最新美国发明专利第2025-03-04期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US12241062B2	Mammalian cells and methods for engineering the same The present disclosure provides mammalian cell lines for expression of viral vectors, and methods of making and using the same. Provided methods employ use of identifiers that are capable of being packaged into a viral vector to select and/or identify mammalian cell lines with engineered sequences associated with beneficial characteristics for viral vectors production. Exemplary viral vectors include AAV vectors.
US12241061B2	CAR library and scFv manufacturing method Provided are a CAR library used to screen scFvs that can be functional in CAR-T cells, and an scFv manufacturing method in which the CAR library is used. A chimeric antigen receptor (CAR) library of the present invention includes nucleic acids coding for first CARs. Each of the first CARs includes a first antigen-binding domain, a first transmembrane domain, and a first intracellular signaling domain. The first antigen-binding domain includes a first single-chain antibody (scFv) to be screened for the ability to bind to a target antigen. The first scFv includes a first heavy-chain variable region and a first light-chain variable region. The first heavy-chain variable region and the first light-chain variable region meet a predetermined condition.
US12241060B2	Methods, compositions, and systems for capturing probes and/or barcodes Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.
US12241058B2	Recombinant microbial system for directed evolution of glycocins and method of preparation thereof The present invention relates to a recombinant microbial system for generation of neo-glycocins, a substrate and to co-evolve its glycosyltransferase enzyme. The recombinant microbial system comprises a gene cassette A encoding for microbial O- and S-glycosyltransferase and its suitable acceptor substrate in conjugation with a cleavable dual affinity tag under the control of two independent inducible promoters. The gene cassette is expressed in a microbial host such as E. coli for the co-expression of glycosyltransferase and its suitable acceptor substrate. The invention further discloses method for production and bioactivity guided screening of O- and or S-neo-glycocins using the recombinant microbial system. The system provides optimized construct design, and methods for high yield production of glycocins and neo-glycocins for downstream applications.
US12241055B2	Bacterium degrading microorganism, microbial preparation, and method and device for degrading microorganism Provided are a bacterium having a 16S rRNA gene comprising a nucleotide sequence having 98.2% or more identity to the nucleotide sequence represented by SEQ ID NO: 1, and having an ability to degrade a target microorganism, a microbial preparation for degrading a target microorganism, comprising a bacterium (a1), and a method for degrading a target microorganism and a device for degrading a target microorganism using the same. Bacterium (a1) is a bacterium having a 16S rRNA gene comprising a nucleotide sequence having 90% or more identity to the nucleotide sequence represented by SEQ ID NO: 1, and having an ability to degrade a target microorganism.
US12241053B2	Modulation of novel immune checkpoint targets Dysfunctional or exhausted T cells arise in chronic diseases including chronic viral infections and cancer, and express high levels of co-inhibitory receptors. Therapeutic blockade of these receptors has clinical efficacy in the treatment of cancer. While co-inhibitory receptors are co-expressed, the triggers that induce them and the transcriptional regulators that drive their co-expression have not been identified. The immunoregulatory cytokine IL-27 induces a gene module in T cells that includes several known co-inhibitory receptors (Tim-3, Lag-3, and TIGIT). The present invention provides a novel immunoregulatory network as well as novel cell surface molecules that have an inhibitory function in the tumor microenvironment. The present invention further provides the novel discovery that the transcription factors Prdm1 and c-Maf cooperatively regulate the expression of the co-inhibitory receptor module. This critical molecular circuit underlies the co-expression of co-inhibitory receptors in dysfunctional T cells and identifies novel regulators of T cell dysfunction.
US12241051B2	Method for forming a porous cell substrate This disclosure describes methods and apparatuses for creating or using a fibrous cell substrate that is formed in a mold using temperature and wettability gradients and that upon which cells can be grown. The disclosed method can include utilizing a temperature gradient and a wettability gradient within a mold to form a porous cell substrate. In particular, the temperature and wettability gradients control nucleation and growth of crystals within the cell substrate solution to form parallel layers of cell substrate. The crystals can be sublimated by freeze drying and the porous cell substrate is seeded. More specifically, the disclosed method includes using pressure and an increased cell mixture viscosity to seed cells deep within the cell substrate. This disclosure also describes an apparatus for forming the structured porous cell substrate.
US12241049B2	Multi-compartment device containing human three-dimensional (3D) microtissues for toxicity testing This dual-compartment liver co-culture system exposes target microtissue to metabolites, allowing for evaluating toxicity using a standard multi-well plate for high throughput analysis. Discovery scientists can rapidly select lead compounds with desirable metabolic profiles, while safety scientists can determine the safety of drugs, pesticides, and environmental chemicals. This platform is allometrically scalable, so it can mimic the natural size differences between healthy organs and, with the liver, produce sufficient quantities of metabolites. The device is simple to use and designed for immediate in vitro pathology assessment using confocal microscopy, transcriptomics, and proteomics.
US12241047B2	Systems and methods for the preparation of ethanol-containing beverages using microorganisms The present inventive concept relates generally to simulating the barrel aging or finishing process of alcohol-containing products in a rapid manner using various microorganisms to impart flavors and aromas during the aging or finishing process. Products and methods used in the process of aging or finishing the alcohol-containing products are also provided.
US12241045B2	Detergent compositions and uses thereof The present invention relates to polypeptides having hexosaminidase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US12241043B2	Active composition delivery system An active composition delivery system having a water-soluble top layer, a water-soluble bottom layer, and an active composition disposed therebetween. The water-soluble top and bottom layers are joined together to form a pouch sized and shaped to hold an amount of an active composition. The active composition delivery system further includes a plurality of water-soluble joints, joining the top and bottom water-soluble layers.
US12241038B2	Polyalphaolefin phenols with high para-position selectivity The present disclosure provides a detergent additives and methods for preparing a sulfurized alkyl phenate product from polyalphaolefins.
US12241026B2	Process for the synthesis of high-value, low carbon chemical products The present invention describes improved processes for the synthesis of high value chemical products from low carbon syngas. In one aspect, a process for the production of chemicals is provided. The process comprises the following: feeding a feedstock comprising hydrogen and carbon monoxide to a liquid fuel production reactor, wherein the liquid fuel production reactor comprises a catalyst, thereby producing a product, wherein the product comprises a liquid phase and a solid phase, and wherein the liquid phase comprises C5-C23 hydrocarbons and oxygenated hydrocarbons, and wherein the solid-phase comprises C24-C45 aliphatic hydrocarbons, and wherein the liquid phase is between 51 percent by volume and 99 percent by volume of the product.
US12241020B2	Method and applications of nonstoichiometric ionic emulsions Methods are disclosed for synthesizing ionic liquid formulations using non-stoichiometric hydrophobic or hydrotropic ionic liquids, including aprotic or protic ionic liquids, to create emulsions, microemulsions, or nanoemulsions. Additionally, the provided ionic liquid formulations may be used to make surfactant-free or detergentless microemulsions or nanoemulsions that may be used as additives for aqueous or oil-based solutions. Methods for introducing an ionic liquid in an injection fluid into a reservoir via an introduction well area also provided. The injection fluid intermingles with reservoir fluid and the intermingled injection fluid and reservoir fluid is retrieved via a production well. Methods for introducing an ionic liquid in an injection fluid may be used for CO2 sequestration within a reservoir. The CO2 may be introduced concurrently or by alternating injections of CO2.
US12241018B2	High thermal coefficient slurry compositions and methods therefor A high-thermal conductivity slurry composition is contemplated that includes a slurry mixture comprising a high-thermal k material, water, and an optional dispersant. Preferably, the high thermal k material is in the form of a plurality of particles having a wide size distribution that spans across at least 2 log units and is present in an amount effective such that the slurry composition has, upon compaction or settling of the slurry mixture at a target location, a thermal conductivity of at least 3 W/m° K.
US12241016B2	High temperature high salt low end rheology modifiers A low-end rheology modifier for adjusting rheological characteristics of water-based drilling fluid systems, particularly for high salt, high density drilling fluids in high temperature and high-pressure applications. The low end rheology modifier comprises a copolymer and laponite clay, the copolymer comprising tert-Butylacrylamidosulfonic acid (TBAS) and n-vinylpyrrolidone (NVP) crosslinked with N,N′-Methylenebis(acrylamide).
US12241012B2	Heterocyclic compounds for liquid crystals Compounds of formula I liquid crystal media containing these compounds, and high-frequency components containing these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas, phased array antennas, and devices containing these components, and furthermore optical components containing these liquid-crystalline media, operable in the infrared region of the electromagnetic spectrum.
US12241011B2	Polyamine-polyesters as corrosion inhibition Compounds, compositions and methods are provided for reducing, inhibiting, or preventing corrosion of a surface, using a polyester polyamine compound. The polyester polyamine compound having a structure corresponding to Formula 1 or 2, or a salt thereof: wherein R1 is independently alkylene; R2 is independently hydrogen or —COR4; R3 is independently alkyl, alkenyl, aryl, or alkaryl; R4 is independently alkyl or alkenyl; R10 and R11 are each independently hydrogen, alkyl, or alkaryl; m is an integer from 1 to 10; n is an integer from 3 to 10; and wherein at least one R2 is —COR4.
US12241001B2	Systems for priming and adhesion of flooring The invention relates to layer structures containing polyaspartic primers (AG) and curable compositions based on silane-modified polymers (KS), and to a method for adhesion of flooring onto pre-treated substructures.
US12240997B2	Rheology control agent and paint composition A rheology control agent contains a reaction product of a polyisocyanate compound (a1), a primary monoamine having a number average molecular weight of 300 or less (a2), and a polyether amine having two or more amino groups and having a number average molecular weight of 1000 or more and less than 6000 (a3), wherein the proportion of the polyether amine having a number average molecular weight of 1000 or more and less than 6000 (a3) is within the range of 10 to 30 mass % based on the total amount of the components (a1) to (a3).
US12240993B2	Article with water and oil repellent layer To provide an article with a water and oil repellent layer, which is excellent in friction resistance.The article with a water and oil repellent layer of the present invention comprises a substrate, a water and oil repellent layer consisting of a hydrolyzed condensation product of a compound represented by the formula [A-(OX)m-]jY1[—Si(R)nL3-n]g, and a silicon oxide layer containing alkali metal atoms that exists between the substrate and the water and oil repellent layer, wherein the average value of the concentration of alkali metal atoms in a predetermined area in the silicon oxide layer is at least a predetermined value. In the formula, X is a fluoroalkylene group, m is at least 2, j, g, and k are at least 1, and Y1 and Y2 are linking groups, R is a monovalent hydrocarbon group, L is a hydrolyzable group or hydroxy group, n is 0 to 2, A is a perfluoroalkyl group or —Y2[—Si(R)nL3-n]n. When A is —Y2[—Si(R)nL3-n]k, j is 1, and when A is a perfluoroalkyl group and j is 1, g is at least 2.
US12240989B2	Organomodified metal oxide or metalloid oxide polymer film The present invention relates to a process for preparing a thin film on a substrate comprising the steps of preparing two precursor compositions comprising metalloid compounds and combining them thereafter whereby one precursor composition is hydrolyzed prior to combination. The present invention is further related to a multilayer structure and an article comprising the thin film obtainable by the process, a composition comprising the precursor compositions, a kit-of-parts comprising the precursor compositions and the use of the composition and the kit-of-parts for preparing a thin film on a substrate.
US12240988B2	Coating composition and laminate Provided is an aqueous coating composition capable of forming a fluororesin coating film layer with excellent electrical properties and surface physical properties, and good adhesive properties. A coating composition containing 2 or more kinds of fluororesins, where at least 1 kind of the fluororesin, a fluororesin (I), has a number of functional groups of 30 to 1,000 per 106 main-chain carbon atoms, and where the coating composition further contains an inorganic filler, a surfactant, and a liquid medium.
US12240986B2	Thermally curable ink-jet ink A thermally curable ink-jet ink includes a compound having a thermally curable functional group and a gelling agent. The thermally curable ink-jet ink undergoes a sol-gel phase transition depending on temperature.
US12240985B2	Ink for ink-jet printer of charge control type The purpose of the present invention is to provide an ink for ink-jet printers, the ink being able to be reduced in the content of an electroconductive agent and having low resistance. The ink for ink-jet printers of a charge control type according to the present invention, which is provided in order to overcome the problem, is characterized by comprising a resin, a pigment, an electroconductive agent, and a nonaqueous solvent, the electroconductive agent having a salt structure which generates an anion and a cation in the nonaqueous solvent, the anion having a trifluoromethylsulfonyl group and the cation being a quaternary ammonium cation or having an unsaturated heterocyclic structure.
US12240984B2	Process for preparing an aqueous gel ink with fixed color comprising silver or gold nanoparticles The invention relates a process for preparing an aqueous gel ink with fixed color comprising the following steps: (i) preparing a gel-based matrix of aqueous ink; (ii) preparing an aqueous suspension of gold or silver nanoparticles with a fixed color; (iii) adding the aqueous suspension of gold or silver nanoparticles obtained in step (ii) to the gel-based matrix of aqueous ink obtained in step (i).
US12240974B2	Method of making thermoplastic polyolefin A thermoplastic polyolefin (TPO) powder is provided. The TPO powder includes an olefin-block copolymer (OBC), polypropylene copolymer, an adhesion promoter, a sulfur-free stabilizer additive, a composition including a non-migratory hindered amine light stabilizers (HALS) and a color pigment, and talc. A TPO material formed from the TPO powder and methods of making the TPO powder and TPO material are also provided.
US12240973B2	Endoluminal device and polymer Various embodiments relate to compositions for use in endoluminal devices and to methods of using compositions in endoluminal devices. The compositions include two parts, a first part including a first solution and a second part including a second solution, wherein the first solution comprises one or more pre-polymers, a non-aqueous solvent, a polymerization co-initiator or initiator and optionally one or more chain extenders and additives, and the second solution comprises a polymerization initiator or co-initiator, a non-aqueous solvent and optionally one or more chain extenders and additives.
US12240962B2	Hydrogenated conjugated diene polymer, polymer composition, crosslinked body and tire A hydrogenated conjugated diene-based polymer which has a structure formed by bonding a nitrogen-containing compound having two or more alkoxysilyl groups and two or more nitrogen atoms with a plurality of conjugated diene-based polymer chains, wherein: when a composition ratio (molar ratio) in the hydrogenated conjugated diene-based polymer of each of a structural unit represented by formula (1), a structural unit represented by formula (2), a structural unit represented by formula (3), and a structural unit represented by formula (4) is p, q, r, and s, respectively, a value a represented by formula (i) is 0.80 or more and 0.97 or less, and an equilibrium storage modulus E′ of the hydrogenated conjugated diene-based polymer is 2.4 MPa or more, α=(p+(0.5×r))/(p+q+(0.5×r)+s) (i)
US12240960B2	Thixotropic agent for curable compositions A thixotropic agent for increasing the yield point of a curable composition, wherein the thixotropic agent includes (i) at least one urea compound from the reaction of at least one isocyanate with at least one amine and (ii) at least one polyether having blocked hydroxyl groups. The thixotropic agent is preparable in a simple manner and forms a spreadable paste which is firm at room temperature. It is particularly suitable as a constituent of moisture-curing polyurethane or SMP compositions, giving a good increase in the yield point thereof, without adversely affecting storage stability or migration characteristics. It enables phthalate-free adhesives, sealants or coatings that have surprisingly good conveyability coupled with a high yield point, and do not cause any problems with odor or fogging.
US12240958B2	Expandable graphite flame retardant layer for polyurethane and latex foam A flexible foam composition includes a flexible foam body having a surface, which flexible foam is polyurethane and/or latex flexible foam, and an expandable graphite layer on the surface or within the foam surface adjacent to the surface. The flexible foam composition with the expandable graphite layer imparts improved flame retardant properties to the composition.
US12240957B2	Method for fabricating impermeable porous particles A method for preparing core/shell particles includes forming a suspension of ethylenically unsaturated monomer droplets containing one or more monomers and a porogen in an aqueous medium containing a first stabilizer and a polymerization initiator, wherein at least one of the monomers is a cross-linking monomer, and wherein the first stabilizer is an inorganic colloid. The method further includes polymerizing the one or more monomers to form core/shell particles having a core of a porous polymer and a polymeric shell having a shell thickness of at least 5 nm, wherein any pores in the polymeric shell have a diameter of less than 2 nm.
US12240955B2	Method for producing composition for melt processing A method for producing a poly(3-hydroxybutyrate) resin-containing composition for melt processing includes: heating a material containing a poly(3-hydroxybutyrate) resin to a temperature equal to or higher than a melting point peak temperature in differential scanning calorimetry analysis of the poly(3-hydroxybutyrate) resin and equal to or lower than a melting point peak end temperature in the differential scanning calorimetry analysis of the poly(3-hydroxybutyrate) resin, wherein the difference between the melting point peak temperature and the melting point peak end temperature of the poly(3-hydroxybutyrate) resin is 10° C. or more; and extruding the heated material to obtain a composition for melt processing that has a new crystallization peak at a temperature higher than the melting point peak temperature.
US12240952B2	Methods and compositions for films, masterbatch, yarns, fabrics, and articles comprising same In one aspect, the disclosure relates to cooling films comprising a substrate and one or more cooling materials deposited on the substrate. The disclosed cooling films can be used to prepare the disclosed cooling masterbatch materials. The disclosed cooling masterbatch materials can be used to prepare disclosed cooling yarns. The one or more cooling materials deposited on the substrate of a disclosed cooling film, dispersed in a disclosed cooling masterbatch material, or in disclosed cooling yarn are nano-sized particles. In still further aspects, the present disclosure pertains to a fabric comprising a disclosed cooling yarn. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
US12240950B2	Polymer composition for improved grade plastics from recycled material A polymer composition of: a. 50-96 wt % of a recycled polypropylene; b. 4-50 wt % of talcum; e. 0-10 wt % of additives; wherein the additives are PEs, PE-MAs, PP-MAs, stabilizers, peroxides, CaOs or colorants; wherein the talcum has a D50 of less than 4 micron (ISO13317-3) and wherein the wt % is relative to the total weight of the polymer composition 50-90 wt % of a recycled polypropylene.
US12240948B2	Remoldable shape memory bismaleimide resin and use thereof A method of preparing a remoldable shape memory bismaleimide resin includes blending 2-allylphenyl glycidyl ether and adipic acid in acetonitrile, carrying out an esterification reaction under the condition of quaternary ammonium salt as a catalyst to obtain bis(3-(2-allylphenoxy)-2-hydroxypropyl)adipate containing a reversible dynamic group; then uniformly mixing bis(3-(2-allylphenoxy)-2-hydroxypropyl)adipate and bismaleimide, curing to obtain the remoldable shape memory bismaleimide resin. The prepared remoldable shape memory bismaleimide resin is not only excellent heat resistance and mechanical properties, but also can be remolded under hot pressing conditions. The method of preparing the remoldable shape memory bismaleimide resin has the advantages of wide raw material sources and simple process, and has a wide application prospect in the fields of aerospace, transportation, electronic information, new energy, insulated electrical industry and the like.
US12240947B2	Flame-retardant semi-aromatic polyamide and preparation method thereof The invention discloses a flame-retardant semi-aromatic polyamide derived from the following monomers: a diacid monomer A: where A1 is terephthalic acid or terephthalic acid and other diacid, terephthalic acid accounts for 50 to 100 mol % of A1, and A2 is [(6-oxido-6H-dibenzo-(c,e)(1,2)-oxaphosphorin-6-ketone)-methyl]-butanedioic acid, A1+A2=100 mol %, A1=90 to 99 mol %, A2=1 to 10 mol %; and diamine monomer B: one or more of diamine monomers containing 4 to 36 carbon atoms. In the present invention, by an in situ polymerization, a specific flame-retardant monomer [(6-oxido-6H-dibenzo-(c,e)(1,2)-oxaphosphorin-6-ketone)-methyl]-butanedioic acid is copolymerized in a semi-aromatic polyamide chain segment, excellent mechanical properties and low water absorption can be obtained.
US12240945B2	Compound, resin, polycarbonate resin, and optical molded article Provided is a compound represented by General Formula (1) in General Formula (1), Ar1 and Ar2 independently represent a group selected from the following Formulae,
US12240944B2	Optical lens The invention provides an optical lens that can provide small-sized imaging modules. The optical lens of the invention comprises a thermoplastic resin having a refractive index (nD) and Abbe number (ν) satisfying the following mathematical formula (A): nD≤−0.02×ν+2.040 (A) (where 1.660
US12240943B2	Continuous process for producing polyol modified polyalkenylene terephthalate The present invention relates to a continuous process for the production of polyol modified polyalkenylene terephthalates and the application of such polyol modified polyalkylene therephtalate on wire enamels.
US12240941B2	Rosin-based polymer for stain-blocking coating compositions A shellac-substitute is described herein in the form of an acid-functional polymer or an acid-functional polyester polymer. The acid-functional polyester polymer, among other uses, is suitable for stain-blocking with coating compositions, such as primers, sealants, stain-blocking coating compositions, odor-blocking compositions, and/or varnishes.
US12240939B2	Leading edge protection composition and uses thereof A polyurethane elastomer composition includes a polycarbonate diol and an aliphatic isocyanate, and lacking any solvent. The composition is used for leading edge protection (LEP), preferably of wind turbine rotor blades.
US12240932B2	Photocurable hydrophilic polymer, and coating composition, hydrophilic lubricating coating and article based on the same A photocurable hydrophilic polymer, coating composition and hydrophilic lubricating coating based on the same are provided. The photocurable polymer is formed by copolymerization of a polymerizable photosensitive monomer and a hydrophilic monomer. The photosensitive monomer comprises: 1) units containing a photosensitive structure; 2) units containing a tertiary amine co-initiator structure; and 3) units containing and unsaturated bond. The units containing the photosensitive structure are at least connected with the units containing the tertiary amine co-initiator structure through —OC(═O)—, and the units containing the unsaturated bond structure are connected with the units containing the photosensitive structure through the units containing the tertiary amine co-initiator structure. The photocurable hydrophilic polymer has a high photocurable efficiency, a simple preparation process, a high production efficiency, less environmental pollution, and hardly any cross-linking. By curing the coating composition, a hydrophilic coating with high firmness, high lubricity, excellent biosafety and compatibility can be obtained.
US12240927B2	Unimodal polyethylene copolymer and film thereof A unimodal ethylene-co-1-hexene copolymer that, when in melted form at 190 degrees Celsius, is characterized by a unique melt property space defined by combination of melt elasticity and complex viscosity ratio (shear thinning) properties. A blown film consisting essentially of the unimodal ethylene-co-1-hexene copolymer. A method of synthesizing the unimodal ethylene-co-1-hexene copolymer. A method of making the blown film. A manufactured article comprising the unimodal ethylene-co-1-hexene copolymer.
US12240923B2	Suspension process for preparing ethylene polymers comprising work-up of the suspension medium A process for preparing an ethylene polymer in a suspension polymerization including the steps of separating the formed suspension of ethylene polymer particles in a solid-liquid separator into wet ethylene polymer particles and mother liquor, transferring a part of the mother liquor into a work-up section including an evaporator for producing a wax-depleted portion of the mother liquor, a diluent distillation unit for producing isolated diluent from the wax-depleted portion of the mother liquor, and a wax removal unit operated by direct steam distillation for producing a gaseous hydrocarbon/steam mixture which is condensed and then separated into an aqueous phase and a hydrocarbon phase, wherein a first part of the hydrocarbon phase is transferred to the diluent distillation unit without passing the evaporator for producing the wax-depleted portion of the mother liquor.
US12240922B1	Transition metal complex assisted green hydrolysis for nanocellulose extraction The present disclosure relates to an improvement in the process of hydrolysis of cellulose to produce nanocellulose using imidazolium-based ionic liquids with short alkyl chains in the presence of transition metal complex and an oxidizing agent.
US12240920B2	Cyclic peptidomimetic for the treatment of neurological disorders The present invention provides to compositions and methods useful in the treatment of neurological disorders including, but not limited to, Angelman syndrome, depression, traumatic brain injury, stroke, and Alzheimer's disease. CN2097, a rationally designed cyclic peptidomimetic drug that has been demonstrated to have effectiveness in preclinical models for the treatment of neurological disorders, is rapidly cleared and has a short half-life. The present invention provides a stable analog of CN2097.
US12240919B2	Method for supporting thiol group-including compound The objective of the present invention is to provide a method for efficiently supporting a thiol group-including compound on an insoluble base material. The method for supporting a thiol group-including compound on an insoluble base material according to the present invention is characterized in comprising Step A: treating the thiol group-including compound with a thiol group-including organic reducing agent and an inorganic reducing agent, and Step B: contacting a reaction liquid of said Step A with the insoluble base material.
US12240914B2	Antibody against factor XIa in activated form of coagulant factor XI, preparation method therefor and use thereof Provided in the present application are an antibody against factor XIa in the activated form of coagulant factor XI, a preparation method therefor and the use thereof. The CDR of the heavy chain variable region of the antigen-binding fragment of the antibody comprises the amino acid sequence shown in SEQ ID NOs: 1-3, and the CDR of the light chain variable region thereof comprises the amino acid sequence shown in SEQ ID NOs: 4-6. The antibody can specifically bind to FXIa but not to FXI, and has the effect of inhibiting the endogenous pathway of human coagulation without affecting the exogenous pathway thereof, which can significantly inhibit the formation of arteriovenous shunt thrombosis, but does not increase the bleeding time and volume. Same has the potential to become an antithrombotic drug.
US12240909B2	Human antibodies to human interleukin 18 receptor alpha or beta Provided are antibodies or fragments thereof having binding specificity to anti-IL-18 receptor alpha or beta. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer and inflammatory and autoimmune diseases are also provided.
US12240906B2	Monoclonal antibodies to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) The present invention provides CTLA-4 monoclonal antibodies, particularly humanized monoclonal antibodies specifically binding to CTLA-4 with high affinity. The present invention also provides functional monoclonal antibodies cross-reactive to CTLA-4 of human, cynomolgus monkey and mouse. The present invention further provides amino acid sequences of the antibodies of the invention, cloning or expression vectors, host cells and methods for expressing or isolating the antibodies. The epitopes of the antibodies are identified. Therapeutic compositions comprising the antibodies of the invention are also provided. The invention also provides methods for treating cancers and other diseases with anti-CTLA-4 antibodies.
US12240900B1	Nucleic acids, vectors, and cells that encode antibodies and other proteins that bind folate receptor alpha This disclosure describes nucleic acids that encode proteins that specifically bind human folate receptor alpha (FRalpha) with high affinity. These proteins include a recombinant human anti-FRalpha IgG1 that is suitable for use as a therapeutic antibody to treat cancers that express FRalpha. Other FRalpha-binding proteins are also described including antibody fragments, antibody conjugates, and fusion proteins.
US12240898B2	Monoclonal anti-IL-1RAcP antibodies Monoclonal antibody that specifically binds IL-1RAcP, or an antigen binding fragment thereof, comprising: a) a heavy chain variable region (VH) comprising CDR1H, CDR2H and/or CDR3H, wherein the CDR1H region comprises an amino acid sequence selected from the group of SEQ ID NO: 155-231, wherein the CDR2H region comprises an amino acid sequence selected from the group of SEQ ID NO: 232-308, and wherein the CDR3H region comprises an amino acid sequence selected from the group of SEQ ID NO: 309-385; and b) a light chain variable region (VL) comprising CDR1L, CDR2L and/or CDR3L, wherein the CDR1L region comprises an amino acid sequence selected from the group of SEQ ID NO: 386-462, wherein the CDRL2 region comprises an amino acid sequence selected from the group of SEQ ID NO: 463-539, and wherein the CDR3L region comprises an amino acid sequence selected from the group of SEQ ID NO: 540-616 The monoclonal antibody is characterized in that it inhibits IL-1RAcP induced NFkB activity, useful in treatment of IL-1RAcP related diseases.
US12240896B2	Gremlin-1 inhibitor for the treatment of a bone fracture or bone defect The present invention relates to methods for the treatment of a bone fracture or bone defect. The invention discloses the effective use of an anti-gremlin-1 antibody to accelerate the healing and bridging of bone tissue in segmental gap defects; and demonstrates that inhibitors of gremlin-1 activity may provide improved therapies for treating or preventing fracture non-union.
US12240895B2	Heterotopic ossification and method of treatment The present inventors have uncovered the nature of heterotopic ossification HO progression as an excessive activation of TGF-β in recruitment of MSCs for osteogenesis in coupling with type H vessel formation. Systemic injection of TGF-β neutralizing antibody using the methods of the present invention, effectively attenuated HO progression in multiple different HO animal models. The present invention provides methods for prophylaxis and treatment of HO and also rare genetic diseases such as fibrodysplasia ossificans progressive (FOP) (also known as myositis ossificans progressive) and progressive osseous heteroplasia (POH). by inhibition of TGF-β.
US12240892B2	Pharmaceutical composition comprising expression or activity inhibitor of c-src for preventing or treating synucleinopathy A composition including a substance that inhibits an expression or activity of c-src and its use in inhibiting aggregation and/or migration of α-syn are disclosed. The composition may be a pharmaceutical composition and can be used for preventing or treating synucleinopathy. The substance can inhibit the signal transduction induced by α-syn migrating to adjacent cells, thus mitigating the cytotoxic influence of α-syn on the adjacent cells; and can inhibit the denaturation of monomeric α-syn into aggregated α-syn, which may be a major cause of synucleinopathy, and thus, can be beneficially used as a therapeutic agent for synucleinopathy.
US12240890B2	Compositions and methods for treating and/or preventing pathogenic fungal infection and for maintenance of microbiome commensalism Provided herein are compositions and methods for treating and/or preventing pathogenic fungal infection and for maintenance of microbiome commensalism. In particular, provided herein are compositions comprising modified peptide YY (PYY) peptides and therapeutic and/or prophylactic methods of use thereof.
US12240889B2	Decoy cytokine receptor An IL-11 binding receptor capable of binding to IL-11 and inhibiting IL-11 mediated signalling is disclosed. Also disclosed are compositions comprising the IL-11 binding receptor and methods using the IL-11 binding receptor.
US12240886B2	Peptide-HLA complexes and methods of producing same There is provided herein, the use of mammalian derived HLA class I molecule for in vitro peptide exchange. For example, there is provided a method of producing an HLA class I molecule complexed to a pre-selected peptide comprising: (a) providing a mammalian derived HLA class I molecule complexed to an existing peptide; (b) incubating, in vitro, the HLA class I molecule complexed to the existing peptide with the pre-selected peptide, wherein the pre-selected peptide is at a concentration sufficient to replace the existing peptide to produce the HLA class I molecule complexed to the pre-selected peptide; and the HLA class I molecule comprises α1, α2, α3 and β2m domains.
US12240884B2	Methods for improving the efficacy and expansion of immune cells The invention provides methods of making immune effector cells (e.g., T cells, NK cells) that can be engineered to express a chimeric antigen receptor (CAR), compositions and reaction mixtures comprising the same, and methods of treatment using the same.
US12240882B2	Fusion proteins comprising an engineered knottin peptide and uses thereof The present disclosure presents a general approach to engineering existing protein-protein interactions through domain addition and evolution. The disclosure teaches the creation of novel fusion proteins that include knottin peptides where a portion of the knottin peptide is replaced with a sequence that has been created for binding to a particular target. Such fusion proteins can also be bispecific or multi specific in that they can bind to and/or inhibit two or more receptors or receptor ligands. Knottins may be fused with an existing ligand (or receptor) as a general platform tor increasing the affinity of a ligand-receptor interaction or for creating a multi specific protein. In addition, the fusion proteins may comprise a knottin peptide fused to another protein where the other protein facilitates proper expression and folding of the knottin.
US12240881B2	Ultra-long acting insulin-Fc fusion protein and methods of use The present disclosure relates to compositions of insulin-Fc fusion proteins and their use to treat feline diabetes.
US12240873B2	Respiratory syncytial virus (RSV) vaccine The present invention relates to an mRNA sequence, comprising a coding region, encoding at least one antigenic peptide or protein of RSV infections Respiratory syncytial virus (RSV) or a fragment, variant or derivative thereof. Additionally the present invention relates to a composition comprising a plurality of mRNA sequences comprising a coding region, encoding at least one antigenic peptide or protein of RSV infections Respiratory syncytial virus (RSV) or a fragment, variant or derivative thereof. Furthermore it also discloses the use of the mRNA sequence or the composition comprising a plurality of mRNA sequences for the preparation of a pharmaceutical composition, especially a vaccine, e.g. for use in the prophylaxis or treatment of RSV infections Respiratory syncytial virus (RSV) infections. The present invention further describes a method of treatment or prophylaxis of RSV infections using the mRNA sequence.
US12240871B2	Method for producing peptide compound The present invention is to provide a method for producing a peptide containing an N-alkylamino acid, which comprises the following Steps (1) to (3). Step (1): a step of mixing an N-terminal protected amino acid or an N-terminal protected peptide with a carboxylic acid halide or a halogenated alkyl formate; Step (2): a step of mixing an amino acid or a peptide in which the N-terminal and the C-terminal are not protected with a trialkylsilylating agent; and Step (3): a step of mixing the product obtained in Step (1) with the product obtained in Step (2).
