Document Document Title
US08193802B2 Slidably attachable non-contact voltage detector
The invention provides a non-contact voltage detector (“NCVD”) that includes a housing, a power switch, and an LED flashlight. The housing includes an upper portion and a lower portion which are slidably attachable to one another. A voltage sense circuit is positioned within the housing and illuminates a voltage sense indicator when it detects an AC voltage. The power switch is operable to activate the voltage sense circuit and the LED flashlight. The NCVD includes a first set of rails and a second set of rails for slidably attaching the NCVD to a test and measurement device, such as a digital multimeter (“DMM”) or an infrared (“IR”) temperature gun.
US08193798B1 Buck regulators with adjustable clock frequency to achieve dropout voltage reduction
A method includes generating a drive signal for a transistor in a switching regulator. The drive signal turns the transistor on and off to generate a regulated output voltage. The drive signal is generated based on a clock signal. The method also includes dynamically decreasing a frequency of the clock signal to decrease a dropout voltage of the switching regulator. Dynamically decreasing the frequency of the clock signal can increase a duration of switching periods defined by the clock signal. The dropout voltage could have a first value proportional to TOFF—MIN/TON—MAX during shorter switching periods and a second value proportional to TOFF—MIN/TON—MAX—DFC during longer switching periods. TOFF—MIN represents a minimum amount of off-time for the transistor during each switching period, TON—MAX represents a maximum amount of on-time for the transistor during shorter switching periods, and TON—MAX—DFC represent a maximum amount of on-time for the transistor during longer switching periods.
US08193793B2 DC-DC converter
Provided is a DC-DC converter comprising: a drive switching element so that a current flows to an inductor, the drive switching element being driven by a PWM control pulse or a PFM control pulse, wherein a direct-current input voltage supplied from a direct-current power source is converted so as to output the converted direct-current voltage having a different potential, and wherein a PWM control is performed when a load is larger than a predetermined value and a PFM control is performed when the load is smaller than the predetermined value, the DC-DC converter further comprising: a pulse width regulation section to regulate the PWM control pulse so as not to have a pulse width smaller than a predetermined pulse width, at least when the PFM control is switched to the PWM control.
US08193781B2 Harnessing power through electromagnetic induction utilizing printed coils
Systems for harnessing power through electromagnetic induction utilizing printed coils are provided. A system can include one or more moveable magnets adjacent to printed coils on a circuit. For example, a system can include one or more magnets that are operative to move alongside a circuit board that includes printed coils. The one or more magnets may move, for example, when a user shakes the system or when the user walks or runs while holding the device. The movement of the one or more magnets may create an electromotive force (e.g., a voltage) across the printed coils, and this force may be used to generate electric power.
US08193780B2 System and method of charging a battery using a switching regulator
In one embodiment the present invention includes a system and method of charging a battery using a switching regulator. In one embodiment, a switching regulator receives an input voltage and input current. The output of the switching regulator is coupled to a battery to be charged. The switching regulator provides a current into the battery that is larger than the current into the switching regulator. As the voltage on the battery increases, the current provided by the switching regulator is reduced. The present invention may be implemented using either analog or digital techniques for reducing the current into the battery as the battery voltage increases.
US08193767B2 Power receiving device, and electronic apparatus and non-contact charger using the same
Disclosed is an electronic apparatus (1) comprising a power receiving device (2) and an electronic apparatus main body (3). The power receiving device (2) comprises a power receiving coil (11) having a spiral coil, a rectifier (12) and a secondary battery (13). The electronic apparatus main body (3) comprises an electronic device (14) and a circuit board (15). A magnetic foil (16) is arranged in at least one position between the spiral coil (11) and the secondary battery (13), the rectifier (12), the electronic device (14) or the circuit board (15). The magnetic foil (16) has a value expressed as the product of the saturation flux density MS and the thickness t, namely Ms·t, of not less than 15.
US08193762B2 Battery charging apparatus of a wireless digital X-ray detector
Systems, methods and apparatus are provided through which in some implementations a portable wireless digital X-ray detector includes a battery electrically coupled to at least one external electrical conductor. In some implementations, the external electrical conductor is mounted flush to an outside of a housing of the portable wireless digital X-ray detector. In some implementations, the external electrical conductor plate includes only hypoallergenic materials. In some implementations, the battery is fixed mounted in the portable wireless digital X-ray detector. In some implementations docking detector receptacle at least one external electrical conductor in a pocket of the docking detector receptacle.
US08193760B2 Portable cart for solar energy conversion
A portable cart for solar energy conversion is provided comprising a cart having at least two wheels, wherein the cart includes a frame having a floor, a panel receiving assembly, and a panel holding assembly. The panel holding assembly is removably attachable to the panel receiving assembly. One or more photovoltaic solar panels is attached to the panel holding assembly; and voltage generated from the panels is directed to a charge controller. Electrical energy is stored in one or more batteries within the cart. The direct current from the batteries is directed to at least one inverter for producing AC power. An external stand is provided to mount the solar panels at a distance away from the cart. The external stand includes at least two positions to account for the position of the sun across the seasons. Optionally, the cart includes a charging receptacle for receiving a DC charge from an external source, such as an automobile.
US08193759B2 Remote control with solar-powered battery
A remote control with a solar-powered battery, a remote body includes the control panel. The control panel has a plurality of buttons. The solar-powered battery module is disposed in the remote and comprises the solar panel, the control unit and the storage unit. The solar panel is a rigid or flexible solar panel and is used for receiving light energy. The wireless control module disposed in the remote comprises the transmitting unit, the sensing unit and the activating unit. Therefore, the solar-powered battery module converts and stores the light energy and provides power to the wireless control module, thereby providing energy savings and environmental conservation benefits.
US08193757B2 Photovoltaic circuit
A photovoltaic circuit configured to supply an output current to a tank module is provided. The photovoltaic circuit comprises a photovoltaic transformation module, a first process module, a plurality of second process modules, and a first control module. The process modules are connected to each other in parallel. The process modules in the parallel connection are connected to the photovoltaic transformation module and the tank module in series. The first control module is connected to the first process module and generates a control signal to the process modules in response to a divided current, a modulation current, and a last output current generated by the first process module. Thereby, the process modules interlacedly output the corresponding modulation current as the output current supplied to the energy reserve module.
US08193754B2 Mechanical stepper motors
A method for stepping a first member relative to a second member. The method including: providing one of the first and second members with one of a plurality of pockets and movable pins offset from each other with a first spacing; providing the other of the first and second members with the other of the plurality of pockets and movable pins offset from each other with a second spacing, where the first spacing is different from the second spacing; and engaging at least one of the movable pins into a corresponding pocket to step one of the first and second members a predetermined linear and/or rotary displacement.
US08193748B2 Integrated brushless DC motor and controller
An integrated brushless DC motor and controller including a brushless DC motor having a rotating shaft with a 2 pole permanent magnet affixed to the shaft for rotation thereby in a plane orthogonal to the axis of rotation of the shaft. An X-Y Hall Effect Sensor is carried by a controller mounted on a circuit board attached to the motor and the Hall Effect Sensor is positioned proximate the magnet with the Hall Effect Sensor producing the Sine and Cosine components of the magnetic field as the magnet is rotated by the motor shaft. The electronic controller includes software for determining the motor angle and commutation logic from the Sine and Cosine components generated by the Hall Effect Sensor response to the rotating magnetic field. A controller on the board positioned over the rotating shaft contains the highly integrated functions of internal analog digital converters, pulse width modulation registers for driving the power amplifier, internal communication ports and all of the random excess memory and FLASH non-volatile memory that is typically required for motor control.
US08193744B2 Method and apparatus for quiet fan speed control
A method for controlling the speed of an AC motor by means of an AC motor speed control having a plurality of capacitors operable to be selectively coupled in parallel electrical connection, the parallel coupled capacitors operable to be coupled in series electrical connection with the AC motor, the method comprising charging the capacitors up to substantially the same predetermined voltage prior to combining the capacitors in parallel electrical connection.
US08193742B2 Programmable motor for window coverings
An architectural window covering having a programmable electric motor is disclosed. The architectural window covering includes a head rail comprising at least one cavity, a shade coupled to the head rail, a bottom rail coupled to the shade, and at least two tandem stacked motors coupled to the shade via a drive rail such that the at least two motors fit within the at least one cavity of the head rail.
US08193740B2 Controller for discharge lamp and light source device
A control circuit for a discharge lamp, which can improve the lighting performance of the discharge lamp while realizing low power consumption, and a light source device are provided. The resistance value of the variable resistor (RC1, RC2) is not switched to the low resistance (R02) for steady discharge at the fourth time t4, but is switched to the low resistance (R02) at the fifth time t5, after lowering of power supply to the filament. With such control, a change in the lamp impedance is absorbed sufficiently by the variable resistor while power supply to the filament is being lowered and, therefore, destabilization of discharge is reduced and the lighting performance is improved.
US08193739B2 Apparatus for lighting LEDs
An apparatus for lighting LEDs includes an LED group load having the LEDs, a converter to generate a voltage applied to the LED group load, a current controller to control a current of the LED group load, a voltage controller to control an output voltage provided by the converter, a time division circuit to intermittently pass a current through the LED group load, and a selector. The selector, during a period in which the time division circuit passes a current through the LED group load, selects the current controller to control a current of the LED group load and thereby control an output voltage provided by the converter, and during a period in which the time division circuit passes no current through the LED group load, selects the voltage controller to control an output voltage provided by the converter.
US08193737B2 Color manager for backlight systems operative at multiple current levels
A color manager for use with a luminaire constituted of a plurality of different colored light emitting diode based sub-luminaires arranged to produce a combined light. The color manager is constituted of a sampler arranged to output an electrical representation of the optical output of the luminaire, a converter coupled to the output of said sampler and operatively associated with a current selector arranged to select the driving current level of the luminaire from a plurality of current levels. The converter is arranged to convert said electrical representation to a pre-determined calorimetric system in cooperation with a calibration matrix whose values are selected responsive to the selected driving current level. The color manager further comprises a driver operatively associated with the luminaire, the converter and current selector and arranged to drive the luminaire in accordance with the driving current level as selected by the selector.
US08193733B2 LED driver circuit
A novel LED driver circuit, including: a current regulation circuit, having a first end and a second end, wherein a first current is flowing into the second end, and a voltage difference between the first end and the second end is generated in response to the first current; a transistor, coupled with the first end and second end of the current regulation circuit; a bias network, having a first end and a second end, the second end being coupled with the transistor; and a LED module, having at least two connection nodes, wherein the connection node at one end of the LED module is coupled to a line voltage, the connection node at the other end of the LED module is coupled to the transistor, and one of the at least two connection nodes is coupled with the first end of the bias network.
US08193732B2 Automatic calibration of an automated dimmer
The present specification discloses a method and device for automatically calibrating a reference light level for an automated dimmer for electric lights, such as fluorescent lamps. An automatic dimmer, including an automatic calibration device, can be installed in series between an instant-start electronic ballast and a fluorescent lamp. An exemplary method for calibrating a lamp includes blocking or removing all ambient light, turning on the electric light, measuring the light output, and turning off the electric light.
US08193730B2 Dimmer and illumination apparatus with amplitude ordered illumination of multiple strings of multiple color light emitting devices
A dimmer and an illumination apparatus are connected by a two wire circuit. The dimmer energizes the illumination apparatus and provides control of the illumination apparatus via the two wire circuit. The illumination apparatus receives all of its energization and control from the two wire circuit. Multiple strings of multiple color light emitting devices are switched on in a partitioned order during flank intervals of a switched AC power envelope on the two wire circuit.
US08193729B2 Wireless remote control system and methods for monitoring and controlling illuminating devices
A system includes first and second illuminating devices respectively having different first and second identification numbers indicative of locations and/or serial numbers of the illuminating devices. A parameter of one of voltage, temperature, resistance, and power of a lighting unit of each illuminating device is detected. The parameter and the identification number of each illuminating device are encoded into a packet. The second illuminating device receives the packet of the first illuminating device and sends the packets of the first and second illuminating devices to a control center. The control center decodes the packets and judges operational states of the illuminating devices based on the parameters detected. A control signal is sent by the control center to turn on or off or control brightness of at least one of the illuminating devices when at least one of the illuminated devices is judged as operating abnormally after judging the parameters detected.
US08193728B2 Circuit arrangement and method for operating a high-pressure discharge lamp
A circuit arrangement for operating a high-pressure discharge lamp, comprising at least one first electronic switch and one second electronic switch in a half-bridge arrangement; a supply voltage terminal for supplying the half-bridge arrangement with a DC voltage signal; a load circuit, which comprises a lamp inductor and is coupled firstly to the half-bridge center point and secondly to at least one terminal for connecting the high-pressure discharge lamp; a drive circuit for providing at least one first and one second drive signal for the first electronic switch and the second electronic switch, the drive circuit being adapted to provide the first and the second drive signal in such a way that the clock thereof is firstly swept between a first and a second frequency; wherein the drive circuit is furthermore adapted to modulate the first and the second drive signal with a predeterminable third frequency, with the modulation with the predeterminable third frequency being single-tone frequency modulation, with the result that, in the amplitude spectrum of the first and the second drive signal, at least one first, one second and one third spectral line appear, the first spectral line corresponding to the instantaneous frequency of the swept clock, and the second and the third spectral lines, in terms of absolute value, appearing at an interval with respect to the predeterminable third frequency, symmetrically with respect to the first spectral line, and that, in the power spectrum of the signal, at the terminal for connecting the high-pressure discharge lamp, a spectral line at the predeterminable third frequency results.
US08193727B2 Lamp end of life protection circuit and method for an electronic dimming ballast
A electronic ballast includes an inverter circuit for converting a DC voltage into a high-frequency voltage, a resonant circuit connected between outputs of the inverter circuit so as to light a discharge lamp by a resonant action, a control circuit for controlling the inverter circuit, a dimming circuit for continuously changing an output voltage to the discharge lamp by changing an operation frequency in the inverter circuit, a DC component detection circuit and a voltage comparator for detecting whether or not the discharge lamp is at the end of the life at predetermined intervals and outputting an end of life detection signal upon detection of the end of the life state, and a frequency control circuit and a driving circuit for reducing or stopping an output to the discharge lamp by controlling switching elements in response to a life end detection signal inputted from the voltage comparator.
US08193726B2 Fluorescent light temperature sensor
A fluorescent light temperature sensor for producing a temperature signal from a fluorescent light of an optically stimulated fluorescent material is provided with: an LED for projecting light onto the fluorescent material; a driving circuit for driving the light projecting element; a photo diode for receiving the fluorescent light that is emitted from the fluorescent material; a signal processing circuit for producing the temperature signal from the output signal from the photo diode; and an APC circuit for controlling the driving of the driving circuit so as to maintain a uniform light projecting intensity from the LED based on the output signal of the photo diode.
US08193723B2 LED current-balance driving circuit
An LED current-balance driving circuit for driving a plurality of LED strings comprises a feedback transformer, a plurality of current-balance transformers, a plurality of full-wave rectifiers and a current control circuit. The feedback transformer has a detecting winding and an outputting winding for outputting a feedback signal. Each of the current-balance transformers has a primary winding and a secondary winding. The primary windings of the current-balance transformers and the detecting winding of the feedback transformer are coupled in series to compose a current-balance loop with an AC power being supplied thereto. Each of the full-wave rectifiers is coupled between a corresponding secondary winding of the current balance transformers and a corresponding LED string of the LED strings. The current control circuit receives the feedback signal and controls the AC power according to the feedback signal.
US08193722B2 Circuit arrangement having a transformation apparatus and operating method for a lamp using a circuit arrangement having a transformation apparatus
The present invention relates to a circuit arrangement having a transformation apparatus, which has a primary side (P) and a secondary side (S), wherein the primary side and the secondary side (S) are DC-isolated from one another, wherein the primary side (P) has a terminal for a supply voltage (UE) and is connected to a first reference potential, wherein the secondary side (S) comprises a first and a second output line, which, in the normal case, are not coupled to a reference potential and which form an output terminal, at which a voltage for a load (LA) can be provided, wherein it furthermore comprises: an apparatus for tapping off a measured voltage potential (CP) on the secondary side (S); and an apparatus (10) for determining whether the measured voltage potential is in a permissible range. The invention moreover relates to an operating method for a lamp using a circuit arrangement.
US08193720B2 Electrodeless lamp protecting device
An electrodeless lamp protecting device installed between an electrodeless lamp and a power source comprises a substrate having a feedback signal input module, a signal level determination module and a protection signal output module installed on the substrate. A signal of the power source is transmitted from the feedback signal input module to the signal level determination module, and the signal serves as a reference for an output signal of the protection signal output module, such that the electrodeless lamp has an automatic protection function upon the receipt of an abnormal signal.
US08193718B2 Diagnosis circuit apparatus and lamp ballast circuit using the same
The present invention relates to a diagnostic device and a lamp ballast circuit. The lamp ballast circuit includes a first power switch, a second power switch, a lamp driven according to switching operations of the first and second power switches, a controller for controlling the switching operations of the first and second power switches, and a diagnostic device. The diagnostic device senses a voltage waveform applied to the lamp to determine an end of lamp life (EOLL) condition and an over-voltage, senses a filament voltage of the lamp to determine a filament connection state of the lamp, and determines an over-voltage of a voltage applied to the controller.
US08193714B2 Light-emitting device including light-emitting thyristor array, light-emitting element chip including light-emitting thyristor array and light emission adjusting method for a light-emitting thyristor array
The light-emitting device includes: a setting unit switching a potential difference between anode and cathode electrodes alternately between first and second potential differences so that light-emitting thyristors are caused to have one of the first and second potential differences in common; a specifying unit sequentially specifying, as a target for controlling, one light-emitting thyristor; a supply unit alternately supplying transition voltage for causing specified light-emitting thyristor to transition from the off state to the on state and maintaining voltage for keeping the thyristor being in the off state to a gate electrode of the thyristor, in a light-emission control period during which the specifying unit specifies the target and the setting unit sets the second potential difference; and an adjusting unit that adjusts a light-emitting period of the one light-emitting thyristor by supplying the maintaining voltage and stopping supplying the voltage at a variable timing, in the light-emission control period.
US08193713B2 Apparatus and a method comprising illumination lighting fixture and sensor
One aspect relates to combining an at least one primary general illumination lighting with an at least one LED-based secondary general illumination lighting. The aspect further comprises sensing an at least one sensed electric characteristics used to produce the at least one primary general illumination lighting. The aspect further comprises controlling an optical characteristic of the at least one LED-based secondary general illumination lighting at least partially responsive to the sensing the at least one sensed electric characteristics used to produce the at least one primary general illumination lighting.
US08193711B2 Metal halide lamp
A metal halide lamp is comprised of an airtight tube having a discharge section in which a discharge space is formed; a discharge medium which is enclosed in the discharge space, contains metal halide exhibiting a molar ratio of sodium halide to scandium halide of 1.5 or below and 8 atm or higher of xenon but does not substantially contain mercury; and a pair of electrodes with their tip ends arranged to oppose to each other in the discharge space, wherein halogen atoms bonded to metal in the metal halide mostly consist of iodine and bromine atoms, and a ratio of the bromine atoms is in a range of 10 to 50% and the total amount of the metal halide enclosed is 0.02 mg/μl or less.
US08193707B2 Conductive composition for black bus electrode, and front panel of plasma display panel
The black bus electrode of plasma display panel is formed from a conductive composition comprising a conductive powder, glass powder, organic binder, organic solvent, and black pigment, wherein the conductive powder is platinum particle or gold particle.
US08193704B2 Perovskite oxide thin film EL element
There are provided a perovskite oxide thin film EL element in which a hole transport layer/a light-emitting layer/an electron transport layer comprising a perovskite oxide thin film are formed on a lower electrode, and an upper electrode is formed thereon, and a perovskite oxide thin film EL element that provides red light emission in the vicinity of a wavelength of 610 nm, which is the basis of display making. A perovskite oxide thin film EL element comprising a lower electrode 1 comprising a polished single crystal substrate, an electron transport layer 2 comprising a perovskite oxide thin film, which is a dielectric, formed on the lower electrode 1, a light-emitting layer 3 comprising a perovskite oxide thin film formed on the electron transport layer 2, a hole transport layer 4 comprising a perovskite oxide thin film, which is a dielectric, formed on the light-emitting layer 3, a buffer layer 5 formed on the hole transport layer 4, and a transparent upper electrode 6 formed on the buffer layer 5.
US08193698B2 Organic light emitting diode and method for producing an organic light emitting diode
An organic light-emitting diode includes an organic light-emitting layer located between a transparent electrode and one other electrode on a substrate. In some embodiments at least one of the transparent electrode and the other electrode has two layers. The two layers include a structured layer, which is a charge carrier injection layer, and a conductive second layer into which the first layer is embedded. In some embodiments the organic light-emitting layer includes a structured charge carrier blocking layer.
US08193695B2 Organic light emitting device and manufacturing method thereof
The present invention relates to an organic light emitting device and a manufacturing method thereof. A method of manufacturing an organic light emitting device according to an exemplary embodiment of the present invention includes: respectively forming first, second, and third driving transistors in a first region, a second region, and a third region on a substrate; forming an insulating layer on the first to third driving transistors; respectively forming first, second, and third pixel electrodes on the insulating layer, the first, second, and third pixel electrodes being formed in the first, second, and third regions, respectively; forming an auxiliary electrode on a side surface of each of the first, second, and third pixel electrodes; forming an organic light emitting member on the first to third pixel electrodes; and forming a common electrode on the organic light emitting member.
US08193683B2 Low power continuous wave ultrasound transmitter
A system and method for providing a continuous wave (“CW”) ultrasonic drive signal and a B-mode ultrasonic drive signal from an ultrasonic transmitter are disclosed herein. An ultrasonic transmitter includes a first shunt transistor and a second shunt transistor. The first shunt transistor shunts positive transmitter output voltage to ground. The second shunt transistor shunts negative transmitter output voltage to ground. The shunt transistors include control inputs that, when modulated, cause the shunt transistors to produce a CW ultrasonic drive signal on a transmitter output. The ultrasonic transmitter also includes a first CW control transistor coupled to the first shunt transistor, and a second CW control transistor coupled to the second shunt transistor. The first and second CW control transistors respectively provide negative and positive CW drive voltage to the first and second shunt transistors.
US08193676B2 Coil manufacturing method and coil manufacturing apparatus
A coil manufacturing method for manufacturing a wave wound coil in a substantially cylindrical shape by shaping a linear conductor with a cross-sectional shape having directionality, including: transferring a linear waver conductor shaped in a substantially rectangular waveform, and having straight side portions extending in a wave width direction, one-side connecting portions sequentially connecting every other pair of adjacent side portions at ends on a one wave width direction side, and other-side connecting portions sequentially connecting pairs of adjacent side portions that are not connected by the one-side connecting portions at ends on an other wave width direction side; bending a target connecting portion, which is at least one of the one-side connecting portions and the other-side connecting portions of the wave conductor, at one position thereof to shape the target connecting portion into a substantially V shape so that the side portions are arranged along a coil circumferential direction and directions of cross-sectional shapes of the side portions are in a constant direction with respect to a coil radial direction; and winding the bent wave conductor on a bobbin.
US08193670B2 Magnetorheological actuators
Provided is an actuator, comprising a motor/generator element and a clutch/brake element. The motor/generator element comprises a stator made of a high magnetic permeable material, an outer coil being wound around the stator; a rotor made of a high magnetic permeable material and with a plurality of permanent magnets fixed thereon; and a cavity configured to receive a fluid. The clutch/brake element is arranged in the cavity. An inner coil is wound around the clutch/brake element. The fluid is capable of producing a shear stress in response to an electromagnetic field induced from the inner coil.
US08193668B2 Motor with speed reduction mechanism capable of absorbing axial deviation between armature shaft and worm shaft
Detecting a rotation state of a worm wheel side with good accuracy while allowing play between an armature-shaft-side coupling member and a worm-shaft-side coupling member. The armature-shaft-side coupling member is provided together rotatably to the other end of an armature shaft; the worm-shaft-side coupling member is provided together rotatably to one end of a worm shaft; the armature-shaft-side coupling member and the worm-shaft-side coupling member are coupled together rotatably; and a sensor magnet is provided together rotatably to the worm-shaft-side coupling member. Therefore, the rotation state of the worm shaft can be detected with good accuracy. Even if the play is provided between the armature-shaft-side coupling member and the worm-shaft-side coupling member, this play does not affect the accuracy of detection of the rotation state of the worm shaft, thereby bringing no problem regarding accuracy of detection of a rotation state of a worm wheel side.
US08193665B2 Multi-protocol fire-alarm strobe synchronization
A system and method of synchronization protocol for fire alarm strobe systems which has the ability to synchronize the strobe light devices from different manufactures simultaneously.
US08193663B2 Information processing apparatus with multiple power receiving units
An information processing apparatus is provided that has a processor for performing an information processing, a power supply unit for receiving an external electric power from an external electric power source and for supplying the external electric power to the processor, a first power receiving unit connected to a first communication medium, the first power receiving unit receiving a first electric power from the first communication medium and supplying the first electric power to the processor, a second power receiving unit connected to a second communication medium, the second power receiving unit receiving a second electric power from the second communication medium and supplying the second electric power to the processor, an electric power detection unit for detecting the first electric power or the second electric power, and a switching unit for supplying one of the external electric power, the first electric power, and the second electric power to the processor according to a result of detection made by the electric power detection unit.
US08193660B2 HVAC/R system having power back-up system with a DC-DC converter
An HVAC/R system is configured with power storage for power back-up to maintain substantially uninterrupted power in the case of a main power failure. The power back-up system has a DC power source configured to be recharged, and provides power to the HVAC/R components.
US08193659B2 Power system
A power system is provided for delivering a custom level of electrical power to an industrial or commercial facility, comprising a local generator connected to a turbine operating in accordance with an organic Rankine cycle, the local generator having a capacity at least greater than a maximum anticipated power level needed for the electrical needs of a local industrial or commercial facility, one or more control devices operatively connected to the local generator for regulating active and reactive power generated by the generator, a detector for sensing active voltage induced by said generator, a detector for sensing reactive voltage produced by the generator, and a controller in electrical communication with said one or more control devices and with the active and reactive voltage detectors, wherein the controller directs the one or more control devices to regulate the generator such that the active power and reactive power generated by the generator are sufficient to satisfy active and reactive load conditions, of local industrial or commercial facilities. The present invention is also directed to a power system for providing a fast acting spinning reserve, comprising a turbine module of a organic Rankine cycle that is coupled to a generator, a main conduit through which motive fluid heated in said thermodynamic cycle is delivered to the turbine module, and a flow control component operatively connected to said main conduit for automatically limiting the flow of the motive fluid to the turbine module during base load conditions and for automatically increasing the flow of the motive fluid to the turbine module during variable load conditions.
US08193656B2 Water and wind current power generation system
An apparatus using differential gearboxes to collect, combine, and transmit torque generated by multiple, interconnected rotor systems. The rotor systems are connected via a driveshaft. The driveshaft is connected to a generator gearbox, and the generator box drives an electrical generator. The torque may be converted to mechanical power by replacing the electrical generator with a mechanical power device. The rotors are activated by fluid currents such as wind or water.
US08193652B2 Reversible hydroelectric device
Reversible hydroelectric device that can be installed on an outside pipe, comprising a hydraulic power unit comprising a hydraulic machine comprising a centrifugal pump that can be reversed as a turbine and a hydraulic circuit having bypass branches and motorized valves allowing circulation of water in said hydraulic machine in one direction or the other irrespective of the direction of circulation of the water in said outside pipe; an electric machine coupled to said hydraulic machine and comprising an asynchronous motor that can be reversed as an asynchronous generator; and an electronic system comprising a programmable controller for adjusting and/or regulating said valves and an electronic variator for adjusting and/or regulating the rotation speed of said electric machine so that the pressure and/or flow rate downstream of the hydraulic machine depending on the direction of circulation is/are stabilized or adjusted to at least one set point value.
US08193650B2 Power generation system for a stroller
A system for generating electrical energy from the movement of the stroller includes: a wheel; a gear reduction system operationally coupled between the wheel and a motor such that rotation of the wheel causes the motor to generate electrical energy; a power storage device operationally coupled to the motor for storing the electrical energy produced by the motor; and a control system. The control system includes: a switching device operationally coupled between the motor and the power storage device; and a microcontroller operationally coupled to the switching device and configured to control the state of the switching device. The microcontroller controls the switching device to close to allow the electrical energy generated by the motor to flow into and charge the power storage device, and the microcontroller controls the switching device to open to prevent the electrical energy from flowing to the power storage device.
US08193649B2 Substrate for a display panel, and a display panel having the same
A substrate for a display panel includes an alignment accuracy measurement mark which is used for measuring alignment accuracy between patterns on the substrate without decreasing an aperture ratio of a pixel. The substrate for a display panel includes the alignment accuracy measurement mark in an isolated configuration which is used for measuring alignment accuracy between a pattern of a gate signal line and an auxiliary capacitance line and a pattern of a source signal line and a drain line, where the alignment accuracy measurement mark has a shape such that at least one straight line portion is included, is formed in a layer where the pattern of the source signal line and the drain line is formed, and is positioned on the gate signal line.
US08193646B2 Semiconductor component having through wire interconnect (TWI) with compressed wire
A semiconductor component includes a semiconductor substrate having a substrate contact, and a through wire interconnect (TWI) bonded to the substrate contact. The through wire interconnect (TWI) includes a via through the substrate contact and the substrate, a wire in the via bonded to the substrate contact, and a contact on the wire. A stacked semiconductor component includes the semiconductor substrate, and a second semiconductor substrate stacked on the substrate and bonded to a through wire interconnect on the substrate. A method for fabricating a semiconductor component with a through wire interconnect includes the steps of providing a semiconductor substrate with a substrate contact, forming a via through the substrate contact and part way through the substrate, placing the wire in the via, bonding the wire to the substrate contact, and then thinning the substrate from a second side to expose a contact on the wire. A system for fabricating the semiconductor component includes a bonding capillary configured to place the wire in the via, and to form a bonded connection between the wire and the substrate contact.
US08193644B2 Pop precursor with interposer for top package bond pad pitch compensation
An electronic assembly adapted for forming package on package (PoP) devices includes a package substrate having a molded IC die thereon that defines a mold cap height and substrate contact pads lateral to the molded IC die. An interposer including an interposer substrate has bottom metal land pads and top metal land pads, interposer vias, and an open receptacle region formed through the interposer substrate. The substrate top surface is positioned relative to the interposer so that the molded IC die is within the open receptacle region to align the bottom metal land pads and substrate contact pads. An underfill layer is between the substrate top surface and the bottom side of the interposer substrate. A step height from the mold cap height minus a height of the top metal land pads is generally from 0 to 0.2 mm.
US08193637B2 Semiconductor package and multi-chip package using the same
A semiconductor package may have a semiconductor chip that includes a chip pad formed on a substrate including an integrated circuit, and a passivation layer exposing the chip pad, a first redistribution wiring layer that is connected to the chip pad and extends on the semiconductor chip and includes a wire bonding pad to provide wire bonding and a first solder pad to connect the first redistribution wiring layer to a second semiconductor chip, and a second redistribution wiring layer that is connected to the first redistribution wiring layer on the first redistribution wiring layer and includes a second solder pad to connect the second redistribution wiring layer to a third semiconductor chip.
US08193636B2 Chip assembly with interconnection by metal bump
A chip assembly includes a semiconductor chip, a bump and an external circuit. The semiconductor chip includes a semiconductor substrate, a transistor in and on the semiconductor substrate, multiple dielectric layers over the semiconductor substrate, a metallization structure over the semiconductor substrate, wherein the metallization structure is connected to the transistor, and a passivation layer over the metallization structure, over the dielectric layers and over the transistor. The bump is connected to the metallization structure through an opening in the passivation layer, wherein the bump includes an adhesion/barrier layer and a gold layer over the adhesion/barrier layer. The external circuit can be connected to the bump using a tape carrier package (TCP), a chip-on-film (COF) package or a chip-on-glass (COG) assembly.
