最新美国发明专利第2025-02-04期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US12215455B2	Diaphragm assembly and washing machine comprising same A washing machine including a body including a front frame; a tub provided inside the body; a dispenser to supply water to the tub; a diaphragm provided between the tub and the front frame, the diaphragm including a through hole formed on one side; a nozzle to spray the water toward an inside of the tub; and a supply hose formed to surround the nozzle while a portion of the nozzle is inside the through hole of the diaphragm, wherein a first side of the supply hose is formed to be coupled with the dispenser, and a second side of the supply hose is formed to extend toward an inside of the diaphragm through the through hole.
US12215451B2	Laundry appliance A laundry appliance includes a cabinet defining a front opening in a front panel. The front opening is defined by a lip having a curved edge. The lip defines a plurality of apertures spaced-apart around the front opening. A tub is disposed within the cabinet. The tub defines an access opening aligned with the front opening. A drum is disposed within the tub. A bellows assembly extends between the cabinet and the tub. The bellows assembly includes a projection coupled to the curved edge of the cabinet. A deflector has a rim and a chute wherein the chute extends toward the drum. The rim is configured to snap-fit over the projection of the bellows assembly. The rim includes a plurality of hooks where each hook is configured to extend through an aperture and interlock with the cabinet.
US12215450B2	Sewing machine provided with adjusting mechanism adjusting pressing force applied to workpiece In a sewing machine, a feed dog feeds a workpiece placed on a throat plate. A presser bar has a lower end portion on which a presser foot is mountable. A presser bar spring urges the presser bar downward. During a first prescribed period of time in which a top of the feed dog is above a top surface of the throat plate, an adjustment part of an adjusting mechanism is spaced apart from a restricting part of the adjusting mechanism to cause an urging force of the presser bar spring to be transmitted to the presser foot. During a second prescribed period of time in which the top of the feed dog is beneath the top surface of the throat plate, the adjustment part is in contact with the restricting part to prevent the urging force of the presser bar spring from being transmitted to the presser foot.
US12215448B2	Fiber assembly and method for producing fiber assembly A fiber assembly includes a support sheet, a warp yarn group in which warp yarns including a polymer material are arranged, and a weft yarn group in which weft yarns including a polymer material are arranged. A surface of the support sheet has been subjected to a release treatment. The warp yarn group and the weft yarn group are on the surface of the support sheet. The warp yarn group and the weft yarn group define contact portion regions and non-contact portion regions. In each of the contact portion regions, one of the warp yarns is integrated with one of the weft yarns. Each of the warp yarns and the weft yarns has a line width of 1 μm to 10 μm, inclusive. One of the contact portion regions has a fiber density which is higher than a fiber density of one of the non-contact portion regions.
US12215443B2	Yarn comprising a core and a sheath of fibers A yarn (1) having a core (2) and a sheath (3), preferably comprising staple fibers, said core comprising at least one polymeric core fiber (21), preferably a plurality of polymeric core fibers (21), wherein the amount of the core fibers (21) is at least 35% by weight of the total weight of the yarn (1) and said core (2) and said sheath (3) are spun together.
US12215442B2	Flame resistant fabric comprising a PTW fiber blend A yarn is disclosed, which includes a blend of: 33-75 wt. % of a flame resistant fiber having a limit of oxygen index of 43%, a thermal conductivity of 0.0063 watt/meter/K and a moisture regain of 12%; 10-40 wt. % of an aramid fiber; and up to 36% of a wearability enhancing fiber selected from the group consisting of wool, flame resistant rayon and lyocell, wherein the yarn is free of thermoplastics and is sufficiently flame resistant such that a fabric consisting of the yarn is effective to limit a body burn percentage resulting from 4 seconds of flame exposure to less than 35% as measured by ASTM F1930. Fabrics and garments including the inventive yarn are also disclosed.
US12215441B1	Method for preparing medium- and high-modulus large tow carbon fibers A method for preparing medium- and high-modulus large tow carbon fibers includes performing in-phase microwave heating on low-modulus large tow carbon fibers, and regulating and controlling a surface current density of the carbon fibers in the range of 60-330 A/m to rapidly reach graphitization temperature of the carbon fibers, thereby completing a uniform and rapid graphitization process. The medium- and high-modulus large tow carbon fibers obtained by the preparation method of the present application can have a tensile modulus reaching 300-600 GPa, and a tensile strength maintained to be 3.5-5.0 GPa, and a dispersion of the tensile modulus of the carbon fibers is less than 1.5%.
US12215440B2	Polymer filled polyolefin fiber The present invention relates to a polyolefin fiber comprising polymeric structures, wherein the polymeric structures individually comprise a polycondensate and a functionalized polymer, and the polyolefin fiber is a gel-spun high-performance polyethylene fiber that has a tenacity of at least 1 N/tex. The polymeric structures are immiscible with and dispersed in the polyethylene fiber. The gel-spun high-performance polyethylene fiber is a gel-spun ultrahigh molecular weight polyethylene fiber. The present invention further relates to a process for making the polyolefin fiber comprising the steps of: melt-mixing the polycondensate or a polycondensate containing at least one additive, the functionalized polymer, and optionally the thermoplastic polymer and/or the at least one additive, to form polymeric structures; mixing polyolefin powder, the polymeric structures and a solvent to form a mixture; and spinning and drawing the mixture obtained in step ii) to form the polyolefin fiber comprising the polymeric structures.
US12215437B2	Gradient single-crystal positive electrode material, and preparation method therefor and use thereof The present disclosure discloses a gradient single-crystal positive electrode material, which has a chemical formula of LiNixCoyA1-x-yO2@mLiaZbOc, wherein 0
US12215431B2	Processing and recycling method and product of ultrathin lithium foil Disclosed are a method for processing and recycling an ultrathin lithium foil and a product, which belongs to the field of lithium-ion batteries. According to the disclosure, a liquid-phase thinning agent is adopted to perform a contact reaction with a lithium metal, the fabricated ultrathin lithium foil has a thickness of 20 μm or less, the surface is flat, the thickness can be randomly regulated, and the uniformity is good. The method of the disclosure can also recycle a lithium-containing byproduct generated in the preparation process. When the ultrathin metal lithium foil prepared by the disclosure is used as a metal lithium negative electrode of a lithium battery, the energy density of the battery can be improved, and the battery manufacturing cost is reduced. The ultrathin metal lithium foil can also be used to supplement lithium for other types of electrode materials, thereby a broad application prospect is achieved.
US12215430B2	Method for increasing the surface roughness of a metal layer A method for increasing the surface roughness of a layer based on a metal having a catalytic power, includes fixing fluorine or chlorine on the surface of the metal based layer, by exposing the metal based layer to a plasma formed from a reactive gas containing fluorine or chlorine; exposing the surface of the metal based layer to a humid environment to produce an acid, by reaction of hydrogen from the humid environment with the fluorine or the chlorine fixed on the surface of the metal based layer, the acid reacting with the metal to form residues, the whole of the residues forming a pattern on the surface of the metal based layer, and etching the metal based layer through the residues, so as to transfer the pattern into the metal based layer.
US12215429B2	Method of sealing a surface and device therefor A method of sealing a surface is provided, the method comprising the steps of providing a metallic composition; providing a propellant; heating the metallic composition to above the melting point of the metallic composition to provide at least partially liquid metallic composition; accelerating the at least partially liquid metallic composition towards the surface by means of the propellant; and applying the at least partially liquid metallic composition to the surface.
US12215428B2	Coating systems including infiltration coatings and reactive phase spray formulation coatings A coating system configured to be applied to a thermal barrier coating of an article includes an infiltration coating configured to be applied to the thermal barrier coating. The infiltration coating infiltrates at least some pores of the thermal barrier coating. The infiltration coating decomposes within at least some pores of the thermal barrier coating to coat a portion of the at least some pores of the thermal barrier coating. The infiltration coating reduces a porosity of the thermal barrier coating. The coating system also includes a reactive phase spray formulation coat configured to be applied to the thermal barrier coating. The reactive phase spray formulation coating reacts with dust deposits on the thermal barrier coating.
US12215424B2	Metal resin composite, preparation method thereof, and electronic product housing having the same A metal resin composite includes a metal substrate, a metal layer formed on a surface of the metal substrate, and a resin layer formed on the metal layer. A plurality of microcracks are formed at a surface of the metal layer.
US12215421B2	Systems and methods for pulse width modulated dose control A substrate processing system for treating a substrate includes N manifolds, Y groups of injector assemblies, and a dose controller, where Y and N are integers greater than one. Each of the Y groups of injector assemblies includes N injector assemblies located in a processing chamber. Each of the N injector assemblies in each group of injector assemblies is in fluid communication with one of the N manifolds, respectively, and includes a valve including an inlet and an outlet. The dose controller is configured to control pulse widths output to the Y groups of injector assemblies to provide temporal dosing of the substrate.
US12215418B2	Apparatuses and method for oriented deposition Apparatuses and a method for gas phase deposition of high aspect ratio molecular structures, HARM-structures, are presented. The first aspect relates to an apparatus configured for oriented gas phase deposition of HARM-structures on a filter. The second aspect relates to an apparatus configured for oriented gas phase deposition of HARM-structures on a substrate. A system comprising multiple apparatuses according to the second aspect is also presented. Elements of the apparatuses are arranged to create a laminar flow of gas comprising HARM-structures in the deposition area, and to direct this flow at least partially parallel to the deposition area. Another aspect of the invention is a method for oriented deposition of HARM-structures, suitable for deposition both on a filter and a substrate.
US12215413B2	Mask assembly and manufacturing method thereof Provided by the present disclosure are a mask assembly and a manufacturing method thereof. In the mask assembly, a plurality of connecting posts are arranged at intervals on an outer periphery of a body of a metal plate, and a plurality of grooves matched with the connecting posts are arranged on a metal frame.
US12215411B2	Coated steel member, coated steel sheet, and methods for producing same A coated steel member includes: a steel sheet substrate containing, as a chemical composition, by mass %, C: 0.25% to 0.65%, Si: 0.10% to 1.00%, Mn: 0.30% to 1.00%, P: 0.050% or less, S: 0.0100% or less, N: 0.010% or less, Ti: 0.010% to 0.100%, B: 0.0005% to 0.0100%, Nb: 0.02% to 0.10%, Mo: 0.10% to 1.00%, Cu: 0.15% to 1.00%, and Ni: 0.05% to 0.25%; and a coating formed on a surface of the steel sheet substrate and containing Al and Fe. The maximum Cu content in a range from the surface to a depth of 5.0 μm is 150% or more of the Cu content of the steel sheet substrate.
US12215410B2	Grain oriented electrical steel sheet, forming method for insulation coating of grain oriented electrical steel sheet, and producing method for grain oriented electrical steel sheet A grain oriented electrical steel sheet includes a base steel sheet, an oxide layer, and a tension-insulation coating. When the iron oxide layer is analyzed by a fourier transform infrared spectroscopy, an absorbance A650 at 650 cm−1 and an absorbance A1250 at 1250 cm−1 satisfy 0.2≤A650/A1250≤5.0. Moreover, a magnetic flux density B8 in a rolling direction of the grain oriented electrical steel sheet is 1.90 T or more.
US12215409B2	High-strength and high-corrosion-resistant ternary magnesium alloy and preparation method thereof The present invention relates to a high-strength, high-corrosion resistance ternary magnesium alloy and a preparation method therefor, the magnesium alloy comprising the following element components by mass percentage: 8-12 wt % of Y, 0.6-3 wt % of Al and the remainder being Mg. The method comprises: (1) under a protective atmosphere, preparing a Mg—Y intermediate alloy, an aluminum ingot and a magnesium ingot into a magnesium alloy melt; (2) under a protective atmosphere, allowing the magnesium alloy melt to stand after stirring, then carrying out refining, degassing, and slag removal, allowing the magnesium alloy melt to stand again, then thermally insulating to obtain a magnesium alloy liquid; and (3) casting and molding the magnesium alloy liquid under a protective atmosphere, and forming a cast ingot; the three steps above ultimately obtain a high-strength, high-corrosion resistance ternary magnesium alloy.
US12215405B2	Hot-pressed member, cold-rolled steel sheet for hot pressing, and manufacturing methods therefor Provided is a hot-pressed member that combines both high strength of 1850 MPa or more in TS and excellent delayed fracture resistance. A hot-pressed member comprises: a predetermined chemical composition; a microstructure in which a prior austenite average grain size is 8 μm or less, a volume fraction of martensite is 95% or more, and a volume fraction of granular carbide of 0.1 μm or more in grain size is 0.10% to 4.0%; a Ni diffusion region of 2.0 μm or more in a depth direction in a surface layer; and a tensile strength of 1850 MPa or more.
US12215404B1	Carbide-free tempered martensitic steels and preparation methods thereof The embodiments of the present disclosure provide a carbide-free tempered martensitic steel and a preparation method thereof. The carbide-free tempered martensitic steel includes a martensite matrix without carbide and a retained austenite distributed between the martensite matrix obtained after tempering or partitioning. A size of retained austenite is submicron or nanoscale, a morphology of retained austenite includes at least one of sphere, block, or film, and a volume fraction of the retained austenite is in a range of 10%-40%.
US12215399B2	Non-oriented electrical steel sheet and method for producing same A non-oriented electrical steel sheet according to one embodiment of this invention includes a base metal steel sheet and a composite coating film composed of a Zn-containing phosphate and an organic resin, the composite coating film being formed on a surface of the base metal steel sheet. A molar ratio of Zn to all metal components in the composite coating film is 10 mol % or more, and after the non-oriented electrical steel sheet is boiled for 20 minutes in boiled distilled water, an amount of soluble Zn in the distilled water is 1.0 mg/m2 or more. The method for determining the amount of soluble Zn is in accordance with JIS K 0102: 2016 “Testing Methods for Industrial Wastewater”, 53.3 “ICP Emission Spectroscopy”.
US12215396B2	Iron-based alloy and method of manufacturing the same An iron-based alloy has excellent corrosion resistance and high strength and a method of manufacturing the iron-based alloy. The iron-based alloy includes Cr: 10 to 22 mass %, W: 1 to 12 mass %, and C: 0.1 to 2.3 mass %, with the remainder being unavoidable impurities and Fe, and is composed of a cast material having a structure composed mainly of austenite or a quenched material having a structure composed mainly of martensite and in which carbides are precipitated. The iron-based alloy may further include Cu: 0.5 to 6 mass % and/or Ni: 0.5 to 2.5 mass %, and may further include at least one of Al, Mo, and Si in an amount of 1 to 3 mass %.
US12215395B2	Method for recycling chromium oxide and forming chromium-alloy steel Disclosed are processes for recycling chromium oxide and producing chromium-alloy steel. Chromium oxide is reduced to metallic chromium and metallic chromium is mixed with steel to form chromium-alloy steel.
US12215393B2	Method and application for rapid and accurate chromosomal location of economic traits in laver The disclosure discloses a method and application for rapid and accurate chromosomal location of economic traits in laver, belonging to the fields of genomics and molecular breeding, wherein comprising the following steps: distinguishing the different genotype sectors by the color difference of pigment mutants, releasing monospores based on the asexual reproduction of single-genotype sectors, forming offspring CMD population; performing QTL-seq analysis on the extreme phenotype pools of offspring CMD population by SNP/InDel markers; and combining KASP and RNA-seq to predict the location of the genes of discrete traits or major QTL. The disclosure may solve the problem of difficulty in genetic analysis of various traits caused by the genotypic chimeric haploid characteristics.
US12215388B2	Theranostic tools for management of pancreatic cancer and its precursors The present invention concerns materials and methods for identifying and classifying pancreatic ductal adenocarcinoma (PDAC) precursors or intraductal papillary mucinous neoplasm (IPMN) using messenger RNAs, microRNAs, long non-coding RNAs, radiomic features, radiologic measures of abdominal/visceral obesity, and combinations thereof, as diagnostic markers for integration with clinical management and interventions for personalized care.
US12215382B2	Liver protective MARC variants and uses thereof Described herein are MARC variants that associate with a risk of liver diseases or a symptom(s) thereof, such as cirrhosis, or protection against such liver diseases or symptom(s) thereof. Also described herein are compositions and formulations that can be capable of modulating MARC in a subject and/or treatment of a liver disease or a symptom thereof.
US12215377B2	HIV or HCV detection with CRISPR-CAS13A The present disclosure relates to methods using CRISPR-Cas13a enzyme, complexed with HIV or HCV crRNAs to specifically and sensitively detect and quantify the presence of HIV or HCV RNA in a sample. These methods can be used to diagnose HIV or HCV infection, quantify the concentration of HIV or HCV RNA present in a sample, identify the presence of different HIV or HCV splice variants, subtypes, or mutations, and to monitor reactivation of HIV or HCV transcription.
US12215374B2	Biosensor with porous wicking layer The present invention relates to organic thin film sensors and the preparation and use thereof in sensing applications, and in particular in glucose sensing. The sensor is characterised by a layered structure comprising a porous wicking layer whose surface is configured to receive a liquid sample. An enzyme is disposed on or within the porous layer for facilitating the generation of a charge carrier from an analyte. A polymer layer in contact with the porous layer is connected to an ohmic conductor for applying a gate voltage to the polymer layer, the polymer layer being conductive to the charge carrier; and an organic semiconducting layer is connected to a source electrode and a drain electrode.
US12215370B2	Methods for detecting target analytes using synthetic biological circuits that modify glucose levels in a cell-free system Described are methods for generating a reporter molecule in response to a target analyte in a cell-free system. A synthetic biological circuit is used to modify the level of the reporter molecule in response to the presence of the target analyte. The reporter molecule may be glucose or another molecule readily detected using a device such as glucose monitor or other portable sensor. Also provided are kits comprising a cell-free system with a synthetic biological circuit that generates or consumes a reporter molecule in response to a target analyte.
US12215368B2	Engineered imine reductases and methods for the reductive amination of ketone and amine compounds The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered polypeptides, host cells capable of expressing the engineered polypeptides, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
US12215367B2	Lactase enzymes with improved properties Disclosed are peptides exhibiting betagalactosidase enzyme activity as well as dairy products comprising them and related methods for reducing the lactose content in compositions, such as dairy products.
US12215365B2	Cas variants for gene editing Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing enzymes or enzyme domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing enzymes or domains, are provided.
US12215362B2	Pharmaceutical composition for prevention or treatment of heart failure The present invention relates to a pharmaceutical composition for prevention and treatment of heart failure. Specifically, the present invention relates to a gene construct comprising a polynucleotide coding for SERCA2a protein or a fragment thereof and a polynucleotide coding for CCN5 protein or a fragment thereof, and a pharmaceutical composition comprising the same construct as an effective ingredient for preventing or treating heart failure. A pharmaceutical composition for prevention and treatment of heart failure according to the present invention is used in a method for co-expression of SERCA2a protein and CCN5 protein. Designed to exert a synergistic therapeutic effect through SERCA2a protein's function of preventing the loss of cardiomyocytes and increasing the activity of cardiomyocytes and CCN5 protein's function of suppressing the fibrosis of heart cells and tissues, the pharmaceutical composition can be useful for preventing or treating heart failure, which is a complex disorder induced by various etiological factors.
US12215359B2	Engineered glucose dehydrogenases and methods for the reductive amination of ketone and amine compounds The present application provides engineered glucose dehydrogenase polypeptides having imine reductase activity, polynucleotides encoding the engineered polypeptides, host cells capable of expressing the engineered polypeptides, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
US12215358B1	Coxsackievirus A6 strain CVA6-KM-J33 and use thereof Provided is a Coxsackievirus A6 (CVA6) strain CVA6-KM-J33 and use thereof, and belongs to the technical field of biomedicine. The present invention provides a CVA6 strain CVA6-KM-J33, which belongs to a CVA6 virus. In the present invention, the strain CVA6-KM-J33 is susceptible to KMB17 cells and can achieve a relatively high titer. The strain has strong virulence, high pathogenicity and lethality to suckling mice, and desirable immunogenicity, and is a highly effective virus strain for CVA6 vaccine development. This strain can be used for immunogenicity evaluation or protective evaluation of CVA6 vaccine to improve the accuracy and reproducibility of vaccine immunogenicity evaluation. This strain can also be used to prepare animal models of Coxsackievirus (CV) infection, and exhibits desirable application prospects.
US12215355B2	Stem cell derived islet differentiation Provided herein are methods of producing β cells and precursors thereof utilizing a Wnt signaling inhibitor or PKC activator, or both. Also provided herein are in vitro cultures comprising said cells, methods of treating a subject with a disease characterized by high blood sugar levels over a prolonged period of time by administering said cells, and devices for encapsulating said cells.
US12215345B2	Compositions and methods for the induction and tuning of gene expression Disclosed herein are compositions of transcription activator-like effectors transcription factors and methods of using the compositions for inducing gene expression of mammalian genes.
US12215343B2	Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
US12215335B2	Non-integrating DNA vectors for the genetic modification of cells The present invention relates to a polynucleotide comprising at least one promoter and an S/MAR element, wherein the S/MAR element is located downstream of the promoter in the 3′ UTR of the transcription unit and wherein the S/MAR element is flanked by a 5′ splice donor site and a 3′ splice acceptor site; the present invention further relates to a composition comprising the polynucleotide, and to the polynucleotide for use in medicine and for use in treating genetic disease.
US12215333B2	Pesticidal genes and methods of use Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptides having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the polypeptides, DNA constructs and vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the polypeptides. Polynucleotide sequences encoding the polypeptides can be used in DNA constructs or expression cassettes for transformation and expression in organisms of interest. The compositions and methods provided are useful for producing organisms with enhanced pest resistance or tolerance. Transgenic plants and seeds comprising a nucleotide sequence that encodes a pesticidal protein of the invention are also provided. Such plants are resistant to insects and other pests. Methods are provided for producing the various polypeptides disclosed herein, and for using those polypeptides for controlling or killing a pest. Methods and kits for detecting polypeptides of the invention in a sample are also included.
US12215330B2	Wheat with reduced lipoxygenase activity A series of independent human-induced non-transgenic mutations found at one or more of the Lpx genes of wheat; wheat plants having these mutations in one or more of their Lpx genes; and a method of creating and finding similar and/or additional mutations of Lpx by screening pooled and/or individual wheat plants. The wheat plants disclosed herein exhibit decreased lipoxygenase activity without having the inclusion of foreign nucleic acids in their genomes. Additionally, products produced from the wheat plants disclosed herein display increased oxidative stability and increased shelf life without having the inclusion of foreign nucleic acids in their genomes.
US12215324B2	Monocyte and macrophage binding aptamers and their application Provided herein are compositions comprising aptamers that specifically bind monocytes and/or macrophage and methods for their use. These aptamer compositions can be used in methods for isolating and/or enriching monocytes and/or macrophages or depleting cell populations of monocytes and/or macrophages. Further provided are methods of using the aptamers or cell populations generated using them in the methods disclosed herein for therapies and/or drug delivery.
US12215322B2	Treatment of liver disease with mitochondrial glycerol-3-phosphate acyltransferase (GPAM) inhibitors The present disclosure provides methods of treating subjects having liver disease, and methods of identifying subjects having an increased risk of developing liver disease.
US12215310B2	Means and methods to modulate probiotic potency of the yeast Saccharomyces boulardii Described herein are probiotics, more particularly [to] the probiotic yeast Saccharomyces boulardii. Even more particularly described herein are enhanced probiotic potency S. boulardii. Also described here are mutant alleles useful to develop yeast strains with enhanced production of acetic acid. In addition, described here is the use of such yeast strains for the production of dietary supplements or pharmaceutical compositions to improve gastrointestinal comfort.
US12215307B2	Culture device and methods for enumerating mold colonies A thin film culture device for enumerating mold colonies is provided. The device comprises water-resistant first and second substrates with a growth region disposed therebetween, a dry, cold water-soluble gelling agent disposed in the growth region, and an effective amount of a calcium-chelating compound disposed in the growth region. The effective amount of calcium-chelating compound is capable of reducing a rate of lateral enlargement of the colony-forming unit growing in the culture device relative to the rate of lateral enlargement of a colony of the same mold species growing in an otherwise identical culture device that does not contain the effective amount disposed in the growth region, wherein reducing the rate of lateral enlargement of the colony-forming unit does not substantially delay detection of the colony. A corresponding method is also provided.
US12215305B2	Tissue-processing container for automated processing of tissue, methods of use thereof, and systems comprising the same Tissue-processing containers are disclosed for facilitating multistep processing of tissue. Also disclosed are systems incorporating the tissue-processing containers that include shakers, incubators, controllers, and pumps. Multistep methods are disclosed for processing tissues using the tissue-processing containers. The tissue-processing containers are specially designed to achieve efficiencies in automated tissue processing, exposure of tissues to processing media, and multistep tissue processing protocols. The described tissue-processing containers comprise a cup-like cavity comprising a middle hole covered by a mesh screen, troughs for separate processing steps, and are stackable in a substantially airtight and substantially watertight manner. Tissues for processing using the described tissue-processing containers include nerve tissue. Also described herein is a transport housing for the transport of stacks of tissue-processing containers, and which may directly incubate those containers, or which may be placed inside a separate incubator for incubating the containers.
US12215302B1	Smectite clay-based fabric softener compositions with etheramine stabilizers The present disclosure relates generally to fabric softener compositions and processes for treating fabric using the same. The fabric softener compositions described herein include a smectite clay; a non-polymeric amine component selected from the group consisting of primary amines, secondary amines and tertiary amines; a water-soluble metal halide or sulfate; and optionally, an oil selected from the group consisting of a mineral oil and a vegetable oil.
US12215291B2	Stabilized medium chain triglyceride-based lubricant Household lubricant compositions containing medium chain triglycerides are non-toxic and biodegradable. The lubricant compositions are made using vegetable oil components and stabilized using alcohol, an antioxidant, and a metal chelator. The lubricant compositions offer safe and environmentally friendly alternatives to petroleum-based lubricants, yet have similar lubricity and are more stable than naturally sourced vegetable oils. The compositions also can be used to clean and coat surfaces, including food preparation surfaces, and to prevent corrosion. Still further uses include sterilization and sanitation of surfaces and as a skin conditioner and lubricant.
US12215286B2	Reactor for the hydrothermal treatment of biomass The disclosure concerns a reactor and a process for the hydrothermal treatment of an aqueous mixture, such as watery biomass. The reactor has an inlet for receiving the aqueous mixture, a tube-shaped reactor interior, which is inclined at an angle in the range of 1-45°; a first zone in the reactor interior with means for heating the aqueous mixture; a second zone in the reactor interior for keeping the aqueous mixture at the predetermined temperature; a third zone in the reactor interior for cooling the aqueous mixture; an outlet for discharging a hydrothermally treated aqueous mixture, and an outlet for discharging gas. The inlet and outlet for discharging gas are positioned at the top part of the reactor and the outlet for discharging aqueous mixture is at the bottom part of the reactor. The inclined nature of the reactor ensures that all gases are efficiently removed from the liquid effluent, and the CO2 formed during the process is used to improved efficacy of the hydrothermal treatment.
US12215275B2	Compositions for enhanced oil recovery Compositions and methods for increasing recovery, or flowback, of hydrocarbon compounds from hydrocarbon-containing subterranean oil formations. Concentrates include a sulfonated and/or a sulfated surfactant, an alkoxylated alcohol surfactant, a coupling agent, a hydrotrope, an additional surfactant, and water. Injectate compositions for oil recovery include the concentrate and a water source such as a produced water and/or seawater. Inclusion of particular hydrotropes such as sodium xylene sulfonate and/or potassium toluene phosphate in the compositions provides higher yields of hydrocarbons recovered. Larger amounts of hydrotrope result in an increase in injectate interfacial tension, but also result, as judged by decreased turbidity, in improved compatibility of the surfactant system in injectates made with water sources comprising salts.
US12215274B1	Resin slurry plugging system suitable for fractured-vuggy formation and preparation and use thereof A resin slurry for a fractured-vuggy formation and the preparation and use thereof, which belong to the field of drilling fluid lost circulation control. The resin slurry plugging system is composed of the following raw materials in mass percentage: 20%-40% of composite resin plugging agent, 0.5%-5.0% of consolidating agent, 0.5%-5.0% of flow pattern regulator, 0.3%-1.2% of cross-linking agent, 0.3%-1.2% of retarder, 3%-12% of filling agent, and the balance of water. The plugging system has a certain fluidity under low-temperature conditions, is easy to be injected into the formation, and can fill a lose channel of a fractured-vuggy reservoir. The consolidating time of the plugging system is controllable, and the construction conditions are safe. The plugging system forms a three-dimensional cross-linked network structure consolidation after cross-linking and consolidating under high-temperature conditions of the formation.
US12215272B2	Heat transfer fluids and corrosion inhibitor formulations for use thereof Heat transfer fluid concentrates include: (a) a freezing point depressant; and (b) a non-ionic surfactant comprising (i) a corrosion inhibitor for copper and copper alloys and (ii) a polyalkylene glycol. A conductivity of the heat transfer fluid concentrate is less than or equal to about 100 S/cm. Ready-to-use heat transfer fluids and methods for preventing corrosion in heat transfer systems are described.
US12215265B2	Green-emitting phosphors and devices thereof Green-emitting phosphors are useful in devices including an LED light source radiationally coupled and/or optically coupled to the phosphors, which are selected from [Ba1−a−bSraCab]x[Mg,Zn]y(UO2)z([P,V]O4)2(x+y+z)/3, where 0≤a≤1, 0≤b≤1, 0.75≤x≤1.25, 0.75≤y≤1.25, 0.75≤z≤1.25; and [Ba,Sr,Ca,Mg,Zn]p(UO2)q[P,V]rO(2p+2q+5r)/2, where 2.5≤p≤3.5, 1.75≤q≤2.25, 3.5≤r≤4.5.
US12215264B2	Multichroic glasses A glass having from greater than or equal to about 0.1 mol. % to less than or equal to about 20 mol. % Ho2O3, and one or more chromophores selected from V, Cr, Mn, Fe, Co, Ni, Se, Pr, Nd, Er, Yb, and combinations thereof. The amount of Ho2O3 (mol. %) is greater than or equal to 0.7(CeO2 (mol. %)+Pr2O3 (mol. %)+Er2O3 (mol. %)). The glass can include one or more fluorescent ions selected from Cu, Sn, Ce, Eu, Tb, Tm, and combinations thereof in addition to, or in place of the chromophores. The glass can also include multiple fluorescent ions.
US12215259B2	Multilayer object and release agent composition The invention provides a laminate having a first substrate formed of a semiconductor substrate; a second substrate formed of a light-transmissive support substrate; and an adhesive layer and a release layer disposed between the first substrate and the second substrate, characterized in that the release layer is a film formed from a releasing agent composition containing a polynuclear phenol derivative represented by formula (P) (wherein Ar represents an arylene group), a cross-linking agent, and at least one of an acid generator and an acid.
US12215258B2	Pressure-sensitive adhesive sheet and use thereof Provided is a PSA sheet having a PSA layer. The PSA layer has a multilayer structure comprising a layer A forming one face of the PSA layer and a layer B placed on the backside of the layer A. The layer B is a photo-crosslinkable PSA layer comprising a photo-crosslinkable polymer.
US12215257B2	Composition for self-suction adhering foam sheet and self-suction adhering foam laminate sheet Provided is a composition for a self-suction adhering foam sheet that can be used to obtain a self-suction adhering foam laminate sheet that has excellent air releasability while also inhibiting formation of resin residue on metal after weathering. The composition for a self-suction adhering foam sheet contains a polymer including an unsaturated carboxylic acid monomer unit in a proportion of not less than 0.1 mass % and not more than 20 mass %, a cross-linker, and 1.5 parts by mass or more of a higher fatty acid salt per 100 parts by mass of the polymer.
US12215250B2	Adhesive composition and heat-fusible member using same An adhesive composition having high room-temperature peel strength, high hot peel strength, and excellent adhesion, as well as excellent electrolyte resistance even when used for packaging materials for lithium ion batteries is provided, which contains an organic solvent, a polyolefin (A) that has an acidic group and/or an acid anhydride group and is soluble in the organic solvent, and an isocyanate compound, wherein the isocyanate compound comprises (B) a diisocyanate compound having a C4-7 hydrocarbon group and/or a derivative thereof, and (C) a diisocyanate compound having a C8-14 hydrocarbon group and/or a derivative thereof; and a heat-fusible member using the adhesive composition is also provided.
US12215246B2	Composition comprising a light-weight filler The present invention relates to compositions containing at least one reactive binder, at least one curing agent and/or accelerator, at least one thermally activatable blowing agent and at least one light-weight filler, wherein at least one expanded particle of at least one glass-rich volcanic rock with a closed outer shell is contained as a light-weight filler. The invention also relates to a method for stiffening and/or reinforcing components with thin-walled structures with a corresponding composition as well as to correspondingly produced components.
US12215242B2	UV-VIS radiation curable security inks for producing dichroic security features The present invention provides a UV-Vis radiation curable security ink for producing a security feature for securing value documents, wherein said security feature exhibits a blue color upon viewing in transmitted light and a metallic yellow color upon viewing in incident light. The UV-Vis radiation curable security ink comprises a cationically curable or a hybrid curable ink vehicle, and silver nanoplatelets bearing a surface stabilizing agent of general formula (I) wherein the residue RA is a C2-C4alkyl group substituted with a hydroxy group; the residue RB is selected from a C1-C4alkyl group, and a C2-C4alkyl group substituted with a hydroxy group; and Cat+ is an ammonium cation of general formula +NH2RCRD, wherein the residue RC is a C2-C4alkyl group substituted with a hydroxy group; and the residue RD is selected from a C1-C4alkyl group, and a C2-C4alkyl group substituted with a hydroxy group.
US12215240B2	Aqueous ink, ink cartridge and ink jet recording method Provided is an aqueous ink capable of recording an image having a good hue as a magenta ink. The aqueous ink is an aqueous ink for ink jet including a first coloring material and a second coloring material. The first coloring material is a compound represented by general formula (1), and the second coloring material is a compound represented by general formula (2). A proportion (% by mass) of a content of the second coloring material to a total content of the first coloring material and the second coloring material in the aqueous ink is 0.60% by mass or more.
