最新美国发明专利第2012-05-29期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08188747B2	Method for timestamping boring tool locations A boring tool is moved through the ground within a given region along a particular path. The boring tool is moved in cooperation with moving a portable locator to establish a series of boring tool locations of the boring tool on the particular path. As at least one location of the series of locations is established, the location and a time stamp are electronically recorded to designate at least a time at which the location was recorded.
US08188743B2	Magnetic resonance imaging apparatus and control method of magnetic resonance imaging apparatus According to a Magnetic Resonance Imaging (MRI) apparatus, each of buttons provided in a plurality of sections included in a receiving coil receives from an operator a selecting operation of selecting a section in which the button itself is provided. A control unit of a computer system moves a table on which a subject is placed such that the center of the section selected by receiving the selecting operation via the button is positioned at the center of a magnetic field.
US08188741B2	Magnetic resonance imaging apparatus and chiller By using a temperature monitor, a coil-dedicated chiller measures an amount of change in temperature of cooling water flowing out from a cooling pipe of a gradient magnetic field, determines an amount of change in temperature of cooling water to be flowed into the cooling pipe in accordance with the measured amount of change in temperature of the cooling water; and changes the temperature of cooling water to be flowed into the cooling pipe of the gradient magnetic field based on the determined amount of change in temperature.
US08188740B2	Magnetic resonance imaging apparatus The present invention provides a vertical magnetic field MRI apparatus which is capable of speeding up imaging for taking an image of any cross section of a wide area such as a total body, while suppressing increase of the number of channels and maintaining high sensitivity in a deep portion of a subject. A receiver coil unit 500 incorporates a bed coil unit 600 whose longitudinal direction agrees with a body axis direction of the test object 103, and an upper coil unit 700 which is detachably mounted on the bed coil unit 600. The bed coil unit 600 is provided with a carrying surface 601 for placing the test object 103 thereon and multiple lower sub-coils arranged in a lower part of the carrying surface 601, and the upper coil unit 700 is provided with multiple upper sub-coils which are connected to the lower sub-coils. The upper sub-coils are separated into two parts; one arranged in a flexible inner support 20-1 covering the installation surface 601 and another arranged in a flexible outer support 20-2 covering the external side of the inner support 20-1. The upper sub-coils and the lower sub-coils are connected by mounting the upper coil unit 700 on the bed coil unit 600, thereby forming the multiple types of sub-coils.
US08188737B2	MRI compatible radio frequency (RF) coil, with each rung of the RF coil containing a plurality of individual parallel wires internally A radio frequency (RF) coil for a magnetic resonance imaging (MRI) system includes a plurality of rungs. Each rung includes a plurality of wires positioned parallel to one another. Each wire has a circular cross section and an insulating material disposed around an outside surface of the wire. Using wires with a circular cross-section reduces the eddy currents produced on a rung. As a result, the amount of eddy current produced heating, vibration and acoustic noise is reduced. The plurality of wires also enables a more uniform current distribution along the width of each rung that in turn produces a more uniform excitation field (B1).
US08188736B2	PET/MR scanners for simultaneous PET and MR imaging In a combined system, a magnetic resonance (MR) scanner includes a magnet (10, 110) configured to generate a static magnetic field (B0) at least in a MR examination region (12) from which MR data are acquired. Radiation detectors (40, 41, 140) are configured to detect gamma rays generated by positron-electron annihilation events in a positron emission tomography (PET) examination region (70). The radiation 5 detectors include electron multiplier elements (60, 160) having a direction of electron acceleration (ae) arranged substantially parallel or anti-parallel with the static magnetic field (B0). In some embodiments, the magnet is an open magnet having first and second spaced apart magnet pole pieces (14, 15) disposed on opposite sides of a magnetic 10 resonance examination region, and the radiation detectors include first and second arrays (40, 41) of radiation detectors disposed with the first and second spaced apart magnet pole pieces.
US08188735B2	Resolution enhanced T1-insensitive steady state imaging (RE-TOSSI) Systems, methods, and other embodiments associated with RE-TOSSI are described. One system embodiment includes an MRI apparatus configured to produce a RE-TOSSI pulse sequence and to acquire T2-weighted images in response to the RE-TOSSI pulse sequence. An example RE-TOSSI pulse sequence includes a TOSSI portion and a non-inverting, non-TOSSI portion.
US08188733B2	Arrangement and method for recognizing and classifying preferably hidden objects in object and/or human traffic An arrangement and method recognizes and classifies preferably hidden objects in object and/or human traffic. Objects relevant to security are recognized, located and tracked through the surroundings thereof in moving object and human traffic isolated in real time. Use is made of a combination of a field generator, the field of which is modified by at least one corresponding object within the scanned space, first sensors which repeatedly record the changes in the field and provide corresponding signals, second sensors which record defined surroundings of the object in real-time with relation to the first sensors and provide corresponding signals and analytical means which correlate and collate the signals from the sensors with each other and which give from the same the shape, spatial position and/or spatial orientation of the object.
US08188730B2	Method and system for inductive proximity sensing that includes mounting effect compensation An inductive proximity sensor and related method for sensing a presence/position of a target, with mounting effect compensation, are disclosed. In at least one embodiment, the method includes providing a proximity sensor having first and second coils that are both at least indirectly in communication with control circuitry. The method also includes receiving respective first and second signals at least indirectly indicative of respective first and second electromagnetic field components respectively experienced by the first coil as influenced both by a target and a structure supporting the sensor and the second coil as influenced by the supporting structure. The method further includes determining by way of the circuitry a third signal based at least in part upon the first signal, as modified based at least in part upon the second signal, whereby the third signal is indicative of the presence or position of the target relative to the sensor.
US08188727B2	Hub mountable speed sensing device A hub mountable speed sensing device comprising a housing, a metallic tubular insert adapted to be press-fitted with respect to the housing, a stationary speed sensing probe comprising a magnetic conversion device having a bias magnet and adapted to be inserted into the housing in close proximity to the rotating member having sensing teeth along its axis made of ferrous material, a locking arrangement provided to prevent the detection probe from dislodging from the housing, and wherein the bias magnet is adapted to generate magnetic flux which is interrupted by the rotor tooth while rotating the magnetic conversion device providing for speed sensing biased on the change in flux density.
US08188718B2	Method and apparatus for a remote battery charger with a self contained power source A battery charger with a self-contained power source which provides a current charging signal at or near the resonant frequency of the battery to be charged when no other power supply is readily available. A storage energy device, for example a battery, delivers a current charging signal modulated at or near the resonant frequency of a load, or stores energy from a source.
US08188716B2	Lithium-sulphur battery with a high specific energy and a method of operating same A multi-electrode lithium-sulphur cell or battery including for example a negative electrode made of metal lithium, lithium alloys or lithium-absorbing materials; at least first and second distinct positive electrodes or groups of positive electrodes; and an electrolyte that is a solution of one or several salts in one or several solvents disposed between the negative and positive electrodes. The first positive electrode or group of positive electrodes is configured for charging, and the second positive electrode or group of positive electrodes is configured for discharging. The cell or battery has a high specific energy. Other embodiments of the present invention may include other structures and properties.
US08188713B2	Fixed charging socket for digital devices An embedded charging socket includes a case and an AC-to-DC circuit. The case is combined with a positioning slot of a panel, so as to be fixed on a specific position, for example, a wall surface, through the panel. The case has an AC input end disposed on one side for inputting an AC voltage, and has at least one universal serial bus (USB) slot disposed on the other side. Further, the AC-to-DC circuit is disposed inside the case, and has two sides respectively electrically connected to the AC input end and the USB slot, for converting the AC voltage to a DC voltage, then outputting the DC voltage through the USB slot, and charging an electric apparatus after an USB connector is inserted.
US08188709B2	Power transmission control device, power transmitting device, non-contact power transmitting system, and electronic instrument A power transmission control device used for a non-contact power transmission system includes an operation mode switching terminal that receives an operation mode switch control signal that switches a mode between an automatic mode and a switch mode, a power transmitting device starting normal power transmission in the automatic mode after installation of a power-receiving-side instrument that includes a power receiving device in an area in which power transmitted via non-contact power transmission can be received has been automatically detected, the normal power transmission supplying power to a load of the power-receiving-side instrument, and the power transmitting device starting the normal power transmission in the switch mode after an operation trigger switch has been turned ON, an operation trigger terminal that receives an operation trigger signal that occurs due to an operation of the operation trigger switch, and a power-transmitting-side control circuit that controls power transmission to the power receiving device and changes an operation mode of the power transmitting device based on the operation mode switch control signal.
US08188706B2	Power management unit with battery detection controller and switchable regulator block According to one exemplary embodiment, a power management unit residing in an electronic device includes a battery detection controller coupled to a battery charger and a regulator block, where the regulator block is capable of providing power to the electronic device. The battery detection controller is configured to turn off the regulator block when the battery charger is coupled to an external power source and is not coupled to a battery of the electronic device. The battery detection controller can be further configured to turn on the regulator block when the battery charger is coupled to the external power source and is coupled to the battery if the battery has a battery voltage greater than a threshold voltage.
US08188705B2	Charge method and device of battery for electric motor vehicle The present invention is a charge method of a battery for an electric motor vehicle, in which a battery is charged by an outside electric source. A residual charge quantity of the battery is detected before charging. A maximum-quantity charge time Ttotal which is required for the residual charge quantity of the battery becoming the maximum quantity is calculated based on detection result. A driving-start time tds of the electric motor vehicle is estimated. A first charge is executed so as to be started from a driving stop of the electric motor vehicle, continued for a period of time which is shorter than the maximum-quantity charge time Ttotal, and completed before the driving-start time tds. A second charge is executed so as to be started after the first charge is completed and completed at the driving-start time tds.
US08188702B2	Rotating electrical machine control system and vehicle drive system A rotating electrical machine control system includes a frequency converting portion that is interposed between a rotating electrical machine for driving a vehicle and a DC power source for supplying electric power to the rotating electrical machine, and that converts an output of the DC power source to an AC output at least during a powering operation of the rotating electrical machine; a voltage converting portion that is interposed between the DC power source and the frequency converting portion, and that boosts the output of the DC power source based on a boost command value which is set according to a target torque and a rotational speed of the rotating electrical machine; and a control portion for controlling the frequency converting portion and the voltage converting portion.
US08188697B2	Apparatus and method for driving a motor A sampling circuit samples, while running a motor at a predetermined rotational speed, over a predetermined period a back electro-motive force induced at one end of at least one phase coil, with one end of each phase coil of the motor being brought to a high impedance. A waveform data generating circuit holds as waveform data SIN the back electro-motive force beforehand sampled by the sampling circuit. A PWM signal generating circuit sequentially reads the waveform data SIN from the waveform data generating circuit to generate a PWM signal Spwm, the pulse width of which is modulated.
US08188693B2	DC bus boost method and system for regenerative brake Embodiments of the present invention provide novel techniques for using a switched converter to provide for three-phase alternating current (AC) rectification, regenerative braking, and direct current (DC) voltage boosting. In particular, one of the three legs of the switched converter is controlled with a set of pulse width modulation (PWM) control signals so that the input AC phase having the highest voltage is rectified and one of the switches in the two other legs is turned on to allow for added voltage. This switching activity allows for voltage from multiple AC line mains to be combined, resulting in an overall boost of the DC voltage of the rectifier. The DC voltage boost can then be applied to the common DC bus in order to ameliorate voltage sags, help with motor starts, and increase the ride-through capability of the motor.
US08188692B2	Propulsion system A propulsion system is provided. The system includes: a first propulsion vehicle unit including a first tractive bank having at least one traction motor; a second propulsion vehicle unit including: a second tractive bank having at least one traction motor, a contactor electrically coupling the first propulsion vehicle unit and the second propulsion vehicle unit, and an electrical power modulation device coupled between the first tractive bank and the second tractive bank, the electrical power modulation device having an electrical current threshold that causes the electrical power modulation device to transition to an open state to reduce or prevent transfer of electrical power between the first propulsion unit and the second propulsion unit in response to an electrical current at the electrical power modulation device being above the electrical current threshold.
US08188690B2	Magnetically powered reciprocating engine and electromagnet control system The instant invention provides a magnetically controlled reciprocating engine having a unique electromagnet control system. The engine is constructed and arranged to operate from a stored power source such as batteries to provide extended run times by controlling the power supplied to the electromagnets in a manner that controls heat generation within the electromagnetic coils, thereby increasing coil life. The control system is also capable of controlling engine speed and/or torque outputs to make the engine versatile for a wide variety of uses. The system is constructed and arranged to be utilized on new or pre-existing engines of various configurations and may be utilized in other industries or devices that benefit from the use of electromagnets.
US08188688B2	Magnetic field control method and apparatus used in conjunction with a charged particle cancer therapy system The invention comprises a charged particle beam acceleration, extraction, and/or targeting method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors. Novel design features of a synchrotron are described. Particularly, turning magnets, edge focusing magnets, concentrating magnetic field magnets, winding and control coils, flat surface incident magnetic field surfaces, and extraction elements are described that minimize the overall size of the synchrotron, provide a tightly controlled proton beam, directly reduce the size of required magnetic fields, directly reduces required operating power, and allow continual acceleration of protons in a synchrotron even during a process of extracting protons from the synchrotron.
US08188685B1	Light-generating system A light-generating system including a LED load array having a number of light-emitting diodes, and a heat sink on which the LED load array is mounted. The system also includes a power control unit electrically connected to the power source and the LED load array, for converting input electrical power to output electrical power and controlling voltage and current of the output electrical power provided to the LED load array, and a temperature detector subassembly adapted for sensing a heat sink temperature of the heat sink. The temperature detector subassembly monitors the heat sink temperature and transmits a control signal to the power control unit upon determining that the heat sink temperature differs from a preselected temperature by more than a preselected minimum difference. Upon receipt of the control signal, the power control unit changes the voltage of the output electrical power accordingly.
US08188682B2	High current fast rise and fall time LED driver The present invention contemplates a variety of improved techniques for the fast switching of current through, among others, LED loads. A current shunting device is utilized to divert current away from a load at high speed when activated, thus enabling the control of the amount current that flows through the load.
US08188679B2	Self-powered LED bypass-switch configuration A LED string is divided into segments that each have a bypass-switch and a driver for the bypass-switch. The driver is powered by a supply voltage locally generated from the forward-voltages of the LEDs of the segment.
US08188678B2	Circuit arrangement for operating at least one semiconductor light source A circuit arrangement for operating at least one semiconductor light source having an input for inputting an input voltage, an output for outputting an output voltage to the semiconductor light source, wherein the main current path of the circuit arrangement lies between the two input terminals, and comprises a series circuit formed by a switch, an inductance and a back-to-back connection of a first diode or light emitting diode and the at least one semiconductor light source, wherein a first storage capacitor is arranged in parallel with the at least one semiconductor light source, and a second diode is arranged in series with this parallel connection.
US08188676B2	Systems and methods for driving light-emitting diodes At least some embodiments include a LED driver system. The system includes multiple branches of series-coupled LEDs, multiple current sources, and control logic. Each of the current sources is coupled to a separate branch of series-coupled LEDs. The control logic is coupled to the current sources, and is configured to regulate current through each branch based at least in part on a feedback voltage measured at a node in one of the branches.
US08188672B2	High-pressure discharge lamp system and projector using the same A high-pressure discharge lamp system has a high-pressure mercury lamp 4 and a lighting circuit 3 that operates the lamp 4. The lamp 4 includes an envelope having a light emitting part 6 having a first and a second electrode 10, 11 arranged therein and a first and a second sealing part 7, 8 oppositely extending from the light emitting part 6, and a conductor 20 electrically connected to the second electrode 11. Particularly a portion of the conductor 20 is at least in contact with or in closest proximity to the outer surface of the first sealing part 7 substantially at a single point in an area corresponding to a first metal foil 16 connected to the first electrode 10. The circuit 3 activates the lamp 4 by placing high-frequency voltage at a predetermined frequency within a range of 10 [kHz]-10 [MHz], inclusive, between the electrodes 10, 11.
US08188670B2	Light emitting device and method for driving light emitting device A light emitting device which can emit light of an arbitrary color temperature and a process for producing a light emitting device which can emit light of an arbitrary color temperature are provided. Such a light emitting device includes a first light emitting diode device (2) and a second light emitting diode device (3) which are connected together in parallel, and a power-supply apparatus (4) which is capable of reversing polarity, in which the color temperature of the first light emitting diode device (2) is set to be higher than the color temperature of the second light emitting diode device (3).
US08188668B2	Image display apparatus and method of driving the same An image display apparatus includes a rear plate provided with a plurality of electron-emitting devices, each electron-emitting device emitting electron; a face plate disposed opposite the plurality of electron-emitting devices and provided with a plurality of pixels of phosphor, each pixel of phosphor being irradiated with electrons emitted from corresponding ones of the electron-emitting devices to generate light; and a driver for scanning the plurality of electron-emitting devices for emitting electron from the plurality of electron-emitting devices. The phosphor has luminescence center of allowed transition type material, and the driver scans the plurality of electron-emitting devices so that maximum of charge density dosed in one pixel phosphor, during one scanning period, is equal to or larger than 3×10−8 C/cm2.
US08188664B1	Compact high intensity discharge lamp with textured outer envelope A compact mercury-free high intensity discharge (HID) lamp particularly suitable for automotive headlamp application has a pair of spaced and opposing electrodes sealed in a transparent enclosure defining an arc chamber. An outer transparent envelope has a first and second textured light scattering stripe on its interior surface on substantially opposite sides thereof extending continuously from one electrode to the other. The stripes widen the cross-sectional luminance distribution of the arc discharge image and make the image of the arc straighter while keeping light scattering losses at minimum so that the reduced arc peak luminance is still at the desired level. In other versions, a plurality of textured light scattering stripes of smaller widths are employed to replace a single wider light scattering stripe.
US08188662B2	Plasma lamp having tunable frequency dielectric waveguide with stabilized permittivity An electrodeless plasma lamp and method of generating light are described. The lamp may comprise a lamp body, a source of radio frequency (RF) power and a bulb. The lamp body may comprise a solid dielectric material and at least one conductive element within the solid dielectric material. The source of RF power is configured to provide RF power and an RF feed configured to radiate the RF power from the RF source into the lamp body. One or more tuning mechanisms allow tuning of the lamp body to a given resonant frequency. The bulb is positioned proximate the lamp body and contains a fill that forms a plasma when the RF power is coupled to the fill from the lamp body. The at least one conductive element is configured to concentrate an electric field proximate the bulb.
US08188659B2	Composition for forming a multi-layered electrode and plasma display panel manufactured with the same An electrode composition includes a metal in an amount of about 52% to about 62% by weight of the composition, a glass insulation material in an amount of about 5% to about 7% by weight of the composition, a coloring agent in an amount of about 3% to about 9% by weight of the composition, and a vehicle.
US08188657B2	Illuminating lamp and method of making same A technique for mounting single or double ended quartz halogen or HID burner on threaded incandescent lamp base facilitating high volume production and use of existing manufacturing equipment. The pinched end portion of the burner is received in a slot formed in an end of a ceramic tubelet and secured therein and supported thereon by cementing or elastic adhesive bond material. The tubelet has its opposite end secured over a reduced diameter portion of a stem extending from the incandescent lamp base. An outer bulb of translucent or transparent material is received over the base-burner sub-assembly and the bulb secured to the base.
US08188655B2	Light-emitting device and electronic devices The present invention provides a lightweight, thin light-emitting device having a new structure which has a plurality of display screens. Further, the invention provides a dual emission type display device which can perform a pure black display and can achieve high contrast. According to the invention, at least, both electrodes of a light-emitting element (an anode and a cathode of a light-emitting element) are highly light-transmitting at the same level, and a polarizing plate or a circularly polarizing plate is provided, thereby conducting a pure black display that is a state of no light-emission and enhancing the contrast. Moreover, unevenness of color tones in displays of the both sides, which is a problem of a full-color dual emission type display device structure, can be solved according to the invention.
US08188654B2	AC driven light emitting device An alternating current (AC) driven light emitting device includes a substrate, K number of first light emitting diode (LED) cells arranged in a row on a top surface of the substrate, where K is an integer satisfying K≧3, K number of second LED cells arranged in a row parallel to the row of the first LED cells on the top surface of the substrate, and (K−1) number of third LED cells arranged in a row between the respective rows of the first and second LED cells on the top surface of the substrate. The AC driven light emitting device has a connection structure between LED cells to be operable at an AC.
US08188650B2	Method for preparing multilayer of nanocrystals, and organic-inorganic hybrid electroluminescence device comprising multilayer of nanocrystals prepared by the method A method for preparing a multilayer of nanocrystals. The method includes the steps of (i) coating nanocrystals surface-coordinated by a photosensitive compound, or a mixed solution of a photosensitive compound and nanocrystals surface-coordinated by a material miscible with the photosensitive compound, on a substrate, drying the coated substrate, and exposing the dried substrate to UV light to form a first monolayer of nanocrystals, and (ii) repeating the procedure of step (i) to form one or more monolayers of nanocrystals on the first monolayer of nanocrystals. Further, an organic-inorganic hybrid electroluminescence device using a multilayer of nanocrystals prepared by the method as a luminescent layer. The luminescent efficiency and luminescence intensity of the electroluminescence device can be enhanced, and the electrical properties of the electroluminescence device can be controlled by the use of the multilayer of nanocrystals as a luminescent layer.
US08188645B2	Hot cathode and ion source including the same A hot cathode includes: a hollow external conductor; a hollow internal conductor which is placed coaxially inside the external conductor; and a connection conductor which electrically connects tip end portions of the conductors. A heating current is folded back through the connection conductor to flow in opposite directions in the external conductor and the internal conductor.
US08188642B2	Spark plug for internal combustion engine A spark plug 1 includes an insulator 2, a metal shell 3, a center electrode 5 and a ground electrode 27. A spark discharge gap 33 is formed between a front end portion 28 of the center electrode 5 and the ground electrode 27. The metal shell 3 has a through hole 29 therein and a metal convex portion 21 inwardly radially projecting in the through hole 29. The metal convex portion 21 includes a convex rearward face 30, a convex inner circumferential face 31 and a convex forward face 32. The through hole 29 has an inner diameter A (mm) at a front end side inner circumferential face 40, which is located at the front end side with respect to the convex forward face 32. The insulator 2 is inserted in the through hole 29 and has a first insulator taper portion 14, a second insulator taper portion 36 and a base 37 between the taper portions. The present invention satisfies the following representations: G≦(A−B)/2; A≧7.3; and 2≦XX≦4, where “B” (mm) is an outer diameter of a border K between an insulator front end portion 38 and the second insulator taper portion 36, where “G” (mm) is a distance of a spark discharge gap 33, and where “XX” (mm) is a length from a very-end portion FF of the convex inner circumferential face 31 to the border K in the axial C1 direction.
US08188638B2	Cooling acoustic transducer with heat pipes A transducer with a closed heat pipe is provided with a hot surface and a cold surface. The hot surface is in contact with the transducer interior and the cold surface is in contact with a cooler contact area. A fluid is used in the pipe which boils at the temperature of the hot surface and condenses at the temperature of the cold surface. A wick inside the heat pipe facilities the return by capillary action of the condensed fluid to the hot end. The heat pipe can be evacuated to adjust the boiling temperature of the fluid. A variant involves drilling additional holes into ceramic rings and inserting heat pipes. Increasing the heat pipe length into the tail mass and the piston increases the cool region for the fluid to condense; thereby improving the performance of the transducer.
US08188631B2	Rotor of reduced weight for an electric machine A rotor for an electrical machine includes a first shaft part and a second shaft part, which is arranged separately from the first shaft part. A first supporting element is connected in a manner fixed against rotation to the first shaft part, and a second supporting element is connected in a manner fixed against rotation to the second shaft part. The rotor has a yoke which connects the first supporting element to the second supporting element and includes a plurality of laminates arranged one behind the other, and which has cutouts extending in the direction of the axis of rotation in the interior of the yoke, and permanent magnets arranged in the cutouts. The yoke has holes extending in the direction of the axis of rotation, with tensioning pins extending through the holes in the yoke to brace the laminates.
US08188630B2	Magnetic amplifier A Magnetic amplifier has a main disc having a plurality of permanent magnets embedded therein; an electric generator; a main disc shaft connected and passing through the center of the main disc and mechanically connected at an end thereof to the electric generator; at least one electric motor; an electric motor shaft mechanically connected to each of the at least one electric motor; an oblong permanent magnet attached to a distal end of each electric motor shaft opposite the end attached to the electric motor, wherein each of the oblong magnets are positioned in close proximity to the radial edge of the main disc to thereby interact with the permanent magnets of the main disc, wherein when the at least one electric motor rotates the respective oblong permanent magnets, the main disc is magnetically induced to rotate and thereby create electrical energy within the electric generator.
US08188626B2	Controller-integrated electric rotating machine There is obtained a controller-integrated electric rotating machine that is superior in terms of a cooling effect.In a controller-integrated electric rotating machine provided with a stator 3 configured with an iron core 3B and a stator winding 3A, a rotor 4 having a cooling fan 5, an inverter power circuit 20 that is a control apparatus for applying a stator current to the stator winding 3A, and a bus bar 30 that supplies the inverter power circuit 20 with electric power from a battery, the inverter power circuit 20 includes a power module 21 that has a function of switching the stator current, a heat sink 23 on which the power module 21 is mounted by the intermediary of an insulating layer, and an insulator case 25 that incorporates the power module 21 and holds respective terminals of the power module 21; and the bus bar 30 is connected with terminals 22a, 22b, 22c, and 22d of the inverter power circuit 20 and has a cooling fin 30a.
US08188624B2	Brushless DC motor for fuel pump The present invention is characterized in that it does not require specific fastening tools, which causes breakage or defects, or bonding work, because a brushless DC motor includes an insulator that is inserted in a stator to insulate a coil wound with led magnet wires and has at least one or more locking portions with locking grooves stepped on the inner side along the circumference and an outlet connector that has hooks fitted in the locking protrusions when being assembled with the insulator such that the insulator and the outlet connector are assembled in fitting and locking ways in assembling.
US08188621B2	Apparatus and method for restricting power delivery An apparatus and method for restricting operation of a power delivery system are disclosed. In at least some embodiments, the apparatus includes a first input terminal at which is received a first command signal, and a second input terminal at which is received an additional signal. The apparatus further includes an output terminal at which is provided a control signal, and a circuit that generates the control signal based at least indirectly upon the first command and additional signals. The control signal generated by the circuit is configured to cause the power delivery system to not deliver at least one type of power when the first command signal indicates a command to do so, if the additional signal indicates an acceptability status. In some embodiments, the power delivery system is an isolation system (e.g., safety isolation system) as are employed in industrial environments, and the apparatus is a permissive module.
US08188618B2	Power supply circuit A power supply circuit includes a first DC-DC converter, a second DC-DC converter, a voltage detection circuit, a delay circuit and a switch. The second DC-DC converter converts an output voltage of the first DC-DC converter into a second voltage and outputs the second voltage. The voltage detection circuit outputs a detection signal when an output voltage of the first DC-DC converter becomes a threshold voltage or more. The delay circuit outputs a delayed detection signal with a delay of a predetermined time from a point of time that the detection signal outputted from the voltage detection circuit is inputted to the delay circuit. The switch is connected between the first DC-DC converter and an output terminal. The second DC-DC converter starts an operation in response to the delayed detection signal outputted from the delay circuit. The switch is closed in response to an output from the second DC-DC converter.
US08188617B2	Current balancing apparatus, current balancing method, and power supply apparatus A current balancing apparatus includes a first transformer having a first primary winding and a first secondary winding electromagnetically coupled with the first primary winding, the first primary winding having a first end connected to a first load that passes a first current; a second transformer having a second primary winding and a second secondary winding electromagnetically coupled with the second primary winding, the second primary winding having a first end connected to a second load that passes a second current having an AC component substantially having a 180-degree phase difference with respect to the first current; and a series circuit including the first secondary winding, the second secondary winding, and a current smoother, to balance the first current and second current with each other.
US08188615B2	Integrated circuit adapted to be selectively AC or DC coupled An integrated circuit is adapted to be selectively AC or DC coupled to an external device at a coupling point. The integrated circuit includes a first connector connected to the coupling point by way of a coupling capacitor for AC coupling, a second connector connected to the coupling point for DC coupling, and a switch to selectively short the first and second connectors and thereby the coupling capacitor, when the integrated circuit is DC coupled to the device. The switch may be a MOSFET bridge comprising a switch control MOSFET interconnected between the first and second connectors, with the switch control MOSFET receiving at its gate a mode status signal for turning on the switch control MOSFET and thereby shorting the MOSFET bridge when the integrated circuit is DC coupled to the external device. The MOSFET bridge also includes a number of dynamically biased nMOSFETs connected in series with the switch control MOSFET in order to protect switch control MOSFET from high external supply voltages, and a number of dynamically biased pMOSFETs connected in parallel with the switch control MOSFET.
US08188612B2	Wind turbine generator and start-up method of the same A start-up method of a wind turbine generator includes a step of increasing a pitch angle of a wind turbine blade from a feather pitch angle to a fine pitch angle. The step of increasing the pitch angle of the wind turbine blade includes steps of: determining based on first to n-th pitch angles (n≧2) greater than the feather pitch angle and smaller than the fine pitch angle and first to n-th rotational speed conditions associated with the first to n-th pitch angles, respectively, whether a control target rotational speed, which is a wind turbine speed or generator speed, satisfies the i-th rotational speed condition when the pitch angle reaches the i-th rotational speed out of the first to n-th pitch angles, the first to n-th pitch angles and the first to n-th rotational speed conditions being stored in a storage unit; decreasing the pitch angle to the (i−1)-th pitch angle or the feather pitch angle in a case that the control target rotational speed does not satisfy the i-th rotational speed condition when the pitch angle reaches the i-th pitch angle; and increasing the pitch angle to the (i+1)-th pitch angle or the fine pitch angle in a case that the control target rotational speed satisfies the i-th rotational speed condition when the pitch angle reaches the i-th pitch angle.
US08188611B2	Flow deflection devices and method for energy capture machines The flow of fluid into energy capture machines is crucial for determining the amount of energy extracted, particularly in the field of renewable energy resources. The current invention describes devices and methods for applying the physics of flow to energy capture machines, most commonly wind and water turbines, by enhancing the flow into the energy capture component by the appropriate placement of various objects called flow deflection devices (FDD). FDDs can make a highly significant improvement in power output.
US08188610B2	Wind turbine having a main power converter and an auxiliary power converter and a method for the control thereof A wind turbine comprising a main generator, a main power converter connected to the main generator and adapted to convert the electrical output power of the main generator to an electrical power to be fed into the utility grid up to a first rated converter output power and an auxiliary power converter connected to the main generator and adapted to convert the electrical output power of the main generator to an electrical power up to a second rated converter output power which is lower than the first rated converter output power is provided. Further, a control architecture for controlling the power balance of a wind turbine and a method for operating a wind turbine are provided.
US08188608B2	Ejector device An ejector device effective to generate a negative pressure by element of compressed air fed to an ejector of the device via a compressed-air duct includes an air suction duct, a pressure sensor and an electrically activatable valve member arranged in the compressed-air duct for regulating the flow of compressed air to the ejector, as well as electrically supplied control electronics (6) adapted to actuate the valve member in response to the pressure in the air suction duct detected by the sensor. The device includes an accumulator by which the control electronics are supplied with electricity, and a generator, which via a charging air duct (9), is in flow communication with the compressed-air duct and is driven by compressed air for generating electrical energy, which is brought into the accumulator for charging the same.
US08188606B2	Solder bump interconnect A semiconductor package includes a device pad on a substrate. A polybenzoxazole (PBO) layer overlies the substrate, and the PBO layer has an opening to expose the device pad. A redistribution layer (RDL) comprises a landing pad, and the RDL is positioned on the PBO layer and conductively coupled to the device pad. A polymer layer is on the RDL, and an under bump metal pad (UBM) is on the landing pad and extends onto a top surface of the polymer layer. The UBM electrically connects to the landing pad through an opening in the polymer layer. A solder bump is secured to the UBM. A shortest distance from a center of the landing pad to an outer edge of the landing pad, and a shortest distance from a center of the UBM to an outer edge of the UBM are in a ratio that ranges from 0.5:1 up to 0.95:1.
US08188605B2	Components joining method and components joining structure To provide a components joining method and a components joining structure which can realize joining of components while securing conduction at a low electrical resistance with high reliability.In a construction in which by using a solder paste containing solder particles 5 in a thermosetting resin 3a, a rigid substrate 1 and a flexible substrate 7 are bonded by the thermosetting resin 3a, and a first terminal 2 and a second terminal 8 are electrically connected by the solder particles 5, a blending ratio of an activator of the thermosetting resin 3a in the solder paste is properly set and oxide film removed portions 2b, 8b, and 5b are partially formed in oxide films 2a, 8a, and 5a of the first terminal 2, the second terminal 8, and the solder particles 5. Thereby, the first terminal 2 and the second terminal 8 are electrically conducted by solder bonding the solder particles 5 to both the first terminal 2 and the second terminal 8 via the oxide film removed portions 2b and 8b, and while fusion of the solder particles 5 with each other is prevented in the thermosetting resin 3a, connection of components at a low electrical resistance is realized with high reliability.
US08188601B2	Semiconductor subassemblies with interconnects and methods for manufacturing the same A semiconductor subassembly is provided for use in a switching module of an inverter circuit for a high power, alternating current motor application. The semiconductor subassembly includes a wafer having first and second opposed metallized faces; a semiconductor switching device electrically coupled to the first metallized face of the wafer and having at least one electrode region; and an interconnect bonded to the semiconductor switching device. The interconnect includes a first metal layer bonded to the at least one electrode region of the semiconductor switching device, a ceramic layer bonded to the first metal layer, the ceramic layer defining a via for accessing the first metal layer, a second metal layer bonded to the ceramic layer, and a conducting substance disposed in the via of the ceramic layer to electrically couple the first metal layer to the second metal layer.