US08193634B2 Mounted semiconductor device and a method for making the same
A method for mounting a semiconductor device onto a composite substrate, including a submount and a heat sink, is described. According to one aspect of the invention, the materials for the submount and the heat sink are chosen so that the value of coefficient of thermal expansion of the semiconductor device is in between the values of coefficients of thermal expansion of the materials of the submount and the heat sink, the thickness of the submount being chosen so as to equalize thermal expansion of the semiconductor device to that of the surface of the submount the device is mounted on. According to another aspect of the invention, the semiconductor device, the submount, and the heat sink are soldered into a stack at a single step of heating, which facilitates reduction of residual post-soldering stresses.
US08193628B2 Printed wiring board, a method of manufacturing printed wiring board, a sensor module, and a sensing device
A printed wiring board on which a package to be arranged, including: a first layer that is relatively rigid; and a second layer that is relatively flexible and on which the package is to be soldered, wherein an area other than a package arrangement area of the second layer is joined to the first layer by an adhesion layer.
US08193626B2 Semiconductor package including multiple chips and separate groups of leads
Provided is a semiconductor package including multiple semiconductor chips, and separate groups of leads connected to the semiconductor chips. The leads are exposed to the outside of the semiconductor package. The plurality of leads may include a first lead group for a first chip group and a second lead group for a second chip group. The first and second chip groups are part of the package.
US08193625B2 Stacked-chip packaging structure and fabrication method thereof
A stacked-chip packaging structure includes chip sets, a heat sink, a substrate, a circuit board, and solder balls. The chip sets are stacked together, each of which has a heat-dissipation structure and a chip. The heat-dissipation structure has a chip recess, through holes arranged in the chip recess, and an extending portion extending from the chip recess. The chip disposed in the chip recess has bumps. Each bump on the chip is correspondingly disposed in one of the through holes of the heat-dissipation structure. The extending portion of the heat-dissipation structure of each chip set contacts that of the neighboring chip set. The heat sink and the substrate are disposed at two opposite sides of the chip sets, respectively. The circuit board is below the substrate. The solder balls are between the circuit board and the substrate.
US08193623B2 Support with integrated deposit of gas absorbing material for manufacturing microelectronic, microoptoelectronic or micromechanical devices
The specification teaches a device for use in the manufacturing of microelectronic, microoptoelectronic or micromechanical devices (microdevices) in which a contaminant absorption layer improves the life and operation of the microdevice. In a preferred embodiment the invention includes a mechanical supporting base, and a layer of a gas absorbing or purifier material is deposited on the base by a variety of techniques and a layer for temporary protection of the purification material is placed on top of the purification material. The temporary protection material is compatible for use in the microdevice and can be removed during the manufacture of the microdevice.
US08193621B2 Semiconductor device
A semiconductor device includes a lead frame including inner lead portion having inner leads connected to outer leads and relay inner leads not connected to the outer leads. A semiconductor element is mounted on a lower surface of the lead frame. Electrode pads of the semiconductor element are connected to the inner lead portion via metal wire. One end of the relay inner lead is connected to the electrode pad via the metal wire, and the other end is connected to the outer lead via a relay metal wire disposed to step over the inner lead.
US08193611B1 High performance InAs-based devices
Material layer structures that have high mobility, a high conduction band barrier and materials that can be implanted to enable higher performance FET device. The structures contain a quantum well layer disposed between two barriers and disposed above a buffer layer and a substrate.
US08193610B2 Semiconductor device and method of forming B-stage conductive polymer over contact pads of semiconductor die in Fo-WLCSP
A semiconductor wafer contains a plurality of semiconductor die with bumps formed over contact pads on an active surface of the semiconductor die. A b-stage conductive polymer is deposited over the contact pads on the semiconductor wafer. The semiconductor wafer is singulated to separate the die. An insulating layer is formed over a carrier with openings formed in the insulating layer. The die is mounted to the carrier with the conductive polymer disposed in the openings of the insulating layer. The conductive polymer is heated to a glass transition temperature to liquefy the conductive polymer to an electrically conductive state. An encapsulant is deposited over the die and insulating layer. The carrier is removed to expose the conductive polymer. An interconnect structure is formed over the die, encapsulant, and conductive polymer. The interconnect structure is electrically connected through the conductive polymer to the contact pads on the die.
US08193609B2 Heterojunction bipolar transistor device with electrostatic discharge ruggedness
A heterojunction bipolar transistor (HBT) device and system having electrostatic discharge ruggedness, and methods for making the same, are disclosed. An HBT device having electrostatic discharge ruggedness may include one or more emitter fingers including an emitter layer, a transition layer formed over the emitter layer, and an emitter cap layer formed over the transition layer.
US08193607B2 Memory cell having GeN-containing material and variable resistance material embedded within insulating material
A variable resistance memory cell structure and a method of forming it. The method includes forming a first electrode, forming an insulating material over the first electrode, forming a via in the insulating material to expose a surface of the first electrode, forming a heater material within the via using gas cluster ion beams, forming a variable resistance material within the via, and forming a second electrode such that the heater material and variable resistance material are provided between the first and second electrodes.
US08193605B2 Bipolar junction transistor integrated with PIP capacitor and method for making the same
A bipolar junction transistor (BJT) integrated with a PIP capacitor includes a substrate including a bipolar junction transistor region and a PIP capacitor region, a bipolar junction transistor disposed in the bipolar junction transistor region and extending an isolation layer to the PIP capacitor region and a base poly layer disposed on the isolation layer, and a PIP capacitor disposed in the PIP capacitor region and including a lower poly layer, the isolation layer and the base poly layer to selectively form a PIP capacitor.
US08193601B2 Structure and method for flexible sensor array
A method of forming a sensor array. The method includes depositing a source/drain contact layer; depositing a semiconductor layer on the source/drain contact layer; and patterning the source/drain contact layer and the semiconductor layer substantially simultaneously, wherein the patterned semiconductor layer forms part of a sensor of the sensor array.
US08193597B2 Acoustic device with low acoustic loss packaging
A device includes: a substrate having an aperture therethrough from a first side of the substrate to a second side of the substrate; a semiconductor die having an acoustic transducer, the semiconductor die being provided on the first side of the substrate such that the acoustic transducer is aligned with the aperture in the substrate; and a dual in-line package having a recess formed therein. The substrate is disposed such that the first side of the substrate faces the recess of the dual in-line package, and the semiconductor die is disposed between the first side of the substrate and the bottom surface of the recess in the dual in-line package.
US08193596B2 Micro-electro-mechanical systems (MEMS) package
A micro-electro-mechanical systems (MEMS) package includes a MEMS microphone device. The MEMS microphone device has a first substrate and at least a sensing element on the first substrate wherein a first chamber in the MEMS microphone device is connected to the sensing element. A second substrate is disposed over the MEMS microphone device to provide a second chamber in the second substrate over the sensing element opposite to the first chamber.
US08193595B2 Method of forming a die having an IC region adjacent a MEMS region
A method that includes forming a first layer having a first dopant concentration, the first layer having an integrated circuit region and a micro-electromechanical region and doping the micro-electromechanical region of the first layer to have a second dopant concentration is presented. The method includes forming a second layer having a third dopant concentration overlying the first layer, doping the second layer that overlies the micro-electromechanical region to have a fourth dopant concentration, forming a micro-electromechanical structure in the micro-electromechanical region using the first and second layers, and forming active components in the integrated circuit region using the second layer.
US08193592B2 MOSFET with asymmetrical extension implant
A method for fabricating a MOSFET (e.g., a PMOS FET) includes providing a semiconductor substrate having surface characterized by a (110) surface orientation or (110) sidewall surfaces, forming a gate structure on the surface, and forming a source extension and a drain extension in the semiconductor substrate asymmetrically positioned with respect to the gate structure. An ion implantation process is performed at a non-zero tilt angle. At least one spacer and the gate electrode mask a portion of the surface during the ion implantation process such that the source extension and drain extension are asymmetrically positioned with respect to the gate structure by an asymmetry measure.
US08193590B2 Interconnecting bit lines in memory devices for multiplexing
An embodiment of a memory device has a plurality of conductive plugs formed on a semiconductor substrate and a pair of successively adjacent first and second bit lines overlying and in contact with each of the conductive plugs.
US08193589B2 Work function based voltage reference
A voltage reference is created from an operational amplifier circuit having two substantially identical P-channel metal oxide semiconductor (P-MOS) transistors with each one having a different gate dopant. The different gate dopants result in different threshold voltages for each of the two otherwise substantially identical P-MOS transistors. The difference between these two threshold voltages is then used to create the voltage reference equal to the difference. The two P-MOS transistors are configured as a differential pair in the operational amplifier circuit and the output of the operational amplifier is used as the voltage reference.
US08193588B2 Semiconductor device
A method for fabricating a semiconductor device comprises: forming a gate pattern over a silicon active region and an insulating layer, which form a semiconductor substrate; removing the silicon active region exposed between the gate patterns; and filling a space between the gate patterns to form a plug.
US08193585B2 Semiconductor device with increased snapback voltage
Methods and apparatus are provided for fabricating a semiconductor device structure. The semiconductor device structure comprises a buried region having a first conductivity type, a first region having a second conductivity type overlying the buried region, a source region having the first conductivity type overlying the first region, and a drain region having the first conductivity type overlying the first region. The semiconductor device structure further comprises a second region having the first conductivity type overlying the buried region, the second region abutting the buried region to form an electrical contact with the buried region, and a first resistance configured electrically in series with the second region and the buried region. The combined series resistance of the first resistance and the second region is greater than a resistance of the buried region.
US08193584B2 Semiconductor component including a drift zone and a drift control zone
A semiconductor component including a drift zone and a drift control zone. One embodiment provides a transistor component having a drift zone, a body zone, a source zone and a drain zone. The drift zone is arranged between the body zone and the drain zone. The body zone is arranged between the source zone and the drift zone.
US08193580B2 Shielded gate trench MOSFET device and fabrication
A semiconductor device embodiment includes a substrate, an active gate trench in the substrate, and an asymmetric trench in the substrate. The asymmetric trench has a first trench wall and a second trench wall, the first trench wall is lined with oxide having a first thickness, and the second trench wall is lined with oxide having a second thickness that is different from the first thickness. Another semiconductor device embodiment includes a substrate, an active gate trench in the substrate; and a source polysilicon pickup trench in the substrate. The source polysilicon pickup trench includes a polysilicon electrode, and top surface of the polysilicon electrode is below a bottom of a body region. Another semiconductor device includes a substrate, an active gate trench in the substrate, the active gate trench has a first top gate electrode and a first bottom source electrode, and a gate runner trench comprising a second top gate electrode and a second bottom source electrode. The second top gate electrode is narrower than the second bottom source electrode.
US08193575B2 Flash memory structure with enhanced capacitive coupling coefficient ratio (CCCR) and method for fabrication thereof
A flash memory structure having an enhanced capacitive coupling coefficient ratio (CCCR) may be fabricated in a self-aligned manner while using a semiconductor substrate that has an active region that is recessed within an aperture with respect to an isolation region that surrounds the active region. The flash memory structure includes a floating gate that does not rise above the isolation region, and that preferably consists of a single layer that has a U shape. The U shape facilitates the enhanced capacitive coupling coefficient ratio.
US08193571B2 Stacked type nonvolatile semiconductor memory device and method of manufacturing same
A stacked body is formed on a silicon substrate by stacking a plurality of insulating films and a plurality of electrode films alternately and through-holes are formed to extend in the stacking direction. Next, gaps are formed between the electrode films using etching the insulating films via the through-holes. Charge storage layers are formed along side faces of the through-holes and inner faces of the gaps, and silicon pillars are filled into the through-holes. Thereby, a nonvolatile semiconductor memory device is manufactured.
US08193568B2 Nanocrystal based universal memory cells, and memory cells
Some embodiments include memory cells that contain a dynamic random access memory (DRAM) element and a nonvolatile memory (NVM) element. The DRAM element contains two types of DRAM nanoparticles that differ in work function. The NVM contains two types of NVM nanoparticles that differ in trapping depth. The NVM nanoparticles may be in vertically displaced charge-trapping planes. The memory cell contains a tunnel dielectric, and one of the charge-trapping planes of the NVM may be further from the tunnel dielectric than the other. The NVM charge-trapping plane that is further from the tunnel dielectric may contain larger NVM nanoparticles than the other NVM charge-trapping plane. The DRAM element may contain a single charge-trapping plane that has both types of DRAM nanoparticles therein. The memory cells may be incorporated into electronic systems.
US08193564B2 Silicon carbide semiconductor device including deep layer
A silicon carbide semiconductor device includes a substrate, a drift layer located on a first surface of the substrate, a base region located on the drift layer, a source region located on the base region, a trench penetrating the source region and the base region to the drift layer, a channel layer located in the trench, a gate insulating layer located on the channel layer, a gate electrode located on the gate insulating layer, a source electrode electrically coupled with the source region and the base region, a drain electrode located on a second surface of the substrate, and a deep layer. The deep layer is located under the base region, extends to a depth deeper than the trench and is formed along an approximately normal direction to a sidewall of the trench.
US08193557B2 Sub-assembly for a light-emitting device package and a light emitting diode package with features preventing encapsulant delamination
A sub-assembly of a light-emitting device package and/or a light-emitting device package, the package comprising a cavity filled with an encapsulant, are disclosed with means preventing the encapsulant delamination. The means comprise an expansion volume within the light-emitting device package, together with means allowing the encapsulant to flow from the cavity into the expansion volume as the encapsulant expands, and to flow back into the cavity as the encapsulant contracts during heating and cooling of the light-emitting device package.
US08193554B2 Optical member having photocurable resin and method for manufacturing the optical member
There is provided an optical member 1 in which a fixation member 3 supporting the light emitting member 2 is fixed to a housing 5 supporting a light receiving member 4, so as to have clearances between the fixation member 3 and the housing 5, by photocurable resin 6 bridging the clearances, recesses 7 that adjoin positions where the photocurable resin 6 is deposited, that are opened so as to allow casting of light into the recesses 7, and that are to receive portions of the photocurable resin 6 are formed on the housing 5.
US08193548B2 Light-emitting diode
An light emitting diode includes an n-type nitride semiconductor layer, a multiple quantum well layer, a p-type nitride semiconductor layer, a window electrode layer, a p-side electrode, and an n-side electrode, which are stacked in this order. The n-side electrode is electrically connected to the n-type nitride semiconductor layer. The window electrode layer comprises an n-type single-crystalline ITO transparent film and an n-type single-crystalline ZnO transparent film. The p-type nitride semiconductor layer is in contact with the n-type single-crystalline ITO transparent film. The light-emitting diode further comprises a plurality of single-crystalline ZnO rods formed on the n-type single-crystalline ZnO transparent film. The respective lower portions of the single-crystalline ZnO rods have a shape of an inverted taper, which sharpens from the single-crystalline n-type ZnO transparent film toward the n-type nitride semiconductor layer.
US08193546B2 Light-emitting-diode array with polymer between light emitting devices
A light-emitting-diode (LED) array includes a first LED device having a first electrode and a second LED device having a second electrode. The first and the second LED device are formed on a common substrate and are separated by a gap. At least one polymer material substantially fills the gap. An interconnect, formed on top of the at least one polymer material, electrically connects the first electrode and the second electrode.
US08193543B2 Monochromatic light source with high aspect ratio
Light emitting systems are disclosed. The light emitting system includes an LED that emits light at a first wave-length. A primary portion of the emitted first wavelength light exits the LED from a top surface of the LED that has a minimum lateral dimension Wmin. The remaining portion of the emitted first wavelength light exits the LED from one or more sides of the LED that has a maximum edge thickness Tmax (122, 124). The ratio Wmin/Tmax is at least 30. The light emitting system further includes a re-emitting semiconductor construction that includes a semiconductor potential well. The re-emitting semiconductor construction receives the first wavelength light that exits the LED from the top surface and converts at least a portion of the received light to light of a second wavelength. The integrated emission intensity of all light at the second wavelength that exit the light emitting system is at least 4 times the integrated emission intensity of all light at the first wavelength that exit the light emitting system.
US08193541B2 Light emitting diode structure having a conductive thin film for connecting a light emitting stack to an electrode and LED packaging structure using the same
A light emitting diode (LED) structure and a LED packaging structure are disclosed. The LED structure includes a sub-mount, a stacked structure, an electrode, an isolation layer and a conductive thin film layer. The sub-mount has a first surface and a second surface opposite the first surface. The stacked structure has a first semiconductor layer, an active layer and a second semiconductor layer that are laminated on the first surface. The electrode is disposed apart from the stacked structure on the first surface. The isolation layer is disposed on the first surface to surround the stacked structure as well as cover the lateral sides of the active layer. The conductive thin film layer connects the electrode to the stacked structure and covers the stacked structure.
US08193537B2 Optically controlled silicon carbide and related wide-bandgap transistors and thyristors
An optically active material is used to create power devices and circuits having significant performance advantages over conventional methods for affecting optical control of power electronics devices and circuits. A silicon-carbide optically active material is formed by compensating shallow donors with the boron related D-center. The resulting material can be n-type or p-type but it is distinguished from other materials by the ability to induce persistent photoconductivity in it when illuminated by electromagnetic radiation with a photon energy in excess of the threshold energy required to photoexcite electrons from the D-center to allowed states close to the conduction band edge, which varies from polytype to polytype.
US08193535B2 Thin film transistor, including compound semiconductor oxide, method of manufacturing the same and flat panel display device having the same
A thin film transistor, a method of manufacturing the thin film transistor, and a flat panel display device including the thin film transistor. The thin film transistor includes: a gate electrode formed on a substrate; a gate insulating film formed on the gate electrode; an activation layer formed on the gate insulating film; a passivation layer including a compound semiconductor oxide, formed on the activation layer; and source and drain electrodes that contact the activation layer.
US08193532B2 Thin film integrated circuit device, IC label, container comprising the thin film integrated circuit, manufacturing method of the thin film integrated circuit device, manufacturing method of the container, and management method of product having the container
The present invention provides an ultrathin thin film integrated circuit and a thin film integrated circuit device including the thin film integrated circuit device. Accordingly, the design of a product is not spoilt while an integrated circuit formed from a silicon wafer, which is thick and produces irregularities on the surface of the product container. The thin film integrated circuit according to the present invention includes a semiconductor film as an active region (for example a channel region in a thin film transistor), unlike an integrated circuit formed from a conventional silicon wafer. The thin film integrated circuit according to the present invention is thin enough that the design is not spoilt even when a product such as a card or a container is equipped with the thin film integrated circuit.
US08193528B2 Azapyrenes for electronic applications
The present invention relates to electronic devices, especially electroluminescent devices, comprising azapyrenes of formula (I), or formula (III), wherein Y1, Y2, Y3, Y4, X1, X2 and X3 are independently each other N, or CR4, with the proviso that at least one of the groups X1, X2 and X3 is a group CR4, R1 is hydrogen, F, —SiR100R101R102, or an organic substituent, R4 is hydrogen, F, —SiR100R101R102, or an organic substituent, or any of the substituents R1, R1′ and R4, which are adjacent to each other, together form an aromatic, or heteroaromatic ring, or ring system, which can optionally be substituted, m is an integer of 1 to 6, and R100, R101 and R102 are independently of each other a C1-C8alkyl group, a C6-C24aryl group, or a C7-C12aralkyl group, which may optionally be substituted, and Q is a linking group; with the proviso that in the compound of formula (III) at least one of the substituents R1, or R4 is a group Q; especially as host for phosphorescent emitters, electron transporting materials, or emitter materials. The hosts may function with phosphorescent materials to provide improved efficiency, stability, manufacturability, or spectral characteristics of electroluminescent devices.
US08193526B2 Transistor having an organic semiconductor with a hollow space
A semiconductor device having a semiconductor elements formed with higher density is provided. Furthermore an image display device using the semiconductor device is also provided.A semiconductor device comprising a resin film that has a through hole that penetrates from one surface to the other surface thereof, a source electrode disposed along the inner wall of the through hole, a drain electrode disposed along the inner wall of the through hole, a gate electrode disposed on the other surface of the resin film opposing the through hole, an insulating layer disposed on the gate electrode at the bottom of the through hole and an organic semiconductor disposed in the through hole so as to contact the source electrode and the drain electrode, wherein the organic semiconductor makes contact with at least a part of the insulating layer at the bottom of the through hole so that a channel is formed in the organic semiconductor in the vicinity of the insulating layer that is in contact therewith.
US08193520B2 Particle beam therapy system
There is provided a particle beam therapy system that can rapidly change beam energy without increasing the size of a deflection electromagnet even in the case where the number of required beam-energy changes is large.There is provided a plurality of beam energy changing units each provided with a beam energy attenuation unit; a beam is deflected in such a way as to sequentially passes through the plurality of beam energy changing units; while a beam passes through one of the beam energy changing unit, the beam energy attenuation amount of another beam energy changing unit is changed.
US08193519B2 Illuminating waveguide fabrication method
A nanolithography system comprising a novel optical printing head suitable for high throughput nanolithography. This optical head enables a super-resolution lithographic exposure tool that is otherwise compatible with the optical lithographic process infrastructure. The exposing light is transmitted through specially designed super-resolution apertures, of which the “C-aperture” is one example, that create small but bright images in the near-field transmission pattern. A printing head comprising an array of these apertures is held in close proximity to the wafer to be exposed. In one embodiment, an illumination source is divided into parallel channels that illuminate each of the apertures. Each of these channels can be individually modulated to provide the appropriate exposure for the particular location on the wafer corresponding to the current position of the aperture. A data processing system is provided to re-interpret the layout data into a modulation pattern used to drive the individual channels. In one embodiment of the invention, the exposure head remains stationary while the material to be exposed rotates beneath the head. Such an embodiment comprises a circular data fracturing system to process the layout data to determine the correct modulation pattern.
US08193518B2 Device and method for spatial reconstructing of fluorescence mapping
The invention concerns a method for locating at least one fluorophore or at least one absorber in a diffusing medium, using at least one excitation radiation and at least one fluorescence detector (Φfluo), comprising:a) for at least one pair (radiation source-detector), at least one excitation by the radiation source, and at least one detection of the fluorescence signal emitted by the fluorophore after this excitation,b) identification of meshing of the volume into mesh elements,c) estimation of the location of the fluorophore or absorber in its diffusing medium, by computing a function (Pm) of at least one of three parameters.
US08193510B2 Radiation detector
The present invention provides a radiation detector with improved workability in manufacturing processes and maintenance processes. Namely, a first housing and a second housing can be opened, to allow accessing of a TFT substrate and a radiation converting layer disposed in the first housing, and to allow accessing of a circuit substrate disposed in the second housing. Accordingly, higher workability can be achieved in manufacturing processes such as connecting of switching elements of the TFT substrate and the circuit substrate, and in maintenance processes of the TFT substrate and the circuit substrate.
US08193508B2 Detecting photons in the presence of a pulsed radiation beam
A detector system adapted for monitoring a radiation treatment system comprising a pulsed beam radiation source for treating a body with a given beam intensity and beam configuration, with pulse times and intervals between pulses less than 100 milliseconds, using at least one monitoring radiation source located inside or outside the body, the detector system comprising; a) a detector designed to detect radiation from the monitoring source, and subject to interference radiation from the beam source; and b) control circuitry that creates a data record of radiation received by the detector, to provide information about the body; wherein, when the detector detects radiation in real time during operation of the beam, the data record selectively excludes data for radiation received by the detector during the pulses, as opposed to data for radiation received by the detector between pulses.
US08193505B2 System and method for scatter normalization of PET images
In positron emission tomography (PET), a detector's response to scattered radiation may be different from its response to unscattered (true coincidence) photons. This difference should be accounted for during normalization and scatter correction. The disclosure shows that only a knowledge of the ratio of the scatter to trues efficiencies is necessary, however. A system and method are disclosed for measuring the scatter/trues detection efficiency ratio, as well as for applying this compensation during the scatter correction of PET emission data. PET detector efficiencies are measured in two steps, the first using a plane radiation source, and the second using a plane radiation source in combination with a scattering medium. A ratio of the scatter and trues detection efficiency is obtained from this data for each detector/crystal, and is applied as a correction factor to PET data obtained during medical imaging processes.
US08193502B2 Optical absorption gas sensor
An optical absorption gas sensor comprising a body having an internal wall which defines a chamber, at least one aperture in the body through which a gas sample can enter the chamber, a light source, at least one reflector, a detector assembly which extends into the chamber and has a first side and an opposite second side, a detector which measures light which is incident at least a range of angles on at least a part of a first surface of the detector assembly on the first side of the detector assembly, wherein the light source is located within the chamber on the second side of the detector assembly, the whole being configured such that light from the light source passes through the gas sample and is reflected around the detector assembly, by the at least one reflector, onto the detector.
US08193500B2 Discrimination filtering device, discrimination method of object, and designing method of filters for discrimination filtering device
A discrimination filtering device includes a filter and a filter having different pass bands, a detection unit, a processing unit, and a result output unit. The detection unit detects an electromagnetic wave from an object that is the target of identification through the filters. The pass band of the filters is designed to be suitable for object discrimination. The processing unit substitutes the output from the detection unit into a discrimination function determined based on the pass band of the filters and the teaching spectrum obtained in advance to infer the group which the object belongs to based on the substituted result.
US08193499B2 Surface enhanced infrared absorption sensor and method for producing the same
The method for producing a surface enhanced infrared absorption sensor of the invention is characterized by: adsorbing metallic nanoparticles dispersed in a solution on a surface of a substrate, or allowing the adsorbed metallic nanoparticles to be grown in a solution, thereby forming a film; applying infrared light to the substrate from the side thereof opposite to the side on which the metallic nano-thin film is disposed; detecting evanescent waves exuding from the substrate; and regulating a surface enhanced infrared adsorption activity while monitoring surface enhanced infrared adsorption signals in situ, whereby the metallic nano-thin film is grown in the form of flat and discontinuous islands. According to the method, there is provided a production technique for a surface enhanced infrared absorption (SEIRA) sensor having a higher sensitivity and more excellent in the reproducibility.
US08193497B2 Near-infrared photodetectors, image sensors employing the same, and methods of manufacturing the same
Silicon photodetectors using near-infrared dipole antennas. The photodetectors include a silicon region formed on a semiconductor substrate, dipole antenna forming two arms that are spaced apart with the silicon region therebetween and inducing an electromagnetic wave signal of incident light, and electrodes disposed in a vertical direction of the dipole antenna and spaced apart with the silicon region therebetween, where a critical bias voltage is applied to the electrodes to induce an avalanche gain operation in the silicon region.
US08193495B2 Tool for dicorotron wire assembly removal and storage
A system and apparatus that removes and collects non-functional wire assemblies from dicorotron units is described. It has a removal tool with flexible levers mounted on the top of a storage box. The removal tool has an open top and bottom, the open bottom is aligned with an opening in the top of the box to permit a dislodged anchor and wire assembly to fall therethrough.
US08193494B2 Transmission electron microscope and method for observing specimen image with the same
A first electron biprism is disposed in a condenser optical system and an observation region of a specimen is irradiated simultaneously with two electron beams of different angles. The two electron beams that have simultaneously transmitted the specimen are spatially separated and focused with a second electron biprism disposed in an imaging optical system and two electron microscopic images of different irradiation angles are obtained. The two picture images are obtained by a detecting unit. Based on the two picture images, a stereoscopic image or two images having different kinds of information of the specimen is/are produced and displayed on a display device.
US08193493B2 Charged particle beam apparatus
A charged particle beam apparatus that can achieve both high defect-detection sensitivity and high inspection speed for a sample with various properties in a multi-beam type semiconductor inspection apparatus. The allocation of the primary beam on the sample is made changeable, and furthermore, the beam allocation for performing the inspection at the optimum inspection specifications and at high speed is selected based on the property of the sample. In addition, many optical parameters and apparatus parameters are optimized. Furthermore, the properties of the selected primary beam are measured and adjusted.
US08193491B2 Structure and method for determining a defect in integrated circuit manufacturing process
The present invention discloses a structure and a method for determining a defect in integrated circuit manufacturing process. Test keys are designed for the structure to be the interlaced arrays of grounded and floating conductive cylinders, and the microscopic image can be predicted to be an interlaced pattern of bright voltage contrast (BVC) and dark voltage contrast (DVC) signals for a charged particle beam imaging system. The system can detect the defects by comparing patterns of the detected VC signals and the predicted VC signals.
US08193486B2 Security inspection system for persons
The invention provides a security inspection system for inspecting persons, characterized in that it comprises: a passageway which provides an inspection space isolated or partially isolated from an ambient environment, in which at least one sub-passageway allowing persons to be inspected to pass is provided in the inspection space, and each of the sub-passageways is provided with at least one millimeter wave imaging device for millimeter wave imaging of persons being inspected; and an ion mobility spectrometer for ionizing particles of substance or gases that are released or volatilized from the inspected persons into the air in the passageway and then measuring a mobility rate thereof under the action of the electric field to effect identification of substances. At least one radioactive substance inspection device may also be provided in the passageway to detect whether the person being inspected carries radioactive substances.
US08193485B2 Method and apparatus for identifying proteins in mixtures
Protein identification in a complex sample begins by selecting a database having proteins likely to be in the sample. In-silico digestion is performed and a target peptide is selected from produced peptides. The masses of the Y- and B-ion fragments of the target peptide are determined. These masses are used to search previously obtained low- and high-energy AMRTs obtained from LC/MS analysis of the complex sample for masses on the list. Any mass observed in the data within a detection threshold are considered a hit. If enough hits accumulate in a given retention time, the target peptide is identified as being in the sample. The list of peptides identified in the complex sample can be used to identify the proteins present in the sample, track the chromatographic retention times of peptides between samples, and quantitate the peptides and proteins present in complex samples.
US08193483B2 Optical encoder systems, devices and methods
Disclosed are various embodiments of high-speed, high-performance, low-noise optical encoders having various means for preventing undesired stray light from reaching light detectors incorporated therein. Structures employed to block stray light in the optical encoders include light barriers, air gap trenches, and coatings disposed between first and second sides of a substrate of the encoder. Also disclosed are compact single track optical encoders having a single dome lens disposed thereover, and dual track triple dome lens optical encoders. Methods of making such optical encoders are also disclosed.
US08193481B2 Method and apparatus for assembling sensor output data with data representing a sensed location on a moving article
A method for assembling output data generated by at least one sensor unit having a local clock and linked to a data communication network with corresponding data representing sensed location on an article moving at a known speed or position/time profile along a travel path intersecting a sensing field associated with the sensor unit, makes use of reference time data that is compared with local time data generated by the local clock when the reference time data is received, causing a local clock update. Then, the sensor output data is assembled with the corresponding sensed location data according to an associated updated time data.
US08193480B2 Projection system having a virtual mask
A projection system includes a projection screen defining a shape and a projector configured to project an image onto the projection screen. The projector may project a static or dynamic image that has substantially the same shape as the projection screen or otherwise block portions of the projected image that are projected outside of the projection screen with the aid of a virtual mask. The virtual mask and the projection screen may be created based on a virtual shape template that defines the desired shape for the projection screen, such as with a vector outline. In some embodiments, the virtual mask and the projection screen are created based on the same virtual shape template. The virtual shape template may define a cutting path for extracting the projection screen from a suitable material.
US08193479B2 Very small image sensor
An image sensor formed in a semiconductor stack of a lower region of a first conductivity type and of an upper region of a second conductivity type, including: a photodiode formed of a first portion of the stack; a read area formed of a second portion of the stack; a trench with insulated walls filled with a conductive material, the trench surrounding the photodiode and the read area and being interrupted, all along its height, on a portion facing the photodiode and the read area; and first connection mechanism associated with the conductive material of the trench and capable of being connected to a reference bias voltage.
US08193476B2 Solid-fuel pellet thrust and control actuation system to maneuver a flight vehicle
A solid-fuel pellet thrust and control actuation system (PT-CAS) provides command authority for maneuvering flight vehicles over subsonic and supersonic speeds and within the atmosphere and exo-atmosphere. The PT-CAS includes a chamber or solid-fuel pellets that are ignited to expel gas through a throat. The expelled gas is directed at supersonic vehicle speeds in atmosphere to a cavity between an aero control surface and the airframe to pressurize the cavity and deploy the surface or at subsonic speeds in atmosphere or any speed in exo-atmosphere allowed to flow out a through-hole in the surface where the throat and through-hole provide a virtual converging/diverging nozzle to produce a supersonic divert thrust. A pellet and control actuation system (P-CAS) without the through-hole provides command authority at supersonic speeds in atmosphere. A restrictor mechanism controls the bleed of pressurized gas from the cavity to the external environment to achieve a deployment time objective for either the PT-CAS or P-CAS.