US12215239B2	Ink composition, ink set, and image recording method An ink composition is an ink composition including titanium dioxide particles, metal oxide particles, a dispersant, and water, in which an average particle diameter of the titanium dioxide particles is 100 nm or greater, an average particle diameter of the metal oxide particles is smaller than the average particle diameter of the titanium dioxide particles, and the metal oxide particles are oxide particles of at least one metal selected from the group consisting of zirconium, aluminum, silicon, zinc, and iron.
US12215238B2	Clear ink, printing method, and inkjet printing apparatus A clear ink includes resin particles, water, and a compound represented by General Formula (1) below. The resin particles have a volume average particle diameter of 50 nm or less. A dried film of the clear ink has glass transition temperatures (Tg) at 50 degrees Celsius or higher and at lower than 0 degrees Celsius. In the General Formula (1), R1 represents an alkyl group having 1 or more but 4 or less carbon atoms.
US12215237B2	High opacity white ink The present invention provides a high opacity solvent based white ink or coating composition that provides high levels of opacity to substrates used for packaging materials that are printed via flexography or gravure. The ink or coating composition contains up to 75 wt % titanium dioxide, while still having a viscosity suitable for flexographic and gravure printing methods.
US12215235B2	Composite member Provided is a composite member, including: an inorganic layer that contains an inorganic substance containing at least one of a metal oxide or a metal oxide hydroxide. The composite member includes a resin layer that is provided on a surface of the inorganic layer and contains a resin and inorganic particles that are dispersed in the resin and some of which adhere directly to the inorganic substance of the inorganic layer. A porosity in a cross section of the inorganic layer is 20% or less, and a peak derived from a hydroxyl group is detected for the inorganic layer when measurement is performed using infrared spectroscopy or X-ray diffraction.
US12215234B2	Process for the purification of methylene blue The present application provides method for producing methylene blue that includes the steps of providing a reaction mixture having one or more methylene blue intermediates; precipitating metal from the reaction mixture; and producing therefrom crude methylene blue. The crude may further be purified, resulting in methylene compounds having low impurities, preferably having a purity greater than about 97%, having Azure B impurity no greater than 2.5%, and/or a total metal content no greater than 77 ppm. Formulations containing such compounds are also provided.
US12215233B2	Polydiorganosiloxane compositions and methods for use thereof in forming wood plastic composites A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.
US12215232B2	Asphalt compositions including recycled polymer and epoxy-functionalized ethylene copolymer The present disclosure provides embodiments of an asphalt composition and methods of making that may include asphalt binder; a recycled polymer component; an epoxy-functionalized ethylene copolymer, the epoxy-functionalized ethylene copolymer having the formula E/X/Y/Z. E may be a copolymer unit —(CH2CH2)— derived from ethylene; X may be a copolymer unit —(CH2CR1R2)—, where R1 is hydrogen, methyl, or ethyl, and R2 is carboalkoxy, acyloxy, or alkoxy of 1 to 10 carbon atoms, present in from 0 to about 40 weight % of the copolymer; Y may be a copolymer unit —(CH2CR3R4)—, where R3 is hydrogen or methyl and R4 is carboglycidoxy or glycidoxy present in from 0 to about 25 weight % of the copolymer; Z may be a copolymer derived from comonomers including carbon monoxide, sulfur dioxide, acrylonitrile, or other monomers, present from 0 to about 10 weight % of the copolymer.
US12215230B2	Tire The present invention provides a tire having a good balance of fuel efficiency, chipping resistance, and steering stability.
US12215229B2	Lip seal Lubricity of a lip seal material using hydrogenated nitrile rubber is improved. A rubber-like elastic lip seal which is fixed to a housing and slides with a shaft that rotates relatively with the housing, wherein the lip seal includes a rubber-like elastic body containing hydrogenated nitrile rubber, EPDM or fluoro rubber, a reinforcing filler material, and a non-reinforcing filler material having an aspect ratio in a range of 1 or more and 30 or less, and the lip seal contains 1 part by weight or more and 150 parts by weight or less of the reinforcing filler material and 5 parts by weight or more and 90 parts by weight or less the non-reinforcing filler material per 100 parts by weight of the rubber-like elastic body.
US12215223B2	Crystallizable resins This disclosure provides polymeric materials comprising polymer crystals, methods and resins for making the same, and objects and appliances made from said polymeric materials. Polymeric materials having polymer crystals provide favorable properties, such as enhanced durability and rigidity. This disclosure also provides polymeric materials comprising a crystalline phase comprising at least one polymer crystal, as well as an amorphous phase comprising at least one amorphous polymer. The crystalline phase can confer rigidity to the polymeric material, while the amorphous phase can confer elasticity and flexibility.
US12215218B2	Hitting sound reducing material and thermoplastic resin composition A hitting sound reducing material made of a (meth)acrylic acid ester polymer (B) comprising: a polymer (b1) comprising a structural unit derived from an acrylic ester compound and a structural unit derived from a methacrylic ester compound, and having a glass transition temperature of −15° C. to +5° C.; and a polymer (b2) comprising at least one selected from the group consisting of a structural unit derived from a methacrylic acid ester compound, a structural unit derived from an aromatic vinyl compound, and a structural unit derived from a vinyl cyanide compound, wherein the polymer (b1) has a temperature (peak temperature) indicating a peak value of a main dispersion of tan δ of −5° C. to +20° C., and a peak intensity, which is a peak value of the intensity, of 2.055 or more.
US12215217B2	Composition for acoustic member and acoustic member A composition for an acoustic member includes a non-diene butyl rubber, and a liquid polymer having a molecular weight of 1,000 to 120,000. A difference in an SP value between the liquid polymer and the butyl rubber is within ±0.5.
US12215216B2	Polypropylene composition for interior automotive applications A composition suitable for automotive application obtainable by blending at least components (A), (B) and (C): (A) 15 wt.-% to 50 wt.-%, preferably 17 to 47 wt.-%, more preferably 18 to 45 wt.-% of a mixed-plastics polypropylene blend; (B) 10 wt.-% to 60 wt.-%, preferably 15 to 55 wt.-%, more preferably 17 to 52 wt.-% of a first heterophasic propylene copolymer; and (C) 5 wt.-% to 25 wt.-%, preferably 7 to 22 wt.-%, more preferably 8 to 20 wt.-% of an inorganic filler.
US12215215B2	Stabilizer compositions and methods for using same for protecting polymeric organic materials from UV light and thermal degradation Stabilizer compositions having a stabilizing amount of at least one co-active agent; an ultraviolet light absorber chosen from an ortho-hydroxy benzophenone, and/or an ortho-hydroxyphenyl benzotriazole; and a hindered amine light stabilizer, are provided herein, along with masterbatch concentrates containing same, and processes for using same for stabilizing polymeric organic materials to protect against light and thermal degradation due to exposure to UV irradiation.
US12215214B2	Low density polyethylene with enhanced adhesion-to-aluminum foil by blending-in acid copolymer resins The polymer blend includes at least 90% by weight low density polyethylene (LDPE) polymer and from 1% to 10% by weight acid copolymer based on the total weight of the polymer blend. In the polymer blend, the LDPE polymer has a melt index (I? 2 #191) from 2 g/10 min to 8 g/10 min as determined in accordance with ASTM D1238, and a molecular weight distribution from 5 to 10.5. In the polymer blend, the acid copolymer is a polymerized reaction product of: at least 60% by weight ethylene, based on the total weight of the monomers present in the ethylene acid copolymer; from 1% to 20% by weight monocarboxylic acid monomer, based on the total weight of the monomers present in the ethylene acid copolymer; and from 0 to 20% by weight alkyl acrylate monomer, based on the total weight of the monomers present in the ethylene acid copolymer.
US12215212B2	Aqueous resin crosslinking agent, aqueous resin crosslinking agent-containing liquid, and aqueous resin composition A waterborne resin crosslinking agent containing a predetermined polycarbodiimide compound (A) having an oxyalkylene group, a predetermined polycarbodiimide compound (B), and a surfactant (C), each polycarbodiimide compound has a structure in which an isocyanate group is capped with a predetermined end-capping compound at each of both terminals, a total content of the oxyalkylene group in (A) is 15% by mass or more, a total content of the oxyalkylene group in (A) and (B) based on a total amount of (A) and (B) is 10% by mass or less, and a content of (C) is 0.1 to 20 parts by mass based on a total content of (A) and (B) of 100 parts by mass.
US12215209B2	Solvent blends for olefin shrink film seaming, shrink labels formed with said solvent blends and methods of providing seams with said solvent blends A solvent blend useable for tackifying a surface of a plastic film includes a terpene based solvent and one or more of a solvent from the group consisting of a straight chain alkane, a branched chain alkane, a cyclic alkane, a substituted cyclic alkane, a straight chain ether, a branched chain ether, a cyclic ether, a substituted cyclic ether, a cyclic diether, a substituted cyclic diether, a straight chain ketone, a branched chain ketone, a cyclic ketone, a substituted cyclic ketone, a straight chain ester, and a branched chain ester.
US12215205B2	Vulcanization composition for reducing allergenic potential and elastomeric articles formed therewith An elastomeric article having a rubber component comprising polyisoprene and an aldehyde aniline condensate, the elastomeric article having less than 1 ppm diisopropyl xanthogen polysulfide residue.
US12215197B2	Crystalline, two dimensional polymers and a process for the preparation thereof The present invention relates to a crystalline, two dimensional polymer of Formula I and a process for the preparation thereof.
US12215195B1	Cross-linkable thermoplastics, and processes of making and using same The invention relates to cross-linkable thermoplastics, processes of making such cross-linkable thermoplastics and products comprising such cross-linkable thermoplastics. Such cross-linkable thermoplastics provide articles made by the additive manufacturing (AM) process with increased strength, the desired in use temperature stability and the desired thermo-oxidative stability.
US12215191B2	Polyalkylene ether glycol composition and method for producing the same A polyalkylene ether glycol composition containing a nitrogen-containing compound. The nitrogen-containing compound constitutes 0.2 to 40 mass ppm of the polyalkylene ether glycol in terms of nitrogen atoms, and the nitrogen-containing compound has a boiling point in a range of −40° C. to 120° C. at atmospheric pressure. An elastic stretchable fiber, a polyurethane, a synthetic leather, or a thermoplastic elastomer containing the polyalkylene ether glycol composition.
US12215190B2	Squaric acid-based polymers, their manufacturing processes and their uses Squaric acid-based polymers and their use in electrode materials and/or electrolyte compositions, as well as their production processes are described herein. Also described are electrode materials, electrodes, electrolyte compositions, electrochemical cells, electrochemical accumulators, and optoelectronic devices comprising the polymers and their uses.
US12215187B2	Continuous manufacturing of polyol A method of continuously producing a polyol includes: (i) feeding a solid catalyst into a continuous stirred tank reactor (CSTR); (ii) contacting a reaction mixture comprising one or more epoxides and carbon dioxide with the solid catalyst and a chain transfer agent comprising a plurality of sites capable of initiating copolymerization of epoxides and carbon dioxide in the CSTR; (iii) allowing polymerization reaction to proceed until a desired molecular weight polyol has formed; and (iv) terminating the polymerization reaction.
US12215182B2	Urethane prepolymer, adhesive, skin patch material, adhesive tape, wearable device, and wearable device kit Provided are a urethane prepolymer from which is obtained an adhesive which has excellent moisture permeability and which attains both low adhesion to skin and high adhesion to a base material, an adhesive, a skin patch material, an adhesive tape, a wearable device, and a wearable device kit. The urethane prepolymer is a hydroxyl-group-terminated urethane prepolymer obtained by reacting an oxyalkylene polymer A having an average number of hydroxyl groups per molecule of 2.1 to 3, an oxyalkylene polymer B in which the number of hydroxyl groups per molecule is 1, and a diisocyanate compound, the number-average molecular weight of the oxyalkylene polymer B being 5000 or greater, and the content of ethylene oxide units in the hydroxyl-group-terminated urethane prepolymer being more than 10 mass %.
US12215180B2	Mixture curable to provide a material for thermally insulating a substrate useable subsea A mixture curable in the presence of a metallic catalyst to provide a material for thermally insulating a substrate useable subsea. The mixture comprises from 55 to 99% by weight of a norbornene monomer and a water insoluble polymer filler. The water insoluble polymer filler comprises polystyrene or polypropylene, or derivatives thereof.
US12215175B2	UV curable water based polyelectrolyte composition and method for producing polyelectrolyte film using the composition The present invention relates to a UV curable water-based polyelectrolyte composition and a method for producing a polyelectrolyte film using the same, which provides a polyelectrolyte composition comprising: at least one polyelectrolyte selected from Formulas 1 to 3; an acrylate-based material; a cross-linker; a photoinitiator; and a solvent.
US12215174B2	Compositions of hydroxypropyl-β-cyclodextrin and methods of purifying the same The present disclosure relates to compositions comprising mixtures of hydroxypropyl-β-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-β-cyclodextrins.
US12215171B2	Rabbit antibodies to human immunoglobulins G This disclosure anti-human IgG antibodies and antigen-binding portions thereof derived from rabbits and methods of using these antibodies and portions.
US12215170B2	Anti-TMPRSS6 antibodies and uses thereof Antibodies and antigen-binding fragments thereof that bind type II transmembrane serine protease 6 (TMPRSS6) on the surface of a cell and increase hepcidin expression, and methods for treating disorders of iron metabolism using anti TMPRSS6 antibodies and fragments, are provided.
US12215168B2	Anti-A2AP antibodies and uses thereof The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.
US12215160B2	Treatment of patients having c-met exon 14 skipping mutations The present invention relates to treatment of subjects having a cancer that is positive for c-Met exon 14 skipping mutations.
US12215159B2	Anti-CD161 antibodies and uses thereof The invention relates generally to anti-CD161 antibodies, pharmaceutical compositions comprising such antibodies, and methods of using such antibodies for treating disorders associated with or mediated by CD161, for example, certain cancers. In addition, the invention also relates to expression vectors and host cells for making these antibodies.
US12215155B2	Antibodies binding to CD3 and CD19 The present invention generally relates to antibodies that bind to CD3 and CD19, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
US12215153B1	Anti-receptor expressed on lymphoid tissues (RELT) recombinant monoclonal antibody and preparation method and use thereof The present disclosure relates to the technical field of chemoimmunology, and in particular to an anti-receptor expressed on lymphoid tissues (RELT) recombinant monoclonal antibody and a preparation method and use thereof. The anti-RELT recombinant monoclonal antibody includes a heavy chain variable region and a light chain variable region, where the amino acid sequence of the heavy chain variable region is set forth in SEQ ID NO: 4; the amino acid sequence of the light chain variable region is set forth in SEQ ID NO: 5; and the anti-RELT recombinant monoclonal antibody has a biological activity of neutralizing a function of RELT. In addition, because the anti-RELT recombinant monoclonal antibody has the biological activity of neutralizing the function of RELT, the anti-RELT recombinant monoclonal antibody can specifically recognize and detect the expression of RELT in different tissues and cells.
US12215152B2	Humanized anti-human CD19 antibodies and methods of use Herein is reported an antibody that specifically hinds to human CD 19, wherein the antibody comprises (a) HVR-H1 comprising the amino acid sequence of SEQ ID NO: 03, (b) HVR-H2 comprising the amino acid sequence of SEQ ID NO: 11, (c) HVR-H3 comprising the amino acid sequence of SEQ ID NO: 05, (d) HVR-L1 comprising the amino acid sequence of SEQ ID NO: 20 or 28, (e) HVR-L2 comprising the amino acid sequence of SEQ ID NO: 07, and (f) HVR-L3 comprising the amino acid sequence of SEQ ID NO: 08, as well as methods of using the same.
US12215151B2	Methods of treating cancer using antibodies and molecules that immunospecifically bind to BTN1A1 Provided herein are methods for treating cancer using molecules having an antigen binding fragment that immunospecifically binds to BTN1A1, such as anti-BTN1A1 antibodies. These molecules include those having an antigen binding fragment that immunospecifically binds to glycosylated BTN1A1, such as anti-glycosylated BTN1A1 antibodies. Also included are molecules having an antigen binding fragment that immunospecifically bind to BTN1A1 dimers, such as anti-BTN1A1 dimer antibodies. Also provided are methods for treating anti-PD-1 therapy or anti-PD-L1 therapy resistant or refractory cancers.
US12215149B2	Anti-MS4A6A antibodies and methods of use thereof The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a MS4A6A polypeptide, e g., a mammalian MS4A6A or human MS4A6A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
US12215148B2	Antigen binding molecule formats Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.
US12215147B2	Methods of selecting, based on polymorphisms, an inflammatory bowel disease subject for treatment with an anti-TL1A antibody Provided are methods, systems, and kits for selecting a patient for treatment with a therapeutic agent based on a presence of a genotype associated with a positive therapeutic response to the therapeutic agent. The therapeutic agent, in some embodiments, is an inhibitor of TL1A activity or expression, such as for example, an anti-TL1A antibody.
US12215146B2	Antibody variants The present invention relates to antibodies which bind to TNFα and exhibit modified FcRn-binding. The antibodies of the invention have good effector functions and/or pharmacokinetic properties.
US12215145B2	Treatment of headache using anti-CGRP antibodies Methods for immediate relief of migraine or headache are provided comprising the administration of an anti-CGRP antagonist antibody to a patient in need thereof.
US12215144B2	Acute treatment and rapid treatment of headache using anti-CGRP antibodies Methods for rapid treatment of chronic migraine are provided. Exemplary methods provide relief from migraine within 24 hours of administration. Also provided are methods for acute treatment of migraine. Exemplary methods comprise administration of an anti-CGRP antagonist antibody to a patient in need thereof.
US12215139B2	Preparation method and application of high-purity plant-derived recombinant human serum albumin The present invention provides a method for preparing high-purity recombinant human serum albumin and its applications as a drug and biopharmaceutical excipient. The recombinant human serum albumin from Oryza sativa (OsrHSA) prepared by the present invention can be replaced of plasma-derived human serum albumin for uses of the clinic and pharmaceutical excipients in term of safe and effective. Furthermore, it can effectively maintain the biological activity of biological macromolecules.
US12215138B2	Compositions and methods for internalizing enzymes Compositions and methods for treating enzyme-deficiency diseases are disclosed. Multidomain therapeutic proteins containing an internalization effector binding domain and a lysosomal replacement enzyme activity are disclosed. The multidomain therapeutic proteins are capable of entering cells, segregating to the lysosome, and delivering the replacement enzyme activity to the lysosome.
US12215136B2	Exosome for stimulating T cell and pharmaceutical use thereof The present invention relates to an exosome for stimulating T cells and the pharmaceutical use thereof. Immune exosomes secreted from artificial antigen-presenting cells which express HLA, CD32, and co-stimulatory molecules CD32, CD80, CD83, and 4-1BBL are used to stimulate naive CD8+ T cells whereby preventive and therapeutic effects on tumors, pathogen infections, or autoimmune diseases can be provided.
US12215132B2	Methods, compositions and uses thereof for reversing sarcopenia Exemplary methods, compositions and uses thereof can be provided for preventing, reducing and/or treating loss of muscle function. In particular, e.g., it is possible to administer to a subject a pharmaceutical composition comprising a therapeutically effective amount of an agent that enhances Interleukin-6 (IL) release during exercise, and optionally a pharmaceutically acceptable carrier or excipient.
US12215129B2	Antibacterial cyclopeptides targeting acinetobacter and other gram-negative pathogens In one aspect, the invention relates to cyclopeptides and methods of using the disclosed cyclopeptides to treat bacterial infections due to, for example, Gram-negative pathogens. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US12215125B2	Method for spray drying D-tagatose A D-tagatose spray-drying feed formulation is a mixture of D-tagatose and a functional excipient co-dissolved in a solvent to produce a excipient/D-tagatose composite having a glass transition temperature of greater than 30° C. A method of spray-drying D-tagatose includes the steps of (a) preparing the D-tagatose spray-drying formulation, (b) atomizing the D-tagatose spray-drying formulation in a drying chamber containing a hot inert processing gas and evaporating droplets to produce solid particles of excipient/D-tagatose composite and (c) separating and collecting the solid particles of excipient/D-tagatose composite from the processing gas.
US12215119B2	Method for obtaining low molecular weight lignin The invention relates to obtaining lignin preparations of desirable molecular size and properties. It describes a method of de-polymerizing lignin of high molecular weight into low molecular weight lignin. More in particular, the invention provides a method for producing lignin with a low molecular weight wherein high molecular weight lignin is contacted with an alkaline laccase at alkaline pH in a reaction vessel and wherein the lignin with a molecular weight below 2 kDa is selectively removed from the reaction vessel during the reaction.
US12215118B2	Quinone methide analog signal amplification Disclosed herein are novel quinone methide analog precursors and embodiments of a method and a kit of using the same for detecting one or more targets in a biological sample. The method of detection comprises contacting the sample with a detection probe, then contacting the sample with a labeling conjugate that comprises an enzyme. The enzyme interacts with a quinone methide analog precursor comprising a detectable label, forming a reactive quinone methide analog, which binds to the biological sample proximally to or directly on the target. The detectable label is then detected. In some embodiments, multiple targets can be detected by multiple quinone methide analog precursors interacting with different enzymes without the need for an enzyme deactivation step.
US12215116B2	Arginase inhibitors and methods of use Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.
US12215114B2	Processes and intermediates for producing diazaspiro lactam compounds Processes for producing diazaspiro lactam compounds and intermediates useful in the processes.
US12215113B2	Crystalline forms of N[4[4-(4-Morpholinyl)-7H-Pyrrolo[2-3-D]Pyrimidin-6-yl]Phenyl]-4-[[3(R)-[(1-Oxo-2-Protein-1-yl)Amino]-1-Piperidinyl]Methyl]2-Pyridinecarboxamide] Described herein is N-[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-4-[[3(R)-[(1-oxo-2-propen-1-yl)amino]-1-piperidinyl]methyl]-2-pyridinecarboxamide (Compound A) (Formula I), including crystalline forms, solvates, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions or pharmaceutical formulations that include the compound, as well as methods of using the compound, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, diabetes, and inflammatory diseases or conditions.
US12215104B2	Anti-biofilm compounds The present invention provides non-peptide compounds that mimic the streptococcal SspB Adherence Region (BAR) and function as inhibitors of P. gingivalis adherence to streptococci. The invention also provides methods of making and using the inhibitors.
US12215103B2	Fused imidazole derivative, preparation method therefor, and medical use thereof Disclosed are fused imidazole derivatives, preparation methods therefor and medical uses thereof. Specifically, the present disclosure relates to a fused imidazole derivative as shown in general formula (IM), a preparation method therefor, a pharmaceutical composition containing the derivative, and the use of same as a therapeutic agent, in particular the use thereof as a GLP-1 receptor agonist, and the use thereof in the preparation of drugs for the treatment and/or prevention of diabetes.
US12215096B2	Matrix metalloproteinase (MMP) inhibitors and methods of use thereof Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.
US12215092B2	Pleiotropic pathway modifier compounds and method of treating diseases This patent document reveals a class of pleiotropic pathway modifier (known as PPM) compounds that facilitate the degradation of multiple targeted proteins and regulate various signaling events involved in cancer cell survival and proliferation, as well as immune response. These compounds effectively recruit disease-causing proteins for swift destruction through the ubiquitin-proteasome pathway, exhibiting potent anti-cancer, immunomodulatory, and anti-inflammatory properties. Additionally, disclosed herein are methods for treating diseases encompassing cancers, autoimmune disorders, infections, inflammations, and other ailments.
US12215088B2	Method for the industrial production of 2-halo-4,6-dialkoxy-1,3,5-triazines and their use in the presence of amines A method for stabilization of collagen matrices and of condensation of natural and synthetic polymers that uses 2-halo-4,6-dialkoxy-1,3,5-triazines in the presence of one or more amines as activating agents for reactions of crosslinking, condensation, grafting, and curing of collagen matrices, cellulose, modified celluloses, polysaccharides, acid unsaturated polymers, and chiral and non-chiral amines, etc. Forming an integral part of the present invention is also the method for production on an industrial scale of 2-halo-4,6-dialkoxy-1,3,5-triazines.
US12215084B2	2(1H)-pyridinones and their use to treat inflammatory conditions Disclosed is a novel compound and a process of preparing it. It has been shown to have anti-inflammatory activity and can be utilised in a wide range of cosmetic compositions. The compound is a 2(1H)-pyridinone of formula (1) in amide or enol form. It may be prepared by exposing a solution of piroctone olamine in an organic solvent or in water comprising at least one surfactant to UV radiation to degrade the piroctone olamine. The compound of formula (1) is separated from the degradation products by chromatography.
US12215081B2	Pharmaceutical intermediate This invention relates to 4-(4-fluorobenzylamino)-1-methylpiperidine trihydrate and a process for the preparation of 4-(4-fluorobenzylamino)-1-methylpiperidine trihydrate comprising treating 4-(4-fluorobenzylamino)-1-methylpiperidine with water.The invention also relates to a process for the preparation of pimavanserin comprising reacting 4-(4-fluorobenzylamino)-1-methylpiperidine trihydrate with 1-isobutoxy-4-(isocyanatomethyl)benzene; to a process for the preparation of a pimavanserin acid addition salt comprising reacting 4-(4-fluorobenzylamino)-1-methylpiperidine trihydrate with 1-isobutoxy-4-(isocyanatomethyl)benzene and converting pimavanserin into a pimavanserin acid addition salt, pimavanserin and pimavanserin acid addition salts obtainable by the process, and to the use of 4-(4-fluorobenzylamino)-1-methylpiperidine trihydrate for preparing pimavanserin or an acid addition salt thereof.
US12215080B2	Hydrazinyl-pyrrolo compounds and methods for producing a conjugate The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
US12215079B2	Method for separating mixed xylene A method for separating mixed xylene includes steps that the mixed xylene is subjected to adsorption separation by means of an adsorbent having a metal organic framework material, so that one or more of xylene isomers are separated out. An organic ligand in the metal organic framework material is 2,5-dihydroxy-1,4-benzoquinone. Xylene isomers can be effectively separated using this method.
US12215077B2	Methods of depolymerizing lignin Methods of depolymerizing lignin and products obtained therefrom. The methods include reacting lignin in a liquid solvent comprising an oxidation catalyst with the solvent being in contact with O2 gas. The solvent can include aprotic polar solvents. The oxidation catalyst can include heterogeneous catalysts. The methods can be used in the oxidative catalytic fractionation of raw biomass to generate soluble aromatic monomers and a solid carbohydrate residue. Depolymerized lignin products include phenolic and benzoquinone monomers, such as p-hydroxybenzoic acid, vanillin, syringaldehyde, vanillic acid, and/or syringic acid.
US12215075B2	Method for the production of MTBE and 1-butene from a C4 feed stream Systems and methods for producing MTBE and 1-butene are disclosed. A crude C4 hydrocarbon stream is obtained by removing butadiene from a C4 hydrocarbon mixture of a hydrocarbon cracking unit. The crude C4 hydrocarbon stream is then distilled to form (a) a first distillate stream comprising isobutylene, isobutane, 1-butene, or combinations thereof and (b) a first bottom stream comprising 2-butene, n-butane, a deactivating compound for catalyst of MTBE synthesis. The first distillate stream is then flowed to a MTBE synthesis unit to produce via reaction with methanol. The raffinate from the MTBE synthesis unit comprising isobutane and 1-butene is further separated in a distillation column to produce 1-butene.
US12215073B2	Integrated ethylene production process The invention relates to a process for the production of ethylene in an integrated configuration comprising (i) a steam cracker configuration which comprises a steam cracker unit, a water condensation unit and a carbon dioxide removal unit and (ii) an oxidative dehydrogenation (ODH) configuration which comprises an ODH unit and a water condensation unit, wherein an effluent coming from the ODH configuration, which effluent comprises unconverted ethane and ethylene, is fed to the steam cracker configuration at a position which is downstream of the steam cracker unit, and wherein unconverted oxygen, carbon monoxide and acetylene are removed from at least a portion of the stream coming from the ODH unit by oxidation of carbon monoxide and acetylene into carbon dioxide in an oxidation unit which is located at a position (a) which is downstream of the ODH unit, and (b) which is downstream of the steam cracker unit and upstream of the carbon dioxide removal unit of the steam cracker configuration.
US12215065B2	Methods for producing arylamine compound and electrophotographic photosensitive member A method for producing an arylamine compound, wherein a chemical compound represented by formula (B) is reacted by addition reaction with a carbon atom having a bound hydrogen atom on a benzene ring of a chemical compound represented by formula (A), in the presence of one or more acids selected from Lewis acids or sulfonic acids; to produce a chemical compound represented by formula (C) including a partial structure represented by formula (D).
US12215064B2	Compounds for chromatographic separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof The present invention relates to compounds of general formula (I), wherein —X is selected from a group consisting of H; C1 to C6, alkyl; halogen (F, Cl, Br or I); Y is selected from a group consisting of nitrogen; N-oxide; Z1, Z2, Zm, wherein m is 1 or 2, are independently selected from the group consisting of —CH2—CH2— and —CH2—CH2—CH2; A, Am, wherein m is 1 or 2, are independently selected from H; —CH2COOH; —CH2C(O)NH2; —CH2P(O)(OH)2, and n is 1 or 2; R1, R2, R3 are independently H; C1 to C6, alkyl; C1 to C6 alkyloxy; C6 to C10 aryloxy; benzyloxy; C1 to C6 alkylthio; C6, to C10 arylthio; F; Cl; Br; I; OH; SH; NH2; C1 to C6, alkylamino; di(C1 to C6, alkyl)amino; C1 to C6 acylamino; di(C1 to C6 acyl) amino; C6 to C10 arylamino; di(C6 to C10 aryl)amino; CN; OH; nitro; COORn, C(O)NHRn, C(O)N(Rn)2, wherein Rn is independently H or C1 to C10 alkyl or C6, to C10 aryl; and/or neighboring two of R1, R2, R3 together with neighboring two carbon atoms of the aromatic cycle form a six-membered ring, optionally substituted with one or more substituents independently selected from the group consisting of OH, SH, CF3, F, Cl, Br, I, C1 to C6, alkyl, C1to C6, alkyloxy, C1 to C6 alkylthio, NH2, C1 to C6 alkylamino, di(C1 to C6 alkyl)amino, NO2, COOH, COORn, C(O)NHRn, C(O)N(Rn)2, wherein Rn is WO 2020/244686 A1 independently H or C1 to C10 alkyl or C6 to C10 aryl; with the proviso that when n is 2 and all of Z1, Z2, Zm are —CH2—CH2—, then A is not —CH2COOH; for chromatographic separation of rare earth elements and/or s-, p- and d-block metals, as well as to the method of the separation of rare earth elements.
US12215061B2	Insert and cutting tool An insert of the present disclosure includes a boron nitride sintered body including a first surface. In a transmission X-ray diffraction of a cross section of the boron nitride sintered body vertical to the first surface, X-ray intensity at a top of a 111 diffraction peak of cubic boron nitride in a direction vertical to the first surface is IcBN(111)v. X-ray intensity at a top of a 002 diffraction peak of compressed boron nitride is IhBN(002)v. X-ray intensity at a top of a 111 diffraction peak of the cubic boron nitride in a direction parallel to the first surface is IcBN(111)h. X-ray intensity at a top of a 002 diffraction peak of the compressed boron nitride is IhBN(002)h. A compressed boron nitride content value obtained from these X-ray intensities is larger than 0.005. A cubic orientation value is larger than 0.5, and a compressed boron nitride orientation value is larger than the cubic orientation value.
US12215053B2	Electronic devices with textured glass and glass ceramic components Electronic devices including a textured component such as a cover member positioned over one or more components of the electronic device. Different surface regions of the textured component may be textured differently in order to provide optical contrast. For example, differently textured surface regions may differ in gloss, translucency, or both. In some cases the cover member defines a protruding feature and a surface region of the protruding feature is textured differently than an adjacent surface region.
US12215051B2	Glass production method and industrial glass-making facility The invention relates to a glass production method comprising charging a glass furnace with solid-state raw materials, said raw materials comprising granular glassy sodium silicate and having a moisture content of less than 1%, preferably 0%, by weight, and powdered calcium oxide.
US12215049B2	Cover plate structure for glass fiber tank furnace forehearth A cover plate structure for a glass fiber tank furnace forehearth includes chest wall bricks at two sides of the forehearth, cover plate bricks each spanning between a top end of at least one of the chest wall bricks at one of the two sides of the forehearth and a top end of at least one of the chest wall bricks at another one of the two sides of the forehearth, a thermal insulation layer covering outer surfaces of the cover plate bricks and the chest wall bricks, and a gap-covering brick fixed between the cover plate bricks and the thermal insulation layer and covering a gap between adjacent ones of the cover plate bricks.
US12215044B2	System for removal of phosphorus and nitrogen from water Various embodiments relate to methods and systems for removing phosphorus and/or nitrogen from water. A method of removing phosphorus and nitrogen from water includes passing starting material water including nitrogen and phosphorus through an elevated pH phosphorus removal stage. The method includes passing the water through an electrolytic nitrogen removal stage. The method includes passing the water through a galvanic phosphorus removal stage. The water produced by the method has a lower phosphorus concentration and a lower nitrogen concentration than the starting material water.
US12215041B2	Water filter with quick release device A water filter includes a filtering head, a filter bottle assembly, a switch member, and a quick release device. The filtering head includes a flow channel module. The filter bottle assembly includes a filter bottle. The quick release device includes a press lever, two links, and two push members. When the press lever is pivoted, the two links and the two push members are driven by the press lever to move the filter bottle simultaneously so that the filter bottle is mounted on or detached from the filtering head quickly. A switch member functions as a waterway switch to control a water supply of the filtering head and functions as a locking mechanism for locking or unlocking the quick release device.
