Document Document Title
US08102143B2 Electric drive unit
Electric drive units comprising a common active part having a stator and a rotor, which has windings and/or permanent magnets for a drive function and an energy transmission function, enable the rotor winding that is provided for energy transmission to be used to allow position detection at a low additional cost. For this purpose, a power converter in the rotor, which provides the output of electrical energy for the energy transmission function, impresses an alternating voltage into the rotor winding, said voltage being detected in the stator and allowing the rotor position to be determined.
US08102142B2 Double ended inverter system for a vehicle having two energy sources that exhibit different operating characteristics
A double ended inverter system for an AC electric traction motor of a vehicle is disclosed. The inverter system serves as an interface between two different energy sources having different operating characteristics. The inverter system includes a first energy source having first operating characteristics associated therewith, and a first inverter subsystem coupled to the first energy source and configured to drive the AC electric traction motor. The inverter system also includes a second energy source having second operating characteristics associated therewith, wherein the first operating characteristics and the second operating characteristics are different, and a second inverter subsystem coupled to the second energy source and configured to drive the AC electric traction motor. In addition, the inverter system has a controller coupled to the first inverter subsystem and to the second inverter subsystem. The controller is configured to influence operation of the first inverter subsystem and the second inverter subsystem to manage power transfer among the first energy source, the second energy source, and the AC electric traction motor.
US08102138B2 Electric power steering apparatus and method of assembling the same
A motor control apparatus includes a steering column having inserted therein a steering shaft to which steering torque is transmitted, a reduction gear box coupled to the steering shaft, and an electric motor that transmits a steering assisting force to the steering shaft via a reduction mechanism in the reduction gear box. The electric motor and its control unit including a control board mounted with a control circuit, are provided side by side in the reduction gear box. A connection terminal of the electric motor is electrically connected to the control unit directly. This minimizes a connection distance between the control unit and the electric motor.
US08102137B2 Method of detecting a useful signal
A method of detecting a useful signal from a measurement signal that is overlaid by at least one interference signal for use in a control or regulating device, where the interference signal occurs with at least one known interference signal frequency. The method including the steps of detecting the measurement signal, performing a Fourier transformation on the measurement signal with reference to the interference signal frequency to detect the interference signal amplitude and phase, detecting the interference signal on the basis of the interference signal amplitude and phase, and removing the interference signal from the measurement signal to detect the useful signal. The Fourier transformation is performed only with reference to the known interference signal frequency to simplify the computation making it possible to detect the useful signal in real time.
US08102136B2 Simultaneous zero verification for motors in a printing press
A method for determining accuracy of an actual position of a plurality of independent motors in a printing press is provided. The method includes commanding each of the plurality of motors in the printing press via a controller to move a desired initial position, comparing an actual position of each motor to the desired initial position of each motor, determining if the actual position of each motor is within a predetermined tolerance of the desired initial position, and resetting any motor outside the predetermined tolerance to be within the predetermined tolerance. A printing press is also provided. The printing press includes a plurality of printing press components and a plurality of motors. Each motor drives at least one of the printing press components and each of the motors has a desired initial position. The printing press also includes a position detector for determining an actual position of the motor with respect to the desired initial position of the motor.
US08102134B1 Mobile robot with hydraulic mechanism
A mobile robot along with a method and system for a mobile robot including a hydraulic powered mechanism operably connected to the mobile robot for movement of the hydraulic powered mechanism with respect to the mobile robot.
US08102132B2 Starting apparatus for at least two synchronous machines
A starting apparatus is disclosed for at least two synchronous machines, which starting apparatus includes an exciter unit which is provided for each synchronous machine and is associated with the respective synchronous machine. Each exciter unit can be connected to the field winding of the associated synchronous machine. A superordinate control unit is provided, with the superordinate control unit being connected via a communication link to each exciter unit. Furthermore, the starting apparatus includes at least one stator feed unit and at least one switching device, which is provided for each stator feed unit and is associated with the respective stator feed unit, in which case the respective switching device can be connected to the associated stator feed unit, the respective switching device can be connected to at least one synchronous machine, and the switching devices can be connected to one another when there are a plurality of switching devices. The exciter units can be connected to one another via a ring communication link. Each stator feed unit can be connected to the ring communication link. Each stator feed unit can also be connected via a communication link to an associated switching device, and exciter units which are associated with the stator feed units can be each connected via a communication link to a switching device.
US08102131B2 Yarn-tensioning device and arrangement and method for operating a creel
The invention relates to a yarn-tensioning device for producing a specific thread pull on a thread (5) that is unwound from a winding point (7) of a creel (2) and is guided to a warping machine arrangement (1). Said yarn-tensioning device comprises a rotating body (18) which is at least partially wound round by threads and an electric motor (19) which is connected to the rotation body. Said motor (19) is equipped with at least one brake transistor (20) for discharging excess energy produced when the generator of the motor is operated, said brake transistor being able to convert generator energy, arising when the generator is operated, into heat.
US08102130B2 Electric power distribution system using low voltage control signals
An electrical power distribution system for efficiently installing electrical lights, devices, and power outlets to selectively energize or de-energize an electrical load in a building or structure. The electrical power distribution system comprises a control module installed in a building comprising the controlled output that is selectively energized by controlling a latching relay connected to an AC supply source and a load to be energized. Some embodiments further comprise an electronic switch in parallel with a relay. In addition, other embodiments include an electronic switch in parallel with a relay controlled by the same control signal to energize a load, where the electronic switch is energized before the contacts of the relay close and the electronic switch is de-energized after the contacts of the relay open. In an exemplary embodiment the load may be controlled and its ON/OFF status may be known at a distance of at least one mile with a pair of wires, AWG #24 or smaller diameter.
US08102126B2 Light emitting device and production system of the same
To provide a light emitting device without nonuniformity of luminance, a correcting circuit for correcting a video signal supplied to each pixel to a light emitting device. The correcting circuit is stored with data of a dispersion of a characteristic of a driving TFT among pixels and data of a change over time of luminance of a light emitting element. Further, by correcting a video signal inputted to the light emitting device in conformity with a characteristic of the driving TFT of each pixel and a degree of a deterioration of the light emitting element based on the over-described two data, nonuniformity of luminance caused by a deterioration of an electroluminescent layer and nonuniformity of luminance caused by dispersion of a characteristic of the driving TFT are restrained.
US08102123B2 External resonator electrode-less plasma lamp and method of exciting with radio-frequency energy
Described is an electrode-less plasma lamp comprising a gas-fill vessel, a gas-fill contained within the gas-fill vessel, an RF electromagnetic radiation source, an RF electromagnetic resonator, an output probe that couples RF energy from the RF electromagnetic resonator to the gas-fill vessel, an input probe that couples RF energy from the RF electromagnetic radiation source to the resonator, and a grounding strap that holds a metal veneer surrounding the resonator and a portion of the gas-fill vessel at RF ground. Also described are many variations of the electrode-less plasma lamp, non-limiting examples of which include embodiments that employ other probes in a Dielectric Resonant Oscillator to drive the lamp, a lamp employing more than one resonator per gas-fill vessel, and many methods of improving light-harvesting, including raising the gas-fill vessel away from the resonator via a coaxial transmission line, and collecting light with an optical reflector.
US08102121B2 Single-ended ceramic discharge lamp
A single-ended ceramic discharge lamp is described which has an integral optical surface such as a parabolic or elliptical reflector. The single-ended configuration eliminates the need for the mounting structures found in double-ended lamps that can interfere with the light emitted from the lamp, particularly in focused beam applications.
US08102120B2 Plasma display panel
A plasma display panel that includes a first substrate and a second substrate facing each other, a plurality of address electrodes disposed on the first substrate, a plurality of display electrodes disposed on one side of the second substrate facing the first substrate in a direction crossing the address electrodes, and red, green, and blue phosphor layers disposed in a discharge space between the first and second substrates. The green phosphor layer includes a green phosphor and an inorganic pigment absorbing a wavelength of about 580 nm to about 640 nm. The plasma display panel includes a green phosphor layer having a reduced decay time and good color purity characteristics, as well as excellent luminance, discharge, and life-span characteristics.
US08102118B2 White organic light emitting device and color display apparatus employing the same
An organic light emitting device (OLED) having increased light output efficiency and a wide color gamut, and a color display apparatus employing the OLED, includes: a substrate; a reflective electrode formed on the substrate; an organic light emitting layer formed on the reflective electrode; a semi-transparent or transparent electrode formed on the organic light emitting layer; and an optical path control layer formed on the semi-transparent or transparent electrode and formed of a light transmitting material. In the OLED, resonators are formed between the reflective electrode and the semi-transparent or transparent electrode, between the reflective electrode and the top surface of the optical path control layer, and between the top surface of the semi-transparent or transparent electrode and the top surface of the optical path control layer, respectively, therefore, as an optical mode output to the exterior of the optical path control layer, at least two multiple resonances are generated.
US08102115B2 Organic EL display device and manufacturing method thereof
An organic EL display panel which does not impair a sealing effect and ensures a smooth edge portion when individual organic EL display panels are separated from a mother panel on which a plurality of organic EL display panels are formed is provided. A mother panel is formed by adhering a mother element substrate and a mother sealing substrate by way of an adhesive material sheet. In separating the mother panel into individual organic EL display panels, laser beams are radiated to the mother panel along separation lines so as to lower an adhesive strength of the adhesive material sheet at such portions. Thereafter, scribing is applied to the mother panel along the separation lines. Due to such a constitution, it is possible to realize an organic EL display panel without lowering a sealing effect and ensuring smooth appearance.
US08102114B2 Method of manufacturing an inverted bottom-emitting OLED device
A method of making an inverted bottom-emitting OLED device, comprising: providing a substrate; providing one or more first electrodes driven by n-type transistors on the substrate; providing an electron-transporting layer over the substrate and first electrode(s), wherein the electron-transporting layer comprises an n-type inorganic semiconductive material with a resistivity in the range of 1 to 105 ohm-cm and a bandgap greater than 2.5 eV; providing an organic light-emitting layer over the electron-transporting layer; providing a hole-transporting layer over the organic emitting layer; and providing a second electrode over the hole-transporting layer.
US08102110B2 Lamp with outer bulb
A lamp with an outer bulb in which a base (30) includes a base main body (32) having a contact terminal (31) electrically connected with a receptacle and an attaching member (33) fitted to the base main body (32) in a state of retaining the lamp main body (10) and an outer bulb (20), the attaching member (33) has an insertion hole (34) formed therethrough for inserting and retaining a pinch seal (14), and a flange (36) for abutment with the opening end (21) of the outer bulb formed at the outer peripheral surface (35) thereof, and a joint portion (40) is formed for engaging the outer peripheral surface of the attaching member (33) and the inner peripheral surface (23) of the outer bulb (21). An adhesive injection port (38) is opened to the bottom of the attaching member for filling the adhesive to the joint portion (40) in a state of mounting the outer bulb, thereby improving the commercial value by making the adhesive deposited to the insertion hole portion invisible externally, as well as preventing the outer bulb from detachment and mitigating inventory control depending on the type of the bases.
US08102108B2 Low voltage electron source with self aligned gate apertures, fabrication method thereof, and devices using the electron source
A method of fabricating an electron source having a self-aligned gate aperture is disclosed. A substrate is deposited on a first conductive layer. Over the first conductive layer an emitter layer is deposited. The emitter layer includes one or a plurality of spaced-apart nano-structures and a solid surface with nano-structures protruding above the surface. An insulator is conformally deposited over the emitter layer surface and forms a post from each protruding nano-structure. A second conductive layer is deposited over the insulator and the second conductive layer and the insulator are removed from the nano-structures such that apertures are formed in the second conductive layer and at least the ends of the nano-structures are exposed at the centers of said apertures.
US08102105B2 Spark plug
A spark plug in which the rising of a ground electrode is more reliably restrained. The spark plug includes a ground electrode having a core portion extending from a proximal end section toward a distal end section via a bent section, a heat transfer portion extending from the proximal end section toward the distal end section via the bent section, and an external layer located externally of the core portion and the heat transfer portion and extending from the proximal end section to the distal end section via the bent section. As viewed on a section of the ground electrode taken orthogonally to a direction along which the ground electrode extends, at least at an intermediate position of the bent section with respect to the direction, the center of the core portion is offset toward a center electrode from the center of the heat transfer portion.
US08102104B2 Front-side filter and plasma display panel device including the front-side filter
Provided is a front-side filter which can be easily attached to a cover of a display device, but is difficult to detach from the cover even after long term use and further provided is a PDP device including the same filter. The front-side filter includes a filter base having at least one function among a near-infrared ray shielding function, and a neon light shielding function, and an electromagnetic wave shielding function; and an antireflective layer with an edge pattern, formed on a side of the filter base in such a way that the entire edge portion or a part of the edge portion of the filter base is exposed through the edge pattern to provide a fixing means formed in the edge pattern. The plasma display panel device includes a case, a cover for covering an upper surface of the case, a driving circuit board enclosed by the case, a panel assembly disposed on the driving circuit board and enclosed by the case, and a front-side filter including a filter base having at least one function among a near-infrared ray shielding function, and a neon light shielding function, and an electromagnetic wave shielding function; and an antireflective layer with an edge pattern, formed on a side of the filter base in such a way that the entire edge portion or part of the edge portion of the filter base is exposed through the edge pattern to provide a fixing means formed in the edge pattern.
US08102097B2 Electrostatic acting device including an electret film
An electrostatic acting device in which leakage of charge from an electret film is suppressed. The electrostatic acting device comprises a movable electrode section (20) having a movable electrode (22), a fixed electrode section (10) having an electret film (12) opposed to the movable section (20) at a predetermined distance and capable of storing charge and a conductive layer (14) formed on a predetermined region on the upper surface of the electret film (12), and an insulating film (13) interposed between the electret film (12) and the conductive layer (14).
US08102096B2 Closely spaced electrodes with a uniform gap
An improved design for maintaining separation between electrodes in tunneling, resonant tunneling, diode, thermionic, thermo-photovoltaic and other devices is disclosed. At least one electrode 1 is made from flexible material. A magnetic field B is present to combine with the current flowing in the flexible electrode 1 and generate a force or a thermal expansion force combined with a temperature distribution that counterbalances the electrostatic force or other attracting forces between the electrodes. The balancing of forces allows the separation and parallelism between the electrodes to be maintained at a very small spacing without requiring the use of multiple control systems, actuators, or other manipulating means, or spacers. The shape of one or both electrodes 1 is designed to maintain a constant separation over the entire overlapping area of the electrodes, or to minimize a central contact area. The end result is an electronic device that maintains two closely spaced parallel electrodes in stable equilibrium with a uniform gap therebetween over a large area in a simple configuration for simplified manufacturability and use to convert heat to electricity or electricity to cooling.
US08102091B2 Interior permanent magnet motor including rotor with unequal poles
An electric machine includes a stator and a rotor core including a first rotor portion positioned adjacent the stator and having an outside diameter. The first rotor portion includes a plurality of elongated slots that define a plurality of poles. The electric machine also includes a plurality of magnets. Each of the plurality of magnets is positioned within one of the slots and arranged such that each of the plurality of poles has a magnetic arc length that is different than a magnetic arc length of any adjacent pole.
US08102085B2 Converter-fed single strand short stroke linear motor
The invention relates to a short stroke linear motor. In order to improve the dynamics of such a short stroke linear motor, the primary part (12) of the motor is provided with a single-strand winding. The primary part (12) and the secondary part (1) have essentially the same pole pitch (tZ=tM). In this way, a very high motor torque is produced in a limited range of displacement. In order to be able to reach a plurality of working positions without an inactive intermediate position, a short stroke linear motor having a double-strand winding is additionally provided, both strands being operated at a phase difference of <90°. The pole pitch of the primary part and the secondary part are again essentially the same.
US08102077B2 Power generation and distribution system configured to provide power to a motor
A power generation and distribution system for providing power to at least one motor configured to drive a wheel of a vehicle includes: at least one power module having at least one generator configured to generate alternating current having a frequency and voltage; a common alternating current bus in electrical communication with the at least one power module through a contactor and configured to receive the alternating current therefrom; at least one power conversion module in electrical communication with the common alternating current bus and configured to convert the alternating current to a specified direct current for delivery to the at least one motor; and a controller configured to communicate with and operatively control at least one of the following: at least one component of the at least one power module; at least one component of the common alternating current bus; at least one component of the at least one power conversion module; or any combination thereof.
US08102071B2 River and tidal power harvester
An energy module comprising an energy absorber; and a mooring system, comprising a wing-shaped polymer shell attached to the energy absorber, the wing-shaped polymer shell designed to utilize the force of a passing current to create a downward force and thereby reduce any upward motion in the energy module; and a mooring cable housed inside the wing-shaped polymer shell and anchored to maintain the energy module in a fore and aft and a side-to-side position to provide stability, and to negate a rotational force on the energy module.
US08102070B2 Float-type energy-generating system
The objective of the invention is to provide a float-type energy-generating system that is able to maintain the system's body stably, without listing, while sailing, even in a strong wind, while efficiently generating electricity. The system includes a hull (4) that allows the system to be suspended underwater or to float on seawater, one or more plates (6) that receive the sea wind so as to allow the hull to sail, and one or more power generators (3) that generate electricity by rotating one or more water turbines that use water as a working medium while the hull sails.
US08102069B2 Water powered electricity generating device
The present invention relates to an apparatus for providing electrical energy from a flowing stream of water by capturing the flowing stream and transferring the captured energy to a rope which passes through a plurality of rotors connected to an electricity generator.
US08102068B1 Buoyant in-stream hydro turbine
A buoyant hydro turbine(31) for capturing and utilizing energy in the currents of flowing water. A driven component(33) produces electricity or other energy is coupled to and supported by a buoyant rotor(64), increasing efficiency and eliminating the need for an independent supporting structure. Tethered in flowing water, the current(71) rotates the rotors(32) and transfers rotatable energy to the central driven component(33) where electricity or other mechanical work is produced. A number of embodiments are adapted for optimizing and maintaining positioning in a stream of moving water. Additional embodiments optimizing the efficiency and effectiveness of the turbine in capturing and utilizing the current's kinetic energy as well as hydrostatic pressure.
US08102065B2 Wave energy converter
A wave energy converter has a shell, a pendulum pivotally positioned in the shell, a magnet thereon, a variable inductor positioned in the shell, a pendulum adjustor for changing a center of gravity of the pendulum, a motion sensor positioned in the shell, a position sensor connected to the pendulum, a rotation sensor connected to the pendulum, and a controller connected to the motion sensor and the position sensor and the rotation sensor. The pendulum has a magnet thereon. The magnet of the pendulum oscillates adjacent the variable inductor. The variable inductor can adjust the inductive capacity.
US08102063B2 Pad structure with a nano-structured coating film
A pad structure includes a copper circuit pattern on a substrate, at least a gold layer stacked on the copper circuit pattern, and a nano-structured coating film stacked on the gold layer.
US08102062B1 Optionally bonding either two sides or more sides of integrated circuits
Methods and systems for forming a variety of integrated circuits, having quite different interfaces and packages, from a single manufactured die. Preferably the die has bond pads for at least a first mode of operation positioned along only two of its four sides, and these bond pads are sufficient to construct a multi-chip module in which the die is functional in the first mode of operation. Many of the pads on these two sides are duplicated on third and/or fourth sides, except that power management circuitry prevents wasteful capacitive current onto whichever of the duplicated pads is not connected out. Optionally the third and/or fourth sides can be used for connections needed for a mode which is not available with two sides only.
US08102061B2 Semiconductor device bonding wire and wire bonding method
It is an object of the present invention to provide a copper-based bonding wire whose material cost is low, having excellent ball bondability, reliability in a heat cycle test or reflow test, and storage life, enabling an application to thinning of a wire used for fine pitch connection. The bonding wire includes a core material having copper as a main component and an outer layer which is provided on the core material and contains a metal M and copper, in which the metal M differs from the core material in one or both of components and composition. The outer layer is 0.021 to 0.12 μm in thickness.
US08102060B2 Electrically conducting connection with insulating connection medium
A device comprising a first component (5) having a first surface (6), a second component (8) having a second surface (9) and a connection layer (7) between the first surface (6) of the first component (5) and the second surface (9) of the second component (8), wherein the connection layer (7) comprises an electrically insulating adhesive and there is an electrically conductive contact between the first surface (6) of the first component (5) and the second surface (9) of the second component (8).
US08102059B2 Interconnect structure for high frequency signal transmissions
A higher aspect ratio for upper level metal interconnects is described for use in higher frequency circuits. Because the skin effect reduces the effective cross-sectional area of conductors at higher frequencies, various approaches are described to reduce the effective RC delay in interconnects.
US08102053B2 Displacement detection pattern for detecting displacement between wiring and via plug, displacement detection method, and semiconductor device
A displacement detection pattern, usable for detection of a relative displacement between a wiring and a via plug, includes a wiring provided between via plugs and a conductor. The conductor is provided in the same layer level as a level at which the wiring is provided and is provided at a predetermined distance from the wiring.
US08102051B2 Semiconductor device having an electrode and method for manufacturing the same
The semiconductor device according to the present invention includes a first insulating layer made of a material containing Si and O, a groove shaped by digging down the first insulating layer, an embedded body, embedded in the groove, made of a metallic material mainly composed of Cu, a second insulating layer, stacked on the first insulating layer and the embedded body, made of a material containing Si and O, and a barrier film, formed between the embedded body and each of the first insulating layer and the second insulating layer, made of MnxSiyOz (x, y and z: numbers greater than zero).
US08102049B2 Semiconductor device including through electrode and method of manufacturing the same
The present invention provides a semiconductor device including at least one of an insulating layer and a semiconductor layer each including a hole formed therein, and a through electrode provided in the hole. In the semiconductor device, the side wall of the hole is constituted of a first region from the opening of the hole to a predetermined position between the opening of the hole and the bottom surface of the hole, and a second region from the predetermined position to the bottom surface of the hole. The through electrode includes a seed layer and a plating layer. The seed layer covers the second region and the bottom surface of the hole without covering the first region. In addition, the plating layer covers the seed layer and at least a part of the first region.
US08102048B2 Electronic device manufacturing method and electronic device
There are provided the steps of forming a bump 104 on an electrode pad 103 provided on a semiconductor chip 101, forming a low-modulus insulating layer 120 on the semiconductor chip 101 and laminating, on the low-modulus insulating layer 120, a high-modulus insulating layer 121 having a higher elastic modulus than an elastic modulus of the low-modulus insulating layer 120, thereby forming a laminated insulating layer 105, exposing a part of the bump 104 from an upper surface of the laminated insulating layer 105, and forming a conductive pattern 106 connected to the bump 104.
US08102046B2 Semiconductor device and method of manufacturing the same
Through heat discharge only by wiring connected to a conventional semiconductor chip, sufficient heat discharge performance may not be achieved in a recent semiconductor device. A semiconductor device according to an aspect of the present invention includes: a flexible substrate including a first main surface and a second main surface; a semiconductor chip; a first heat conductive layer formed on the first main surface of the flexible substrate and electrically connected to the semiconductor chip; and a second heat conductive layer formed on the second main surface of the flexible substrate and electrically insulated from the semiconductor chip.
US08102041B2 Integrated circuit package
Two integrated circuits having circuitry on one of their major surfaces are ground on their opposite major surfaces to reduce their thickness. The ground integrated circuits are then adhered together to form a composite body and placed in a chamber formed within a substrate such as a printed circuit board. Electrical connections are formed between contacts of the integrated circuits and contacts of the substrate. Components may be mounted on the outer surfaces of the substrate.
US08102035B2 Method of manufacturing a semiconductor device
According to the method of manufacturing a semiconductor device, a lead frame is provided wherein the thickness of a tab-side end portion of a silver plating for wire connection formed on each suspending lead 1e is smaller than that of a silver plating formed on each lead. Thereafter, a semiconductor chip is mounted onto a tab. In this case, since the entire surface of the silver plating on the suspending lead 1e is in a crushed state, it is possible to prevent contact of the semiconductor chip with the silver plating when mounting the chip onto the tab. Consequently, in a die bonding process, the semiconductor chip can slide on the tab without contacting the silver plating and thereby making it possible to diminish damage to the semiconductor chip when mounted onto the tab and hence to possibly prevent cracking or chipping of the chip when assembling the semiconductor device.
US08102032B1 System and method for compartmental shielding of stacked packages
A semiconductor device has a first substrate having a plurality of metal traces. At least one electronic component is electrically attached to a first surface of the first substrate. A second substrate has a plurality of metal traces and attached to the first substrate. At least one electronic component is electrically attached to a first surface of the second substrate. An RF shield is formed on the first substrate to minimizing Electro-Magnetic Interference (EMI) radiation and Radio Frequency (RF) radiation to the at least one electronic component on the first substrate to form an RF shield. A mold compound is used for encapsulating the semiconductor device.
US08102031B2 Security element for an integrated circuit, integrated circuit including the same, and method for securing an integrated circuit
An integrated circuit including a substrate; a circuit pattern formed over the substrate; and one or more fences formed around edges of the circuit pattern, each of the one or more fences having a determined electrical resistance which is used to detect the addition of malicious circuitry. Each fence has a determined electrical resistance which is used to monitor the validity of the fence.
US08102026B2 Group-III nitride semiconductor freestanding substrate and manufacturing method of the same
To provide a group-III nitride semiconductor freestanding substrate, with carrier concentration of a peripheral part of a n-type group-III nitride semiconductor freestanding substrate set to be lower than the carrier concentration inside of the peripheral part. In this freestanding substrate, preferably value Δσ obtained by dividing a difference between a maximum value of the carrier concentration and a minimum value of the carrier concentration in a surface of the freestanding substrate by the maximum value of the carrier concentration is greater than 0.05, and the carrier concentration in any place in the surface of the freestanding substrate exceeds 5.0×1017 cm−3.
US08102019B1 Electrically programmable diffusion fuse
A fuse structure for a semiconductor integrated circuit (IC) includes an anode comprising conductive material overlaying a diffusion material disposed within a substrate layer of the IC, wherein the diffusion material is electrically isolated from the substrate layer by at least one p-n junction. The fuse structure can include a cathode comprising conductive material overlaying the diffusion material. The fuse structure further can include a fuse link comprising conductive material overlaying the diffusion material, wherein a first end of the fuse link couples to the anode and a second end of the fuse link, that is distal to the first end, couples to the cathode.
US08102018B2 Nonvolatile resistive memories having scalable two-terminal nanotube switches
A non-volatile resistive memory is provided. The memory includes at least one non-volatile memory cell and selection circuitry. Each memory cell has a two-terminal nanotube switching device having and a nanotube fabric article disposed between and in electrical communication with two conductive terminals. Selection circuitry is operable to select the two-terminal nanotube switching device for read and write operations. Write control circuitry, responsive to a control signal, supplies write signals to a selected memory cell to induce a change in the resistance of the nanotube fabric article, the resistance corresponding to an informational state of the memory cell. Resistance sensing circuitry in communication with a selected nonvolatile memory cell, senses the resistance of the nanotube fabric article and provides the control signal to the write control circuitry. Read circuitry reads the corresponding informational state of the memory cell.
US08102017B2 Image sensor and method for manufacturing the same
An image sensor may comprise circuitry, a first lower electrode, a photodiode, an upper electrode, a second lower electrode, and an upper interconnection. The circuitry may comprise a first lower interconnection and a second lower interconnection over a dielectric of a substrate. The first lower electrode, the photodiode, and the upper electrode may be sequentially formed over the first lower interconnection. The second lower electrode may comprise a passivation layer over the second lower interconnection. The upper interconnection may be formed over the second lower electrode and electrically connected to the upper electrode.
US08102013B2 Lanthanide doped TiOx films
The use of atomic layer deposition (ALD) to form an amorphous dielectric layer of titanium oxide (TiOX) doped with lanthanide elements, such as samarium, europium, gadolinium, holmium, erbium and thulium, produces a reliable structure for use in a variety of electronic devices. The dielectric structure is formed by depositing titanium oxide by atomic layer deposition onto a substrate surface using precursor chemicals, followed by depositing a layer of a lanthanide dopant, and repeating to form a sequentially deposited interleaved structure. Such a dielectric layer may be used as the gate insulator of a MOSFET, as a capacitor dielectric, or as a tunnel gate insulator in flash memories, because the high dielectric constant (high-k) of the layer provides the functionality of a thinner silicon dioxide layer, and because the reduced leakage current of the dielectric layer when the percentage of the lanthanide element doping is optimized.
US08102011B2 Semiconductor device including a field effect transistor and method for manufacturing the same
There is provided a semiconductor device including a field effect transistor. The field effect transistor includes a p-type low concentration region formed over a surface of a substrate, an n-type drain-side diffusion region and an n-type source-side diffusion region formed over a surface of the p-type low concentration region, an element isolation insulating layer, and another element isolation insulating layer. A p-type high concentration region, which has an impurity concentration higher than the impurity concentration of the p-type low concentration region, is formed below the n-type source-side diffusion region in the p-type low concentration region over a range at least from one end, which is opposite to the other end facing to the channel region, of the source-side diffusion region to one end, which is facing to the channel region, of the second element isolation insulating layer, when seen in a plan view.
US08102008B2 Integrated circuit with buried digit line
A method of forming a buried digit line is disclosed. Sacrificial spacers are formed along the sidewalls of an isolation trench, which is then filled with a sacrificial material. One spacer is masked while the other spacer is removed and an etch step into the substrate beneath the removed spacer forms an isolation window. Insulating liners are then formed along the sidewalls of the emptied trench, including into the isolation window. A digit line recess is then formed through the bottom of the trench between the insulating liners, which double as masks to self-align this etch. The digit line recess is then filled with metal and recessed back, with an optional prior insulating element deposited and recessed back in the bottom of the recess.
US08102007B1 Apparatus for trimming high-resolution digital-to-analog converter
A method and apparatus for trimming a high-resolution digital-to-analog converter (DAC) utilizes floating-gate synapse transistors to trim the current sources in the DAC by providing a trimmable current source. Fowler-Nordheim electron tunneling and hot electron injection are the mechanisms used to vary the amount of charge on the floating gate. Since floating gate devices store charge essentially indefinitely, no continuous trimming mechanism is required, although one could be implemented if desired. By trimming the current sources with high accuracy, a DAC can be built with a much higher resolution and with smaller size than that provided by intrinsic device matching.
US08102004B2 Semiconductor device and manufacturing method thereof
A semiconductor device according to an embodiment of the present invention comprises: a semiconductor substrate; a first field-effect transistor formed on the semiconductor substrate, and including a fin constituted by a semiconductor layer having source and drain regions via a channel region in an extending direction, and a gate electrode formed on the channel region via an insulating film; a stress application layer formed on a top surface of the gate electrode, and formed by a conductive material of which a difference between linear expansion coefficients at a temperature of forming a stress application layer and a room temperature is different from a difference between linear expansion coefficients of the fin at the temperature of forming the stress application layer and the room temperature, and a plug layer formed on the stress application layer and above the fin, and made of a conductive material having larger Young's modulus than that of the fin.
US08102003B2 Resistance memory element, method of manufacturing resistance memory element and semiconductor memory device
A resistance memory element which memorizes a high resistance state and a low resistance state and is switched between the high resistance state and the low resistance state by an application of a voltage includes a first electrode layer of titanium nitride film, a resistance memory layer formed on the first electrode layer and formed of titanium oxide having a crystal structure of rutile phase, and a second electrode layer formed on the resistance memory layer.
US08102002B2 System and method for isolated NMOS-based ESD clamp cell
The invention is directed to a protection circuit for protecting IC chips against ESD. An ESD protection circuit for an integrated circuit chip may comprise an isolated NMOS transistor, which may comprise an isolation region isolating a backgate from a substrate, and a first and second doped regions and a gate formed on the backgate. The ESD protection circuit may further comprise a first terminal to connect the isolation region to a first electrical node, and a second terminal to connect the second doped region to a second electrical node. The first electrical node may have a higher voltage level than the second electrical node, and the gate and backgate may be coupled to the second terminal.
US08101999B2 SOI substrate and method for producing the same, solid-state image pickup device and method for producing the same, and image pickup apparatus
A SOI substrate includes a silicon substrate, a silicon oxide layer arranged on the silicon substrate, a silicon layer arranged on the silicon oxide layer, a gettering layer arranged in the silicon substrate, and a damaged layer formed of an impurity-doped region arranged in the silicon oxide layer.
