Document Document Title
US12163042B2 High chemical resistant coating as protection against aggressive environment
A curable coating composition precursor comprising a first part (A) and a second part (B). The first part (A) comprises at least one first epoxy curing agent selected from aliphatic and cycloaliphatic amines and any combinations and mixtures thereof. The second part (B) comprises at least epoxy compound selected from bisphenol A and bisphenol F diglycidylether resins, and any combinations and mixtures thereof; at least one polyfunctional epoxy resin; at least one novolac epoxy resin; and optionally, at least one reactive diluent, Part (A) and/or part (B) comprise at least one inorganic phosphate compound.
US12163038B2 Inkjet ink
An inkjet ink for a glass substrate can enable formation of an aesthetic image with high concealability on the surface of the glass substrate. The inkjet ink disclosed here can include: an inorganic solid including an inorganic pigment that develops black and a glass frit; a monomer component having a photocuring property; and a photoinitiator. In the inkjet ink, a volume ratio of the inorganic solid in a case where an ink total volume is 100 volume % can be 35 volume % or less, a volume ratio of the inorganic pigment in the case where a total volume of the inorganic solid is 100 volume % can be 15 volume % or more and less than 90 volume %, and a volume ratio of the inorganic pigment to the photoinitiator can be 6 times or less.
US12163037B2 Aqueous ink, ink cartridge and ink jet recording method
An aqueous ink for an ink jet including a silver particle that contains (i) a first organic monocarboxylic acid having a pKa of 4.60 or more and (ii) a second organic monocarboxylic acid having a pKa of less than 4.60 and having a carbon number of 2 or less.
US12163035B2 White inkjet ink
An example of a white inkjet ink includes: a non-self-dispersed white pigment; from about 0.005 wt % to about 1 wt %, based on a total weight of the white inkjet ink, of an anionic copolymer dispersant having a weight average molecular weight (Mw) ranging from about 125,000 g/mol to about 30,000,000 g/mol; a polymeric binder; and an aqueous vehicle. The white inkjet ink may be used in a textile printing kit.
US12163034B2 Silver ink for low-temperature calcination
A silver ink including silver particles and a protective agent containing at least one amine compound dispersed in a dispersion medium containing, as a main solvent, a solvent having a vapor pressure at 20° C. of 40 mmHg or less and a vapor pressure at 70° C. of 0.09 mmHg or more, in an amount of 80% or more on a mass basis relative to the total dispersion medium. The amine compound has a mass average molecular weight of 115 or less, and the total amount of the amine compound is 1 part by weight or more and 14 parts by weight or less per 100 parts by weight of the silver particles. The silver ink has a moisture content of 500 ppm or more and 50,000 ppm or less and enables a practical metal film to be formed even through calcination at a low temperature of 70° C. or less.
US12163032B2 Composite particles and method for producing composite particles
Provided are composite particles having the optical characteristic of a lower transmittance in the visible light region, i.e., a higher light-blocking performance in the visible light region, and a method for producing composite particles. The composite particles have at least one of Al and Ti formed into a composite with ZrN.
US12163029B2 Wax compositions comprising linear alpha olefins
Novel wax compositions are provided herein comprising at least about 85 wt. % of linear alpha olefins having a carbon number of at least 18, about 8 wt. % to about 40 wt. % of linear alpha olefins having a carbon number of 20, and about 5 wt. % to about 30 wt. % of linear alpha olefins having a carbon number of at least 30. The present wax compositions yield smooth, one-pour container candle waxes and provide ideal container candle burn performance demonstrated by low sooting behavior and a balanced wax consumption.
US12163024B2 Compositions with improved characteristics
The present invention relates to novel compositions comprising cyanate ester resins and substituted bisimides (citraconimides, bisitaconimide, citraconimido-itaconimide, bisnadicimide, bistetrahydroimide and mixtures thereof) as defined in claim 1, and thermoset composite materials based on these compositions.