US12215039B2	Synthesis, capping, and dispersion of TiO2 nanocrystals The preparation of monodispersed TiO2 nanocrystals with nanocrystal size between 1-30 nm is described herein. These TiO2 nanocrystals are used to prepare dispersions into solvents, formulation into monomers, oligomers, and polymers, and nanocomposites from the resulting formulations. Dispersions of nanocrystals can be formed in various solvents at high loading, high transmittance, and low viscosity. Formulations incorporating these nanocrystals and a matrix material are highly stable, where the resulting nanocomposites have high refractive index and are optically transparent in the visible wavelengths, with very little or no scattering.
US12215038B2	Method for preparing two-dimensional ordered mesoporous nanosheets by inorganic salt interface-induced assembly A method for preparing two-dimensional (2D) ordered mesoporous nanosheets by inorganic salt interface-induced assembly includes the following steps: carrying out, by using a soluble inorganic salt as a substrate and an amphiphilic block copolymer as a template, uniform mass diffusion of a target precursor solution at an inorganic salt crystal interface through vacuum filtration or low-speed centrifugation; forming a single-layer ordered mesoporous structure by using the solvent evaporation-induced co-assembly (EICA) technology; and promoting, through gradient temperature-controlled Ostwald ripening, the evaporation and induced formation of an organic solvent, and removing the template in N2 to obtain a 2D single-layer ordered mesoporous nanosheet material. The assembled nanosheet material has a large pore size, regular spherical pores and orderly arrangement. By changing the type of the precursor, a variety of mesoporous metal oxides, metal elements, inorganic non-metal nanosheets are synthesized.
US12215022B2	Microelectromechanical microphone with reduced overall size A microelectromechanical microphone including a microphone unit made from a first substrate, the microphone unit including a movable element capable of being displaced under the effect of a pressure difference and a device for measuring the displacement of the movable element, a cover made from a second substrate, the cover having a first recess, first device for electrically connecting the measurement device to a control unit, the microphone unit and the cover delimiting between them a vacuum space housing the measurement device and a first cavity, from the first recess, partly closed by the movable element, the vacuum space and the first cavity being insulated in a sealed manner from each other, the microphone including a device for mechanically transmitting the displacement of the movable element to the measurement device and a sealed insulation element through which the transmission device passes.
US12215020B2	MEMS device with damping fluid vertically sandwiched between moving and non-moving structures A microelectromechanical system (MEMS) device includes a substrate, a suspended element and a damping structure connected to the suspended element and one or more fluid confinement structures. The suspended element is connected to a fixed part of the substrate by one or more flexures configured to permit movement of the suspended element relative to a fixed part of the substrate. The damping structure extends into a gap between the suspended element and the fixed part of the substrate. The damping structure includes one or more winglets that protrude over a recessed portion of the fixed part of the substrate. The fluid confinement structures are formed by the recessed portion of the fixed substrate and are configured to permit movement of the damping structure over the recessed portion of the substrate and confine a viscoelastic fluid to the limited portion of the gap underneath the winglets.
US12215019B2	Electrostatic device, electrostatic device intermediate body and production method An electrostatic device includes: a fixed portion, a moveable portion, and an elastically-supporting portion that are formed in a same substrate; and a first glass package and a second glass package that are anodically bonded to each other on one and the other of front and back surfaces of the substrate with the fixed portion and the elastically-supporting portion separated from each other, the second glass package forms a sealed space in which the moveable portion is arranged between the first and second glass packages, an electret is formed at least partially in the fixed portion and the moveable portion, and a first electrode connected to the fixed portion and exposed on an outer surface of the second glass package and a second electrode connected to the elastically-supporting portion and exposed on the outer surface of the second glass package are formed in the second glass package.
US12215018B2	Method for manufacturing package structure A method for manufacturing package structure is provided, including: providing a substrate having recesses; forming first MEMS chips on the substrate, each with a through-substrate via, and a first sensor or microactuator on the lower surface, located in one of the recesses; forming first intermediate chips on the substrate, each respectively on one of the first MEMS chips, having a through-substrate via, and including a signal conversion unit, a logic operation unit, control unit, or a combination thereof; forming second MEMS chips on the first intermediate chips, each with a through-substrate via, having a second sensor or microactuator on its upper surface, wherein the package structure includes at least one of the first sensor and the second sensor; and forming first capping plates on the second MEMS chips, each providing a receiving space for the second sensor or microactuator on the upper surface of each second MEMS chip.
US12215016B2	Piezoelectric anti-stiction structure for microelectromechanical systems Various embodiments of the present disclosure are directed towards a microelectromechanical system (MEMS) device. The MEMS device includes a first dielectric structure disposed over a first semiconductor substrate, where the first dielectric structure at least partially defines a cavity. A second semiconductor substrate is disposed over the first dielectric structure and includes a movable mass, where opposite sidewalls of the movable mass are disposed between opposite sidewall of the cavity. A first piezoelectric anti-stiction structure is disposed between the movable mass and the first dielectric structure, wherein the first piezoelectric anti-stiction structure includes a first piezoelectric structure and a first electrode disposed between the first piezoelectric structure and the first dielectric structure.
US12215012B2	Forklift and control method for forklift A forklift includes a vehicle body, a fork that mounts a pallet, and a sensor provided in an insertion portion of the fork. The forklift inserts the insertion portion into an insertion opening, while moving the fork. When the sensor detects a proximity state, in which the insertion portion has approached a facing surface to such an extent that a distance between the insertion portion and the facing surface is less than or equal to a specified value, the forklift executes a stopping process that stops movement of the fork. The forklift executes an avoidance process that tilts and vertically moves, after the stopping process, the fork to separate the insertion portion away from the facing surface such that a position of the insertion portion with respect to an entrance of the insertion opening does not change in an up-down direction of the vehicle body.
US12215010B2	Rear mounted lift for over-the-road vehicle A powered forklift assembly is configured to be operably mounted on an over-the-road vehicle to shift a load relative to a chassis of the vehicle. The powered forklift assembly includes a shiftable forklift and a vehicle bed. The shiftable forklift includes an extendable mast and a fork mechanism. The fork mechanism is attached to and is vertically shiftable relative to the mast and configured to support the load.
US12215005B2	Support for a trolley, and overhead transport device having such a support A support for a trolley, having a running surface that is formed on the support for the trolley, an upper chord, a lower chord and braces that connect said chords together, wherein the braces are designed to be flat, and each brace has a main surface that faces away from the support longitudinally between the upper chord and the lower chord. Two of the braces form a brace pair in each case and are arranged next to one another as viewed in the direction of the longitudinal axis of the support, preferably on the outside of opposite longitudinal sides of the support. To provide such a support, the flat braces are releasably secured to the upper chord and/or to the lower chord. The invention also relates to an overhead transport device having such a support and a trolley that can be moved along the support on the running surface.
US12214996B2	Notification system A notification system includes: a notifier which notifies an operator of a state of a lifting magnet; a sensor which detects at least one of a voltage, an electric current, and an electric power supplied for exciting the lifting magnet; a determination part which determines, based on detection data from the sensor, whether an attraction quantity of the lifting magnet reaches a maximum attraction quantity after excitation of the lifting magnet is started; and a notification control part which causes the notifier to notify that the attraction quantity reaches the maximum attraction quantity when the determination part determines that the attraction quantity reaches the maximum attraction quantity.
US12214994B2	Brake disc releasing device, turning device, elevator rescue kit and method A turning device includes a hand disc coupled to an input shaft; a reduction gear set accommodated in a housing and connected to the input shaft and an output shaft; and a shaft connector for connecting the output shaft and a motor spindle.
US12214991B2	Foil transfer device A foil transfer device includes a foil transfer film cartridge, a housing, a display, a detector, and a controller. The foil transfer film cartridge includes a supply reel on which a foil film is wound. The housing allows the foil transfer film cartridge to be removably installed therein. The display is provided on the housing to display information. The detector detects foil film information in a state where the foil transfer film cartridge is installed in the housing. The foil film information includes at least one item selected from a group comprising a color of the foil, a width of the foil film, and a widthwise position of the foil film in a direction of the width of the foil film. The controller causes the foil film information detected by the detector to be shown on the display.
US12214990B2	Sheet feeding apparatus and image forming apparatus A sheet feeding apparatus includes a first feeder, a second feeder, and processing circuitry. The first feeder includes a sheet stacker, an air blower, a suction feeder, and a remaining amount detection sensor. The air blower blows air to float an uppermost sheet. The suction feeder sucks and feeds the sheet. The remaining amount detection sensor detects a remaining amount of sheets stacked. The processing circuitry determines whether the remaining amount of sheets in the first feeder is smaller than a threshold, causes the first feeder to perform a feeding operation of feeding the sheet floated by the air blower to the suction feeder in response to a determination that the remaining amount is equal to or greater than the threshold, and causes the second feeder to feed a sheet instead of the first feeder in response to a determination that the remaining amount is smaller than the threshold.
US12214989B2	Media sheet conveyance with transport assemblies In an example, a media sheet conveyance system includes a first transport assembly, a plurality of subject transport assemblies, and a controller. The first transport assembly includes an endless first belt having a plurality of rows of holes, including a first and a second edge row separated by a distance “x”. Each subject transport assembly includes an endless subject belt having a subject edge row of holes, with a distance to a nearest edge row of an adjacent transport assembly being less than or equal to the distance “x.” The controller is to, in order to convey a media sheet, control a first drive roller to circulate the first belt over a first vacuum element set, and control a subject drive roller to circulate a subject belt over a subject vacuum element.
US12214982B2	Recording device and air blowing control method of recording device A medium discharge unit that discharges a medium subjected to recording by a recording unit, a placement unit at which the medium discharged by the medium discharge unit is placed, the placement unit being inclined with a downstream side in a discharge direction in which the medium is discharged being positioned, in a vertical direction, above an upstream side in the discharge direction, an air blowing unit that blows air from above toward the medium discharged from the medium discharge unit, and a control unit that controls the air blowing unit are included. The control unit can attenuate air blowing by the air blowing unit, based on information of an interval between a preceding medium and a following medium that are to be discharged from a discharge position of the medium discharge unit to the placement unit, when the preceding medium is discharged from the discharge position.
US12214981B2	Method and plant for producing logs of thin products Method for producing logs (B1, B2) of continuous thin products, or web products, in optimized manner by tracking defects in the surface and/or in the thickness detected on the products, comprising •—a step of continuously winding a thin product (T) into logs (B1, B2) on a winding machine, in order to produce at least one primary log, •—a step of identifying any defects in the surface and/or the thickness of said continuous thin product, •—a step of storing in a database system (31), outside the primary log, information related to said defects comprising at least the position of said defects with respect to a reference system associated with the primary log, •—a step of assigning a primary ID code to said primary log, •—a step of marking said primary log with said primary code, •—a step of associating, in said database system (31), information on said defects with the primary ID code of the primary log, so that, in said database, to a given primary ID code information are associated related to defects in the surface and/or the thickness of the respective primary log, that can be identified based on their position on the primary log, •—a step of using said information on the defects of the primary log, stored in the database system (31), in order to optimize at least one subsequent processing of the product wound into the respective primary log, said use providing for recognizing the primary code of the primary log being processed and the processing of the product based on the information on the surface defects associated to the primary log.
US12214978B1	Platform apparatuses In various embodiments, an automated platform may autonomously move around a site, loading dock, dock leveler, and/or trailer to transport goods. In one or more embodiments, the automated platform may be loaded with goods and, once loaded, navigate a path from a loading area onto a trailer autonomously. In some embodiments, once the automated platform is loaded onto the trailer, the automated platform may utilize hydraulics to extend legs to the ground with enough force so that the automated platform wheels are not touching the ground in the trailer, which stabilizes the automated platform while it is being hauled to a different site. In at least one embodiment, once the trailer is at the different site, the automated platform may autonomously unload itself out of the trailer and navigate over a dock leveler, through the loading dock, and to an unloading area.
US12214973B2	Modular manufacturing system and method for use thereof The system and method use one or more manufacturing base modules can each have a first side, a second side opposite from the first side, a third side to the left of the first side, a fourth side to the right of the first side, a directional movement portion, and at least one operational attachment attached relative to at least two of the at least three base modules. For a given base module, the directional movement portion can define a working area for performing at least one operation on one or more articles passing through the working area, and the operational attachment can perform the at least one operation on the one or more articles. The one or more base modules can be arranged in various different arrangements and layouts with respect to one another to create an assembly line to create finished or semi-finished products from the one or more articles.
US12214972B2	System and method for parcel slug accumulation and redistribution Embodiments include a parcel processing system and methods for operating the same. The parcel processing system includes a collector configured to receive a flow of parcels and a slug accumulation system configured to receive the flow of parcels and produce a normalized bulk flow of parcels. The parcel processing system also includes a bulk transport conveyor configured to receive the normalized bulk flow of parcels and a singulator configured to receive the normalized bulk flow of parcels from the bulk transport conveyor. The normalized bulk flow of parcels is a flow of parcels having an approximately constant parcel density traveling at a fixed speed.
US12214965B1	Digitally adjustable and reversible vibrating conveyor The invention is a digitally adjustable and reversible vibrating conveyor. It provides a trough to which sinusoidal motion is applied variably and adaptably. A motor turns a shaft in an oscillating or rocking motion about its longitudinal axis. Variable settings on a controller determine the oscillation parameters for the motor. These settings particularly address three variables: the oscillation speed; the arc angle through which the oscillation proceeds, and a net angle that represents the mid-point for the oscillation relative to vertical. The invention allows for adaptation of vibrating conveyors without adjusting them mechanically, and enables reversal of load transfer direction when desired.
US12214956B1	Enhanced self-closing lid for containers A container may include a cargo bay for holding items; a lid able to slide between a closed position to an open position relative to the cargo bay; a check strap operatively connected to the lid and able to move vertically in a first direction toward the lid as the lid slides from the closed position to the open position, and to move vertically in a second direction opposite the first direction as the lid slides from the open position to the closed position; and arms operatively attached to rollers and to one or more tension devices, wherein when the check strap moves vertically in the first direction, the check strap separates the rollers and causes the arms to pull the one or more tension devices, and wherein when the check strap moves vertically in the second direction, the one or more tension devices cause second rotation of the arms.
US12214954B1	Cord or rope storage bag for preventing knots and a method using the same A cord or rope storage bag for preventing knots is disclosed herein. The cord or rope storage bag includes a bag body portion, the bag body portion defining an interior compartment configured to store a cord or rope therein; a first cord or rope end retention device, the first cord or rope end retention device configured to be coupled to a first end of the cord or rope; and a second cord or rope end retention device, the second cord or rope end retention device configured to be coupled to a second end of the cord or rope. An attachment of the first and second ends of the cord or rope to the respective first and second cord or rope end retention devices is configured to prevent a formation of knots in the cord or rope being stored in the interior compartment of the cord or rope storage bag.
US12214952B2	Multi-chamber mixing beverage container A multi-chamber mixing beverage container is used to retain and selectively mix different beverage ingredients to make and consume a custom beverage. The multi-chamber mixing beverage container may include a container body, a storage base, an additive dispensing mechanism, and a cap. The container body retains a quantity of liquid that serves as the base to mix a custom beverage. The container body further facilitates the mixing of the beverage ingredients and the ease of consumption of the custom beverage. The storage base retains different beverage ingredients separate from each other to be selectively mixed with the quantity of liquid retained within the container body. The additive dispensing mechanism enables the selective mixing of an amount of one or more beverage ingredients from the storage base with the quantity of liquid within the container body. The cap keeps the container body sealed until the mixed beverage is consumed.
US12214945B2	Closure device for a container A closure device for a container having a neck including an annular flange, the closure device comprising: a cap body; a tamper evident (TE) band positioned below the annular flange when assembled in the container; a first hinge and a second hinge defined on the cap body; a leash connected to the TE band, the first hinge and the second hinge; the leash allowing for the cap body to be separated from the TE band during opening, but to remain connected thereto via the leash; a tongue protruding from the cap body between the first and second hinges; when the cap body is actuated from a closed configuration relative to the neck to a fully open position: the leash is configured to retain the cap body to the TE band; an interaction of the tongue and the neck is configured to retain the cap body in the fully open position.
US12214944B2	Closure device for a container A closure device for a container with a container opening has a lid element for closing the container opening, a chamber assigned to the lid element and an inner housing. The chamber and the inner housing have closing and opening elements that correspond to one another. The chamber locks with the inner housing, the lock with the inner housing being offset radially inwards in respect of a vertical of the closure device over a greatest width of the chamber in the offset direction. In order to specify a closure device which allows emptying of the chamber as the lid element is removed in an easy-to-handle fashion, with further preferred favorable manufacturability of the closure device, the lock in the vertical direction is designed separately from a shoulder section of the inner housing formed on the base side under the lock.
US12214941B2	Self-centering features for stackable containers A container includes a polygonal section comprising lateral walls surrounding an interior space. An upper wall forms a top bound on the interior space. A lower wall forms a bottom bound on the interior space. An alignment tab straddles a respective one of the upper fold lines. The alignment tab also has an intermediate fold line between the first and second ends of the alignment tab that is closer to the first end than to the second end, such that the alignment tab projects upward from the upper wall and separates two vertical, inward facing alignment edges at an upper end of the adjacent one of the lateral walls. A retention tab extends downward from the adjacent one of the lateral walls and is configured to engage two vertical, inward facing alignment edges of a similar container for alignment in a stack.
US12214937B2	Port system and method for an embalming machine An embalming machine for mixing of fluids and cleaning of a reservoir may include a reservoir. The embalming machine may include a tube extending from a lower portion to an upper portion of the reservoir, the tube providing a pathway for fluid to travel to the reservoir. The embalming machine may include a port connected to an end of the tube adjacent to the upper portion of the reservoir, the port being configured to dispense the fluid traveling through the tube and into an interior of the reservoir.
US12214934B2	Closure mechanism for product container A cosmetic product container may include a cap body having first and second ends and defining a cap cavity, a cap liner operably coupled with the cap body and being movable along a length thereof, a resilient member operably coupled with one of the cap body or the cap liner, and a coupling protrusion operably coupled with the other of the cap line or the cap body. In response to moving the cap body relative to the cap liner in a first direction, the resilient member slidably engages the coupling protrusion and moves to an energized position. Continued movement of the cap body relative to the cap liner causes the resilient member to urge the cap body in the first direction.
US12214933B2	Tubular container and method for producing same Provided is a tubular container capable of improving extractability of contents inside the container. The tubular container includes: a trunk portion having a tubular shape one end of which is closed, the trunk portion being formed by using a film member containing a resin material, and being capable of storing contents therein; and a spout portion attached to the other end of the trunk portion, and capable of closing the other end of the trunk portion. On a peripheral portion of the spout portion, the other end of the trunk portion is attached to a surface, of the spout portion, on a side opposite to the one end of the trunk portion.
US12214930B2	Stackable liquid vessel and multi-vessel arrangement A stackable liquid vessel may be able to receive, store, and dispense various liquids or fluids, such as beverages, cooking oil or vinegar, motor oil, and/or other appropriate materials or substances. Each stackable liquid vessel may be able to at least partially couple to at least one other stackable liquid vessel. An arrangement of stackable liquid vessels may utilize perforated slipsheets to reduce material usage when packing, shipping, storing, and/or displaying multiple stackable liquid vessels (e.g., a pallet of stackable vessels).
US12214928B2	Resealable pop top lid A pop top lid for cylindrical fluid containers is disclosed. The lid includes an end shell with a scored line defining a tear panel, a stay-on tab assembly, and a rivet for attaching the assembly to the shell. The stay-on tab assembly features a pocketed tang with a central portion containing a pivot hole for the rivet. The assembly includes a top cover and bottom plate, spaced apart by a gap on the leading edge. An aperture point is connected to the pocketed tang and can be rotated. A shearing edge is attached to the central portion and extends radially behind the aperture point. In an embodiment, the bottom plate is embossed to facilitate sliding of the shearing edge under the end shell wall when the pocketed tang is rotated, achieving a resealing clamp action by securely placing the embossed shape into the tear panel opening.
US12214927B2	Pulp container with fused junction and method of making same Molded pulp containers with fused junctions and methods of making of same are provided. The present invention provides a pulp container, comprising a molded pulp body, wherein the body comprising a bottom and at least one side wall forming a cavity, wherein the at least one side wall comprising a upper rim, a neck, wherein the neck comprising a upper closure part and a lower rim, a fused junction, wherein a part of the upper rim of the at least one sidewall of the body and a part of the lower rim of the neck are aligned and fused together. The fused junction may be formed by ultrasonic welding.
US12214926B2	Labeling machine A labeling machine, which includes a conveyor of containers to be labeled along an advancement path and at least one labeling unit arranged along the advancement path and provided with a respective transfer drum that can move in rotation about its own axis, with respect to a supporting base, and which is adapted to receive, in adhesion to its lateral surface, from a feeder unit, labels to be applied to the containers, at a feeding station, and to transfer the labels received at the feeding station to respective containers that arrive from the conveyor at a transfer station which is angularly spaced apart from the feeding station about the axis of the transfer drum; at least one portion of a sector of the lateral surface of the transfer drum is rotatably movable, with respect to the remaining part of the transfer drum.
US12214925B2	Methods and machine for forming a container from a blank and applying an identification tag A machine for forming a container from a blank of sheet material includes a frame and an identification tag applicator mounted to the frame. The blank includes a first surface that forms an interior surface of the container and a second surface that forms an exterior surface of the container. The identification tag applicator is configured to apply an identification tag to the first surface of the blank. The machine also includes a mandrel assembly mounted to the frame and located operationally downstream from the identification tag applicator. The mandrel assembly includes a mandrel having an external shape complimentary to an internal shape of at least a portion of the container. The machine also includes a lift assembly configured to lift the blank having the identification tag adhered thereto towards the mandrel and wrap the blank about the mandrel.
US12214924B2	Method of opening an outer bag of a pre-filled double-bag and an opening device therefore A method of opening an outer bag of a pre-filled double-bag including a bag content and an opening system. A wall of the outer bag includes a cellulose-based material and a wall of the inner bag may include a plastic-based material enclosing an inner compartment including the bag content.The method may include an opening operation performed by the opening system, so as to open the outer bag leaving the inner bag substantially intact.The opening system may include a laser arrangement including one or more laser units emitting laser light having wavelengths in the range of 7-13 μm. The opening operation may include acts of exposing a wall area of the outer bag to the laser light, so as to at least provide a perforation of the outer bag in the exposed wall area.
US12214922B2	Method and arrangement for packaging groups of containers, such as bottles, cans, and similar containers, for containing beverages or other products A beverage container handling machine, such as a beverage container filling machine or a beverage container closing machine, is used to handle beverage containers, such as bottles, cans, and similar containers, which containers are configured to hold or contain a beverage, such as water, soft drinks, beer, wine, and juices, or a similar product for transport and consumption by consumers of beverages and similar products. Container packages, such as multipacks, are used for transporting groups of beverage containers, such as bottles, cans, and similar containers, for containing beverages or other products.
US12214921B2	Strapping head monitoring system for packing coil through selective sensing of binding force of band for packing coil The present invention relates to strapping head monitoring system for packing coil through selective sensing of binding force of band for packing coil. The system discloses a band sensing unit that selectively senses a band for coil wrapping to obtain binding information of a band for coil wrapping in the strapping head binding a coil through a band for coil wrapping; a binding monitoring unit that selectively controls a binding force of a band for coil wrapping by monitoring a binding force of a band for coil wrapping in real time; and an operator terminal unit that interworks with a binding monitoring unit to enable an operator to control a binding force of a band for coil wrapping in real time.
US12214919B2	Tape packing apparatus Disclosed is a tape packing apparatus and method. The tape packing apparatus including: a supporting frame; a drive unit configured to install on the supporting frame; a tape head pressing arm configured to install on the supporting frame and connected to the drive unit, and the drive unit configured to drive the tape head pressing arm to move to a packing position such that the tap head is pressed onto an object to be packed; a cutting module configured to install on the supporting frame and connected with the driving unit, and the driving unit is constructed to drive the cutting module to the packing position to cut the tape. The tape packing apparatus provided by the embodiment of the present invention has good packing effect, can effectively shortens the packing time, has high packing efficiency, and saves manpower and costs.
US12214916B2	Machine arrangement and method for filling and sealing containers The present invention relates to a machine arrangement, in particular for processing pharmaceutical products, comprising a processing station (2) for filling and sealing containers, in particular with pharmaceutical products, a handling device (3) for feeding and removing the containers into the machine arrangement, wherein the handling device (3) is designed to feed and remove containers only from exactly one side of the machine arrangement into the machine arrangement, wherein the processing station (2) has at least one work region (4) for receiving an empty container, at which the empty container is filled and sealed, wherein the processing station (2) has at least one storage region (5) for the temporary storage of filled and sealed containers, and wherein the handling device (3) is designed to feed empty containers to the processing station (2) and remove filled and sealed containers from the storage region (5).
US12214915B2	Strapping device having a device for rotating a package A strapping device for strapping packages, having a packing table on which the package passes through the strapping device along a movement path, having a strapping frame, having a rotation device in the packing table, having a strapping channel which is formed by the strapping frame, and having closure flaps which close a channel opening of the channel member which is arranged in the packing table.
US12214909B1	Dispensing hinge assembly Technology is disclosed herein for a payload dispensing hinge assembly. The payload dispensing hinge assembly has a first hinge-half and a second hinge-half that are joined by a hinge pin. The first hinge-half may be connected to a payload that is to be dispensed at a target angle. The second hinge-half may be connected to a payload base. The first hinge-half may have a first mounting bracket and a rotatable arm that are shaped to form interlocks that serve to dis-engageably link these two components. A biasing mechanism rotates the rotatable arm and hence the first mounting bracket and payload about a hinge line. The second hinge-half has a hinge stop that stops the rotation of the rotatable arm at a target angle, whereby the first bracket dis-engages from the rotatable arm to dispense the payload at the target angle.
US12214903B2	Apparatus for and a method of deicing a ducted fan engine A ducted fan engine is deiced using a ground support deicing apparatus having a support structure, a plurality of sonic wave transmitters, an imaging device, and a controller that controls the sonic wave transmitters to emit sonic waves at varying frequencies. A deicing program causes the controller to control (a) providing imaging signals to obtain image data from imaging sensors, (b) receiving image data provided by each of the imaging sensors, and generates images of at least one component part of the engine, (c) detecting a presence or an absence of ice on the at least one component part of the engine, and (d) controlling the plurality of sonic wave transmitters to emit sonic waves in a given frequency range so as to remove the ice from the component part of the engine.
US12214899B1	Propeller restraint kits for turboprop aircraft Propeller restraint kits for turboprop aircraft are provided which include at least one, and preferably a pair, of propeller restraint systems. Each propeller restraint system will preferably include an open-ended propeller restraint boot that may be formed of a flexible and durable fabric material which is sized and configured for placement over the tip of a propeller blade. A cowling attachment assembly is provided in the kit and is adapted to being attached to an aircraft cowling skin. A propeller boot tether strap of predetermined length interconnects the propeller restraint boot and the cowling attachment assembly. The cowling attachment assembly includes (i) a quick disconnect (QD) pin assembly connected to a terminal end of the propeller boot tether strap, and (ii) a pin receiver adapted to being positionally attached to an interior portion of the aircraft cowling skin.
US12214897B2	Escape route marking in vehicles An illumination element marks escape routes in vehicles. The illumination element includes a planar substrate, which has: a base surface configured for fastening on a first side; and at least one planar electrical lighting element on a second side. A ratio of a surface area of the base surface to a thickness of the illumination element is greater than 500 mm, and a ratio of the surface area of the base surface to a mass of the illumination element is greater than 100 mm2/g.
US12214896B2	Electrical supply system of an aircraft An electrical supply system (10) with first and second electrical sourced (S1, S2), coupled together to electrically supply electrical loads (Z1, Z2, Z3 . . . Zn) of an aircraft. The first electrical source (S1) is mechanically coupled to a primary energy source (12), to which at least one other energy consumer (16) is coupled. A controller (30) controls the first and second electrical sources (S1, S2) so that the power drawn by the first electrical source from the primary energy source (12) corresponds to a difference between an instantaneous nominal power capable of being delivered by the primary energy source and an instantaneous power drawn by the energy consumer (16), and an electrical power delivered by the second electrical source is a sum of an electrical power delivered by the first and second electrical sources which corresponds to an instantaneous electrical consumption of the electrical loads.
US12214895B2	Systems and methods for energy transport using an unmanned aerial vehicle An unmanned aerial vehicle (“UAV”) system for energy transport includes a UAV having an energy tank configured to transport energy, a processor, and a memory. The memory includes instructions which, when executed by the processor, may cause the system to receive a first location for collecting or releasing the energy, determine an energy level of the energy tank, and transport the energy by the UAV to or from the first location based on the determined energy level.
US12214887B2	Environmental control system including humidity sensor An environmental control system of an aircraft includes a primary heat exchanger, a secondary heat exchanger and an air cycle machine. The air cycle machine includes a compressor fluidly coupled to an outlet of the primary heat exchanger and an inlet of the secondary heat exchanger, a dehumidification system arranged in fluid communication with the outlet of the secondary heat exchanger, a first turbine fluidly coupled to an outlet of the secondary heat exchanger and optionally a second turbine disposed downstream of the first turbine that receives air from the first turbine in a normal mode a first humidity sensor disposed fluidly between the first turbine and the second turbine that measures humidity of air that has left the first turbine as it enters the second turbine in the normal mode.
US12214886B2	Ventilation systems and methods for internal cabins of vehicles A system includes one or more distribution nozzles associated with a seat within an internal space, and a return air grill associated with the seat. Airflow is directed from the one or more distribution nozzles toward and into the return air grill. A method includes associating one or more distribution nozzles with a seat within an internal space, associating a return air grill with the seat, and directing airflow from the one or more distribution nozzles toward and into the return air grill.
US12214885B2	Controlling movement of a table in an aircraft passenger suite An aircraft passenger suite (200) and method are provided. The aircraft passenger suite comprises a console (150) and a table (130) movably mounted to the console, the table being moveable along a table path between a first position and a second position. A controller (210) controls electro-mechanical movement of the table along the table path. The controller comprises an initiation input for receiving an instruction to initiate electro-mechanical movement of the table. The suite comprises sensing equipment for sensing if any obstacle is present on the table path and providing, to the controller, an indication of whether or not any obstacle is present on the table path. The controller is configured to prevent electro-mechanical movement of the table along the table path if the controller receives an indication that an obstacle is present on the table path.
US12214884B2	Expandable lavatory and cabin configuration including dedicated seating area and expandable lavatory An expandable lavatory and an aircraft cabin configuration including the same. First, second and third walls form the lavatory interior and the third wall is repositionable to expand the lavatory interior footprint to accommodate a wheelchair. The third wall carries a door deployable when the third wall is in the expanded configuration such that the wheelchair can access the lavatory interior via an exit pathway. A first door positioned in the second wall provides access to the lavatory interior via a longitudinal aisle. In some embodiments, a wheelchair securement area is positioned longitudinally aligned with the second door, when the second door is deployed, such that wheelchair access to the lavatory is provided through second door when the lavatory is in the expanded configuration.
US12214880B2	Passenger-oriented path estimation and display Embodiments described herein relate to providing path information of a vehicle to vehicle passengers, and the provided path information may be configured according to passenger-related constraints. In one embodiment, a method for providing passenger-oriented path information via an in-flight entertainment system is described. The method includes making a determination that a graphical display of an estimated first path of the commercial passenger vehicle traveling via a route between an origin and a destination intersects a constrained area. The estimated first path is estimated as a straight-line path between consecutive waypoints along the route. The method further includes, based on the determination that the estimated first path intersects the constrained area, determining a second path for display that does not intersect the constrained area. The method further includes causing a display of the second path on an IFE display associated with a passenger.
US12214879B2	Aircraft wing with trailing edge flight control surface An aircraft wing having a main wing and a trailing edge flight control surface movable between a retracted position, a first extended position in which the control surface is positioned rearwardly in the chord wise direction relative to its retracted position, and a second extended position in which the control surface is rotated relative to its retracted position. A closure panel, mounted to the main wing, extends from the main wing to the control surface, to provide an air flow surface between the main wing and control surface, both when the control surface is in its retracted position and its first extended position. The closure panel is movable, relative to the control surface, to an open configuration in which it opens an airflow passage provided between the control surface and an opposed surface of the aircraft wing when the control surface is in its second extended position.
US12214876B2	Cover panel A cover panel for an aircraft including: a first region, a second region for forming an overlap with a second panel, and a ramp, wherein at least a portion of the ramp is between the first and second regions, wherein the ramp includes a tapered region such that a width of the ramp tapers towards a free-edge of the first region, and wherein the free-edge is configured to form a butt-joint with the second panel.
US12214874B2	Aerial vehicle Aircraft capable of vertical takeoff and landing, hovering, and efficient forward flight are described. An aircraft includes two side mounted tiltable proprotors and a central rotor disposed above the proprotors. The proprotors are tiltable between at least a horizontal position for forward flight and a vertical position for vertical or hovering flight. The central rotor may be powered for vertical and transitional flight modes and may turn by free autorotation during forward flight. The proprotors may be differentially tilted during vertical or hovering flight to counter torque effects of the central rotor. The central rotor may be foldable and/or easily detachable from the aircraft to facilitate storage and transportation. Left and right proprotors may provide both forward thrust and attitude control. Control inputs to left and right proprotors may be connected directly to an autopilot creating closed loop actuation using motor RPM feedback.
US12214869B2	Vibration control assembly A vibration control assembly includes a housing having an interior region and an inner mass including a cage disposed within the interior region of the housing and being rotatable within the housing about a first axis and a gyroscope wheel disposed within the cage and rotatable about a second axis other than the first axis. At least one driving source includes a stator and is operable to interact with a magnetic field of the inner mass to drive rotation of the inner mass about at least one of the first axis and the second axis, wherein the at least one driving source is mounted within the interior region of the housing.
US12214867B2	Aircraft brake control system An aircraft brake control system for controlling anti-skid braking of at least first and second wheels in a wheel set of an aircraft is disclosed. The system includes a control assembly having wheel speed inputs including an input of an indication of the wheel speed of the first wheel, and an input of an indication of the wheel speed of the second wheel, a wheel speed comparator for determining which of the wheel speeds indicated is a lowest wheel speed, and an output for indicating a wheel speed other than the lowest wheel speed. An aircraft landing gear, an aircraft, and methods of braking an aircraft are also disclosed.