US08188598B2	Bump-on-lead flip chip interconnection A semiconductor device has a semiconductor die with a plurality of bumps formed over the die. A substrate has a plurality of conductive traces formed on the substrate. Each trace has an interconnect site for mating to the bumps. The interconnect sites have parallel edges along a length of the conductive traces under the bumps from a plan view for increasing escape routing density. The bumps have a noncollapsible portion for attaching to a contact pad on the die and fusible portion for attaching to the interconnect site. The fusible portion melts at a temperature which avoids damage to the substrate during reflow. The noncollapsible portion includes lead solder, and fusible portion includes eutectic solder. The interconnect sites have a width which is less than 1.2 times a width of the conductive trace. Alternatively, the interconnect sites have a width which is less than one-half a diameter of the bump.
US08188592B2	Apparatus and method configured to lower thermal stresses An apparatus and a method configured to lower thermal stress is disclosed. One embodiment provides a semiconductor chip, a heat sink plate and a layer structure. The layer structure includes at least a diffusion solder layer and a buffer layer. The layer structure is arranged between the semiconductor chip and the heat sink plate. The buffer layer includes a material, which is soft in comparison to a material of the diffusion solder layer, and includes a layer thickness such that thermal stresses in the semiconductor chip remain below a predetermined value during temperature fluctuations within a temperature range.
US08188590B2	Integrated circuit package system with post-passivation interconnection and integration An integrated circuit package system including: providing an integrated circuit die, forming a first layer over the integrated circuit die, forming a bridge on and in the first layer, forming a second layer on the first layer, and forming bump pads on and in the second layer, the bump pads connected to ends of the bridge.
US08188587B2	Semiconductor die package including lead with end portion A semiconductor die package, and methods of making the same. The package includes a leadframe and a clip structure. The clip structure is formed, such that a portion of the clip structure points towards the semiconductor die and is coplanar with the leadframe. The semiconductor die package further includes a housing material covering at least a portion of the leadframe, the semiconductor die, and the clip structure. The housing material has an external recess that holds a portion of the clip structure.
US08188585B2	Electronic device and method for producing a device An electronic device or devices and method for producing a device is disclosed. One embodiment provides an integrated component, a first package body and a contact device. The contact device penetrates the package body.
US08188584B1	Direct-write wafer level chip scale package A method and structure provides a Direct Write Wafer Level Chip Scale Package (DWWLCSP) that utilizes permanent layers/coatings and direct write techniques to pattern these layers/coatings, thereby avoiding the use of photoimagable materials and photo-etching processes.
US08188581B2	Mechanical coupling in a multi-chip module using magnetic components A multi-chip module (MCM) is described. This MCM includes at least two substrates that are remateably mechanically coupled by positive and negative features on facing surfaces of the substrates. These positive and negative features mate with each other. In particular, a positive feature may mate with a given pair of negative features, which includes negative features on each of the substrates. Furthermore, at least one of the negative features in the given pair may include a hard magnetic material, and the positive feature and the other negative feature in the given pair may include a soft magnetic material that provide a flux-return path to the hard magnetic material. In this way, the hard magnetic material may facilitate the remateable mechanical coupling of the substrates.
US08188579B1	Semiconductor device including leadframe having power bars and increased I/O In accordance with the present invention, there is provided a semiconductor package (e.g., a QFP package) including a uniquely configured leadframe sized and configured to maximize the available number of exposed leads in the semiconductor package. More particularly, the semiconductor package includes a generally planar die pad or die paddle defining multiple peripheral edge segments. In addition, the semiconductor package includes a plurality of leads. Some of these leads include bottom surface portions which, in the completed semiconductor package, are exposed and at least partially circumvent the die pad, with other leads including portions which protrude from respective side surfaces of a package body in the completed semiconductor package. The semiconductor package also includes one or more power bars and/or one or more ground rings which are integral portions of the original leadframe used to fabricate the same.
US08188577B2	Production method of semiconductor device, semiconductor device, and exposure apparatus The present invention provides a production method of a semiconductor device, involving formation of a flattening layer and easy process for layers formed on a semiconductor layer, and also provides a semiconductor device preferably produced by such a production method.The present invention further provides an exposure apparatus preferably used in such a production method. The present invention is a production method of a semiconductor device including a semiconductor layer and a flattening layer on a substrate, the flattening layer surrounding the semiconductor layer when the substrate is viewed in plane, the production method comprising the steps of: forming the semiconductor layer on the substrate; forming a photosensitive organic film on the semiconductor layer, the photosensitive organic film having a photosensitive wavelength range overlapping with an absorption wavelength range of the semiconductor layer, and forming a flattening layer by exposing the photosensitive organic film from a side of the substrate to light having a wavelength range corresponding to the photosensitive wavelength range of the photosensitive organic film, thereby developing the photosensitive organic film.
US08188576B2	Compound for filling small gaps in a semiconductor device, composition including the compound, and method of fabricating a semiconductor capacitor A compound for filling small gaps in a semiconductor device, a composition for filling small gaps in a semiconductor device, and a method of fabricating a semiconductor capacitor, the compound including hydrolysates prepared by hydrolysis, in the presence of an acid catalyst, of compounds represented by Formulae 1, 2, and 3: [RO]3Si—[CH2]nR′ (1) wherein, in Formula 1, n is an integer from 0 to about 10, and R and R′ are each independently a hydrogen atom, a C1-C12 alkyl group, or a C6-C20 aryl group; HOOC[CH2]nR2Si—O—SiR′2[CH2]nCOOH (2) wherein, in Formula 2, each n is independently an integer from 0 to about 10, and R and R′ are each independently a C1-C12 alkyl group or a C6-C20 aryl group; and R3Si—O—X (3) wherein, in Formula 3, X is R′ or SiR′3, and R and R′ are each independently a C1-C12 alkyl group or a C6-C20 aryl group, or a polycondensate prepared by polycondensation of the hydrolysates represented by Formulae 1, 2, and 3.
US08188575B2	Apparatus and method for uniform metal plating Apparatus and methods for uniform metal plating onto a semiconductor wafer, such as GaAs wafer, are disclosed. One such apparatus can include an anode and a showerhead body. The anode can include an anode post and a showerhead anode plate. The showerhead anode plate can include holes sized to dispense a particular plating solution, such as plating solution that includes gold, onto a wafer. The showerhead body can be coupled to the anode post and the showerhead anode plate. The showerhead body can be configured to create a seal sufficient to substantially prevent a reduction of pressure in the plating solution flowing from the anode post to holes of the showerhead anode plate.
US08188570B2	Structure and method for buried inductors for ultra-high resistivity wafers for SOI/RF SiGe applications A design structure is embodied in a machine readable medium for designing, manufacturing, or testing a design. The design structure includes a high resistivity substrate and a buried inductor formed directly in the high resistivity substrate and devoid of an insulating layer therebetween.
US08188569B2	Phase change random access memory device with transistor, and method for fabricating a memory device The invention relates to a memory device, in particular to a resistively switching memory device such as a Phase Change Random Access Memory (“PCRAM”). In one disclosed method, a nanowire of non-conducting material is formed serving as a mould for producing a nanotube of conducting material. A volume of switching active material is deposited on top of the nanotube, so that the ring-shaped front face of the nanotube couples to the switching active material and thus forms a bottom electrode contact.
US08188568B2	Semiconductor integrated circuit A semiconductor circuit includes: a first diffusion layer formed on a substrate; a second diffusion layer formed in an upper part of the first diffusion layer; a third diffusion layer formed in an upper part of the second diffusion layer; a fourth diffusion layer formed in the upper part of the first diffusion layer; and a fifth diffusion formed below the third diffusion layer. A sum of a shortest distance from the third diffusion layer to the fifth diffusion layer and a shortest distance from the fifth diffusion layer or the lower end of the first diffusion layer to the fourth diffusion layer is smaller than a shortest distance from the third diffusion layer to the fourth diffusion layer. The substrate, the second and the fifth diffusion layer are a first conductivity type and the others are a second conductivity type.
US08188567B2	Semiconductor device and method for manufacturing A semiconductor and method for manufacturing a semiconductor device. In one embodiment the method includes providing a semiconductor substrate with a first substrate surface and at least one trench having at least one trench surface. The trench extends from the first substrate surface into the semiconductor substrate. The trench has a first trench section and a second trench section. The trench surface is exposed in an upper portion of the first and second trench sections and covered with a first insulating layer in a lower portion. A second insulating layer is formed at least on the exposed trench surface in the upper portion. A conductive layer is formed on the second insulating layer at least in the upper portion, wherein the second insulating layer electrically insulates the conductive layer from the semiconductor substrate. The conductive layer is removed in the first trench section without removing the conductive layer in the second trench section.
US08188563B2	Shallow-trench-isolation (STI)-bounded single-photon CMOS photodetector Techniques and apparatus for using single photon avalanche diode (SPAD) devices in various applications.
US08188560B2	Optical color sensor system An optical color sensor system is provided including providing a substrate having an optical sensor therein and forming a passivation layer over the substrate. The passivation layer is planarized and color filters are formed over the passivation layer. A planar transparent layer is formed over the color filters and microlenses are formed on the planar transparent layer over the color filters.
US08188559B2	Light-receiving element and light-receiving element array Provided are a light-receiving element which has sensitivity in the near-infrared region and in which a good crystal quality is easily obtained, a one-dimensional or two-dimensional array of the light-receiving elements is easily formed with a high accuracy, and a dark current can be reduced; a light-receiving element array; and methods for producing the same.A light-receiving element includes a group III-V compound semiconductor stacked structure including an absorption layer 3 having a pn-junction 15 therein, wherein the absorption layer has a multiquantum well structure composed of group III-V compound semiconductors, the pn-junction 15 is formed by selectively diffusing an impurity element into the absorption layer, and the concentration of the impurity element in the absorption layer is 5×1016 cm−3 or less. A diffusion concentration distribution control layer 4 has an n-type impurity concentration of 2×1015/cm3 or less before the diffusion, the diffusion concentration distribution control layer having a portion adjacent to the absorption layer, the portion having a low impurity concentration.
US08188555B2	Capacitive sensor and manufacturing method therefor A capacitive sensor includes a semiconductor substrate, a fixed electrode serving as a first electrode formed on a surface of or in the semiconductor substrate, a structure formed on the semiconductor substrate to have a vibratable second electrode that is formed to be spaced from and opposed to the semiconductor substrate and from the fixed electrode serving as the first electrode, a sealing member serving as a first sealing member formed on the semiconductor substrate to be spaced from the structure, to cover the structure, and to have a through hole serving as a first through hole, and a movable electrode serving as a vibratable third electrode formed on the sealing member to block up the through hole, and to be spaced from and opposed to the movable electrode.
US08188553B2	Semiconductor device and method for making the same In a MOS-type semiconductor device in which, on a Si substrate (201), a SiGe layer (202) having a valence band edge energy value smaller than a valence band edge energy value of the first semiconductor layer and a mobility larger than a mobility of the first semiconductor layer, a Si cap layer (203), and an insulating layer (204) are sequentially laminated, the problem of the shift of the absolute value of the threshold voltage toward a smaller value caused by negative fixed charges formed in or near the interface between the Si cap layer (203) and the insulting film (204) by diffusion of Ge is overcome by neutralizing the negative fixed charges by positive charges induced in and near the interface between the Si cap layer and the insulating film along with addition of nitrogen atoms to the semiconductor device surface by NO gas annealing and thereby shifting the threshold voltage toward a larger value.
US08188551B2	Semiconductor devices and methods of manufacture thereof Semiconductor devices and methods of manufacture thereof are disclosed. A complimentary metal oxide semiconductor (CMOS) device includes a PMOS transistor having at least two first gate electrodes comprising a first parameter, and an NMOS transistor having at least two second gate electrodes comprising a second parameter, wherein the second parameter is different than the first parameter. The first parameter and the second parameter may comprise the thickness or the dopant profile of the gate electrode materials of the PMOS and NMOS transistors. The first and second parameter of the at least two first gate electrodes and the at least two second gate electrodes establish the work function of the PMOS and NMOS transistors, respectively.
US08188546B2	Multi-gate non-planar field effect transistor structure and method of forming the structure using a dopant implant process to tune device drive current Disclosed are embodiments of a semiconductor structure that includes one or more multi-gate field effect transistors (MUGFETs), each MUGFET having one or more semiconductor fins. In the embodiments, a dopant implant region is incorporated into the upper portion of the channel region of a semiconductor fin in order to selectively modify (i.e., decrease or increase) the threshold voltage within that upper portion relative to the threshold voltage in the lower portion and, thereby to selectively modify (i.e., decrease or increase) device drive current. In the case of a multiple semiconductor fins, the use of implant regions, the dopant conductivity type in the implant regions and/or the sizes of the implant regions can be varied from fin to fin within a multi-fin MUGFET or between different single and/or multi-fin MUGFETs so that individual device drive current can be optimized. Also disclosed herein are embodiments of a method of forming the semiconductor structure.
US08188545B2	Integrated circuit device and electronic instrument A semiconductor integrated circuit includes N pad rows in which pads are respectively arranged, and electrostatic discharge protection elements disposed in a lower layer of the N pad rows and connected with each pad in the N pad rows. The electrostatic discharge protection elements are disposed in a lower layer of regions at least partially including each of the N pads.
US08188542B2	Field effect transistors including variable width channels and methods of forming the same A field effect transistor includes a first substrate region having a channel region and a second substrate region where a heavily doped region is formed. The channel region includes a first portion having a first width and a second portion having a second width larger than the first width. Related fabrication methods are also described.
US08188541B2	Vertical MOSFET with through-body via for gate In an embodiment, set forth by way of example and not limitation, a MOSFET power chip includes a first vertical MOSFET and a second vertical MOSFET. The first vertical MOSFET includes a semiconductor body having a first surface defining a source and a second surface defining a drain and a gate structure formed in the semiconductor body near the second surface. A via is formed within the semiconductor body and is substantially perpendicular to the first surface and the second surface. The via has a first end electrically coupled to the first surface and a second end electrically coupled to the gate structure. The second vertical MOSFET includes a semiconductor body having a first surface defining a source, a second surface defining a drain and a gate structure formed in the semiconductor body near the first surface. The first surface of the first vertical MOSFET and the second surface of the second vertical MOSFET are substantially co-planar and an electrically conductive can substantially surrounds the MOSFETS and shorts the first surface of the first vertical MOSFET to the second surface of the second vertical MOSFET.
US08188540B2	High breakdown voltage double-gate semiconductor device A double-gate semiconductor device includes a MOS gate and a junction gate, in which the bias of the junction gate is a function of the gate voltage of the MOS gate. The breakdown voltage of the double-gate semiconductor device is the sum of the breakdown voltages of the MOS gate and the junction gate. The double-gate semiconductor device provides improved RF capability in addition to operability at higher power levels as compared to conventional transistor devices. The double-gate semiconductor device may also be fabricated in a higher spatial density configuration such that a common implantation between the MOS gate and the junction gate is eliminated.
US08188539B2	Field-effect semiconductor device and method of forming the same A semiconductor device comprises a semiconductor layer, a body region of a first conductivity type formed in the semiconductor layer and extending from a first surface of the semiconductor layer, a first region of a second conductivity type formed in the body region, and a second region of the first conductivity type formed in the body region. The first region extends from the first surface of the semiconductor layer and provides a current electrode region of the semiconductor device. The second region surrounds the first region. The doping concentration of the first conductivity type in the second region is greater than a doping concentration of the first conductivity type in the body region.
US08188538B2	Semiconductor device and method of manufacturing semiconductor device The semiconductor device according to the present invention includes: a semiconductor layer of a first conductivity type made of SiC having an Si surface; a gate trench dug down from the surface of the semiconductor layer; a gate insulating film formed on a bottom surface and a side surface of the gate trench so that the ratio of the thickness of a portion located on the bottom surface to the thickness of a portion located on the side surface is 0.3 to 1.0; and a gate electrode embedded in the gate trench through the gate insulating film.
US08188533B2	Write once read only memory employing charge trapping in insulators Structures and methods for write once read only memory employing charge trapping in insulators are provided. The write once read only memory cell includes a metal oxide semiconductor field effect transistor having a first source/drain region, a second source/drain region, a channel region between the first and the second source/drain regions, and a gate separated from the channel region by a gate insulator. A plug couples the first source/drain region to an array plate. A bitline is coupled to the second source/drain region. The MOSFET can be programmed by operation in a reverse direction trapping charge in the gate insulator adjacent to the first source/drain region such that the programmed MOSFET operates at reduced drain source current when read in a forward direction.
US08188530B2	Nonvolatile semiconductor memory device and method for manufacturing same A semiconductor memory device provided with a cell array section and a peripheral circuit section, the device includes: a back gate electrode; a stacked body provided on the back gate electrode; a plurality of semiconductor pillars extending in a stacking direction; connection members, each of the connection members connecting one of the semiconductor pillars to another one of the semiconductor pillars; a back-gate electrode contact applying a potential to the back gate electrode; a gate electrode provided in the peripheral circuit section; and a gate electrode contact applying a potential to the gate electrode, the back gate electrode and the gate electrode respectively including: a lower semiconductor layer; a conductive layer provided on the lower semiconductor layer; and an upper semiconductor layer provided on the conductive layer, the connection members being provided in or on the upper semiconductor layer, the back-gate electrode contact and the gate electrode contact being in contact with the conductive layer.
US08188528B2	Structure and method to form EDRAM on SOI substrate A memory device is provided that in one embodiment includes a trench capacitor located in a semiconductor substrate including an outer electrode provided by the semiconductor substrate, an inner electrode provided by a conductive fill material, and a node dielectric layer located between the outer electrode and the inner electrode; and a semiconductor device positioned centrally over the trench capacitor. The semiconductor device includes a source region, a drain region, and a gate structure, in which the semiconductor device is formed on a semiconductor layer that is separated from the semiconductor substrate by a dielectric layer. A first contact is present extending from an upper surface of the semiconductor layer into electrical contact with the semiconductor substrate, and a second contact from the drain region of the semiconductor device in electrical contact to the conductive material within the at least one trench.
US08188526B2	Semiconductor device It is an object of the present invention to surely protect a predetermined semiconductor element or a predetermined semiconductor element group in an analog block from a noise generated from a digital block. A semiconductor device according to the present invention includes a semiconductor substrate, a digital block to be a region in which a digital circuit is formed and an analog block to be a region in which an analog circuit is formed, arranged by separating an upper surface of the semiconductor substrate and a substrate potential fixing region provided on the semiconductor substrate so as to surround in a planar view the predetermined semiconductor element group in the analog block, and a pad connected to the substrate potential fixing region and receiving a predetermined potential from an external part.
US08188521B2	Power semiconductor device A power semiconductor device has semiconductor layers, including: first layer of first type; second and third layers respectively of first and second types alternately on the first layer; fourth layers of second type on the third layers; fifth layers of first type on the fourth layer; sixth and seventh layers respectively of second and first types alternately on the second and third layers; a first electrode connected to the first layer; an insulation film on fourth, sixth, and seventh layers; a second electrode on fourth, sixth, and seventh layers via the insulation film; and a third electrode joined to fourth and fifth layers, wherein the sixth layers are connected to the fourth layers and one of the third layers between two fourth layers, and an impurity concentration of the third layers below the sixth layers is higher than that of the third layers under the fourth layers.
US08188517B2	Three-dimensional nonvolatile memory device and method for fabricating the same A three-dimensional nonvolatile memory device includes: a plurality of channel structures extending in parallel in a first direction and comprising a plurality of channel layers that are alternatively stacked with a plurality of interlayer insulating layers over a substrate; a plurality of memory cells stacked along sidewalls of the channel structures and arranged in the first direction and a second direction crossing the first direction; and a plurality of word lines extending in parallel in the second direction and connected to the memory cells arranged in the second direction.
US08188509B2	Organic light emitting display device An organic light emitting display device which prevents deterioration of an organic light emitting diode (OLED), the organic light emitting display device includes a first substrate including a display unit that includes at least one organic light emitting diode (OLED), a second substrate facing the first substrate and bonded to the first substrate, a sealant arranged surrounding the display unit and bonding the first substrate to the second substrate, a dam portion arranged between the display unit and the sealant and surrounding a periphery of the display unit and including a plurality of magnetic particles and a filling material arranged within an inner space of the dam portion and between the first and second substrates and including a plurality of magnetic particles.
US08188507B2	Light emitting device package and method for fabricating the same Provided are a light emitting device package and a method for fabricating the same. The light emitting device package comprises a substrate; a light emitting device on the substrate; a zener diode comprising a first conductive type impurity region and two second conductive type impurity regions, the first conductive type impurity region being disposed in the substrate, the two second conductive type impurity regions being separately disposed in two areas of the first conductive type impurity region; and a first electrode layer and a second electrode layer, each of them being electrically connected to the second conductive type impurity regions and the light emitting device.
US08188500B2	Organic light-emitting element and light-emitting device using the same An organic light-emitting element includes a first electrode, a second electrode, and at least one organic compound layer disposed between the first electrode and the second electrode. The organic compound layer includes a light-emitting layer containing a light-emitting material and being configured to emit light toward the first electrode and the second electrode. The light emitted toward the first electrode is reflected from a reflection plane located at the first electrode to cause interference with the light emitted toward the second electrode. The interference provides an interference intensity distribution having a maximum peak at a wavelength λ1. The light-emitting material of the light-emitting layer exhibits a photoluminescence spectrum having a maximum peak at a wavelength λ2. The organic light-emitting element produces an electroluminescence spectrum having a maximum peak at a wavelength λ3. These wavelengths satisfy the relationships: λ2≠λ3 and \|λ2−λ3\|<\|λ2−λ1\|.
US08188499B2	Polarized light emitting diode device and method for manufacturing the same The present invention relates to a polarized light emitting diode (LED) device and the method for manufacturing the same, in which the LED device comprises: a base, a light emitting diode (LED) chip, a polarizing waveguide and a packaging material. In an exemplary embodiment, the LED chip is disposed on the base and is configured with a first light-emitting surface for outputting light therefrom; and the waveguide, being comprised of a polarization layer, a reflection layer, a conversion layer and a light transmitting layer, is disposed at the optical path of the light emitted from the LED chip; and the packaging material is used for packaging the waveguide, the LED chip and the base into a package.
US08188497B2	Semiconductor device and method of manufacturing the same The invention is directed to providing a smaller semiconductor device with a lower manufacturing cost and higher reliability and a method of manufacturing the same. A light emitting element (a LED die 8) is formed on a first substrate 1. A cathode electrode 10 connected to an N type region of the LED die 8 is formed between the first substrate 1 and the LED die 8. The side surface of the LED die 8 is covered by an insulation layer 11. An anode electrode 12 is formed extending from on the front surface of the first substrate 1 onto a P type region of the LED die 8 along the circumference of the insulation layer 11. Wiring layers 18 electrically connected to the cathode electrode 10 and the anode electrode 12 are formed on the side surface of the first substrate 1 therealong. The wiring layers 18 extend onto the back surface of the first substrate 1. Conductive terminals 22 electrically connected to the wiring layers 18 through electrode connection layers 20 are formed on the back surface of the first substrate 1.
US08188494B2	Utilizing nanowire for generating white light One embodiment in accordance with the invention is an apparatus that can include a light emitting diode that is for of outputting light in the blue wavelength. Furthermore, the apparatus can also include a nanowire or nanoparticle coupled to a surface of the light emitting diode. Additionally, the apparatus can include an electrode coupled to the light emitting diode, wherein the nanowire or nanoparticle is for receiving and converting the light into red and green light that is output from the nanowire or nanoparticle.
US08188493B2	Light emitting diode with independent electrode patterns Abstract of DisclosureA light emitting diode includes a substrate, an N-doped layer disposed on the substrate, a plurality of cathodes disposed between the N-doped layer and the substrate, an active layer disposed on the N-doped layer, a P-doped layer disposed on the active layer, and a plurality of anodes disposed on the P-doped layer. The cathodes are electrically connected to the N-doped layer, and the patterns of the cathodes are disconnected from each other. The anodes are electrically connected to the P-doped layer, and the patterns of the anodes are disconnected from each other. Each cathode and a corresponding anode form a loop, and each loop is an independent loop.
US08188492B2	Light emitting device having plural light emitting diodes and at least one phosphor for emitting different wavelengths of light The present invention provides a light emitting device, comprising a first light emitting diode for emitting light in an ultraviolet wavelength region; at least one phosphor arranged around the first light emitting diode and excited by the light emitted from the first light emitting diode to emit light having a peak wavelength longer than the wavelength of the light emitted from the first light emitting diode; and at least one second light emitting diode for emitting light having a wavelength different from the peak wavelength of the light emitted from the phosphor. According to the present invention, there is provided a white light emitting device, wherein using a light emitting diode for emitting light different in wavelength from light that is ex-cititively emitted from the phosphor, an excitation light source, i.e., light in the ultraviolet region for exciting the phosphor is effectively used, thereby improving energy conversion efficiency and improving reliability.
US08188487B2	Surface emitting laser with trenches to define conductive regions A surface emitting laser includes a lower multilayer mirror, an active layer, and an upper multilayer mirror stacked onto a substrate. A first current confinement layer having a first electrically conductive region and a first insulating region is formed above or below the active layer using a first trench structure. A second current confinement layer having a second electrically conductive region and a second insulating region is formed above or below the first current confinement layer using a second trench structure. The first and second trench structures extend from a top surface of the upper multilayer mirror towards the substrate such that the second trench structure surrounds the first trench structure. When the surface emitting laser is viewed in an in-plane direction of the substrate, a boundary between the first electrically conductive region and the first insulating region is disposed inside the second electrically conductive region.
US08188482B2	SiC semiconductor device with self-aligned contacts, integrated circuit and manufacturing method One aspect includes a semiconductor device with self-aligned contacts, integrated circuit and manufacturing method. One embodiment provides gate control structures. Each of the gate control structures is configured to control the conductivity of a channel region within a silicon carbide substrate by field effect. A contact hole is self-aligned to opposing sidewalls of adjacent gate control structures by intermediate spacers.
US08188481B2	Display panel A display panel includes a plurality of pads, a plurality of first contacts connected to the pads, a plurality of second contacts provided so as to be opposed to the plurality of first contacts, a polysilicon layer configured to form a plurality of polysilicon films to connect the plurality of first contacts and second contacts, and a gate metal layer. The gate metal layer forms at least one gate metal. The gate metal layer traverses the plurality of polysilicon films so as to form a plurality of transistors. The plurality of transistors are arranged in a zigzag pattern for each transistor set. A width of a portion of each of the polysilicon films, the portion forming a corresponding one of the transistors, is larger than a width of another portion of the polysilicon films. The other portion is connected to a corresponding one of the first contacts and second contacts.
US08188480B2	Thin film field effect transistor and display A TFT is provided which includes, on a substrate, at least a gate electrode, a gate insulating layer, an active layer containing an amorphous oxide semiconductor, a source electrode and a drain electrode, wherein a resistance layer containing an amorphous oxide and having a thickness of more than 3 nm is disposed between the active layer and at least one of the source electrode or the drain electrode, and a band gap of the active layer is smaller than a band gap of the resistance layer. Also, a display using the TFT is provided.
US08188479B2	Pixel electrode structure having via holes disposed on common line with high display quality A pixel electrode structure includes a transparent substrate, a data line, a common line, a first array pixel, and a second array pixel disposed on the transparent substrate. The first/second array pixels respectively include a thin film transistor, a pixel electrode, and a gate line, and the common line is disposed at a lateral side of the gate line. A first via hole and a second via hole are respectively disposed on common line and in contact with an extending portion of the first thin film transistor and an extending portion of the second thin film transistor. A dummy line is disposed at a side of the data line, and a third via hole is disposed both on the dummy line and on the common line. The present invention can not only increase the aperture ratio of the pixel, but have a better stability of the common voltage signal.
US08188477B2	Semiconductor device and manufacturing method thereof As a display device has higher definition, the number of pixels is increased and thus, the number of gate lines and signal lines is increased. When the number of gate lines and signal lines is increased, it is difficult to mount IC chips including driver circuits for driving the gate lines and the signal lines by bonding or the like, whereby manufacturing cost is increased. A pixel portion and a driver circuit for driving the pixel portion are provided on the same substrate, and at least part of the driver circuit comprises a thin film transistor including an oxide semiconductor sandwiched between gate electrodes. A channel protective layer is provided between the oxide semiconductor and a gate electrode provided over the oxide semiconductor. The pixel portion and the driver circuit are provided on the same substrate, which leads to reduction of manufacturing cost.
US08188470B2	Semiconductor stacking layer and fabricating method thereof A fabricating method of a semiconductor stacking layer includes following steps. First, an amorphous silicon (a-Si) layer is formed on a substrate. Surface treatment is then performed on a surface of the a-Si layer. After that, a doped microcrystalline silicon (μc-Si) layer is formed on the treated surface of the a-Si layer, wherein interface defects existing between the a-Si layer and the doped μc-Si layer occupy an area in a cross-sectional region having a width of 1.5 micrometers and a thickness of 40 nanometers, and a ratio of the occupied area in the cross-sectional region is equal to or less than 10%. The method of fabricating the semiconductor stacking layer can be applied to a fabrication process of a semiconductor device to effectively reduce the interface defects of the semiconductor stacking layer.
US08188468B2	Compound-type thin film, method of forming the same, and electronic device using the same An organometal material gas is supplied into a low electron temperature and high density plasma excited by microwaves to form a thin film of a compound on a substrate as a film forming object. In this case, the temperature of a supply system for the organometal material gas is controlled by taking advantage of the relationship between the vapor pressure and temperature of the organometal material gas.
US08188466B2	Resistance variable element A resistance variable element is provided, which is capable of performing bipolar operation by a specified mechanism and usable as a memory. The resistance variable element has a laminated structure including an electrode, another electrode, an oxide layer between the electrodes, and an oxide layer in contact with the oxide layer between the oxide layer and the electrode. The oxide layer is switchable from the low-resistance state to the high-resistance state by donating oxygen ions to the oxide layer, and from the high-resistance state to the low-resistance state by accepting oxygen ions from the oxide layer. The oxide layer is switchable from the low-resistance state to the high-resistance state by accepting oxygen ions from the oxide layer, and from the high-resistance state to the low-resistance state by donating oxygen ions to the oxide layer.
US08188465B2	Method of manufacturing semiconductor device, semiconductor device, display device, and electronic instrument A method of manufacturing a semiconductor device includes: forming a plurality of regions extending in a predetermined direction on a substrate; and ejecting a liquid material on the plurality of regions to form an electrically conductive film, wherein the electrically conductive film extends in the same direction as the plurality of regions so as to overlap the plurality of regions.
US08188464B2	Atomic layer deposition systems and methods including metal beta-diketiminate compounds The present invention provides atomic layer deposition systems and methods that include metal compounds with at least one β-diketiminate ligand. Such systems and methods can be useful for depositing metal-containing layers on substrates.
US08188463B2	Organic light emitting diode with magnetic structure for improved current adaptability An organic light emitting device includes a cathode and an optional substrate external to the device. The device further includes at least one film layer disposed on at least one of the cathode or the substrate. The at least one film layer includes at least one of a magnetic, a mixed magnetic material, and combinations thereof. The device further includes an anode and at least one organic layer intermediate the cathode and anode.
US08188459B2	Devices based on SI/nitride structures A nitride-based semiconductor device is provided. The nitride-base semiconductor device includes a substrate comprising one or more locally etched regions and a buffer layer comprising one or multiple InAlGaN layers on the substrate. A channel layer includes GaN on the buffer layer. A barrier layer includes one or multiple AlGaN layers on the channel layer.
US08188458B2	Non-polar (Al,B,In,Ga)N quantum well and heterostructure materials and devices A method for forming non-polar (Al,B,In,Ga)N quantum well and heterostructure materials and devices. Non-polar (11 20) a-plane GaN layers are grown on an r-plane (1 102) sapphire substrate using MOCVD. These non-polar (11 20) a-plane GaN layers comprise templates for producing non-polar (Al,B,In,Ga)N quantum well and heterostructure materials and devices.
US08188456B2	Thermionic electron emitters/collectors have a doped diamond layer with variable doping concentrations A thermionic electron emitter/collector includes a substrate and a doped diamond electron emitter/collector layer on the substrate. The doped diamond electron emitter/collector layer has at least a first and a second doping concentration as a function of depth such that the first doping concentration is different from the second doping concentration.
US08188455B2	Information recording/reproducing device An information recording/reproducing device includes a recording layer, and a recording circuit which records data to the recording layer by generating a phase change in the recording layer. The recording layer includes a first chemical compound having a spinel structure. The recording layer is AxMyX4 (0.1≦x≦2.2, 1.0≦y≦2.0), where A includes one selected from a group of Zn, Cd and Hg, M includes one selected from a group of Ti, Zr, Hf, V, Nb and Ta, and X includes O.
US08188453B2	Short use system and method for adaptive radiation protection A short use or disposable system and method for adaptive window-capable radiation protection provides a disposable outer covering for securing one or more flexible and overlappable radiation shield members relative to a user using a variety of features including pockets, pocket defining members, fitting aid members, and fixing and releasing points. Features allow conveniently securing multiple layers of reusable shields in disposable coverings and providing pre-selected and assembled shielding kits for specific uses. Variants provide adaptive shielding sheets that may be customized to a particular patient need or injury profile.