US08193474B2 Smart sensing oven
Smart oven allows contactless detection of surface temperature of an item being heated. The temperature of the heated object can be maintained at the specified temperature for a specified time. The program for cooking can be read automatically from a package from the food, e.g, from a bar code on the package. When the preheating or cooking is finished, a text message can be sent to a user.
US08193472B2 Susceptor
A susceptor [1] is manufactured by providing a protruding part [8] on the joining surface of a retainer plate [4], and additionally providing a groove part [9] composed of a dovetail groove on the joining surface of a heat transfer plate [3] in a position facing the protruding part [8]. By fitting the protruding part [8] into the groove part [9] and caulking, the heat transfer plate [3] and the retainer plate [4] are conjoined.
US08193471B2 Breadmaker with a hidden heating element
The present invention relates to a breadmaker, in which the heating element is shieldingly protected in the shell body without being exposed outside so as to prevent people's hand from touching and being hurt by the heating element, more important, it is able to avoid getting flour falling onto the heating element and being baked excessively to stick on the heating element which may lead to a fire, thus the breadmaker of the present invention is more safely to operate and conforms to the requirements of European safety standards. The breadmaker comprises a shielding member for the heating element, and the shielding member is disposed between the heating element and the upper opening of the bread vessel, the downward projection of the shielding member can completely cover the contour of the heating element so as to completely shield the heating element from the above.
US08193469B2 Ceramic igniters
Ceramic igniters are provided that comprise at least three zones of differing electrical resistance, preferably in sequence a first conductive zone of relatively low resistance, a power booster or enhancement zone of intermediate resistance, and a further hot or ignition zone of high resistance. Igniters of the invention can provide extremely high speeds (low time-to-temperature).
US08193466B2 Capacitive input device with removable cover
An information handling system can include a base, a printed circuit board including a capacitive switch, and a cover. The printed circuit board can be attached to the base, and the cover can lie adjacent to the printed circuit board. The capacitive switch can be configured to change state when an object is close to the cover. The cover can be configured such that it can be detached from the remainder of the information handling system while the printed circuit board remains attached to the base. The configuration of the printed circuit board and cover can be particularly useful when maintaining a keyboard or a touch pad or when replacing the cover.
US08193464B2 Micro switch
Disclosed is a micro switch having a high capability of cutting off a direct current. In the micro switch including a stationary contact, a movable contact having a closed position where it contacts the stationary contact or an open position where it is separated from the stationary contact, a movable contact rod for supporting the movable contact, a plunger for pressurizing the movable contact rod upon being pressed, and a leaf spring for supplying a driving force to the movable contact rod to convert a position of the contacts being contacted or separated, a permanent magnet is installed at a position adjacent to the movable contact and the stationary contact, so as to extend an arc generated between the movable contact and the stationary contact upon separating the movable contact from the stationary contact, whereby the arc can be fast extinguished.
US08193461B2 Electrical switch, particularly of microswitch design
The invention relates to an electrical switch (10), particularly of microswitch design, comprising at least one pair of switching contacts (42, 60), which can be moved, relative to one another, between an in-contact position and an out-of-contact position, for the purpose of making and breaking an electrical path leading via the two switching contacts (42, 60), and comprising spring means (40), which bias at least one of the two switching contacts in the direction of one of the two relative positions, the spring means (40) comprising, according to a preferred design, a helical spring (40), which is made of an electrically conductive material, is loaded substantially in the direction of its spring axis, and is located in the electrical path in series with the switching contact pair (42, 60).
US08193460B2 Steering wheel horn switch
A horn switch (40) for a vehicle steering wheel (20) includes a frame (50) for mounting to the steering wheel (20). The frame (50) includes a horn switch housing (56). A plunger (80) is associated with the switch housing (56). The plunger (80) is movable relative to the switch housing (56) between a non-actuating position and an actuating position. An actuatable cable (150) has a portion positioned in the switch housing (56). The actuating cable (150) includes first and second conductors (156, 158) for electrical connection to a circuit that when closed actuates a vehicle horn (30). The actuatable cable (150) has an expanded condition in which the first and second conductors (156, 158) are insulated from each other when the plunger (80) is in the non-actuating position. The plunger (80) when in the actuating position acting on the cable (150) to place the cable (150) in a compressed condition in which electrical continuity is established between the first and second conductors (156, 158) to close the circuit and actuate the vehicle horn (30).
US08193459B2 Lug-jaw for electrical joint
A disconnect assembly for making and breaking electrical connections to an electrical circuit. The disconnect assembly includes a pullout assembly and a base assembly. The pullout assembly has downwardly facing extensions with slits in them to receive a blade that is inserted securely through the slits. The exposed portions of the blade are received in corresponding lug-jaw connectors in the base assembly. The lug-jaw connectors have a lug and a half jaw attached to the lug. The half jaw has a curved clip portion that opposes a side surface of the lug such that the exposed portion of the blade is received between the clip portion and the side surface, thereby resulting in minimal use of conductive material for the disconnect assembly.
US08193458B2 Electric tool switch
An electric tool switch has an operation member turnable in both directions and biased to self-return to a neutral position, a circuit substrate arranged to be orthogonal to a turning shaft of the operation member, a slidably moving element which is pressed against the circuit substrate and which is turned with the operation member to slidably contact the circuit substrate, and an inversion mechanism for switching a polarity between output terminals according to the turning direction of the operation member from the neutral position. The circuit substrate is formed with two sets of variable resistor circuits, which close a circuit when the slidably moving element slidably contacts and which resistance value changes according to a contacting position of the slidably moving element, electrically connected in parallel on both sides in the turning direction from a position corresponding to the neutral position of the operation member.
US08193456B2 Electrical inspection substrate unit and manufacturing method therefore
An electrical testing substrate unit includes a multi-layer ceramic substrate formed of mullite and a borosilicate glass as predominant ceramic components. In the multi-layer ceramic substrate, the borosilicate glass contains an alkali metal oxide in an amount of 0.5 to 1.5 mass %. The multi-layer ceramic substrate has a mean coefficient of linear thermal expansion having a value of 3.0 to 4.0 ppm/° C. between −50° C. and 150° C. A thermal expansion coefficient, α1, of the multi-layer ceramic substrate as determined at a particular temperature and a thermal expansion coefficient, α2, of a to-be-tested silicon wafer as determined at the same temperature silicon satisfy a relation: 0 ppm/° C.<α1−α2≦2.5 ppm/° C. through the temperature range of −50° C. to 150° C. Electrodes are formed on a surface of the multi-layer ceramic substrate.
US08193453B2 Electronic apparatus and printed wiring board
According to an aspect of the present invention, there is provided a printed wiring board including: a substrate including a pair of edges and a fixing hole adjacent to the pair of edges and configured to receive a bolt; a land provided in a vicinity of the fixing hole and extending in a direction from the fixing hole toward a center of the substrate and along the pair of edges; and an insulating height adjuster provided between the fixing hole and the pair of edges and configured to have substantially the same height as the land.
US08193446B1 Wall mount electrical box
An electrical box mountable within a wall and installable from outside the wall. The box has a pan that includes a front flange for contacting an outer wall surface that extends outwardly from a sidewall. A back bracket is positioned opposite the front flange and adjacent to the back wall and a fastener having a shaft extends through the back wall to movably secure the back bracket to the back wall. No portion of the shaft extends behind the back bracket. The back bracket is movable relative to the pan between a first position adjacent to the back wall and a second position spaced farther from the back wall. The bracket and front flange are adapted for clamping a portion of a wall located between the front flange and back bracket when the back bracket is in its first position.
US08193440B1 Hybrid electric generator
A device for producing energy and power utilizing incoming solar radiation to invoke a thermal differential inside the device to produce an electric current utilizing a phenomenon more commonly known as the Seebeck effect, which produces energy by heating the junction between two dissimilar metals to create an electric current stemming from both their other ends.
US08193427B1 Maize variety hybrid X7R417
A novel maize variety designated X7R417 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety X7R417 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X7R417 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X7R417, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X7R417. This invention further relates to methods for producing maize varieties derived from maize variety X7R417.
US08193424B2 Soybean variety A1016522
The invention relates to the soybean variety designated A1016522. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1016522. Also provided by the invention are tissue cultures of the soybean variety A1016522 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1016522 with itself or another soybean variety and plants produced by such methods.
US08193421B2 Soybean cultivar S080117
A soybean cultivar designated S080117 is disclosed. The invention relates to the seeds of soybean cultivar S080117, to the plants of soybean S080117, to plant parts of soybean cultivar S080117, and to methods for producing a soybean plant produced by crossing soybean cultivar S080117 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080117, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080117, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080117 with another soybean cultivar.
US08193418B1 Soybean variety XB48G09
According to the invention, there is provided a novel soybean variety designated XB48G09. This invention thus relates to the seeds of soybean variety XB48G09, to the plants of soybean XB48G09 to plant parts of soybean variety XB48G09 and to methods for producing a soybean plant produced by crossing plants of the soybean variety XB48G09 with another soybean plant, using XB48G09 as either the male or the female parent.
US08193415B2 Plant expressing mammalian β1,4-galactosyltransferase and β1,3-glucuronyltransferase
The invention relates to the field of glycoprotein processing in transgenic plants used as cost efficient and contamination safe factories for the production of recombinant biopharmaceutical proteins or pharmaceutical compositions comprising these. The invention provides a plant comprising a functional mammalian enzyme providing N-glycan biosynthesis that is normally not present in plants, said plant additionally comprising at least a second mammalian protein or functional fragment thereof that is normally not present in plants.
US08193410B2 Transgenic plants with controlled distribution of a trait to progeny
A process of producing a transgenic multi-cellular plants or parts thereof expressing a trait of interest, said trait having a controlled distribution of said trait to progeny, wherein said process comprises (i) producing a first plant or a cell thereof having in a first locus of a nuclear chromosome a first heterologous nucleotide sequence comprising a first fragment of a nucleotide sequence encoding said trait of interest, (ii) producing a second plant or a cell thereof having in a second locus of a nuclear chromosome homologous to said nuclear chromosome of step (i), a second heterologous nucleotide sequence comprising a second fragment of the nucleotide sequence encoding said trait of interest, and (iii) hybridising said first and said second plant or cells thereof to generate progeny exhibiting said functional trait of interest due to binding between a protein or polypeptide encoded by said first heterologous nucleotide sequence and a protein or polypeptide encoded by said second heterologous nucleotide sequence. Further, the invention provides a process of producing hybrid seeds for agriculture.
US08193409B2 Nucleotide sequences and polypeptides encoded thereby useful for increasing plant size and increasing the number and size of leaves
Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants that are characterized by increased size, have an increased number and size of rosette leaves and are late-flowering.
US08193406B2 Super-hydrophobic bandages and method of making the same
A bandage that includes a material, which can be breathable, having a first surface, and a plurality of superhydrophobic particles attached to the first surface. The plurality of superhydrophobic particles ranging in size from about 100 nanometers to about 10 micrometers. The superhydrophobic particles including a protrusive material defining a plurality of nanopores and a plurality of spaced apart nanostructures that define an external boundary of the hydrophobic particles. The nanopores providing a flow through porosity. The first surface can be rendered superhydrophobic by the attached superhydrophobic particles. The material can have a second surface opposite the first surface that is hydrophilic. The superhydrophobic particles can be adhered to the first surface by a binder. Also included is a method of making the bandages described herein.
US08193400B2 Production of diesel fuel from renewable feedstocks
A process has been developed for producing diesel fuel from renewable feedstocks such as plant oils and greases. The process involves treating a renewable feedstock by hydrogenating and deoxygenating i.e. decarboxylating and/or hydrodeoxygenating to provide a hydrocarbon fraction useful as a diesel fuel. If desired, the hydrocarbon fraction can be isomerized to improve cold flow properties. A portion of the hydrogenated and deoxygenated feedstock is selectively separated and then recycled to the treatment zone to increase the hydrogen solubility of the reaction mixture. A diesel range stream or a naphtha range stream, or a mixture of the two streams is used as a rectification agent in the selective hot high pressure hydrogen stripper to decrease the amount of product carried in the overhead.
US08193398B2 Processes for production and purification of normal propyl bromide
A process for oxygen-initiated hydrobromination of propene to form a crude reaction mixture of 95 GC area % n-propyl bromide. The process includes feeding an oxygen-containing gas, propene and hydrogen bromide into a liquid phase mixture comprised of n-propyl bromide and hydrogen bromide. At least the oxygen-containing gas and the propene of the feed are fed subsurface to the liquid phase mixture and either (a) the oxygen-containing gas and the propene do not come together in the absence of hydrogen bromide or (b) the oxygen-containing gas and the propene come together only in a propene:oxygen molar ratio in the range of 145:1 to 180:1. Purification processes provide a propyl bromide product containing at least 99.7 GC area % n-propyl bromide. Also provided is a novel composition of enhanced thermal stability which comprises a mixture of n-propyl bromide and isopropyl bromide. The mixture has an n-propyl bromide content of at least 99.7 GC area %, and an isopropyl bromide content of no more than 0.05 GC area %. The mixture, if subjected to storage in a closed chemically inert container at 60° C. for at least 480 hours, has an APHA color of 10 or less while the mixture is devoid of any added stabilizer component.
US08193396B2 Process for producing allyl alcohol
A process for producing allyl alcohol is disclosed. The process comprises reacting propylene, acetic acid, and oxygen to produce a reaction mixture. The reaction mixture is distilled to produce a vapor stream comprising propylene and a liquid stream comprising allyl acetate, acetic acid, acrolein, and allyl diacetate. The liquid stream is distilled to produce a lights stream comprising acrolein; a side draw comprising allyl acetate, acetic acid, and water; and a bottoms stream comprising acetic acid and allyl diacetate. The bottoms stream is distilled to remove a heavies stream comprising allyl diacetate. The side draw is hydrolyzed to produce allyl alcohol.
US08193392B2 Method for enantioselective synthesis of phosphorus-stereogenic phosphines
The present invention relates to a process for preparing an enantioenriched phosphorus-stereogenic, tertiary phosphine. Secondary phosphines are contacted with an alkyl halide and base in the presence of a chiral metal catalyst thereby producing the enantioenriched phosphorus-stereogenic, tertiary phosphine for subsequent use in homogeneous catalysis reactions.
US08193389B2 N-substituted benzene sulfonamides
The invention provides N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula (I), wherein R1, R2, R3, R4, and R3′, are as described in the specification. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating cognitive disorders, including Alzheimer's disease using compounds of Formula (I).
US08193386B2 Crystalline form of (S)-1-phenylethylammonium (R)-diphenylmethanesulphinyl-acetate
Novel crystalline hydrate form of (S)-1-phenylethylammonium (R)-diphenyl-methanesulphinyl-acetate and its use in a process for the preparation of (R)-benzhydrylsulphinylacetamide.
US08193384B2 Polymer-bound phosphitylating reagents for the synthesis of organophosphorus compounds
The synthesis and biochemical utility of modified oligonucleotides containing diphosphodiester internucleotide linkages. The synthesis of these compounds was carried out using diphosphitylating reagents. Oligonucleotides containing diphosphate diester bridges wherein said oligonucleotides are synthesized via a solid-phase synthesis strategy to form modified oligonucleotides. Diphosphitylating, triphosphitylating, tetraphosphitylating, β-triphosphitylating, bifunctional diphosphitylating, bifunctional triphosphitylating, and bifunctional tetraphosphitylating reagents wherein, the phosphorus atoms are linked together through oxygen, sulfur, amino, or methylene groups and/or are substituted with chlorine, diisopropylamine and cyanoethoxy groups.
US08193383B2 Process for continuously preparing fatty acid methyl esters or fatty esters
In a process for producing fatty acid methyl ester (FAME) from fats or oils by transesterification with methanol in the presence of an alkaline catalyst in at least two reaction stages traversed in succession, each consisting of a stirred-tank reactor and a downstream separator, a phase containing FAME and a phase containing glycerol are generated, which are separated in the separator, wherein the phase containing FAME is recirculated into the stirred-tank reactor of the next succeeding reaction stage and the phase containing glycerol is recirculated into the stirred-tank reactor of the first reaction stage, and the crude FAME withdrawn from the separator of the last reaction stage is transferred into a separator and the FAME withdrawn is dried. To increase the yield of FAME, the aqueous phase containing glycerol, methanol, undissociated soaps and FAME, which is obtained upon withdrawal of the FAME, is thoroughly mixed with the phases withdrawn from the separators of the first to penultimate reaction stages, which contain glycerol and FAME, and the mixture is separated in a separator into a phase containing FAME and a phase containing glycerol.
US08193379B2 Method for preparing 4B-amino-4′-demethyl-4-desoxypodophyllotoxin
The invention relates to a method for synthesizing 4β-amino-4′-demethyl-4-desoxypodophyllotoxin of formula (1), characterized by comprising the following successive steps: a) reacting, in a pure weak acid or in a mixture consisting of acid, water and of organic solvent, without another solvent, at a temperature higher than the ambient temperature, thiourea with 4β-halogenoacetamido-4′-demethyl-4-desoxypodophyllotoxin, and; b) recovering the 4β-amino-4′-demethyl-4-desoxypodophyllotoxin.
US08193377B2 (−)-epigallocatechin gallate derivatives for inhibiting proteasome
(−)-EGCG, the most abundant catechin, was found to be chemopreventive and anticancer agent. However, (−)-EGCG has at least one limitation: it gives poor bioavailability. This invention provides compounds of generally formulae below, wherein R11, R12, R13, R21, R22, R2, R3, and R4 are each independently selected from the group consisting of —H, and C1 to C10 acyloxyl group; and R5 is selected from the group consisting of —H, C1-C10-alkyl, C2-C10-alkenyl, C2-C10-alkynyl, C3-C7-cycloalkyl, phenyl, benzyl and C3-C7-cycloalkenyl, whereas each of the last mentioned 7 groups can be substituted with any combination of one to six halogen atoms; at least one of R11, R12, R13, R21, R22, R2, R3 and R4 is —H, which were found to be more potent than their non-protected counterparts, which can be used as proteasome inhibitors to reduce tumor cell growth.
US08193376B2 Artemisinin derivatives with natural amino acids, peptides, and amino sugars for the treatment of infection and topical condition in mammals
The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars, and isomers and salts thereof (formula I). The compounds of the present invention possess wide-spectrum antibacterial and antifungal biological activity suitable for topical or oral application for the treatment of infections and topical ailments in mammals, including acne, rosacea, topical wounds, infections, dandruff, skin disfigurements caused by infection, skin discoloration, age spots, wrinkles, excess facial oil, and veterinary problems including canine infections;
US08193374B2 Process for the preparation of alkylene carbonate and/or alkylene glycol
The invention provides a reaction system for the production of an alkylene carbonate and/or an alkylene glycol comprising: an epoxidation zone containing an epoxidation catalyst located within an epoxidation reactor; a carboxylation zone containing an iodide-containing carboxylation catalyst located within an alkylene oxide absorber; and one or more purification zones containing a purification absorbent capable of reducing the quantity of iodide-containing impurities in a feed comprising a recycle gas, which purification zones are located upstream from the epoxidation zone; and a process for the production of an alkylene carbonate and/or an alkylene glycol.
US08193370B2 Alanine racemase chiral binaphthol derivative with powerful hydrogen bond donor, and optical resolution and optical transformation methods using the same
Disclosed is an alanine racemase chiral binaphthol derivative having the ability to recognize amino alcohols selectively on the basis of chirality and transform amino acids from an L-form into a D-form. Methods for the optical resolution of amino acid or amino alcohol and for the optical transformation of D- and L-forms of amino acids using the binaphthol derivative are also provided.
US08193368B2 Tetrazole-substituted arylamides as P2X3 and P2X2/3 antagonists
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted tetrazolyl, R2 is optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R3, R4, R5 and R6 are as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.
US08193367B2 Polymorph of a pharmaceutical
A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.
US08193365B2 CETP inhibitors
Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1 and A2 are each an aromatic ring, a 5-6-membered heterocyclic ring, an aromatic ring fused to a heterocyclic ring, a phenyl ring fused to a heterocyclic ring, or a cycloalkyl ring.
US08193364B2 Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines
N-Substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines are effective at controlling insects.
US08193362B2 Insecticidal compounds
A compound of formula (I): wherein R1 is pyrid-4-yl optionally substituted by one to four substituents independently selected from halogen, C1-3 alkyl or C1-3 haloalkyl; R2 is hydrogen, halogen, C1-4 haloalkyl or C1-4 haloalkoxy; R3 is trifluoromethyl, difluoromethyl or difluoromethoxy and R4 is hydrogen, fluoro or chloro, or R3 is fluoro, chloro or bromo and R4 is fluoro, chloro or trifluoromethyl; and R5 is hydrogen or halogen; or salts or N-oxides thereof. Furthermore, the present invention relates to intermediates used to prepare compounds of formula (I), to methods of using them to combat and control insect, acarine, mollusc and nematode pests and to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them.
US08193358B2 Process for producing high-purity prasugrel and acid addition salt thereof
The present invention is directed to providing prasugrel hydrochloride or the like with a reduced content of OXTP. A method for producing prasugrel hydrochloride with a reduced content of OXTP, comprising dissolving free prasugrel containing OXTP in an inert solvent and adding hydrochloric acid optionally dropwise to the solution for reaction is also provided.
US08193356B2 Heterocycle compound, and production process and application thereof
The compound of the present invention is a novel compound which has a specific heterocycle skeleton, particularly a pyrazolonaphthyridine or pyrazoloquinoline skeleton having an organic group (e.g., a carbocycle and a heterocycle) bonding through an alkylene group at 3-position and a carbocycle bonding at 5-position and has a phosphodiesterase IV inhibitory activity. At least one of the ring (the carbocycle or the heterocycle) bonding at 3-position of the pyrazolonaphthyridine skeleton and the carbocycle bonding at 5-position may have a halogenated alkyl group and/or a halogenated alkoxy group as a substituent. Such a compound or a salt thereof is useful as a phosphodiesterase IV inhibitor and the like. According to the present invention, a novel compound having a high phosphodiesterase IV inhibitory effect can be provided.
US08193354B2 Process for preparation of Gemcitabine hydrochloride
A process for isolating β-anomer enriched Gemcitabine hydrochloride by converting Gemcitabine base into Gemcitabine hydrochloride followed by its purification using solvents from the series of water soluble ethers like 1,4-dioxane or Monoglyme.
US08193351B2 HSP90 inhibitor
Compounds represented by formula (1) shown below, pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising such compounds are provided.
US08193349B2 4-benzylamino-1-carboxylacyl-piperidine derivatives as CETP inhibitors
The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R5, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.
US08193347B2 Metal complexes of tetraazamacrocycle derivatives
Improved methods for synthesizing bifunctional chelates of tetraazamacrocycle derivatives and intermediates thereof are disclosed as well as novel tetraazamacrocycle derivatives and intermediates thereof.
US08193343B2 Manufacture and products thereof of photosensitizing nanomaterials and their use in photodynamic treatment
A method for the manufacture of a photosensitizing nanomaterial (40) and the products thereof are disclosed. The method for the treatment of a biological target (50) is disclosed. The photosensitizing nanomaterial (40) comprises a metal complex tetrapyrrole derivative (10). The metal complex tetrapyrrole derivative (10) is attached by an axial covalent bond (60) to the surface (25) of a solid nanomaterial (20). The solid nanomaterial (20) has at least one dimension in the nanometer and/or the micrometer range.
US08193338B2 Process for producing di(pyrimidine nucleoside 5'-)polyphosphate
A di(pyrimidine nucleoside 5′-)polyphosphate is synthesized by converting a pyrimidine nucleoside 5′-triphosphate into a pyrimidine nucleoside 5′-cyclic triphosphate by use of a condensing agent, and subsequently reacting the pyrimidine nucleoside 5′-cyclic triphosphate with a pyrimidine nucleotide in the presence of a salt of a metal selected from among magnesium, manganese, and iron.Through the method of the invention, a di(pyrimidine nucleoside 5′-)polyphosphate can be synthesized from an unprotected pyrimidine nucleoside 5′-phosphate serving as a starting material at a synthesis yield of 50% or higher. Therefore, the method of the invention is suitable for large-scale synthesis of a di(pyrimidine nucleoside 5′-)polyphosphate.
US08193335B2 Click chemistry for the production of reporter molecules
The present invention relates to methods for producing reporter molecules suitable for the detection of analytes, e.g. nucleic acids. Further, the present invention relates to methods and regions for detecting analytes.
US08193323B1 mpl ligand (thrombopoietin), active fragments thereof, and fusion proteins and compositions comprising mpl ligand and other cytokines
Isolated mpl ligand, isolated DNA encoding mpl ligand, and recombinant or synthetic methods of preparing mpl ligand are disclosed. These mpl ligands are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Accordingly, these compounds may be used for treatment of thrombocytopenia.
US08193322B2 Methods for generating monovalent IgG
The present invention relates to monovalent antibody, methods of making thereof and therapeutic uses thereof. In particular, the present invention provides a heterodimeric polypeptide comprising an immunoglobulin heavy chain and a fusion protein comprising an immunoglobulin light chain and an Fc molecule.
US08193321B2 Multispecific antibodies
The invention provides multispecific antibodies and methods of making and using such antibodies.
US08193319B2 Antibodies to IL-17A
Engineered antibodies to human IL-17A are provided, as well as uses thereof.
US08193313B2 Methods and compositions for tumor vaccination and therapy
The present invention relates to peptide vaccines, pharmaceutical compositions thereof, and associated methodologies that promote the immune-mediated regression of tumors expressing an onconeural antigen, e.g. a cdr-2 antigen, HuD antigen. The cancer peptide vaccines of the present invention are antigenic peptides capable of being faithfully presented on the MHC I complex of a target cell or antigen presenting cell. This external cellular presentation of these peptides promotes a specific cytotoxic T lymphocyte (CTL)-mediated immune response against tumor cells expressing these proteins, thereby, inducing immunological reactivity.
US08193312B2 Bone morphogenic protein binding peptide
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between species results in a variety of useful BBP compositions. BBP increases the over-all osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
US08193311B2 CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
An isolated polypeptide is provided. The isolated polypeptide comprising an antigen recognition domain capable of specifically binding a CD44 polypeptide as set forth in SEQ ID NO: 2 and incapable of binding a CD44 polypeptide selected from the group consisting of: SEQ ID NO: 4 or 6.
US08193309B2 Compositions and methods for preventing or treating cancer
The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer.
US08193307B2 Synthesis of photoresist polymer
A polymer for use in photoresist compositions is synthesized by effecting polymerization reaction to form a polymerization product mixture and subjecting the mixture to molecular weight fractionation by a liquid phase separation technique using a good solvent and a poor solvent. The fractionation step is iterated at least twice, and one iteration of fractionation includes adding a good solvent which is different from the good solvent added in the other iteration of fractionation.
US08193302B2 Polyester compositions which comprise cyclobutanediol and certain phosphate thermal stabilizers, and/or reaction products thereof
Described as one aspect of the invention are polyester compositions containing: (I) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) 70 to 100 mole % of terephthalic acid residues; (ii) 0 to 30 mole % of aromatic dicarboxylic acid residues having up to 20 carbon atoms; and (iii) 0 to 10 mole % of aliphatic dicarboxylic acid residues having up to 16 carbon atoms; and (b) a glycol component comprising: (i) 1 to 99 mole % of 2,2,4,4-tetramethyl-1,3 -cyclobutanediol residues; and (ii) 1 to 99 mole % of cyclohexanedimethanol residues; and (II) at least one thermal stabilizer chosen from at least one of alkyl phosphate esters, aryl phosphate esters, mixed alkyl aryl phosphate esters, reaction products thereof, and mixtures thereof; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the glycol component is 100 mole %.
US08193299B2 Biodegradable aliphatic-aromatic copolyester
Biodegradable aliphatic/aromatic copolyester comprising: A) an acid component comprising repeating units of: 1) 53 to 54 mol % of an aromatic carboxylic acid; 2) 47 to 36 mol % of an aliphatic acid at least 50% of which is azelaic acid; B) a diol component selected from the group consisting of C3, C4 and C6 diols; said AAPE being disintegrated according to the Standard ISO 20200 in 90 days.
US08193286B2 Acrylic star polymer
A method for obtaining a star polymer having a controlled ratio of a weight average molecular weight of the star polymer to a number average molecular weight of the star polymer, containing the steps of anionically polymerizing a (meth)acrylic ester having an alicyclic skeleton and a lactone ring in the presence of an anionic polymerization initiator to synthesize an arm polymer, reacting the arm polymer with a polyfunctional coupling agent, and reacting with an anionic polymerizable monomer.
US08193281B2 Copolymerizable surfactants (2)
The invention is directed to the use of maleic esters selected from compounds of formulae (I) and (II) as copolymerizable emulsifiers in the emulsion polymerization of olefinically unsaturated monomers, in which A is an alkyl group having 3 to 40 carbon atoms; X and Z independently are hydrogen or methyl; M is hydrogen, an alkali metal, alkaline earth metal, or an ammonium or other amine salt; and n and p independently are numbers in the range from 0 to 40.
US08193276B2 Fluorocopolymer and water and oil proofing composition, and processes for their production
A fluorocopolymer capable of exhibiting excellent water and oil resistance even with its perfluoroalkyl group being a short chain, and a water and oil proofing composition containing it, are provided.A water and oil proofing composition containing a fluorocopolymer (A) comprising from 40 to 98 mass % of polymerized units (a′) having a C1-6 perfluoroalkyl group, from 1 to 50 mass % of polymerized units (b′) having an alkylene oxide and from 1 to 10 mass % of polymerized units (c′) based on a monomer represented by CH2═C(COOH)-Q-COOH (wherein Q is a C1-4 alkylene group, etc.).
US08193273B2 Thermoplastic elastomers for adhesion to polyamide
A thermoplastic elastomer (TPE) is disclosed which has excellent compression set and adhesion to both polyamide 6 and polyamide 6,6 for use in two-part component polymer structures.
US08193272B2 Flame-retardant high impact vinyl aromatic resin composition having good fluidity
The flame-retardant high impact vinyl aromatic resin composition of the present invention comprises (A) about 100 parts by weight of a rubber modified vinyl aromatic resin; (B) about 1 to about 30 parts by weight of a brominated diphenyl ethane mixture; and (C) about 1 to about 10 parts by weight of antimony oxide. The resin composition can have excellent fluidity as well as high impact strength and can provide a flame-retardant high impact vinyl aromatic resin composition having excellent workability and mechanical properties.
US08193271B2 Process for preparing an aqueous polymer composition using water-soluble free radical chain regulators
Process for preparing an aqueous polymer composition using water-soluble free radical chain regulators.
US08193268B2 Hot-vulcanizable polyorganosiloxane compositions useful particularly for manufacturing electrical cables or wires
A polyorganosiloxane composition that can be vulcanized at high temperature to a silicone elastomer, useful in the field of the manufacture of electrical wires or cables having an improved fire performance is provided. The composition includes a semi-reinforcing filler chosen from the group composed of:—calcined kaolin powders, preferably that have undergone a chemical surface treatment;—talc;—calcium carbonate that may or may not have been surface-treated, for example with vinylsilanes, aminosilanes or (reactive or unreactive) silicone oils; and mixtures thereof.
US08193265B2 Rubber composition and tires made by using the same
The rubber composition of the present invention is prepared by mixing 10 to 200 parts by mass of silica and 1 to 30 parts by mass of a silane compound having sulfur atom, which has a specific structure such that an organooxysilyl group is present at both ends of the molecule and sulfide or a polysulfide is present at the central portion of the molecule, with 100 parts by mass of a polymer. The rubber composition of the present invention has a small viscosity in the unvulcanized condition and provides excellent dispersion of silica. When this composition is used as a material for a tire tread, a tire exhibiting excellent abrasion resistance, a small rolling resistance and excellent braking property and steering stability on wet roads, can be obtained.
