatus Fuel reforming catalysts 28 generate a hydrogen-containing reformed gas when they come into contact with exhaust gas that contains a reforming fuel. Upstream and downstream air-fuel ratio sensors 58, 60 are respectively installed upstream and downstream of the fuel reforming catalysts 28. The upstream air-fuel ratio sensor 58 outputs a upstream sensor signal in accordance with oxygen concentration. The downstream air-fuel ratio sensor 60 outputs a downstream sensor signal in accordance with oxygen concentration and hydrogen concentration by using zirconia's oxygen detection capability and a change of a diffusion layer's hydrogen-concentration-dependent oxygen detection capability. An ECU 50 detects the hydrogen concentration without being affected by the oxygen concentration through the use of the upstream sensor signal in which only the oxygen concentration is reflected and the downstream sensor signal in which the oxygen concentration and hydrogen concentration are reflected. This makes it possible to establish a hydrogen concentration detection system with the common air-fuel ratio sensors 58, 60.
US08486165B2	Heat recovery in black water flash systems In one embodiment, a gasification system includes a black water processing system with flash tanks. The flash tanks may separate gases from black water to produce a first discharge of the black water and another discharge of separated gases. The gasification system also includes a heat exchanger that transfers heat from the discharge of separated gases to a process stream of the gasification system.
US08486161B2	Lignin upgrading for hydroprocessing to biofuel The present invention is generally directed to methods for processing lignin-containing biomass so as to render it more amenable to hydroprocessing, wherein such processing typically reduces the level of oxygen in the biomass. Following such processing, the resulting reduced-oxygen lignin-derived product can be hydroprocessed into a biofuel suitable for use as a transportation fuel. Additionally, in some embodiments, such methods can be integrated with one or more other processes, wherein such other processes can be production and/or logistical in nature.
US08486154B2	Resorbable intra-urethral prosthesis The device made in a resorbable material intended to be placed in urethra for Treatment of stricture has the shape of a tube (1), the wall of which has offices (2).
US08486152B2	Coated implant An orthopedic implant comprising a metallic substrate coated with a diamond-like carbon (DLC) layer, and a layer of a polymeric material placed over the DLC layer that is less stiff than the substrate, and methods of manufacturing the same.
US08486149B2	Expandable interbody fusion implant Disclosed is an expandable interbody fusion implant that is configured to have an initial configuration having a first footprint width suitable for being inserted into an intervertebral space and an expanded configuration having a second footprint width that is greater than the first footprint width. The implant may include a first body member and a second body member that is pivotally coupled to the first body member. The implant may be expanded using an inflatable balloon. The implant may be expanded bilaterally such that both body members rotate relative to the other or the implant may be expanded unilaterally such that one of the body members rotates relative to the other.
US08486144B2	Endoprosthesis having a plug-in connection and improved rotary protection The invention relates to an endoprosthesis, particularly for the at least partial replacement of a long bone, comprising a plug-in connection for connecting a shaft (2) to another part (1) of the prosthesis, wherein the plug-in connection (3) comprises an axial projection (33) and a socket (34). According to the invention, provision is made that a radial transverse channel (53) is provided on one part of the plug-in connection (3), said radial transverse channel (53) engaging behind the plug-in connection and having a center axis (55) that is offset (d) relative to the axis (56) of a transverse bore (52) arranged on the other part of the plug-in connection, and a clamping element (6) which is to be inserted into the transverse channel (53) and whose point (62), in the inserted state, engages in the transverse bore (52). In this way, it is possible to achieve an effective securing action even in the event of an unfavorable tolerance pairing, without adversely affecting the sensitive projection itself.
US08486143B2	Mechanically competent scaffold for ligament and tendon regeneration A multi-region device for repair, regeneration or reconstruction in articular tissue injury such as torn ligaments and tendons is provided. The device comprises at least one degradable material and biocompatible non-degradable polymeric fiber-based material, in a three-dimensional braided scaffold. The two end sections are designed for attachment of the device at the site of implantation and are designed to allow bone cell ingrowth, and one or more middle regions are designed to allow ligament or tendon cell ingrowth.
US08486141B2	Multi-zonal monofocal intraocular lens for correcting optical aberrations A multi-zonal monofocal opthalmic lens comprises an inner zone, an intermediate zone, and an outer zone. The inner zone has a first optical power. The intermediate zone surrounds the inner zone and has a second optical power that is different from the first power by a magnitude that is less than at least about 0.75 Diopter. The outer zone surrounds the intermediate zone and has a third optical power different from the second optical power. In certain embodiments, the third optical power is equal to the first optical power.