US12163022B2 Polymers for additive manufacturing
Porous and microporous parts prepared by additive manufacturing as disclosed herein are useful in medical and non-medical applications. The parts are prepared from a composition containing both a solvent soluble component and a solvent insoluble component. After a part is printed by an additive manufacturing process it is exposed to solvent to extract solvent soluble component away front the printed part, resulting in a part having surface cavities.
US12163020B2 Biodegradable polymer blends for manufacturing medical devices
The present invention is directed to bioresorbable polymer blend compositions with tunable mechanical properties for manufacturing medical devices. These blends are multicomponent blends, comprise multiple polymer components and may or may not require additives in the form of fibers or particles for the potential enhancement of mechanical and/or biological properties.
US12163013B2 Polypropylene-polyethylene composition with improved toughness
A polymer composition including: A) 70-97 wt.-% of a polymer blend, including a1) 50-95 wt.-% polypropylene; a2) 5-50 wt.-% polyethylene; B) 3-30 wt.-% of a copolymer of propylene and 1-hexene, including b1) 30-70 wt.-% of a first random copolymer of propylene and 1-hexene; and b2) 30-70 wt.-% of a second random copolymer of propylene and 1-hexene having a higher 1-hexene content than the first random propylene copolymer b1); the weight proportions of components al) and a2) are 100 wt.-%; the weight proportions of components b1) and b2) are 100 wt.-%; component A) has a MFR2 of from 1.0-50.0 g/10 min; component B) has a 1-hexene content in the range of 2.0-8.0 wt.-% based on the overall weight of component B); and the polymer composition is free from plastomers being an elastomeric copolymer of ethylene and 1-octene having a density of from 0.860-0.930 g/cm3.
US12163011B2 Upgraded recycled polyethylene polypropylene blend
A polyethylene-polypropylene composition obtainable by blending a) 80 to 97 wt.-% of a blend (A) comprising A-1) polypropylene and A-2) polyethylene, wherein the weight ratio of polypropylene to polyethylene is from 3:7 to 7:3, and wherein blend (A) is a recycled material, which is recovered from a waste plastic material derived from post-consumer and/or industrial waste; and b) 3 to 20 wt.-% of a compatibilizer (B) being a C2C8 plastomer, having—a DSC melting point of below 75° C. (ISO11357); —an MFR2 (ISO1133, 2.16 kg load at 190° C.) of equal or below 1.5 g/10 min; and—a density of equal or lower than 885 kg/m3 (ISO1183), wherein the ratio of MFR2 (blend (A) (ISO1133, 2.16 kg load at 230° C.)/MFR2 (compatibilizer (B) (ISO1133, 2.16 kg load at 190° C.), is in the range 3.0 to 15; and c) 0 to 1.0 wt.-% of a stabilizer or mixture of stabilizers.
US12163010B2 Cellulose-based admix and processes for fabricating a lightweight concrete substitute and building components for construction
A lightweight insulative and fire-retardant building material and component and manufacturing process are disclosed. The building material is based on cellulose impregnated with clay and can be formed in the form of posts, columns, bricks, blocks, and panels.
US12163007B2 Non-phthalate plasticizer blends for poly(vinyl chloride) resin compositions
The present application discloses a novel plasticizer formulation comprising bis(2-(2-butoxyethoxy)ethyl) terephthalate, bis(2-ethylhexyl) terephthalate, and optionally tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate. The plasticizer formulation is suitable medium to high temperature applications such as wire and cable insulation and jacketing.
US12163005B2 Multilayer and flexible capacitors with metal-ion doped TIO2 colossal permittivity material/polymer composites
Disclosed is polymer-ceramic composite material with colossal permittivity, comprising polymer matrix and ceramic powders embedded in the polymer matrix, wherein a part of the polymer matrix is exposed and adsorbed to the surface of the ceramic powders, and the polymer is electrically insulating. This invention simultaneously achieves large dielectric constant, negligible dielectric loss and high energy density in flexible composite capacitors based on metal-ion co-doped colossal permittivity materials. The host oxides used in this CP system is friendly to the environment, non-toxic and abundant. Additionally, the process developed is relatively simple, low cost and suitable for mass production-scale. Therefore, these composite capacitors have great technological potential for many applications. Compared to the conventional ceramic materials, composites of this invention are lightweight, scalable and easily fabricated into complex shapes towards miniaturization of the compact systems. The additional flexibility feature also possesses broad application prospects in modern electronic and energy storage devices.