US08193260B2 Stabilization of polymers with styrenated-p-cresols
Disclosed herein is a process for the preparation of a mixture of styrenated p-cresol species that is liquid at room temperature and has a viscosity of less than 40,000 cps at 25° C., wherein said process affords 2,6-distyrenated p-cresol assaying at 70% minimum by GC area percent, comprising reacting styrene with p-cresol at a molar ratio of 1.85 to 2.1:1, respectively, in the presence of an acid catalyst at elevated temperature, wherein said mixture comprises monostyrenated-p-cresol, distyrenated-p-cresol, and tristyrenated-p-cresol and exhibits an acid number of less than 0.1 mg KOH/gram.
US08193258B2 Sealant composition
A sealant composition is provided. The sealant composition includes (a) an oligomer including an unsaturated mono-carboxylic acid modified bisphenol A epoxy resin and an unsaturated mono-carboxylic acid modified bisphenol F epoxy resin, wherein an equivalence ratio of the bisphenol A epoxy resin to the bisphenol F epoxy resin is 0.05:0.95 to 0.3:0.7, the bisphenol A epoxy resin has a melting point higher than 40° C. and the bisphenol F epoxy resin has a melting point lower than 40° C.; (b) an epoxy resin having at least two or more than two epoxy groups; and (c) a photoinitiator.
US08193249B2 Triptolide analogs for the treatment of autoimmune and inflammatory disorders
The present invention provides synthetic methods and compositions for treatment of autoimmune and anti-inflammatory disorders comprising administering an effective amount of a derivative of triptolide alone or in combination or alternation with other anti-autoimmune or anti-inflammatory compounds.
US08193248B2 Contraceptive composition
The present invention relates to a contraceptive composition including an effective amount of a dendrimer compound including one or more naphthyl disulphonic acid surface groups, or a pharmaceutically acceptable salt or solvate of the dendrimer compound; and a pharmaceutically acceptable carrier, excipient and/or diluent therefor. The contraceptive composition may also exhibit antimicrobial activity. The invention also relates to a method of selectively reducing or preventing conception in a female animal, including a human, which method includes administering to the animal an effective amount of a contraceptive composition which composition includes an effective amount of a dendrimer compound including one or more naphthyl disulphonic acid surface groups, or a pharmaceutically acceptable salt or solvate of the dendrimer compound; and a pharmaceutically acceptable carrier, excipient and/or diluent therefor.
US08193241B2 Discodermolide analogues and methods of their use
6- and 7-substituted coumarin and related 6- and 7-substituted 1H-quinolin-2-one compounds, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the 7-substituted coumarin and related 7-substituted 1H-quinolin-2-one compounds mimic or exceed the high level of pharmacological activity of discodermolide. In other embodiments, their preparation involves more readily available materials, higher yield processes and/or simpler synthetic sequences. In yet other embodiments, the compounds of the invention represent structurally simpler, therapeutically active analogues of discodermolide than heretofore known and may be useful as microtubule stabilizers and, inter alia, for treating and/or preventing cancer and other diseases, disorders, and/or conditions mediated by the stabilization of microtubules.
US08193240B2 Compositions and methods for reducing or preventing obesity
Compositions useful for weight management in an animal are disclosed. The compositions comprise one or more isoflavones or isoflavone metabolites, and in some embodiments include conjugated linoleic acid, and/or L-carnitine. Also disclosed are methods useful for weight management in an animal utilizing compositions comprising one or more isoflavones, conjugated linoleic acid, and/or L-carnitine. Preferably, the compositions and methods employ a combination of one or more isoflavones, or a combination of one or more isoflavones in conjunction with conjugated linoleic acid, and L-carnitine.
US08193239B2 Substituted 1-cyanoethylheterocyclylcarboxamide compounds
The present invention provides compounds of formula (I) in which y, m, n, R1, R2 and Q are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.
US08193238B2 Inhibition of microtubule protrusion in cancer cells
The present invention generally concerns microtubule protrusions in cancer cells, including detached cancer cells, and inhibition of the protrusions. In particular aspects, the inhibition of the protrusions interferes with attachment of the cell to a vessel wall, and in further aspects the cell is killed by forcing it to enter capillaries and be destroyed, for example by shearing. Inhibition by a variety of agents and methods is contemplated.
US08193237B2 Indole derivative having IκB kinase β inhibitory activity
Disclosed is a compound represented by the general formula (1) or a salt thereof. The compound or a salt thereof has an inhibitory activity on IKKβ and is therefore useful as preventive and/or therapeutic agent for a disease associated with IKKβ. In the formula, R1 represents a hydrogen atom, a lower alkyl group, an aryl group, a hydroxy group, or the like; R2 represents a halogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, or the like; and m represents 0, 1, 2, or the like.
US08193236B2 Indolylmaleimide derivatives processes for their production and pharmaceutical compositions
A compound of formula (I) wherein R denotes another heterocylic residue and wherein Ra, Rb, Rc, Rd and Re, are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.
US08193233B2 Anti-fungal formulation
Provided herein are compositions and formulations comprising an antifungal agent. Pharmaceutical compositions comprising luliconazole in an amount effective for the treatment of onychomycosis are provided. Also provided are methods for treating dermatomycoses and onychomycosis using the compositions and formulations.
US08193231B2 Compositions comprising N3 alkylated benzimidazole derivatives as MEK inhibitors and methods of use thereof
Disclosed are pharmaceutical compositions comprising 6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide, or a pharmaceutically acceptable salt thereof. Also disclosed are methods of using such compositions for inhibiting abnormal cell growth or treating hyperproliferative diseases in mammals.
US08193230B2 Compositions comprising N3 alkylated benzimidazole derivatives as MEK inhibitors and methods of use thereof
Disclosed are pharmaceutical compositions comprising 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide, or a pharmaceutically acceptable salt thereof. Also disclosed are methods of using such compositions for inhibiting abnormal cell growth or treating hyperproliferative diseases in mammals.
US08193229B2 Method of treatment using N3 alkylated benzimidazole derivatives as MEK inhibitors
Disclosed are methods of treating a hyperproliferative disorder or a disease related to vasculogenesis or angiogenesis in a mammal, comprising administering to said mammal an effective amount of a compound of the formula or a pharmaceutically accepted salt thereof, wherein A, R1, R2, R7, R8, and R9 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals.
US08193227B2 HIV protease inhibiting compounds
A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
US08193221B2 Insecticidal compounds
A compound of formula (I) wherein A1, A2, A3, A4, R1, R2, R3 and R4 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, nematicidal or molluscicidal compositions comprising them and to methods of using them to combat and control insect, acarine, nematode or mollusc pests.
US08193220B1 Method of changing muscle lengths with anesthetic drugs
According to one aspect, the fibers of a muscle to be shortened or lengthened are exposed to a local anesthetic drug such as bupivacaine. The concentration and volume of the local anesthetic drug are sufficient to causes the muscle fibers to be damaged by the myotoxicity of the drug. The muscle is then kept at a different length, shorter or longer, during the ensuing period of muscle fiber regeneration, resulting in a shortened or lengthened muscle. In one embodiment, the shortened length of the treated muscle improved the position and the movement of the eye to which it was attached.
US08193219B2 Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed.
US08193215B2 Thieno[2 3-b]pyridines as potassium channel inhibitors
The invention provides compounds of the formula: wherein R1 is aryl, heteroaryl, cycloalkyl or alkyl; R2 is H, alkyl, nitro, CO2R7, CONR5R6 or halo; R3 and R4 are H, NR5R6, NC(O)R7, halo, trifluromethyl, alkyl, CONR5R6, CO2R7, nitrile or alkoxy; R5 and R6 may be the same or different and may be H, alkyl, aryl, heteroaryl or cycloalkyl; or R5 and R6 may together form a saturated, unsaturated or partially saturated 4 to 7 member ring, wherein said ring may optionally comprise one or more further heteroatoms selected from N, O or S; R7 is H or alkyl; A is H, halo, or a group of formula X-L-Y; X is O, S or NR8; R8 is H or alkyl; L is (CH2)n, where n is 0, 1, 2, 3 or 4; and Y is aryl, a heterocyclic group, alkyl, alkenyl or cycloalkyl; the products of mono- and di-oxidation of sulphur and/or mono-oxidation of nitrogen moieties in compounds of formula I; or a pharmaceutically acceptable salt thereof. These compounds find use as inhibitors of potassium ion channels and thus are useful in the treatment of various conditions including arrhythmia and type-2 diabetes mellitus.
US08193213B2 Spermicidal and/or antifungal composition and methods of using the same
Hexahydroindenopyridine compounds are provided which act as spermicides and/or fungicides, spermicidal and/or fungicidal compositions containing the same, and methods for killing motile sperm and/or fungi using the compounds and compositions.
US08193211B2 Controlled release compositions of gamma-hydroxybutyrate
The present invention is directed to oral pulse-release pharmaceutical dosage form containing an immediate release component of gamma-hydroxybutyric acid, and one or more delayed/controlled release components of gamma-hydroxybutyric acid.
US08193208B2 Fused and spirocycle compounds and the use thereof
The invention relates to fused and spirocycle compounds of Formula I: or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein R1, R2, Q1-Q3, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
US08193204B2 Solid forms of (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1- (4-chloro-2-(3-methyl-1H-pyrazol-1-YL)phenyl)2,2,2-trifluoroethoxy)-pyrimidin-4-YL)phenyl)propanoate and methods of their use
Solid forms of (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate and salts thereof are disclosed.
US08193197B2 Compositions and methods for inhibition of the JAK pathway
The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases are therapeutically useful.
US08193191B2 Urotensin II receptor antagonists
The invention is directed to Urotensin II antagonists. More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating Urotensin-II mediated disorders. Pharmaceutical and veterinary compositions and methods of treating cardiovascular disorders and various other disease states or conditions using compounds of the invention are also described.
US08193188B2 Methods of using pyridodihydropyrazinones
Disclosed are pyridodihydropyrazinone compounds, processes for preparing them and their use as pharmaceutical compositions. The compounds according to the invention correspond to general formula (I), while the groups L, R1, R2, R3, R4 and R5 may have the meanings given in the claims and specification.
US08193183B2 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists
The present invention is directed to a compound of Formula (I) wherein Cy1, Cy2, L1, L2, and R1 are as defined herein, a pharmaceutical composition comprising a pharmaceutically effective amount of one or more compounds according to Formula (I) in admixture with a pharmaceutically acceptable carrier, and a method of treating a patient suffering from a PGD2-mediated disorder including, but not limited to, allergic disease (such as allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma and food allergy), systemic mastocytosis, disorders accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, bronchitis, urticaria, eczema, diseases accompanied by itch (such as atopic dermatitis and urticaria), diseases (such as cataract, retinal detachment, inflammation, infection and sleeping disorders) which is generated secondarily as a result of behavior accompanied by itch (such as scratching and beating), inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, ulcerative colitis and the like by administering to said patient a pharmaceutically effective amount of a compound according to Formula (I).
US08193181B2 Xinafoate salt of N4-(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine
The present invention relates to the xinafoate salt of N4-[(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy)phenyl]-2,4-pyrimidinediamine. This compound is a suitable drug substance and is useful in the treatment of conditions including asthma.
US08193180B2 N-amino tetrahydrothiazine derivatives, method of manufacture and use
This invention comprises the innovative synthesis of N-amino tetrahydrothiazine free bases and their salts. This invention further comprises the use of the derivatives and their therapeutic application as anticancer agents. Further this invention comprises their manufacture and use.
US08193179B2 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives
Antibacterial compounds including 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives are provided, and methods of treatment or prevention of bacterial infection with such compounds are provided.
US08193175B2 Ruthenium complexes for treating cancers
The invention concerns uses or methods for treating proliferative pathologies, in particular cancers, using ruthenium compounds and compositions containing the same. The invention also concerns novel ruthenium compounds, as well as their preparation method.
US08193166B2 Epimerized derivatives of K5 polysaccharide with a very high degree of sulfation
A new method is described for the oversulfation of epiK5-N-sulfate to obtain an epiK5-amine-O-oversulfate with very high sulfation degree which, by subsequent N-sulfation, provides new epiK5-N,O-oversulfate-derivatives with a sulfation degree of at least 4, basically free of activity on the coagulation parameters and useful in the cosmetic or pharmaceutical field. Also described are new low molecular weight epiK5-N-sulfates useful as intermediates in the preparation of the corresponding LMW-epiK5-N,O-oversulfate-derivatives.
US08193164B2 Organic compounds
A compound of formula (I), or stereoisomers or pharmaceutically acceptable salts thereof, wherein, R1a, R1b, R2a, R2b, U1, U2, X1, X2 and L are as defined herein.
US08193162B2 Human liver regeneration associated protein and the use thereof
This invention provides a novel human liver regeneration associated protein hLRTM4 and the polynucleotide which encodes the hLRTM4 protein. Furthermore, this invention provides a method of preparing and using hLRTM4 protein, and its polynucleotides. hLRTM4 protein can be used to treat liver injury, and its antagonists (e.g. antisense nucleic acids and antibodies) can be used to treat hepatocellular carcinoma. This invention also provides the corresponding pharmaceutical compositions.
US08193161B2 Compositions comprising cardiac stem cells overexpressing specific micrornas and methods of their use in repairing damaged myocardium
The invention provides compositions comprising modified stem cells containing a transgene that affects the expression of at least one gene that inhibits or promotes cardiomyogenesis. In particular, the invention discloses compositions comprising cardiac stem cells, wherein said cardiac stem cells comprise a transgene encoding a microRNA. The compositions of the invention find use in the treatment of cardiovascular disorders, such as myocardial infarction. Methods of repairing damaged myocardium in a subject using the modified stem cells are also disclosed.
US08193159B2 MCP-1 binding nucleic acids
The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group comprising type 1A nucleic acids, type 1B nucleic acids, type 2 nucleic acids, type 3 nucleic acids, type 4 nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ. ID. No. 87 to 115.
US08193155B2 Method and compositions for treating skin
A skin care composition comprising at least one keratinocyte CLOCK or PER1 gene activator and at least one DNA repair enzyme; a method for inhibiting damage to human keratinocytes due to environmental aggressors by applying a composition comprising at least one keratinocyte CLOCK or PER1 gene activator and at least one DNA repair enzyme; and a method for repairing DNA damage in human keratinocytes.
US08193154B2 Oligopeptide tyrosinase inhibitors and uses thereof
Disclosed are peptides that inhibit the enzymatic activity of tyrosinase, as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. Peptide sequences disclosed include KFEKKFEK (SEQ ID NO: 1) and YRSRKYSSWY (SEQ ID NO: 2).
US08193153B2 Trophic factor for the treatment of retinal degenerative diseases
This invention relates to methods and compositions for detection and treatment of retinal degenerative diseases. In particular, the invention relates to polypeptides that can protect against cone degeneration, nucleic acid molecules that encode such polypeptides, and antibodies that recognize said polypeptides.
US08193151B2 Methods for treating atrial or ventricular arrhythmias
The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation.
US08193145B2 Laminins, derivatives, and compositions including same and methods for their therapeutic use
In various embodiments, the present disclosure provides a method of treating a subject using laminin or a composition that includes laminin. In one embodiment, the method is used to enhance muscle regeneration, maintenance, or repair in a subject. In another embodiment, the method is used to promote wound healing. The method, in yet another embodiment, is used to prevent or reduce muscle damage or injury. In specific implementations of these methods, the laminin or composition that includes laminin is administered in a therapeutically effective amount. In some implementations, the laminin is a complete laminin protein. In other implementations, the laminin is a laminin fragment, a laminin derivative, or a laminin analogue.
US08193143B2 Laundry detergent composition comprising a highly water-soluble carboxymethyl cellulose particle
A solid laundry detergent composition having: (a) detersive surfactant; and (b) from 0.05 wt % to 20 wt % carboxymethyl cellulose particle, wherein the carboxymethyl cellulose particle: (i) from 70 wt % to 98 wt % carboxymethyl cellulose having an average degree of carboxymethyl substitution of from 0.6 to 0.9; (ii) from 2 wt % to 12 wt % water; (iii) optionally from 0 wt % to 4 wt % sodium glycolate; and (iv) optionally from 0 wt % to 4 wt % sodium chloride.
US08193142B2 Composition
A cleaning composition comprises a dispersion. The dispersion includes an acidic aqueous phase and a suspended particle. The particle is coated with an acid stable coating.
US08193141B2 Fabric care compositions, process of making, and method of use comprising primary particles comprising cationic polymer and anionic surfactants
The instant disclosure relates to stable color maintenance and/or rejuvenation compositions comprising at least one cationic polymer and anionic surfactant, and methods for providing the same.
US08193139B2 Cleaning formulations for machine dishwashing comprising hydrophilically modified polycarboxylates
The invention relates to a phosphate-free cleaning formulation for machine dishwashing, comprising as components: a) 1 to 20% by weight of copolymers of a1) 50 to 93 mol % acrylic acid and/or of a water-soluble salt of acrylic acid, a2) 5 to 30 mol % of methacrylic acid and/or of a water-soluble salt of methacrylic acid and a3) 2 to 20 mol % of at least one nonionic monomer of the formula (I), b) 1 to 50% by weight of complexing agents chosen from the group consisting of glycine-N,N-diacetic acid derivatives and glutamic acid-N,N-diacetic acid and salts thereof, c) 1 to 15% by weight of low-foaming nonionic surfactants, d) 0 to 30% by weight of bleaches and optionally bleach activators, e) 0 to 60% by weight of further builders, f) 0 to 8% by weight of enzymes, g) 0 to 50% by weight of one or more further additives, such as anionic or zwitterionic surfactants, bleach catalysts, alkali carriers, corrosion inhibitors, antifoams, dyes, fragrances, fillers, organic solvents and water, where the sum of components a) to g) is 100% by weight.
US08193135B2 Ethylene-propylene copolymers suitable for the modification of lubricating oils and process for the preparation thereof
Process for the preparation of viscosity index improver (V.I.I.) additives of lubricating oils which comprises a mixing treatment under high shear conditions of a composition comprising: (i) one or more EP(D)M polymers (ii) one or more polyvinylarene/conjugated hydrogenated polydiene/polyvinylarene block copolymers; and (iii) lubricating oil, (ii) being present in a concentration of 1.5 to 20% by weight whereas (iii) is present in a concentration ranging from 1.5 to 45% by weight.
US08193134B2 Thickened spreadable warming lubricant
A substantially anhydrous, thickened, spreadable, warming lubricant composition comprising a mixture of glycerin, polyhydric alcohol, a non-ionic surfactant, and a Carbomer thickener, the surfactant improving wetting and spreadability of the composition on skin and latex, and the thickener providing a creamy rich feel to the composition, such that the composition can be applied to skin or a condom and provide an optimal warming effect upon contact with ambient moisture during use and such that the composition can be added to a condom package and, over the course of a week, spread and coat nearly the entire internal and external surfaces of the condom.
US08193133B2 Process for preparing fine powder polyurea and greases therefrom
Polyurea compounds are prepared by reacting amines and polyisoyanates in the presence of a liquid diluent in a high-pressure impingement mixing device under conditions sufficient to produce polyurea compounds having the consistency of a powder and in which diluent is dispersed.
US08193129B2 Refrigerator oil, compressor oil composition, hydraulic fluid composition, metalworking fluid composition, heat treatment oil composition, lubricant composition for machine tool and lubricant composition
The present invention provides a refrigerating machine oil, a compressor oil composition, a hydraulic oil composition, a metalworking oil composition, a heat treating oil composition, a lubricating oil composition for machine tools and a lubricating oil composition which comprise a lubricating oil base oil having % CA of not more than 2, % CP/% CN of not less than 6 and an iodine value of not more than 2.5.
US08193122B2 Superconductor fabrication
A seed crystal for the fabrication of a superconductor is grown from a rare-earth oxide having the basic formula XwZtBaxCuyOz, X comprising at least one rare-earth element and Z being a dopant which raises the peritectic decomposition temperature (Tp) of the oxide. In a preferred embodiment, the dopant is Mg. Use of this rare-earth oxide material for seed crystals increases the temperature at which cold-seeding can be performed and thus enables the growth of a wider range of bulk superconductor materials by this process.
US08193121B2 2-(3-alkylthiobenzoyl)cyclohexanediones and their use as herbicides
2-(3-Alkylthiobenzoyl)cyclohexanediones of the formula (I) are described as herbicides. In this formula (I), X, Y, R1 to R8 represent radicals such as hydrogen, organic radicals such as alkyl and alkoxy.
US08193118B2 Insecticidal substituted benzylamino heterocyclic and heteroaryl derivatives
Certain substituted benzylamino heterocyclic and heteroaryl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula (I): wherein R, R1, R2, R3, and R4 are fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula (I), and optionally, an effective amount of at least one of an additional compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.
US08193116B2 Heat-sensitive recording material
To provide a heat-sensitive recording material including a substrate; a heat-sensitive color-developing layer over the substrate, the heat-sensitive color-developing layer containing a leuco dye and a developer; a first protective layer over the heat-sensitive color-developing layer, the first protective layer containing a water-soluble resin and a crosslinking agent; and a second protective layer over the first protective layer, the second protective layer containing a water-soluble resin, a crosslinking agent and a pigment, wherein the heat-sensitive color-developing layer, the first protective layer and the second protective layer are formed simultaneously by curtain coating method, and the second protective layer contains diacetone-modified polyvinyl alcohol and acrylic resin or maleic acid copolymer resin.
US08193115B2 Method for solidifying high moisture sludge
A method for treating a high water content sludge is disclosed, where the method includes mixing into the high water content sludge, an effective amount of an ash composition. The effective amount of the ash composition is sufficient to convert a portion of the sludge and the ash composition into a treated sludge including an amount of a solidifying matrix to impart properties to a depth of the sludge sufficient to support commercial construction equipment. A treated sludge and sludge pits are also disclosed as is the ash composition used to form the treated sludge.
US08193110B2 Refractory carbon-bonded magnesia brick and process for producing it
The invention relates to a refractory, ceramically fired, carbon-bonded magnesia brick whose matrix is more than 70% by weight, in particular from 80 to 98% by weight, of MgO grains and also a carbon framework binder matrix resulting from carbonization, and pores, wherein the MgO grains are fixed by means of carbon bonding of the carbon framework and at least 30%, in particular from 50 to 100%, of the MgO grains have at least one sintering bridge resulting from the ceramic firing.
US08193105B2 Allergen barrier fabric
An allergen-barrier fabric and method of producing the same is provided. The fabric is formed from weaving yarns and processed such that the resulting pore size is less than approximately 1 micron. The finished fabric may also include exhibit consistent pore to pore variability. The finished fabric may exhibit an MVTR of at least 7,000 and a hydrostatic resistance of at least 10,000 mm.
US08193100B2 Exposure mask manufacturing method, drawing apparatus, semiconductor device manufacturing method, and mask blanks product
A method of manufacturing an exposure mask includes generating or preparing flatness variation data relating to a mask blanks substrate to be processed into an exposure mask, the flatness variation data being data relating to change of flatness of the mask blank substrate caused when the mask blank substrate is chucked by a chuck unit of an exposure apparatus, generating position correction data of a pattern to be drawn on the mask blanks substrate based on the flatness variation data such that a mask pattern of the exposure mask comes to a predetermined position in a state that the exposure mask is chucked by the chuck unit, and drawing a pattern on the mask blanks substrate, the drawing the pattern including drawing the pattern with correcting a drawing position of the pattern and inputting drawing data corresponding to the pattern and the position correction data into a drawing apparatus.
US08193097B2 Plasma processing apparatus and impedance adjustment method
A plasma processing apparatus, for performing a plasma processing on a substrate to be processed by generating a plasma of the processing gas in an evacuable processing chamber, includes an impedance adjusting mechanism. The impedance adjusting mechanism is provided with a resonance circuit formed to allow a radio frequency current to flow into the first electrode; a variable impedance unit installed on a power feed line to the first electrode; a detector for detecting an apparatus state to be used to search a resonance point of the resonance circuit; and a controller for searching a resonance point of the resonance circuit by detecting a signal of the apparatus state of the detector while varying a value of the variable impedance unit in a state where the plasma is formed and then adjusting the value of the variable impedance unit at the resonance point to a reference value.
US08193095B2 Method for forming silicon trench
A method for forming a silicon trench, comprises the steps of: defining an etching area at a silicon substrate; forming metal catalysts at the surface of the etching area; immersing the silicon substrate in a first etching solution thereby forming anisotropic silicon nanostructures in the etching area; immersing the silicon substrate in a second etching solution thereby resulting in the silicon nanostructures being side-etched and detached from the silicon substrate, thus forming the silicon trench.
US08193094B2 Post CMP planarization by cluster ION beam etch
The embodiments of mechanisms described enables improved planarity of substrates, which is crucial for patterning and device yield improvement. Chemical-mechanical polishing (CMP) is used to remove film to planarize the substrate before the final thickness is reached or before all removal film is polished. The substrate is then measured for its topography and film thickness. The topography and thickness data are used by the gas cluster ion beam (GCIB) etch tool to determine how much film to remove on a particular location. GCIB etch enables removal of final layer to meet the requirements of substrate uniformity and thickness target. The mechanisms enable improved planarity to meet the requirement of advanced processing technologies.
US08193093B2 Thru silicon enabled die stacking scheme
A die to die bonding system and method includes an upper die having a front side, a back side, and a fully filled thru silicon via, a portion of the fully filled thru silicon via protruding from the back side of the upper die. A lower die includes a front side, a back side, and a partially filled thru silicon via formed to define a via opening exposed to the front side of the die, a portion of the partially filled thru silicon via protruding from the back side of the lower die. An interconnect bonds an outer surface of the protruding portion of the upper die thru silicon via with an inner surface of via opening in the lower die.
US08193091B2 Resin encapsulated semiconductor device and method for manufacturing the same
The present invention includes a die pad; signal leads, ground connection leads connected to the die pad; a semiconductor chip including electrode pads for grounding; metal thin wires, and an encapsulating resin for encapsulating the die pad and the semiconductor chip and encapsulating the signal leads and the ground connection lead such that lower portions of the signal leads and the ground connection lead are exposed as external terminals. The ground connection lead is connected to the electrode pad for grounding, so that the resin-encapsulated semiconductor device is electrically stabilized. Furthermore, interference between high frequency signals passing through the signal leads can be suppressed by the die pad and the ground connection leads.
US08193087B2 Process for improving copper line cap formation
An integrated circuit includes a semiconductor substrate, a low-k dielectric layer over the semiconductor substrate, a first opening in the low-k dielectric layer, and a first diffusion barrier layer in the first opening covering the low-k dielectric layer in the first opening, wherein the first diffusion barrier layer has a bottom portion connected to sidewall portions, and wherein the sidewall portions have top surfaces close to a top surface of the low-k dielectric layer. The integrated circuit further includes a conductive line filling the first opening wherein the conductive line has a top surface lower than the top surfaces of the sidewall portions of the diffusion barrier layer, and a metal cap on the conductive line and only within a region directly over the conductive line.
US08193085B2 Method for fabricating flip-attached and underfilled semiconductor devices
A semiconductor device (1700), which comprises a workpiece (1201) with an outline (1711) and a plurality of contact pads (1205) and further an external part (1701) with a plurality of terminal pads (1702). This part is spaced from the workpiece, and the terminal pads are aligned with the workpiece contact pads, respectively. A reflow element (1203) interconnects each of the contact pads with its respective terminal pad. Thermoplastic material (1204) fills the space between the workpiece and the part; this material adheres to the workpiece, the part and the reflow elements. Further, the material has an outline (1711) substantially in line with the outline of the workpiece, and fills the space (1707) substantially without voids. Due to the thermoplastic character of the filling material, the finished device can be reworked, when the temperature range for reflowing the reflow elements is reached.
US08193084B2 Method of manufacturing semiconductor device
When a bump electrode is formed on an opening formed in a semiconductor substrate, the invention prevents a void that is caused by gas trapped in the opening. A method of manufacturing a semiconductor device of the invention includes forming a first wiring on a main surface of a semiconductor substrate, forming an opening in the semiconductor substrate from the back surface to the main surface so as to expose the back surface of the first wiring, forming a second wiring connected to the back surface of the first wiring and extending from inside the opening onto the back surface of the semiconductor substrate, forming a solder layer connected to part of the second wiring on the bottom of the opening and extending from inside the opening onto the back surface of the semiconductor substrate, and forming a bump electrode on the opening by reflowing the solder layer.
US08193079B2 Method for conductivity control of (Al,In,Ga,B)N
A method of controlled p-type conductivity in (Al,In,Ga,B)N semiconductor crystals. Examples include {10 11} GaN films deposited on {100} MgAl2O4 spinel substrate miscut in the <011> direction. Mg atoms may be intentionally incorporated in the growing semipolar nitride thin film to introduce available electronic states in the band structure of the semiconductor crystal, resulting in p-type conductivity. Other impurity atoms, such as Zn or C, which result in a similar introduction of suitable electronic states, may also be used.
US08193078B2 Method of integrating epitaxial film onto assembly substrate
A method of growing an epitaxial film and transferring it to an assembly substrate is disclosed. The film growth and transfer are made using an epitaxy lateral overgrowth technique. The formed epitaxial film on an assembly substrate can be further processed to form devices such as solar cell, light emitting diode, and other devices and assembled into higher integration of desired applications.
US08193075B2 Remote hydrogen plasma with ion filter for terminating silicon dangling bonds
Apparatus and methods for repairing silicon dangling bonds resulting from semiconductor processing are disclosed. The silicon dangling bonds can be repaired by introducing hydrogen radicals with substantially no hydrogen ions into the processing chamber to react with the silicon dangling bonds, eliminating them.
US08193072B2 Semiconductor wafer coat layers and methods therefor
Formulations and processes for forming wafer coat layers are disclosed. In one embodiment, an organic surface protectant is incorporated into a wafer coat formulation deposited onto a semiconductor wafer prior to the laser scribe operation. Upon removal of the wafer coat layer, the organic surface protectant remains on the bumps and thereby prevents oxidation of the bumps between die prep and chip and attach. In an alternative embodiment, an ultraviolet light absorber is added to the wafer coat formulation to enhance the wafer coat layer's energy absorption and thereby improve the laser's ability to ablate the wafer coat layer. In an alternative embodiment, a conformal wafer coat layer is deposited on the wafer and die bumps, thereby reducing wafer coat layer thickness variations that can impact the laser scribing ability.
US08193071B2 Method for manufacturing semiconductor device
The manufacturing method includes attaching a single crystal semiconductor layer to a supporting substrate, detecting a position of a deficiency region in the single crystal semiconductor layer, forming a non-single-crystal semiconductor layer over the single crystal semiconductor layer, selectively improving crystallinity of a portion of the non-single-crystal semiconductor layer based on the position of the deficiency region, the portion being overlapped with the deficiency region, and planarizing the non-single-crystal semiconductor layer over the supporting substrate.
US08193068B2 Method of manufacturing SOI substrate
To provide an SOI substrate with an SOI layer that can be put into practical use, even when a substrate with a low allowable temperature limit such as a glass substrate is used, and to provide a semiconductor substrate formed using such an SOI substrate. In order to bond a single-crystalline semiconductor substrate to a base substrate such as a glass substrate, a silicon oxide film formed by CVD with organic silane as a source material is used as a bonding layer, for example. Accordingly, an SOL substrate with a strong bond portion can be formed even when a substrate with an allowable temperature limit of less than or equal to 700° C. such as a glass substrate is used. A semiconductor layer separated from the single-crystalline semiconductor substrate is irradiated with a laser beam so that the surface of the semiconductor layer is planarized and the crystallinity thereof is recovered.
US08193061B2 Polysilicon control etch-back indicator
This invention discloses a semiconductor wafer for manufacturing electronic circuit thereon. The semiconductor substrate further includes an etch-back indicator that includes trenches of different sizes having polysilicon filled in the trenches and then completely removed from some of the trenches of greater planar trench dimensions and the polysilicon still remaining in a bottom portion in some of the trenches having smaller planar trench dimensions.
US08193060B2 Method of manufacturing a semiconductor device
Provided is a method for manufacturing a semiconductor device. A well region formed on a semiconductor substrate includes a plurality of trench regions, and a source electrode is connected to a source region formed on a substrate surface between the trench regions. Adjacently to the source region, a high concentration region is formed, which is brought into butting contact with the source electrode together with the source region, whereby a substrate potential is fixed. A drain region is formed at a bottom portion of the trench region, whose potential is taken to the substrate surface by a drain electrode buried inside the trench region. An arbitrary voltage is applied to a gate electrode, and the drain electrode, whereby carriers flow from the source region to the drain region and the semiconductor device is in an on-state.