US08486139B2	Method of preparing decellularized soft tissue, graft and culture material It is intended to provide a method of preparing a decellularized soft tissue whereby swelling after an ultrahigh pressure treatment can be inhibited, etc. The above-described method of preparing a decellularized soft tissue comprises the application step wherein an ultrahigh hydrostatic pressure is applied to an isolated soft tissue in a medium to thereby disrupt cells in the soft tissue, and the removal step wherein the disrupted cells are removed. As the medium, use is made of an aqueous solution containing a water-soluble polysaccharide such as dextran.
US08486131B2	Extra-vascular wrapping for treating aneurysmatic aorta in conjunction with endovascular stent-graft and methods thereof A system for treating an aneurysmatic abdominal aorta, comprising (a) an extra-vascular wrapping (EVW) comprising (i) at least one medical textile member adapted to at least partially encircle a segment of aorta in proximity to the renal arteries, and (ii) a structural member, wherein EVW is adapted for laparoscopic delivery, and (b) an endovascular stent-graft (ESG) comprising (i) a compressible structural member, and (ii) a substantially fluid impervious fluid flow guide (FFG) attached thereto. Also described is an extra-vascular ring (EVR) adapted to encircle the neck of an aortic aneurysm. Further described are methods for treating an abdominal aortic aneurysm, comprising laparoscopically delivering the extra-vascular wrapping (EVW) and endovascularly placing an endovascular stent-graft (ESG). Also described are methods to treat a type I endoleak.
US08486121B2	Bone anchoring device A bone anchoring device includes a shaft for anchoring in a bone and a head, the shaft including a first section having a plurality of barb elements, the barb elements being elastically deformable relative to the body of the shaft, and a second section including a bone thread for engagement with the bone. The first section is located near the tip of the shaft and allows insertion by pushing whereas the second section provides enhanced resistance against pull-out.
US08486120B2	Implant with deployable stabilizers An implant includes a body having an upper and lower ends, a longitudinal bore defined by a threaded interior surface, and a threaded exterior surface; at least one stabilizer arm associated with a corresponding longitudinal slot in the body, the stabilizer arm being hingedly attached to the body and having a bone gripping protuberance projecting laterally outward therefrom. The stabilizer arm is movable from a first position wherein the bone gripping protuberance is positioned within the bore and a second fully extended position wherein the bone gripping protuberance is positioned outside the threaded exterior surface of the body. The stabilizer arm is resiliently biased to the first position. A camming member is movable through the bore of the body from an initial position to a final position wherein the stabilizer arm is moved to the second stabilizer arm position.
US08486114B2	Cerclage system for bone Cerclage system, including methods, devices, and kits, for stabilizing bone, such as a sternum. The cerclage system may include a wire or cable that encircles bone, and a bone plate to which segments of the wire or cable lock. The cerclage system also or alternatively may include a tensioner for applying tension to a wire or cable.
US08486111B2	Dynamic fixation device and method of use A dynamic fixation device is provided that allows the vertebrae to which it is attached to move in flexion within the normal physiological limits of motion, while also providing structural support that limits the amount of translation motion beyond normal physiological limits. The present invention includes a flexible portion and two ends that are adapted for connection to pedicle screws. In at least one embodiment of the present invention, the normal axis of rotation of the vertebrae is substantially duplicated by the dynamic fixation device. The flexible portion of the dynamic fixation device can include a flexible anterior-posterior segment, an anterior-posterior segment bounded by one or more zones with cuts in the rod portions, a flexible accordion-like segment, and/or a hinge portion.
US08486110B2	Spinal implant and method for restricting spinal flexion A spinal implant system for restricting flexion of a spine includes an elongate band proportioned to engage at least two spinous processes. During use, the band is positioned engaging the spinous processes at a spinal segment of interest, where it restricts flexion at the segment. The length and tension of the band may be adjustable following to implantation using percutaneous or transcutaneous means.
US08486106B2	Disposable digital tourniquets and related methods of providing occlusion pressures to a single digit during surgical procedures A single-use disposable digital tourniquet includes a generally rigid support body comprising first and second spaced apart cuff channels sized and configured to receive a cuff therethrough.
US08486103B2	Balloon dilation catheter having transition from coaxial lumens to non-coaxial multiple lumens A shaft for a balloon dilation catheter comprises a proximal portion wherein a guidewire tubular member is disposed coaxially within an outer tubular member, a shaft transitional portion, wherein the guidewire member is disposed within the outer member, with at least one distal tubular member not present in the proximal portion, a shaft distal portion, wherein the guidewire member and the distal members are disposed side-by-side and encased within a distal body, and fluid-tight barrier within a proximal lumen blocking the flow of fluid in the proximal lumen, but allowing the proximal lumen to remain in fluid communication with a distal lumens.