US08188451B1	Electron generation and delivery system for contamination sensitive emitters Contamination may be removed from an emitter tip of a field emitter during operation of the emitter tip in a system having an electron beam column having an electrode with a beam defining aperture, an electron collector located proximate to the beam defining aperture between the electrode and the field emitter, and an electron deflector located between the emitter tip and the electron collector. At regular predetermined intervals an electron beam from the emitter tip may be deflected away from a path through the beam defining aperture and onto the electron collector. An electron beam current to the electron collector may be determined and the emitter tip may be flash heated if the current to the electron collector is below a threshold.
US08188448B2	Temperature controlled ion source An ion source is provided that utilizes the same dopant gas supplied to the chamber to generate the desired process plasma to also provide temperature control of the chamber walls during high throughput operations. The ion source includes a chamber having a wall that defines an interior surface. A liner is disposed within the chamber and has at least one orifice to supply the dopant gas to an inside of the chamber. A gap is defined between at least a portion of the interior surface of the chamber wall and the liner. A first conduit is configured to supply dopant gas to the gap where the dopant gas has a flow rate within the gap. A second conduit is configured to remove the dopant gas from the gap, wherein the flow rate of the dopant gas within the gap acts as a heat transfer media to regulate the temperature of the interior of the chamber.
US08188446B2	Fluorescence imaging apparatus The distribution of abnormal tissue, such as lesions, in an observed object is precisely detected regardless of the distribution of absorbing material present in a living organism. Provided is a fluorescence imaging apparatus (1) including an excitation-light radiating unit (2) that irradiates an observed object with excitation light of a plurality of wavelengths; a filter (14) that transmits fluorescence in a specific wavelength band from among fluorescence produced by the observed object in response to the excitation light radiated from the excitation-light radiating unit (2); a light detector (15) that detects the fluorescence transmitted through the filter (14); and a computing unit (18) that calculates a fluorescence intensity ratio in the same wavelength band in response to the excitation light of the plurality of wavelengths, which is detected by the light detector (15).
US08188445B2	Ion source An ion source includes an arc chamber having an extraction aperture, and a plasma sheath modulator positioned in the arc chamber. The plasma sheath modulator is configured to control a shape of a boundary between a plasma and a plasma sheath proximate the extraction aperture, wherein the plasma sheath modulator includes a semiconductor. A well focused ion beam having a high current density can be generated by the ion source. A high current density ion beam can improve the throughput of an associated process. The emittance of the ion beam can also be controlled.
US08188438B2	Electrokinetic microfluidic flow cytometer apparatuses with differential resistive particle counting and optical sorting An electrokinetic microfluidic flow cytometer apparatus can include a substrate, a pair of signal and noise detection channels, and a particle detection circuit. The substrate includes an input port, an output port, and a microchannel that fluidly connects the input port and the output port to allow fluid to flow therebetween. The signal and noise detection channels are defined in the substrate and are fluidly connected to the microchannel from locations that are adjacent to each other. The signal and noise detection channels extend in opposite directions away from the microchannel to receive ambient electrical noise. The particle detection circuit generates a particle detection signal in response to a differential voltage across the signal and noise detection channels, which tracks changes in resistivity across an adjacent portion of the microchannel while at least substantially canceling a common component of the ambient electrical noise.
US08188431B2	Integration of vacuum microelectronic device with integrated circuit A device includes an integrated circuit (IC) and at least one ultra-small resonant structure formed on said IC. At least the ultra-small resonant structure portion of the device is vacuum packaged. The ultra-small resonant structure portion of the device may be grounded or connected to a known electrical potential. The ultra-small resonant structure may be electrically connected to the underlying IC, or not.
US08188430B2	Omnidirectional monitoring using near-infrared electromagnetic radiation A monitoring device includes an imaging device sensitive to visible and near-infrared electromagnetic radiation. The monitoring device is configured to concurrently direct omnidirectional visible and near-infrared electromagnetic radiation onto the imaging device without using any moving parts. The monitoring device also can include multiple sources of near-infrared electromagnetic radiation, which can be sequentially operated to illuminate regions of a monitored area to improve the imaged data. The monitoring device can acquire additional data, such as acoustic data or identification data of a target, and can process the acquired data to detect any targets that may be present and evaluate an alarm condition.
US08188426B2	Quadropole mass spectrometer If a scanning rate of a mass scanning is set to be high, the amount of change in an applied voltage between a time of an incidence of a certain ion into a quadrupole mass filter and a time of an emission of the ion therefrom increases. This leads to a change in the condition of a passage of ions, causing the amount of ions to decrease and thereby deteriorating detection sensitivity. In order to avoid this problem, according to the present invention, the values of direct current voltage U and an amplitude V of radio-frequency voltage, both voltages being applied to rod electrodes during a mass scanning, are respectively determined so that a voltage ratio U/V of the voltage U to the amplitude V becomes smaller as the scanning rate becomes higher. Accordingly, in a stability diagram based on the Mathieu equation, the inclination of line L indicating the change in the applied voltage during the mass scanning becomes gradual and the amount of ions passing through the quadrupole mass filter increases particularly when the mass is high.
US08188423B2	Method and apparatus for ion fragmentation in mass spectrometry A method for fragmentation of analyte ions for mass spectroscopy and a system for mass spectroscopy. The method produces gas-phase analyte ions, produces gas-phase odd-electron containing species separately from the analyte ions, and mixes the gas-phase analyte ions and the odd-electron containing species at substantially atmospheric pressure conditions to produce fragment ions prior to introduction into a mass spectrometer. The system includes a gas-phase analyte ion source, a gas-phase odd-electron containing species source separate from the gas-phase analyte ion source, a mixing region where the gas-phase analyte ions and the odd-electron containing species are mixed at substantially atmospheric pressure to produce fragment ions of the analyte ions, a mass spectrometer having an entrance where at least a portion of the fragment ions are introduced into a vacuum of the mass spectrometer, and a detector in the mass spectrometer which determines a mass to charge ratio analysis of the fragment ions.
US08188421B2	Optical encoder for detecting the relative displacement between an encoder scale and an encoder head An optical encoder comprises an encoder head and a scale having a second grating that has an optical pattern. The encoder head has a light emission unit to emit specific light to the scale, a light transmission member to transmit the light emitted from the light emission unit and a light detection unit having light detection elements arranged at a predetermined pitch. The light transmission member has a first grating having an optical pattern of a predetermined pitch and an aperture to narrow the light emitted from the light emission unit and impinging on the second grating of the scale. A motion of an image on the light detection elements of the light detection unit is detected. The image is formed by the light reflected or diffracted by the second grating of the scale after the light impinges on the scale through the light transmission member.
US08188418B1	Switchable hybrid receiver for coherent and direct optical detection Embodiments of the present invention provide a switchable dual-mode detection system that can be electronically or optically switched between direct and coherent detection. The dual-mode detection system comprises a photo detector and one or more switching elements used in conjunction with the photo detector to electronically or optically switch the detection system between direct and coherent detection. The switching elements may include a switchable detector driver that selectively biases the photo detector into a low gain mode for coherent detection and a high gain mode for direct detection, and/or a switchable optical subsystem that selectively mixes a local oscillator beam with the input signal beam for coherent detection and not for direct detection, and/or an amplifier switch that selectively directs the output photo current of the photo detector to one of two amplifiers, where one of the amplifiers is optimized for direct detection and the other for coherent detection.
US08188417B2	Light detecting device In a photodetecting device 3, a wiring board 12 is provided at the front surface side of a photodetecting element 11 so that a first bonding pad region 15 formed on the front surface of the photodetecting element 11 is exposed, and second bonding pads 17B are formed, of the wiring board 12, in the region on a further inner side than first bonding pads 17A. Thereby, in the photodetecting device 3, a forming space for wire bonding can be located at the inside of the photodetecting element 11, so that the wiring board 12 and the photodetecting element 11 can be made almost equal in size. As a result, in the photodetecting device 3, the area that the photodetecting element 11 occupies relative to the photodetecting device 3 can be sufficiently secured, and minimization of the non-sensitive region in the case of a buttable arrangement of the photodetecting devices 3 on a cold plate 2 can be realized.
US08188416B2	Engineered phantoms for perfusion imaging applications In various embodiments, microengineered phantoms with microvascular networks serve as calibration standards for perfusion imaging systems.
US08188414B2	Grid support system for a tracker-mounted solar panel array for rooftop applications A grid support system for tracker-mounted solar panel array for rooftop applications includes a base frame having a plurality of interconnected lateral members which define a generally planar area substantially parallel with the rooftop. The system also includes a set of support legs corresponding to each one of the tracker devices. The set of support legs are secured to the lateral members and extend upward and inward toward one another to a respective tracker mounting plate. The tracker mounting plate supports a tracker device and associated solar panel(s). A plurality of ballast trays are secured to the base frame and are adapted to hold a plurality of ballast weights for applying a downward force on the base frame to stabilize and resist movement of the base frame.
US08188412B2	Confocal microscope which weights and combines signals output from a plurality of photodetectors and calculates omnifocal brightness information for the plurality of signals A confocal microscope includes an objective lens for converging light which is emitted from a light source to a sample, a scanning mechanism for relatively scanning the sample with the light converged to the sample, and a plurality of confocal diaphragm apertures that are arranged at positions optically conjugate to the light-gathering position of the objective lens and have different diaphragm diameters. The confocal microscope further includes a plurality of photodetectors for detecting the intensities of lights respectively transmitting through the confocal diaphragm apertures, and a weighting/combining arithmetic processing unit for combining signals output from the photodetectors after weighting the signals.
US08188409B2	Temperature probe for an oven, oven and method for operating an oven The invention relates to a temperature probe for an oven, comprising in one embodiment a longitudinal housing in the form of a spit. A temperature sensor and an electronic unit are arranged in a tip and are connected at the other end to emitting means. The temperature probe comprises a thermogenerator for producing energy. The thermogenerator uses a temperature difference between a higher temperature inside the oven and a lower core temperature in a food product, such as roast, in which the temperature probe is inserted, for producing energy for operating the emitting means.
US08188405B2	Electric arc welding machine and operating method with modular unit enclosing cooling unit A welding machine has a welding unit for generating a welding voltage/current, and at least one welding tool connectable to the welding unit by a cable. The welding unit has a closed protective casing, and a cooling unit for cooling the welding tool and/or cable on command. A modular unit containing the cooling unit is insertable and easily removable from inside the casing and is closed for protection of the welding unit.
US08188404B2	Laser processing method and laser processing apparatus In six rows of molten processed regions 131, 132, the molten processed region 131 closest to a front face 17a of a metal film 17 opposing a front face 3 of an object to be processed 1 acting as a laser light entrance surface is formed by irradiating a silicon wafer 11 with a reflected light component of laser light L reflected by the front face 17a of the metal film 17. This can form the molten processed region 131 very close to the front face 17a of the metal film 17.
US08188399B2	Fitting a light guide sheet to a keypad using protrusions In an embodiment, the invention provides a keypad assembly comprising a keypad, a light guide sheet, a dome sheet, and a board. The keypad comprises at least one protrusion and at least one rib. The light guide sheet has openings that are smaller than a first portion of the at least one protrusion. The dome sheet and the board have openings that are larger than a first portion of the at least one protrusion. The at least one protrusion is compressible such that the first portion of the at least one protrusion is extendable through the openings in the light guide sheet, the dome sheet and the board. The at least one rib physically contacts at least a portion of the light guide sheet.
US08188395B2	Electric switch The invention relates to an electrical switch for an electrical appliance, in particular for an electrical tool, such as a drill, a grinder, a saw, a plane, an angle grinder or the like, and having a housing. The switch has a contact system which is located in the housing, and electrical connections, which lead into the housing and/or are located in the housing, for electrical supply lines to the contact system. Furthermore, the switch may have an operating member for switching action on the contact system, with the contact system being operatively connected to the operating member by means of an elastic element. The electrical connections have seals.
US08188392B2	Serrated contact members A contactor has two contact elements (1, 2) each having a contact member (3, 4) adapted to bear with the contact side (5, 6) thereof against a said contact side of the other contact member for enabling an electric current to flow between said to contact elements. The contact sides of both contact members are provided with serration's (11, 12) extending so that elongated ridge-like peaks (13) of serration's of one said contact side intersect such peaks of the other said contact side while forming a plurality of spots of mutual contact of these contact sides distributed over the area of said contact sides.
US08188388B2	Operation key structure A small-sized operation key, permits various kinds of inputs by a user to be detected and imparts the user with a tactile sensation in correspondence with each input to enable him/her to recognize his/her input. An operation key has a dome-like structure, a pressure detecting portion, a sheet member placed on the dome-like structure and pressure detecting portion, having a plate-like portion, and further having at least one first pusher and at least one second pusher formed on the lower surface of the plate-like portion, and an operating portion provided on the upper surface of the sheet member. In the operation key structure, the dome-like structure and the first pusher face each other and the pressure detecting portion and the second pusher face each other, and an initial load is applied to the pressure detecting portion by the second pusher.
US08188387B2	Keyswitch and keyboard A keyswitch includes a key cap, a base, a first support member, a second support member and a link member. The base has a first restraining portion and a third restraining portion. The first support member is disposed between the key cap and the base. The first support member has a second restraining portion. The first restraining portion restrains the second restraining portion from moving in a direction perpendicular to the base. The second support member is disposed between the key cap and the base and opposite to the first support member. The second support member has a fourth restraining portion. The third restraining portion restrains the fourth restraining portion from moving in the direction perpendicular to the base. When the key cap is pressed to a bottom of the base, the second and fourth restraining portions are located under the first and third restraining portions respectively.
US08188385B2	Determination of the mass of a vehicle A method and device for provisionally determining the mass of a vehicle when it is initialized. After initialization of the vehicle, the method determines a vehicle mass value by a static mass determination method and then checks whether this value is within a predetermined tolerance band around the dynamically last-determined vehicle mass value, which has been stored for that purpose. If this is so, and there has in the meantime been no significant change of the vehicle's mass, the previously stored dynamic vehicle mass value is probably more accurate and is used in the determination. Otherwise it can be assumed that the vehicle mass value has changed substantially, and the statically determined vehicle mass value is therefore used until a device for the dynamic determination of a vehicle mass can supply a more accurate vehicle mass value after a short time.
US08188384B2	Weighing conveyor belt with flexible transition area to pre-tension the belt One problem with weighing conveyors is that the tension of the conveyor belt, needed to allow the belt to be driven, inadvertently reduces the degree of sagging of the belt caused by the mass of the product on the belt, which affects weighing accuracy, as this pre-tensioning of the belt inadvertently supports some of the weight of the product being transported, and this tension supported fraction of the weight cannot be sensed by the load cell supporting the middle section of the belt. In a preferred embodiment, a flexible transition area is formed in-between the outer edges of the belt and the middle, product transport area, wherein the transition area comprises openings that serve to weaken the belt locally, such that a pre-tensioning of the middle part of the conveyor belt is reduced; this allows the middle part of the conveyor belt to hang substantially slack even as the outer edges of the conveyor belt are driven.
US08188383B2	Combination weighing apparatus with conveyor apparatus having coaxial sprial members A combination weighing apparatus includes a distribution unit, a plurality of conveying units and a plurality of weighing hoppers. At least one of the conveying units has a trough and a plurality of spiral members. The trough has an inside edge positioned below the distribution unit and an outside edge positioned above the weighing hopper. The spiral members are placed above a bottom surface of the trough with each of the spiral members defining an external peripheral surface. The spiral members are configured and arranged to be rotatably driven to convey the product material supplied from the distribution unit in a vicinity of the inside edge, along the external peripheral surfaces toward a vicinity of the outside edge. The spiral members are configured and arranged to stop movement of the product material on the external peripheral surfaces when the spiral members are not rotatably driven.
US08188382B2	Leadthrough for passing conduits through constructional components A leadthrough for passing conduits (6) through a constructional component (5) includes a circumferentially closed housing (12), an insert (21) of intumescent material located in the housing (12), and a first and second diaphragm-shaped sealing members (31, 36) formed, respectively, of an elastic material, and a textile flat material, each having a through-opening (32, 37) and both located in the housing (12), with the second sealing member (36) having a transition temperature of at least 600° C.
US08188380B2	Printed wiring board and method for manufacturing printed wiring board A printed wiring board and a method for manufacturing the same are provided. The printed wiring board includes a resin insulation layer having a first surface and a second surface opposite the first surface, and includes an opening for a first via conductor. An electronic-component mounting pad is formed on the first surface of the resin insulation layer. The electronic-component mounting pad includes a portion embedded in the resin insulation layer and a portion protruding from the resin insulation layer. The protruding portion covers the embedded portion and a portion of the first surface of the resin insulation layer that surrounds the embedded portion. A first conductive circuit is formed on the second surface of the resin insulation layer. A first via conductor is formed in the opening of the resin insulation layer and connects the electronic-component mounting pad and the first conductive circuit.
US08188379B2	Package substrate structure A package substrate structure includes: a substrate having a first surface and an opposing second surface and characterized by a plurality of wire-bonding pads provided on the first surface of the substrate, a plurality of ball-implanting pads provided on the second surface of the substrate, and at least a cavity formed to penetrate the first and second surfaces of the substrate; a metal board mounted on the second surface of the substrate and covering the cavity, wherein the metal board has a thickness greater than that of the ball-implanting pads and has an area greater than that of the cavity; and solder masks disposed on the first and second surfaces of the substrate respectively and having at least a solder-mask cavity corresponding in position to the cavity of the substrate, the solder masks further having a plurality of openings for exposing the wire-bonding pads, the ball-implanting pads and the metal board.
US08188372B2	Flex-rigid printed wiring board and manufacturing method thereof A flex-rigid printed wiring board is provided which can retain flexibility of a flexible portion while increasing durability of the flexible portion against folding, and can ensure conduction in a rigid portion, and a method of manufacturing the printed wiring board.The flex-rigid printed wiring board includes a conductor layer provided on at least one face of a base film, one region of the wiring board containing the base film being a rigid region, an another region containing the base film being a flexible region. The average thickness “tf” of the conductor layer on the base film formed in the flexible region and the average thickness “tR” of the conductor layer on the base film formed in the rigid region satisfy the relationship of tf
US08188368B2	Protector for wire harness A protector for a wire harness has a U-shaped main body casing for receiving a wire harness and a lid for closing an opening in the main body casing. The main body casing has opposite longitudinal ends with inlet and outlet portions for passing the wire harness. The inlet and outlet portions define tape-supports to be secured to the wire harness by tape-wrapping. A tape-support also is provided on a longitudinal end of the lid at a side of at least one of the inlet and outlet portions. The tape-support of the lid is slanted to contact an outer surface of the wire harness. The wire harness is disposed between the tape-supports of the lid and the main body casing. A tape is wound around the tape-supports of the main body casing and the lid to secure these portions to the wire harness.
US08188366B2	Integrated solar energy conversion system, method, and apparatus A solar energy conversion package includes a photovoltaic (PV) cell, a thermionic or thermoelectric conversion unit and a thermal heating system. Solar radiation is concentrated by a lens or reflector and directed to the PV cell for electrical power conversion. A water circulation system maintains the PV cell at working temperatures. The thermionic or thermoelectric conversion cell is coupled between these cells in the thermal path to generate additional power. Additional efficiencies may be gained by partitioning the solar radiation with prisms or wavelength specific filters or reflective coatings into discrete spectrum segments optimized for each conversion unit for maximizing efficiency of electrical energy conversion and equipment design. Integrating all three of these conversion techniques produces a synergistic system that exceeds the performance conventional solar conversion systems.
US08188364B2	Heterojunction photovoltaic cell with dual doping and method of manufacture The invention concerns a photovoltaic cell comprising a heterojunction between a crystalline semiconductor substrate (210) of first conductivity type and a first amorphous layer (220) in the same semiconductor material and of a second conductivity type opposite the first type and having a dopant concentration of between 1.1019 and 1.1022 atoms/cm3. The photovoltaic cell further comprises a second amorphous layer (225) of same conductivity type as the first layer and having a dopant concentration of between 1.1016 and 1.1018 atoms/cm3, said second layer being deposited directly on a first face of the substrate and being coated with said first layer. Finally, on a second face of the substrate opposite the first face, the cell comprises a third amorphous layer (260), in the same material as the substrate and of same conductivity type with a dopant concentration of between 1.1019 and 1.1022 atoms/cm3.
US08188363B2	Module level solutions to solar cell polarization A solar cell module includes interconnected solar cells, a transparent cover over the front sides of the solar cells, and a backsheet on the backsides of the solar cells. The solar cell module includes an electrical insulator between the transparent cover and the front sides of the solar cells. An encapsulant protectively packages the solar cells. To prevent polarization, the insulator has resistance suitable to prevent charge from leaking from the front sides of the solar cells to other portions of the solar cell module by way of the transparent cover. The insulator may be attached (e.g., by coating) directly on an underside of the transparent cover or be a separate layer formed between layers of the encapsulant. The solar cells may be back junction solar cells.
US08188357B2	Graphical user interface and methods of use thereof in a multimedia player In a portable multimedia device, a method, apparatus, and system for providing user supplied configuration data are described. In one embodiment, a hierarchically ordered graphical user interface is provided. A first order, or home, interface provides a highest order of user selectable items each of which, when selected, results in an automatic transition to a lower order user interface associated with the selected item. In one of the described embodiments, the lower order interface includes other user selectable items associated with the previously selected item from the higher order user interface.
US08188355B2	Adjustable depth snare drum A snare drum having four cylindrical members which nest within and are permanently attached to each other from the top shell of the drum. The top ends of the four cylindrical members are located adjacent to each other and the bottom ends of the third and fourth cylindrical members are located below the bottom ends of the first and second cylindrical members. A fifth cylindrical member slides axially along the lower end of the third cylindrical member. The top ends of the four cylindrical members are covered by a first drum head and the bottom ends of the third and fourth cylindrical members are covered by a second drum head. The four cylindrical members are the top shell for the drum and the fifth cylindrical member is the bottom shell for the drum. The distance between the first and second drum heads change as the fifth cylindrical member is manually moved axially along the third cylindrical member.
US08188347B1	Maize variety inbred PH12S2 A novel maize variety designated PH12S2 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH12S2 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH12S2 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH12S2 or a locus conversion of PH12S2 with another maize variety.
US08188345B2	Cotton variety ST 5458B2RF The cotton variety ST 5458B2RF is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and cotton lint as well as to hybrid cotton plants and seeds obtained by repeatedly crossing plants of variety ST 5458B2RF with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of ST 5458B2RF and to plants of ST 5458B2RF reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from ST 5458B2RF.
US08188341B2	Soybean cultivar 82264565 A soybean cultivar designated 82264565 is disclosed. The invention relates to the seeds of soybean cultivar 82264565, to the plants of soybean 82264565, to plant parts of soybean cultivar 82264565 and to methods for producing a soybean plant produced by crossing soybean cultivar 82264565 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean variety 82264565, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 82264565 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing the cultivar 82264565 with another soybean cultivar.
US08188340B2	Lettuce cultivar Manitou A lettuce cultivar, designated Manitou, is disclosed. The invention relates to the seeds of lettuce cultivar Manitou, to the plants of lettuce cultivar Manitou and to methods for producing a lettuce plant by crossing the cultivar Manitou with itself or another lettuce cultivar. The invention further relates to methods for producing a lettuce plant containing in its genetic material one or more transgenes and to the transgenic lettuce plants and plant parts produced by those methods. This invention also relates to lettuce cultivars or breeding cultivars and plant parts derived from lettuce cultivar Manitou, to methods for producing other lettuce cultivars, lines or plant parts derived from lettuce cultivar Manitou and to the lettuce plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid lettuce seeds, plants, and plant parts produced by crossing cultivar Manitou with another lettuce cultivar.
US08188328B2	Endothermic hydrocarbon conversion process The present invention is an improved cyclic, endothermic hydrocarbon conversion process and a catalyst bed system for accomplishing the same. Specifically, the improved process comprises reacting a hydrocarbon with a multi-component catalyst bed in such a manner that the temperature within the catalyst bed remains within controlled temperature ranges throughout all stages of the process. The multi-component catalyst bed comprises a reaction-specific catalyst physically mixed with a heat-generating material.
US08188327B1	Isooctene/isooctane process This invention covers a process for dimerizing of isobutylene to Iso-octene and unique configuration is being disclosed, where the Feed is diluted to low level with recycle which has essentially no Iso-octene, dual catalyst system, new selectivator (IPA) and successive catalyst stages if needed to enhance the conversion. The process is very selective and provides higher isobutylene conversion.Additionally the invention also covers the hydrogenation of olefins to Paraffin, Iso-octene to Iso-octane product under moderate conditions and with dual or single catalyst system.
US08188324B2	Preparation of 11C methyl iodide A process for the preparation of 11C methyl iodide comprises coating the internal surface of a first reaction vessel with a solution of lithium aluminum hydride, wherein the first reaction vessel has an internal diameter not greater than about 1.5 mm; introducing 11C carbon dioxide into the first reaction vessel such that it is reduced by the lithium aluminum hydride to give a reduction product; and reacting the reduction product with hydriodic acid.
US08188320B2	Process for preparing pure cyclododecanone The present invention relates to a process for preparing at least one cyclic compound with Z cycles and 7 to 16 carbon atoms with a keto group, at least comprising the stages: (a1) oxidation of a composition (A), at least comprising one cyclic olefin with Z cycles and 7 to 16 carbon atoms and at least two C—C double bonds, by means of dinitrogen monoxide to give a composition (A1), (a2) separating off the at least one cyclic olefin with Z cycles and 7 to 16 carbon atoms with at least two C—C double bonds from the composition (A1) in order to obtain a composition (A2), and (b) distillative treatment of the composition (A2) from step (a2) in order to obtain a composition (B), comprising the at least one cyclic compound with Z cycles and 7 to 16 carbon atoms with a keto group and less than 1.0% by weight of the at least one compound with Z−1 cycles and 7 to 16 carbon atoms with at least one aldehyde group, where Z can be 1, 2, 3 or 4.
US08188316B2	Integrated process for the preparation of polybenzimidazole precursors Processes are provided for preparing complexes of 2,3,5,6-tetraaminotoluene with an aromatic diacid where the aromatic diacid is insoluble in water under ambient conditions. An integrated process design starting with nitration of 2,6-dihalotoluene eliminates costly intermediate drying and recrystallization steps. Handling of solid materials with possible skin sensitizing properties and toxicity is avoided, thereby eliminating human and environmental exposure.
US08188309B2	Process for preparing aromatic carboxylic acids The present invention relates to a process for making terephthalic acid by reacting a starting material and oxygen in the presence of a heterogeneous catalyst and p-xylene as solvent to produce a solution of terephthalic acid (TPA). The starting material is p-xylene, p-toluic acid, 4 carboxybenzaldehyde, or a mixture of any two or more thereof. No solid TPA is formed during the reaction in contrast to previous manufacturing methods that utilize acidic solvents and precipitate TPA as it forms. By avoiding the direct precipitation of TPA during formation, the present methods avoid many shortcomings of the conventional manufacturing methods used to produce TPA. In particular, the present methods do not require additional purification steps to remove reaction byproducts; film grade TPA can be obtained directly from starting material in a one-step process.
US08188305B2	Method of producing biodiesel with supercritical alcohol and apparatus for same A method is disclosed for obtaining an alkyl ester fuel, i.e., a biodiesel, and alcohol from a feedstock mixture of free fatty acids and/or glycerides mixed with a simple alcohol, such as methanol. The method uses an electrostatic probe to provide an electrical field within the reactor. This causes the glycerin molecules to precipitate out of the feedstock mixture. A drain is provided in the reactor, to drain the glycerin from the reactor. When the precipitated glycerin reaches a level to make contact with the electrostatic probe, an electrical circuit is closed, which causes the drain to open. When the level drops, the drain closes. Glycerin absorbs water and draining glycerin from the reactor naturally dehydrates the fuel.
US08188302B2	Hydroamination of alkenes A method includes reacting an amino group, a composition including rhodium and an organic ligand, and a substrate having structural formula (I) in a reaction mixture. R1 is an organic group including a sp3 carbon atom bonded to CA. R2 is selected from the group consisting of hydrogen, methyl, and an organic group including a sp3 carbon atom bonded to CA. R3 and R4 independently are selected from the group consisting of hydrogen, methyl, and an organic group including a sp3 carbon atom bonded to CB. The method further includes forming a hydroaminated product in the reaction mixture.
US08188300B2	Atorvastatin calcium propylene glycol solvates Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications.
US08188299B2	Acrylate derivatives, alcohol derivatives, and method for producing them Provided are an acrylate derivative useful as a raw material of a polymer compound for resist compositions capable of giving resist patterns which are excellent in lithographic performance and have a good shape, an intermediate thereof (alcohol derivative) and production processes for them. To be specific, it is an acrylate derivative represented by a formula shown below: (wherein R1 represents a hydrogen atom, methyl or trifluoromethyl; R2, R3, R5, R7, R8, R9 and R10 each represent independently a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; R4 and R6 each represent independently a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms, or both of R4 and R6 are combined to represent an alkylene group having 1 to 3 carbon atoms, —O— or —S—; and R11 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or a cyclic hydrocarbon group having 3 to 10 carbon atoms).
US08188298B2	Synthetic route to ABCD-porphyrins A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described.
US08188292B2	Insecticidal N-substituted (heteroaryl)alkyl sulfilimines N-Substituted (heteroaryl)alkyl sulfilimines are effective at controlling insects.
US08188290B2	Process for preparing N, N-substituted carbamoyl halides The present invention relates to a new and useful process for preparing N,N-substituted carbamoyl halides from secondary amines, carbon dioxide, trialkylsilyl chloride and a halogenating agent.
US08188287B2	Piperidyl acrylamide antagonists of CCR2 The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5 and X are as defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is uveitis, including acute, recurring or chronic uveitis. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
US08188286B2	Process for production of azabicycloalkanol derivative The object is to produce an azabicycloalkanol derivative, particularly a cis-3-substituted-3-azabicyclo[3.2.1]octan-8-ol derivative which is a useful intermediate for agricultural chemicals or pharmaceutical agents, with a good yield and at an industrially low cost. A diastereomer of an azabicyclo-C6-10-alkanol derivative having a methyne substituted a hydroxyl group as an asymmetric carbon (e.g., a trans-3-substituted-3-azabicyclo[3.2.1]-8-ol derivative) is isomerized in the presence of a transition metal complex, thereby producing an excess amount of a thermodynamically more stable one of diastereomers (e.g., a cis-3-substituted-3-azabicyclo[3.2.1]-8-ol derivative). In this manner, a thermodynamically more stable one of diastereomers of the azabicyclo-C6-10-alkanol derivatives can be produced.
US08188279B2	Therapeutically useful substituted hydropyrido [3,2,1-ij] quinoline compounds Disclosed herein are compounds represented by the structural formula: therapeutic methods, compositions, and medicaments related thereto are also disclosed.
US08188278B2	Photosensitizer dye and dye sensitized solar cell A photosensitizer dye is provided and it is a ruthenium-based complex represented by formula (1): wherein X1 is one of formulae (2) to (7) and X2 is hydrogen (H) or the same as X1.
US08188270B2	Polymorphous form of 5-chloro-N-({(5S)-2-oxo-3[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide The present invention relates to a novel polymorphic form and the amorphous form of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophene-carboxamide, processes for their preparation, medicaments comprising these forms, and their use in the control of diseases.
US08188264B2	RNAi mediated knockdown of NuMA for cancer therapy This invention relates to the use of short interfering nucleic acid molecules (siRNA) to inhibit Nuclear Mitotic Apparatus Protein (NuMA) gene expression and their use in treatment of disease, including cancer.
US08188260B2	Versatile acylation catalytic RNAs and uses thereof An object of the present invention is to provide novel ribozyme systems capable of catalyzing tRNA acetylation using various carboxylic acids as acyl donors and uses thereof. Disclosed is a ribozyme catalyzing tRNA acetylation having a structure consisting of the RNA sequence represented by: (formula 1) P1-Z1Z2Z3Z4(N1)1(N1)2 . . . (N1)p-P2-(N2)1(N2)2 . . . (N2)q Y1Y2Y3-(N3)1(N3)2-N4GGN wherein (N1)1-(N1)p each independently represent any monoribonucleotide of U, C, A, and G; p represents 3 or 4; (N2)1-(N2)q each independently represent any monoribonucleotide of U, C, A, and G; q represents 5 or 6; (N3)1-(N3)2 each independently represent any monoribonucleotide of U, C, A, and G; N4 represents any monoribonucleotide of U, C, A, and G; Z1-Z4 each independently represent C or G; Y1-Y3 each independently represent C or G; N represents a monoribonucleotide complementary to A or G; and P1 and P2 represent a domain consisting of any RNA sequence capable of having a stem-loop structure.
US08188256B2	Primer and probe for detection of Mycobacterium intracellulare The present invention discloses an oligonucleotide which comprises a part or the entire sequence of the nucleotide sequence shown in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or SEQ ID NO: 8, or a part or the entire sequence of a sequence complementary to the nucleotide sequence shown in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or SEQ ID NO: 8, wherein the oligonucleotide is capable of hybridizing with a nucleotide sequence of Mycobacterium intracellulare gene; a primer or a probe for the detection of M. intracellulare, which comprises the aforementioned oligonucleotide; and a method for detection of M. intracellulare using the aforementioned primer and/or the probe.According to the detection method of the present invention, any false-positive result in diagnosis can be eliminated and detection or diagnosis of M. intracellulare can be carried out with higher accuracy, more preciseness, and more specifically compared to a conventional diagnostic method employing a cell culture assay or a PCR assay. The method also enables to quantify a microbial cell.
