| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 针对ERG致癌基因阳性癌症的新型抑制剂 | CN201580019407.1 | 2015-03-12 | CN106459601A | 2017-02-22 | 克利夫顿·达尔加德; 艾哈迈德·穆罕默德; 米拉·斯里瓦斯塔瓦; 希弗·斯里瓦斯塔瓦 |
| ERG基因改变是与包括前列腺癌的许多癌症相关的一些最突出基因组变化。所述癌症特异性改变导致野生型ERG蛋白或改变的ERG蛋白过度表达。本发明提供野生型ERG蛋白或改变的ERG蛋白表达的选择性抑制剂。因此，本发明的ERG抑制剂是用于治疗ERG阳性癌症的治疗剂。 | ||||||
| 2 | 喷墨用墨水、喷墨用墨水的制造方法、喷墨记录方法以及墨盒 | CN200580029083.6 | 2005-08-30 | CN101010394A | 2007-08-01 | 大角孝一; 须釜定之 |
| 一种喷墨用墨水，其至少含有色料，所述色料为C.I.食品黑2或C.I.直接黑195中的至少一种、以及下述通式(I)所表示的化合物或其盐。 | ||||||
| 3 | 喷墨用墨水、喷墨用墨水的制造方法、喷墨记录方法以及墨盒 | CN200580029083.6 | 2005-08-30 | CN101010394B | 2010-05-05 | 大角孝一; 须釜定之 |
| 一种喷墨用墨水，其至少含有色料，所述色料为C.I.食品黑2或C.I.直接黑195中的至少一种、以及下述通式(I)所表示的化合物或其盐。通式(I) | ||||||
| 4 | Light-fast colorant and composition containing the same | JP2003338029 | 2003-09-29 | JP2004115812A | 2004-04-15 | JON YONKYON; RYU SEUNG-MIN |
| <P>PROBLEM TO BE SOLVED: To provide a colorant imparted with light stability in its molecule itself by bonding a light-fast material inside a dye or a pigment, and to provide a composition containing the colorant. <P>SOLUTION: The light-fast colorant minimizes side effects of separately added light fastness improver by bonding a light-fast material to a conventionally used colorant, wherein long preservation stability of images are obtained when applying the composition containing the light-fast colorant to a printer toner or the like. <P>COPYRIGHT: (C)2004,JPO | ||||||
| 5 | Recording liquid | JP25275588 | 1988-10-06 | JP2666412B2 | 1997-10-22 | 浩 滝本; 富雄 米山 |
| 6 | JPH0557581B1 - | JP50338887 | 1987-06-04 | JPH0557581B1 | 1993-08-24 | YAMADA YASUYUKI; ITO NAOTO; NISHIZAWA ISAO; YAMAGUCHI TERUHIRO |
| 7 | Azo pigment | JP29843386 | 1986-12-15 | JPS63225661A | 1988-09-20 | FUJII AKIHIKO; KURIYAMA TAKAYOSHI; MATSUKAWA MASANORI; ISHIKAWA MITSURU |
| PURPOSE: To provide an azo pigment which does not stain non-image area on plates, has a high density and is transparent and whose hue migrates toward blue side, by adding a specific compd. to 2-hydroxynaphthalene-3-carboxylic acid. CONSTITUTION: A lake is formed from 90W99mol.% of a coupled product of a diazo compd. of p-toluidine-m-sulfonic acid with 2-hydroxynaphthalene-3- carboxylic acid and/or its metal salt and 1W30mol.% of a coupled product of a diazo compd. of p-toluidine-m-sulfonic acid with a 3-hydroxy-2-naphthamido- N-naphthalene derivative of formula (wherein R is H, an alkyl, an alkoxy, nitro or halogen) and/or its metal salt. COPYRIGHT: (C)1988,JPO&Japio | ||||||
| 8 | Water-soluble azo compound, manufacture and use thereof as dyestuff | JP15401681 | 1981-09-30 | JPS5787464A | 1982-05-31 | KURUTO ROOZENBUTSUSHIYU |
| 9 | Suiyoseisenryonoseiho | JP13355275 | 1975-11-06 | JPS5169522A | 1976-06-16 | DENISU ROBAATO ANESURII RIDOYA; TOREBAA JEIMUZU SUMISU |
| 10 | NOVEL INHIBITORS FOR ERG ONCOGENE POSITIVE CANCERS | PCT/US2015/020172 | 2015-03-12 | WO2015138722A1 | 2015-09-17 | DALGARD, Clifton; MOHAMED, Ahmed; SRIVASTAVA, Meera; SRIVASTAVA, Shiv |