US08486102B2	Valvuloplasty catheter The present invention provides an aortic valvuloplasty catheter which, in one preferred embodiment, has a tapered distal balloon segment that anchors within the left ventricle outflow track of the patient's heart and a rounded proximal segment which conforms to the aortic sinuses forcing the valve leaflets open. In addition, this embodiment of the valvuloplasty catheter includes a fiber-based balloon membrane, a distal pigtail end hole catheter tip, and a catheter sheath.
US08486100B2	Guide tube having balloons for puncture To provide a guide tube equipped with a balloon for puncture, devised to ensure a deeper level of puncture when the balloon is punctured with a puncture needle, in order to safely and reliably ensure a route for percutaneous approach to the inside of the body.
US08486098B2	Aortic punch An aortic punch including a handle mechanism and punch cartridge for interchangeability of a variety of cartridges with a common handle.
US08486097B2	Tissue cutting device A tissue cutting device includes an outer cannula, and axially fixed inner member, an actuation assembly, a slidable shuttle member, and a vacuum fitting configured to connect to a vacuum source. The outer cannula is configured for selective rotation. The shuttle member is operatively connected to the outer cannula to reciprocate the outer cannula. The axially fixed inner member is disposed within the outer cannula.
US08486095B2	Method and apparatus for radical prostatectomy anastomosis Apparatus for performing a surgical anastomosis include a tubular body having an expandable anchor operatively coupled near a distal end thereof. The apparatus further includes a sleeve slidably received about the tubular body. The sleeve has an expandable anchor operatively coupled near a distal end thereof. The expandable anchor of the tubular body has an annular ring concentric with a longitudinal axis defined by the tubular body.
US08486089B2	Introducer for lead delivery Devices and methods for implanting leads along a spinal cord include an introducer having a main body defining a lumen and one or more collapsible and expandable side sheaths attached to the main body. The side sheaths may be collapsed as the introducer is positioned in a desired location of a patient to maintain a low profile. Once the introducer is placed, the side sheaths may be expanded to receive a lead. A lead may also be inserted through a lumen of the main body. Once the leads are inserted, the introducer may be withdrawn over the leads, leaving the leads implanted in the desired region in a desired orientation.
US08486088B2	Ear tag installation tool and method An apparatus and method of installing livestock ear tags are provided. The apparatus includes handle members that control the insertion of a piercing needle that cuts an opening through an animal's ear. A slidable head assembly enables efficient manipulation of the piercing needle and reload of a new piercing needle for installing another tag. The piercing needle has attached to it a securing tab of the ear tag. The tab is stripped from the piercing needle after the needle clears the far side of the ear thereby securing the tag to the ear by placing the tab on the opposite side of the ear. The piercing needle is preferably disposable. The piercing needle has an integral tissue capturing cavity for capturing a slug of tissue from the animal's ear as the needle passes through the ear. The tissue sample can be used for subsequent animal health testing. The piercing needle is automatically captured by the tool after installation to prevent contamination of the tissue sample by release of the needle onto the ground. Another embodiment uses a tag with an integral needle, and the tag is installed in the same manner by the tool.
US08486086B2	Flow regulating implant, method of manufacture, and delivery device An implant includes a tube for permitting fluid flow. A flow controlling rod may be inserted within the tube passage. One or more holes around the circumference of the tube may be selectively permanently or temporarily occluded to give desired flow characteristics. A delivery device for implanting the implant may include a central bore in which a retractable wire is located. The retractable wire penetrates a tube passage of the implant. After the implant is in position in the eye, the retention wire is retracted out of the implant. In a method for manufacturing an implant, two tubes of different diameters are utilized. The smaller tube fits inside the longitudinal bore of the larger tube. When the tubes are cut, the smaller tube forms the tube of the implant and the remaining portions of the larger tube form the retention projection and/or disk of the implant.
US08486080B2	Bone replacement material delivery devices and methods of monitoring bone replacement material Bone material delivery devices and methods of using the devices are provided. The bone material delivery devices and methods comprise thermochromic material disposed on the exterior of the syringe, the thermochromic material configured to provide an indication of temperature, viscosity, and/or age of bone replacement material in the interior of the syringe. In some embodiments, a time indicating label is disposed on the exterior of the syringe, the time indicating label comprising a label substrate having a first surface comprising an acid-base indicator and a second surface comprising an activator, wherein when the first surface is brought into contact with the second surface or when the second surface is brought into contact with the first surface, at least a portion of the label changes color indicating elapsed time. In some embodiments, the devices and methods allow the practitioner to know the dough time, working time, and setting time of the bone replacement material when it is in the syringe.