US08188254B2	C-class oligonucleotide analogs with enhanced immunostimulatory potency The invention relates to a class of CpG immunostimulatory oligonucleotides containing a CpG immunostimulatory motif and a second motif which is capable of forming secondary structure, including duplex and higher order structures, in vitro and in vivo. The oligonucleotides of the invention are useful as adjuvants in vaccination. The oligonucleotides are also useful for inducing an immune response, inducing expression of a type I interferon (IFN), inducing expression of gamma interferon (IFN-γ), and for treating a variety of conditions, including allergy, asthma, infection, and cancer.
US08188249B2	Nucleic acid molecules encoding antibodies to M-CSF The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to a M-CSF, preferably human M-CSF, and that function to inhibit a M-CSF. The invention also relates to human anti-M-CSF antibodies and antigen-binding portions thereof. The invention also relates to antibodies that are chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulins derived from human anti-M-CSF antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-M-CSF antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-M-CSF antibodies. The invention also relates to transgenic animals and transgenic plants comprising nucleic acid molecules of the present invention.
US08188247B2	Conjugates and compositions for cellular delivery This invention features conjugates, compositions, methods of synthesis, and applications thereof, including folate derived conjugates of nucleosides, nucleotides, non-nucleosides, and nucleic acids including enzymatic nucleic acids and antisense nucleic acid molecules.
US08188245B2	Enduracidin biosynthetic gene cluster from streptomyces fungicidicus This disclosure describes the molecular cloning of an enduracidin biosynthetic gene cluster from Streptomyces fungicidicus, and characterization of individual genes in the gene cluster and the proteins encoded thereby. An enduracidin gene cluster is located within a 116 kilobases genetic locus and includes 25 open reading frames (ORFs). An additional 23 ORFs flank the disclosed enduracidin biosynthetic gene cluster. Enduracidin analogs and a method for producing them by manipulation of the enduracidin gene cluster and specific genes therein are also disclosed.
US08188244B2	Carcinoembryonic antigen fusions and uses thereof Polynucleotides encoding carcinoembryonic antigen (CEA) fusion proteins are provided, the CEA fusion proteins comprising a CEA protein, or functional variant thereof, fused to a substantial portion of an immunoenhancing element. The polynucleotides of the present invention can elicit an immune response in a mammal, which, in preferred embodiments, is stronger than the immune response elicited by a wild-type CEA. The gene encoding CEA is commonly associated with the development of human carcinomas. The present invention provides compositions and methods to elicit or enhance immunity to the protein product expressed by the CEA tumor-associated antigen, wherein aberrant CEA expression is associated with a carcinoma or its development. This invention specifically provides adenoviral vector and plasmid constructs carrying polynucleotides encoding CEA fusion proteins and discloses their use in vaccines and pharmaceutical compositions for preventing and treating cancer.
US08188241B2	Immobilized proteins and methods and uses thereof The invention relates to the field of covalently attaching proteins to a substrate, particularly to methods of immobilizing proteins by posttranslationally modifying a cysteine residue of said protein through the addition of functional groups. The invention also relates to biological molecules used in such techniques, including proteins, and detection methods and kits that utilize such immobilized proteins, such as a microdevice or “protein chip”, a high-throughput screening device, and for the microscopy of proteins on a surface.
US08188240B2	Tab molecules The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
US08188239B2	Multivalent carriers of bi-specific antibodies Provided herein are targetable constructs that are multivalent carriers of bi-specific antibodies, i.e., each molecule of a targetable construct can serve as a carrier of two or more bi-specific antibodies. Also provided are targetable complexes formed by the association of a targetable construct with two or more bi-specific antibodies. The targetable constructs and targetable complexes of the invention are incorporated into biosensors, kits and pharmaceutical compositions, and are used in a variety of therapeutic and other methods.
US08188238B2	Recombinantly produced antibody An antibody capable of potentiating immune responses and modifying existing states of immune responsiveness is described, as is the sequence of the antibody. Also described are compositions containing the antibody, as well as methods for using the antibody and the compositions to enhance immune responses, to enhance DC function, to modify an existing state of immune responsiveness, to immunize individuals, or to treat or inhibit conditions such as allergic asthma.
US08188235B2	Antibodies to IL-6 and their uses Antibodies and antigen-binding portions thereof that bind to human IL-6 are provided. Also provided are nucleic acids encoding such antibodies and antigen binding portions, methods of making such antibodies and antigen binding portions, compositions comprising such antibodies or antigen binding portions, and uses of such antibodies or antigen binding portions.
US08188233B2	1B20 PCSK9 antagonists Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.
US08188225B2	Inorganic phosphate assays Binding of inorganic phosphate to a phosphate binding protein can result in changes to the stacking of appropriately positioned chromophores, thereby resulting in a detectable change. The invention provides a phosphate-binding protein that undergoes a conformational change from an initial conformation to a final conformation upon binding of phosphate, wherein the protein carries a first label and a second label, and wherein the first and second labels are arranged such that they exhibit molecular stacking that is perturbed on changing from one conformation to the other. Preferred labels are rhodamines.
US08188210B2	Naphthoxazine benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode A naphthoxazine benzoxazine-based monomer is represented by Formula 1 below: In Formula 1, R2 and R3 or R3 and R4 are linked to each other to form a group represented by Formula 2 below, and R5 and R6 or R6 and R7 are linked to each other to form a group represented by Formula 2 below, In Formula 2, * represents the bonding position of R2 and R3, R3 and R4, R5 and R6, or R6 and R7 of Formula 1. A polymer is formed by polymerizing the naphthoxazine benzoxazine-based monomer, an electrode for a fuel cell includes the polymer, an electrolyte membrane for a fuel cell includes the polymer, and a fuel cell uses the electrode.
US08188203B2	Copolymerizable azo compounds and articles containing them Polymerizable light absorbing azo dyes are disclosed useful as monomers in the formation of devices such as, but not limited to ocular lenses. Specifically, intraocular lenses (IOL) are disclosed wherein one or more of the light absorbing dye is covalently bonded to other structural polymers though ethylene unsaturated groups. The resulting IOLs possess light absorbing properties without significant amounts of free (un-bound) azo dye molecules present in the final structural polymer matrix.
US08188201B2	Bulk polymerization process for producing polydienes A process for preparing a polydiene, the process comprising the step of polymerizing conjugated diene monomer with a lanthanide-based catalyst system including the combination or reaction product of: (a) a lanthanide compound selected from the group consisting of lanthanide organophosphates, lanthanide organophosphonates, and lanthanide organophosphinates, (b) an alkylating agent, and (c) a chlorine-containing compound, where said step of polymerizing takes place within a polymerization mixture that includes less than 20% by weight of solvent based on the total weight of the polymerization mixture.
US08188200B2	Process for preparation of polyolefins via living coordinative chain transfer polymerization Disclosed is a method of producing a polyolefin composition comprising contacting a metallocene pre-catalyst, co-catalyst, and a stoichiometric excess of a metal alkyl; adding a first olefin monomer; and polymerizing the first monomer for a time sufficient to form the polyolefin. The method allows for the use of minimum amounts of activating co-catalyst and metallocene pre-catalyst. Also disclosed is a method of producing a block polyolefin composition comprising contacting a metallocene pre-catalyst, a co-catalyst, and a stoichiometric excess of a metal alkyl; adding a first olefin monomer; polymerizing the first monomer for a time sufficient to form the polyolefin; adding a second monomer; and polymerizing the second olefin monomer for a time sufficient to form said block polyolefin composition. Also disclosed are amorphous atactic polymer and copolymer compositions made according to the present invention.
US08188197B2	Method for producing a polymer The present invention relates to a method for performing a polymerization process in a stirred reactor, wherein a critical time window is determined by means of a monitor of at least one polymerization process parameter and an associated process window, and when a critical time window is present, an adaptation of process conditions is made in order to configure the polymerization process to conform to the process window.
US08188196B2	Two-component polyurethane clear coat kit system A two-component polyurethane clear coat kit system consisting of: (1) a binder component having a solids content of 42 to 50 wt.-% comprising at least one hydroxyl-functional binder and a volatile organic content of 50 to 58 wt.-%, and (2) a polyisocyanate crosslinker component having a solids content of 66 to 70 wt.-% and a volatile organic content of 30 to 34 wt.-%, wherein the solids content of the polyisocyanate crosslinker component comprises a free polyisocyanate solids content consisting of 75 to 100 wt.-% of at least one polyisocyanate of the 1,6-hexane diisocyanate isocyanurate type and of 0 to 25 wt.-% of at least one polyisocyanate of the isophorone diisocyanate isocyanurate type, wherein the sum of the respective wt.-% in each case totals 100 wt.-%.
US08188195B2	Polymers functionalized with nitroso compounds A method for preparing a functionalized polymer, the method comprising the steps of: (i) polymerizing monomer with a coordination catalyst to form a reactive polymer; and (ii) reacting the reactive polymer with a nitroso compound.
US08188194B2	Adhesive for polarizing plate and polarizing plate having adhesive layer An adhesive composition for polarizing plates in which an acrylic polymer, a tin compound having a dialkyl group and serving as a cross-linking accelerator and an isocyanate cross-linker are dissolved in an organic solvent, the acrylic polymer being formed by copolymerization of monomers containing an alkyl (meth)acrylate, a hydroxyl group containing monomer and/or a carboxyl group containing monomer, wherein preferably, a solution containing 30% by weight of the acrylic polymer which constitutes the adhesive composition, dissolved in 70% by weight of ethyl acetate has a viscosity in the range of 0.5 to 10.0 Pa·s measured at 23° C., and the acrylic polymer has a weight-average molecular weight in the range of 300,000 to 700,000.
US08188191B2	Polyolefin polymer containing vinyl groups at both ends and composition thereof The present invention is a polyolefin polymer containing vinyl groups at both ends thereof, and a composition and a molded product containing the polymer, wherein the polymer contains a constitutional unit derived from at least one selected from the group consisting of ethylene (a), an α-olefin (b) having 3 to 20 carbon atoms, and a cyclic olefin (c), and (1) a ratio of terminal vinylation is 70% or more relative to all of both ends of molecular chains, and (2) an intrinsic viscosity [η] is in the range of 0.01 to 10 dl/g as measured in a decalin solution at 135° C. The polymer of the present invention may be molded by a LIM molding, an injection molding, a transfer molding, a compression molding, and the like, and is excellent in acid resistance, gas permeation resistance, hydrolysis resistance, and dynamic fatigue resistance. From the polymer, a thermoplastic resin composition and a crosslinkable resin composition, and a crosslinked composition having excellent mechanical characteristics are obtained.
US08188186B2	Golf ball An object of the present invention is to provide a golf ball having excellent durability and flight distance. The present invention provides a golf ball comprising: a core consisting of a center and one or more intermediate layers covering the center; and a cover covering the core, wherein, at least one piece or one layer of said intermediate layers is formed from a highly elastic intermediate layer composition that contains a highly elastic resin (A) having a flexural modulus in a range from 700 MPa to 5000 MPa and an ionomer resin (B) having a flexural modulus in a range from 150 MPa to 1000 MPa in an amount ratio ((A)/(B)) of the highly elastic resin (A) to the ionomer resin (B) being (20 mass % to 80 mass %)/(80 mass % to 20 mass %) (the total is 100 mass %).
US08188185B2	Biodegradable packaging film A biodegradable packaging film is provided. The film is formed from a blend that contains a thermoplastic starch and polylactic acid. Starch is a relatively inexpensive natural polymer that is also renewable and biodegradable. Polylactic acid is likewise an inexpensive synthetic polymer that is biodegradable and renewable, yet also capable of providing increased tensile strength to the film. Although providing a good combination of biodegradability/renewability and increased tensile strength, the polylactic acid is also relatively rigid and can result in films having a relatively high stiffness (e.g., high modulus of elasticity) and low ductility. While more ductile than polylactic acid, the thermoplastic starch is often difficult to melt process in film forming processes and very sensitive to moisture and water vapor, reducing its ability to be used as a stand alone packaging film. In an effort to counteract the effect of such polymers, an aliphatic-aromatic copolyester is also employed in the blend of the present invention. While such copolyesters are biodegradable, they also possess the melt properties and ductility that lend them well to the formation of films. Although the combination of these polymers may achieve a good balance between biodegradability/renewability, high tensile strength, and good ductility (e.g., high peak elongation), it is still often difficult to achieve a precise set of mechanical properties as desired for packaging films. In this regard, the blend also contains a filler. Due to its rigid nature, the amount of the filler may be readily adjusted to fine tune the blend to the desired degree of ductility (e.g., peak elongation) and stiffness (e.g., modulus of elasticity).
US08188182B2	Ion-conductive thermoplastic compositions for electrochromic glazing The invention relates to ion-conductive thermoplastic compositions consisting of a partially acetalated polyvinyl alcohol, at least one support electrolyte and at least one softener, the partially acetalated polyvinyl alcohol containing two different acetal units. The invention also relates to electrochromic laminated glass systems produced using the ion-conductive compositions and to a method for producing said systems.
US08188176B2	Fluorine-containing elastomer Disclosed is a fluorine-containing elastomer having a copolymerization composition containing (A) 72.8 to 74.0 mol % of tetrafluoroethylene, (B) 26.8 to 24.0 mol % of perfluoro(lower alkyl vinyl ether) or perfluoro(lower alkoxy-lower alkyl vinyl ether), and (C) 0.2 to 3.0 mol % of a perfluoro unsaturated nitrile compound, and having a Mooney viscosity ML1+10(121° C.) of 70 to 115. The fluorine-containing elastomer is compounded with a bisamidoxime compound, which is used as a vulcanizing agent, in an amount of 0.2 to 5 parts by weight based on 100 parts by weight of the fluorine-containing elastomer to form a fluorine-containing elastomer composition. The vulcanizate of the composition, even when used under plasma irradiation conditions or at temperatures as high as 300° C., can prevent weight loss caused by plasma irradiation and exhibits excellent heat resistance at temperatures as high as 300° C. or more.
US08188173B2	Polyvinyl acetal powder coating material The present invention provides a polyvinyl acetal powder coating material capable of forming a coating film having a highly smooth surface, being less susceptible to yellowing when exposed to heat, and being suitable for working such as bending of a coated article. The present invention is a polyvinyl acetal powder coating material including: a polyvinyl acetal resin; and 0.02 to 5% by weight of an antioxidant relative to the polyvinyl acetal resin. The antioxidant has a molecular weight of 380 to 1000 and a melting point of 80 to 230° C. It is preferable that the molecular weight of the antioxidant be 400 to 1000.
US08188171B2	Polyisocyanate composition having improved impact-proof properties The invention relates to the use of additived (poly)isocyanate compositions for producing coatings, especially paints or varnishes for car bodywork parts, said compositions having excellent impact-resistant properties, especially grit-resistant properties.
US08188170B2	Polymers with low gel content and enhanced gas-fading A polymer stabilizing composition comprising a sterically hindered phenol and a phosphite that provides low gel content and enhanced resistance to gas-fading. The stabilizer composition is particular useful for stabilizing polyethylene homopolymers and copolymers, such as linear low density polyethylenes produced from metallocene catalyst. The sterically hindered phenol is selected from the group consisting of 1,3,5-tris-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)isocyanurate, 1,3,5-tris-(3,5-dicyclohexyl-4-hydroxybenzyl)isocyanurate, 1,3,5-tris-(3,5-di-tert-butyl-4-hydroxybenzyl)isocyanurate,1,3,5-tris(4-t-butyl-3-hydroxy-2,6-dimethylbenzyl)-1,3,5-Triazine-2,4,6-(1H,3H,5H)-trione, and 1,3,5-tris-(3,5-di-tert-butyl-4-hydroxybenzyl)-2,4,6-trimethylbenzene. The phosphite preferably is a liquid phosphite composition comprising two or more alkylated aryl phosphites.
US08188166B2	Unsaturated polyester resin compositions with improved weatherability Unsaturated polyester resin compositions with improved weathering characteristics are presented. Further, the manufacture of these unsaturated polyester resin compositions and their potential applications are presented.
US08188164B2	Cellulose-based masterbatch with improved breaking elongation, application thereof and method for preparing the same Disclosed herein is a thermoplastic cellulosic composition for preparing a cellulose-based masterbatch and/or a fiber with an improved breaking elongation. In one example, the thermoplastic cellulosic composition includes an esterified cellulose present in a range of about 77 wt % to about 95 wt %, polyethylene glycol present in a range of about 4.5 wt % to about 15 wt %, a bifunctional reactant present in a range of about 0.01 wt % to about 3 wt %, an initiator present in a range of about 0.01 wt % to about 0.15 wt %, and a dispersing agent present in a range of about 0.01 wt % to about 5 wt %.
US08188160B2	Ink set for inkjet recording, image recording method and image recording apparatus The ink set for inkjet recording includes: a water-based ink containing pigment particles and 10 to 25 wt % of water-soluble high-boiling-point organic solvent having an SP value of not higher than 30; and a treatment liquid containing a fluidity reducing agent which reduces fluidity of the pigment particles by making contact with the water-based ink, and 10 to 25 wt % of water-soluble high-boiling-point organic solvent having an SP value of not higher than 30.
US08188159B2	Environmentally friendly additives for inkjet inks An inkjet ink comprising polymeric fluoro-polymeric additives providing enhanced pen and print quality performance.
US08188158B2	Polymer based ink formulation The invention provides an ink formulation comprising a polymer associated self-dispersed colorant. The polymer has an alkyl amino end functional group that is chemically associated by electron donation/acceptation and hydrogen bonded to surface functional groups of the colorant particles. The modified self-dispersed colorant shows improved printing quality.
US08188156B2	Polyol composition, foaming composition and polyurethane foam Disclosed is a polyol composition containing an aromatic polyester polyol having a hydroxyl number of 300-500 mgKOH/g and an average number of functional groups of 2.0-2.5, a medium-chain polyether polyol having a hydroxyl number of 100-250 mgKOH/g and an average number of functional groups of 2.0-4.0 and composed of a polyoxypropylene unit, and a long-chain polyether polyol having a hydroxyl number of 15-40 mgKOH/g, an average number of functional groups of 2.0-4.0 and an oxyethylene content of not more than 14% by weight and mainly composed of a polyoxypropylene unit.
US08188155B2	Rubber de-vulcanisation The present invention relates to a method for preferentially breaking cross-links in a vulcanized rubber, thereby de-vulcanizing the rubber, by the use of a supercritical fluid, such as carbon dioxide The supercritical fluid causes swelling of the said vulcanized rubber material, wherein the time of swelling is not more than 50% of the time required for full volume equilibrium swelling of the rubber in said supercritical fluid and the swelling is followed by a rapid reduction of the supercritical fluid pressure The cross links (3) become fully extended and under strain to hold the internal pressures caused by the solvent swelling affect of the supercritical gas When equilibrium swell has been achieved, the pressure within the processing vessel is rapidly dropped to a predetermined level causing a degassing and expansion of the supercritical fluid that has been absorbed within the vulcanized rubber The resulting three dimensional separation of the rubber molecules will put a further rapid strain on the cross links, causing them to break (7), thereby giving the affect of de-vulcanization.
US08188152B2	2-aminoalcohols for the treatment of neurodegenerative diseases Use of a compound for the manufacture of a medicament for use in therapy of a neurodegenerative condition, wherein the compound is of formula (I): wherein R1 is CHR4—OR5 or CHR4—SR5, or aryl or heteroaryi optionally substituted with one or more groups R6; R2 is alkyl or is part of a ring with R3; R3 is H, alkyl or CH2 (when forming part of a ring with R2); R4 is H or alkyl or is part of a ring with R 5; R5 is aryl or heteroaryi optionally substituted with R7; each R6 is independently alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2alkyl, CONH2, SOMe, SO2NH2, Salkyl, CH2SO2alkyl or OCONalkyl2; R7 is R8 or (CH2)nOR8, R9, CF3, OH, OR9, OCOR9, COR9, COOR9, CONH2, CH2CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHCONHR7, NHCON(R9)2, NHCOR9, NHCOaryl, NHSO2Me, CONH2, SMe, SOMe or SO2NH2; R8 is (CH2)nOR9, (CH)nOR9, (CH2)nCOOR9 or (CH2)nCOaryl; R9 is alkyl or cycloalkyl; and n is 1 to 4; or a salt thereof.
US08188150B2	Use of beta-aminoalcohols in the treatment of inflammatory disorders and pain A compound for therapeutic use, of the formula (I), wherein R1 is aryl or heteroaryl optionally substituted with R5; R2 is H, alkyl or CH2OH or forms part of a ring with R4; R3 is H, alkyl or CH2OH or forms part of a ring with R4; R4 is H, alkyl or (when forming part of a ring with R2 or R3) CH2; and R5 is alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2Me, CONH2, or SOMe; or a salt thereof.
US08188146B2	Highly purified ethyl EPA and other EPA derivatives A pharmaceutical preparation comprising EPA in an appropriately assimilable form where of all the fatty acids present in the preparation at least 90%, and preferably at least 95%, is in the form of EPA and where less than 5%, and preferably less than 3%, is in the form of DHA is provided.
US08188145B2	Synthetic lactone formulations and method of use Natural and synthetic compounds having a lactone structure methods for alleviation of pain, especially pain associated with disorders such as melanoma, leukemia, breast cancer, lung cancer, ovarian cancer, colon cancer, esophagus cancer, liver cancer, and lymphatic cancer. Initial studies have shown that patients can be taken off of morphine when the preferred alpha-methylene-gamma-butyrolactone is administered in a dosage of between 60 and 120 mg/day intramuscularly.
US08188134B2	Thiophene-carboxamides useful as inhibitors of protein kinases The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
US08188129B2	(−)-enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione A novel (−)-enantiomer of 2-[2-(1-chloro-cyclopropyl)-3-(2-chloro-phenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione of the formula a process for preparing this novel active compound and its use as microbicide in crop protection and in the protection of materials.
US08188128B2	Opioid receptor subtype-selective agents Opioid receptor compounds and pharmaceutical compositions thereof are presented. Also presented are methods for treating a condition mediated by an opioid receptor by administering an effective amount of the opioid receptor compound to a patient in need thereof.
US08188127B2	Microbicidal composition Synergistic microbicidal compositions containing N-methyl-1,2-benzisothiazolin-3-one.
US08188126B2	Imidazolic compounds and use thereof as alpha-2 adrenergic receptors The invention provides methods of treating a memory deficiency in a subject in need of such treatment, where the methods comprise administering to a subject an effective amount of a compound of formula (1): wherein: R1 is hydrogen, fluorine or a methoxyl group, R1 being in position 2, 3, 4 or 5 of the aromatic carbocycle; R2 is hydrogen or a methyl group; R3 is hydrogen, a methyl group or an ethyl group; and their pharmaceutically acceptable acid addition salt as well as the isomers and the tautomers thereof. The memory deficiency may be correlated with a memory deficiency induced by scopolamine.
US08188121B2	Substituted pyridines as antiparasitic AZA teraryl compounds Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. The compounds include those of Formula (III): wherein one of A1, Y1, and Z1 is N; Ar1 is phenylene; and Ar3 is a nitrogen-containing aromatic group. An exemplary compound of Formula (III) is:
US08188120B2	Lactam-containing compounds and derivatives thereof as factor Xa inhibitors The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4 I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
US08188119B2	Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same The present invention provides an antifungal agent which has excellent antifungal action, and which is also excellent in terms of its properties, and in particular its solubility in water and safety. The present invention discloses a compound represented by the following formula (I) or a salt thereof. wherein R1, R2, R3, R4, A, X, Y, and Z are defined in the specification.
US08188117B2	Piperidinyl-substituted isoquinolone derivatives The invention relates to 6-piperidinyl-substituted isoquinolone derivatives of the formula (I) or isoquinoline derivatives of the formula (I′) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
US08188112B2	Naphthalamide derivatives having antiproliferative activity The invention relates to compounds for use in medicine. The compounds are of general formula (I) as disclosed herein and the pharmaceutically acceptable salts, individual isomers and mixtures of isomers thereof, wherein X, X′ and X″ are independently O or S; Z is N or P; R3 is optional and is selected from the group consisting of optionally substituted C1-8 alkyl, optionally substituted C2-6alkenyl, optionally substituted C2-6 alkynyl, optionally substituted C1-6 alkoxy, optionally substituted C1-6 thioalkyl, optionally substituted C5-10 aryl, optionally substituted C6-11 alkylaryl, optionally substituted C1-6 alkylamino, optionally substituted C1-6 alkylcarbonyl, optionally substituted C1-6 alkylsulfonamino, optionally substituted (C1-C6)alkylsulfinyl, optionally substituted C1-6 alkylcarbonylamino, optionally substituted hetero(C4-C10)aryl, hydroxyl, halogen, cyano, nitro, amino, formyl, and thiol; R1, R2, R4, R5, R6, R7, R8, R9, and R10 are independently selected from the group consisting of hydrogen, optionally substituted C1-8 alkyl, optionally substituted C2-6 alkenyl, optionally substituted C2-6 alkynyl, optionally substituted C1-6 alkoxy, optionally substituted C1-6 thioalkyl, optionally substituted C5-10 aryl, optionally substituted C6-11 alkylaryl, optionally substituted C1-6 alkylamino, optionally substituted C1-6 alkylcarbonyl, optionally substituted C1-6 alkylsulfonamino, optionally substituted (C1-C6)alkylsulfinyl, optionally substituted C1-6 alkylcarbonylamino, optionally substituted hetero(C4-C10)aryl, hydroxyl, halogen, cyano, nitro, amino, formyl, and thiol; and - - - indicates an optional double bond.
US08188108B2	Pharmaceutical composition A pharmaceutical composition comprising an analgesic or analgesic combination and a stool softener is disclosed. The analgesic is selected from morphine, meperidine, fentanyl, hydromorphone, oxymorphone, oxycodone, hydrocodone, methadone, propoxyphene, pentazocine, levorphanol, codeine, acetaminophen and combinations of these analgesics. The composition is formulated for oral administration as a liquid or solid dosage form for immediate, slow, delayed or sustained-release characteristics.
US08188102B2	Amide derivative for inhibiting the growth of cancer cells The present invention provides a novel amide derivative of formula (I) and a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same as an active ingredient.
US08188100B2	Adenosine derivatives as A2A receptor agonists A compound of formula (I), or stereoisomers or pharmaceutically acceptable salts thereof, formula (1), or stereoisomers or pharmaceutically acceptable salts thereof, wherein A, U1, U2, R1a, R1b, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
US08188098B2	GPR119 receptor agonists Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
US08188096B2	Protein kinase targeted therapeutics The present invention relates to compositions and methods useful in treating diseases and disorders related to protein kinases. In particular, the present invention relates to compositions and methods useful for targeting protein kinases related to mitogen activated protein kinase (MAPK) pathways (e.g., p38 MAPK, JNK, ERK, and upstream and downstream protein kinases) and/or casein kinase (CK) pathways (e.g., CK1δ, and upstream and downstream protein kinases), and diseases and disorders related to MAPK pathways (e.g., p38 MAPK, JNK, ERK, and upstream and downstream protein kinases) and/or CK pathways (e.g., CK1δ, and upstream and downstream protein kinases).
US08188094B2	Inhibitors of glutaminyl cyclase Compounds of formula (I), combinations and uses thereof for disease therapy, or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof wherein: A represents and B, R1, R2, R3, R4, R5, R6, R7, Y and Z are as defined throughout the description and the claims.
US08188093B2	Pyrazinecarboxamide derivatives as HDL-cholesterol raising agents The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
US08188091B2	Tetrahydroquinazoline compounds and their use in preparing medicaments for treating and preventing virosis The present invention relates to a compound of formula (I) or isomers thereof, or pharmaceutically acceptable salts or hydrates thereof. The present invention further relates to processes for the preparation of the compounds of formula (I) and optical isomers, and to the use of the compounds of formula (I), or isomers thereof, or pharmaceutically acceptable salts or hydrates thereof as medicaments, in particular as medicaments for the treatment and prevention of Hepatitis B.
US08188089B2	Tylophorine analogs as antitumor agents Compounds of Formula I are described: preferably subject to the proviso that either (a) R2 and R3 together form —O—CH(R10)—O—, or (b) R5 and R6 together form —O—CH(R10)—O—, wherein R10 is H, halo, or loweralkyl. Pharmaceutical salts, formulations, and methods of using the same in the treatment of cancer are also described.
US08188077B2	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
US08188075B2	Triazole compounds that modulate HSP90 activity The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of treating or inhibiting angiogenesis in a subject in need thereof and methods for blocking, occluding, or otherwise disrupting blood flow in neo vasculature, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
US08188074B2	Biologically active methylene blue derivatives The present invention relates to a composition which includes a moiety of formula wherein R1, R2, R3 and R4 each represent n-pentyl, and to a method of sterilizing a su fluid using same.
US08188072B2	Benzodiazepinone compounds useful in the treatment of skin conditions The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.
US08188071B2	Amino substituted pyridines as potent kinase inhibitors The present invention relates to compounds useful as inhibitors of protein kinase of the following structural formula: The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
US08188070B2	Method of treating neurological diseases and disorders The present invention provides methods for treating neurological diseases and disorders. Compounds that replace or enhance the function of SMN or alleviate or reduce a phenotype of cells with low SMN protein levels are provided. Screening methods and kits for identifying such compounds also are provided.
US08188065B2	Boldine compounds for promoting bone growth The present invention provides a method of promoting bone growth in a subject in need thereof, by administering to the subject a therapeutically effective amount of a compound of Formula I. The present invention also provides methods for the treatment of renal disease and cancer.
US08188062B2	Delivery of DNA or RNA via gap junctions from host cells to target cells and a cell-based delivery system for antisense or siRNA A method of delivering an oligonucleotide or a plasmid expressing an oligonucleotide into a target cell comprises introducing an oligonucleotide into a donor cell, particularly a stem cell, and contacting the target cell with the donor cell under conditions permitting the donor cell to form a gap junction with the target cell, whereby the oligonucleotide or a product of the oligonucleotide is delivered into the target cell from the donor cell.
US08188058B2	Use of toll-like receptor-9 agonists, toll-like receptor-4 antagonists, and/or nuclear oligomerization domain-2 agonists for the treatment or prevention of toll-like receptor-4-associated disorders The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.
US08188057B2	Modulation of 11beta-hydroxysteriod dehydrogenase 1 expression for the treatment of ocular diseases The invention relates to siNA compositions and methods for the treatment of eye conditions wherein the siNA compound capable of inhibiting the expression of 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD1).
US08188055B2	Inactivators of O6-alkylguanine-DNA alkyltransferase Disclosed are compounds that are AGT inactivators that include a folate residue, e.g., a compound of formula (I), wherein X1, X2, R1, and R2 are as described herein. Also disclosed is a pharmaceutical composition comprising a compound of the invention and a pharmaceutically acceptable carrier. Also disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells and inactivating AGT in a tumor cell. The methods comprise, inter alia, administering a compound or pharmaceutically acceptable salt of formula (I).
US08188051B2	Metadherin polypeptides, encoding nucleic acids and methods of use Metadherin, a protein that controls metastasis, and variants of metadherin are described. DNA sequences encoding the same and methods of production are described. Therapies involving the application of metadherin, binding agents that bind to metadherin, such as antibodies, and expression modulating agents, such as siRNA, are described. The use of metadherin or metadherin variants for delivering desired substances to particular lung tissue is described. A method of diagnosing metastatic cells based on the presence of metadherin is described.
US08188050B2	Pharmaceutical and/or cosmetic composition containing peptides The present invention concerns the use of peptide fragments of the protein SLC24A5 as active agents designed to induce, increase, or restore the synthesis of melanin in the melanocytes of the epidermis or of the pilar bulb, alone or in association with at least one other active agent, in a cosmetic composition or for the preparation of a pharmaceutical or particularly dermatological composition. The invention is also related to any composition containing the active agents.
US08188042B1	Nanoparticles for protein drug delivery The invention discloses bioactive nanoparticles composed of chitosan, poly-glutamic acid, and diethylenetriaminepentaacetic acid for use in radionuclide decorporation during radiological emergency. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
US08188040B2	FGF21 mutants and uses thereof The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.
US08188038B2	Osteogenic compositions containing a coloring agent An osteogenic composition is provided for implantation at or near a target tissue site beneath the skin, the osteogenic composition comprising a growth factor and a coloring agent, wherein the coloring agent imparts color to the growth factor to allow the user to see the growth factor at or near the target tissue site. In some embodiments, a method is provided for accelerating bone repair, the method comprising mixing bone morphogenic protein-2 and a coloring agent to form a mixture; applying the mixture to a surface of a porous collagen matrix, wherein the coloring agent allows the user to see bone morphogenic protein-2 distribution on or in the porous collagen matrix; and implanting the porous collagen matrix at or near a target tissue site in need of bone repair.
US08188034B2	Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation The present invention provides compositions of saratin and methods of use thereof. One aspect of the invention is a method of prevention or mitigation of the development of adhesions, keloids and scars. The adhesions, keloids and scars can be due to surgery, such as plastic surgery or orthopedic surgery, or can be pre-existing scars. Another aspect of the invention is a method for treatment of flexor tendon injuries.
US08188031B2	Reusable antistatic dryer products and methods for fabricating the same Dryer products that impart antistatic properties to textiles and methods for fabricating such dryer products are provided. In one exemplary embodiment, a dryer product comprises a water-insoluble, moisture-permeable, enclosed container and a desiccant within the water-insoluble, moisture-permeable, enclosed container. The desiccant is adapted to impart antistatic properties to the textiles during a drying cycle. In another exemplary embodiment, a method for fabricating a reusable antistatic dryer product comprises the steps of providing a desiccant adapted to absorb moisture and be solubilized in the moisture, depositing the desiccant in a water-insoluble, moisture-permeable container, and enclosing the desiccant within the water-insoluble, moisture-permeable container.