Alterations to the ERG gene are some of the most prominent genomic changes associated with many cancers including prostate cancer. Such cancer specific alterations result in the overexpression of wild type ERG protein or an altered ERG protein. The present invention provides selective inhibitors of wild type or an altered ERG protein expression. The ERG inhibitors of the invention, therefore, are therapeutic agents for treating ERG positive cancers. |
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| 11 | インクジェット用インク、インクジェット用インクの作製方法、インクジェット記録方法及びインクカートリッジ | PCT/JP2005/016182 | 2005-08-30 | WO2006025562A1 | 2006-03-09 | 大角 孝一; 須釜 定之 |
| Disclosed is an inkjet ink containing at least a colorant which is composed of at least one of C. I. Food Black 2 and C. I. Direct Black 195, and a compound represented by the general formula (I) below or a salt thereof. | ||||||
| 12 | PEPTIDE LIGANDS THAT BIND TO SURFACES OF BACTERIAL SPORES | PCT/US1999/000771 | 1999-01-14 | WO99036081A1 | 1999-07-22 | |
| Peptides which bind to surfaces of bacterial spores have been identified by means of biopanning using phage-displayed peptide libraries. The sequences identified thereby are useful for binding studies to determine presence of spores in the environment or clinical setting. | ||||||
| 13 | PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY | PCT/JP1987000353 | 1987-12-17 | WO87007736A1 | 1987-12-17 | |
| A photosensitive material for electrophotography having high sensitivity and excellent durability, which comprises a photosensitive layer containing at least one of azo compounds having a tetraphenylthiophene or tetraphenylthiophene 1,1-dioxide skeleton. | ||||||
| 14 | Azo dye and intermediate, and their preparation and use | JP19770295 | 1995-08-02 | JPH08100130A | 1996-04-16 | HORUDEI BERENGEERU BARURA; HOSE ROKASU SORORURA |
| PROBLEM TO BE SOLVED: To provide a compd. which is a specific bis-(arylsulfonyl)amine and is used esp. as a coupling component for an azo dye useful for dyeing leather and to provide a mixture of the same. SOLUTION: A compd. of the formula: A-E-SO 2-NH-SO 2-E-A [wherein each E is independently a divalent arom. group; and each A is independently a heterocyclic group of formula I (wherein R 1 and R 2 are each a 2- or 3-membered linking chain and form, together with a group of formula II to which they are bonded, a 5- or 6-membered heterocyclic group; and C is a carbon atom capable of coupling with a diazonium)], and a mixture of the compounds are provided. Pref., E is a (substd.) phenynlene or naphthylene. Pref., A is a group selected from among pyrazolone and pyridone series and is present at the m- or p-position to SO 2. A pref. example of the compd. of the formula is represented by formula III (wherein R 3 is a 1-4C alkyl or carboxyl, pref. methyl), and the compd. of the formula is prepd. by reacting a compd. of formula IV (wherein n is 0 or 1) with a dicarbonyl compd., etc. COPYRIGHT: (C)1996,JPO | ||||||
| 15 | New black azo dye | JP6954891 | 1991-01-14 | JPH05311085A | 1993-11-22 | TANIGUCHI KOICHI |