US08486076B2	Oscillating rasp for use in an orthopaedic surgical procedure Oscillating rasps for the surgical preparation of the bone prior to the implantation of a glenoid or acetabular component with complex geometry are disclosed. Surgical methods for the use of such oscillating rasps are also disclosed. The oscillating rasp includes an attachment head configured to be secured in a chuck of an oscillating tool, and a cutting head secured to the attachment head. The cutting head includes a cutting surface extending posteriorly from the longitudinal axis of the oscillating surgical rasp. The cutting surface has a plurality of cutting teeth arranged in a geometry that, when oscillated along a predetermined path in contact with the glenoid of the patient, corresponds with the geometry of the augmented glenoid prosthesis.
US08486075B2	Method for using retractable stylet and cannula combination to form an opening in bone In one preferred aspect, a method is provided for forming an opening in bone for the sequential dilation of tissue.
US08486073B2	Coating on a medical substrate and a coated medical product The invention relates in general level to a method for coating articulating surfaces of medical products. The invention also relates to coated medical products manufactured by the method. The coating is carried out by employing ultra short pulsed laser deposition wherein pulsed laser beam is preferably scanned with a rotating optical scanner including at least one mirror for reflecting the laser beam. The invention has several both industrially and qualitatively advantageous effects such as high coating production rate, excellent coating properties and overall low manufacturing costs.
US08486072B2	Implant for treating a proximal fracture of the humerus An intramedullary pin for treating a proximal fracture of the humerus, the pin having at least one distal and at least one proximal part which can be moved in relation to one another in order to modify the length of the implant and which have co-operating guide surfaces. The proximal and the distal part have co-operating stops for limiting the axial relative movement, the proximal part and distal part being capable of relatively free movement within the delimitations defined by the stops and each being provided with at least one transverse bore for receiving and/or fastening fixing means. The implant is also provided with a mechanism for locking the relative movement of the two parts about the implant axis.
US08486067B2	Bone graft applicator A bone graft applicator for applying bone graft to an orthopaedic implant. The bone graft applicator includes a pair of arms and a bone graft receptacle sized and shaped to be able to receive a portion of the orthopaedic implant within the receptacle. The bone graft receptacle is coupled to each of the pair of arms. The bone graft applicator also includes a linking mechanism. The linking mechanism includes a recess sized and shaped to extend at least partially around the portion of the orthopaedic implant and is coupled to the bone graft receptacle.
US08486063B2	Ablation catheter Devices, systems and methods are disclosed for the ablation of tissue. Embodiments include an ablation catheter which has an array of ablation elements attached to a deployable carrier assembly. The carrier assembly can be constrained within the lumen of a catheter, and deployed to take on an expanded condition.
US08486060B2	Power ramping during RF ablation A method for tissue ablation is described. An RF applicator including an electrode carrier with one or more bipolar electrodes thereon is positioned at a target tissue site for tissue ablation. A current at an initial current level is passed through the one or more bipolar electrodes to the target tissue site to apply an initial power density to destroy tissue for an initial time period. A vacuum source in fluid communication with the RF applicator is employed to remove moisture generated during ablation away from the target tissue site. After the initial time period, the power density is ramped up by increasing the current passed through the one or more bipolar electrodes to the target tissue site for a second time period.
US08486059B2	Multi-layer return electrode An electrosurgical return pad including a material backing configured to support first and second conductive materials and an insulative layer disposed therebetween. A switch element is mounted on the first conductive material and is activatable upon reaching a threshold condition, such as temperature. Upon reaching the threshold condition, the switch element automatically activates to provide electrical continuity between the first and second conductive materials to offset the threshold condition.
US08486058B1	Minigenerator The present invention provides an Electro Surgical Generator (ESG) optimized for lung biopsy. The ESG is exclusively battery operated and fits within the handpiece of modern endoscopic electrosurgical/electrocautery instruments, thereby avoiding wires, adapters, and coupling mechanisms. The ESG is adaptable to generate different waveforms that vary with respect to frequency, pulse width, amplitude, etc. through the use of timing circuits and voltage control (i.e. transformers). The ESG is both energy-efficient and safe. A closed loop feedback system featuring a monitor and controller ensure no more power than necessary is provided to achieve a goal current level. Dynamic Power Control (DPC) and Dynamic Temperature Control (DTC) systems vary power to maintain temperature with the lowest possible power. These features prolong battery life and guard against tissue damage. The generator includes other safety features such as resiliency against and the ability to overcome single fault events such as short circuits.