US08188030B2	Fabric softener compositions and methods of manufacture thereof Disclosed herein is a fabric softener composition comprising a fabric softener active compound that comprises a quarternary ammonium salt and/or an imidazolinium salt, and a ketal adduct of formula (12) wherein R1 is C1-6 alkyl, R2 is hydrogen or C1-3 alkyl, each R3 and R4, is independently hydrogen or C1-6 alkyl, each R5 and R6 is independently hydrogen or C1-6 alkyl, or hydroxymethyl, R7 is hydrogen, C1-6 alkyl, C1-6 alkyl substituted with up to four OR8 groups wherein R8 is hydrogen, C1-6 alkyl, or acetyl, a is 0-3, and b is 0-1.
US08188029B2	Hydrophilic polyurethane foam articles comprising an antimicrobial compound Foamed polyurethane articles, such as a sponges, sheets, tapes or ribbons, blocks or other molded, extruded or cast article which foamed polyurethane articles exhibit an antimicrobial benefit and are particularly useful in the formation of cleaning articles. Processes for the manufacture of such cleaning articles based on hydrophilic polyurethane foams exhibit an antimicrobial benefit and their use are also described.
US08188026B2	Liquid treatment composition According to the present invention there is provided a pearlescent liquid treatment composition suitable for use as a laundry or hard surface cleaning composition comprising a rheology modifier providing a pouring viscosity at 20 sec−1 of from 50 to 700 cps, a viscosity at constant low stress of 0.1 Pa which is at least 300 cps, preferably 500 cps and a pearlescent agent, said pearlescent agent having D0.99 volume particle size of less than 60 μm.
US08188025B2	Sanitizing and cleaning composition and its use for sanitizing and/or cleaning hard surfaces The present invention relates to acidic sanitizing and/or cleaning compositions comprising a specific quaternary antimicrobial system consisting of C1-C4 hydroxyalkyl carboxylic acids, C5-C18 alkyl monocarboxylic acids, unsubstituted or substituted, saturated or unsaturated C4-dicarboxylic acids and additional inorganic or organic acids. The compositions of the present invention can be present in the form of concentrates and in the form of diluted use solutions. They can be used in a process for sanitizing and/or cleaning hard surfaces, preferably in a cleaning-in-place (CIP) and/or sanitize-in-place (SIP) process for cleaning and/or sanitizing plants in the food, dairy, beverage, brewery and soft drink industries.
US08188023B2	4-alkyl cyclohexanepropanal compounds and their use in perfume compositions The present invention is directed to novel 4-alkyl cyclohexanepropanal compounds and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of the novel compounds.
US08188022B2	Multilayer fragrance encapsulation comprising kappa carrageenan Disclosed herein is a fragrance composition and a method for making the same having a fragrance particulate and a viscoelastic gel; where the composition has enhanced fragrance retention throughout the processing of the composition.
US08188018B2	Lubricating oil composition A lubricating oil composition for use in oil-impregnated sintered bearings together with a resin member having C═C bonds or C═O groups in the molecules, which comprises a base oil comprising a synthetic hydrocarbon oil as the main component, and 0.1-30% by weight of an ester-based oil on the basis of total composition, and free from zinc dialkyldithiophosphate and molybdenum dialkyldithiocarbamate, where the synthetic hydrocarbon oil as the main component of the base oil has substantially no adverse effect on resin, can minimize an adverse effect on various metal species of sintered materials by suppressing a mixing amount of a wear inhibitor or an extreme pressure agent to a minimum, without deteriorating a good lubricability required for the lubricating oil in oil-impregnated sintered bearings.
US08188017B2	Organic molybdenum compounds and oil compositions containing the same The present invention provides novel organic molybdenum compounds, the use thereof as friction-modifiers and lubricating compositions which contain said compounds.The organic molybdenum compounds can be represented by the general formula (1) which is indicated below, wherein A1 and A2 are heterocyclic rings which may have substituent groups.
US08188009B2	4-(3-aminobenzoyl)-5-cyclopropylisoxazoles effective as herbicides 4-(3-Aminobenzoyl)-5-cyclopropylisoxazoles of the formula (I) are described as herbicides. In this formula (I), A, X, Y and Z are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen.
US08188008B2	Herbicidally and insecticidally active 4-phenyl-substituted pyridazinones The invention describes phenyl-substituted pyridazinones of the formula (I) as herbicides and insecticides. In this formula (I), A, B, G, X, Y and Z are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen, nitro and cyano.
US08187998B2	Document and method of manufacturing a document A document has a carrier layer and at least a functional layer. The functional layer is provided with a content of bacteriorhodopsin as color pigment and, when the document is printed generating an essentially irreversible color change in the area of the bacteriorhodopsin by a supply of energy.
US08187997B2	Low metal loaded, catalyst compositions including acidic mixed metal oxide as support The invention provides a catalyst composition composed of a support portion and a catalyst portion. The support portion includes an acidic mixed metal oxide including a transitional alumina and a second metal oxide. The transitional alumina can comprise delta or theta alumina, in combination with other transitional phases, or an alpha or gamma alumina. The second metal oxide has a weight percentage that is less than the weight percentage of alumina. The catalyst portion is 25 weight percent or less of the catalyst composition and is composed of nickel and rhenium. The catalyst portion includes nickel in an amount in the range of 2 to 20 weight percent, based upon total catalyst composition weight, and there is no boron in the catalyst portion.
US08187996B2	Exhaust gas-purifying catalyst An object of the present invention is to provide an exhaust gas-purifying catalyst containing a composite oxide catalyst and a refractory support and being less prone to cause a decrease in its activity even when used at high temperatures in an atmosphere with high oxygen concentration. An exhaust gas-purifying catalyst includes a composite oxide catalyst containing rare-earth element, alkaline-earth element and precious metal, a part of the rare-earth element and a part of the alkaline-earth element forming composite oxide, and the composite oxide and a part of the precious metal forming solid solution, and a refractory support supporting the composite oxide catalyst and including at least one of a first composite oxide represented by a general formula AB2O4, a second composite oxide having perovskite structure represented by a general formula LMO3, and a third composite oxide having pyrochlore structure represented by a general formula X2Y2O7.
US08187995B2	Cerium/zirconium-base composite oxide, method for producing the same, oxygen storage/release component using said cerium-zirconium-base composite oxide, exhaust gas purification catalyst, and exhaust gas purification method using the same This invention relates to a cerium-zirconium-base composite oxide, which is useful, e.g., for the purification of exhaust gas discharged from combustion engines such as internal combustion engines and boilers and can release a high level of oxygen in a low temperature region, a method for producing the same, an oxygen storage/release component using the same, an exhaust gas purification catalyst, and an exhaust gas purification method. The cerium-zirconium-base composite oxide satisfies requirements (1) that the oxygen release initiation temperature is 380° C. or below, (2) that the oxygen release amount is not less than 485 μmol/g, and further (3) that the oxygen release amount at 400° C. is not less than 15 μmol/g. The cerium-zirconium-base composite oxide can be produced, for example, by mixing a starting material for cerium and a starting material for zirconium at a predetermined mixing ratio together, melting the starting material mixture at a temperature at or above the melting point, then cooling the melt to form an ingot, then optionally grinding the ingot to prepare powder, subsequently removing strain within powder crystal grains under heating, and then grinding to a further fine state.
US08187990B2	Hollow piece for producing a sintered refractory product exhibiting improved bubbling behaviour A green part, a region of a refractory furnace or a hollow piece for producing a sintered refractory has the following mean mineral chemical composition in weight percent based of mineral oxides: 40%≦Al2O3≦94%, 0%≦ZrO2≦41%, 2%≦SiO2≦22%, 1%
US08187984B2	Temperature responsive smart textile A textile fabric includes a smooth surface with one or more regions having coating material exhibiting thermal expansion or contraction in response to change in temperature, adjusting insulation performance of the textile fabric in response to ambient conditions.
US08187982B2	Manufacture method for photovoltaic module The invention permits a plurality of strips of resin adhesive film having a desired width and unwound from a single feeding reel to be simultaneously pasted on a solar cell. For this purpose, the invention comprises the steps of: unwinding a resin adhesive film sheet from a reel on which the resin adhesive film sheet is wound; splitting the unwound resin adhesive film into two or more film strips in correspondence to lengths of wiring material to bond; pasting the strips of resin adhesive film on an electrode of the solar cell; and placing the individual lengths of wiring material on the electrode of the solar cell having the plural strips of resin adhesive film pasted thereon and thermally setting the resin adhesive film by heating so as to fix together the electrode of the solar cell and the wiring material.
US08187979B2	Workpiece patterning with plasma sheath modulation Methods to texture or fabricate workpieces are disclosed. The workpiece may be, for example, a solar cell. This texturing may involve etching or localized sputtering using a plasma where a shape of a boundary between the plasma and the plasma sheath is modified with an insulating modifier. The workpiece may be rotated in between etching or sputtering steps to form pyramids. Regions of the workpiece also may be etched or sputtered with ions formed from a plasma adjusted by an insulating modifier and doped. A metal layer may be formed on these doped regions.
US08187978B2	Method of forming openings in a semiconductor device and semiconductor device A method of forming openings to a layer of a semiconductor device comprises forming a dielectric layer over the layer of the semiconductor device, forming a main mask over the dielectric layer, the main mask comprising a plurality of main mask openings arranged in a regular pattern extending over the dielectric layer, using a selector mask to select some of the plurality of main mask openings and removing portions of the dielectric layer through the selected some of the plurality of main mask openings to provide openings extending through the dielectric layer to the layer.
US08187977B2	Automatic gain control Methods and apparatus for automatic gain control. A film on a substrate is polished by a chemical mechanical polisher that includes a polishing pad and an in-situ monitoring system. The polishing pad includes a first portion, and the in-situ monitoring system includes a light source and a light detector. The light source emits light, and light emitted from the light source is directed through the first portion and to a surface of the film being polished. Light reflecting from the surface of the film being polished and passing through the first portion is received at the light detector. An electronic signal is generated based on the light received at the light detector. When the electronic signal is evaluated not to satisfy one or more constraints, a gain for the light detector is adjusted so that the electronic signal would satisfy the one or more constraints.
US08187976B2	Stable P-type semiconducting behaviour in Li and Ni codoped ZnO A method is provided for growing a stable p-type ZnO thin film with low resistivity and high mobility. The method includes providing an n-type Li—Ni co-doped ZnO target in a chamber, providing a substrate in the chamber, and ablating the target to form the thin film on the substrate.
US08187969B2	Method for manufacturing semiconductor device A method for manufacturing a semiconductor device includes the steps of forming conductive patterns on a substrate; forming an interlayer dielectric between the conductive patterns; defining contact holes in the interlayer dielectric to expose portions of the substrate between the conductive patterns; forming a first conductive layer on a surface including the contact holes; forming contact plugs in such a way as to be isolated in the respective contact holes, by etching a surface of the first conductive layer to expose upper end surfaces of the conductive patterns; etching a partial thickness of the conductive patterns so that the upper end surfaces of the conductive patterns are lower than an upper end surface of the interlayer dielectric; and forming an insulation layer on the resultant structure.
US08187968B2	Methods of post-contact back end of line through-hole via integration Presented are methods of fabricating three-dimensional integrated circuits that include post-contact back end of line through-hole via integration for the three-dimensional integrated circuits. Another aspect of the present invention includes three-dimensional integrated circuits fabricated according to methods of the present invention.
US08187967B2	Method of manufacturing a non-volatile memory device A method of manufacturing a non-volatile memory device providing a semiconductor layer in which a cell region and a peripheral region are defined, sequentially forming a first insulating layer, a first conductive layer, a second insulating layer, and a second conductive layer on the cell region and the peripheral region, forming a trench for exposing a portion of the first conductive layer of the peripheral region, wherein the trench is formed by removing portions of the second conductive layer and the second insulating layer in the peripheral region, performing a trimming operation for removing portions of the second conductive layer and the second insulating layer of the cell region, forming a spacer on a side surface of the trench, and forming a silicide layer that is electrically connected to the first conductive layer, wherein the silicide layer is formed by performing a silicidation process on the spacer.
US08187960B2	Method of joining and method of fabricating an organic light emitting diode display device using the same A method of joining a flexible layer and a support includes forming a first metal layer on one surface of the flexible layer, forming a second metal layer on one surface of the support, cleaning the first metal layer and the second metal layer, and joining the first metal layer to the second metal layer, such that the first metal layer is between the flexible layer and the second metal layer.
US08187957B2	Field-effect transistor and method for fabricating the same A field-effect transistor that increases the operation speeds of complementary field-effect transistors. Each of an nMOSFET and a pMODFET has a Ge channel and source and drain regions formed of an NiGe layer. The height of Schottky barriers formed at a junction between a channel region and the source region of the nMOSFET and at a junction between the channel region and the drain region of the nMOSFET is changed by very thin high-concentration segregation layers formed by making As atoms, Sb atoms, S atoms or the like segregate at the time of forming the NiGe layer. As a result, Schottky barrier height suitable for the nMOSFET and the pMODFET can be obtained, this being capable of realizing high-speed CMOSFETS.
US08187955B2	Graphene growth on a carbon-containing semiconductor layer A semiconductor-carbon alloy layer is formed on the surface of a semiconductor substrate, which may be a commercially available semiconductor substrate such as a silicon substrate. The semiconductor-carbon alloy layer is converted into at least one graphene layer during a high temperature anneal, during which the semiconductor material on the surface of the semiconductor-carbon alloy layer is evaporated selective to the carbon atoms. As the semiconductor atoms are selectively removed and the carbon concentration on the surface of the semiconductor-carbon alloy layer increases, the remaining carbon atoms in the top layers of the semiconductor-carbon alloy layer coalesce to form a graphene layer having at least one graphene monolayer. Thus, a graphene layer may be provided on a commercially available semiconductor substrate having a diameter of 200 mm or 300 mm.
US08187954B2	Method for manufacturing silicon single crystal wafer The present invention provides a method for manufacturing a silicon single crystal wafer, in which a silicon single crystal wafer that is fabricated based on a Czochralski method and has an entire plane in a radial direction formed of an N region is subjected to a rapid thermal annealing in an oxidizing atmosphere, an oxide film formed in the rapid thermal annealing in the oxidizing atmosphere is removed, and then a rapid thermal annealing is carried out in a nitriding atmosphere, an Ar atmosphere, or a mixed atmosphere of these atmospheres. As a result, there can be provided the manufacturing method that can inexpensively manufacture a silicon single crystal wafer both in which a DZ layer is formed in a wafer surface layer to provide excellent device characteristics and in which an oxide precipitate functioning as a gettering site can be sufficiently formed in a bulk region.
US08187949B2	Semiconductor device and method of manufacturing the same When a thin semiconductor device is formed by grinding a wafer, it has been necessary to dice the wafer into dies and process the back surfaces of the dies separately. In the invention, a wafer 2a is half-diced from the front surface thereof to form groove portions 4 therein, and in this state, the front surface of the wafer 2a is attached to a supporting body 5 having rigidity with an adhesive layer 6. Then, the wafer 2a is ground from the back surface and diced into individual dies 2b, and then a back surface process including a heat treatment such as the formation of back surface electrodes 9a is performed in the state where the dies 2b are attached to the supporting body 5.
US08187947B2	Capacitor structure in trench structures of semiconductor devices and semiconductor devices comprising capacitor structures of this type and methods for fabricating the same A capacitor structure in trench structures of a semiconductor device includes conductive regions made of metallic and/or semiconducting materials. The conducting regions are surrounded by a dielectric and form stacked layers in the trench structure of the semiconductor device.
US08187944B2	Patterned capacitor ground shield for inductor in an integrated circuit Integrated circuits are disclosed including at least one inductor-capacitor component, where each of the inductor-capacitor components includes an inductor and a capacitor constructed between the inductor and a substrate. The inductor includes at least one metal loop over a shield pattern forming a first capacitor terminal over patterned oxide layer with a second capacitor layer between the patterned oxide layer and the substrate.
US08187934B2	Reverse construction memory cell A method of fabricating a memory cell comprises forming a plurality of doped semiconductor layers on a carrier substrate. The method further comprises forming a plurality of digit lines separated by an insulating material. The digit lines are arrayed over the doped semiconductor layers. The method further comprises etching a plurality of trenches into the doped semiconductor layers. The method further comprises depositing an insulating material into the plurality of trenches to form a plurality of electrically isolated transistor pillars. The method further comprises bonding at least a portion of the structure formed on the carrier substrate to a host substrate. The method further comprises separating the carrier substrate from the host substrate.
US08187933B2	Methods of forming dielectric material-containing structures Some embodiments include dielectric structures. The structures include first and second portions that are directly against one another. The first portion may contain a homogeneous mixture of a first phase and a second phase. The first phase may have a dielectric constant of greater than or equal to 25, and the second phase may have a dielectric constant of less than or equal to 20. The second portion may be entirely a single composition having a dielectric constant of greater than or equal to 25. Some embodiments include electrical components, such as capacitors and transistors, containing dielectric structures of the type described above. Some embodiments include methods of forming dielectric structures, and some embodiments include methods of forming electrical components.
US08187932B2	Three dimensional horizontal diode non-volatile memory array and method of making thereof A non-volatile memory device contains a three dimensional stack of horizontal diodes located in a trench in an insulating material, a plurality of storage elements, a plurality of word lines extending substantially vertically, and a plurality of bit lines. Each of the plurality of bit lines has a first portion that extends up along at least one side of the trench and a second portion that extends substantially horizontally through the three dimensional stack of the horizontal diodes. Each of the horizontal diodes is a steering element of a respective non-volatile memory cell of the non-volatile memory device, and each of the plurality of storage elements is located adjacent to a respective steering element.
US08187931B2	Method for fabricating a semiconductor device with a substrate protrusion A semiconductor device includes a substrate having an active region and an isolation region, a gate pattern crossing both the active region and the isolation region of the substrate, and a protrusion having a surface higher than that of the substrate over at least an edge of the active region contacting a portion of the isolation region under the gate pattern.
US08187924B2	Method, design program and design support device for semiconductor integrated circuit, and semiconductor integrated circuit A design method for a semiconductor integrated circuit, includes: a first calculating step; a second calculating step; and a setting step. The first step is a step of calculating a consumption current amount of a layout target circuit based on circuit information. The second calculating step is a step of calculating a suppliable current amount per unit area in a region where a power can be supplied from a power wiring line. The setting step is a step of setting a cell size of the layout target circuit based on the consumption current amount so that a consumption current amount per unit area of the layout target circuit is smaller than the suppliable current amount per unit area.
US08187922B2	Low cost flexible substrate A low cost flexible substrate is described which comprises a thin metal foil and a layer of solder mask. The metal foil layer is patterned to create tracks and lands for solder bonding and/or wirebonding and the layer of solder mask is patterned to create openings for solder bonding, wirebonding and/or for mounting the die. The substrate may be used as a package substrate to create a packaged die or may be used as a replacement for more expensive flexible printed circuit boards.
US08187918B2	Methods of forming multi-level cell of semiconductor memory Provided is a method of forming a semiconductor memory cell in which in order to store two bits or more data in a memory cell, three or more bottom electrode contacts (BECs) and phase-change materials (GST) have a parallel structure on a single contact plug (CP) and set resistances are changed depending on thicknesses (S), lengths (L) or resistivities (ρ) of the three or more bottom electrode contacts, so that a reset resistance and three different set resistances enable data other than in set and reset states to be stored. Also, a method of forming a memory cell in which three or more phase-change materials (GST) have a parallel structure on a single bottom electrode contact, and the phase-change materials have different set resistances depending on composition ratio or type, so that four or more different resistances can be implemented is provided.
US08187915B2	Aryl dicarboxylic acid diimidazole-based compounds as n-type semiconductor materials for thin film transistors A process for fabricating a thin film semiconductor device includes the following steps, but not necessarily in the noted order. Firstly, a thin film of organic semiconductor material is deposited onto a substrate. This thin film of organic semiconductor material comprises organic semiconductor material that comprises one or more aryl dicarboxylic diimidazole-based compounds of claim 1 such that the film exhibits a field effect electron mobility that is greater than 0.005 cm2/Vs. Then, the process includes forming a spaced apart source electrode and drain electrode, wherein the source electrode and the drain electrode are separated by and electrically connected with, the n-channel semiconductor film. A gate electrode is then formed, spaced apart from the semiconductor material. One or more of the thin film semiconductor devices (or transistors) can be incorporated into an electronic device.
US08187914B2	Methods of forming a phase change memory device Provided are methods of forming a phase change memory device. A semiconductor device having a lower electrode and an interlayer insulating layer may be prepared. The lower electrode may be surrounded by the interlayer insulating layer. Source gases, a reaction gas and a purge gas may be injected into a process chamber of a semiconductor fabrication device to form a phase change material layer on a semiconductor substrate. The source gases may be simultaneously injected into the process chamber. The phase change material layer may be in contact with the lower electrode through the interlayer insulating layer. The phase change material layer may be etched to form a phase change memory cell in the interlayer insulating layer. An upper electrode may be formed on the phase change memory cell.
US08187911B2	Method for forming the separating lines of a photovoltaic module with series-connected cells For forming the separating lines, (5, 6, 7) which are produced in the functional layers (2, 3, 4) deposited on a transparent substrate (1) during manufacture of a photo-voltaic module with series-connected cells (C1, C2, . . . ), at least one laser scanner (8) is used whose laser beam (14) produces in the field (17) scanned thereby a plurality of separating line sections (18, 18′) disposed side by side in the functional layer (2, 3, 4). The laser scanner (8) is moved relative to the coated substrate (1) in the direction (Y) of the separating lines (5, 6, 7), thereby giving rise to an overlap (36) of adjacent fields (17, 17′). At the same time, the laser scanner (8) produces separating line sections (18, 18′) which are of hook-shaped configuration at least at one end (32) so as to form a catching area in which the ends (31, 32) of the separating line sections (18, 18′) of adjacent fields (17, 17′) overlap.
US08187909B2	Backside illuminated image sensor having deep light reflective trenches An array of pixels is formed using a semiconductor layer having a frontside and a backside through which incident light is received. Each pixel typically includes a photosensitive region formed in the semiconductor layer and a trench formed adjacent to the photosensitive region. The trench causes the incident light to be directed away from the trench and towards the photosensitive region.
US08187903B2	Method of epitaxially growing piezoresistors A method of forming a device with a piezoresistor is disclosed herein. In one embodiment, the method includes providing a substrate, etching a trench in the substrate to form a vertical wall, growing a piezoresistor layer epitaxially on the vertical wall, and separating the vertical wall from an underlying layer of the substrate that extends along a horizontal plane such that the piezoresistor layer is movable with respect to the underlying layer within the horizontal plane.
US08187901B2	Epitaxial formation support structures and associated methods Epitaxial formation support structures and associated methods of manufacturing epitaxial formation support structures and solid state lighting devices are disclosed herein. In several embodiments, a method of manufacturing an epitaxial formation support substrate can include forming an uncured support substrate that has a first side, a second side opposite the first side, and coefficient of thermal expansion substantially similar to N-type gallium nitride. The method can further include positioning the first side of the uncured support substrate on a first surface of a first reference plate and positioning a second surface of a second reference plate on the second side to form a stack. The first and second surfaces can include uniformly flat portions. The method can also include firing the stack to sinter the uncured support substrate. At least side of the support substrate can form a planar surface that is substantially uniformly flat.
US08187900B2	Optimization of polishing stop design The present invention provides a method of fabricating vertical LED structures in which the substrate used for epitaxial layer growth is removed through polishing. The polishing technique used in an exemplary embodiment is chemical mechanical polishing using polish stops to provide a sufficiently level plane. Polish stops are provided in the multilayer structure before polishing the surface, the hardness of the polish stop material being greater than the hardness of the material that needs to be removed. Consequently, vertical LEDs can be produced at a lower cost and higher yield compared to either laser lift-off or conventional polishing. Exemplary vertical LEDs are GaN LEDs. The polish stops may be removed by saw dicing, laser dicing or plasma etching.
US08187896B1	Online gaming system for simulating a baseball game An online gaming system for simulating a baseball game comprising: a server with a processor, a network in communication with the server, at least one client device in communication with the network, wherein the at least one client device has an input device, a display device, and a monetary acceptance feature, and a database in communication with the processor. The database comprises electronic decks of baseball offense, defense, and playing cards, and computer instructions for randomizing the decks, permitting input of a bet from the input device and monetary acceptance feature, dealing cards, permitting selection and display of cards, determining a game outcome based on the cards selected, and awarding winnings based on the bet and the game outcome.
US08187890B2	Rapid sensing of toxic metals with hybrid inorganic materials Methods for rapid sensing of dissolved toxic heavy metals use a hybrid inorganic material (“HIM”), which is synthesized from hydrated iron oxide (“HFO”) and calcium magnesium silicate. HIM thus synthesized is used in sensing dissolved toxic heavy metals. Water containing toxic heavy metals (e.g., lead, copper, zinc, nickel, etc.) is passed through a sorbent bed of HIM, whereupon it shows a sharp drop in pH after a certain length of time. The presence of HFO and calcium magnesium silicates in HIM synergistically provide a precipitous drop in pH, which is characteristic of the concentration and type of toxic heavy metal. Therefore, observing a change in pH indicates the presence and identity of heavy metal ions in a test water sample.
US08187887B2	Method and apparatus for determining radiation The present invention relates to devices, systems, and methods for determination of ionizing radiation. In some embodiments, the devices comprise nanocomposite materials containing nanostructures (e.g., carbon nanotubes) dispersed in radiation sensitive polymers. In some cases, the device may include a conductive pathway that may be affected upon exposure to ionizing radiation. Embodiments described herein may provide inexpensive, large area, low power, and highly sensitive radiation detection materials/devices.
US08187884B2	Method of enhancing homologous recombination of somatic cells and method of constructing specific antibody The present invention provides a novel method for obtaining diverse antibodies as a result of markedly enhancing the somatic homologous recombination at an antibody locus in immunocytes.By putting immunocytes in which DNA homologous recombination is occurring at an antibody locus (for example, DT40 cells and the like) into contact and the like with histone acetylase inhibitor and the like (for example, trichostatin A and the like), thereby relaxing the chromatin structure at said antibody locus, somatic homologous recombination at an antibody locus is enhanced, and the production of diverse antibody molecules is made possible.The production of antibodies that bind specifically to antigens from cell populations in which the antibody molecules have been diversified by the enhancement of somatic homologous recombination is made possible by using an appropriate selection method (for example, beads coated with antigen and the like).
US08187880B2	Composite materials comprising supported porous gels containing metal-affinity ligands This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
US08187878B2	Methods for increasing definitive endoderm differentiation of pluripotent human embryonic stem cells with PI-3 kinase inhibitors The present invention provides compositions and methods for the production of differentiated mammalian cells. More particularly, the present invention provides cellular differentiation methods employing culturing the cells on a feeder layer or under feeder-free conditions in cell culture and further contacting the cells with an inhibitor of the PI3-kinase pathway and a member of the TGFb family for the generation of differentiated mammalian cells from pluripotent mammalian stem cells. Preferably, the differentiated cell is selected from the group consisting of a mesendodermal cell, a mesodermal cell, and an endodermal cell.
US08187873B2	Monoclonal antibody to soluble LOX-1 It is intended to provide a monoclonal antibody that specifically recognizes human soluble LOX-1, particularly a monoclonal antibody with a dissociation constant (Kd) for human soluble LOX-1 of 1×10−9 (M) or less. The antibody can be produced from a hybridoma prepared by a method including the following steps of: (1) immunizing a non-human animal with a prokaryotic cell-derived human LOX-1 extracellular domain; (2) collecting antibody-producing cells from the animal; (3) fusing the antibody-producing cells with myeloma cells; (4) selecting hybridomas that produce a monoclonal antibody reacting with the human LOX-1 extracellular domain from the fused cells obtained in the above step; and (5) selecting a hybridoma that produces a monoclonal antibody reacting with a eukaryotic cell-derived human LOX-1 extracellular domain from the selected hybridomas.
US08187871B2	Co-crystallization of ERR-α with a ligand that forms a reversible covalent bond The crystal structure of the ligand binding domain of ERR-α in complex with a ligand that forms a reversible thioether bond to Cys325 of ERR-α, methods to measure dissociation rates for ligands that form reversible covalent bonds, and methods to design ligands that form reversible covalent bonds for use as modulators of ERR-α activity are disclosed. The crystal structure and methods provide a novel molecular mechanism for modulation of the activity of ERR-α and provide the basis for rational drug design to obtain potent specific ligands for use as modulators of the activity of this new drug target.
US08187870B2	Means for obtaining avirulent leishmania promastigotes, promastigotes obtained, and the applications thereof The invention relates to an expression vector of a gene coding for an antigenic protein of Leishmania promastigote, characterized in that it comprises a PSA gene insert in opposite orientation. The invention can be applied to the development of mutants under-expressing, or no longer expressing, genes coding for an antigenic protein of Leishmania promastigote, and to the therapeutic and/or vaccine-oriented uses thereof.
US08187868B2	Device for trapping extraneous gas A device for trapping extraneous gas or bubbles is disclosed. The device is defined as having a gas collection area in a tapered neck portion such that when used as a cell culturing apparatus, extraneous gas or bubbles are trapped and isolated from the cell growth areas where cells or media reside.
US08187867B2	Probe connector assembly and method of use A probe assembly includes a tubular sleeve having a passage extending between a first end and an opposing second end. The tubular sleeve is movable between an extended position wherein the first end and the opposing second end are spaced apart and a collapsed position wherein the first end and the opposing second end are moved closer together. A connector is secured to the second end of the tubular sleeve, the connector having an opening extending therethrough that communicates with the passage of the tubular sleeve, a sealing layer removably covering the opening of the connector. An elongated probe has a first end and an opposing second end, the second end of the probe being positioned within the passage of the tubular sleeve, the second end of the probe being configured to pass through the opening of the connector when the sealing layer is removed therefrom.
US08187865B2	Nanowire sensor, sensor array, and method for making the same The present invention relates to a nanowire sensor and method for forming the same. More specifically, the nanowire sensor comprises at least one nanowire formed on a substrate, with a sensor receptor disposed on a surface of the nanowire, thereby forming a receptor-coated nanowire. The nanowire sensor can be arranged as a sensor sub-unit comprising a plurality of homogeneously receptor-coated nanowires. A plurality of sensor subunits can be formed to collectively comprise a nanowire sensor array. Each sensor subunit in the nanowire sensor array can be formed to sense a different stimulus, allowing a user to sense a plurality of stimuli. Additionally, each sensor subunit can be formed to sense the same stimuli through different aspects of the stimulus. The sensor array is fabricated through a variety of techniques, such as by creating nanopores on a substrate and electrodepositing nanowires within the nanopores.
US08187861B1	Phosphate removal-recovery and biofuel feedstock system For extracting phosphorous from algae-in a body of water, the algae are deposited into a sealable tank (200) that is then evacuated, thereby rupturing the algal cell walls. The ruptured algae are then moved to a second tank (260), mixed with water and bacterial cultures, and allowed to settle until the lipids rise to the top and the oil-less debris settles to the bottom. The second tank also contains sacrificial (295) and rusted electrodes (320). The phosphorous from the algae combines with the rust. The lipids and debris are then removed. Next, an electrical source (315) causes the rust to be removed from the rusted electrodes and settle. In addition, a phosphorous-rich scum floats to the top. These components are placed in storage containers for later use and the water is returned, thereby reducing its phosphorous content.
US08187851B2	Method of forming a molded protein matrix for a sensor A method for formulating and immobilizing a protein and a protein matrix formed by the method. The protein matrix preparation method results in a physically and chemically stable protein matrix that has low swelling, non-leaching, high activity, and high mechanical strength properties. The method includes cross-linking and hardening the protein mixture and using a mold to form a protein into a desired shape and size.
US08187849B2	Non-sterile fermentation of bioethanol A range of concentrations exists in which fermentation inhibitors derived from pretreatment of lignocellulosic feed stocks inhibit growth of lactic acid bacteria without affecting fermentive yeast. By optimizing levels of fermentation inhibitors to fall within this range, yeast fermentations of lignocellulosic biomass can be conducted under non-sterile conditions with ethanol yields comparable to those achieved under sterile conditions. Optimised inhibitor levels can be achieved by controlling the water/biomass ratio of a lignocellulosic biomass during and after pretreatment, for example by washing the fiber fraction of a previously pretreated lignocellulosic biomass with a pre-defined amount of fresh water or recycled process solutions. Crude extracts of liquid fraction or process solutions from pretreatment of lignocellulosic biomass can also provide an effective anti-bacterial treatment for first generation starch fermentations.
US08187848B2	Methods of processing ensiled biomass The invention relates to methods of processing ensiled biomass for production of bioethanol or other fermentation products and, in particular, to methods that do not require expensive pretreatment (e.g. heat or chemical pretreatment).
US08187847B2	Process for producing erythritol using Moniliella tomentosa strains in the presence of neutral inorganic nitrates, such as potassium nitrate, ammonium nitrate or sodium nitrate, as nitrogen source The present invention relates to the use of at least one inorganic nitrate in a fermentation process for producing erythritol using a yeast strain of the Moniliella species as an erythritol-producing microorganism characterized in that the at least one inorganic nitrate is simultaneously used as a main nitrogen source and as a pH regulator in the culture medium, as well as to such an improved method for producing erythritol.
US08187846B2	Enhanced production of lipids containing polyenoic fatty acid by very high density cultures of eukaryotic microbes in fermentors The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
US08187844B2	Anti-fungal composition Natamycin is separated and recovered from a fermentation broth containing biomass and natamycin by adjusting the pH of a natamycin-containing suspension first to dissolve the natamycin in a solvent then adjusting the pH again to precipitate the dissolved natamycin which is used as an antifungal used to protect products susceptible to fungal spoilage.