US12240865B2	Organic electroluminescent materials and devices A compound comprising a first bidentate ligand LA, wherein LA comprises a structure of Formula I; wherein Z is selected from the group consisting of O, S, NR, BR, CRKRL, C═CRKRL, SiRKRL, —CRKRLCRMRN—, —SiRKRLSiRMRN—, —CRKRLO—, —SiRKRLO—, and —CRK═CRL—; wherein ring A, ring B, and ring C are each independently a 5-membered carbocyclic ring, 5-membered heterocyclic ring, 6-membered carbocyclic ring or 6-membered heterocyclic ring; wherein LA is coordinated to a metal M forming a 5-membered chelate ring; wherein M is selected from the group consisting of Ir, Pt, Pd, Ru, Rh, Os, Re, Cu, Ag, and Au; wherein RA, RB, and RC each represent mono to the maximum allowable substitution, or no substitution; wherein each R, RK, RL, RM, RN, RA, RB, and RC is independently a hydrogen or a substituent selected from the group consisting of deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, germyl, boryl, selenyl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carboxylic acid, ether, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, and combinations thereof; wherein M is optionally coordinated to one or more other ligands; wherein any two substituents are optionally joined or fused together to form a ring; and with the provision that LA does not comprise the following structure:
US12240863B2	Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device An organometallic compound represented by Formula 1: M(L1)n1(L2)n2 Formula 1 In Formula 1, M is a transition metal; L1 is a ligand represented by Formula 2 as disclosed herein; L2 is a monodentate ligand, a bidentate ligand, a tridentate ligand, or a tetradentate ligand; n1 is 1, 2, or 3, wherein, when n1 is 2 or greater, two or more ligands L1 are identical to or different from each other; n2 is 0, 1, 2, 3, or 4, wherein, when n2 is 2 or greater, two or more ligands L2 are identical to or different from each other; and L1 and L2 are different from each other.
US12240861B2	Imidazo nitrogen heterocyclic compound and application thereof The present invention relates to an imidazoazacyclo compound and an application thereof. The compound of the present invention has a structure as shown in a formula I. The imidazoazacyclo compound of the present invention has the advantages of low sublimation temperature, good light stability, electrical stability and thermal stability, high refractive index, small difference of refractive index in a visible light area and the like, and an apparatus prepared by the compound has the advantages of low voltage, long service life, high luminous efficiency and the like and can be used in an organic luminescent apparatus. In particular, as an electron transmission material, a hole barrier layer material and a light extraction layer material, the imidazoazacyclo compound has the probability of being applied to an AMOLED industry.
US12240859B2	Turbinmicin compounds, compositions and uses thereof Turbinmicin, an isolated compound of Formula (I) or IA is provided. Turbinomycin compounds of Formula (II) or (IIA) are also provided. A compound isolated from a bacterial species from the sea squirt, Ecteinascidia turbinate, and having a chemical formula of C34H29NO11 is also provided. Compositions including turbinmicin and turbinmicin compounds, such as pharmaceutical compositions including effective amounts of turbinmicin or turbinomicing compounds for treating fungal infections such as Candida and Aspergillus, including drug-resistant strains thereof, are also disclosed. Methods of treating fungal infections with turbinmicin, turbinmicin compounds and compositions thereof are disclosed.
US12240855B2	Pyrrolopyrazole derivative The present invention provides a low molecular compound that inhibits phosphatidylserine synthase 1 or a pharmaceutically acceptable salt thereof, a pharmaceutical containing thereof, and a therapeutic agent for cancer having a suppressed function of phosphatidylserine synthase 2. The compound represented by formula (1) or a pharmaceutically acceptable salt thereof, wherein R1, ring Q1, ring Q2, and W are as defined in the specification.
US12240853B2	Compounds useful in HIV therapy The invention relates to a compound of the formula: salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
US12240849B2	Nitrogen-containing spiro derivative as RET inhibitor Disclosed are a series of compounds with a nitrogen-containing spiro structure and an application thereof in the preparation of an RET kinase inhibitor. Specifically, disclosed is a compound as shown in formula (II) or a pharmaceutically acceptable salt thereof.
US12240848B2	Azaindole rock inhibitors This invention provides rho-associated protein kinase (ROCK) inhibiting compounds for therapeutic applications as described further herein.
US12240846B2	5- and 6-azaindole compounds for inhibition of Bcr-Abl tyrosine kinases The present disclosure relates to compounds and compositions for inhibition of Bcr-Abl tyrosine kinases, methods of preparing said compounds and compositions, and their use in the treatment of various cancers, such as chronic myeloid leukemia (CML).
US12240844B2	Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease [Summary]The present invention relates to a pyrrolopyridine derivative and a pharmaceutical composition comprising the same as an active ingredient for prevention or treatment of a protein kinase-related disease. The pyrrolopyridine derivative has excellent inhibitory activity against various protein kinases including LRRK2, DYRK1, and CLK1 and exhibits an excellent suppressive effect on the growth of triple-negative breast cancer cells. A pharmaceutical composition comprising the same as an active ingredient can be advantageously used for treating or preventing protein kinase-related diseases, inter alia, cancers, degenerative brain diseases, and inflammatory diseases, and specifically for treating triple-negative breast cancer.
US12240840B2	Amide-substituted heterocyclic compounds for the treatment of conditions related to the modulation of IL-12, IL-23 and/or IFN-alpha Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.
US12240839B2	Cyclobutyl dihydroquinoline sulfonamide compounds The present invention provides a cyclobutyl dihydroquinoline sulfonamide compound of Formula (I), an enantiomer, diastereoisomer, atropisomer thereof, a mixture thereof, or a pharmaceutically acceptable salt thereof, that inhibits voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases associated with the activity of sodium channels such as pain disorders, cough, and itch. Also provided are pharmaceutical compositions containing the compounds of the present invention. Also further provided is an atropi-selective preparation of said compounds of Formula (I), and intermediate thereof.
US12240831B2	Pyridazinone compounds and uses thereof Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.
US12240830B2	Fused ring heteroaryl compounds and use thereof The invention provides novel substituted heterocyclic compounds represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of ALK5 and are useful in the treatment of chronic fibrosis, vascular disorder, obesity, diabetes, autoimmune diseases and cancer.
US12240829B2	Prostaglandin receptor EP2 antagonists, derivatives, and uses related thereto The disclosure relates to Prostnglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, epilepsy, neuroinflammation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof.
US12240815B2	Potent and selective human neuronal nitric oxide synthase inhibitors Disclosed are 2-aminopyridine derivative compounds for use as inhibitors of nitric oxide synthase (NOS). In particular, the field of the invention relates to 2-aminopyridine derivative compounds for use as inhibitors of neuronal nitric oxide synthase (nNOS), which are formulated as pharmaceutical compositions for treating diseases and disorders associated with nNOS such as Alzheimer's, Parkinson's, and Huntington's diseases, and amyotrophic lateral sclerosis, cerebral palsy, stroke/ischemic brain damage, and migraine headaches.
US12240812B2	Compound for inhibiting PGE2/EP4 signaling transduction inhibiting, preparation method therefor, and medical uses thereof A compound of formula (I), a preparation method therefor, a pharmaceutical composition containing a derivative thereof, and the therapeutic uses thereof, especially inhibiting PGE2/EP4 signalling transduction and the uses thereof for treating cancer, acute or chronic pain, migraine, osteoarthritis, rheumatoid arthritis, gout, bursitis, ankylosing spondylitis, primary dysmenorrhea, tumour or arteriosclerosis.
US12240810B2	Chiral-substituted poly-N-vinylpyrrolidinones and complexes with bimetallic nanoclusters and uses thereof in asymmetric oxidation reactions Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a bimetallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The catalytic complexes have exhibited the ability to achieve reaction products have a very high degree of optical purifies. These reaction products can be used as reagents in the synthesis of complex organic molecules, such as bioactive products, and C—H bond oxidation of complex molecules including various drugs and natural products.
US12240808B2	Process for the synthesis of calebin-a and its intermediates The invention discloses novel intermediates in the synthesis of Calebin A represented by formula 3. The invention also covers processes for the synthesis of Calebin-A and its analogs using compounds of formula 3.
US12240804B2	Onium salt, chemically amplified resist composition and patterning process An onium salt having formula (1) serving as an acid diffusion inhibitor and a chemically amplified resist composition comprising the acid diffusion inhibitor are provided. When processed by lithography, the resist composition forms a pattern having minimal defects and excellent lithography performance factors such as CDU, LWR and DOF.
US12240802B2	Production of petrochemical feedstocks and products using a fuel cell A method of producing petrochemicals using a hydrocarbon fuel cell includes the steps of operating the fuel cell to produce electricity, thermal energy, and one or more exhaust stream, the one or more exhaust stream comprising at least a carbon-containing gas and water, reacting at least a portion of the exhaust stream with the reactant stream of natural gas to produce one or more petrochemical streams in a reactor, and heating one or more reactants using at least a portion of at least one of the electricity and the thermal energy.
US12240794B2	Composition for producing N-vinyl carboxylic acid amide A composition for producing an N-vinylcarboxylic acid amide includes (A) an N-(1-alkoxyethyl)carboxylic acid amide and (B) a carboxylic acid amide other than the N-(1-alkoxyethyl)carboxylic acid amide and the N-vinylcarboxylic acid amide, and satisfies the following conditions: (1) the composition has a melting point of 0 to 30° C.; (2) a water content is 0 to 1.00% by mass in a total amount of the composition; (3) a content ratio of the component (A) to the component (B) is 4.0 to 20.0 in terms of a molar ratio; and (4) a 5% by mass aqueous solution of the composition has a pH of 4.0 to 8.0. A method for producing an N-vinylcarboxylic acid amide includes thermally decomposing or catalytically decomposing the composition for producing an N-vinylcarboxylic acid amide.
US12240791B1	Process for selective ethylene oligomerization with antifouling components A process for selectively producing oligomers may comprise bringing at least one antifouling agent into contact with a first amount of at least one aluminum alkyl compound to form at least one antifouling compound comprising the structure or its dimeric form; and feeding the at least one antifouling compound, an additional amount of the at least one aluminum alkyl compound, at least one titanate compound, and ethylene into a jet loop reactor and oligomerizing ethylene to produce one or more of 1-butene, 1-hexene, or 1-octene. One or more of the chemical groups R1, R2, and R3 may be the antifouling agent comprising the structure —O((CH2)nO)mR4. n may be an integer of from 1 to 20. m may be an integer of from 1 to 100. R4 may be a hydrocarbyl group. In embodiments, the chemical groups R1, R2, or R3 that do not comprise the antifouling agent, if any, may be hydrocarbyl groups. The at least one titanate compound may be fed as a stream separate from the streams of the at least one antifouling compound and the additional amount of the at least one aluminum alkyl compound. The of the sum of the first amount and the additional amount of the at least one aluminum alkyl compound to the at least one titanate compound may be equal to or higher than 1.5 and equal to or lower than 3.0.
US12240788B2	Silicon carbide body with localized diamond reinforcement A reaction-bonded silicon carbide (SiC) body is produced by: providing a preform including ceramic elements and carbon, and one or more surface features; providing a powder which includes diamond particles and carbon; locating the powder in the surface feature(s); and infiltrating the preform and the powder with molten silicon (Si) to form reaction-bonded SiC in the preform, and to form reaction-bonded SiC coatings on the diamond particles. The present disclosure also relates to a device/component which includes: a main body portion and discrete elements located at least partially within the main body portion. The main body portion may include reaction-bonded SiC and Si, but not diamond, while the discrete elements include diamond particles, reaction-bonded SiC coatings surrounding the diamond particles, and Si. According to the present disclosure, diamond may be advantageously located only where it is needed.
US12240786B2	Inorganic material with improved properties Suggested is a solid formed with Si, Al, Ca, O and at least one of Na and K, characterized in that in the 27Al-MAS-NMR spectra of the solid compared to the 27Al-MAS-NMR spectrum of calcium aluminate, an additional signal is present which has a chemical shift which lies between that of the main peak of calcium aluminate and that peak of calcium aluminate which is closest to the main peak in the higher field. 2.
US12240784B2	Cementitious hybrid flooring composition A multi-component composition comprising a first component including water, and a second component including at least one hydraulic binder, wherein the multi-component composition includes a copolymer CP, wherein the copolymer is a vinyl versatate copolymer CPA, and/or a copolymer based on styrene and (meth) acrylic acid esters CPB. The amount of hydraulic binder, based on the total weight of the multi-component composition, is from 25-65 weight-%. The multi-component composition is especially suitable as a flooring material for industrial floors and car parks.
US12240783B2	Class C fly ash-based cementitious materials, flowable fill, concrete, and related techniques Class C fly ash-based cementitious materials, concretes, and related techniques are disclosed. In accordance with some embodiments, an activated class C fly ash-based cementitious material may be produced by intergrinding class C fly ash (e.g., classified to remove quartz and/or other contaminants and, thus, increase the reactive materials present), an activator, sodium citrate, borax, and a polycarboxylate material. The class C fly ash may have an amorphous glass content of about 60 wt % or more, a calcium oxide (CaO2) content of about 20 wt % or more, and a quartz content of about 10 wt % or less. The activator may be a chemical which reacts with class C fly ash to form strätlingite structures therein when introduced with water. In some cases, the cementitious material may be provided as an all-in-one powder blend. In some cases, techniques disclosed herein may be utilized in providing a fast-setting flowable fill material.
US12240779B2	Crystallized glass of three-dimensional shape, chemically strengthened glass of three-dimensional shape, and method for producing crystallized glass of three-dimensional shape and chemically strengthened glass of three-dimensional shape The present invention provides crystallized glass of three-dimensional shape for easily producing chemically strengthened glass of three-dimensional shape that resists damage and has exceptional transparency. This crystallized glass of three-dimensional shape: contains crystals; has light transmittance in terms of a thickness of 0.8 mm of 80% or higher; and contains 45-74% SiO2, 1-30% Al2O3, 1-25% Li2O, 0-10% Na2O, 0-5% K2O, a total of 0-15% of SnO2 and/or ZrO2, and 0-12% P2O5, these amounts expressing the oxide-based mass percentage.
US12240777B2	Glass tube At least one glass tube has an azimuthal wall thickness deviation WTD of not more than 6.0%, the azimuthal wall thickness deviation being determined based on a lowest wall thickness value and a highest wall thickness value measured within a cross-section of the at least one glass tube, the azimuthal wall thickness deviation WTD being calculated according to the following formula: W ⁢ ⁢ T ⁢ ⁢ D = 100 - ( lowest ⁢ ⁢ wall ⁢ ⁢ thickness ⁢ ⁢ value highest ⁢ ⁢ wall ⁢ ⁢ thickness ⁢ ⁢ value * 100 ) ⁢ ⁢ % .
US12240773B2	Mixing systems and methods of mixing A system for mixing and mixing processes and structures are disclosed. In addition a nozzle used for mixing is disclosed.
US12240772B2	Treatment of aqueous composition with metal component A method of treating feed water includes adding a metal component to the feed water to form a clarified aqueous composition.
US12240766B2	Defect-free lithium nickel(3+) oxide materials for use in lithium batteries and method of preparation thereof Substantially defect-free layered lithium nickel oxide materials of Formula (I): Li(1−x)(Ni(1−y)My)(1+x)O2 and Formula (II): LiaNibMc O2 are provided herein, wherein M is one or more metal selected from the group consisting of Co, Mn, Al, Mg, Ti, B, Zr, Nb, and Mo; 0≤x≤0.05; and 0≤y≤0.1, 0.97≤a≤1.03; 0.9≤b≤1; 0≤c≤0.1; and 0.97≤(b+c)≤1.03; and the material has a layered structure with no more than about 1.2 percent disorder between lithium and transition metal (TM) layers, as determined by structural refinement calculations on x-ray diffraction (XRD) data, compared to an ideal layered LiNiO2 structure. The materials can be formed by heating Ni(OH)2 or NiO with lithium hydroxide at a temperature in the range of about 650 to 680° C.
US12240765B1	Borate method for magnetite synthesis The present disclosure is drawn to a method for producing magnetite comprising the steps of: forming a ferrous ion solution; forming a ferric ion solution; and mixing and heating the ferrous ion solution and the ferric ion solution with a boric ion solution to precipitate magnetite. The disclosure is drawn to a borate method for producing magnetite wherein a ferrous ion compound and a ferric ion compound, in stoichiometric ratio of 1:2, are precipitated with a boric ion compound.
US12240757B2	Syngas production via supercritical water A method to produce syngas from a feed oil comprising the steps of increasing a pressure of a slurry catalyst; increasing a temperature of the pressurized slurry stream; increasing a pressure of the feed oil; increasing a temperature of the pressurized feed stream; mixing the hot slurry stream and the hot oil stream; increasing a temperature of the mixed stream in a combined heater to produce a hot mixed stream; maintaining upgrading reactions of hydrocarbons in the supercritical reactor to produce a supercritical effluent; reducing a pressure of the supercritical effluent; separating the depressurized effluent in a separator to produce a gas stream; separating the gas stream to produce a light hydrocarbon stream; mixing the light hydrocarbon stream and a catalyst feed; introducing the hot feed to a steam reformer; maintaining water gas shift reactions of the light hydrocarbon gases in the steam reformer to produce a reformer effluent.
US12240755B2	Method for producing compressed hydrogen using electrochemical systems According to embodiments of the present disclosure, a method of producing hydrogen in a fuel cell includes passing ammonia under pressure to an anode of the fuel cell, where the ammonia is decomposed into nitrogen gas and protons. The fuel cell comprises a cathode, the anode, and a proton-conducting electrolyte between the anode and the cathode. The anode includes an ammonia decomposition catalyst. The method further includes passing the purging the nitrogen from the anode, passing the protons through the proton-conducting electrolyte to the cathode, and passing the electrons from the anode to the cathode, wherein the protons and the electrons react to produce substantially pure hydrogen gas under pressure.
US12240751B2	Sensor package substrate, sensor module having the same, and sensor package substrate manufacturing method A sensor package substrate has through holes V1 and V2 at a position overlapping a sensor chip mounting area. The through hole V1 has a minimum inner diameter at a depth position D1, and the through hole V2 has a minimum inner diameter at a depth position D2 different from the depth position D1. Thus, since the plurality of through holes are formed at a position overlapping the sensor chip mounting area, the diameter of each of the through holes can be reduced. This makes foreign matters unlikely to enter through the through holes, and a reduction in the strength of the substrate is suppressed. In addition, since the depth position D1 and depth position D2 are located at different depth levels, it is possible to sufficiently maintain the strength of a part of the substrate that is positioned between the through holes V1 and V2.
US12240749B2	MEMS device, assembly comprising the MEMS device, and methods for operating the MEMS device Proposed is a MEMS device comprising a layer stack having at least one second layer formed between a first layer and a third layer. At least one first cavity is formed in the second layer. The MEMS device further comprises a laterally deflectable member having an end connected to a sidewall of the first cavity and a free end. Further, the MEMS device includes a passive element rigidly tethered to the free end of the laterally deflectable element to follow movement of the laterally deflectable element. The laterally deflectable element and the passive element divide the first cavity into a first sub-cavity and a second sub-cavity. The first sub-cavity is in contact with an ambient fluid of the MEMS device via at least a first opening. Further, the second subcavity is in contact with the ambient fluid of the MEMS device via at least a second opening. The at least one first opening is formed in a different layer of the first layer and the third layer than the at least one second opening.
US12240748B2	MEMS die and MEMS-based sensor A micro-electro-mechanical systems (MEMS) die includes a piston; an electrode facing the piston, wherein a capacitance between the piston and the electrode changes as the distance between the piston and the electrode changes; and a resilient structure (e.g., a gasket or a pleated wall) disposed between the piston and the electrode, wherein the resilient structure supports the piston and resists the movement of the piston with respect to the electrode. A back volume is bounded by the piston and the resilient structure and the resilient structure blocks air from leaving the back volume. The piston may be a rigid body made of a conductive material, such as metal or a doped semiconductor. The MEMS die may also include a second resilient structure, which provides further support to the piston and is disposed within the back volume.
US12240745B2	Contactless beverage dispensing methods A method of selecting and dispensing a custom beverage in a contactless manner using a mobile electronic device. The method includes launching a microsite on the mobile electronic device. The method further includes receiving a beverage selection via the microsite on the mobile electronic device, and receiving a selection of a volume of the custom beverage to be dispensed via the microsite. The method further includes generating a QR code via the microsite, wherein the QR code corresponds to the beverage selection and the volume selection and displaying the QR code on a display of the mobile electronic device such that when the QR code is read by a reader of a beverage dispenser, the selected beverage is dispensed in the selected volume based on the QR code.
US12240744B2	Lifter device A lifter device includes: a pole; a lifting member configured to be guided by the pole; a motor configured to generate power used for ascending and descending of the lifting member; a transmission mechanism configured to transmit the power of the motor to the lifting member; and a preventing member configured to prevent the descending of the lifting member when the power is not transmitted.
US12240743B2	Cargo loader The present disclosure provides a cargo loader comprising a tractor assembly and a vertical adjustment assembly carried by the tractor assembly. The vertical adjustment assembly comprises a base, a deck platform linked to the base by a lifting mechanism. The lifting mechanism is configured to retract and extend in a vertical direction such that a height of the deck platform varies between a retracted height and an extended height. The vertical assembly further comprises an attachment. The attachment is interchangeably and removably coupled to the deck platform and configured to vary between the predetermined retracted height and the predetermined extended height.
US12240740B2	Method and apparatus for operating a slew bearing A slew bearing that includes an inner ring. The slew bearing also includes a first outer ring positioned about a first portion of the inner ring. The slew bearing also includes a second outer ring operably engaged with the first outer ring, wherein the second outer ring is positioned about a second portion of the inner ring opposite to the first outer ring. The slew bearing also includes at least one set of ball operably engaged with the inner ring and one or both of the first outer ring and the second outer ring. The inner ring of the slew bearing is configured to rotate about the first outer ring and the second outer ring.
US12240739B2	System and method for increasing the load carrying capacity of a telescopic crane boom A telescopic boom that includes a plurality of extensible boom sections and a power source for delivering translational force to the boom sections. The boom further includes at least one rope transiting between boom sections wherein a first section is extending, and the second section is adjacent to the extending sections. The rope is redirected by at least one sheave mounted to the adjacent section and further redirected by at least one sheave mounted to the extensible section.
US12240738B2	Telescopic jib with swing-out mast A telescopic jib includes a main box, at least one inner box and at least one swing-out mast. The mast is arranged on the inner box such that the inner box is able to be pushed into the main box together with the mast in a swung-in or folded-in position to thereby provide a telescopic jib that more easily provides an increased load-bearing capacity. In a particular configuration such a telescopic jib is disposed on a vehicle crane having wheels, axles, a lower carriage and a superstructure, with the telescopic jib mounted to the superstructure.
US12240737B2	Work machine swiveling frame and assembly method for work machine swiveling frame A slewing frame of a work machine and a method of assembling a slewing frame of a work machine where the slewing frame is separable into at least two front and rear members, and an operation of connecting these two members can be easily performed. A slewing frame is separable into a front frame and a rear frame. When a pin fitting portion of a rear frame is fitted on a positioning pin of a front frame, and the rear frame is rotated downward, at a position where a front pin hole and a rear pin hole are aligned with each other, a contact portion of the rear connecting portion is brought into contact with a rotation preventing portion. As a result, a connecting pin can be easily inserted into the front pin hole and the rear pin hole.
US12240734B2	Elevator guide rail A guide rail for an elevator system has an elongate length with a cross-section perpendicular to the length; the cross-section including a base section for mounting to a wall of a hoistway, and a blade section extending from the base section; the blade section including a guide surface for interacting with a guide element of a component movable in the elevator hoistway; the guide rail including: a pair of separate rail piece parts fixed together to form the guide rail; the pair of separate rail piece parts including a first rail piece part and a second rail piece part; the first rail piece part being formed from a first thickness of sheet material bent to have a cross-section of a first predetermined shape, and the second rail piece part being formed from a second thickness of sheet material bent to have a cross-section of a second predetermined shape.
US12240732B2	Notification system and method for an elevator and an elevator system A notification system and a notification method for an elevator, and an elevator system are provided by the present disclosure. The notification system for an elevator includes: a wake-up module, which is configured to wake up a user mobile terminal when the user mobile terminal enters a specified area, so that the user mobile terminal sends a request to a server; and the server, which is configured to receive a reminder item setting from an administrator, and which is configured to push a reminder item to the user mobile terminal upon receiving the request from the user mobile terminal, the reminder item including elevator repair or maintenance information. The system and method according to the present disclosure allows a user to conveniently know about elevator repair or maintenance information.
US12240731B2	Sheet separation device, laminator, image forming apparatus, and image forming system A sheet separation device that conveys a two-ply sheet in a state where the one side joined is located on an upstream side or a downstream side of the two-ply sheet in a conveyance direction, separates the two-ply sheet into the two sheets, and inserts an inner sheet from a non-joined side opposite the joined side in the sheet conveyance direction so that the inner sheet is sandwiched between the two sheets overlaid with each other includes a conveying roller pair including a pair of rollers and circuitry. The conveying roller pair conveys the two-ply sheet and holds a joined portion of in the two-ply sheet at which the two sheets are joined, at a nip portion of the conveying roller pair when the inner sheet is inserted into the two-ply sheet. The circuitry contacts the inner sheet against the joined portion of the two-ply sheet to perform skew correction.
US12240728B2	Winding module and winding installation for metal wires A winding module and a winding installation including winding modules for winding metal wire. In such a winding installation or take-up bench a driven capstan is used to pull the metal wire through a processing installation before being led onto a take-up spool. The spool is driven by a cantilever supported shaft. In prior art take-up benches, both the capstan and the spool is reachable by an operator from the same side. This means that the capstan direction—the direction from the driven side of the capstan to the operator side—is equal to the shaft direction—the direction from the drive side of the shaft to the open end of the shaft. In the inventive winding module the capstan direction is opposite to the shaft direction, which provides a completely different operation of the winding module and the winding installation and facilitates the introduction of doffing robots.
US12240722B2	Feeding device and image forming apparatus A feeding device includes: a supply unit that supplies air into space between plural media loaded to float the media; a feeder that adsorbs the media floated by the supply unit and feeds the media; a separator that supplies air to a second medium disposed immediately below a first medium adsorbed by the feeder to separate the second medium from the first medium; a detector that detects a position of at least one of the first medium and the second medium after air is supplied by the separator; and a modifier that modifies a condition related to a feeding operation of the feeder based a position detected by the detector.
US12240720B2	Separation device for removing a profiled element from a conveying surface, and extrusion machine provided with such a separation device A separation device (1) intended to separate a profiled element (2) from a conveying surface (3) which conveys the profiled element (2) in a longitudinal direction (L0) comprises a detachment roller (10) which is mounted so as to be able to rotate on a support (11) about a detachment axis (X10), and which is intended to be interposed, in an engagement configuration (C1), between the profiled element (2) and the conveying surface (3) to cause the profiled element (2) to become detached from the conveying surface (3).
US12240718B2	Method and apparatus for separating and spooling a paper web A paper tape turn-up construct including a cover flap and a multi-bend structure to both protect an adhesive layer and to build an optimized elevated structure to present the adhesive layer during initiation of the paper web turn up process. Methods and apparatus to form the constructs and apply the constructs to paper production equipment are also included. The multi-bend paper turn up construct includes layers of adhesive and pulpable substrate with strategically located release materials, such as silicon that enhance a bridging of a gap between a rotating paper web and an empty spool surface.
US12240714B2	Robotic system to load and unload trucks and other containers A robotic system is disclosed which includes a robotic arm having n degrees of freedom, the robotic arm comprising a base and a set of serially connected links and joints connected to the base; an enabler joint assembly comprising a mounting location at which the base of the robotic arm is mounted and having a rotational axis, offset from the mounting location, about which the enabler joint assembly is configured to rotate the mounting location; and a processor configured to control a first set of motors associated with the n degrees of freedom of the robotic arm and an enabler joint motor comprising the enabler joint assembly to control operation of the robotic arm within an extended operating space defined at least in part by the n degrees of freedom of the robotic arm and an (n+1)th degree of freedom provided by the enabler joint assembly.
US12240710B2	Apparatus and method for handling portable traffic delineators An apparatus and method for handling portable traffic delineators includes a lifting arm assembly and a gripper assembly arranged to move portable traffic delineators between a cargo platform on a vehicle and a road surface. The gripper assembly has guide rails that define a V-shaped receiving structure with rollers to guide and center the portable traffic delineators within the V-shaped receiving structure. The gripper assembly also has suction cups arranged to pivot into and out of the V-shaped receiving structure for applying a suction force to the outer surface of the portable traffic delineators received in the V-shaped receiving structure. A programmable controller is used to perform a sequence of movements of the lifting arm assembly and the gripper assembly to either retrieve portable traffic delineators from a roadway or place portable traffic delineators on the roadway when the portable traffic delineators are detected within the V-shaped receiving structure.
US12240705B2	Lift gate apparatus A lift gate apparatus includes a movable conveyor device and a bracket. The movable conveyor device is configured to transition between a conveying position and a non-conveying position. The bracket configured to bridge a gap between the movable conveyor device and a fixed conveyor device, wherein the bracket pivots and slides over the fixed conveyor device when the movable conveyor device is transitioned from the conveying position to the non-conveying position.
US12240701B2	Apparatus for transporting container and system for storing container with the apparatus Provided are a container transporting apparatus for storing items such as FOUPs and reticle pods by utilizing the dead zone space located in an upper portion of the semiconductor manufacturing facility built in the FAB, and a container storage system having the same. The container storage system may include a first storage unit installed on a side of a movement path of a transporting device for transporting a container accommodating a substrate and for storing the container; a second storage unit installed on a side of the first storage unit and for storing the container; and a transporting unit moving between the first storage unit and the second storage unit and for transporting the container stored in the first storage unit to the second storage unit.
US12240696B2	Automated warehouse system, method for correcting misalignment of placement position of article in automated warehouse system, computer program, and recording medium A control unit provided in an automated warehouse system includes a misalignment determination unit that, after storage of an article in a storage rack, determines whether or not an article is estimated to have been subjected to vibration exceeding a predetermined threshold value, and a misalignment correction instruction unit that, if the misalignment determination unit determined that the article is estimated to have been subjected to vibration exceeding the predetermined threshold value, outputs a control signal to a transport device to drive the transport device to execute a misalignment correction operation with respect to the placement position of the article.
US12240693B1	Garbage bin cleaning system with gas motor A vehicle mounted garbage bin cleaning system includes a pair of arms configured for lifting a garbage bin, the arms rotatably coupled to a mount on a vehicle, a hopper configured for accepting the garbage bin when the arms lift the garbage bin into the hopper, spray rods extending upwards from the hopper and that spray water jets to clean an interior of the garbage bin, a gas-powered motor that uses a mechanical means to drive two pressure washer pumps, and wherein the spray rods are fluidically coupled with the two pressure washer pumps.
US12240690B2	Receptacle lid fastener According to the present disclosure, a lid fastener and receptacle assembly is provided to removably secure the lid of a garbage receptacle assembly. Lid fastener is designed to allow the contents of the receptacle assembly to be secured within the assembly while it is in an upright position and automatically disengage when receptacle assembly is in the dumping position, relocking when receptacle assembly is returned to the upright position.
US12240688B2	Conical wall riser with interleaved tab connectors A plastic article useful as a riser assembly for a septic tank or as part of another structure is comprised of a multiplicity of identical shape conical wall plastic risers. The risers are attached to each other at joints by tabs which engage rim segments; each end of the riser has alternating tabs and rim segments. A riser assembly wall undulates in the lengthwise direction. The risers nest within each other for shipment or storage.
US12240686B2	Cassette for accommodating glass, method for loading glass into cassette, and method for manufacturing cover window A cassette for accommodating glass includes: a cassette main body for accommodating a plurality of glasses; a housing arranged on at least one side of the cassette main body and including a plurality of openings arranged side by side in one direction; and a plurality of doors configured to open and close the plurality of openings.
US12240682B2	Biotic material apparatus for thermally protecting and/or transporting temperature sensitive products Embodiments of the subject invention relate to a method and apparatus for shipping products so as to control the temperatures the products are exposed to. Embodiments can increase the amount of time the product and/or portions of the product experience a desired temperature range and/or reduce the amount of time the product and/or portions of the product experience temperatures outside of the desired temperature range and/or experience an undesirable temperature range. Embodiments can incorporate biotic materials, such as wood fibers or moss, positioned around and/or near the product positioned inside a packaging container or around a pallet load, such that the biotic materials restrict heat flow from one or more locations on the exterior of the package to one or more other locations in the interior of the package.
US12240678B2	Bag-like container A bag-like container includes a bottom sheet including a first paper base layer and a heating element layer configured to generate heat by absorbing electromagnetic waves; and a top sheet bonded to the bottom sheet in such a manner as to be separable from the bottom sheet with a content to be cooked being contained, wherein the top sheet transmits the electromagnetic waves.
US12240676B2	Packing material A packing material includes: a packing case; a support member arranged inside the packing case and having a first side plate facing one side face of a packed article in a first direction; a cushioning member disposed between the packing case and the first side plate and absorbing shock applied from the first direction to the packed article; and a shock distribution plate disposed between the first side plate and the cushioning member, larger than the contact area with the cushioning member and elongate in a second direction intersecting with the first direction. The shock distribution plate has such rigidity as not to deform against shock from the cushioning member.
US12240673B2	Packaging unit from a moulded pulp material with peelable laminated layer and method for manufacturing such packaging unit The present invention relates to a packaging unit (2) for a moulded pulp material and a manufacturing process therefore. The packaging unit according to the invention comprises a product receiving or carrying compartment having a product contact surface, wherein the product contact surface comprises a peelable laminate layer (10). In a presently preferred embodiment the moulded pulp material comprises an amount of a bio-degradable aliphatic polyester.
US12240672B2	Packaging material A packaging material comprising a substrate and a liner extending along the substrate. The liner comprises at least a biopolymer and graphene nanoplatelets to provide a gas barrier along at least a portion of the packaging material.