US08193058B2 Method of manufacturing semiconductor device
A semiconductor device including a semiconductor substrate; a plurality of memory cell transistors aligned in a predetermined direction on the semiconductor substrate, each memory cell transistor provided with a first gate electrode including a floating gate electrode comprising a polycrystalline silicon layer of a first thickness, a control gate electrode provided above the floating gate electrode, and an inter-gate insulating film between the floating and the control gate electrode; a pair of select gate transistors on the semiconductor substrate with a pair of second gate electrodes neighboring in alignment with the first gate electrode, each second gate electrode including a lower-layer gate electrode comprising the polycrystalline silicon layer of the first thickness, an upper-layer gate electrode provided above the lower-layer gate electrode; a polyplug of the first thickness situated between the second gate electrodes of the pair of select gate transistors; and a metal plug provided on the polyplug.
US08193056B2 Method of manufacturing semiconductor device
According to one embodiment, a method of fabricating a semiconductor device is disclosed. The method includes the steps of: forming a tunnel insulating film on a semiconductor substrate; forming a floating gate electrode on the tunnel insulating film; and forming a silicon nitride film including a low-density silicon nitride film and a high-density silicon nitride film on the floating gate electrode. The method also includes the steps of: forming an isolation trench thereby to expose the low-density silicon nitride film exposed at least in a portion of a side surface of the isolation trench; forming an isolating insulating film covering an internal surface of the isolation trench; removing the silicon nitride film; and forming an interelectrode insulating film and a control gate electrode both covering the floating gate electrode and the isolating insulating film.
US08193055B1 Method of forming memory with floating gates including self-aligned metal nanodots using a polymer solution
Techniques are provided for fabricating memory with metal nanodots as charge-storing elements. In an example approach, metal salt ions are added to a core of a copolymer solution. A metal salt reduction causes the metal atoms to aggregate in the core, forming a metal nanodot. The copolymer solution is applied to a gate oxide on a substrate using spin coating or dip coating. Due to the copolymer configuration, the nanodots are held in a uniform 2D grid on the gate oxide. The polymers are selected to provide a desired nanodot size and spacing between nanodots. A polymer cure and removal process leaves the nanodots on the gate oxide. In a configuration using a control gate over a high-k dielectric floating gate which includes the nanodots, the control gates may be separated by etching while the floating gate dielectric extends uninterrupted since the nanodots are electrically isolated from one another.
US08193047B2 Semiconductor device having sufficient process margin and method of forming same
According to some embodiments of the invention, a substrate doped with a P type impurity is provided. An N type impurity is doped into the substrate to divide the substrate into a P type impurity region and an N type impurity region. Active patterns having a first pitch are formed in the P type and N type impurity regions. Gate patterns having a second pitch are formed on the active patterns in a direction substantially perpendicular to the active patterns. Other embodiments are described and claimed.
US08193045B2 Manufacturing method of thin film transistor using oxide semiconductor
A manufacturing method of a thin film transistor having at least a gate electrode, a gate insulation film, an oxide semiconductor layer, a first insulation film, a source electrode, a drain electrode, and a second insulation film on a substrate, including: forming the gate electrode on the substrate; forming the gate insulation film on the gate electrode; forming a semiconductor layer including amorphous oxide on the gate insulation film; patterning the gate insulation film; patterning the oxide semiconductor layer; reducing the oxide semiconductor layer in resistance by forming the first insulation film on the oxide semiconductor layer in the atmosphere not including an oxidized gas; patterning the first insulation film and forming a contact hole between the source electrode and the drain electrode and the oxide semiconductor layer; forming a source electrode layer and a drain electrode layer in the oxide semiconductor layer through the contact hole; forming the source electrode and the drain electrode through the contact hole and allowing the first insulation film to be exposed; patterning the exposed first insulation film and allowing a channel region of the oxide semiconductor layer to be exposed; and increasing the channel region in resistance by forming the second insulation film on the surface including the channel region of the oxide semiconductor layer in the atmosphere including an oxidized gas.
US08193032B2 Ultrathin spacer formation for carbon-based FET
A method for formation of a carbon-based field effect transistor (FET) includes depositing a first dielectric layer on a carbon layer located on a substrate; forming a gate electrode on the first dielectric layer; etching an exposed portion of the first dielectric layer to expose a portion of the carbon layer; depositing a second dielectric layer over the gate electrode to form a spacer, wherein the second dielectric layer is deposited by atomic layer deposition (ALD), and wherein the second dielectric layer does not form on the exposed portion of the carbon layer; forming source and drain contacts on the carbon layer and forming a gate contact on the gate electrode to form the carbon-based FET.
US08193027B2 Method of making a multicomponent film
Described herein is a method and liquid-based precursor composition for depositing a multicomponent film. In one embodiment, the method and compositions described herein are used to deposit Germanium Tellurium (GeTe), Antimony Tellurium (SbTe), Antimony Germanium (SbGe), Germanium Antimony Tellurium (GST), Indium Antimony Tellurium (IST), Silver Indium Antimony Tellurium (AIST), Cadmium Telluride (CdTe), Cadmium Selenide (CdSe), Zinc Telluride (ZnTe), Zinc Selenide (ZnSe), Copper indium gallium selenide (CIGS) films or other tellurium and selenium based metal compounds for phase change memory and photovoltaic devices.
US08193025B2 Photomask, image sensor, and method of manufacturing the image sensor
Provided are a photomask, an image sensor, and a method of manufacturing the image sensor. The image sensor can include photodiode structures, color filters, a planarization layer, and microlenses. The photodiode structures can be disposed on a semiconductor substrate according to unit pixel. The color filters can be disposed on the semiconductor substrate in a matrix arrangement above the photodiode structures. The planarization layer can cover the entire semiconductor substrate and includes cavities in regions of the planarization layer corresponding to boundaries between the color filters. The cavities may be arranged at boundaries between unit pixels. The microlenses can be disposed on the planarization layer such that portions of the microlenses are arranged in the cavities of the planarization layer.
US08193021B2 Nitride semiconductor and method for manufacturing same
A nitride semiconductor includes: a substrate having a major surface including a first crystal polarity surface and a second crystal polarity surface different from the first crystal polarity surface; and a single polarity layer provided above the major surface and having a single crystal polarity.
US08193017B2 Organic light emitting display device and method of manufacturing the same
An organic light emitting display device includes a substrate, a plurality of pixels on the substrate having a first region configured to emit light and a second region configured to transmit external light, a plurality of pixel circuit units, a plurality of first electrodes, a first organic layer on the plurality of first electrodes, a second organic layer on the first organic layer, the second organic layer including an emission layer, a third organic layer on the second organic layer, the third organic layer being positioned in the first region and outside a central portion of the second region, and a second electrode having a first portion only on the third organic layer.
US08193012B2 LED module fabrication method
A method of fabricating a LED module by: bonding one or multiple LED chips and multiple conducting terminals to a circuit substrate, and then molding a packing cup on the circuit substrate over by over molding for enabling the LED chip(s) and the conducting terminals to be exposed to the outside of the packing cup, and then molding a lens on the packing cup and the LED chip(s) by over-molding. By means of directly molding the lens on the packing cup and the LED chip(s), no any gap is left in the lens, avoiding deflection, total reflection or light attenuation and enhancing luminous brightness and assuring uniform distribution of output light.
US08193009B2 Apparatus and methods for packaging electronic devices for optical testing
Apparatus and methods are provided for packaging IC (integrated circuit) chips to enable both optical access to the back side of an IC chip and electrical access to the front side of the IC chip.
US08193007B1 Etch process control using optical metrology and sensor devices
Provided is a method and system for controlling a fabrication cluster for processing of a substrate in an etch process, the fabrication cluster having equipment settings and process parameters. A correlation of etch stage measurements to actual etch stage data is developed, the etch stage measurements comprising measurements using two or more optical metrology devices and an etch sensor device. An etch stage value is extracted using the developed correlation and the etch stage measurement. If the etch stage measurement objectives are not met, the metrology devices are modified, a different etch sensor device is selected, the etch stage measurements are enhanced, and/or the correlation algorithm is refined. The steps are iterated until the etch stage measurement objectives are met. The extracted etch stage value is used to adjust an equipment setting and/or process parameter of the fabrication cluster.
US08193004B2 Method for forming ferroelectric spontaneous polarization reversal
A method for forming a ferroelectric spontaneous polarization reversal in a desired region of a ferroelectric substrate, wherein thickness of the ferroelectric substrate in the desired region A of the ferroelectric substrate is thinner than in a region B outside the desired region of the substrate, comprising the step of applying a given voltage into the ferroelectric substrate by a liquid electrode method to thereby form a ferroelectric spontaneous polarization reversal in the desired region of the ferroelectric substrate.
US08192999B2 Method for the identification of macromolecule targets of analytes
There is provided a method for the identification of macromolecule targets of analytes such as drugs in biological samples comprising complex mixtures of macromolecules. A biological sample is contacted with one or more analyte and the mixture is resolved such that the analyte and its target are co-eluted and analyzed to identify analyte-target complexes.
US08192988B2 Methods for increasing potency of adult mesenchymal stem cells
Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage.
US08192987B2 Human dental follicle stem cells and methods for obtaining
A stem cell which is obtainable from the non-embryonic tissue isolated from the dental follicle of tooth or wisdom tooth which are able to differentiate into a periodontal ligament like membrane structure.
US08192986B2 Compositions and methods for treatment of protein misfolding diseases
Disclosed are methods for identifying compounds that modulate huntingtin mediated impairment of protein degradation pathways. Compounds identified by such screens can be used as candidate drugs for the treatment of prevention of polyglutamine diseases such as Huntington's Disease.
US08192980B2 Microreactor, process for the preparation thereof, and process for carrying out a biochemical or biological reaction
A microreactor is shown having an inlet or feed channel, an inlet or feed zone for a flow of fluid, a reaction zone, an outlet zone and an outlet or evacuation channel, the zones and channels being in fluid communication, and at least one compound such as an enzyme capable of producing a biological or biochemical reaction with at least one constituent of the flow of fluid, the compound being attached to the surfaces of the inlet zone, reaction zone, and outlet zone.
US08192973B2 Detection of mutations in a gene associated with resistance to viral infection, OAS1
A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided.
US08192972B2 Crystal structure of human JAK3 kinase domain complex and binding pockets thereof
The present invention relates to human Janus Kinase 3 (JAK3) and JAK3-like binding pockets. The present invention provides a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen for and design compounds, including inhibitory compounds, that bind to JAK3 protein or JAK3 protein homologues, or complexes thereof. The invention also relates to crystallizable compositions and crystals comprising JAK3 kinase domain and JAK3 kinase domain complexed with AMP-PNP.
US08192968B2 Method for the production of a fermentation product from a pretreated lignocellulosic feedstock
A method for obtaining a fermentation product from a sugar hydrolysate obtained from a feedstock containing hemicellulose, by (i) removing suspended fiber solids from said sugar hydrolysate to obtain a clarified sugar solution; (ii) fermenting xylose in the clarified sugar solution in a fermentation reaction with yeast to produce a fermentation broth comprising the fermentation product; (iii) separating the yeast from the fermentation broth to produce a yeast slurry; (vi) treating the yeast slurry thus obtained with an oxidant to kill microbial contaminants, thereby an oxidant-treated yeast slurry; (v) re-introducing at least a portion of the oxidant-treated yeast back to step (ii) to increase the concentration of yeast in said fermentation reaction; and (vi) recovering the fermentation product.
US08192967B2 Reductase, gene thereof and method of using the same
The present invention relates to a protein which can asymmetrically reduce an ortho-substituted phenylglyoxalic acid compound to produce an amide or ester compound of corresponding optically-active ortho-substituted mandelic acid compound with a good optical yield, a DNA encoding the protein, a process for producing the protein from the DNA, and a process for asymmetrically reducing an ortho-substituted phenylglyoxalic acid compound to produce a corresponding optically-active ortho-substituted mandelic acid compound.
US08192966B2 Biochemical concentrator and drug discovery
A novel label-free sensitive detection method by employing a novel sensitive charge sensor is provided. Dissociation constant information is provided by a simple measurement of the dissociation of the target molecule form the target's receptor. The later process is affected by a novel system and its configuration as described herein. Basic objectives are to provide a drug discovery and characterization system that is an improvement over the current state of the art, low cost, highly sensitive, accurate, fast and easy to use. This invention involves both a physical system and a methodology.
US08192965B2 Producing Itaconic acid in yeast using glycerol as the substrate
Method for producing itaconic acid in yeast cells using glycerol as the substrate. The yeast cells express cis-aconitic acid decarboxylase and optionally, citrate synthase and/or aconitase at high levels.
US08192961B2 System and methods for nucleic acid sequencing of single molecules by polymerase synthesis
This invention relates to improved methods for sequencing and genotyping nucleic acid in a single molecule configuration. The method involves single molecule detection of fluorescent labeled PPi moieties released from NTPs as a polymerase extension product is created.
US08192960B2 One component and two component DNA Pol III replicases and uses thereof
The invention provides one-component and two-component DNA polymerases, as well as kits comprising the same, and methods of using the same for nucleic amplification and nucleic acid sequencing.
US08192958B2 Nucleic acid isolation using polidocanol and derivatives
This invention relates to a composition comprising a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof. The invention is further related to uses of this composition and to a kit comprising the composition according to the invention. The invention is further related to a method for the detection of a nucleic acid in a biological sample comprising the steps of incubating the biological sample in the presence of a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof, optionally isolating the nucleic acid, optionally amplifying the nucleic acid, and detecting the nucleic acid. The invention is further related to a method for the purification of a nucleic acid in a biological sample comprising the steps of incubating the biological sample in the presence of a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof and isolating the nucleic acid thereby purifying the nucleic acid.
US08192957B2 Fibrillation-resistant insulin and insulin analogues
A fibrillation-resistant insulin analogue may be a single-chain insulin analogue or a physiologically acceptable salt thereof, containing an insulin A chain sequence or an analogue thereof and an insulin B chain sequence or an analogue thereof connected by a polypeptide of 4-10 amino acids. The fibrillation-resistant insulin analogue preferably displays less than 1 percent fibrillation with incubation at 37° C. for at least 21 days. A single-chain insulin analogue displays greater in vitro insulin receptor binding than normal insulin while displaying less than or equal binding to IGFR than normal insulin. The fibrillation-resistant insulin may be used to treat a patient using an implantable or external insulin pump, due to its greater fibrillation resistance.
US08192956B2 Hybrid genes and enzymes of glucanase and dextransucrase and processes for preparing isomalto-oligosaccharides or dextran using the same
Disclosed are hybrid genes of glucanase and dextransucrase, recombinant vectors comprising said hybrid genes, microorganisms which are transformed with said recombinant vectors, hybrid enzymes which are expressed from said hybrid genes, and processes for preparing isomalto-oligosaccharides or dextran using said microorganisms or enzymes. Expensive isomalto-oligosaccharides and low molecular weight dextran for clinical use can be produced simply and effectively from cheap substrate-sucrose, using a single bacterial strain or enzyme.
US08192946B2 Assays for detecting pregnancy-associated glycoproteins
Disclosed are methods and compositions for detecting pregnancy in an animal by means of assaying peptidase activity of one or more Pregnancy Associated Glycoproteins (PAGs). In certain aspects, methods also comprising use of an antibody that binds immunologically to a PAG that displays proteolytic activity are provided. Substrates of proteolytic PAGs are also provided, as are kits, and methods of use. Further, methods of purifying PAGs based on their proteolytic activity are also provided.
US08192942B2 Affinity separation by partition enhancing material conjugated biomolecules in aqueous two-phase extraction system
The present invention relates to a method for separating a material that has affinity to an antibody by using a protein-antibody conjugate with modified partition characteristics, more precisely a method for affinity separation to separate a material specifically binds to an antibody, in which an antibody is conjugated to a protein to modify partition characteristics of the protein-antibody conjugate. The method of the present invention can be effectively and widely used as a safe and efficient separation method for biomolecules since it takes advantages of safe aqueous two-phase extraction system and high selective molecular specific conjugation.
US08192930B2 Method for sequencing a polynucleotide template
The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.
US08192927B2 Human bind molecules capable of neutralizing influenza virus h5n1 and uses thereof
The present invention relates to binding molecules such as human monoclonal antibodies that bind to influenza virus H5N1 and have neutralizing activity against influenza virus H5N1. The disclosure provides nucleic acid molecules encoding the antibodies, their sequences and compositions comprising the antibodies and methods of identifying or producing the antibodies. The antibodies can be used in the diagnosis, prophylaxis and/or treatment of an influenza virus H5N1 infection. In a preferred embodiment, the antibodies provide cross-subtype protection in vivo, such that infections with H5, H2, H6, H9 and H1-based influenza subtypes can be prevented and/or treated.
US08192922B2 Method of optical fabrication of three-dimensional polymeric structures with out of plane profile control
A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.
US08192910B2 Image forming method, image forming apparatus and process cartridge
An image forming method, including charging the surface of an electrostatic latent image bearer by a charger; irradiating the surface of the electrostatic latent image bearer to form an electrostatic latent image thereon; developing the same with a toner to form a toner image; transferring the toner image onto a recording medium; and fixing the toner image thereon, wherein the charger is a charging roller contacting the electrostatic latent image bearer to charge the same, having a ten-point surface roughness of 5 to 30, and the toner includes a binder resin, a colorant, a release agent and an external additive including a composite oxide including titanium oxide in an amount of 80 to 95% by weight and silicon oxide, having a core-shell structure formed of a core including the titanium oxide and a shell including the silicon oxide and has a BET specific surface area of 50 to 100 m2/g.
US08192907B2 Toner
A toner including toner particles containing at least a binder resin and a colorant. The binder resin is a vinyl-based resin. The toner contains a THF insoluble matter in a quantity of 0.0 mass % or more to less than 16.0 mass %. The toner has a main peak in a molecular weight domain Dr1 ranging from 5,000 to 80,000 in measurement of THF soluble matter of the toner with a gel permeation chromatogram (GPC)-differential refractive index detector (RI), and the toner has a main peak in a molecular weight domain Dm1 ranging from 10,000 to 120,000 and at least one peak in a molecular weight domain Dm2 ranging from 300,000 to 7,000,000 in the GPC-RI measurement in measurement with a GPC-multi-angle laser light scattering detector (MALLS).
US08192905B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge
An electrophotographic photoconductor contains a photosensitive layer and a conductive substrate, wherein the photosensitive layer is disposed on the conductive substrate, and the photosensitive layer is a single layer containing a charge generating material, an electron transporting material expressed by the General Formula (1) and a hole transporting material expressed by the General Formula (2):
US08192904B2 Electrophotographic photoconductor, and image forming apparatus and process cartridge using the same
An electrophotographic photoconductor including: an outermost layer, wherein the outermost layer comprises an amino group-containing acryl-modified polyorganosiloxane, wherein the amino group-containing acryl-modified polyorganosiloxane is a copolymer in which a polyorganosiloxane represented by the following structural formula (1) and an acrylic monomer are graft-polymerized
US08192899B2 Pellicle for photolithography
There is provided a pellicle for photolithography having a plurality of air vents formed in a pellicle frame for photolithography and having the air vents covered with a dustproof filter in which the air vents in the frame are counterbored and a counterbored wall surface of the air vents is tapered.
US08192898B2 Composition for fluorine-containing volume holographic data recording material and fluorine-containing volume holographic data recording media made of same
The present invention provides a fluorine-containing volume holographic data recording material making it unnecessary to provide a step of eliminating a specific solvent even in the case of a thick film, and having high hologram performance and good dynamic range. There is provided a composition comprising a base polymer (a), a liquid monomer (b) and a photo-initiator (c), wherein the base polymer (a) is an amorphous polymer comprising a fluorine-containing monomer as a structural unit and having a fluorine content of 26 to 80% by mass, the liquid monomer (b) comprises at least one liquid monomer (b1) initiating polymerization by means of activated species generated from the photo-initiator (c), the photo-initiator (c) is a compound causing the liquid monomer (b1) to initiate polymerization by exposure to light having excellent coherence and, and a refractive index of the liquid monomer (b) is higher than an average refractive index of a mixture of the base polymer (a) and the photo-initiator (c).
US08192896B2 Membrane-membrane reinforcing member assembly, membrane-catalyst layer assembly, membrane-electrode assembly, polymer electrolyte fuel cell, and method for manufacturing membrane-electrode assembly
A membrane-membrane reinforcing member assembly includes: a polymer electrolyte membrane (1); one or more membrane-like first membrane reinforcing members (10) disposed on a main surface (F10) of the polymer electrolyte membrane (1) so as to extend along a peripheral edge of the polymer electrolyte membrane (1) as a whole; and one or more membrane-like second membrane reinforcing members (11) disposed on the first membrane reinforcing members (10) so as to extend along the peripheral edge of the polymer electrolyte membrane (1) as a whole and disposed such that an inner edge of the second membrane reinforcing member (11) and an inner edge of the first membrane reinforcing member (10) do not coincide with each other.
US08192894B2 Plate-laminating type fuel cell
A fuel cell is formed by stacking an electrolyte electrode assembly and a pair of separators alternately. Each of the separators includes first to third plates. A first cylindrical portion provided at a first small diameter end portion of one separator is inserted into a fuel gas supply passage of the other separator. The first cylindrical portion is subjected to a crimping process such that a joint portion as a predetermined overlapping portion is formed integrally with the one separator and the other separator.
US08192890B2 Fuel cell air exchange apparatus
A fuel cell air exchanger is provided. The fuel cell air exchanger includes a platform having at least one throughput opening and at least one holding post, where the holding post fixedly holds a fuel cell offset from the platform and proximal to the opening, where the opening can have many shapes. The fuel cell air exchanger provides an unimpeded air exchange through the openings to the fuel cell and can be flexible, semi-flexible or rigid. The fuel cell air exchanger can hold an array of fuel cells and fuel cell electronics. A chimney feature provides enhanced airflow when the air exchanger is disposed in a vertical position.
US08192889B2 Proton exchange membrane fuel cell stack and fuel cell stack module
A proton exchange membrane fuel cell stack and novel proton exchange membrane fuel cell module are disclosed and wherein the proton exchange membrane fuel cell stack includes a plurality of repeating, serially electrically coupled fuel cell stack modules, and which are sealably mounted together by a compressive force of less than about 60 pounds per square inch.
US08192888B2 Two layer electrolyte supported fuel cell stack
Self-supporting thin film membranes of ceramic materials and related electrochemical cells and cell stacks. The membrane structure is divided into a plurality of self-supporting thin membrane regions by a network of thicker integrated support ribs. The membrane structure may be prepared by laminating a thin electrolyte layer with a thicker ceramic layer that forms a network of support ribs.
US08192882B2 Fuel cell and aircraft hydraulic system having a common cooling circuit
A system utilizing synergetic potentials at different systems such as of a fuel cell system and of an aircraft hydraulic system, through coupling them via a common cooling circuit system.
US08192881B2 Control method for cold fuel cell system operation
A method of operating a fuel cell system comprising a fuel cell and a compressor that provides air to the fuel cell. The method comprises sensing a temperature indicative of the temperature of a fuel cell, providing a restriction in an air flow path to the fuel cell when the sensed temperature is below a threshold, and increasing the speed of the compressor to provide a desired air flow to the fuel cell. In at least some implementations, increasing the speed of the compressor increases the power drawn from the fuel cell to power the compressor and helps to increase the heat of the fuel cell. The increased speed of the compressor can also result in warmer air flow from the compressor that can further increase the temperature of the system components.
US08192879B2 Method for maximum net power calculation for fuel cell system based on online polarization curve estimation
An algorithm for determining the maximum net power available from a fuel cell stack as the stack degrades over time using an online adaptive estimation of a polarization curve of the stack. The algorithm separates the current density range of the stack into sample regions, and selects a first sample region from the far left of the estimated polarization curve. The algorithm then calculates the cell voltage for that current density sample region, and determines whether the calculated cell voltage is less than or equal to a predetermined cell voltage limit. If the calculated cell voltage is not less than the cell voltage limit, then the algorithm selects the next sample region along the polarization curve. When the calculated cell voltage does reach the cell voltage limit, then the algorithm uses that current density for the sample region being analyzed to calculate the maximum power of the fuel cell stack.
US08192871B2 Lithium secondary battery and production method of the same
To provide a lithium secondary battery which suppresses a decrease in the charge and discharge efficiency during a battery storage test and which is excellent in maintaining the battery capacity after the storage test. There are disclosed a nonaqueous lithium battery, comprising: a positive electrode active material comprising a lithium-containing oxide capable of inserting and detaching lithium ions; a negative electrode active material comprising a carbon material capable of inserting and detaching lithium ions; and an electrolytic solution containing a lithium ion, wherein the surface of the negative electrode active material after initializing charging is coated with a compound derived from vinylene carbonate, and wherein a weight power density of the lithium battery is no less than 100 Wh/kg, and a method of producing a nonaqueous lithium battery comprising a step of sealing a positive electrode active material, a negative electrode active material, and a nonaqueous electrolytic solution using a sealed container, wherein a predetermined amount of vinylene carbonate is added into the nonaqueous electrolytic solution, and the initializing charging is carried out to form a coating on the surface of the negative electrode active material, the coating being derived from the vinylene carbonate.
US08192870B2 Supercapacitor and battery electrode containing thermally exfoliated graphite oxide
A supercapacitor or battery electrode containing a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g.
US08192866B2 Tin nanoparticles and methodology for making same
A method of preparing tin (Sn) nanoparticles based on a bottom-up approach is provided. The method includes combining a first solution comprising Sn ions with a second solution comprising a reducing agent. After the combination, the Sn ions and the reducing agent undergo a reaction in which at least some of the Sn ions are reduced to Sn nanoparticles. The first solution comprises a tin salt dissolved in a solvent; the second solution comprises an alkali metal and naphthalene dissolved in a solvent; and the combined solution further comprises a capping agent that moderates a growth of aggregates of the Sn nanoparticles.
US08192864B2 Battery, examination method and manufacturing method for negative electrode thereof, and examination apparatus and manufacturing apparatus for negative electrode thereof
In a method for examining a negative electrode of a battery, a total thickness of a current collector and an active material layer is measured. Then, in order to estimate a composition of the active material layer, the total resistivity of the current collector and the active material layer is measured.
US08192859B2 Secondary battery, battery pack and car
A secondary battery includes a positive electrode, a negative electrode containing a metal compound having a lithium ion absorption potential of 0.2V (vs.Li/Li+) or more, a separator and a nonaqueous electrolyte. The separator is provided between the positive electrode and the negative electrode. The separator comprises cellulose fibers and pores having a specific surface area of 5 to 15 m2/g. The separator has a porosity of 55 to 80%, and a pore diameter distribution having a first peak in a pore diameter range of 0.2 μm (inclusive) to 2 μm (exclusive) and a second peak in a pore diameter range of 2 to 30 μm.
US08192857B2 Battery assembly and method of forming the same
A battery assembly includes a first cell and a second cell adjacent the first cell. A first insulator and a second insulator extend over and encapsulate first electrode and second electrode. A shell extends over the first and second insulators thereby encapsulating the first and second insulators. A mechanical connection is defined between the first insulator of the fist cell and the second insulator of the second cell.
US08192855B2 Protective circuit module and secondary battery having the same
A secondary battery having a bare cell and a protective circuit module disposed over the bare cell and electrically connected to the bare cell via a first lead plate, in which the first lead plate includes a first plate, a second plate connected to the first plate, and a third plate arranged opposite to the first plate and connected to the second plate.
US08192854B2 Microbial fuel cell treatment of ethanol fermentation process water
The present invention relates to a method for removing inhibitor compounds from a cellulosic biomass-to-ethanol process which includes a pretreatment step of raw cellulosic biomass material and the production of fermentation process water after production and removal of ethanol from a fermentation step, the method comprising contacting said fermentation process water with an anode of a microbial fuel cell, said anode containing microbes thereon which oxidatively degrade one or more of said inhibitor compounds while producing electrical energy or hydrogen from said oxidative degradation, and wherein said anode is in electrical communication with a cathode, and a porous material (such as a porous or cation-permeable membrane) separates said anode and cathode.
US08192852B2 Ceramic insulator and methods of use and manufacture thereof
One embodiment of the present disclosure is directed to an insulator comprising a ceramic composition, wherein the ceramic composition comprises about 25-60% SiO2; 15-35% R2O3, wherein the R2O3 is 3-15% B2O3 and 5-25% Al2O3; 4-25% MgO+0-7% Li2O, wherein the total of MgO+Li2O is between about 6-25%; 2-20% R2O, wherein the R2O is 0-15% Na2O, 0-15% K2O, 0-15% Rb2O; 0-15% Rb2O; 0-20% Cs2O; and 4-20% F; crystalline grains, wherein the crystalline grains are substantially oriented to extend in a first direction to provide improved insulating properties in a direction perpendicular to the first direction, wherein the first direction is circumferential and the direction perpendicular to the first direction is radial; and a first zone and a second zone, wherein the first zone is in compression and the second zone is in tension.
US08192846B2 Composition and manufacturing process of a decorative surface covering
The present invention relates to a decorative surface covering obtainable by a vulcanisable composition, said composition comprising a first polymer component consisting of styrene butadiene styrene block copolymer (SBS); a second polymer component selected from the group consisting of a random or partially random copolymer of butadiene and styrene (SBR), and nitrile butadiene rubber (NBR); a third polymer component consisting of a high styrene content styrene butadiene copolymer (HSR), a filler, a vulcanisation system and additives selected from the group consisting of processing aids, stabilizers, pigments and compatibilizers.
US08192843B2 Polymers and polymer coatings
The invention provides polymers, methods of preparing polymers, and compositions that include polymers, wherein said polymers include a plurality of two-carbon repeating units in a polymer chain, wherein one or more of the two-carbon repeating units of the polymer chain have a substituent that is covalently bonded to a semifluorinated alkyl ethoxy moiety, and the semifluorinated alkyl ethoxy moiety is attached to the polymer chain substituent through an ester, amide, ketone, carbamate, amine, or other suitable linking group. The polymers can be used to provide antifouling coatings.
US08192838B2 Controlled release materials
The invention relates to polymers whose water solubility may be triggered by changes in pH, salt concentration, concentration of surfactant or a combination of both. The polymer is a copolymer or terpolymer containing from 2 to 60 mole percent of an amine functionality that has been neutralized with a fixed acid. Specifically films formed from these polymers will be insoluble at a higher pH, but will become soluble at a lower pH. The polymers are also insoluble at a higher salt concentration, but become soluble at a lower salt concentration. The polymers can be used to coat or encapsulate active ingredients, that are released based on changes in the environment, such as in the rinse cycle of a dishwasher or laundry washing machine.
US08192831B2 Articles for high temperature service and methods for their manufacture
Articles coated via a plasma spray process, and methods for making such articles, are presented. For example, one embodiment is an article comprising a substrate comprising a top surface and a channel disposed in the substrate. The channel is defined by an internal channel surface disposed beneath the top surface and having a terminal end at an orifice at the top surface. A coating is disposed on the top surface and on at least a portion of the internal channel surface. A coating thickness at any point on the internal channel surface is less than a nominal coating thickness on the top surface, and the coating comprises a plurality of at least partially melted and solidified particles.
US08192829B2 Cast photoluminescent devices and photoluminescent inserts for substrates
A non-powered path marking system comprises a substrate defining a cavity. A photoluminescent insert comprises a first resinous layer that is cast with photoluminescent particles suspended therein. Adhesive attaches the photoluminescent insert inside of the cavity. A marking device comprises a photoluminescent insert comprising N cast resinous layers, wherein N is an integer greater than or equal to one. A first one of the N cast resinous layers includes photoluminescent particles suspended therein. A fastener includes a first portion cast in the photoluminescent insert and a second portion extending outside of the photoluminescent insert.