US08101997B2 Semiconductor device with a charge carrier compensation structure in a semiconductor body and method for its production
A semiconductor device with a charge carrier compensation structure in a semiconductor body and to a method for its production. The semiconductor body includes drift zones of a first conduction type and charge compensation zones of a second conduction type complementing the first conduction type. The drift zones include a semiconductor material applied in epitaxial growth zones, wherein the epitaxial growth zones include an epitaxially grown semiconductor material which is non-doped to lightly doped. Towards the substrate, the epitaxial growth zones are provided with a first conduction type incorporated by ion implantation over the entire surface and with selectively introduced doping material zones of a second, complementary conduction type. Towards the front side, the epitaxial growth zones are provided with a second, complementary conduction type incorporated by ion implantation over the entire surface and with selectively introduced doping material zones of the first conduction type.
US08101995B2 Integrated MOSFET and Schottky device
A power semiconductor device that includes a trench power MOSFET with deep source field electrodes and an integrated Schottky diode.
US08101991B2 Semiconductor device with vertical current flow and low substrate resistance and manufacturing process thereof
A semiconductor device with vertical current flow includes a body having a substrate made of semiconductor material. At least one electrical contact on a first face of the body. A metallization structure is formed on a second face of the body, opposite to the first face. The metallization structure is provided with metal vias, which project from the second face within the substrate so as to form a high-conductivity path in parallel with portions of said substrate.
US08101990B2 Semiconductor device
A semiconductor device is provided, which includes a first insulating layer over a first substrate, a transistor over the first insulating layer, a second insulating layer over the transistor, a first conductive layer connected to a source region or a drain region of the transistor through an opening provided in the second insulating layer, a third insulating layer over the first conductive layer, and a second substrate over the third insulating layer. The transistor comprises a semiconductor layer, a second conductive layer, and a fourth insulating layer provided between the semiconductor layer and the second conductive layer. One or plural layers selected from the first insulating layer, the second insulating layer, the third insulating layer, and the fourth insulating layer have a step portion which is provided so as not to overlap with the transistor.
US08101989B2 Charge trapping devices with field distribution layer over tunneling barrier
A memory cell comprising: a semiconductor substrate with a surface with a source region and a drain region disposed below the surface of the substrate and separated by a channel region; a tunneling barrier dielectric structure with an effective oxide thickness of greater than 3 nanometers disposed above the channel region; a conductive layer disposed above the tunneling barrier dielectric structure and above the channel region; a charge trapping structure disposed above the conductive layer and above the channel region; a top dielectric structure disposed above the charge trapping structure and above the channel region; and a top conductive layer disposed above the top dielectric structure and above the channel region are described along with devices thereof and methods for manufacturing.
US08101988B2 Nonvolatile semiconductor memory device
A nonvolatile semiconductor memory device includes a semiconductor substrate that includes a trench, a charge storage layer that is formed inside of the trench, a first gate that is formed above a side surface and a bottom surface of the trench, a second gate that is formed beside the first gate, and that is formed above the charge storage layer, a first diffusion region that is formed on the semiconductor substrate inside of the trench, and a second diffusion region that is formed on the semiconductor substrate outside of the trench.
US08101987B2 Semiconductor device and method of fabricating the same
A semiconductor device is disclosed. The semiconductor device includes: a first electrode, disposed over a first region of a substrate; and a conductive layer, disposed over the substrate, including a second electrode disposed above the first electrode, wherein the second electrode comprises a mesh main part having a plurality of openings, and a plurality of extending parts, wherein the extending parts are connected to the mesh main part at periphery of the openings and extend toward a surface of the first electrode.
US08101982B2 Memory device which comprises a multi-layer capacitor
A memory device is provided. The memory device including memory cells having at least three stacked electrodes spaced apart pairwise by dielectric material so that the pairs of electrodes form respective capacitor layers. The capacitors are connected electrically in parallel to each other. The dielectric material is optionally ferroelectric material, in which case the capacitors are ferrocapacitors.
US08101977B2 Ballasted polycrystalline fuse
A polycrystalline fuse includes a first layer of polycrystalline material on a substrate and a second layer of a silicide material on the first layer. The first and second layers are shaped to form first and second terminal portions of a first width joined along a length of the fuse by a fuse portion of a second width narrower than the first width. First and second contacts are connected to the first and second terminal portions respectively. The silicide material being discontinuous in a terminal region of the second layer along the length of the fuse.
US08101976B2 Device selection circuitry constructed with nanotube ribbon technology
A memory system having electromechanical memory cells and decoders is disclosed. A decoder circuit selects at least one of the memory cells of an array of such cells. Each cell in the array is a crossbar junction at least one element of which is a nanotube or a nanotube ribbon. The decoder circuit is constructed of crossbar junctions at least one element of each junction being a nanotube or a nanotube ribbon.
US08101972B2 Nitride semiconductor device and method for fabricating the same
A nitride semiconductor device includes: first through third nitride semiconductor layers formed in sequence over a substrate. The second nitride semiconductor layer has a band gap energy larger than that of the first nitride semiconductor layer. The third nitride semiconductor layer has an opening. A p-type fourth nitride semiconductor layer is formed so that the opening is filled therewith. A gate electrode is formed on the fourth nitride semiconductor layer.
US08101971B2 Multicolor photodiode array and method of manufacturing
Novel structures of the photodetector having broad spectral ranges detection capability are provided. The photodetector offers high quantum efficiency>95% over wide spectral ranges, high frequency response>10 GHz (@3 dB). The photodiode array of N×N (or M×N) elements is also provided. The array also offers wide spectral detection ranges ultraviolet to 2500 nm with high quantum efficiency>95% and high frequency response of >10 GHz, cross-talk of <0.1%. In the array, each photodiode is independently addressable and is made either as top-illuminated or as bottom illuminated type detector. The photodiode and its array provided in this invention, could be used in multiple purpose applications such as telecommunication, imaging, and sensing applications including surveillance, satellite tracking, advanced lidar systems, etc. The advantages of this photodetectors are that they are uncooled and performance will not be degraded under wide range of temperature variation.
US08101969B2 Bi-directional transistor with by-pass path and method therefor
In one embodiment, a transistor is formed to have a first current flow path to selectively conduct current in both directions through the transistor and to have a second current flow path to selectively conduct current in one direction.
US08101964B2 Semiconductor light-emitting element and process for production thereof
The present invention provides a semiconductor light-emitting element comprising an electrode part excellent in ohmic contact and capable of emitting light from the whole surface. An electrode layer placed on the light-extraction side comprises a metal part and plural openings. The metal part is so continuous that any pair of point-positions in the part is continuously connected without breaks, and the metal part in 95% or more of the whole area continues linearly without breaks by the openings in a straight distance of not more than ⅓ of the wavelength of light emitted from an active layer. The average opening diameter is of 10 nm to ⅓ of the wavelength of emitted light. The electrode layer has a thickness of 10 nm to 200 nm, and is in good ohmic contact with a semiconductor layer.
US08101962B2 Carrying structure of semiconductor
A carrying structure of semiconductor includes a carrier made of a plastic material with a heat conduction region, each surface of the carrier has an interface layer formed on, and an electrically insulation circuit and a metal layer are defined on the interface layer. The insulation circuit is located on the surface of the heat conduction region and on an encircling annular region extended from two surfaces of the heat conduction region, and at the same time exposing parts of the carrier surface thereby splitting the metal layer on the interface layer into at least two electrodes. A thermal conductor formed in the heat conduction region has a LED chip adhered on it which has at least a contact point connected with the corresponding metal layer with a metal wiring so as to dissipate the heat generated by the chip rapidly with the thermal conductor.
US08101956B2 Light emitting device package and light unit having the same
Discussed is a semiconductor LED package. The semiconductor LED package includes a packet body having a cavity, a semiconductor light emitting device in the cavity of the package body; and a plurality of reflective frames, each of the reflective frames having a bottom frame in the cavity of the package body, and at least two sidewall frames extending from the bottom frame and inclined with respect to the bottom frame, wherein the plurality of reflective frames are electrically separated from each other.
US08101955B2 PLCC package with a reflector cup surrounded by an encapsulant
In an embodiment, the invention provides a PLCC package comprising first and second lead frames, a plastic structural body, a light source, an encapsulant, and an optical lens. The first lead frame comprises two tongues and a reflector cup. The first and second lead frames are attached to the plastic structural body. The light source is mounted and electrically connected at the bottom of the inside of the reflector cup. The light source is also electrically connected to the second lead frame by a wire bond. The reflector cup is surrounded on at least four sides by the encapsulant, the encapsulant having a domed portion that functions as the optical lens, the encapsulant being an integral single piece structure.
US08101954B2 Photo-semiconductor device and method of manufacturing the same
A photo-semiconductor device comprises a photoconductive semiconductor film provided with electrodes and formed on a second substrate, the semiconductor film being formed by epitaxial growth on a first semiconductor substrate different from the second substrate, the second substrate being also provided with electrodes, the electrodes of the second substrate and the electrodes of the photoconductive semiconductor film being held in contact with each other.
US08101949B2 Treatment of gate dielectric for making high performance metal oxide and metal oxynitride thin film transistors
Embodiments of the present invention generally include TFTs and methods for their manufacture. The gate dielectric layer in the TFT may affect the threshold voltage of the TFT. By treating the gate dielectric layer prior to depositing the active channel material, the threshold voltage may be improved. One method of treating the gate dielectric involves exposing the gate dielectric layer to N2O gas. Another method of treating the gate dielectric involves exposing the gate dielectric layer to N2O plasma. Silicon oxide, while not practical as a gate dielectric for silicon based TFTs, may also improve the threshold voltage when used in metal oxide TFTs. By treating the gate dielectric and/or using silicon oxide, the threshold voltage of TFTs may be improved.
US08101948B2 Switching element
In a switching element using, for the active layer, a carbon nanotube (CNT) dispersed film which can be manufactured at low temperatures, the interaction between the CNT and the surface of the gate insulating film is insufficient. For this reason, a problem of such a switching element is that the amount of CNT fixed in the channel region is insufficient, resulting in insufficient uniformity. In the switching element of the exemplary embodiment, a gate insulating film is formed of a nonconjugated polymer material containing, in the main chain, an aromatic group and a substituted or unsubstituted alkylene or alkyleneoxy group having 2 or more carbon atoms as repeating units. As a result, the interaction between the CNT and the surface of the gate insulating film is enhanced while maintaining the flexibility of the gate insulating film, and the amount of CNT fixed in the channel region can be increased. Thereby, a switching element having good and stable transistor characteristics can be obtained by a low-temperature, simple, and inexpensive process.
US08101943B2 Semiconductor device
It is an object of the present invention to provide a technique in which a high-performance and high reliable memory device and a semi-conductor device provided with the memory device are manufactured at low cost with high yield. The semiconductor device includes an organic compound layer including an insulator over a first conductive layer and a second conductive layer over the organic compound layer including an insulator. Further, the semiconductor device is manufactured by forming a first conductive layer, discharging a composition of an insulator and an organic compound over the first conductive layer to form an organic compound layer including an insulator, and forming a second conductive layer over the organic compound layer including an insulator.
US08101938B2 Method of forming a chalcogenide memory cell having an ultrasmall cross-sectional area and a chalcogenide memory cell produced by the method
A method of fabricating a chalcogenide memory cell is described. The cross-sectional area of a chalcogenide memory element within the cell is controlled by the thickness of a bottom electrode and the width of a word line. The method allows the formation of ultra small chalcogenide memory cells.
US08101934B2 Methods and apparatus for detecting a substrate notch or flat
In a first aspect, a first apparatus is provided. The first apparatus includes a through-beam sensor coupled to a scrubber and adapted to detect a notch or flat of a substrate in the scrubber during processing. The through-beam sensor has (1) an emitter facing a first major surface of a substrate in the scrubber and adapted to transmit a beam toward an edge of the first major surface; and (2) a receiver facing a second major surface of the substrate and adapted to receive the beam transmitted from the emitter when the edge of the substrate does not obstruct the beam. Numerous other aspects are provided.
US08101931B2 RF screen assembly for microwave powered UV lamps
An RF screen for microwave powered UV lamp systems is provided. The RF screen is formed of a single sheet of conductive material in which a mesh pattern has been formed. The screen includes a non-traditional mesh pattern including individual openings with 3 or more nodes. The RF screen is generally configured to optimize the balance between light transmission and RF energy leakage desired for the particular application. Generally, it is desired that the RF screen has an open area percentage greater than about 80% while limiting RF energy leakage from the microwave powered lamp system to acceptable levels.
US08101924B2 Object-positioning device for charged-particle beam system
An object-positioning device comprises a rod-like object holder inserted in the chamber of a charged-particle beam system for moving the object outside the chamber, a support for slideably supporting at least a part of the side surface of the object holder, thus making the rear end of the holder outside the chamber a free end, and a vibration-absorbing portion mounted on the rear end of the object holder. The vibration-absorbing portion has an operating range in which vibrational frequencies in a translational direction perpendicular to the longitudinal direction of the object holder are absorbed. The natural vibrational frequency of the object holder in the bending mode is included within the operating range of the vibration-absorbing portion.
US08101923B2 System and method for spatially-resolved chemical analysis using microplasma desorption and ionization of a sample
A method and system for desorbing and ionizing molecules from a sample for mass spectrometry using a microplasma device is disclosed. The system and method relies upon a microplasma device, or array of such devices, to partially ionize a gas to form a microplasma. The ionized gas can be a mixture of a noble gas, such as neon or argon, and hydrogen (H2). The ionized gas can form a effluent stream directed onto the surface of a sample to desorb molecules from the remainder of the sample. The desorbed molecules can be ionized by the effluent stream as they leave the surface of the sample. The ionization process can include: photoionization, penning ionization, chemical ionization (proton transfer), and electron impact ionization. The ionized particles from the sample can be directed to a mass spectrometer for analysis. This can produce spatially-resolved mass spectral data, and can be conducted concurrently with another imaging system, such as a microscope.
US08101907B2 Methods for quantitative lithological and mineralogical evaluation of subsurface formations
Methods, systems, apparatus and processes for determining the lithology as well as the mineralogy of subterranean formations surrounding a borehole are described. According to the methods and processes, well log data measurements from neutron spectroscopy applications and associated tool response parameters are solved using an artificial intelligence system, such as an expert system, which in turn generates an appropriate discriminator and/or compositional model that estimates both general and specific lithology as well as the mineralogy constraints of the subterranean formation being analyzed. The methods exhibit good elemental correlation between conventional methods of lithology and mineralogy determination, and can provide numerous output data, including grain density and porosity data within zones of the formation.
US08101906B2 Method and apparatus for calibrating optical path degradation useful for decoupled plasma nitridation chambers
Methods for matching semiconductor processing chambers using a calibrated spectrometer are disclosed. In one embodiment, plasma attributes are measured for a process in a reference chamber and a process in an aged chamber. Using a calibrated light source, an optical path equivalent to an optical path in a reference chamber and an optical path in an aged chamber can be compared by determining a correction factor. The correction factor is applied to adjust a measured intensity of plasma radiation through the optical path in the aged chamber. Comparing a measured intensity of plasma radiation in the reference chamber and the adjusted measured intensity in the aged chamber provide an indication of changed chamber conditions. A magnitude of change between the two intensities can be used to adjust the process parameters to yield a processed substrate from the aged chamber which matches that of the reference chamber.
US08101903B2 Method, apparatus and system providing holographic layer as micro-lens and color filter array in an imager
A method, apparatus, and system that provides a holographic layer as a micro-lens array and/or a color filter array in an imager. The method of writing the holographic layer results in overlapping areas in the hologram for corresponding adjacent pixels in the imager which increases collection of light at the pixels, thereby increasing quantum efficiency.
US08101901B2 Method and apparatus for acquiring physical information, method for manufacturing semiconductor device including array of a plurality of unit components for detecting physical quantity distribution, light-receiving device and manufacturing method therefor, and solid-state imaging device and manufacturing method therefor
Method and apparatus for acquiring physical information, method for manufacturing semiconductor device including array of a plurality of unit components for detecting physical quantity distribution, light-receiving device and manufacturing method therefor, and solid-state imaging device and manufacturing method therefore are provided. The method for acquiring physical information uses a device for detecting a physical distribution, the device including a detecting part for detecting an electromagnetic wave and a unit signal generating part for generating a corresponding unit signal on the basis of the quantity of the detected electromagnetic wave. The detecting part includes a stacked member having a structure in which a plurality of layers having different refractive indexes between the adjacent ones and each having a predetermined thickness is stacked, the stacked member being provided on the incident surface side to which the electromagnetic wave is incident and having the characteristic that a predetermined wavelength region component of the electromagnetic wave is reflected, and the remainder is transmitted.
US08101899B2 Image pickup apparatus
An apparatus includes pixels each having a transistor that transfers a charge of a photoelectric conversion unit, an amplification unit that receives the transferred charge, a scanning unit that supplies, to the transistor, a conductive pulse, a non-conductive pulse, and an intermediate-level pulse having a peak value between the conductive pulse and the non-conductive pulse, a generating unit that generates an image signal using a signal based on a charge transferred in response to the conductive and intermediate-level pulses, and a control unit that changes at least one of a pulse width of the intermediate-level pulse and the peak value in accordance with information on the detected temperature. The conductive and intermediate-level pulses are supplied to the transistor during a light shielding period of the photoelectric conversion unit.
US08101897B2 Laboratory apparatus for simultaneously carrying out reactions in a plurality of samples
The invention relates to a laboratory apparatus for simultaneously carrying out reactions in a plurality of samples which are arranged in an array. The apparatus includes an illumination device, which emits illumination light onto the samples, a detection device, which generates a signal dependent on the light intensity of the light coming from the samples and which forwards the signal to an evaluation device, and a monitoring device for checking the functioning of the illumination device. The illumination device has a plurality of light-emitting diodes assigned in each case to one of the samples, and the monitoring device has electrical devices which can be used to perform an electrical functional check of the light-emitting diodes. The monitoring device is adapted to generate a signal when a functional disturbance of a light-emitting diode is ascertained.
US08101894B2 Cooking device with deodorization
A cooking device includes an inner case, a cooking chamber within the inner case and an odor removal unit configured to generate a plasma discharge for removing odor-producing materials from the cooking chamber.
US08101893B2 Vestibule apparatus
A vestibule for use with a microwave oven having a conveyor mechanism passing there-through is designed to prevent microwave radiation from escaping to the surrounding atmosphere. The vestibule includes a choke region and a paddlewheel region with a trap region located directly there-between. The choke region includes a series of quarter wave choke networks or devices and the trap region includes a body having quarter wave chokes with microwave absorbent materials disposed therein which absorb microwave radiation that has passed through the choke region. The paddlewheel region includes at least two pairs of paddlewheels that are synchronized with the conveyor mechanism and each other to permit individual products to enter an open end of the vestibule while preventing microwave radiation from escaping therefrom. The paddlewheels are synchronized such that while one pair of paddlewheels is in an open state, the other pair is in the closed state.
US08101885B2 Laser processing method and laser processing apparatus
The present invention relates to a method and apparatus having a structure that enables laser processing of an object even when the object has a surface formed with irregularities. The laser processing method irradiates objects, each having a cylindrical form extending in a first direction, with laser light. Here, the objects are arranged on a first plane along a second direction orthogonal to the first direction. The arranged objects are irradiated with first and second laser light beams in irradiation directions different from each other to the first plane. At least during when the first and second irradiation light beams are respectively emitted, irradiation positions of the first and second laser light beams to the first plane are relatively moved.
US08101884B2 Method for production of a pressure-sensitive adhesive sheet
A pressure sensitive adhesive sheet 1 includes a base material 11 and a pressure sensitive adhesive layer 12. A plurality of through holes 2 pass through one face of the pressure sensitive adhesive sheet 1 to the other face. The hole diameter of the through holes 2 is 0.1 to 300 μm and the hole density is 30 to 50,000/100 cm2. It is preferable to form the through holes 2 using a laser beam machining. In the pressure sensitive adhesive sheet 1, an air trapping or a blister can be prevented or removed without disfiguring the pressure sensitive adhesive sheet and while maintaining sufficient adhesive strength.
US08101882B2 Plasma torch electrode with improved insert configurations
An improved electrode for use in a plasma arc torch. The electrode includes an electrode body, a bore defined by and disposed in the electrode body, and an insert disposed in the bore. The insert and/or the bore of the electrode are configured to improve retention of the insert in the electrode, thereby extending electrode life. The invention also includes a method for forming the electrode. The method includes a step of positioning an insert into a bore of an electrode such that an exterior gap is established that is greater than a second gap.
US08101880B2 Operator control panel for a domestic appliance
An operator control panel for a domestic appliance includes a panel body having an operator control face facing a user and a rear face facing away from the operator control face. A sensor element of an electrically conductive material forms a capacitive sensor area together with the panel body. A conversion electronics system converts capacitance values generated in the sensor area into digital signals. The conversion electronics system is electrically conductively connected to the sensor element and is disposed on the rear face of the panel body. The sensor element and the conversion electronics system are firmly connected to the panel body and are two components which are mechanically decoupled from a control electronics system of the domestic appliance.
US08101878B2 GU24 3-way dimmer knob-type switch lampholder
A GU24 3-way dimmer knob-type switch lamp holder is disclosed, where the body of the lamp holder is provided with three contact plates at the two sides of its interior and on its bottom. And an insulating rotor and a rotor conducting plate therein is driven by a knob. The rotor conducting plate is shaped into four portions along its rim, where three of them come with a shaped contact plate, while the fourth is void. The insulating rotor and the rotor conducting plate are driven to rotate by turning the knob, which enables three contact plates in the body and three contact plates of the rotor conducting plate to form no conduction or different conduction modes that enable various levels of illumination: dim, moderate and high brightness after power ON and feature power OFF as well.
US08101876B2 Electro-mechanical pulse generator
An electromechanical pulse generator and a method of generating electrical pulses are disclosed. The electromechanical pulse generator comprises very few parts and includes an effective mechanism to prevent contact rebound. An upper, user-actuable and rotatable part has a surface with a plurality of projections. A lower part has an electrical conductor with a displaceable resilient contact portion biased against the projections and two electrical contacts positioned, in the plane of rotation, on either side of the displaceable contact portion.
US08101873B2 Protective structure for a circuit board and method for fabricating the same
In a protective structure for a circuit board (1) that includes a casing (3) for receiving the circuit board, the casing is provided with a recess (11) for receiving a large component part protruding from the circuit board therein, and potting material (6) is filled in a space defined between the large component part and a surrounding wall of the recess. Typically, the potting material is filled in a gap between the large component part and the surrounding wall of the recess without substantially extending out of the recess. Because the large component part is not only supported by the circuit board but also by the casing via the cured potting material, the stress acting on a connection part that connects the large component part to the circuit board is minimized, and this enhances the mechanical integrity of the circuit board assembly. Because the use of the potting material is limited to the recess, the required amount of the potting material can be minimized, and this means a lower material cost and a reduced weight. Reducing the amount of the potting material means a shorter period of time required for curing it, and this improves the production efficiency of the circuit board assembly. If the protection of the component parts from intrusion of moisture is desired, protective coating may be additionally applied to the circuit board.
US08101870B2 Method for manufacturing printed circuit board, printed circuit board, and electronic apparatus
A method for manufacturing a printed circuit board. The method includes: preparing a printed wiring board, the printed wiring board comprising through holes and a plurality of electrode pads; coating surfaces of the plurality of electrode pads and surfaces of the through holes on an one side of the printed wiring board with a bonding material; mounting a semiconductor package on the printed wiring board such that a plurality of bumps on a surface of the semiconductor package corresponds to the plurality of electrode pads; bonding the bumps to the electrode pads by heating the printed wiring board on which the semiconductor package is mounted; and filling a space between the semiconductor package and the printed wiring board with a filler material.
US08101868B2 Multilayered printed circuit board and method for manufacturing the same
A multilayered printed circuit board or a substrate for mounting a semiconductor device includes a semiconductor device, a first resin insulating layer accommodating the semiconductor device, a second resin insulating layer provided on the first resin insulating layer, a conductor circuit provided on the second resin insulating layer, and via holes for electrically connecting the semiconductor device to the conductor circuit, wherein the semiconductor device is accommodated in a recess provided in the first resin insulating layer, and a metal layer for placing the semiconductor device is provided on the bottom face of the recess. A multilayered printed circuit board in which the installed semiconductor device establishes electrical connection through the via holes is provided.
US08101867B2 Electroless Ni-P plating method and substrate for electronic component
An electroless Ni—P plating method according to the present invention includes the steps of: providing a substrate including an insulating substrate and a copper alloy layer that has a predetermined pattern including a plurality of island portions that are isolated from each other; providing a plating solution to carry out electroless Ni—P plating; providing a solid piece including Ni, Ni—P, Co or Co—Ni on at least the surface thereof; and bringing the solid piece into contact with the surface of at least two of the island portions that are both in contact with the plating solution, thereby selectively forming an electroless Ni—P plated coating on the surface of the island portions. Thus, the present invention provides a Ni—P plating method that can subject the copper pattern on the insulating substrate to high-precision selective Ni—P plating on an industrial basis.
US08101866B2 Packaging substrate with conductive structure
A packaging substrate with conductive structure is provided, including a substrate body having at least one conductive pad on a surface thereof, a stress buffer metal layer disposed on the conductive pad, a solder resist layer disposed on the substrate body and having at least one opening therein for correspondingly exposing a portion of top surface of the stress buffer metal layer, a metal post disposed on a central portion of the surface of the stress buffer metal layer, and a solder bump covering the surfaces of the metal post. Therefore, a highly reliable conductive structure is provided, by using the stress buffer metal layer to release thermal stresses, and using the metal post and the solder bump to increase the height of the conductive structure.
US08101862B2 Self-sealing electrical cable using rubber resins
An electrical cable and a method for manufacturing the electrical cable are provided in which a plurality of insulated conductors have an inner protective layer extruded thereabout. A plurality of longitudinally extending ribs or fins or exterior ribbed or finned surfaces are formed outward of the inner protective layer between which exist a plurality of voids. An outer insulation layer can be formed in the same operation as the fins or ribbed surface and the inner layer or in a subsequent operation. A self-sealing elastomeric material is applied to the conductor surface or is present between the fins and between the inner protective layer and the outer insulation layer.
US08101861B1 Electrical device cover
A cover for electrical devices is disclosed. Particular implementations include an electrical device cover configured to mount over an electrical device includes a lid having a flexible membrane. The lid is coupled by a hinge to a base and the cover includes a cord port in an edge of a surface of the cover. The lid is configured to expand through the flexible membrane to an expanded position to accommodate an electrical connector coupled with the electrical device. The lid may also be configured to reduce in depth as the lid retracts from the expanded position to a refracted position through the flexible membrane.
US08101857B2 Organic devices, organic electroluminescent devices and organic solar cells
An organic device, including an organic compound having charge-transporting ability (i.e., transporting holes and/or electrons) and/or including organic light emissive molecules capable of emitting at least one of fluorescent light or phosphorescent light, has a charge transfer complex-contained layer including a charge transfer complex formed upon contact of an organic hole-transporting compound and molybdenum trioxide via a manner of lamination or mixing thereof, so that the organic hole-transporting compound is in a state of radical cation (i.e., positively charged species) in the charge transfer complex-contained layer.
US08101853B2 Solar cell electrode
A p-type electrode on p+ layer of solar cell comprising, prior to firing; (a) Electrically conductive particles comprising silver particle having a particle size of 0.1 to 10 microns and added particle composed of silver particle coated with a metal selected from the group consisting of Mo, Tc, Ru, Rh, Pd, W, Re, Os, Ir and Pt, (b) Glass frit, and (c) A resin binder, wherein the electrode is made from a fired conductive paste which is comprised of 40 to 90 wt % of the silver particle and 0.01 to 10 wt % of the added particle based on the weight of the paste.
US08101852B2 Single-sided contact solar cell with plated- through holes and method for its production
In an embodiment of the present invention, a single-sided contact solar cell includes an absorber layer with plated-through holes; an emitter layer disposed on a first side of the absorber layer, the emitter layer including one or more semiconductor materials having different dopants; a field passivation layer disposed on a second side of the absorber layer; a contact grid covered on a top surface thereof with an insulation layer and electrically connected to a first end of the plated-through holes; and a contact layer. The contact grid and contact layer are disposed together on one side of the absorber layer and insulated with respect to each other and electrically contacted from outside of the solar cell. The contact grid is disposed between the absorber layer and the emitter layer or the field passivation layer, and the contact layer is disposed on the emitter layer or on the field passivation layer so that both the contact grid and contact layer are disposed on a top surface of the solar cell. The emitter layer or the field passivation layer is electrically connected to a second end of the plated-through holes. Where the second end of the plated-through holes is electrically connected to the emitter layer, the absorber layer and the contact grid are electrically insulated from each other.
US08101849B2 Tilt assembly for tracking solar collector assembly
A tilt assembly is used with a solar collector assembly of the type comprising a frame, supporting a solar collector, for movement about a tilt axis by pivoting a drive element between first and second orientations. The tilt assembly comprises a drive element coupler connected to the drive element and a driver, the driver comprising a drive frame, a drive arm and a drive arm driver. The drive arm is mounted to the drive frame for pivotal movement about a drive arm axis. Movement on the drive arm mimics movement of the drive element. Drive element couplers can extend in opposite directions from the outer portion of the drive arm, whereby the assembly can be used between adjacent solar collector assemblies in a row of solar collector assemblies.
US08101848B2 Solar photovoltaic output for cloudy conditions with a solar tracking system
An array of solar powered photovoltaic modules is optimally oriented and operated to provide more electrical energy for uses such as powering an electrolyzer system for hydrogen production. The array is positioned with its light receiving surface at an optimal angle, preferably a continually changing angle determined by two-axis solar tracking, when continually measured solar irradiance indicates suitable sunlight, and at a horizontal position when measured solar irradiance indicates excessive atmospheric cloudiness.
US08101844B2 Automatic analysis and performance of music
Methods for automatically analyzing and/or performing music are described. One embodiment concerns a method for assigning chords to a musical score indicative of a sequence of time segments, each time segment comprising at least one note, the method comprising assigning a chord to each time segment responsive to consonance/dissonance relationships between the assigned chord and the notes of at least two of the time segments. Optionally, consonance/dissonance relationships include existence of a dissonant between a chord assigned to a time segment and a note of the time segment and existence of resolution to said dissonant.
US08101841B2 One-handed musical triangle
A triangle musical instrument that may be played using a single hand. The triangle is formed such that a percussionist is able to grasp the triangle in one hand and shake it in a back-and-forth motion to produce the familiar triangle musical instrument sound. Openings formed in the sides of the instrument allow the percussionist to mute the sounds.
US08101838B2 Water-soluble nanoparticles with controlled aggregate sizes
A method of forming dispersed water-soluble quantum dots and tuning water-soluble quantum dot aggregate size by providing a plurality of water-soluble quantum dots in a dispersion, the plurality of water-soluble quantum dots are modified with an amphiphilic polymer, and by adding an amount of the amphiphilic polymer to the dispersion such that the ratio of the amphiphilic polymer units to quantum dots is maintained higher to obtain dispersions of smaller quantum dot aggregates and kept lower to obtain dispersions of larger quantum dot aggregates.
US08101833B2 Soybean cultivar S080203
A soybean cultivar designated S080203 is disclosed. The invention relates to the seeds of soybean cultivar S080203, to the plants of soybean S080203, to plant parts of soybean cultivar S080203, and to methods for producing a soybean plant produced by crossing soybean cultivar S080203 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080203, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080203, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080203 with another soybean cultivar.
US08101830B1 Soybean variety RJS37003
According to the invention, there is provided a novel soybean variety designated RJS37003. This invention thus relates to the seeds of soybean variety RJS37003, to the plants of soybean RJS37003 to plant parts of soybean variety RJS37003 and to methods for producing a soybean plant produced by crossing plants of the soybean variety RJS37003 with another soybean plant, using RJS37003 as either the male or the female parent.
US08101826B2 Expression of Cry3B insecticidal protein in plants
The present invention discloses methods and compositions comprising a group of novel expression cassettes which provide significantly improved levels of accumulation of Coleopteran inhibitory Cry3B and Cry3B variant amino acid sequences when these are expressed in plants. The preferred embodiments of the invention provide at least up to ten fold higher levels of insect controlling protein relative to the highest levels obtained using prior compositions. In particular, transgenic maize expressing higher levels of a protein designed to exhibit increased toxicity toward Coleopteran pests deliver superior levels of insect protection and are less likely to sponsor development of populations of target insects that are resistant to the insecticidally active protein.
