| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 61 | Method and apparatus for mapping pressure and tissue properties | US667765 | 1996-06-21 | US5749364A | 1998-05-12 | John W. Sliwa, Jr.; Michelle L. Jung; Paul E. Chandler; Amin M. Hanafy; David J. Napolitano |
| The invention disclosed relates to a novel method of mapping and presenting fluid pressure information within a living body utilizing changes in acoustic behavior of microbubbles situated in a bodily fluid such as blood. Differences in the returned acoustic spectra from the microbubbles are related by an algorithm to fluid pressure which is colorized and presented in a manner similar to Doppler imaging. In a further aspect of the invention, the work output of an organ such as the heart may computed from the blood pressure information in association with flow information obtained through Doppler related imaging, which then, is presented in a colorized fashion. In a still further aspect, an improved method of assessing the health of tissue is disclosed utilizing changes in the acoustic spectra of microbubbles infused in the tissue in response to palpitation. | ||||||
| 62 | Ultrasonic manometry process in a fluid by means of microbubbles | US806794 | 1991-12-12 | US5195520A | 1993-03-23 | Reinhard Schlief; Hans Poland |
| The invention relates to an ultrasonic manometry process in a fluid containing stabilized micro bubbles in an ensemble, wherein ultrasonic impulses are radiated into the fluid and brought to interact with the micro bubbles. The amplitude and/or frequency alterations in the ultrasonic scatter signals are recorded and evaluated compared with the ultrasonic impulses radiated in and/or previously recieved. Preparations for measuring blood pressure which can be used with the manometry process are described. | ||||||
| 63 | Blood vessel cannulation device | US765876 | 1991-09-26 | US5167630A | 1992-12-01 | Kamaljit S. Paul |
| This invention provides a cannulation device which is adapted for facilitating the location and venipuncture of a blood vessel with ease and precision. A carrier assembly supports a movable cubic block unit which contains an aligned combination of an ultrasonic probe and a cannula guide path means. The cubic block unit moves laterally within a defined space, whereby a blood vessel is located ultrasonically by by blood flow detection, and the guide path means assists venipuncture by a cannula. | ||||||
| 64 | Automatic arterial blood pressure recorder | US74363 | 1987-07-16 | US4790325A | 1988-12-13 | Arnold S. Lee |
| One aspect of the present invention involves a blood pressure recorder system of the type having an inflatable cuff, a pressurized gas source and an inflation valve. The system includes a cuff pressure trigger unit which senses the gas pressure in the cuff. When the duration of significant gas pressure in the cuff exceeds a predetermined time, the cuff pressure sensor facilitates relieving pressure in the cuff. The system also includes a safety system for insuring that the cuff pressure trigger unit is operative. The safety system is independent of changes in the input power.Also disclosed is an improved doppler ultrasonic blood pressure transducer and a novel method for automatically positioning a blood pressure transducer adjacent a skin surface. | ||||||
| 65 | Venous pressure measuring method and apparatus | US553951 | 1983-11-21 | US4566462A | 1986-01-28 | Herbert F. Janssen |
| Venous pressure is measured by monitoring blood flow in a vein with a Doppler probe, exerting pressure on the vein downstream of the probe with a cuff inflated at the rate of 10 mm Hg/second or more and recording the pressure at the instant blood flow stops. The cuff is immediately deflated. Measuring apparatus is also disclosed. | ||||||
| 66 | Apparatus for the automatic measurement of the arterial pressure of a patient | US719587 | 1976-08-30 | US4127114A | 1978-11-28 | Max Bretscher |
| This invention relates to an automatic apparatus for the measurement of the arterial pressure which comprises, within a casing, an ultrasonic emitter-receiver as well as a piezo-electric pressure detector. This casing houses also a measuring chamber partly limited at least by a supple and deformable wall intended to enter into contact with the patient. | ||||||
| 67 | Artifact rejection for blood pressure monitoring | US38080573 | 1973-07-19 | US3885551A | 1975-05-27 | MASSIE HAROLD LEE |
| Apparatus for automatically implementing indirect blood pressure measurement with transducer means for deriving and developing electrical signals in response to the interaction of blood pressure and cuff pressure under a varying external pressure capable of occluding an artery, and detector means for analyzing the electrical signals in terms of pulse width and rate for detection and rejection of artifact signals.
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| 68 | Blood flow pressure measurement technique employing injected bubbled and ultrasonic frequency scanning | US3640271D | 1969-06-30 | US3640271A | 1972-02-08 | HORTON JOHN W |
| A nonsurgical technique of measuring blood characteristics of pressure and flow by injecting minute gas bubbles into the bloodstream. The bubbles are subjected to a beam of ultrasonic radiation and flow is determined by detecting the resultant scattering which is indicative of the time taken for the bubble to pass between two points, while blood pressure is determined by varying the frequency of the ultrasonic beam to determine the resonant frequency of the bubbles which is proportional to pressure.