US12240671B2	Packing material and packed product Provided is a packing material for packing a packing object, and includes: a sheet having an opening area that is surrounded by a cut line; and a label fixed to the opening area. The opening area is configured to be separable from the sheet by breaking the cut line by pulling the label in a direction in which the label is separated from the sheet.
US12240669B2	Receptacle for holding an active substance and corresponding closure and container with such a receptacle A receptacle forming a chamber partially filled with an active substance, wherein the receptacle is a body and a cap which closes the body. The cap includes a top wall with a first main side facing an interior of the chamber and a skirt formed with the first main side of the top wall. The body includes a bottom wall and a sidewall. The skirt and the sidewall surround one another in contact with each other. The walls surrounding the chamber include the bottom wall, the top wall and either the skirt or the sidewall. At least one ventilation path is provided between the skirt and the sidewall, such that the ventilation path connects the chamber with the outside atmosphere.
US12240666B2	Cuboid folding box A one-piece blank for a cuboid folding box includes five main panel segments arranged in a row and separated from one another on transverse sides via main fold lines, a second secondary panel segment adjoining a second main panel segment on a longitudinal side, including an edge, and adjoining the second main panel segment via a second secondary fold line, and a third secondary panel segment adjoining a third main panel segment on a longitudinal side via a third secondary fold line. The secondary fold lines are perpendicular to the main fold lines, a first perforation line extends over the third main panel segment and at least partially over the third secondary panel segments. The third secondary panel segments are each divided by the first perforation line into a first region adjacent to the second secondary panel segment and a second region adjacent to the fourth secondary panel segment. Shapes of the second secondary panel segments and a course of the first perforation line are such that, in a folded state, the second secondary panel segments overhang the first perforation line in a region of the third secondary panel segments.
US12240664B2	Packaging for reel-less bundle of cable A packaging arrangement for a bundle of cable includes a planar packaging blank extending in a longitudinal direction from a first end to a second end. The blank includes a middle region extending from the first end to the second end between a first fold line and a second fold line, a first side extending from the first end to the second end and including a plurality of first flaps extending from the first fold line in a direction away from the second side in a direction perpendicular to the longitudinal direction, and a second side extending from the first end to the second end and including a plurality of second flaps extending from the second fold line in a direction away from the first side in a direction perpendicular to the longitudinal direction. The blank is configured to be rolled into a cylindrical shape such that the first end overlaps the second end. The plurality of first flaps are configured to be folded radially inward relative to the cylindrical blank, and the plurality of second flaps are configured to be folded radially inward relative to the cylindrical blank.
US12240660B2	Paper based container for household products A container including a paperboard shell layer and a paperboard core layer. The container has a predetermined removable portion the provides for a separable cap portion. The body portion of the container extends from the shell bottom edge to a lower line of limitation. The body portion includes a lobe beneath the lower line of limitation defining the body. The lobe can be used to tightly fit the cap portion to the body portion after opening the container.
US12240659B2	Metal screw cap, pop-top can and metal screw cap manufacturing method A metal screw cap (1), a pop-top can and a metal screw cap (1) manufacturing method. The metal screw cap (1) includes a screw cap body (10), where an inner wall of the screw cap body (10) encloses a channel for liquid to flow out; the screw cap body (10) includes a threaded portion (11), an arc-shaped portion (12) and an hemming portion (13); the arc-shaped portion (12) includes a plurality of circular arc-shaped segments connected end to end; the threaded portion (11) is used for threaded sealing connection with a lid, and the hemming portion (13) is used for seaming with a turned edge of a can body. The pop-top can includes the can body and the metal screw cap (1). The metal screw cap (1) manufacturing method is used for manufacturing the metal screw cap (1).
US12240655B2	Lid for dispensing measured powder amounts A dispensing lid assembly having a lid portion that seals off the opening of the container but for an aperture and a centrally disposed interface void. The lid portion provides an integrated, external measuring spout in communication with the aperture. A dial portion may be rotatably coupled to the lid portion so that they rotate independent of each other. The dial portion is operatively associated with a diaphragm disposed under the lid portion so that rotation of the dial portion selectively moves the diaphragm between an open configuration and a closed configuration closing off the aperture and fluidly disconnecting the compartment of the container from the external measuring spout.
US12240654B2	Liner for food receiver of food holding apparatus Food holding system, liner thereof, and associated methods. A food tray receiver liner is configured to be installed in a food tray receiver. The liner is configured to collect food that may fall into the food tray receiver. Desirably, the liner obstructs food from passing between the liner and side walls of the food tray receiver.
US12240652B2	Containers and systems for use during external sterilization of drug delivery devices A container and systems for use during an external sterilization process of a plurality of drug delivery devices are provided. The container may include an outer housing and at least one partition at least partially enclosed by the outer housing. The at least one partition may include a plurality of first dividers and a plurality of second dividers. The at least one partition may also be positioned an open configuration, wherein the plurality of first dividers and the plurality of second dividers cooperate with each other to define a plurality of chambers configured to receive at least one of the plurality of drug delivery devices. The at least one partition may also be positioned in a closed configuration wherein the plurality of chambers are substantially completely collapsed.
US12240647B2	Bag hanger for cleanroom environment A bag hanger has a main bracket body with a first leg configured for mounting the main bracket body on a support and a second leg extending from the first leg that is configured for hanging a bag. The second leg includes an open-ended slot that is accessible at a distal end of the second leg, the open-ended slot being sized to receive at least one hangable portion of the bag.
US12240645B2	Strap-feeding assembly with strap-size-adjustment features Various embodiments of the present disclosure provide a strapping machine strap-feeding assembly with features that enable adjustment of the strap-feeding assembly to accommodate different strap sizes.
US12240644B2	Bud sorting and packaging apparatus, systems and methods A cannabis bud sorting, picking and filling system includes a computer vision system operable to view and estimate the weight of a plurality of buds on a bud picking tray and to direct a bud picker robot to pick a plurality of buds from the bud picking tray and deposit the picked buds in an amount to load a container to its predetermined loaded target weight. A computer vision system acquires a digital image of product items having a product type, identifying each product item in the image, determining a pixel-based area for each identified product item, predicting a weight of each identified product item based on a size thereof, the determined pixel-based area and a predetermined density based on the product type, grouping, based on the predicted weights, the identified product items into groups satisfying the target weight, and automatedly picking and placing each group into a container.
US12240639B2	Mobile automated modular product packing system and method Product packing systems and methods are provided. A product packing system may include multiple product packing production sections and multiple modular frame sections. Each modular frame section may support one of the product packing production sections and be configured to connect to an adjacent modular frame section. An assembled product packing system may be transported to an installation location and moved to an installation site at the installation location.
US12240633B2	Rotary wing vehicle A rotary wing vehicle includes a body structure having an elongated tubular backbone or core, and a counter-rotating coaxial rotor system having rotors with each rotor having a separate motor to drive the rotors about a common rotor axis of rotation. The rotor system is used to move the rotary wing vehicle in directional flight.
US12240630B2	Spacecraft servicing devices and related assemblies, systems, and methods Spacecraft servicing systems include a spacecraft servicing device and at least one mission extension pod comprising at least one spacecraft servicing component. The spacecraft servicing device is configured to transfer the at least pod to a target spacecraft in order to service the target spacecraft with the at least one spacecraft servicing component of the at least one pod. Spacecraft servicing pods configured to be supplied to a spacecraft with a spacecraft servicing device include at least one spacecraft servicing component.
US12240628B2	System contextual information manager A status information management system correlates checklist data from all stored checklists to create a holistic, function level representation of aircraft health. Components are associated with defined function level categories. When a component fault is detected, the contextual information management system identifies each function level category that includes that component, and flags that function level category as having a fault. Such flags may be represented on a display where each function level category is displayed. A flight crew member selecting the function level category may see all systems impacted by the component fault. When selecting a function level category, the information management system may render a graphical depiction of the aircraft and the systems included in the function level category. The component fault may be depicted along with an impact criticality to the rendered systems.
US12240626B2	Detachable power cable for unmanned aerial vehicle A surveillance drone system is provided herein generally including an UAV, a base power station, and, a tether for connecting the UAV to the base power station to provide electrical power to the UAV when airborne. The base power station may include a cable take-up assembly for releasing and taking up the tether. A plug or power module is provided at the free end of the tether configured to be detachably coupled with the UAV, to transmit electrical power to, and, possibly, data to and from, the UAV. With the plug or power module being detached, the UAV is free to fly unrestricted. This arrangement allows for the UAV to be airborne for prolonged periods to allow for monitoring a region and for release to allow the UAV to investigate anomalies in the monitored region.
US12240624B1	Aircraft gas turbine engine with heated fuel to assist combustion An aircraft gas turbine includes a combustor that combusts compressed air and at least one fuel flow from at least one fuel source to generate combustion gases. A fuel supply system is arranged to provide at least one of a first flow of fuel to the combustor via a first fuel supply line and a second flow of a heated fuel to the combustor via a second fuel supply line. A fuel heat exchanger is arranged within the fuel supply system to generate the heated fuel that is heated above an autoignition temperature of the fuel, and a heat source communicates with the fuel heat exchanger for generating the heated fuel.
US12240622B2	Aircraft assembly An aircraft assembly is disclosed including an aircraft panel, a channel attached to the aircraft panel, a fuel line for carrying cryogenic fuel, the fuel line disposed in the channel, and a sealed containment space around the fuel line for containing cryogenic fuel leaked from the fuel line, the containment space defined between the channel, the fuel pipe, and the aircraft panel.
US12240620B2	Thermal management system A thermal management system enables fluid coupling of the cooling circuits for the battery and the propeller arrangements. More than one propeller arrangement can be serviced by the same cooling circuit, but distribution of the coolant may be finessed. Optional pathways are provided to use heated coolant for heating (e.g., de-icing, cabin heating, etc.) before cooling the coolant. Fluid coupling of conduits between and/or within the cooling circuits provide redundancy to accommodate various faults and equipment malfunctions.
US12240618B2	Turbojet engine fan casing A fan casing for an aircraft bypass turbojet engine includes one single wall configured to form at least one portion of an outer skin of a nacelle. The wall includes at least one reinforcement for stiffening the fan casing. The reinforcement is formed by a portion of the wall forming at least one annular area projecting towards an inside of the nacelle and/or having an overthickness. The reinforcement is further configured for fastening the fan casing to arms crossing a secondary stream flow path of the turbojet engine.
US12240617B2	Systems, methods, and mechanical designs for inverters for eVTOL aircraft An electrical propulsion system for a vertical take-off and landing (VTOL) aircraft comprises an electrical motor assembly and an inverter assembly. The inverter assembly comprises a housing, a capacitor assembly, at least one printed circuit board assembly (PCBA), and a plurality of positioning pins. The capacitor assembly comprises a center hole, at least one capacitor, a capacitor housing having at least one busbar, and a plurality of through holes in the capacitor housing. The capacitor assembly and the at least one PCBA are positioned inside the housing. The plurality of positioning pins pass through the through the plurality of through holes of the capacitor housing and the at least one PCBA and are connected to the housing.
US12240613B2	Gas turbine combustion section having an integrated fuel cell assembly A combustion section defines an axial direction, a radial direction, and a circumferential direction. The combustion section includes a casing that defines a diffusion chamber. A combustion liner is disposed within the diffusion chamber and defines a combustion chamber the combustion liner is spaced apart from the casing such that a passageway is defined between the combustion liner and the casing. A fuel cell assembly is disposed in the passageway. The fuel cell assembly includes a fuel cell stack that has a plurality of fuel cells each extending between an inlet end and an outlet end. The inlet end receives a flow of air and fuel and the outlet end provides output products to the combustion chamber. The fuel cell assembly further includes an electrical circuit that is electrically coupled to the plurality of fuel cells and that extends through the casing.
US12240610B2	Inversion-formed double-walled tube and energy absorbing inversion tube assembly An inversion-formed double-walled tube includes an outer tube having an outer wall thickness, an inner tube disposed inside the outer tube and having an inner wall thickness, and a transition portion connecting the inner tube and the outer tube. In this arrangement, at least one of the inner and outer wall thicknesses varies along a length of the double-walled tube. The inversion-formed double-walled tube may be configured as an inversion tube type energy absorber and as an energy absorbing inversion tube assembly.
US12240605B2	Systems and methods to control aerial distribution of materials A method for emitting a fluid from a fluid dispersal system includes determining a desired distribution profile for the fluid, identifying a plurality of sections of the desired distribution profile, and determining, for each section of the plurality of sections of the desired distribution profile, an amount of fluid required from each nozzle assembly of the plurality of nozzle assemblies needed to deposit fluid according to the desired distribution profile within the corresponding section. The method also includes determining a target emission rate of the fluid from each nozzle assembly of the plurality of nozzle assemblies based on the determined amount of fluid required from each nozzle assembly, and controlling an operating parameter of a valve assembly of each nozzle assembly to obtain the respective target emission rate from each nozzle assembly.
US12240603B1	Oblique all-wing vehicle An oblique all-wing (OAW) vehicle and methods are described where the OAW vehicle has a unique configuration and can be used to, for example, launch a payload. The OAW vehicle can include an elongated airfoil body with a longitudinal axis, a top surface, a bottom surface, a first longitudinal end, a second longitudinal end, a first longitudinal edge at a first juncture between the top surface and the bottom surface, and a second longitudinal edge at a second juncture between the top surface and the bottom surface. The elongated airfoil body has an airfoil-shaped cross-section, with the first longitudinal edge defining a leading edge and the second longitudinal edge defining a trailing edge. A rocket engine or other propulsion device is mounted to the elongated airfoil body at the first longitudinal end.
US12240600B2	Electric tiltrotor aircraft Embodiments include an aircraft comprising a fuselage; a wing connected to the fuselage; and first and second propulsion systems connected to the wing on opposite sides of the fuselage, wherein at least a portion of each of the first and second propulsion systems and at least a portion of the wing are tiltable between a first position in which the aircraft is in a hover mode and a second position in which the aircraft is in a cruise mode, wherein each of the propulsion systems includes pylon and a rotor assembly comprising a plurality of rotor blades.
US12240599B2	Systems and methods for lifter motor cooling in EVTOL aircraft A VTOL aircraft includes a plurality of lift propellers configured to rotated by lift motors to provide vertical thrust during takeoff, landing and hovering operations. The lift propellers are configured to generate a cooling airflow to cool the lift motors during use. During a cruise operation when the VTOL aircraft is in forward motion, the lift propellers may be stowed in a stationary position. Therefore, the cooling airflow may be reduced or eliminated when it is not needed.
US12240598B2	Aircraft wing assembly with integrated ducted fan and louvers having a rotational actuator An aircraft includes a wing having an integrated ducted fan. The ducted fan is equipped with inlet louvers and outlet louvers. The inlet louvers are adjustable between an open position and a closed position by an actuating mechanism.
US12240597B2	Aircraft with wing having integrated ducted fans An aircraft includes a wing with integrated ducted fans and ribs. Each respective ducted fan comprises a duct ring, a guide grille arranged within the duct ring, and an electric motor supported by the guide grille. The ribs are integrated into the guide grille. Each respective electric motor can be cylindrical, and the ribs can run tangentially along the electric motors.
US12240594B2	Aircraft landing gear comprising a spring opposing rotation between upper and lower elements of the landing gear An aircraft undercarriage includes an upper element for connecting to an aircraft structure and a lower element carrying an axle. The lower element is mounted to be movable in translation relative to the upper element along a longitudinal axis, and a shock absorber is arranged to damp movements in translation of the lower element relative to the upper element.First and second portions of a spring are connected respectively to the upper element and to the lower element so that during movement in translation of the lower element relative to the upper element, the spring opposes any turning of the lower element relative to the upper element about said longitudinal axis.
US12240589B2	Linear actuator system A linear actuator for axially translating a control tube to change the pitch of rotor blades at a top portion of the control tube, the linear actuator including an outer sleeve fixed in a stationary position with the control tube extending through the outer sleeve, a screw nut connected by a threaded interface to the control tube, and an actuator motor coupled to the screw nut to rotate the screw nut and thereby translate the control tube.
US12240585B2	Aircraft security door and method and apparatus for security door handling The present disclosure provides an aircraft security door as well as methods, systems and apparatus for handling an aircraft security door. In one implementation, a method for installing an aircraft security door onto an aircraft is disclosed. The method includes transferring the aircraft security door to an aircraft service stair, supporting the aircraft security door by a bridge crane coupled to the aircraft service stair, positioning the aircraft service stair in proximity to a fuselage of the aircraft adjacent to an opening in the fuselage, positioning the aircraft security door relative to the opening using the bridge crane, and securing the aircraft security door to the opening.
US12240575B2	Virtual reality sports mask with precision three-dimension underwater navigation A sports mask is disclosed that includes either: a snorkel and a SCUBA unit; a color underwater camera; a 3D color underwater camera; an augmented reality display projected onto the lens; a co-axial breathing hose-to-scuba unit; computerized underwater navigation; non-GPS computerized underwater navigation; a computerized navigation system that combines visual edge recognition and inertia navigation; an optical transponder; or RF communications.
US12240573B1	Marine propulsion device with flexible conduit in lower unit A marine propulsion device has a powerhead, a driveshaft powered by the powerhead, a lower unit, and a propeller shaft supported in the lower unit and in torque transmitting relationship with the driveshaft. The marine propulsion device also has a steering column through which the driveshaft extends and to which the lower unit is coupled. The steering column is configured to rotate the lower unit with respect to the powerhead. There is a steering housing through which the steering column extends, the steering housing being stationary with respect to the powerhead. A flexible conduit, for example a wiring harness, extends through an aperture in the steering housing and through an aperture in the steering column. The flexible conduit has slack between the steering housing and the steering column.
US12240572B2	System and method for controlling motorized boat fender deployment and retrieval systems A system and method for precise and consistent control of automated systems for deployment of boat fenders. The system comprises a computing device, one or more sensors, a motor controller, and a motor driver for operating motorized systems for deployment and/or retrieval of boat fenders. Various embodiments of the system use sensors and corresponding compensators to adjust the time of operation of a motor of the motorized system to ensure that the boat fender is deployed and/or retrieved to the proper height.
US12240566B2	Modular offshore floating platform systems and methods for operating the same A modular floating platform system includes a detachable floating buoy providing a body tethered to a seafloor with a plurality of mooring lines and coupled to a subsea production system via one or more communication lines, and a plurality of floating surface facilities, each floating surface facility providing a standardized bottom interface matable with the detachable floating buoy. A latching mechanism individually couples each floating surface facility to the detachable floating buoy when each floating surface facility is individually mated to the detachable floating buoy. One or more communication couplings place each floating surface facility in communication with the subsea production system via the one or more communication lines when each floating surface facility is individually mated to the detachable floating buoy.
US12240563B2	Air supply system for a hull of a vessel and a vessel comprising the air supply system Disclosed is an air supply system (100) for supplying air to an outside of a hull (201) of a vessel (200). The vessel comprises an engine. The air supply system comprises one or more turbocharger(s) (10) for supplying a compressed main air flow to the engine of the vessel via a respective first flow path (11A). The air supply system comprises an exhaust gas recirculation (EGR) system for recirculating exhaust gas into the compressed main airflow supplied to the engine via a second flow path (11B). The air supply system comprises a third flow path (11C) for supplying a sub-flow of compressed air to one or more Air Discharge Units (ADUs). The EGR system comprises a blower (31) arranged in the second flow path (11B) for supplying exhaust gas to the engine. The first flow path and the second flow path have a first connecting path (11AB) upstream of the blower (31) and a second connecting path (11BA) downstream of the blower. The third flow path is in fluid connection with the first flow path and the second flow path downstream of the blower, such that the sub-flow of compressed air can be extracted from the first flow path and/or the second flow path.
US12240562B2	Derailleur for human-powered vehicle A derailleur for a human-powered vehicle comprises a base member, a movable member, a linkage, an electrical actuator, a first biasing member, and a second biasing member. The base member is configured to be attached to a vehicle body of the human-powered vehicle. The movable member is configured to be movable relative to the base member in a first direction and a second direction different from the first direction. The linkage is configured to movably connect the movable member to the base member. The electrical actuator is configured to operatively move the movable member relative to the base member. The first biasing member is configured to deform if first external force is applied to move the movable member in the first direction. The second biasing member is configured to deform if second external force is applied to move the movable member in the second direction.
US12240559B2	Hub motor arrangements, systems, and methods Various hub motor arrangements, systems, and methods are disclosed. The hub motor arrangement may include a transmission assembly to provide increased torque. The transmission assembly may include a motor gear, a planetary gear, an idler gear, and a ring gear. The idler gear may be positioned farther away from an axis of rotation of the hub motor arrangement compared to the planetary gear. The motor gear may drive the planetary gear, the planetary gear may drive the idler gear, and idler gear may drive the ring gear. The rotation of the ring gear may rotate a housing of the hub motor arrangement to propel a vehicle incorporating the hub motor arrangement.
US12240558B2	Front structure of handlebar vehicle There is provided a front structure of a handlebar vehicle that allows clutch and brake operations to be easily performed with one hand of the rider, a clutch lever that activates a clutch device and a brake lever of a brake device that activates a rear-wheel brake being arranged around a grip provided at a side-end part of a steering handlebar. The brake device is provided with a hydraulic master cylinder provided with a cylinder hole that accommodates a piston, and a brake lever that activates the piston. A clutch grip operation part of the clutch lever and a brake grip operation part of the brake lever extend along the grip and are able to rotate in the same rotation direction, and the clutch lever is disposed higher in the body of the vehicle than the brake lever.
US12240557B2	Draw-bar box-type quickly folding micro electric vehicle Disclosed is a draw-bar box-type quickly folding micro electric vehicle, comprising of a seat frame assembly (1) that is horizontally arranged, the top surface of which is provided with a foldable backrest. A pair of symmetrically arranged rear wheel assemblies (2) are arranged at a position, close to a rear of the vehicle, on the bottom surface of the seat frame assembly (1), and two vertically downward first connecting posts (101), which are provided near the front of the lower end of the seat frame assembly (1). A footrest assembly (4) is hinged to the lower ends of the two first connecting posts (101) through the first connecting assemblies (3). The footrest assembly (4) is arranged parallel to the seat frame assembly (1), and the plane of the footrest assembly (4) is lower than the plane of the seat frame assembly (1). A steering column assembly (5) is hinged at the end of the footrest assembly (4) away from the seat frame assembly (1), and a front wheel assembly (6), with a power device, is attached at the lower end of the steering column assembly (5). A very low footrest assembly (4) is hinged to the seta frame assembly (1) by means of the first connecting assembly (3), so that the user does not need to raise their legs to use the vehicle. Thus, use of the vehicle is convenient and safety risks are reduced.
US12240554B2	Application server for managing electric bikes using Artificial Intelligence and method thereof An application server for managing electric bikes using Artificial Intelligence (AI) is disclosed. For each of a plurality of electric bikes, the application server is configured to process user information associated with a user using an electric bike from the plurality of electric bikes, sensor information associated with the electric bike, and path information associated with a path being used to ride the electric bike. The application server is further configured to determine whether information states of at least one of the user information, the sensor information, or the path information are deviating from associated predefined thresholds. In response to determining at least one deviation, the application server is configured to generate, an alert signal and transmit a deactivating signal to the at least one electric bike to progressively curtail at least one functioning of the at least one electric bike in response to determining at least one deviation.
US12240551B2	Steering method and steering system for an industrial truck A steering method of an industrial truck. The industrial truck comprises a drive, at least three steerable wheels, at least one steering setpoint value transmitter which steers at least one of the at least three steerable wheels, a steering computer which provides angle setpoint values, and an electrical power electronics unit which supplies electrical energy to a steering motor associated with the at least one steered wheel. The method comprises steering, via the at least one steering setpoint value transmitter, the at least one steered wheel, detecting angular positions of the at least one steered wheel, providing the angle setpoint values via the steering computer, comparing the angular positions of the at least one steered wheel with the angle setpoint values provided via the steering computer so as to determine a setpoint/actual value difference, and controlling the electrical power electronics unit based on the setpoint/actual value difference.
US12240544B2	Reconfigurable walking robot A robotic device is described. The robotic device includes segments and arms connected to a platform. A machining or another processing tool can be coupled to the platform. The segments can have one end attached to the platform and the other end attached to an attachment device. The attachment device can include an attachment surface/mechanism that can attach to a workpiece.
US12240541B2	Modular tracked vehicle A technique for a modular tracked vehicle that can be reconfigured as needed to address different requirements and use cases. The modular tracked vehicle includes a chassis hull that allows interchangeable components to be connected thereto. The interchangeable components include interchangeable final drives which drive the vehicle's tracks. The chassis hull stores an energy reservoir, such as a battery or fuel tank, and the final drives include at least a gear box and drive axle. Different final drives may be provided for different torque levels, speed levels, energy sources, and or other specifications, and the final drives may be swapped based on mission requirements. Other components of the modular tracked vehicle may be interchangeable, as well. The technique may be provided, for example, as a modular tracked vehicle, a platform for a modular tracked vehicle, and/or as a method for use with a modular tracked vehicle.
US12240537B2	Steering control device A steering control device includes a base axial force calculator, a limiting axial force calculator, and a final axial force calculator. The limiting axial force calculator includes a steering angle holder, a reference angle calculator, a final difference calculator, and an axial force calculator. The steering angle holder is configured to hold a steering angle at the time of limiting a turning operation of the turning wheels when the turning operation is limited. The reference angle calculator is configured to calculate a reference angle. The final difference calculator is configured to calculate a final difference which is a final difference between the reference angle and the current steering angle. The axial force calculator is configured to calculate a limiting axial force based on a value of the final difference.
US12240536B2	Control device and control method for electric power steering apparatus, and motor module In a control device to control a motor in an electric power steering apparatus including the motor, processor executes, according to a program calculation of a target assist torque by performing proportional integral (PI) control based on a target steering wheel angle and a steering angle, and control of the motor based on the target assist torque. A gain of an integrator used for integral (I) control of the PI control is variable.
US12240535B2	Headwind/crosswind air jet shield Various embodiments are directed to an air jet shield. The air jet shield may include a support frame configured to attach to a vehicle utilizing a set of security straps. Sets of V-shaped and concave air ducts may be horizontally and vertically coupled to the support frame, respectively. Each of the air ducts may have a decreasing cross-sectional area and include (i) an inlet that receives air from a surrounding environment during a travel of the vehicle into a headwind or crosswind and (ii) an outlet that dispenses the air received from the inlet as a free air jet. Upon entering a headwind or crosswind, the free air jet creates a wind shear causing rotation at an increased velocity. Within the free air jet and surrounding the vehicle, static air pressure and wind velocity is decreased, thereby causing a reduction in aerodynamic drag during travel.
US12240534B2	Work vehicle A work vehicle includes: a carrier box including: a floor panel; a pair of left and right side panels; and a rear gate supported by the floor panel in such a manner as to be capable of being opened and closed, the side panels being provided with an engagement section to which a height extension is detachably attachable, the rear gate including: a first panel connected with the floor panel in such a manner as to be movable rotationally; and a second panel connected with the first panel in such a manner as to be movable rotationally, wherein attaching the height extension to the engagement section and positioning the second panel over the first panel provides an additional height for both of the side panels and the rear gate.
US12240533B2	Tailgate deactivation system A tailgate deactivation system. A switch includes two terminals configured to be electrically coupled to a tailgate power circuit that supplies power to at least a portion of a tailgate of a vehicle, and an actuator configured to electrically couple the two terminals in an on state to allow power to flow in the tailgate power circuit, and to electrically decouple the two terminals in an off state to inhibit power from flowing in the tailgate power circuit.
US12240532B2	Foldable vehicle A foldable vehicle may include a chassis comprising a static support, a dynamic chassis frame that includes at least two substantially opposite frame parts and a folding mechanism for decreasing or increasing a distance between the at least two substantially opposite frame parts across a lateral axis of the vehicle between a folded state and an unfolded state; and a controller to control the folding mechanism.
US12240531B2	Steering device A steering device has a rib formed on a housing. The rib includes a first rib and a second rib intersecting with the first rib. When, in the two ends of the first rib, an end close to an intersection portion is defined as one end, the first rib includes a brittle portion which has reduced strength in comparison with those of the other portions and which is provided between the intersection portion and the one end.
US12240527B2	Inflatable-based process for controlling structural foam reinforcement molding A structural component for a vehicle includes a component including an interior surface defining a first hollow passage and a structural reinforcement contacting the interior surface of the component. The structural reinforcement and component define a cross-section and the structural reinforcement partially fills the cross-section. A process for forming the structural component including inserting a bladder into the first hollow passage defined by the interior surface of the component and inflating the bladder in the first hollow passage, forming a cavity between the bladder and the interior surface, filling the cavity with a polymer resin, and foaming the polymer resin. A system for forming a structural component for a vehicle includes a component including a first hollow passage defined by an interior surface of the component, a bladder insertable into the first hollow passage of the component, and a supply line connected to an interior of the bladder.
US12240522B2	Real-time path planning method for intelligent driving taking into account dynamic properties of high-precision vehicles The present invention provides a real-time path planning method taking into account dynamic properties of vehicles; the method includes a calculation without connecting to internet of a reachable set and an online path planning; in the calculation without connecting to internet of the reachable set, all vehicle safety states are traversed by means of the vehicle model and the wheel model, thereby predicting the position set capable of being reached by the vehicle at a next moment; in the online path planning, by means of calculating the position set capable of being reached by the vehicle at the next moment with connecting to internet, non-linear dynamic constraints are provided for the exploration of the artificial potential field method, achieving the purpose of real-time planning while taking into account dynamic properties of the vehicles.
US12240518B2	Baby stroller with a folding mechanism triggered by a child carrier A baby stroller is provided and includes a stroller frame and a child carrier. The stroller frame includes two supports, a first fixing component, a second fixing component and a locking component. The first fixing component and the second fixing component are fixed on one and the other one of the two supports, respectively, and pivotally connected to each other. The locking component is movably disposed on the first fixing component and configured to engage with the second fixing component for restraining a folding action of the stroller frame. The child carrier is disposed on the stroller frame and pivotable relative to the stroller frame. The child carrier is for providing a releasing force to the locking component for disengaging the locking component from the second fixing component to allow the folding action of the stroller frame during a pivotal movement of the child carrier relative to the stroller frame.
US12240516B2	Brake operating arrangement A brake operating arrangement (18) comprises a cam member (22) operable on a brake mechanism (36) for braking a wheel (34). The brake mechanism (36) is movable between a braking condition and a non-braking condition. The cam member (22) is rotatable to move the brake mechanism (36) to the braking condition. The brake operating arrangement (18) further includes a drive member (44) movable in drive and return directions; and a ratchet mechanism (46) to rotate the cam member (22) when the drive member (44) is moved in the drive direction. The ratchet mechanism (46) is connected to the drive member (44) and the cam member (22).
US12240512B2	Fixed signage and method for use of same A fixed signage (10) and method for use of the same are disclosed. In one embodiment, a housing (22) having a window (24) is sized to house a sign (26) therein. A closure assembly (32), under the power of an actuator (112), is installed in the housing (22) to support a cover material (34). The cover material (34) is moveable by a moveable closure member (138) between a fully retracted position whereat the cover material (34) is contained within the housing (22) such that the window (24) is exposed to a fully extended position whereat the cover material (34) covers at least a portion of the window (24). A command signal (180) may be received via a transceiver (160) to remotely control the actuator (112) and cover material (34). A signal sensor (60) within the housing (22) indicates the location of the cover material (34).
US12240509B2	Failure determination device, brake control device, and failure determination method A failure determination device includes an acquirer to acquire pressure values of air springs provided to bogies included in a vehicle to support a vehicle body included in the vehicle, a compensator to perform compensation of the pressure values of the air springs depending on the position of the vehicle, and a determiner to determine, based on the pressure values of the air springs compensated by the compensator, whether any failure occurs in the air springs.
US12240507B2	Mid of train unit A mid of train (MOT) mobile unit for use with a train is provided. The MOT mobile unit comprises a first hose for mounting the MOT mobile unit between first and second railway cars of the train located near a middle of the train and a radio for communications with an end of train (EOT) unit disposed on one end of the train and for communications with a head of train (HOT) unit disposed on other end of the train. With the first radio, the MOT mobile unit provides a repeater device functionality for communicating between the EOT unit and the HOT unit. The MOT mobile unit is configured to receive a power from a brake line of the train that runs a length of the train, wherein the power is derived from a compressed air in the brake line by means of an air-powered generator that recharges a battery.
US12240506B2	Train integrity detection system based on Beidou short message communication The invention relates to a train integrity detection system based on Beidou short message communication, which comprises a vehicle-mounted ATP host, a train rear device and a ground RBC device, wherein the vehicle-mounted ATP host communicates with both the train rear device and the ground RBC device, the vehicle-mounted ATP host and the train rear device each comprise a main control unit, and a wind pressure detection module, a wireless communication module, a speed measurement module and a satellite positioning module which are connected with the main control unit, and the vehicle-mounted ATP host and the train rear device also each comprise a Beidou short message communication module connected with the main control unit. Compared with the prior art, the invention has the advantages of strong communication jamming resistance and short response time.
US12240505B2	Low maintenance rail monitoring probe An ultrasonic probe for non-destructive testing of a rail, said probe comprising a housing; an insert comprising an ultrasonic transducer and a polycarbonate shoe having a face for contacting a rail; and a compressed spring for exerting a downward force on said insert; the system further comprising a plate with a restraining flange around an aperture to prevent the polycarbonate shoe from extending more than a preset fixed amount through the aperture.
US12240503B2	Method for controlling vehicle, electronic device, storage medium and vehicle A method for controlling a vehicle, an electronic device, a storage medium, and a vehicle are provided, related to a field of artificial intelligence technology, in particular to a field of autonomous driving and a field of computer vision. The method for controlling a vehicle includes: determining, in response to a request of switching to an autonomous driving mode, whether the vehicle is in a safe state; and controlling, in response to the vehicle being in the safe state, the vehicle to switch from a manual driving mode to the autonomous driving mode during travelling.