US12162996B2 Pre-swelled vinylacetate-ethylene based redispersible polymer powder composition and method for fabricating the same, asphalt composition comprising the same
A redispersible polymer powder composition includes at least one solvent selected from a process oil and an organic solvent, and a vinylacetate-ethylene (VAE)-based redispersible polymer powder pre-swelled by the solvent. The swelling ratio of the vinylacetate-ethylene (VAE)-based redispersible polymer powder exceeds 55%, measured by the equation swelling ratio (%)=[(B−A)/A]×100, where A is the initial mass of the vinylacetate-ethylene (VAE)-based redispersible polymer powder before adding the solvent, and B is the swelled mass of the vinylacetate-ethylene (VAE)-based redispersible polymer powder after adding the solvent and stirring at 300 rpm at room temperature (20° C.) for 30 minutes provided that the mixing ratio of the vinylacetate-ethylene (VAE)-based redispersible polymer powder and the solvent is 1:1 by weight.
US12162995B2 Hydrogels based on functionalized polysaccharides
The present invention relates to functionalized hydrogel networks grafted with at least one moiety for use in numerous fields, from cosmetics to surgery and medicine.
US12162986B2 Silicone rubber composition
A liquid silicone rubber composition contains metallic silicon particles. The content of the metallic silicon particles is 35% by volume or more and 45% by volume or less. The volume average particle diameter of the metallic silicon particles is 1 μm or more and 20 μm or less. The ratio A/B of viscosity A at a shear rate of 0.02/sec to viscosity B at a shear rate of 1/sec of the composition is 2.0 or less.
US12162982B2 Highly bio-based polycarbonate ester and method for producing same
The present invention relates to a highly bio-based polycarbonate ester and a method for producing same. The highly bio-based polycarbonate ester has a bio-based carbon content of 80% or more since the highly bio-based polycarbonate ester is obtained by copolymerization of 1,4:3,6-dianhydrohexitol, which is a bio-based monomer derived from biomass, and 1,4-cyclohexanedicarboxylate and/or terephthalate, and therefore, the highly bio-based polycarbonate ester is not only human-friendly and environmentally friendly, but also advantageous in terms of biodegradability.
US12162980B2 Quinone-containing poly(arylene), methods for the manufacture thereof, and use for electrochemical gas separation
A quinone-containing poly(arylene) includes repeating units of formula (I), (II), (III), (IV), (V), or (VI) as defined herein. The quinone-containing poly(arylene) can be useful in composites, electrode assemblies, electrochemical cells, gas separation systems, energy storage devices, and electrochromic devices.
US12162977B2 Blocked polyisocyanate crosslinking agent, its preparation method and a coating composition comprising the same
Described herein is a blocked polyisocyanate crosslinking agent obtained from reactions of components including a). at least one polyisocyanate selected from the group consisting of aliphatic polyisocyanate, cycloaliphatic polyisocyanate and polyisocyanate-functional polymer and b). at least one beta-diketone. Also described herein is a method of preparing a blocked polyisocyanate crosslinking agent as well as coating compositions including the blocked polyisocyanate crosslinking agent.
US12162976B2 Isopropylidenediphenol-based polyether polyols, processes for their production, and foams produced therefrom
Isopropylidenediphenol-based polyether polyols, processes for their production, foams produced using such isopropylidenediphenol-based polyether polyols, such as PUR-PIR rigid foams, as well as to processes for producing such foams. The polyether polyols have an internal block comprising polymerized ethylene oxide moieties and an external cap comprising polymerized propylene oxide moieties.