US08101822B2 Method for preventing mutation of pathogens exposed to transgenic plants
A method for preventing mutation of pathogens or pest insects due to exposure to genetically-modified or transgenic plants, comprising: (a) introducing separately a plurality of resistance genes conferring pest and disease resistance to a given recipient plant variety or combinations of the varieties to form a plurality of transgenic plant lines each harboring different resistance genes; (b) multiplying the transgenic plant lines separately to obtain separate transgenic plant lines; and (c) mixing seeds of the separate transgenic plant lines in a specific weight ratio to form a final transgenic product. Additionally, small number of seeds of the non-transformed plants is incorporated in the transgenic plant lines according to demand. As a result, an excessive selective pressure for targeted insects and pathogens are alleviated considerably, the possibility of auto mutation of the targeted insects and pathogens will be reduced, and the application duration of transgenic crop varieties will be prolonged effectively.
US08101819B2 DGAT genes for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
Transgenic oilseeds having increased total fatty acid content of at least 10% and altered fatty acid profiles when compared to the total fatty acid content of null segregant oilseeds are described. Novel DGAT genes are used to achieve the increase in seed storage lipids.
US08101816B2 RGMc modified transgenic animals
The invention provides a new reproducible transgenic mouse model for the study of iron accumulation in the body. In particular, the invention concerns the study of iron overload in an RGMc knockout mouse model and its use in drug discovery and research.
US08101807B2 Methods for converting glycerol to propanol
A hydrogenolysis method for converting glycerol into propylene glycol by directing a glycerol containing feed having a pH of about 10 or more to a reaction section including at least one glycerol conversion catalyst and operating at glycerol conversions conditions to form a reaction product including propylene glycol.
US08101805B2 Low pressure one-step gas-phase process for production of methyl isobutyl ketone
A low-pressure one-step gas-phase process for the production and recovery of methyl isobutyl ketone (MIBK) is disclosed. One-step gas-phase synthesis of MIBK from acetone and hydrogen over nano-Pd/nano-ZnCr2O4 catalyst at atmospheric pressure is used as an example. The said process is designed to recover the additional heat associated with the reactor effluent via heating acetone feed and recycle (mixed acetone) before entering the reactor. A compressor is introduced to the gas-phase process to increase slightly the reactor effluent pressure before this effluent is cooled and fed to a flash drum. The compressed reactor effluent is used to preheat hydrogen feed and recycle (mixed hydrogen) before entering the reactor. The separation scheme of low-pressure one-step gas-phase process comprises of several distillation columns used for MIBK separation and purification.
US08101800B2 5,6-dihydro-1H-pyridin-2-one compounds
The invention is directed to a 5,6-dihydro-1H-pyridin-2-one compound selected from:
US08101798B2 Manufacture of substantially pure monochloroacetic acid
A process for the manufacture of substantially pure monochloroacetic acid from a liquid chloroacetic acid mixture comprising monochloroacetic acid and dichloroacetic acid, in particular in an amount of 2 to 40 percent by weight, wherein said mixture, further mixed with a suspended hydrogenation catalyst, is mixed with hydrogen gas and the resulting mixture is brought to reaction in a reactor, which is characterized in that the reactor is a loop reactor comprising a gas and liquid recirculation system coupled via an ejector mixing nozzle, in which reactor the gas and liquid are circulated in co-current flow, and the mixing intensity introduced to the liquid phase is at least 50 W/l of liquid phase.
US08101795B2 Process for preparing high purity corosolic acid and high purity ursolic acid
According to the present invention, there is provided a process for preparing corosolic acid comprising the steps of (1) dissolving crude extract of Japanese loquat leaves in alkali and aqueous alcohol and (2) applying the solution to a nonpolar adsorption resin to obtain corosolic acid.
US08101794B2 Crystalline forms of a 3-carboxypropyl-aminotetralin compound
The invention provides crystalline solid forms of (S)-4-((2S,3S)-7-carbamoyl-1,1 -diethyl-3-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)-2-cyclohexylmethyl-butyric acid. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline solid forms.
US08101788B2 Silicon precursors and method for low temperature CVD of silicon-containing films
Novel silicon precursors for low temperature deposition of silicon films are described herein. The disclosed precursors possess low vaporization temperatures, preferably less than about 500° C. In addition, embodiments of the silicon precursors incorporate a —Si—Y—Si— bond, where Y may comprise an amino group, a substituted or unsubstituted hydrocarbyl group, or oxygen. In an embodiment a silicon precursor has the formula: where Y is a hydrocarbyl group, a substituted hydrocarbyl group, oxygen, or an amino group; R1, R2, R3, and R4 are each independently a hydrogen group, a hydrocarbyl group, a substituted hydrocarbyl group, a heterohydrocarbyl group, wherein R1, R2, R3, and R4 may be the same or different from one another; X1, X2, X3, and X4 are each independently, a hydrogen group, a hydrocarbyl group, a substituted hydrocarbyl group, or a hydrazino group, wherein X1, X2, X3, and X4 may be the same or different from one another.
US08101785B2 Method for producing fatty acid alkanol amides
The invention relates to a method for producing fatty acid alkanol amides by reacting at least one amine that contains at least one primary or secondary amino group and at least one hydroxyl group with at least one fatty acid to form an ammonium salt, said ammonium salt being subsequently converted into the alkanol amide by means of microwave radiation.
US08101784B2 Process for removing volatile components from a substance mixture and apparatus for performing this process
A process and an apparatus separate a volatile component from a substance mixture (raw product). The substance mixture is heated, the volatile component is at least partly evaporated and then the vapor formed is condensed. To improve the separating action, the condensate, in the region of the point of condensation, is contacted with a liquid in which the condensate dissolves.
US08101772B2 Fungicidal active substance combinations containing trifloxystrobin
The present invention relates to novel active compound combinations comprising a known oxime ether derivative (trifloxystrobin) and imidacloprid, which combinations are highly suitable for controlling phytopathogenic fungi and insects.
US08101770B2 Pyridones useful as inhibitors of kinases
The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing the compounds of the invention and intermediate compounds useful in these processes.
US08101766B2 Crystalline form of a biphenyl compound
The invention provides a crystalline 1,2-ethanedisulfonic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-5-methoxyphenylcarbamoyl)ethyl]piperidin-4-yl ester or a solvate thereof. This invention also provides pharmaceutical compositions comprising such a salt or prepared using such a salt; processes and intermediates for preparing such a salt; and methods of using such a salt to treat a pulmonary disorder.
US08101765B2 Process for preparing acyclic HCV protease inhibitors
Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: The disclosed processes use SNAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety of the following formula: and halogenated or sulfonated bromoquinoline compounds.
US08101762B2 Nitrogen-containing organic compounds usable as catalytic composition precursors
The present invention describes novel nitrogen-containing organic compounds obtained by reacting a compound X of substituted pyridine type comprising at least one ketone function with a compound Y belonging to the aminoquinoleine family and derivatives thereof. Said organic compounds can be used as precursors in a catalytic composition.
US08101761B2 (E)-N-{3-[1-(8-fluoro-11H-10-OXA-1-AZA-dibenzo [A,D] cyclohepten-5ylidene)-propyl]-phenyl}-methanesulfonamide as glucocorticoid receptor modulator for the treatment of rheumatoid arthritis
The present invention provides Compound (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with one or more pharmaceutically acceptable carriers, excipients, or diluents; and discloses methods for the treatment of inflammatory and immune disorders comprising administering to a patient in need thereof an effective amount of Compound (I) or a pharmaceutically acceptable salt thereof.
US08101759B2 Acenaphthopyridine derivative, material of light-emitting element, light-emitting element, light-emitting device, and electronic appliance
It is an object to provide a new compound which is suitable for a material of an electron-transporting layer of a light-emitting element. In particular, it is an object to provide a compound which can be used for forming a light-emitting element capable of emitting light at a low drive voltage. An acenaphthopyridine derivative represented by the following general formula (G1) is provided. In the formula, Het represents a pyridyl group or a quinolyl group.
US08101756B2 Process for the preparation of quaternary N-alkyl morphin or morphinan alkaloid derivatives
The present invention relates to a process for the preparation of quaternary N-alkyl morphin or morphinan alkaloid derivatives. This is achieved by using a nucleophilic nitrogen, phosphor or sulfur containing base in the reaction mixture.
US08101753B2 Production method of pyrimidine compounds
4-amino-6-alkynyloxypyrimidine compounds shown by the formula (V) which has a controlling activity against pests can be produced by the method which comprises the first step which produces a 4-fluoro-6-alkynyloxypyrimidine compound shown by the formula (I) by making a 4,6-difluoropyrimidine compound shown by the formula (II) react with an alcohol compound shown by the formula (III) H—OR2  (III) in the presence of a tertiary amine; and the second step which produces the 4-amino-6-alkynyloxypyrimidine compound shown by the formula (V) by making the 4-fluoro-6-alkynyloxypyrimidine compound shown by the formula (I) react with an amine compound shown by the formula (IV)
US08101747B2 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
Process for the synthesis of ivabradine of formula (I): and addition salts thereof with a pharmaceutically acceptable acid.
US08101741B2 Modified siRNA molecules and uses thereof
The present invention provides chemically modified siRNA molecules and methods of using such siRNA molecules to silence target gene expression. Advantageously, the modified siRNA of the present invention is less immunostimulatory than its corresponding unmodified siRNA sequence and retains RNAi activity against the target sequence. The present invention also provides nucleic acid-lipid particles comprising a modified siRNA, a cationic lipid, and a non-cationic lipid, which can further comprise a conjugated lipid that inhibits aggregation of particles. The present invention further provides methods of silencing gene expression by administering a modified siRNA to a mammalian subject. Methods for identifying and/or modifying an siRNA having immunostimulatory properties are also provided.
US08101740B2 Positron emission tomography probes for imaging immune activation and selected cancers
Compounds for use as PET probes and methods for synthesizing and using these, comprising [18F]D-FAC and other cytosine and adenosine analogs.
US08101733B1 Methods of evaluating mixtures of polysaccharides
Methods for analyzing mixtures of polysaccharides, for example heparin or a LMWH, using reduce end labeling are described. In general, the mixture of polysaccharides includes polysaccharides having a desired structural moiety. In some instances, one or more polysaccharides in the mixture are chemically modified prior to analysis.
US08101732B2 Methods of producing validamycin A analogs and uses thereof
This disclosure relates to validamycin A biosynthesis and in particular, to methods of producing validamycin A analogs and uses thereof. In a particular example, a method for making a validamycin A analog includes transforming a host cell with one or more recombinant DNA vectors to produce a valN-inactivated mutant; and culturing the valN-inactivated mutant in a culture medium to produce a validamycin A analog, such as 1,1′-bis-valienamine and validienamycin, and their conversion to valienamine. The present disclosure further relates to compositions including such compounds as well as methods of using the compositions, such as for antifungal agents.
US08101730B2 Method for synthesizing rare-earth oxo isopropoxide
Provided is a method for synthesizing a rare-earth oxo isopropoxide safely with a high yield, using a rare-earth metal, which is more inexpensive than anhydrous rare-earth chlorides, as a raw material.In a solvent containing 90% or more by weight of isopropyl alcohol, a rare-earth metal and isopropyl alcohol are caused to react with each other in the presence of a mercury compound catalyst, a solvent is added thereto or the solvent is partially replaced, and then in a solvent containing 25% or more by weight of an aromatic hydrocarbon solvent having 6 to 10 carbon atoms or a saturated hydrocarbon solvent having 5 to 12 carbon atoms, water is added to conduct partial hydrolysis reaction, thereby synthesizing a rare-earth oxoisopropoxide.
US08101728B2 TAB molecules
The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
US08101726B2 Ligands binding the complex of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) that inhibit downstream uPAR interactions: identification and use in diagnosis or therapy
Antibodies or other ligands specific for the binary uPA-uPAR complexes, for ternary complexes comprising uPA-uPAR and for complexes of uPAR and proteins other than uPA such as integrins inhibit the interaction of uPA and uPAR with additional molecules with which the complexed interact. Such antibodies or other ligands are used in diagnostic and therapeutic methods, particularly against cancer.
US08101721B2 Antibodies blocking fibroblast growth factor receptor activation and methods of use thereof
The present invention is related to antibodies with binding affinity to fibroblast growth factor receptor 2 (FGFR2) optionally with binding affinity to other FGF receptors, which block both ligand-dependent and constitutive ligand independent receptor activation. Specifically, the present invention relates to antibodies with high affinity to more than one FGF receptor subtype, and fragments thereof, useful in treating disorders including cell proliferative diseases.
US08101710B2 Membrane separation process for removing residuals from polyamine-epihalohydrin resins
This invention relates to a process for preparing polyamine-epihalohydrin resins having reduced levels of residuals. The process comprises (a) charging a membrane separation apparatus with an aqueous composition comprising at least one polyamine-epihalohydrin resin, and (b) separating the aqueous composition into a permeate and a retentate by passing the aqueous composition through the membrane of the membrane separation apparatus. The retentate comprises at least one polyamine-epihalohydrin resin having lower levels of residuals on an equal active component basis than the aqueous composition of (a). The permeate comprises residuals removed from the aqueous composition of (a) and less than 5% by weight of the active component of said at least one polyamine-epihalohydrin resin. The polyamine-epihalohydrin resins having reduced levels of residuals can be used to make wet strength agents, dry strength agents, creping adhesives for paper products, curing agents for wood product adhesives, and other products.
US08101707B2 Process for the direct manufacture of polyglycerol polyricinoleate
A process for manufacturing polymers of glycerin and hydroxyl fatty acids, for example, polyglycerol polyricinoleates, which mix a polyglycerol with a hydroxyl fatty acid directly to form a reaction mixture, and then heat the reaction mixture to a temperature sufficient to cause it to polymerize through an esterification mechanism until the reaction mixture reaches a desired acid value.
US08101702B2 Silicone-containing composition
A silicone-containing composition comprises the reaction product of a first component and an excess of an isocyanate component relative to the first component to form an isocyanated intermediary. The first component is selected from one of a polysiloxane and a silicone resin. The first component includes a carbon-bonded functional group selected from one of a hydroxyl group and an amine group. The isocyanate component is reactive with the carbon-bonded functional group of the first component. The isocyanated intermediary includes a plurality of isocyanate functional groups. The silicone-containing composition comprises the further reaction product of a second component, which is selected from the other of the polysiloxane and the silicone resin. The second component includes a plurality of carbon-bonded functional groups reactive with the isocyanate functional groups of the isocyanated intermediary for preparing the silicone-containing composition.
US08101701B2 Fumaric acid derivatives and ophthalmic lenses using the same
Fumaric acid derivatives and ophthalmic lenses using them are disclosed. More specifically, a fumaric acid derivative having a hydrophilic group and a silicon-containing alkyl group within a molecule, and contact lenses or intraocular lenses using the same are disclosed. The fumaric acid derivatives of the present invention provide, on one hand, superior oxygen permeability by having a silicon-containing alkyl group within the molecular structure, and on the other hand, improved compatibility with other hydrophilic monomers by having a hydrophilic group within the same molecule. When ophthalmic lenses obtained by polymerizing monomer compositions containing the fumaric acid derivative are constructed as, for example, water content lenses, lenses with high oxygen permeability independent from the water content may be obtained, wherein the fumaric acid derivatives is superior in compatibility with the hydrophilic monomer used in combination and allows the combination in various mixing ratios.
US08101698B2 Surface active prepolymers with both fluorine-containing groups and hydrophilic groups
Provided are surface modified contact lenses formed from one or more fumaric-or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers.
US08101696B2 Polyolefin solution polymerization process and polymer
A catalyst composition comprising a zirconium complex of a polyvalent aryloxyether and a polymerization processes employing the same, especially a continuous, solution polymerization of ethylene and one or more C3-30 olefins or diolefins to prepare interpolymers having improved processing properties, are disclosed.
US08101695B2 Propylene based terpolymers
A propylene-based terpolymer comprising: a) from 10.0% by mol to 79.0% by mol of propylene derived units; b) from 89.5% by mol to 20.5% by mol of 1-butene derived units; and c) from 0.5% by mol to 15% by mol of derived units of alpha olefin of formula CH2═CHZ wherein Z is a C4-C20 alkyl radical.
US08101693B2 Multi reactor process
This invention relates to the polymerization of ethylene polymers using a continuously stirred tank reactor (CSTR) that is connected in series to a tubular reactor. The tubular reactor receives a polymer solution from the CSTR. Further polymerization in the tubular reactor improves production efficiencies, particularly with respect to lowering the amount of energy required to recover the polymer and residual comonomer from the solution. The use of tempered i.e. (heated) ethylene in the tubular reactor has been discovered to mitigate gel problems and lower/reduce levels of hexane extractables.
US08101689B2 Shape memory epoxy copolymer
The shape memory polymers disclosed are a reaction product of at least one reagent containing two active amino-hydrogen or two active phenolic-hydrogen with at least one multifunctional cross linking reagent which contains at least three or more active amino- or phenolic-hydrogen or is a reagent containing at least three glycidyl ether moieties which is then further mixed with at least one diglycidyl ether reagent whereupon the resulting mixture is cured and has a glass transition temperature higher than 00 C. This reaction creates crosslinking between the monomers and polymers such that during polymerization they form a crosslinked thermoset network.
US08101687B2 Multimodal polyethylene material
The present invention relates to a polyethylene resin having a multimodal molecular weight distribution, said resin being further characterized in that it has a density in the range of from about 0.925 g/ccm to about 0.950 g/ccm, a melt index (I2) In the range of from about 0.05 g/10 min to about 5 g/10 min, and in that it comprises at least one high molecular weight (HMW) ethylene interpolymer and at least a low molecular weight (LMW) ethylene polymer, and a composition comprising such resin. Also provided is a shaped article comprising said resin or composition, in particular a pipe.
US08101686B2 Interpolymer resin particles
Interpolymer resin particles comprised of 20% to 60% by weight of uncross-linked polyolefin e.g. polyethylene, polypropylene, and from 40% to 80% by weight based on the weight of the particles of a vinyl aromatic monomer, e.g. styrene, that is polymerized in a suspension process to form an interpenetrating network of polyolefin with polymerized vinyl aromatic monomer particles and having a gel content of 0 to 1.5% by weight based on the weight of the particles for improved processability in end-use applications and improved ESCR properties. The interpolymer resin particles have a VICAT softening temperature from about 90° C. to about 115° C., and a melt index from 0.2 to 35.0 g/10 minutes (Condition G). The particles can be mixed with a blowing agent to form extruded foam articles, such as foam board, and can be used in extrusion, injection molding, rotomolding, and thermoforming processes to form a layer, e.g. sheet, film, and as a tie layer in multi-layer structures to bind adjacent layers consisting of incompatible polymers, i.e. polystyrene and polyethylene for improved rigidity in multi-layer structures.
US08101683B2 Addition-curable silicone emulsion composition
An addition-curable silicone emulsion that exhibits stable curability even with a small amount of platinum. The curable emulsion composition is composed of an emulsion A and an emulsion B described below which are mixed together at the time of use, wherein the ratio of [number-average particle size of dispersed particles in emulsion A]/[number-average particle size of dispersed particles in emulsion B] is within a range from 0.4 to 2.0. The emulsion A comprises a specific alkenyl group-containing organopolysiloxane, a specific organohydrogenpolysiloxane, a nonionic surfactant, a polyvinyl alcohol and water, wherein the number-average particle size of the dispersed particles is within a range from 300 to 1,000 nm. The emulsion B comprises a specific alkenyl group-containing organopolysiloxane, a platinum-based complex, a nonionic surfactant, a polyvinyl alcohol and water, wherein the number-average particle size of the dispersed particles is within a range from 300 to 1,000 nm.
US08101679B2 Processing stabilizers for rubber compounding
The invention describes an improved method for the preparation of rubber compounds which comprises compounding the rubber and the components at 125-200° C. in the presence of an amount of 0.1-2% based on the weight of the rubber of a processing stabilizer of the formula (I) wherein R1 is hydrogen, C1-C20alkyl, styryl, α-methyl-styryl or —CH2—S—R3; or C1-C20alkyl substituted with C2-C20alkenyl, C3-C20alkinyl, C5-C9cycloalkyl, phenyl or tolyl; R2 is C1-C20alkyl or —CH2—S—R3, R3 is C1-C20alkyl; with phenyl, hydroxyl, cyano, formyl, acetyl or —O—CO—R5 substituted C1-C20alkyl; C2-C20alkenyl, C3-C20alkinyl, C5-C9cycloalkyl; or with hydroxyl, phenyl, 4-chloro-phenyl, 2-methoxycarbonylphenyl, p-tolyl, 1,3-benzthiazol-2-yl, —(CHR5)COOR6 or —(CHR5)nCONR7R8 substituted C5-C9cycloalkyl; R4 is hydrogen or methyl, R5 is hydrogen or C1-C6alkyl, R6 is C1-C20alkyl; with oxygen or sulfur interrupted C3-C20alkyl; C5-C9cycloalkyl, phenyl, benzyl or tolyl, R7 and R8 are independently of each other hydrogen or C1-C6alkyl, and n is 1 or 2.
US08101677B2 Multi-component room-temperature-curable silicone rubber composition
A multi-component room-temperature-curable silicone rubber composition comprising at least: (A) a diorganopolysiloxane, (B) a methoxy group-containing silicon compound comprising a bis(methoxysilyl)alkane or a organotrimethoxysilane (except amino group containing organotrimethoxysilane) (B-1), a methoxy group-containing carbasilatrane derivative (B-2), and an aminoalkylmethoxysilane (B-3) (wherein the weight ratio of constituent (B-2) to constituent (B-3) is in the range of (20:80) to (80:20)); and (C) a curing catalyst,the composition being packaged as two or more separately stored compositions wherein none of said separately stored compositions contain all said components (A), (B), and (C) simultaneously.
US08101676B2 Osteogenic paste compositions and uses thereof
Described are osteogenic paste compositions with enhanced osteoinductive properties for use in bone repair. Compositions comprising a quickly resorbable paste carrier, a more slowly resorbed mineral matrix, and Bone Morphogenetic Protein (BMP) or other osteogenic factor are described which enable increased osteoinductive activity while retaining a reliable scaffold for the formation of new bone at the implant site. Methods for making and methods for therapeutic use of the compositions are also disclosed.
US08101674B2 Rubber compound and molded article
A pharmaceutical/medical rubber compound contains the following components: (A) a composition obtainable by crosslinking (a) 100 parts by weight of an isobutylene polymer having terminal alkenyl groups with (d) a hydrosilyl-containing compound in the presence of (b) from 5 to 100 parts by weight of a polyolefin and (c) from 5 to 100 parts by weight of polybutene during melt kneading, and (B) an ultra-high molecular weight polyethylene powder. Compared with conventional thermoplastic elastomers, the pharmaceutical/medical rubber compound and its molded article are free from deformations and have sufficient permanent set resistance even under high temperature conditions, have excellent mechanical properties, low water absorption property, low reactivity and superb gas barrier properties, and can withstand high-temperature sterilization.
US08101673B2 Silica-containing UV-crosslinkable hardcoat coatings comprising urethane acrylates
The present invention relates to a UV-crosslinkable composition comprising a) unmodified, protonated silica nanoparticles; b) urethane acrylate; c) polar solvent; and d) UV initiator system, wherein the amount by weight of unmodified, protonated silica nanoparticles exceeds the content of urethane acrylate and is at least 50.1 wt. %, based on the dry weight of the coating, to the use of the composition in the coating of substrates, and to substrates coated with such formulations.
US08101672B2 Azeotrope-like compositions of 1,1,2,3,3-pentafluoropropene
The invention pertains to azeotrope-like compositions of 1,1,2,3,3-pentafluoropropene (HFC-1225yc) and any one of 1,1,1,2-tetrafluoropropene (HFC-1234yf) or the Z-isomer of 1,1,1,2,3-pentafluoropropene (HFC-1225yeZ), and uses thereof, including use in refrigerant compositions, refrigeration systems, blowing agent compositions, and aerosol propellants.
US08101670B2 Polymers with benzoxazine groups in their main chains
The present invention discloses polymers prepared through the Diels-Alder reaction with benzoxazine groups in their main chains. Moreover, polymers with high molecular weight could be successfully prepared via this method. Furthermore, the mentioned polymers are able to undergo crosslinking reaction by heat treatment. Heat energy causes the ring-opening reaction of benzoxazine in polymer main chains to undergo crosslinking reaction, and cross-linked polymers are thereby formed with great flexibility and high crosslinking degree.
US08101664B2 Urea foam
Provided, among other things, is a delivery module for a non-greasy, water-based urea composition comprising: an aerosol delivery device; within the aerosol delivery device, the urea composition comprising 20% or more urea by weight, non-greasy lipophilic component(s), and a frothing agent, the urea composition having a viscosity low enough to support aerosol delivery, and the urea composition effective to form a foam upon propellant-driven aerosol delivery; and within the aerosol delivery device, a propellant.
US08101662B2 Treatment of cancer with specific RXR agonists
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR effective dose.
US08101661B2 Polar hydrophilic prodrugs and non-standard amino acid conjugates of amphetamine and other stimulants and processes for making and using the same
Disclosed are polar, hydrophilic stimulant prodrug compositions comprising at least one stimulant chemically attached to a polar hydrophilic ligand, a salt thereof, a derivative thereof, or a combination thereof. Also disclosed are non-standard amino acid conjugates of amphetamine. Methods of making and using the same are also disclosed.
US08101658B2 Nitric oxide donating prostamides
Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
US08101656B2 Use of 2,2-dimethyl-3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4,5]dec-3-en-4-yl butanoate for controlling acarides
The present invention relates to the use of 2,2-dimethyl-3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl butanoate for controlling acarids in hops, kiwi fruit, soft fruit, nuts, coffee, tropical fruit, spices and conifers.
US08101645B2 Thienopyrroles and pyrrolothiazoles as new therapeutic agents
The present invention is directed to novel compounds of Formula (I) wherein the variables are defined as herein. The compounds of Formula (I) are useful as CRTH2 antagonists and as such would be useful in treating certain conditions and diseases, especially asthma, allergic asthma, allergic inflammation, rhinitis, allergic rhinitis or atopic dermatitis.
US08101640B2 Antibacterial agents
Antibacterial compounds of formula I are provided: As well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.
US08101638B2 6-substituted nicotinamide derivatives as opioid receptor antagonists
A compound of the formula (I) or a pharmaceutically acceptable salt, enantiomer, racemate, diasteromers or mixtures thereof, or a solvate thereof, formulations and methods of use thereof, as opioid receptor antagonists are disclosed wherein the variables are as described herein.
US08101635B2 Calcium blockers to treat proliferative vitreoretinopathy
Glutamate causes migration and proliferation of retinal pigment epithelium and/or glial cells, and glutamate antagonists can prevent, treat or reduce retinal pigment epithelium and/or glial migration and the subsequent development of proliferative vitreoretinopathy. Avoidance or management of proliferative vitreoretinopathy can be achieved by administering to the patient a compound capable of reducing glutamate-induced retinal cell migration in a concentration effective to reduce such migration.
US08101634B2 Bicyclic compounds and use as antidiabetics
The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.
US08101633B2 Preparation and utility of substituted imidazopyridine compounds with hypnotic effects
The present disclosure is directed to modulators of GABAA receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of sleep disorders and/or for providing a patient in need with a hypnotic, anxiolytic or anti-convulsive effect are described.
US08101627B2 Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
The present invention provides stereoisomers and stereoisomeric mixtures of 3-aminocarbonyl-bicycloheptene-2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers.
US08101625B2 Pyrimidinones as Casein Kinase II (CK2) modulators
A compound having Formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1 and R2 are defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.
US08101624B2 Quinazoline derivatives
The invention discloses quinazoline derivatives or salts thereof, which possess PDE9-inhibiting activity and are useful as treating agents of dysuria and the like, the derivatives being represented by the formula (I) in the formula, R1 stands for phenyl or aromatic heterocyclic group which are optionally substituted with 1-3 substituents selected from halogen, C1-6 alkyl, C1-6 haloalkyl containing 1-6 halogen atoms and C1-6 alkoxy; and n is an integer of 1-3.
US08101622B2 Pyridopyrimidinone inhibitors of PI3Kα and mTOR
The invention is directed to Compounds of Formula I: optionally as a single stereoisomer or mixture of stereoisomers thereof, and additionally optionally as a pharmaceutically acceptable salt thereof; as well as methods of making and using the compounds.
US08101621B2 Aminopyridine derivatives having aurora a selective inhibitory action
The present invention relates to a compound of general formula I: wherein: n1 and n2 are the same or different, and are 0 or 1; R is aryl, heteroaryl, etc.; Re is hydrogen atom or lower alkyl; two groups selected from four groups consisting of (i) either one of Ra1 and Ra1′, (ii) either one of Ra2 and Ra2′, (iii) either one of Rb1 and Rb1′, and (iv) either one of Rb2 and Rb2′, are combined to form —(CH2)n— where n is 1, 2 or 3; and among Ra1, Ra1′, Ra2, Ra2′, Rb1, Rb1′, Rb2 and Rb2′, the groups which do not form —(CH2)n— are each independently hydrogen atom, etc.; X1, X2, X3 and X4 are each independently CH, N, etc.; Y1, Y2, Y3 and Y4 are the same or different and are CH or N, etc.; W is a 5-membered aromatic heterocyclic group, or a pharmaceutically acceptable salt or ester thereof.
US08101616B2 Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
US08101608B2 Compounds and compositions as protein kinase inhibitors
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-II, Rsk1, SGK, TrkA, TrkB and TrkC kinases.
US08101607B2 Pharmaceutical compounds
Provided herein are methods of treating diseases or disorders arising from abnormal cell growth, function or behavior associated with PI3 kinase, which method includes administering to a patient in need thereof a compound that is a fused pyrimidine of formula (I):
US08101602B2 Pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mTOR inhibitors
There is provided a compound of formula I: or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.
US08101601B2 Aminoacyl prodrug derivatives and medicaments for the treatment of thromboembolitic disorders
The present application relates to prodrug derivatives of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-morpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of thromboembolic disorders.
US08101598B2 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use
This invention relates to novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors.Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
US08101597B2 Quetiapine salts and their polymorphs
The present invention relates to novel and stable salt forms of quetiapine, processes for preparation, pharmaceutical compositions, and method of treating thereof. More particularly, the present invention provides novel acid addition salts of quetiapine wherein the acid counter ion is provided by an acid selected from the group consisting of benzene sulfonic acid, dibenzoyl-L-(+)-tartaric acid and di-p-toluoyl-L-(+)-tartaric acid. The present invention also provides novel polymorphic forms of quetiapine salts selected from the group consisting of quetiapine hydrobromide, quetiapine sulfate, quetiapine nitrate and quetiapine citrate.
US08101593B2 Formulations of deoxycholic acid and salts thereof
The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.
US08101592B2 Hexahydro-cyclooctyl pyrazole cannabinoid modulators
This invention is directed to a hexahydro-cyclooctyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
US08101590B2 9-aminocarbonylsubstituted derivatives of glycylcyclines
This invention provides compounds of Formula I having the structure where R1, R2, R3 and A are defined in the specification or a pharmaceutically acceptable salt thereof useful as antibacterial agents. Compounds according to Formula (II): where Q, R4, R5, R6 and R10 and A are defined in the specification are useful as chemical intermediates.
US08101589B2 Nitric oxide-releasing molecules
This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
US08101587B2 Kits for nutrition supplementation
The present invention relates to methods of co-administration of various vitamin and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.
US08101583B2 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with fluorine, method for producing the same, drugs containing said compounds and use thereof
This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with fluorine, method for producing the same, drugs containing said compounds and use thereof.
US08101579B2 Methods and compositions for the treatment of gastrointestinal disorders
Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.
US08101576B2 Compounds and their effects on feeding behaviour
The invention features peptides for the treatment or prevention of obesity, diabetes or co-morbidities of obesity; for reduction of appetite, food intake, calorie intake, body weight, or body weight gain; and for increase of energy expenditure in a subject.
US08101573B2 α-conotoxin MII analogs
The invention relates to novel conopeptides and/or novel uses of conopeptides. The conopeptides of the invention are analogs of α-Conotoxin MII that are selective for α6-containing nAChRs as described herein.
US08101572B2 Methods for promoting wound healing and/or reducing scar formation
The present invention provides methods for promoting wound healing and/or reducing scar formation, by administering to an individual in need thereof one or more of the heat shock protein 20-derived polypeptides disclosed herein.