US12240501B2	Convolution operator selection A vehicle system includes one or more sensors configured to capture aspects of an environment and a computing device. The computing device is configured to receive information about the environment captured by the one or more sensors, determine one or more structures within the environment based on the received information, select a kernel that is parameterized for predicting a vehicle trajectory based on the one or more structures determined within the environment, and perform a convolution of the selected kernel and an array defining the environment, wherein the convolution predicts a future trajectory of a vehicle within the environment.
US12240500B2	Method of and system for predicting a maneuver of an object Methods and devices for generating data for controlling a Self-Driving Car (SDC) are disclosed. The method includes: receiving a section of a road map corresponding to surroundings of the SDC and at least one object, generating predicted trajectories including potential future location points of the at least one object, mapping the potential future location points on the section of the road map, computing a score for each of the potential future location points, computing an aggregated score from the scores corresponding to the potential future location points, and based on the aggregated score, determining a predicted location of the at least one object at the future instance of time.
US12240498B2	Vehicle control system, vehicle control method, and storage medium A vehicle control system is applied to a vehicle equipped with a magnetic sensor configured to detect a magnetic marker on a road. The vehicle control system executes a self-driving control by which self-driving of the vehicle is controlled. The vehicle control system executes a retreat traveling control using the magnetic marker in response to the occurrence of an abnormality in at least part of components and functions necessary for the self-driving control. The magnetic marker provides guidance information by which the vehicle is guided to a safe area. In the retreat traveling control using the magnetic marker, the vehicle control system acquires the guidance information from the magnetic marker detected by the magnetic sensor and causes the vehicle to travel toward the safe area and stop at the safe area based on the guidance information thus acquired.
US12240496B2	Autonomous vehicle navigation in response to a closed railroad crossing A control device associated with an autonomous vehicle receives sensor data and detects that the autonomous vehicle is approaching a railroad crossing based on the sensor data. The control device determines that the railroad crossing is closed from the sensor data. The control device determines one or more re-routing options from map data. The control device determines whether at least one re-routing option reaches a predetermined destination of the autonomous vehicle. In response to determining that the at least one re-routing option reaches the predetermined destination, the control device selects a particular re-routing option based at least on determining that the autonomous vehicle is able to travel according to the particular re-routing option autonomously. The control device instructs the autonomous vehicle to re-route according to the particular re-routing option.
US12240493B2	Vehicle controller, computer-readable medium storing vehicle control program, and vehicle control method A vehicle includes a sideslip preventing function of preventing a sideslip of the vehicle by separately adjusting a longitudinal force applied to each of the wheels. A controller controls the vehicle based on requests input from a driver assistance device, thereby causing the vehicle to travel autonomously. The controller calculates wheel lateral force request values based on the requests input from the driver assistance device. The wheel lateral force request values are request values of lateral forces acting on the respective wheels. The controller, when a behavior of the vehicle is in an oversteer state in a case in which the sideslip preventing function is failing, limits the wheel lateral force request values for the front wheels to values less than or equal to a first lateral force limit value, which is a limit value of the lateral force that can act on the rear wheels.
US12240487B2	Platform for perception system development for automated driving systems The present invention relates to methods and systems that utilize the production vehicles to develop new perception features related to new sensor hardware as well as new algorithms for existing sensors by using federated learning. To achieve this, the production vehicle's own worldview is post-processed and used as a reference, towards which the output of the software (SW) or hardware (HW) under development is compared. Through this comparison, a cost function can be calculated and an update of the SW parameters can be locally updated according to this cost function.
US12240483B2	Systems and methods to increase driver awareness of exterior occurrences Systems and methods are provided for increasing driver awareness of external audible and visual alerts. The external alerts may be detected by external sensors of a vehicle. Systems may use internal sensors to determine whether a driver of the vehicle appears aware of the external alert or whether the external alert is detectable inside the vehicle. If the driver does not appear aware of the external alert, or the external alert is not detectable inside the vehicle, the vehicle may broadcast an internal alert to the driver. The internal alert may be one or more of a visual alert, an audible alert, or a tactile alert.
US12240480B2	Methods and systems for providing trailer guidance Methods and systems are provided for providing guidance when reversing a vehicle towing a trailer. In one embodiment, a method includes: A method for providing guidance when reversing a vehicle towing a trailer, comprising: receiving, from a camera of the trailer, image data associated with an environment of the vehicle; determining, by a processor, that the camera of the trailer is at least one of partially and fully underwater; in response to the determining, determining, by the processor, at least one of underwater image data and underwater guideline data based on a correction factor associated with the water and the image data; and generating, by the processor, display data based on the at least one of underwater image data and underwater guidelines data.
US12240478B2	System for remote calibration and testing of a vehicle and a method thereof A system is for remote calibration and testing of a vehicle including a plurality of sensors and a data collection and transmission unit (“DCTU”). The system includes a receiving station and at least one virtual reality station. The receiving station is configured to establish a communication gateway between the DCTU and the at least one virtual reality station. The virtual reality station is configured to give a virtual vehicular experience by rendering data received from the DCTU on a plurality of actuators and a digital twin of the vehicle. Based on a physical experience and a recorded output in the at least one virtual reality station, an expert provides feedback to the DCTU via the receiving station for calibration and testing of the vehicle.
US12240477B2	System and method of enabling a user to retrofit a vehicle with at least one vehicle product A vehicle controller programming system is provided for enabling a user to program a vehicle controller for a vehicle that is being retrofitted with the vehicle controller. The system comprises a data storage unit for storing a database of a plurality of configurators and a corresponding database of a plurality of vehicle product portfolios. Each configurator and its corresponding portfolio are associated with a specific vehicle specification. The system also comprises a user interface unit for (i) receiving a set of vehicle characteristics that is associated with the vehicle, (ii) selecting one of the configurators and its corresponding portfolio based upon the set of vehicle characteristics, and (iii) creating a job based upon the selected configurator and its corresponding portfolio to enable a user to execute the job to program the vehicle controller.
US12240473B2	Carrier transport vehicle personal sensor zone A processing system deployed in a carrier transport vehicle may establish a wireless communication session with a mobile device of a user, assign a zone of the carrier transport vehicle to the user, the zone including a plurality of network-connected devices, obtain a user profile from the mobile device of the user, determine at least one biometric sensor accessible via the mobile device of the user, obtain biometric data of the user from the at least one biometric sensor accessible via the mobile device of the user, determine a condition of the user based upon the biometric data, identify at least one adjustment to at least one of the plurality of network-connected devices in response to the condition of the user that is determined and the user profile, and apply the at least one adjustment to the at least one of the plurality of network-connected devices.
US12240471B2	Systems and methods for optimizing coordination and communication resources between vehicles using models System, methods, and other embodiments described herein relate to coordinating and optimizing prediction by a model using intermediate data and vehicle-to-vehicle (V2V) communications that improves bandwidth utilization. In one embodiment, a method includes processing acquired data, by a subject vehicle using a prediction model, to execute a vehicle task associated with navigating a driving scene. The method also includes extracting processed data according to the acquired data from intermediate activations of layers within the prediction model according to a cooperation model. The method also includes quantifying relevancy of the processed data, for a target vehicle, to select a subset using the cooperation model. The method also includes communicating the subset to a selected vehicle having the prediction model for additional prediction according to the relevancy and available resources to transmit the subset.
US12240470B1	Method for driving behavior modeling based on spatio-temporal information fusion Provided is a method for driving behavior modeling based on spatio-temporal information fusion, relating to the field of driving behavior simulations. The method includes: constructing a driving behavior model, where the driving behavior model includes a spatial information encoding network, a temporal information encoding network, a feature fusion network, and a feature decoding network, with the feature fusion network being connected to both the spatial information encoding network and the temporal information encoding network, and the feature decoding network being connected to the feature fusion network; determining a future trajectory sequence of a target main vehicle at future time points based on the trained driving behavior model according to spatial information and temporal information of the target main vehicle, where the target main vehicle is controlled to travel according to the future trajectory sequence at the future time points.
US12240469B2	Occupant state detection device and occupant state detection method Included are: a captured image acquiring unit to acquire a captured image obtained by imaging an occupant; a temperature image acquiring unit to acquire a temperature image indicating a temperature of a surface of a body of the occupant measured in a non-contact manner; a motion detection unit to detect a motion of the occupant on the basis of the captured image; a temperature detection unit to detect a temperature of a hand of the occupant on the basis of the temperature image; and an awakening level estimating unit to estimate an awakening level of the occupant on the basis of the motion of the occupant detected by the motion detection unit and the temperature of the hand of the occupant detected by the temperature detection unit.
US12240467B2	Apparatus, method, and computer program for monitoring driver A driver monitor includes a processor configured to: detect the posture of a driver of a vehicle from an image of the interior of the vehicle generated by a camera provided on the vehicle, determine that the driver's condition is abnormal, when the detected posture satisfies an abnormality determining condition, detect an unusual sound made by the driver of the vehicle, based on a voice signal of the interior of the vehicle obtained by a microphone provided on the vehicle, and make the abnormality determining condition for the case where the unusual sound is detected less strict than an abnormality determining condition for the case where the unusual sound is not detected.
US12240466B2	System and method for identifying a change in the operator of a vehicle A system for identifying a change in the operator of a vehicle includes a controller configured to determine, during operation of the vehicle by a current operator of the vehicle over a period of time, a plurality of values for at least two variables associated with the current operator. The controller correlates the values for the two variables to form a plurality of data points which together form a point cloud associated with the current operator. The controller performs a comparison of the point cloud to a point cloud stored in a memory and associated with a prior operator of the vehicle and determines, responsive to the comparison, whether the current operator of the vehicle is the prior operator of the vehicle.
US12240461B2	Driving support apparatus The driving support apparatus performs deceleration control of the vehicle. The driving support apparatus includes: a sensitivity setting unit configured to set an actuation sensitivity of a deceleration control; a deceleration execution unit configured to execute the deceleration control based on the actuation sensitivity; and a brake operation detection unit configured to detect a brake operation by a driver. The sensitivity setting unit changes the actuation sensitivity based on a control execution count which is the number of executions of the deceleration control and a driver operation count which is the number of operations of the brake operation.
US12240460B2	Method and control unit for the satellite-based localization of a vehicle in a map-based reference system A method for the satellite-based localization of a vehicle in a map-based reference system. A trajectory in a map-based reference system is determined at regular time intervals, on which trajectory the vehicle is to be brought to a stop at least partially automatically in a defined emergency, and are stored in a circular buffer. In the defined emergency and in the event of failure of the at least one camera used for the full localization, an emergency trajectory is selected from the trajectories stored in the circular buffer. An initial vehicle position in the map-based reference system is determined based on the emergency trajectory. A vehicle orientation is ascertained based on a continuously acquired yaw rate of the vehicle. The stretch of route traveled by the vehicle is ascertained based on position data of the vehicle that are acquired in a satellite-based manner.
US12240459B2	Driving assistance method and driving assistance device The present invention pertains to driving assistance method and device by which an automobile can be parked at a location near a target parking location when carrying out ACC. During deceleration control via ACC, when a predicted parking location is closer than a target parking location by at least a prescribed threshold value, a parking location is adjusted by causing a state change from a first state, in which deceleration control is carried out, to a second state, in which acceleration control is carried out.
US12240453B2	Activating adaptive cruise control A computer is programmed to, in response to a navigation feature being active for a route, prompt an operator of the vehicle to activate a driver-assist feature of the vehicle. For example, the computer can output a message via a user interface indicating that the driver-assist feature is available to be used. The computer is further programmed to receive an input indicating a destination, determine the route for the vehicle from a current location of the vehicle to the destination, and activate the navigation feature to output guidance instructing the operator to follow the route.
US12240444B2	Drive assistance device and drive assistance method This drive assistance device comprises an ACC unit, an abnormality detection unit for detecting an abnormality from a detector used to perform ACC, and a vehicle stop control unit for performing control to stop an ego vehicle when an abnormality is detected by the abnormality detection unit and an inter-vehicle distance to a preceding vehicle satisfies a certain condition.
US12240443B2	Vehicle control apparatus, vehicle control method, and vehicle control system A vehicle control apparatus acquires a first collision risk based on a relative distance and a relative speed between an obstacle ahead of a vehicle and the vehicle, outputs a first control instruction for autonomously applying a braking force to the vehicle based on the first collision risk, acquires a second collision risk into which the first collision risk is updated after the braking force is autonomously applied to the vehicle, outputs a second control instruction for autonomously applying a force regarding steering to the vehicle based on the second collision risk, and outputs a third control instruction for controlling the braking force to be generated on a wheel portion of the vehicle based on the second collision risk after the force regarding the steering is autonomously applied to the vehicle.
US12240438B2	Contactor failure determination apparatus for vehicle To provide a contactor failure determination apparatus capable of appropriately determining failure of a contactor provided in a vehicle, a voltage sensor capable of detecting rising or dropping of a voltage of a second circuit including an external charger is provided. When an external charging request is made, a first control for closing each external charging contactor is executed, a second control for closing a pre-charge contactor is executed after execution of the first control, a third control for closing a second main contactor is executed after execution of the second control, and response to the voltage sensor detecting that the voltage of the second circuit has not risen after execution of the third control, it is determined that at least one of the external charging contactors has failed in an open state.
US12240432B2	Systems and methods for variable brake hold actuation and release Systems and methods are provided for variable actuation and release of a vehicle's brake hold mechanism/function. A brake hold device may be implemented as a “tuner” or controller that can connect to and override, e.g., the default functionality of an existing brake hold mechanism of a vehicle. Delays in exiting a brake hold state, repetitive actuation of an accelerator to exit a brake hold state, and other shortcomings associated with the conventional operation of brake hold mechanisms may be avoided by taking into account relevant vehicle operating conditions or environmental/road/traffic conditions.
US12240430B2	Method for operating a braking system for a motor vehicle and corresponding braking system A method for operating a braking system for a motor vehicle, including a service brake unit and the service brake unit is activated to generate a brake force on a wheel axle of the motor vehicle at least temporarily as a function of a setting of an operating element. The generation of the brake force is performed using a calibration data set stored in a control unit of the braking system. An identifier stored in the operating element is transmitted to the control unit and used for a compatibility check. If the compatibility check is successful, a configuration of the operating element takes place and a generic data set stored in the control unit is used as the calibration data set and an operating element-specific data set stored in the operating element is transmitted to the control unit and used as a calibration data set after the transmission.
US12240429B2	Brake state estimation device and vehicle equipped therewith, brake state estimating method, and recording medium storing program A brake state estimation device includes: a position acquisition section that acquires a position of a subject vehicle; and a state estimation section that estimates a state of deterioration of brake fluid for operating a hydraulic brake device of the subject vehicle, on the basis of humidity information corresponding to the position of the subject vehicle, and duration information expressing a duration of staying in an area that includes the position of the subject vehicle.
US12240427B2	Fast replenishing brake system A brake system includes a source of pressurized hydraulic fluid, a plurality of wheel brakes, and an iso/dump control valve arrangement associated with at least one wheel brake. A reservoir is connected to the source of pressurized fluid and to the iso/dump control valve arrangement. A fast-replenishing circuit includes a FR iso valve, a venting valve, and a replenishing check valve. The venting and replenishing check valves are interposed between the source of pressurized fluid and the reservoir. The FR iso valve is interposed between the source of pressurized fluid and the iso/dump control valve arrangement. When the source of pressurized fluid reaches a predetermined stroke position, the FR iso valve is energized to restrict movement of fluid from at least one iso/dump control valve arrangement to the source of pressurized fluid. The source of pressurized fluid is re-stroked to draw fluid from the reservoir through the replenishing check valve.
US12240425B2	Compact electromechanical brake An electromechanical drum brake comprises two brake segments intended to come into contact with a drum, and at least one actuator configured to apply the segments against the drum, and an electric motor configured to activate the actuator, the actuator comprising at least one member which is movable upon activation of the actuator, the movable member being movable between a braking position and a position beyond a release position, in which the segments are no longer in contact with the drum. The actuator comprises a stop which is arranged only in the actuator and against which the movable element bears when it assumes a position beyond the release position, and the motor powers the actuator until the movable element bears against the stop.
US12240414B2	Vehicle sensor control for optimized monitoring of preferred objects within a vehicle passenger cabin Upon detecting an absence of a user inside a passenger cabin of a vehicle, an object inside the passenger cabin is classified as one of preferred or nonpreferred. Upon classifying the object as preferred, a sensor is activated to monitor an environment outside the passenger cabin based on determining the object is visible from outside the passenger cabin. A priority level for the preferred object is determined based on data from the sensor, wherein the priority level is one of high or low. A vehicle component is actuated to reduce the priority level based on determining the priority level for the preferred object is high.
US12240413B2	Pretensioner tube for a belt tensioner A tensioner tube (18) for guiding a load transmission element (20) for a belt tensioner comprises an exit end (32) and a tube section (34) adjacent to the exit end (32), the tube section (34) being configured and arranged so that the longitudinal axis (L) of the tube section (34) is substantially tangent to the drive gear (14), wherein an elongate projection (36) protruding into the interior of the tube, the longitudinal axis (I) of which is inclined in relation to the longitudinal axis (L) of the tube section (34), is formed in the tube section (34) adjacent to the exit end (32). A belt tensioner for a seat belt system comprises a pyrotechnically movable load transmission element (20) and a drive gear (14) which can be driven by the movable load transmission element (20). The load transmission element (20) is guided in a tensioner tube (18) of the above-mentioned type.
US12240411B1	Seat belt buckle, seat belt fastener, and vehicle steering wheel locking method A seat belt buckle for a seat belt fastener and a vehicle steering wheel locking method. The seat belt buckle includes a housing, and a buckling assembly and a locking assembly mounted on the housing. The buckling assembly includes a buckling slider, a tripping button, and a stop slider. The locking assembly includes a limiting panel and a lock. When a latch plate is inserted in to a plate hole of the seat belt buckle, the latch plate engages with the buckling slider. When the lock is switched to a locking state, the limiting panel is driven to limit the tripping button to prevent the tripping button from being pressed, and the latch plate and the buckling slider from disengaging from each other.
US12240410B2	Drive device having a coupling device for a vehicle flap A drive device for a pivotable vehicle flap includes a flap part associated with the vehicle flap, a body part associated with a vehicle body and a hinge arrangement which hingedly connects the flap part and the body part. The hinge arrangement allows the flap part to be pivoted about a first axis of rotation for opening and closing the vehicle flap and about a second axis of rotation for raising the vehicle flap into a pedestrian protection position. The drive device further includes a first actuator for opening and closing the vehicle flap in normal operation, a second actuator for raising the vehicle flap into a pedestrian protection position and a coupling device for coupling the first actuator to one of the flap part and the vehicle flap, including a fastening part which is fixedly connected to the one of the flap part and the vehicle flap. The coupling device includes at least one first lever coupled to the first actuator. During normal operation of the coupling device, the first lever is releasably secured against rotation relative to the fastening part via a mechanical securing element.
US12240400B2	Side airbag device The present invention is provided with an inflator arranged on the occupant side of the side frame positioned on the side portion inside the seatback that generates expansion gas and an airbag that is expanded by the expansion gas and protects an occupant seated on the vehicle seat. The airbag includes a main chamber that deploys toward the front of the seatback, and a pre-chamber that houses the inflator inside and is connected to the occupant side of the main chamber. In addition, an internal tether having a front end part connected to the front portion of the pre-chamber and a rear end part connected to the rear portion of the pre-chamber are provided inside the pre-chamber.
US12240396B2	Vehicle audio and light signaling system and method of use A vehicle audio output device and light system accommodating sounding the vehicle audible output device and illuminating one or more vehicle exterior lights when a user-operated button is pressed. The electrical circuit includes a battery electrically connected to a horn and light computer. The computer includes a processor and an input/output interface. The system circuit further includes a user-operated button electrically connected to the battery, to a vehicle horn, and to an input port of the system computer. The system computer is electrically connected to a light relay module via an output port, and the light relay module is connected to a vehicle exterior light. The system computer processor can be programmed to illuminate or flash the exterior light as desired. The system may further include a vehicle audio output device and light system switch and may also include a vehicle main computer electrically connected to the light relay module.
US12240395B2	Electrical junction box An electrical junction box includes: a bus bar; a frame that holds the bus bar; and a temperature detection member that detects the temperature of the bus bar, wherein the temperature detection member includes a detection main body part capable of detecting temperature, and a wiring part extending from the detection main body part, and is held by one or more holding parts, the frame is integrally molded in a shape including a frame part surrounding a periphery of at least a part of the bus bar that includes a detection target portion to be subjected to detection by the temperature detection member, and at least one holding part of the one or more holding parts, and the at least one holding part of the one or more holding parts is provided so as to be located inward of the frame part.
US12240394B2	Motor vehicle having a plurality of control devices which provide different vehicle functions in the motor vehicle and method for configuring the control devices and control device A motor vehicle has a plurality of control devices which are designed to provide a particular vehicle function in the motor vehicle. The vehicle functions of the control devices differ. The control devices are connected by a common bus line which is led successively through a respective communications circuit of the control devices, wiring the control devices successively into a daisy-chain circuit. Each of the vehicle functions is implemented in each of the control devices. A processor circuit is designed to determine a position specification which specifies a position of the particular control device within the daisy-chain circuit and, according to the determined position specification, to select a vehicle function allocated to the position from the implemented vehicle functions and to provide the selected vehicle function in the motor vehicle for activation.
US12240389B2	Wiring member A wiring member includes: a linear transmission member that includes an electric wire; a connector housing; an outer armor member; and a cover member that is provided between the connector housing and the outer armor member in a lengthwise direction of the electric wire, and attached to an outer circumferential portion of the linear transmission member. The cover member and the linear transmission member are relatively movable in the lengthwise direction of the electric wire, and the connector housing and the outer armor member restrict a movement of the cover member in the lengthwise direction of the electric wire. The cover member is an elastic member, and includes an elastic cylindrical portion that is compression-deformable in a lengthwise direction of the cover member.
US12240385B2	Front image generation device for heavy equipment A device for generating a front image for heavy equipment is presented, which is configured to generate a combined front image including an object in an area obstructed by a visual field obstructing component by combining an image of a preset area in a front image of a second view to a front image of a first view. The presented device for generating a front image for heavy equipment generates a first front image and a second front image by photographing the front from the upper portion and lower portion of the heavy equipment, and generates a combined front image by combining a part of the second front image to a partial area of the first front image, so that the areas thereof located at a set distance forward from the front end of the visual field obstructing component coincide with each other.
US12240381B2	Frameless interior rearview mirror assembly A vehicular frameless interior rearview mirror assembly includes a mirror head and a mounting portion. The mirror head includes a mirror reflective element and a mirror casing. The mirror reflective element includes a glass substrate having a planar front side and a planar rear side. No portion of the mirror casing overlaps the planar front side of the glass substrate of the mirror reflective element. A camera is disposed within the mirror casing behind the mirror reflective element. With the mounting portion of the mirror assembly mounted at an in-cabin side of a windshield of a vehicle, the camera views a driver of the vehicle, and when the mirror head is moved by the driver to adjust a rearward view of the driver, the camera moves in tandem with movement of the mirror head. The camera is part of a driver monitoring system of the vehicle.
US12240378B2	Light emitting device A light emitting device to be mounted on a mount surface of a vehicular compartment includes a housing including a first section having an air intake hole and a second section having an air discharge hole, a cooling fan device arranged in the first section, and a light emitter arranged in the second section. The housing further includes a discharge cavity having the discharge hole. The light emitter and the cooling fan device are arranged in a first arrangement direction laterally along the mount surface. The light emitter includes a board member and a light emitting element. The board member has a first surface that is opposite the mount surface and a second surface that is an opposite surface of the first surface and on which the light emitting element is mounted. The first surface of the board member is defined as a portion of the discharge cavity.
US12240376B2	Active occupant status and vehicle operational status warning system and methods Systems and methods including at least one internal sensor attached internally to a vehicle, at least one external sensor mounted externally to the vehicle, wherein the external sensor detects at least one of a distance of other vehicles, a speed of other vehicles, driving patterns of other vehicles, and weather conditions; and at least one display configured to receive input from the internal sensor and the at least one external sensor, wherein the at least one display notifies a driver of an adjacent vehicle and/or a system controlling an adjacent manually-driven, semi-autonomous, or self-driving car of at least one of the occupation status of the vehicle, operational status of the vehicle, weather conditions, changing driving behaviors, when the adjacent vehicle exceeds a speed threshold, and/or when the distance between the vehicle and the adjacent vehicle falls below a minimum separation distance.
US12240369B2	Cup holder assemblies and vehicles including same Disclosed herein are assemblies for cup holders which include a cup holder body defining a receptacle, and a compressible bumper including a contact portion and a tab extending from the contact portion and through a slot formed in the cup holder body to retain the contact portion of the compressible bumper within the receptacle of the cup holder body. Further disclosed herein are assemblies for a vehicle including a center console and a cup holder assembly provided within the center console, the cup holder assembly including a cup holder body defining a receptacle, and a compressible bumper including a contact portion and a tab extending from the contact portion and through a slot formed in the cup holder body to retain the contact portion of the compressible bumper within the receptacle of the cup holder body.
US12240361B2	Infant car seat An infant car seat is adapted for being installed on a seat carrier. The infant car seat includes a seat shell, a latch, a release unit, and a resilient member. The seat shell is formed with a receiving space having an opening. The latch is disposed in the receiving space, and is adapted for engaging with a ledge of the seat carrier. The release unit includes an actuating member operable to drive the latch to move from a rest position, where a portion of the latch protrudes out of the opening for engaging with the ledge of the seat carrier, to a retracted position, where the latch is retracted into the receiving space. The resilient member is connected between the seat shell and the latch for biasing the latch toward the rest position.
US12240358B2	Method for operating a vehicle seat device, vehicle seat device A method for operating a vehicle seat device for motor vehicles, which has a vehicle seat with a seat part and a backrest, associated with the seat part, and at least one actuator which is associated with the seat part and/or the backrest and by means of which the vehicle seat can be brought automatically into a sitting position and into a reclining position, wherein the movement takes place as a function of a desired position that can be specified by a user and of at least one detectable vehicle seat state. It is provided that a current temperature is monitored as the vehicle seat state and that if the monitored temperature falls below a limit temperature, the vehicle seat is brought into a sitting position or left in a current sitting position regardless of the desired position.
US12240357B2	Cushioned pad apparatus to indicate and alert presence of an unattended occupant within a vehicle A cushioned device configured to prevent an occupant of a vehicle from being left unattended. The device includes a cushioned pad with a pressure sensor, a dongle, and an optimal application for receiving a pressure signal detected by the cushioned device. The application and dongle capable of generating an audible noise and associated notifications when a predetermined distance between the cushioned portion and the dongle and/or application is too great indicating that the object on the cushioned pad is now unattended. Accordingly, this system utilizes the proximity of companion devices and detected pressure signal to determine unattended occupancy in a confined space.
US12240349B2	Systems and methods for estimating state of health of an energy storage device A system for determining a state of health (SOH) of an energy storage device comprises a controller configured to be coupled to the energy storage device. The controller is configured to determine a current value drawn by or supplied to the energy storage device over a predefined period of time. In response to the current value not satisfying a current threshold, the controller determines a current gain factor and determines an adjusted current value from the determined current value based on the current gain factor. The controller is configured to determine an estimated SOH of the energy storage device based on the adjusted current value, and indicate the estimated SOH on a user interface.
US12240347B2	Systems and methods for an integrated vehicle and structure charger Systems, methods, and other embodiments described herein relate to vehicle charging and supplying backup power to a structure while reducing system complexity (e.g., installation). In one embodiment, a system includes a charger including a charging circuit and a discharge circuit coupled to a charging connector for an electric vehicle (EV), and the charging connector is bi-directional. The system also includes that the charging circuit supplies an ingoing power from a main electric panel of a structure to the charging connector. The system also includes that the discharge circuit receives an outgoing power through the charging connector and splits the outgoing power in voltage levels using a transformer. The system also includes a manual transfer switch within the discharge circuit that feeds backup power using the voltage levels to a sub-panel for electrical circuits of the structure during a power interruption and the sub-panel is external from the charger.
US12240341B1	Controlling vehicles at a charging station A dense charging station for charging the battery may have lanes arranged in parallel, and each of the lanes may have sequential charging locations. A vehicle utilizing the charging station may position itself at the first available charging location, being receiving energy, and determine if a subsequent charging station becomes available in the lane, and then position itself at the subsequent charging location, once available. Multiple charging stations may be required to maintain a threshold power state for individual vehicles in a fleet of vehicles providing a service for a geographic region. A charging coordinator may determine when a battery of a vehicle does not satisfy a threshold power state and requires a recharge. Additionally, the charging coordinator may determine a candidate charging station from among multiple charging stations associated with the geographic region.
US12240340B2	Controlling electrical access to a lithium battery on a utility vehicle Techniques control a utility vehicle. Such techniques involve storing electric power in a lithium battery of the utility vehicle. Such techniques further involve operating a motor controller of the utility vehicle in a normal mode in which the motor controller provides electric power from a lithium battery of the utility vehicle to an electric motor of the utility vehicle to turn one or more ground engaging members of the utility vehicle. Such techniques further involve, after operating the motor controller in the normal operating mode, operating the motor controller in a walkaway mode in which the motor controller configures the electric motor to provide braking torque.
US12240339B2	Power supply device A power supply device includes a driving control device and an auxiliary control device, the vehicle including a main power source, an auxiliary power source, and a supply path, the supply path being a path configured to be opened and closed according to a state of a start switch of the vehicle. The driving control device is a device that controls a state of equipment installed in the vehicle and the auxiliary control device is a device that controls a state of the auxiliary power source. The driving control device is configured to execute a storage process, a permission signal transmission process, and an initial value process, and the auxiliary control device is configured to execute a permission signal reception process and a stop process.
US12240335B2	Greasing sleeve The invention concerns a method for greasing a contact wire for the electrical power supply of a pantograph of a rail vehicle comprising: inserting the contact wire into a passage opening of a base body extending in a longitudinal direction, a transverse direction perpendicular to the longitudinal direction and a height direction perpendicular to the longitudinal direction and perpendicular to the transverse direction, whereby the passage opening penetrating the base body in the longitudinal direction as seen from a front side to a back side as seen in the longitudinal direction, and accelerating the base body in the longitudinal direction so that the contact wire is moved through the passage direction, characterized by introducing grease into the passage opening through which the contact wire moves at a feed rate at which the introduced grease exits the passage opening at the back of the base body under a predetermined condition.
US12240333B2	Reducing switching-on and switching-off processes in an electric drivetrain A method (100) for operating a vehicle (1) with an electric drive-train (2), wherein this electric drivetrain (2) is fed via a DC voltage source (3) and a converter (4) for converting the DC voltage into a single-phase or multiphase AC voltage, comprising the steps: —it is detected (110) that the vehicle (1) is stopped; —it is checked (120) on the basis of at least one specified criterion (10) whether the vehicle (1) is expected to be stopped only briefly; —in response to the fact that the vehicle (1) is expected to be stopped only briefly, the vehicle (1) is transferred (130) from the ready-to-drive state into a disabled state, wherein in this disabled state the vehicle (1) is protected against unauthorized use but the converter (4) continues to be supplied with the DC voltage from the DC voltage source (3); —in response to the fact that the vehicle (1) is not expected to be stopped only briefly, at least one functional test of the electric drivetrain (2), said test being provided for powering down the electric drivetrain (2), is performed (140), and after the termination of this functional test the vehicle (1) is transferred (150) into a switched-off state, in which the vehicle (1) is secured against unauthorized use and the supply of the converter (4) from the DC voltage source (3) is interrupted.
US12240326B2	Method and device for operating a windshield display system with a covered display detection, and windshield display system A reflection display system for displaying a display image for a vehicle occupant of a motor vehicle by reflecting the display image on a windshield is provided. The system includes a display unit which is designed to display the display image on a display surface, a detection sensor system for detecting the displayed display image on the display surface, and a control unit which is designed to actuate the display unit for displaying purposes, ascertain detection information on the basis of the detected displayed display image, ascertain the presence of a foreign object on the display surface of the display unit on the basis of the displayed display image and on the basis of the detection information, and signal a disruption of the display if the presence of a foreign object on the display surface of the display unit has been ascertained.
US12240323B2	Vehicle control device and control method therefor The present invention provides a vehicle control device and a control method therefor. A vehicle control device according to one embodiment of the present invention comprises: an interface unit communicatively connected to a display unit provided in a vehicle; and a processor for controlling the display unit provided in the vehicle through the interface unit, wherein the processor receives destination information through the interface unit, acquires, from map information, spatial coordinates of a building corresponding to the destination information, and controls, on the basis of the spatial coordinates of the building corresponding to the destination information, the display unit so that a graphic object related to the destination information overlaps with the building and is displayed.
US12240319B2	Off-road utility vehicle An off-highway recreational includes a frame, a prime mover, a transmission, an intermediate shaft and a main shaft. The transmission is mechanically coupled to receive power from the prime mover and to provide mechanical power at a transaxle output shaft. The intermediate drive shaft is mechanically coupled to the transaxle output shaft, wherein the intermediate drive shaft has a first diameter. The main drive shaft is mechanically coupled to the intermediate drive shaft, wherein the main drive shaft has a second diameter that is greater than the first diameter.
US12240318B2	Multi-gear portal A portal assembly has a housing for attachment to the vehicle axle and enclosing a gear assembly having an input gear linked to the axle shaft for rotating around a first rotational axis and an output gear positioned within a second lower rotational axis that converts rotation of the input gear to rotation of the output gear. An output axle is driven by the output gear for transferring rotational force to a unit bearing located outside of the housing. The unit bearing is attached to and transfers rotational force to a wheel hub.