US12162974B2 Thermoplastic polyurethanes with high moisture vapor transmission and low water absorption
A novel thermoplastic polyurethane composition is disclosed which comprise the reaction product of a polyisocyanate component, a polyol component, wherein the polyol component comprises a polyester comprising the reaction product of triethylene glycol and/or tetraethylene glycol with a diacid having 6 carbon atoms or fewer, and, optionally, a chain extender component.
US12162972B2 Photostable compositions comprising para-alkoxyl phenyl substituted propenoic acid (APP) copolymer derivatives
The present disclosure relates, according to some embodiments, to photostable photoactive compositions comprising (a) at least one photoactive compound that develops within itself an excited state energy when subjected to UV radiation and (b) a block copolymer comprising a plurality of blocks, wherein the block copolymer is operable to quench the excited state energy.
US12162959B2 Cyclic peptide for treating cancer
The present disclosure generally relates to a circularized peptide for treating cancer. An cyclic peptide is disclosed that has an amino acid sequence selected from Lys-X5-Glu-X1-X2-Gln-Met-Glu-Asp-Asp-X3-X4 (SEQ ID NO: 3), X10-Gly-Glu-Val-Leu-X11-Met-Glu-Asp-Asp-Leu-Val (SEQ ID NO: 4), Lys-Gly-X6-Val-Leu-Gln-Met-X7-X8-X9-Leu-Val (SEQ ID NO: 5), Lys-X5-Glu-X1-X2-Gln-X12-Glu-Asp-Asp-X3-X4 (SEQ ID NO: 9), and X10-X5-X6-Val-Leu-Gln-Met-Glu-Asp-X9-X3-X4 (SEQ ID NO: 10). The amino acids X1, X2, X3, and X4 can be each independently valine, leucine, isoleucine, or alanine; X5 can be glycine, alanine, leucine, isoleucine, or valine; X6, X7, X8, and X9 can be each independently glutamic acid or asparagine; X10 can be lysine or arginine; X11 can be methionine or cysteine; and X12 can be methionine or norleucine. The cyclic peptide can have the amino acid sequence Lys-Gly-Glu-Val-Leu-Gln-Met-Glu-Asp-Asp-Leu-Val (SEQ ID NO: 1).
US12162953B2 Enhanced targeting platform
A platform technology provides particle and nucleic acid conjugates, and compositions thereof, with enhanced targeting to cells, tissues, organs. The particles and nucleic acids and other deliverables contain a synthetic binding protein such as a polypeptide monobody covalently conjugated to the surface of the particle or the nucleic acid, for linking a targeting agent to the particle's surface or the nucleic acid. The particles and nucleic acids and other deliverables optionally contain an antibody non-covalently conjugated to the binding protein, via an Fc domain of the antibody. The particles can include therapeutic agents, diagnostic agents, prophylactic agents, or a combination thereof, to be delivered to desired cells, tissues, and/or organs. The particles and nucleic acids and other deliverables can be used in a wide array of applications including, but not limited to, ex vivo perfusion of mammalian organs and in vivo disease treatment.
US12162952B2 Human-derived anti-(poly-GA) dipeptide repeat (DPR) antibody
Provided are novel dipeptide repeat (DPR) specific antibodies (e.g., human-derived antibodies) as well as synthetic variants and biotechnological derivatives thereof, capable of binding C9orf72 poly-glycine-alanine DPRs, as well as methods and uses related thereto. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.
US12162951B2 Anti-idiotypic antibodies against anti-KLK2 antibodies
In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a KL2B413 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include KL2B413.
US12162950B2 Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
The present invention relates to pharmaceutical compositions and a method of inhibiting metastasis using anti-ROR1 antibodies or antigen binding fragments, ROR1 binding peptides and ROR1 vaccines.
US12162947B2 Fusion protein and its applicaton in preparing medicine for treating tumor and/or viral infection
The present disclosure provides a fusion protein and methods thereof for preparing a pharmaceutical composition comprising the fusion protein and for methods for treating tumors and/or viral infections using said fusion proteins and compositions, wherein the fusion protein comprises an antibody or antigen-binding fragment thereof that specifically binds to human OX40 and a human interferon.