US08192827B2 Reinforced extrusion and method for making same
A reinforced extrusion for attachment to a motor vehicle component edge or flange. The reinforced extrusion includes a reinforcement core having at least one flexible wire and at least one threaded cord. A thermoplastic overmold is formed on at least one side of the reinforcement core and at least partly fills any gaps formed in the reinforcement core. An extruded layer is selectively formed around the thermoplastic overmold and reinforcement core and has a flange extending flange portion extending from a channel portion for engaging a motor vehicle component. The thermoplastic overmold helps prevent the reinforcement core from showing through to any visible show surface of the reinforced extrusion.
US08192825B2 Low melt plastic fastener
A low-melt plastic fastener. According to one embodiment, the low-melt plastic fastener is shaped to include a flexible filament having a first cross-bar at a first end, and a second cross-bar at a second end. The filament, the first cross-bar, and the second cross-bar may be formed from the same material and may be molded as a unitary structure. Preferably, the fastener is molded as part of a length of continuously connected ladder stock. The plastic fastener is preferably made from a formulation consisting of about 60-99%, by weight, of a low-melt polyurethane and 1-40%, by weight, of a styrene acrylonitrile. The formulation is selected so that the filament melts when heated for about 10 minutes at 130-180° C.
US08192810B2 Method for using static electricity reducing/removing instrument and static electricity reducing/removing device
A glass container storing unit in which the bottom section of a conical first glass container is stored is supported on one base of a cylindrical motor storing unit in which a motor stored, with a rotation axis. A second glass container in the shape of a Welsh onion flower is attached to the other base of the motor storing unit. Negatively charged metallic silicon is sealed in the first glass container and second glass container. The pointed section of the first glass container is pressed against a human body by rotating the first glass container with the rotation axis.
US08192806B1 Plasma particle extraction process for PECVD
A plasma-enhanced chemical vapor deposition (PECVD) process including plasma particle extraction is described. Charged particles suspended in discharge volume are moved together with a plasma and can then be flushed away. The particle extraction process reduces unwanted particles on the wafer after deposition and reduces total process time. In some embodiments, the process can involve powering an electrode in the process chamber located away from the wafer. This electrode can be powered up as the main deposition electrode is powered down.
US08192805B2 Method to improve electrical leakage performance and to minimize electromigration in semiconductor devices
Embodiments of methods for improving electrical leakage performance and minimizing electromigration in semiconductor devices are generally described herein. Other embodiments may be described and claimed.
US08192799B2 Spray nozzle assembly for gas dynamic cold spray and method of coating a substrate with a high temperature coating
The invention relates to an improved design for a spray gun and application system for cold gas dynamic spraying of a metal, alloy, polymer, or mechanical mixtures thereof. The gun includes a rear housing comprising a powder inlet and a gas inlet, a front housing removably affixed to the rear housing and comprising an mixing cavity therein for mixing of the powder and gas and an exit therefrom, a nozzle holder having a bore disposed therethrough and removably affixed to the front housing, and a polymeric nozzle positioned within the nozzle holder, an interior taper of the nozzle holder bore complementing an exterior taper of the nozzle. The nozzle having an initially converging, subsequently diverging centrally disposed bore therein adapted to receive the mixed powder and gas from the mixing chamber and the nozzle holder including a cooling jacket which is thermally coupled to the nozzle adjacent the nozzle inlet and mechanically coupled downstream of the nozzle inlet.
US08192797B2 Fabric treatment for reinforced elastomeric articles
A fabric or cord is treated with an elastomeric compound comprises 20-80 parts per hundred cross-linkable materials of liquid elastomer. The liquid elastomer has a complex dynamic viscosity less than 5 McP (5,000 N*s/m2) at a temperature between 20° C. and the maximum flow temperature TF, and the elastomeric compound the elastomeric material, prior to cure, has a complex dynamic viscosity of less than 5 McP (5,000 N*s/m2) for at least 2 minutes at a maximum flow temperature TF. The coated fabric and cord materials are useful as facing fabrics for power transmission products.
US08192794B2 Massively parallel lithography with two-dimensional pen arrays
Massive parallel printing of structures and nanostructures, including lipids, at high speed with high resolution and high quality using two dimensional arrays comprising cantilevers and tip-based transfer of material to a surface. The invention provides a nanolithographic method comprising (1) providing a two-dimensional array of a plurality of cantilevers, wherein the array comprises a plurality of base rows, each base row comprising a plurality of cantilevers extending from the base row, wherein each of the cantilevers comprising tips at the cantilever end away from the base row; wherein the two dimensional array has a support; (2) providing a patterning composition, wherein the composition comprises one or more lipids; (3) providing a substrate; (4) coating the tips of the cantilevers with the patterning composition; and (5) depositing at least some of the patterning composition from the tips to the substrate surface.
US08192780B2 Dairy product and process
Processed cheese is prepared in a process where the ingredients include at least 0.5% non-denatured whey protein concentrate and at least 0.5% denatured whey protein concentrate. The method can be used to prepared processed cheese with improved melting characteristics.
US08192776B2 Chewable animal toy
A chewable animal toy having an edible core and a tearable outer shell molded around the edible core such that a portion of the edible core protrudes from the outer shell is provided. Further provided is a mold unit for making the chewable animal toy having a first mold half including a first mold cavity and a second mold half having a second mold cavity. The second mold half is engageable with the first mold half such that the first and second mold cavities cooperatively define an outer shell mold cavity. A first pocket is defined between the first and second mold halves that is adapted to receive a first protruding portion of the edible core. A first shut off defined within the first pocket is adapted to surround the first protruding portion of the edible core such that it is substantially isolated from the outer shell mold cavity.
US08192775B2 Crystallization of polyol compositions, crystalline polyol composition product and use thereof
The present invention relates to microcrystallized polyol comprising at least two polyols, wherein said polyols are selected from the group consisting of maltitol, xylitol and lactitol and wherein said composition contains at least 35% by weight of each of at least two of said polyols microcrystallized together into a solid microcrystalline product. The present invention also relates to a process for the microcrystallization of polyols into a polyol composition. The microcrystallized polyol composition can be used in confectionery, foodstuffs, oral hygiene products and pharmaceuticals and in dietetic products.
US08192774B2 Oil extraction
This invention features a method of producing a triglyceride solution. The method includes contacting a liquid fatty acid alkyl ester and a substance containing triglyceride so that the triglyceride is dissolved into the fatty acid alkyl ester to form a triglyceride solution.
US08192773B2 Carotenoid-based pigmenter
A stabilized carotenoid-based pigmenter free of synthetic antioxidants for the addition to animal feed to add color to tissues of animals fed the animal feed. The carotenoid-based pigmenter contains free-form carotenoids obtained from natural sources through a saponification reaction. A natural antioxidant, such as grape seed extracts, green tea extracts, clove bud oil, clove leaf oil, Vitamin C, cinnamon leaf oil, oleoresin turmeric, tocopherol, tocotrienol, rosemary extracts and gallic acid or salts thereof combined with a diluent, preferably glycerol or a glycerol-like substance, is added to the pigmenter after the saponification reaction.
US08192767B2 Antioxidant compositions comprising extracts of myrtle and rosemary
The invention relates to a composition based on extracts of myrtle and rosemary which has been found to synergistically increase the protection of cells against pathophysiological conditions characterised and partly caused by overproduction of free radicals and to counteract the oxidative stress caused by excessive production of said free radicals, as well as for preventing and/or treating related pathologies, including apoptosis.
US08192759B2 Matrix made of polyester polymers entangled with hyaluronic polymers useful for supporting tissue repair
The present application discloses matrix compositions to support the repair of tissue defects such as an osteochondral injury. A matrix described herein comprises a polyester polymer entangled with a polysaccharide polymer. Also disclosed are methods of preparing a matrix, and methods of using a matrix in the repair of tissue. In certain configurations, a matrix can comprise a polyester cross-linked with a polysaccharide, which can be an oxidized polysaccharide. In some configurations, a matrix can further comprise one or more additional components, such as a growth factor.
US08192758B2 Ion binding compositions
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.
US08192753B2 pH-sensitive cationic lipids, and liposomes and nanocapsules containing the same
The invention suggests a pH-sensitive cationic lipid with a pKa value between 3.5 and 8, according to the general formula cation-spacer-Y-spacer-X-lipid, wherein Y and X represent linking groups. Furthermore, liposomes are described, which liposomes include said optionally cationic lipids.
US08192752B2 Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same
A medical article comprising an implantable substrate having a coating is disclosed, the coating comprising a biologically erodable polymer having the glass transition temperature below about −50° C. The biologically erodable polymer can be blended with a polymeric additive which either has the glass transition temperature of about −50° C. or higher, or a degree of crystallinity greater than that of the first polymer.
US08192750B2 Pharmaceutical composition for the treatment of otomycosis
Disclosed is a composition comprising betamethasone, griseofulvin and tea tree oil, for use in the treatment of ear fungal infections, particularly otomycosis, particularly infections caused by Aspergillus niger or Candida albicans. The composition may be in the form of ointment, cream, gel or liquid, e.g. ear drops.
US08192747B2 Live attenuated rotavirus vaccine for oral administration
This invention provides liquid rotavirus formulations that are suitable for oral administration to human infants. In particular, the invention provides pharmaceutical compositions and vaccines, comprising a rotavirus antigen, a sugar and a carboxylate, wherein said formulation has a pH of between pH 5.0 and pH 8.0 and comprises no phosphate or less than 5 mM phosphate. The invention also provides methods of preparing said rotavirus formulations and use thereof in the prevention or treatment or rotavirus associated diseases in humans.
US08192746B2 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition
The present invention provides a multivalent immunogenic composition having 15 distinct polysaccharide-protein conjugates. Each conjugate consists of a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F or 33F) conjugated to a carrier protein, preferably CRM197. The immunogenic composition, preferably formulated as a vaccine on an aluminum -based adjuvant, provides broad coverage against pneumococcal disease, particularly in infants and young children.
US08192744B2 Drug for treating states related to the inhibition of angiogenesis and/or endothelial cell proliferation
Soluble recombinant CD44 hyaluronic acid binding domain (CD44HABD) inhibits angiogenesis in vivo in chick and mouse and thereby inhibits human tumor growth of various origins. The anti-angiogenic effect of CD44-HABD is independent of hyaluronic acid (HA) binding, since non-HA-binding mutants of CD44HABD still maintain anti-angiogenic properties. The invention discloses soluble non glycosylated CD44 recombinant proteins as a novel class of angiogenesis inhibitors based on targeting of vascular cell surface receptor. A method of block of angiogenesis and treatment of human tumors using recombinant CD44 proteins as well as their analogues is disclosed. As a further embodiment of the invention, methods for screening for new drug targets using CD44 recombinant proteins and their analogues are presented.
US08192741B2 Method of treating rheumatoid arthritis with an anti-IL-6R antibody
The present invention provides methods of preventing or treating rheumatoid arthritis using a fully human antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R). The methods of the present invention may include administration of a second therapeutic agent, such as one or more of a non-steroidal anti-inflammatory drug (NSAID), a glucocorticoid, a disease-modifying anti-rheumatic drug (DMARD), or a TNF-alpha antagonist, T-cell blocker, anti-CD20 antibody, an IL-1, JAK or IL-17 antagonist, or any combination thereof.
US08192736B2 Remedy for endometriosis
The present invention provides a therapeutic agent for endometriosis comprising an interleukin-5 antagonist as an active ingredient.
US08192735B2 Method for modulating appetite
Method of modulating appetite and/or body weight in a subject by administering to the subject an effective amount of a MIC-1 modulating agent. The agent is selected from (i) MIC-1 inhibiting agents which decrease the amount of endogenous MIC-1 in the subject, (ii) MIC-1 inhibiting agents which inhibit the activity of endogenous MIC-1 in the subject, (iii) MIC-1 enhancing agents which enhance the amount of endogenous MIC-1 in the subject, and (iv) MIC-1 enhancing agents which enhance the activity of endogenous MIC-1 in the subject.
US08192734B2 Compositions and methods for bone strengthening
The invention relates to methods of increasing bone strength in an animal, preferably a mammal. In one aspect, the methods provided by the invention involve administering to the animal strontium and a phytase enzyme. In another aspect, methods are provided for treating or preventing osteoporosis in a subject, the method comprising administering to said individual a phytase enzyme and strontium. Also encompassed are animal feed compositions comprising a phytase enzyme and supplemental strontium and a dietary supplement composition for administration to a human, the composition comprising a phytase enzyme and supplemental strontium.
US08192732B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof
This invention provides methods for preparing novel mammalian multipotent stem cells (MSCs), compositions thereof, and methods of preparing and administering the cells.
US08192731B2 Thickened cyanoacrylate compositions
The present invention relates to thickened cyanoacrylate compositions, such as those in gel or non-flowable forms. More particularly, the present invention relates to non-flowable cyanoacrylate compositions which can be packaged in a convenient pocket-sized applicator dispenser for use in spreading the cyanoacrylate compositions onto substrates.
US08192726B1 Naturally derived citrate polyesters having liquid and solid domains
The present invention is directed to a series of polymeric citrate esters that have two different molecular weight ester chains, one solid and one liquid, which when combined into a single molecule make a polymer that is solid, but has very unique flow properties. These materials find applications as additives to formulations in personal care products where there is a desire to have a structured film (provided by the solid fatty group) and flow properties, (provided by the liquid fatty group). These compounds by virtue of their unique structure provide outstanding skin feel and outstanding waterproof properties in cosmetic formulations most notable sunscreens.
US08192718B1 Pharmaceutical composition of nanoparticles
The invention relates to a method for treating disorders or diseases of a tight junction comprising delivering a pharmaceutical composition of nanoparticles to the tight junction, wherein the nanoparticles consist of positively charged chitosan, a negatively charged substrate, optionally a zero-charge compound, and at least one bioactive agent for treating said disorders or diseases of the tight junction of an animal subject.
US08192716B2 Sour shift process for the removal of carbon monoxide from a gas stream
Processes for the catalytic conversion of a carbonaceous composition into a gas stream comprising methane are provided, where a sour shift reaction is used to remove carbon monoxide gas stream produced by the gasification process. The incorporation of the sour shift reaction provides an efficient and cost-effective means of eliminating carbon monoxide from the gas stream. In addition, the sour shift reaction also generates additional hydrogen, thus increasing the amount of hydrogen produced from the gasification process.
US08192714B2 Method for manufacturing carbon nanotubes
A method for manufacturing carbon nanotubes of the present invention includes the steps of: preparing at least one metal selected from a group consisting of iron, cobalt and nickel and an organic compound: and forming carbon nanotubes by using the organic compound as a carbon source, wherein the metal and the organic compound are put into a heating vessel having a substance capable of converting electromagnetic energy into heat, and the organic compound is brought into contact with the metal in a state where the inside of the heating vessel is heated at a temperature of 600° C. to 900° C. by applying the electromagnetic energy to the heating vessel so as to form the carbon nanotubes.
US08192706B2 Method and device for purifying the flue gases of a sintering process of ores and/or other material-containing materials in metal production
A method for purifying waste gases of an at least partially burnt solid fuel to reduce pollutants such as SOx and/or HCl and NOx. The waste gas flows into a moving bed reactor from below through a lower and upper layer of an adsorption and/or absorption agent already polluted with NOx, SOx and/or HCl. SOx and/or HCl components are adsorbed from the waste gas into the NOx loaded adsorption and/or absorption agent. Thereafter, the waste gas is mixed with an ammonium-containing compound and flows through an upper horizontal gas inflow and bulk material removal tray of the moving bed reactor into the upper layer of the adsorption and/or absorption agent already polluted with NOx and small quantities of SOx and/or HCl. During the throughflow of the upper layer, NOx components are adsorbed from the waste gas onto the adsorption/absorption agent.
US08192705B2 Methods of treatment of chromite ore processing residue
Methods to reduce hexavalent chromium (Cr(VI)) in chromite processing wastes include one or more of the following steps: contacting the chromite processing wastes with an oxygen scavenger or chemical reducer; permitting the chromite processing wastes to react with the oxygen scavenger or chemical reducer; contacting the chromite processing wastes with ferrous ion; contacting the chromite processing wastes with sulfide ion; and, contacting the chromite processing wastes with ferrous sulfide.
US08192702B2 Sample tubes for use in automated systems and methods of manufacture
One or more embodiments of the invention are directed to sample tubes comprising a cylindrical elongate tube having a gripping section with at least one discontinuity extending radially about the outside surface of the elongate tube. Methods of making sample tubes and their use in sample handlers are also described.
US08192696B2 System and process of biodiesel production
A system and process for continuous production of fatty acid methyl esters (FAME) from the fatty acid triglycerides of waste oil via transesterification in the presence of a reusable sugar-based catalyst. The system and process incorporates re-cycling and re-use of waste by-product streams to result in a near-zero emissions, with a 97% product yield mix consisting of almost pure biodiesel and a very small percentage of impurities including glycerol.
US08192690B2 Methods and devices for polymerization
A method of treating a gas phase fluidized bed reactor and a method of polymerizing olefins in a gas phase fluidized bed reactor in the presence of a catalyst prone to cause sheeting by introducing a chromium-containing compound into the reactor and forming a high molecular weight polymer coating on the walls of the reactor. Furthermore, a device for and method of introducing the chromium-containing compound into the fluidized bed reactor at a plurality of locations in proximity to a lower section of a bed section wall of the fluidized bed reactor, and forming a high molecular weight polymer coating on the bed section wall.
US08192688B2 Trifluid reactor
A thermally diluted exothermic reactor system is comprised of numerous orifices distributed within a combustor by distributed perforated contactor tubes or ducts. The perforated contactors deliver and mix diluent fluid and one or more reactant fluids with an oxidant fluid. Numerous micro-jets about the perforated tubes deliver, mix and control the composition of reactant fluid, oxidant fluid and diluent fluid. The reactor controls one or more of composition profiles, composition ratio profiles and temperature profiles in one or more of the axial direction and one or two transverse directions, reduces temperature gradients and improves power, efficiency and emissions.
US08192687B2 Method and system for measuring water hardness
Prior to adding detergent or chelant, the conductivity of water in a washing chamber is measured. The maximum concentration of hard water ions that could correspond to the measured conductivity is determined, i.e., it is assumed that all of the conductivity is from calcium and/or magnesium ions in the water even though other ions may in fact be contributing to the measured conductivity. Enough chelating agent is added to the chamber to sequester this maximum concentration of hard water ions and the conductivity is measured again. Using the two conductivity measurements, the actual concentration of hard water ions is determined. A chelant factor based on the actual concentration of hard water ions is then used to determine the amount of chelant to be added for subsequent wash cycles to sequester all of the hard water ions.
US08192686B2 Apparatus for and method of measuring bio-chips using uniform total internal reflection illumination
Disclosed herein is an apparatus for and method of measuring bio-chips, which can implement an illumination method of a novel type that illuminates a bio sample (which may be also referred to as a “bio specimen”) through a side face of a substrate using a diffusion plate to form an evanescent field by the illumination light over the entire surface of a substrate so as to uniformly secure brightness of the illuminated light over a wide area of a substrate, thereby more efficiently measuring fluorescence information of a bio-chip over a wide field of view.
US08192682B2 High strength alloys
High strength metal alloys are described herein. At least one composition of a metal alloy includes chromium, nickel, copper, manganese, silicon, niobium, tungsten and iron. System, methods, and heaters that include the high strength metal alloys are described herein. At least one heater system may include a canister at least partially made from material containing at least one of the metal alloys. At least one system for heating a subterranean formation may include a tublar that is at least partially made from a material containing at least one of the metal alloys.
US08192681B2 Apparatus and method for clean, rapidly solidified alloys
One non-limiting embodiment of an apparatus for forming an alloy powder or preform includes a melting assembly, an atomizing assembly, and a collector. The melting assembly produces at least one of a stream of a molten alloy and a series of droplets of a molten alloy, and may be substantially free from ceramic in regions contacted by the molten alloy. The atomizing assembly generates electrons and impinges the electrons on molten alloy from the melting assembly, thereby producing molten alloy particles.
US08192680B2 Method for firing ceramic honeycomb bodies in a kiln
A method for fabricating ceramic honeycomb structural bodies that includes conveying at least one green honeycomb structural body of a first type and at least one green honeycomb structural body of a second type through a kiln in a manner which reduces cracking or fissures in the fired objects.
US08192677B2 Core/shell polymer and fluoropolymer blending blow molding and blown film process
A process is provided for extruding a partially crystalline melt-fabricable perfluoropolymers. The process comprises blow molding from a perfluoropolymer having polytetrafluoroethylene sub-micrometer particles dispersed therein. The perfluoropolymer composition is a core/shell polymer, with pelletized blend, a dispersion blend or a melt-mixed polymer.
US08192674B2 Process and apparatus for the production of a structure, in particular an aircraft structure, from a fiber composite material
The invention concerns an apparatus and a process for the production of a structure from fiber composite material, comprising a mold tool for receiving material which can be joined to provide a structure, and a vacuum system for molding and fixing the structure, wherein the vacuum system has a flexible layer, in particular a separation film or separation layer and/or a tear-off film, and a vacuum film for covering the structure. In accordance with the invention the vacuum system is free from ventilation material and/or tear-off material at least at a portion which corresponds to a portion of the structure to be covered, in which a step extends.
US08192672B2 Method for producing a retention matrix comprising a functional liquid
A method for fabricating a device provided with one or more cavities filled with at least one liquid, comprising the steps of: (a) forming one or more microcavities on a support separated from each other by one or more walls, and filled with at least one given porous material; (b) filling, in at least one cavity filled with said porous material, by means of at least one given functional liquid; and (c) forming a sealing layer enabling said cavities to be sealed.
US08192671B2 Method for manufacturing a door upper module for a window panel of a vehicle
The present invention relates to a method of manufacturing an opening leaf upper module intended to be mounted at the periphery of a glass panel of a vehicle, and to an opening leaf upper module of this type particularly comprising a rigid frame and a flexible weather strip.The method of manufacturing an opening leaf upper module (1) according to the invention, comprising a molded frame (3) based on at least one thermoplastic polymer and a molded weather strip (4) secured to the frame and based on at least one elastomer, comprises a step whereby a moving-platen mold or alternatively transfer molding is used to perform multiple-shot injection molding of materials that are intended to form the frame and the strip which are injected in succession, the elastomer being a thermoplastic elastomer compatible with this thermoplastic polymer, so as to obtain the module formed as a single piece.For preference, the strip comprises a continuous wiping lip (8) for wiping the glass panel and an interface lip (9) for interfacing with the bodywork (10) of the vehicle, and the frame has a longitudinal hollow (3b).
US08192670B2 Tire forming mold and tire manufacturing method
A tire forming mold has a side mold portion and an annular mold portion fitted to an outer side in a tire diametrical direction of the side mold portion at a time of clamping the mold, wherein the annular mold portion is constructed by a combination of sectors which are divided in a tire circumferential direction, and each of the sectors is capable of displacing in the tire diametrical direction, wherein a fitting diameter of the annular mold portion is set to be equal to or more than a fitting diameter of the pair of side mold portions, an annular rubber introduction groove extending along the tire circumferential direction is provided at least in one of a fitting surface of the annular mold portion and a fitting surface of the pair of side mold portions, and a shallow groove portion is formed in an introduction port of the rubber introduction groove.
US08192660B2 Cold-water soluble extruded starch product
Disclosed is a cold-water soluble starch and a process for preparing same. Generally, the process comprises providing a hydroxyalkyl starch and applying a shearing force to the starch in an extruder in the presence of moisture, the force and the moisture each being sufficient to gelatinize at least substantially all of the granules of the starch to thereby form a sheared starch. The starch is heated to its gelatinization temperature after the starch has passed partially through the barrel of the extruder, with the moisture being maintained at a level sufficiently high to allow gelatinization but sufficiency low to protect the starch from becoming too sticky to extrude. The extruded starch product thus formed may be used in connection with a number of film-forming, coating, and other applications.
US08192659B1 Methods of making microtablets for drug delivery
Methods and systems are provided for making a drug microtablet. The method includes loading a lyophilization capillary channel with a liquid drug solution; lyophilizing the liquid drug solution in the lyophilization capillary channel to produce a lyophilized drug formulation; compressing the lyophilized drug formulation in the lyophilization capillary channel, or in a compression capillary channel, to form a microtablet; and ejecting the microtablet from the lyophilization capillary channel or compression capillary channel. The methods and systems may provide drug microtablets having improved content uniformity and reduced weight variability.
US08192654B1 Method for producing an equal pitch extruded lenticular sheet
Disclosed herein is a method for producing a lenticular sheet comprising the steps of providing a substrate of transparent material having a first side and a second side; and engraving a cylinder with an inverse lens pattern, the inverse lens pattern being comprised of a plurality if inverse lenticule shapes, each inverse lenticule shape having an incremental pitch relative to the others; and using the engraved cylinder in an extrusion embossment process such that the substrate can be embossed with the inverse lens pattern, wherein the lenticular sheet produced comprises a lens pattern having a plurality of lenticules each of a uniform pitch relative to one another.
US08192652B2 Tin-doped indium oxide thin films and method for making same
The tin-doped indium oxide thin film in accordance with the present invention has a tin-doped indium oxide, yttrium ions and europium ions, wherein the yttrium ions are proportional to 0.1-10 mol % of the tin-doped indium oxide while the europium ions proportional to 0.05-5 mol % of the tin-doped indium oxide. The method in accordance with the present invention comprises preparing a tin-doped indium oxide; and doping yttrium ions proportional to 0.1-10 mol % of the tin-doped indium and europium ions proportional to 0.05-5 mol % of the tin-doped indium oxide in the tin-doped indium oxide using a film-manufacturing method.
US08192649B2 Capped poly(arylene ether) composition and method
A method of preparing a capped poly(arylene ether) resin includes reacting a capping agent with a blend of two or more poly(arylene ether) resins having different intrinsic viscosities. Cured compositions prepared from these capped poly(arylene ether) resins exhibit improved balances of stiffness, toughness, and dielectric properties compared to compositions with two or more separately capped and isolated poly(arylene ether) resins.
US08192648B2 Method for forming a sintered semiconductor material
A method of forming a material from a source material including the following steps of grinding the source material to get powders if the source material is not already in the form of powders; sintering the powders with at least one compression step and one thermal processing step; and purifying the material with a gas flow, the gas flow passing through the porosity channels of the material.
US08192645B2 Liquid crystal polyester resin composition for camera module
A resin composition for surface-mountable (SMT) camera modules which is excellent in the balance between heat resistance, rigidity, strength or moldability and surface exfoliation characteristics is provided by using a liquid-crystal polyester resin composition which comprises 100 parts by mass of a liquid-crystal polyester, 15 to 60 parts by mass of talc having a number-mean particle diameter of 10 to 50 μm, 25 to 50 parts by mass of glass fiber having a number-mean fiber length of 100 to 200 μm, 6 to 20 parts by mass of titanium oxide, and 2 to 10 parts by mass of carbon black and which exhibits a melt viscosity of 10 to 100 Pa S as determined at a shear rate of 100 sec−1 and 370° C. and a deflection temperature under load of 220° C. or above.
US08192638B2 Method for manufacturing multiple layers of waveguides
A method for manufacturing multiple layers of waveguides is disclosed. Initially, a first cladding layer is deposited on a substrate, a first inner cladding layer is then deposited on the first cladding layer, and a first waveguide material is deposited on the first inner cladding layer. The first inner cladding layer and the first waveguide material are then selectively etched to form a first waveguide layer. Next, a second inner cladding layer followed by a second cladding layer are deposited on the first waveguide layer. The second inner cladding layer and the second cladding layer are removed by using a chemical-mechanical polishing process selective to the first waveguide material. A third inner cladding layer followed by a second waveguide material are deposited on the first waveguide material. The third inner cladding layer and the second waveguide material are then selectively etched to form a second waveguide layer. Finally, a fourth inner cladding layer followed by a third cladding layer are deposited on the second waveguide layer.
US08192631B1 Fluid treatment device and method
An apparatus and method for treating raw water. The apparatus includes a vessel having an inlet for the raw water, an outlet for the skimmed water, a rotor mechanism for creating a plurality of gas bubbles within the raw water, and a disperser device operatively associated with the rotor mechanism for dispersing the plurality of gas bubbles from the rotor mechanism within the vessel. The vessel contains raw water. The gas bubbles create an oily froth on top of the raw water. The apparatus further includes a skim tray positioned about the rotor mechanism for removing the oily froth from the top of the raw water and a secondary skimmer positioned within the skim tray. An external skim tank may be configured to deliver a gas to the rotor mechanism and to receive the oily froth from the secondary skimmer.
US08192626B2 Wastewater chemical/biological treatment method for open water discharge
A wastewater treatment method employing chemicals for disinfection, and precipitation of suspended solids, heavy metals and phosphates before subsequent aerobic bacterial biological treatment using Nitrosomonas and Nitrobacter bacteria to remove ammonia and nitrates/nitrites and BOD compounds to produce recovered treated wastewater suitable for open water discharge.
US08192618B1 Ultrasonic dialyzer
In the present invention, dialysis tubing is placed in a chamber, where an ultrasonic or a other mist producer is present. The ultrasonic mist producer will produce mist and small water droplets will be attached to the surface of dialysis membrane (sheet or tubing) and will condense and the water drops will fall back in the solution tank, where the ultrasonic probe produces the mist. When the droplet is attached to the membrane surface, the dialysis will take place.
US08192613B2 Method for reducing fouling in furnaces
Heat exchanger fouling in organic chemical production processes may be reduced using an antifoulant additive. The antifoulant additive may have one component selected from the group consisting of an alkylphosphate ester, and an alpha olefin maleic anhydride copolymer; or it may have two components selected from the group consisting of a metallic overbase, an alkylphosphate ester, and an alpha olefin maleic anhydride copolymer, wherein at least one of the two components in not an overbase. An additive having three components: a metallic overbase, an alkylphosphate ester, and an alpha olefin maleic anhydride copolymer; is also within the scope of the disclosure.
US08192611B2 Small volume in vitro analyte sensor and methods of making
A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.
US08192610B2 Error detection in analyte measurements based on measurement of system resistance
Measurement of the series track resistance of a working and counter electrode pair in an electrochemical test strip provide error detection for multiple variations in the quality of the test strip, as well as the operation of strip in the test meter. In particular, a single measurement of series resistance can be used to detect and generate an error message when an incorrect reading is likely to result due to (1) damaged electrode tracks, (2) fouled electrode surfaces, (3) dirty strip contacts, or (4) short circuit between the electrodes.
US08192606B2 Device and a method for metal plating
A device and a method for metallic electrolytic coating of an object of electrically conductive material, wherein the object has at least two surface portions that are desired to be coated with layers of different thicknesses. The device includes an anode. The device is designed to receive the object in such a way that the object constitutes a cathode and that, upon receipt of the object, a space is formed for receiving a liquid-absorbing material and an electrolyte for coating the object. The body of the anode includes at least two surface portions) that have different electrical conductivity and that are arranged opposite to the surface portions of the received object.
US08192605B2 Metrology methods and apparatus for nanomaterial characterization of energy storage electrode structures
Embodiments described herein generally relate to methods and apparatus for forming an electrode structure used in an energy storage device. More particularly, embodiments described herein relate to methods and apparatus for characterizing nanomaterials used in forming high capacity electrode structures for energy storage devices. In one embodiment a process for forming an electrode structure for an energy storage device is provided. The process comprises depositing a columnar metal structure over a substrate at a first current density by a diffusion limited deposition process, measuring a capacitance of the columnar metal structure to determine a surface area of the columnar metal structure, and depositing three dimensional porous metal structures over the columnar metal structure at a second current density greater than the first current density.
US08192601B2 Electroblotting cassette with manually releasable electrodes of adjustable spacing
An electroblotting cassette is formed in three separable parts—an upper plate, a lower plate, and a base that receives both plates, with electrodes mounted on both the upper and lower plates. The cassette accommodates transfer stacks of different thicknesses by its inclusion of a set of raised areas, known as “lands,” on the floor of the base and a set of inverse lands on the underside of the lower electrode plate, the two sets being spatially arranged to either abut each other or be offset from each other, depending on the orientation of the lower plate, thereby allowing the user a choice between two heights of the lower plate within the base and hence two thicknesses of transfer stacks. Other arrangements include those with more than one set of lands on one or both parts to allow for three or more thickness selections, or depressions in place of lands. Finger-operated latches secure the upper plate to the base.