US08486056B2	Treatment of skin disorders with UV light Skin disorders such as, for example, atopic dermatitis, dyshidrosis, eczema, lichen planus, psoriasis, and vitiligo, are treated by applying high doses of ultraviolet light to diseased regions of a patients skin. The dosage employed exceeds 1 MED, an MED being determined for the particular patient being treated, and may range from about 1 MED to about 20 MED or higher. The ultraviolet light has a wavelength within the range of between about 295 nanometers to about 320 nanometers and preferably is between about 300 nanometers and about 310 nanometers. High doses of ultraviolet light are restricted to diseased tissue areas so as to avoid risk of detrimental side affects in healthy skin, which is more susceptible to damage from UV light. Cooling the skin prior to and/or while exposing the skin to the UV light can be used to minimize tissue damage resulting from exposure to the UV light. Higher doses of UV light can therefore be employed without injurious affects.
US08486052B2	Reservoir device for intraocular drug delivery A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.
US08486051B2	Drainage apparatus and method An apparatus for removing body fluids from a body cavity by suction, such as a thorax, gastric or any other human body cavity or a wound, comprises means (9) to increase the pressure difference between a pressure in a drainage lumen (3) and a pressure in the atmosphere when an auxiliary lumen (5) is open. The apparatus enables removal of clots or other plugs of the catheter and drainage tube in an efficient and not patient disturbing way.
US08486050B2	Bubble-type nose cleaner A bubble-type nose cleaner includes a container, an electromagnetic pump, a nose-washing tool, and at least a bubble generating valve. The container has a containing space for storing a cleaning solution. The electromagnetic pump is communicated with the container through a negative pressure channel. The nose-washing tool is communicated with the electromagnetic pump through a positive pressure channel, thereby the nose-washing tool is applied with the cleaning solution drawn by the negative pressure and then discharges the cleaning solution when the electromagnetic pump actuates. The bubble generating valve is provide at a negative pressure channel or a positive pressure channel and has an air inletting opening provided at the negative pressure channel or the positive pressure channel for communicating the exterior with the interior, wherein a cap is used to control the gas-flow rate of the bubble generating valve.
US08486046B2	Occlusion catheter having compliant balloon for use with complex vasculature A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.
US08486031B2	Eye treatment apparatus An eye treatment apparatus having a guide device structured to guide a nozzle of an applicator to a position in front of an eye is provided. The guide device includes a guide surface and a stop. The guide surface is easily accessible. That is, the nozzle of an applicator may be moved, generally laterally, into contact with the guide surface. The nozzle may then slide over the guide surface to the stop. The stop is positioned so that the nozzle is disposed centrally in front of the eye.
US08486025B2	Systems and methods for treating a vessel using focused force A device for introduction into a body vessel includes a main elongated element, a balloon positioned at the main elongated element distal end, a distal connecting element positioned at the distal end of the balloon to receive a guidewire during use, and a longitudinally movable sheath positioned external to the main elongated element, a position of the sheath distal end with respect to the balloon defining an exposed portion of the balloon that expands when fluid is delivered to the balloon through the inflation lumen.
US08486024B2	Safety IV catheter assemblies A safety IV catheter assembly is disclosed which includes a catheter assembly, a needle assembly and a needle guard assembly. The needle guard assembly includes a needle guard, a biasing member and a bushing. The bushing is slidably positioned about the needle and includes an inner diameter which is smaller than an enlarged diameter portion of the needle such that the needle cannot be withdrawn through the bore of the bushing.
US08486023B2	Intrathecal catheter having a stylet with a curved tip An apparatus includes a catheter for an intrathecal drug delivery system and a stylet having a curved forward end. Preferably, the curved forward end has a shape in the form of a “J” or a “C.” Also preferably, the catheter has a distal end that conforms to the curved forward end of the stylet. Thus, the present invention provides a catheter having a blunt forward end that minimizes the risk of penetrating the substance of the spinal cord. Additionally, the curved forward end of the stylet can be formed of a springy material so that it straightens out during the processes of insertion through a guide needle and retraction from the needle.