US08101571B2 Treatment methods using NGF variants
NGF variants which have trkC-binding activity and trkC-signal inducing activity are provided. The variants optionally have trkA or trkB binding and signal induction activity. The NGF variants of the present invention are useful in the treatment of neuronal disorders. Nucleic acids and expression vectors encoding the NGF variant neurotrophins are also provided.
US08101570B2 Single branch heparin-binding growth factor analogs
A heparin-binding growth factor (HBGF) analog having two substantially similar sequences (homodimeric sequences) branched from a single amino acid residue, where the sequences are analogs of a particular HBGF that binds to a heparin-binding growth factor receptor (HBGFR), or alternatively that bind to a HBGFR without being an analog of any particular HBGF. The homodimeric sequences may be derived from any portion of a HBGF. The synthetic HBGF analog may be an analog of a hormone, a cytokine, a lymphokine, a chemokine or an interleukin, and may bind to any HBGFR. Further provided are preparations for medical devices, pharmaceutical compositions and methods of using the same.
US08101569B2 Energy status of an individual by enhanced production of an endogenous fuel source
The present invention relates to a method of improving the energy status of an individual by enhancing the usage of lactate. Improved lactate usage is accomplished through a composition comprising lactate precursors, adrenergic receptor agonists and insulinotropic agents.
US08101567B2 Heteroaryl-containing tripeptide HCV serine protease inhibitors
The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
US08101563B2 Proteases from gram-positive organisms
The present invention relates to the identification of novel metallo-proteases (MP) in Gram-positive microorganisms. The present invention provides the nucleic acid and amino acid sequences for Bacillus MP. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding MP. The present invention also provides host cells further comprising nucleic acid encoding desired heterologous proteins such as enzymes. The present invention also provides cleaning compositions comprising an MP of the present invention.
US08101559B2 Polyalkyl (meth)acrylate copolymers having outstanding properties
Copolymers are obtainable by polymerizing a monomer composition containing a) 0% to 40% by weight of one or more ethylenically unsaturated ester compounds of the formula (I), b) 10% to 99.9% by weight of one or more ethylenically unsaturated ester compounds of the formula (II), c) 0% to 80% by weight of one or more ethylenically unsaturated ester compounds of the formula (III), d) 0.1% to 30% by weight of one or more ethylenically unsaturated, polar ester compounds of the formula (IV), and e) 0% to 50% by weight of comonomer, based in each case on the total weight of the ethylenically unsaturated monomers.
US08101558B2 Lubricating oil compositions
A composition containing an oil of lubricating viscosity in a concentrate-forming or major amount; and, as an additive component, an oil-soluble or oil dispersible mononuclear molybdenum compound having a molybdenum atom having bonded thereto one or more diazenide ligands and one or more hydrocarbyl group-carrying ligands, other than diazenide ligands, the hydrocarbyl groups conferring oil-solubility or oil-dispersibility on the molybdenum compound.
US08101555B2 Spotting fluids containing syrups
A spotting fluid is provided and the spotting fluid consists essentially of: syrup, syrup solids and a liquid medium, said syrup and syrup solids are derived from a group consisting essentially of agave syrup, barley syrup, sugar syrup, beets syrup, birch syrup, rice syrup, cane syrup, chocolate syrup, coconut syrup, corn syrup, date syrup, fruit syrup, golden syrup, high fructose corn syrup, inverted sugar syrup, karo syrup, citrus fruit syrup, maple syrup, molasses, Muscavado syrup, palm syrup, rice syrup, sorghum syrup, Turbinado syrup, vanilla syrup and mixtures and blends thereof, and the liquid medium is selected from a group consisting of water, purified water, ionized water, salt water and mixtures thereof.
US08101550B2 Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents
The present invention relates to new insecticides of the formula (I) in which R1, R2, R3, R4, R5, R6, A, Q and n can have the definitions stated in the description, to a number of processes for preparing them and to their use as active compounds, more particularly to their use as pest control compositions.
US08101545B2 Coating compositions for marking substrates
The present invention provides coating compositions for marking substrates, which comprises a color former, an amine salt of an organic metal compound, a binder, a solvent, and optionally additional components, wherein the amine salt of the organic metal compound is of formula (I) in which X is silicon or boron, and E and F are the same or different and are selected from the group consisting of a, b, c, d, e, f, g, h in which R6 and R7 are the same or different are hydrogen, C1-4-alkyl, C1-4-alkoxy, halogen, amino or carboxy, and for X=silicon o=1 and p=0, and R1 is aryl, aralkyl or C1-4-alkyl, or o=1 and p=1, and R1 and R2 together form a one residue selected from the group consisting of a, b, c, d, e, f, g and h, and for X=boron o=0 and p=0, and R3, R4 and R5 are the same or different and are hydrogen, C1-12-alkyl, C1-6-hydroxyalkyl, allyl, aralkyl or arylsulfonyl, in which aralkyl or arylsulfonyl can be substituted with C1-4-alkyl, or R3 and R4 together with the nitrogen to which they are attached form a morpholino or piperidino ring. The present invention also provides a process for the preparation of the composition of the present invention, substrates coated with these compositions, a process for preparing coated substrates, a process for preparing a marked substrate using these compositions, a marked substrate obtainable by the latter process and amine salts of the organic metal compounds of formula I.
US08101544B2 Coating compositions for marking substrates
The present invention provides coating compositions for marking substrates, which comprise a colour former in an amount of from 0.01 to 50%, a metal salt of a carboxylic acid in an amount of from 0.01 to 50%, a binder in an amount of from 1 to 80% and an organic solvent in an amount of from 1 to 99%, wherein each amount is by weight based on the weight of the composition. The present invention also provides a process for the preparation of the composition of the present invention, substrates coated with these compositions and a process for preparing a marked substrate using these compositions.
US08101541B2 Catalyst for dehydrogenation of hydrocarbons
A stationary or fluid bed dehydrogenation catalyst containing an alumina carrier, with chromium and alkali metals consisting of only sodium and potassium, added as promoters. The resultant catalyst demonstrates greater selectivity and olefin yield than prior art dehydrogenation catalysts, especially after aging.
US08101540B2 Catalysts for low temperature oxidation of carbon monoxide
CuO—ZnO—CeO2 catalyst and aged CuO—ZnO catalyst catalytically active for low temperature oxidation of carbon monoxide. The catalysts are co-precipitated, filtered, washed, dried, and calcined. The catalysts can be incorporated into a component of a cigarette or can be used to reduce the concentration of carbon monoxide from a vehicle exhaust emission, a gas used in a laser, a gas used in a fuel cell and/or ambient air undergoing air filtration.
US08101539B2 Purifying catalyst
A purifying catalyst includes catalyst powder composed of a transition metal oxide of which an average particle diameter is within 1 nm to 2 μm and in which an electron binding energy of oxygen is shifted to an energy side lower than 531.3 eV. The purifying catalyst shows good purification performance even when noble metal is not contained as an essential component.
US08101536B2 Glass-free microwave dielectric ceramics and the manufacturing method thereof
A glass-free microwave dielectric ceramic that can be sintered at low temperature is provided. The glass-free microwave dielectric ceramic composition includes (M1-x2+M′x2+)N4+B2O6 (wherein M and M′ are different each other, each being one among Ba, Ca and Sr; N is one among Sn, Zr and Ti; and 0
US08101531B1 Plasma-activated deposition of conformal films
Methods and hardware for depositing thin conformal films using plasma-activated conformal film deposition (CFD) processes are described herein. In one example, a method for forming a thin conformal film comprises, in a first phase, generating precursor radicals off of a surface of the substrate and adsorbing the precursor radicals to the surface to form surface active species; in a first purge phase, purging residual precursor from the process station; in a second phase, supplying a reactive plasma to the surface, the reactive plasma configured to react with the surface active species and generate the thin conformal film; and in a second purge phase, purging residual reactant from the process station.
US08101526B2 Method of making diamond nanopillars
A method for fabricating diamond nanopillars includes forming a diamond film on a substrate, depositing a metal mask layer on the diamond film, and etching the diamond film coated with the metal mask layer to form diamond nanopillars below the mask layer. The method may also comprise forming diamond nuclei on the substrate prior to forming the diamond film. Typically, a semiconductor substrate, an insulating substrate, a metal substrate, or an alloy substrate is used.
US08101519B2 Mold, manufacturing method of mold, method for forming patterns using mold, and display substrate and display device manufactured by using method for forming patterns
The present invention relates to a mold, a manufacturing method of the mold, and a method of forming patterns using the mold. The mold may include a main body having a convex portion and a recess portion, and a polymer layer formed over the main body by processing a surface of the main body with a high molecular weight material through a surface treatment.
US08101516B2 Method of forming contact hole pattern in semiconductor integrated circuit device
A block film is formed on a region which includes a region of an insulating layer where a first hole is to be formed, and in which no second hole is to be formed, and a resist film having openings for forming the first and second holes is formed on the block film and insulating layer. Etching is performed by using the resist film as a mask, thereby forming the first hole in the block film and insulating layer, and the second hole in the insulating layer. The depth of the first hole from the upper surface of the insulating layer is smaller than that of the second hole, so the first hole does not reach the semiconductor substrate.
US08101515B2 Methods of manufacturing semiconductor devices having contact plugs in insulation layers
Methods of manufacturing semiconductor devices are provided in which a first contact plug is formed on a first active region in a substrate and a second contact plug is formed on a second active region in the substrate. A height of an upper surface of the second contact plug from the substrate is greater than a height of an upper surface of the first contact plug from the substrate. A third contact plug is formed on the second contact plug. A first spacer is formed on a side surface of the third contact plug. A third interlayer insulation layer is formed that covers the third contact plug. The third interlayer insulation layer is patterned to form a third opening that exposes the first contact plug. A fourth contact plug is formed in the third opening that is electrically connected to the first contact plug.
US08101513B2 Manufacture method for semiconductor device using damascene method
(a) A recess is formed through an insulating film formed over a semiconductor substrate. (b) After the recess is formed, a temperature of the substrate is raised to 300° C. or higher at a temperature rising rate of 10° C./s or slower and a first degassing process is executed. (c) After the first degassing process, a conductive film is deposited on the insulating film, the conductive film being embedded in the recess. (d) The deposited conductive film is polished until the insulating film is exposed. It is possible to suppress occurrence of defects during CMP to be performed after a conductive member is deposited on the surface of the insulating film having a recess formed therethrough.
US08101512B2 Method of enhancing lithography capabilities during gate formation in semiconductors having a pronounced surface topography
In a mesa isolation configuration for forming a transistor on a semiconductor island, an additional planarization step is performed to enhance the uniformity of the gate patterning process. In some illustrative embodiments, the gate electrode material may be planarized, for instance, on the basis of CMP, to compensate for the highly non-uniform surface topography, when the gate electrode material is formed above the non-filled isolation trenches. Consequently, significant advantages of the mesa isolation strategy may be combined with a high degree of scalability due to the enhancement of the critical gate patterning process.
US08101507B2 Semiconductor device manufacturing method and semiconductor device manufacturing apparatus
There is provided a semiconductor device manufacturing apparatus and a semiconductor device manufacturing method capable of recovering a damage of a low dielectric insulating film exposed to CO2 plasma to obtain the low dielectric insulating film in a good state, thus improving performance and reliability of a semiconductor device. The semiconductor device manufacturing method includes: an etching process for etching a low dielectric insulating film formed on a substrate; a CO2 plasma process for exposing the substrate to CO2 plasma after the etching process; and a UV process for irradiating UV to the low dielectric insulating film after the CO2 plasma process.
US08101506B2 Method for producing a buried n-doped semiconductor zone in a semiconductor body and semiconductor component
A method for producing a buried n-doped semiconductor zone in a semiconductor body. In one embodiment, the method includes producing an oxygen concentration at least in the region to be doped in the semiconductor body. The semiconductor body is irradiated via one side with nondoping particles for producing defects in the region to be doped. A thermal process is carried out. The invention additionally relates to a semiconductor component with a field stop zone.
US08101504B2 Semiconductor chip fabrication method
A semiconductor chip fabrication method including a modified layer forming step of applying a laser beam having a transmission wavelength to the semiconductor wafer from the back side of the semiconductor wafer along the streets formed on the front side of the semiconductor wafer so that a focal point of the laser beam is set inside the semiconductor wafer, thereby forming a modified layer in the semiconductor wafer along each street, a metal film deposition step of depositing a metal film on the back side of the semiconductor wafer after the modified layer forming step, a semiconductor wafer attaching step of attaching the semiconductor wafer to an adhesive tape supported to an annular frame, and a semiconductor wafer dividing step of applying an external force to the semiconductor wafer in the condition where the semiconductor wafer is attached to the adhesive tape to thereby divide the semiconductor wafer with the metal film into the individual semiconductor chips along the modified layer formed along each street.
US08101503B2 Method of producing a thin layer of semiconductor material
A semiconductor structure includes a thin semiconductor layer fixed on an applicator or flexible support, the thin layer having an exposed surface characterized by fractured solid bridges spaced apart by cavities. A method of producing the thin layer of semiconductor material includes implanting ions into the semiconductor wafer to define a reference plane, where the ion dose is above a minimum dose, but below a critical dose so as to avoid degrading the wafer surface. The method further includes applying a thermal treatment to define a layer of microcavities and applying stress to free the thin layer from the wafer.
US08101499B2 Formation of TSV backside interconnects by modifying carrier wafers
An integrated circuit structure includes a semiconductor wafer, which includes a first notch extending from an edge of the semiconductor wafer into the semiconductor wafer. A carrier wafer is mounted onto the semiconductor wafer. The carrier wafer has a second notch overlapping at least a portion of the first notch. A side of the carrier wafer facing the semiconductor wafer forms a sharp angle with an edge of the carrier wafer. The carrier wafer has a resistivity lower than about 1×108 Ohm-cm.
US08101497B2 Self-aligned trench formation
Methods for forming a semiconductor device include forming self-aligned trenches, in which a first set of trenches is used to align a second set trenches. Methods taught herein can be used as a pitch doubling technique, and may therefore enhance device integration. Further, employing a very thin CMP stop layer, and recessing surrounding materials by about an equal amount to the thickness of the CMP stop layer, provides improved planarity at the surface of the device.
US08101496B2 Method of manufacturing ball grid array type semiconductor device
A BGA type semiconductor device having high reliability is offered. A pad electrode is formed on a surface of a semiconductor substrate and a glass substrate is bonded to the surface of the semiconductor substrate. A via hole is formed from a back surface of the semiconductor substrate to reach a surface of the pad electrode. An insulation film is formed on an entire back surface of the semiconductor substrate including an inside of the via hole. A cushioning pad is formed on the insulation film. The insulation film is removed from a bottom portion of the via hole by etching. A wiring connected with the pad electrode is formed to extend from the via hole onto the cushioning pad. A conductive terminal is formed on the wiring. Then the semiconductor substrate is separated into a plurality of semiconductor dice.
US08101486B2 Methods for forming isolated fin structures on bulk semiconductor material
Methods are provided for fabricating a semiconductor device. A method comprises forming a layer of a first semiconductor material overlying the bulk substrate and forming a layer of a second semiconductor material overlying the layer of the first semiconductor material. The method further comprises creating a fin pattern mask on the layer of the second semiconductor material and anisotropically etching the layer of the second semiconductor material and the layer of the first semiconductor material using the fin pattern mask as an etch mask. The anisotropic etching results in a fin formed from the second semiconductor material and an exposed region of first semiconductor material underlying the fin. The method further comprises forming an isolation layer in the exposed region of first semiconductor material underlying the fin.
US08101482B2 Method of fabricating semiconductor device having transistor
Provided is a method of fabricating a semiconductor device having a transistor. The method includes forming a first gate trench in a first active region of a semiconductor substrate. A first gate layer partially filling the first gate trench is formed. Ions may be implanted in the first gate layer and in the first active region on both sides of the first gate layer such that the first gate layer becomes a first gate electrode of a first conductivity type and first impurity regions of the first conductivity type are formed on both sides of the first gate electrode.
US08101478B2 TFT MONOS or SONOS memory cell structures
A device having thin-film transistor (TFT) metal-oxide-nitride-oxide-semiconductor (MONOS) or semiconductor-oxide-nitride-oxide-semiconductor (SONOS) memory cell structures is provided. The device includes a substrate, a dielectric layer on the substrate, and one or more source or drain regions being embedded in the dielectric layer. the dielectric layer being associated with a first surface. Each of the one or more source or drain regions includes an N+ polysilicon layer on a diffusion barrier layer which is on a conductive layer. The N+ polysilicon layer has a second surface substantially co-planar with the first surface. Additionally, the device includes a P− polysilicon layer overlying the co-planar surface, an oxide-nitride-oxide (ONO) layer overlying the P− polysilicon layer; and at least one control gate overlying the ONO layer. In one embodiment, the control gate is made of a metal layer. In another embodiment, the control gate is made of a P+ polysilicon layer. A method of making the same memory cell structure is provided and can be repeated to integrate the structure three-dimensionally.
US08101470B2 Foil based semiconductor package
The present inventions relate to methods and arrangements for using a thin foil to form electrical interconnects in an integrated circuit package. One embodiment of the present invention involves attaching multiple dice to a foil carrier structure. The foil carrier structure is made of a thin foil that is bonded to a carrier. The dice and at least a portion of the metallic foil is then encapsulated with a molding material. The carrier is removed, leaving behind a molded foil structure. The exposed foil is patterned and etched using photolithographic techniques to define multiple device areas in the foil. Each device area includes multiple conductive lines. Afterwards, portions of the conductive lines are covered with a dielectric material and other portions are left exposed to define multiple bond pads in the device area. The molded foil structure can be singulated to form multiple integrated circuit packages.
US08101467B2 Liquid crystal display device and method for manufacturing the same, and liquid crystal television receiver
At least one or more of a conductive layer which forms a wiring or an electrode and a pattern necessary for manufacturing a display panel such as a mask for forming a predetermined pattern is formed by a method capable of selectively forming a pattern to manufacture a liquid crystal display device. A droplet discharge method capable of forming a predetermined pattern by selectively discharging a droplet of a composition in accordance with a particular object is used as a method capable of selectively forming a pattern in forming a conductive layer, an insulating layer, or the like.
US08101465B2 Method of fabricating a semiconductor device with a back electrode
A semiconductor device capable of stabilizing operations thereof is provided. This semiconductor device comprises a substrate provided with a region having concentrated dislocations at least on part of the back surface thereof, a semiconductor element layer formed on the front surface of the substrate, an insulator film formed on the region of the back surface of the substrate having concentrated dislocations and a back electrode formed to be in contact with a region of the back surface of the substrate other than the region having concentrated dislocations.
US08101464B2 Microelectronic devices and methods for manufacturing microelectronic devices
Microelectronic devices and methods for manufacturing microelectronic devices are disclosed herein. One such method includes forming a plurality of apertures in a substrate with the apertures arranged in an array, and, after forming the apertures, attaching the substrate to a lead frame having a plurality of pads with the apertures in the substrate aligned with corresponding pads in the lead frame. Another method includes providing a partially cured substrate, coupling the partially cured substrate to a plurality of leads, attaching a microelectronic die to the leads, and electrically connecting the microelectronic die to the leads.
US08101462B2 Method for manufacturing semiconductor device, and semiconductor device
A method for manufacturing a semiconductor device includes: when bonding a bump of an IC chip to a bonding position of a wiring pattern that is formed on an insulating film base member and has a surface covered by a plating layer, forming a plating layer around the bonding position among the wiring pattern at least in an outer peripheral section of a peeled surface of a portion of the wiring pattern peeled from the film base member.
US08101461B2 Stacked semiconductor device and method of manufacturing the same
A method of manufacturing a semiconductor device includes: (a) half-dicing a semiconductor wafer including plural semiconductor chips, thereby forming dicing grooves in the semiconductor wafer, wherein each semiconductor chip includes a circuit and pads and wherein the semiconductor wafer includes: a first surface on which the circuit and the pads are formed; and a second surface opposite to the first surface, (b) connecting the pads to each other by conductive connectors; (c) sealing the first surface of the semiconductor wafer, the dicing grooves and the conductive connectors with a resin; (d) grinding the second surface of the semiconductor wafer, thereby forming a group of sealed chips; (e) dividing the group of sealed chips into individual sealed chips; (f) mounting and stacking the individual sealed chips on a wiring substrate having connection terminals thereon; and (g) electrically-connecting the conductive connectors and the connection terminals using a conductive member.
US08101459B2 Methods for assembling semiconductor devices in stacked arrangements by positioning spacers therebetween
A method for assembling semiconductor devices includes providing a first semiconductor device, securing spacers to noncircuit bond pads of the first semiconductor device, and positioning a second semiconductor device on the spacers. Adhesive material may be applied to a surface of one or both of the first and second semiconductor devices prior to positioning of the second semiconductor device, or introduced between first and second semiconductor devices. The noncircuit bond pads may be electrically isolated from other structures of the first semiconductor device or communicate with a ground or reference voltage plane, in which case the back side of the second semiconductor device may communicate with the ground or reference voltage plane upon being positioned against the spacers. Additional semiconductor devices may be added to the assembly. The first semiconductor device may be associated with a substrate. Assemblies and packages at least partially fabricated by the method are also disclosed.
US08101451B1 Method to form a device including an annealed lamina and having amorphous silicon on opposing faces
A semiconductor assembly is described in which a support element is constructed on a surface of a semiconductor lamina. Following formation of the thin lamina, which may have a thickness about 50 microns or less, the support element is formed, for example by plating, or by application of a precursor and curing in situ, resulting in a support element which may be, for example, metal, ceramic, polymer, etc. This is in contrast to a rigid or semi-rigid pre-formed support element which is affixed to the lamina following its formation, or to a donor wafer from which the lamina is subsequently cleaved. Fabricating the support element in situ may avoid the use of adhesives to attach the lamina to a permanent support element; such adhesives may be unable to tolerate processing temperatures and conditions required to complete the device. In some embodiments, this process flow allows the lamina to be annealed at high temperature, then to have an amorphous silicon layer formed on each face of the lamina following that anneal. A device may be formed which comprises the lamina, such as a photovoltaic cell.
US08101449B2 Process for altering thermoelectric properties of a material
A process for altering the thermoelectric properties of an electrically conductive material is provided. The process includes providing an electrically conducting material and a substrate. The electrically conducting material is brought into contact with the substrate. A thermal gradient can be applied to the electrically conducting material and a voltage applied to the substrate. In this manner, the electrical conductivity, the thermoelectric power and/or the thermal conductivity of the electrically conductive material can be altered and the figure of merit increased.
US08101445B2 Thin film transistor array panel and method for manufacturing the same
A thin film transistor array panel according to the present invention includes: an insulation substrate having a display area and a peripheral area; a plurality of thin film transistors disposed in the display area; a plurality of gate lines connected to the thin film transistors; a plurality of data lines connected to the thin film transistors; a driving unit disposed in the peripheral area of the insulation substrate, and controlling the thin film transistor; a plurality of signal lines connecting between the driving unit and the gate lines or the data lines; and a dummy pattern overlapping the signal line and made of a transparent conductive material.
US08101444B2 Method for manufacturing semiconductor device
Electric characteristics of a thin film transistor including a channel formation region including a microcrystalline semiconductor are improved. The thin film transistor includes a gate electrode, a gate insulating film formed over the gate electrode, a microcrystalline semiconductor layer formed over the gate insulating film, a semiconductor layer which is formed over the microcrystalline semiconductor layer and includes an amorphous semiconductor, and a source region and a drain region which are formed over the semiconductor layer. A channel is formed in the microcrystalline semiconductor layer when the thin film transistor is placed in an on state, and the microcrystalline semiconductor layer includes an impurity element for functioning as an acceptor. The microcrystalline semiconductor layer is formed by a plasma-enhanced chemical vapor deposition method. In forming the microcrystalline semiconductor layer, a process gas is excited with two or more kinds of high-frequency electric power with different frequencies.
US08101442B2 Method for manufacturing EL display device
A manufacture process of a thin film transistor mounted on an EL display device is simplified. A thin film transistor is manufactured by stacking a first conductive film, an insulating film, a semiconductor film, an impurity semiconductor film, and a second conductive film; forming a first resist mask over the stacked films; performing first etching to form a thin-film stack body; performing second etching by side etching is conducted on the thin-film stack body to form a gate electrode layer; and forming a source and drain electrode layer and the like with use of a second resist mask. An EL display device is manufactured using the thin film transistor.
US08101441B2 Method of manufacturing light-emitting device
A method of manufacturing a light-emitting device includes, when sealing a light-emitting element on a mounting portion by a glass material softened by heating or when processing the glass material after the sealing, producing a concave portion partially on the glass material by partially contacting and pressing a die against an upper surface of the glass material such that a part of the upper surface being not in contact with the die is deformed and forms a curved surface.
US08101440B2 Method for fabricating light emitting diode chip
A method for fabricating a light emitting diode chip is provided. Firstly, a semiconductor device layer is formed on a substrate. Afterwards, a current spreading layer is formed on a portion of the semiconductor device layer. Then, a current blocking layer and a passivation layer are formed on a portion of the semiconductor device layer not covered by the current spreading layer. Finally, a first electrode is formed on the current blocking layer and the current spreading layer. Moreover, a second electrode is formed on the semiconductor device layer.
US08101438B2 Method of fabricating printhead integrated circuit with backside electrical connections
A method of fabricating a printhead integrated circuit configured for backside electrical connections. The method comprises the steps of: (a) providing a wafer comprising a plurality of partially-fabricated nozzle assemblies on a frontside of the wafer and through-silicon connectors extending from the frontside towards a backside of the wafer; (b) depositing a conductive layer on the frontside of said wafer and etching to form an actuator for each nozzle assembly and a frontside contact pad over a head of each through-silicon connector; (c) performing further MEMS processing steps to complete formation of nozzle assemblies ink supply channels through-silicon connectors; and (d) dividing the wafer into individual printhead integrated circuits. Each printhead integrated circuit thus formed is configured for backside-connection to the drive circuitry via the through-silicon connectors the contact pads.
US08101435B2 Fabrication method for semiconductor device
A semiconductor device fabrication method can improve yield of semiconductor devices and decrease (or prevent) waste of non-defective semiconductor chips. This fabrication method has a step of performing characteristic inspection after packaging a semiconductor chip every time a semiconductor chip layer is formed. The fabrication method makes another semiconductor chip layer on this semiconductor chip layer only when the inspection indicates that the semiconductor chip is a non-defective product.
US08101430B2 Fluorescent sensor based on two fluorescent moieties one of which is a semiconductor nanocrystal and methods of using and making
Binding an analyte can cause a change in fluorescence emission of a sensor. The change in fluorescence can be related to the amount of analyte present. The sensor can include a semiconductor nanocrystal linked to a fluorescent moiety. Upon excitation, the fluorescent moiety can transfer energy to the semiconductor nanocrystal, or vice versa.
US08101428B2 Microfluidic systems and control methods
The systems and methods disclosed herein include a microfluidic system, comprising a pneumatic manifold having a plurality of apertures, and a chip manifold having channels disposed therein for routing pneumatic signals from respective ones of the apertures to a plurality of valves in a microfluidic chip, wherein the channels route the pneumatic signals in accordance with a configuration of the plurality of valves in the microfluidic chip.
US08101427B2 Methods for detecting vitamin D metabolites by mass spectrometry
Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.
US08101426B2 System and method for the measurement of multiple fluorescence emissions in a flow cytometry system
A system and method for the measurement of multiple fluorescence emissions in a flow cytometry system is disclosed where each excitation light source is modulated with a different frequency. A single detector is used to collect the fluorescent emissions excited by all light sources, and the emissions are segregated using Fourier Transform techniques. Systems and methods for the correction of inter-beam coincidence are also disclosed.
US08101425B1 Particles embedded in a porous substrate for removing target analyte from a sample
The invention provides devices, test kits and methods for removing target agents from a sample. The device contains one or more porous matrices having pore sizes larger than 10 μm, and a plurality of particles impregnated therein. The target agents attach the device and are removed from the sample.
US08101421B2 Volumetric induction phase shift detection system for determining tissue water content properties
A method of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample. An apparatus for determining the condition of a bulk tissue sample, having: a first induction coil (or antenna); a second induction coil (or antenna); an alternating current power supply connected to the first induction coil (or antenna), the alternating current power supply configured to generate a spectrum of currents (or voltage) in the first induction coil (or antenna); and a measurement system connected to the second induction coil (or antenna), wherein the measurement system is configured to measure a phase shift difference in the spectrum of currents (or voltages) between the first and second induction coils (or antennae) when the first and second induction coils (or antennae) are positioned on opposite sides of a tissue sample.
US08101418B2 Carbon measurement in aqueous samples using oxidation at elevated temperatures and pressures
Apparatus and methods for measuring the concentrations of organic and inorganic carbon, or of other materials, in aqueous samples are described, together with related, specially adapted components and sub-assemblies and related control, operational and monitoring systems.
US08101412B2 Method of enhancing proliferation and/or hematopoietic differentiation of stem cells
The present invention provides a method for enhancing the proliferation and/or hematopoietic differentiation and/or maintenance of mammalian stem cells. The method is useful for generating expanded populations of hematopoietic stem cells (HSCs) and thus mature blood cell lineages. This is desirable where a mammal has suffered a decrease in hematopoietic or mature blood cells as a consequence of disease, radiation or chemotherapy. The method of the present invention comprises increasing the intracellular level of a cdx in stem cells, including hematopoietic stem cells, in culture, either by providing an exogenous cdx protein to the cell, or by introduction into the cell of a genetic construct encoding a cdx. The cdx is selected from the cdx family and includes cdx1, cdx2, or cdx4. The cdx may be a wild type protein appropriate for the species from which the cells are derived, or a mutant form of the protein.
US08101404B2 Plasma extraction apparatus
A system that is suitable for extracting plasma from blood received from a blood supply is provided. The system comprises a housing, an inlet opening for receiving the blood, a filtration chamber comprising a membrane, and a plasma compartment. The membrane forms a barrier between the blood and the plasma extracted from the blood, and the plasma compartment collects the plasma extracted from the blood. In some embodiments, the system comprises a plasma flow path compression chamber for pulling plasma across the membrane. In some embodiments, the system comprises a blood flow path compression chamber for facilitating blood flow. Some embodiments of the system further comprise means for measuring plasma and blood analytes using spectroscopic and biosensor techniques.
US08101401B2 Container and device for generating electric fields in different chambers
The invention concerns a container 1 with chambers 2 which each comprise at least one pair of electrodes including a first 4 and a second electrode 5 for the application of electric voltage for generating an electric field within one chamber 2. At least two first electrodes 4 of different chambers 3 are conductively coupled and at least one second electrode 5 of said chamber 2 is separately conductively connectable. The invention further concerns a method for manufacturing said container 1 as well as a device for electrically contacting at least one of said containers 1.
US08101400B2 Grass based avian deterrent
The invention relates to uses and methods relating to grass and endophyte combinations to repel avian species from the grass and endophyte combination. In particular, methods are described to select grass and endophyte combinations in order to enhance or maximise the repellent effect. Preferred endophyte and grass combinations are described which are based on the selection methods and include AR4, AR5, AR8 and AR94 (Deposit Nos. V07/029054, V07/029055, V071029056, V07/029057) in Lolium cultivars as well as AR601, AR602, AR603, and AR604 (Deposit Nos. V07/029058, V07/029059, V07/029060, V07/029061) in Festuca cultivars.
US08101398B2 Modified cellulases with increased thermostability, thermophilicity, and alkalophilicity
A modified Family 6 cellulase enzyme comprising a proline residue at position 413 is provided. Genetic constructs and genetically modified microbes comprising DNA sequences encoding the modified Family 6 cellulase are also provided. Family 6 cellulases of the invention display improved thermostability, thermophilicity, alkalophilicity, or a combination thereof, relative to the parent Family 6 cellulases. Such cellulases find use in a variety of applications in industry that require cellulase stability and activities at temperatures, pH values, or both, above that of the native enzyme.
US08101397B2 Methods and compositions for the recombinant biosynthesis of n-alkanes
The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently convert carbon dioxide and light into n-alkanes, and in particular the use of such organisms for the commercial production of n-alkanes and related molecules.