US08192600B2 Solid state device
A system that incorporates teachings of the present disclosure may include, for example, a solid-state selector having a vessel for carrying a liquid medium with one or more molecules surrounded by ions, a solid state conductive structure doped with impurities having one or more through-holes extending between two surfaces of the solid state conductive structure positioned within the liquid medium of the vessel, a voltage source coupled to the solid state conductive structure to selectively stimulate the ions surrounding the one or more molecules to pass through the one or more through-holes. Additional embodiments are disclosed.
US08192598B2 End-block for a magnetron device with a rotatable target, and vacuum coating apparatus
An end block for a magnetron device having a rotatable target comprises an end block housing having a pivot bearing. The end block housing is adapted on its outer side for attachment on a support unit, and the pivot bearing is adapted on an end that is accessible from outside the end block housing, for connection to the rotatable target. The end block housing is movably attached on the support unit. A vacuum coating apparatus has a vacuum chamber, a magnetron device situated in the vacuum chamber, and a rotatable target rotatably mounted on at least one such end block.
US08192597B2 Coating apparatus
A coating apparatus (100) for batch coating of substrates is presented. In the batch coater layers of a stack can be deposited by means of physical vapor deposition, by means of chemical vapor deposition or by a mixture of both processes. When compared to previous apparatus, the mixed mode process is particularly stable. This is achieved by using a rotatable magnetron (112) rather than the prior-art planar magnetrons. The apparatus is further equipped with a rotatable shutter that allows for concurrent or alternating process steps.
US08192592B2 Methods of forming a phase-change material layer including tellurium and methods of manufacturing a phase-change memory device using the same
The present invention provides methods of forming a phase-change material layer including providing a substrate and a chalcogenide target including germanium (Ge), antimony (Sb) and tellurium (Te) at a temperature wherein tellurium is volatilized and antimony is not volatilized, and performing a sputtering process to form the phase-change material layer including a chalcogenide material on the substrate. Methods of manufacturing a phase-change memory device using the same are also provided.
US08192589B2 Purification of aqueous solutions of organic acids
The invention relates to a method and a device for the purification of an aqueous solution of an organic acid having a boiling point at atmospheric pressure of less than 450° C., which further has approximately 275 g carboxylate ions/l or less, preferably 250 g carboxylate ions/l or less, and preferably less than 1% by weight ionic impurities, calculated on the basis of the total solution. In particular, the invention relates to a method and a device for the continuous purification and concentration, on an industrial scale, of an aqueous solution of an organic acid having a boiling point at atmospheric pressure of less than 450° C. According to the method, this solution is subjected to two or more distillation steps, the first distillation step being carried out at a temperature of from 80° to 150° C. and a pressure of from 50 to 250 mbar, and the second distillation step being carried out at a temperature of from 80° to 200° C. and a pressure of from 0.01 to 50 mbar.
US08192585B2 Shoe press belt
A press belt 20 includes a multiplicity of drain grooves 21 extending along a belt travel direction, lands 22 located between adjacent drain grooves 21, and auxiliary grooves 23 located on the lands 22 and extending along the belt travel direction. A transverse sectional area of each auxiliary groove 23 is smaller than that of each drain groove 21.
US08192582B2 Apparatus and method for stabilizing a moving web
Devices and methods related to a web stabilizer for stabilizing a moving web with a surface adjacent the moving web and with a supply of moving fluid in a direction parallel to the moving web and a supply of moving fluid in a direction perpendicular to the moving web.
US08192579B2 Method for forming color filter, method for forming light emitting element layer, method for manufacturing color display device comprising them, or color display device
After a gate line (11), a TFT (1), and a data line (30) are formed, a riblike protective insulation layer (32) which coats the data line is formed on a substrate (10) serving as the element substrate of an active matrix type color liquid crystal display device or an organic EL display device. A color filter layer (42) on a transfer film (40) is press-bonded on this substrate (10) with a roller (46) moving in the extensional direction (columnar direction) of the protecting insulation layer (32). The advancement of the transfer of a color filter in the columnar direction makes it possible to bring the substrate and the color filter in contact without gaps while expelling the gas out of a pixel space in the advancement direction. During the step of forming a color filter, the protecting insulation layer (32) protects the data line (30) from the treatment liquid etc. An organic light emitting element layer is arranged in the pixel space to form an organic EL display device.
US08192577B2 Focus ring, plasma etching apparatus and plasma etching method
In a plasma etching apparatus for performing a plasma etching on a surface of a substrate mounted on a susceptor in a processing vessel, a focus ring is installed to surround the substrate and has a first region at an inner side on a surface thereof, in which an average surface roughness is small such that a reaction product produced during an etching processing is not captured to be deposited, and a second region at an outer side from the first region, in which an average surface roughness is large such that a reaction product produced during the etching process is captured to be deposited. A boundary between the first and the second region is a part where an etching amount is relatively significantly changed compared to other parts while the focus ring is equipped in the plasma etching apparatus and the plasma etching is performed on the substrate.
US08192576B2 Methods of and apparatus for measuring and controlling wafer potential in pulsed RF bias processing
Apparatus and methods are provided to detect and control a voltage potential applied in a plasma chamber for processing a semiconductor wafer. The plasma chamber includes circuitry for monitoring and adjusting a pulsed RF bias voltage signal to be applied to a chuck in the plasma chamber, where the chuck is configured to mount the wafer for processing. The circuitry includes an RF bias voltage detector for detecting individual pulses of the pulsed RF bias voltage signal applied to the chuck. A timing circuit is provided for determining a time for sampling each of the individual detected pulses and a sample and hold circuit. The sample and hold circuit is triggered at the sampling time for sampling each of the individual detected pulses to determine and hold a voltage value representing a peak peak-to-peak voltage value of each individual detected pulse, and the sample and hold circuit is configured to provide a feedback signal representing the peak peak-to-peak voltage value of at least one of the detected pulses. Further included is a feedback circuit for adjusting the voltage of the pulsed RF bias voltage signal applied to the chuck according to a difference between the feedback signal and a desired voltage value of the RF bias voltage signal.
US08192573B2 Apparatus and method for applying labels supplied from a roll to containers
An apparatus and a method for applying labels (100) supplied from a roll for the labeling of containers (10) are disclosed. The containers (10) are fed to a labeling station (12). A cutting device (1) provides the required length (103) of the labels (100). The cutting device (1) can be variably controlled according to the circumference of the container (10).
US08192572B2 Composite wind turbine tower and a method for fabricating same
A method for fabricating a tower or component thereof for use with a wind turbine is disclosed. The method comprises weaving a fibrous tow in a shape corresponding to the shape of the tower or component to form a flexible textile preform; and laminating the flexible textile preform to form a composite shell. Also disclosed is a wind turbine assembly comprising a composite wind turbine tower and a wind turbine coupled to the tower.
US08192568B2 Non-toxic percussion primers and methods of preparing the same
A percussion primer composition including at least one explosive, at least fuel particle having a particle size of about 1500 nm or less, at least one oxidizer, optionally at least one sensitizer, optionally at least one buffer, and to methods of preparing the same.
US08192567B2 Composite solid rocket propellant with DCPD binder
A composite solid rocket propellant comprising a fuel, an oxidizer and a dicyclopentadiene binder is provided. The dicyclopentadiene binder may be mixed with the fuel and oxidizer as a monomer and then polymerized after mixing to form the composite solid propellant. The composite solid propellant may also comprise plasticizers, triphenylphosphine, lecithin or combinations thereof. Methods for making the composite solid rocket propellant of the present invention are also provided.
US08192563B2 Actuator
An actuator (12) is disclosed for example controlling gas flow in a gas turbine engine. The actuator (12) comprises a first portion (14) having shape memory properties, and a second portion (16) formed of substantially the same material as the first portion and having reduced shape memory properties relative to the first portion. The first portion (14) is movable from a first position to a second position at a temperature above the phase transition temperature of the shape memory material of the first portion (14). The second portion (16) is arranged to urge the first portion (14) from the second position to the first position at a temperature below the phase transition temperature of the shape memory material.
US08192559B2 High pressure tube cleaning apparatus
An assembly for rotating and axially directing a high pressure spray hose and spray head to clean residue from tubing bores. Modular, remotely controlled subassemblies are concentrically aligned and mounted to a hose drive framework to rotate in synchrony and direct a high-pressure water hose and spray head. A hose drive assembly controls hose rotation and axial hose movement via biased pinch wheels. A resilient, eccentric linkage controls pinch wheel pressure. A layering arm uniformly layers the hose at a hose reel. Rotational sensors and/or a pneumatic booster and a disk brake assembly facilitate non-kinking hose collection and release without spillage. A re-configurable hose support framework contains a driven walking beam having drive assemblies that laterally and vertically index a hose support and control the inclination of the walking beam.
US08192558B2 Drain system for a warewasher
A conveyor warewasher for washing wares includes a first tank including a drain system having a drain outlet and a drain stop movable between a drain outlet closed position and a drain outlet open position. A second tank includes a drain system having a drain outlet, an associated drain path that leads to the first tank and an associated drain path stop moveable between a drain path open position and a drain path closed position. A drain control assembly includes a common drain actuator operatively connected to cause both (i) movement of the drain stop from the drain outlet closed position to the drain outlet open position and (ii) movement of the drain path stop from the drain path closed position to the drain path open position.
US08192556B2 Pickling or brightening/passivating solution and process for steel and stainless steel
The use of complex fluoride ions of elements of groups 4, 13, or 14 of the periodic table of the chemical elements (preferably selected from complex fluoride ions of the elements B, Si, Ti, and Zr) in concentrations from 30 t 500 millimoles per liter in process solutions for pickling steel or for bleaching and/or passivating pickled surfaces of stainless steel; a process solution for pickling steel or bleaching and/or passivating pickled surfaces of stainless steel comprising: a) one or more strong acids, b) one or more oxidizing agents in the bleaching/passisvating process, c) complex fluoride ions of elements of groups 4, 13 or 14 of the periodic table of the chemical elements in concentrations from 50 to 500 mmoles per liter; replenisher or concentrate containing a combination of active substances thereof; a process for pickling steel or for brightening and/or passivating of pickled surfaces of stainless steel, wherein the surfaces are brought into contact with such a process solution.
US08192555B2 Non-chemical, non-optical edge bead removal process
A method for removing the edge bead from a substrate by applying an impinging stream of a medium that is not a solvent for the material to be removed. The medium is applied to the periphery of the substrate with sufficient force to remove the material. Also an apparatus to perform the inventive method.
US08192552B2 Detergent composition comprising a block copolymer
The invention relates to a detergent composition, suitable for use in dish washing or laundry, comprising at least 15% of a detersive surfactant(s), and a block copolymer, selected from the group consisting of (block A)-(block B) diblock copolymers, (block A)-(block B)-(block A) triblock copolymers, and (block B)-(block A)-(block B) triblock copolymers, wherein block A and block B derive from alpha ethylenically unsaturated monomers, at least one block being water-soluble. The detergent compositions provide an increased cleaning, and/or a decreased redeposition of the fatty substances once they are removed from a substrate.
US08192551B2 Obstacle sensing spray arm for a dishwashing machine
A dishwashing machine includes a washing chamber, a spray arm, and a sensor. The sensor provides data regarding the rotation of the spray arm. The direction of rotation of the spray arm is reversed in response to a control signal generated when a load on the spray arm exceeds a predetermined limit.
US08192550B2 Use of an aqueous neutral cleaning solution and method for removing rouging from stainless steel surfaces
The invention relates to a method for removing films and deposits from stainless surfaces, especially from stainless metallic surfaces such as they are used in process stations and production units in the pharmaceutical, food and biotechnological industries, and to an aqueous cleaning solution comprising a reducing agent, in particular dithionite and/or disulfite, and at least two different complexing agents, wherein one of these complexing agents is a compound comprising diacetic acid groups or a salt thereof, for removing rouging on surfaces of stainless steels that come into contact with media selected from the group of chromium/nickel and chromium/nickel/molybdenum steels in the neutral pH range.
US08192547B2 Thermally isolated cryopanel for vacuum deposition systems
The present invention relates to vacuum depositions systems and related deposition methods. Vacuum deposition systems that use one or more cyropanels for localized pumping of a deposition region where a substrate is positioned are provided. The present invention is particularly applicable to pumping and minimizing reevaporation of high vapor pressure deposition materials during molecular beam epitaxy.
US08192546B2 Deposition apparatus
A deposition apparatus including: a chamber; a mask assembly including a mask arranged to deposit a material on a substrate included in the chamber and a mask frame for supporting the mask; and a magnet unit including a first magnet unit which contacts (or adheres or chucks or secures) the mask assembly to the substrate by magnetic force; and a second magnet unit corresponding to the mask frame, in order to ensure that the mask more closely contacts the substrate.
US08192545B2 Film formation apparatus, method for forming film, and method for manufacturing photoelectric conversion device
The present invention relates to a film formation apparatus including a first transfer chamber having a roller for sending a substrate, a film formation chamber having a discharging electrode, a buffer chamber provided between the transfer chamber and the film formation chamber or between the film formation chambers, a slit provided in a portion where the substrate comes in and out in the buffer chamber, and a second transfer chamber having a roller for rewinding the substrate. The slit is provided with at least one touch roller, and the touch roller is in contact with a film formation surface of the substrate. In addition, the present invention also relates to a method for forming a film and a method for manufacturing a photoelectric conversion device that are performed by using such a film formation apparatus.
US08192544B2 Apparatus for manufacturing poly crystaline silicon ingot for solar battery having door open/close device using hinge
Disclosed herein is an apparatus for manufacturing a polycrystalline silicon ingot for solar batteries having a door control device using a hinge. The apparatus includes a vacuum chamber, a crucible, a susceptor which surrounds the crucible, a heater which heats the crucible, and an insulation plate which is disposed below the susceptor and has an opening therein. The apparatus further includes a cooling plate which moves upwards through the opening of the insulation plate and comes into close contact with or approaches the lower end of the susceptor, a cooling plate moving unit which actuates the cooling plate, a temperature sensor which measures the temperature of the crucible, and a control unit which controls the temperature in the crucible and the cooling plate moving unit. Furthermore, a door is provided on the insulation plate to open or close the opening of the insulation plate. The hinge is provided between the door and the insulation plate. Thus, after the raw silicon material is melted, when the cooling plate moves upwards to cool the crucible and thus pushes the lower surface of the door upwards, the door is opened by the hinge in a swinging manner, and when the cooling plate approaches or comes into contact with the lower end of the susceptor, one end of the opened door is leaned on a corresponding surface of the cooling plate.
US08192542B2 Aqueous suspension based on hydraulic binder and a process for the production thereof
Method for producing an aqueous suspension, which is based on a hydraulic binder, and a hardened binder product. According to the invention, a composition of blending agents is added in the aqueous phase into the binder, which composition comprises calcium carbonate particles having an average particle size of 2-200 nm, in order to generate an aqueous suspension and, if needed, mineral fillers are added into this suspension, in order to produce a hardening plaster or concrete mixture. Besides calcium carbonate, the composition of blending agents can comprise calcium hydrogen carbonate and meta-kaolin sinter, too. By using the present invention, it is possible to improve the properties of products which are bound by hydraulic binders; with the described combination of blending agents it is possible to affect for instance the early strength, the frost resistance, the phenomenon of bleading, the plasticizing, the size of the transition zone and the durability of concrete or plaster, and to reduce the quantity of the hydraulic binder.
US08192540B2 Color powder for coating
A method for producing a bonded color powder concentrate, the method comprising dry mixing a base powder, a pigment powder and a bonding agent; and during the dry mixing, applying heat so as to bring the bonding agent to an adhesive state while the base powder and the pigment powder remain in a stable state, thereby forming agglomerates essentially each comprising a component of the base powder and a component of the pigment powder, bonded together using a component of the bonding agent.
US08192534B2 Open lumen air filtration for liquid lines
Devices and systems for capturing and removing accumulated gas bubbles in a liquid-carrying line wherein the device is an expanded double-layered chamber designed and adapted to be integrally placed within the flow pathway of a liquid-carrying line. The device allows insertion of tubes and wires through the device while in use without occlusion of the fluid flow path and without interruption of the bubble-removing function. The efficiency of the air venting and bubble-removing process is not dependent on the fluid flow rate under stable flow conditions, and the device works to remove air bubbles under a range of orientations.
US08192529B2 Integrated dry scrubber system
An air quality control system (AQCS) (4) useful for processing a gas stream (DG), such as a flue gas stream emitted from a fossil fuel fired boiler (2), combustion process or the like, for at least partial removal of acidic and like contaminants. The air quality control system (4) includes a plurality of integrated components (12) equipped with both a dry scrubber system (8) and a fabric filter (10). The air quality control system (4) such as described possesses increased “turn down” capabilities thus increasing the efficiency thereof.
US08192527B2 Purification method by hydrogen adsorbtion with cogeneration of CO2 stream pressure
The present invention relates to a method of producing hydrogen of very high purity from a feed predominantly containing said hydrogen and a minor part of impurities mainly consisting of carbon dioxide, carbon monoxide, methane and heavier hydrocarbons. The purification method by hydrogen adsorption using a desorption stage at a lower pressure than the pressure of the feed, such as a PSA method for example, allows to produce the desorption stream and notably to recover the carbon dioxide under pressure and high-purity hydrogen, with a high yield. These performances are obtained by combining the successive stages of the method according to the invention with the use of a new family of adsorbent whose dynamic capacity at a high desorption pressure is greater than that of conventional adsorbents.
US08192519B2 Beneficiated, heat-dried biosolid pellets
This invention is directed to systems, devices and methods for modifying the process of producing dried biosolids pellets or granules into beneficiated inorganically-augmented bioorganic fertilizer. The present invention describes a method to beneficiate heat-dried biosolids or sludge pellets or granules as presently manufactured by municipalities or companies from a) dewatered municipal wastewater biosolids or sludges within the municipal wastewater treatment plant heat-dried biosolids production facility or from b) finished dry heat dried biosolids pellets or granules in a separate manufacturing facility from the municipal wastewater treatment plant to produce a fertilizer containing sufficient organic and inorganic plant nutrients to be valuable and saleable into the commercial agricultural industry. The present invention describes beneficiation methods to increase the plant nutrient content to a level which permits the finished beneficiated dried biosolids pellet or granule product to compete in the commercial agricultural fertilizer marketplace and also to reduce the odors associated with traditionally-produced heat dried biosolids.
US08192517B2 Ceramic honeycomb structural body
The ceramic honeycomb structural body comprises a pillar-shaped honeycomb structural porous ceramic member formed by arranging a plurality of through holes as a gas path side by side through partition walls or a combination thereof, in which the ceramic honeycomb structural body is a sintered body having a pore structure in which one or more peaks (the maximum value) exist in each region of a first pore group of pores having a pore size of about 0.05 μm to about 150 μm and of a second pore group of pores having a pore size of about 0.006 μm to about 0.01 μm.
US08192508B2 High dielectric constant ceramic-polymer composites, embedded capacitors using the same, and fabrication method thereof
Disclosed are ceramic-polymer composite consisting of aggregates of dielectric ceramic particles and polymer resin, and a fabrication method thereof, the method including aggregating dielectric ceramic particles to create aggregates, melting polymer resin in a solvent to prepare a polymer solution, dispersing the aggregates in the polymer solution to prepare a mixed solution, and hardening the mixed solution to obtain ceramic-polymer composites.
US08192507B1 Supercritical noble gases and coloring methods
Coloring compositions including, for example, a supercritical fluid comprising a noble gas in a supercritical state and a colorant within the supercritical fluid are disclosed. For example, the noble gas may be at least one of helium, argon, krypton, neon, xenon and radon. Methods of producing such compositions and methods of coloring an article with such composition are also disclosed.
US08192506B2 Compositions for dyeing keratin-containing fibers
Disclosed herein are compositions suitable for use in dyeing keratin-containing fibers. Further disclosed herein are colorant systems and compositions comprising the colorant systems. Also disclosed are kits comprising one or more colorant systems and an activator composition.
US08192501B2 Prosthetic knee with gravity-activated lock
Disclosed is a prosthetic knee appliance having upper and lower leg elements with a single-axis, articulating joint therebetween controllable with an electric knee-lock mechanism. A tilt-switch located within the prosthetic knee can facilitate activation of the electric knee-lock to lock or unlock the joint when the lower leg element is in a pre-determined position. A remote control can provide external locking control of the articulating joint. A pressure switch can ensure that the free-knee is locked only when the lower leg element is sufficiently extended relative to the upper leg element. The mobility of a free-knee system combined with the stability of a straight-leg prosthesis can be advantageous for pre-ambulatory pediatric patients.
US08192498B2 Posterior cructiate-retaining orthopaedic knee prosthesis having controlled condylar curvature
An orthopaedic knee prosthesis includes a tibial bearing and a femoral component configured to articulate with the tibial bearing. The femoral component includes a condyle surface curved in the sagittal plane. The radius of curvature of the condyle surface decreases gradually between early-flexion and mid-flexion. Additionally, in some embodiments, the radius of curvature may be increased during mid-flexion.
US08192495B2 Lockable spinal implant
A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration.
US08192494B2 Posterior metal-on-metal disc replacement device and method
Provided is a device and method for replacing a diseased or damaged intervertebral disc in the spine of a patient. The device provided having at least two units, each of the units having an articulation surface and a bone contacting surface, the articulation surfaces of each of the at least two being in articulating opposition one to the other, one of which having a convex articulation surface and the other having a complementary concave articulation surface. The bone contacting surfaces being provided with bone implantation securing elements such as keel type or spike type protrusions. Also provided is a method of implanting the device into an intervertebral space from a posterior approach.
US08192493B2 Prosthesis for bridging a vertebral body
A prosthesis for the partial replacement of a vertebral body includes an upper contact plate for connection to an upper vertebral body, a lower contact plate for connection to a lower vertebral body and a bridging part which connects the upper and lower contact plates to one another and bridges at least one intermediate vertebral body which is located between the upper and lower vertebral bodies and is to be partially replaced. The bridging part is accommodated in a recess in the vertebral body and is secured in the recess with lateral anchoring projections which penetrate into the bone substance located on both sides of the bridging part. The cross section of the bridging part may narrow toward the rear, preferably in a trapezoid shape.
US08192492B2 Spinal implant
A spinal implant as provided having a porous body that includes a leading end, a convex trailing end and first and second sides extending between the leading and trailing ends. At least a portion of the leading end is generally straight. The body further includes a generally dome-shaped superior surface and a generally planar inferior surface. The superior surface is convex between the leading and trailing ends and is convex between the first and second sides.
US08192483B2 Stent to be placed in the living body
It is intended to provide a stent to be placed in the living body which exhibits excellent extension properties even in a flexion site of a lumen in the body and shows a low restenosis rate after being placed in the living body. A stent to be placed in the living body characterized in that, as one of the characteristics thereof, the stent is in a long and thin tubular shape having both termini, the long and thin tubular body can be extended in the radial direction from the first diameter in the compressed state to the second diameter in the extended state, the stent has a first terminal section, a second terminal section, a third central section, a fourth section located between the first terminal section and the third central section and a fifth section located between the second terminal section and the third central section, the rigidity of the fourth section is lower than the rigidity of the first terminal section and lower than the rigidity of the third central section, and the rigidity of the fifth section is lower than the rigidity of the second terminal section and lower than the rigidity of the third central section.
US08192480B2 System and method of detecting implant detachment
A system and method of detecting implant detachment within the body of a patient. The activation of the heater coil causes the degradation, melting or reduction of a component that brings the heater coil into or out of electrical contact with another component, or causes the individual loops of the coil to contact each other, thereby resulting in a notable change in resistance in the circuit supplying the heater coil with electricity.
US08192479B2 Method and device for vascular therapy
Medical devices, as well as methods of treatment and manufacturing such devices, are provided for applying vascular therapy locally within the body vessel. The medical devices include an expandable tubular frame and a sleeve. The medical devices can be used for local delivery of a therapeutic agent within a body vessel or a tamponade for a lacerated body vessel, while simultaneously allowing perfusion of fluid or blood flow distal of the implanted medical device. The tubular frame of the medical device can have a middle region with a plurality of members. The members can expand radially outward away from a longitudinal axis of the tubular frame, which can urge the sleeve to contact the wall of the body vessel. In the expanded configuration, a portion of the device allows fluid flow to continue while the sleeve is against the body vessel wall.
US08192473B2 Phototherapy apparatus for hair, scalp and skin treatment
A wearable hands-free apparatus for providing phototherapy treatment to a number of hair, scalp and skin related conditions includes a head unit (e.g., a headset, headphones, headband, or helmet unit) with earphones to allow the user to listen to an audio program during a treatment. The head unit supports a light emitting canopy band that is fitted with an array of light generating sources, such as light emitting diodes (LEDs), laser diodes, or infrared lights, that emit light within a particular wavelength range correlating with the treatment of one or more specific hair, scalp and/or skin-related conditions. The light emitting canopy band is specifically designed to conform to the shape of the human scalp for providing complete, uniform and consistent light coverage to the areas of the scalp that are most commonly affected by hair loss in men and women. A handheld control device allows the user to select the desired treatment program and is adapted for connection to a digital audio player device, such as an MP3 player, for delivering audio signals to the earphones.
US08192461B2 Methods for facilitating closure of a bodily opening using one or more tacking devices
The present embodiments provide methods for facilitating closure of a bodily opening. In one exemplary method, at least a portion of a first tacking device is disposed through at least a portion of tissue at a first location in a vicinity of an opening in the tissue. Then, at least a portion of a second tacking device is disposed through at least a portion of tissue at a second location in the vicinity of an opening in the tissue. A closure member having at least one loop portion is advanced towards the first and second tacking devices, and the loop portion is positioned around at least a portion of the first tacking device and at least a portion of the second tacking device. The closure member then is actuated to urge the first tacking device towards the second tacking device to provide a compressive force upon the opening.
US08192460B2 Annular support structures
Reinforcing lumen rings are configured and adapted for use in conjunction with a circular endoscopic stapling instrument having a staple cartridge assembly and an anvil assembly. The reinforcing lumen rings maintain anastomotic lumen, e.g. as formed by the circular endoscopic stapling apparatus, in an open condition. The reinforcing lumen rings can include an annular ring having an outer terminal edge and an inner terminal edge, the outer terminal edge having a diameter which is substantially equal to an outer diameter of the staple cartridge assembly and the inner terminal edge having a diameter which is substantially equal to an inner diameter of the staple cartridge assembly.
US08192459B2 Blood vessel closure clip and delivery device
A clip for closing a puncture hole in a blood vessel comprises a ring having a resiliently expandable circumference and a plurality of barbed prongs extending at least approximately in the same direction from one edge of the ring. A device for deploying such a clip is also described.
US08192458B2 Surgical fastening system and method for using the same
A surgical fastening system for attaching one piece of tissue to another piece of tissue. The system comprises a surgical fastener, an installation tool for deploying the surgical fastener in tissue, and a method for using the same.
US08192457B2 Wound closure methods
Methods and devices are provided for closing a puncture wound. In one exemplary embodiment, a puncture closure device is provided having an elongate tubular body that is disposable through a puncture in tissue and that includes proximal and distal portions. The proximal portion can be adapted to expand to form proximal wings upon rotation of the elongate tubular body, preferably in a first direction. The distal portion can be adapted to expand to form distal wings upon rotation of the elongate tubular body, preferably in a second, opposite direction. The proximal and distal portions can also be adapted to be moved toward one another as they expand upon rotation. As a result, the proximal and distal wings can engage tissue therebetween.
US08192453B2 Surgical cutting tool and system
A surgical cutting tool, instrument, kit and system are disclosed, which are adapted for use during in total hip (or shoulder) replacement surgery. The invention optimally and efficiently removes excess bone (osteophytes) and soft tissue from the rim of a hemispherical component such as an implanted acetabular shell, prior to insertion of a liner. The surgical instrument includes an elongated obturator adapted to be removably attached to the acetabular component. An elongated reamer tool has a cannulated central boss for receiving the obturator. The tool has an upper end adapted to be coupled to a powered tool driver, and a lower end provided with a pair of spaced apart blades adapted to engage the rim of the acetabular component and be driven to remove the excess bone fragments from the rim of the implanted shell component.
US08192452B2 Easily cleaned atherectomy catheters and methods of use
An atherectomy catheter is provided having a tissue collection chamber capable of being cleaned out in a simple, fast and effective way, and also provides methods of using said catheter to remove material from a blood vessel lumen. In one embodiment the tissue collection chamber has an expandable tip having a first closed position capable of retaining material in the chamber and having a second open position that may allow expulsion of material from the chamber. In a second embodiment the tissue collection chamber has a displaceable tip having a first closed position to retain material in the chamber and having a second open position to allow expulsion of material from the chamber.
US08192443B2 Pedicle access device
A pedicle access device that has particular application for positioning a pedicle screw during a minimally invasive spinal fusion surgical procedure. The pedicle access device includes a positioning needle having a hollow tube and a specially designed tip that conforms with a facet complex of a vertebra proximate a pedicle. A targeting needle having a pointed end is inserted through the hollow tube of the positioning needle, and is secured thereto so the tip of the targeting needle extends out of the end of the positioning needle. The tip of the targeting needle allows the positioning needle to be accurately positioned on the pedicle, and the specially configured tip of the positioning needle allows it to be secured thereto without slipping.
US08192439B2 Minimally invasive surgical system
A minimally invasive surgical system for implanting pedicle screw assemblies to be connected by a spinal rod is disclosed. In one form, the system includes a plurality of holding mechanisms for the pedicle screw assemblies, each holding mechanism for being inserted through an incision and configured to receive tools along an axis thereof for driving a screw anchor of the pedicle screw assembly into a vertebra and securing the spinal rod thereto and a rod inserter that is configured to adjustably hold the rod and insert the rod through a common incision with one of the holding mechanism for being fed into position in an initial direction that is transverse to the axes of the holding mechanisms.
US08192435B2 Devices and methods for tissue modification
Methods and apparatus are provided for selective surgical removal of tissue, e.g., for enlargement of diseased spinal structures. The current invention includes specific tools that enable safe tissue modification in epidural space, including a barrier that separates the area where tissue modification will take place from adjacent vulnerable neural and vascular structures. In one variation, a tissue abrasion device is provided including a thin belt or ribbon with an abrasive cutting surface. The device optionally may be placed within a protective sheath that exposes the abrasive surface of the ribbon only in the area where tissue removal is desired.
US08192434B2 External fixation and foot-supporting device
In one preferred embodiment according to the present invention, an external fixation device for the foot and ankle of the human anatomical skeleton includes a yoke, three adjusters, and a base (or foot plate). The foot plate selectively couples to the yoke without the need of any tools, thereby enabling the patient to self attach and remove the foot plate from an existing circular fixation structure.
US08192430B2 Device for extracting an elongated structure implanted in biological tissue
A device for extracting an implanted elongated structure from biological tissue comprises a sheath having a plurality of lumens therein opening to the sheath distal end. First and second lumens are disposed along a wall of the sheath, and a third lumen is dimensioned to receive the elongated structure. The sheath wall having the first and second lumens disposed therein is alternately compressible and expandable responsive to a bend along a bending zone of the sheath. A first wire segment is positioned in the first lumen, and a second wire segment is positioned in the second lumen, wherein the respective proximal ends of the segments are affixed proximal to the bending zone. The respective wire segments extend distally in the respective first or second lumen a first distance beyond the distal end of the sheath when the bend compresses the wall surface generally adjacent the first and second lumens, and extend distally a second distance, less than the first distance, when the bend expands the wall surface.
US08192425B2 Radiofrequency perforation apparatus
A radiofrequency perforation apparatus for creating a channel at a target location in a body of a patient, the radiofrequency perforation apparatus being usable by an intended user having a hand, the radiofrequency perforation apparatus comprising: a handle graspable by the hand; a distal portion, the distal portion defining a distal portion length, the distal portion including an electrode and an electrical insulator extending from the electrode; and a force transmitting portion extending between the distal portion and the handle, the force transmitting portion defining a force transmitting portion length, the force transmitting portion length being larger than the distal portion length, the force transmitting portion having a force transmitting portion flexural rigidity of at least about 0.016 Nm2; whereby the force transmitting portion has a force transmitting portion flexural rigidity allowing the transmission to the handle of contact forces exerted on the distal portion when the distal portion contacts the target location to provide tactile feedback to the intended user.