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| 69 | Blood pressure monitor | US3605723D | 1969-09-03 | US3605723A | 1971-09-20 | KING EUGENE; MASSIE HAROLD LEE |
| APPARTUS FOR AUTOMATICALLY IMPLEMENTING INDIRECT ARTERIAL BLOOD PRESSURE MEASUREMENT WITH A TRANSMITTERRECEIVER OPERATION FOR DERIVING DOPPLER SHIFTED INFORMATION DUE TO ARTERIAL WALL MOVEMENT UNDER EXTERNAL PRESSURE, BY OBSERVING AND SELECTIVELY MONITORING ELECTRICAL DOPLER SIGNALS REPRESENTATIVE OF THE INFORMATION THROUGH A FILTER ARRANGEMENT OPERATING IN A FIRST AND SECOND BRAND PASS FREQUENCY RANGE, WHERE THE SECOND BAND PASS FREQUENCY RANGE IS EMPLOYED INSTEAD OF THE FIRST ON THE BASIS OF CERTAIN CRITERION OBSERVED IN MONITORING THE ARTERIAL MOVEMENT.
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| 70 | Ultrasonic doppler body surface movement detector | US3601120D | 1969-04-14 | US3601120A | 1971-08-24 | MASSIE HAROLD LEE |
| A device for utilization with an ultrasonic system for internal exploration of living organisms, enabling improved measurement of low blood pressure values by audible monitoring including modulating an audible tone frequency with the signals to be detected to generate a distinct audible signal rhythm which can directly be detected by human ear and distinguished from noise.
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| 71 | Ultrasonic transducer assembly for biological inspections | US3552382D | 1968-01-11 | US3552382A | 1971-01-05 | MOUNT BRUCE ELSON |
| An ultrasonic search device and method for examining physical properties within an animal or a human body, including an array of ultrasonic transducers separably mounted on a supporting member constructed to conform with and be held against the curvature of a body area, for irradiating a selected section of a body with ultrasonic energy and focusing the reflected transmitted ultrasonic energy therefrom. Associated with the transducers may be separate lens means for coupling the transducers with the body and for direction of the ultrasonic energy. The ultrasonic search device can be employed for blood pressure monitoring by placement with an inflatable cuff applied about a body limb for detection of an artery to be occluded by cuff pressure variations.
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| 72 | Non-invasive in vivo pressure measurement | US97067 | 1998-06-12 | US6086533A | 2000-07-11 | Joseph R. Madsen; George A. Taylor |
| Apparatus and methods are disclosed for non-invasive measurement of blood velocity in otherwise inaccessible body regions, and for correlating such measurements with externally applied pressure to detect and/or assess diseases or physiological abnormalities. The blood velocity measurements can be based on the Doppler shift that occurs when an ultrasonic wave is scattered by moving particles within the blood. Since blood vessels have elastic walls, the geometry of the walls, and therefore the flow dynamics, will change in response to elevated in vivo pressure. The change in resistance to blood flow resulting from these pressure induced changes to the blood vessel wall geometry can provide a measure of intracranial pressure, ophthalmic pressure or various other body conditions that affect blood perfusion. Since the blood vessel wall geometry changes rapidly in response to such changes in pressure, the invention can be used to detect hydrocephalus, retinopathy, papilledema and other physiological abnormalities manifested by pressure changes. | ||||||
| 73 | Method for hemodynamic stimulation and monitoring | US926209 | 1997-09-09 | US5947901A | 1999-09-07 | Richard T. Redano |
| The present invention is directed toward a method for stimulating and/or monitoring hemodynamic activity, such as blood flow, in a penis. The method of the present invention comprises the coupling of an ultrasound source to the outer surface of the penis and transmitting ultrasound energy into the penis at a sufficient frequency and intensity to increase hemodynamic activity. An apparatus is also provided for practicing the method of the present invention. The apparatus provides for position adjustment of the ultrasound transducers during the circumferential expansion of the penis resulting from increased hemodynamic activity. | ||||||
| 74 | Apparatus for penile hemodynamic monitoring and ultrasound transmission | US149367 | 1998-09-08 | US5931783A | 1999-08-03 | Richard T. Redano |
| The present invention is directed toward a method and apparatus for transmitting ultrasound energy into an expanding penis and for stimulating and/or monitoring hemodynamic activity, such as blood flow, in a penis. The method of the present invention comprises the coupling of an ultrasound source to the outer surface of the penis and transmitting ultrasound energy into the penis at a sufficient frequency and intensity to increase hemodynamic activity. An apparatus is also provided for practicing the method of the present invention. The apparatus provides for position adjustment of the ultrasound transducers during the circumferential expansion of the penis resulting from increased hemodynamic activity. | ||||||
| 75 | Exciter-detector unit for measuring physiological parameters | US606563 | 1996-02-26 | US5904654A | 1999-05-18 | William J. Wohltmann; Mark H. Sher; Bryan F. Flaherty; Richard G. Caro |
| An exciter-detector unit is disclosed which includes an exciter and a detector mounted on a common support for inducing perturbations into the body and detecting the perturbations after they travel a distance through the body in order to detect a hemoparameter. | ||||||
| 76 | Process of continuous noninvasive hemometry | US327361 | 1994-10-11 | US5833602A | 1998-11-10 | Omoigui Osemwota |