US08101395B2 Halohydrin dehalogenases and related polynucleotides
The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
US08101392B2 Glucoamylase variants
The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
US08101388B2 Method and structure for extracting molecular species
The present invention in one embodiment provides a method for extracting molecular material including providing a probe comprising a penetration portion having a nanoscale surface for penetrating a biological compartment, a receptor present on the penetrating portion of the probe, wherein the receptor has an affinity for a target molecular material from the biological compartment; inserting the probe into the biological compartment, the receptor present on the penetrating portion of the probe engages the target molecular material; and extracting the probe and the target molecular material engaged to the inserting portion of the probe from the biological compartment.
US08101386B2 Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation
The present invention relates to the fields of microbiology and microbial genetics. More specifically, the invention relates to novel bacteria strains and processes employing these strains for the fermentative production of amino acids such as threonine.
US08101379B2 Preparation of low bleeding anticoagulant fusion protein and its use
Provided is an anticoagulant fusion protein comprising oligopeptide recognizable and cleavable by either factor XIa and factor Xa or thrombin and factor Xa. Also provided are the preparation method of the anticoagulant fusion protein and medicinal use thereof.
US08101376B2 Swatch for testing the washing performance of an enzyme
The present invention relates to a swatch comprising a pH-indicator substance and a substrate for an enzyme for testing the washing performance of the enzyme, e.g. an enzyme for use in detergent compositions.
US08101374B2 Oxidative chromogenic compound or salt thereof and production method thereof, and reagent composition and test instrument using the same
It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide an oxidative chromogenic compound or salt thereof represented by the following chemical formula (1): wherein R1 and R2 are each independently a linear or branched alkyl group having 1 to 5 carbon atoms; R3, R4, R5, R6 and R7 are each independently a hydrogen atom, a carboxyl group or a sulfonic acid group, or salt thereof, provided that at least one of R3 to R7 is a carboxyl group or a sulfonic acid group, or salt thereof, and the others are hydrogen atoms, and the production method thereof, and the reagent composition and test instrument using the same.
US08101372B2 Diagnosis and therapy of cancer using SGP28-related molecules
The present invention relates to methods and compositions for the diagnosis and therapy of prostate cancer which utilize isolated polynucleotides corresponding to the human SGP28 gene, proteins encoded by the SGP28 gene and fragments thereof, and antibodies capable of specifically recognizing and binding to SGP28 proteins.
US08101370B2 Genes from the 20q13 amplicon and their uses
The present invention relates to cDNA sequences from a region of amplification on chromosome 20 associated with disease. The sequences can be used in hybridization methods for the identification of chromosomal abnormalities associated with various diseases. The sequences can also be used for treatment of diseases.
US08101369B2 Diagnose device for measuring the ratio of proteins with similar structure
The present invention relates to a diagnostic device for measuring the ratio of similar structural proteins among the proteins secreted in a liquid test sample taken from diagnosis subject. In further detail, the test device according to the present invention comprises detection marker-antibody conjugate recognizing the same site on two or more similar structural proteins and a detection zone in which antibody specifically recognizes each of said proteins via formation of sandwich type complex, wherein said antibodies form a set, and the present Invention relates to a diagnostic device for early diagnosis of polycystic ovary syndrome, abnormal pregnancy, prostatic carcinoma etc. based on determination of the ratio of follicle stimulating hormone and luteinizing hormone in case of polycystic ovary syndrome, the ratio between hCG isomers in case of abnormal pregnancy, and the ratio of prostate-specific antigens (PSA) in case of prostatic carcinoma.
US08101364B2 Fragments of fluorescent proteins for protein fragment complementation assays
The present invention is directed to Protein-fragment Complementation Assays (PCAs) and assay compositions based on fluorescent proteins. The invention provides methods for fragmenting fluorescent proteins and generating mutant fragments with desired spectral characteristics for PCA. The invention encompasses assays and compositions based on fluorescent proteins from the species Aequorea, Anemonia and Anthozoa. In particular, the invention is directed to fragments of mutant fluorescent proteins having improved spectral properties over the wild-type proteins. The invention encompasses fragments of mutant versions of A. Victoria green fluorescent protein (GFP), in particular yellow fluorescent proteins (EYFP and super-EYFP), ‘Venus’, cyan, ‘citrine’, blue, cyan-green, and photoactivatable variants of GFP The invention also encompasses red fluorescent PCAs based on Discosoma red fluorescent protein (RFP PCA) and a kindling fluorescent protein PCA (KFP1 PCA) derived from Anemonia sulcata. Any useful mutation of a fluorescent protein can be engineered into a fragment, generating a wide range of assays useful for drug discovery, target validation, high-throughput screening, high-content screening, pathway mapping, drug mechanism-of-action studies, biosensors, and diagnostics.
US08101360B2 IL-1 gene cluster, insulin resistance and coronary artery disease associated polymorphisms and haplotypes and methods of using same
The invention provides methods and compositions relating to identification and use of genetic information from the IL-1 gene cluster—including the structure and organization of novel IL-1-like genes found within the IL-1 locus as well as polymorphisms and associated haplotypes within these genes. The invention thereby expands the repertoire of useful genetic information available from the IL-1 locus—which contains the previously-identified IL-1α, IL-1β and IL-1RN genes, for predicting IL-1 associated phenotypes (e.g. increased or decreased risks of insulin resistance associated pathologies) and for treating IL-1 haplotype associated insulin resistance associated pathologies.
US08101359B2 Method for determining risk of relapse of breast cancer following tamoxifen adjuvant therapy
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
US08101358B2 Method of profiling gene expression in a subject having disease
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
US08101351B2 Process for typing of HCV isolates
The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of: contacting said sample in which the ribonucleotides or deoxyribonucleotides have been made accessible, if need be, under suitable denaturation, with at least one probe from about 10 to about 40 nucleotides, with said probe being liable to hybridize to a region being in the domain extending from nucleotide at position −291 to nucleotide at position −66 of the 5′ untranslated region of one of the HCV isolates represented by their cDNA sequences, with said numbering of position beginning with the first ATG codon of the open reading frame encoding the HCV polyprotein, or with said probe being complementary to the above-defined probes, detecting the complexes possibly formed between said probe and the nucleotide sequence of the HCV isolate to be identified.
US08101346B2 Identifier and nucleic acid amplification method of verification using the same
There is provided an identification technique that can consistently maintain a set of information specifying a specimen through all the processes from the amplification process to the detection process of a specific sequence. A base sequence incorporating as a set of decodable information an individual code imparted to the specimen is disposed in an amplifiable region to form an identifier; the identifier is amplified together with the specimen and the presence of the identifier in the amplification product is detected; thus, the individual code of the specimen in the amplification product can be recognized, which specimen the amplification product is derived from can be easily identified, and whether or not the amplification has been carried out satisfactorily can also be simultaneously tested.
US08101344B2 Device and method for high-throughput quantification of mRNA from whole blood
Disclosed are a method, device kit, and automated system for simple, reproducible, and high-throughput quantification of mRNA from whole blood. More particularly, the method, device, kit and automated system involve combinations of leukocyte filters attached to oligo(dT)-immobilized multi-well plates.
US08101343B2 Delivery of dsRNA to arthropods
The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.
US08101338B2 Method of forming micro pattern of semiconductor device
The present invention relates to a method of forming a micro pattern of a semiconductor device. According to an aspect of the present invention, a first photoresist layer and a second photoresist layer with different exposure types are formed over a semiconductor substrate on which an etch target layer is formed, performing an exposure process on the second photoresist layer and the first photoresist layer. Second photoresist patterns are formed by developing the second photoresist layer. First photoresist patterns are formed by etching the first photoresist layer using an etch process employing the second photoresist patterns as an etch mask. Auxiliary patterns are formed by developing the first photoresist patterns. The etch target layer is etched by employing the auxiliary patterns.
US08101335B2 Resist composition and patterning process
A copolymer of an alkali-soluble (α-trifluoromethyl)-acrylate and a norbornene derivative is useful as an additive to a resist composition. When processed by immersion lithography, the resist composition exhibits excellent water repellency and water slip and forms a pattern with few development defects.
US08101334B2 Image processing method and image processing apparatus
To provide an image processing method including at least one of recording an image onto a thermoreversible recording medium in which transparency or color tone reversibly changes depending upon temperature, by applying a laser beam with the use of a semiconductor laser device so as to heat the thermoreversible recording medium, and erasing an image recorded on the thermoreversible recording medium, by heating the thermoreversible recording medium, wherein an intensity distribution of the laser beam applied in the image recording step satisfies the relationship represented by Expression 1 shown below, 1.20≦I1/I2≦1.29  Expression 1 where I1 denotes an irradiation intensity of the applied laser beam in a central position of the applied laser beam, and I2 denotes an irradiation intensity of the applied laser beam on a plane corresponding to 95% of the total irradiation energy of the applied laser beam.
US08101333B2 Method for formation of miniaturized pattern and resist substrate treatment solution for use in the method
The present invention provides a method for miniaturizing a pattern without seriously increasing the production cost or impairing the production efficiency. This invention also provides a fine resist pattern and a resist substrate-treating solution used for forming the fine pattern. The pattern formation method comprises a treatment step. In the treatment step, a resist pattern after development is treated with a resist substrate-treating solution containing an amino group-containing, preferably, a tertiary polyamine-containing water-soluble polymer, so as to reduce the effective size of the resist pattern formed by the development. The present invention also relates to a resist pattern formed by that method, and further relates to a treating solution used in the method.
US08101331B2 Method and apparatus of rapid continuous process to produce chemical toner and nano-composite particles
A process for making particles is provided. In embodiments, a suitable process includes a mixing tank for mixing a plurality of particles dispersed within a liquid media and a vane unit for applying a swirling effect to the plurality of droplets received from the mixing tank through a spray nozzle. The vane unit is in operable communication with a spray nozzle for launching a plurality of droplets, the plurality of droplets including different combinations of the plurality of particles. The process further includes a plurality of outlet ports, where each of a first set of outlet ports includes a filter and of the other outlet port is filterless.
US08101330B2 Two component developer and image forming method
A two component developer comprising a toner and a carrier, wherein the toner includes: colored particles; and external additive particles comprising a complex oxide incorporating silicon atoms and at least one of titanium atoms and aluminum atoms, and a surface existing ratio of the silicon atoms (R2) in a surface of the external additive particles being larger than an average existing ratio of the silicon atoms (R1) in an entirety of the external additive particles, and carrier particles comprise magnetic material powder dispersed in a phenol-formaldehyde resin, and have an average of the shape coefficient SF-1 of 1.0 to 12 and an average of the shape coefficient SF-2 of 1.1 to 2.5, and a volume based median diameter of from 10 to 100 μm.
US08101324B2 Photomask manufacturing method, photomask manufacturing apparatus and photomask
A photomask manufacturing method which includes generating data of a main pattern to be transferred onto a substrate, and data of an assist pattern which is arranged adjacent to the main pattern and which assists the transfer of the main pattern without being transferred onto the substrate; performing an optical proximity effect correction to the generated data of the main pattern; correcting shapes of the main pattern and the assist pattern on the basis of a shape change caused at an edge of the main pattern facing the assist pattern by the optical proximity effect correction; and forming a photomask by using the data of the main pattern and of the assist pattern which have been corrected.
US08101322B2 Constant channel cross-section in a PEMFC outlet
A plate for a fuel cell is disclosed, wherein an inlet aperture is disposed at a first end of the plate and an outlet aperture is disposed at a second end of the plate. The plate includes a first side and a second side. The first side of the plate has a flow field formed therein between the inlet aperture and the outlet aperture, the flow field having a plurality of flow channels formed therein, the plurality of flow channels in communication with a plurality of outlet ports formed in the plate. The second side of the plate has a plurality of drainage channels formed therein adjacent the outlet aperture, the plurality of drainage channels in fluid communication with the outlet ports and the outlet aperture, wherein a cross-sectional area occupied by each of the plurality of flow channels is substantially equal to a cross-sectional area occupied by each of the plurality of drainage channels.
US08101320B2 Fuel cell integrated humidification
A device and method to extract water from a moisture-rich fuel cell flowpath to supply other components of a fuel cell system that require water. A water transport unit is integrated into the fuel cell so that the size, weight and complexity of a fuel cell is minimized. In one embodiment, the device includes numerous flowpaths that include an active region and an inactive region. The water transport unit includes a moisture-donating fluid channel and a moisture-accepting fluid channel, where the latter is fluidly connected with a portion of the fuel cell that is in need of humidification. Upon passage of a moisture-donating fluid through the inactive region of the device flowpath, at least some of the water contained therein passes through the water transport unit to a portion of the fuel cell that is in need of humidification.
US08101318B2 Method for fuel cell assembly with springs and pins
A spring loaded direct oxidation fuel cell assembly reduces the effects of precompression relaxation. A near flat spring and a distribution plate form a spring assembly that is disposed between a membrane electrode assembly and one of the current collectors in the fuel cell. The components are assembled into a fuel cell assembly and are precompressed, and a spring yielding process is performed. While precompression is being applied, a set of pins and a plastic frame are insert molded around the fuel cell assembly to hold the components in place. Subsequently, as the precompression relaxes, the spring assembly forces act to maintain an evenly distributed compression on the MEA, thereby compensating for the loss of precompression. A related method of manufacturing a fuel cell assembly is provided.
US08101313B2 Flow field plate module for fuel cell system
A flow field plate module for a fuel cell system includes at least one flow field plate defining a fuel transporting channel thereon. The fuel transporting channel is divided into a middle converging zone having a group of first flow guiding plates arranged therein, and two diverging zones located at two lateral sides of the middle converging zone and each having a group of second flow guiding plates arranged therein. The second flow guiding plates are symmetrically arranged in the two diverging zones and are directed at respective inner end toward a space between two adjacent first flow guiding plates in the middle converging zone to thereby offset from each of the two adjacent first flow guiding plates by a predetermined distance in a fuel flowing direction, so that a fluid path is formed between any two adjacent first and second flow guiding plates.
US08101309B2 Fuel cell system and scavenging method therefor
A fuel cell having an oxygen-containing gas flow field and a fuel gas flow field, an oxygen-containing gas supply apparatus for supplying an oxygen-containing gas to the oxygen-containing gas flow field, a fuel gas supply apparatus for supplying a fuel gas to the fuel gas flow field, a scavenging gas supply apparatus for supplying air as a scavenging gas to the fuel gas flow field, and a controller are provided. The controller includes a voltage detection unit for detecting the voltage of the fuel cell after operation of the fuel cell is stopped and a scavenging control unit for starting scavenging in the fuel gas flow field by the scavenging gas supply apparatus after the detected voltage is decreased temporarily, increased, and decreased again to become a preset voltage or less.
US08101292B2 Magnetic storage media with Ag, Au-containing magnetic layers
A magnetic recording medium having a Au, Ag-containing magnetic layer having Co, Cr, Ag and Au; the magnetic recording layer having Co-containing magnetic grains surrounded by substantially nonmagnetic Cr-containing grain boundaries; wherein said Ag and said Au are substantially immiscible in the Co-containing magnetic grains is disclosed.
US08101285B2 Metallic material for a connecting part and a method of producing the same
A metallic material for a connecting part, having a rectangular wire material of copper or a copper alloy as a base material, and formed at an outermost surface thereof, a copper-tin alloy layer substantially composed of copper and tin, wherein the copper-tin alloy layer of the outermost surface further contains at least one selected from the group consisting of zinc, indium, antimony, gallium, lead, bismuth, cadmium, magnesium, silver, gold, and aluminum, in a total amount of 0.01% or more and 1% or less in terms of mass ratio with respect to the content of the tin.
US08101280B2 Alkali-resistant coating on light metal surfaces
An article which comprises a surface of light metal. The surface is provided with an alkali-resistant protective coat comprising (a) an oxide layer which comprises silicon and boron as a basecoat and (b) an oxide layer which comprises silicon as a vitreous topcoat.
US08101275B2 Device based on nitinol, a process for its production, and its use
The present invention relates to a device comprising a substrate based essentially on nitinol and, arranged thereon at least partially, a covering or a coating based on at least one polyphosphazene derivative having the general formula (I), a process for its production, and the use of the device as an artificial implant, vascular or nonvascular stent, catheter, thrombolectomy or embolectomy catheter, fragmentation spindle or catheter, filter, vascular connector, hernia patch, oral, dental or throat implant or urether.
US08101274B2 Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom
Disclosed herein are glycosylated amphiphilic molecules composed of hydrophobic “tails” and hydrophilic “heads” that self align to form a membrane at the interface of a polar solvent and a non-polar liquid or a solid. The present invention is directed to a solid state membrane, typically a thin film, composed of a non-polar solid material having the hydrophobic “tail” of a glycosylated amphiphilic molecule embedded in or linked to its surface such that the hydrophilic “head” protrudes from the solid surface and presents useful properties to the surrounding environment. A membrane or film in accordance with the present invention is produced when a non-polar liquid, in the presence of a polar solvent and an amphiphilic biological compound, undergoes a transformation from liquid to solid, through thermal, chemical or radiative means, with the resultant effect that the amphiphilic molecule is affixed or “locked” to the surface, more particularly the hydrophobic ends of the amphiphilic compounds are mechanically or chemically linked to or embedded in the non-polar solid. The membrane and micelles produced therefrom remain stable even in the absence of the polar solvent, thereby allowing the hydrophilic components of the amphiphilic compounds to present useful properties at the surface thereof.
US08101273B2 Coating comprising layered structures of diamond like nanocomposite layers and diamond like carbon layers
The invention relates to a coating comprising a number of layered structures, each such layered structure comprising—a first layer comprising a diamond like nanocomposite layer, said first layer comprising carbon, hydrogen, oxygen and silicon; a second layer comprising a diamond like carbon layer. The number of layered structure is higher than 4 and is preferably between 10 and 100. The invention further relates to a method to deposit such a coating.
US08101270B2 Bonding material for honeycomb structure and honeycomb structure utilizing the material
A bonding material for a honeycomb structure comprises inorganic particles in which D90/D10 is from 10 to 500, D10 is 100 μm or less and D90 is 4 μm or more, and the D10 and D90 are the values of 10% diameter and 90% diameter from a smaller particle diameter side, respectively, in volume-based integrated fractions of a particle diameter distribution measurement by a laser diffraction/scattering method.
US08101269B2 Porous fired body and manufacturing method thereof
A porous fired body including a structure that aggregates are bonded by a bonding material, wherein the aggregates include oxide particles having a larger thermal capacity per unit volume than an SiC particle and SiC, the bonding material includes metallic Si, volume ratio of the metallic Si in the whole porous fired body is between 8 and 43% by volume, volume ratio of the particles of the oxide in the whole aggregates is between 14 and 55% by volume, the SiC particles and the oxide particles respectively include one or more particle groups, and an average particle size of each particle group is within a range of between 5 and 100 μm.
US08101267B2 Multilayer polymeric laminates and high strength laminates produced therefrom
The present invention provides for certain multilayer polymeric laminates and high strength laminates produced therefrom. The multilayer polymeric laminates provide improved acoustic barrier properties of the high strength laminates of the present invention.
US08101263B2 Cooling systems using coatings with surface energy gradient
A cooling system comprising a plurality of coolant channels comprising a fluid-impervious surface comprising a base surface, at least one distinct region of the base surface covered by a mixed monolayer, the mixed monolayer comprising a species having a functional group M1 and a species having a functional group M2 where M1 and M2 have different surface energies, the mixed monolayer forming a surface energy gradient within the region and wherein any portions of the surface that border the at least one distinct region have substantially equal surface energies.
US08101261B2 One-dimensional arrays of block copolymer cylinders and applications thereof
Methods for fabricating sublithographic, nanoscale microstructures in one-dimensional arrays utilizing self-assembling block copolymers, and films and devices formed from these methods are provided.
US08101260B2 Flocked metal plate, method of producing flocked metal plate, roofing material and duct for air-conditioning system
It is intended to provide a flocked metal plate, which has a hydrophilic nature and is excellent in water retention property and water absorbing property, and a method of producing the flocked metal plate. A flocked metal plate having a flocked layer, which is formed by implanting short fibers as short fiber bundles in a synthetic resin adhesive layer provided at least one face of a metal plate or a surface treated metal plate, wherein the synthetic resin adhesive layer is made a hydrophilic synthetic resin adhesive layer, the short fibers implanted in the synthetic resin adhesive layer are made hydrophilized short fibers, and the short fibers are implanted in the synthetic resin adhesive layer to give a flocked layer having short fiber bundles at as high density as possible, thereby giving a flocked metal plate carrying a flocked layer having been made a flocked layer which exhibits a hydrophilic nature, water retention property and water absorbing property.
US08101259B2 Composite thermally insulating material
A composite thermally insulating material suitable for use in houses, which can manifest high thermal insulation performance when packed into a restricted cavity between outer and inner walls. The composite is constructed from two sheet-shaped fiber-based thermally insulating materials and a vacuum thermally insulating material incorporated between the fiber-based thermally insulating materials. The region between the fiber-based thermally insulating materials and vacuum thermally insulating material can be secured with adhesive agent.
US08101258B2 High density information storage medium having plasmonic nano device
A high density information storage medium includes a recording layer in which information is stored; a thin metal film placed on the recording layer and having a structure in which nano-apertures having a size of several nanometers to several hundred nanometers are defined at regular intervals; and a protective layer placed on the thin metal film. As light irradiated from above the protective layer passes through the nano-apertures, physical characteristics of the recording layer are changed, whereby information is stored.
US08101253B2 Biodegradable multiphase compositions based on starch
The present invention relates to biodegradable multiphase compositions characterized in that they comprise three phases: (a) a continuous phase composed of a matrix of at least one tough hydrophobic polymer incompatible with the starch; (b) a nanoparticulate dispersed starch phase with mean dimensions of less than 0.3 μm, (c) a further dispersed phase of at least one rigid and fragile polymer with modulus greater than 1000 MPa. Such compositions having a Modulus greater than 300 MPa and a substantial isotropy in the two longitudinal and transverse directions in relation to tear propagation.
US08101250B2 Coated paper for sheet-fed offset printing
The specification pertains to a single or multiple coated printing sheet in particular but not exclusively for sheet-fed offset printing with an image receptive coating layer on a paper substrate. Unexpectedly short converting times and times until reprinting can be achieved by choosing a coating, in which the image receptive coating layer comprises a top layer and/or at least one second layer below said top layer, said top and/or second layer comprising a pigment part, wherein this pigment part is composed of 1-95 preferably of 80-95 parts in dry weight of a fine particulate carbonate and/or of a fine particulate kaolin or clay and 1-100, preferably 6 to 25 parts in dry weight of a fine particulate silica, and a binder part, wherein this binder part is composed of 5-20 parts in dry weight of binder and less than 4 parts in dry weight of additives. Furthermore methods for making such a printing sheet and uses of such a printing sheet are disclosed.
US08101249B2 Retardation substrate, method of manufacturing the same, and liquid crystal display
A retardation layer that includes regions causing different retardations can be manufactured easily. A retardation substrate includes a substrate and a solidified liquid crystal layer supported by the substrate. The solidified liquid crystal layer includes first to third regions. The first to third regions re arranged on the substrate and different in degree of orientation of mesogens.
US08101242B2 Method of imparting corrosion resistance to a substrate surface, and coated substrates prepared thereby
The disclosure provides methods and materials for imparting corrosion resistance to a substrate, as well as the corrosion-resistant substrates prepared accordingly. Compositions and methods include nonpyrolyzed, silicon-based polymer coatings prepared on substrates. The prepared coatings are highly stable and resistant to corrosion. The invention finds utility, for example, in the fields of surface and coating chemistry.
US08101240B2 Release coating and process
A release coating having improved stability under aging conditions of heat and humidity is described whose release force can be altered by varying the amount of multi-lobe emulsion polymers relative to release agent.
US08101239B1 Apparatus and method for producing an intermediate fibrous product
A continuous process for achieving specific levels of fire retardant properties for either natural fibers or synthetic fibers. Selected fibers are mixed and opened to be formed into a web that is continuously weighed and transported to a spray station to be sprayed by a selected fire retardant solution. The sprayed web is compressed between calendar rolls and transported to a dryer; the dried web is blended to form a selected fiber having a predetermined fire retardant characteristic to meet regulatory standards. An intermediate product results from the use of the process.
US08101231B2 Processes for forming photovoltaic conductive features from multiple inks
Photovoltaic conductive features and processes for forming photovoltaic conductive features are described. The process comprises (a) providing a substrate comprising a passivation layer disposed on a silicon layer; (b) depositing a surface modifying material onto at least a portion of the passivation layer; (c) depositing a composition comprising at least one of metallic nanoparticles comprising a metal or a metal precursor to the metal onto at least a portion of the substrate; and (d) heating the composition such that it forms at least a portion of a photovoltaic conductive feature in electrical contact with the silicon layer, wherein at least one of the composition or the surface modifying material etches a region of the passivation layer. When the surface modifying material is a UV-curable material, the process comprises the additional step of curing the UV-curable material.
US08101230B2 Method for producing electronic device and coating solutions suitable for the production method
It is intended to provide a method for producing an electronic device having a multilayer structure by a coating method, and a coating solution suitable for the production method. The present invention provides a method for producing an electronic device having at least two or more stacked layers containing organic matter, comprising a first step of applying a coating solution containing organic matter and a metal and/or a metal oxide onto a substrate either directly or via an additional layer to form a mixed layer, and a second step of directly applying a solution containing organic matter onto the mixed layer formed in the first step to form an organic layer. According to this method, an electronic device having a multilayer structure can be produced easily by a convenient coating method.
US08101227B2 Composition and methods of making frozen infant and toddler food
The present invention is aimed to retain the taste and texture of infant and toddler food products that have been frozen. By employing a slow-churning freezing process, the frozen infant and toddler products are lighter in color, smoother and creamier in texture and possess a better taste profile. The invention further comprises methods of making and using such products.
US08101219B2 Apparatus for preparing egg products in a microwave oven
An apparatus and method is provided for preparing liquid egg products, for example pure egg whites, whole eggs and egg products either alone or mixed with spices, vegetables or other ingredients, in a microwave oven. The container for preparing the liquid egg products is relatively inexpensive and disposable. In another embodiment of the present invention, a method is provided for preparing liquid egg products in a disposable, microwavable container in which the liquid egg product expands while cooking and partially removes the lid of the container to create a delicious meal of properly cooked, fresh egg product, that are ready for consumption.
US08101212B2 Bioactive botanical cosmetic compositions and processes for their production
The present invention is directed to bioactive botanical cosmetic compositions derived from membrane and cell serum fractions of plant cell juice. The present invention also relates to the methods for preparing these bioactive botanical cosmetic compositions and the uses of these compositions in various cosmetic formulations and as topical skin cosmetic applications.
US08101211B2 Compositions for retarding skin aging
A composition for retarding skin aging which contains an edible herb medicine or medicines round in Taiwan, in particular a plant extract or extracts having melanin formation-unhibiting, elastase-inhibiting, hyaluronidase-inhibiting, active oxygen-eliminating and/or radical-capturing type antioxidant activities, and a medicinally acceptable base and/or additives for external dermal application. The composition is useful in promoting skin whitening effects, maintaining the tension and elasticity of the skin, facilitating skin moistening and providing the skin with anti-inflammatory and/or anti-allergic properties.
US08101210B2 Use of carbon dioxide supplying means for muscle strengthening and method of increasing cattle meat thereby
Use of a carbon dioxide-supplying means for muscle strengthening makes it possible conveniently to strengthen a target muscle within a short period of time merely by allowing the target site to absorb carbon dioxide without loading any mechanical burden on the target muscle. By loading a mechanical burden on the target muscle, the muscle strengthening effect can be further enhanced and an additional effect of promoting the recovery from muscle fatigue can be achieved owing to the mechanical burden. By using the carbon dioxide-supplying means for muscle strengthening as described above, it is also possible to increase cattle meat.
US08101209B2 Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
The invention relates to a microparticulate system for the delayed and controlled release of active principles (AP) whose absorption window in vivo is essentially limited to the upper parts of the gastrointestinal tract, this system being intended for oral administration. The object of the invention is to provide a system ensuring that the AP is released with certainty by means of a dual mechanism of “time-dependent” and “pH-dependent” release. To achieve this object, the invention proposes a multimicrocapsular oral galenical form which is designed so as to guarantee therapeutic efficacy, and in which the release of the AP is governed by a dual release triggering mechanism that is “time-triggering” and “pH-triggering”. This system comprises of microcapsules (200 to 600 μm) comprising a core of AP coated with a film (maximum 40% by weight) comprising a hydrophilic polymer A (Eudragit® L) and a hydrophobic compound B (vegetable wax, melting point=40-90° C.), B/A being between 0.2 and 1.5. These microcapsules have a dissolution behavior in vitro such that, at a constant pH of 1.4, a latency phase of between 1 and 5 hours is observed, followed by a release of the AP, and such that the change from pH 1.4 to pH 6.8 results in a release of the AP without a latency period in vitro.
US08101208B2 Sensate compositions and delivery systems therefor
The present invention includes compositions for imparting a controlled-release sensation to the oral receptor areas of a user. The oral, controlled-release compositions include a sensate and a hydrated or swollen food-grade polymer which forms a matrix with the sensate. Sensates may include warming, cooling and/or tingling agents. Also included are oral delivery systems for the compositions, methods for preparing same, and methods for imparting and sustaining a desired sensation in the mouth and upper portion of the gastrointestinal tract of the user.
US08101207B2 Composition containing medicine extremely slightly soluble in water and method for preparation thereof
A composition containing a very low water-soluble drug, which composition is produced by treating, with a supercritical or subcritical carbon dioxide fluid, a mixture containing a very low water-soluble drug and a porous material (exclusive of a porous silica material characterized in that the material has an average pore diameter of 1 to 20 nm, the total pore volume of the material that have a diameter falling within a range of ±40% of the average pore diameter account for 60% or more the volume of all the pores of the material, and, when subjected to X-ray diffractometry, the material exhibits one or more peaks at a diffraction angle (2θ) corresponding to d of 1 nm or more); and a method for producing the composition.The very-low-water-soluble-drug-containing composition of the present invention ensures improved dissolution of the very low water-soluble drug.
US08101204B2 Hard capsule composition and method of use
A method for making clear hard vegetarian gelatin free two piece capsules by creating the first phase of the biphasic system using seaweed extract, gellan gum, metallic element, maltol extract, seaweed extract and water. A filler is created for the first phase of the biphasic network by blending water, galactomannan extract, and cellulose. The filler is then mixed into the system forming a biphasic system, a first pin is then dripped into the blend and then a second pin is then dripped into the blend. Blowing hot air on the dipped pins, which then blows away water on the outer surface of the dipped pins to bond and lock moisture to the cellulose. A large diameter capsule piece is removed from the first pin and a small diameter capsule piece is removed from the second pin, wherein each capsule piece has an outer surface which is mechanically and dimensionally stable.
US08101202B2 Gentle process for conversion of cystine in keratin-containing materials to lanthionine
Useful materials are produced from keratin containing raw materials by a process that includes gentle lanthionization of cystine disulfide bonds. Hydratable materials are produced for use in medical and cosmetic applications.
US08101201B2 Compositions comprising dietary fat complexer and methods for their use
This invention relates to fat containing consumable food products comprising α-cyclodextrin. The food products have reduced levels of bioavailable fat but have substantially the same fat, cholesterol and caloric content as a like food without α-cyclodextrin. The invention also relates to methods for reducing the bioavailability of fats in fat containing food products without reducing caloric intake as determined by bomb calorimetry and to methods for increasing high density lipoproteins in a subject and reducing or controlling weight by administering the food products of this invention.
US08101200B2 Targeted therapeutic agent release devices and methods of making and using the same
Generally, the present invention provides devices and methods for delivering high, efficacious concentrations of therapeutic agents, i.e., medicaments such as drugs, antibiotics, etc., to specific sites in a patient's body, such as tumors and infected lesions. In one aspect of the present invention there are provided devices to accomplish the aforesaid delivery of therapeutic agents and methods to accomplish the delivery by positioning a device in the body using minimally invasive techniques such as, for example, catheterization or via trochar. The devices may contain a carrier substrate and a coating on the substrate. The carrier substrate provides structural integrity to the device and the coating thereon contains at least one layer of polymeric material containing one or more medicaments. Optionally, there may be a non-medicated binder coat between the carrier substrate and the medicated polymer layer. The medicated polymer layer may contain a hydrophilic/hydrophobic polymer composition.