US08192424B2 Electrosurgical system with suction control apparatus, system and method
System and method for selectively applying electrical energy to structures within or on the surface of a patient's body and controlling the flow of an electrically conductive fluid from the application site to provide or maintain a desired operating condition of the electrosurgical device. An electrosurgical probe is in communication with a fluid transport apparatus through a fluid transport lumen having an opening at an end proximate the application site and disposed proximate the electrosurgical probe. A controller in communication with the fluid transport apparatus provides control signals to the fluid transport apparatus in response to at least one operating parameter associated with the system. Based on the received control signals, the fluid transport apparatus adjusts a flow rate of the electrically conductive fluid at the application site through the fluid transport lumen in response to at least one operating parameter associated with the system.
US08192419B2 Catheter assembly including internal bolster
A catheter assembly including an internal bolster. According to one embodiment, the catheter assembly includes a medical catheter preferably made of extruded silicone rubber. The catheter is shaped to include a cylindrical wall defining a primary longitudinal bore. A plurality of secondary longitudinal bores is provided in the cylindrical wall, the secondary bores being evenly spaced around the primary bore. The assembly also includes a plurality of identical resilient members collectively forming an anchor at a first end of the catheter. Each resilient member comprises a resilient wire and a protective jacket. Each wire is made of a shape-memory material and is reversibly transformable between a spiral shape, when at rest, and a straightened shape, when forcibly unfurled. One end of each wire is disposed within a secondary bore of the catheter, with the remainder of each wire extending out from the catheter. Each jacket is preferably made of silicone rubber and encapsulates all of the length of its wire, except for the small portion of the wire inserted into the bore.
US08192418B2 Releasing a material within a medical device via an optical feedthrough
In general, the disclosure is directed toward releasing material within a medical device via an optical feedthrough. A system for releasing material with a medical device comprises a cup that holds a material, wherein the cup includes a discharge port, a seal disc that seals the material within the cup, an optical feedthrough assembly coupled to the cup, a shell that defines a chamber within a medical device, wherein the optical feedthrough assembly is coupled to the shell, and a radiant energy source that shines a beam through the optical feedthrough assembly to puncture the seal disc to allow the material to enter the chamber via the discharge port.
US08192413B2 External urinary catheter
The external urinary catheter comprises a sheath portion (1) and a tip portion (3). A layer of adhesive (7) is provided on the inner side of the sheath portion (1) and extends between a first limit (7a) and a second limit (7b). At least one indication (8) indicating at least the first limit (7a) of the layer of adhesive (7) is provided. The indication may be a visual indication, e.g. in the form of a colored line (8).
US08192410B2 Control device for surgical stoma
A control device for controlling drainage of waste from a surgical stoma of a human body. The control device comprises a first cylindrical hollow body member, a drain tube extending from the first cylindrical hollow body member, a second cylindrical hollow body member rotatably coupled to the first cylindrical hollow body member and a knob configured on the second cylindrical hollow body member. The first cylindrical hollow body member comprises a skirt portion extending radially outward for being removably attached to a surface surrounding the surgical stoma of the human body. The second cylindrical hollow body member comprises an aperture configured on the second sidewall. A rotation of the knob is capable of aligning the aperture of the second cylindrical hollow body member with the drain tube of the first cylindrical hollow body member thereby forming a passage for draining the waste.
US08192407B2 Syringe needle protective device and injecting device provided therewith
The inventive needle protective device (2) comprises a protective support (20), a movable needle protector (22), a compression spring (24) applied between the protective support (20) and the needle protector (22) and means (38, 40, 54) for initially holding the needle protector (22) oppositely to the compression spring (24) action, wherein said means (38, 40, 54) are releasable by the needle protector (22) displacement in a releasing direction with respect to the protective support (20). Said device also comprises mechanical means (45, 62) for locking the needle protector (22) actuatable by the action of a needle protective cap engaged into the end opening (60) of the needle protector (22) and deactivatable by the cap releasing.
US08192405B2 Trocar seal system
A seal assembly for reception of an elongated surgical instrument is provided which includes a body having at least one opening configured and dimensioned to permit entry of an elongated surgical instrument and defining a central longitudinal axis; a seal member formed of a resilient material and defining an aperture therein, the aperture being configured and dimensioned such that insertion of the surgical instrument into the aperture causes the resilient material defining the aperture to resiliently contact the outer surface of the surgical instrument in a substantially fluid tight manner; and a fabric layer juxtaposed relative to the resilient material. A coating may be applied to the seal member to reduce friction between the seal member and surgical instrumentation inserted therein. The coating is preferably a hydrocyclosiloxane membrane prepared by plasma polymerization process.
US08192400B2 Pneumatic injection device
The invention relates to a pneumatic injection device adapted to be connected with an air outlet of a dental chair for providing a compressed air flow, comprising: an injection unit comprising a unit body having a proximal end, a distal end and a cavity between the proximal and distal ends for receiving a dental cartridge, wherein the distal end has an injection needle connector for connecting a needle, and the proximal end is connected to an air seal adaptor in an airtight relationship; an output pressure selector having an output end connected air-tightly to the other end of the air seal adaptor; an air releasing means having an output end connected air-tightly to an input end of the output pressure selector; and an input pressure adjustor having an output end connected air-tightly to an input end of the air releasing means, an input end for connection to the air outlet of the dental chair.
US08192398B2 Medical device and medical instrument alignment
Systems and methods for orienting a medical instrument relative to at least a portion of a medical device include a first tilt detector associated with the medical instrument and a second tilt detector associated with the medical device. The first tilt detector may be within an orientation device that is coupled to or separate from the medical instrument. The tilt detectors generate signals that may be used to determine the relative orientation between at least a portion of the medical device and medical instrument. For example, in some embodiments, the signals may be used to determine whether the orientations of the portion of the medical device and the medical instrument substantially match.
US08192397B2 Medical fluid injection and inflation system
A combined fluid injection and inflation system is disclosed and includes a fluid delivery system including at least one pressurizing device, a fluid path, and a control unit. The fluid path is adapted to connect the pressurizing device to a patient via a catheter including a balloon and inserted in the patient. The control unit is operable to control the fluid delivery system. In operation, the control unit selectively actuates the fluid delivery system to operate in a fluid injection mode or in a balloon inflation mode. In the fluid injection mode the pressurizing device delivers fluid to the fluid path for a fluid injection procedure. In the balloon inflation mode, the pressurizing device delivers fluid to the fluid path for inflating the balloon associated with the catheter. An operator control may be connected to the control unit for controlling the fluid delivery system and may be a handheld device.
US08192395B2 System for providing blood glucose measurements to an infusion device
An infusion system includes a characteristic determining device and an infusion device. The characteristic determining device includes a receptacle for receiving and testing an analyte from the user to determine a concentration of the analyte in the user. The characteristic determining device also includes a communication system for transmitting a communication including data indicative of the determined concentration of the analyte in the user, and the infusion device includes a communication system for receiving the communication from the characteristic determining device. The infusion device further includes a bolus estimator for calculating an estimated amount of fluid to be infused into the body of the user based upon the received data indicative of the determined concentration of the analyte in the user and a target concentration of the analyte in the user, and an indicator to indicate when the estimated amount of fluid to be infused has been calculated.
US08192394B2 Method and system for manual and autonomous control of an infusion pump
A method and system for both autonomous and manual control of an infusion pump for delivering medication to a patient is provided.
US08192393B2 Method and apparatus for inserting a rectal suppository
Rectal suppositories are used to administer a predetermined drug dosage to treat a variety of diseases and symptoms in a variety of patient populations. Certain medical conditions, such as digestive disorders, may be more effectively treated when the suppository is placed in a particular location of the patient's anal canal or rectum. A method and apparatus for inserting a suppository into an animal or human may include an applicator having a barrel and plunger. The barrel maintains a first gas flow path during insertion of a suppository and the plunger maintains a second gas flow path during withdrawal of the plunger. By maintaining a first and second gas flow path, trapped air and suction effects on the suppository are minimized or eliminated. Furthermore, patients may immediately resume day-to-day activities. These benefits may encourage patients to maintain a course of treatment thereby potentially avoiding additional complications, hospitalization, and costs.
US08192390B2 Method and system for control of osmotic pump device
Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
US08192386B2 System and method for controlling hematocrit during a therapeutic red blood cell exchange procedure
Systems and methods for controlling hematocrit during a blood processing procedure. In one aspect, a system includes a first flow path for flowing whole blood from a patient. A separator communicates with the first flow path for separating at least red blood cells from plasma. Second and third flow paths communicate with the separator for respectively flowing the separated plasma and red blood cells from the separator. A flow controller is associated with the second and third flow paths to control fluid communication between the second and third flow paths and addition of separated plasma to the separated red blood cells. The resulting red blood cells and plasma has a resulting hematocrit. Hematocrit is calculated or sensed in operative association with the third flow path and communicated to the flow controller for controlling the amount of plasma added to the third flow path and the resulting hematocrit.
US08192379B2 Single-motor massager
A single-motor massager has a base, a carriage, a gear shaft assembly, a massager assembly and a motor. The base has two gear racks. The carriage is mounted movably on the base. The gear shaft assembly is mounted on the carriage and is mounted movably on the gear racks of the base. The massaging assembly is mounted on the carriage and connects to the gear shaft assembly. The motor drives the massaging assembly of the massager assembly to provide massaging function and to move the carriage and the gear shaft assembly and the massaging assembly along the base. With the two gear racks, the massaging assembly moves stably. With only one motor and the simplified gear shaft assembly and massager assembly, the manufacturing process of the massager is simplified and the cost of the massager is reduced.
US08192377B2 Physical therapy device
Disclosed herein is a device for supporting a human limb during the application of physical therapy to the limb, the device comprising a base, the base defining a base plane; a support member comprising an attachment end separated from a limb support end by a support distance, wherein the attachment end is movably engaged with the base such that the support member is moveable in a plane of motion essentially perpendicular to the base plane; and wherein the limb support end is conformable to a human limb and capable of supporting the human limb when physical therapy is being applied to the human limb. A method of stretching a human knee using the instant device is also disclosed.
US08192375B2 Apparatus and method for dynamically fitting insoles to a patient
In one aspect, the present invention is directed to an apparatus for dynamically fitting an insole to a patient, the apparatus comprising: a first fitting panel, comprising: a virtual model of desired strains on the plantar surface of a foot; a plurality of fitting units deployed on the first panel, each fitting unit comprising: (a) a strain sensor, for measuring the strain of the foot on the fitting unit; and (b) an elevating unit, for elevating the top point of the fitting unit to a desired point; a processing unit, for instructing the elevating unit to adjust the elevation of the top point of the fitting unit towards a position wherein the strain of the foot, as measured by the strain sensor, corresponds to the strain of the virtual model.
US08192373B2 Medical guide wire and process for production thereof
A medical guide wire (1) is made in which at least a fluororesin coating layer (13) is formed on the surface of a metal wire (11), wherein particulate matter is present in the fluororesin coating layer (13), and the fluororesin coating layer covers the particulate matter and at least some of the particulate matter is formed in surface protrusion-shaped projections (14). It is thus possible to provide a medical guide wire that is inexpensive to manufacture and whose strength is unaffected and frictional resistance is low, and manufacturing method for the same.
US08192372B2 Test media cassette for bodily fluid testing device
A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.
US08192368B2 Pressure sensing catheter
This invention provides a pressure sensing catheter, and method for using the same, which eliminates the practitioners' need to fill the catheter with fluid manually prior to insertion, and thereby increases the accuracy and ease of the overall pressure-sensing procedure. The illustrative catheter includes, in its proximal end, a transducer base or housing that is permanently attached to the catheter shaft. The base includes, inserted thereinto, one or more miniaturized pressure transducer assemblies, which are in fluid communication with corresponding pressure lumens that extend down the shaft and are in communication with one or more predetermined balloons by discrete channels or ports, which provide a fluid passage between the interior space of the balloon and the corresponding pressure lumen. The integral assembly includes a predetermined, previously installed charge of fluid that extends from the transducer, through the corresponding pressure lumen and into the interior volume of the sensing balloon. The charge of fluid has been made free of any air bubbles at the point of manufacture, and is delivered fully charged, so that maximum sensing accuracy and minimum setup time are achieved. In alternate embodiments the catheter can include a fluid infusion/flushing lumen and port interconnected to a proximal fluid connection.
US08192367B2 Method and apparatus for monitoring respiration
A device for monitoring respiration comprises a duct, a flow restricting element in the duct, and a pressure sensor arranged in the duct. The pressure sensor measures a pressure drop across the flow restricting element as a pressure difference between a pressure at a location in the duct on a first side of the flow restricting element and a substantially constant pressure on a second side of the flow restricting element opposite the first side.
US08192362B2 Methods of monitoring cellular death using low frequency ultrasound
A method of detecting cellular damage within a subject comprises transmitting low frequency ultrasound (20 MHz or below) into a selected site within the subject wherein the selected site has been exposed to a stress capable of causing cellular death at the selected site. At least a portion of ultrasound backscattered from the ultrasound transmitted into the selected site is received. The received backscattered ultrasound is compared to a control backscatter measurement. An increase or a decrease in intensity or spectral slope of the received backscattered ultrasound when compared to the control backscatter measurement indicates cellular death or damage at the selected site within the subject.
US08192358B2 Device and method for use in surgery
The present invention is concerned with a device and method for use in surgery, in particular hand assisted laparascopic surgery, the device comprising a flexible sleeve about one end of which is located a plurality of inflatable balloons, such that the sleeve may be located about a surgeon's forearm, with the balloons thus circumscribing the surgeon's wrist, the balloons being inflated once the surgeon's hand and wrist have been inserted into a surgical cavity, in order to distend the surgical cavity, thereby creating a space within which the surgical procedure may be performed.
US08192357B2 Surgical access system and related methods
A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
US08192354B2 Endoscope inserted-shape detecting apparatus
An endoscope inserted-shape detecting apparatus 8 includes a sense coil unit 23 in which multiple sense coil groups of sense coil groups 23A to 23I for detecting magnetic fields generated by multiple source coils 21 in an inserted-shape detecting probe 6 are placed as a part of the endoscope inserted-shape detecting apparatus 8, a signal detecting section 33, a source coil position analyzing section 35 and a signal control section 37 that selects a magnetic-field detecting element to be used for detection of a magnetic field signal based on the magnetic field generated by each of the source coils 21 from the sense coil groups 23A to 23I in a control section based on positional information signals outputted from the source coil position analyzing section 35.
US08192350B2 Methods and devices for measuring impedance in a gastric restriction system
Methods and devices are provided for gathering impedance data related to implantable restriction devices. In general, the methods and devices can enable patients, health care providers, and others to use gathered data as a feedback mechanism to non-invasively monitor efficacy of an implantable restriction device in a patient and to identify, modify, and/or prescribe a treatment plan for the patient considering the gathered data. Impedance data can be gathered and analyzed for tissue proximate to the restriction device, e.g., a fat pad between a gastric band and the patient's stomach. Electrodes in contact with the tissue can measure an impedance of the tissue, with the impedance between the electrodes changing as the tissue reduces in size (e.g., as fat cells shrink) and/or changes configuration.
US08192348B2 Engineered blood vessels
The present invention relates to engineered blood vessels and methods of making such vessels using matrices comprising endothelial and smooth muscle cells, or cells capable of differentiating into endothelial and smooth muscle cell lineages (e.g., stem cells, or the progenitors thereof).
US08192343B2 Continuous flow ultra-centrifugation systems
A continuous flow centrifuge system is provided. The system includes a rotor, a stator, a stator housing, upper and lower bearing plates, upper and lower bearings, first and second snap rings, and lip seal. The upper bearing rotatably secures a shaft of the rotor in the upper bearing plate. The first snap ring secures the upper bearing to the rotor shaft. The lip seal is over the upper bearing and forms a rotatable seal with the upper bearing plate. The second snap ring secures the lip seal to an inner diameter of the upper bearing plate. The upper and lower bearing plates are secured to the stator housing so that the rotor is operatively aligned with the stator.
US08192342B2 Separator having a liquid outlet including a throttling device
A separator having a conical separator drum mounted rotatably at only one of its axial ends and having a vertical axis of rotation. The drum includes a rotary spindle for driving the separator drum. The separator includes an inflow pipe for a product to be processed and at least two liquid outlets. The first liquid outlet is for a lighter phase and the second liquid outlet is for a heavier phase. The first liquid outlet includes a stripping disk. Further included is a solids discharge port and a separation plate stack in the separator drum. The second liquid outlet is followed outside the drum by a settable throttle device having an annular disk for displacing a liquid radius of the heavier phase by a throttling in an outflow cross section for the heavier phase.
US08192341B2 Pallet and three-dimensional support structure
A three-dimensional support structure is provided and includes a single sheet of material that is folded into a repeating pattern of cells. Each of the cells is formed by first and second spaced-apart endwalls and first and second sloped sidewalls spanning between the endwalls. Each endwall comprises two plies of material while each sidewall comprises a single ply of material. The first and second sidewalls are adjoined at a folded edge. The cells are aligned such that the first endwall of one cell from the repeating pattern abuts the second endwall of an adjacent cell of the repeating pattern to form a four-ply wall of the material. A first liner may be attached to a first side of the folded material and a second liner may be attached to a second side of the folded material.
US08192339B2 Developing roller, manufacturing method thereof, developing apparatus and image forming apparatus
A developing roller on a circumferential surface of which toner is held is provided. In the developing roller, intersecting first and second grooves are formed. Protrusion portions are disposed in areas surrounded by the first and second grooves. The protrusion portions have minute projections.
US08192336B2 Compressive device and carrying compartment for use during exercise
A compressive device and carrying compartment for focusing a compressive force at the general lateral areas of a human waist, and securing at least one object in a generally fixed position relative to the waist, includes a longitudinally elastic belt having lateral area engaging pads, and further including a bag defining an interior space and laterally apposite slot openings, wherein the bag and belt are cooperatively configured such that the belt passes within the space and the compressive force also works to biasly retain the objects in the fixed position.
US08192335B2 Strength and conditioning device and method of conditioning
A strength and conditioning device and method of conditioning. A conditioning device for a sport using a hand held implement having a grip portion comprises a handle shaped like the grip portion, the handle having a first end and a second end. A weight is positioned on the second end such that a center of mass for the conditioning device is less than about 13 inches from the first end of the handle. A bias assembly is removably attached to the weight such that the bias assembly resists movement of the weight during at least some motion of the handle.
US08192329B2 Exercise aiding apparatus
Exercise aiding apparatus includes a step 2 that a user puts a user's foot on, and a step drive means 5 that causes the step to perform movement including turning motion so that exercise is performed with respect to the foot put on the step. The apparatus includes a lock means 6 that fixes the step by engagement with the step except when the step drive means 5 drives the step. When the step is not driven, the step is fixed. The step is prevented from moving inadvertently at getting on and off, thereby ensuring safe getting on and off.
US08192327B2 Methods and systems for assisted direct start control
Methods and systems are provided for controlling a vehicle engine coupled to a stepped-gear-ratio transmission. One example method comprises, in response to a first vehicle moving condition, shutting down the engine and at least partially disengaging the transmission while the vehicle is moving; and during a subsequent restart, while the vehicle is moving, starting the engine using starter motor assistance and adjusting a degree of engagement of a transmission clutch to adjust a torque transmitted to a wheel of the vehicle.
US08192320B2 Multi-speed transaxle
A front wheel drive transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes a sun gear member, a planet carrier member, and a ring gear member. The torque transmitting devices include clutches and a brake arranged within a transmission housing.
US08192319B2 Gear unit and use of the same
The gear unit for use with a manually adjustable electric component has a manually operable adjusting shaft and a reduction gear including a rotatable ball cage and a plurality of balls as well as a race ring element having a spring and retaining portion that encircles the race ring externally. Such a gear unit allows greatly reduced dimensions and furthermore offers a considerable dielectric strength.
US08192311B2 Sport ball with a textile restriction structure
A sport ball may include a casing, a restriction structure, and a bladder. The casing forms at least a portion of an exterior surface of the ball. The restriction structure is located within the casing and includes a textile element having a seamless portion with a non-planar configuration. The bladder is also located within the casing. The textile element may be a knitted fabric. Although the restriction structure may be seamless, the restriction structure may also include at most one seam or multiple seams that joins edges of the textile element. In addition, the seamless portion of the textile element may cover at least thirty percent or more of the surface of the bladder.
US08192310B2 Expandable blunt arrow point apparatus and methods
An arrow point includes a base portion, a tip portion, and a plurality of extension members. The plurality of extension members each have a distal end, a proximal end, and a blunt surface. The proximal end of the extension members is pivotally mounted to the base portion. The extension members are movable upon proximal movement of the tip portion between a retracted position wherein the blunt surface is unexposed, and an extended position wherein the blunt surface is exposed and facing in a generally distal direction.
US08192304B2 Golf club head
An exemplary golf club head having additional discretionary mass may be realized by utilizing light-weight materials, an favorable average crown height, and/or articulation points. By using a preferred break length, the additional discretionary mass may be placed low and deep in the club head to improve the location of the center of gravity as well as the inertial properties. In one example, the center of gravity may be positioned to substantially align the sweet spot with the face center of the club head.
US08192303B2 Golf club head
A golf club head of this invention includes a head body, a weight member attached to the head body, and a fixing unit to fix the weight member at any one of a plurality of attachment positions of the head body. The plurality of attachment positions are located on a straight line included in a plane. The plane includes the center-of-gravity position of the head body without the weight member attached thereto and is perpendicular to the toe-and-heel direction of the head body.
US08192297B1 Variable interface putter golf club with attachable device for analyzing golf course conditions and selecting putter face
A variable interface putter golf club includes a golf club having a shaft with a club head affixed to a first end of the shaft that is distil from a second end of the shaft to be gripped by a golfer. A multi-sided rotatable carousel is contained substantially within the club head of the golf club, the multi-sided rotatable carousel having a putter face on a plurality of sides of the multi-sided rotating carousel. The multi-side rotating carousel preferably is shaped as a pentagon with a different putter face on each of the five sides of the pentagon. A device is included for permitting rotation of the multi-sided rotatable carousel for exposing one putter face of the plurality of putter faces at a given time for allowing the golfer to putt with the one putter face so exposed. A securing device, such as a securing screw, is used for preventing unwanted rotation of the multi-sided rotatable carousel so that only one putter face is exposed at a given time and that the selected putter face is secured in place during play. An optional analyzer device is included which aids the golfer in selecting the appropriate putter face for the conditions of a putter green at a given time. The optional analyzer device may also be used for other types of golf clubs and attached to portion of a golf club other than the shaft.
US08192296B2 Gripping system, apparatus, and methods
A gripping system, apparatus, and methods for users with weakened hand strength, or able-bodied users desiring a better grip, involving a mating glove and a grip, handle, or graspable surface of an object. The mating glove covers a person's hand and interfaces and mates with the grip, handle, or graspable surface. The mating glove has a palm side, a dorsal side, and finger compartments. The mating glove includes hook-and-loop fastener material for mating with complementary hook-and-loop fastener material integrated into the grip, handle, or graspable surface. The grip, handle, or graspable surface further includes recesses integrated within the grip or handle for accommodating the hook-and-loop fastener material. The invention also involves a retrofit tape kit for facilitating gripping of any graspable surface.
US08192293B2 Method and system for shot tracking
A method for predicting a golfer's swing speed, wherein the method comprises determining that the golfer is addressing a golf ball to swing a golf club, monitoring a backswing, determining a transition time, monitoring a downswing, determining an impact time, transmitting data for the golfer's swing to a receiver for analysis and generating a golfer's swing speed using a length of a shaft of the golf club.
US08192291B2 Waterslide bowl with troughs
A waterslide bowl has a fixed rider path from entrance to exit. The bowl comprises a trough which is made of a plurality of sets of trough sections, attached together, in which the trough sections of a given set are the same and nest together side-by-side, permitting the rider surface of the bowl to be made from trough sections having a small number of different shapes. This reduces the number of molds that would otherwise be required to make the trough sections. The waterslide bowl may also have two or more separate troughs, nested together, whereby the bowl may be ridden in by multiple riders at the same time, each in his or her own trough.
US08192290B2 Shrink-fit tool unit as well as tool holder and rotary tool to be used for the shrink-fit tool unit
A shrink-fit tool unit increases the transmission force of rotary power and also improves workability when inserting the rotary tool into the tool holder. A tool holder and a rotary tool to be used for the shrink-fit tool unit are also disclosed. Since a first engaging part and a second engaging part are configured to engage with each other simply by inserting a cylindrical terminal area of a rotary tool, typically, a thread forming tap, into a chuck of the tool holder, even when the machining load receiving from a work piece act both in forward and reverse directions relative to the circumferential direction, it is possible to increase the transmission of rotary power.
US08192289B2 System and method for collecting and using player information
A distributed computer system is provided for collecting player information. Further, a scoring system is provided that rates a player based on one or more elements of the collected information. Players may be rated with respect to a number of characteristics. Responsive to a determined rating or score, action may be taken by the distributed system with regard to the player. For instance, the player may be provided a complimentary offer, provided an award, and invitation to come to a gambling location, presented an advertisement, or other action may be performed involving the player. Further, the distributed computer system may permit a player to manage their frequent player accounts and receive complimentary offers based on a set of criteria specified by the player.
US08192288B2 Remote management of a gaming machine through retrieval of an inventory of assets
Systems, apparatus and methods for remote management of a gaming machine are described herein. In some embodiments, an apparatus includes a host platform having a host processor controlled by a host operating system. The host platform has a host storage and a host power state, wherein the host processor is to execute instructions that includes a wagering game. The apparatus also includes a subsystem that is operable independent of the host operating system and the host power state. The subsystem includes a processor that is separate from the host processor. The subsystem also includes a nonvolatile data store that is separate from the storage of the host platform.
US08192285B2 Method and apparatus for simulating games involving a ball
A sports video game having a new and improved user interface that substantially increases the potential realism of the game uses a handheld controller that is able to sense its own position, orientation and/or motion and is affixed to a ball. The ball can be a model of a football that is provided with a depression that snugly accepts and retains the handheld controller. The handheld controller may sense motion, position and/or orientation of the ball and provide wireless inputs to a video game system. The video game system may process such inputs to provide a simulated sports action game play on a video display.
US08192284B2 Method, storage medium, and apparatus for generating image of virtual space
A method for executing a game having a motif of rolling an object combined with another object with which the object is contacted, on a surface of the object, and growing large like a snowball. The method has: controlling a rotation and a movement of a first object as an operated object, in a virtual space; combining one of a plurality of second objects, with which the operated object is contacted, around a contact position of the operated object, at which the operated object is contacted with the one of the second objects, when the operated object is contacted with the one of the second objects; and determining the operated object with which the one of the second objects is combined, and the one of the second objects, when the one of the second objects is combined with the operated object, as an operated object, newly.
US08192283B2 Networked gaming system including a live floor view module
A networked gaming system includes one or more gaming machines connected to a network, a network-connected user station having a user interface and a display. The networked gaming system further includes a host computer system having an environment module enabled to capture, analyze, and present both historical data stored in at least one data storage device and real-time gaming data from the gaming machines in accordance with one or more requests from the user station.
US08192281B2 Simulated reel imperfections
Described herein is a gaming machine configured to output video data that simulates mechanical reels in a traditional mechanical slot machine. Embodiments described herein contribute to the emulation of a mechanical machine by simulating one or more visible mechanical imperfections commonly found in a mechanical reel machine.
US08192277B2 Systems, methods and articles to enhance play at gaming tables with bonuses
Table games are enhanced by awarding chances at a bonus. The changes may be awarded based on one or more factors, for example amount wagered, time spent wagering, average wager, and/or skill level. Bonus related information may be provided to the players as a group, or individually, for example via one or more displays. A bonus pool may be formed from all or part of a separate bonus wager and/or part of a conventional wager on the outcome of a game being played at the gaming table.
US08192270B2 Bingo game, method, and elimination tournament
A Bingo game, method, and elimination tournament is provided. In one embodiment, the present invention may take the form of a Bingo elimination tournament played by players wagering on respective networked gaming machines in a casino environment. The Bingo elimination tournament may include a plurality of successive Bingo games (rounds) carried out according to standard Bingo methodology, including randomly-drawn numbers being called out, and players' respective Bingo cards being updated (e.g. marked) accordingly, perhaps along with one or more computer-player cards. After each tournament round, among the cards that have not achieved a Bingo during that round, the card or cards having the fewest number of matched numbers are preferably eliminated. Successive rounds are played, often resulting in a single winner of the tournament. Various wagering options are provided for added excitement and enjoyment.
US08192269B2 System and method for operating on-line governmental lottery games
A method for facilitating governmental lottery play over an electronic network includes receiving a request for mobile player terminal location information from an agent server, acquiring location information based upon distances between the mobile player terminal and a plurality of transmitters with known locations, transmitting the acquired location information to the agent server, determining whether the mobile player terminal is located within a lottery jurisdiction based on the transmitted location information, and processing the purchase of a lottery ticket when the location of the mobile player terminal is determined to be located within the lottery jurisdiction.
US08192267B2 Shared game play on gaming device
Embodiments of the present concept provide an electronic gaming device that facilitates wagering by multiple players on a single gaming device. Also provided is a method of sharing game play on such a gaming device, where the method includes receiving a wager from a first player at a first gaming station, receiving a wager from a second player at a second gaming station, initiating a gaming event that is displayed at the first and second gaming stations, and awarding prizes associated with gaming outcomes displayed at the first and second gaming stations.
US08192265B2 Game system
The game system comprises a code reading means for reading a code recorded in a card, a computer program executing means for executing a game in which characters compute, and a display screen for displaying an image generated by the computer program. The game system further comprises a character generating means which, corresponding to a first code read by the reading means, generates a character indicated on the first card with the first code recorded in, a move generating means which, corresponding to a second code, sets a move indicated on the second card with the second cord recorded in, and a display means for displays on the display screen an image in which the character generated by the character generating means executes the move set by the move setting means to fight. When a first special code recorded in a first special card without a character indicated on is read by the code reading means, the character generating means generates a preset character, and the move setting means sets a move which is different from a move indicated on the second cord with the second code recorded in. The game system can amusingly make full use of the characteristics of the game cards.
US08192257B2 Method of manufacture of constant groove depth pads
Processing pads for mechanical and/or chemical-mechanical planarization or polishing of substrates in the fabrication of microelectronic devices, methods for making the pads, and methods, apparatus, and systems that utilize and incorporate the processing pads are provided. The processing pads include grooves or other openings in the abrading surface containing a solid or partially solid fill material that can be selectively removed as desired to maintain the fill at an about constant or set distance from the abrading surface of the pad and an about constant depth of the pad openings for multiple processing and conditioning applications over the life of the pad.
US08192254B2 Sander with a balance means
A sander according to the present invention comprising a housing, a motor and a transmission mounted within the housing, a sanding plate mounted below the housing, a battery pack mounted at the rear end of the housing and a balancer mounted on either the housing or the sanding plate. The balancer includes a balance element disposed in the front part of the sander. The balance element is balanced with the battery pack, which solves the balance problem of the DC sanders known in the prior art while still providing a battery pack that can satisfy the power requirements of the sander.
US08192251B2 Pressure control system of wafer polishing apparatus
A pressure control system of a wafer polishing apparatus includes a main input air pressure regulator, an air branch conduit, a plurality of first pipes, a plurality of auxiliary air pressure regulators, a plurality of second pipes, and a plurality of air pressure controlling devices. The air branch conduit is connected with the main input air pressure regulator. The first pipes are connected between the air branch conduit and the auxiliary air pressure regulators. The second pipes are connected between the auxiliary air pressure regulators and the air pressure controlling devices. Accordingly, the air pressure controlling devices can control the pressure outputted from a polishing head of the wafer polishing apparatus to a surface of a wafer.
US08192250B2 Abrasive article
An abrasive article is disclosed that is suitable for cleaning, sanding, scraping, or other such process of removing an outer layer or adherent matter. The abrasive article includes a plurality of abrasive particles at least partially embedded in a frozen liquid.
US08192245B2 Vent seal for inflatable devices
A seal for vent openings of inflatable structures is provided that includes an interior and an exterior component that can be affixed to each other and to the inflatable structure and allows for higher pressures to be maintained within the inflatable structure.