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Reagent for detection of ursodesoxycholic acid and its preparation

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专利汇可以提供Reagent for detection of ursodesoxycholic acid and its preparation专利检索,专利查询,专利分析的服务。并且PURPOSE: To prepare a reagent for the detection of ursodesoxycholic acid useful for high accuracy hepatic function test, by forming a covalent bond between an enzyme and ursodesoxycholic acid in the presence of carbodiimide.
CONSTITUTION: Ursodesoxycholic acid is bonded with an enzyme, pref. alkaliphosphatase, through a covalent bond in the presence of a carbodiimide such as 1- ethyl-3-(3-dimethylaminopropyl)carbodiimide, to obtain a reagent for the detection of ursodesoxycholic acid. The average number of bonded ursodesoxycholic acid is pref. ≤25 per 1 molecule of the enzyme. Addition of magnesium chloride to the reagent is effective to prevent the lowering of enzymatic activity during storage.
COPYRIGHT: (C)1979,JPO&Japio,下面是Reagent for detection of ursodesoxycholic acid and its preparation专利的具体信息内容。

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