US08187843B2	Method for production of L-glutamine According to the present invention, it is possible to provide a microorganism belonging to the genus Corynebacterium, wherein the activity of (1) a protein having the amino acid sequence shown by any one of SEQ ID NO:1 to 3, or (2) a protein having a homology of 80% or more to the amino acid sequence shown by any one of SEQ ID NO:1 to 3, and having substantially the same activity as the activity of a protein having the amino acid sequence shown by any one of SEQ ID NO:1 to 3, has been reduced or lost, and wherein the activity of (3) a protein having the amino acid sequence shown by SEQ ID NO:4, or (4) a protein having a homology of 80% or more to the amino acid sequence shown by SEQ ID NO:4, and having substantially the same activity as the activity of a protein having the amino acid sequence shown by SEQ ID NO:4, has been reduced or lost, and a process for producing L-glutamine using the microorganism and the like.
US08187839B2	Anti-notch3 agonist antibodies and their use in the treatment of notch3-related diseases The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
US08187832B2	Method of detecting an amount of a cholinesterase inhibitor in a sample A method of detecting an amount of a cholinesterase inhibitor in a sample comprising steps of: (a) contacting the sample with an agent capable of recovering the cholinesterase inhibitor from the sample so that the cholinesterase inhibitor is recovered, wherein the agent comprises a reactivity towards phosphyl moieties; (b) isolating the recovered cholinesterase inhibitor from the sample; (c) contacting the isolated cholinesterase inhibitor from step (b) with a test cholinesterase wherein the cholinesterase activity of the test cholinesterase before step (a) is known; and (d) measuring the cholinesterase activity to determine the amount of cholinesterase inhibitor in the sample based on the inhibition of the test cholinesterase activity from the known activity of the test cholinesterase before step (a).
US08187828B2	Use of PAK inhibitor for the treatment of a joint disease The invention refers to the use of a p21-activated kinase (PAK) inhibitor as a target protein for the discovery of a PAK inhibitor as a medicament for the treatment of a joint disease.
US08187827B2	Diagnostic methods for acute ischemic disease using activated hepcidin as an indicator An objective of the present invention is to provide methods of testing for acute ischemic diseases using active hepcidin as an indicator, methods for determining the timing to administer an agent for treating the disease, and kits for these methods. To accomplish the objective, the present inventors analyzed the serum proteome patterns characteristic of acute myocardial infarction patients using SELDI-TOF-MS. As a result, it was found that hepcidin-20 has a very high correlation with acute myocardial infarction. Furthermore, the present inventors discovered that at the time of disease onset, the blood concentration of hepcidin-20 rises sharply in particular, and shows high levels within six hours, especially four hours of onset. The present invention enables early diagnosis of acute ischemic diseases.
US08187826B2	Quantitative analysis of in vivo mutation at the Pig-A locus The invention relates to methods and kits for the quantitative analysis of in vivo mutation frequencies of the Pig-A gene in individuals exposed to a genotoxicant, particularly using peripheral blood samples of vertebrates.
US08187824B2	Porphyrinic compounds for use in flow cytometry The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The method comprises utilizing as the detectable luminescent compound a compound comprising a porphyrinic macrocycle such as a porphyrin, chlorin, bacteriochlorin, or isobacteriochlorin. In particular embodiments, the detectable luminescent compound comprises a compound of the formula A-A′-Z—B′—B, wherein: A is a targeting group or member of a specific binding pair that specifically binds the detectable luminescent compound to the target compound, cell or particle; A′ is a linker group or covalent bond; B′ is a linker group or covalent bond; B is a water-soluble group; and Z is the porphyrinic macrocycle.
US08187816B2	Probe set, probe-immoblized carrier, and genetic testing method for detecting Anaerococcus prevotii A nucleic acid probe for classification of pathogenic bacterial species is capable of collectively detecting bacterial strains of the same species and differentially detecting them from other bacterial species. Any one of the base sequences of SEQ ID NOS. 65 to 67 or a combination of at least two of them is used for detecting the gene of an infectious disease pathogenic bacterium.
US08187815B2	Method to quantify siRNAs, miRNAs and polymorphic miRNAs The present teachings provide methods, compositions, and kits for quantifying target polynucleotides. In some embodiments, a reverse stem-loop ligation probe is ligated to the 3′ end of a target polynucleotide, using a ligase that can ligate the 3′ end of RNA to the 5′ end of DNA using a DNA template, such as T4 DNA ligase. Following digestion to form an elongated target polynucleotide with a liberated end, a reverse transcription reaction can be performed, followed by a PCR. In some embodiments, the methods of the present teachings can discriminate between polymorphic polynucleotides that vary by as little as one nucleotide.
US08187812B2	DNA recombination junction detection The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
US08187811B2	Polymorphisms associated with Parkinson's disease The invention provides human polymorphisms that are associated with Parkinson's disease (PD). Also disclosed are compositions and methods for use in diagnostics, prognostics, prevention, treatment and/or study of PD.
US08187810B2	Method for diagnosing overactive bladder Techniques for diagnosing overactive bladder (OAB) in a patient are provided. For example, a technique for diagnosing overactive bladder in a patient includes the step of obtaining peripheral blood mononuclear cells (PBMC) from the patient to provide a reporter function in the patient.
US08187808B2	Barriers for facilitating biological reactions The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or hydrophobic barriers in sample separation, purification, modification, and analysis processes.
US08187806B2	Association of GSTM1 with autism and assays and methods based thereon The present invention provides novel markers and assays for autism based on the association of GSTM1 with autism. The invention relates to the use and application of as a susceptibility marker for autism. GSTM1 may be combined with other markers in methods and assays for diagnosis, prenatal diagnosis, and assessment of autism. The invention further relates to a likelihood ratio test. In addition, the present invention discloses a novel method for identifying individuals who are genetically susceptible to have offspring with autism wherein the genotype of GSTM1, alone or in combination with other genetic markers, is determined.
US08187805B2	Method of detecting nucleic acid and utilization thereof It is intended to provide a method of detecting a nucleic acid whereby a target nucleic acid can be accurately and quickly detected at an elevated detection sensitivity compared with the existing methods; and a gene detection kit with the use of this method. A sample containing cells is fixed to a support and nucleic acids are amplified on the support as such. Then, a nucleic acid thus amplified is detected. Since the nucleic acids are not detected from the sample in this method, a lowering in the detection sensitivity due to the nucleic acid loss in the step of extracting the nucleic acids can be prevented. Since the amplified nucleic acid is detected, furthermore, detection can be made even though the nucleic acid is contained only in a trace amount in the sample.
US08187804B2	Specific marker Lmx1a on dopaminergic neurons The present invention identified Lmx1a genes, which are expressed in dopaminergic neurons at all differentiation stages, from proliferating dopaminergic neuron progenitor cells before cell cycle exit to cells after cell cycle exit. Lmx1a expression in cells can be used as an indicator when selecting cells suitable for transplantation therapy for neurodegenerative diseases such as Parkinson's disease, and is useful as a marker for screening agents involved in the induction of dopaminergic neuron differentiation.
US08187799B2	Stabilization of liquid solutions of recombinant protein for frozen storage The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of −56° C. or higher.
US08187795B2	Patterning methods for stretchable structures Described herein are processing techniques for fabrication of stretchable and/or flexible electronic devices using laser ablation patterning methods. The laser ablation patterning methods utilized herein allow for efficient manufacture of large area (e.g., up to 1 mm2 or greater or 1 m2 or greater) stretchable and/or flexible electronic devices, for example manufacturing methods permitting a reduced number of steps. The techniques described herein further provide for improved heterogeneous integration of components within an electronic device, for example components having improved alignment and/or relative positioning within an electronic device. Also described herein are flexible and/or stretchable electronic devices, such as interconnects, sensors and actuators.
US08187793B2	Ablatable elements for making flexographic printing plates Flexographic printing plates and other relief images can be formed from a laser-ablatable element having a laser-ablatable layer that is at least 20 μm in thickness. The laser-ablatable layer includes a film-forming material that is a laser-laser-ablatable material or the film-forming material has dispersed therein a laser-ablatable material. The laser-ablatable material is a polymeric material that when heated to 300° C. at a rate of 10° C./minute, loses at least 60% of its mass to form at least one predominant low molecular weight product. The element can be imaged by ablation at an energy of at least 1 J/cm2 to provide a relief image.
US08187791B2	Lithographic printing plate precursor and plate making method thereof A lithographic printing plate precursor includes: a support; and an image-recording layer containing (A) an infrared absorbing agent, (B) a radical polymerization initiator, (C) a polymerizable compound and (D) an epoxy compound having a molecular weight of 1,000 or less.
US08187789B2	Positive resist composition and method of forming resist pattern A positive resist composition, including a resin component (A) which exhibits increased solubility in an alkali developing solution under action of an acid, and an acid generator component (B) which generates an acid upon exposure, wherein the component (A) includes a structural unit (a1) derived from a hydroxystyrene, and a structural unit (a2) containing an acid dissociable, dissolution inhibiting group; and the component (B) includes an acid generator (B1) composed of a compound represented by the general formula (b1) shown below: [Chemical Formula 1] X-Q1-Y1—SO3−A+ (b1) (in the formula, Q1 represents a bivalent linking group containing an oxygen atom; Y1 represents an alkylene group of 1 to 4 carbon atoms which may contain a substituent or a fluorinated alkylene group of 1 to 4 carbon atoms which may contain a substituent; X represents a hydrocarbon group of 3 to 30 carbon atoms which may contain a substituent; and A+ represents an organic cation).
US08187788B2	Photosensitive resin composition and photosensitive film Disclosed is a photosensitive resin composition comprising an alkali-soluble resin, wherein the dissolution rate of the alkali-soluble resin in an aqueous sodium carbonate solution is not less than 0.04 μm/sec. When a photosensitive layer having a thickness of 30 μm is formed by applying the photosensitive resin composition onto a base and removing the solvent by heating, and thus-obtained photosensitive layer is irradiated with an active ray of 1000 mJ/cm2 or less, the dissolution rate of the portion irradiated with the active ray in the photosensitive layer made of the photosensitive resin composition is not less than 0.22 μm/sec and the film residual rate of the portion not irradiated with the active ray is not less than 90%.
US08187783B2	Method of manufacturing toner, toner, two-component developer, developing device and image forming apparatus A method of manufacturing a toner in which uneven distribution of toner ingredients by subjecting them to fine dispersion is prevented and which is excellent in transferability, cleaning properties, anti-filming properties, anti-blocking properties, high-temperature offset resisting properties and transparency is provided. Melt-kneaded substances include binder resins, colorants and release agents, respectively. The colorant and the release agent are dispersed in the binder resin. The melt-kneaded substance is negatively charged by an anionic dispersant, whereas the melt-kneaded substance is positively charged by a cationic dispersant. An aggregate is formed by heteroaggregation of the melt-kneaded substances. The aggregate is fused by heating and formed into a spherical toner.
US08187780B2	Toner compositions and processes Environmentally friendly toner particles are provided which may, in embodiments, include a biodegradable semi-crystalline polyester resin and a biodegradable amorphous polyester resin.
US08187777B2	Method for manufacturing patterned layer on substrate A method for manufacturing a patterned layer on a substrate with a print head unit includes mounting a print head unit to an ink-jet device, the print head unit including at least two side print heads and one central print head, the print heads each comprising a nozzle line, rotationally moving at least one of the side print heads relative to the central pint head to achieve parallelism, rotating the print head unit around a rotating axis perpendicular to the substrate, linearly moving the side print heads along the respective nozzle line thereof to correspond to pitches of the nozzles and that of the cells on the substrate, depositing ink into the cells on the substrate, and solidifying the ink so as to form a patterned layer on the substrate.
US08187763B2	Cooling liquid composition for fuel cell A coolant composition for a fuel cell unit, which contains at least one aliphatic alcohol having unsaturated bonds in the molecules having 2 to 20 carbon atoms each. The coolant composition maintains the electrical conductivity of the coolant at 10 μS/cm or below as well as the fluctuation of the electrical conductivity within the range of 0 to 10 μS/cm.
US08187762B2	Fuel cell cooling device with ion extraction medium A fuel cell cooling device has a cooling loop for circulating a coolant fluid. At least during the operation of the fuel cell, an ion extraction medium that is in the liquid state is provided. A method for cleaning a coolant with a corresponding fuel cell cooling device is provided as well.
US08187761B2	Power supply apparatus and method for line connection type fuel cell system A power supply apparatus for a line connection type fuel cell system includes a power converter system (PCS) control power supply which generates PCS control power from line power, a balance of plant (BOP) power supply which generates BOP power from line power, a regulator which generates PCS control power from the BOP power, a first switching unit switched by a control signal, which directs the line power to one of the PCS control power supply and the BOP power supply, a second switching unit switched by a control signal, which selects an output of one of the PCS control power supply and the regulator to provide PCS control power, and a controller which controls switching of the first and second switching units in response to a starting command.
US08187756B2	Fuel cell system An ion exchange resin member 20 that serves as an impurity remover for removing impurities from fluid F discharged from a fuel cell 100 is placed in a discharge passage for the fluid F to flow through, and a dispersion means for dispersing the fluid F over, and making the fluid F flow to, an entry-side surface 21 of the ion exchange resin member 20 is placed upstream from the ion exchange resin member 20. Also, a gas discharge part and a liquid discharge part are placed downstream from a fluid outlet of the ion exchange resin member 20, and a liquid-movement-preventing means for preventing a liquid in the fluid discharged from the fluid outlet from moving toward the gas discharge part is placed between the ion exchange resin member 20 and at least either the gas discharge part or the liquid discharge part.
US08187750B2	Negative active material including lithium vanadium oxide for non-aqueous rechargeable battery, and non-aqueous rechargeable battery including same The negative active material for a non-aqueous rechargeable battery includes a main component of lithium vanadium oxide, and at least one selected from the group consisting of Li3VO4, vanadium carbide, and mixtures thereof. The Li3VO4 is included in an amount of 0.5 to 3.0 wt % based on the total weight of the negative active material, and the vanadium carbide is included in amount of 0.5 wt % or less based on the total weight of the negative active material. The negative active material can improve discharge capacity of the non-aqueous rechargeable battery.
US08187746B2	Surface modification agents for lithium batteries An active material for an electrochemical device may have a surface modification agent that is a silane, organometallic compound, or a mixture of two or more of such compounds. Both negative and positive electrodes may be prepared from the surface modified active materials. The surface of an electrode may be modified by adding the surface modification agent to a non-aqueous electrolyte used in constructing a battery. An electrode or active material may be modified with a surface modification agent in either the gas phase or in solution. Slurries of the active agent may be prepared and the surface modification agent added, the slurry then be used to cast an electrode that is then dried.
US08187736B2	Cooling system for hybrid vehicles A cooling system for hybrid vehicles is provided with a battery case with a battery storage room for receiving a battery, a motor control unit for controlling an electric motor and a DC-DC converter for converting a voltage of the battery. The cooling system includes a blower for drawing an air existing in a passenger compartment of a vehicle, an introduction duct through which the air is introduced into the battery storage room to cool the battery, a first supply duct through which the air is supplied from the battery storage room to the DC-DC converter to cool the latter, a second supply duct through which the air is supplied from the battery storage room to the motor control unit to cool the latter, and an air distributor means for distributing the air flowing out of the battery storage room to the first supply duct and the second supply duct.
US08187730B2	Acenaphthoquinoxaline derivative, light-emitting element, light-emitting device, and electronic device An acenaphthoquinoxaline derivative represented by a general formula (G1) is provided. The acenaphthoquinoxaline derivative represented by the general formula (G1) easily receives electrons and has an electron-transporting property. Therefore, the acenaphthoquinoxaline derivative can be suitably used for a light-emitting element.
US08187729B2	Organic electroluminescence device A process for preparing a platinum complex represented by the following formula (1) includes reacting a compound represented by the following formula (B-2) and a compound represented by the following formula (B-2′) with a compound represented by the following formula (A-0) to obtain a compound represented by the following formula (C-0); and reacting the compound represented by the formula (C-0) with a platinum salt:
US08187728B2	Organic electroluminescent device and display device An organic electroluminescent is provided having an anode, a cathode, and at least one organic layer including a light-emitting layer provided between the anode and the cathode, wherein the organic layer includes an amine compound represented by the following formula (1): wherein Ar1 to Ar4 each independently represent a specific aromatic group; R1 and R2 each independently represent a hydrogen atom, a halogen atom or a particular substituent group; and n stands for an integer of 1, 2 or 3.
US08187727B2	Imidazole derivatives, preparation method thereof and organic electronic device using the same The present invention relates to a new imidazole derivative, a method for preparing the derivative, and an organic electronic device using the derivative. The imidazole derivative according to the invention can perform functions of hole injection, hole transportation, electron injection, electron transportation, and/or light emission in an organic electronic device including an organic light-emitting device. The organic electronic device according to the invention exhibits excellent characteristics in terms of efficiency, drive voltage and stability.
US08187726B2	Nanoparticle-resin composite material, light emitting device assembly, and filling material for the light-emitting device assembly A nanoparticle-resin composite material is provided. The material has a transparent characteristic and a refractive index of at least 1.55 in the visible light region. The composite material includes inorganic nanoparticles dispersed in a polymer having a siloxane bond, the inorganic nanoparticles being coated with an organic compound. The organic compound is at least one compound selected from the group consisting of carboxylic acids, phosphinic acid, phosphonic acid, sulfinic acid, sulfonic acid, and thiols, and the selected compound contains an aryl group or an aryloxy group. The polymer is selected from the group consisting of methylphenyl polysiloxane, methylphenyl hydrogen polysiloxane, a mixture methylphenyl polysiloxane and methylphenyl hydrogen polysiloxane, or methylphenyl polysiloxane, methylphenyl hydrogen polysiloxane, and a mixture of methylphenyl polysiloxane and methylphenyl hydrogen polysiloxane. Parts of the side chains and/or terminals of the methylphenyl polysiloxane and the methylphenyl hydrogen polysiloxane are substituted by epoxy groups, carboxyl groups, carbinol groups, methacryl groups, polyether groups, or vinyl groups.
US08187724B2	Method of manufacture of a dual alloy impeller There is provided a method for fabricating a dual alloy structure that may in turn be machined to fabricate a rotary component for use in a gas turbine engine. The method provides a powder metal (PM) nickel based superalloy and a nickel aluminide intermetallic based alloy. The powder metal (PM) nickel based superalloy displays characteristics, such as improved strength, low cycle fatigue resistance, fracture toughness, and crack growth resistance. The nickel aluminide intermetallic based alloy displays characteristics, such as high temperature creep and oxidation resistance, suitable for use in the outer radial area of an impeller. A bore sub-element is fabricated from the powder metal (PM) nickel based superalloy. A body sub-element is fabricated from the nickel aluminide intermetallic based alloy. The bore sub-element and body sub-element are joined by inertia welding or diffusion bonding at a common mating surface.
US08187723B2	Surface-treated copper foil, manufacturing method of the surface-treated copper foil, and surface-treated copper foil coated with very thin primer resin layer A surface-treated copper foil comprising an electrodeposited copper foil with a chromium-free rust-proofing layer which exhibits good performance in peel strength and resistance to peel loss after chemical treatment as a printed wiring board. The surface-treated copper foil comprises a rust-proofing layer and a silane coupling agent layer formed on an electrodeposited copper foil , wherein the rust-proofing layer comprises a nickel layer having a thickness by weight of 5 to 40 mg/m2 and a tin layer having a thickness by weight of 5 to 40 mg/m2 stacked in this order, and the silane coupling layer is applied on top of the tin layer. The surface-treated copper foil may be further coated with a very thin primer resin layer having a thickness of 0.5 to 5 μm.
US08187722B2	Copper foil with carrier sheet, method for manufacturing copper foil with carrier sheet, and surface-treated copper foil with carrier sheet An object of the present invention is to provide a copper foil with carrier sheet which permits releasing of the carrier sheet from the copper foil layer even when hot pressing at a temperature exceeding 300° C. is applied in the production of a printed wiring board. In order to achieve the object, a copper foil with physically releasable carrier sheet having a copper foil layer on the surface of the carrier sheet through a bonding interface layer, characterized in that the bonding interface layer is composed of a metal layer and a carbon layer. It is preferable for the bonding interface layer to be composed of a metal layer of 1 nm to 50 nm thick and a carbon layer of 1 nm to 20 nm thick.
US08187720B2	Corrosion resistant neutron absorbing coatings A method of forming a corrosion resistant neutron absorbing coating comprising the steps of spray or deposition or sputtering or welding processing to form a composite material made of a spray or deposition or sputtering or welding material, and a neutron absorbing material. Also a corrosion resistant neutron absorbing coating comprising a composite material made of a spray or deposition or sputtering or welding material, and a neutron absorbing material.
US08187718B2	Barrier laminate, barrier film substrate and device Disclosed is a barrier laminate comprising at least one organic layer and at least one inorganic layer, wherein the organic layer is obtained by curing a polymerizable composition comprising 1 to 50% by weight of a polymerizable compound which has a bisphenol skeleton and having an aliphatic group.
US08187714B2	Transparent substrate provided with an electrode Transparent substrate, especially made of glass, associated with an electrode, especially one suitable for solar cells, characterized in that the electrode comprises a first transparent electrically conducting layer composed of an undoped mineral oxide, said first layer being coated with a second transparent electrically conducting layer composed of the same mineral oxide, said mineral oxide however being doped.
US08187710B2	Insulated ultrafine powder, process for producing same and resin composite material with high dielectric constant using same There are disclosed insulated ultrafine powder comprising electroconductive ultrafine powder which is in the form of sphere, spheroid or acicular each having a minor axis in the range of 1 to 100 nm and an insulating film applied thereto; a process for producing the same which is capable of covering the surfaces of the insulated ultrafine powder with the insulating film having a thickness in the range of 0.3 to 100 nm without causing any clearance or vacancy; and a resin composite material which uses the same. A high dielectric constant of the material is assured by adding a small amount of insulated ultrafine powder wherein an insulating film is applied to the electroconductive ultrafine powder, while maintaining the processability and moldability that are the characteristics inherent in a resin material.
US08187706B2	Adhesive composition An adhesive composition is provided which is capable of providing good adhesion strength to the polyimide surface of a flexible circuit board that is exposed on the metal wiring surface and between the traces even when the polyimide surface is relatively smooth. The adhesive composition contains a thermoplastic resin, a polyfunctional acrylate, and a radical polymerization initiator and further contains a monofunctional urethane acrylate having a urethane residue at its terminal end. The monofunctional urethane acrylate is represented by the formula (1): CH2═CR0—COO—R1—NHCOO—R2 (1) wherein R0 is a hydrogen atom or a methyl group, R1 is a divalent hydrocarbon group, and R2 is an optionally substituted lower alkyl group.
US08187705B2	Manganese vanadium tantalum oxide and pigments having a black metallic effect coated with the same Manganese vanadium tantalum oxide that can be represented by the formula MnxVyTazOw, where 1≦x≦3, 0.001≦y≦3, 0.001≦z≦2, and w=7, and alternately, x=1.25≦x≦2.45, 0.1≦y≦2.39, 0.2≦z≦1.9, and w=7, methods of producing MnxVyTazOw, a pigment coated with MnxVyTazOw and a chalcogenide glass layer, and a method of producing the coated pigment are described. The disclosed manganese vanadium tantalum oxide has superior near-infrared reflective properties. The disclosed methods of producing the manganese vanadium tantalum oxide provide products with superior phase purity, appearance and performance and take health and safety into consideration. The construction of the disclosed coated pigment combines the reflective properties of the substrate with the near-infrared reflective properties of MnxVyTazOw, while the chalcogenide glass layer provides aesthetic appeal. The disclosed method of producing the coated pigment involves physical vapor deposition of MnxVyTazOw and the chalcogenide glass layer.
US08187704B2	Optical film, polarizing plate and image display device An optical film, includes: a transparent support; and at least one low refractive index layer, wherein the at least one low refractive index layer is a layer formed from a coating composition containing: (A) an inorganic fine particle; (B) a fluorine-containing copolymer; and (C) a polyfunctional fluorine-containing acrylate, and the polyfunctional fluorine-containing acrylate (C) is represented by the following structural formula: wherein Rf represents a (p+q)-valent perfluoro saturated hydrocarbon group having a carbon number of 1 to 20, which may have an ether bond; p represents an integer of 2 to 10; q represents an integer of 0 to 8, provided that (p+q) represents an integer of 2 to 10; r represents an integer of 0 to 100; and R represents a hydrogen atom, a methyl group, a fluorine atom or a trifluoromethyl group.
US08187700B2	Continuous, carbon-nanotube-reinforced polymer precursors and carbon fibers The present invention relates to a continuous, carbon fiber with nanoscale features comprising carbon and carbon nanotubes, wherein the nanotubes are substantially aligned along a longitudinal axis of the fiber. Also provided is a polyacrylonitrile (PAN) precursor including about 50% to about 99.9% by weight of a melt-spinnable PAN and about 0.01% to about 10% of carbon nanotubes. Other precursor materials such as polyphenylene sulfide, pitch and solution-spinnable PAN are also provided. The precursor can also include a fugitive polymer which is dissociable from the precursor polymer.
US08187697B2	Cooling product A cooling product (e.g., pad, bandage, headband, wrap, cloth, and so forth) that contains a gel configured to cool the skin of a body part when placed adjacent thereto is provided. The gel is contained within a composite that has two or more fibrous layers structured to provide enhanced distribution of the gel therethrough. More specifically, a first fibrous layer may rapidly distribute the gel in primarily the -z direction (direction of thickness) to a second fibrous layer, which then distributes it primarily in the -x and -y directions. The second fibrous layer may then be placed adjacent to a user's skin to provide the desired cooling. Because the gel is distributed primarily in the -x and -y directions, however, direct contact between the gel and skin is limited, thereby reducing the “sticky” feel normally associate with such gels. The cooling product is also flexible, and may be easily adapted to a body part.
US08187692B2	In-mold label and molded article using the same The invention provides an in-mold label which enables the degree of scumming to be judged during printing and imparts a good appearance to molded articles produced through in-mold molding, and which comprises a base layer (I), a heat-sealable resin layer (II), and a printable layer (III) and has a haze in whole layer of 80-100% and an internal haze of 0-20%. The invention further provides a molded article obtained using the label.
US08187689B2	Optical recording medium having write once metal reflective film A pirated optical recording medium may be determined which is produced by physically transferring a shape of pits and lands formed on a substrate of an optical recording medium. The optical recording medium is provided with excellent weatherability and long-term storage reliability. A reflective film formed of an Ag alloy film of Ag100-x-yXxCuy, where X is at least one element among Ti, W, Ta, V, Mo, Nb and Zr, is formed on a substrate on which main data is recorded with a combination of pits and lands. A mark may be formed so that a reproduction signal level in the recorded mark of auxiliary data write once recorded on the reflective film is increased, and a reproduction signal level is decreased in an optical recording medium prepared by physically transferring the surface shape of the pits and lands of the substrate. A pirated optical recording medium may be determined in this manner.
US08187684B2	Double-donnable glove A polychloroprene article comprises a polymer which is more readily chlorinatable that polychloroprene. A method of making the article comprises forming the article from an aqueous dispersion or solution of polychloroprene, characterized in that one or more polymers which are more readily chlorinatable than polychloroprene are included in said dispersion or solution. Preferably, the article is a polychloroprene glove containing carboxylated nitrile rubber, carboxylated styrene butadiene or polyisoprene.
US08187681B2	Transparent film and optical compensatory film, polarizing plate and liquid-crystal display device employing it A novel transparent film is disclosed. Re (λ) and Rth (λ) of the film defined by the following formulae (I) and (II) satisfy the following formulae (III) and (IV): Re(λ)=(nx−ny)×d, (I) Rth(λ)={(nx+ny)/2−nz}×d, (II) 0≦\|Re(630)\|≦50, (III) Rth(400)×Rth(700)≦0, and 0≦\|Rth(700)−Rth(400)\|≦150, (IV) wherein Re (λ) means an in-plane retardation value at a wavelength λ nm (unit: nm); Rth (λ) means a thickness-direction retardation value at a wavelength λ, nm (unit: nm); nx means a refractive index in the in-plane slow-axis direction; ny means a refractive index in the in-plane fast-axis direction; nz means a refractive index in the film thickness direction; and d means a thickness of the film.
US08187678B2	Ultra-thin microporous/hybrid materials Ultra-thin hybrid and/or microporous materials and methods for their fabrication are provided. In one embodiment, the exemplary hybrid membranes can be formed including successive surface activation and reaction steps on a porous support that is patterned or non-patterned. The surface activation can be performed using remote plasma exposure to locally activate the exterior surfaces of porous support. Organic/inorganic hybrid precursors such as organometallic silane precursors can be condensed on the locally activated exterior surfaces, whereby ALD reactions can then take place between the condensed hybrid precursors and a reactant. Various embodiments can also include an intermittent replacement of ALD precursors during the membrane formation so as to enhance the hybrid molecular network of the membranes.
US08187672B2	Residual solvent extraction method and microparticles produced thereby Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step.
US08187670B2	Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device A method for manufacturing an electro-optical device in which thin film layers are formed by drying droplets containing a thin film layer formation material, and these thin film layers are laminated to form a light emitting element, includes mixing lyophilic microparticles that are lyophilic with respect to droplets that form an upper thin film layer into droplets that form a lower thin film layer, and drying the droplets in which these lyophilic microparticles have been mixed to form the lower thin film layer, and then drying the droplets that form the upper thin film layer on the lower thin film layer to laminate the upper thin film layer over the lower thin film layer.
US08187668B2	Material application method A stage on which a substrate having target discharge areas is placed moves relative to a discharge head unit. When at least one of a plurality of first discharge nozzles of the discharge head unit reaches one of the target discharge areas, the first nozzle discharges a first droplet of fluid material to the target discharge area. When one of a plurality of second nozzles of the discharge head unit reaches the target discharge area to which the first droplet has been discharged, the second nozzle discharges a second droplet of the fluid material to the target discharge area. A first nozzle row of the first nozzles and a second nozzle row of the second nozzles are separated by a predetermined distance in a direction of the relative movement of the stage and the discharge head unit.
US08187666B2	Color filter manufacturing method, color filter, image display device, and electronic device A color filter manufacturing method includes discharging droplets of an ink from a droplet discharge head into a plurality of cells formed on a substrate while moving the substrate with respect to the droplet discharge head, and curing the ink discharged in the cells to form a colored portion within each of the cells. The discharging of the droplets includes prohibiting landing of the droplets in a landing prohibition region formed at a predetermined width from edges of each of the cells in a movement direction of the substrate with respect to the droplet discharge head. The landing prohibition region being arranged so that a relationship 0.5≦L1/L2≦4.5 is satisfied, wherein a value L1 indicates a width of the landing prohibition region and a value L2 indicates an average diameter of the droplets of the ink.
US08187664B2	Metallic pattern forming method, metallic pattern obtained thereby, printed wiring board using the same, and TFT wiring board using the same The invention provides a method of forming a metallic pattern including: (a) forming, in a pattern form on a substrate, a polymer layer which contains a polymer that has a functional group that interacts with an electroless plating catalyst or a precursor thereof; (b) imparting the electroless plating catalyst or precursor thereof onto the polymer layer; and (c) forming a metallic film in the pattern form by subjecting the substrate having the polymer layer to electroless plating using an electroless plating solution, wherein the substrate is treated using a solution comprising a surface charge modifier or 1×10−10 to 1×10−4 mmol/l of a plating catalyst poison before or during the (c) forming of the metallic film. The invention further provides a metallic pattern obtained thereby. Furthermore, the invention provides a printed wiring board and a TFT wiring board, each of which uses the metallic pattern as a conductive layer.
US08187663B2	Measurement, monitoring and control of directed product movements in a Wurster-arrangement and suitable systems A process for measuring, monitoring and/or controlling directed product movements of fluidized products in process systems (1) selected from fluidized bed and spouted bed systems during a spraying process for coating and/or granulation, which includes, with the aid of one or more microwave sensor devices (8), injecting microwave radiation without contact into one or more product streams, receiving the microwave radiation reflected by the particles of the particular product stream and, on the basis of the microwave radiation received, forming and transmitting a measurement signal for the characterization of the product stream, the corresponding use of microwave sensor devices (8) and correspondingly equipped apparatus (1).
US08187661B2	Stent support assembly and coating method A support assembly for a stent and a method of using the same to coat a stent are provided. The support assembly provides for minimum contact between the stent and the support assembly so as to reduce or eliminate coating defects.
US08187659B2	Solid medicament dosage form consumption aid A flavored, lubricating solution is applied to a solid medicament by spray, dipping, or otherwise coating the medicament. This liquid coating masks the often objectionable taste of the medicament while lubricating it, and thus significantly improving the ability to swallow the medicament. The improvement to the swallowing process is dramatically enhanced with significant reduction in gag reflex, general un-palatability and inability to move the dosage form completely through the mouth, palate, and esophagus to the stomach without sticking or lodging at any point in the process. The solution is a mixture of viscosity-adhesion-lubricity ingredients which includes polyols and polysaccharides, preservative agents, flavoring agents (to improve the palatability of the solution) and optional dispensing agents.
US08187648B2	Packaged, developed dough production in low pressure package, and related methods Described are developed, refrigerator-stable, dough compositions in low pressure packages and related methods, wherein the dough compositions contain chemical leavening agents that include an encapsulated basic agent.
US08187647B2	Edible energy composition An energy composition includes a methylated xanthine, a choline derivative, and at least one flavorant in a sufficient amount to render the energy composition palatable. The energy composition may also include vitamins, amino acids, preservatives, and the like.