US12162946B2 Antibodies that specifically bind to TL1A and methods of treating gastrointestinal disease
Recombinantly expressed variant antibodies that have enhanced affinity for TL1A and enhanced potency relative to the parent antibody from which they were derived are provided. The antibodies inhibit the interaction between TL1A and the death receptor 3 (DR3). The antibodies, or a composition thereof, may be used to treat one or more of asthma, COPD, pulmonary fibrosis, cystic fibrosis, inflammatory bowel disease, a gastrointestinal disease associated with cystic fibrosis, Crohn's disease, colitis, ulcerative colitis, irritable bowel syndrome, eosinophilic esophagitis, atopic dermatitis, eczema, scleroderma, arthritis, or rheumatoid arthritis.
US12162941B2 Anti-CD112R compositions and methods
The invention provides anti-CD112R antibody compositions and their use in treating cancer.
US12162939B2 Methods for manipulating phagocytosis mediated by CD47
Methods are provided to manipulate phagocytosis of cells, including hematopoietic cells, e.g. circulating hematopoietic cells, bone marrow cells, acute leukemia cells, etc.; and solid tumor cells. In some embodiments of the invention the circulating cells are hematopoietic stem cells, or hematopoietic progenitor cells, particularly in a transplantation context, where protection from phagocytosis is desirable. In other embodiments the circulating cells are leukemia cells, particularly acute myeloid leukemia (AML), where increased phagocytosis is desirable.
US12162937B2 Methods of treating an inflammatory disorder by administering an antibody which binds to a connexin CX43 hemichannel
Methods for identifying compounds that positively regulate connexin 43 hemichannels.
US12162934B2 Gremlin-1 antagonist for the prevention and treatment of cancer
The invention relates to an anti-GREM1 antagonist for use in a method for the treatment or prevention of a cancer.
US12162929B2 Alpha-synuclein single domain antibodies
The present disclosure is directed to single domain antibodies that bind to α-synuclein and the use of these antibodies for the treatment and diagnosis of α-synucleinopathies The present disclosure is also directed to polynucleotides encoding the α-synuclein single domain antibodies, therapeutic vectors comprising these polynucleotides and methods of administering these therapeutic vectors for the treatment of α-synucleinopathies.
US12162928B2 VISTA-Ig constructs and the use of VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
The present invention relates to a fusion proteins comprising regulatory T cell protein, VISTA (V-domain Immunoglobulin Suppressor of T cell Activation (PD-L3) and an immunoglobulin protein (Ig), preferably also containing a flexible linker intervening the VISTA and Ig Fc polypeptide. The invention also provides the use of VISTA polypeptides, multimeric VISTA polypeptides, VISTA-conjugates (e.g., VISTA-Ig), and VISTA antagonists for the treatment of autoimmune disease, allergy, and inflammatory conditions, especially lupus, multiple sclerosis, psoriasis, psoriatic arthritis, multiple sclerosis, Crohn's disease, inflammatory bowel disease and type 1 or type 2 diabetes.
US12162927B1 Compositions and methods for regulating production of an antibody like protein and ribonucleic acid
The present disclosure relates to one or more agents, therapies, treatments, and methods of use of the agents and/or therapies and/or treatments for producing an antibody like protein (ALP) and one or more sequences of miRNA that are complementary to the mRNA of a target, viral-specific protein or proteins. Embodiments of the present disclosure can be used as a therapy or a treatment for a subject that has a condition whereby the production of the APL and decreased production of a target, viral-specific protein or proteins may be of therapeutic benefit.
US12162925B2 DNA-encoded monoclonal antibodies targeting the Ebolavirus glycoprotein
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody to an Ebola viral antigen. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating an Ebola virus infection in a subject using said composition and method of generation.