US12240317B2	Fuel pump module for a vehicle A fuel pump module for a vehicle includes: a pump positioned in a reservoir cup in a tank and configured to suction and discharge fuel from the reservoir cup; a mount plate mounted in an opening of the tank; a return valve on the mount plate and configured to pass return fuel, which is returned from an engine, into the tank; a shaft bracket connecting the mount plate and the pump in the tank and configured to fix the pump to the mount plate; a guide wall disposed on the shaft bracket to guide return fuel flowing in the tank through the return valve; and a channel disposed at the shaft bracket so that return fuel flows down and configured to discharge the return fuel into the reservoir cup.
US12240316B2	Reservoir cup assembly of LPG fuel tank for vehicle A reservoir cup assembly of an LPG fuel tank for a vehicle is configured to be installed on the fuel storage space side of the LPG fuel tank for automobiles, and includes a cup body disposed on the bottom side of the fuel storage space of the fuel tank and having a reservoir space for storing residual LPG fuel and a fuel supply formed on the reservoir space side of the cup body and inducing fuel from the fuel storage space side to the reservoir space side to a state in which fuel can flow in and remain stored.
US12240313B2	Motor vehicle cooling system with an electric coolant pump A motor vehicle cooling system with an electric coolant pump includes a housing with a pump shaft. The electric coolant pump includes an electric motor in a motor housing. The electric coolant pump is at least partially accommodated in the pump shaft. A clamping device including at least two clamping arms is attached to an upper side of the motor housing. The clamping arms are supported with free ends thereof on an inner side of the pump shaft to clamp the electric coolant pump to the housing.
US12240312B2	Tray and tray manufacturing method A tray (20) including a bottom wall (21) and a peripheral side wall (22) erected from an outer periphery of the bottom wall (21) includes a high-strength portion HT having a high tensile strength; and a low-strength portion LT having a tensile strength lower than that of the high-strength portion HT. The low-strength portion LT includes a recessed portion (C) having a corner portion (22C) in a first side wall inner surface (221a) and a second side wall inner surface (222a) which are adjacent to each other at a minor angle and a corner section (21C) on an upper surface (21a) of the bottom wall (21) having a minor angle to each of the first side wall inner surface (221a) and the second side wall inner surface (222a).
US12240310B2	Floor structure Provided is a structure of the floor of a vehicle having a battery pack mounted on the lower side of the floor, the structure including a floor panel constituting the floor; a floor tunnel extending in the front-rear direction of the vehicle on the middle portion of the floor panel; a lower dash panel disposed in front of the floor panel and the floor tunnel; and an electromagnetic wave shielding panel covering a corner where the floor panel, the floor tunnel, and the lower dash panel are connected to each other.
US12240309B2	Mobile home In the case of a travel trailer having a battery and an axle (13) or a tandem axle, the battery (9) is designed for supplying electricity to a travel drive of a towing vehicle and/or to an optional travel drive of the travel trailer during trailer travel in road traffic, and is arranged as a flat battery (9) below a floor of the travel trailer, in a vehicle frame (1), wherein the height of the battery (9) essentially corresponds to the height of the vehicle frame (1).
US12240307B2	Motor configurations for multiple motor mixed-speed continuous power transmission An electric powertrain includes a first electric motor that has an uninterrupted connection with a drive shaft of a vehicle. The electric powertrain further includes a second electric motor that has an interruptible connection with the drive shaft. In one form, this interruptible connection includes a clutch. The electric powertrain further includes a first gear train in the form of a first planetary gear and a second gear train in the form of a second planetary gear. In one form, the first electric motor and second electric motor are the same type of electric motor, and in another form, the first electric motor and second electric motor are different types of electric motors.
US12240305B2	Left-right wheel driving device In a left-right wheel driving device (10) including two motors (1, 2) that drive left and right wheels and a gear mechanism (3) that amplifies a torque difference between the two motors (1, 2) and transmits the amplified torques to the left and right wheels, respective, rotating shafts (1A, 2A) of the two motors (1, 2) are coaxially disposed. The left-right wheel driving device (10) further includes motor shafts (11) that are positioned between the rotating shafts (1A, 2A) coaxially with the rotating shafts (1A, 2A) and that are each provided with a motor gear (21), counter shafts (12) that are disposed in parallel to the motor shafts (11) and that are each provided with a first intermediate gear (22) meshing with the motor gear (21) and a second intermediate gear (23) having a diameter smaller than that of the first intermediate gear (22), and output shafts (13) that are disposed in parallel to the motor shafts (11) and that are each provided with an output gear (24) meshing with the second intermediate gear (23). The gear mechanism (3) is disposed on one end side of each of the output shafts (13) and one of the left and right wheels is disposed on the other end side of the output shaft (13).
US12240302B2	Tarpaulin protection devices A flutter reducer for protecting at least partially a tarpaulin defining a tarpaulin rear end edge from flutter induced damages when the tarpaulin is secured laterally across a container moved at speed, the container defining a container aperture delimited by an aperture peripheral edge. The flutter reducer is operatively coupled to the tarpaulin so that when the tarpaulin is extended across the container aperture configuration and the container is moved by the vehicle, the flutter reducer limits movements of the tarpaulin at its tarpaulin rear end edge to reduce flutter due to relative wind caused by movement through air of the container.
US12240301B2	Service hole cover and door wiring module Provided is a service hole cover covering a service hole formed in an inner panel in a vehicle door panel, the service hole cover including: a cover body part covering the service hole; and at least one catching part provided to protrude from the cover body part to a side of the inner panel, wherein the catching part is caught on the inner panel while at least a part of the service hole is opened.
US12240296B2	Electrical architecture for powering transportation refrigeration unit A power system architecture configured to power a transport refrigeration system (20) based on a determined an AC power requirement. The system (20) includes a generator power converter (164) configured to receive the generator three phase AC power (163) from an AC generator (162), and provide a generator DC power (165). The system (20) also includes a grid power converter (184) configured to receive the grid three phase AC power from a grid power source (182), and provide a grid DC power (185), an energy storage device (152), the energy storage device (152) operable to provide a DC power (157) and connected to a variable DC bus, and a power management system (190) operably connected to direct power (195) the TRU (26) based on at least the AC power requirement.
US12240295B2	Systems and methods for controlling a vehicle HVAC system Disclosed are climate systems for vehicles and methods for controlling the climate systems. In some implementations, a climate system includes: (1) a temperature sensor configured to measure a temperature within the compartment of the vehicle; (2) a first compressor powered by an engine of the vehicle to compress a refrigerant; (3) a second compressor driven by an electric motor to compress the refrigerant; and (4) a controller electrically coupled to the first compressor and the second compressor. The controller configured to: (1) calculate a thermal load of the compartment based on a difference between a desired temperature and a measured temperature; and, (2) based on the calculated load, selectively activate: (i) the engine, (ii) the first compressor, and/or (iii) the second compressor.
US12240291B2	Integrated thermal management system for vehicle An embodiment integrated thermal management system for a vehicle includes a main refrigerant line configured to circulate a refrigerant sequentially through a compressor, an inner condenser, an outdoor heat exchanger, and an evaporator, an integrated chiller configured to perform heat exchange between a first coolant flowing through a battery, a second coolant flowing through an electronic component, and the refrigerant, a gas injection refrigerant line branched from a downstream point of the inner condenser of the main refrigerant line based on a flow direction of the refrigerant and connected to the compressor, and a gas injection heat exchanger configured to perform heat exchange between the refrigerant flowing through the gas injection refrigerant line and the refrigerant flowing through the main refrigerant line.
US12240290B2	Heat pump system for vehicle A heat pump system for a vehicle includes a compressor; a four-way valve for transferring refrigerant to external or internal heat exchanger; the external heat exchanger for heat-exchanging between the external air and the refrigerant, the internal heat exchanger for heat-exchanging between the refrigerant and the air supplied to the interior of the vehicle, or for heat-exchanging between the refrigerant and the air supplied to the interior of the vehicle; an electric component cooling circuit which absorbs the heat from electric components in the vehicle, to emit same through electric component radiator, or which absorbs heat, and heat-exchanges with refrigerant/electric component coolant heat exchanger for heat-exchanging between the refrigerant and a coolant; a first expansion means for expanding the refrigerant; and a battery chiller which heat-exchanging between a battery and the refrigerant and transferring the refrigerant to the internal heat exchanger.
US12240286B2	Air spring control system, air spring system, vehicle including same, and method for same An air suspension control system is for a vehicle with a first and a second axle. The system has an auxiliary control unit connected to a main control unit via a data link. The auxiliary unit has a pressure sensor associated with the first axle for determining pressure measurements of the first axle as pressure sensor signals and an input for receiving height sensor signals. The input can be connected to a first height sensor on the first axle for receiving first height signals and to a second height sensor on the second axle for receiving second height signals. The auxiliary unit is adapted to transmit the first and/or second height sensor signals and/or the pressure sensor signals to the main unit. The main unit is adapted to carry out weighing for the first and/or second axle in dependence on the first and/or second height signals and/or the pressure signals.
US12240285B2	Sensory evaluation system, suspension device, and suspension control system A sensory evaluation system performs sensory evaluation on a plurality of sensory indexes corresponding to respective feelings of an occupant according to traveling of a moving body, and includes: a data adjustment unit that generates evaluation data to be used for the sensory evaluation based on information acquired according to the traveling of the moving body; an evaluation index determination unit that selects at least any one sensory index as an evaluation index from among the plurality of sensory indexes based on the information; an evaluation unit that calculates an evaluation value for the evaluation index from the evaluation data using an evaluation circuit corresponding to the evaluation index; and an aggregation unit that aggregates the evaluation value calculated by the evaluation unit.
US12240278B2	Tires and wheels comprising adjustable stiffening lines, and machines having same A tire has a carcass with a tread, a bead, a shoulder, and a sidewall. The bead, shoulder, and sidewall partially define a first internal cavity. At least one stiffening line for a pressurized fluid with a second cavity is within the carcass. The second cavity is aligned in an approximately transverse direction relative to the periphery of the tire. The second cavity is connectable to pressurized fluid supply system and can be inflated or deflated to adjust the stiffness of the tire. The stiffening lines may be inflated using a hydraulic fluid to increase the stiffness of the tire. Related wheels, vehicles, and methods are also disclosed.
US12240277B2	Polyurethane gauge wheel tire A disclosed example embodiment of a gauge wheel tire includes a first polyurethane sidewall portion, a second polyurethane sidewall portion, a polyurethane ground-engaging portion, and a polyurethane axial support portion. The first polyurethane sidewall portion is spaced apart from the second polyurethane sidewall portion, and the polyurethane ground-engaging portion extends from the first polyurethane sidewall portion to the second polyurethane sidewall portion and is adapted to contact a ground surface as the gauge wheel tire rotates about an axis of rotation. The polyurethane axial support portion extends from the first polyurethane sidewall portion to the second polyurethane sidewall portion, and is spaced apart from the polyurethane ground-engaging portion to form a gap that allows radial movement of the polyurethane ground-engaging portion relative to the polyurethane axial support portion.
US12240275B2	Flat free tire A self-sealing pneumatic tire having at least one cohesive sandwich radially inward of the pneumatic tire is provided. The at least cohesive sandwich may include a cohesive material under pressure, facilitating a recovery capacity upon being pierced by a sharp object, whereby the molecules of the cohesive material cohesively reattach, self-sealing any passageway or space created by the sharp object. The self-sealing pneumatic tire may also provide a loculated-diamond-section layer located radially inward of the outer cohesive sandwich, further supporting the self-sealing pneumatic tire. The external rubber tread are disposed along the circumference of the tire in some embodiments can be separate from the surface of the tire yet secured in place by attachments. Once fully utilized, this external rubber tread can be replaced by a new version without having to replace the entire tire.
US12240274B2	Tire A tire includes shoulder main grooves, circumferential narrow grooves disposed between the shoulder main grooves and each having a groove width of 0.5 mm to 3.0 mm, and five or more rows of land portions defined by the shoulder main grooves and the circumferential narrow grooves. A first land portion includes S-shaped sipes that extend through the first land portion in a width direction. A second land portion includes S-shaped sipes that extend through the second land portion in the width direction, and the second land portion is a rib including a continuous road contact surface in a tire circumferential direction when the tire comes into contact with the ground. Connection portions of the S-shaped sipes of the first and second land portions with respect to the circumferential narrow grooves are at identical positions in the tire circumferential direction.
US12240273B2	Pneumatic tire A pneumatic tire includes, on a tread surface, circumferential main grooves extending in the tread circumferential direction, rib-like land portions defined between circumferential main grooves adjacent in the tread width direction or by circumferential main grooves and tread edges, and resonators, arrayed circumferentially in the rib-like land portions, each including a narrowed neck and an air chamber. The narrowed neck is a widthwise sipe opening at one end to the circumferential main groove that defines the rib-like land portion, extending therefrom in the tread width direction, and terminating at another end within the rib-like land portion. The air chamber is a circumferential sipe connected to the other end of the widthwise sipe, extending in the tread circumferential direction, terminating at both ends within the rib-like land portion, and including a first widened portion, at the sipe bottom, with a larger sipe width than at the tread surface side.
US12240269B1	Load wheel with heat dissipating hub A load wheel for a vehicle is provided having a cylindrical hub with an axis, a first sidewall, a second sidewall, an outer surface, a central core extending coaxially within the hub, and a plurality of passageways extending in an axial direction between the first and second sidewall. A solid, non-pneumatic tire is bonded to the outer surface of the hub, and a set of bearing is mounted in the central core of the hub. The hub is characterized by a “heat factor” equal to the (hub mass×hub specific heat)/surface area exposed. The heat factor for a hub comprising passageways is compared to the heat factor for a solid hub to derive a heat factor ratio, which is used to select the exposed surface area of the hub and maintain the operating temperature of the wheel below the failure temperature.
US12240265B1	Erasable writable substrates and methods of manufacture A magnetic erasable writable material for large format applications is disclosed, and includes a cast polyvinylchloride film with a mount surface opposite an etched receiver surface. Also incorporated is a transparent polyester film that has a marking side with a first predetermined hardness and an opposite seal side, laminated to the receiver surface. The marking side includes a clear superstrate that has a second predetermined hardness and applied to the marking side of the polyester film to lower its surface energy. The receiver surface is treated to have a surface energy adjusted to enable improved adherence of printed and preformed graphic elements, which are encapsulated when laminated between the PET film and receiver surface. The superstrate includes a perfluoropolyether, a polyurethane, an acrylated polyurethane, and/or an acrylate resin to harden the material.
US12240260B2	Dye sublimation apparatus with a multi-zone independent heater control An illustrative dye sublimation apparatus may include a heating surface that may have multiple zones. Each zone may include a single individually controlled heater. A controller may control the heater to generate a range of heat and not merely turn the heater ON and OFF. Therefore, one or more controllers may individually regulate heat from corresponding heaters in the zones thereby maintaining a constant and nearly constant temperature throughout the bed of the dye sublimation apparatus in the heating surface. Furthermore, one or more controllers may maintain a first range of temperature during a first state of a dye sublimation process and a second range of temperature during a second stage of the dye sublimation process.
US12240258B2	Tape cassette The tape cassette includes a housing, a tape roll, a tape, an outlet, a first guide, first opening, second opening, a first rotation body, and a second rotation body. The first guide is configured to guide the tape that has been conveyed through a detection position toward the outlet. The first opening opens toward a first surface of the tape. The second opening opens toward a second surface of the tape. The first rotation body is disposed at a position adjacent to the first opening. The position adjacent to the first opening is an entrance to the detection position. The second rotation body is disposed further upstream than the first guide in a tape conveyance direction. The second rotation body is disposed at a position adjacent to the second opening. The position adjacent to the second opening is an exit from the detection position.
US12240254B2	Automatic tuning compensation mechanism A printing system is disclosed. The printing system includes at least one physical memory device to store compensation logic and one or more processors coupled with the at least one physical memory device to execute the compensation logic to receive measurement data corresponding to a print medium printed with a plurality of pel forming elements in adjacent printheads and a plurality of tint levels, wherein the plurality of pel forming elements comprise gap adjacent pel forming elements that print with applied compensation transfer functions and non-gap adjacent pel forming elements, associate measurement data values with the gap adjacent pel forming elements, the applied compensation transfer functions and the plurality of tint levels and determine optimal compensation by selecting the compensation transfer functions that have corresponding measurement data values closest to compensation target values for each of the plurality of tint levels.
US12240249B2	Board, liquid accommodation container, and printing system In a board that includes a plurality of contact portions that are arranged to contact corresponding apparatus-side terminals when the board is mounted in a printing apparatus, some contact portions are disposed in a first region, and the remaining contact portions are disposed in a second region. The some contact portions include a first contact portion, a second contact portion, a third contact portion, and a fourth contact portion. The remaining contact portions include a fifth contact portion. The some contact portions are arranged in a first pattern in the first region and the remaining contact portions are arranged in a second pattern in the second region, and the first pattern is asymmetrical to the second pattern with respect to a first virtual line.
US12240247B2	Device, board, liquid accommodation container, and printing system A device outputs a first low voltage to a first terminal at a first timing in a period in which a voltage input to a second terminal is a high voltage. After outputting the first low voltage, the device outputs a second high voltage to the first terminal at a second timing in a period in which the voltage input to the second terminal is a low voltage. After outputting the second high voltage, the device outputs a second low voltage to the first terminal at a third timing in a period in which the voltage input to the second terminal is a high voltage.
US12240246B2	Liquid holding member, cap, and cartridge A liquid holding member includes a bottom surface, and a plurality of convex portions projecting from the bottom surface. Each of the convex portions includes a plurality of surfaces. The convex portions are molded integrally with the bottom surface.
US12240245B2	Logic circuitry In an example, a logic circuit comprising a communications interface including a data contact to communicate via a communications bus, an enablement contact, separate from the communication interface, to receive an input to enable the logic circuit, and at least one memory register, comprising at least one reconfigurable address register. The logic circuit may be configured, such that, when enabled, it responds to communications sent via the communication bus which are addressed to the address held in a reconfigurable address register.
US12240244B2	Cartridge and printing system A cartridge includes a liquid container and an adaptor. The liquid container has a liquid storage containing a liquid to be supplied to a printing apparatus, a liquid supply section configured to supply the liquid contained in the liquid storage to a liquid introduction section, and an adaptor mounting section. The adaptor is mounted on the adaptor mounting section and has a terminal placement section in which a cartridge-side terminal electrically connected to an apparatus-side terminal is disposed and an insertion aperture through which the liquid introduction section passes. The adaptor mounting section is provided with a mounting mechanism for mounting the adaptor, which has a predetermined constant shape.
US12240240B2	Liquid ejection head A liquid ejection head includes a plate including a nozzle for ejecting a liquid, a substrate, an actuator including a pressure chamber. The actuator includes an upper surface and a side surface connecting the upper surface to the substrate. The side surface is at an angle θ between 45 and 90 degrees. The head includes an electrode connected to the chamber. The electrode includes a first wiring on the side surface and a second wiring on the substrate within a first region thereof. The first region has a length A from a position of a line along which the upper and side surfaces meet, and the value of length A is B/tan θ′, where B is a distance between the upper surface and the substrate and θ′ is (θ−45)×2.
US12240239B2	Microfluidic passage with protective layer A microfluidic die may include a microfluidic passage and a protective layer provided adjacent to internal surfaces of the microfluidic passage. The protective layer may include a protective nano-crystalline material and a protective amorphous matrix encapsulating the protective nano-crystalline material.
US12240236B2	Head, head module, liquid discharge apparatus, printer, module, and apparatus A head includes: an attachment attached to a holder with a screw, the attachment having a through hole to which the screw is inserted, and the through hole having: a female screw having a valley and a crest; and a first concave having a diameter larger than a diameter of the valley of the female screw, the first concave opening toward the holder.
US12240225B2	Printing apparatus A drying unit includes a first contact heating unit provided inside a housing, and a second contact heating unit provided downstream in a transport direction from the first contact heating unit inside the housing. The first contact heating unit includes a first contact heating surface configured to come into contact with a back surface of a medium after printing. The second contact heating unit includes a second contact heating surface configured to come into contact with the back surface of the medium after printing. The first contact heating surface is curved to have a shape protruding in a direction opposite to the second contact heating surface, and the second contact heating surface is curved to have a shape protruding in a direction opposite to the first contact heating surface. The first contact heating surface has a radius of curvature larger than that of the second contact heating surface.
US12240223B2	Printer The technique provided enables, when first ink is precured and second ink is ejected thereon, ensuring sufficient adhesion of the second ink via a primer. A printer includes a transport mechanism, a primer ejection head, a second light irradiator, a white-ink ejection head, a color-ink ejection head, and a controller. The controller controls the amount of primer ejected to a unit region of a continuous base material by the primer ejection head, the amount of white ink ejected thereto by the white-ink ejection head, and the amount of color ink ejected thereto by the color-ink ejection head. The controller determines a first primer amount based on the amount of white ink and determines a second primer amount based on the amount of color ink. The controller then determines an ultimate primer amount based on the sum of the first primer amount and the second primer amount.
US12240222B2	Printing system A printing system includes a coating device, a printing device, and a controller. The coating device applies a processing liquid to a base material by bringing a coating roller with the processing liquid adhering thereto into contact with the transported base material. The printing device performs printing on a surface of the base material to which the processing liquid has been applied. The controller includes a contact-start-position identifier, an inappropriate-printing-area setter, and a print controller. The contact-start-position identifier identifies a contact start position of the base material in which the coating roller and the base material start to come in contact with each other. The inappropriate-printing-area setter sets, as the inappropriate printing area, an area of the base material that has a predetermined length in a transport direction from the contact start position. The print controller stops the printing device from performing printing on the inappropriate printing area.
US12240221B2	System and method to reduce the visibility of gloss differentials on printed sheets Printing system and method for reducing the visibility of gloss differentials having at least one computer-supported inline imaging unit assembly designed to measure specular light reflecting gloss differentials of printed ink. At least one smoothing roller assembly is operationally connected to at least one sheet transport assembly or a smoothing transport subassembly of the sheet transport assembly of the printing system. A smoothing roller assembly is designed to roll at least partly the length and width of at least one printed side of at least one printed sheet disposed along the transport subassembly, pressure generated by the smoothing roller assembly configured to reduce detected gloss differentials from printed ink. At least the outer surface of the at least one smoothing roller assembly is substantially at least one or more of metal and polyurethane.
US12240219B2	Platen and release fluid control system for stencil creation A direct to mesh (DtM) screen printer for creating a screen stencil is provided. The DtM screen printer includes a fixture to hold a frame. which holds a pre-stretched mesh in place during application of a jettable emulsion. a platen having a cavity and an array of holes in a top surface of the platen, a non-woven fabric placed on the top surface of the platen and saturated with a release fluid located against one side of the pre-stretched mesh, and a printer carriage supporting a print head for printing the jettable emulsion on a side of the pre-stretched mesh opposite the non-woven fabric.
US12240215B2	Hybrid reinforcement structure A structural reinforcement for insertion into a cavity of a vehicle structure including a base reinforcing portion, an expandable material and a localized reinforcement is disclosed. The localized reinforcement is placed within the structural reinforcement at a location of anticipated increased deformation during vehicle impact in an effort to reduce deformation and control the load distribution post-impact.
US12240209B2	Liquid storage bag A liquid storage bag includes a bag configured to store a liquid and a feeder that feeds the liquid in the bag to an external component. The bag is formed of a film. The film includes a first base layer, a second base layer, and a first black layer located between the first base layer and the second base layer. The first black layer is formed of a black colorant filling a layer surface of the second base layer.
US12240205B2	Composite pane comprising a sun shading coating A composite pane includes an outer pane having an exterior-side surface and an interior-side surface, an inner pane having an exterior-side surface and an interior-side surface, and a thermoplastic intermediate layer joining the interior-side surface of the outer pane to the exterior-side surface of the inner pane. The composite pane has a sun shading coating between the outer and inner panes. the sun shading coating includes, starting from the outer pane toward the inner pane, a layer sequence first dielectric module M1, first silver layer Ag1, second dielectric module M2, second silver layer Ag2, third dielectric module M3, third silver layer Ag3, fourth dielectric module M4, wherein the silver layers have, relative to one another, a geometrical layer thickness of 0.4
US12240202B2	Laminated glass retention system Embodiments herein relate to a system and method for retaining an insulated glass subassembly including a laminated layer of glass within a frame of a fenestration unit providing protection against wind borne debris. A fenestration unit can include a frame member defining a channel with a lower end and an attachment surface thereon along with a glass subassembly including a proximal end received and seated within the channel and an outside facing surface of the exterior pane proximate the lower end of the channel. A retention member can engage the interior laminate pane, and a glazing material can be on the attachment surface at the lower end of the channel. The outside facing surface of the glass subassembly can be attached to the channel of the frame member with the glazing material. In various embodiments, methods of making a retention member are included herein. Other embodiments are also included herein.
US12240199B2	Welded member To obtain a welded member using a steel sheet less expensive than a pure Ni sheet as a raw material and excellent in corrosion resistance. A welded member according to the present invention is made by connecting a Ni plated steel sheet having a Ni plating layer and a Fe—Ni diffusion alloy layer and another steel sheet via a welded part, wherein: a Ni concentration is 70 mass % or more and a Fe concentration is 30 mass % or less in a surface layer of each of a toe, a toe near area, and the welded part; and a thickness of the Fe—Ni diffusion alloy layer is 0.5 to 1.5 μm and a total thickness of the Ni plating layer and the Fe—Ni diffusion alloy layer is 2.7 to 14.0 μm at a non-welded part, and a total concentration of S and C in the Ni plating layer at the non-welded part is less than 20 ppm.
US12240195B2	Wind turbine blade shear webs According to the present invention there is provided a mould for making a wind turbine blade shear web. The shear web comprises a longitudinally-extending web panel and a mounting flange extending along a longitudinal edge of the web panel and transverse to the web panel. The mounting flange comprises a first portion extending on a first side of the web panel and a second portion extending on a second side of the web panel. The mould comprises a longitudinally-extending main surface shaped to form the web panel, the main surface having a longitudinal edge. The mould further comprises a side surface arranged transverse to the main surface and extending downwards from the longitudinal edge of the main surface. The mould further comprises a base surface arranged transverse to the main surface and spaced from the side surface, the base surface having a first portion extending below the main surface to a first end of the base surface and a second portion extending above the main surface to a second end of the base surface. The first portion of the base surface is spaced from the side surface to define a mould cavity between the side surface and the first portion of the base surface, the mould cavity being configured to form the first portion of the mounting flange. The mould further comprises a datum-forming surface extending transversely from the second end of the base surface and defining a longitudinal edge at an intersection of the second portion of the base surface and the datum-forming surface. The second portion of the base surface and the datum-forming surface are configured to form the second portion of the mounting flange, and the datum-forming surface is configured to define a longitudinal edge of the second portion of the mounting flange.
US12240193B2	Method for producing a tire provided with a radiofrequency communications module A method for manufacturing a tire (1) equipped with a communication module (20) consists in successively, and in the order required by the architecture of said tire, laying rubber products, notably profiled elements (50) and reinforcing elements on a given support in order to yield a green tire (1), then in vulcanizing the green tire to yield a tire (1), wherein, prior to laying one of the rubber profiled elements (50) on the green tire, a slot (52) is created starting from a surface of the rubber profiled element (50) and the communication module (20) is introduced into the slot (52).
US12240187B2	Spacer for use in precision bonding applications that provides enhanced shear strength A spacer-locator with integrated locator pins and spacer tabs for use in joining applications. The spacer-locator provides consistent and accurate spacing between mating surfaces and the locator pins provide enhanced location control of the joining components while providing a mechanical advantage to the shear strength at the joint. Also, a spacer-locator for joining at least two objects along mating surfaces, the spacer-locator constraining at least two degrees of freedom for the objects to be joined.
US12240177B2	Printing method for additive manufacturing, including in-situ powder regeneration by removing portions of deposited powder A method and system for 3D printing for creating at least two discrete sections of powder on a substrate, segmenting the substrate to isolate the at least two discrete sections of powder, compacting the powder on a segment of the substrate, removing loose/non-compacted powder from the segment of the substrate, create a printed/processed layer by performing one or more of a printing process or a processing operation on the segment of substrate, and transferring the printed/processed layers from the segment of substrate to a build platform.
US12240175B2	Docking arrangement for an additive manufacturing process A Docking Arrangement for an Additive Manufacturing Process An operating handle (50) for controlling the operational state of a valve arrangement (26) associated with a container (12) to control dispensing of material from the container (12) to a component of an additive manufacturing process. The operating handle (50) includes a rotatable shaft 56 which is coupled to the valve arrangement (26) and is rotatable between a plurality of angular positions corresponding one or more operational states of the valve arrangement (26). A lever (52) is operatively coupled to the shaft (56) and is configured to cause rotation of the shaft (56) between the plurality of angular positions upon rotation of the lever (52). The handle (50) is also rotatable under the operation of an actuator (40) provided as part of a docking arrangement (10) associated with the component.
US12240174B2	Continuous 3D printing A method of 3D printing, a 3D printing system, and a vertical conveyor are disclosed herein. The 3D printing system comprises a vertical conveyor having a plurality of folding build plates; a plurality of biasing devices, a biasing device being configured to rotate a folding build plate from a folded position to a substantially horizontal position when the folding build plate enters a printing chamber position, and a 3D print head inside the print chamber adapted to 3D print an object on the folding build plate in the substantially horizontal position.
US12240173B2	Cylindrical coordinate 3D printer and methods of operation thereof Disclosed are cylindrical-coordinate 3D printers and methods of 3D printing. In one embodiment, the cylindrical-coordinate 3D printer can comprise a printbed, a rotatable printbed support assembly, a vertically translatable base plate supporting the printbed support assembly, four rail segments aligned radially with the printbed support assembly, and four gantry carriers configured to carry or support four printheads. The gantry carriers can be moveable along the rail segments. The four gantry carriers can be moved simultaneously.
US12240165B2	Metering device, device and method for additively producing a three-dimensional object A metering device serves as an equipping or retrofitting kit for a device for producing a three-dimensional object by means of solidifying, layer by layer, a building material in powder form at those positions that correspond to the cross-section of the object to be produced in the respective layer. The metering device has a metering element, which metering element is rotatable about an axis, preferably an axis of its own, particularly preferably about an, in particular its own, longitudinal axis and which is suitable for dispensing the building material in powder form in a metered manner. The metering element is designed to dispense locally different amounts of powder along the direction of the axis.
US12240158B2	Multi-joint robot capable of motion control Provided is a multi-joint robot which is capable of performing motion control and includes a part for easily setting a moving path, an angle, and the like of a take-out device in a process of taking out an injection-molded object. To this end, the present disclosure includes a molding part configured to mold an object, a multi-joint robot configured to move close to the molding part and take out the object, a first controller connected to the above work components and configured to control driving of the work components, a marker connected to the first controller and provided on each of joints of the multi-joint robot, and a camera part configured to photograph movement of the marker, and transmit movement information of the multi-joint robot according to the movement of the marker to the first controller, and an overrun detector is provided on at least one of the joints of the multi-joint robot to detect an overrun operation exceeding an operation range of a joint movement and transmit a warning signal about the overrun operation to the first controller. According to the present disclosure, even a low-skilled worker can easily set access and work of a worker at an injection molding site without performing coding, thus reducing a difficulty level of work and maximizing process efficiency, control whether to perform injection according to whether a door is open or not, thereby securing safety, and control quality and a take-out environment using environmental information received by the molding part.
US12240157B2	Integrally molded body and method of manufacturing same An integrally molded body has a rectangular planar structure in which an inner resin material containing a thermoplastic resin is interposed between a plate material having a design surface and an outer resin material containing a thermoplastic resin, the planar structure having a first joint in which at least a partial region of the outer-peripheral-side surface part and/or the outer peripheral edge part of the plate is joined with the inner resin material, and a second joint in which at least a partial region of the outer-peripheral-side surface part and/or the outer peripheral edge part of the inner resin material is joined with the outer resin material.
US12240154B2	Methods and systems for making fibrillar adhesion structures A method, system, and apparatus for a fibrillar adhesion device comprises forming a stem mold, generating an array of at least one stems using the stem mold, forming a cap mold, generating an array of at least one caps using the cap mold, adhering the array of at least one stems to the array of at least one caps, and removing the cap mold wherein the resulting system comprise an array of at least one fibrillar adhesive structures.
US12240147B2	Concrete drum control, property prediction, and monitoring systems and methods A drum control system includes one or more processing circuits having programed instructions to control a drum assembly to rotate a drum at a first, unmixed speed to mix drum contents received by the drum where the drum contents including ingredients of a concrete mixture, acquire drum contents data indicative of a property of the drum contents from a mixture sensor and monitor the property of the drum contents as the drum rotates, acquire a target property for the drum contents upon delivery, determine a second, mixed speed based at least partially on the target property, and control the drum assembly to rotate the drum at the second, mixed speed in response to determining that the property of the drum contents indicates that the ingredients have been sufficiently mixed.
US12240146B2	Nozzle for dispensing concrete, mortar or the like The invention relates to a nozzle (10) for dispensing concrete, mortar or the like, comprising a housing (12) and a mixing chamber (14) which is arranged therein and is delimited by a circumferential wall (16) and extends along a longitudinal axis (L) at least between a supply opening (19) and an outlet opening (20); an actively driveable mixing device, which is arranged in the mixing chamber (14); and an exit opening (32), which is directly or indirectly flow-connected to the outlet opening (20) of the mixing chamber (14). At least one cavity (44; 44a, 44b), which extends axially and in the circumferential direction, is arranged around the circumferential wall (16) of the mixing chamber (14) and is in contact with the circumferential wall (16) and at least substantially surrounds the mixing chamber (14) in the circumferential direction. The circumferential wall (16) of the mixing chamber (14) consists of elastic material, which is adapted to deform dynamically into the at least one cavity (44; 44a, 44b) during operation of the nozzle. In this way, the formation of deposits on the circumferential wall (16) of the mixing chamber (14) is avoided.