US08187646B2	Nucleotide pyrophosphatase inhibitor and coenzyme regenerating systems The present invention is related to a method for inhibiting nicotinamide coenzyme degradation in a cereal flour or wheat based product, comprising the addition of an effective amount of nucleotide pyrophosphatase inhibitor to said cereal flour based product, product such as a wheat based product. A further aspect of the present invention is a nucleotide pyrophosphatase having an amino acid N-terminal sequence being (G)IDDRHEVDLPPRP. In another aspect of the present invention, a dough comprising a nucleotide pyrophosphatase inhibitor such as pyrophosphate, and optionally a coenzyme regeneration system comprising at least one NAD(P) or NAD(P)H dependent hydrogenase or dehydrogenase is disclosed. Preferably the coenzyme regeneration system comprises (consists of) mannitol dehydrogenase and D-fructose.
US08187645B2	Yogurt containing confectionery pieces Methods of preparation for cultured milk based products and products prepared thereby are provided wherein a yogurt is produced containing 0.1% to about 5% confectionery filaments. The process involves providing a cooled fermented yogurt base at a temperature of 0° C. to 5° C.; injecting a liquid fat-bearing compound having a total fat concentration of 24% to about 40% into the cooled yogurt base; whereby the liquid fat-bearing compound is shattered into filaments upon contact with the cooled fermented yogurt.
US08187640B2	Low viscosity liquid polymeric delivery system Low viscosity biodegradable polymer solutions of a liquid biodegradable polymer and biocompatible solvent and methods of using the compositions to form a biodegradable liquid polymer implant are provided.
US08187638B2	Preferential killing of cancer cells and activated human T cells using ZnO nanoparticles Here we disclose the response of normal human cells to ZnO nanoparticles under different signaling environments and compare it to the response of cancerous cells. ZnO nanoparticles exhibit a strong preferential ability to kill cancerous T cells (˜28-35X) compared to normal cells. Interestingly, the activation state of the cell contributes toward nanoparticle toxicity as resting T cells display a relative resistance while cells stimulated through the T cell receptor and CD28 costimulatory pathway show greater toxicity in direct relation to the level of activation. The novel findings of cell selective toxicity towards potential disease causing cells indicate a potential utility of ZnO nanoparticle in the treatment of cancer and/or autoimmunity.
US08187636B2	Dosage forms for tamper prone therapeutic agents A dosage form from which a burst release of a drug contained within a tampered dosage form is reduced or retarded by the presence in or on the dosage form of a TPTA (Tamper Prone Therapeutic Agent) trap. If the dosage form has not been tampered with, the TPTA trap does not significantly interfere with the rate of release of the drug from the dosage form. However, if the dosage form has been physically tampered with, the TPTA trap reduces or retards burst release of the drug from the dosage form.
US08187635B2	Pharmaceutical composition containing a pyrrolidone anticonvulsant agent and method for the preparation thereof The present invention relates to a pharmaceutical formulation of solid dosage forms comprising a therapeutically effective amount of a pyrrolidone anticonvulsant agent, and in particular Levetiracetam or a pharmaceutical acceptable salt or derivative thereof, in combination with an effective diluent, such as Dibasic Calcium Phosphate, and additional pharmaceutical excipients, and a process for the preparation thereof by wet granulation.
US08187634B2	Process for the preparation of sevelamer hydrochloride and formulation thereof Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.
US08187633B2	Controlled release coated tablets having prolonged gastric retention The present invention relates to a tablet composed of a core and a coating; said core is formed by two or more layers, wherein at least one of them contains an active agent (3). Wherein one of said layers is formulated as a swellable composition (2), the other one (4) is composed of inert compounds retaining its size at least until the coated tablet is emptied from the stomach. The coating composition is selected from the group comprising water insoluble polymers, ph dependent polymers or mixtures thereof. The active agent is released after rupture of the coating.
US08187632B2	Sustained-release preparations of quinolone antibiotics The present invention relates to an orally administrable preparation comprising a quinolone antibiotic which releases the active compound with a delay.
US08187631B2	Direct compression polymer tablet core The present invention provides a tablet core which comprises at least about 95% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 95% by weight of an aliphatic amine polymer resin The method comprises the step of compressing the aliphatic amine polymer to form the tablet core. The tablet core can further include one or more excipients. In this embodiment, the method of producing the tablet core comprises the steps of: (1) hydrating the aliphatic amine polymer to the desired moisture level; (2) blending the aliphatic amine polymer with the excipients in amounts such that the polymer comprises at least about 95% by weight of the resulting blend; and (3) compressing the blend to form the tablet core. The present invention further relates to a coated tablet comprising an aliphatic amine polymer core wherein the coating is a water based coating.
US08187628B2	Dermal composition for controlling drug flux comprising two acrylic adhesive polymers having different functionalities and different solubility parameters A dermal composition for administration of an amphetamine drug comprising a blend of two or more acrylic-based polymers having differing functionalities so as to modulate the drug solubility in the polymer matrix and the delivery rate of the drug, and methods therefor.
US08187623B2	Medical copolymers Medical copolymers are provided which comprise (a) a polymer backbone comprising (i) a plurality of —C═C— groups within the polymer backbone, (ii) a plurality of —R9— groups within the polymer backbone, wherein R9 comprises a radical-substituted C2-C10 cyclic or heterocyclic group, or (iii) both a plurality of —C═C— groups and a plurality of —R9— groups within the polymer backbone, (b) a plurality of hydrocarbon-based pendant groups along the polymer backbone that comprise a saturated or unsaturated carbon chain of at least four carbons in length, and (c) a plurality of zwitterionic pendant groups along the polymer backbone that comprise a positively charged quaternary ammonium group and a negatively charged phosphate group. Methods of forming such copolymers, medical products that contain such copolymers, and methods of making such medical products are also disclosed.
US08187622B2	Use of nonionic esters in a coating for surfaces coming in contact with blood The present invention relates to methods for coating at least one surface of a medical device for improving the hemocompatibility of said surface. Further, the invention relates to medical devices comprising surfaces, coated with a coating composition containing a nonionic ester formed from an acyclic C3-C6(OH)3-6 polyol and from at least three C12-C26 fatty acids, and further includes at least one hydrophilic group.
US08187620B2	Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents The invention relates generally to a medical device, such as an intravascular stent, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. More particularly, the invention pertains to a medical device having a metal oxide or metal material with a plurality of pores therein disposed on the surface of the medical device and a polymer disposed on the metal oxide or metal material. The invention also relates to medical devices having a surface and an outer region comprising a metal oxide or metal material having a plurality of pores therein and a polymer disposed on the metal oxide or metal material.
US08187617B2	Immediate release compositions and methods for delivering drug formulations using weak acid ion exchange resins in abnormally high pH environments Immediate release compositions and methods for delivering drug formulations using weak acid ion exchange resins in abnormally high pH environments.
US08187615B2	Non-aqueous compositions for oral delivery of insoluble bioactive agents The present invention provides a composition of low water solubility drug, dissolved or dispersed in a non crystalline or low crystalline form in an emulsion type composition of internal oily-solvent and external non-hydrous and water soluble solvent, whereas 1) emulsifying stabilizer comprises low fraction of the composition, and 2) emulsions of mean droplets size below one micron is obtained upon dilution with physiological fluids, and 3) facilitated dispersion of biologically active agents in body fluids is obtained, and more particularly to facilitating biological availability or improving clinical performance.
US08187614B2	Method of using lectins for prevention and treatment of oral and alimentary tract disorders Infectious diseases caused by pathogenic microorganisms resident in the alimentary tract of humans and animals can be prevented and treated by administering to the alimentary tract of the human or animal an effective amount of a composition containing at least one lectin capable of binding to an infective microorganism and diminishing its infective capability of the microorganism. The lectin is administered dispensed in a pharmaceutically acceptable non-toxic vehicle. Peptic ulcer disease caused by infection with H. pylori can be treated by oral administration of lectins that bind to the pathogen. A beneficial ecology of H. pylori can be maintained in infected patients by chronic oral administration of lectins that bind to the pathogen.
US08187613B2	Method of treating allergies using TGF-β1 and allergens The invention provides an allergy prevention method or treatment method, diets and oral drugs enabling prevention/treatment of allergic symptoms without trouble such as systemic adverse reaction, immune deficiency and the like caused by transdermal/intravenous administration of TGF-β. The allergy prevention method or treatment method is to orally administer 100 μg/kg or more of transforming growth factor-beta (TGF-β) relative to a weight of an administration target body and thereby selectively suppress Th2 immune response, while with respect to the diets and oral drugs, the content is set to contain an effective amount of transforming growth factor-beta (TGF-β) therein.
US08187611B2	Anti-peptide antibodies that cross react with protective antigen of Bacillus anthracis and uses thereof The present invention provides a purified peptide comprising at least one of the sequences LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a vaccine, a method to protect or treat an animal from anthrax toxin, a method of making a vaccine and the use of the peptide. The present invention also provides a monoclonal antibody that specifically binds to a peptide sequence comprising at least one of the following peptide sequences: LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a method to protect or treat an animal from anthrax toxin, a method of making a vaccine, a pharmaceutical composition, a method of making a pharmaceutical composition, and the use of the monoclonal antibody.
US08187608B2	Treatment of Fibrosis related disorders The present invention relates to the ability of SAP to suppress fibrocytes. It also relates to the ability of IL-12, laminin-1, cross-linked IgG and IgG aggregates to suppress fibrocytes. Methods and compositions for suppressing fibrocytes using these proteins are provided. These methods are useful in a variety of applications including treatment and prevention of fibrosing diseases such as scleroderma, pulmonary fibrosis and asthma. Finally, the invention includes assays for detecting the ability of various agents to modulate differentiation into fibrocytes. Such assays may also be used to diagnose scleroderma, pulmonary fibrosis, or other fibrosing diseases.
US08187606B2	HPV antigen fusion protein vaccine compositions and uses thereof The present invention provides a fusion protein comprising an immunostimulatory polypeptide and a mutant E7 protein of a human papilloma virus. The present invention also provides a gene encoding the fusion protein, expression vectors containing the gene, a pharmaceutical composition comprising the fusion protein, a method for treating or preventing a human papilloma virus related disease by using the fusion protein and uses of the fusion protein in the preparation of a medicament for the treatment or prevention of the human papilloma virus related disease.
US08187602B2	Anti-histone H1 monoclonal antibody and hybridoma for the production thereof The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.
US08187597B2	Combination therapy for the treatment of ocular neovascular disorders The invention features methods for treating a patient diagnosed with, or at risk of developing, a neovascular disorder by administering a PDGF antagonist and a VEGF antagonist to the patient. The invention also features a pharmaceutical composition containing a PDGF antagonist and a VEGF antagonist for the treatment or prevention of a neovascular disorder.
US08187596B1	Method of treating asthma or allergy by administering an IL-33 receptor antibody Provided herein are methods of modulating IL-33 activity, e.g., for the purpose of treating immune diseases and conditions, as well as methods of screening for compounds capable antagonizing IL-33 signaling.
US08187595B2	Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor-I The present invention provides αVβ3 integrin cysteine loop domain agonists and antagonists (including peptide agonists and antagonists and analogs thereof), along with methods of using the same.
US08187592B2	C1-inhibitor prevents non-specific plasminogen activation by a prourokinase mutant without impeding fibrin-specific fibrinolysis A mutant prourokinase plasminogen activator (M5) was developed to make prouPA less subject to spontaneous activation during fibrinolysis. C1-inhibitor complexes with tcM5. The effect of C1-inhibitor on fibrinolysis and fibrinogenolysis by M5 was determined. Supplemental C1-inhibitor restores the stability of M5 but not that of prouPA. Clot lysis by M5 with supplemental C1-inhibitor showed no attenuation of the rate of fibrinolysis, whereas fibrinogenolysis was prevented by C1-inhibitor. Due to higher dose tolerance of M5 with C1-inhibitor, the rate of fibrin-specific lysis reached that achievable by nonspecific fibrinolysis without inhibitor. Plasma C1-inhibitor stabilized M5 in plasma by inhibiting tcM5 and thereby non-specific plasminogen activation. At the same time, fibrin-specific plasminogen activation remained unimpaired. This unusual dissociation of effects has significant implications for improving the safety and efficacy of fibrinolysis. Methods of reducing bleeding and non-specific plasminogen activation during fibrinolysis by administering M5 along with exogenous C1-inhibitor are disclosed.
US08187590B2	Probiotic, lactic acid-producing bacteria and uses thereof The present invention discloses compositions and methodologies for the utilization of probiotic organisms in therapeutic compositions. More specifically, the present invention relates to the utilization of one or more species or strains of lactic acid-producing bacteria, preferably strains of Bacillus coagulans, for the control of gastrointestinal tract pathogens, including antibiotic-resistant gastrointestinal tract pathogens, and their associated diseases by both a reduction in the rate of colonization and the severity of the deleterious physiological effects of the colonization of the antibiotic-resistant pathogen. In addition, the present invention relates to the utilization of therapeutic compounds comprised of lactic acid-producing bacteria and anti-microbial agents such as antibiotics, anti-fungal compounds, anti-yeast compounds, or anti-viral compounds. The present invention also discloses methodologies for: (i) the selective breeding and isolation of probiotic, lactic acid-producing bacterial strains which possess resistance or markedly decreased sensitivity to anti-microbial agents (e.g., antibiotics, anti-fungal agents, anti-yeast agents, and anti-viral agents); and (ii) treating or preventing bacteria-mediated infections of the gastrointestinal tract by use of the aforementioned probiotic bacterial strains with or without the concomitant administration of antibiotics. While the primary focus is on the treatment of gastrointestinal tract infections, the therapeutic compositions of the present invention may also be administered to buccal, vaginal, optic, and like physiological locations.
US08187587B2	Immunotherapeutic methods targeted toward stratum corneum chymotryptic enzyme The present invention discloses the protease stratum corneum chymotrytic enzyme (SCCE) is specifically over-expressed in ovarian and other malignancies. A number of SCCE peptides can induce immune responses to SCCE, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies.
US08187585B2	Vaccine composition comprising a fibronectin binding protein or a fibronectin binding peptide The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; and at least one iscom matrix complex and/or liposome and/or at least one lipid and at least one saponin, whereby the at least one lipid and the at least one saponin may be in complex, solution or suspension. Further, it regards use thereof for the preparation of a vaccine against a micro organism that comprises at least one fibronectin binding domain. It also relates to a kit of parts comprising at least two compartments, wherein one compartment comprises at least one truncated fibronectin binding protein and/or a fibronectin binding peptide, that comprises at least one fibronectin binding domain, and another compartment comprises an instruction for use and/or an iscom matrix complex and/or an iscom complex and or a liposome. Further it relates to a method for vaccination of an individual.
US08187582B2	Hair styling composition A hair non-permanent styling composition comprising: i) an oligosaccharide comprising 3 to 7 sugar units in which the linkage group between the sugar units is an α1-4 link; and ii) at least one further ingredient selected from the group consisting of a suitable carrier, a styling polymer or a surfactant.
US08187576B2	Plasticizer of natural origin for nail polish The use of at least one carbonate of natural origin as a plasticizer in a film-forming cosmetic composition comprising, in a physiologically acceptable medium, a film-forming polymer and a solvent medium.
US08187575B2	Triazine derivatives as UV absorbers The present invention relates to new compounds of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, and R8 independently from each other are hydrogen; C1-C18alkyl; C2-C18alkenyl; C5-C7, cycloalkyl; C1-C6alkylene-C5-C7, cycloalkyl; R9 is hydrogen; C1-C18alkyl; C2-C18alkenyl; C5-C7cycloalkyl; C1-C6alkylene-C5-C7cycloalkyl; C6-C10aryl; A is —S—; —O— or —NR10—, wherein R10 has the same meanings as R9; X is COOR11; CONR12R13; SO3, R14; or SO2NR15R16, wherein R11, R12, R13, R14, R15, and R16, have independently from each other the same meanings as R9; to their preparation and to their use as UV absorbers in cosmetic and pharmaceutical formulations.
US08187573B2	In vivo detection of apoptosis The invention provides methods and products, such as kits, useful for determining the apoptotic state of cells in an organism, comprising detecting the presence or abundance of at least one caspase affinity labeling agent in the cells of an animal into which at least one caspase affinity labeling agent has been introduced, wherein the presence or abundance of the caspase affinity labeling agent correlates with the apoptotic state of the cells.
US08187572B2	Diabetogenic rat model The present invention provides a method of producing diabetic rats, and a method for identifying compounds that reverse diabetes in said rats.
US08187568B2	Method and plant for the production of synthesis gas from biogas A method and system produce a synthesis gas from a biogas. The method provides a more economic process control and a higher yield. For this purpose hydrogen sulfide and carbon dioxide of the biogas are nearly completely separated in separate cleaning steps before a catalytic conversion of the biogas, wherein hydrogen sulfide is biologically removed by the admixture of oxygen and/or oxidation agents containing oxygen. The oxygen, or the oxidation agent, is dosed such that an excess of oxygen of at least 1.0 vol.-% is present in the cleaned biogas (methane gas). The biogas is concentrated without any dehumidification, heated, and mixed with superheated steam. Due to the excess of oxygen, thermal energy is additionally created during the reforming process by an exothermal oxidation of oxygen contained in the biogas together with hydrogen in the catalyst bed for the endothermal conversion of methane to the synthesis gas.
US08187566B2	Continuous method and apparatus of functionalizing carbon nanotube The present invention relates to a continuous method for functionalizing a carbon nanotube, and more specifically, to a continuous method for functionalizing a carbon nanotube by feeding functional compounds having one or more functional group into a functionalizing reactor into which a carbon nanotube mixture including oxidizer is fed under a pressure of 50 to 400 atm and a temperature of 100 to 600° C. to a subcritical water or supercritical water condition of a pressure of 50 to 40 atm by using a continuously functionalizing apparatus to obtain the functionalized products, such that the functional group of the functional compound can be easily introduced to the carbon nanotube, thereby increasing the functionalized effect of the carbon nanotube and increasing the dispersibility accordingly.
US08187559B2	Heat exchanger system comprising fluid circulation zones which are selectively coated with a chemical reaction catalyst The invention relates to a plate (10a) intended to be integrated in a stack of plates in a heat exchanger system, the plate comprising a plurality of channels (38) distributed in rows (40), each row comprising side walls (42) arranged opposite one another and spaced apart from one another in a first direction (44), so that two directly consecutive side walls delimit one of the channels (38), the rows being arranged opposite one another and spaced apart from one another in a second direction (46) which is perpendicular to the first. Furthermore, in the fluid circulation zone (20) of the plate incorporating the channels (38), only the latter are coated with a catalyst allowing a chemical reaction.
US08187552B2	Apparatus for producing trichlorosilane and method for producing trichlorosilane An apparatus for producing trichlorosilane includes: a decomposing furnace, a heating unit heating the inside of the decomposing furnace, a raw material supplying tube for guiding polymer and hydrogen chloride to be guided to the inner bottom portion of the decomposing furnace, and a gas discharge tube for discharging reaction gas from the top of the reaction chamber provided between the outer peripheral surface of the raw material supplying tube and the inner peripheral surface of the decomposing furnace, a fin, which guides a fluid mixture of the polymer and the hydrogen chloride supplied from the lower end opening of the raw material supplying tube to be agitated and rise upward in the reaction chamber, and is formed integrally with at least one of the outer peripheral surface of the raw material supplying tube and the inner peripheral surface of the decomposing furnace.
US08187551B2	Method and apparatus for manufacturing trichlorosilane An apparatus 1 for manufacturing trichlorosilane includes a decomposition furnace 2 into which polymers and hydrogen chloride are introduced, the decomposition furnace 2 includes: a heating device 11 which heats an interior of the decomposition furnace 2; a reaction chamber 4 which is formed in the decomposition furnace; a center tube 3 which is inserted in the reaction chamber 4 along a longitudinal direction of the reaction chamber and has a lower-end opening portion 3a; raw-material-supply pipes 5 and 6 which supplies the polymer and the hydrogen chloride to the reaction chamber 4 at an exterior of the center tube 3; and a gas-discharge pipe 7 which leads out reacted gas from the center tube 3, the apparatus 1 further includes a fin 14 that leads the polymer and the hydrogen chloride to the lower-end opening portion 3a of the center tube 3 so as to stir the polymer and the hydrogen chloride.
US08187544B2	Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
US08187541B2	Apparatus for detecting target molecules and related methods An apparatus for analysis of a sample and in particular of a biological sample. The apparatus contains a microfluidic chip with dies, adapted to be selectively activated or deactivated by presence of target molecules in the biological sample. The apparatus further contains a light source to emit light for illumination of the microfluidic chip and an optical filter to allow passage of the light from the dies once activated or deactivated by the presence of the target molecules. A method for pressurizing a microfluidic chip is also disclosed, where a chamber is provided, the chamber is connected with the microfluidic chip and pressure is applied to the chamber.
US08187540B2	Concentration monitor method A concentration monitor for monitoring a concentration of a plurality of use solutions, each of the plurality of use solutions being, at least, a concentrate in a diluent, each of the plurality of use solutions having a resistivity which varies as a function of both temperature and an amount of the concentrate contained in a given amount of the diluent. A resistivity probe is adapted for use with at least one of the plurality of use solutions for taking a measurement related to the resistivity of the at least one of the plurality of use solutions. A temperature sensor is adapted for use with the at least one of the plurality of use solutions for taking a measurement related to the temperature of the at least one of the plurality of use solutions. A controller calculates the concentration of the at least one of the plurality of the use solutions based upon a predetermined algorithm using the resistivity and the temperature for the particular one of the at least one of the plurality of use solutions, the algorithm being based upon knowledge of the at least one of the plurality of use solutions being measured.
US08187539B2	Device and method for determining material properties by means of HPLC An assembly for determining material properties and/or material concentrations of components of a sample, containing: a chromatographic separating column with a liquid mobile solvent; means for controlling the temperature inside the separating column between room temperature and 250° C.; means for creating a pressure level which is greater than ambient pressure inside the separating column; and a detector with a sample volume adapted to insert the components of the sample, is characterized in that the mobile solvent contains water to a large extent; means are provided for expanding the mobile solvent from the increased pressure level inside the separating column to the ambient pressure and for producing a phase change of the mobile solvent from the liquid to gaseous state; and means are provided for transferring the gaseous mobile solvent containing the components of the sample into the sample volume of the detector.
US08187538B2	Diluent wells produced in card format for immunodiagnostic testing An immunodiagnostic test card includes a flat planar member and at least one dilution chamber that is supported by the flat planar member. The at least one dilution chamber can be disposed adjacent chambers used for testing a patient sample that are provided on the immunodiagnostic test card or can be provided separately.
US08187533B2	Descenting systems and methods Systems and methods for using a scent elimination device to conceal contraband and then training service animals to determine if an ozone-based scent-removal technique has been used to remove scent from contraband are disclosed. The systems and methods comprise providing a plurality of packages. At least one of the plurality of packages containing a predetermined amount of a contraband substance. Further, the systems and methods comprise generating a gaseous stream of descenting material from a portable device. The gaseous stream of descenting material contains ozone. Further, the systems and methods comprise dispersing the gaseous stream of descenting material over the contraband in a concentration sufficient to eliminate the scent. The descented contraband may be placed in an enclosure for transport. Further, the systems and methods comprise introducing a service animal to the plurality of packages. Finally, the systems and methods comprise rewarding the service animal for the successful detection of the at least one of the plurality of packages containing the ozone-based scent remover.
US08187529B2	Wear resistant alloy and method of producing thereof A wear resistant, high chromium white iron, in an unheat-treated condition has a microstructure substantially comprising austenite and M7C3 carbides. The white iron contains at least one martensite promoter and at least one austenite stabilizer which are present at respective levels to achieve a balance between their effects whereby the white iron has a microstructure characterized by at least one of: i) being substantially free of martensite at interfaces between the austenite and M7C3 carbides; and ii) having a relatively low level of interconnectivity between carbide particles; such that the white iron is substantially crack-free. The white iron may be as-cast or comprise weld deposited hardfacing.
US08187524B2	Apparatus and method for manufacturing absorbent body An apparatus for manufacturing an absorbent body, having a recessed form die formed on a predetermined face of a predetermined member, moving in one direction along a moving path along the predetermined face; a duct disposed in a predetermined position in the moving path, discharging a gas including fluid absorbent fibers from an opening section toward the predetermined face, an absorbent body being formed by suction of the gas through intake holes at a bottom section of the form die to stack into the form die the fluid absorbent fibers included in the gas when the form die passes by the position of the duct. A gap is formed between the predetermined face and the opening section of the duct. A gas pressure inside the duct is lower than a gas pressure outside the duct by suction of the gas from the bottom section of the form die. A first wall is outside the duct. The first wall is spaced from a wall of the duct by a first spacing and spaced from the predetermined face by a second spacing. An outside gas flow along a direction intersecting with the predetermined face and an outside gas flow along the predetermined face is made to reach the gap by the first wall.
US08187510B2	Method for producing granular composition A method for producing a granular composition including the steps of: stirring and granulating a mixture containing not less than 3 parts by weight and not more than 80 parts by weight of a phenol compound represented by the formula (1): wherein R1 is an alkyl group having 1 to 8 carbon atoms, X is an n-valent alcohol residue having 1 to 18 carbon atoms optionally containing a heteroatom, a cyclic group, or a heteroatom and a cyclic group, and n is an integer of 1 to 4, and not less than 20 parts by weight and not more than 50 parts by weight of a binder to obtain a granular agglomerate; and cracking the granular agglomerate at a temperature equal to or lower than the melting point of the binder and equal to or higher than the temperature which is 10° C. lower than the melting point, through a cracking machine equipped with a separation mechanism capable of recovering a granule having a particle size of not more than 5 mm, and a cracking mechanism, to obtain a granule.
US08187507B2	GaN crystal producing method, GaN crystal, GaN crystal substrate, semiconductor device and GaN crystal producing apparatus A method for producing a GaN crystal capable of achieving at least one of the prevention of nucleation and the growth of a high-quality non-polar surface is provided. The production method of the present invention is a method for producing a GaN crystal in a melt containing at least an alkali metal and gallium, including an adjustment step of adjusting the carbon content of the melt, and a reaction step of causing the gallium and nitrogen to react with each other. According to the production method of the present invention, nucleation can be prevented, and as shown in FIG. 4, a non-polar surface can be grown.
US08187502B2	Spin-coatable liquid for formation of high purity nanotube films Certain spin-coatable liquids and application techniques are described, which can be used to form nanotube films or fabrics of controlled properties. A spin-coatable liquid for formation of a nanotube film includes a liquid medium containing a controlled concentration of purified nanotubes, wherein the controlled concentration is sufficient to form a nanotube fabric or film of preselected density and uniformity, and wherein the spin-coatable liquid comprises less than 1×1018 atoms/cm3 of metal impurities. The spin-coatable liquid is substantially free of particle impurities having a diameter of greater than about 500 nm.
US08187500B2	Biphasic inks A biphasic ink comprises a plurality of attractive particles, a plurality of repulsive particles, and a carrier liquid.
US08187498B2	Phosphor, method for manufacturing the same, and light emitting diode A phosphor is formed with a glass coating layer on a surface of a phosphor grain to have improved moisture and/or thermal stability. A method for manufacturing the phosphor comprises preparing phosphor gains excitable by light, and forming a glass coating layer on a surface of each phosphor grain. The glass coating layer may be formed by mixing the phosphor grains with a glass composition; heat-treating a mixture of the phosphor grains and the glass composition to make the glass composition melt and surround the phosphor grains; and cooling and breaking the heat-treated mixture to provide phosphors, each comprising the phosphor grain having the glass coating layer formed on a surface of the phosphor grain.
US08187496B2	Method of preparing metallic oxide phosphor A method for preparing a metal oxide phosphor contemplates preparing a solution including a metal precursor compound and an ionic material and heating the solution under pressure using microwaves.
US08187487B2	Material removal methods employing solutions with reversible ETCH selectivities A method for removing (e.g., etching) different dielectric materials from a semiconductor substrate includes exposing the semiconductor substrate to a solution at temperatures below and at or above a set threshold. Below the threshold temperature, the solution removes one dielectric material (e.g., silicon nitride) faster than it removes another, different dielectric material (e.g., silicon oxide). At or above the threshold temperature, the selectivity of the solution is reversed.
US08187483B2	Method to minimize CD etch bias The present invention provides a method for improving the critical dimension performance during a plasma etching process of a photolithographic substrate having a thin film. A passivation film is deposited onto the photolithographic substrate using a first set of process conditions. The deposited film is etched from the photolithographic substrate using a second set of process conditions. An exposed surface of the photolithographic substrate is etched using a third set of process conditions. During the plasma processing of the photolithographic substrate, the critical dimension performance of the photolithographic substrate is monitored to insure that the target uniformity and feature widths are obtained by adjusting the deposition and etch plasma processing of the photolithographic substrate.
US08187479B2	Manufacturing method of printed circuit board Disclosed is a manufacturing method of a printed circuit board. The method in accordance with an embodiment of the present invention includes: providing a laminated substrate having an insulator as well as a first metal layer and a second metal layer, which are sequentially laminated on one side of the insulator; processing a via hole in the laminated substrate; forming a seed layer on an inner wall of the via hole and on a surface of the second metal layer; plating an inside of the via hole and the surface of the second metal layer with a conductive material that is different from a material of the second metal layer; etching the seed layer and the conductive material, formed on the second metal layer; etching the second metal layer; and forming a first circuit pattern by selectively etching the first metal layer.
US08187474B2	Water-filtering media and filters In at least some embodiments, a system for removing contaminants from fluids includes a fluid inlet and a fluid outlet. The system also includes a fluid pump between the fluid inlet and the fluid outlet and a filter material between the fluid inlet and the fluid outlet. The filter material comprises a dual-valence polymer with negative valence monomer groups and positive valence monomer groups, the negative valence being stronger than the positive valence.
US08187467B2	Parenteral administration of pyrophosphate for prevention or treatment of phosphate or pyrophosphate depletion Phosphate depletion, a physiological condition commonly seen in certain patient populations, including alcoholics, malnourished, acutely ill patients, patients receiving parenteral nutrition, patients being re-fed after prolonged fasting, and dialysis patients, requires intravenous supplementation when oral repletion is not feasible. This invention provides a method and pharmaceutical composition for therapeutic administration of pyrophosphate, instead of phosphate, for phosphate or pyrophosphate repletion. During hemodialysis or peritoneal dialysis significant removal of phosphate and pyrophosphate occurs. Pyrophosphate depletion predisposes patients to vascular calcification. This invention further provides a method and pharmaceutical composition for therapeutic administration of pyrophosphate for phosphate or pyrophosphate repletion by addition of pyrophosphate to hemodialysis or peritoneal dialysis solutions.
US08187464B2	Apparatus and process for desalination of brackish water using pressure retarded osmosis Water from underground and other sources is brackish and not suitable for human consumption. Naturally present dissolved chemicals in water make it brackish. The precipitants and dissolved chemicals need to be separated from water to make it consumable. A combination of aeration systems, filtration systems, crystallizers and hydrophobic membrane carrying filter are used to desalinate the brackish water. Pressure retarded osmosis process using an apparatus is also used to further purify water. Various heat exchange apparatus are used for energy conservation and efficient processing of water in a feasible way. The disclosure enables to purify water and provide a useful technology to eradicate water scarcity.
US08187463B2	Methods for dewatering wet algal cell cultures A method of dewatering algae and recycling water therefrom is presented. A method of dewatering a wet algal cell culture includes removing liquid from an algal cell culture to obtain a wet algal biomass having a lower liquid content than the algal cell culture. At least a portion of the liquid removed from the algal cell culture is recycled for use in a different algal cell culture. The method includes adding a water miscible solvent set to the wet algal biomass and waiting an amount of time to permit algal cells of the algal biomass to gather and isolating at least a portion of the gathered algal cells from at least a portion of the solvent set and liquid of the wet algal biomass so that a dewatered algal biomass is generated. The dewatered algal biomass can be used to generated algal products such as biofuels and nutraceuticals.
US08187460B2	Devices for separating, mixing and concentrating magnetic particles with a fluid The present invention is related to devices for manipulating magnetic particles that are suspended in a fluid, possibly containing a biological entity of interest, the magnetic particles being able to bind the entity of interest, the fluid being contained in a reaction vessel constituted by a large upper compartment with a funnel shape, an elongate lower compartment with a substantially constant cross-section and a closed base. The devices are especially useful in methods for the extraction of nucleic acid to enable them for further processing.
US08187458B2	Oil filter An oil filter assembly is disclosed for a machine, such as an internal combustion engine, that has an oil output port and an oil input port. A mounting plate is fixed with an outer enclosure and is adapted for securing to the machine. The mounting plate is further adapted to conduct oil from the machine into a peripheral portion of the outer enclosure, and then returning oil from a central portion of the outer enclosure back to the machine. Oil may pass from the peripheral portion to the central portion through a primary filter having a first porosity. A pressure-actuated valve is fixed fluidly between the peripheral portion and central portion of the outer enclosure. Oil may pass through the pressure-actuated valve only when an oil pressure differential between the peripheral portion and the central portion of the outer enclosure exceeds a predetermined threshold pressure. A secondary filter has a second porosity greater than the first porosity, and is fixed fluidly between the pressure-actuated valve and the central portion of the outer enclosure.
US08187452B2	Method and system for magnetic recording media A patterned magnetic recording media and method thereof is provided. A recording layer comprises a continuous surface of more-noble elements and less-noble elements, such as CoXYZ, wherein X can be Pt, Pd, Ru, Rh, Ir, Os, or Au, wherein Y can be null or Cr, and wherein Z can be null, Cu, Ta, Ti, O, B, Ag, or TiO2. The recording layer is masked, shielding areas for recording domains and exposing areas between the recording domains. A voltage bias establishes the substrate as an anode in the presence of Pt cathode, in an electrolyte bath. Ions of the less-noble element are anodically removed predominantly from the exposed areas of the recording layer for a controlled time. The controlled time minimizes oxidation of the nobler element and reduces undercutting of the recording domains. The article produced can have separating areas with surfaces substantially formed of the more-noble element.