US08486007B2	Injection device A pen injection device designed for use with dual or multi-chamber cartridges 14, is provided with an extended length plunger 24 having a non-drive portion 24′ on its forward end and the usual screw-threaded drive portion 24″ on its rearward end. This arrangement allows the plunger to be pushed forwardly while the dosing drive mechanism is disengaged to effect a reconstitution movement of the rearward bung 18′ in the cartridge. Thereafter the threaded portion on the plunger 24′ engages the drive mechanism to allow metered dosing.
US08486001B2	Method of treating capsular contracture A method of treating and ameliorating capsular contracture having the steps of providing ultrasound at or near the site of a breast implant, providing specific massage and/or physical manipulation the implant site, and providing a compression bandage at the implant site.
US08485996B2	Method and system for motion improvement A method and system are presented for improving the object's motion. Data indicative of a measured motion of the object is processed, and a relation between the measured motion and a predetermined correct motion is determined. This relation is indicative of an error in the measured motion. Based on the determined error, an operating signal may be generated to be used to apply an effecting force to the object. The operating signal is such that the effecting force, when applied to the object, will increase a value of the error in the object's motion.
US08485994B1	Physical therapy system A physical therapy system featuring a leg portion and at least one arm portion, wherein the leg portion comprises a base with two half cylinders, each divided into two portions that can pivot via hinges operatively connected to motors, wherein the two half cylinders can also pivot about their first ends via a first central motor, and wherein the arm portion comprises a base with a half cylinder divided into two portions that can pivot via a hinge operatively connected to a motor, wherein the half cylinder can also pivot about its first end via a second central motor.
US08485992B2	Medical device having segmented construction A medical device having a segmented construction. In at least some embodiments, a medical device including a plurality of conductive elongated members that are of such a length and are connected together in such a manner to impart a degree of MRI compatibility to the device. In some embodiments, the elongated members can include a series of solid elongate members and tubular elongate members, which construction provides one way to control at least some properties of the device, for example, stiffness, torque transmission, flexibility, shape retention, and the like. In yet some additional embodiments, at least one of the elongated members has a recess into which a protrusion of another elongated member may fit.
US08485990B2	Vacuum assisted lancing system with depth controller and method for blood extraction with minimal pain A lancing system can include a device body having a lancing end, a lancing mechanism including a lancing shaft slideably coupled with the lancing end of the body, a main shaft slideably coupled with the body and having an actuating end disposed inside the body, a piston coupled to the main shaft and disposed within the body, a spring coupled to the piston, a release mechanism adapted to selectively couple with the main shaft, and a depth controller removably coupled to the lancing end of the body. A method can include coupling a lance having a needle and a base to the lancing shaft, choosing to use a depth controller having a spacer with a top surface and an opening, engaging a lancing surface with the depth controller, actuating the lancing mechanism, penetrating the lancing surface, and contacting the top surface of the spacer with the base.
US08485989B2	Biopsy apparatus having a tissue sample retrieval mechanism A biopsy apparatus includes a biopsy probe having a biopsy cannula and a sample basket arranged coaxially about a longitudinal axis. The sample basket is movably disposed relative to the biopsy cannula along the longitudinal axis from a tissue harvesting position to a tissue sample retrieval region. The sample basket has a sample notch formed as an elongate recessed region for receiving a tissue sample. A tissue sample retrieval mechanism includes a sample collection tank configured for removable insertion into a sample tank receptacle. The sample tank receptacle permits movement of the sample collection tank in a direction perpendicular to the longitudinal axis and prohibits movement of the sample collection tank in a direction along the longitudinal axis. The sample collection tank is configured to retrieve the tissue sample directly from the sample notch as the sample basket is moving along the longitudinal axis at the tissue sample retrieval region.
US08485984B2	Portable breath collection system for use in breath tests An automatic breath collecting and sampling system, which is preferably carried by the subject, or otherwise kept with him or near him, for the recommended duration of the collection period. The system collects samples in separate switchable containers, either at predetermined time intervals, or in response to an automatic stimulus, which could be related to the breath content itself, or to another physiological signal, such as the subject s pulse rate, breath rate, blood pressure, or temperature, or in response to a signal related to an environmental effect, such as the presence of a strong concentration in the air of a foreign gas, which could be detected by an electrochemical sensor, or manually by the subject after being prompted by the system. After collection of the requisite number of separate containers, they may be detached and sent for analysis or other treatment.
US08485982B2	Apparatus and method for breathing pattern determination using a non-contact microphone A method is provided for analyzing respiration of a subject (20). Using a non-contact microphone (22), a raw signal indicative of airflow sounds of the respiration is generated. The raw signal is analyzed to determine a first set of one or more parameters of the respiration. An algorithm is applied to the first set of parameters to derive a second set of one or more estimated parameters of the respiration that are not generally directly measurable in the raw signal. Other embodiments are also described.