US12240141B2	Sawing facility and method for sawing a sawing material A sawing facility includes a rail guide, a saw arranged on the rail guide, a first carriage arranged on one side of the saw along the rail guide, and a second carriage arranged on the other side of the saw along the rail guide. The first carriage includes a first saw log support and a first carriage drive that can move the first carriage together with a first saw log on the rail guide and past the saw to saw the first saw log. The second carriage includes a second saw log support and a second carriage drive that can move the second carriage together with the second saw log on the rail guide and past the saw to saw the second saw log. The second saw log is loaded onto the second saw log support while the first saw log is sawed using the first carriage.
US12240138B2	Hand tool with replaceable workpiece head A hand tool with a replaceable workpiece head includes a handle and a workpiece head. A rear end of the workpiece head is provided with an insertion block. A front end surface of the handle is provided with an insertion hole. The insertion block of the workpiece head is inserted into the insertion hole. A side wall of the handle is provided with a receiving slot which is communicated with the insertion hole. A rear end of the insertion block is provided with a locking part. The receiving slot is provided with a movable locking member and a pushing mechanism. The pushing mechanism is capable of pushing the movable locking member such that the movable locking member and the locking part are engaged with each other.
US12240132B2	Reducing sound production in a hair-cutting unit comprising an external cutting member and a rotatable internal cutting member In an external cutting member (10) which is configured to be used in a hair-cutting unit in combination with a rotatable internal cutting member, a base (11) includes at least one hair-cutting track (21) which is provided with a plurality of hair-entry openings, and an annular base portion (31) located between a central portion (17) of the base (11) and an innermost one of the at least one hair-cutting track (21). The annular base portion (31) is provided with a profiled section which is located between a straight inner section (32) and a straight outer section (33) of the annular base portion (31), which is annular about a central axis (16) of the external cutting member (10), and which is shaped according to a predefined profile, seen in a cross-section of the external cutting member (10) comprising the central axis (16).
US12240124B2	Moving along a predetermined path with a robot A method for moving along a predetermined path with a robot in an at least a partially automated manner includes determining a deployment position on a current path section of the predetermined path for which a distance parameter satisfies a predetermined condition, and moving to the deployment position with the robot. In one aspect, the robot may be moved to the deployment position if a deployment condition is satisfied. The distance parameter may be determined on the basis of a distance of a current position of the robot relative to the current path section. The predetermined condition may be that the distance parameter has a value that is less than or equal to the values of the distance parameter of all positions in a partial area of the current path section, which is in particular complementary to the deployment position.
US12240123B2	Robotic kitting machine A robotic kitting machine is disclosed. In various embodiments, a robotic arm is used to move an item to a location in proximity to a slot into which the item is to be inserted. Force information generated by a force sensor is received via a communication interface. The force sensor information is used to align a structure comprising the item with a corresponding cavity comprising the slot, and the item is inserted into the slot.
US12240122B2	Palletizing boxes A method for palletizing by a robot includes positioning an object at an initial position adjacent to a target object location, tilting the object at an angle relative to a ground plane, shifting the object in a first direction from the initial position toward a first alignment position, shifting the object in a second direction from the first alignment position toward a second alignment position, and releasing the object from the robot to pivot the object toward the target object location.
US12240121B2	Robots and methods for utilizing idle processing resources The present disclosure relates to utilizing idle processing resources of a robot to reduce future burden on such processing resources. In particular, idle processing resources are utilized to identify future scenarios, and generate reactions to such future scenarios. The generated reactions are stored, and quickly retrieved as needed if corresponding identified future scenarios occur.
US12240118B2	Force amplification mobile robotic system (exobot) The present invention proposes a mobile robotic system capable of carrying out the movement, manipulation and precise installation of industrial loads (pipes, plates, equipment, parts, materials, etc.), using a single operator for that and presenting ease of use. The invention is basically composed of an anthropomorphic-type industrial robot (3) and a crawler mobile platform (11). The load capacity of the invention is limited by the maximum load capacity of the industrial robot employed. The precise positioning step has a special force amplification system (external exoskeleton) capable of moving a load fixed on the industrial robot wrist (position and orientation) with the force actions of an operator, directly on the robot wrist, or by means of a security extension. The robotic system can be controlled by radio control, capable of allowing both the control of the robot and the movement of the platform.The proposed system of this invention comprises a mobile platform for all types of terrain, an industrial robotic arm, an effector for handling pipes, an effector to pick up metal plates, the respective supports of effectors in a quick tool change system, a diesel electric generator, an industrial radio control, safety sensors and a video monitor for two cameras positioned on the robot structure.
US12240104B2	Wrist cover, robot, and wrist cover set A wrist cover covers a wrist of a robot. The wrist includes a first wrist element, a second wrist element, and a third wrist element coupled in series and rotatable with respect to one another. The wrist cover includes: a rotating seal member that is fixed to the second wrist element, thereby sealing a ring-shaped gap between the second wrist element and the third wrist element while allowing relative rotation between the second wrist element and the third wrist element; and a flexible bag-shaped cover body that has a first opening arranged so that the first wrist element is passed therethrough, and a second opening arranged so that the third wrist element is passed therethrough. The cover body and the rotating seal member are attached with a space between a peripheral edge of the second opening and the rotating seal member being sealed over the entire periphery thereof.
US12240100B2	Controlled compliant gripping and manipulating system for a robot A compliant end effector includes a robot mounting bracket and a component support member. The component support member includes a side surface and a top surface. A component clamping system includes a first clamp member operable to move toward the side surface of the component support member and a second clamp member operable to move toward the top surface of the component support member. A controller is operatively connected to the clamping system. The controller is configured to engage the first and second clamp members as the component gripping and manipulating system is in a set position and release the first clamp member and the second clamp member allowing a portion of a component held by the component clamping system to move with one or more degrees of freedom when the component gripping and manipulating system is moving to the set position.
US12240096B2	Portable socket holder for sockets or bits connectable to a power tool The present disclosure relates to a portable socket holder for sockets or bits connectable to a power tool. The portable socket holder comprising socket compartments for different types of sockets or bits. The portable socket holder further comprising visually indication means arranged to visually indicate a socket compartment. Further the portable socket holder comprising a processor and a memory containing instructions executable by the processor, wherein the portable socket holder is operative to visually indicate by means of the visually indication means a socket compartment. The portable socket holder further comprising tightening joint element compartments for different types of tightening joint elements. The portable socket holder further comprising visually indication means arranged to visually indicate a tightening joint compartment. The portable socket holder further arranged to visually indicate based on which socket compartment that is visually indicated from which tightening joint element compartment a tightening joint element should be removed.
US12240093B2	Tool system, tool management method, and program A tool system includes a portable tool, an image capturing unit, and a control unit. The tool includes a driving unit to be activated with power supplied from a power source. The image capturing unit is provided for the tool and generates a captured image. The control unit controls the tool based on the captured image. The control unit has a work support capability. The work support capability is the capability of placing a restriction on operation of the tool when a work target identified based on the captured image does not conform to a working instruction defined by a working procedure. The control unit suspends, when finding a lifting condition satisfied while performing work-support-enabled operation, the work-support-enabled operation and thereby lifts the restriction on the operation of the tool.
US12240088B2	Compressed air nail gun with a safety device The invention relates to a pneumatic nailer having a working piston and a common actuation that is configured to trigger a drive-in process which has a control volume and which is designed to automatically undertake a safety measure when a pressure threshold in the control volume is exceeded or not met. The control volume is ventilated or vented via a throttle such that a delay time, after the expiration of which the pressure threshold is exceeded or not met, is specified by a volume of the control volume and an opening cross-section of the throttle. The control volume has a volume in the range from 0.5 ml to 20 ml and the throttle is a bore having a diameter in the range from 30 μm to 200 μm.
US12240087B2	Handheld tool A handheld tool includes a nose portion having an injection passage for a fastener, a magazine accommodating the fastener and located in a direction intersecting with the injection passage, a magazine cap portion opening and closing the magazine by a tip portion rotating in a direction separating from and approaching the magazine with a base end portion as a fulcrum, and a door portion rotatably coupled to the tip portion via a coupling shaft. The nose portion includes an engaging portion engageable with the door portion. The door portion is configured to, in a state where the magazine cap portion is opened, bent toward the magazine with the coupling shaft as a fulcrum, and in a state where the magazine cap portion is closed, extend linearly and engage with the engaging portion.
US12240082B2	Hydraulic torque wrench and control system for a hydraulic torque wrench A hydraulic torque wrench comprises a ratchet link, a power head, and a signal carrying connector for connection to a controller. The ratchet link includes a housing and a drive plate mounted for rotation about an axis within the housing, the drive plate mounting one part of a first part of a ratchet drive. A socket is mounted for rotation within the housing, the socket providing a second part of the ratchet drive. During rotation of the drive plate in one direction the first and second part of the ratchet drive engage each other to cause rotation of the socket with the drive plate and during rotation of the drive plate in a second direction one of the first and second parts of the ratchet drive rides over the other such that the socket remains stationary while the drive plate rotates. The power head includes a piston and cylinder and hydraulic connections adapted for connection to a source of pressurised hydraulic fluid. The torque wrench mounts a proximity sensor connected to the signal carrying connector and configured to detect maximum extension of the piston. When maximum extension of the piston is detected the proximity sensor emits an electrical signal.
US12240081B2	Rapid adjustable wrench A rapid adjustable wrench includes a body, a movable jaw, and an engaging device. The body has a fixed jaw, a sliding groove, and a containing recess. The movable jaw includes a sliding portion movably arranged in the sliding groove and a first toothed portion adjacent to the sliding portion. The engaging device includes an engaging member and a toggle switch. The engaging member is arranged in the containing recess and has a second toothed portion selectively engaged with the first toothed portion. One end of the toggle switch is connected to the engaging member. The toggle switch is able to drive the engaging member to move between an engaging position and a releasing position.
US12240071B2	Five-axis vertical processing system for automatic loading and unloading The present invention discloses a five-axis vertical machining system with automatic loading and unloading, including a feeding mechanism, a loading mechanism, and a numerical control machine tool. The feeding mechanism is arranged in front of a ram assembly, and the feeding mechanism drives a raw material to move along an X axis and/or a Y axis of the numerical control machine tool; the loading mechanism is fixed on the ram assembly; and the loading mechanism moves along a Z axis of the numerical control machine tool to drive the raw material onto a cradle assembly of the numerical control machine tool. The present invention realizes an automatic loading and unloading function by setting a feeding mechanism capable of automatic feeding and a loading mechanism with automatic loading to cooperate with each other, thereby improving the working efficiency and saving manpower.
US12240070B2	Gearbox case with wear sleeve A gearbox may include a gearbox case with a wear sleeve disposed within a shaft bore, and a gear assembly mounted on a shaft and disposed within the shaft bore. The gear assembly may include a bearing that engages the wear sleeve. A method of repairing a gearbox case may include uncoupling a top piece and a bottom piece of the gearbox case, forming an oversize bore in a shaft bore of the gearbox case to remove a damaged area, and installing a wear sleeve in the oversize bore.
US12240068B2	Air cooled condenser and related methods A vertical bundle air-cooled heat exchanger, a finned tube assembly for an air cooled condenser and method for forming the same, and a system for removing thermal energy generated by radioactive materials. In one aspect, an air cooled condenser sized for industrial and commercial application includes an inlet steam distribution header for conveying steam, a condensate outlet header for conveying condensate, an array of tube bundles each having a plurality of finned tube assemblies having a bare steel tube with an exposed outer surface and a set of aluminum fins brazed directly onto the tube by a brazing filler metal. The steel tubes may be spaced apart by the aluminum fins and have an inlet end fluidly coupled to the inlet steam distribution header and an outlet end fluidly coupled to the outlet header. A forced draft fan may be arranged to blow air through the tube bundles.
US12240066B2	Weld joints involving dissimilar metals and methods for forming same A method of joining a steel first member to a stainless steel second member includes buttering a first joint surface on the first member, the buttering including: preheating the first joint surface; welding a border layer of weld material to the first joint surface; and heat treating the border layer and the first joint surface after welding the border layer. A weld is formed between the first and second members after heat treating the border layer and the first joint surface. The border layer and a second joint surface on the second member are preheated; and a body of weld material is added between the border layer and the second joint surface.
US12240063B2	Welding power supplies, wire feeders, and systems to compensate a weld voltage via communications over a weld circuit Methods and apparatus to communicate via a weld cable are disclosed. An example weld circuit communications device includes a receiver circuit, a processor, and a local communications adapter. The receiver circuit to receive a communication via a weld circuit while current is flowing through the weld circuit or after the current has stopped flowing through the weld circuit, the communication including weld voltage feedback information measured at a device remote from a power supply and remote from the weld circuit communications device while the current is flowing through the weld circuit. The processor generates power supply control information based on the weld voltage feedback information. The local communications adapter transmits the power supply control information to control welding-type power output by a power converter to regulate a weld voltage to a weld voltage setpoint.
US12240061B2	Flux resin composition, electronic component, method for manufacturing the electronic component, mounting structure, and method for manufacturing the mounting structure A flux resin composition includes an epoxy resin, an imidazole compound, a thixo agent, and an activator. The epoxy resin includes at least one resin selected from the group consisting of naphthalene epoxy resins, biphenyl aralkyl epoxy resins, trisphenol methane epoxy resins, biphenyl epoxy resins, and dicyclopentadiene epoxy resins. The content of the at least one resin is equal to or greater than 20% by weight with respect to a total weight of the epoxy resin.
US12240060B2	SnIn solder alloys Some implementations of the disclosure are directed to low melting temperature (e.g., liquidus temperature below 210° C.) SnIn solder alloys. A SnIn solder alloy may consist of: 8 to 20 wt % In; greater than 0 wt % to 4 wt % Ag; optionally, one or more of greater than 0 wt % to 5 wt % Sb, greater than 0 wt % to 3 wt % Cu, greater than 0 wt % to 2.5 wt % Zn, greater than 0 wt % to 1.5 wt % Ni, greater than 0 wt % to 1.5 wt % Co, greater than 0 wt % to 1.5 wt % Ge, greater than 0 wt % to 1.5 wt % P, and greater than 0 wt % to 1.5 wt % Mn; and a remainder of Sn.
US12240057B2	Method of laser cutting steel A method for laser cutting a steel alloy sheet/plate having a composition including, in wt. %: C: 0.0-0.29; Mn: 0.50-1.35; P: 0.04 max; S: 0.05 max; Si: 0.40 max; Cr: 0.5-0.75, and the remainder being iron and impurities, the steel alloy is free from intentional additions of Cu and Ni and containing less than 0.05% of total cumulated amounts of Cu and Ni.
US12240056B2	Ultrashort pulse laser butt welding The present disclosure provides methods, devices, and systems for the butt welding of two, e.g., planar, workpieces composed of glass, e.g., quartz glass, by a pulsed laser beam, e.g., an ultrashort pulse (“USP”) laser beam, which is directed into the workpiece material parallel to the joining surface of the two workpieces and which is focused into the workpiece material in the region of the joining surface to locally melt the two workpieces in the region of their joining surface, wherein the laser focus of the laser beam focused into the workpiece material is moved in or counter to the beam direction of the laser beam to produce in the region of the joining surface a weld seam extending along the beam direction.
US12240055B2	Optical zoom in additive manufacturing Optics assemblies and their methods of use in additive manufacturing systems are described. In some embodiments, an additive manufacturing system may include a build surface, a plurality of laser energy sources configured to produce a plurality of laser spots on the build surface, and an optics assembly configured to independently control a size of each of the plurality of laser spots and a spacing between the plurality of laser spots on the build surface. The optics assembly may include a plurality of lens arrays, where the plurality of lens arrays is configured to adjust a size of each of the plurality of laser spots on the build surface, and at least one lens. The at least one lens may also be configured to adjust a spacing between the plurality of laser spots on the build surface.
US12240053B2	Friction welding of cladded cemented or sintered carbides to a structural element A method for bonding a cemented (or sintered) carbide element to a structural component is provided comprising cladding at least one surface of the cemented (or sintered) carbide element with a metal alloy using diffusion bonding or brazing and friction welding a cladded surface of the cemented (or sintered) carbide element to the structural component.
US12240051B2	Ultrasonic resistance welding process and apparatus An ultrasonic resistance welding apparatus 10 contains a resistance spot welding apparatus 15, a first electrode 16 and a vibrable second electrode 18, the vibrable second electrode 18 in operable communication with an ultrasonic transducer 12, whereby the ultrasonic transducer 12 selectively imparts vibratory energy to the vibrable second electrode 18 based on signals from a controller 32. The vibrable second electrode 18 may be tuned or designed to resonate within 2.5% of an operating frequency of the ultrasonic transducer 12. During operation of the welding apparatus 10, a tip 19 of the second vibrable electrode 18 may be positioned at an anti-nodal point 38 of the vibratory energy and the vibrable second electrode 18 may be attached to the resistance spot welding apparatus 15 at a nodal plane 36 of the vibratory energy. A process for employing the apparatus 10 is also presented.
US12240049B2	Reamer The invention relates to a reamer (3), having a main body (5) and at least one cutting tip (1) arranged on the main body (5), the cutting tip (1) having a reamer section (7), the cutting tip (1) having, at a distance (A) from the reamer section (7), a roughening section (9) having at least one roughening blade (11), the at least one roughening blade (11) protruding beyond the reamer section (7) by a particular projection (D).
US12240042B2	System and method for inspecting components fabricated using a powder metallurgy process A method for nondestructive testing includes steps of: (1) forming a first inspection standard using a metal injection molding process; (2) forming a second inspection standard using the metal injection molding process; and (3) creating a reference library that includes the first inspection standard and the second inspection standard. The first inspection standard includes first voids that are induced by a first set of conditions of a sintering operation and a hot isostatic pressing operation of the metal injection molding process. The second inspection standard includes second voids that are induced by a second set of the conditions of the sintering operation and the hot isostatic pressing operation. At least one of the conditions in the second set of the conditions is different than at least one of the conditions of the first set of the conditions. The first voids and the second voids are different.
US12240038B2	Method of operating an apparatus for producing a three-dimensional work piece and apparatus for producing a three-dimensional work piece A method of operating an apparatus (10) for producing a three-dimensional work piece (18) by irradiating layers of a raw material powder with electromagnetic or particle radiation comprises the steps of a) applying a layer of raw material powder onto a carrier (12); b) selectively irradiating the layer of raw material powder with electromagnetic or particle radiation in accordance with a geometry of a corresponding layer of the work piece (18) to be produced; and c) repeating steps a) and b) until the work piece (18) has reached the desired shape and size. For at least a portion of at least some of the layers, a scanning time (ts) from the beginning of the exposure of a respective raw material powder layer portion to electromagnetic or particle radiation until the beginning of the exposure of a new raw material powder layer applied on top of said layer portion to electromagnetic or particle radiation is controlled so as to not fall below a specific minimum value which is individually set for said layer portion in dependence on a layer portion specific quality parameter. layer portion specific quality parameter.
US12240037B2	Installation for additive manufacturing by SLM or SLS An AM installation utilising SLM or SLS a chamber of a housing with a protective atmosphere, a support structure in the chamber defines an upper horizontal surface on which a laser source is operable for focusing onto predetermined regions of a build area of the plane of the horizontal surface. The laser beam source is operable so areas of each of successive layers of powder material are sintered or fully molten throughout its layer thickness. A dosing device raises successive quantities of powder to the level of the upper surface to enable a re-coater to form the layers. A separable build device unit defines build chamber opening at the upper surface, and includes a lift table and an electric drive by which the lift table is stepwise vertically adjustable so a progressively built component is lowerable into the build chamber.
US12240036B2	MnAl alloy, particles thereof, and method for production An alloy represented by the formula (MnxAly)Cz, the alloy being aluminum (Al), manganese (Mn), and carbon (C), and optionally unavoidable impurities; wherein x=56.0 to 59.0 y=41.0 to 44.0 x+y=100, and z=1.5 to 2.4. The alloy is highly suitable for forming the ε and τ phase in high purity and high microstructural homogeneity. A method for processing an alloy of formula (Mnx′Aly′)Cz′, wherein x′=52.0 to 59.0, y′=41.0 to 48.0, x′+y′=100, and z′=0.1 to 3.0, the process including providing the raw materials of the alloy, melting the raw materials, and forming particles of the alloy by gas atomization of the molten alloy.
US12240031B2	Method for producing a detent pawl Parking detent pawls are known which are suitable for securely holding a vehicle in a parked state. The aim of the invention is to provide a detent pawl for a parking lock which is characterized by a high degree of operational reliability. For this purpose, a method is proposed for producing a detent pawl with a latching section for engaging into a locking toothing, a support section for rotatably supporting the detent pawl about a rotational axis, and a locking section for resting against a locking bolt which can be moved along the detent pawl, having the following steps: providing a detent pawl blank; providing a shaping tool with a shaping contour, said shaping contour having a load section and a guide section; and shaping the detent pawl blank in a shaping direction by means of the shaping tool, wherein a depression for receiving the locking bolt is produced on the locking section, the load section defines a load region of the depression for supporting the locking bolt in a locking position, and the guide section defines a guide region of the depression for guiding the locking bolt during an actuation movement.
US12240027B2	Press brake A press brake includes elevating members each provided to respective one of a pair of support blocks so as to be able to ascend and descend, and extending vertically. A ball screw is provided to a first elevating member so as to be rotatable, and a nut member to be screwed into the ball screw is provided to a first support block. One end side of a stretch in the lateral direction is connected to an upper end portion of the first elevating member, and the other end side of the stretch in the lateral direction is connected, so as to be rotationally movable, to an upper end portion of a second elevating member. A support mechanism for supporting the stretch from below is provided to the first elevating member, and an abutting member is provided to the stretch.
US12240025B2	Sheet transitioning in spiral formed structures Spiral forming devices, systems, and methods can be used to join edges of a of a stock material, in a curved configuration, along one or more joints to form tubular structures, such as conical and/or cylindrical structures (e.g., frusto-conical structures). A planar form of the stock material can be formed from a plurality planar sheets coupled to one another in an abutting relationship. By controlling relative orientation and shapes of the plurality of planar sheets forming the stock material and/or by controlling a position of a roll bender used to curve the planar form of the stock material into the curved configuration, the curved configuration of the stock material can be controlled through transitions between sheets to facilitate rolling the sheets to a desired diameter with a reduced likelihood of dimples or other errors and to facilitate fit up between adjacent sheets in the curved configuration.
US12240024B2	Method and apparatus to control and adjust the drawing action in a rolling mill, and corresponding rolling mill Apparatus to control and adjust the drawing action in a rolling mill provided with rolling stands through which a product passes. A video monitoring system acquires frames of the product; a processing system that processes the frames and defines a normal rolling range within which the product being rolled must be positioned; identifies the position of the product and its geometric characteristics; and identifies a possible variation of the position of the product being rolled over time based on the analysis of the sequence of frames acquired. An automation system is associated with the rolling mill, configured to receive data relating to the position of the product to determine the continuation of the rolling if the product is correctly positioned in the range, or a variation of the rolling parameters if the position of the product being rolled is able to generate a cobble which is outside of the range.
US12240020B2	Pipeline pigging apparatus and methods of use An improved apparatus and methodologies of use for cleaning debris and contaminants from an interior surface or sidewall of a fluid-carrying conduit, such as a pipeline, are provided. More particularly, an apparatus and methodologies of use are provided, wherein the apparatus or ‘pipeline pig’ operates bi-directionally and comprises counter-rotating cleaning elements that are operative to enhance removal of debris and contaminants from the pipeline.
US12240018B2	Bore squeegee A novel invention squeegee cleans in a first direction, manually or by robot, the inner surface of a bore referred to as a hollow-shape, comprising a longitudinal shaft with a distal end squeegee element, and a cooperatively aligned sheath. Said squeegee element is comprised of shape conforming flexible disks in combination with shape conforming flexible tabbed fins having incrementally sized surface openings to form an ascending or descending path to incrementally collect contaminants. From said first direction the invention exits said hollow-shape distal end, cleaning said inner surface. Said sheath is selectively moved from a first proximal position to a second distal position covering said squeegee element and isolating collected contaminants. A second opposite direction retracts said invention from said hollow-shape, with manual or robotic means, by removing said isolated contaminants preventing recontamination of said inner surface. The invention can be cleaned and reused multiple times before disposal.
US12240016B2	Classifier and method of classifying This invention relates to a classifier for separating particles by size and density and a method of classifying particles by size and density. The classifier, which is also used in the method, includes an underflow outlet for conveying a first product out of the classifier; a fluidising means for introducing a fluidisation fluid into the classifier; a settling chamber for forming a hindered-settling zone, the settling chamber being in fluid flow communication with the fluidising means and the underflow outlet; a reflux chamber for forming a free-settling zone, the reflux chamber being in fluid flow communication with the settling chamber and having a cross-sectional area larger than that of the settling chamber; a launder in fluid flow communication with the reflux chamber for conveying a second product to an overflow outlet of the classifier; and an inlet conduit which projects into the classifier for introducing a feedstock into the classifier.
US12240014B2	Tine assembly A comminution apparatus comprising a hopper to collect and guide material to be comminuted onto an array of tines, the tines having an elongate body having a first end and a second end and upper and lower surfaces, a tine being secured to a tine support at a first end, a motor secured to the apparatus, preferably the hopper, the operation of the motor causing the tines to vibrate.
US12240007B2	Self-cleaning misting nozzle A spray nozzle for a steam generator of a shower steam system includes a housing defining a longitudinal bore extending to an outlet, and an atomizing member positioned adjacent the outlet. An elongated member is coupled to the housing in the longitudinal bore, and defines a pin at an end thereof. A body is slidably coupled to the housing in the longitudinal bore, and includes an opening extending therethrough. A biasing member is configured to bias the body against the elongated member by a biasing force such that the elongated member extends through the opening. The body is configured to move axially away from the elongated member toward the atomizing member in response to a pressure of a flow of water being above a threshold value so as to overcome the biasing force and allow the flow of water to pass through the opening to the atomizing member.
US12240005B2	Spray head The present disclosure provides a spray head comprising an inlet for receiving fluid and a plurality of nozzles in fluid communication with the inlet, wherein each one of the plurality of nozzles is adapted to produce, when in use, a continuous jet of fluid having an elongate transverse cross-section.
US12240004B2	Dish washer A cap is configured to couple to a nozzle of a dish washer that is configured to supply air into a tub of the dish washer. The cap includes a lower cap configured to couple to an upper end portion of the nozzle, a flow cover configured to cover a part of the upper end portion of the nozzle, and an upper cap coupled to the lower cap and configured to, based on the cap being coupled to the nozzle, be spaced apart from and positioned above the nozzle and the flow cover. The cap defines a discharge opening configured to discharge air supplied to an inner space of the cap through the nozzle.
US12240003B2	Centrifugal separator and machine comprising a centrifugal separator A centrifugal separator is configured to separate liquid and solid particles from a flow of gas generated by a machine. The centrifugal separator includes a centrifugal rotor, a hydraulic drive arrangement configured to rotate the centrifugal rotor, a hydraulic connection for connecting the hydraulic drive arrangement to a hydraulic circuit of the machine, and a connecting portion for connecting the centrifugal separator to the machine. The hydraulic connection is arranged on the connecting portion, and the connecting portion is configured to be inserted into a connecting aperture of the machine. A machine includes the centrifugal separator.
US12240000B2	Iron chelators as activators in alkaline flotation circuits The present invention is directed to a method for selectively recovering a mineral from an ore applying a promoter being a substituted ethylene diamine. Further, the present invention is directed to the use of said substituted polymeric alkylenediamine to separate a target mineral from an ore.
US12239999B1	Air quality control An electrode tube for generating electrons includes a container unit, a metal wool positioned in the container unit, and a socket, wherein the container unit is attached to the socket. The electrode tube is configured to generate electrons that bond with oxygen when electrical power is provided to the electrode tube.
US12239994B2	Granulator mill Granulator mill (1) comprising a frame (10), a cutter housing (20) with a granule chamber (22) comprising at least one non-rotatable blade (24) inside the granule chamber (22), and further comprising a rotatable rotor (30) arranged inside the granule chamber (22). The rotor (30) comprises blades (32, 34) which are arranged for cooperation with the non-rotatable blade (24) for granulating waste material to granules. A normal (n) to a first opening (26a) of the granule chamber (22) is pointing substantially vertically upwards in the normal position of use of said granulator mill (1), and characterising is that the cutter housing (20) is pivotably arranged at the frame (10) by means of a first pivot means (28), for pivoting the cutter housing (20) between the normal position of use and a cleaning position. In the cleaning position, the normal (n) of the first opening (26a) of the granule chamber (22) points towards a surface plane of the substrate.
US12239992B2	Temperature-controllable reagent cartridge and temperature control system for the same Temperature-controllable reagent cartridges and systems for controlling the temperature in such reagent cartridges are provided. An example such system may include a reagent cartridge having reagent reservoirs located at least in part within an interior plenum volume of a cartridge housing. In such an example system, each reagent reservoir may be defined, in part, by a sidewall, and a first reagent reservoir may be spaced apart from a second reagent reservoir to form a fluid flow passage between corresponding sidewalls thereof. A fluid inlet through the cartridge housing may be provided that fluidically connects the interior plenum volume with a fluid supply port of a temperature control system of an analysis instrument when the reagent cartridge is received by the analysis instrument; a fluid outlet through the cartridge housing that fluidically connects the interior plenum volume with a fluid return port of the temperature control system may also be provided.
US12239988B2	Air-matrix digital microfluidics apparatuses and methods for limiting evaporation and surface fouling Air-matrix digital microfluidics (DMF) apparatuses and methods of using them to prevent or limit evaporation and surface fouling of the DMF apparatus. In particular, described herein are air-matrix DMF apparatuses and methods of using them in which a separate well that is accessible from the air gap of the DMF apparatus isolates a reaction droplet by including a cover to prevent evaporation. The cover may be a lid or cap, or it may be an oil or wax material within the well. The opening into the well and/or the well itself may include actuation electrodes to allow the droplet to be placed into, and in some cases removed from, the well. Also described herein are air-matrix DMF apparatuses and methods of using them including thermally controllable regions with a wax material that may be used to selectively encapsulate a reaction droplet in the air gap of the apparatus.
US12239986B2	Flow cell with enhanced well imaging resolution Resolution of images used in processes such as sequencing by synthesis may be increased by structuring sites that would emit signals in the images to have different elevations. Differences in focus caused by these differences in elevation may be used to filter out background illumination, thereby providing an image in which in focus sites may be resolved even though the separation between any site and its nearest neighbor may be below the diffraction limit of the light that would be emitted.
US12239983B2	Heaters for medical devices A medical device comprising a multilayer printed circuit board (PCB) comprising a heating element on an inner layer of the PCB; a single cell electrical power source to power the heating element; and a chamber adapted to contain a liquid, at least part of said chamber being defined by a thermally conductive material configured to provide a thermal transfer interface between the chamber and the PCB.
US12239982B2	Microfluidic device and diagnostic methods for allergy testing based on detection of basophil activation Devices, methods, and kits are provided for allergy testing based on basophil activation in a blood sample. Susceptibility of an individual to an allergic reaction to an allergen is detected by collecting a blood sample from the individual and assaying for activation of basophils in response to stimulation with an allergen. In particular, a microfluidic device is provided for automating the assay for detecting basophil activation as an indication of the susceptibility of an individual to an allergic reaction as well as kits containing such a device and diagnostic methods for using such a device for allergy testing. Additionally, such a microfluidic device can be adapted for multiplexed detection of allergic responses to multiple allergens by performing assays in parallel to detect the basophil responses to each allergen.
US12239981B2	Automatic microfluidic system for continuous and quantitive collection of droplets An automatic system which combines a three-branch sorter with three independently-controlled valves and corresponding collection platforms. The subgroups of droplets are alternatively sorted into three channels followed by being pumped out into PCR tubes on the platforms. Experimentally, this system can realize an accurate collection with a large working range for both pure positive samples and mixed samples with negative ones. This technology effectively dispenses a large number of droplets into small subgroups with quantitative number, which builds the basis for digital droplet microfluidics.
US12239976B2	Vial autoloader An autoloader is disclosed for staging samples in vials to be loaded automatically into an analyzer such as a moisture analyzer for moisture analysis. The analyzer uses vials to hold small amounts of sample materials. The autoloader holds the vials in a horizontal orientation for delivery to and removal from the analyzer.
US12239968B2	Particulate filter A particulate filter includes a base material having a wall-flow structure including porous partition walls partitioning inlet and outlet cells, and wash-coating layers held inside partition walls. The wash-coating layers include inlet layers each formed from vicinity of an end portion at exhaust gas inflow side to have predetermined length and thickness and outlet layers each formed from vicinity of end portion at exhaust gas outflow side to have a predetermined length and thickness. The inlet and the outlet layers partially overlap with each other. Inlet layers of particulate filter contain substantially no noble metal catalyst, and outlet layers contain noble metal catalyst. Accordingly, PM collection performance can be easily enhanced in inlet region, and high gas distributability (pressure loss suppression performance) can be maintained in outlet region. Accordingly, it is possible to provide particulate filter capable of achieving high levels of PM collection performance and pressure loss suppression performance.