US12162924B2 Method for the design of fibrillar collagen-mimetic peptide self-assemblies
Novel synthetic human scale collagen triple helices assemblies are disclosed. Methods of making self-assembling collagen mimetic peptides that self-assemble into human scale collagen are also disclosed.
US12162919B2 Oncolytic herpes simplex virus vectors expressing immune system-stimulatory molecules
An HSV vector comprising an expression cassette for one or more of IL12, IL15, and hIL15Receptor alpha subunit is provided.
US12162917B2 B*44 restricted peptides for use in immunotherapy against cancers and related methods
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US12162914B2 Modification and compositions of human secretoglobin proteins
Novel compositions of recombinant human CC10 protein have been generated by chemically modifying the pure protein in vitro. Several new synthetic preparations containing isoforms of chemically modified rhCC10 have been generated by processes that utilize reactive oxygen species and reactive nitrogen species. These preparations contain novel isoforms of rhCC10 which have been characterized with enhanced or altered biological properties compared to the unmodified protein. Preparations containing novel isoforms may be used as standards to identify and characterize naturally occurring isoforms of native CC10 protein from blood or urine and ultimately to measure new CC10-based biomarkers to assess patient disease status. These preparations may also be used to treat respiratory, autoimmune, inflammatory, and other medical conditions that are not effectively treated with the unmodified protein.
US12162906B2 Method for preparing multimeric forms of the hepatitis c virus (HCV) envelope glycoprotein 2 (HCV E2)
A method of preparing extracellularly assembled higher order antigen from a native lower order antigen the method comprising the following steps: (i) contacting lower order antigen with a solution comprising a reducing agent for a time and under 5 conditions sufficient to reduce one or more native cysteines; and (ii) removing or diluting the reducing agent or contacting the reduced lower order antigen with an oxidising agent, to elicit assembly of lower order antigen from (i) into an assembled higher order antigen; wherein at least 10% of the lower order antigen is converted to higher order antigen in step (ii) and whereby the assembled higher order antigen 10 displays at least reduced binding to non-neutralizing antibodies compared to the lower order antigen and retains binding to at least one neutralizing antibody. A method of producing a vaccine composition comprising following the steps of the method and then mixing the assembled higher order antigen with a pharmaceutically or physiologically acceptable diluent, carrier or adjuvant. A composition comprising a 15 higher order extracellularly assembled antigen, wherein the assembled antigen displays at least reduced binding to a non-neutralizing antibody compared to a native control higher order antigen. Use of the assembled higher order antigen to stimulate an immune response or for the detection and/or isolation of an immune cell such as a B-cell specific for the antigen.
US12162904B2 Mannose derivative and application thereof
A mannose derivative is an isonitrile-containing mannose derivative of formula (I), including different linking groups X: A radioactive preparation is provided, including a radiolabeled compound formed by radiolabeling the mannose derivative with a radionuclide. An application of the radioactive preparation in the diagnosis and treatment of tumors is also provided.
US12162903B2 Fluorescent polymerase enzyme substrates having protein shields
Compositions, methods, and systems are provided for fluorescent polymerase enzyme substrates comprising protein shields for improving enzyme photostability in single molecule real time sequencing. Fluorescent polymerase enzyme substrates of the invention have a protein shield between the fluorescent dye moieties and nucleotide moieties of the polymerase enzyme substrate. The polymerase enzyme substrates have a nucleotide component and a dye component, each attached to a protein. The attachments can be covalent. The protein can, for example, prevent the direct interaction of the fluorescent dye moiety with the enzyme when carrying out nucleotide synthesis, preventing photodamage to the enzyme. The polymerase enzyme substrates of the invention can have multiple dyes and multiple nucleotide moieties.
US12162901B2 N-acetylated sialic acids and related sialosides
The present invention provides N-acetyl derivatives of sialic acids, including N-acetyl derivatives of Neu5Ac and Neu5Gc. Methods for preparing related precursors and a variety of sialosides are also disclosed.