US08101199B2 Des-methyl-tocopherol therapy for restenosis prevention
A stent is provided in combination with delivery of a tocopherol agent, and in particular a des-methyl tocopherol agent, and further beneficially a gamma-tocopherol agent, so as to reduce restenosis along the vessel or other lumenal wall where the stent is implanted. In particular applications, the stent is an endolumenal stent, and more specific beneficial applications is an endovascular stent, and the gamma-tocopherol elutes from a coating or carrier coupled with the stent. Certain combinations are provided with the des-methyl-tocopherol or phytyl substituted chromanol, e.g. gamma-tocopherol, combined with an additional agent such as an anti-restenosis agent, e.g. sirolimus, tacrolimus, everolimus, or paclitaxel, in order to provide synergistic benefit to tissues along the stented or recanalized regions. Other forms of tocopherol or tocotrienol, or other phytyl substituted chromanols, and other compounds such as palm oil, are also contemplated, for use to treat restenosis.
US08101197B2 Forming coils
Coils, such as embolic coils, can include a substrate; and a porous material supported by the substrate. Related methods, devices, and compositions, can include: injecting a material into a container containing the coil; and forming the material into a coating that is supported by the coil and/or contacting the coil with a composition comprising a first polymer and a gelling precursor; and forming the composition into a coating that is supported by the coil.
US08101196B2 Polysaccharide biomaterials and methods of use thereof
The invention includes a medical hydrogel made from polymerized polysaccharide macromers. The macromers are preferably polysaccharides decorated with polymerizable groups, for example, methacrylates. The macromers may also be made into polymers of at least two macromers polymerized together. These polymers are preferably multi-armed or high-molecular weight and used for medical uses, for example, making coatings on medical devices. Macromers of N-vinylpyrrolidone are also disclosed herein.
US08101190B2 Method for diagnosing staphylococcal infections
The present invention relates to a method for determining if an individual is infected by a staphylococcus bacterium, comprising: determining if antibodies directed against at least 2 proteins comprising a sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 4, and SEQ ID NO: 6, are present in a biological sample of the individual, and deducing therefrom that the individual is infected by a staphylococcus bacterium.
US08101188B2 Methods for the modulation of neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections
Described is the modulation of the neovascularization and/or growth of collateral arteries and/or other arteries from preexisting arteriolar connections. Methods are provided for enhancing neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections comprising contacting organs, tissue or cells with a colony stimulating factor (CSF) or a nucleic acid molecule encoding said CSF. Furthermore, the use of a CSF or a nucleic acid molecule encoding said CSF for the preparation of pharmaceutical compositions for enhancing neovascularization and/or collateral growth of collateral arteries and/or other arteries from preexisting arteriolar connections is described. Also provided are methods for the treatment of tumors comprising contacting an organ, tissue or cells with an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through the inhibition of the biological activity of CSFs. Described is further the use of an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through inhibition of the biological activity of CSFs for the preparation of pharmaceutical compositions for the treatment of tumors.
US08101186B2 Peptides that block the binding of IgG to FcRn
The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates to methods of using and methods of making the peptides of the invention.
US08101180B2 Anti-IGF-IR and/or anti-insulin/IGF-I hybrid receptors antibodies and uses thereof
The present invention relates to novel antibodies capable of binding specifically to the human insulin-like growth factor I receptor (IGF-IR) and/or the insulin/IGF-I hybrid receptor (hybrid-R) and/or capable of specifically inhibiting the tyrosine kinase activity of said IGF-IR and/or hybrid-R, especially monoclonal antibodies of murine, chimeric and humanized origin, as well as the amino acid and nucleic acid sequences coding for these antibodies. The invention likewise comprises the use of these antibodies as a medicament for the prophylactic and/or therapeutic treatment of cancers overexpressing IGF-IR and/or hybrid-R or any pathology connected with the overexpression of said receptor as well as in processes or kits for diagnosis of illnesses connected with the overexpression of the IGF-IR and/or hybrid-R. The invention finally comprises products and/or compositions comprising such antibodies in combination with anti-EGFR antibodies and/or compounds and/or anti-cancer agents or agents conjugated with toxins and their use for the prevention and/or the treatment of certain cancers.
US08101179B2 Anti-CD20 monoclonal antibody
A murine anti-CD20 monoclonal antibody having cell growth inhibitory activities is disclosed. Cell growth inhibitory activities include apoptosis against human CD20 antigen expressing cells in culture of the CD20 antigen expressing cells without effector cells. The anti-CD20 monoclonal antibody is incorporated into chimeric anti-CD20 monoclonal antibodies in which the amino acid sequences of the variable regions of the anti-CD20 monoclonal antibody and the amino acid sequences of the constant regions of human immunoglobulin are fused. Also a humanized anti-CD20 monoclonal antibody is described which includes all of the variable region CDRs of the H chain of the anti-CD20 monoclonal antibody and all of the variable region CDRs of the L chain of the anti-CD20 monoclonal antibody and an amino acid sequence of human immunoglobulin. A nucleotide sequence encoding the amino acid sequence of the chimeric or humanized anti-CD20 monoclonal antibody can be expressed in mammalian cells.
US08101178B2 Antibodies directed to tumor necrosis factor and uses thereof
Antibodies directed to the antigen TNFα and uses of such antibodies. In particular, fully human monoclonal antibodies directed to the antigen TNFα. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies.
US08101177B2 Anti-VEGF antibodies
Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naive libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
US08101174B2 Pharmaceutical compositions for treating arthritis and inflammatory disease
The biological effects of the cytokine TNF are mediated by binding to receptors on the surface of cells. This disclosure describes new proteins and polynucleotides that promote enzymatic cleavage and release of TNF receptors. Also provided are methods for identifying additional compounds that influence TNF receptor shedding. As the active ingredient in a pharmaceutical composition, the products of this invention increase or decrease TNF signal transduction, thereby alleviating the pathology of disease.
US08101172B2 Solenopsis invicta virus
A Unique Solenopsis invicta virus (SINV 3) has been identified and its genome sequenced. Oligonucleotide primers have been developed using the isolated nucleic acid sequences of the SINV 3. The virus is used as a biocontrol agent for control of fire ants.
US08101170B2 Probiotic health or fitness promoting human or animal foodstuff and/or drinking water additive and use thereof
The invention relates to a probiotic health or fitness promoting human or animal foodstuff and/or drinking water additive, comprising a mixture of microorganisms, selected from the group Enterococcus faecium, DSM 16211, Lactobacillus reuteri, DSM 16350, Lactobacillus salivarius ssp. salivarius, DSM 16351, Pediococcus acidilactici, DSM 16210, Bifidobacterium animalis and DSM 16284. The invention further relates to a use of the human or animal foodstuff and/or drinking water additive, in particular for prevention of the harmful effect of a number of undesirable germs in the digestive system of animals and/or domestic birds.
US08101167B2 Conditioned medium and uses thereof
The invention relates to compositions containing an agent that has an irritant side effect and a conditioned cell culture medium and/or of an extract thereof, for use, e.g., in the treatment of signs of inflammation and/or of immune disorders, the medium being obtainable by contact with at least one culture of digestive tract cells and at least one probiotic microorganisms. Methods of use.
US08101161B2 Method of enhancing hair growth
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatment.
US08101158B1 Methods for treating cerebrovascular disease comprising administering an agent that inhibits prokineticin receptor activity
The present invention relates to a method of identifying agents that modulate prokineticin receptors, particularly, in the brain. Such agents are useful in the treatment of cerebrovascular diseases, including cerebral ischemia, cerebral hemorrhage, ischemic stroke, hemorrhagic stroke, and ischemic reperfusion injury. Additionally, such agents are useful to treat seizure disorders, such as epilepsy.
US08101156B2 Methods of manufacturing copolymers with zwitterionic moieties and dihydroxyphenyl moieties and use of same
Copolymers are manufactured to include a zwitterionic monomer (e.g., methacryloyloxyethyl phosphorylcholine monomer), a dihydroxyphenyl derivatized monomer, and optionally one or more additional monomers. The dihydroxyphenyl derivatized monomer gives the copolymers excellent adhesion properties. Optional monomers include a cationic amino monomer, a hydrocarbon monomer, and/or a hydrophilic monomer. The copolymers are biocompatible and can be used with medical devices.
US08101152B1 Sonochemical synthesis of titanium-containing oxides
A titanium halide, preferably titanium tetrachloride, is reacted with suitable reductant, preferably an alkali metal or alkaline earth metal, under ultrasonic excitation in a liquid reaction medium to form nanometer size particles of titanium which may incorporate unreacted reductant. The nanosized titanium particles may be a precursor for nanosized titanium oxide which is formed by oxidizing the titanium, preferably with a low molecular weight alcohol. When the titanium particles incorporate unreacted reductant the oxidation reaction will yield nanometer sized titanates. The nanosized particles, whether titanium oxide or titanates may be extracted by first filtering them from the reaction medium, followed by washing with water to remove any water-soluble reaction products followed by spray drying.
US08101149B1 Form of carbon
C60 and C70 carbon atom compounds are prepared by evaporating graphite in an inert quenching gas. The vapor of carbon is collected and is selectively extracted with an organic non-polar solvent.
US08101146B2 Catalysts for the reduction of ammonia emission from rich-burn exhaust
A system for reducing ammonia (NH3) emissions includes (a) a first component comprising a first substrate containing a three-way catalyst, wherein the first component is disposed upstream of a second component comprising a second substrate containing an ammonia oxidation catalyst, wherein said ammonia oxidation catalyst comprises a small pore molecular sieve supporting at least one transition metal; and (b) an oxygen-containing gas input disposed between the components. For example, a CHA Framework Type small pore molecular sieve may be used. A method for reducing NH3 emission includes introducing an oxygen-containing gas into a gas stream to produce an oxygenated gas stream; and exposing the oxygenated gas stream to an NH3 oxidation catalyst to selectively oxidize at least a portion of the NH3 to N2.
US08101145B1 Exhaust treatment system and method of operation
An exhaust treatment system is provided. Method of increasing activation of NOx reduction catalyst using two or more reductant is discussed. The exhaust treatment system includes an exhaust source, a reductant source, a nitrogen oxide (NOx) reduction catalyst, a sensor, and a controller. The reductant source includes a first reductant and second reductant, and is disposed to inject a reductant stream into an exhaust stream from the exhaust source. The NOx catalyst is disposed to receive both the exhaust stream and reductant stream. The sensor is disposed to sense a system parameter related to carbon loading of the catalyst and produce a signal corresponding to the system parameter. The controller is disposed to receive the signal and to control dosing of the reductant stream based at least in part on the signal.
US08101142B2 Process and plant
A reactor system, plant and a process for the production of methanol from synthesis gas is described in which the reactor system comprises: (a) a first reactor adapted to be maintained under methanol synthesis conditions having inlet means for supply of synthesis gas and outlet means for recovery of a first methanol-containing stream, said first reactor being charged with a first volume of a methanol synthesis catalyst through which the synthesis gas flows and on which in use, partial conversion of the synthesis gas to a product gas mixture comprising methanol and un-reacted synthesis gas will occur adiabatically; and (b) a second reactor adapted to be maintained under methanol synthesis conditions having inlet means for supply of the gaseous first methanol-containing stream, outlet means for recovery of a second methanol-containing stream and cooling means, said second reactor being charged with a second volume of a methanol synthesis catalyst through which the gaseous first methanol-containing stream flows and on which, in use, further conversion of the synthesis gas to a product gas mixture comprising methanol will occur.
US08101140B2 Structured catalyst bed and method for conversion of feed materials to chemical products and liquid fuels
The present invention is a structured monolith reactor and method that provides for controlled Fischer-Tropsch (FT) synthesis. The invention controls mass transport limitations leading to higher CO conversion and lower methane selectivity. Over 95 wt % of the total product liquid hydrocarbons obtained from the monolithic catalyst are in the carbon range of C5-C18. The reactor controls readsorption of olefins leading to desired products with a preselected chain length distribution and enhanced overall reaction rate. And, liquid product analysis shows readsorption of olefins is reduced, achieving a narrower FT product distribution.
US08101137B2 Analysis instrument
An analysis instrument for processing a microfluidic device, having sample storage means, a microfluidic device holder, sample loading means for loading sample into a microfluidic device disposed in the holder, processing means for enabling a reaction in a microfluidic device, and detection means for detecting and/or measuring the reaction is disclosed. The microfluidic device holder is adapted to hold the microfluidic device including a tape in position for processing and/or detection. A microfluidic processing device is also disclosed which includes a reaction chamber, and a sample loading chamber into which a sample is injectable. The reaction chamber is operatively connected to the sample loading chamber. A cover extends across at least part of the sample loading chamber. The cover and the reaction chamber include pierceable material and are separated by an overspill cavity configured to accept any overspill of an injected sample. A kit is also disclosed which has the analysis instrument and the microfluidic processing device as described above.
US08101136B2 Kit for estimation of chemical oxygen demand
The present invention relates to a rapid method for estimation of Chemical Oxygen Demand (COD) of water, COD is an important parameter for determining the extent of pollution in water bodies, the basic principle of COD estimation is not much different from prior art but the time taken is reduced considerably and the results are equally sensitive and reproducible as other methods and the method used to generate data on the performance of effluent treatment plants in remote areas or rural areas, it also provide regular and sequential information on the quality of effluent generated by food processing industries.
US08101134B2 Sterilization wrap with additional strength sheet
A sterilization wrap is provided. The sterilization wrap includes a first sheet that is configured for providing a barrier to prevent at least some bacteria from passing therethrough while allowing sterilization gas to pass therethrough. A second sheet is attached to the first sheet. The second sheet is located on the first sheet so that a perimeter of the second sheet is contained entirely within a perimeter of the first sheet.
US08101133B2 Radial flow reactor
A radial flow reactor is disclosed for use in gas purification, separation or reaction processes and most suitably used in prepurification processes. The reactor has two concentric internal baskets which are rigidly supported at both the top and bottom ends of the reactor. The reactor has a removable section in the inner basket to accommodate rotating arms to dense load one or more layers of active materials between the concentric baskets.
US08101132B2 Mixing apparatus
To provide a mixing device capable of effectively mixing stock oil with a catalyst, while increasing the amount of throughput, the relations of 8.0≧Q×(W/D)/(u1+u2), Q=300 to 2000 [kg/m2s], W/D=0.2 to 0.5, u1=5 to 300 [m/s], and u2=5 to 300 [m/s] are satisfied when a mass flow per unit area of a moving bed is Q [kg/nes], the difference between an outer diameter and an inner diameter of the moving bed is W [m], an inner diameter of a reaction tube is D [m], a linear velocity of a horizontal component of the stock oil at a jet orifice of the internal stock oil injection nozzle u1 [m/s], and a linear velocity of a horizontal component of the stock oil at a jet orifice of the external stock oil injection nozzle u2 [m/s].
US08101126B2 Sensor release mechanism for a meter
A sensor-dispensing instrument (10) adapted to handle a sensor pack containing a plurality of sensors and to perform a test using one of the sensors. The sensor-dispensing instrument includes an outer housing (12) and a mechanical mechanism contained therein for rotating the sensor pack and ejecting one of the sensors from the sensor pack and through a sensor slot on the housing. The sensor-dispensing instrument also includes a sensor actuator to engage with a sensor disposed in the sensor slot, and a sensor release (66) that is movable to disengage the sensor actuator from the sensor disposed in the sensor slot and permit the discharge of the sensor the sensor release additionally activating a sensor release mechanism that has a sensor release aid arm, a mounting block, and a pivot pin that connects the sensor release aid arm to the mounting block, wherein the sensor release aid arm is adapted to contact the sensor disposed in the sensor slot to assist removal of the sensor from the sensor slot.
US08101125B2 Reducing corrosion in a turbomachine
A method and system for reducing corrosion in a turbomachine. The method may include providing a process gas to a condenser, wherein the process gas contains a condensate having a pH level that is acidic. The condenser may be configured to remove at least a portion of the condensate from the process gas. Any condensate that is not removed is a remaining condensate. The method may further include increasing the pH level of the remaining condensate to above about 4 by mixing the process gas and the remaining condensate with an amount of pH modifier to form a mixture, and directing the mixture to a compressor coupled to the condenser, wherein the compressor is configured to compress the mixture.
US08101122B2 NiCrMoCb alloy with improved mechanical properties
The invention includes a turbine cover bucket of an alloy including carbon at less than approximately 0.04 weight percent, manganese at approximately 0.0-0.2 weight percent, silicon at approximately 0.0-0.25 weight percent, phosphorus at approximately 0.0-0.015 weight percent, sulfur at approximately 0.0-0.015 weight percent, chromium from approximately 20.0-23.0 weight percent, molybdenum from approximately 8.5-9.5 weight percent, niobium from approximately 3.25-4 weight percent, tantalum at approximately 0.0-0.05 weight percent, titanium from approximately 0.2-0.4 weight percent, aluminum from approximately 0.15-0.3 weight percent, iron from approximately 3.0-4.5 weight percent, and the remainder being nickel. The alloy is heat treated at 538° C. to 760° C. for up to 100 hours. A method of manufacturing the turbine bucket cover is also provided.
US08101121B2 Hydrogen absorbing alloy for alkaline storage battery
A hydrogen absorbing alloy represented by the formula Ln1−xMgxNiy−aAla (where Ln is at least one element selected from rare earth elements, 0.05≦x<0.20, 2.8≦y≦3.9 and 0.10≦a≦0.25) which is used for an alkaline storage battery.
US08101119B2 Electromagnetic stirrer
An object is to provide an electromagnetic stirrer that can provide an excellent stirring force more than before. An electromagnetic stirrer has a vertical electromagnetic field generating coil (1) vertically and circumferentially provided on the outer side of a container (5), and a rotational electromagnetic field generating coil (2) provided on the outer side of the vertical electromagnetic field generating coil (1), in which an iron core (3) is inserted between the vertical electromagnetic field generating coils (1) and between the rotational electromagnetic field generating coils (2), the iron core (3) being formed of a magnetic material with magnetic isotropy and having comb teeth 3a extended to the inner surface of the vertical electromagnetic field generating coil (1).
US08101118B2 Countercurrent direct-heating-type heat exchanger
The countercurrent direct-heating-type heat exchanger that is able to suppress drift in the case when a fluid to be heated is supplied. The heat exchanger is equipped with a feed pipe, a feed nozzle, ring-like straightening plates and umbrella-type dispersing plates of the above fluid to be heated, characterized in that the above feed nozzle has the shape of a pipe having a circular cross section and the dimension satisfying the following formula (1) and formula (2): Ln/Dn≧1  Formula (1) wherein, Ln indicates the length of the feed nozzle; and Dn indicates the inside diameter of the feed nozzle; and 1.5≦Sp/Sn≦2.0  Formula (2) wherein, Sp indicates the inner cross-sectional area of the feed pipe; and Sn indicates the inner cross-sectional area of the feed nozzle.
US08101117B2 Controlled gas pore formers in extruded ware
The present invention provides compositions and methods for producing porous ceramic articles. The compositions and methods comprise a ceramic precursor batch comprising an organic peroxide pore forming agent where the pore forming agent is an organo-adduct of hydrogen peroxide and an organic compound or an organic peroxide of the general formula R—O—O—R′. The organic peroxide pore forming agent is stable during extrusion and other methods for forming a green body and does not decompose until the green body is dried.
US08101114B2 Particle based molding
Various apparatuses, arrangements, and methods are provided for creating various structures including microstructures. In one embodiment, a method for creating a microstructure is provided comprising packing a plurality of particles into a micromold, and then applying energy to the particles in the micromold. As a result of the application of energy, a microstructure is formed in the micromold out of the particles. Thereafter, the microstructure is removed from the micromold.
US08101113B2 Molding apparatus for producing dry cast products having textured side surfaces
An apparatus for molding dry cast products having a textured side surface is disclosed. The apparatus comprises an open compartment for receiving a dry concrete mixture and a plurality of walls laterally enclosing the compartment. At least one of the walls has a multilevel surface with a plurality of sections in an overhanging relationship with each other and transitional curvilinear steps bridging adjacent one of the sections to impart a textured side surface resembling a natural rockface and allowing stripping of the dry cast products from an open bottom side of the compartment.
US08101110B2 Method for jointing rubbery-core-inserted braid
A method for jointing a rubbery-core-inserted braid is provided. In the method, a mold made of a pair of templates is prepared, wherein the templates may be closed in such a manner that trenches can constitute a through hole into which the braid is fittable. The method includes a step of fitting an end of the braid into the trench in one of the templates, while fitting the other end of the braid into the trench, thereby approaching both the ends of the braids each other, a step of interposing a thermoplastic resin between both the ends, and a step of heating and melting the thermoplastic resin in a state where the mold is closed, causing the melted resin to penetrate into the ends of the braids, and solidifying the melted resin, thereby jointing the ends of the braids to each other.
US08101109B2 Solution casting process
Solution casting of polymer film (76, 102) is provided. A dope (22, 115-117) containing a polymer of cellulose triacetate and solvent is cast on a casting support band (34, 121) which moves, to form a cast film (69, 122), and then the cast film is stripped from the casting support band and dried, to produce the polymer film. In the solution casting, the cast film is cooled shortly before stripping the cast film from the casting support band. Preferably, a cooling temperature to which the cast film is cooled is set lower than 6 deg. C. The cast film is cooled within a predetermined cooling region, disposed to start at a stripping point for the cast film, and to extend upstream therefrom with a length equal to or less than 25% of the length of the casting support band. The cast film is blown by cooling gas caused to flow for cooling.
US08101104B2 Process of making a stent
According to an aspect of the present invention, a stent is provided, which contains at least one filament that has a longitudinal axis and comprises a bioabsorbable polymeric material. Polymer molecules within the bioabsorbable polymeric material are provided with a helical orientation which is aligned with respect to the longitudinal axis of the filament. The stent is at least partially bioabsorbed by a patient upon implantation or insertion of the stent into the patient.
US08101103B2 Earbud and method of manufacture
An earbud (10) for carrying sound from a source (16) to a person's ear canal, includes a soft foam body (20) and a sleeve (26) of stiffer material lying within the body. The body is molded around the sleeve and is chemically bonded to the sleeve without an adhesive between them. The earbud is molded around the sleeve by placing the sleeve on a mandrel pin (42) within a mold cavity (32), placing foamable material in the mold and closing the mold. The mold has shoulders with one mold shoulder (52) that abuts one end (46) of the sleeve and another mold shoulder (60) that lies within 0.1 millimeter of the other sleeve end (62), to prevent foaming material from leaking into the space (64) between the mandrel pin and the sleeve passage.
US08101102B2 Method for improving the resistance of fumigant sorption in an expandable polymer produce container and a related container
A method for improving the resistance of fumigant sorption in a produce container made of expandable polystyrene particles in a fumigation process, and related produce container. Expandable polystyrene particles having a density ranging from 40.0 to 32.0 pounds per cubic foot and a blowing agent amount ranging from 2.5 to 7.5 weight percent are pre-expanded to form pre-expanded particles having a core bulk density ranging from 12.5 to 2.0 pounds per cubic foot, and a skin density ranging between 40.0 and 32.0 pounds per cubic foot and a thickness ranging from 0.1 to 2 microns. These pre-expanded particles are injected into a mold to form a produce container having a wall thickness ranging from 0.25 to 2.0 inches.
US08101101B2 Methods for improving the resistance of fumigant sorption in a produce container and a related produce containers
Methods for improving the resistance of fumigant sorption in produce containers made from expandable polystyrene particles in a fumigation process, and related produce containers. An embodiment involves pre-expanding the expandable polystyrene particles to form pre-expanded particles; applying a coating comprised of a chemical selected from the group consisting of mineral oil, polyethylene wax, ethylene vinyl alcohol copolymer, and polyethylene glycol to the pre-expanded particles and in amount of 0.05 to 5.0 parts per hundred; and forming the container from the pre-expanded particles. A further embodiment involves applying the chemical coating to the expandable particles; pre-expanding the expandable polystyrene particles to form pre-expanded particles; and forming the containers from the pre-expanded particles. Other methods involve increasing the cell size of the expandable particles used to form the produce container.
US08101098B2 Additive comprising azomethine compounds
The present invention relates to a mixture of an oligomeric, blocked aminosilane (azomethine structure) and a monomeric, blocked, primary amine (azomethine structure). This mixture is suitable in particular as a curing agent, crosslinker and adhesion promoter.
US08101097B2 Printable compositions containing silver nanoparticles, processes for producing electrically conductive coatings using the same, and coatings prepared thereby
Printable compositions comprising: (a) 5 to 40 parts by weight of silver nanoparticles having a maximum effective diameter of 150 nm, as determined by laser correlation spectroscopy; (b) 50 to 99.5 parts by weight of water; (c) 0.01 to 15 parts by weight of a dispersing agent; (d) 0.5 to 5 parts by weight of a film former; and (g) 30 to 70 parts by weight of metal particles having a maximum effective diameter of 10 μm, as determined by laser correlation spectroscopy; wherein the printable composition has a viscosity of at least 1 Pa·s; processes for producing electrically conductive coatings using such compositions and electrically conductive coatings prepared thereby.
US08101093B2 Chemical-mechanical polishing composition and method for using the same
The invention provides methods of polishing a noble metal-containing substrate with one of two chemical-mechanical polishing compositions. The first chemical-mechanical polishing composition comprises (a) an abrasive comprising α-alumina, (b) about 0.05 to about 50 mmol/kg of ions of calcium, strontium, barium, or mixtures thereof, and (c) a liquid carrier comprising water. The second chemical-mechanical polishing composition comprises (a) an abrasive selected from the group consisting of α-alumina, γ-alumina, δ-alumina, θ-alumina, diamond, boron carbide, silicon carbide, tungsten carbide, titanium nitride, and mixtures thereof, (b) about 0.05 to about 3.5 mmol/kg of ions of calcium, strontium, barium, magnesium, zinc, or mixtures thereof, and (c) a liquid carrier comprising water.
US08101092B2 Method for controlling ADI-AEI CD difference ratio of openings having different sizes
A method for controlling ADI-AEI CD difference ratios of openings having different sizes is provided. First, a first etching step using a patterned photoresist layer as a mask is performed to form a patterned Si-containing material layer and a polymer layer on sidewalls thereof. Next, a second etching step is performed with the patterned photoresist layer, the patterned Si-containing material layer and the polymer layer as masks to at least remove an exposed portion of a etching resistive layer to form a patterned etching resistive layer. A portion of a target material layer is removed by using the patterned etching resistive layer as an etching mask to form a first and a second openings in the target material layer. The method is characterized by controlling etching parameters of the first and second etching steps to obtain predetermined ADI-AEI CD difference ratios.
US08101091B2 Introducer assembly and method for forming an introducer assembly
An introducer assembly includes a sheath having a sheath proximal end and distal end, and a passage therethrough. The introducer assembly further includes a handle assembly that is mechanically and/or bonded coupled with a tubular sheath.
US08101087B2 Element removal process
A process and apparatus for removing elements is described herein.
US08101083B2 Pre-treatment reverse osmosis water recovery method for brine retentate metals removal
A pre-treatment method for cleaning and maintaining reverse osmosis membrane filters by injecting sulfurous acid into waters with suspended solids in a liquid fraction to be filtered to form sulfurous acid (H2SO3) to acid leach heavy metals into the liquid fraction, reduce alkalinity and mineral scaling, add sufficient SO2 as a biocide to attack bacteria and other micro organisms to prevent membrane fouling, reduce iron to prevent iron deposit build-up, scavenge and remove dissolved oxygen prior to filtration to prevent membrane oxidation, and then sequentially filtering the acidified water through membrane filters to create a metal free permeate and a brine retentate, which can be pH adjusted to remove the heavy metals as metal hydroxide precipitates.
US08101082B2 Waste-activated sludge treatment methods and apparatus
A method for treating waste-activated sludge comprises adding (1) a pozzolanic material to waste-activated sludge to form a mixture. The mixture is homogenized and aerated (2). The pozzolanic material reacts with the waste-activated sludge. The mixture is allowed to settle (3). A portion of the mixture is recirculated (4) from a downstream location to an upstream location. The recycled mixture includes pozzolanic material. Some embodiments provide advantages over existing wastewater treatment methods which may include: reduction or elimination of unpleasant odours, reduction of overall costs, conversion of waste into useful products, and/or reduction or elimination of discharged bacteria or other undesirable materials.
US08101081B2 Method of denitrifying wastewater
Disclosed is a method of denitrifying a solution including introducing into the solution an amount of a carbon source within a duration and at a frequency so that indigenous heterotrophic bacteria deplete dissolved oxygen in the solution and obtain oxygen from nitrate in the solution. Related apparatuses and compounds also are disclosed.
US08101077B2 Device for separating platelets from fluid suspensions
A device for separating platelets from a fluid suspension comprises a mixing chamber operable to receive and mix fluid suspensions and an aggregating agent to form platelet aggregates and residual fluid components. A filter can be configured to be in fluid communication with the mixing chamber and can be further configured to collect platelet aggregates and allow residual fluid components to pass therethrough. The mixing chamber and the filter are operable by a user without input from an external energy source.
US08101071B2 Oil removal reclamation clarifier system and process for use
One aspect of the present disclosure includes an oil removal reclamation clarifier system in communication with a body of oil laden wastewater fluid and a conduit for transporting the fluid to the reclamation clarifier system. The reclamation clarifier system includes an oil removal mixing containment device having an influent port, an agent inlet, a sludge collection section in a lower portion of the device for collecting the dispersed liquid, a sludge outlet, and, at least one decant valves located on or near an upper portion of a sidewall of the oil removal clarifier device for permitting unsettled material to exit from the clarifier.
US08101069B2 External filtering and absorbing device for use in a local containment area
An External Filtering and Absorbing Device for Use in a Local Containment Area contains filter material with a mesh size not less than 50 microns for removing contaminants from ballast or bilge water from a ship or effluent from a storm drain. Examples of contaminants removed are aquatic nonindigenous species such as Fish, Zebra and Quagga Mussels, Asiatic Clam, Aquatic Weeds, Green Crabs, or other suspended particle contaminants. Filtering is accomplished above the ambient water allowing easy visual verification and visual gratification of the efficacy of the filter unlike closed on-board systems. Water and oil permeate the filter and flow into a local containment area where oil is absorbed by absorbent pads held in pockets. The filter is easily removed and can be sent to authorities to demonstrate compliance with environmental standards. Water sampling containers or instruments used with the assembly allow for further compliance monitoring.
US08101066B2 Fluidized coking process
An improved fluidized coking process wherein an effective amount of a basic material, preferably an alkali or alkaline-earth metal-containing compound, is added to the coking zone to mitigate agglomeration of the coke during the coking of a heavy hydrocarbonaceous feedstock to produce lower boiling products.
US08101062B2 System and methods for determination of analyte concentration using time resolved amperometry
A method for determining a concentration of an analyte is disclosed. The method includes applying a potential excitation to a fluid sample containing an analyte and determining if a current decay curve associated with the fluid sample has entered an analyte depletion stage. The method also includes measuring a plurality of current values associated with the fluid sample during the analyte depletion stage and calculating an analyte concentration based on at least one of the plurality of current values.
US08101061B2 Material and device properties modification by electrochemical charge injection in the absence of contacting electrolyte for either local spatial or final states
In some embodiments, the present invention is directed to processes for the combination of injecting charge in a material electrochemically via non-faradaic (double-layer) charging, and retaining this charge and associated desirable properties changes when the electrolyte is removed. The present invention is also directed to compositions and applications using material property changes that are induced electrochemically by double-layer charging and retained during subsequent electrolyte removal. In some embodiments, the present invention provides reversible processes for electrochemically injecting charge into material that is not in direct contact with an electrolyte. Additionally, in some embodiments, the present invention is directed to devices and other material applications that use properties changes resulting from reversible electrochemical charge injection in the absence of an electrolyte.
US08101059B2 Methods of making titania nanostructures
Electrochemical methods for making titanium oxide (TiO2) nanostructures are described. The morphology of the nanostructures can be manipulated by controlling reaction parameters, for example, solution composition, applied voltage, and time. The methods can be used at ambient conditions, for example, room temperature and atmospheric pressure and use moderate electric potentials. The methods are scalable with a high degree of controllability and reproducibility.
US08101056B2 Electrochemical cell
A hollow electrochemical cell is provided. In one exemplary embodiment, a hollow electrochemical cell includes two sets of electrodes and an opening for admitting an analyte to the cell. At least one of the two sets of electrodes can be in fluid communication with the opening. Further, a first set of electrodes can include a working electrode spaced from a counter or counter/reference electrode by less than 500 μm one embodiment the working and counter or counter/reference electrodes are not co-planer. In another embodiment the working and counter or counter/reference electrodes are of substantially corresponding area. In yet another embodiment the working and counter or counter/reference electrodes are spaced from 100 to 200 μm apart. The first set of electrodes and the second set of electrodes can be spaced apart by greater than about 500 μm. Other embodiments of a hollow electrochemical cell are also provided, as are several embodiments of a glucose sensor.