US08485979B2	System and method for monitoring or treating nervous system disorders An implantable neurostimulator device for implantation in a head of a patient includes a housing adapted to be implanted beneath a patient's scalp, and a cardiac monitoring element, a brain monitoring element, and a processor. The processor is configured to receive a cardiac signal from the cardiac monitoring element, identify cardiac events in the cardiac signal, receive a brain signal from the brain monitoring element, identify neurological events in the brain signal, and indicate a relationship between the neurological events and the cardiac events.
US08485978B2	Systems and methods for noninvasively monitoring baroreflex response and nominal blood volume Systems and methods for noninvasively monitoring baroreflex response and nominal blood volume are disclosed herein. Software and methods for evaluating morphological features of a photoplethysmogram (PPG) obtained using a pulse oximeter allow for the affirmative detection and quantification of the baroreflex response from data obtained during orthostatic stress tests, lower body negative pressure chamber tests and treadmill stress tests.
US08485976B2	Ultrasonic diagnostic apparatus Even when a region of interest (ROI) is changed on a frozen image, an elasticity image of ROI after the change can be displayed without executing re-measurement. An ultrasonic diagnostic apparatus 1 has a control unit 110 having a first ROI setting unit 38 and a second ROI setting unit 39. When ROI is set by the first ROI setting unit 38 of the control unit 110, an elasticity information calculating unit 32 sets an area larger than ROI as a calculation area, calculates distortion, elasticity modulus, etc. of a tissue corresponding to each measurement point on a tomographic image of the calculation area, generates elasticity information based on the distortion, the elasticity modulus, etc., and outputs the elasticity information to an elasticity information storing unit 33. The control unit 110 changes the position/size of ROI by the second ROI setting unit 39 under a state that the frozen image is displayed. The elasticity image constructing unit 34 reads the elasticity information corresponding to the changed ROI from the elasticity information storing unit 33, forms an elasticity image of the changed ROI and displays it on an image display unit 26.
US08485975B2	Multi-resolution edge flow approach to vascular ultrasound for intima-media thickness (IMT) measurement A computer-implemented system and method for fast, reliable, and automated embodiments for using a multi-resolution edge flow approach to vascular ultrasound for intima-media thickness (IMT) measurement. Various embodiments include receiving biomedical imaging data and patient demographic data corresponding to a current scan of a patient; checking the biomedical imaging data in real-time to determine if an artery of the patient has a calcium deposit in a proximal wall of the artery; acquiring arterial data of the patient as a combination of longitudinal B-mode and transverse B-mode data; using a data processor to automatically recognize the artery; using the data processor to calibrate a region of interest around the automatically recognized artery; automatically computing the weak or missing edges of intima-media and media-adventitia walls using edge flow, labeling and connectivity; and determining the intima-media thickness (IMT) of an arterial wall of the automatically recognized artery.
US08485973B2	System and method for tagging and detecting surgical implements A system and method for detecting a surgical implement retained within a surgically exposed human body cavity, includes a tag adapted to be attached to a surgical implement insertable within a human body cavity, including a receiver for receiving an electromagnetic signal and converting it into electric signal; and a circuit to impress said electric signal on the internal human (or an animal) body where the medical product is used; and a transmitter to transmit the electromagnetic signal; and a detector including a receptor for receiving the electric signal from the body and a detector connected to the receptor for detecting the electric signal. The envelope of the induced RF wave is demodulated, thus allowing the voltage at the output to vary at a significantly lower frequency. In the event such pulses are sensed, a sensory alert is actuated.
US08485971B2	Surgical hand access apparatus A surgical access apparatus adaptable to permit the sealed insertion of either the surgeon's hand and/or surgical instruments during laparoscopic and endoscopic surgical procedures includes an access housing defining a longitudinal axis and having a first internal passageway configured and dimensioned to permit passage of at least one of a hand and an arm of a surgeon, and a base mountable to the access housing. The base may include a liner member positionable within an incision of a patient to at least partially line the incision. A displacement member may be operatively connected to the access housing and to the liner member. The displacement member is adapted for movement to cause corresponding displacement of the liner member relative to the access housing whereby the liner member engages tissue forming the incision to at least partially retract the incision.