US08187441B2	Electrochemical pump The invention provides electrochemically-based methods and devices for producing fluid flow and/or changes in fluid pressure. In the methods and devices of the invention, current passes through a divided electrochemical cell. Adjacent compartments of the cell are divided by an ionically conducting separator. Each compartment includes an electrode and an electrolyte solution or ionic liquid. The electrolyte solution(s) or ionic liquid(s) and the ionically conducting separator are selected to obtain the desired relationship between the current through the cell and the fluid flowrate and/or change in fluid pressure.
US08187438B2	Use of an electrophoretic gel provided with a non-adherent polymer film This invention relates to electrophoresis, in particular pre-cast mini gels with a low fluorescent polymer backing that is not adherent to the gel. Use of this type of small gel simplifies blotting procedures, such as Southern and Western blotting, after electrophoresis.
US08187436B2	Sensor deterioration judging apparatus and sensor deterioration judging method A gas sensor controller 190 stops an operation of pumping in or out oxygen that is being performed by a first pump cell 111 in a state that the oxygen concentration (oxygen partial pressure) of a gas to be measured is equal to a status judgment reference value (20%). The gas sensor controller 190 calculates an oxygen pressure in a second measurement chamber 161 on the basis of a second pump current Ip2. If the oxygen pressure in the second measurement chamber 161 is equal to a deterioration judgment reference value, the gas sensor controller 190 judges that the second pump cell 113 is in a normal state. If the oxygen pressure in the second measurement chamber 161 is different from the deterioration judgment reference value, the gas sensor controller 190 judges that the second pump cell 113 is in a deteriorated state.
US08187435B2	Reference electrode The invention provides a reference electrode including a liquid electrolyte containing water, a water soluble organic compound with molecular size and boiling point are both greater than water, and an ionic salt; a solid crystal of the ionic salt in the liquid electrolyte; a metal/metal salt complex layer in contact with the liquid electrolyte; an leading wire connected to the metal/metal salt complex layer; an insulation case for containing the liquid electrolyte; and a nano-porous junction material embedded in the insulation case for contacting the liquid electrolyte, wherein a pore size of the nano-porous junction material is greater than a cation diameter of the ionic salt but smaller than a molecular length of the water soluble organic compound. The solid crystal of the ionic salt is the sediment of part of the ionic salt because the amount of the ionic salt is more than its solubility in the liquid electrolyte.
US08187432B2	Anodizing apparatus An anodizing apparatus for forming an anodized film on the surface of a workpiece (11) made of aluminum or aluminum alloy includes a treatment tank (1) for containing an electrolytic solution, a cathode plate (2) disposed in the treatment tank, a supporting means (3) for supporting the workpiece so as to be immersed in the electrolytic solution, and a power supply (4) for continuously or intermittently applying a short-period bipolar or unipolar pulse voltage or an alternating voltage to between the workpiece and the cathode plate. The cathode plate (2) is arranged in a crosswise direction with respect to the workpiece (11).
US08187429B2	Wastewater treatment apparatus and method with stair-like heat treatment tanks A wastewater treatment apparatus and method with stair-like heat treatment tanks for performing a breakdown process are disclosed, in which the apparatus comprises: a mixing tank, for evenly mixing wastewater with reaction agents and thus forming a mixed solution; a plurality of heat treatment tanks, for enabling the mixed solution to circulate therein while being heating for a period of time so as to perform an organic destruction process upon the mixed solution and thus cause a discharging liquid to be formed; a heat exchanger, for enabling a heat exchanging process between the discharging liquid and the mixed solution to be performed therein; a condensation tank, for receiving and cooling the discharging liquid; a water purifier, for purifying and thus separating the discharging water into a cleaned water and a concentrated liquid for outputting; an agent recycling unit, for electrolyzing the concentrated liquid so as to recycle the reaction agents.
US08187426B2	Steam shower having improved maintenance access A steam shower is provided for supplying steam to a web in a paper machine. The steam shower includes a diffuser assembly mounted to the cross-beam for movement in the direction of the longitudinal axis of the cross beam. The cross-beam defines an interior steam header for connection to a source of steam. The diffuser assembly includes a plurality of separated steam compartments. The diffuser assembly may be part of a steam provision assembly that is also mounted to the cross-beam for movement in the direction of the longitudinal axis of the cross beam. In addition to the diffuser assembly, the steam provision assembly includes a second steam header and steam valve modules.
US08187417B2	Disassembly method for membrane electrode assembly for fuel cell and disassembly method for fuel cell A disassembly method for membrane electrode assembly for fuel cell, and a disassembly method for fuel cell are provided, disassembly methods which are advantageous for the recovery of catalysts that are included in catalytic layers by making structural destruction of the catalytic layers progress by means of expanding a volumetrically-expandable material inside the catalytic layers. In such a state that a catalytic layer includes a volumetrically-expandable material that is capable of expanding volumetrically, the volumetrically-expandable material, which is included in the catalytic layer, is expanded by means of expansion treatment. Next, expansion of the volumetrically-expandable material, which has undergone volumetric expansion in the catalytic layer, is cancelled.
US08187416B2	Interior antenna for substrate processing chamber An antenna for coupling RF energy to a plasma in a process chamber having a wall comprises a coil having a face exposed to the plasma in the chamber. A plurality of standoffs support the coil at a set spacing from the wall of the process chamber, at least one standoff comprising a terminal thorough which electrical power is applied to the coil from an external power source. The terminal comprises a conductor receptacle having a first length L1 and a jacket around the conductor receptacle, the jacket having a second length L2. The length L1 is larger than the length L2. A conductor cup is provided about the standoff having the terminal.
US08187408B2	Method of forming precision microspace, process for manufacturing member with precision microspace, and photosensitive laminated film A method of forming a precision microspace with given configuration and volume; a process for manufacturing a member having a precision microspace with given configuration and volume; etc. There is provided a method of forming a precision microspace by the step of laying a film on a substratum having a precision microscopic depressed portion, comprising the steps of mounting such a substratum on a first stage and setting a second stage covering the outer circumference of the first stage so that the uppermost face of the second stage is higher than that of the first stage; and laying a film on the substratum to thereby obtain a precision microspace with given configuration and volume.
US08187402B2	Method for producing a multidirectional fabric web The invention relates to a method for the continuous production of a multidirectional fabric web. The object of the invention is to create a method for the continuous production of a multidirectional fabric web that has a material layer running in a longitudinal direction and thus has sufficient stability against distortions in the fabric. This object is achieved according to the invention in that a continuous fold-winding process of at least one fiber layer running at an angle to the direction of extension of the fabric web to be produced takes place with the enclosing of at least one material web (1) running freely in the spread-out state in the production direction at least in the fold-winding zone. The invention can be used in the production of fabric webs that are used for example as a reinforcement of high-strength plastics.
US08187400B2	Microtubular honeycomb carbon material obtained by heat-treating cellulose fiber, production method of thereof, microtubular reactor module comprising the microtubular honeycomb carbon material and method for producing the microtubular reactor module Disclosed herein are a microtubular honeycomb carbon material obtained by heat-treating cellulose fiber, a production method thereof, a microtubular reactor module fabricated using the microtubular honeycomb carbon, a method for producing the microtubular reactor module, and a microcatalytic reactor system comprising the microtubular reactor module. A carbon material having a new structure is produced by heat-treating cellulose fiber, and a catalytic reactor system having a new structure is constructed by coating the surface of the carbon material with a metal catalyst. Cellulose carbide, used as the reactor material, is very simple to produce. Because it has a micro honeycomb structure having a large number of microchannels and a large number of mesopores, it can be loaded with a large amount of a catalyst compared to the prior material having the same area, and thus it is useful as a catalyst support, and the reaction efficiency can be maximized. Also, the microcatalytic reactor system can be used in applications including very small steam reformer systems that use biomass fuel such as ethanol, fuel cell reactor systems, VOC and low-concentration-hydrogen treatment systems operable below 200□, micro heat exchangers, and natural gas reformer systems. Thus, the invention is a useful, industrially applicable invention.
US08187397B2	Low density explosive emulsion An explosive emulsion to be used in conjunction with a gas-producing agent, such as sodium nitrite, to form an explosive emulsion with a density between 0.50 g/cm3 and 0.90 g/cm3. The present invention also includes the method for producing the explosive emulsion. The explosive emulsion is stable for at least 96 hours with nitrogen bubbles, having a predetermined dimension range, homogenously distributed. To maintain this low-density explosive emulsion stable, between 84% and 95% by weight of an oxidizing solution is combined with 5% to 16% by weight of a fuel solution. The fuel solution includes solid cacao fat as a stabilizing agent and stearic acid to prevent the combination of the nitrogen bubbles. The method for producing the oxidizing solution includes combining ammonium nitrate, sodium nitrate, thiourea, urea, and water at a temperature between 80 and 90 degrees centigrade. In another step of the method, a fuel solution is produced by combining an emulsifier, oil, diesel No. 2 fuel, solid cacao fat, and stearic acid at a temperature between 40 and 60 degrees centigrade. Then between 84% and 95% of the oxidizing solution is combined with 5% to 16% of the fuel solution.
US08187395B2	Electrical contact having high electrical conductivity made of internally oxidized silver-oxide material for compact electromagnetic relay Disclosed is an electrical contact having high electrical conductivity for a compact electromagnetic relay including an internally oxidized silver-oxide material which is prepared by subjecting an Ag alloy having a composition consisting essentially of, by weight, 5.1 to 9% Sn, 1.5 to 5% In, and 0.005 to 0.06% Bi, with the balance being Ag and unavoidable impurities, to an internal oxidation treatment and then subjecting to a heat treatment for diffusion, aggregation, and growth of precipitated oxides, wherein the internally oxidized silver-oxide material has a metallographic structure such that coarse grains of composite oxides are dispersed and distributed in an Ag matrix, the coarse grains of composite oxides being formed as a result of coarsening of ultra-fine grains of Sn-based oxides and ultra-fine grains of In-based oxides, which are precipitated by the internal oxidation treatment, by the heat treatment for diffusion, aggregation, and growth of the precipitated oxides.
US08187394B2	Soft magnetic powder A powder magnetic core is provided for operating at high frequencies that is obtained by pressure forming an iron-based magnetic powder covered with an insulation film, which has a specific resistance more than 1000, preferably more than 2000, and most preferably more than 3000 μΩm, and a saturation magnetic flux density B above 1.5, preferably above 1.7, and most preferably above 1.9 (T). A method for the preparation of such cores as well as a powder which is suitable for the preparation also are provided.
US08187392B2	R-Fe-B type rare earth sintered magnet and process for production of the same In an R—Fe—B based rare-earth sintered magnet according to the present invention, at a depth of 20 μm under the surface of its magnet body, crystal grains of an R2Fe14B type compound have an (RL1-xRHx)2Fe14B (where 0.2≦x≦0.75) layer with a thickness of 1 nm to 2 μm in their outer periphery. In this case, the light rare-earth element RL is at least one of Nd and Pr, and the heavy rare-earth element RH is at least one element selected from the group consisting of Dy, Ho and Tb.
US08187390B2	Multiple wash zone dishwasher A dishwasher having a tub defining a wash chamber for washing dishes and a dish rack located within the wash chamber. The dishwasher also has a spray arm assembly configured to spray a first flow of wash liquid toward the dish rack, thereby providing a first wash zone. A spray manifold provided within the wash chamber is configured to provide a second flow of wash liquid toward the dish rack, thereby providing a second wash zone.
US08187389B2	Method of removing resist and apparatus therefor A resist removing device 1 functions to remove a resist from a substrate while preventing occurrence of popping phenomenon and at the same time attains reduction in cost of energy for the resist removing and has a simplified constitution. The resist removing device 1 is equipped with a chamber 2 for containing therein a substrate 16 (for example, a substrate having a high-doze ion implanted resist), and with a pressure below the atmospheric pressure, the chamber 2 is fed with ozone gas, unsaturated hydrocarbons and water vapor. The ozone gas may be an ultra-high concentrated ozone gas that is produced by subjecting an ozone containing gas to a liquefaction-separation with the aid of a vapor pressure difference and then vaporizing the liquefied ozone. For cleaning the substrate 16 thus treated, it is preferable to use ultra-pure water. The chamber 2 is equipped with a susceptor 15 for holding the substrate 16. The susceptor 15 is heated to a temperature of 100° C. or below. An example of the means of heating the susceptor is a light source that emits infra-red rays.
US08187374B2	Process for manufacturing clinker with controlled CO2 emission The invention relates to a process for manufacturing clinker from a raw mix, implementing the following: preheating of the raw mix by combustion flue gases; precalcination of the raw mix; and calcination of the precalcined raw mix in a rotary kiln, in which process the precalcination and the calcination in the rotary kiln produce combustion flue gases that contain CO2, in which the combustion flue gases created by the precalcination undergo a CO2-removal treatment without said flue gases mixing with the combustion flue gases created by the calcination in the rotary kiln.
US08187372B2	Ink-jet O/W emulsion ink and ink-jet recording method using the same An ink-jet O/W emulsion ink of the present invention includes an aqueous continuous phase (a), and a nonaqueous discontinuous phase (b), wherein the aqueous continuous phase (a) includes water, at least one pigment and at least one ionic or nonionic surfactant, and the nonaqueous discontinuous phase (b) includes at least one water-insoluble organic material having a hydroxyl group.
US08187369B2	Sorbent activation plate A sorbent activation plate having a first surface, a second surface opposite the first surface, a plurality of reliefs in the first surface, and a plurality of protrusions on the second surface. The sorbent activation plate is structured to attach to a boiler tube such that the plurality of protrusions contact the boiler tube and offset the second surface from the boiler tube.
US08187366B2	Natural gas desulfurization A method for desulfurizing natural gas includes contacting the natural gas with an adsorbent which preferentially adsorbs at least one of hydrogen sulfide, COS, sulfur odorants, or combinations thereof, at a selected temperature and pressure, thereby producing desulfurized natural gas and an at least one of hydrogen sulfide/COS/sulfur odorant/combinations thereof-rich adsorbed component. The adsorbent includes a copper species adapted to form π-complexation bonds and direct metal-sulfur bonds with the at least one of hydrogen sulfide, COS, sulfur odorants, or combinations thereof, and wherein the preferential adsorption occurs by π-complexation and direct metal-sulfur bonding.
US08187365B2	Process for removal of metal carbonyls from a synthesis gas stream The invention provides a process for removal of metal carbonyls from a synthesis gas stream comprising metal carbonyls, the process comprising the steps of: (a) adsorption of metal carbonyls by contacting the synthesis gas stream with solid adsorbent comprising activated carbon and/or hydrophobic zeolite to obtain solid adsorbent enriched in metal carbonyls and a synthesis gas stream depleted of metal carbonyls; (b) desorption of metal carbonyls by contacting the solid adsorbent enriched in metal carbonyls with CO-containing gas comprising at least 0.5 volume % CO to obtain regenerated adsorbent depleted of metal carbonyls and CO-containing gas enriched in metal carbonyls, wherein the temperature at which metal carbonyl desorption takes place is higher than the temperature at which metal carbonyl adsorption takes place.
US08187360B2	Process for the instantaneous control of precipitation of nickel and cobalt present in the leach liquor, by adjusting the pH of the solution The present invention concerns a process for the instantaneous control of the precipitation of nickel and cobalt present in a leach liquor by adjustment of the pH-value. Said leach liquor is obtained by pressurized acidic leaching of laterite ores and additionally contains aluminium, ferric and ferrous iron and chromium among others. The process comprises the following steps: precipitation of aluminium, ferric and ferrous iron, chromium etc. by increasing the pH-value by adding a suitable reagent such as lime and/or limestone, following precipitation of nickel and cobalt by further increasing the pH-value of the liquor, finally separating the precipitate from the low-content nickel and cobalt solution. The nickel and cobalt precipitate can be used for further refinement. In order to keep the process conditions constant, the steps of increasing the pH-value are controlled simultaneously.
US08187354B2	Filtration media for filtering particulate material from gas streams A composite fabric formed by depositing a web of nanofibers electroblown from a first polymer onto a first support web comprising fibers of larger average diameter than the nanofibers spun from a compatible material, in the absence of an adhesive between the webs, and solvent-bonding the webs together.
US08187352B2	Filter A filter bag is longitudinally formed in a frusto-conical shape The filter bag has a plurality of radially extending members that form a propeller shaped cross-section, and a propeller-shaped molded bottom that enhances dust fall from the exterior. A frusto-conically-shaped inner cage facilitates the shape of the filter bag of the filter element.
US08187349B2	Gasification reactor vessel A gasification reactor vessel comprising a combustion chamber in the upper half of the vessel, provided with a product gas outlet at the bottom end of the combustion chamber, at least two burner openings are present in the wall of the combustion chamber, which burner openings are located at the same horizontal level and are positioned diametrical relative to each other and wherein in each burner opening a burner is present, wherein between the wall of the combustion chamber and the wall of vessel an annular space is provided, wherein the wall of the combustion chamber comprises an arrangement of interconnected tubes (vertical arranged or helical coiled), wherein the product gas outlet at the bottom end of the combustion chamber is fluidly connected to a dip-tube, which partly is submerged in a water bath located at the lower end of the reactor vessel, and wherein at the upper end of the dip-tube means are present to add a quenching medium to the, in use, downwardly flowing mixture of hydrogen and carbon monoxide.
US08187348B2	Hydrogen generator A hydrogen generator includes a container with multiple concentric hollow cylinders of chemical hydride fuel disposed within the container. A water vapor source is disposed within the container and operable to deliver water vapor to the cylinders of chemical hydride fuel. Generated hydrogen is provided via a hydrogen output port formed in the container.
US08187343B2	Methods of manufacturing electric double layer capacitor cell and electric double layer capacitor and apparatus for manufacturing electric double layer capacitor cell There are provided methods of manufacturing an electric double layer capacitor cell and an electric double layer capacitor and an apparatus for manufacturing an electric double layer capacitor cell. The method of manufacturing the electric double layer capacitor cell includes preparing first and second electrode sheets by printing electrode material onto conductive sheets, respectively, with the exception of regions to be provided as first and second terminal lead-out portions in the conductive sheets; punching the first and second electrode sheets so as to form a plurality of first and second unit electrodes, respectively, each first unit electrode having the first terminal lead-out portion and each second unit electrode having the second terminal lead-out portion; stacking the first and second electrode sheets with a separator interposed therebetween in order that the plurality of first and second unit electrodes are overlapped; and cutting the first and second electrode sheets being stacked into the first and second unit electrodes.
US08187335B2	Posterior stabilized orthopaedic knee prosthesis having controlled condylar curvature An orthopaedic knee prosthesis includes a tibial bearing and a femoral component configured to articulate with the tibial bearing. The femoral component includes a posterior cam configured to contact a spine of the tibial bearing and a condyle surface curved in the sagittal plane. The radius of curvature of the condyle surface decreases gradually between early-flexion and mid-flexion. Additionally, in some embodiments, the radius of curvature of the condyle surface may be increased during mid-flexion.
US08187332B2	Bone fusion device A bone fusion device provides stability to bones during a bone fusion period. The bones include, for example, the vertebrae of a spinal column. The bone fusion device comprises one or more extendable tabs attached to the bone fusion device by associated rotating means. The bone fusion device is preferably inserted by using an arthroscopic surgical procedure. During arthroscopic insertion of the device, the tabs are pre-configured for compactness. In this compact configuration, the tabs are preferably deposed along and/or within an exterior surface of the bone fusion device. After the bone fusion device has been positioned between the bones, one or more tab(s) are extended. In the preferred embodiment, the position of each tab is related to a positioning element and extending blocks. Typically, the tabs advantageously position and brace the bone fusion device in the confined space between the bones until the bones have fused.
US08187331B2	Expandable vertebral implant and methods of use An implant for insertion between vertebral members in which an inner member, intermediate member, and outer member are concentrically disposed. The inner and outer members may comprise end plates to contact the vertebral members. The outer member may include a tapered interior wall. A locking element is movably contained within an opening that extends through a sidewall of the intermediate member. The intermediate member is displaceable longitudinally in first and second directions relative to the outer member. Displacement of the intermediate member in the first direction tends to force the locking element laterally into contact with the inner and outer members. A biasing member may urge the intermediate member in the first direction. Displacement of the intermediate member in the second direction allows the locking element to be laterally displaced out of contact with the inner member.
US08187327B2	Selectively-expandable bone scaffold An apparatus includes a scaffold configured to be disposed in a bone. The scaffold is configured to move from a first configuration to a second configuration. The scaffold in the second configuration is expanded from the first configuration. A selectively-expandable actuator is configured to be removably disposed within the scaffold. The selectively-expandable actuator is configured to move at least a portion of the scaffold to the second configuration when the selectively-expandable actuator is moved to an expanded configuration. A shape of the selectively-expandable actuator is substantially the same as a shape of the scaffold when the selectively-expandable actuator and the scaffold are in the second configuration. The selectively-expandable actuator configured to be removed from the scaffold when in a collapsed configuration. The scaffold is configured to remain substantially in the second configuration after the scaffold has been expanded by the actuator.
US08187326B2	Attachment of absorbable tissue scaffolds to fixation devices The present invention relates to tissue scaffold implant devices useful in the repair and/or regeneration of diseased and/or damaged musculoskeletal tissue and that include a tissue scaffold component fixedly attached to a scaffold fixation component via a polymeric adhesive layer, and to methods of making such tissue scaffold implant devices.
US08187316B2	Implantable graft device having treated yarn and method for making same An implantable graft device having treated yarn is disclosed. The device includes a graft body forming a lumen defining a longitudinal axis and having proximal and distal ends. The graft body is constructed from a woven fabric having warp yarns aligned in a first direction and a weft yarns aligned in a second direction. At least one of the weft yarns and the warp yarns has an agent applied thereto defining treated yarns of the graft body.
US08187308B2	Internal joint distraction method An internal joint distraction device provides articulation to an articulating bone joint between an upper bone structure and a lower bone structure. The device includes a medial plate shaped to at least partially conform to a medial side of a bone structure of a limb and includes a lateral plate shaped to at least partially conform to a lateral side of a bone structure of a limb. Each of the medial and lateral plates may include a longitudinal length sufficient to extend from the upper bone structure to the lower bone structure thereby spanning at least a portion of the joint. Each plates includes at least one proximal connection feature formed therein for connecting to the upper bone structure and at least one distal connection feature formed therein for connecting to the lower bone structure. An axle extends from one of the connection features on the medial plate to one of the connection features on the lateral plate. The axle extends through one of the upper and lower bone structures in a manner that said one of the upper and lower bone structures pivots about the axle relative to the other of the upper and lower bone structures.
US08187306B2	Interspinous process spacers Interspinous implants including a spacer configured to fit between first and second adjacent spinous processes of a human spine, to maintain a minimum separation between the spinous processes. An implant also includes a fixation portion coupled to the spacer, in which the fixation portion engages at least one spinous process to hold the spacer in a stable position relative to the spinous process. An implant may be monolithic, non-fillable, and may be inserted between the spinous process from a lateral approach. The fixation portion may be configured as a bracket which can substantially encircle the spinous process, or as flanges which engage lateral sides of the spinous process(es). The spacer may be resilient, and may be expandable along the anterior/posterior direction between the spinous processes. An implant may provide resilient resistance during extension, and/or a uniform extension stop between the spinous processes.
US08187305B2	Methods and apparatus for deploying spinous process constraints A surgical tool for deploying an implant includes an elongate outer shaft having a proximal end, a distal end and a central channel therebetween. An elongate inner shaft is at least partially slidably received in the central channel and an actuator mechanism is operatively coupled with either the outer or inner shaft. The tool also includes a piercing element that is coupled with the outer shaft and releasably coupled with the implant.
US08187304B2	Facet fusion system A device including a side wall defining an inner space; a lock mechanism; a pivot post; and a securement post where the device is a facet joint fusion cage; and a facet joint distractor is capable of engaging the lock mechanism via a lock and key arrangement. A method of using such a device includes positioning the facet fusion cage in the facet joint of a patient in need of facet joint fusion; and moving the securement post to a locked position.
US08187303B2	Anti-rotation fixation element for spinal prostheses Prostheses, systems, and methods are provided for replacement of natural facet joints between adjacent vertebrae with vertebral prostheses. A portion of the vertebral prosthesis includes anti-rotation and/or anti-pullout elements to prevent or reduce prosthesis fastener rotation or pull out as a result of torques applied to the prosthesis. Various tools and methods aid the process of surgically adding the vertebral prosthesis to a patient's vertebra.
US08187299B2	Methods and apparatus for cardiac valve repair The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment.
US08187296B2	Apparatus and method for developing an anatomic space for laparoscopic hernia repair and patch for use therewith An apparatus for creating an anatomic space in tissue in a body comprises an introducer and a sheath. The tubular sheath may surround the introducer, and may have a weakened region along its longitudinal axis. A handle may be provided on the sheath. The handle may be adapted to be pulled proximally to separate the weakened region and allow the sheath to be removed from the introducer. The sheath may be secured to the introducer via detents or latches on the handle.
US08187288B2	Re-shapeable medical device A medical device enables a user to bend it into a shape to suit a specific patient need or to orient efficiently the medical device for use. The medical device includes an elongate member, a mechanism, and an actuator. The mechanism is disposed at the distal portion of the elongate member. The actuator is at least partially disposed within the elongate member and coupled to the mechanism for actuating the mechanism relative to the elongate member. The elongate member is capable of being bent into a shape by the user and of retaining the shape during use. The shape may include multiple bends, in multiple directions, as needed for an application. Thereafter, the elongate member is capable of being bent into a second shape by the user and of maintaining the second shape during use.
US08187287B1	Anti-backup mechanism An anti-backup mechanism for constraining operating components in an operating mechanism to complete first and second strokes of reciprocal linear motion.
US08187283B2	Reusable orthopaedic instrument having drain holes A reusable orthopaedic instrument includes a reusable orthopedic trial having a first outer surface and a second outer surface that is opposite the first outer surface. The second outer surface includes a plurality of sidewalls extending outwardly therefrom to form a cavity. A drain hole is formed in the second outer surface at a location within the cavity. The drain hole extends through the reusable orthopaedic trial from the second outer surface to the first outer surface. Further, the second outer surface slopes downwardly from the plurality of sidewalls toward the drain hole.
US08187282B2	Ancillary tool for positioning a glenoid implant The ancillary tool according to the invention comprises a plate which defines a convex surface intended to bear against the glenoid cavity of a patient's scapula and which forms a directional guide for a drilling, fashioning or like member. To allow the surgeon to apply this member in a chosen direction, the tool comprises means for adjusting the position of the guide with respect to the plate.
US08187281B2	Variable angle targeting device An orthopedic device includes a targeting member, an elongated guiding member, and an adjustment member. The targeting member has an elongated body along a first longitudinal axis and can be coupled to an intramedullary implant such that the first longitudinal axis is parallel to the intramedullary implant. The targeting member includes a first bore extending along a second longitudinal axis t1hrough the elongated body, the first bore having a cross-section elongated in the direction of the first longitudinal axis. The first and second longitudinal axes define a first plane. The elongated guiding member passes through the first bore and is pivotable relative to the first longitudinal axis. The adjustment member is coupled to the elongated body and operable to change an orientation of the guiding member relative to the first longitudinal axis in the first plane.
US08187280B2	Knee joint prosthesis system and method for implantation A system for cooperating with an elongated IM member during preparation of a bone for receiving a prosthesis can include a scaffold, skeleton or frame. An alignment assembly can be selectively coupled to the frame. The alignment assembly can cooperate with the IM member to position the frame relative to the bone. A cutting block can be selectively coupled to the frame. According to other features, a posterior stabilized (PS) box guide assembly can have a PS box guide attachment portion that selectively couples with the first attachment portion of the frame. A posterior foot can selectively couple with a second attachment portion on the frame. The posterior foot can be positioned to occupy space of a joint line in an installed position.
US08187278B2	Photodynamic cellular and acellular organism eradication utilizing a photosensitive material and benzalkonium chloride The invention relates to a method of photoeradication of cellular and acellular organisms including the steps of providing a surface acting agent containing benzalkonium chloride in association with a cellular or acellular organism, the surface acting agent disorienting a membrane structure so that said membrane no longer functions as an effective osmotic barrier; providing a photosensitive material in association with the cellular or acellular organism; and applying light in association with the cellular or acellular organism to cause a disruption of the organism. The method according to the present invention may be utilized in invitro and invivo treatment protocols for infections, sterilization procedures, cancer cell eradication, virus and fungus eradication, spore eradication, and biofilm organism eradication. Additional aspects of the invention include particular combinations of photosensitive materials and surfactants for use in photodynamic therapies.
US08187277B2	Translational occipital vertebral fixation system An occipital plating system includes a fixation assembly with a plate and a coupling member extending from a respective one of opposite lateral portions of the plate. The coupling members include a channel to receive a connecting element extending from the spinal column. The coupling members are rotatable and translatable relative to the plate.
US08187274B2	External fixator An external fixator system includes a fixation bar, a fixation pin, and a clamp assembly. The clamp assembly includes a first jaw pair, a second jaw pair, and a first spring insert. The first jaw pair has a first upper jaw component and a first lower jaw component that collectively define a first passage configured to receive the fixation bar. The second jaw pair has a second upper jaw component and a second lower jaw component that collectively define a second passage configured to receive the fixation pin. The first spring insert is positioned within the first passage and interposed between the first upper jaw component and the first lower jaw component. Advancement of the fixation bar into the first passage causes deflection of the first spring insert.
US08187267B2	Ablation catheter with flexible tip and methods of making the same A flexible tip electrode for an ablation catheter and methods for making the same are disclosed. The electrode has a surface configuration that improves flexibility of the electrode. Also, the surface configuration may allow electrode lengthwise freedom of movement, such that the electrode may be shortened when pressed against the target tissue. A coil may be located in the electrode to bias the electrode toward a predetermined configuration.
US08187266B2	Surgical probe and methods for targeted treatment of heart structures A surgical probe and methods for targeted treatment of structures of the heart with heat and radiofrequency energy. The probe which is designed to operated by hand has a elongate member with a handle and an energy-delivering member in an adjustable loop configuration. The control placed on the handle allow the user to alter the length of the loop configuration of the energy-delivering member and to thus place energy-delivering elements located on the energy-delivering member at selected or targeted portions of the heart or structures within the heart. The elongate member is conformable and can be bent into different configurations to allow additional targeted treatment of the particular portions of the heart.
US08187263B2	System and method for return electrode monitoring A return electrode monitoring (“REM”) system is disclosed. The REM system includes a return electrode pad having a pair of split electrode pads and a detection circuit coupled to the pair of split electrode pads. The detection circuit and the pair of split electrode pads are adapted to resonate across a predetermined resonance range. The REM system also includes a controller coupled to the detection circuit and configured to provide a sweeping drive signal to the detection circuit across the resonance range. The detection circuit generates a drive signal in response to the sweeping drive signal and the controller determines a complex impedance across the at least one pair of split electrode pads as a function of the drive signal.
US08187260B1	Variable cryosurgical probe planning system A cryosurgical system for assisting an operator in placing and operating cryosurgical probes in the prostate of a human patient. The cryosurgical system includes a computer system being programmed with software capable of performing the following steps: a) capturing a plurality of transverse views of the prostate; b) capturing a sagittal view of the prostate; c) outlining the capsule of the prostate, the urethra and the rectal wall of the patient with the assistance of the operator, utilizing the captured plurality of transverse views and the captured sagittal view; d) constructing a 3-dimensional model of the prostate, the urethra and the rectal wall utilizing the outlines of step c), above; and, e) utilizing the 3-dimensional model of the prostate, the urethra and the rectal wall to determine i) the number of cryosurgical probes to be utilized; ii) probe settings; and, iii) probe placement positions. The resultant ice thus produced by the cryosurgical probes is optimized for a specific patient.
US08187252B2	Shape memory system with integrated actuation using embedded particles A shape memory material with integrated actuation using embedded particles. One embodiment provides a shape memory material apparatus comprising a shape memory material body and magnetic pieces in the shape memory material body. Another embodiment provides a method of actuating a device to perform an activity on a subject comprising the steps of positioning a shape memory material body in a desired position with regard to the subject, the shape memory material body capable of being formed in a specific primary shape, reformed into a secondary stable shape, and controllably actuated to recover the specific primary shape; including pieces in the shape memory material body; and actuating the shape memory material body using the pieces causing the shape memory material body to be controllably actuated to recover the specific primary shape and perform the activity on the subject.
US08187251B2	Methods of treating cardiac arrhythmia Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a patient's body. Aspects of the invention can be used in a wide variety of applications, but certain embodiments provide minimally invasive alternatives for treating atrial fibrillation by delivering a tissue-damaging agent to selected areas of the heart. One exemplary embodiment of the invention provides a method of treating cardiac arrhythmia. This method includes positioning a distal tissue-contacting portion of a body in surface contact with a tissue surface of cardiac tissue; detecting the surface contact between the tissue-contacting portion and the tissue surface; and thereafter, injecting a tissue-ablating agent into the cardiac tissue through the tissue-contacting portion of the body.
US08187247B2	Multi-configurable absorbent article An absorbent article is provided with closure means for securing the article about the waist of a wearer. The article may be worn in a belt type configuration or a slip type configuration. Belt means are provided which are maintained in a retracted position along a rear panel of the article. Releasable attachment means allow the belt to be extended partially or fully. Fasteners on the front panel may be secured to the respective belt means in a slip type configuration, in which the belt means are in a partially or fully retracted configuration. A belt type configuration may be created in a fully extended configuration of the respective belt portions, in which the belt ends may be fastened to each other about the waist of a wearer. The article may have a substantially constant or same size in both the slip or belt type configurations.

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