US12239965B2	Process for the production of a zeolitic material having an AEI-type framework structure via solvent-free interzeolitic conversion The present disclosure relates to a process preparating a zeolitic material having an AEI-type framework structure, wherein the framework structure comprises SiO2 and X2O3 and X is a trivalent element, and wherein the process comprises: (1) preparing a mixture comprising one or more cationic structure directing agents comprising a heterocyclic amine ring, seed crystals, and a first zeolitic material comprising SiO2 and X2O3 in its framework structure and having an FAU-type framework structure; and (2) heating the mixture to obtain a second zeolitic material comprising SiO2 and X2O3 in its framework structure and having an AEI-type framework structure.
US12239963B2	Method for desulfurizing a hydrocarbon feedstock A method of making a hydrodesulfurization catalyst having nickel and molybdenum sulfides deposited on a support material containing mesoporous silica that is optionally modified with zirconium. The method of making the hydrodesulfurization catalyst involves a single-step calcination and reduction procedure. The utilization of the hydrodesulfurization catalyst in treating a hydrocarbon feedstock containing sulfur compounds (e.g. dibenzothiophene, 4,6-dimethyldibenzothiophene) to produce a desulfurized hydrocarbon stream is also provided.
US12239960B2	Zeolite composites for water purification Zeolites having surface modification with graphene oxide, reduced graphene oxide, or a sulfide have utility in removing pollutants from a water supply. Pollutants include Persistent Organic Pollutants (POPs) and heavy metals, such as lead. POPs are adsorbed onto zeolites having surface modification with graphene oxide and/or reduced graphene oxide. Heavy metals are adsorbed onto zeolites having surface modification with a sulfide.
US12239956B2	Preparation method of super absorbent polymer composition The present disclosure relates to a preparation method of a super absorbent polymer composition. More specifically, it relates to a preparation method of a super absorbent polymer composition capable of pulverizing the hydrogel polymer to a normal particle size without agglomeration between particles by adding an additive having a specific structure, reducing manufacturing cost by simultaneously performing a drying process and a surface cross-linking process, and significantly reducing the amount of fine powder generated during the process.
US12239950B2	Process and apparatus for sequential synthesis of biological polymers A method and apparatus for nucleic acid synthesis. The method employs a device including at least one deprotection unit to carry out a step of deprotection, at least one coupling unit to carry out a step of coupling, at least one oxidation/thiolation unit to carry out a step of oxidation or thiolation, at least one capping unit to carry out a step of capping, and at least one washing unit to carry out a step of washing. A plurality of reaction vessels for nucleic acid synthesis are moved to the units in accord with a synthesis scheme for a desired nucleic acid sequence and at least two reaction vessels are simultaneously acted upon at several of the units in series.
US12239948B2	Materials based on natural pollen grains and uses thereof Disclosed herein are methods for preparing sporopollenin exine capsules (SECs) and methods for preparing composite materials that comprise SECs that utilize ionic liquid compositions. The composite materials typically include structural polymers and the SECs, and the SECs optionally may encapsulate useful materials, such as flame retardant materials, phase change materials, and therapeutic materials, such as probiotics and prebiotics. The composite materials may be prepared from ionic liquid compositions comprising the structural polymers and the SECs which optionally may encapsulate the useful materials, where the ionic liquid is removed from the ionic liquid compositions to obtain the composite materials comprising the SECs.
US12239945B2	Kitchen appliance apparatus There is provided a kitchen appliance apparatus for using air in the kitchen, comprising a housing, wherein in the housing a pump system is provided which pump system comprises, a primary port (106), a secondary port (107), a single direction air pump (101) having an inlet (102) and an outlet (103); wherein the pump system is operational in a first pump mode in which air can be sucked in via the primary port; the pump system is operational in a second pump mode in which air can be blown out via the primary port; and is operational in a third pump mode in which the pump system is alternatingly sucking in and blowing air via the primary port.
US12239937B2	Separator analysis method and apparatus An analysis method and apparatus are disclosed for analysing an absorption filtering medium that filters volatile organic substances in a process gas in a plant for dehumidifying polymer granules, with a fan that generates a flow of gas through the filtering medium, an analyzer of the total concentration of the organic carbon, a sensor to detect the pressure downstream of the filtering medium, in which the saturation state and/or the absorbent capacity and/or the deterioration over time of the filtering medium is determined by a comparison of the measured concentrations of total organic carbon in the flow of gas upstream and downstream of the filtering medium.
US12239936B2	Hydration of gas streams Techniques for humidifying a gas stream using a hydration system includes directing a gas stream through a contact zone of at least one hydration system; directing a hydration solution into the contact zone using a pump; contacting the gas stream with the hydration solution; evaporating water from the hydration solution into the gas stream to form a humidified gas stream, transporting the humidified gas stream out of the at least one hydration system; and collecting the remaining hydration solution in a hydration solution collection basin below the contact zone. The at least one hydration system is fluidly coupled to at least one downstream process and the humidified gas stream from the at least one hydration system is transported as a feed stream to the at least one downstream process.
US12239935B2	Methods and systems for adsorbing organometallic vapor Described are methods, devices, and systems useful for adsorbing organometallic vapor onto solid adsorbent material to remove the organometallic vapor from a gas mixture that contains the organometallic vapor and other vapor, particulate materials, or both.
US12239934B2	Pulse ring assembly for air cleaner systems and methods thereof A pulse ring assembly for air cleaner systems that is adapted to produce a pulse ring of gas to clean a filter element. The air cleaner system may include an outer tube and an inner tube configured to receive the inner tube such that at least a portion of an interior surface of the outer tube faces at least a portion of an exterior surface of the inner tube. The outer tube may include a pulse port extending between the interior and exterior surfaces of the outer tube into an outer tube passageway. Filtered air may be configured to flow from a first filter cartridge, through the outer and inner tubes, and to an engine intake. The system may also include a pulse jet apparatus in fluid communication with the pulse port of the outer tube and configured to direct gas through the pulse port towards the first filter cartridge.
US12239928B2	Stormwater skimmer surface drain apparatus A drainage device is provided. The device includes a novel floating surface drain or skimmer to manage draining of liquid, such as draining of water from stormwater impoundment ponds or structures.
US12239927B2	Sprayer filtering system A filtering apparatus is configured to receive pressurized fluid from a pump. The filtering apparatus has a main inlet, a main outlet, and a filtering branch comprising a first filter. An agitator of a tank from which the pump draws is configured to receive fluid flow from the filtering branch via a proportional valve and an inlet connection. A method of operating a filtering system includes influencing fluid flow from a tank to one or more nozzles via a filtering apparatus; and diverting a portion of the fluid flow through plural filters of a different mesh size back to an agitating mechanism through a lower portion of the tank.
US12239924B2	Collar having modular parts for supporting stratified filtration Systems and methods comprising using a filter element assembly. The methods comprise: placing a first sealing member in a channel formed in a first collar piece which has a first filter element coupled thereto; inserting a second filter element coupled to a second collar piece through the input orifice of the first collar piece and into the first filter element; causing the first collar piece to snap-fit engage a flange of the second collar piece; using the first sealing member to provide a seal between the first and second collar pieces which are snap-fit engaged with one another; receiving a fluid in an input orifice of the second collar piece; performing a first-stage filtering process using the second filter element to remove contaminants from the fluid; and performing a subsequent second-stage filtering process using the first filter element to further remove contaminants from the fluid.
US12239919B1	Water play toy A water play toy includes a housing, a driving device, a power module, a first conductive terminal, and a second conductive terminal. A first accommodating cavity is surrounded and formed by a side wall of the housing, and the housing is equipped with a first opening, a second opening, a liquid inlet, and a liquid outlet. The driving device is positioned in the first accommodating cavity, and the driving device is used for driving liquid to sequentially pass through the liquid inlet and the liquid outlet. The power module is positioned in the first accommodating cavity, and the power module is electrically connected to the driving device. A first end of the first conductive terminal is electrically connected to the power module and the driving device, and a second end of the first conductive terminal is exposed from the housing through an installation channel.
US12239918B2	Accessible swing A swinging playground device includes a swing platform. The swinging playground device also includes a skirt coupled to the swinging platform and fills an area below the swinging platform as the swinging platform moves in a swinging motion.
US12239913B2	Predictive analysis of gameplay trajectories Systems and methods are provided for monitoring gameplay trajectories for stopping points and applying a time-based setting. The gameplay trajectories may be based on patterns within real-time gameplay data. The server may predict one or more stopping periods within a gameplay session based on a comparison of the gameplay trajectory data to the time-based setting. Then, the setting may be applied to generate options for transitioning out of the gameplay session at a next predicted timing point.
US12239911B2	Gamified annotations during livestream Non-players can vote and comment on uploaded video clips or livestreams of video games played by video game players. The video game players that upload the clips or do the livestreaming and that then receive the most votes can be awarded digital awards. The non-players providing the best comments can also be awarded digital awards. This incentivizes these behaviors, providing ample training data in the process so that the votes and comments can be used to train a model to make inferences related to video game video. For instance, the model may be trained to provide auto-generated comments in real time as a second video game is played, where the comments are in video game domain-specific language.
US12239910B2	Information processing apparatus and user guide presentation method Methods and apparatus provide for acquiring position information about a head-mounted display; performing information processing using the position information about the head-mounted display; generating and outputting data of an image to be displayed as a result of the information processing; and generating and outputting data of an image of a user guide indicating position information about a user in a real space using the position information about the head-mounted display, where the image of the user guide represents a state of the real space in which the user is physically located, as viewed obliquely.
US12239908B2	Storage medium having stored thereon information processing program, and information processing device An example computer readable storage medium having stored thereon an information processing program executable by a computer of an information processing device which presents information corresponding to a biological signal acquired from a user, is provided. The information processing program causes the computer to function as biological signal acquiring means, motion/attitude information acquiring means, and presentation means. The biological signal acquiring means acquires the biological signal from the user. The motion/attitude information acquiring means acquires information about a motion or an attitude of the user from detecting means, in association with the biological signal acquired by the biological signal acquiring means. The presentation means performs predetermined presentation based on both the biological signal acquired by the biological signal acquiring means and the information acquired by the motion/attitude information acquiring means.
US12239907B2	Methods, systems and devices for providing portions of recorded game content in response to an audio trigger A system that incorporates the subject disclosure may include, for example, a gaming system that cooperates with a graphical user interface to enable user modification and enhancement of one or more audio streams associated with the gaming system. In embodiments, the audio streams may include a game audio stream, a chat audio stream of conversation among players of a video game, and a microphone audio stream of a player of the video game. One of the audio streams may trigger an action in the gaming system such as recording a portion of game content for a timer period. Additional embodiments are disclosed.
US12239904B2	Controller for a games console A hand held controller for a games console comprising an outer case and at least one control located on the controller. The controller is shaped to be held in at least one hand of a user such that the at least one control is operable by the user. The at least one control extends through an aperture provided in the outer case, and wherein the controller comprises a removable buffer mounted within the aperture.
US12239903B2	Controller with sensor-rich controls Described herein are controllers with sensor-rich controls for enhanced controller functionality. An example control may include a pressure sensor that is configured to detect an amount of a force of a press on a cover of the control based at least in part on a proximity of a metal layer to the pressure sensor. This control may further include a touch sensor for detecting an object contacting the cover of the control. Additional embodiments disclose, among other things, integrated trackpads and D-pads, as well as backlighting features that indicate a functional state of the controller.
US12239900B2	Control assembly for portable electronic device A control assembly is adapted for an electronic device and includes two controllers and a link mechanism, the two controllers are configured to be removably installed on the electronic device, the link mechanism includes a retractable mechanism receptacle and two flexible parts, the two controllers are connected to the retractable mechanism receptacle respectively via the two flexible parts, and at least part of each of the two flexible parts is retractably accommodated in the retractable mechanism receptacle.
US12239893B2	Speed-pong game A portable game includes a lower table forming a circular playing surface and an edge having a diameter D1, an upper table forming a circular playing surface and an edge having a diameter D2, wherein D1>D2. A vertical support member interconnects the lower and upper tables. Cup positioning markers are formed on said first and second table playing surfaces for locating said beverage cups thereon. An elongated barrier assembly extends vertically above said playing surface and horizontally bisects the upwardly firing playing surface. The vertical barrier is operative to define discrete opposed team play areas enabling a plurality of teams to play simultaneously on opposed sides of said barrier and to prevent horizontal travel of ping pong balls between opposing team play areas. The barrier is supported by at least one vertically elongated support stanchion slip-fit within the playing surfaces to enable selective removal and insertion thereof.
US12239889B2	Binder jet printed golf club components with lattice structure Golf club components with complex such as lattice structures, beam structures, and complex surface-based structures, are described herein. A binder jet machine is used create complex structures within these golf club components to optimize weighting, sound, and performance of golf club heads. These components may be manufactured using a method that preferably includes the steps of designing a golf club head component in CAD using optimization software, printing the component from a powdered material, and then removing excess powder from the component via port holes that extend into an external surface of the component and communicate with interior voids within the component.
US12239888B2	Golf club Aspects of the invention are directed to golf club having a crown, a sole, a face, and a primary alignment feature hard tooled into the golf club head. In some embodiments the golf club has a primary alignment feature comprising a line delineating a transition between at least a portion of the crown having an area of contrasting shade or color with a shade or color of the face. The primary alignment feature is hard tooled into the golf club head with the face of the golf club body.
US12239885B2	Dimple patterns for golf balls The present invention provides a method for arranging dimples on a golf ball surface in which the dimples are arranged in a pattern derived from at least one irregular domain generated from a regular or non-regular polyhedron. The method includes choosing control points of a polyhedron, generating an irregular domain based on those control points, packing the irregular domain with dimples, and tessellating the irregular domain to cover the surface of the golf ball. The control points include the center of a polyhedral face, a vertex of the polyhedron, a midpoint or other point on an edge of the polyhedron and others. The method ensures that the symmetry of the underlying polyhedron is preserved while minimizing or eliminating great circles due to parting lines.
US12239884B2	User interfaces for group workouts The present disclosure generally relates to sharing workout content on electronic devices.
US12239882B2	Program products, methods, and systems for providing location-aware fitness monitoring services Program products, methods, and systems for providing location-aware fitness monitoring services are disclosed. In an embodiment of the present invention, a method of displaying a route traversed by an athlete equipped with a location-aware portable fitness monitoring device includes the steps of (a) receiving data describing a plurality of satellite navigational system waypoints that are acquired as the athlete engages in a fitness activity, (b) identifying a map area based on a location indicated by the data describing the plurality of satellite navigational system waypoints, (c) determining the route traversed by the athlete based on the data describing the plurality of satellite navigational system waypoints and based on the location of one or more known paths associated with the map area, and (d) displaying the route traversed by the athlete on top of the map area.
US12239877B2	Exercise apparatus The present disclosure provides an exercise apparatus with a mobility mat and an orthopedic device. The mobility mat can have a plurality of segments or have a single piece construction. The mobility mat includes a body provided with a plurality of assistive features, such as hand holds, foot holds, resistance bands, various exercise grips, and a contoured cushion. These assistive features can be removably attached to the mobility mat using grommets formed in the mat body and holding tabs that can be secured in the grommets. The mobility mat can be further configured to couple with the orthopedic device. The orthopedic device can have an inclined face and a plurality of remaining faces including various additional assistive features.
US12239872B2	Safety mechanism for an adjustable dumbbell An adjustable kettlebell includes a cradle safety mechanism and a kettlebell safety mechanism. The cradle safety mechanism includes a position sensor that detects whether the kettlebell is in the cradled position and prevents a motor from rotating to change the weight of the kettlebell if the kettlebell is in the uncradled position. The kettlebell safety mechanism includes a dial retractable into the handle of the kettlebell. When the dial is retracted into the kettlebell, a selection mechanism cannot be rotated to change a weight of the kettlebell.
US12239859B2	Ratcheting strap adjuster A method of assembling a ratcheting strap adjuster comprises inserting a distal end of a rotation assembly through first and second apertures in respective first and second side plates of a frame, with a proximal end of the rotation assembly positioned proximate the first side plate and the distal end positioned proximate the second side plate. A captive member is movably connected to the second side plate proximate the distal end, wherein the captive member is movable between an engaging position and a releasing position, and wherein an engaging portion of the captive member is configured and arranged to selectively engage the distal end of the rotation assembly in the engaging position.
US12239855B2	mmWave array and implanted susceptors for hyperthermia-based anti-cancer treatments Methods and systems for hyperthermia-based anti-cancer treatments are disclosed herein. One disclosed system for hyperthermia-based anti-cancer treatments includes an array of millimeter wave amplifier integrated circuits having an output energy, one or more medical grade implantable susceptors, and a beam steering controller for the array of millimeter wave amplifier integrated circuits that is configured to steer the output energy of the array of millimeter wave amplifier integrated circuits into the one or more medical grade implantable susceptors.
US12239852B2	Motion synchronized arc radiotherapy Apparatus and methods for planning and/or delivering radiation treatment and controlling a radiation delivery system are described. Apparatus for delivering radiation treatment includes a radiation source, a drive connected to move the radiation source along a trajectory, a stored radiation treatment plan specifying a plurality of beam ON segments and beam OFF portions of the trajectory interleaved with the plurality of beam ON segments, and a monitor connected to detect progress of a physiological cycle of the patient, the physiological cycle has cycles that include quiescent periods. One or more data processors are connected to control the drive to advance the radiation source along the trajectory, control the radiation source to deliver radiation in each of the plurality of beam ON segments of the trajectory and to deliver no or negligible radiation in each of the beam OFF portions of the trajectory, process an output of the monitor to estimate a time for a next one of the quiescent periods, and control a speed at which the radiation source is advanced along the trajectory to cause the radiation source to arrive at a start of a next one of the beam ON segments at a time that coincides with the next one of the quiescent periods.
US12239849B2	Checking quality of a treatment plan It is provided a method for checking quality of a treatment plan, wherein a treatment plan specifies a distribution of radiation to thereby provide radiation to a planning target volume. The method is performed by a quality assurance device and comprises the steps of: obtaining a treatment plan and a corresponding first dose, the treatment plan having been calculated in a treatment planning system, the first dose being a predicted dose to be deposited in the patient using the treatment plan; initiating a calculation of a secondary dose, being a dose deposited by the treatment plan, using a secondary dose calculation algorithm; repeatedly calculating a confidence interval of a comparative statistical measurement by comparing the first dose and the secondary dose over a defined geometric volume; and interrupting the calculation of the secondary dose when the confidence interval is better than at least one predefined criterion.
US12239847B2	Hybrid trajectory and beam angle optimization for external beam radiation therapy A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based on the BEV scores; determining a BEV region connectivity manifold based on the BEV regions; determining a set of treatment trajectories based on the BEV region connectivity manifold; and determining one or more IMRT fields. Each treatment trajectory defines a path through a set of vertices in the DCS. Each IMRT field defines a direction of incidence corresponding to a vertex in the DCS.
US12239845B2	Phototherapeutic apparatus for focused UVB radiation and vitamin D synthesis and associated systems and methods The present disclosure is directed to a phototherapeutic apparatus for focused UVB radiation and vitamin D synthesis and associated systems methods. In one embodiment a phototherapeutic apparatus can include a housing at least partially defining an irradiation zone, and an ultraviolet (UV) radiation source carried by the housing. The irradiation zone can be configured to accommodate at least a portion of a human patient. The phototherapeutic apparatus can further include a filter between the UV radiation source and the irradiation zone. The filter can be configured to at least substantially remove UV radiation outside of a predetermined spectrum centered at about 297 nm and having a bandwidth of at most 10 nm.
US12239843B2	System and method for operating a plasma jet configuration The invention relates to a system (1) for generating and controlling a non-thermal atmospheric pressure plasma, comprising: —a discharge space (10) into which a working gas can be introduced via a first opening (12), wherein a plasma (5) can be generated in the discharge space (10), wherein the discharge space (10) has a second opening (14), so that the plasma (5, 6) can exit from the discharge space (10) through this second opening (14) and —at least one high-voltage electrode (20) for generating an electromagnetic field for generating a plasma (5) in the discharge space (10). The plasma (5, 6) exiting through the second opening (14) is controlled by a throughflow controller (40) of the system (1), which throughflow controller (40) is designed to adjust a volume flow (60) of the working gas through the first opening (12) from a working gas source (50) into the discharge space (10). In this case, the throughflow controller (40) is further designed to assume at least a first state and a second state, wherein in the first state no working gas is supplied from the working gas source (50) to the discharge space (10), so that no plasma (5) exits from the second opening (14) even when there is a generated electromagnetic field in the discharge space (10), and wherein in the second state the working gas is supplied from the working gas source (50) to the discharge space (10), a plasma (5) is generated in the discharge space (10) and the plasma (5, 6) exits from the second opening (14).
US12239839B2	Methods and apparatus to stimulate the heart A method and apparatus for treatment of hypertension and heart failure by increasing secretion of endogenous atrial hormones by pacing of the heart. Pacing is done during the ventricular refractory period resulting in premature atrial contraction that does not result in ventricular contraction. Pacing results in the atrial wall stress, peripheral vasodilation, ANP secretion. Concomitant reduction of the heart rate is monitored and controlled as needed with backup pacing.
US12239832B2	Manner of raising alarm for a heart support system A heart support system is provided includes a control unit and sound-generating devices, said control unit configured to detect and process alarm events and to carry out control tasks in the heart support system. The heart support system further includes a storage device configured to store one or more defined alarm signal time curves and one or more alarm priorities. Each alarm signal time curve and each alarm priority is assigned to an alarm event. A sound-generation controller is configured such that when an alarm event is detected, the controller overlays a volume time curve onto the alarm signal time curve assigned to the alarm event in the storage device, said volume time curve based on the alarm priority assigned to the respective alarm event in the storage device and the length of time since the detection of the alarm event.
US12239831B2	Integrated adjustable multi-pump mechanical circulatory support device A mechanical circulatory support device is provided. The device has a housing containing separate first and second pumps. Each pump having an inlet, an outlet, and an impeller. The device also having a switching mechanism located within the housing and movable from a first position to a second position to divert blood flow within the housing to an inlet of one of the pumps and/or to bypass blood flow relative to one of the pumps within the housing.
US12239830B2	Adaptor for connecting a connector to a drug delivery device An adaptor for connecting a drug delivery device to a connector provided with an external thread is disclosed. The adaptor includes a globally tubular body having a proximal region and a distal region, the proximal region being provided with an engagement element for mounting the adaptor on the drug delivery device. The distal region is provided on an inner wall of the distal region with an internal thread intended to cooperate with the external thread so as to connect the connector to the adaptor, the internal thread defining an internal thread crest. The internal thread crest is provided with at least one deformable radial end part configured so as to be radially deformed when the connector is screwed into the adaptor. Also disclosed is a drug delivery device including the adaptor and a method for connecting the connector to the adaptor.
US12239829B2	Multi-dose dispenser A multi-dose dispenser comprising an inner housing (16) and an outer housing (12), the inner housing (16) being movable within the outer housing (12) for a defined distance, a plunger rod (20) comprising a shaft (66) mounted within the inner housing (16), the shaft (66) having a plurality of spaced apart teeth (68) formed on the shaft (66), an actuator (22) located at one end of the shaft (66), the inner housing (16) having at least one pawl (70) arranged to engage with the teeth (68), a syringe (74) mounted interiorly of the inner housing (16), the syringe (74) being arranged such that the shaft (66) engages with a plunger within the syringe (74), and a spring member (18), the spring member (18) being biased between the inner housing (16) and the outer housing (12).
US12239824B2	Needle-free injector with gas bubble detection A needle-free injector includes a housing, a cartridge positioned within the housing, and a plunger slidably coupled to and disposed within the chamber, a motor operatively coupled to the plunger, the motor operable to actuate the plunger in the chamber, and a controller operatively coupled to the motor. The controller is operable to selectively operate the plunger according to any of a first delivery profile, a second delivery profile, and a third delivery profile. The controller may transition from the first delivery profile to the second delivery profile responsive to compression of a gas in the chamber, e.g., upon detecting a spike in a measured current applied to the motor. The controller may transition from the second delivery profile to the third delivery profile responsive to detecting a steady state condition between the measured current and a velocity of the plunger. Methods of delivering an injectate using the needle-free injectors are provided. Methods of facilitating needle-free injection of an injectate using the needle-free injectors are also provided.
US12239823B2	Drug mixing and delivery system and method The present disclosure provides methods of preparing a medical solution. In some aspects, the medical solution can be prepared from mixing a first liquid with a second liquid or mixing a solid component with a liquid in an autoinjector. In some aspects, the heat released from the mixing can promote solubility of a dry medicament in the solution.
US12239819B2	Method and system to treat acute decompensated heart failure A apparatus and method to treat patients with acute decompensated heart failure (ADHF), heart failure or another fluid overload condition, that includes: administrating a diuretic to the patient to increase urine output of the patient; monitoring a rate or amount of urine output by the patient after administration of the diuretic; infusing a hydration liquid into the patient to induce an increase in the urine output; and adjusting the rate or amount of the hydration liquid infused into the patient to achieve a target fluid loss in the patient.
US12239816B2	Drug delivery device cassette A drug delivery device may include a cassette with a needle assembly and a cartridge. The cassette is configured to couple and decouple from a reusable module. The device may also comprise an orientation mechanism to orient the cassette in relation to another device, such as a reusable housing. The device may comprise an extendable and retractable needle assembly. The cassette configuration is adapted to have a stopper with a short travel (no more than 14 mm) to deliver 1 mL of medication. The cassette may have a ratio of height to diameter from 2:1 to 1:1. The cassette may include a pair of drivable interfaces for being driven to actuate the stopper to expel medication and to drive the needle assembly between a retracted and extended configuration for controlled fluid communication between the needle and reservoir.
US12239815B2	Tub for the packaging of a plurality of nests of plunger stoppers with guiding features ensuring a reliable location of the nests within the tub A nest and tub arrangement for the storage of medical device components including a tub having a plurality of guide elements extending from at least one surface of the tub and into the interior of the tub, and at least one nest having a plurality of receptacles for the storage of a plurality of medical device components therein. The at least one nest is sized and configured for placement within the tub such that the plurality of guide elements align and removably retain the at least one nest within the tub.
US12239809B2	Surgical skin preparation device with timed indicator A surgical skin preparation device for applying an antiseptic composition to skin of a patient includes an applicator configured to absorb the antiseptic composition, the applicator having a top surface and a bottom surface, the bottom surface configured to apply the antiseptic composition to the skin of the patient, and an indicator. The indicator includes a first layer of a first material configured to wick the antiseptic composition, the first material being opaque in a first state and transparent or translucent in a second state, and a second layer of a non-wettable material, the second layer having at least one indicia that is visible to a user when the first layer is in the second state.
US12239805B2	Spinal drainage kit container A spinal drainage kit container includes a body, lid, and hinge. The body includes a peripheral portion and a first grip configured to be gripped when the lid is to be opened. The first grip is at a first corner of the body, opposite the hinge, and has a first protrusion in a first direction. The lid includes a contact configured to come into contact with the peripheral portion when the lid is closed, and a second grip connected to the contact and configured to be gripped when the lid is to be opened. The second grip is at a second corner of the lid, which overlaps with the first corner when the lid is closed; and the second grip has a second protrusion that protrudes in a second direction orthogonal to the first direction and does not overlap with the body when the lid is closed.
US12239802B2	Catheter management device An elongate shaft management device has an upper plate and a lower plate. The lower plate has at least one groove that is sized to receive the elongate shaft. The at least one groove in the lower plate cooperates with the upper plate to capture the elongate shaft and prevent movement of the elongate shaft. The upper plate is releasably coupled to the lower plate to provide access to the elongate shaft and allow it to be manipulated.
US12239801B2	Protective dressing A transparent dressing includes a portion without adhesive to allow placement over a catheter to reduce any effect of placing and positioning of a catheter at the time of removal of the dressing. The transparent dressing may include at least one tab for handling and removing the dressing, the at least one tab being positioned on at least one outer edge of the dressing.
US12239799B2	Dual lumen sheath for arterial access A sheath assembly for the insertion of a percutaneous pump includes a tubular sheath body dimensioned for insertion into a blood vessel through a vessel aperture. The tubular sheath body includes a wall having a proximal end portion, a distal end portion, a longitudinal axis, an outer surface, an inner surface defining a first lumen substantially parallel to the longitudinal axis, and a second lumen disposed within the wall between the inner surface and the outer surface and extending from the proximal end portion to the distal end portion. The first lumen is dimensioned to allow passage of a portion of the percutaneous pump, and the second lumen is dimensioned for passage of a guidewire. A stylet is removably positioned to substantially occlude the second lumen. The stylet has a proximal end releasably secured to the sheath assembly.
US12239798B2	Guide extension catheter Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal member having a proximal end, a distal end, and a proximal diameter. The guide extension catheter may additionally include a collar member attached to the distal end of the proximal member, the collar member comprising a base portion and one or more ribs connected to the base portion and extending distally away from the base portion. In still some additional embodiments, the guide extension catheter may further include a distal sheath member attached to the collar member, the distal sheath member having a distal diameter larger than the proximal diameter.
US12239792B2	Method and device for controlling the temperature of the gas flow in medical devices Disclosed are methods for measuring and controlling the gas temperature in medical procedures. In embodiments of the disclosed methods a gas is supplied to a patient using a gas supply device and a supply line. A heating system heats the gas using a heating wire prior to the gas being provided to the patient. A controller electrically controls the heating power of the heating wire based on an estimated value of a temperature at an exit of the heating system obtained from a mathematical estimation system, wherein a resistance of the heating wire is an input variable of the mathematical estimation system.
US12239791B2	Hypoxia training device The present invention includes a device for hypoxia training including a breathable gas source; a mask in fluid communication with the breathable gas source; a mask-state detector that uses one or more criteria to determine if the mask is being worn by a subject, wherein the mask-state detector is capable of communicating an indication of a mask-off state or a mask-on state; a flowmeter in fluid communication with the mask and coupled to the mask-state detector; and a pressure regulator in fluid communication with the mask and with the breathable gas source, and coupled to the mask-state detector, wherein the pressure regulator sets a first pressure at the mask when the mask-state detector communicates an indication of a mask-off state or a second pressure at the mask when the mask-state detector communicates an indication of a mask-on state.
US12239790B1	Modular elbow frame assembly for a ventilator A modular elbow frame assembly for a ventilator, which includes an elbow, a hose, a tubular connector, an external connecting component, a frame, a noise reduction element, a quick-release device. The modular elbow frame assembly for a ventilator can be used in conjunction with a patient interface cushion and a ventilator tube. In this system, the quick-release device is integrally formed with the elbow. The assembly involves a modular design that makes the elbow detachable, allowing the replacement of the elbow with exhaust holes of different numbers or diameters for patients to adjust airflow pressure into the airway. The quick-release device enables the rapid detachment between the elbow and the frame or patient interface cushions. Patients can choose whether to include the noise reduction element and whether to connect the ventilator tube via a hose or directly through a tubular connector.
US12239788B2	Patient interface A patient interface, such as a nasal cannula, including a body to be positioned upon a user (preferably such as a user's face), the body including at least one (and preferably a pair of) nasal prong(s), the or each nasal prong including a lumen capable of being fluidly connected thereto for fluid communication with a supply of breathable gas, the or each nasal prong to be in a configuration either inserted into, or to direct a flow of gas toward, a nare or the nares of the user's nose, wherein the body includes at least one element responsive to force(s) or movement(s), or both, experienced by at least a first region of the patient interface.
US12239787B2	Apparatus for enabling blind endotracheal tube or guide wire insertion into the trachea An intubation assistance device facilitates insertion of an endotracheal tube or a guide wire into a patient's trachea without requiring a laryngoscope. The device includes a curved flexible tubular member that has a proximal portion having a proximal end, a distal portion having a distal end, and a curved portion between the proximal portion and the distal portion. A lumen extends from the proximal end of the tubular member and terminates in the curved portion of the tubular member. The lumen is sized and shaped so that an endotracheal tube and/or a guide wire is axially moveable through the lumen. A ramp is disposed at a distal end of the lumen, and is angled to facilitate insertion of the endotracheal tube and/or guide wire into the patient's trachea. The distal portion of the tubular member includes an esophageal protrusion that is configured to be inserted in the patient's esophagus.
US12239780B2	Bi-dose nasal spray A nasal spray containing an aqueous solution or a fluid with an anxiolytic or anticonvulsant substance, wherein the nasal spray is characterized in that with the nasal spray, two sprays with each an equivalent, defined volume of the aqueous solution or liquid of the active agent, can be intranasally administered to a patient. The nasal spray allows for an administration, independent of the spatial orientation of the nasal spray in any position of the patient (standing upright, sitting, lying or in any intermediate position). The nasal spray can be used directly without prior activation. It is apparent from the nasal spray whether a spray or even a second spray has been made with the nasal spray. A spray can be administered one-handed by the patient or a third person. The active agent is midazolam or a salt thereof.
US12239769B2	Multi-function air purifying and sterilizing system A multi-function air purifying and sterilizing system for filtering and/or sterilizing air comprises: (a) a casing having an air inlet at one end of the casing and an air outlet at the other end of the casing, (b) electrostatic means for attracting particulate matter including biological contaminants, and thus, for removing the particulate matter and the biological contaminants from an air stream passing therethrough, the electrostatic means comprising at least one spiked surface, the at least one spiked surface inducing corona discharge and/or cold plasma when high voltage is applied, the corona discharge and/or the cold plasma producing ozone molecules, (c) at least one energy source for producing rays, the at least one energy source is inter-displaced within the electrostatic means to have the produced rays in close proximity to the electrostatic means for maximizing the at least one energy source efficiency in demolishing the particulate matter and the biological contaminants depositing on the electrostatic means, and/or converting the ozone molecules to hydroxyl radicals, the hydroxyl radicals disinfecting and inhibiting the biological contaminants and/or odors, and/or gases in the air stream, the hydroxyl radicals is spreadable within a confined space, thus, disinfecting biological contaminants and/or odors, and/or gases within a confined space.