US12214859B1	Electrically operated window shade assembly for an aircraft window having opaque and translucent shades An electrically operated window shade system includes a frame that is mounted on the outer side of the inner wall of an aircraft cabin. A cassette is mounted in the frame and includes one or more motors and drive systems and one or two shade elements that are moved between raised and lowered positions under electric control. A user can operate the electric controls to adjust the amount of light coming through the window, as desired.
US12214857B2	Beaded composite structural web An aircraft is described and includes a fuselage; wings attached to the fuselage; and a torque box within the fuselage, the torque box including a side panel, the side panel comprising a composite laminate material including a plurality of stiffening beads integrated therewith.
US12214854B2	Vessel azimuth control apparatus and azimuth control method The objective is to obtain an azimuth control apparatus and an azimuth control method that require no excessive memory capacity and calculation time for information processing and can cope with a disturbance by adaptively adjusting a control gain while calculating changing vessel parameters online. The vessel azimuth control apparatus hasan azimuth control unit that outputs a steering-angle command signal for making a vessel turn to an azimuth to which the vessel should travel, based on an azimuth command signal generated by an azimuth command generation unit, a yaw-angle signal, and a yaw-angular-velocity signal,a steering-angle control unit that controls a rudder based on the steering-angle command signal, anda control gain adjustment unit that calculates respective frequency responses of the yaw-angle signal and the yaw-angular-velocity signal to a steering-angle signal outputted by a steering-angle detection unit and then adjusts a control gain of the azimuth control unit.
US12214850B2	Commissioning strategy A software-based commissioning strategy for customization of a new marine vessel having a newly installed stability/dynamic active control system. The commissioning strategy will be implemented by using a proprietary customer-facing software embedded within a software module of a newly installed dynamic active control system for a new marine vessel (and a new hull type). The software-controlled commissioning strategy is configured to automatically determine the appropriate feedback gains for the marine vessel by controlling the deployment of the water engagement devices while simultaneously measuring and capturing the data generated from the resulting list angle, roll angle, roll rate, and yaw rate changes associated with the deployment. The software driven commissioning strategy is further configured for auto-calibrating the following functional parameters of the new marine vessel: (1) Speed-Based Bias Adjustments (SBBAs), (2) Roll Overall Gain (ROG), (3) Pitch Overall Gain (POG) and (4) Yaw Rate Gain (YRG) of the marine vessel.
US12214847B2	Position control apparatus of unmanned marine observation apparatus and controlling method thereof Provided is a position control apparatus of an unmanned marine observation device, the position control apparatus including a main body part including a hollow portion into which the unmanned marine observation device is coupled, a movement part extending outward from the main body part and configured to move the unmanned marine observation device and the position control apparatus in the ocean, a GPS signal receiver configured to receive a GPS signal and produce position information on the basis of the GPS signal, and a controller configured to control an operation of the movement part on the basis of the GPS signal.
US12214840B2	Removable windscreen arrangement for a tilting vehicle A windscreen arrangement for fastening to a vehicle, in particular to a tilting vehicle, is provided, with a windscreen for at least partially deflecting a headwind during use of the vehicle, and with a securing device for fastening the windscreen to the vehicle, wherein the securing device has at least one connecting portion and at least one latching portion which are each designed for releasably connecting to the vehicle. In addition, a vehicle with a corresponding windscreen arrangement is provided.
US12214834B2	Steering control device A steering control device controls a turning motor that generates a turning force for causing turning wheels of which power transmission to and from a steering wheel is cut off to turn. The steering control device includes a first processor configured to change a steering angle ratio which is a ratio of a turning angle of the turning wheels to a steering angle of the steering wheel according to a vehicle speed through control of the turning motor and a second processor configured to change a degree of change of the steering angle ratio with respect to change of the vehicle speed according to a steering state or a vehicle state.
US12214832B2	Vehicle, method of controlling vehicle, and vehicle control interface box An ADS performs processing including setting an initial value of a wheel steer angle command when an autonomous state has been set to an autonomous mode, obtaining a limitation of a rate, setting a wheel steer angle limitation as the wheel steer angle command when magnitude of the initial value is larger than the wheel steer angle limitation, and transmitting the wheel steer angle command.
US12214831B2	Turning control device A turning control device includes a precursor detection circuit configured to detect a precursor of an abnormality by which a smooth operation of a turning device is impaired. The precursor detection circuit is configured to start measurement of a total running time of a vehicle when the precursor is detected, and is configured to execute a process of reporting the precursor, based on the measured total running time. The precursor detection circuit is configured to perform the measurement of the total running time regardless of whether the precursor is detected again, when a vehicle electric power source is switched off and then is switched on again after the precursor is detected once.
US12214829B2	Current detection device, motor control device, and electric power steering device A current detection device includes a current detection unit configured to detect current flowing through a switching element of a lower-side arm; a correction value calculation unit configured to calculate an offset correction value, based on a detection value of the current detected by the current detection unit in a period during which the switching element off during PWM control, and to hold and update the calculated offset correction value; and a correction unit configured to correct, by the offset correction value held by the correction value calculation unit, the detection value of the current detected by the current detection unit in a period during which the switching element is on. The correction value calculation unit is configured to not update the offset correction value in a case where a duty ratio of the PWM control is equal to or less than a duty ratio lower limit value.
US12214827B2	Exposed structural corner reinforcement The present teachings generally relate to a structural reinforcement, a body member comprising the structural reinforcement, and a method of using the structural reinforcement. The structural reinforcement comprises a first wall, a second wall extending from a first side of the first wall. Spacer legs extend from a second side of the first wall and define a first channel Spacer legs extend from a second side of the second wall and define a second channel. The structural reinforcement is configured to reinforce a joint.
US12214822B2	Trailer assist system with enhanced beam length estimation A vehicular trailering assist system for a vehicle includes a camera disposed at a rear portion of a vehicle and having a field of view exterior and at least rearward of the vehicle, the field of view encompassing at least a portion of a trailer hitched to the vehicle. A control includes a processor for processing image data captured by the camera and sensor data captured by a steering wheel angle sensor and a wheel RPM sensor. The control determines a trailer angle of the trailer relative to the vehicle, a steering wheel angle, and a wheel RPM of a wheel of the vehicle. The control estimates a trailer beam length based on at least the determined trailer angle, the determined steering wheel angle, and the determined wheel RPM.
US12214819B2	Wagon with adapter for installing child seat A seat adapter removably mounts a child seat to a wagon having two opposing walls and an interposed connecting wall, and includes two latch components that mount to the wagon's opposing walls. In some embodiments, the seat adapter includes a cross-member extending between the latch components so that the cross-member provides structural integrity to the wagon if the connecting wall is displaced from its upright use position. In some embodiments, the seat adapter and the child seat can be mounted to the wagon for use with the connecting wall in its upright use position, and in some embodiments the seat adapter and the child seat can be mounted to the wagon for use whether the connecting wall is in its upright use position or its displaced position, with no mechanical interference between any part of the wagon and any part of the adapter or the child seat mounted to it.
US12214815B2	Method and monitoring system for determining a position of a rail vehicle The invention relates to a method for determining a position of a rail vehicle, moving on a track, by means of an optical measuring system comprising a stereo camera system and an evaluation device, wherein by means of the stereo camera system an image pair is recorded from a reference point in a lateral environment of the track and wherein by means of photogrammetry the position of the rail vehicle is determined in relation to the reference point. The position of the rail vehicle is additionally detected by means of a radio-based measuring system for real-time locating by means of anchor modules attached to the rail vehicle and by means of transponders attached to several reference points, wherein position data of the two measuring systems are compared by means of a central system unit. In this way, two independent measuring systems are used to generate position data.
US12214812B2	Vehicle A vehicle, in particular to a rail vehicle, has at least one drive motor and a brake control device. A monitoring device measures, in the braking mode of the vehicle, at least one drive current which flows through the drive motor, and at least one drive voltage which is applied to the drive motor, to form measured values, and to generate operational information which specifies the mode of operation of the drive motor, in particular braking information which specifies a braking effect of the drive motor, on the basis of the measured values.
US12214809B2	Instance segmentation imaging system A method of instance segmentation in an image and a system for instance segmentation of images. The method includes identifying, with a processor, a starting pixel associated with an object in an image, the image having a plurality of rows of pixels, the starting pixel located in a row of the plurality of rows; identifying, with the processor, at least one pixel located in an adjacent row to the row in which the starting pixel is located, the at least one pixel being part of the same object as the starting pixel; iterating the previous two identification steps using the at least one identified adjacent row pixel as a start pixel for the next iteration; and connecting, with the processor, the at least one identified adjacent row pixels to form polylines representing the object.
US12214806B2	Robotic source detection device and method An autonomous robotic vehicle is capable of detecting, identifying, and locating the source of gas leaks such as methane. Because of the number of operating components within the vehicle, it may also be considered a robotic system. The robotic vehicle can be remotely operated or can move autonomously within a jobsite. The vehicle selectively deploys a source detection device that precisely locates the source of a leak. The vehicle relays data to stakeholders and remains powered that enables operation of the vehicle over an extended period. Monitoring and control of the vehicle is enabled through a software interface viewable to a user on a mobile communications device or personal computer.
US12214805B2	Method and device for locating a vehicle in a surrounding area The invention relates to a method for locating a vehicle (1) in a surrounding area, comprising the following steps: providing a primary sensor system (2, 34, 41, 52); providing a secondary sensor system (4, 35, 44, 56), the secondary system being configured in such a manner as to provide a backup to the primary system, the primary sensor system and the secondary sensor system being configured in such a manner as to completely control the vehicle; detecting environment data by means of the primary sensor system and the secondary sensor system; creating maps of the surroundings from the environment data from the primary sensor system and the secondary sensor system by means of a computer system; transferring the maps of the surroundings created from the primary sensor system and the maps of the surroundings created from the secondary sensor system to the computer system; generating at least one plausibility-checked primary sensor system sub-map and at least one plausibility-checked secondary sensor system sub-map by means of the computer system; transferring the plausibility-checked primary sensor system sub-map to the primary sensor system and transferring the plausibility-checked secondary sensor system sub-map to the secondary sensor system; locating the vehicle in the surrounding area by matching the environment data from the primary sensor system with the plausibility-checked primary sensor system sub-map and by matching the environment data from the secondary sensor system with the plausibility-checked secondary sensor system sub-map; comparing the location of the vehicle determined by the primary sensor system with the location of the vehicle determined by the secondary sensor system.
US12214804B2	Vehicle driving control system and vehicle traffic control apparatus A vehicle driving control system includes: a first road-traffic detection information acquisition unit and a first communicator of a mobile body; a road traffic information recognition unit, a control information calculation unit, and a second communicator of a traffic control apparatus; a second road-traffic detection information acquisition unit and a third communicator of a monitoring apparatus; and a driving control execution unit of a vehicle. The first and second road-traffic detection information acquisition units respectively acquire first and second road-traffic detection information. The road traffic information recognition unit recognizes road traffic information from the first and second road-traffic detection information received by the second communicator respectively through the first and third communicators. The control information calculation unit calculates, from the road traffic information, control information for the vehicle. The driving control execution unit controls driving based on the control information received by the first communicator through the second communicator.
US12214801B2	Generating autonomous vehicle testing data through perturbations and adversarial loss functions Techniques for generating testing data for an autonomous vehicle (AV) are described herein. A system can obtain sensor data descriptive of a traffic scenario. The traffic scenario can include a subject vehicle and actors in an environment. Additionally, the system can generate a perturbed trajectory for a first actor in the environment based on perturbation values. Moreover, the system can generate simulated sensor data. The simulated sensor data can include data descriptive of the perturbed trajectory for the first actor in the environment. Furthermore, the system can provide the simulated sensor data as input to an AV control system. The AV control system can be configured to process the simulated sensor data to generate an updated trajectory for the subject vehicle in the environment. Subsequently, the system can evaluate an adversarial loss function based on the updated trajectory for the subject vehicle to generate an adversarial loss value.
US12214800B2	Method of processing data for autonomous vehicle, electronic device, storage medium and autonomous vehicle A method of processing data for an autonomous vehicle, an electronic device, a storage medium, and an autonomous vehicle are provided. The method includes: acquiring sensor data for the autonomous vehicle, wherein the sensor data includes inertial measurement data, LiDAR data, and visual image data; determining a first constraint factor for the inertial measurement data according to the inertial measurement data and the visual image data; determining a second constraint factor for the LiDAR data according to the inertial measurement data and the LiDAR data; determining a third constraint factor for the visual image data according to the inertial measurement data, the visual image data and the LiDAR data; and processing the sensor data based on the first constraint factor, the second constraint factor and the third constraint factor, so as to obtain positioning data for positioning the autonomous vehicle.
US12214796B2	Simulation apparatus and processing load adjustment device In a simulation apparatus for a cockpit system of a vehicle, a driving environment simulation unit performs simulation of a driving environment of the vehicle involving a driving behavior to acquire driving behavior data and generate a travel image as an image simulating scenery visible from the vehicle during travelling. A travel image display unit displays the travel image. A component display unit displays an image of a component generated based on the driving behavior data. A processing load calculation unit calculates a processing load of the simulation apparatus based on at least one of a time difference between acquisition of the driving behavior data and display of the image of the component corresponding to the driving behavior data and a time difference between acquisition of the driving behavior data and display of the travel image generated in response to the driving behavior data.
US12214789B2	Driving support device for vehicle, driving support method for vehicle, and a non-transitory computer-readable storage medium storing a program for causing a computer A driving support ECU (21) of a driving support device (11a) executes automatic deceleration control for decelerating a vehicle (10) without a driver operating a brake pedal (105) when it is determined that a specific condition indicating that the driver intends to turn the vehicle (10) to the right or left at an intersection present in front of the vehicle (10) is satisfied. When a direction indicator (34, 35) stops operating during execution of the automatic deceleration control, the driving support ECU (21) continues the automatic deceleration control until a predetermined time period elapses from a time point at which the direction indicator (34, 35) stops operating, and ends the automatic deceleration control when the direction indicator (34, 35) continues to stop operating from when the direction indicator (34, 35) stops operating until the predetermined time period elapses.
US12214786B2	Method for laterally controlling a motor vehicle on a road having two lanes and motor vehicle Technologies and techniques for laterally controlling a motor vehicle on a road, where a roadway marking assigned to a driver's side of the motor vehicle is assigned to a lane type based on sensor data. The lane type characterizes whether the roadway marking is assigned to an ego lane on which the motor vehicle is to be guided, or whether it is assigned to a neighboring lane adjacent to the ego lane. The roadway marking is also assigned to the lane type, based on swarm data, and the lane type assigned to the roadway marking is established as the lane type that is determined as a function of the swarm data when the sensor lane type and the swarm data lane type diverge. The motor vehicle is laterally controlled as a function of the established lane type of the roadway marking assigned to the driver's side of the motor vehicle.
US12214784B2	Driving assistance control apparatus, driving assistance system, and driving assistance control method for vehicle A driving assistance control apparatus for a vehicle includes an acquiring unit and a control unit. The acquiring unit acquires a detected traveling environment of the vehicle. Using the acquired traveling environment, and in response to a preceding vehicle being present near a road edge and no obstacle being present between the road edge and the preceding vehicle, the control unit causes a driving assisting unit to perform driving assistance in which the preceding vehicle is tracked.
US12214782B2	Ensemble of narrow AI agents for intersection assistance A method for intersection assistance, the method may include obtaining sensed information regarding an environment of the vehicle; determining an occurrence of an intersection related situation, based on the sensed information; generating one or more intersection driving related decisions; wherein the generating comprises processing, by one or more narrow AI agents of a group of narrow AI agents, at least one out of (a) at least a first part of the sensed information, and (b) an outcome of a pre-processing of at least a second part of the sensed information; and responding to the one or more intersection driving related decisions; wherein the responding comprises at least one out of (a) executing the one or more intersection driving related decisions, and (b) suggesting executing the one or more intersection driving related decisions.
US12214778B2	Parking assistance method and parking assistance device A parking assistance method including: detecting a target object position that is a relative position with respect to the own vehicle; retrieving a known target object and a relative positional relationship between the known target object and a target parking position from a storage device; based on the detected target object position detected and a relative positional relationship between the known target object and a target parking position, estimating a relative position of the target parking position with respect to a current position of the own vehicle; based on the estimated relative position, calculating a target travel trajectory from a current position of the own vehicle to the target parking position; determining estimation precision of the estimated relative position; when the estimation precision is low, limiting a speed limit of movement speed at which the own vehicle is caused to travel along the target travel trajectory to a speed lower.
US12214777B2	Parking assist method and parking assist device A parking assist method performs a parking assist control of a host vehicle based on a target travel path when a distance between a self-position and a target parking position is determined to be equal to or less than a first predetermined distance, a parking assist permission condition is satisfied, and a shift operation for switching direction has been detected. The parking assist permission condition is satisfied where either a condition in which a predetermined time or longer has elapsed since the host vehicle departed from the target parking position, or a condition in which the distance between the self-position and the target parking position since the host vehicle departed from the target parking position exceeds a second predetermined distance that is equal to or less than the first predetermined distance. The parking assist control is suppressed when the parking assist permission condition is not satisfied.
US12214772B2	Model predictive control of a motor vehicle A processor unit (3) is configured for executing an MPC algorithm (13) for model predictive control of a motor vehicle (1). The MPC algorithm (13) includes a longitudinal dynamic model (14) of the motor vehicle (1) and a cost function (15) to be minimized. The cost function (15) includes multiple terms, a first term of which represents an output of the cooling pump (28). In addition, the processor unit (3) is configured for, by executing the MPC algorithm (13) as a function of the longitudinal dynamic model (14), ascertaining a speed trajectory of the motor vehicle (1) situated within a prediction horizon and simultaneously ascertaining a pump operating value trajectory situated within the prediction horizon such that the first term of the cost function (15) is minimized.
US12214768B2	Driving force control method and driving force control device A step corresponding control of adjusting driving force of the front wheel motor and driving force of the rear wheel motor when the vehicle passes through a step is executed. In the step corresponding control, after a front wheel ride-up timing at which the front wheel rides up the step and before a rear wheel ride-up timing at which the rear wheel rides up the step, a first control mode in which the front wheel motor is regenerated and the rear wheel motor is powered is executed. In the step corresponding control, after the execution of the first control mode and before the rear wheel ride-up timing, a second control mode in which the front wheel motor is powered and the rear wheel motor is regenerated is executed.
US12214762B2	Supervising device for monitoring the operation of an anti-slip device of a railway braking system A supervising device for monitoring the operation of an anti-slip device is described; the supervising device is arranged to: acquire estimated instantaneous linear speeds associated with axles controlled by the anti-slip device; compare the estimated instantaneous linear speeds with a linear reference speed; monitor the state of the pressures to the brake cylinders; determine whether the anti-slip device is working correctly, depending on predetermined trends of each of the estimated instantaneous linear speeds associated with the axles in the slipping phase, with respect to the reference linear speed, in association with each of the pressures to the brake cylinders associated with the axles adjust the preloaded time value in at least one of the timing devices when the supervising device determines that the anti-slip device is not working correctly.
US12214759B2	Compressor cooling system for cleaning a vehicle sensor Proposed is a compressor cooling system for cleaning a vehicle sensor, the system including: a rainwater sensor unit provided on a front window of a vehicle for detecting rainwater; a rainwater collection unit for collecting the rainwater flowing down to under the front window; a water pump unit connected to the rainwater collection unit for discharging the collected rainwater to an air compressor; and an air compressor cooling unit combined with the air compressor and having an inlet flow path and an outlet flow path inside, the discharged rainwater cooling the air compressor while flowing through the inlet flow path and the outlet flow path.
US12214745B2	Vehicle sensor device and seat belt retractor employing same A vehicle sensor device comprising: a weight body housing installed in a body so as to be rotatable around a shaft coupled to the body, a weight body being installed in the weight body housing, a ball assembly for sensing a change in inclination of a vehicle, a sensor housing in which the ball assembly is movably installed, and a sensor lever installed in the sensor housing and rotated by the movement of the ball assembly. The sensor lever is configured to linearly reciprocate, by rotation, a pilot lever provided in a locking device. The sensor lever is installed in the sensor housing to which the ball assembly is coupled. The sensor lever is rotated around a hinge shaft by the movement of the ball assembly according to a change in inclination of the vehicle to linearly reciprocate the pilot lever connected to the sensor lever.
US12214743B2	Torso seatbelt system A seat includes a seat base including a first side and a second side, and a seat back including a first side portion and a second side portion. The seat back is pivotable between an upright configuration and a highly reclined configuration. A torso belt system is arranged at the seat system. The torso belt system includes a retractor mechanism positioned adjacent to one of the seat base and the seat back. An amount of flexible webbing includes a first end anchored at the retractor mechanism and a second end. A selectable anchor is connectable to the second end of the amount of flexible webbing. The selectable anchor is selectively arranged in a first position at the seat base when the seat back is in the upright seating configuration and in a second position at the seat back when the seat back is in the highly reclined seating configuration.
US12214741B2	Gas generator A gas generator includes a housing main body made of metal, a holder assembly, and an igniter. The holder assembly includes a holder portion made of metal and a connector portion made of resin. The holder portion includes a first barrel portion and an annular projection. The connector portion includes a second barrel portion and a cylindrical portion. The cylindrical portion is inserted in the housing main body and externally attached to the first barrel portion. As a portion of the housing main body corresponding to the cylindrical portion is decreased in diameter, the cylindrical portion is compressed by being sandwiched between the portion of the housing main body decreased in diameter and the first barrel portion so as to seal a gap between the housing main body and the first barrel portion.
US12214736B2	Soft identification plate and method therefor A license plate assembly includes a backing and a flexible license plate. The flexible license plate includes plural layers, including a licensing-information layer, in which ink is deposited in the form of alphanumeric characters on an underlying one of the plural layers, the alphanumeric characters providing license information. The flexible license plate optionally includes one or more holograms, and/or watermarks, and/or QR-codes. The flexible license plate is disposed on the backing, which extends beyond the perimeter of the flexible license plate, defining a marginal region. In some embodiments, plural indices are disposed in the marginal region to facilitate alignment of flexible license plate during installation thereof on a motor vehicle.
US12214732B2	Rear camera triangulation mirror A camera system for a vehicle provides for the generation of different perspectives with a single camera to improve location accuracy. The camera system includes a camera configured for generating an image of an area proximate the vehicle and a mirror mounted proximate the camera and within a field of view of the camera. The mirror provides a secondary view of the area proximate the vehicle to the camera that is included as part of a single image.
US12214731B2	On-board camera device An on-board camera device includes a camera unit, a hood member, a thermally conductive member, a heater device, and a temperature measurement element. The camera unit captures an image of an ambient environment through a window glass of a vehicle. The hood member blocks an unnecessary light beam from outside and suppresses background reflection on the window glass. The thermally conductive member is fixed to the hood member to thermally contact with the window glass. The heater device contacts with the thermally conductive member and removes dew condensation and fog adhering to the window glass. The temperature measurement element is provided at the heater device and partly contacts with the thermally conductive member. The temperature measurement element detects a temperature state of the heater device during operation of the heater device and a temperature state of the window glass through the thermally conductive member during non-operation of the heater device.
US12214730B2	Display system for work machine A bracket for removably coupling a display device with a work machine includes a first member defining a first portion and a second portion spaced apart from the first portion along a longitudinal axis. The bracket also includes a second member coupled to the first member at the second portion thereof. The second member is substantially orthogonal to the first member. The second member defines a third portion and a fourth portion that are spaced apart from each other along a vertical axis that is orthogonal to the longitudinal axis. The bracket further includes at least one coupling element extending from and coupled to the second member at the third portion thereof. The bracket includes at least one projection coupled to the second member at the fourth portion thereof.
US12214728B2	Vehicular exterior rearview mirror assembly A vehicular exterior rearview mirror assembly includes a mirror head accommodating a mirror reflective element, a support structure configured for attachment at a side of a vehicle, and an adjustment mechanism operable to move the mirror head along the support structure between a retracted position and an extended position. A shutoff device includes a base portion and a movable portion movably disposed at the base portion. With the adjustment mechanism operating to move the mirror head along the support structure, the shutoff device stops movement of the mirror head toward the retracted position responsive to the movable portion engaging a first electrical element at a first end region of the base portion, and stops movement of the mirror head toward the extended position responsive to the movable portion engaging a second electrical element at a second end region of the base portion.
US12214722B2	Interior trim article for a motor vehicle An interior trim article for a motor vehicle, comprises a decorative outer skin; a touch-sensor or proximity sensor; and a backlight lighting source disposed behind said touch sensor or proximity sensor to emit light through the touch-sensor and through the decorative outer skin.
US12214714B2	Shipping container fastener and method A fastener for fastening an ISO container to a ship, truck, trailer, another ISO container or other structure. In one embodiment an elongated nut is inserted into an elongated aperture of the ISO container's corner casting, and is rotated 90 degrees to be transverse to the longitudinal axis of the aperture. A threaded shaft is rotated, after being inserted in a slot of a plate mounted to the structure, causing the plate and elongated nut to be drawn closer to one another, thereby clamping the corner casting between the nut and the plate. In another embodiment an elongated nut is inserted into the elongated aperture and is rotated 90 degrees. A line extends from a winch mounted to the structure and is mounted to a loop at the opposite end from the nut. The winch tightens the strap, drawing the loop, nut and, thereby, the container against the structure.
US12214711B2	Expandable wall shelter An expandable wall shelter includes a body and a movable wall section connected to the body and movable between a retracted position and an extended position along a linear path. At least one linkage assembly is operably connected between the body and the movable wall section for operably and movably supporting the movable wall section relative to the body for movement of the movable wall section to and between its retracted and extended positions. The at least one linkage assembly includes: (i) an inner link including opposite inner and outer ends; and (ii) an outer link including opposite inner and outer ends, wherein: the inner end of the inner link is pivotally connected to the body; the said outer end of the outer link is pivotally connected to the movable wall section; and, the outer end of the inner link is pivotally connected to the inner end of the outer link. A linkage assembly for such a movable wall section is also provided.
US12214710B1	Deployable laboratory environment A deployable laboratory environment is disclosed, including a foundation having a movement corridor, and a first and second module that each have a longitudinal axis and a junction side, the junction sides each having at least one opening framed by an interface. The modules are rotatably coupled to the foundation through swivel joints, at least one of which is able to translate along the movement corridor. The modules are movable between travel, intermediate, and deployed configurations. The travel configuration includes the longitudinal axes and the movement corridor being substantially parallel, and the openings being covered. The intermediate configuration includes the longitudinal axes being substantially perpendicular to the movement corridor, the junction sides facing each other, and the openings uncovered. The deployed configuration includes the modules coupled to each other with the interfaces joined and the module interiors combined into compartments which are shielded sufficient to meet an EMC testing standard.
US12214707B2	Seat assembly with massage A seat assembly is provided with a seat frame and a seat support. A plurality of linear actuators or a camshaft are supported on the frame and oriented toward the seat support surface to each provide a localized percussive massage upon the seated occupant. Alternatively, a guide is supported upon the seat frame. A plurality of massage plates is provided on the guide. A plurality of massage nodes is each provided on one of the plurality of massage plates so that compression upon each massage plate flexes a region of each massage plate to extend each massage node forward to provide a localized massage upon the seated occupant.
US12214703B2	Conveyance seat A conveyance seat capable of suppressing wrinkles or saggings from occurring on a surface of a seat main body is provided. A conveyance seat includes a seat back and a movable body which is attached inside the seat back, is disposed at an outer position in relation to a center portion of the seat back, and is operated so that a side portion of the seat back protrudes toward a seated occupant side (seat front side). The movable body is disposed on a back surface of a cushion material in the side portion. An end portion (rear end portion) on the side opposite to the seated occupant side of the movable body is disposed on the seated occupant side (seat front side) in relation to a seating surface of the center portion of the seat back.
US12214700B2	Longitudinal adjuster for a seat and seat A longitudinal adjuster for a seat, in particular vehicle seat, may have at least a fixed lower track and an upper track slidable coupled to the lower track, an adjustment device for longitudinally adjusting the upper track relative to the lower track, a latch mechanism to latch the upper track relative to the lower track, and an electromechanical device relatively coupled to the latch mechanism. The electromechanical device may be configured to bias the latch mechanism between a release position and a latch position, and upon release of the latch mechanism the adjustment device is actuated to drive the upper track relative to the lower track.
US12214699B2	Vehicle seat Provided is a vehicle seat having a variable cushion length. The vehicle seat includes: a front panel of metal arranged on a front-end side of a seat cushion to form a frame of the seat cushion; a sliding device allowing a movable portion to be displaceable and including a sliding member of resin displaceable relative to the front panel in seat front-rear directions; and a bracket of metal that is coupled to the front panel in a manner displaceable relative to the front panel in the seat front-rear directions and that is displaced integrally with the sliding member, the bracket transmitting a load acting on the movable portion to the front panel.
US12214695B2	Vehicle battery management system The present disclosure provides a vehicle battery management system. In a vehicle battery management system including a battery unit configured to supply power to an electric vehicle, and a controller configured to control the battery unit, the battery unit is divided into a first battery unit and a second battery unit, the first battery unit supplies power to a motor for generating driving force of the electric vehicle, the second battery unit supplies power to an outside of the electric vehicle, the controller performs a control operation so that power supplied from the first battery unit is supplied to the outside of the electric vehicle or power supplied from the second battery unit is supplied to the motor based on an SOC of each of the first battery unit and the second battery unit and state information of the electric vehicle.
US12214690B2	Electric meter The invention relates to an electric meter (1) for measuring the electric consumption of an electric load (RLOAD), in particular while charging an electric vehicle. The electric meter according to the invention has a current measuring device (11) in order to measure a charging current (ILOAD) which flows through a charging cable (7) to a transfer point (9, 10) for the load (RLOAD), wherein the transfer point (9, 10) is preferably located in a plug (8) of the charging cable (7). Furthermore, the electric meter (1) according to the invention includes a voltage measuring device (12) for measuring a voltage. According to the invention, the voltage measuring device (12) measures the voltage directly at the transfer point (9, 10) of the charging cable (7) in order to determine line losses in the charging cable (7), in particular in order to take into consideration the line losses when calculating the consumption.
US12214689B2	Method for controlling charging of electrical storage devices A method for controlling charging of at least one electrical storage device is disclosed. Information regarding a power grid and the at least one electrical storage device is used by an aggregator to derive a weighted distribution of virtual inertia response and fast frequency response to be provided to the power grid by the electrical storage devices. A total power available for charging the at least one electrical storage device is derived in accordance with the weighted distribution by a charging controller. An active power setpoint is derived for each of the at least one electrical storage device on the basis of at least (i) the total available power and (ii) the information regarding the at least one electrical storage device. Finally, a charging state of each of the at least one electrical storage device is controlled based on the derived active power setpoint.
US12214688B2	Control units, systems, and methods for establishing reserve power limits Various disclosed embodiments include illustrative control units, systems, and methods. In an illustrative embodiment, a control unit includes a processor and computer-readable media that stores computer-executable instructions. The instructions cause the processor to establish a reserve level for a battery of a first device. The reserve level provides sufficient electrical power to enable the device to achieve a function. The instructions further cause the processor to enable the battery to function as a power supply configured to provide electrical power for a second device external to the first device responsive to a power level of the battery exceeding the reserve level and to disable use of the battery as the power supply for the second device responsive to the power level of the battery being below the reserve level.
US12214681B2	Tire/wheel assembly and tire A tire/wheel assembly includes a wheel including a disk and a rim, the wheel having a power reception device attached to an inner peripheral surface of the rim to receive electric power supplied wirelessly from farther outward in a radial direction of the wheel than the rim, and a tire attached so as to cover an outer peripheral surface of the wheel and including a pair of bead portions. Each bead portion in the pair of bead portions includes a bead core and a bead filler, and 0.1≤BFW/BDW≤0.6, where BFW is a width in a tire width direction at a central position of the bead filler in a tire radial direction, and BDW is a maximum width in the tire width direction of the bead core.
US12214680B2	Method for arranging inductive chargers in a warehouse, system having an arrangement of inductive chargers, and an industrial truck for a warehouse A method for inductively charging one or more inductively chargeable industrial trucks used in a warehouse, wherein a target value is determined for an average charging time of each of the industrial trucks used in the warehouse and distributing a plurality of inductive charger in the warehouse such that at least one of the industrial trucks can be inductively charged in accordance with at least with the target value.
US12214674B2	Method for detecting an insulation fault in a vehicle on-board electrical system and vehicle overvoltage protection circuit A method for detecting an insulation fault in a vehicle on-board electrical system having an HV and LV on-board electrical system branches. The LV branch has at least one first LV potential and a second LV potential that differs therefrom and corresponds to a ground potential of the vehicle on-board electrical system. The HV branch has positive HV negative HV potentials. These HV potentials are DC-isolated from the LV branch potentials. An insulation fault between at least one of the HV potentials and the first LV potential is detected by identifying a current flow. The current flow runs through a voltage limiting circuit connected between the ground potential and the first LV potential. This circuit connects the first LV potential, via a plurality of diodes, to a voltage limiting element connected to the ground potential of the vehicle on-board electrical system. A vehicle overvoltage protective circuit is also described.
US12214673B2	Electrical circuit based voltage control of electric vehicle batteries Voltage control of electric vehicle batteries is provided. A system can include an electrical circuit of an electric vehicle that can include a plurality of power supplies and a driver component that can be configured to be energized by the plurality of power supplies and provide a voltage greater than a threshold from a battery of the electric vehicle to a motor of the electric vehicle. The electrical circuit can include a switch module that connects the driver component with the plurality of power supplies. The switch module can detect that the electric vehicle generated a signal to actuate an element of the electric vehicle and disconnect, in response to the detection, the driver component from the plurality of power supplies to reduce the voltage provided to the motor below the threshold.