US08485969B2	Medical guide element with diameter transition Improved medical filaments for use with dilators to be inserted into a patient, for example into the vascular lumen, are provided, as well as combinations of filaments and dilators. Methods for use of such filaments and filament-dilator combinations are also described. The filament includes a proximal segment and a distal segment. The diameter of the distal segment is greater than the diameter of the proximal segment. The change in diameter is abrupt, providing a discrete step transition at a point along the filament which presents a proximally-facing surface on the distal segment. When the proximal segment of the filament is fully inserted into a dilator having a distal tip adapted for insertion into a patient, the dilator distal tip firmly abuts the proximally-facing end surface of the distal segment. The relative dimensions of the dilator tip and the discrete stepped transition of the filament provides full shielding or over shielding of the dilator tip, thereby facilitating passage of the dilator tip along the tissue track, through the puncture hole and into the orifice.
US08485964B2	Gastric band with supply tube check valve A balloon-type gastric band includes a balloon shaped and dimensioned to circumscribe the stomach at a predetermined location. The balloon includes a longitudinally extending body. A supply tube is secured to the balloon for fluid communication with an internal cavity of the balloon, wherein the supply tube includes a valve controlling the flow of fluid to and from the balloon.
US08485961B2	Impeller housing for percutaneous heart pump Disclosed herein are heart pumps that include a catheter assembly and that can be applied percutaneously. Some embodiments include a locking device that prevents components of the catheter assembly from being separated when in use. The catheter assembly can include an expandable tip. In some embodiments, the catheter assembly includes a housing having a wall structure, a portion of which can have a bulbuous shape or can be deformable. In other embodiments, the housing can be configured to reduce fluttering or deflection of the housing and/or to maintain a gap between the housing and an impeller blade disposed therein.
US08485956B2	System for bifolding an absorbent article A system is provided for bifolding disposable absorbent articles on a high speed production line on which the disposable absorbent articles are moved along a predetermined path. The system includes the use of one or more vacuum conveyor assemblies to engage and transfer the leading end portion of the article from the surface of a peel-roll to a folding drum. Thereby potentially reducing the occurrence of undesirable misalignment between opposing edges of an article during a bifolding process.
US08485955B2	Automatic bag handling method for precisely securing a plastic handle to a plastic bag An automatic handle attaching method for precisely securing a plastic handle on an edge of a preformed plastic bag is described. A delivery conveyor for conveying spaced-apart groups of flat plastic bags with each group having two or more bags disposed one on top of the other and offset along a leading straight edge thereof which is oriented approximately transverse to a conveying direction of a conveyor. A bag handling mechanism has an orientable bag engaging hand secured to an articulated arm to orient the bag engaging hand in alignment with a top one of the groups of bags to transfer the bag to a handle securing station where the bag handle is welded thereto. After the handle is welded its relationship with respect to other parts of the bag is verified.
US08485951B1	Vehicle mounted multi-position resistance tube exercise apparatus A vehicle-mounted multi-position pulley-based resistance tube exercise apparatus having resistance tube length effectively doubled for increased range of consistent resistance, and having a height adjustable pulley assembly providing a user with the ability to set multiple exercise initiation points so as to provide exercise options for a full body workout at a single exercise station.
US08485950B2	Multi-position resistance tube exercise apparatus A wall-mounted multi-position pulley-based resistance tube exercise apparatus having resistance tube length effectively doubled for increased range of consistent resistance, and having a height adjustable pulley assembly providing a user with the ability to set multiple exercise initiation points so as to provide exercise options for a full body workout at a single exercise station.
US08485948B2	Fitness equipment The invention discloses a fitness equipment which comprises a ring-shaped gravity body and a handle connected with the gravity body, wherein, the handle is positioned in the radial position of the interior of the ring-shaped gravity body, the end parts of the handle are detachably and fixedly connected with the gravity body, protective covers are embedded into the inner surface of the ring-shaped gravity body, and through the coverage of the protective covers, the connecting parts between the ring-shaped gravity body and the handle are rendered smooth. Through the application of the protective covers and the appropriate structural design of the two end parts of the handle, the surfaces of the fitness equipment provided by the invention can be rendered smooth, thereby effectively avoiding injuries to users.
US08485945B2	Fully adjustable integrated exercise workstation An exercise workstation comprises a table assembly having a working surface, and an elliptical trainer. The elliptical trainer comprises a seat, and at least two footplates capable of elliptical motion about an axis having a horizontal component of motion greater than a vertical component of motion. A first distance between the seat and the table assembly is adjustable, a second distance between the seat and the axis is adjustable, the first distance and the second distance are independently adjustable, and the elliptical trainer is a recumbent or semi-recumbent elliptical trainer.

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