US12162900B2 Process for producing agglomerated lignin and use thereof
The present invention is directed to a process to produce agglomerated lignin with a controlled particle size distribution. The agglomerated lignin is essentially free of dust so that the risk of dust explosion is greatly reduced.
US12162899B2 Photochromic germole-fused diarylethenes and production thereof
A germole-fused diarylethene-based compound is presented that includes a germanium-containing five-membered ring structure with an ethene bridge fused to photoactive bis-aryl rings. The germole-fused diarylethene-based compound isomerizes between a ring-open and a ring-closed form upon irradiation and to allow optical storage or photoswitching devices. A method to form the germole-fused diarylethene-based compound is through a rhodium catalyzed coupling between a 1-germyl-aryl-2-boronic ester, 1-germyl-heteroaryl-2-boronic ester, or 1-germyl-alkenyl-2-boronic ester with the 1,2-diarylethyne. The germole-fused diarylethene-based compounds display tunable photophysical properties of the photogenerated closed form, with excellent thermal irreversibility and a robust fatigue resistance.
US12162896B2 Salts and polymorphs of certain MCL-1 inhibitors
The present disclosure relates salts and the crystalline forms of certain 3′,4,4′,5-tetrahydro-2H,2′H-spiro[benzo[b][1,4]oxazepine-3,1′-naphthalene] derivatives as well as pharmaceutical formulations and therapeutic uses thereof. The present disclosure also relates to preparing such salts, crystalline forms and pharmaceutical formulations.
US12162891B2 Glutamate transporter activators and methods using same
The present invention provides compounds useful for treating, ameliorating or preventing a disease or disorder that is caused, induced or characterized by abnormal reduction in glutamate transporter activity or abnormal increase in extracellular CNS glutamate concentration in a subject. In certain embodiments, the compound stimulates a glutamate transporter.
US12162888B2 Carboxamides as ubiquitin-specific protease inhibitors
The present disclosure relates to modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25, pharmaceutical compositions comprising the inhibitors, and methods of using the inhibitors. The modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25 can be useful in the treatment of cancers, among other ailments.
US12162886B2 11,13-modified saxitoxins for the treatment of pain
Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): (Formula (I)); where R1, and R2 are as described herein.
US12162880B2 Pyrimidoheterocyclic compounds and application thereof
A class of pyrimidoheterocyclic compounds, and specifically disclosed is a compound represented by formula (III) or a pharmaceutically acceptable salt thereof.
US12162877B2 Human dihydroorotate dehydrogenase (hDHODH) inhibitors and their use in targeting oncological diseases sensitive to pyrimidine starvation
Compounds of formulae (I) and (II) which are novel inhibitors of human dihydroorotate dehydrogenase (hDHODH) and pharmaceutical compositions containing the compounds of formulae (I) and (II) are provided. A method for treating tumor diseases, including acute myelogenous leukemia (AML), triple-negative breast cancer, PTEN-mutant tumors, and KRAS-driven tumors by administering pharmaceutical compositions containing the compounds of formulae (I) and (II) is also provided.
US12162876B2 Indazole kinase inhibitor and use thereof
Described herein is a kinase inhibitor compound represented by formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug of the compound. Further described herein is a pharmaceutical composition containing the kinase inhibitor compound, as well as methods of using the compound to inhibit cKIT (especially mutant cKIT/T670I), FLT3 (comprising mutant FLT3-ITD), PDGFRα, PDGFRβ, and/or VEGFR2 kinase activity in cells or a subject, and methods for preventing or treating disorders related to cKIT (especially mutant cKIT/T670I), FLT3 (comprising mutant FLT3-ITD), PDGFRα, PDGFRβ, and/or VEGFR2 activity in a subject.
US12162871B2 Inhibitors of VAP-1
Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.
US12162867B2 Inhibitors of RNA helicase DHX9 and uses thereof
Provided are compounds of the Formula (IIB): or pharmaceutically acceptable salts thereof, which are useful for the inhibition of DHX9 and in the treatment of a variety of DHX9 mediated conditions or diseases, such as cancer.