US12214671B2	Rotary permanent magnet electrodynamic suspension device and permanent magnet electrodynamic suspension method using the same A rotary permanent magnet electrodynamic suspension device includes drive systems, a suspension system, an isolation layer. The drive systems are symmetrically provided in an axial direction of the suspension system. The isolation layer is provided between the suspension system and each drive system. The suspension system includes a magnetic wheel, a non-magnetic conductor and a support. The non-magnetic conductor has electromagnetic induction with the magnetic wheel. The support and the magnetic wheel are both ring-shaped, and the magnetic wheel is sleeved on an outer circumference of the support. The drive systems are configured to drive the magnetic wheel to rotate through electromagnetic induction. The magnetic wheel includes an annular array of permanent magnets to form four pole pairs based on radial magnetization and tangential magnetization. A permanent magnet electrodynamic suspension using the device is also provided.
US12214666B2	Vehicle driving apparatus A vehicle driving apparatus is provided that includes a drive motor, an internal combustion engine, and an electrical generator and can inhibit a weight balance and motion performance of a vehicle from being deteriorated and lowered. A vehicle driving apparatus driving a vehicle by motive power of a motor, the vehicle driving apparatus including a drive motor that is driven by electric power, an internal combustion engine that produces motive power by fuel, and an electrical generator that is driven by the internal combustion engine, the vehicle driving apparatus being characterized in that the drive motor, the internal combustion engine, and the electrical generator are arranged in a vehicle width direction of the vehicle in order of the drive motor, the internal combustion engine, and the electrical generator.
US12214661B2	Question-and-answer system and method of controlling the same A question-and-answer system providing an appropriate answer for a vehicle-related FAQ by using deep learning, and corresponding method are provided. The question-and-answer system includes: a memory that stores a plurality of representative questions to match a plurality of answers corresponding to the plurality of representative questions, respectively; a learning module configured to output a representative question corresponding to an input sentence from among the stored plurality of representative questions; and an output module configured to search the memory or an answer that matches the output representative question and output the found answer. The learning module is configured to perform multi task learning using a plurality of extended sentences for the plurality of representative questions as input data, and using the plurality of representative questions corresponding to the plurality of extended sentences, respectively, and a plurality of categories to which the plurality of extended sentences belong, respectively, as output data.
US12214659B2	Power take-off (PTO) assembly in a transmission and PTO assembly operating method Power take-off (PTO) systems and methods. A PTO assembly, in one example, includes a first one-way clutch configured to engage with a shaft of a prime mover or an output shaft when the prime mover rotates in a first direction and a second one-way clutch configured to engage with the shaft of the prime mover or the output shaft when the prime mover rotates in second direction which is opposite the first direction. The PTO assembly further includes a first mechanical branch rotationally coupling the first one-way clutch to the output shaft or the prime mover shaft and a second mechanical branch rotationally coupling the second one-way clutch to the output shaft or the prime mover shaft.
US12214656B2	Charging door assembly or tank door assembly of a motor vehicle, and motor vehicle A charging or tank door assembly of a motor vehicle, including a base body receiving a charging socket or a tank inlet, a door body pivotable about an axis of rotation and supporting a panel body on a first position, and a push-push mechanism for locking the door body and releasing the door body in the first position. In the first position, the door body closes an opening in a body of the motor vehicle and blocks access to the charging socket or to the tank inlet. In a second position, the door body releases the opening of the body of the motor vehicle and the access to the charging socket or to the tank inlet. Relative to the first position, the push-push mechanism is arranged on a different side of the axis of rotation than the first portion, supporting the panel body, of the door body.
US12214655B2	Tank assembly A tank assembly includes a tank, at least one pressure relief valve, at least one heat transmission path, and at least one heat transmission element. The at least one pressure relief valve is configured to allow a pressure relief of the tank when a temperature threshold value at the pressure relief valve is exceeded. The heat transmission path and the pressure relief valve are connected via the at least one heat transmission element. The heat transmission element is changeable with respect to the heat transmission between the heat transmission path and the pressure relief valve.
US12214653B2	Vehicle including air inflow adjustment mechanism A vehicle includes an outside-air intake and an air inflow adjustment mechanism. The outside-air intake is configured to take outside air into an internal chamber of the vehicle. The air inflow adjustment mechanism is configured to adjust a flow rate of air that is to flow into the outside-air intake. The air inflow adjustment mechanism is disposed at the outside-air intake and includes one or both of a positive pressure source configured to perform discharge of gas and a negative pressure source configured to perform suction of gas.
US12214650B2	Systems for drive axle Methods and systems are provided for an electric drive axle. In one example, a tube is pressed into a portion of a differential housing, wherein a mount, a reinforcement ring, a wheel hub assembly, and a brake housing are physically coupled to the tube. The tube defines an axle path of an electric drive axle from an electric motor to a wheel.
US12214648B2	Hybrid composite tailgate The invention relates to a hybrid tailgate for a vehicle, comprising a thermoplastic inner structure forming the carrier frame of the tailgate, and at least one composite reinforcement part to reinforce the carrier frame, wherein the composite reinforcement part is connected to the thermoplastic inner structure at a first surface, wherein the composite reinforcement part forms a continuous load path in the inner structure enclosing a tailgate window opening for a window glazing part of the tailgate. Furthermore, the invention relates to a vehicle comprising such a hybrid tailgate. Moreover, the invention relates to a method of manufacturing such a hybrid tailgate, the method comprising forming a composite laminate part into an insert; placing the insert in an injection molding tool; and over-molding the insert with polymer resin.
US12214647B2	Vehicle electric fluid machine A vehicle electric fluid machine includes: a housing provided with a mounting leg having an insertion hole; a fastener having a shaft portion inserted into the insertion hole and a head portion at one end of the shaft portion, the fastener fastening the other end of the shaft portion to a mounting object; a sleeve disposed between the mounting leg and the shaft portion, elastic vibration dampers disposed on opposite sides of the mounting leg in its axial direction, each of the elastic vibration dampers having a cylindrical portion disposed between an inner circumferential surface of the mounting leg and an outer circumferential surface of the sleeve, and a collar extending from one of opposite ends of the cylindrical portion in a radial outward direction of the cylindrical portion; and an annular plate through which the fastening force is applied to the mounting leg through the collar.
US12214646B2	Cooling system A cooling system for a vehicle may include a cooling circuit through which a coolant is flowable. The cooling circuit may include a first heat source, a first radiator, a second heat source, a second radiator, and a hydraulic switch. The first heat source may be coolable at a lower temperature level. The second heat source may be coolable at a higher temperature level. The first heat source, the first radiator, the second heat source, and the second radiator may be connected in series with one another in the cooling circuit. The hydraulic switch may divide the cooling circuit into (i) a first partial circuit with the first heat source and the first radiator and (ii) a second partial circuit with the second heat source and the second radiator.
US12214643B2	System and method for determination of required environmental conditions for transport and storage of goods A system, for determination of required environmental conditions for transport and storage of goods, that includes one or more boxes to be placed in a vehicle. Each box has an indicator code, on the exterior surface of the box, that includes information related to environmental conditions required to be maintained. A scanning device associated with the vehicle and configured to read said indicator code from each box. A control circuitry is operationally connected to the scanning device The control circuitry is configured to compute the readings of the indicator codes from each box to determine the required environmental conditions to be maintained inside the vehicle.
US12214640B2	Pneumatic adjustment apparatus and method for vehicle Disclosed herein is a pneumatic adjustment apparatus for a vehicle. The pneumatic adjustment apparatus includes a block including a flow path formed therein, the flow path being configured for a fluid to move through the block, a compressor coupled to the block and configured to communicate with the flow path and to compress the fluid, a driver coupled to the block, connected to the compressor, and configured to drive the compressor, and a controller coupled to the block and configured to open and close the flow path.
US12214638B2	Vehicular torsion beam axle A vehicular torsion beam axle includes a torsion beam, a pair of trailing arms connected to both ends, respectively, of the torsion beam; a pair of mounting pipes connected to the pair of trailing arms, respectively, each of the mounting pipes including a separation prevention protrusion, and a bushing press-inserted into each of the mounting pipes. Each of the bushings has a separation prevention groove in which the separation prevention protrusion of one of the mounting pipes is engaged.
US12214637B2	Spacer element system for an automotive suspension system A spacer element system for a vehicle suspension system, includes a receiver configured to be attached to a suspension component of the vehicle suspension system, and a spacer that is removably connected to the receiver. A vehicle suspension system includes a spring and the spacer element system, wherein the receiver is attached to the spring.
US12214636B2	Amphibious vehicle An amphibious vehicle having a frame that includes a plurality of floatable members. Mounted to the frame is one or more power sources. Also mounted to the frame and connected to the power source are a plurality of propellers with each of the plurality of propellers having a thrust vector configured to be adjusted to provide agitation and propulsion. In addition, mounted to the frame are a plurality of ground engaging devices and one or more pumps.
US12214635B2	All-terrain vehicle An all-terrain rover is provided in which the arrangement of flanges of one or more cylinders of first and second cylinder systems allow for forward and backwards motion, as well as turning and sideways motion of the roller. An all-terrain rover is further provided in which the flanges of the first cylinder system are oriented opposite to an orientation of the flanges of the second cylinder system such that, in counter-rotation, a forward or reverse motion results from contact between the flanges and a surface of travel. An all-terrain rover is further still provided in which the flanges of a first cylinder of the first cylinder system is oriented in an opposite orientation to the flanges of a second cylinder of the first cylinder system and the orientation of a first cylinder of the second cylinder system is oriented in an opposite orientation to the flanges of a second cylinder of the second cylinder system such that each cylinder can be rotated in an individual direction and individual speed to create forward and backwards motion along the axis of the cylinders as well as steerable motion.
US12214634B2	Towing cap and bumper cover of vehicle having same A bumper cover of a vehicle includes a cover frame and a towing cap. The cover frame includes: a hook hole through which a hook configured to tow a vehicle body passes; and an installation hole disposed near the hook hole. The towing cap includes: a cap part configured to open and close the hook hole; and an anchor part protruding outward from the cap part in a bent shape and fixedly inserted into the installation hole. The towing cap is out of contact with the hook in a configuration in which the cap part opens the hook hole.
US12214633B1	Trailer hitch with lift mechanism A trailer hitch with lift mechanism includes a vehicle connection point, an adjustable hitch base, a motor, and a hitch locking assembly. The motor is powered via a trailer hitch plug of a towing vehicle. The adjustable hitch base includes a plurality of adjustment apertures and one or more guide tracks. The hitch locking assembly is slidingly coupled to the adjustable hitch base and includes one or more guide rollers slidingly associated with the guide tracks, a backing plate, an aperture configured to receive a ball, and one or more adjustment locking devices. Rotation of the drive shaft causes the hitch locking assembly to move relative to the adjustable hitch base.
US12214630B2	Control device, tire inflation system including said control device, and methods of operating said tire inflation system The present document relates to a control device for a central tire inflation system, comprising: an inlet for connection with a pressure source, at least a first outlet for connection with a first pneumatic tire, a supply valve, at least a first channel valve, and at least a first pressure-limiting valve, wherein the supply valve and the first channel valve selectively fluidly connect the inlet to the first outlet and are fluidly connected in series between the inlet and the first outlet, and wherein the first pressure-limiting valve is fluidly connected to the first outlet for limiting a pressure at the first outlet. The present document further relates to methods of operating the control device for the central tire inflation system.
US12214629B2	Pneumatic tire Provided is a pneumatic tire. A band-like sound absorptive member is fixed to the inner surface of a tread portion along the tire circumferential direction. An end portion in the tire width direction of the sound absorptive member is located on the outer side in the tire width direction with respect to a shoulder main groove located on the outermost side in the tire width direction. A width W1 of the sound absorptive member in the tire width direction and a tread development width TDW of the tread portion satisfy a relationship of 0.65≤(W1/TDW)≤0.90. The width W1 of the sound absorptive member and a belt width W2 of a first belt ply having the maximum width of a belt layer satisfy a relationship of 0.70≤(W1/W2)≤0.95.
US12214625B2	Wear-condition-sensing device A wear-condition-sensing device includes an element configured to generate voltage based on deformation of a tread portion during tire rotation, a voltage detection unit configured to detect the voltage generated by the element, a storage area configured to store waveform data over time of the voltage detected by the voltage detection unit, a calculation unit configured to calculate an index value of voltage change based on the waveform data stored in the storage area, and a determination unit configured to determine a progress condition of wear of the tread portion by comparing the index value calculated by the calculation unit with reference information.
US12214624B2	Pneumatic tire A tread portion of a pneumatic tire includes: an intermediate land portion being delimited by an inner circumferential main groove and an outer circumferential main groove on one side in a tire lateral direction across a tire center line as a boundary; and a side land portion adjoining the outer circumferential main groove and being provided outward of the outer circumferential main groove in the tire lateral direction. At least one land portion of the intermediate land portion and the side land portion has a swelling profile line. In a region of the land portion, a composite sipe is provided. In the composite sipe, a first sipe extending linearly in a sipe depth direction and a second sipe (S2) extending in a wave manner in the sipe depth direction are connected. The second sipe in the composite sipe is disposed so as to be connected to the outer circumferential main groove.
US12214621B2	Pneumatic tire A tread pattern of a pneumatic tire includes a pair of circumferential grooves and a plurality of siped lug grooves extending in a tire width direction between the pair of circumferential grooves and disposed at intervals in the tire circumferential direction. Each of the siped lug grooves includes a lug groove extending from a first circumferential groove of the pair of circumferential grooves and closed, and a sipe extending from a closed end of the lug groove toward a second circumferential groove and connected to the second circumferential groove. The plurality of siped lug grooves include at least one first siped lug groove extending while bending with an extension direction of the lug groove differing from an extension direction of the sipe, and at least one second siped lug groove extending linearly with the extension direction of the lug groove aligning with the extension direction of the sipe.
US12214619B2	Roller device with eccentric wheel axle A rolling device having a bearing housing accommodating a wheel axle, a drive motor with first and second motor parts for conduction of relative rotation between a wheel element and the wheel axle, end portions of the wheel axle being connected to axle support members in an eccentric position displaced from the center line of the axle support members, and locks operable between an unlocked position allowing rotation of the axle support members relative to the bearing housing, and a locking position preventing the rotation of the axle support members, wherein in the unlocked position, the motor conducts rotation of the axle support members and wheel axis for displacement of the wheel element by an eccentric movement between an extended position where at least a portion of the wheel element projects outside the bearing housing and a retracted position where the wheel element is located inside the bearing housing.
US12214617B2	Biodegradable marker pen A biodegradable marker pen including a barrel, a cap, and an ink reservoir. The barrel has a hollow cylindrical structure, the ink reservoir is placed in the barrel, and the cap is detachably coupled with the barrel hermetically. The barrel, the cap, and the ink reservoir comprise 2 to 10 mass percentage of a biodegradable masterbatch respectively.
US12214616B2	Mechanical pencil A mechanical pencil includes a ball chuck, a rotation drive mechanism having a rotary part, a feedout cam face having a step part in the axial direction, an input member rotating upon receiving a rotational drive force of the rotary part, and an output member having an abutting part abutting against the feedout face and a slider provided with a holding chuck holding lead, the abutting part moves along the feedout face corresponding to rotation of the output member and so that advancing motion of the slider when the abutting part drops into the drop difference causes lead held by the holding chuck to be pulled out by the ball chuck, and further including a clutch mechanism transmitting rotational movement of the input member to the output member.
US12214612B2	Method of designing a light-redirecting surface of a caustic layer, an optical security element comprising the designed light-redirecting surface of the caustic layer, a marked object, use and method of authenticating the object The invention relates to a method of designing a refractive transparent or partially transparent light-redirecting surface, or a reflective light-redirecting surface, of a caustic layer comprising providing a discrete representation of an input target image, calculating a generalized power diagram for a set of image pixels pi of the target image and computing a piecewise light-redirecting surface of the caustic layer based on a calculated optimal set of weights minimizing a cost function associated with the set of image pixels pi. The invention also relates to an optical security element, a marked object, a method of visually authenticating an object and use of the optical security element for authenticating or securing against counterfeiting.
US12214608B2	Methods and systems for laser marking pharmaceutical capsules during manufacturing A method is provided for applying a laser marking to a sheet of material forming a capsule from portions of the sheet of material using a pair of die rollers wherein the location of the laser marking is established such that it does not overlap at least one of a seal between the pair of sheets of material formed during the formation of the capsule.
US12214607B2	Image recording method Provided is an image recording method including applying a pretreatment liquid containing water and a resin X and an ink containing water and a colorant onto a resin base material A which has a specific distortion rate and to which a tension is applied, to obtain an image, heating the image to a temperature Td and drying the image, and cooling the image to a temperature Tr, in which σtotal calculated by Equation (1) is 40 kgf/cm2 or less. E(Td) represents an elastic modulus of the resin X at the temperature Td, ε(Td) represents an expansion coefficient of the resin base material A under specific conditions, E(T) represents an elastic modulus of the resin X at a temperature T of the image in the cooling, αr(T) represents a linear expansion coefficient of the resin X at the temperature T, and αs(T) represents a linear expansion coefficient of the resin base material A under specific conditions. σ total =  σ dry + σ cool  Equation ⁢ ⁢ ( 1 ) σ dry = E ⁡ ( T d ) ⁢ ⁢ ɛ ⁢ ⁢ ( T d ) Equation ⁢ ⁢ ( 2 ) σ cool = ∫ T r T d ⁢ E ⁡ ( T ) ⁢ ( α r ⁡ ( T ) - α s ⁡ ( T ) ) ⁢ dT Equation ⁢ ⁢ ( 3 )
US12214606B2	Printing system, operation system, printer, and terminal A printing system includes a printer and a terminal capable of wirelessly communicating with each other. The printer include a portable printer main body, a movement detection unit that detects a movement of the printer main body, and a first processor configured to transmit a first control signal to the terminal in a case where a first movement is detected by the movement detection unit, and transmit a second control signal to the terminal in a case where a second movement is detected by the movement detection unit. The terminal includes a display unit, a second processor configured to receive the control signals from the printer; and display a first operation screen on the display unit in a case where the first control signal is received, and display a second operation screen on the display unit in a case where the second control signal is received.
US12214604B2	Image formation device, control method for image formation device, and cartridge An image forming apparatus has a main body housing, a network interface for connecting to a network, a cartridge mountable to the main body housing and having a material or a component to be used for image formation in the image forming apparatus and a memory that stores contract information for permitting use of the cartridge in the image forming apparatus set to a contract mode, a communication unit for performing communication with using a mobile network different from the network, and a controller. The controller acquires the contract information from the memory, in a state where the cartridge is mounted to the main body housing, permits printing in the image forming apparatus using the cartridge based on the contract information, and transmits information about the image forming apparatus or the cartridge regarding the contract mode to a communication apparatus via the communication unit.
US12214600B2	Liquid discharging head, liquid discharging unit, and device for discharging liquid A liquid discharging head includes a nozzle plate having a plurality of nozzles from which liquid is discharged; a plurality of individual liquid chambers that are communicably connected to the plurality of nozzles, respectively; a common liquid chamber that supplies liquid to the plurality of individual liquid chambers; and a circulation common liquid chamber that leads to a plurality of circulation channels. A part of the common liquid chamber overlaps the circulation common liquid chamber from a direction in which liquid is discharged from the nozzles, and another part of the common liquid chamber overlaps the circulation common liquid chamber from a direction orthogonal to both the direction in which liquid is discharged from the nozzles and a direction in which the nozzles are aligned.
US12214598B2	Fluid extraction via removable extraction reservoirs In one example in accordance with the present disclosure, a fluid extraction system is described. The fluid extraction system includes an interface to fluidically and electrically couple a removable extraction reservoir to a printing device. The removable extraction reservoir is to receive an amount of fluid from a reservoir in the printing device. The system also includes a controller to, based on data received from memory of an interfaced removable extraction reservoir, initiate an extraction operation wherein fluid from the reservoir is passed to the removable extraction reservoir.
US12214592B2	Liquid discharge apparatus and method of driving liquid discharge head A liquid discharge apparatus includes a diaphragm, a pressure chamber substrate including a partition wall partitioning a pressure chamber communicating with a nozzle discharging liquid, a piezoelectric element including a first active portion that overlaps a center of the pressure chamber and a second active portion that overlaps the pressure chamber at a position closer to an outer edge of the pressure chamber than the first active portion, and a drive signal generation portion that generates a discharge signal for discharging the liquid by being supplied to one of the first active portion and the second active portion and a correction signal that is supplied to the other of the first active portion and the second active portion, in which a potential of the discharge signal changes over time and a potential of the correction signal is constant during a discharge period for discharging the liquid.
US12214589B2	Indirect printing system An indirect printing system is disclosed having an intermediate transfer member (ITM) in the form of an endless belt that circulates during operation to transport ink images from an image forming station. Ink images are deposited on an outer surface of the ITM by one or a plurality of print bars. At an impression station, the ink images are transferred from the outer surface of the ITM onto a printing substrate. In some embodiments, the outer surface of the ITM 20 is maintained within the image forming station at a predetermined distance from the one or each of the print bars 10, 12, 14 and 16 by means of a plurality of support rollers 11, 13, 15, 17 that have a common flat tangential plane and contact the inner surface of the ITM. In some embodiments, the inner surface of the ITM is attracted to the support rollers, the attraction being such that the area of contact between the ITM and each support roller is greater on the downstream side than the upstream side of the support roller, referenced to the direction of movement of the ITM.
US12214588B2	Drying ink in digital printing using infrared radiation A system includes (a) an image forming station including multiple print bars arranged along an axis and configured to apply to a substrate being moved along the axis, droplets of printing fluids having multiple colors, respectively, and (b) multiple dryers, which are mounted on the image forming station, and are interleaved with the multiple print bars along the axis, the multiple dryers are configured to dry the droplets applied to the substrate for forming an image on the substrate, at least a dryer among the dryers includes: (i) an illumination assembly, which is configured to dry the droplets by directing the optical radiation to impinge on the substrate, and (ii) a temperature control assembly, which is configured to control a temperature of the substrate by directing a gas to the substrate, the illumination assembly and the temperature control assembly are packaged together in a housing.
US12214587B2	Cartridge A cartridge configured to be mounted on a tape printer, the cartridge including a cartridge case, in which the cartridge case is provided with a tape feed port through which a tape fed from an accommodated tape roll is fed out of the cartridge case, a tape insertion port into which the tape is configured to be inserted in a first direction from one end portion in a width direction of the tape, and a tape guide that is positioned in the first direction with respect to the tape insertion port and guides feeding of the tape by the tape printer, the tape guide is provided with a protruding portion that comes into contact with the tape, and a tape guide chamfered portion is provided at an end portion of the protruding portion in a second direction opposite to the first direction.
US12214579B2	Dry film lamination with dynamic feedback control The present disclosure is directed to a position-controlled lamination tool or press that includes an array or plurality of pressure sensors and an array or plurality of heating/cooling elements or components, which may be coupled together, for preventing or reducing laminating film or material bleed out and improving thickness variation performance. The pressure sensors may provide a controller, which is coupled to the lamination tool, with real-time feedback on any thickness variations across a substrate panel and the controller may adjust the temperature output of the heating and cooling elements to locally modify the viscosity of the laminating material in one or more regions of the substrate panel to either decrease or increase the flowability of the laminating material.
US12214574B2	Barrier film substrate, method of making same, and use thereof A barrier film substrate includes a first layer including a polymer and a transition metal having chemical sequestering properties such that, upon exposure of the barrier film substrate to one or more chemical vapors, a reaction occurs between the transition metal and the one or more chemical vapors. A second layer is aligned with the first layer. The second layer includes a polymer having impeding properties such that, upon the exposure of the barrier film substrate to the one or more of the chemical vapors, the second layer substantially blocks passage of the one or more of the chemical vapors through the barrier film substrate. One or more additional layers is aligned with at least one of the first layer or the second layer to provide structural support for the first layer and the second layer.
US12214567B2	Press machine having planetary gear system for multi-speed drive functionality A press machine for forming a part comprises a planetary gear system, a first motor, a second motor, a linear actuator, and a press ram that holds a tool. The planetary gear system includes a ring gear, a sun gear, and a plurality of planet gears between the sun gear and the ring gear. The planetary gear system has an output shaft that is coupled to the linear actuator. The first motor is coupled to the planetary gear system for producing a high-speed condition on the linear actuator and the press ram. A second motor is coupled to the planetary gear system for producing a high-torque condition on the linear actuator and a corresponding high-force condition the press ram. The press ram forms the part with the tool during the high-force condition.
US12214566B2	Method for manufacturing a cushion and cushion The invention relates to a method for producing a cushion for an orthopedic device, the cushion having at least one fluid-filled volume, wherein the method includes compression molding of a three-dimensional first cushion component made of at least a first material, which is preferably elastic, in a mold that comprises an inner mold and an outer mold, and bonding the first cushion component to at least a second cushion component in such a way that the fluid-filled volume is created.
US12214565B2	Pneumatic tire and method of manufacturing the same A pneumatic tire that is vulcanized using a bladder provided with a coating layer formed by a release agent, a noise absorber 6 being fixed on an inner surface of a tread portion 1 along a tire circumferential direction via an adhesive layer 7, and a thickness of the release agent detected by an electron microscope is 0.1 μm to 100 μm at least in a fixation region for the noise absorber 6.
US12214561B2	Tape deposition head A tape deposition head for applying lengths of tape to a deposition surface, the tape deposition head comprising: a tape cutter having a tape inlet and a tape outlet, the tape cutter comprising: a feed roller configured to drive the tape though the tape cutter from the tape inlet to the tape outlet along a tape path; a nip roller acting against the feed roller to press the tape against the feed roller; and a tape slicer, the tape slicer having a blade for cutting the tape into lengths, the tape slicer being positioned between the feed roller and the tape outlet along the tape path; and a tape conveyor positioned at the tape outlet, the tape conveyor comprising: a deposition roller remote from the tape outlet; a capture roller; a vacuum chamber; and a belt that runs between the capture roller and the deposition roller, the capture roller being positioned proximal to the tape outlet so that tape exiting the tape outlet contacts the belt, the belt being configured to move a cut length of tape to the deposition roller along a capture surface of the tape conveyor for deposition of the length of tape on to the deposition surface, the vacuum chamber generating a variable level of vacuum along the capture surface to hold the length of tape to the belt.
US12214559B2	Pipe forming apparatus According to the present invention, there is provided a pipe forming apparatus for forming a pipe at an installation site. The apparatus includes a former upon which material is wound, and a mold for receiving the former bearing the wound material. An applicator is provided for applying curable liquid within the mold. Advantageously, the pipe is formed at site to provide for efficient formation of a pipeline. A transported ISO container providing the material and curable liquid to the site can produce 800 metres of pipeline section, compared with 60 metres in the prior art, representing a significant increase in efficiency.
US12214558B2	Core and method of forming structural body A core according to one aspect of the present disclosure is a core that is inserted into a space between a skin and a stringer in a step of integrally molding the skin and the stringer, the skin including fiber-reinforced resin, the stringer having a hat-shaped section that is open toward the skin. The core includes: a first die that extends along a longitudinal direction of the stringer and contacts the skin; a second die that extends along the longitudinal direction of the stringer, is adjacent to the first die, and contacts the skin; and a third die that extends along the longitudinal direction of the stringer, is located at an opposite side of the skin across the first die and the second die, and contacts both the first die and the second die.
US12214557B2	Weldable connecting element for connecting or joining thermoplastic line elements, and a welding assembly and a method for producing a welded connection The invention relates to a weldable connecting element 2 for connecting or joining thermo-plastic line elements 3. The connecting element 2 comprises: a thermoplastic body 4; at least one heating element 6, which is embedded in the body 4, wherein the heating element 6 serves to generate heat in a welding area 5 for welding the body 4 to the at least one line element 3. Furthermore, a joining control 12 is provided, which is configured to prohibit the welding operation and/or to interrupt the welding operation if the body 4 and the line element 3 are not joined correctly.
US12214552B2	Filament feeding adjustment device A filament feeding device (100) for use in 3D-printing comprising a first feeding wheel (110) configured to rotate with a first rotational shaft (112) and a second feeding wheel (120) configured to rotate with a second rotational shaft (122). The first and second feeding wheels (110, 120) are separated by a separation distance so as to allow feeding of a filament material received between said first and second filament wheels (110, 120). The filament feeding device further comprises an adjuster element (130) movable between a first distinct position (130a) setting said separation distance to a first predetermined distance, and into a second distinct position (130b) setting said separation distance to a second predetermined distance, and wherein said second predetermined separation distance is larger than said first predetermined separation distance. Further, a 3D-printer comprising such a filament feeding device is herein disclosed.
US12214550B2	System and method for facilitating separation of stereolithography 3D-printed objects from build platforms A system and method for facilitating separation of 3D-printed objects from build platforms. The principle of separation in the present invention involves a build platform configured to be removable or flexible or partially deformable, such that at least a portion of the build platform may be bent or tilted to separate the build platform from the 3D-printed object once the 3D-printing is completed. In some embodiments, a base assembly is adapted to magnetically move a build plate along a surface of the base assembly such that the build plate automatically self-aligns along a boundary of the base assembly and magnetically couples to the base assembly. In some embodiments, a build platform includes a flexible layer with a printable surface and a rigid layer coupled to the flexible layer so that applying a force on the flexible layer deforms a localized portion of the printable surface without deforming the rigid layer.
US12214548B2	Processes for producing a shaped body using polyamide blends containing a polyarylether The present invention relates to a process for producing a shaped body by selective laser sintering of a sinter powder (SP). The sinter powder (SP) comprises at least one semicrystalline polyamide, at least one nylon-6I/6T and at least one polyaryl ether. The present invention further relates to a shaped body obtainable by the process of the invention and to the use of a polyaryl ether in a sinter powder (SP) for broadening the sintering window (WSP) of the sinter powder (SP).
US12214547B2	Additive-manufacturing systems and methods An additive manufacturing system and method includes a powder bed, an additive manufacturing head that is configured to emit a first energy into the powder bed to form at least one layer of a component, a part exposing mechanism that is configured to operate so that the component is in a first position at a first time within the powder bed, and a second position at a second time in which a portion of the component is exposed outside of the powder bed, and a surface smoothing head that is configured to emit a second energy onto the portion of the component in the second position to smooth the portion of the component.
US12214544B2	In situ chemical modification during additive manufacturing Additive manufacturing methods and systems are disclosed for chemical modification of a build material through at least 300 nm of the depth of each deposited layer. The depth of penetration of chemical modification is brought about through formation parameters including increased pressure, decreased humidity, formation temperatures, etc. Formed build product properties are improved as compared to those formed by traditional bulk manufacturing methods as well as to those formed by previously known additive manufacturing methods.
US12214541B2	Drawability enhancement in polymer thin films A method includes applying a stress to a polymer thin film to stretch the polymer thin film along a first in-plane direction, and subsequently applying a stress to the polymer thin film to stretch the polymer thin film along a second in-plane direction orthogonal to the first in-plane direction to form an ultra-high modulus polymer thin film. Calendaring or hot pressing of the ultra-high modulus polymer thin film may improve its optical and/or thermal properties.
US12214537B2	Extruder for manufacturing strand An extruder according to an embodiment includes: a screw configured to rotate around a rotation axis extending in one direction; a cylindrical cylinder extending in the one direction, the cylinder being configured to house the screw; a drive unit disposed at one end of the cylinder, the drive unit being configured to rotate the screw; a die disposed at the other end of the cylinder, the die being configured to discharge a raw material kneaded by the rotation of the screw a as a strand; an adjustment unit disposed between the cylinder and the die, the adjustment unit being configured to adjust a flow-velocity distribution of the raw material flowing into the die; and a detection unit configured to detect a discharge amount of the strand discharged from the die.
US12214532B2	Electronic device including housing and method for manufacturing the housing An electronic device is provided. The electronic device includes a housing; and a coating layer formed on at least a portion of a surface of the housing, wherein the coating layer comprises a paint, the paint including a one-component acrylate-based paint having a property of being cured by an ultraviolet (UV) light, or a one-component or two-component paint containing acryl and urethane and having a property of being cured by heat, wherein the coating layer has a pattern structure including an uneven pattern through laser processing on a portion of a coating film formed by applying the paint, and wherein two or more regions having different glossiness may exist on the surface of the housing by the pattern structure of the coating layer.
US12214525B2	Worktable assembly for tile cutter A worktable assembly for tile cutter includes a first table having a first surface and a slot recessed on the first surface and extending along a processing axis, and a second table installed in the first table and including a main body and an insertion member protruding from the main body along the processing axis and extending into the slot and having an insertion surface flush with the first surface. The second table can move relative to the first table along the processing axis, so that the main body is close to or far from the first table. The present invention provides better support through the cooperation of the slot and the insertion member and helps prevent the tile from breaking during processing.
US12214521B2	Method and system for layered wood product production A method and system for production of layered wood products employs local and independently operating robotic panel assembly cells including one or more veneer handling robots, one or more core handling robots, and one or more glue application robots to produce stacks of layered wood product panels locally near the pressing stations. Consequently, the stacks of layered wood product panels are independently built at, or near, the location of the pressing stations. This eliminates the need for traditional panel conveyors, traditional layered wood product panel assembly layup lines, and stack press delivery lines. This, in turn, eliminates thousands of moving parts and dozens of people from the layered wood product production process.
US12214520B2	Feed roll assembly, and mount and flute element therefor An elongate mount couples an insert to a feed roll via a proximal edge thereof. The proximal edge of the elongate mount faces both outwards in part and forwards in part. The elongate mount has a recessed region that is twisted in part. The insert is shaped to be received at least in part within and matingly engage with the elongate mount via the recessed region. The elongate mount is shaped to enclose the proximal edge, spaced-apart ends and backing fact of the insert.
US12214519B2	Saw apparatus with hydraulic tensioning A saw apparatus includes a guide bar, a chain driver, and an endless cutting chain trained about the guide bar and the chain driver. A hydraulic chain tensioning apparatus has a hydraulic actuator configured to be driven by a hydraulic power source to act against the guide bar to maintain tension in the cutting chain. A tension release valve is provided between the hydraulic power source and the hydraulic actuator. The tension release valve has a check valve, and a manual override press-button configured to maintain the check valve in an open condition while depressed. The tension release valve has a spring detent configured to maintain the manual override press-button in a depressed condition until selectively released.