| This invention relates to a process of determining continuously and non-invasively (without the withdrawal of blood.) the concentrations of hemoglobin. This is done by measurement of the path length and analysis of the pulsatile component of absorbance of multiple wave lengths of light transmitted through a tissue bed. This invention also relates to the process of simultaneous direct or indirect measurement of the pulsatile arterial width or arterial diameter which is equivalent to the pulsatile path length of the light transmitted across the tissue bed. Measurement of this arterial diameter or pulsatile path length is a prerequisite for non invasive determination of the hemoglobin, hematocrit or pigment concentrations in blood. | ||||||
| 77 | Ultrasonic sensors for monitoring the condition of a vascular graft | US949413 | 1997-10-14 | US5807258A | 1998-09-15 | George E. Cimochowski; George W. Keilman |
| A parameter indicative of the status of fluid flow is remotely monitored in a vessel, a natural graft, or a synthetic graft. One or more transducers are provided either in a wall of a synthetic graft or adjacent to a vessel or natural graft to monitor the parameter. A conformal array transducer or a tilted element is used to monitor fluid flow or velocity through the graft or vessel based on the effect of the fluid on ultrasonic waves produced by the transducers. The conformal array transducer comprises a plurality of elements that curve around the graft or vessel and are excited with an input signal provided by an implantable electronics circuit, producing ultrasonic waves that propagate into the fluid flowing within the graft or vessel. Transit time or Doppler measurements are made using an appropriate number of these transducer to determine either fluid flow or velocity. Various implantable electronic circuits are provided that enable a selected transducer to be driven and to receive an ultrasonic signal or a pressure signal indicative of the status of fluid flow monitored by the transducer. The implanted electronic circuit is connected to an implanted radio frequency (RF) coil. An external coil that is connected to a power supply and monitoring console is coupled to the implanted RF coil to convey power and receive data signals from the transducer that are indicative of the parameter being monitored. | ||||||
| 78 | Motion insensitive pulse detector | US700647 | 1996-08-14 | US5791347A | 1998-08-11 | Bryan P. Flaherty; Mark H. Sher; Richard G. Caro |
| A motion insensitive pulse detector for detecting a patient's pulse includes an exciter adapted to be positioned over a blood vessel of the patient and configured to induce a transmitted exciter waveform into the patient. A noninvasive sensor is adapted to be positioned over the blood vessel and configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of the hemoparameter containing a component of a received exciter waveform. A processor is coupled to the noninvasive sensor and configured to process the noninvasive sensor signal to determine the patient's pulse. Advantages of the invention include the ability to detect a patient's pulse even when the patient is moving or being moved by medical personnel. | ||||||
| 79 | Method and apparatus for non-invasively deriving and indicating of dynamic characteristics of the human and animal intracranial media | US115439 | 1993-09-01 | US5388583A | 1995-02-14 | Arminas Ragauskas; Gediminas Daubaris |
| An ultrasonic non-invasive technique is descried for deriving the time dependencies of characteristics of certain regions in the intracranium medium. Precise measurements of the transit travel times of acoustic pulses are made and processed to extract variable portions indicative of, for example, the pulsatility due to cardiac pulses of a basal artery or a cerebroventricle or the variation in the pressure of brain tissue, as well as changes in the cross-sectional dimension of the basal artery and ventricle. In one technique, the transit time variations attributable to cardiac pulses are extracted by processing higher harmonics in the frequency domain. Frequency and phase detection techniques are described. | ||||||
| 80 | Method for determining the arterial blood pressure in a non-invasive manner | US489038 | 1990-03-06 | US5099852A | 1992-03-31 | Jean J. Meister; Yanik Tardy |
| This method for establishing blood pressure in an artery employs the measurement results from two non-invasive sensors (5, 6) of artery diameter at two closely spaced locations (3, 4) separated by a distance .DELTA.x. The method provides for measuring the time spread .DELTA.t(7) between each pair of diameter measurements and establishing the propagation velocity of the pressure wave (9). Next, this value is compared with an expression (11) of the form c(D)= c(D, .alpha., .beta., .gamma., . . . ) which takes into account the physical behavior of the artery. This comparison permits one, following adjustment (12) based on a mathematical procedure for minimizing spreads, to calculate the parameters .alpha., .beta., .gamma., . . . of the relation given hereinabove. By replacing the parameters .alpha., .beta., .gamma., . . . by their values in a relation (10) D(p)= D(p, .alpha., .beta., .gamma., . . . ) and in employing the measurement results from a diameter sensor, one may deduce the blood pressure value p(t) at each instant of the cardiac cycle. The blood pressure value together with the corresponding value of the artery diameter permit tracing a pressure-diameter curve (14) by means of which the mechanical properties of the artery may be measured. | ||||||
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