US08101054B2 Magnetic particle trapper for a disk sputtering system
A magnetic particle trapper for use in a sputtering system includes a roller cover plate having a plurality of openings arranged and dimensioned to accommodate a plurality of rollers associated with a mechanical transport mechanism of the sputtering system, and a plurality of magnets to trap magnetic particles, the plurality of magnets being attached to the roller cover plate in locations proximate to the plurality of openings.
US08101047B2 Method of correcting gypsum crystal water effect on infrared moisture measurement
Ash composition measurements of calcium carbonate and gypsum in paper is accomplished with a dual X-ray sensor system with one X-ray source that is powered at about 5.9 KV and a second X-ray source that is powered at about 4.2 KV. Corresponding detectors measure radiation from the respective X-ray sources that is emitted from the paper. Data derived from the measurements yields the gypsum and crystal water content in the paper. The dual X-ray sensor system can be employed in conjunction with infrared total moisture measurements of paper products being manufactured on a papermaking making machine, which contain gypsum and calcium carbonate, in order to correct for the gypsum crystal water effect.
US08101046B2 Methods for producing coating base papers and coated papers
The present invention provides methods for producing a base paper for coated printing paper and a coated paper by neutral papermaking using a roll and blade gap former type paper machine including a drainage mechanism based on a drainage blade immediately downstream of initial drainage via a forming roll, comprising adding a cationic polyacrylamide-based material having a weight-average molecular weight of 10,000,000 or more determined by intrinsic viscosity measurement as a retention aid to a stock to convert it into paper. According to the present invention, the retention, formation and internal bond strength of the stock can be improved. In the present invention, an anionic microparticle and/or a coagulant can also be used.
US08101043B2 Colored primer compositions and methods
A method for bonding a substantially transparent substrate within an opening of a structure, including steps of applying to a substantially transparent substrate a primer composition that includes a colorant; applying an adhesive to the structure defining the opening; and installing the substantially transparent substrate within the opening, wherein the resulting installed substrate is substantially free of any ceramic enamel. Also disclosed are assemblies that include a primer composition that includes a colorant and is substantially free of any ceramic enamel.
US08101041B2 Method to improve adhesion of a formed gasket to plastic closures
A method of attaching a gasket to a plastic surface includes providing a plastic material having a surface; applying sufficient heat to the surface to melt the surface while other portions of the plastic material remain solid; providing a liquid gasket material on the heated surface while the heated surface is melted; and allowing the liquid gasket material and the surface to cool so the gasket is welded to the plastic material.
US08101037B1 Phase-changing sacrificial materials for manufacture of high-performance polymeric capillary microchips
A microchip with capillaries and method for making same is described. A sacrificial material fills microchannels formed in a polymeric substrate, the filled microchannels are covered by a top cover to form filed capillaries, and the sacrificial material is removed to form the microcapillaries. The sacrificial material fills the microchannels as a liquid whereupon it becomes solid in the microchannels, and is liquefied after the top cover is applied and affixed to remove the sacrificial material. The top cover may be solvent sealed on the substrate and of the same or different material as the substrate. The top cover may also be an in situ applied semipermeable membrane.
US08101036B2 Corrosion inhibitors in adhesive bonding of vehicle body structures
In an illustrative embodiment, two panels of different materials may be bonded with a structural adhesive composition comprising microcapsules containing corrosion inhibiting materials for protecting the panels from corrosion. For example, a steel vehicle door outer panel may be bonded to an aluminum alloy or magnesium alloy inner panel using an epoxy adhesive. Dispersed within the uncured adhesive are an abundance of microcapsules filled with a fluid or mobile material for reacting with the iron and/or aluminum or magnesium to inhibit corrosion arising from the facing surfaces of the mixed metal panels. The protective material is released from the microcapsules for diffusion through the cured or uncured interfacial adhesive to react with one or both panel surfaces and form a protective coating on the surfaces.
US08101031B2 Hollow power transmission shaft and method of manufacturing the same
A hollow shaft material is provided with, on an outer peripheral surface side thereof, for example, a movable induction heating coil wrapped therearound. While a high-frequency current with a predetermined frequency is caused to flow through the induction heating coil, the induction heating coil is axially moved to perform induction hardening of the hollow shaft material from the outer peripheral surface side. At this moment, the frequency of the high-frequency current caused to flow through the induction heating coil is set relatively low as to the small-diameter portions, which have a relatively small thickness, and the frequency of the high-frequency current caused to flow through the induction heating coil is set relatively high as to the large-diameter portion, which has a relatively small thickness.
US08101030B2 Manufacturing method for composite alloy bonding wire
A manufacturing method for a composite alloy bonding wire is provided. A primary material of Au and Ag is melted in a vacuum melting furnace, and then a secondary metal material of Pd is added into the vacuum melting furnace and is co-melted with the primary material to obtain a Au—Ag—Pd alloy solution. The obtained Au—Ag—Pd alloy solution is drawn to obtain a Au—Ag—Pd alloy wire. The Au—Ag—Pd alloy wire is then drawn to obtain a Au—Ag—Pd alloy bonding wire with a predetermined diameter.
US08101024B2 Removal of minerals from cellulosic biomass
Disclosed is a method for removing minerals from a cellulosic biomass. For example, the biomass may be prewashed with an acid solution and rinsed with water to remove minerals prior to acid saccharification. The removal of minerals may reduce overall acid requirements, and decrease pretreatment costs.
US08101022B2 Crystal-growing furnace system with emergent pressure-release arrangement
A crystal-growing furnace system with an emergent pressure-release arrangement includes an isolated chamber and a furnace upper body. The top board is provided with an opening and three first guides, and the furnace upper body with a lower opening and three second guides, wherein the lower opening of the furnace upper body covers, correspondingly, on the opening of the top board. In case a crystal-growing furnace, combined oppositely by the furnace upper body and the furnace lower body, has an over-high internal pressure, the pressure will overcome the weight of, and lift up the furnace upper body. At this moment, the furnace upper body will slightly move upward and away from enclosing the furnace lower body, so that the over-high internal pressure in the furnace will be released immediately to prevent the furnace from being exploded and from resulting in public accidents.
US08101020B2 Crystal growth apparatus and manufacturing method of group III nitride crystal
A crystal growth apparatus comprises a reaction vessel holding a melt mixture containing an alkali metal and a group III metal, a gas supplying apparatus supplying a nitrogen source gas to a vessel space exposed to the melt mixture inside the reaction vessel, a heating unit heating the melt mixture to a crystal growth temperature, and a support unit supporting a seed crystal of a group III nitride crystal inside the melt mixture.
US08101019B2 Method for producing a monocrystalline or polycrystalline semiconductor material
In the method of making a monocrystalline or polycrystalline semiconductor material semiconductor raw material is introduced into a melting crucible and directionally solidified using a vertical gradient freeze method. The molten material trickles downward, so that the raw material that has not yet melted gradually slumps in the melting crucible. The semiconductor raw material is replenished from above onto a zone of semiconductor raw material which has not yet melted or is not completely melted to at least partly compensate for shrinkage of the raw material and to raise the filling level. To reduce the melting time and influence the thermal conditions in the system as little as possible, the semiconductor raw material to be replenished is heated to a temperature below its melting temperature and introduced into the crucible in the heated state.
US08101018B2 Method for fabricating a semiconductor device and apparatus for inspecting a semiconductor
In a method for fabricating a semiconductor device and an apparatus for inspecting a semiconductor, laser processing is performed at different laser powers at different positions on a monitor substrate from a plurality of substrates having undergone an SPC step, to form polycrystalline silicon film over the entire area of the substrate. Thereafter, in an optimum power inspection/extraction step, the polycrystalline silicon film formed with varying film quality on the monitor substrate is inspected on inspection equipment to determine the optimum laser power. Then, in a laser processing step, the surface of the subsequent substrates having undergone the SPC step is irradiated with laser at the optimum laser power. Thus, high-quality polycrystalline silicon film is formed over the entire area of the substrate.
US08101010B2 Gas separation module
A porous structure sealed at both ends for use in a gas separation module; and a method for separating components of a gas stream.
US08101009B2 Separation membrane by controlled annealing of polyimide polymers
This abstract discusses membranes needed to separate fluids for the production of oxygen-enriched air, nitrogen-enriched-air, for the separation of carbon dioxide from hydrocarbons, and the separation of hydrogen from various petrochemical and oil refining streams. Membranes are needed that provide a resistance to interaction with process components or contaminants, provide the mechanical strength required to withstand high membrane differential pressures and high process temperatures, and exhibit sufficient maximum strain such that membranes are not brittle and can easily be formed into desirable membrane forms. Membranes of polyimide polymers, particularly polyimide polymers sold under the trade name P-84, are annealed in a controlled annealing step to improve the mechanical properties of the polymers used to make separation membranes. The resulting annealed polyimide polymer is used to produce various forms of high strength, chemically resistant membranes, including hollow-fiber membranes that are suitable for high pressure, high temperature applications.
US08101005B2 Process of making metal nanoparticles
A process is described for making metal nanoparticles comprising (a) forming a liquid melt of a first metal having the composition of the desired nanoparticles and a second metal; (b) quenching the melt to form a solid; and (c) removing the second metal from the solid and forming the nanoparticles comprising the first metal.
US08101000B2 Wireless network infrastructure
An access point of a network maintains information about data received at the access point from a server accessible via the network and provides to the server the information maintained at the access point. The access point then receives from the server a payment for an account associated with an operator of the access point.
US08100992B2 Biomass gasification apparatus
A biomass thermochemical gasification apparatus is provided that can manufacture high-quality fuel gas out of solid biomass in an industrial manner. This fuel gas can be used as fuel for a gas engine and a gas turbine for example and also can be used as synthesis gas for methanol synthesis.A high-temperature combustion gas generation apparatus (101) for biomass operates entirely by biomass and the heat source thereof does not depend on fossil fuel. A coarsely-ground powder biomass (205) subjected to gasification and gasification agent (303) are introduced to a primary gasification reaction room (202) and generate gasification reaction by, as reaction heat, radiation heat from a wall face of the primary gasification reaction room (202) heated by combustion gas (109a) generated in the high-temperature combustion gas generation apparatus (101) and are dissolved. Consequently, the biomass (205) is converted to clean and high-quality generated gas.
US08100981B2 Tibial prosthesis
The present invention relates to a tibial prosthesis useful in knee replacement surgeries. The prosthesis includes one or more cement introduction ports which may be used to deliver and control delivery of bone cement to a prosthesis-bone interface after the prosthesis has been positioned on a resurfaced area of a tibia bone. The prosthesis is suitable for implantation using arthroscopic as well as open surgical procedures. The prosthesis may be used as a unicondylar implant in either compartment of the knee or in both compartments of the knee.
US08100971B2 Coatings for spinal implants
The present application describes a spinal implant device comprising a load-bearing component having at least one soft tissue-facing surface and a coating affixed to the soft tissue-facing surface. The coating is operable to define an interface with the soft tissue that exhibits one or more of the following features: reduced friction, reduced tissue irritation, reduced adhesion, reduced inflammation, reduced incidence of infection and reduced pain, relative to the soft tissue-facing surface in the absence of the coating. Other embodiments include methods of use and manufacture of the apparatus. The application also describes a method involving affixing a load-bearing prosthetic spinal implant device to first and second vertebrae of a motion segment and, after the device is affixed, applying to a soft tissue-facing surface of the device a flowable, curable coating material operable to cure in situ to form a coating.
US08100970B2 Biological surgical patch and method of making
A biological surgical patch made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate, minimizing the antigens from the substrate, tanning the substrate, and incorporating an active layer in the substrate.
US08100966B2 Auditory ossicle prosthesis with variable coupling surfaces
An auditory ossicle prosthesis (10) which comprises, at one end, a plate-shaped first securing element (11) for bearing on the tympanic membrane or on the footplate of the stirrup, and, at its other end, a second securing element (12) for mechanical connection to the ossicular chain or to the inner ear, and also a connection element (13) that connects the two securing elements so as to conduct sound, wherein the first securing element has a radially inner coupling area (14) for coupling the first securing element to the connection element, and also a plurality of web elements (15, 15′, 15″) for radial connection of the coupling area to radially outer portions (16, 16′) of the first securing element, is characterized in that the coupling area and/or the web elements and/or the radially outer portions are of such a geometric configuration that they together form pieces of a jigsaw from which the first securing element can be assembled in its entirety, wherein the individual jigsaw pieces can be joined to one another or removed from one another, and wherein the first securing element is inherently mechanically stable in the state with the jigsaw pieces joined together. This means that the number of different prostheses to be kept ready during an operation can be reduced to a single standard prosthesis, without losing the possibility of optimal adaptation of the prosthesis to the specific case of use.
US08100965B2 Floating optic accommodating intraocular lens
An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and a weakened portion connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.
US08100963B2 Biodegradable device
A device that is at least partially formed of a biodegradable polymer. The device can be at least partially formed by MEMS technology. The device can include one or more micro-structures that are also formed by MEMS technology. The device can include one or more agents that can be controllably and/or uncontrollably released from the device.
US08100958B2 Device for delivering a self-expanding stent in a vessel of the body
The present invention relates to a device for delivering a self-expanding stent in a vessel of the body. The device comprises a tubular sheath which, in a distal section, keeps the stent radially compressed, and a pusher element, which is guided in the tubular sheath, in order to stabilize the stent when the sheath is pulled back. A handle is also provided, with a passage via which the pusher element is secured on the handle. The device further comprises a tubular rod which is fixedly connected to the handle and inside which the pusher element is provided, and which is provided at least in part with regularly spaced elevations and with depressions lying between the elevations. In addition, a movable element is provided which is arranged movably over the rod, distally from the handle, and whose movement in the proximal direction allows the sheath to be pulled back.
US08100955B2 Orthopedic expansion fastener
Methods and devices are disclosed for treating the vertebral column. An integrated fixation plate and spacer having a retaining structure within the screw holes of the fixation plate to resist backout of screws attaching the fixation plate to the bone is provided. A movable joint may be provided between the fixation plate and spacer. In some embodiments, a screw hole insert is also provided to resist shear forces acting between the screw and fixation plate. In some embodiments, an integrated fixation plate and spacer system is provided, comprising two or more integrated fixation plate and spacer implants, wherein the fixation plates of each implant has a complementary configuration to allow attachment of the implants at adjacent intervertebral spaces. Alternative fixation systems are also contemplated.
US08100953B2 Bone plate with complex, adjacent holes joined by a relief-space
A bone plate is described which is adapted for use in situ to fix a spatial relationship of at least two bone parts. The bone plate has at least one pair of the bone screw apertures that are adjoined by a relief-space contiguous with the open space of the screw apertures themselves. An adjoined aperture pair forms a complex aperture and has a center-to-center distance d of the apertures along an axis running through the centers of the apertures. The center-to-center distance d is equal to or greater than the sum of the radii (r1+r2) of the heads of the individual bone screw used with the aperture pair.
US08100950B2 Oblique lumbar interbody fusion
A method fuses an inferior vertebra and a superior vertebra together. The method includes the steps of: extending a screw obliquely, both anteriorly and superiorly, through the inferior vertebra; and further extending the screw across an interbody space and into the superior vertebra both anteriorly and superiorly.
US08100944B2 Inter-cervical facet implant and method for preserving the tissues surrounding the facet joint
Systems and method in accordance with the embodiments of the present invention can include an implant for positioning within a cervical facet joint for distracting the cervical spine, thereby increasing the area of the canals and openings through which the spinal cord and nerves must pass, and decreasing pressure on the spinal cord and/or nerve roots. The implant can be inserted laterally or posteriorly.
US08100932B2 Method and apparatus for treating obesity and controlling weight gain using self-expanding intragastric devices
The invention generally relates to a method and apparatus to treat obesity and controlling weight gain. In an exemplary embodiment, the invention relates to a covered cage device that is implanted within a human's stomach to occupy volume and cause a reduced desire for eating. The covered cage device is made from a wire-mesh, such a Nitinol, and can be adjustable and collapsible. In another embodiment, the covered cage device has edges that provide stimulation to the stomach to induce a feeling of fullness.
US08100931B2 Bariatric device and method
A bariatric device and method of causing at least partial satiety includes a body that is adapted to be positioned at i) an abdominal portion of the esophagus and/or ii) a proximal cardiac portion of the stomach. The body has a wall defining a lumen. The wall is configured to generally conform to the shape and size of i) the abdominal portion of the esophagus and/or ii) the proximal cardiac portion of the stomach. A force is exerted with the wall at i) the abdominal portion of the esophagus and/or (ii) the proximal cardiac portion of the stomach thereby influencing a neurohormonal feedback mechanism of the patient to cause at least partial satiety by augmenting fullness caused by food and simulating fullness in the absence of food. The method further includes adjusting the force exerted with the wall.
US08100929B2 Duckbill seal with fluid drainage feature
Seal assemblies, generally for use in trocar assemblies, are provided for selectively promoting movement of fluid away from a central portion of the seal assemblies. In one exemplary embodiment, an inner surface of a seal body of the seal assembly is configured to selectively promote such movement of fluid away from the central portion of the seal body toward a peripheral portion of the seal body. While various configurations, geometries, and dimensions are discussed, one example of such a configuration includes locating a central portion of the seal body at a more proximal position than a peripheral portion of the seal body.
US08100926B1 Surgical clip
A surgical clip comprises an upper jaw (12) and a lower jaw 14), a section lining, and includes a complex shape for the upper jaw (12) comprising a first generally straight section (120) and a second shallow curved section (122) thereby enabling the clip to be inserted down a narrow magazine tube and to be able to be operable into a wide capture opening to capture larger vessels and then closed into a latched position on application of force the relatively straight section (120) and then to the shallow curved section (122).
US08100920B2 Endoscopic tissue apposition device with multiple suction ports
The present invention relates to an improved endoscopic tissue apposition device having multiple suction ports. The invention permits multiple folds of tissue to be captured in the suction ports with a single positioning of the device and attached together by a tissue securement mechanism such as a suture, staple or other form of tissue bonding. The improvement reduces the number of intubations required during an endoscopic procedure to suture tissue or join areas of tissue together. The suction ports may be arranged in a variety of configurations on the apposition device to best suit the desired resulting tissue orientation. The inventive tissue apposition device may also incorporate tissue abrasion means to activate the healing process on surfaces of tissue areas that are to be joined by operation of the device to promote a more secure attachment by permanent tissue bonding.
US08100907B2 Jawed surgical instrument fitted with an electrode and a cable
A jawed surgical instrument fitted at the distal end of a jaw head which is affixed at the distal end of a longitudinally elongated stem and which supports two mutually oppositely displaceable jaw parts, the jaw head being connectable by means of an actuation bar to one of two drive elements of a manipulating unit that are mutually oppositely displaceable in the stem direction, the other of the drive elements being connected to the stem. The jaw head comprises at least one electrode designed for tissue surgery and is electrically connected by means of the actuation bar to a cable issuing from the bar, the actuation bar and the jaw head being detachably connected to the manipulating unit wherein the actuation bar and the jaw head are detachably connected transversely to the stem direction or in the proximal direction parallel to the stem to the manipulating unit.
US08100902B2 Electrode with rotatably deployable sheath
A sheath system for selectively covering a distal end of an electrocautery blade is provided. The sheath system includes a hub having a body portion defining a lumen therethrough and a sheath having a body portion defining a lumen therethrough. The lumen of the sheath is configured and dimensioned to operatively receive an electrocautery blade therein. The sheath is translatably associated with the hub such that rotation of the hub in a first direction results in axial movement of the sheath in a first direction to expose a distal end of the electrocautery blade and rotation of the hub in a second direction, opposite to the first direction, results in axial movement of the sheath in a second direction to cover the distal end of the electrocautery blade. The hub and the sheath may be concentric with one another.
US08100897B2 Laparoscopic electrosurgical electrical leakage detection
An electrical leakage detection method and system for use with laparoscopic electrosurgical instruments are provided. The present disclosure provides for an electrosurgical unit for providing electrosurgical energy at an active output thereof and for controlling the flow of the energy through the active output; an active electrode coupled to the active output for transmitting electrosurgical energy to a patient in an electrosurgical procedure; a first sensor disposed at a distal end of the active electrode and for outputting a first signal indicative of current measured at the distal end; a second sensor disposed at a proximal end of the active electrode and for outputting a second signal indicative of current measured at the proximal end; and a comparison circuit coupled to the first and second sensors for receiving the first and second signals and determining a difference value, the difference value being indicative of leakage current.
US08100894B2 Heat pipe for cautery surgical instrument
A heat pipe for a cautery surgical instrument such as a surgical forceps including a pair of elongate arms joined at an end so as to provide for resilient compressible movement of the arms between a normally open position and a squeezed closed position. The heat pipe provides for conduction of heat away from an electrode tip, and comprises an evaporator portion having a first diameter and a condenser portion spaced away from the evaporator end, and that transitions from the first diameter to at least one smaller diameter section. A socket is disposed within each arm of the forceps and includes a longitudinal blind hole that is sized so as to releasably receive the smaller diameter section of the condenser portion, and a catch for engaging a portion of the arm.
US08100892B2 Medical suction device
A medical device for fragmenting objects and aspirating remaining debris enables a physician or other medical personnel quickly and easily remove objects, such as kidney stones, from a patient. The medical device can include a dual-lumen elongated member and a handle coupled to the elongated member. A first one of the lumens provides a suction passageway, and a second one of the lumens receives a laser fiber for delivering laser energy to an object, such as a kidney stone, within the patient. The handle can include a positioning mechanism to enable the physician by manual manipulation to move and hold in place the laser fiber longitudinally within the second lumen.
US08100885B2 Cap assembly for use with a prefilled lock solution syringe
A cap assembly is disclosed for use with a lock solution delivery device. The cap assembly includes a housing defining a receptacle and having an inlet end and an outlet end. A plunger is movable axially within the receptacle from a retracted position to an advanced position and is rotatably supported within the receptacle from a first position to a second position. The plunger includes an axial extension configured to non-rotatably engage a syringe connected to the inlet end of the housing. The plunger is positioned to move from the first position to the second position in response to rotatable detachment of a syringe from the inlet end of the housing.
US08100879B2 Connector device for enteral administration set
The present invention relates to a connector device suitable for connecting an enteral administration set to a laminated paper packaging system comprising enterally administrable medical or nutritional food.
US08100877B2 Absorbent article
An absorbent article including a chassis having a front body and a back body with a waist opening and leg openings, and an absorbent body of higher stiffness than that of the chassis. The front body and the back body consist of a composite sheet stretchable in the width direction WD. A line DL and a line CL2′ form an angle in the range of 0 to 50 degrees. DL is a line connecting a bottom-most point PI on the connection between the front body and back body edge portions, and point P2 where the back body meets a crotch portion. CL2′ is a line in the transverse direction of the article which passes through the end point P2.
US08100868B2 Anti-drawback medical valve
A gland member within a medical valve is configured to have a substantially consistent or enlarging internal volume as the valve transitions from a closed mode to an open mode. To that end, the valve has a housing forming an interior containing a flow path, and a stationary post member within the interior. The post member has a lumen that is a part of the flow path. The lumen has an opening to the interior of the housing. The valve further includes a gland member circumscribing the post member to produce a variable volume region formed at least in part between the gland member itself and the post member. In addition, the variable volume region is a part of the flow path, while the gland member occludes the post lumen opening when in the closed mode. The variable volume region has an open volume (i.e., when the valve is in the open mode) that is no less than its closed volume (i.e., when the valve is in the closed mode).
US08100867B2 Needle
A needle (1, 100, 110) for precision filling of dosage containers, such as vials, ampoules etc. is provided. The needle ideally comprises an elongate plastics body (2) having a through channel (5) extending between inlet (3) and outlet (4) openings. A tip portion (7b) at the outlet opening (4) has a chamfer (8) tapering towards the outlet opening (4) and an end surface (9) around the opening so that the tip portion (7b) is frusto-conical. The surface area of the end surface (9) is sufficiently smaller than the area of the cross-section of the needle body (2) so that in use the needle (1) is capable of providing for formation of smaller droplets of liquid at the outlet (4) compared to needles without such body thickness reduction at the time when the liquid flow through the needle is shut off. The end surface (9) may be so narrow as to take the form of a sharp rim.
US08100864B2 Portal device
A method of maintaining an opening formed in a patient is provided. The method includes inserting a first elongated structure and a second elongated structure through the opening in the a patient, the second elongated structure being moveable within the first elongated structure. The first elongated structure is moved relative to the second elongated structure thereby causing an outside dimension of the second structure to increase in size.
US08100856B2 Balloon catheter
The invention discloses a balloon catheter comprising a catheter shaft, at the distal end of which an inflatable balloon is arranged and at the proximal end of which a connecting piece is arranged, comprising a guiding wire which can be passed through a guiding wire lumen of the catheter shaft from the proximal end to the distal end and through the balloon and an inflation or deflation lumen extending from the proximal end of the catheter shaft to the balloon, wherein a portion of the catheter shaft having a selectable length and extending from the proximal end is provided with a metal reinforcing pipe.
US08100849B2 Method and apparatus to remove substances from vessels of the heart and other parts of the body to minimize or avoid renal or other harm or dysfunction
To accomplish isolation and removal of a substance from a vasculature, a catheter is employed to occlude a vessel of the vasculature. The substance is thus isolated in the vasculature and can be removed. In this way, the substance is removed before entering other parts of the circulatory system. This method is applicable to removal of contrast from the coronary sinus shortly after injection of the coronary arteries with the contrast. The method substantially minimizes or avoids renal dysfunction caused by angiographic procedures in which contrast must be injected. Such angiographic procedures are often performed during intervention procedures. This method substantially prevents circulation of the contrast to the kidneys where it could otherwise cause renal dysfunction or failure. The apparatus for implementation of the method is also disclosed.
US08100848B2 Reduced-pressure, compression systems and apparatuses for use on breast tissue
A system uses reduced pressure to provide a therapeutic force to a person's breast area. The system includes a dressing assembly shaped and configured to be placed on the breast area, a releaseable circumferential connector for holding the dressing assembly against at least a portion of the breast area, and a sealing subsystem for providing a fluid seal over the dressing assembly against a person's epidermis. The system may further include a reduced-pressure subsystem for providing reduced pressure to the dressing assembly. When reduced pressure is supplied, the system generates a force against at least a portion of the breast area of the person. The dressing assembly may be formed as a brassiere having a first cup and a second cup formed from a bolster material.
US08100846B1 Spinal traction and restoration using pointable constrained inflator
Spinal traction and restoration using application of forces in user-selectable distinct unitary directions by a rotatable pointable constrained inflator proximate a device base. The constrained inflator provides selectable, variable and pointable force to effect any of the following therapies: [1] Axial Traction; [2] Force to Upper Cervical Spine; [3] Force to Mid-Cervical Spine; [4] Force to Lower Cervical Spine; and [5] Traction Force Applied to Upper Thoracic Spine.
US08100845B2 Ankle support with calcaneous control strap
A foot support having straps which receive the calcaneous and wrap around the midfoot in a tensioned state for stabilizing the rearfoot and the midfoot to avoid excessive inversion and eversion of the foot.
US08100840B2 Remote cervical dilation monitoring system and method
A method of monitoring the cervical dilation of a pregnant female, comprising the steps of receiving cervical dilation data generated by a cervical dilation monitor having a sensor including a coil measuring an inductance with the coil attached to a housing such that expansion of the housing changes the inductance of the coil. Then, the cervical dilation is correlated to the immediacy of delivery to create immediacy data and/or one or more instructions indicative of the immediacy of delivery. The immediacy data and/or one or more instructions is transmitted so as to inform the pregnant female of the immediacy of delivery.
US08100837B1 Superelastic guidewire with locally altered properties
A guidewire formed at least in part of a superelastic member with a section having one or more altered properties including physical and mechanical properties. Preferably, the section of altered property has reduced superelasticity with respect to the remainder of the superelastic member. The invention also comprises method of manufacturing such guidewires wherein a section of the superelastic member is isolated and treated to change one or more of the properties. The treatment may be alloying with a diffusable element or isolating one or more sections to work and heat treat to decrease superelasticity relative to the rest of the member. The section having one or more altered properties is preferably a distal portion of the member, for example about the most distal 3 cm.
US08100836B2 Augmented RIC model of respiratory systems
The present invention generally relates to an apparatus and method analyzing the respiratory characteristics of a human respiratory system from impulse oscillometry data, through the use of a linear network of electrical components. The present invention offers an improved alternative to the RIC respiratory circuit model, with an addition of a peripheral resistance to account for the resistance presented by the respiratory system's small airways and of a capacitor to account for extrathoracic compliance. After air pressure and air flow measurements are obtained from the subject by performing Impulse Oscillometry System testing, a graphical representation of a mechanical impedance characteristic may be derived. This allows for the estimation and adjustment of parameter values of the linear network whose components correlate to the resistances, compliances and inertances inherent in the respiratory system. Additionally, the linear network of electrical components may be configured as a virtual network represented in graphical form wherein the parameter values are estimated and adjusted according to program instructions operating on a computer system. The linear network of electrical components serves to provide parametric means for detection, diagnosis and treatment of various pathologies in the human respiratory system.
US08100831B2 Direct strain estimator for measuring elastic properties of tissue
Ultrasound data of a biological tissue is acquired in a relaxed state and a tensed state. A strain is estimated directly from the relaxed state ultrasound data and the tensed state ultrasound data by way of an imaginary part of a complex correlation function. In estimating the strain, the tensed state ultrasound data is re-stretched, and the imaginary part of the complex correlation function is calculated from this re-stretched ultrasound data and the relaxed state ultrasound data. A slope factor is also calculated, and the strain is estimated from this slope factor and the imaginary part of the complex correlation function.
US08100830B2 Non-therapeutic methods of evaluating skin neurosensitivity, kit and use of a kit for implementing the method
The invention relates to new non-therapeutic methods allowing the level of skin neurosensitivity and/or the state of neurosensorial skin reactivity of an individual to be evaluated by applying a peripheral nervous system stimulant to one skin area, the method being implemented under conditions of safety and comfort acceptable for the user, irrespective of his or her skin type.
US08100825B2 Endoscope and supportive member for bending operation of the same
An endoscope includes an insertion portion having a bendable portion; an operation portion from which the insertion portion extends; a first bending operation knob arranged on a surface of the operation portion and including depressions and first protrusions, to bend the bendable portion in a first direction when rotated; and a second bending operation knob arranged over the first bending operation knob and including depressions and second protrusions, to bend the bendable portion in a second direction when rotated. A length of the second protrusion from a center of rotation to a tip portion is longer than a length of the first protrusion from the center of rotation to tip portions of the first protrusions, and the second protrusion has a depression near a projection of a circular orbit of rotation of each tip portion of the first protrusions onto a surface facing the first bending operation knob.
US08100824B2 Tool with articulation lock
The invention provides surgical or diagnostic tools and associated methods that offer user control for operating remotely within regions of the body. These tools include a proximally-located actuator for the operation of a distal end effector, as well as proximally-located actuators for articulational and rotational movements of the end effector. Control mechanisms and methods refine operator control of end effector actuation and of these articulational and rotational movements. An articulation lock allows the fixing and releasing of both neutral and articulated configurations of the tool and of consequent placement of the end effector. The tool may also include other features. A multi-state ratchet for end effector actuation provides enablement-disablement options with tactile feedback. A force limiter mechanism protects the end effector and manipulated objects from the harm of potentially excessive force applied by the operator. A rotation lock provides for enablement and disablement of rotatability of the end effector.
US08100821B2 Low friction delivery tool for a cardiac support device
A delivery device for efficiently delivering a cardiac support device of the type having a jacket. The device includes a body, a deployment mechanism and an actuating mechanism. The deployment mechanism is for releasable connection to a cardiac support device and movable within the jacket between retracted and extended states to drive the jacket between collapsed and open configurations. At least portions of the deployment mechanism within the jacket have a lubricious surface to substantially reduce friction between the jacket and a heart onto which the jacket is being positioned. The actuating mechanism moves the deployment mechanism between the retracted and extended states.
US08100818B2 Beta radiotherapy emitting surgical device and methods of use thereof
A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).