| PURPOSE:To obtain a new black azo dye which is capable of high concentration dyeing under any dyeing conditions and does not cause the pollution of waste water by coupling a diazonium salt or a tetrazonium salt obtained by diazotizing or tetrazotizing a specified amine with an aminonaphthol derivative. CONSTITUTION:The dye is a disazo dye, a trisazo dye or a tetrakisazo dye comprising a compound obtained by diatotizing or tetrazotizing an amine of formula I (wherein Q is hydrogen, amino nitro or the like; omega is -N=N-, -SO2- or the like; R1 to R4 are each hydrogen, 1-4C alkyl or the like; and k is 0 or 1) and coupling the obtained diazonium salt or tetrazonium salt with a compound of formula II (wherein D is a group of formula III or the like; X is hydrogen, amino or the like; Y is hydrogen, 1-4C alkyl or the like; Z is hydrogen, 1-4C alkyl or the like; R8 to R10 are each hydrogen, 1-4C alkyl or the like; m is 0-2; and n is 1-4) and optionally converting the product into a copper complex, an inner salt, an acid addition salt, an alkali metal salt or an amine salt. | ||||||
| 16 | JPH0470344B2 - | JP12317781 | 1981-08-07 | JPH0470344B2 | 1992-11-10 | RAINHARUTO PEDORATSUTSUI |
| 17 | JPH0330630B2 - | JP10150682 | 1982-06-15 | JPH0330630B2 | 1991-05-01 | UDOO BERUKUMAN; GYUNTAA HANZEN; DEIITORITSUHI RATSUHA; MIHYAERU TOOMASU; GEORUKU TSUAIDORAA |
| 18 | Recording liquid | JP25275588 | 1988-10-06 | JPH0299571A | 1990-04-11 | TAKIMOTO HIROSHI; YONEYAMA TOMIO |
| PURPOSE: To provide a recording liquid outstanding in quick dryability after recording, typewritten letter quality, recording characteristics, storage stability, light resistance of recorded images, weatherability, etc., thus suitable for ink jet recording, writing utensils, etc., comprising an aqueous medium, a specific compound and PVA, etc. CONSTITUTION: The objective recording liquid comprising (A) an aqueous medium, (B) a compound of formula I (m and n are each 1 or 2; M is Na, K, Li or NH 4) (e.g., a compound of formula II), and (C) at least one kind of compound selected from PVA 200-1000 in polymerization degree and 80-90% in saponification degree, hydroxyethyl cellulose and (mono, di or tri)-ethanolamine acetic acid salts. COPYRIGHT: (C)1990,JPO&Japio | ||||||
| 19 | Colored oil composition | JP19014683 | 1983-10-11 | JPS6081268A | 1985-05-09 | OOTSUKA MASAHIRO |
| PURPOSE: The titled composition, containing a specific black disazo dye, having improved solubility in petroleum solvents, etc. and stability with time, and suitable for coloring petroleum products and writing utensils, etc. CONSTITUTION: A colored oil composition obtained by incorporating (A) a novel black disazo dye expressed by the formula [R is H or CH 3; R 1 and R 2 are H, 4W18C alkyl, alkenyl or (alkyl-substituted) benzyl, provided that R 1 and R 2 are not H at the same time] with (B) an aliphatic hydrocarbon based solvent and/or aicyclic compound based solvent as a petroleum solvent, e.g. (cyclo)hexane, or a halogenated hydrocarbon and if necessary a resin, etc. For example, the compound expressed by the formula (R is H; R 1 and R 2 are n-C 12H 25) is obtained by diazotizing 4-phenylazo-1-naphthylamine, and coupling the resultant diazo compound with 1,8-diaminonaphthalene. COPYRIGHT: (C)1985,JPO&Japio | ||||||
| 20 | Sulfonic acid group-containing dye | JP10150682 | 1982-06-15 | JPS57212256A | 1982-12-27 | UDOO BERUKUMAN; GIYUNTAA HANZEN; DEIITORITSUHI RATSUHA; MIHIYAERU TOOMASU; GEORUKU TSUAIDORAA |
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