US12239767B2	Dissolvable microneedle arrays for transdermal delivery to human skin A method of forming a microneedle array can include forming a sheet of material having a plurality of layers and micromilling the sheet of material to form a microneedle array. At least one of the plurality of layers can include a bioactive component, and the microneedle array can include a base portion and plurality of microneedles extending from the base portion.
US12239751B2	UV pathogen control device and system A UV microorganism inhibiting device that includes a housing having an interior, and a front and back that defines a length; at least one UV light source located within the interior of the housing; a pressurized air source to produce pressurized air; an inlet for introducing pressurized air into the interior of the housing; a reflective surface within the interior of the housing; and an outlet opening for allowing UV light and an air and ozone mixture to pass from the interior of the housing to outside the housing.
US12239750B2	Fertility kits with sterile syringes and collection jars, method of sterilization and use A method of sterilizing an Intracervical Insemination (ICI) fertility kit, for use in performing self-insemination. Each sterile kit comprises: one to three sets of individually wrapped sterile, disposable, syringes and optionally semen collection jars; printed instructions; and a QR code. The collection jar comprises a snap-on lid, and an inner surface with seamless edges to prevent semen residue. The syringes and optionally the jars are sealed in plastic wraps permeable to air and gas, and impermeable to pathogens; and are sterilized via gamma radiation or ethylene oxide. Fresh or frozen, unwashed or washed, semen is deposited into the jar, pulled into the syringe, and administered cervically during a user's maximum monthly level of luteinizing hormone. The syringe distal end is designed to push all semen out of the syringe then plug the end closed, while preventing semen residue from collecting within the syringe. Large circular syringe handles facilitate stable handling.
US12239748B2	Absorbent material, and system and method of making same A fiber-SAP particle includes a superabsorbent core particle (SAP core particle) and a plurality of fibers attached to the SAP core particle and extending therefrom. The fiber-SAP particles may be formed in a fluidized bed chamber using a spray drying process. The fiber-SAP particles may be incorporated into absorbent cores and articles, such as in disposable diapers.
US12239747B2	Wound dressing layer for improved fluid removal Described herein are embodiments of a wound dressing layer. The wound dressing layer may include an open-cell foam. The foam may have a 50% compression force deflection of not more than about 4.8 kPa. The foam may also have a density of at least 24 kg/m3. The foam may exhibit a density increase of a factor of at least 12 at about −75 mmHg.
US12239742B2	Polynucleotides encoding Citrin for the treatment of Citrullinemia type 2 The invention relates to mRNA therapy for the treatment of Citrullinemia Type 2 (“CTLN2”). mRNAs for use in the invention, when administered in vivo, encode human Citrin, isoforms thereof, functional fragments thereof, and fusion proteins comprising Citrin. mRNAs of the invention are preferably encapsulated in lipid nanoparticles (LNPs) to effect efficient delivery to cells and/or tissues in subjects, when administered thereto. mRNA therapies of the invention increase and/or restore deficient levels of Citrin expression and/or activity in subjects. mRNA therapies of the invention further decrease levels of biomarkers associated with deficient Citrin activity in subjects, namely ammonia and/or triglycerides.
US12239739B2	Oral dosing of GLP-1 compounds The present invention relates to improved uses of glucagon-like peptide-1 (GLP-1) peptides in oral therapy.
US12239736B2	Polymersomes comprising a soluble encapsulated antigen as well as methods of making and uses thereof The present invention relates to polymersomes comprising a soluble encapsulated antigen, wherein said soluble encapsulated antigen is selected from the group consisting of: a polypeptide, a carbohydrate, a polynucleotide and combinations thereof. The present invention further relates to a method for production of encapsulated antigens in a polymersome as well as to polymersomes produced by said method. The present invention further relates to compositions comprising a polymersome of the present invention, isolated antigen presenting cells or hybridoma cells exposed to the polymersome or composition of the present invention. The present invention also relates to vaccines comprising polymersomes of the present invention, methods of eliciting an immune response or methods for treatment, amelioration, prophylaxis or diagnostics of a cancer, autoimmune or infectious disease, comprising providing polymersomes of the present invention.
US12239733B2	Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose Disclosed is a method of treatment of a disease associated with abnormal protein aggregation comprising parenterally administering pharmaceutical formulations comprising trehalose. Also disclosed is an injectable aqueous pharmaceutical formulation comprising a therapeutically effective amount of trehalose.
US12239732B2	Anti-CD37 immunoconjugate and anti-CD20 antibody combinations Methods of administering immunoconjugates that bind to CD37 (e.g., IMGN529) in combination with antibodies that bind to CD20 are provided. The methods comprise administering an anti-CD37 immunoconjugate (e.g., IMGN529) and an anti-CD20 antibody to a person in need thereof, for example, a cancer patient.
US12239727B2	Compositions for use in the treatment of photosensitivity Compositions comprising melatonin and/or derivatives thereof for topical application to the skin for use in the treatment of photosensitivity of whatever cause are described.
US12239726B2	Process for dyeing or bleaching keratin fibers using particular amino acids in high concentration The present invention relates to a process for dyeing or bleaching keratin fibers, comprising the application to the keratin fibers of a composition comprising a high content of one or more particular amino acids followed by the application of a dyeing or bleaching composition.
US12239724B2	Lip composition Disclosed are lip compositions and methods of their use that include a glutamide derivative and a hydrogenated film forming polymer. The glutamide derivative includes dibutyl lauroyl glutamide and the lip compositions comprise an effective amount of dibutyl lauroyl glutamide to moisturize skin. The lip compositions are further configured to soften skin and provide a high-shine and low tack layer on lips.
US12239719B2	Fluorochemical targeted therapies The present invention is directed to compositions and methods targeting cells in a subject harboring conditions or at risk for conditions that would benefit from gas-based diagnostic and therapy. The present invention relates to the use of fluorochemical compositions and methods of delivery that result in retention of the fluorochemical composition and any bioactive agent, including gaseous substances, delivered in combination with the fluorochemical composition.
US12239714B2	Phosphatidylserine-binding conjugates Presented herein, in certain aspects, are conjugates capable of binding phosphatidylserine (PS) and toll-like receptors (TLRs), and their uses for the treatment of selected diseases and disorders, such as cancer.
US12239712B2	Combination therapy for the treatment of liver disease The invention relates to pharmaceutical compositions, and more specifically to pharmaceutical compositions comprising at least one fatty acid-bile acid conjugate and at least one thyroid hormone receptor agonist or thyroid hormone mimetic or pharmaceutically acceptable salts thereof, and use of such compositions in methods of treating, stabilizing or lessening the severity or progression of a liver disease including fibrosis, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and comorbidity ties associated with a liver disease.
US12239711B2	Cereblon ligands and bifunctional compounds comprising the same The description relates to cereblon E3 ligase binding compounds, including bifunctional compounds comprising the same, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present disclosure. In particular, the description provides compounds, which contain on one end a ligand which binds to the cereblon E3 ubiquitin ligase and on the other end a moiety which binds a target protein such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. Compounds can be synthesized that exhibit a broad range of pharmacological activities consistent with the degradation/inhibition of targeted polypeptides of nearly any type.
US12239708B2	Dry powder inhalation formulation and its use for the therapeutic treatment of lungs A dry powder inhalation formulation includes at least one active pharmaceutical ingredient (API) and a lipid matrix having at least one triglyceride chosen in the group consisting of monohydroxystearin, dihydroxystearin, trihydroxystearin and their mixture and its manufacturing method.
US12239706B2	Method and system for protecting monarch butterflies from pesticides A method and system for the treatment of Monarch butterflies (Danaus plexippus Kluk (Lepidoptera: Nymphalidae) to protect them from various life-threatening conditions, including the negative effects of various pesticides, provides Monarch butterflies with the ability to assimilate and degrade pesticides such as neonicotinoids and fipronil. Certain embodiments involve the inoculation of flowers by honey bees with desired bacteria that are able to degrade pesticides, such that when Monarch butterflies visit such flowers, they are exposed to such bacteria, transforming the microbiome of the Monarch butterflies so that pesticides can be degraded, thus enhancing the health of the Monarch butterflies.
US12239702B2	Vaccination with replicon particles and oil adjuvant The present invention relates to vaccination against animal pathogens using alphavirus-replicon RNA particles and oil adjuvants. To a vaccine, and a kit of parts comprising the replicon particles and the oil adjuvant. Also to methods and uses of making and using the vaccine and the components of the kit.
US12239701B2	Respiratory syncytial virus mRNA vaccine Provided herein are a respiratory syncytial virus (RSV) vaccine composition including a messenger ribonucleic acid (mRNA) including an open reading frame (ORF) encoding RSV mutant F B strain protein, and optionally a mRNA including an ORF encoding RSV mutant F A strain protein, and a method of inducing immune response against RSV by administering an effective amount of the RSV vaccine composition to a subject in need thereof. Provided herein are also a respiratory syncytial virus (RSV) and human metapneumovirus virus (hMPV) vaccine composition including a mRNA including an ORF encoding RSV mutant F A strain protein, a mRNA including an ORF encoding RSV mutant F B strain protein, and a mRNA including an ORF encoding hMPV F protein, and a method of inducing immune response against RSV and hMPV by administering an effective amount of the RSV and hMPV vaccine composition to a subject in need thereof.
US12239698B2	HIV vaccine immunogens This disclosure provides HIV immunogens and use thereof for generating an immune response in a subject. Also disclosed is a method of isolating anti-HIV antibodies and use thereof. This disclosure further provides a method for treating or preventing a human immunodeficiency type 1 (HIV-1) infection in a subject using the disclosed HIV immunogens and/or antibodies.
US12239697B2	Virus-like particle conjugates This invention is directed to immunogenic composition, conjugates, virus-like particles (VLP) compositions, vaccines and methods directed to the treatment and/or prevent of infection by Human Papillomavirus.
US12239694B2	Methods and compositions for improved cognition Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides.
US12239691B2	Formulations for oral administration of active agents Pharmaceutical compositions comprising a therapeutically active agent and an absorption enhancer such as NAC, NAD, 5-CNAC, 4-MOAC, 4-CNAB or a salt thereof, for use in the treatment of a condition treatable by said therapeutically active agent, are provided. The compositions are for concomitant oral administration of two or more of the unit dosage form, which form together a therapeutically effective amount of the therapeutically active agent and an effective amount of the absorption enhancer. Multi-dose compositions comprising the two or more of the unit dosage form are also provided.
US12239685B2	Composition The invention provides inter alia an aqueous solution composition of pH in the range 6.0 to 8.0 comprising: —daptomycin or an analogue thereof, or a salt thereof; —a divalent metal cation; and —one or more salts which are not divalent metal cation salts or amino acid salts or buffer salts at a total concentration of 300 mM or more.
US12239677B2	Therapeutic bacteriophage compositions for treating Staphylococcus infection The present disclosure relates to a bacteriophage composition comprising one or more (suitably two or more, or three) obligately lytic bacteriophages capable of infecting and lysing Staphylococcus aureus, and use of the same for treating Staphylococcus aureus bacterial infections.
US12239676B2	Synbiotic composition for improving immune response and antioxidant capacity during aging and a process for the preparation thereof The present invention provides a symbiotic combination of i) a probiotic micro-organism comprising of a Lactobacillus strain, and ii) a catechin component comprising EGCG that acts as a second generation symbiotic with synergistic effects in improving the immune response and antioxidant capacity during aging that may beneficially affect the health of elderly.
US12239673B2	Composition comprising pediococcus pentosaceus for use in treatment and/or prevention of food and/or alcohol poisoning The present invention relates to a composition comprising Pediococcus pentosaceus, one or more yeast, wherein a weight ratio of Pediococcus pentosaceus:yeast is between 0.01 to 0.5:1, and optionally one or more minerals, sugar and pharmaceutical acceptable excipients, additives and/or adjuvants. The invention also relates to a use of the composition as food supplement or in treatment and/or prevention of a disease in a mammal, such as a human and a use in treatment and/or prevention of food and/or alcohol poisoning in a mammal.
US12239670B2	Use of stem cells expressing mesenchymal and neuronal markers and compositions thereof to treat neurological disease The invention provides pharmaceutical compositions comprising human immature dental pulp stem cells (hIDPSCs) wherein the hIDPSCs express CD44 and CD13. The invention also provides methods of treating a neurological disease or condition comprising systemically administering to a subject a pharmaceutical composition comprising hIDPSCs wherein the hIDPSCs express CD44 and CD13. For example, for treating neurological diseases or conditions including supporting the neuro-protective mechanism in subjects diagnosed with early HD or repairing lost DA neurons in subjects diagnosed with PD.
US12239667B2	Extracellular vesicles isolated from genetically modified cells over-expressing SERPINB3 for use in medicine The present invention concerns the therapeutic use of extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3. In particular, said therapeutic use aimed at the treatment of acute pathologies characterized by ischemic or inflammatory tissue damage or by cell injury due to oxidative stress, such as cardiac, cerebral, intestinal, renal or limb ischaemia. Further examples of use consist of the preservation of transplant organs, including heart, lung, liver, bladder, pancreas and intestine. In a further aspect the invention relates to the use of a pharmaceutical composition comprising extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3 and a pharmaceutically acceptable vehicle.
US12239659B2	Methods of administering safe colon cleansing compositions Disclosed herein are methods of administering compositions comprising a mixture of salts that induce purgation of the colon and are useful to cleanse the colon. Furthermore, the disclosed methods prevent degradation of PEG and allow for cleansing of the colon without the use of adjunct laxatives, including stimulant laxatives such as bisacodyl. The disclosed methods are superior to the prior art in that they allow for higher tolerability, improved safety, lower volumes, and improved patient compliance.
US12239656B2	Nucleoporins as drug targets for anti-proliferative therapeutics Disclosed herein are methods of inhibiting nuclear pore complex assembly and inducing nuclear pore complex disassembly. Methods to screen for agents that inhibit nuclear pore assembly or induce nuclear pore complex disassembly are also disclosed.
US12239655B2	Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents Nucleoside compounds, which in some embodiments include an alkynyl substituent at the 4′-position, compositions and methods for treating or preventing HIV and other viral infections, particularly where the virus is present in macrophages, microglia, and primary myeloid cells, and eliminating and/or treating infection in patients infected by these viruses, are disclosed.
US12239654B2	Compounds and methods for treating neurological and cardiovascular conditions The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.
US12239653B2	Combination decitabine and cedazuridine solid oral dosage forms Embodiments of the present invention provide solid oral dosage forms that upon daily administration to a subject provide plasma levels of decitabine with a 5-day AUC for decitabine that is equivalent to the 5-day AUC for a daily IV dose of decitabine of 20 mg/m2 administered as a one hour (1 h) infusion. Also provided according to embodiments of the present invention are solid oral dosage forms wherein upon daily administration to a subject provides a pharmacodynamic effect that is equivalent to the pharmacodynamic effect for a daily intravenous dose of decitabine of 20 mg/m2 administered as a one hour (1 h) infusion. Also provided are methods of treatment using a solid oral dosage form according to an embodiment of the invention.
US12239652B2	Composition for preventing or treating muscular diseases, or for improving muscular functions, containing ganglioside The present invention relates to a composition for preventing or treating muscular diseases, or for improving muscular functions, containing gagnlioside. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating muscular diseases, a food composition for preventing or alleviating muscular diseases, or a cosmetic composition for preventing or alleviating muscular diseases, all of which comprise gagnlioside, which can increase the expression of proteins associated with muscle protein synthesis and muscle mass growth in muscle cells and inhibit the expression of enzymes involved in muscle protein degradation at the mRNA level.
US12239651B2	Treatment of hearing loss Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.
US12239650B2	Compounds for treating and preventing net associated complications The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of NETs in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating NET mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of NET mediated ailments. For example, the present invention relates to methods and uses of β-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.Na), in the therapy of a range of NET mediated ailments in subjects.
US12239648B2	KIF5B-RET fusion molecules and uses thereof Novel RET fusion molecules and uses are disclosed.
US12239646B2	Cancer diagnostic and treatment Bacterial species and the associated microbiome persist in tumors and metastases. Antibiotic treatment selectively reduces microbiome-induced tumor growth and can advantageously be included in treatment regimens. Accordingly, the present disclosure relates to, for example, the diagnosing cancer in a subject and providing identifying an effective treatment regimen for the subject.
US12239645B2	Targeted dosing for the treatment of complement mediated disorders The dosages and methods described herein provide desirable pharmacokinetic (PK) and pharmacodynamics (PD) characteristics which inhibit alternative pathway complement activity, for example at least 85% or more inhibition of AP activity in vivo at dosages from about 120 mg to 200 mg BID that provides a plasma level Ctrough at least about 65 ng/ml, which provides sufficient AP inhibition to reduce the risk of complement breakthrough. In addition, the dosage form described herein provides a significantly low Cmax, providing additional safety margin and better dosing flexibility.
US12239642B2	Bupropion dosage forms with reduced food and alcohol dosing effects This disclosure relates to dosage forms comprising bupropion hydrochloride, another salt form of bupropion, or the free base form of bupropion; dextromethorphan hydrobromide, another salt form of dextromethorphan, or the free base form of dextromethorphan, and a polymer. In some embodiments, the dosage form has no significant dose dumping of bupropion in the presence of ethanol in vitro. In some embodiments, the dosage form does not have a food effect for bupropion or dextromethorphan when taken with a high-fat meal in human subjects. Some embodiments include a method of treating a nervous system condition (such as depression, e.g., major depressive disorder, including treatment-resistant depression, agitation associated with Alzheimer's disease (or agitation associated with dementia of the Alzheimer's type), agitation associated with dementia, anxiety (or generalized anxiety disorder), neuropathic pain, or peripheral diabetic neuropathic pain) comprising, administering a dosage form described herein to a human being in need thereof.
US12239641B2	Methods of treating or preventing fibrosis in non-alcoholic fatty liver disease The present invention derives from the unexpected finding that ADRA2a antagonists decrease fibrosis in non-alcoholic fatty liver disease (NAFLD). Thus, by antagonising ADRA2a, many of the unwanted consequences or symptoms of NAFLD, may be reduced, such as impaired cognitive activity and fibrosis progression. The present invention utilises these findings to identify and provide ADRA2a antagonists that may be used in the treatment of fibrosis in NAFLD.
US12239638B2	Crystalline form of a 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compound The invention provides a crystalline hydrochloride salt of 4-[2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine. This invention also provides pharmaceutical compositions comprising the crystalline salt, processes and intermediates for preparing the crystalline salt, and methods of using the crystalline salt to treat diseases.
US12239637B2	Compositions and methods for treating neurological disorders The present invention generally relates to compositions and methods for treating a neurological disorder in a subject, the method including administering to the subject in need of such treatment a composition including a therapeutically effective amount of a CCR5 antagonist. The CCR5 antagonist may be, for example, maraviroc. The neurological disorder may be, for example, Alzheimer's disease, Parkinson's disease, dementia with Lewy bodies or multiple system atrophy.
US12239636B2	Combined sirolimus and nintedanib therapy for vascular lesions and hereditary hemorrhagic telangiectasia Methods and pharmaceutical compositions comprising one or more mTOR inhibitors such as sirolimus and one or more receptor tyrosine kinase inhibitors such as nintedanib are disclosed for treating vascular lesions and hereditary hemorrhagic telangiectasia.
US12239634B2	Methods of treating pruritus The present disclosure related to methods of treating pruritus in a subject by topically administering detomidine, or a pharmaceutically acceptable salt thereof, to the subject.
US12239633B2	Materials and methods for improving gastrointestinal function The subject invention provides therapeutic compositions, and uses thereof for the treatment or amelioration of injury to small intestine mucosa. In preferred embodiments, the composition comprises one or more nutrients and/or electrolytes that acquire or retain considerable absorptive capacity.
US12239629B2	Methods for the prophylaxis and treatment of COVID and COVID-19 The present invention recognizes that there is a need for the prophylaxis or treatment of COVID and COVID-19. A first aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using various pharmaceutical compositions. A second aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using combinations of antimalarial drugs and antiviral drugs. A third aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using nanoparticle formulations that include pharmaceutical compositions. A fourth aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using combinations of various pharmaceutical compositions. A fifth aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using a polio vaccine and pharmaceutical compositions.
US12239628B2	Cannabis composition The present invention relates to a method for treating a sleep disorder. Preferably, the invention relates to a method for treating a sleep disorder comprising the step of administering a pharmaceutical composition comprising a Cannabis extract and optionally one or more pharmaceutically acceptable carriers, diluents, adjuvants, excipients or any combination thereof, the Cannabis extract comprising a terpene fraction comprising limonene in an amount of at least about 5.4% by weight of the terpene fraction.
US12239627B2	Method of treating conditions related to the PGI2 receptor Provided in some embodiments are titration packages, kits, and methods of treating pulmonary arterial hypertension comprising prescribing and/or administering to a patient in need thereof 2-(((1r,4r)-4-(((4-chlorophenyl)(phenyl)carbamoyloxy)methyl)cyclohexyl)methoxy)acetic acid (Compound 1), or a pharmaceutically acceptable salt, hydrate, or solvate thereof, via a titration scheme that comprises the up-titration of Compound 1, or a pharmaceutically acceptable salt, hydrate, or solvate thereof, over a period of no more than about nine weeks until an optimized dose is administered.
US12239625B2	Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
US12239618B2	Histone acetyltransferase activators and compositions and uses thereof The invention provides pharmaceutical compositions and methods for treating cancer, neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein by administering a HAT modulator and a HDAC modulator to a subject.
US12239617B2	Mono- and di-amidine endo-exonuclease inhibitors and methods for inhibiting endo-exonuclease activity Compounds useful in inhibiting endo-exonuclease activity and treating cancer have the formula (I): wherein R3 is selected from the group consisting of loweralkyl, oxyalkyl, cycloalkyl, aryl, heteroaryl, heterocycloalkyl, aminoalkyl or a halogen; R4 is selected from the group consisting of H, loweralkyl, oxyalkyl, cycloalkyl, aryl, heteroaryl, heterocycloalkyl, aminoalkyl or a halogen; and wherein R5 is a loweralkyl; or formula (II): wherein R1 is selected from the group consisting of loweralkyl, oxyalkyl, cycloalkyl, aryl, heteroaryl, heterocycloalkyl, aminoalkyl or halogen; R2 is selected from the group consisting of H, loweralkyl, oxyalkyl, cycloalkyl, aryl, heteroaryl, heterocycloalkyl, aminoalkyl or halogen; and wherein R5 is a loweralkyl comprising a linear carbon chain of at least two carbons connecting the first “O” to the second “O”.
US12239616B2	Food supplement and composition comprising choline butyrate salt and/or butyrylcholine The present invention relates to the use of butyrylcholine in food and in particular in the treatment of intestinal disorders and in the stimulation of brain development. Furthermore, the invention provides for a food supplement and a pharmaceutical composition comprising butyrylcholine.
US12239615B2	Hydroxynorketamine for the use in the treatment of depression The present invention relates to hydroxynorketamine for the use in the treatment of depression. In particular, the present invention concerns hydroxynorketamine for use in the treatment of depression, wherein hydroxynorketamine is administered in form of at least one prodrug, and wherein the at least one prodrug is orally administered in a modified-release dosage form.
US12239614B2	Pharmacological prophylactics against stress-induced affective disorders in females Methods for prophylactically treating a stress-induced affective disorder or stress-induced psychopathology in a subject are provided. Also provided are methods for inducing and/or enhancing stress resilience in a subject. In certain embodiments, an effective amount of (R,S)-ketamine or (2R,6R)-hydroxynorketamine ((2R,6R)-HNK) is administered to a female or male subject prior to a stressor.
US12239611B2	Drug audit support device, drug audit support system, and drug audit method A drug inspection assisting apparatus for assisting an inspection of drugs collected by a drug collecting apparatus and/or by a manual operation, including: a plurality of drug inspection means, the drug inspection assisting apparatus being capable of implementing a plurality of drug inspection plans having different accuracies through selective implementation of the drug inspection means; an information acquiring means for acquiring first information and second information, the first information being information related to collection paths of drugs and/or devices involved in the collection of the drugs, the second information being information related to an operator who is involved in collection of drugs; and a plan selection means for selecting a certain drug inspection plan based on the first information and the second information, and the drug inspection plan selected by the plan selection means is implemented.
US12239608B2	Methods and apparatus for performing liquid medication bottle-splitting operations An apparatus for liquid medication bottle-splitting is provided. The apparatus includes: a first dispensing section comprising a funnel-shaped hollow body with a wide inlet opening tapering to a narrow outlet; a second dispensing section comprising a second funnel-shaped hollow body with a second wide inlet opening tapering to a second narrow outlet; and a crossover channel connecting the first dispensing section to the second dispensing section, the crossover channel including a crossover opening extending a length of the crossover channel, and the crossover channel being angled to evenly distribute a flow of liquid medication into at least a first split portion in the first dispensing section and a second split portion in the second dispensing section; the first dispensing section adapted to dispense the first split portion, and the second dispensing section adapted to dispense the second split portion.
US12239603B2	Mobilization tool personal care product container A container comprising a cavity for holding a personal care product, an opening for dispensing the personal care product and a working feature for activation of soft tissue, the working feature being a structural feature as found on a physical therapy soft tissue mobilization tool that is adapted to mobilize soft tissue.
US12239602B2	Vision training device A vision training device includes a main body, a lens unit, a drive motor, and a controller. The lens unit includes a plurality of lenses respectively having different diopter values and a lens holder that supports the lenses. The drive motor moves the lens holder so that one of the lenses of the lens unit is disposed on a line of sight axis. The controller controls the drive motor such that a test lens selected from the plurality of lenses is disposed on the line of sight axis and stores an accommodation time indicating a period of time in which the eye becomes in an accommodated state to the test lens.
US12239598B2	Walking assistance device A walking assistance device includes a belt-shaped lumbar region fixture, a first elastic string-like member, and a second elastic string-like member, wherein each of the first elastic string-like member and the second elastic string-like member is configured to be bifurcated near a knee of a leg, and the bifurcated parts of the first elastic string-like member and the second elastic string-like member are configured to be directly bound to each other at positions of an outer knee joint fissure gap and an inner knee joint fissure gap.
US12239594B2	Patient support with stand-up and sit features A bed is provided having a base frame, a patient support assembly connected to the base frame, and a tilt frame connected between the base frame and the patient support assembly. The tilt frame is rotatable adjacent the foot end of the bed to place the patient support assembly, including the head section, seat section and foot section thereof, in a generally vertical position to allow a patient to exit the bed in a standing orientation. The bed also has a foot board assembly connected to the foot section, the foot board assembly having a foot board separately moveable about a longitudinal axis of the bed toward the head end and the foot end of the bed.
US12239592B2	Patient transfer mattress Described is a patient transfer mattress for lifting and transferring patients. The patient transfer mattress can be used in a gentle and pressure ulcer preventative approach. Also described is a method for lifting and/or transferring a patient using a patient transfer mattress.
US12239590B2	Nursing bed system and nursing bed posture changing device A nursing bed system includes a nursing bed and a nursing bed posture changing device. The nursing bed posture changing device includes care recipient data acquiring circuitry that acquires care recipient data containing at least one of voice data of a care recipient who lies on the nursing bed, and image data obtained by imaging the care recipient, bed posture information generating circuitry that generates bed posture mode information according to a demand by the care recipient based on the care recipient data, and posture changing circuitry that changes the posture of the nursing bed based on the bed posture mode information.
US12239587B2	Wheelchair propulsion system An electric wheelchair propulsion system for a wheelchair. The propulsion system has a first and a second torque transfer hub rotatably mounted to a respective first and second drive wheel of the wheelchair, and an elongated axle tube arranged between the first and second hubs. First and second motors are arranged within the axle tube extending from opposing ends thereof. First and second drive axles are insertable into bores of the first and second hubs respectively, and are operatively connected to the first and second motors respectively. Means are provided to control the actuation of the motors. Actuation of the motors drives a rotation thereof, transferring a torque to the drive axles. The drive axles in turn transfer a torque to the hubs, thereby rotating the drive wheels.
US12239586B2	Mechanical wheelchair drive and wheelchair having such a mechanical wheelchair drive The invention relates to a mechanical wheelchair drive, comprising a rotatably mounted lever, a handle fastened to the lever, and a force transfer unit for transferring rotational motion of the lever to a wheelchair wheel, wherein the lever has a variable length and is guided along a closed guide of a guide plate, said guide deviating from the circular form, such that the length of the lever changes during the rotational motion.
US12239584B2	Interface moveably interconnecting surgical table and gantry An interface for moveably interconnecting a surgical table with a stationary gantry supporting a surgical robotic system is provided. The interface includes a collar portion, an actuator portion, and a locking portion. The collar portion is attached relative to a longitudinal cross-member of the surgical table via receipt of a portion of the longitudinal cross-member through the collar portion. The actuator portion is one of attached to the collar portion and attached to and/or supported by the gantry, and includes gearing operatively engaged to gearing attached to the longitudinal cross member. The locking portion is attached to and/or supported relative to the gantry, and includes a shoulder portion configured to contact an exterior surface of the collar portion, and at least one engagement portion moveable between a disengaged position and an engaged position. After the exterior surface is contacted to the shoulder portion, the locking portion can be moved from the disengaged position to the engaged position to maintain the position of the collar portion relative to the stationary gantry. And, after the collar portion is maintained in position relative to the stationary gantry, actuation of the actuator portion drives interaction of the gearing that moves portions of cross member into and out of the collar portion in a first linear direction and a second linear direction.
US12239583B1	Resuscitation chamber A resuscitation chamber apparatus for administering hyperbaric oxygen to a patient. More particularly, the present invention relates to a hyperbaric oxygen compatible critical care chamber apparatus preferably for use in emergency departments and/or prehospital ambulance management of patients. In a preferred embodiment of the present invention, the apparatus is a resuscitation monoplace hyperbaric chamber preferably used in critical care management of acutely ill or injured patients in prehospital emergency medical services (EMS) settings or in hospital emergency departments. The apparatus preferably allows a critical care shock or arrested patient to be pressurized preferably without compromise for application of best medical equipment, medications and human resuscitating intervention.
US12239582B2	Patient transport apparatus having powered drive system utilizing dual mode user input control Systems for facilitating movement of a patient transport apparatus are provided and include user input control device that includes a mode switch selectable between a longitudinal transport mode and a multidirectional mode and a driving assist device actuatable between at least one engaged state and a non-engaged state. The mode switch generates signals based on the selected mode and the driving assist device generates engaged or non-engaged signals which are received by a controller. The controller is configured to generate an output signal sent to a lift actuator, swivel actuator, and/or a powered drive system to assist a user in propelling the apparatus in a desired manner.
US12239581B2	Patient transport apparatus A patient transport apparatus (100, 10) which is configurable in at least three modes of operation, according to specific operational requirements. The apparatus (100, 10) comprises a patient support assembly 12 and at least a first and second wheel arrangement (14, 16). The patient support assembly 12 comprises a main portion 12.1, and a first and second portion (12.2, 12.3) extending from opposite sides of the main portion 12.1. The first and second portions (12.2, 12.3) are independently adjustable relative to the main portion 12.1. The first and second wheel arrangements (14, 16) are independently adjustable relative to the patient support assembly 12. The patient transport apparatus (100, 10) is configurable as a stretcher, as a chair (or wheelchair) and as a stair chair, by relative adjustment of the patient support assembly 12 and the first and second wheel arrangements (14, 16).
US12239579B2	Headworn supports with passive venting and removable lens Provided herein are examples of bead worn supports, such as eyewear, configured to provide passive venting by providing pathways between a lens and a frame and/or by providing a smooth anterior profile to allow a laminar flow of air on an anterior surface of the lens. The pathways through the frame and lens of the eyewear can be configured such that they do not provide a direct path to the eye of a wearer. The headworn supports provided hemin can provide venting while reducing or preventing unwanted light, particles, or other debris from contacting the eye of the user. The headworn supports can also be configured to exhibit excellent ballistic performance.
US12239575B2	Method and apparatus for shearing tissue at a target surgical site A surgical tool for shearing tissue at a target surgical site, the surgical tool comprising a cannula assembly with a distal end and a proximal end, a cannula opening into the lumen of the cannula at the distal end, a cutting device coupled to the distal end and within the cannula opening, and an axial ball joint coupled to the proximal end of the cannula assembly, that when rotated, causes the cutting device at the distal end to rotate about a longitudinal axis passing axially through the lumen of the cannula assembly, so as to shear a portion of tissue at a target surgical site.
US12239574B2	Aspirating cutter and method of use An ophthalmic surgical cutting apparatus for cutting biological material including a handle, an outer tube attached to the handle and having a closed tip, a port formed in a side wall of the outer tube with a cusp formed by two or more intersecting surfaces, and an inner tube slidable within the outer tube and having a longitudinal axis and an open tip. The inner tube is in fluid communication with the handle, and the cusp of the port and the open tip interface during a cutting motion to fracture and cut biological materials and direct cut materials radially inward into the port.
US12239573B2	Drug therapy delivery systems and methods Ocular medicament delivery devices are disclosed. In various embodiments, the ocular medicament delivery devices include multiple microporous layers arranged together to form a microporous body configured to meter dispensing of a medicament to surrounding tissues. In some embodiments, the ocular medicament delivery devices include one or more portions configured to resist tissue ingrowth, and one or more portions configured to permit tissue ingrowth. In some embodiments, the ocular medicament delivery devices deliver one or more medicaments useful in the treatment of glaucoma.

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