US12214515B2	Razor cartridge A shaving razor system includes a razor handle that docks with a razor cartridge. The handle is configured to dock with the razor cartridge using a single hook configured to mate with a cartridge tab. A central pushrod is mounted with a spring into the handle and is configured to exert a pushing force on the mounted cartridge. To eject the cartridge, the single hook may be pushed to pivot to the side of the cartridge tab, and thereby release the razor cartridge by ejecting it with the spring loaded pushrod.
US12214514B2	Utility knife A utility knife including a handle, a blade, a first blade holder, and a spare blade holder. The spare blade holder is pivotal with respect to the handle between an open position where the recess is exposed to allow a spare blade to be removed from the spare blade holder and a closed position where the recess is within a slot of the handle to inhibit removal of the spare blade from the spare blade holder. The spare blade holder further including a cam surface and the cam surface of the spare blade holder engages a cam surface of the handle when the spare blade holder is in the closed position to urge the spare blade holder in a direction from a first longitudinal side of the handle toward a second longitudinal side of the handle to allow the first blade holder to pivot between extended and folded positions.
US12214512B2	Coordinating multiple robots to meet workflow and avoid conflict A robotic singulation system is disclosed. In various embodiments, sensor data including image data associated with a workspace is received. The sensor data is used to generate a three dimensional view of at least a portion of the workspace, the three dimensional view including boundaries of a plurality of items present in the workspace. A grasp strategy is determined for each of at least a subset of items, and for each grasp strategy a corresponding probability of grasp success is computed. The grasp strategies and corresponding probabilities of grasp success are used to determine and implement a plan to autonomously operate a robotic structure to pick one or more items from the workplace and place each item singly in a corresponding location in a singulation conveyance structure.
US12214509B2	Robot system to perform coordinated body work A system includes a first robotic arm and a second robotic arm, each coupled to a support structure configured to support an object. The first robotic arm includes a first end effector having a first shape, and the second robotic arm is separate from the first robotic arm and includes a second end effector having a second shape that mirrors the first shape when observed from a common perspective. The first end effector and/or the second end effector is asymmetric about at least one two-dimensional plane of that is perpendicular to an end effector plane of the at least one of the first end effector or the second end effector. At least one processor is operatively coupled to the first robotic arm and the second robotic arm, and configured to perform coordinated body work on the object using the first robotic arm and the second robotic arm.
US12214506B2	Method and system for robotic assembly A method for robotic assembly includes: receiving product data including product structure data and/or product geometry data of a product with a base component and at least one assembly part to be assembled; analyzing the product data to determine robot functions relating to functions of a robot for assembly of the product as determined robot functions; generating a robot program including assembly instructions dependent on the determined robot functions and the product data; and executing the generated robot program so as to identify and/or localize the at least one assembly part and assemble the product.
US12214498B2	Robot joint torque control system and load compensation method therefor A robot joint torque control system and a load compensation method therefor are provided, which relate to the technical field of robot joint motion control. A mathematical model of the robot joint torque control system is established first. Equivalent transformation is performed on a system functional block diagram thereof, and then it can be seen that load parameters have a great influence on joint torque output. A load compensation controller is designed to effectively eliminate the influence of the load parameters on an output torque of the joint. The system is equivalent to an inertial element on the basis of the compensation, and then a PD controller parameter is adjusted to increase an open-loop gain of the system, so as to increase a system bandwidth and increase a response speed of the joint torque control system, thereby improving performance of the joint torque control system.
US12214496B2	Learning software assisted automated manufacture Systems and methods for automated manufacture are provided. Nominal data measurements are obtained for an article. An identification scan is performed of parts within the work area by a machine vision system. An initial scan of the parts within or adjacent to the work area identified as being needed to form said article is performed by the machine vision system to identify target points. The target points are compared at a controller with the nominal data measurements. Automated material handling machines are commanded to grasp and move the parts within said work area to form the article.
US12214495B2	Method for learning robot task and robot system using the same The present invention relates to methods for learning a robot task and robots systems using the same. A robot system may include a robot configured to perform a task, and detect force information related to the task, a haptic controller configured to be manipulatable for teaching the robot, the haptic controller configured to output a haptic feedback based on the force information while teaching of the task to the robot is performed, a sensor configured to sense first information related to a task environment of the robot and second information related to a driving state of the robot, while the teaching is performed by the haptic controller for outputting the haptic feedback, and a computer configured to learn a motion of the robot related to the task, by using the first information and the second information, such that the robot autonomously performs the task.
US12214485B2	Robot for bio-surveillance and bio-surveillance system A mobile robot may include one or more driven wheels, one or more sensors, and a sample collector. The sample collector may include a collection medium holder, a plurality of collection mediums disposed within the collection medium holder, and a collection medium applicator configured to releasably couple to a respective collection medium disposed within the collection medium holder.
US12214482B2	Dry filtration system A mobile vehicle mounted dry filtration system to support a grinder system used for removal of markings, creating rumble strips, or the like. Blowers create a vacuum for drawing debris and dust from the grinder system into a debris bin. Large debris is removed from the vacuum draw and remains in the bin for later disposal. Small particles and dust are drawn into parallel positioned filter cyclones that have a cyclonic separation followed by flexible and inexpensive bag filters. The flexible filters are cleaned using vibrating diaphragms mounted on the top of the filter cyclones subject to a reverse air flow by the blowers using slide valves. A polishing tank containing water receives the exhaust from the filter cyclones for removal of airborne particles and sound suppression.
US12214479B2	Power head and outdoor power equipment using the same The disclosure provides a power head and an outdoor power equipment using the same. The power head includes a housing assembly, a motor assembly and a battery pack assembly. The housing assembly includes a first housing and a second housing. The first housing and the second housing defines a housing space. The motor assembly is arranged in the housing space. The motor assembly includes a motor. One end of an output shaft of the motor extends to outside of the housing assembly. The battery pack assembly is arranged inside the housing space. The battery pack assembly supplies power for the motor assembly.
US12214475B2	Retainer installation tool A retainer installation tool can facilitate installation of a retainer onto a vehicle body structure. In some arrangements, the retainer can be for a vehicle sonar sensor, and the vehicle body structure can be a bumper. The retainer installation tool can help to ensure proper placement of retainer, sufficient adhesion time, and/or placement of an adhesive. The retainer installation tool can include an outer casing. The retainer installation tool can include a central shaft extending partially within the outer casing. The retainer installation tool can include a handle operatively connected to cause rotation of the central shaft. The retainer installation tool can be configured to retainably engage a retainer. The retainer installation tool can be configured to selectively disengage the retainer when the central shaft is rotated.
US12214473B2	Impact screwing/unscrewing device with idling control An impact screwing/unscrewing device includes: an electric motor having a rotor; a controller for controlling the motor, which can transmit an instruction to the motor; and an impact mechanism. The impact mechanism includes: at least one anvil mounted to rotate about the axis of rotation of the rotor; at least one hammer capable of being rotated by the motor about the axis, the hammer being movable between at least: a non-engaged position in which it is not capable of colliding with the at least one anvil when the hammer is rotated by the motor, and an engaged position in which it is capable of colliding with the at least one anvil when the hammer is rotated by the motor. A variation of the instruction supplied to the motor by the controller triggers passage of the at least one hammer from one of the positions thereof to the other.
US12214468B2	Temperature control of chemical mechanical polishing A chemical mechanical polishing system includes a support to hold a polishing pad, a carrier head to hold a substrate against the polishing pad during a polishing process, an in-situ monitoring system configured to generate a signal indicative of an amount of material on the substrate, a temperature control system to control a temperature of the polishing process, and a controller coupled to the in-situ monitoring system and the temperature control system. The controller is configured to cause the temperature control system to vary the temperature of the polishing process in response to the signal.
US12214467B2	Skate blade sharpening system A skate blade grinding system used to sharpen and profile the blades of ice skates. The skate blade grinding system can include a housing that includes an elongated slot for receiving the blade of an ice skate for sharpening, and clamp jaws for retaining the skate. The skate blade grinding system can automatically operate a grinding wheel and move the rotating grinding wheel back and forth along the lower face of the skate blade to grind the skate blade.
US12214461B2	Automated container cutting system and method An automated container cutting system includes a cutting tool configured to cut a container and a force feedback sensor operatively connected to the cutting tool. The force feedback sensor is configured to measure resistive force exerted on the cutting tool. The automated container cutting system includes a processor communicatively coupled to the force feedback sensor. The processor is configured to receive resistive force data from the force feedback sensor and determine whether the cutting tool has penetrated through the wall of the container using the received resistive force data.
US12214457B2	Fastening tool A fastening tool includes: a cylindrical rotation guide member extending in one direction and rotatably supported; a holding member having an opening in which a driver bit is detachably inserted, and configured to move in an axis direction along the extension direction of the rotation guide member inside the rotation guide member and to rotate together with the rotation guide member; and a moving member configured to move the holding member in a front and rear direction along the rotation guide member; a rotation member; and a transmission member connected to the moving member and having flexibility to be wound along an outer periphery of the rotation member. The rotation member is rotated by the motor, so that the moving member is moved with the transmission member in one direction in which a screw engaged with the driver bit is pressed against a fastening target.
US12214453B2	Method and carrier gas nozzle for supplying a fluid to a welding area of a workpiece In a method and a carrier gas nozzle for allowing at least one fluid to flow over a welding area of a workpiece along a welding path during a welding process, the at least one fluid is flowed onto the welding area via at least one inlet and channels having openings. The openings of the channels are divided into at least two sectors, and at least one flow parameter, if need be also a property of the at least one fluid of each sector, is individually controlled, wherein at least one flow parameter of at least one fluid of at least one sector is controlled depending on the geometry of the welding path and/or depending on the geometry of the workpiece.
US12214452B2	Welding power source, welding system, welding power source control method, and program A welding power source is configured to supply a welding current to a wire as a consumable electrode. The welding power source includes a controller configured to change the welding current based on a position of a distal end of the wire a distance from which to a surface of a base metal varies periodically, in a case where the distal end of the wire is fed toward the base metal with periodical switching between a forward feeding period and a reverse feeding period.
US12214451B2	System for controlling welding parameter of a welding system Embodiments of a the present disclosure include a remote control system for a welding system having a control device and control circuitry configured to select a first operating parameter adjustment for a first operating parameter of the welding system based on a first actuation of the control device, wherein the first operating parameter adjustment comprises an adjustment to a rate of change of the first operating parameter.
US12214449B2	Mobile hardbanding unit A mobile hardbanding system that uses PTA welding to perform hardbanding on drill string sections at the well site. The inventive system allows alternate use of PTA and MIG welding. Both a PTA torch and a MIG torch are provided. Changing from one type of welding to the other is simplified by including separate electrical, gas, and cooling conduits for each torch. The torch not in use is parked in the welding compartment near the weld box. The powder hopper for the PTA welding assembly may be mounted on a swivel arm so that it can be moved out of the way when the MIG torch is in use.
US12214445B2	Inclined structure and method of manufacturing same A method of manufacturing an inclined structure extending in an oblique direction from a surface of a base metal includes: forming a base portion by stacking a plurality of build-up layers on the surface of the base metal, each of the plurality of build-up layers being formed by a plurality of beads, the base portion including a reference surface inclined at an opposite side of the oblique direction across a perpendicular line of the surface of the base metal; and forming a projecting portion by stacking a plurality of build-up layers on the reference surface of the base portion, each of the plurality of build-up layers being formed by a plurality of beads, the projecting portion extending in the oblique direction from the base portion.
US12214441B2	Method and system for determining the local position of at least one optical element in a machine for laser processing of a material, using low-coherence optical interferometry techniques A method for determining local position of an optical element associated with an optical path for transporting a laser beam in a working head of a machine for laser processing a material, includes generating a measurement beam of low coherence optical radiation traveling a measurement optical path, leading the measurement beam towards the optical element and the reflected or diffused measurement beam towards an optical interferometric sensor arrangement, generating a reference beam of low coherence optical radiation traveling a reference optical path and leading the reference beam towards the interferometric optical sensor arrangement, superimposing the measurement and reference beams on a common region of incidence, detecting a position of a pattern of interference fringes between the measurement and reference beams, and determining a difference in optical length between the measurement and reference optical paths as a function of the position of the interference pattern along an illumination axis, or of the frequency of the interference pattern in the frequency domain.
US12214440B1	Magnesium/titanium composite plate with large thickness ratios and gradient heterothermal rolling bonding method A magnesium/titanium composite plate with large thickness ratios and a gradient heterothermal rolling bonding method are provided by the present disclosure, relating to the technical field of rolling bonding plates. The method includes following steps: assembling blanks according to a sequence of titanium strip, transition layer foil and magnesium alloy plate to obtain a composite blank; carrying out induction heating treatment on one side of the titanium strip of the composite blank, then rolling, and carrying out heat treatment on a composite plate blank after rolling to obtain the magnesium/titanium composite plate with large thickness ratios; and a thickness ratio of the magnesium alloy plate to the titanium strip is greater than or equal to 20:1.
US12214439B2	Systems and methods for using coolant flow sensors to determine electrode loss in resistance welding A first electrode coolant path is configured to cool a first welding electrode by liquid coolant flowing from a supply path through the first electrode coolant path to a return path. A second electrode coolant path is configured to cool a second welding electrode by liquid coolant flowing from the supply path through the second electrode coolant path to the return path. Three or more valves are configured to stop or reduce liquid coolant flow through the first or second electrode coolant path and configured to stop or reduce liquid coolant backflow from the return path when the first or second welding electrode is at least partially detached. At least one valve is coupled in the first or second electrode coolant path. A drawback apparatus generates a suction force to draw liquid coolant away from a gap formed when the first or second welding electrode is at least partially detached.
US12214436B2	Laser soldering system and light shaping method thereof A laser soldering system includes a laser source module, a polarization adjusting assembly, a temperature sensor, and a controller. The laser source module is configured to emit a laser beam. The polarization adjusting assembly includes a plurality of polarization elements and at least one stepping motor. The polarization elements are configured to split the laser beam into a Gaussian beam and a ring-shaped beam. The Gaussian beam illuminates the first element, and the ring-shaped beam is illuminates the second element. The stepping motor is configured to adjust a size of the ring-shaped beam. The temperature sensor is configured to monitor temperatures of the first element and a temperature of the second element. The controller is electrically connected to the temperature sensor, the laser source module, and the polarization adjusting assembly.
US12214435B2	Bottoming tap and chaser and method of use A tap and chaser are provided each having a cylindrical tool receiver connected to a threading section by a shaft. The receiver and shaft are of diameters sufficiently small to enter the bore hole and distribute any off axis load onto a number of internal threads of the bore hole to dissipate loading. The threaded section includes a group of longitudinal flutes. Each of the lands of the threaded section includes a novel cutting face, tooth angle and rake angle to advantageously allow for threading deep blind holes.
US12214429B2	Hand-held power tool with a motor support for a drive motor A hand-held power tool, in particular a hammer drill, includes a tool holder and a housing which has two housing half-shells. The hand-held power tool further includes a drive unit for driving a tool holder arranged in the housing. The drive unit includes at least one drive motor arranged in a motor support and a gear unit arranged in a gear unit housing. The motor support is connected directly to at least one of the two housing half-shells via at least one non-positive connection and at least one positive-locking connection. A relevant fastening axis is assigned to the at least one non-positive connection and to the at least one positive-locking connection. The fastening axis is arranged at right angles to and at a distance from an axis of rotation assigned to the tool holder.
US12214428B2	Insert and cutting tool including same An insert includes a base of a cermet including hard particles and a binder phase. The base includes first and second surfaces, a cutting edge on at least a part of a ridge line of the first and second surfaces, a third surface opposite to the first surface, and a through hole from the first surface to the third surface. An inner wall constituting the through hole includes a binder-phase-riched layer having a higher content of the binder phase than an inside of the base, at least in a center part. A thickness of the binder-phase-ricked layer in the center part is larger than a thickness of the binder-phase-ricked layer in an end part of the inner wall. A cutting tool includes a holder which has a pocket located at an end, the insert located in the pocket, and a clamp inserted in the through hole of the insert.
US12214427B2	Insert and cutting tool An insert includes a base which includes a first surface, a second surface connecting to the first surface, and a cutting edge located on at least a part of a ridgeline of the first surface and the second surface. The first surface includes a plurality of grooves located at a position away from the ridgeline and extended at an angle of 20-90° relative to the ridgeline. The grooves are away from the ridgeline in a range of 40-700 μm. A width W of the grooves is 50-700 μm, and a depth D of the grooves is 20-700 μm. Spacing S between the grooves adjacent to each other is 50-700 μm. A cutting tool includes a holder, which has a length extending from a first end to a second end and includes a pocket located on a side of the first end, and the insert is located in the pocket.
US12214425B2	Method for manufacturing composite material, and composite material Methods for manufacturing a composite material and composite materials are provided. The method may include preparing a metal foam, preparing a mixture including the metal foam and a curable polymer, curing the curable polymer of the mixture to obtain a composite material, and performing a planarization treatment. The planarization treatment may be performed on the metal foam before preparing the mixture, on the mixture before curing the curable polymer, and/or on the composite material. The composite materials may include a metal foam and a polymer that is on a surface and/or in pores of the metal foam. The composite material may have a surface roughness of 2 μm or less and/or may have a thermal resistance of 0.5 Kin2/W or less at 20 psi.
US12214421B2	Three-dimensional (3D) printing In a three-dimensional (3D) printing method example, a metallic build material is applied. A binder fluid is selectively applied on at least a portion of the metallic build material. The binder fluid includes a liquid vehicle and polymer particles dispersed in the liquid vehicle. The application of the metallic build material and the selective application of the binder fluid are repeated to create a patterned green part. The patterned green part is heated to at about a melting point of the polymer particles to activate the binder fluid and create a cured green part. The cured green part is heated to a thermal decomposition temperature of the polymer particles to create an at least substantially polymer-free gray part. The at least substantially polymer-free gray part is heated to a sintering temperature to form a metallic part.
US12214420B2	Spheroidal titanium metallic powders with custom microstructures Methodologies, systems, and devices are provided for producing metal spheroidal powder products. By utilizing a microwave plasma, control over spheriodization and resulting microstructure can be tailored to meet desired demands.
US12214419B2	Method for operating a system of the iron and steel industry A method for operating a system of the iron and steel industry for producing a metal product with participation of a severing or forming device. The actual value of an indicator be calculated over a length section of the metal product for the metal product to be produced. The indicator represents the resistance of the metal product to severing or forming processes. The calculated actual value pIst for the indicator p is then compared to a predefined threshold value. The severing or forming also only actually takes place when the actual value of the indicator of the metal product is less than the threshold value. If a comparison should show that the actual value of the indicator is greater than the threshold value, before the severing or forming of the metal product, a local processing of the metal product is performed in the corresponding length section.
US12214418B2	Device for improving quality of aluminum alloy horizontal continuous casting billet by applying ultrasonic treatment A device for improving quality of aluminum alloy horizontal continuous casting billet by applying ultrasonic treatment is provided, including an ultrasonic generator, an ultrasonic transducer, an amplitude transformer, a holding furnace, an ultrasonic probe and a traction device. The ultrasonic generator is electrically connected with the ultrasonic transducer; the ultrasonic transducer is threadedly connected with the ultrasonic probe through the amplitude transformer, and the ultrasonic probe is placed in the holding furnace; a communication opening is formed at a bottom of the holding furnace, and the traction device is installed at the communication opening; the holding furnace is further poured with metal liquid.
US12214416B2	Laser weldable sterling alloy A sterling silver chain and method of manufacturing a sterling silver chain comprising a plurality of chain links. Each of the chain links can comprise a sterling silver wire, the sterling silver wire comprising a first end and a second end. Each of the first end and the second end of each of the plurality of chain links can be joined together through a weld. Each of the plurality of chain links can comprise at least 92.5% by weight silver and at least 6.5% by weight tin.
US12214415B2	Dynamic load measurement method for rotary forging device, dynamic load measuring device, method for calibrating rotary forging device, method for manufacturing hub unit bearing, and method for manufacturing vehicle A measuring pressing die (43) is supported by a spherical concave seat (12). A measuring shaft member (45) is disposed coaxially with a reference axis (α) and is linearly guided in a direction of the reference axis (α) between the measuring pressing die (43) and a support table (16). After that, the load application apparatus measures an actual load in the direction of the reference axis (α) applied to the measuring shaft member (45) using a load cell (48) in a state in which the measuring pressing die (43) is pressed against the measuring shaft member (45) while the measuring pressing die (43) is rotated about the reference axis (α).
US12214414B2	Linear-actuated press machine having multiple motors and clutch system for multi-speed drive functionality A press machine comprises a moveable press ram, an actuator, a first motor system, a second motor system, and a belt system. The moveable press ram holds a tool that forms a part. The actuator linearly moves the moveable press ram by use of a male-female thread mechanism. The actuator includes an actuator sprocket coupled to the male-female thread mechanism. The first motor system produces a high-force linear movement condition to the press ram, and includes a clutch coupled to a first motor and a first motor sprocket coupled to the clutch. The second motor system produces a high-speed linear movement condition to the press ram. The belt system couples the actuator sprocket, the first motor sprocket, and the second motor sprocket. The clutch allows the first motor to partially or fully disengage from rotational movement of the first sprocket when the belt is being driven by the second motor.
US12214411B2	Fast change fold-a-way cross bow swing arm multiple die tubing bender A tubing bender device includes a frame, handle, ratchet mechanism, slide rod and a frame notch. The tubing bender may be easily disassembled and assembled into a forward or reverse configuration through the use of connectors, two brackets and a bending mandrel. Reversibility is also provided by a cross bow bar support releasably secured to either the slide rod or to a bracket. The cross bow bar support may also be inverted to position die heads in either an upward or downward direction. Repositionable die heads may also be rotated relative to the support into an operative configuration when bending smaller diameter tubing. The repositionable die heads are rotated relative to the support into a non-operative configuration when bending larger diameter tubing.
US12214408B2	Ram assembly with removable punch mounting assembly An assembly includes an elongated ram body and a punch mounting assembly. The ram body has a reduced length. The punch mounting assembly includes an elongated body having a complementary length. The punch mounting assembly is coupled to the ram body. The assembled punch mounting assembly and ram body have an operational length.
US12214404B2	Press brake for bending workpieces A press brake for bending workpieces includes: a fixed table beam with a lower tool holder, a displaceable press beam with an upper tool holder, wherein the press beam is formed so as to be displaceable relative to the table beam, and a graphic display for displaying information. In the displaceable press beam, a recess is formed, in which the graphic display is accommodated, wherein the graphic display has a display height and a display width.
US12214402B2	Electric pipe expander An electric pipe expander and intelligent control circuit for the electric pipe expander are provided. The electric pipe expander includes a pipe expander body and a mandrel sliding cavity disposed on the pipe expander body. A chuck body capable of clamping a pipe to be processed is disposed at an opening end of the mandrel sliding cavity. A mandrel is slidingly connected in the mandrel sliding cavity, an outer side end of the mandrel is provided with an obliquely disposed pipe expanding cone, an inner side end of the mandrel is provided with an elastic body accommodating cavity. Flat keys are disposed on the mandrel, and an elastic body is clamped and disposed between the flat keys and a bottom surface of the elastic body accommodating cavity.
US12214397B2	Vehicle body element dent system and method A vehicle body dent system may include a dent impactor, which may include a ram and an impactor head on one end of the ram. The ram may be adapted to accelerate the impactor head to forcefully make contact with a vehicle body element, thereby denting the vehicle body element. The impactor head may be replaceable on the ram. Different impactor heads of numerous shapes and sizes may be provided. The ram may be a pneumatic cylinder, as such the criteria of a dent may be the classification of the impactor head used, such as the diameter of the impactor head, and the air pressure provided to the cylinder which may comprise the ram. The vehicle body element may be supported by a body element support, which may include a rotating portion. The body element support may include a mounting element in the form of a body element table, or one or more standoffs, movably mounted to the body element support. The mounting element may be adapted to receive the vehicle body element and securely support the vehicle body element. The mounting element may be coupled to the rotating portion of the body element support so that the vehicle body element mounted to the body element support may be positioned substantially horizontal or substantially vertical that may represent the position of the vehicle body element as if it were on a vehicle where a technician can be trained to remove the dent.
US12214396B2	Seam forming apparatus for elbow duct A device for forming seam of elbow duct is provided, and the device for forming seam of elbow duct that molds a lockseam by bending a flange of one pair of adjacent unit members, of a plurality of unit members constituting the elbow duct, including a base that supports a lower portion of the one pair of unit members; an elevating part that moves the base up and down; an angle adjustment part that adjusts a supporting angle of the base; a fixing chuck that supports an inner circumferential surface of a connecting portion of the one pair of unit members; a rotating part that rotates the fixing chuck; and a forming part that bends the flange of the one pair of unit members in a state where the flange is in contact to each other, to form the seam.
US12214390B2	Portable gas monitor A portable monitor used to measure landfill gas and landfill well parameters. The portable monitor includes a control unit and a measuring unit that can communicate wirelessly with one another. The control unit and/or measuring unit can include a heating arrangement to increase the temperature of one or more components in the control unit and/or measuring unit in cold environments.
US12214389B2	Auto-indexing lance positioner apparatus and system A system and an apparatus for positioning a plurality of flexible cleaning lances through tubes penetrating a tube sheet of a heat exchanger tube sheet, includes a smart lance tractor drive, a controller, and a tumble box connected to the controller operable to generate and/or distribute electrical power to the AC induction sensor from an air pressure source, supply electrical power to the controller and distribute pneumatic power to pneumatic motors for positioning the tractor drive on the positioner frame. The smart tractor drive includes sensors for detection of mismatch between expected and actual lance positions, sense lance insertion distance and lance removal and provide automated drive reversal operation to remove blockages within tubes being cleaned.
US12214387B2	System and method for creating and performing an installation cleaning process for process installations Method and system for creating and implementing a cleaning-in-place installation cleaning process for a process installation, wherein an installation to be cleaned is represented as process modules that each include an item of self-description information with respect to the respective cleaning properties and that are each configured to transmit the self-description information, where the system has at least one auxiliary module that provides auxiliary services for the installation cleaning process, and a process planning unit that has an item of cleaning process information having cleaning steps needed at least for the installation cleaning process and model descriptions of cleaning efficiency for each cleaning step, and the process planning unit determines a cleaning schedule in a partially automated manner on a system-specific basis based on the cleaning process information supplemented with self-description information relating to the process modules and taking into account information relating to the at least one auxiliary module.
US12214383B2	Robotic system for performing pattern recognition-based inspection of pharmaceutical containers A robotic inspection platform comprises a robotic arm, an imager, and a controller. The controller causes the robotic arm to retrieve, using its end effector, a container, and to manipulate the container such that the container is sequentially placed in a plurality of orientations while in view of the imager. The controller also causes the imager to capture images, with each of the images being captured while the container is in a respective one of the orientations. The controller also determines one or more attributes of the container, and/or a sample within the container, by analyzing the images using a pattern recognition model and, based on the attribute(s), determines whether the container and/or sample satisfies one or more criteria. If the container and/or sample fails to satisfy the criteria, the controller causes the robotic arm to place the container in an area (e.g., bin) reserved for rejected containers and/or samples.
US12214377B2	Conformal coating process with thickness control A method for controlling a dispensing system is provided, including the steps of dispensing, by a dispensing device, a coating material onto a substrate according to a first dispensing operation, inspecting, by an inspection device integrated with the dispensing device, the coating material applied to the first substrate, and altering the first dispensing operation based on the inspecting so that the coating material is dispensed onto a subsequent substrate according to a second dispensing operation. An associated coating machine is also provided.
US12214370B2	Double tentacle pump system for a liquid sprayer A double tentacle pump system for a liquid sprayer includes first and second tentacle pumps positioned serially within a flow path that extends between a liquid container and the outlet of the sprayer. A motor is configured to actuate the first and second tentacle motors in response to a user directed trigger, thereby causing fluid to be moved from the container and expelled from the sprayer.
US12214365B2	Electrification apparatus for electric dust collection and air conditioner for vehicle including same An electrification apparatus is used for electric dust collection in an air conditioner for a vehicle. The electrification apparatus includes a frame, a conductive microfiber, and a conductive plate. The frame includes a main body frame in which the conductive plate is installed and an installation frame that defines a fixing groove in which the conductive microfiber is installed. The electrification apparatus further includes a rubber coupled with the conductive microfiber and inserted into the fixing groove.
US12214364B2	Filter media for active field polarized media air cleaner Filter media for an active field polarized media air cleaner includes two layers of dielectric material with a higher resistance air permeable screen sandwiched between the lower resistivity electric layers. The filter media may further include a mixed fiber filter layer having fibers from different sides of the triboelectric scale. The filter media may further include a layer of relatively higher density dielectric material followed by a layer of relatively lower density dielectric material.
US12214362B2	Process of recycling a bituminous waste product such as a waste bituminous membrane product A process of recycling a bituminous product or a bituminous membrane product contacting reinforcement layers. Collecting the waste bituminous products and sorting it in a series of waste bituminous product batches. At least one grinding step of each batch in each series forms a fine ground batch. The fine ground batch is introduced into a recycling unit wherein the fine ground batch is heated and melted and collected as a melted product. The melted product is fed into a mixing tank having a predetermined volume containing fresh carrier.
US12214359B1	Colloid mill The shear gap between a rotor and a stator in a colloid mill is adjusted by translating the stator with respect to the rotor, preferably by moving the stator along a helical path about the rotor, thereby moving the stator's surface closer to or further from the rotor's surface (and altering the shear gap therebetween). Helical slots are provided in the casing about the stator, with members extending from the stator through the slots, whereby the members can be grasped and rotated about the casing to move the stator. Channels allowing circulation of buffer fluid are provided about the stator and rotor to deter ingress of the fluid being processed into junctures between components of the colloid mill.
US12214351B2	Developer solution vial The invention provides a developer solution vial and methods of its use to diagnose diseases using a sampling and/or assay device, for example, for use with a lateral flow assay (LFA) device. The developer solution vial may include any container that is capable of holding developer solution. The developer solution vial is keyed to the sampling and/or assay device. The developer solution vial minimizes the amount of developer solution required for accurate fluid flow assay testing.
US12214350B2	Microfluidic devices A microfluidic device is configured to sample, meter and collect a metered volume of body fluid for analysis by means of capillary transport. The device comprises: an inlet section, for receiving the body fluid sample, the inlet section comprising an inlet port; a metering section configured to receive body fluid from the inlet section and comprising a metering channel, wherein the metering section is arranged to separate a metered volume of body fluid filled in the metering channel; and an outlet section comprising a cavity between an outlet part of the metering channel and an outlet orifice of the device, a hydrophilic porous bridge element conformable to a shape of the cavity and inserted in the cavity to substantially fill the cavity and the outlet orifice, and a capillary means attached to the outlet section in contact with the hydrophilic porous bridge element.
US12214347B2	Nanopore/nanowell electrode enabled exonuclease sequencing Devices and methods are provided for identifying individual monomeric units in sequential order as they are released or cleaved from a polymer strand via an enzyme, which acts on the polymer, and the monomeric units translocate through a transmembrane channel. Methods are also provided for identifying molecules as they translocate through a transmembrane channel.
US12214346B2	Dermal patch with a diagnostic test strip A system for analyzing a physiological sample includes a cartridge configured to attach to the skin of a subject. The cartridge includes: a processing fluid pack that is configured to release a processing fluid stored therein, a diagnostic test strip, and a vacuum pin. The system also includes a lancet with a needle. The lancet is configured to deploy the needle upon engagement with the cartridge to draw a physiological sample from the subject. The vacuum pin is configured to create a vacuum within the cartridge to draw the released processing fluid and the drawn physiological sample to the diagnostic test strip.
US12214345B2	Multi-stage oral-fluid testing device with cap containing plunger for oral-fluid release from collection sponge In an embodiment, the claimed invention includes an oral-fluid collection and testing device that. is simple to operate. The device includes a body assembly and a cap assembly that are easy to handle by a user. A collection sponge projects from an end of the body assembly for absorbing the oral fluid of a donor, A cap assembly is easily aligned with the body assembly by way of visual alignment indicators on both the body and the cap. Once the cap is aligned with the body, a user simply pushes the cap onto the ‘body, which causes a first stage fluid, flow. More specifically, a buffer fluid is released from the cap and mixes with the oral fluid collected on the sponge—After waiting a short time* the cap is rotated, then pushed again, causing a second-stage fluid flow in which the sponge is compressed such that the buffer fluid/oral fluid exits the sponge and flows toward a. pair of test strips. A user can then easily view the test results by observing a visual indication, such as a color change of the test strips through a viewing window.
US12214342B2	Systems and methods for segregating into dual waste streams oxidizable catalyst material from inert support media A method for disposing of a mixture of oxidizable catalyst material and inert support media. The method comprises introducing inert gas into an enclosure. The enclosure contains a plurality of stacked screens, the stacked screens have openings that decrease in size from a top of the stack to a bottom of the stack. The method also comprises introducing the mixture to an uppermost one of the plurality of stacked screens; moving the plurality of stacked screens to cause the oxidizable catalyst material to separate from and migrate to a location beneath the inert support media; conveying the separated inert support media to a location outside the enclosure for disposal as non-hazardous waste; and conveying the separated oxidizable catalyst material to a location outside the enclosure for at least one of reclamation, or thermal destruction.
US12214339B2	Nanocage-confined catalyst, preparation process and use thereof A nanocage-confined catalyst has the formula: NC-m[M(Salen1)X]-n[M′(Salen2)]. NC is a material having a nanocage structure, and M(Salen1)X and M′ (Salen2) are active centers, respectively; each occurrence of M is independently selected from the group consisting of Co ion, Fe ion, Ga ion, Al ion, Cr ion, and a mixture thereof. Each occurrence of M′ is independently selected from Cu ion, Ni ion and a mixture thereof, m is 0 to 100; n is 0 to 100, with the proviso that at least one of m and n is not 0; each occurrence of Salen1 and Salen2 is independently a derivative of Shiff bases; X is an axial anion selected from the group consisting of substituted or unsubstituted acetate, substituted or unsubstituted benzene sulfonate, substituted or unsubstituted benzoate, F—, Cl—, Br—, I—, SbF6-, PF6-, BF4-, and a mixture thereof.