US08100815B2 Exercise device
An exercise device comprising a frame; and a plurality of platforms for accommodating an exerciser's feet, each platform of the plurality of platforms including at least one moving member for facilitating both a divergent movement and a convergent movement. The device includes a tensioning structure for providing adjustable resistance.
US08100813B2 Trampoline and the like with enclosure
A fence surrounds a trampoline and extends above the rebounding surface, reducing the risk of injury. Shock absorption is aided by a support system of independent poles, linked at their tops by a flexible strap or line which is attached directly to a protective cap at the top of each pole. Also disclosed are a method and apparatus for attaching a pad to a trampoline frame either with or without an enclosure.
US08100811B2 Automatic disengaging/engaging method of a clutch dependent power take-off
An automatic disengaging method for a master clutch dependent power take-off (PTO) arranged in a vehicle for preventing undesired movement or actions of the implements associated with the PTO and undesired wear of a clutch collar (release bearing). The PTO is driven by an engine via a master clutch between a crankshaft of the engine and an input shaft in a gearbox. The gear box further comprises an output shaft which is powered by the input shaft, optionally via an intermediate shaft. A power take-off is connected to the input shaft or, optionally, to the intermediate shaft. The system further includes a control unit connected to the master clutch and the gear box. When the control unit registers that the master clutch is disengaged, a gear is engaged in the gearbox and certain conditions are fulfilled (e.g. a parking brake has been actuated for a certain time), the control unit performs the operations of putting the gearbox in a neutral position, disable the power take-off, if the power take-off is enabled, and engage the master clutch.
US08100809B2 Automatic transmission
A first element of a duplex planetary gear set is selectively coupled to an input shaft via a third clutch, or is selectively fixed via a first brake. A second element is selectively coupled, via a second clutch, to an intermediate shaft that is directly coupled to a speed-increasing element of a simplex planetary gear set which increases the rotational speed of the input shaft, or is selectively fixed via a second brake. A third element is directly coupled to an output shaft. A fourth element is selectively coupled to the input shaft via a first clutch. Therefore, by increasing the speed of the rotation of the input shaft by the simplex planetary gear set and transferring it to the duplex planetary gear set, it is possible to reduce the torques on individual components of an automatic transmission and therefore to reduce the sizes of the individual components and the capacities of the individual friction engagement elements.
US08100807B2 Reduction gear transmission and solar tracking photovoltaic power generation unit utilizing the same
A first reduction gear unit has a first input shaft that rotates in accordance with the rotation of an output shaft of a motor, a first external gear that revolves orbitally around an axis line of the first input shaft, and a first internal gear that has a number of teeth differing from the number of teeth of the first external gear. A second reduction gear unit comprises a crankshaft that rotates in accordance with the rotation of a first output shaft, a second external gear having a through hole formed at a center itself, a cylindrical member passing through the through hole of the second external gear, a second internal gear that has a number of teeth differing from the number of teeth of the second external gear, and a second output shaft that rotates around an axis line of the second internal gear. The first reduction gear unit is disposed between an outer circumferential surface of the second reduction gear unit and an inner surface of the cylindrical member.
US08100805B2 Electronically controlled locking differential having logic-control wire harness
An electronically controlled locking differential includes an electromagnetic coil and a wire harness adapted to logically control operation of the differential and having a circuit. The circuit has a latching switch that is electrically connected to a first source of power and adapted to provide latching power of the differential. A double-pole, double-throw control relay is electrically connected to the latching switch and includes a first switch, a second switch, and a coil. The second switch is adapted to “jump” the latching switch. The circuit is disabled when power to the harness is turned off and in “standby” mode when power to the harness is turned on. Upon the latching switch being activated, current flows from a starting point of the circuit through the circuit to activate the relay, the first switch closes to energize the differential, the second switch closes such that the current “jumps” the latching switch, and the differential is actuated.
US08100804B2 Hydraulic control system and method for automatic transmission for a vehicle
A hydraulic control system for an automatic transmission, which includes a brake, used to establish a first gear step and a reverse gear step. The hydraulic control system includes a first solenoid valve, a second solenoid valve and a control valve, which is switched by a hydraulic signal from the second solenoid valve, and that are operated simultaneously to engage the first-gear step and reverse gear step engagement element; and an neutral gear position engagement control unit that activates both solenoid valves when a shift lever is shifted to neutral to engage the brake. Thus, the generation of a shock may be prevented when the shift lever is shifted from the N position to an R position.
US08100802B2 Torque converter control method and apparatus
A method for controlling a torque converter having an internal lockup clutch includes detecting vehicle operating conditions and executing one of a stored plurality of torque converter clutch modes each corresponding to a different set of vehicle operating conditions. A fully-released mode corresponds to vehicle pre-launch, a partially-engaged mode corresponds to post-launch of the vehicle in first gear, downshift, coasting, throttle tip-in, or throttle tip-out; a first fully-engaged mode corresponds to steady-state operation in second gear or a higher; and a second fully-engaged mode corresponds to an upshift. Slippage across the converter is controlled only during the first fully-engaged mode. A vehicle is also provided having an engine, transmission, torque converter with lockup clutch, and controller having a control algorithm. The algorithm executes a different lockup clutch mode based on the detected vehicle operating conditions, and the slippage across the converter is controlled during only one lockup clutch mode.
US08100796B2 Elevator belt assembly with prestretched cords
An elevator load bearing assembly (40) includes a plurality of synthetic or polymer cords (42) within a urethane jacket (44). The cords are prestretched and the jacket prevents the stretched cords from relaxing. The inventive arrangement provides a load bearing assembly (40) that has little or no elastic or construction stretch.
US08100785B2 Baseball area protection system and method
This invention relates to an integrally weighted baseball cover and system, method and apparatus for quickly delivering the cover and placing it onto an area of a baseball field, such as one or more of the infield areas, such as home base area, first base area, second base area, third base area, pitcher's mound area and/or bullpen areas.
US08100783B2 Tennis serve training device
A tennis skill training device having grip emulating a tennis racquet grip sized to be held by a user. The device includes a grip, a single flexible umbilical having a first and second ends, the first end being attached to and emanating from the distal end of the grip, and a weight attached to the second end of the umbilical.
US08100781B2 Metal wood club with improved moment of inertia
A more efficient triangular shape for metal wood clubs or driver clubs is disclosed. This triangular shape allows the clubs to have higher rotational moments of inertia in both the vertical and horizontal directions, and a lower center of gravity.
US08100778B2 Golf training device
The present invention relates to a golf training device and method of use thereof. Specifically, the training device seeks to correct faults in a golfer's swing. The device enables correct alignment and correct swing path to be practised simultaneously while practising both shots or drills requiring a “square” alignment or shots or drills requiring an “open” or “closed” alignment. Furthermore, the device, and method of use thereof, can be used by all sizes of golfer, using all types and sizes of clubs, practising all types of shot.
US08100774B2 Joint having a slip bush
A universal joint includes a tube having a hollow shape; a slip bush inserted into the tube; and a shaft assembled with the tube through the slip bush, wherein the slip bush includes power transmission parts, which are arranged along an circumferential surface of the slip bush in an axial direction and have pins positioned at centers of the power transmission parts and supports supporting both ends of each pin, and elastic parts, which are arranged along the circumferential surface of the slip bush while being spaced from the power transmission parts and have a section with a C-shape, which is formed in such a manner that a side portion is cut out in the axial direction. Therefore, strength and rigidity are improved, even when twist is generated in the universal joint, so that clearance and noise due to abrasion, pressing, etc. can be minimized.
US08100771B2 Game device, server device, game process control method, and information storage medium
In a car racing game, one player is given a crown in racecourse units which indicates that the player is the fastest player (champion) of the racecourse. A player can play a crown competition with the player possessing the crown aiming to acquire the crown. For example, when a player Px challenges the crown of the racecourse 1, the player Px operates a player's car PC and plays a match against a player Pa who is a crown-possessing player of the racecourse 1. Specifically, the player Px plays a match against a ghost car GC controlled based on ghost data Ga1 of the player Pa for the racecourse 1. When the player Px has won the match, the crown of the racecourse 1 possessed by the player Pa is transferred to (acquired by) the player Px.
US08100769B2 System and method for using accelerometer outputs to control an object rotating on a display
An example system and method controls a rotatable object on a display using a handheld control device comprising an accelerometer. The example system and method involve determining an orientation of the handheld control device using an interpolation of an output for a first axis of the accelerometer and an output for a second axis of the accelerometer. The rotation of the rotatable object is controlled based on the determined orientation.
US08100768B2 Storage medium storing game program and game apparatus
A game apparatus includes a plurality of controllers. Each of the controllers is provided with an acceleration sensor, for example, for detecting a motion thereof. A magnitude of a motion value detected by each of the controllers is determined, and a motion with a maximum value is determined to be effective, and a game processing is executed.
US08100764B2 Software security for gaming devices
A secure smart card or other secure modular memory device is plugged into (or otherwise connected to) a port of a game controller board internal to a gaming machine, where it is not accessible to a player. The smart card is programmed to detect an encrypted “challenge” message from the host CPU and output an encrypted “response.” If the host CPU determines that the response has the expected properties, then the host CPU verifies that the game program (an application program) is also is authentic, and the game can be played. The challenge/request exchange may be performed periodically to ensure the smart card is still installed. If the response is improper, then the host CPU will issue a halt command to halt play of the game.
US08100761B2 Gaming machine with a dynamic bonus modifier
There is disclosed a game feature forming part of a gaming machine apparatus (10). The game feature (42) is configured to award a bonus outcome that is determined on the basis of a dynamic bonus modifier (44). The game feature (42) additionally includes a motion indicator (65) associated with the dynamic bonus modifier (44), and during play a value of said dynamic award modifier is adjusted in relation to at least one parameter of a movement of the motion indicator (65). The bonus modifier (44) may be adjusted in concert with, or in response to, the parameter.
US08100759B2 Method and apparatus for providing player incentives
A system and method is provided for incentivizing players to visit a gambling location. In one aspect, a qualified person is invited to play an electronic game which has a plurality of outcomes, at least one of which is a winning outcome. In one embodiment, the qualified person may be required to redeem the outcome at the gambling location. In another embodiment, the person may be required to redeem the outcome at a redemption location. In another aspect, a method is provided for permitting a person to take one or more actions within a gambling location and in response inviting the person to play an electronic game separate from the games offered in a gambling environment at the gambling location.
US08100753B2 Systems, methods and articles to facilitate playing card games with selectable odds
A system and method may provide playing cards which are selected based on a desired set of payout or house odds and/or house advantage. The system and method may display payout odds for respective player positions. The system and method may operate a playing card handling device to provide the playing cards in a random or pseudo-random fashion, based at least in part on the selected payout or house odds and/or house advantage.
US08100752B2 Method, apparatus, and program product for presenting gaming results through inverse symbol logic
A method displays a number of symbol locations with a respective graphic symbol at each symbol location. Each symbol location may comprise an actual reel or simulated reel which is capable of displaying any one of a number of graphic symbols included in a group of presentation symbols. This group of presentation symbols includes a target symbol. In response to a first player input, each of the number of symbol locations is caused to conduct a respective symbol change process one or more times to change the graphic symbol included at each respective symbol location to a respective one of the graphic symbols included in the group of presentation symbols. The symbol locations all ultimately stop at the end of a game cycle to show a respective graphic symbol included in the group of presentation symbols, and an award may be presented to the player at the end of the game cycle depending upon the particular graphic symbols shown at the various symbol locations. According to the invention, at least some of the awards available in the game are based at least in part on the absence of the target symbol at one or more of the number of symbol locations.
US08100747B2 System and method of conducting an auction based game
A system and method for conducting a game including a first question and answer round (or alternatively, a physical challenge round) where a contestant can accumulate points and a second auction round where the contestant can bid on lots/prizes with the accumulated points. The system and method provide for presenting at least one of a mental or physical challenge to the at least two players; crediting a predetermined number of points to each of the at least two players based on an outcome of the challenge; auctioning at least one predetermined prized to the at least two players, the at least two players using the credited points to bid for the predetermined prize; and awarding the at least one predetermined prize to one of the at least two players with the highest bid.
US08100743B2 Polishing apparatus
A polishing apparatus is used for polishing a substrate such as a semiconductor wafer to a flat mirror finish. The polishing apparatus includes a polishing table having a polishing surface, a top ring body configured to hold and press a substrate against the polishing surface, a retainer ring provided at an outer peripheral portion of the top ring body and configured to press the polishing surface, and a retainer ring guide fixed to the top ring body and configured to be brought into sliding contact with a ring member of the retainer ring to guide a movement of said ring member. Either one of sliding contact surfaces of the ring member and the retainer ring guide which are brought into sliding contact with each other comprises a low friction material.
US08100741B2 Vibration device for a super finishing apparatus and an attachment tool comprising the vibration device
A vibration device for a super finishing apparatus for super finishing a mechanical object is disclosed. It comprises at least two sliding means (1, 3), each comprising a guide (5, 7) and an element (9, 11) provided with a through hole (13) for receiving the guide (5, 7), allowing a relative movement between the guide (5, 7) and the element (9, 11) provided with the through hole (13), and a movable structure (15) fixed to the at least two sliding means (1, 3). Further, each sliding means (1, 3) presents at least one liquid fluid inlet (19) allowing a liquid fluid to enter the through hole (13) and suspend the guide (5, 7) in relation to an inner surface of the through hole (13). An attachment tool comprising the vibration device is also disclosed.
US08100739B2 Substrate holding apparatus, polishing apparatus, and polishing method
A substrate holding apparatus prevents a substrate from slipping out and allows the substrate to be polished stably. The substrate holding apparatus has a top ring body for holding and pressing a substrate against a polishing surface, and a retainer ring for pressing the polishing surface, the retainer ring being disposed on an outer circumferential portion of the top ring body. The retainer ring includes a first member made of a magnetic material and a second member having a magnet disposed on a surface thereof which is held in abutment against the first member.
US08100737B2 Camisole
A camisole comprising a tubular garment intended to be worn over a bra having shoulder straps. The camisole includes left and right suspension members, e.g., hooks, for suspending the camisole from the bra straps.
US08100736B2 Simulated engine sound device for bicycles or the like
A housing supports a rotatable handle grip and is constructed to be received upon the end of a bicycle handlebar in place of a standard hand grip. The housing further supports a dial-type tachometer type readout. A gear drive within the housing responds to movement of the rotatable handle grip to produce tachometer readings. A sound producing device also responds to the handle grip movement to produce engine sounds.
US08100731B2 Electric connector, electronic device, and electrically-conductive touch method
An electric connector has a contact spring. The contact spring includes a fixed portion that is retained by a housing, an involute portion that is extended from the fixed portion into an inward spiral pattern, a revolute portion that is inverted from the involute portion and extended into an outward spiral pattern along the involute portion, an arm portion that is connected to a tail end portion of the revolute portion, a tangential direction of a portion connected to the revolute portion in the arm portion being aligned with a tangential direction of the tail end portion of the revolute portion, and a contact portion that is provided at a leading end of the arm portion to be projected to an outside of the housing, the contact portion abutting on the-other-end electrode to receive a pressing force in a direction in which the arm portion is substantially extended.
US08100730B2 Joint connector and wiring harness
A ground joint connector (JC) has a housing (20) with cavities (21) for receiving female terminals (11). The ground joint connector (JC) also has a joint terminal (50) including a male terminal portion (51) with male terminals (55) to be accommodated in the respective cavities (21). A bracket (52) is connected with the male terminal portion (51) and includes a mounting portion (65) to be mounted on a grounding portion. The bracket (52) extends in an extending direction of the cavities (21) from the rear edge of the male terminal portion (51) and then is bent twice to define a crank shape. Reinforcing flanges (73) and ribs (75) are formed on a flat portion at a base end side of the bracket (52). The housing (20) includes receiving portions (46, 47) for tightly holding back ends of the flanges (73) and the ribs (75).
US08100729B2 Cable connector and wiring assembly
A cable connector includes a connecting head, a wiring assembly and a cable. The cable is assembled with the wiring assembly, and then the wiring assembly is assembled with the connecting head, thereby forming a cable connector. The wiring assembly has a rear-half portion and a front-half portion that are connected to each other. The distal end of the rear-half portion is recessed to form a plurality of wiring ports. The interior of each wiring port is provided with a plurality of cable troughs. The cable troughs extend toward the front-half portion to form a plurality of wiring slots on the front-half portion.
US08100724B2 Electrical connector featured USB/eSATA interfaces
An electrical connector includes an insulating housing and contacts, the insulating housing defines a mating cavity and a tongue portion in the cavity, the tongue portion defines a first and a second mating face. A set of first contacts each defines a first contacting section disposed on the first mating face and a leg portion. A set of second contacts each defines a first contacting section disposed on the first mating face and a second contacting section bending from the first contacting section to be in the second mating face, a leg portion and a retention section connecting with the first contacting section and a the leg portion. A set of third contacts each defines a contacting section disposed on the second mating face and a leg section. The contacting portions of the third contacts are disposed at two sides of the second contacting sections of the second contact.
US08100719B2 Electronic device with grounding mechanism
A grounding mechanism is attached to a housing of an electronic device. The housing includes a receiving portion. The grounding mechanism includes an elastic member. The elastic member includes a main portion fixed to the receiving portion of the housing; a first bent portion and a latching plate extending from one side of the main portion, the first bent portion being in an acute angle with the main portion; and a second bent portion extending from another side of the main portion, the second bent portion having a projection.
US08100718B2 External SATA connector with data terminals and power-supply terminals on opposite sides of a terminal accommodating space or a terminal carrying part
An eSATA connector includes a connector plug and a mated connector receptacle. The connector plug includes a plug member, a plug metal housing, plug data terminals and a terminal holding part, in which the plug data terminals are held, and further includes plug power terminals held in the terminal holding part, wherein the plug power terminals and the data terminals each other electrically insulated.
US08100716B2 Electrical connector comprising a sealing mat
Electrical connector including a sealing mat made of a deformable material body having a thick portion and a thin portion having: an upper face a lower face parallel to the upper face, hollow passageways extending along a longitudinal axis from the upper face to the lower face, a housing including a receiving portion, a grid including a compression portion, the sealing mat being compressed between the receiving and compression portions.
US08100715B2 RCA-compatible connectors for balanced and unbalanced interfaces
A socket connector includes a conductive center receptacle, first outer socket contact having a first socket contact surface, second outer socket contact having a second socket contact surface, and non-conductive socket body. The socket contact surfaces are separated longitudinally along an axis of the receptacle. The socket body maintains the socket contacts electrically isolated from each other and the receptacle whenever the socket connector is not mated with a bi-conducting plug connector. A plug connector includes a conductive center pin, first outer plug contact having a first plug contact surface, second outer plug contact having a second plug contact surface, annular insulator, and non-conductive plug body. The plug contact surfaces are separated longitudinally along an axis of the pin. The plug body and insulator maintain the plug contacts electrically isolated from each other and the pin whenever the plug connector is not mated with a bi-conducting socket connector.
US08100713B2 Stacked electrical connector with a new type of spacer
An electrical connector includes a row of terminals arranged in the first direction and including contact portions and soldering tails, an insulative housing in which the contact portions of the terminal are arranged and behind which the soldering tails are arranged and a spacer securely attached to the housing to position the soldering tail. The spacer has a top face and a bottom face and a row of through holes running through the top face and the bottom face to receive the corresponding soldering tails thereof. Each of through holes includes a guiding hole communicating with the top face and a receiving hole communicating with the bottom face. The guiding hole defines guiding faces intersecting with the top face to form a frame intersection. The frame intersections are aligned in the first direction while the receiving holes are offset.
US08100711B2 Alignment assembly for electrical connectors
A high speed electrical connector assembly is disclosed providing a first subassembly having connector assemblies attached to a daughtercard, and a second subassembly having connector assemblies attached to a backplane. A keying guide module is mounted to the daughtercard and a keying guide pin is mounted to the backplane. The alignment of the keying guide module and keying guide pin aligns the connector assemblies on the daughtercard and backplane.
US08100710B1 Flash drive mounting apparatus having a base with a plurality of openings and two fixing members with hook-and-loop fasteners
A mounting apparatus is used to fix a flash drive mounted on a circuit board. The mounting apparatus includes a base, a first fixed member, and a second fixed member. The base includes a main body, a first fixed portion, and a second fixed portion. The first fixed member includes an opening, and a first hook-and-loop fastener. The first fixed member passes through the first fixed portion, and the opening for fixing the first fixed member to the base. The second fixed member includes two second hook-and-loop fasteners. Two ends of the second fixed member pass through the second fixed portion for fixing the second fixed member to the base. The first fixed member passes over the flash drive and fixes to the second fixed member by the first hook-and-loop fastener attached to one of the two second hook-and-loop fasteners for engaging the flash drive with a connector.
US08100709B2 Electrical connector having improved latching members
An electrical connector (100) for mating with a mating connector (700) along a mating direction includes an insulative housing (1) defining a passageway and a pair of latching members (2) inserted in the passageway. Each latching member has a resisting portion (21) and a latching portion (22) extending forwardly from the resisting portion and deformable from a first position to a second position for latching with the mating connector. The resisting portion includes an upper section (211) and a lower section formed at opposite sides of the latching portion and respectively abutting against the insulative housing along the mating direction when the latching portion is located in the second position.
US08100708B2 Connection structure for a vehicle
A connector has a first terminal housing with first connecting terminals aligned and accommodated therein, a second terminal housing with second connecting terminals aligned and accommodated therein, isolating plates and a connecting member. Each of the first connecting terminals and each of the second connecting terminals are surface-roughened such that a surface facing to other connecting terminal and composing a contact with the other connecting terminal provides a first frictional coefficient. When each of the isolating plates is adjacent to each of the first connecting terminals, each of the isolating plates is integrally fixed to each of the first connecting terminals, and when each of the isolating plates is adjacent to each of the second connecting terminals, each surface of the isolating plates facing to each of the second connecting terminals is surface-roughened to provide a second frictional coefficient.
US08100707B2 Plug contact pairing
A plug contact pairing comprises a plug pot with contact pins, as well as a plug head with contact circuits for connection of electrical line ends. A profiled ring (securing ring) is used to mount the plug head in an interlocking manner in the plug pot, is incorporated with a part of its cross section in a circumferential groove in the plug head and, during closure of the plug contact pairing, latches with the rest of its cross section into a groove on the internal circumference of the plug pot. By virtue of the shape and material of the securing ring and the slot shape, the plug head can be pulled out of the plug pot only with a tensile force which is greater than the limit value. In one development, the plug head is mounted with an identical connection in the plug housing, in which case the mounting ring connection is designed in comparison to the securing ring connection such that the tensile force with which the plug head can be pulled out of the plug pot is less than that by means of which the plug head is held in the plug housing by the mounting ring connection.
US08100704B1 Coaxial cable connector assembly
A coaxial cable connector assembly includes a bracket defining an upright locating plate and a horizontal holder plate, a coaxial cable connector fastened to the upright locating plate for the connection of a coaxial cable, and a grounding wire connector consisting of an externally threaded male connector member and an internally threaded female connector member and fastened to the horizontal holder plate to hold a grounding wire for discharging of magnetic waves, surge or shocks occurred during signal transmission through the coaxial cable to avoid system damage and to assure signal transmission stability.
US08100701B2 Adapter and plug-in connection system
A device which on the one side (socket side) includes a plug portion which may be inserted into the standardized plug socket. A plurality of chambers (15) is present on the other side (plug side), into which in each case a plug may be inserted. Moreover, the device has a plurality of adapter contacts which by way of introducing the plug portion into the socket, may be brought into electrical contact with the socket contacts. In each of the chambers, at least two of the adapter contacts are electrically conductively contactable by way of plug contacts of the introduced plugs. The chambers are at least partly present within the socket opening, i.e. the inserted plugs project into the socket opening, so that at least one piece of the plug lies within the socket opening.
US08100698B2 Electrical connector with removable housing
An electrical connector includes an insulative housing and a plurality of contacts received in the housing. Each contact includes a body portion, a spring portion and a soldering tail. The insulative housing includes a smooth top face, a plurality of generally parallel ridges extending from an opposite face to the top face to provide with interposed grooves between every adjacent ridges. The body portions of the contacts are individually engaged in the corresponding grooves and the spring portions extend forwards beyond a front face of the housing. The insulating housing includes a mounting face opposite to the smooth top face for confronting with a printed circuit board and the soldering tails extend downwards beyond the mounting face.
US08100697B2 Portable retractable erasable writing surface
A portable, retractable writing surface device provides a writing surface that may be extended from a housing and held sufficiently flat by the device to facilitate marking on the writing surface with a writing implement, such as a dry-erase marker, chalk, grease crayon, pencil, pen, permanent marker or the like. The device maintains sufficient rigidity in the extended writing surface, such that the device may be used without an additional support surface, such as a clip board or table. The writing surface may be retracted back into the housing to protect the writing surface and to reduce the size of the device for storage or transport, such as within a pocket or briefcase. Retracting the writing surface may include rolling the writing surface onto a spool, accordion folding the writing surface or otherwise reconfiguring the writing surface to make it fit into a compact space (collectively referred to herein as “compressing” the writing surface). One or more resilient members may be used to make the extended writing surface flat when the writing surface is extended from the housing. The writing surface may include a flexible computer display screen.
US08100691B2 Bar matrix
For a resilient mounting of a spider die onto a dental prosthetic suprastructure on a male spider mold, at least one retention element is molded onto a sleeve, and the retention element has a substantially occlusal alignment. The at least one retention element extends across the entire length of the sleeve and has a head having a connecting neck in its cross-section. In this manner, retention undercuts are formed on both sides of the connecting neck. The connecting neck of the at least one retention element is molded at an offset as opposed to the crown line of the sleeve. A spider die is thus created, which has an improved retention with an increased retention force at a smaller installation height.
US08100689B2 Safety connector for hot runner, having latch releasably interlocking valve stem with actuation plate
Disclosed is a safety connector for a hot runner having a valve stem and an actuation plate, the safety connector including: (i) a latch releasably interlocking the valve stem with the actuation plate so that in response to movement of the actuation plate, the valve stem becomes movable; and (ii) a latch mover being cooperative with the latch, and the latch mover being configured to move the latch responsive to a predetermined force acting on the valve stem so that so that the valve stem is released from the actuation plate.
US08100686B2 Tool for aiding resin distribution during the curing of composite material parts
The invention relates to a curing tool (11) for curing a composite material part formed by bundles of fibers embedded in a resin matrix in an installation, such as an autoclave, allowing the curing of the part by means of applying high pressures and/or temperatures, comprising at least one mechanical vibrating actuator (1) acting on the curing tool (11) itself to facilitate resin distribution in the part during the curing process.
US08100685B1 Imprint embossing alignment system
An imprint embossing alignment system. In one embodiment, the system includes a die having a bottom surface, an embossing foil positioned above the bottom surface, and a mandrel, to receive the substrate, having a rod portion that extends through a central portion of the die. The system also includes a ball bushing positioned around the rod portion and a ring portion positioned between the ball bushing and the embossing foil to hold a precise alignment of a centerline of the rod portion and a centerline of the embossing foil.
US08100681B2 Molding a battery
A mold for a battery, such as a secondary battery, and a method of molding a battery, such as a secondary battery, using the mold, uses a minimum amount of a molding substance, such as a resin, has its molding time shortened, and has a safety vent of a can being prevented from being fractured by high pressure during a molding process. Runners, through which a resin flows, are arranged parallel to cavities and the safety vent of the can is positioned closest to the gates, into which a resin is injected after the can and a protective circuit board are seated in the cavities. Due to the structure of the runners of the mold and the location of the safety vent of the can, the amount of resin used and the molding time are reduced. A fracture of the safety vent is avoided since a lower pressure occurs at the location closest to the gates during a resin filling process.
US08100680B2 Apparatus for manufacturing floor mat using double conveyor system
The present invention relates to a double-conveyor type apparatus for manufacturing a floor mat adapted to be disposed on a floor surface in an operating room in an industrial site, in various buildings or vehicles, or in an office room or house so as to reduce the impact or load transmitted to a human body and to prevent the sliding thereon, wherein the double-conveyor type apparatus includes a double-conveyor system having upper and lower conveyors formed of a plurality of unit upper and lower molds standardized to a given size and in series connected to each other is operated to allow a material of the floor mat to be passed thereon, thereby manufacturing the floor mat, such that the mass production of the floor mat can be simply and rapidly achieved to enhance the productivity.
US08100678B2 Tire vulcanizing machine
It is an object of the present invention to prevent or suppress the occurrence of a temperature difference between upper and lower portions of a green tire in a vulcanizing process carried out by a tire vulcanizing machine 1 and thereby stabilize the tire quality. The tire vulcanizing machine 1 comprises a tire vulcanizing bladder 20 disposed inside a green tire 4, a jet section 90 for jetting a heating/pressurizing medium to the interior of the bladder 20, a medium supply path for supplying the heating/pressurizing medium to the jet section 90, and a holding section 14 for holding an edge portion of the bladder 20, the edge portion being located on the side close to the medium supply path. Further, there are disposed heat insulators 7, 11, 8 and 6 so as to suppress the transfer of heat from the heating/pressurizing medium jetted from the jet section 90, to a lower edge portion of the green tire 4.
US08100676B2 Rotor, a method for producing such rotor and a pump comprising such rotor
The invention relates to a rotor for a positive displacement rotary pump. The rotor comprises a hub with an aperture and a center axis through aperture and at least 2 lobes radially extending from hub and in a direction essentially perpendicular to the axis of hub. The rotor comprises a core of a first polymer material and a cover of a second polymer material, which second polymer material has a hardness which is lower than the first polymer material. The first and the second polymer materials are connected to each other. The hub or the major part of the hub is preferably provided by the core, whereas at least a part of the lobes is provided by the cover. The invention also relates to a method of providing the rotor and a pump comprising the rotor.
US08100675B2 Fluid transporting device, and fluid transporter
A fluid transporting device comprises a tube frame having a tube guide wall for arranging a tube having an elasticity in an arcuate shape, and a rotary pressure mechanism having a plurality of rollers. The rotary pressure mechanism is arranged, when the tube is arranged in the tube frame, on the side opposite to the guide wall side of the tube, such that its center of rotation is aligned with the center of the arc of the tube guide wall. A plurality of push pins are interposed between the tube and the rotary pressure mechanism and are arranged radially of the center of rotation of the rotary pressure mechanism. A switching mechanism moves at least one of the rollers to a position for the push pins to release the tube and a position for the push pins to press the tube.
US08100672B2 Autonomous electrochemical actuation of microfluidic circuits
A microfluidic structure with an electrically controlled pressure source is shown. The pressure source is an electrolyte connected with electrodes. Dissociation of the electrolyte generates the pressure, which is used to obtain a valve-like or pump-like behavior inside the microfluidic structure. A process for manufacturing the microfluidic structure and a method to circulate fluids in a microfluidic channel are also described.
US08100670B2 Liquid propulsion device incorporating a pyrotechnic gas generator in the structure thereof
The subject of the present invention is a device (50) for propelling a liquid (L) comprising a reservoir (51) equipped with a mobile separation member (57) and a pyrotechnic gas generator (1), which is arranged inside said reservoir (51), equipped with nozzles (4a, 4b, 4a′, 4b′). Characteristically, said nozzles (4a, 4b, 4a′, 4b′) of said gas generator (1) are arranged radially on the wall(s) of said body (2) and said gas generator (1), arranged in such a way that its axis corresponds to the line of travel of said mobile separation member (57), is equipped with a deflector (8) to deflect said generated combustion gases (G) along said line of travel of said mobile separation member (57).
US08100664B2 Impeller for a cooling fan
An impeller (10) for a cooling fan includes a hub (20) having a circular wall (22) and an annular sidewall (24) extending upwardly from a periphery of the circular wall, and a plurality of blades (30) extending radially from the sidewall of the hub. Each of the blades includes a first portion (32) near the hub and a second portion (34) away from the hub, wherein each of the second portions has a pair of opposite ribs (36) formed on two lateral sides thereof, thereby reducing a noise level generated by the impeller when the impeller rotates.
US08100658B2 Axial-flow fluid machine blade
An axial-flow fluid machine blade which achieves reduction of the frictional loss of the blade and provision of a high surge-resistant property is provided. An axial-flow fluid machine blade 60 used for an axial-flow fluid machine includes a leading edge 61 projecting at the tip portion and the root portion thereof toward the upstream side and a trailing edge 62 projecting at the tip portion, the mid-span portion and the root portion thereof toward the downstream side.