US12214333B2	Mixed oxide based on cerium and zirconium A mixed oxide, a catalytic composition, a catalytic wall-flow monolith, the use of the mixed oxide and the process of the preparation of the mixed oxide. The mixed oxide comprises zirconium, cerium, lanthanum and optionally at least one rare earth element other than cerium and other than lanthanum. The catalytic composition and the wall-flow monolith comprise the particles of the mixed oxide. The use of the mixed oxide is in the preparation of a coating on a filter. The process of preparation of the mixed oxide consists jet milling. The mixed oxide is a compromise between a calibrated size and a low viscosity when in the form of an aqueous slurry while retaining a high specific surface area and a high pore volume.
US12214331B2	Processes for preparing functional particles for use in electrochemical cells and electrochemical cells including said functional particles Methods of making functional particles, such as functional lithium ion-exchanged zeolite particles and functional electrode particles for electrochemical cells are provided as well as electrochemical cells including such particles. A method includes combining a solution including (NH4)3PO4 with lithium ion-exchanged zeolite particles to form a first mixture. The method further includes adding a polymeric binder and a lithium salt to the first mixture to form a first slurry including the functional lithium ion-exchanged zeolite particles comprising Li3PO4.
US12214328B2	Method for disruption of solid materials in a fluid medium A method for disrupting solid materials suspended in a fluid medium includes introducing a fluid comprising solid materials dispersed in a fluid medium into a fluid duct, flowing the fluid through an annular space between a cylindrical wall of the fluid duct and an outer surface of a cylindrical acoustic projector that is concentric with the cylindrical wall, the acoustic projector comprising a plurality of hammer elements spaced apart from one another by a first plurality of slots in the acoustic projector, supplying electrical energy to a transducer coupled to the acoustic projector to cause the acoustic projector to vibrate, thereby causing cavitations in the fluid, and flowing the fluid through an outlet of the disruptor after the fluid has been exposed to the cavitations. The cavitations can disrupt solid materials such as pulp, flowers, stems and seeds to release juice or oils from the materials.
US12214324B2	Liquid mixing system with vertically adjustable mixing element and method of use A liquid mixing system includes a support housing at least partially bounding a compartment. A mount is secured to the support housing. A drive motor assembly is configured to engage a drive shaft for moving the drive shaft within the compartment of the support housing. A four bar linkage system extends between the mount and the drive motor assembly, the four bar linkage system being movable between a first position wherein the drive motor assembly is disposed at a first elevation and a second position wherein the drive motor assembly is disposed at a second elevation that is different from the first elevation.
US12214321B2	Devices and systems for preparing a chemical solution A device is provided for preparing a chemical solution. The device comprises a dissolving bowl having an open top portion for receiving a solid chemical material and a closed bottom portion. A grid member is disposed between the top and bottom portions for supporting the chemical material on a top surface thereof defining an array of grid openings and a flow opening distinct therefrom. A nozzle is positioned proximate the bottom portion and directs flow of an aqueous fluid to contact and dissolve at least some of the chemical material and create a chemical solution thereof Δn insert disposed proximate the grid member impedes flow of the aqueous fluid through one or more of the grid openings to increase fluid turbulence within the dissolving bowl and/or redirects the fluid flowing from the flow opening to flow in one or more directions over the grid member.
US12214320B2	Separator membrane having hierarchical structure comprising mesopores, production method therefor and xylene separation method using same The present invention relates to a separator membrane having a hierarchical structure, a production method therefor and a xylene separation method using same, and to: a separator membrane having a hierarchical structure comprising mesopores, the separator membrane having mesopores introduced inside a microporous zeolite separator membrane, thereby being thin, having less defects and exhibiting high xylene permeation and separation performance; a production method therefor; and a xylene separation method using same.
US12214309B2	Passive dust filter for an inspection hatch The invention is directed to a passive dust filtering system for an inspection hatch of steel bulk storage vessel. The system includes a filter containment unit and an adaptor section for securing the unit to the storage vessel. The adaptor section includes a mounting flange having one or more magnetic switches to engage the storage vessel. A purge control system is used to periodically pulse air into filter elements in the filter containment unit to blow dust from the outside of the filter elements back into the vessel.
US12214308B2	Continuously regenerable scrubber Regeneration of a fluid medium can be accomplished using a continuously regenerable scrubber, which, in its various embodiments, combines valve functions and sorbent material, such as amine beds, into one component, dramatically reducing size and mass of scrubber. Sorbent material beds rotate continuously past breathing gas vent loop ports for scrubbing CO2/H2O and then past vacuum ports for regenerating the sorbent material. Typically, a first fluid output is connected to a lower header fluid output and a second, sweeping fluid source connected to a lower header fluid input. A motor spins the substantially circular bed assembly at a predetermined speed which allows adsorption or absorption as well as desorption of materials flowing through the sorbent material.
US12214307B2	Air cleaner assemblies and methods of use An air cleaner assembly is disclosed. In one aspect, the air cleaner assembly includes a housing defining an inlet and an outlet, and including an access opening between the inlet and outlet. The air cleaner also includes a filter cartridge received within the housing and covering the access opening. The air cleaner also includes a lock mechanism. The lock mechanism is movable between an unlocked position in which the filter cartridge can be installed and removed from the housing and a locked position in which the filter cartridge is secured within the housing. The filter cartridge and lock mechanism include interacting features allowing the lock mechanism to be moved from the unlocked position to the locked position only when the filter cartridge is installed within the housing.
US12214306B2	Filter device An outflow portion that causes a space inside a filter element to communicate with a space outside a filter case includes an upper surface and a bottom surface that are provided so as to be separated from each other. The back pressure valve includes the valve body having the substantially plate-like shape and the elastic member provided between the bottom surface and the valve body. The valve body is movable between a closed position in which the valve body is in contact with the upper surface, and an open position in which the valve body is not in contact with the upper surface. A recessed portion is provided in a surface, of the valve body, that comes into contact with the upper surface, and an outflow port is formed in a side surface or the upper surface of the outflow portion.
US12214305B2	Device and method for filtering a fluid circulating in a plumbing and heating system The present invention relates to a device (1) for filtering a fluid circulating in a plumbing and heating system, comprising a body (2) defining therewithin a filtration chamber (3) that is destined to have a fluid to be subjected to filtration pass through it. The body is provided with a first inlet/outlet opening (10), a second inlet/outlet opening (20) and a third inlet/outlet opening (30): each of which sets the filtration chamber (3) in communication with the outside of the device and can be associated with a line of the system to receive therefrom, or send thereto a fluid entering or exiting said body of the device. The device operates a passage of fluid through the filtration chamber (3), in a selective manner according to a plurality of operative configurations, from an opening between said first (10), second (20) and third inlet/outlet opening (30) to a further opening between said first, second and third inlet/outlet opening. The device further comprises filtering members (40) housed inside the filtration chamber and interposed between the inlet/outlet openings to perform filtering of the fluid passing through the filtration chamber; the filtering members comprise a mechanical filter (41) arranged in the filtration chamber and structured so as to divide the filtration chamber into a first sub-chamber (A), a second sub-chamber (B) and a third sub-chamber (C), in which the first sub-chamber is in fluid communication, without passing through the mechanical filter, with the first inlet/outlet opening, the second sub-chamber is in fluid communication, without passing through the mechanical filter, with the second inlet/outlet opening, and the third sub-chamber is in fluid communication, without passing through the mechanical filter, with the third inlet/outlet opening.
US12214304B2	Separating hydrocarbons with dihydrolevoglucosenone or a derivative of dihydrolevoglucosenone as a solvent The present invention provides a process for separating unsaturated hydrocarbons from a mixture of saturated and unsaturated hydrocarbons, which process comprises the steps of (a) contacting the mixture with a solvent; (b) allowing to form two phases in equilibrium, a first phase comprising solvent and unsaturated hydrocarbons and a second phase comprising the remainder of the mixture; (c) removing the phases separately; and (d) removing from at least one of the phases the hydrocarbons to obtain at least one product stream and regenerated solvent for use in step (a), wherein the solvent comprises dihydrolevoglucosenone or a derivative of dihydrolevoglucosenone.
US12214302B2	Oil filter cartridge A filter cartridge configured to be removably inserted into a space of a filter housing that has a housing socket and a housing cover with a sealing surface facing inwards. The filter cartridge has a filter element forming a fluid channel with a longitudinal axis, a front end, and a rear end, as well as a connector element with a peripheral surface that provides for an increased filter area, if the peripheral surface includes a first ring surface and a second ring surface (which are plain bearing surfaces) and if a gasket is movably supported in a first axial position on the first ring surface, thereby enabling a translation of the gasket in a first direction to a second axial position onto the second ring surface.
US12214298B2	Systems and method for detection of analytes in high volumetric flow applications The present disclosure relates to the detection of analytes in high volumetric flow applications. Particular embodiments relate to the use of fluorescence polarization/anisotropy based for detection of analytes in a flow cell. In one testing format, an analyte of interest is probed with reagents containing fluorescent labeled recognition elements. When present in a sample or portion of a sample, the labeled analyte produces a shift in fluorescence polarization/anisotropy/intensity/lifetime as the output signal following the binding of the recognition elements to the analytes.
US12214297B2	Regulated method for separating a mixture The invention relates to a method for separating a mixture in an installation comprising a first system comprising a plurality of chromatography columns, a second system downstream of the first system and a tank fed by an outlet line of the first system and feeding the second system with a continuous stream, the method successively comprising, in a cyclical manner, in a given part of the first system, steps of collecting a raffinate, injecting the mixture to be separated, collecting an extract and injecting a mobile phase; wherein the method further comprises the measurement of the purity and/or yield of at least one collected fraction, comprising: the determination of the concentration of at least two species of the mixture to be separated in the fraction collected in the tank; and the determination of the purity and/or yield of at least one species of the fraction collected in the tank.
US12214295B2	Solvent-extract filter apparatuses and methods A filter apparatus includes an elongated housing with a filter input port to the housing and a filter output port to the housing. A mixture flow path is defined within the housing and extends from the filter input port to the filter output port such that the filter input port is in fluid communication with the output port through the mixture flow path. Two or more filter medium receiving volumes are defined within the housing along the mixture flow path, each filter medium receiving volume configured to receive a filter medium and contain the filter medium in the respective filter medium receiving volume. The filter medium receiving volumes are arranged within the housing such that a total length of the filter medium receiving volumes along a housing longitudinal axis is longer than the length of the housing along the housing longitudinal axis defined by the housing.
US12214293B2	Transformable toy Provided is a transformable toy including a vehicle body having a lower surface provided with wheels and an upper surface opposite to the lower surface, and a straight-running driving assembly disposed in the vehicle body. The vehicle body includes at least two sections, a rotation driving assembly is disposed between two adjacent sections of the vehicle body and configured to drive the at least two sections of the vehicle body to rotate relative to each other to transform the vehicle body; when the at least two sections of the vehicle body rotate relative to each other into a transformed state, the vehicle body is in a rollable shape; when the at least two sections of the vehicle body rotate relative to each other into an unfolded state, the vehicle body runs under the action of the straight-running driving assembly.
US12214292B2	Storage device with movable element In an aspect, a storage device is provided and includes a container including an exterior surface and an opening therethrough. The storage device further includes at least one movable facial feature element. The storage device further includes an actuator operatively connected to the at least one movable facial feature element for driving movement of the at least one movable facial feature element. The storage device further includes a closure structure extending along the opening, and a traveler that is movably mounted to the closure structure for movement between a first traveler position and a second traveler position to open or close the closure structure. A coupling arrangement connects the traveler to the actuator such that movement of the traveler drives movement of the actuator, which in turn drives movement of the at least one movable facial feature element.
US12214291B2	Container inflator system and a method for inflating a balloon A container inflator system (100) includes a suction chamber (102) arranged to expand the container within the suction chamber (102) while maintaining at least one opening for accessing the container; an inflation device (104) arranged to further inflate the container when the container is removed from the suction chamber (102); and a delivery valve (302) arranged to seal the container so as to maintain the expanded state of the container when it is removed from the suction chamber (102).
US12214290B2	Motion simulator A motion simulator includes a base plate, a motion platform, a first actuator, a base, a second actuator and a carrying platform. The motion platform is arranged on the base plate and movably connected to the base plate. The first actuator is arranged on the motion platform, movably connected to the motion platform. The base has a base body extending in a length direction and a base extension surface extending in a width direction. The first actuator is movably connected to the base extension surface. The second actuator is movably arranged on the base. The carrying platform is movably connected to the second actuator. Through a connection relationship between the base and the second actuator, the first actuator performs a left-right movement of the carrying platform relative to the motion platform and the second actuator performs the forward-backward movement of the carrying platform relative to the motion platform.
US12214287B2	Imaging video frames on documents Security-enhanced documents and methods of forming security-enhanced documents having indicia under a Scratch-Off Coating (SOC), and more particularly including digitally imaging video frames onto the display area and/or back of the documents. In certain embodiments, portions of digitally imaged video frames are also utilized as game play variable indicia.
US12214281B2	Operator interface for automated game content generation A game management system provides a generator interface that enables an operator to trigger automated generation by a content generator of a game event based on operator input values. These values include a particular predefined group or cluster of players for whom the game event is to be tailored or customized based on multidimensional parametric player model data. Additional parameters for which operator input mechanisms are provided by the generator interface include respective target values for a target metric (e.g., a difficulty level) for each of a plurality of game levels that are together to form a game event.
US12214280B2	Controlling a user interface A set of levels of a game is displayed and a user selection of one of the levels detected. It is determined that the user is partaking in a fragment collection event, the fragment collection event defining a set of collection conditions, and that one of the collection conditions is satisfied. Fragments are assigned to the user, the fragments having no utility within a game environment, wherein only one collection condition can be satisfied per level selection. A fragment count is stored, where assigning the one or more fragments to the user comprises incrementing the fragment count associated with the user by a predefined amount associated with the satisfied collection condition. When the fragment count is equal to or greater than a threshold fragment count, the fragment count is decreased by an amount equal to the threshold fragment count and a utility object assigned to the user.
US12214277B2	Method and device for generating video frames A method of generating video frames for a cloud-based video game includes obtaining, via a communications network, a plurality of frames of a video game rendered at a cloud device; obtaining a player input received at an input device, the input device being used to play the video game, the player input being received in response to the display of at least one of the obtained video frames; inputting at least one of the obtained video frames and the player input to a prediction model; and synthesizing, based on the output of the prediction model, a subsequent frame for output at a display, and outputting the synthesized video frame at the display.
US12214274B2	Avatar-incentive healthcare therapy An avatar-incentive healthcare therapy system has a physiological monitor for generating a physiological parameter indicative of physical health. An academic test for generating a test score is indicative of mental acuity. The avatar has outward characteristics and game play capabilities proportional to the physiological health and the mental acuity so as to incentivize improved physical health and academic performance.
US12214272B2	Method for generating position signals while using a virtual reality headset A method controls a piece of exercise equipment when a user of the exercise equipment is using a virtual reality headset. The method begins by receiving sensor inputs detecting a position of the user with respect to the exercise equipment. An operational zone of the exercise equipment is then determined. It is then identified when the user is moving toward a warning area within the operational zone of the exercise equipment. The method then sends signals to the virtual reality headset. Based on the signals, the virtual reality headset creates audible and visual outputs to instruct the user to move back fully into the operational zone of the exercise equipment.
US12214269B2	Compact ball launching system and associated methods This disclosure relates to a relatively compact smart ball launching system and associated methods for using the same. In various embodiments, the disclosed ball launching system may comprise a collapsible ball hopper that can store a larger number of balls while maintaining a relatively compact size. In certain embodiments, brushless motors may be used to improve power efficiency while allowing for accurate launch speeds and/or spins. In some embodiments, a pre-launch chamber may be included in a ball dispensing mechanism that may facilitate on-demand shots and/or power savings by shutting the ball launching system down when the ball hopper is empty. In further embodiments, the ball launching system may be controlled, at least in part, via a mobile device. In some implementations, the ball launching system may include and/or otherwise interface with a camera system to facilitate improved calibration and/or record user actions.
US12214267B2	Golf tee tool An apparatus and method for convenient and safe carriage of golf tees in a pocket or a mount point for a ball marker is disclosed. The golf tee tool includes an elongated channel dimensioned to receive a ground-penetrating tip and shaft of a golf tee. A fluted frustoconical opening at a proximal end of the golf tee tool is dimensioned to receive the cupped ball support of the golf tee. A magnet mounted at a distal end of the golf tee tool is configured to allow the golf tee tool to retrieve a ferrous ball marker from a putting green surface or the golfer's pocket. The golf tee tool may carry a single or multiple golf tees. The golf tee tool may provide for carriage of a divot repair tool and a ball marker. A clip assembly is also disclosed for coupling the golf tee tool to an article.
US12214265B1	Golf club face plate having correlated characteristic time measurement map A variable thickness face plate for a golf club head includes a peripheral edge having an upper peripheral edge and a lower peripheral edge, and a plurality of regions of constant thickness defined by an internal surface of the face plate. The plurality of regions of constant thickness include a first subset of regions of constant thickness being disposed along a first horizontally-extending path proximate the upper peripheral edge, the first horizontally-extending path being disposed radially inward from and parallel to the upper peripheral edge, and a second subset of regions of constant thickness being disposed along a second horizontally-extending path proximate the lower peripheral edge, the second horizontally-extending path being disposed radially inward from and parallel to the lower peripheral edge.
US12214263B1	Systems and methods for additive manufacturing of a golf club having an insert structure A golf club head includes a body and an insert. The body defines a top side, a toe side, and a heel side, and includes a sole extending between the toe side and the heel side at a location on the body opposite to the top side. The body defines an internal volume defined between a ball-striking face and an internal wall. The insert is arranged within the internal volume and is formed layer by layer via an additive manufacturing process. The insert includes a lattice structure arranged between a rear surface of the ball-striking face and the internal wall. The lattice structure is in engagement with the rear surface and formed integrally with the ball-striking face and the internal wall.
US12214262B2	Lens assembly structure of swimming goggles The present invention provides a lens assembly structure of swimming goggles. The lens assembly structure comprises two lenses, two retaining walls, two skirt portions, and two frame portions. Each of the lenses includes an eye side and a water side opposing to the eye side. The two retaining walls are provided on the eye sides of the lenses, respectively, and each of the retaining walls defines a visible area and a connection area. Each of the retaining walls has a configuration, and the corresponding skirt portion is disposed along the configuration. The connection area of the lens is affixed in the corresponding frame portion. The configuration of each of the retaining walls is a curve having a contour which is less complicated than a peripheral configuration of the lens.
US12214261B1	Buoyant devices The embodiments of the present disclosure provide a buoyant device including a body composed of a material with a specific gravity less than 0.3. The body is composed of a portion between a first distance and a second distance from an axis. The body includes a first portion, a second portion, and a third portion. Differences of the first portion and distance differences of the second portion are less than a distance difference of the third portion. The first portion includes a first difference group and a second difference group composed of a plurality of distance differences, and distance differences of the first difference group are greater than distance differences of the second difference group. The second portion is located away from the axis relative to the first portion.
US12214259B2	Systems and methods for the production, management, syndication and distribution of digital assets through a network in a micro-subscription-based platform Systems and methods are for production, management, syndication and distribution of digital assets through a network such as the Internet or wireless network. Digital media assets are distributed to consumers through a syndicated network of Outlets under control of a central platform. Distribution is format agnostic. There is a single platform between the B2B2C, wherein a platform allows, through a single access for each stakeholder, the ability to each have control over availability dates and pricing specifications to a plurality of merchants and/or subscription outlets or channels. Subscription channels can support micro-subscriptions with diversely curated and priced offerings, including acceptance of crypto-currency. The delivered media assets may include content associated with an exercise apparatus, including content for an exercise session including computer generated content and computer augmented content created in response to exercise session data.
US12214258B2	Wearable computer with fitness machine connectivity for improved activity monitoring A method of generating a calibration factor is described. In an example, the method may include establishing a wireless communication connection with a fitness machine. The method may also include obtaining first machine data from the fitness machine. The first machine data may specify a type of the fitness machine. The method may also include initiating a workout session on the wearable computer based on the first machine data. During the workout session, the method may also include obtaining sensor data, obtaining second machine data, and determining the calibration factor based on the second machine data and the sensor data. The method may also include generating a workout session summary based on the calibration factor.
US12214256B2	Device for efficiently extracting adaptively selected contactless multi-player heart rates The present disclosure discloses a device for efficiently extracting adaptively selected contactless multi-player heart rates includes: an acquisition module that covers a court to obtain videos from a plurality of angles during players training; a valid player obtaining module configured to remove players with low contributions to training and games in the videos; a facial ROI extraction module configured to detect whether the facial ROIs of valid players contain perfect eye region features, and use the facial ROIs containing the eye region features as best facial ROIs for heart rate extraction; and an analysis and estimation module configured to analyze the detected best facial ROIs by using blind source separation, and estimate a RGB signal by a JADE algorithm to obtain the heart rate values of the valid players.
US12214254B2	Systems and methods for measuring and/or analyzing swing information In a first aspect, a method for monitoring a golf swing is provided that includes coupling a mobile telephone to a golf club and employing the mobile telephone coupled to the golf club to monitor acceleration of the mobile telephone as the mobile telephone swings while a user swings the golf club, collect acceleration information based on the monitored acceleration of the mobile telephone as the mobile telephone swings, analyze the collected acceleration information to determine one or more characteristics of the golf swing based on the collected acceleration information, and output information regarding the one or more characteristics of the golf swing on the display of the mobile telephone. Numerous other aspects are provided.
US12214250B2	Devices for exercise apparatuses A computing system for determining osteogenic loading from an exercise apparatus for performing an exercise is provided. The exercise apparatus includes a loading interface, a frame, a linear adjustment system interposing between and fixedly coupled to the loading interface and the frame, and a sensor coupled to the linear adjustment system. A position of the loading interface of the exercise apparatus is adjusted through a movement of the linear adjustment system at one or more intermediate positions of a plurality of functional positions of the loading interface. A force exerted by a subject on the loading interface at the position in the one or more intermediate positions is received. A measurement of the force exerted by the subject on the loading interface at the position in the one or more intermediate positions from the sensor is obtained. A corresponding osteogenic loading for the force exerted by the subject is determined.
US12214244B2	Adjustable squat bar An exercise bar includes a center bar; a pair of weight bars, each weight bar rotatable relative to the center bar about a pivot axis to a plurality of camber positions; a pair of support bars configured to rest on a user's shoulder, each support bar extending from one of the weight bars; and a locking mechanism for locking the weight bars in any of the plurality of camber positions.
US12214243B2	Portable exercise device A portable exercise device that may be arranged in a number of different orientations and positions on the body of an individual. The portable exercise device includes a resistance assembly that enables a resistance of the portable exercise device to be adjusted.
US12214242B2	Kinetic workout station A strength machine includes a housing having at least two openable or detachable housing shells, a support structure coupled to the housing, a rotatable flywheel mounted on a shaft supported by the support structure, the flywheel being situated between the two housing shells, the flywheel changing its direction of rotation while in operation, a strap- or belt-shaped flexible pulling element attached to the shaft, a hand grip which forms part of or is attached to the flexible pulling element, and an attachment module coupled to the housing, for securing the strength-training machine to an external support.
US12214235B2	Surrogate foam test system A fluid distribution system includes a first flow meter configured to be positioned along an agent line, a metering valve configured to be positioned downstream of the first flow meter, a second flow meter configured to be positioned downstream of the first flow meter and an eductor, and a controller configured to selectively operate the fluid distribution system in a testing mode where the controller is configured to acquire a first flow rate of a fluid flowing through the first flow meter and a second flow rate of the fluid flowing through the second flow meter, determine a performance characteristic based on the first flow rate and the second flow rate, and modulate a current setting of the metering valve from a first setting to a second setting and conduct the testing mode sequence again at the second setting to verify the fluid distribution system is performing properly.
US12214233B2	Wildfire defense spraying system for spraying environmentally-clean water-based liquid fire inhibitor to proactively form thin fire-inhibiting potassium salt crystalline coatings on sprayed property surfaces prior to the presence of wildfire A wildfire defense spraying system installed on a property with combustible surfaces and adapted for spraying the property and combustible surfaces with an environmentally-clean water-based liquid fire inhibitor for defending against wildfire by inhibiting fire ignition and flame spread caused by hot flying wildfire embers created during a wildfire storm. The wildfire defense system includes: a storage tank containing an environmentally-clean liquid fire inhibitor comprising a majority amount of tripotassium citrate (TPC) and minor amount of triethyl citrate (TEC) dissolved in a major amount of water according to a prespecified formulation, wherein the environmentally-clean water-based liquid fire inhibitor remains stable without the formation of solids at expected operating temperatures, and ready for immediate spraying on combustible surfaces. A hydraulic pump system is connected to remote power control switch employed to supply electrical power to the hydraulic pump, and remotely activated. A plurality of spray heads is mounted about the property, in fluid communication with the storage tank, and supplied with environmentally-clean water-based liquid fire inhibitor by the hydraulic pump system. During operation, the spray heads spray liquid fire inhibitor from the storage tank forming a spray pattern that covers the property and combustible surfaces to be defended against wildfire embers. When the hydraulic pump system completes pumping and spraying the environmentally-clean water-based liquid fire inhibitor in the storage tank, the hydraulic pump system automatically shuts off, and as water molecules in the sprayed environmentally-clean water-based liquid fire inhibitor evaporate to the environment, thin potassium salt crystalline coatings form on the sprayed combustible property surfaces, inhibiting fire ignition and flame spread in the presence of wildfire.
US12214227B2	Modular portable multi-crew life support system A modular, multi-crew life support system and a method of assembling the system involve a fan to draw in ambient air. The system includes one or more assemblies that produce conditioned air from the ambient air, and a housing to support an oxygen source. The system also includes a port configured as an inlet from the oxygen source to augment the conditioned air, and a duct to disperse a result of augmenting the conditioned air as output air to support two or more occupants of an enclosure.
US12214225B2	Methods for fixing hair and skin A method of treating keratin of a person is disclosed. The method includes contacting the keratin with a composition comprising a compound having a chemical structure of
US12214223B2	Noninvasive tissue displacement control and monitoring for neuromodulation The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.
US12214217B2	Device and method for supporting tissue undergoing radiation The device can be used in a method to protect tissue in the gastrointestinal tract of a patient during radiation therapy, the method comprising positioning a biodegradable device to cover a perforation at a perforation site on a tissue of a patient prior to applying radiation therapy, closing the perforation through surgery, and securing the biodegradable device to cover the perforation site, so that the biodegradable device protects the tissue adjacent to the perforation site during radiation therapy. Wherein the biodegradable device is a biodegradable tubular straw or surgical patch. The surgical patch is a medical device made of tissue engineered materials designed to cover, repair, or augment damaged or weakened tissue or organs during surgery.
US12214214B2	Remote medical device alarm A remote alarm for use with a wearable medical device. The remote alarm is configured to receive alarms, voice messages and prompts issued by the wearable medical device and to repeat those alarms, voice messages and prompts in a manner that can more easily be perceived by a patient wearing the wearable medical device or a bystander. The remote alarm can be configured to receive a communication from the wearable medical device, and in response, to identify one or more messages to be provided to the patient or a bystander. The messages may be provided audibly, visually, tactilely or combinations thereof. The remote alarm may further be configured to take certain actions depending upon the content of the communication, such as sending a telephone message to alert emergency personnel to the identity, location and medical condition of the patient, or sending an email.
US12214207B2	Optimized vector selection for a multi-axis accelerometer in an implantable medical device The present disclosure relates to a medical system, comprising at least an implantable medical device, and a multi-axis accelerometer comprised by the implantable medical device for measuring an acceleration of the implantable medical device along a plurality of vectors, wherein the multi-axis accelerometer is configured to provide for each vector a signal indicative of the acceleration of the implantable medical device in the direction of the respective vector. The medical system is configured to assess said signals to automatically select or propose a vector of said plurality of vectors that comprises the best alignment with a pre-defined vector.
US12214201B2	Method for adaptive control of a medical device using Bayesian optimization Systems and methods for adaptively controlling an electrical stimulation device, such as a closed-loop stimulation device, based in part on a Bayesian optimization of the operational parameters of the device are described. An adaptive dual control of the stimulation device can be provided. In a first control loop parameters are extracted from signals recorded from the subject by the stimulation device, and in a second control loop a Bayesian optimization is implemented with a hardware processor and memory to compute updated operational parameters for the stimulation device. As noted, the stimulation device is an electrical stimulation device, and may be a closed-loop stimulation device. Such devices can be used for deep brain stimulation (“DBS”), cardiac resynchronization therapy (“CRT”), and other electrophysiological stimulation applications.
US12214197B2	Apparatus for management of a Parkinson's disease patient's gait A gait management apparatus applies stimulation to a user suffering from a neurological disease (such as Parkinson's Disease) gait dysfunction. Motion sensors are arranged to be worn by a patient, and electrical stimulation electrodes are on the legs for stimulation. A controller receives motion sensing signals, and processes these signals to generate stimulation signals for operation of the electrodes to stimulate limb movement upon detection of a gait abnormality. There may be a user actuator for user actuation of electrical stimulation, and the inputs may be a series of taps. The controller may provide signals to prevent occurrence of freezing of gait when it senses that a patient is walking or has an intention to walk. Also, it may apply stimulation at an intensity level which is insufficient for functional muscle stimulation but sufficiently high to trigger activation of efferent nerves.
US12214195B2	Implantable cochlear system with inner ear sensor Cochlear implant systems can include an inner ear sensor configured to receive a stimulus signal from the cochlear tissue of a wearer and generate an input signal based on the received stimulus signal. The inner ear sensor can be configured to detect pressure, for example, within a wearer's cochlear tissue and generate an input signal based on the detected pressure. The inner ear sensor can be integrated with a cochlear electrode implanted in the cochlear tissue. Systems can include a signal processor programmed with a transfer function and configured to receive an input signal and output a stimulation signal based on the received input signal and transfer function. Systems can include an implantable battery and/or communication module in communication with the signal processor. The implantable battery and/or communication module can be configured to interface with and update the transfer function of the signal processor.
US12214194B2	Optimization tool for auditory devices A system comprises an auditory device processor, an auditory device output mechanism, an auditory input sensor, a database including a reference bank of environmental sounds and corresponding sound profiles, and a memory. The auditory device processor is configured to: while the auditory input sensor is detecting a first environmental sound, receive a sound selection from the user, wherein the sound selection is associated with the first environmental sound; store a first sound profile in the reference bank corresponding to the first environmental sound; receive a second environmental sound detected by the auditory input sensor; analyze a frequency content of the second environmental sound; compare the frequency content of the second environmental sound with the reference bank of environmental sounds and corresponding sound profiles stored in the database; in response to the comparison, select one of the sound profiles corresponding to the second environmental sound; and automatically adjust the parameter settings.
US12214192B2	Band with built-in stimulator A system includes a collar that is worn around a neck of the user. A stimulator is coupled to the collar such that the stimulator is positioned adjacent to an airway of the user. The sensor is coupled to the collar and configured to generate data associated with the airway of the user. The memory is coupled to the collar and storing machine-readable instructions. The control system is coupled to the collar and includes one or more processors configured to execute the machine-readable instructions to determine, based at least on an analysis of the generated data, that the user is currently experiencing an apnea event. In response to the determination, the control system causes the stimulator to provide electrical stimulation, at a first intensity level, to one or more muscles of the user that are adjacent to the airway to aid in stopping the apnea event.
US12214188B2	Neurological stimulation lead anchors and associated tools, and methods A lead anchor comprising a longitudinally extending anchor body and a retainer. The longitudinally extending anchor body having a lumen positioned to receive a spinal cord lead therethrough and having a retainer pocket intersecting the lumen. The retainer is positioned in the retainer pocket. The retainer comprises a first grip member having at least one first aperture, a second grip member having at least one second aperture, and at least one U-shaped resilient portion connecting the first and second grip members.
US12214187B2	Surgical electrode and lead for use with implanted pulse generator and method of use An implantable pulse generator is provided comprising a non-metallic shell adjacent a header. The header abuts an optical window in the shell. The header aligns a series of surgical or percutaneous leads with the optical window. The leads incorporate optical fibers, electrodes and contacts which distribute stimulation signals. Behind the optical window, a set of optical devices is provided which transmit or receive light from the fibers. Signal processors are provided to interpret the signals from the optical fibers, and to mitigate a continuous inductive charging function.
US12214180B2	Pre-filled syringe safety devices and injectors, systems, and methods of use A prefilled syringe safety device and injector for use with a syringe. The prefilled syringe safety device and injector includes a cartridge, a casing, a tube, a biasing member, a ring and a plunger slider. The cartridge supports the syringe therein. The cartridge is supported within the casing. The tube includes a tube distal end. The tube is slidably engaged with the cartridge and can be in an extended state and in a retracted state. When in the retracted state, the needle of the syringe extends beyond the tube distal end and the casing distal opening. The biasing member is engaged with the cartridge and the tube so as to bias the tube in the extended state. The ring includes a protrusion and is engaged with the tube and the biasing member. The protrusion is positioned within the track. The plunger slider engages with the plunger of the syringe.
US12214176B2	Auto-injector An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
US12214174B2	Data collection device for attachment to an injection device Data collection devices for attachment to injection devices are disclosed. In one embodiment, the data collection device includes: a body attachable to a dial member of the injection device, a sensor arrangement comprising a sensor and a scale, and a processor. The sensor is configured to detect a rotation of the body relative to a trigger of the injection device. The processor is configured to detect a rotation of the body relative to the trigger. One of the sensor and the scale is arranged in or on the body and wherein the other one of the sensor and the scale is located on the trigger or is rotationally lockable to the trigger configured to detect a rotation of the body relative to the trigger.
US12214172B2	Auto-injector An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
US12214160B2	Method and apparatus for subretinal injection In certain embodiments, an apparatus is provided for performing a subretinal injection into a subretinal space between a retina and a retinal pigment epithelium of an eye. The apparatus includes an injection needle having a proximal end and a distal end, the distal end configured to be insertable into the subretinal space at a position on a surface of the retina. The apparatus includes a multi-lumen tubing having a distal end coupled to the proximal end of the injection needle and a proximal end coupled to a fluid control unit. The apparatus includes a stabilizer configured to immobilize the injection needle at the position on the surface of the retina. The fluid control unit has a plurality of fluid reservoirs containing a non-treatment solution, a treatment solution, and a working fluid which are injectable into the eye via separate lumens of the multi-lumen tubing.
US12214149B2	Applicator system containing a microneedle array which comprises an active ingredient for wound healing The invention relates to an applicator system comprising a microneedle array and to the use thereof for the intradermal delivery of active ingredients, and in particular of medicinal drugs, wherein this microneedle array is suitable for penetrating the skin of humans or animals and includes at least one active ingredient for wound healing.
US12214146B2	Controlled release of a hydrophilic agent from a coated surface The present invention is an implantable medical device comprising (i) a base coat layer having an inner and outer surface, the inner surface of the base coat layer contacting the implantable medical device; (ii) a top-coat layer of a hydrophilic polymer chemically crosslinked and covalently bonded to the outer surface of the base coat layer, the hydrophilic polymer comprising an anionic polyelectrolyte; and (iii) an amount of a hydrophilic cationic drug agent added to the top-coat layer sufficient to provide an effective dosage of the drug agent for delivery to a patient, whereby the hydrophilic cationic drug agent is initially adsorbed into the anionic polyelectrolyte of the top-coat layer and the hydrophilic cationic drug agent having a release rate after the medical device is implanted within a patient's body.
US12214145B2	Catheter, composition for catheter, production method therefor Provided is foley catheter and a composition for producing a foley catheter which is inserted in vivo and a method for producing the same, which the composition consists of the materials which carbon nanotube polymer (CNT Polymer) bonded a carbon nanotube and zinc oxide (ZnO) is combined with a silicon, wherein from 1.0 to 2.2 parts by weight of the said carbon nanotube polymer are combined with 100 parts by weight of silicon.
US12214143B2	Devices for monitoring movement of a secured catheter during a procedure A device for securing and monitoring movement of a catheter includes a film having an adhesive disposed on a body-facing surface for securing the film to a body. The device also includes a base mounted on the film, the base comprising a first portion of a guide channel for receiving the catheter. A cover is coupled to the base via a hinge, the cover comprising a second portion of the guide channel, the cover further comprising a rounded portion extending from a distal end of the cover, wherein in the closed configuration, the catheter is completely enclosed by the rounded portion and the first and second portions of the guide channel. The device also includes a positional shift indicator fixedly attached to the catheter and configured to indicate positional shifts by the catheter within the guide channel.
US12214140B2	Adaptive digital therapy system with real-time emotional state analysis and symbolic language communication The present invention relates to a system and method for providing adaptive digital therapy, enhancing the emotional well-being of users through the analysis and translation of expressive and physiological states. Aspects of the invention are directed to identifying the neuroplastic window via user inputs, with or without the aid of psychedelics. This invention is particularly suited for supporting psychoactive therapies involving compounds such as 5-HT2A agonists, dissociatives, and empathogens, as well as applications beyond psychoactive treatments. By utilizing multi-modal deep learning methods, the system captures a wide array of user inputs, including text, speech, vision, symbols, and brain waves, to form a dynamic user representation. This representation is then used to provide real-time, tailored generative communications informed by established psychological therapeutic frameworks. The invention features a closed-loop feedback system through an access module, enabling continuous data relay, patient response metric derivation, and transmission of emotional optimization communications. The system also introduces novel communication methods, including symbolic language input, to articulate complex experiences and extends its capabilities to include natural emotional states, broadening its therapeutic applicability.
US12214139B2	Pulsating positive airway pressure devices and methods of use Methods and systems for delivery of pulsated air to a user using a device including a flow generator to generate a continuous air flow, a first actuator comprising a pulsated flow delivery mechanism configured to generate a pulsated air flow from the continuous air flow based on a pre-determined duty cycle to vary a frequency of the pulsated air flow, a user interface configured to generate and deliver vortices of pulsated air to the user at the frequency of the pulsated air flow, and a set of tubing to couple the flow generator, the first actuator, and the user interface.
US12214138B2	Respiratory humidification device A respiratory humidification device includes: a casing; a separator wall to divide an interior space into filling and humidification chambers, wherein a bottom edge of the separator wall leaves a space between it and the casing bottom to define a passage allowing water to flow atop the casing bottom between the chambers, and enabling the water level to rise enough to block the passage to prevent respiratory gas from passing therethrough; a valve and float within the filling chamber to control water flow into the filling chamber to prevent the water level from rising higher than a threshold; and wherein an outer wall of the casing and the separator wall cooperate with the water surface within the humidification chamber to define an elongate tube-like pathway through which respiratory gas proceeds along a path extending generally parallel to the water surface within the humidification chamber to be humidified.
US12214135B2	Nasal cannula The disclosure relates to a nasal cannula comprising a port configured for delivery of a medicament into a flow of a fluid being delivered by the nasal cannula to a user and/or configured for interfacing with a medicament delivery device or an instrument. The disclosure also relates to a nasal cannula comprising an asymmetric profile to reduce an amount of occlusion of one nare of a user to provide access for an instrument to the nare with the nasal cannula in use.
US12214134B2	Oral and nasal sealing interface pad An oral and nasal sealing interface pad including a rigid part and a lining pad. The rigid part has a circular opening on one side and a joint part on the other side; the lining pad is fixedly connected to the joint part and is located below the user's nose. The lining pad includes a nasal area corresponding to and abutting the user's nasal tip and a mouth area corresponding to and surrounding the user's mouth. The space enclosed by the nasal area is connected to the space enclosed by the mouth area, together forming an integrated respiratory chamber. The nasal area includes a nasal tip area and an alar area. The nasal tip area has at least one thin area for accommodating the user's nasal tip, and the nasal tip area is equipped with a first wing for abutting against the user's columella.
US12214132B2	Endotracheal tube guard with optional holding system and optional sensor Disclosed embodiments of an endotracheal tube (ETT) guard system help to hinder self-extubation of the ETT of an awake patient who may reflexively attempt removal, but also allow early mobilization and exercise necessary for preservation of muscle strength. Embodiments may include an ETT holder, which may be generic ETT holders offered by various medical device companies, or a specially configured ETT holder as described herein. Embodiments also may include a sensor that alarms when the ETT guard is moved beyond pre-set motion thresholds.
US12214129B2	Laryngeal mask airway device and method for administering a medicament through a laryngeal mask airway device A laryngeal mask airway device includes an airway tube and a laryngeal mask placed at a distal end of the airway tube. The distal end of the airway tube opens inside the laryngeal mask. The device includes a connector placed at a proximal end of the airway tube. The connector is in fluid communication with the laryngeal mask through the airway tube and is configured to be connected to a ventilation equipment. The device includes a movable element placed in the laryngeal mask and configured to steer a tip of a catheter passing through the airway tube. The device further includes a control element mounted on the proximal end of the airway tube and a motion transmission device operatively connected to the movable element and to the control element to move the movable element and to steer the tip of the catheter by acting on the control element.
US12214128B2	Blood pressure measuring apparatus, method and program for measuring blood pressure, and respiration assistance apparatus According to one embodiment, a blood pressure measuring apparatus includes a blood pressure measurement unit, a warning estimator, and a signal output unit. The measurement unit measures blood pressure of a target person. The estimator monitors variation of blood pressure measured by the measurement unit and estimates the variation of the blood pressure as a sign of a blood pressure increase associated with an onset of sleep apnea syndrome if the blood pressure continuously decreases to a preset threshold or lower for a predetermined time or longer. The output unit outputs a sign notification signal to outside of the apparatus if the sign is estimated by the estimator.
US12214126B2	Automatic system for the conservation of gas and other substances A system for conserving oxygen and other gasses supplied to a recipient. A supply conduit supplies gas from a source to a reservoir, which retains a volume of gas at ambient pressure. A conduit supplies gas from the reservoir to the recipient, and an inflation detection system detects when the reservoir is below a state of inflation and when the reservoir is inflated to the state of inflation. A valve system prevents gas from flowing from the source and into the reservoir when the reservoir is at the predetermined state of inflation, and the valve system permits gas to flow from the source and into the reservoir when the reservoir is below the predetermined state of inflation whereby gas within the reservoir can be continually replenished without pressurization above ambient pressure. The inflation detection system can be an electro-mechanical system. Alternatively, the inflation detection system can be a contactless system.
US12214124B2	Support for a breathing assistance apparatus and/or accessories A support apparatus for a breathing assistance apparatus has a base, a mount, and a handle. The mount is configured to releasably couple the support apparatus with the breathing assistance apparatus by lowering the breathing assistance apparatus relative to the mount. The handle is configured to enable the support apparatus and a releasably coupled breathing assistance apparatus to be lifted and carried by a user.
US12214121B2	Dry powder inhaler The present invention provides an inhaler comprising a housing which contains a blister strip having a plurality of blisters which contain powdered medicament for inhalation; a mouthpiece through which the medicament is inhaled by a user; an indexing wheel for indexing the blister strip; an opening mechanism for opening the blisters; an actuator which is movable between a first position and a second position in order to operate the indexing wheel and the opening mechanism; and a coupling mechanism for coupling the actuator to the indexing wheel so that the indexing wheel rotates together with the actuator during part of the motion of the actuator; characterized in that the coupling mechanism comprises a shuttle that rotates on the same axis as, and translates axially relative to, the indexing wheel.
US12214119B2	Electrical condensation aerosol device The present invention provides a method for producing condensation aerosols for the treatment of disease and/or chronic, intermittent or acute conditions. These condensation aerosols are produced from drugs including temperature sensitive drugs and small molecule drugs that are coated onto a foil substrate which is heated via electrical resistance heating at precisely controlled temperature profiles with controllable ramp-up and heating rates to vaporize the coated drug which subsequently condenses to form aerosol particles. These condensation aerosols have little or no degradation products. Kits comprising a drug and a device for producing a condensation aerosol are also provided. Also disclosed, are methods for using these aerosols and kits and methods of making the aerosols.
US12214116B2	Methods and systems for providing control stability in a vacuum generation system using cascade proportional-integral-derivative (PID) controller Certain embodiments provide a vacuum generation system with a cascade PID controller, a proportional valve, and a vacuum generator. The cascade PID controller allows the vacuum generation system to control the operating range of supply air pressure that is provided to the vacuum generator. By controlling the operating range of the supply air pressure, the vacuum generation system is able to avoid entering the decreasing or non-monotonic region of the vacuum generator.
US12214114B2	Flow synchronization devices, methods, and systems A parameter for controlling an inlet pump speed in a hemofiltration system is derived from fitting a line to multiple data points of pressure versus pump speed. The pressure is measured in a channel connecting an inlet pump to an outlet pump. First, the inlet pump operates and the pressure is sampled until it is stabilized, then the inlet pump speed is increased and pressure is measured to obtain a data point. Subsequently the inlet pump speed is decreased and pressure is measured to obtain another data point. A line is fit through the data points to obtain the parameter.
US12214113B2	Dialysis system pump with connector A disinfecting connector of a dialysis system, including: a disinfecting chamber positioned within an internal lumen of the disinfecting connector, including: at least one barrier between the internal lumen and a tube connected to the disinfecting connector; a disinfecting material that is approved for usage inside the body; wherein penetration of a second connector through the at least one barrier causes or allows flow of said disinfecting material into the second connector in an amount and surface coverage sufficient disinfects a flow path between the second connector and the tube.
US12214111B2	Positioning of sensors for sensor enabled wound monitoring or therapy Embodiments of apparatuses and methods for determining a positioning of sensors in a wound dressing are disclosed. In some embodiments, a wound monitoring and/or therapy system can include a wound dressing and a plurality of sensors configured to measure one or more wound characteristics. The wound monitor system can also include at least one positioning device configured to indicate position and/or orientation in the wound of a sensor of the plurality of sensors. In some embodiments, a detector can be configured to determine, based on the positioning data, the position and/or orientation in the wound of the sensor of the plurality of sensors. In some embodiments, the plurality of sensors can be positioned on a strip or string of material in communication with the positioning device.
US12214110B2	Antimicrobial system with distributed disinfection controls, integrated arming switch sensors, and streamlined safe lockout protocol Antimicrobial system including a luminaire configured to emit a disinfection light in an ultraviolet band for disinfecting a vicinity of a target pathogen. A switching device that includes a primary relay pack. A control station, an integrated arming switch, a room sensor. The integrated arming switch has a communication interface, an integrated room sensor, a processor, and integrated arming switch programming in a memory. Execution of the integrated arming switch programming by processor configures the integrated arming switch to perform the following functions. Based on a second input from the operator, produce a visual inspection signal. In response to the integrated room sensor detecting occupancy of the vicinity of the physical space by the human, produce a room state signal. Send, via the communication interface, the visual inspection signal to enable the primary relay pack to control power to the luminaire to emit the disinfection light.
US12214108B2	Water-based hydrogel blend coating and method of application to elastomeric articles A water-based hydrogel polymer coating and a method of application to natural rubber or other elastomeric latex products are provided. The water-based hydrogel polymer is mixed with a blend of at least one elastomeric material to provide a hydrogel polymer blend composition. The water-based hydrogel polymer blend composition is applied in a single application to an elastomeric article, such as gloves, without additional solvents in the polymer blend composition and without a separate acid or chemical priming step. The water-based hydrogel coating herein provides increased lubricity to facilitate improved wet and dry donning of the elastomeric article.
US12214107B2	Drug-coated medical devices Disclosed herein is a drug-coated medical device in the form of a balloon having an inner surface and an outer hydrophobic surface, an adhesion balance layer directly on the outer hydrophobic surface of the balloon, comprising a hydrophilic polymer and/or a hydrophilic compound where the hydrophilic compound has a molecular weight of less than 1,000 Daltons, and a therapeutic layer directly on the adhesion balance layer comprising a therapeutic agent and a pharmaceutically acceptable carrier, wherein the therapeutic agent is a hydrophobic therapeutic agent with one or more hydrogen-bonding groups and is provided as discrete drug particles in the therapeutic layer, the drug particles have at least one dimension that is less than 25 μm and are uniformly distributed on the surface of the balloon, and the pharmaceutically acceptable carrier is hydrophilic and has a molecular weight of less than 1,000 Daltons. A process to make the drug-coated medical device and uses thereof are also disclosed.
US12214104B2	Photo-reactive inks and thermal-curable materials made therefrom Provided herein photo-reactive inks, thermal-curable materials and objects (e.g., medical implants, scaffolds, devices, etc.) made therefrom, and methods of preparation and use thereof.
US12214099B2	User equipment having multiple subscriber identity modules with improved suspend / resume operation Devices and associated methods for operating a dual-subscriber identity module (SIM) dual-standby (DSDS) user equipment device (UE) configured with a first SIM and a second SIM. The UE performs communications with a first cellular network using the first SIM and a first radio resource control (RRC) connection, and receives a request to perform a higher priority communication using the second SIM. In response to the request to perform the higher priority communication, the UE transmits a request to the first network to suspend the first RRC connection. After transmission of the request to suspend the first RRC connection, the UE receives a message from the first network to place the first RRC connection in an inactive state, and initiates a timer, wherein the timer is used to determine whether the first RRC connection remains in the inactive state or transitions to an idle state.
US12214096B2	System and method for safely eradicating pathogens A system for eradicating pathogens is disclosed. A lamp is provided that emits a far-ultraviolet C (far-UVC) light generates an irradiation zone. A biometric sensor determines whether an individual is present in the irradiation zone. The biometric sensor signals a processor to determine whether the individual has been exposed to a threshold limit of far-UVC light. The processor determines whether the time an individual has been in the irradiation zone exceeds a threshold limit. If the individual has been in the irradiation zone a period of time exceeds the threshold, the lamp is deactivated. A pathogen detection sensor provides user feedback of the existence pathogens and signals the processor to terminate irradiation or provide user feedback to terminate irradiation. The system and method are included in a passenger compartment of a vehicle to eradicate pathogens on surfaces and aerosol. Threshold limits allow eradication while the vehicle is occupied.
US12214090B2	Kind of wound dressing for haemostasis A wound dressing is which has haemostatic, coagulation-promoting and biocidal properties and can therefore be utilized particularly for acute wound care. Typical areas of application for acute wound care are, for example, the treatment of gunshot wounds. The wound dressing features selected halloysites which, for example, are applied to textile fibers or non-woven materials.
US12214087B2	Thermostable quick-dissolving thin film The present invention relates to thermostable quick-dissolving thin films comprising a biological moiety and an excipient mix which are suitable for the formulation of biological moieties such as viral vaccines, to methods for manufacturing such thermostable quick-dissolving thin films, and to their use in therapy. The excipient mix comprises one or more water-soluble polymer(s), a sugar selected from sucrose, trehalose and a combination thereof, a metal ion, a carboxylate, and a buffering agent.
US12214086B2	Surface functionalized, host-guest polymer nano-assemblies and methods thereof The invention generally relates to polymer-based nano-structures. More particularly, the invention relates to novel, surface-functionalized, guest-host polymer nano-assemblies and nano-delivery vehicles useful in diverse fields including drug delivery, diagnostics and specialty materials. The nano-assemblies and nano-delivery vehicles of the invention are afforded via simplify and reliable approaches.
US12214084B2	Enteric hard capsule An object of the present disclosure is providing a hard capsule made of a hard capsule film having enteric properties that can be molded by a cold gel method. An enteric hard capsule comprises a film containing a first component and a second component, and further containing at least one component selected from the group consisting of a third component, a fourth component, and a fifth component, wherein the first component is a nonionic water-soluble cellulose compound having a viscosity value within a range of from 100 mPa·s to 100,000 mPa·s, the second component is an enteric methacrylic acid copolymer, the third component is an enteric cellulose compound, wherein the fourth component is a water-insoluble (meth)acrylic acid alkyl ester copolymer, and the fifth component is at least one kind selected from the group consisting of polyvinyl alcohol, a plasticizer, and a surfactant.
US12214082B1	One pass spray dried lactose Methods for preparing spray dried lactose are provided. Methods include concentrating an aqueous lactose source, crystallizing at least a portion of the lactose in the concentrated lactose source, and forming a crystallized lactose slurry comprising a plurality of lactose particles. Methods include washing the crystallized lactose slurry for a period of time sufficient to reduce an absolute value of a b*-value color of the lactose particles by greater than or about 75%. Methods include wet milling the crystallized lactose slurry, reducing a D50 particle size of the plurality of lactose particles by greater than or about 50%. Methods include spray drying the crystallized lactose slurry, forming a plurality of spray dried lactose particles.
US12214079B2	Micronized lipids The present invention relates to drug delivery vehicles comprising micronized particles that include an active lipid agent, and in particular to micronized lipid particles that comprise an ether lipid such as sn-1-O-eicosanyl-sn-2-palmitoyl-glycerol and its isomers.
US12214076B2	Drug delivery vehicles for atherosclerosis nanomedicine Provided herein are peptide amphiphiles (PAs). In some embodiments, provided herein are targeting PAs comprising a PA backbone and a targeting moiety. In some embodiments, provided herein are therapeutic PAs comprising a PA backbone and a therapeutic agent. In some embodiments, the peptide amphiphiles are co-assembled into nanofibers. In some embodiments, the nanofibers may be used for the treatment of atherosclerosis or related disease.
US12214075B2	Apixaban suspension and preparation method The invention describes a buffered oral aqueous apixaban suspension comprising 0.08-0.20 w/v % micronized apixaban having a pH of 1.5-6.5 and a method for the preparation thereof.
US12214070B2	Cosmetic use of engineered postbiotics comprising bacteriocins and/or endolysins A method for the cosmetic caring of the skin and/or mucosa, comprising applying a postbiotic composition comprising at least one postbiotic and at least one bacteriocin and/or endolysin, wherein the postbiotic is preferably a bacterial lysate preferably obtained from bacteria heterologously expressing the at least one bacteriocin and/or endolysin and wherein the postbiotic and the at least one bacteriocin and/or endolysin have a synergistic effect in the cosmetic caring method.
US12214066B2	Hair care compositions Provided are methods, compositions and kits employing cellulose nanocrystals for hair-straightening treatment. Also provided are methods, compositions and kits employing a resilin, for hair-straightening treatment and/or for maintenance of straightened hair following a hair-straightening treatment.
US12214065B2	Diester cosmetic formulations and uses thereof The present application relates to compounds, formulations, kits and methods of use in the cosmetics field. A cosmetic formulation comprising a diester compound of Formula (I) or Formula (II), or a combination thereof, and one or more cosmetically acceptable carriers or excipients. The structures of compounds of Formula (I) and Formula (II) are shown below:
US12214064B2	Alcohol based sanitizer with improved dermal compatibility and feel Applicants have identified a critical skin benefit package that can be used in liquid alcohol sanitizing compositions that provides lower amounts of skin conditioners in combination with a specific ratio of different emollients that provide improved skin health with chronic repeated use. The package also provides improved skin feel with without a tacky residue upon drying.
US12214059B2	Cleavable radioligands for targeting cell surface receptors and uses thereof The present application relates to a compound or a pharmaceutically acceptable salt and/or solvate thereof comprising one or more circulation enhancing groups, one or more target binding groups, one or more chelating groups, at one least cleavable linker and at least one branching group that is at least trivalent. The application further includes a radionuclide complex or a pharmaceutically acceptable salt and/or solvate thereof, comprising a compound of the application or a pharmaceutically acceptable salt and/or solvate thereof, and one or more radionuclides, and to compositions comprising the compound or the complexes. The present application also includes methods of using the compounds, complexes and compositions for targeting and/or killing target cells. For example, the compound includes a compound of Formula I
US12214054B2	Therapeutic targets for the correction of the human dystrophin gene by gene editing and methods of use Disclosed herein are therapeutic targets for the correction of the human dystrophin gene by gene editing and methods of use.
US12214048B2	Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a TLR peptide agonist for use in medicine The present invention provides a combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, at least one antigen or antigenic epitope, and a TLR peptide agonist for use in medicine, in particular in the prevention and/or treatment of cancer. Moreover, the present invention also provides compositions, such as a pharmaceutical compositions and vaccines, which are useful in medicine, for example in the prevention and/or treatment of cancer.
US12214047B2	FAP-activated proteasome inhibitors for treating solid tumors Disclosed are proteasome inhibitors, fibroblast activation protein (FAP)-activated prodrugs of proteasome inhibitors, and pharmaceutically acceptable salts of the inhibitors and prodrugs. Also disclosed are related pharmaceutical compositions, and methods of using the inhibitors and prodrugs and compositions thereof, for example, in treating cancer or other cell proliferative diseases. In vitro and in vivo methods of quantifying the expression of FAP in a biopsy sample and a mammal, respectively, are also disclosed.
US12214046B2	Protein-loaded PLGA nanospheres The present disclosure provides compositions comprising protein encapsulated nanoparticles, and methods of making said compositions. In an aspect, a composition may comprise a drug delivery vector and a therapeutic substance, wherein the composition elutes at least 1.0 pg of the therapeutic substance per 100,000 particles of the drug delivery vector over a period of time under conditions of a drug delivery vector release buffer, wherein the therapeutic substance, drug delivery vector and drug delivery vector release buffer comprise a solution, wherein the solution is centrifuged and a portion stored at about 1 to 10° C., and wherein the elution of the therapeutic substance is determined by ELISA assay. This disclosure further describes a method of controlling an immunophenotype in a patient suffering from a disease which impacts the immune system.
US12214045B2	Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods Provided are multi-arm polymer conjugates of Toll-Like Receptor (“TLR”) agonists such as TLR 7/8 agonists, as well as related compositions, and methods of making and using such conjugates. Exemplary conjugates are encompassed by Formula I: or a pharmaceutically acceptable salt form thereof, where R, taken together with each Q, is a residue of a polyol, polythiol, or polyamine bearing from 3 to about 50 hydroxyl, thiol, or amino groups; each Q is a linker selected from oxygen, sulfur and —NH; each POLY is independently a water-soluble, non-peptidic polymer; each Xr is independently a linkage-containing spacer moiety; q is a positive integer from 3 to about 50; and each TLR 7/8 AG is a Toll-like receptor 7/8 agonist. Also provided is a method of administering to a patient having cancer (a) an IL-2Rβ-activating amount of a long-acting, IL-2Rβ-selective agonist; and (b) a Toll-like receptor agonist such as a conjugate as described above, as well as related compositions, kits and methods.
US12214042B2	Method for stabilization and delivery of therapeutic molecules A method of treatment is disclosed, comprising administering a composition of Cyclodextrin and reduced, nanonized L-Glutathione to a patient in need of treatment, wherein the L-Glutathione molecule is non-acetylated, non-Esterified, and non-fatty acid attached.
US12214038B2	Compositions and methods for cancer immunotherapy The invention provides compositions and methods for cancer immunotherapy. Specifically, the invention provides an antigen-presenting cell, for example, a dendritic cell that comprises a tumor mitochondrial molecule or a tumor mitochondrial molecule derived from tumor mitochondrial protein lysate or a specific mitochondria derived protein of mitochondrial protein lysate as antigen source.
US12214033B2	Virus purification Described herein are processes for purifying infectious virus particles and uses of protamine in such processes.
US12214032B2	Porcine Reproductive and Respiratory Syndrome vaccine virus The present invention relates to modified, live Porcine Reproductive and Respiratory Syndrome viruses. Viruses were genetically analyzed and selected based on phylogenetic grouping for modification by repeated passage in tissue culture. The modified, live viruses were assessed for the ability to provide protective immunity to heterologous viruses. The modified, live viruses are useful in vaccines, particularly in vaccines which can treat infection of swine by multiple heterologous viruses.
US12214024B2	Use of APC analogue for wound healing The invention relates to wound repair and healing, particularly to dermal or cutaneous wounds including but not limited to acute and chronic wounds, burns and ulcers.
US12214019B2	Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins Embodiments of the invention provide shaped masses comprising one or more drugs such as proteins or polypeptides and methods for forming such shaped masses. One embodiment provides a shaped mass comprising a drug such as a protein or polypeptide having a biological activity in the body of a mammal. The shaped mass is formed by compression of a precursor material comprising the drug wherein an amount of biologically active drug in the mass is a preserved above a minimum level. Drugs which may be incorporated into the shaped mass may include one or more glucose regulating proteins such as insulin, incretins; and immunoglobulins such as TNF-inhibiting antibodies or interleukin neutralizing antibodies. Embodiments of the shaped mass may be incorporated into a tissue penetrating member which is inserted into the intestinal wall allowing for the oral delivery of proteins and peptides which would otherwise be degraded in the intestinal tract.
US12214015B2	Use of c-type natriuretic peptide variants to treat osteoarthritis The disclosure relates to the use of variants of C-type natriuretic peptide (CNP) to treat osteoarthritis, to ameliorate one or more symptoms of osteoarthritis, and to treat disorders having an osteoarthritis component.
US12214013B2	Methods of treatment of arthritis and/or psoriasis with pharmaceutical formulations of etanercept The invention relates to the formulation of pharmaceutical compositions of etanercept. The invention also relates to methods of removing buffer and of formulating pharmaceutical compositions of etanercept.
US12214012B2	Combined preparations for the treatment of cancer Combined preparations for the treatment of cancer are described. The combined preparations comprise: (a) LAG-3 protein, or a derivative thereof that is able to bind to MHC class II molecules; and (b) an anti-neoplastic agent, wherein the anti-neoplastic agent is a platinum-based anti-neoplastic agent or a topoisomerase I inhibitor. Methods for the treatment of cancer using the combined preparations are also described.
US12214011B2	Selective cell death-inducing enzyme system The invention relates to a fusion protein containing a selective cell death-inducing enzyme system for use in the therapy and/or treatment of cancer and tumors in humans and animals, a process, and its use.
US12214009B2	Compositions and methods for improving bruising and rejuvenating skin Compositions and methods for improving bruising, stimulating elastin and/or collagen production, stimulating intrinsic hyaluronic acid production, stimulating adipogenesis, reducing inflammation, or combinations thereof are provided herein. Compositions and methods described herein may be used following a cosmetic procedure.
US12214008B2	Protein interfaces The present disclosure provides methods to treat conditions, including cancer, using compounds that can target resistant cancer cells. The compounds can be used to sensitize resistant cancer cells or decrease the proliferation of cells. The compounds can target proteins in the DNA damage repair pathway leading to a decrease in DNA damage repair in target cells.
US12214003B2	Composition for inducing proliferation or accumulation of regulatory T cells It was found that bacteria belonging to the genus Clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Moreover, the present inventors found that regulatory T cells (Treg cells) induced by from these bacteria suppressed proliferation of effector T-cells. From these findings, the present inventors found that the use of bacteria belonging to the genus Clostridium or a physiologically active substance derived therefrom made it possible to induce proliferation or accumulation of regulatory T cells (Treg cells), and further to suppress immune functions.
US12214001B2	Cancer therapy The present invention relates to the field of cancer therapy. In particular, the present invention relates to a live attenuated Gram-negative bacterium for use in the treatment, reduction, inhibition or control of a neoplastic disease in a subject undergoing or intended to undergo immunotherapy with a checkpoint inhibitor therapy, an adoptive T cell therapy and/or an allogeneic or an autologous CAR-T therapy simultaneously, separately or sequentially with the administration of the live attenuated Gram-negative bacterium.
US12214000B2	Human uterine cervical stem cell population and uses thereof The present invention relates to a method for isolating stem cells comprising preparing a cell suspension from uterine cervix tissue, to the stem cells isolated by said method, and to the conditioned medium obtained from the culture of said stem cells. The invention also encompasses the use of said stem cells or conditioned medium for treating or preventing cancer, precancerous lesions, inflammatory diseases, autoimmune diseases, chronic pathologies or infectious diseases, diseases associated to tissue loss, or for use in diagnostic, prognostic or treatment of fertility disorders, as well as for cosmetic treatment.
US12213995B2	Preparations comprising mesenchymal stem cells and cannabinoids and methods of their use Disclosed are compositions comprising a MSC secretome preparation and cannabinoids and methods of the use of said compositions for the treatment of inflammatory conditions.
US12213993B2	Coated medicinal clay compositions, pharmaceutical compositions, and delivery of cation sources and methods of use thereof Medicinal clay compositions and pharmaceutical compositions containing the same are disclosed. The medicinal clay compositions provide a protective barrier for the clay allowing manufacturing, storage and use that protects the medicinal clay from moisture and hydration that would otherwise prematurely activate the clay. The medicinal clay compositions allow use of medicinal clays in various delivery systems and types of therapeutic compositions, including foams, hydrocolloids, electrospinning, films, pastes, and the like. Methods of preparing the medicinal clay compositions and methods of use are also disclosed. Methods of using the medicinal clay compositions, pharmaceutical compositions, and cation sources to reduce microbial populations on a subject and/or remove chloride from exudate from a tissue or organ in need of treatment are also disclosed.
US12213992B2	Iron containing composition and use thereof A composition comprising an iron salt of a C8 to C24 fatty acid, a citric acid ester of mono- and/or diglyceride or a mixture of citric acid esters of mono- and/or diglyceride and optionally a fatty acid or a mixture of fatty acids, and a method for preparing such a composition. The composition is useful as a medicament for the treatment and prophylaxis of iron deficiency, as a dietary supplement, and as a food additive.
US12213991B2	Preparations for controlled-release of hypochlorous acid Provided are anti-microbial compositions that include an aqueous solution of hypochlorous acid encapsulated in a nanoparticle that allows for controlled release of hypochlorous acid. Also provided are methods of making and using such compositions.
US12213988B2	Methods of treating chronic kidney disease with dapagliflozin The present disclosure is directed to methods of treating patients with chronic kidney disease (CKD), with and without Type 2 diabetes, with an SGLT2 inhibitor, such as dapagliflozin.
US12213977B2	Methods and compositions for treating melanoma The current methods and compositions provide for a novel therapeutic method for treating patients diagnosed with melanoma, especially those that have become resistant to certain other therapies. Accordingly, certain aspects of the disclosure relate to a method for treating melanoma in a subject, the method comprising administering a composition comprising a ferroptosis-inducing agent or other dedifferentiated melanoma-targeting agent to the subject.
US12213975B2	PDE9 inhibitors for treating sickle cell disease The present disclosure relates to PDE9 inhibitors, pharmaceutical compositions comprising the PDE9 inhibitors, and methods of using the PDE9 pharmaceutical compositions for the treatment of sickle cell disease (SCD).
US12213972B2	Stable pharmaceutical compositions of apixaban The present invention relates to stable pharmaceutical compositions comprising apixaban or its pharmaceutically acceptable salts thereof. The present invention further relates to a capsule composition comprising a therapeutically effective amount of apixaban solubilized or dispersed in a pharmaceutically acceptable carrier, wherein the therapeutically effective amount of apixaban ranges from about 0.5 mg/unit dosage form to about 50 mg/unit dosage form. The present invention also provides manufacturing processes thereof and use of the said compositions for prevention, treatment or prophylaxis of disorders in human patients in need thereof.
US12213971B2	Histone deacetylase inhibitors for immunomodulation in tumor microenvironment The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.
US12213966B2	Methods of reducing plasma level of macrophage migratory inhibitory factor in patients Disclosed is a method of reducing plasma level of macrophage migratory inhibitory factor in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of ibudilast, or a pharmaceutical salt thereof.
US12213965B2	Riluzole prodrugs and their use Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.
US12213962B2	Drug resistant immunotherapy for treatment of a cancer The present disclosure is generally related to methods for combining chemotherapy and immunotherapy for the treatment of a cancer. The methods also relate to generating a drug-resistant cytotoxic immune cell line and uses thereof in conjunction with cytotoxic drugs

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