US12162865B2 Methods of treating cancer
The present invention relates to methods of treating cancer by administering the EZH2 inhibitor compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
US12162863B2 Modulators of stimulator of interferon genes (STING)
The present invention relates to compounds of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof that are useful as modulators of STING (Stimulator of Interferon Genes). The present invention further relates to the compounds of formula (I) for use as a medicament and to a pharmaceutical composition comprising said compounds.
US12162862B2 Beta-lactam derivatives for the treatment of diseases
The disclosure provides for compounds and methods for modulating or inhibiting glutaminyl-peptide cyclotransferase-like protein (QPCTL). In one aspect, described herein are compounds of Formulas (I), (Ia), (Ib), (Iaa), (Iab), (Iba), (Ibb), (II), (IIa), (IIb), (IIaa) (IIab), (IIba), and (IIbb), stereoisomer thereof, or salts or solvates thereof. Further provided herein are methods of treating a disease or a condition comprising administering a compound of Formula (I), (Ia), (Ib), (Iaa), (Iab), (Iba), (Ibb), (II), (IIa), (IIb), (IIaa) (IIab), (IIba), or (IIbb), a stereoisomer thereof, or a salt or solvate thereof.
US12162858B2 Quinoline derivatives as inhibitors of AXL/MER RTK and CSF1R
The present invention relates to quinoline derivatives which are inhibitors for Axl/Mer RTK (receptor tyrosine kinase) and CSF1R (colony stimulating factor 1 receptor). These compounds are suitable for the treatment of disorders associated with, accompanied by, caused by or induced by Axl/Mer RTK and CSF1R, in particular a hyperfunction thereof. The compounds are suitable for the treatment of hyperproliferative disorders, such as cancer, particularly immune-suppressive cancer (such as those cancers with an immunosuppression of innate immunity in a tumor microenvironment (TME), refractory cancer and cancer metastases. They are also useful in the treatment of inflammatory diseases and/or neurodegenerative diseases.
US12162855B2 Tetrahydroquinolino derivatives for the treatment of metastatic and chemoresistant cancers
Disclosed herein are compounds of Structural Formula I. Compounds of Structural Formula I inhibit aldehyde dehydrogenase isoform Ia3 (ALDHIa3) and are useful for treating cancer, for example, metastatic or chemoresistant cancer, such as metastatic cancer resistant to chemotherapy. Also disclosed herein are compositions comprising compounds of Structural Formula I and uses of compounds of Structural Formula I for treating cancer, for example, metastatic or chemoresistant cancer.
US12162854B2 Production method for fluoromethyl derivative
A method for producing a fluoromethyl derivative represented by formula (1), the method including step A of reacting an alkene compound represented by formula (2) with a fluorine source represented by formula MFn, in the presence of a hypervalent-iodine aromatic compound (1a), or in the presence of an aromatic iodine compound (1b) and an oxidant (A) to fluorinate the alkene compound.
US12162851B2 Charged ion channel blockers and methods for use
The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof. The compounds, compositions, methods and kits of the invention are particularly useful for the treatment of itch and other dermal conditions.
US12162850B2 Formulations
There is provided an alkali metal salt of 4-chloro-N-[2-[(4-chlorophenyl)methyl]-3-oxo-1,2,4-thiadiazol-5-yl]benzamide and formulations thereof. This salt finds particular utility in the treatment or prevention of a disorder or condition ameliorated by the activation of AMPK.
US12162846B2 Drp-1 inhibitors as therapeutic agents
The subject invention provides compounds as Drp1 inhibitors, compositions comprising a Drp1 inhibitor, and methods for inhibiting Drp1 protein using the Drp1 inhibitors. Further provided are methods for treating and/or preventing a disease or condition associated with mitochondrial dysfunction, oxidative stress, inflammation and/or autophagy. Advantageously, the compounds and compositions of the subject invention can also be used to treat a variety of other conditions including, for example, autoimmune disorders, disorders of the nervous system, and cardiovascular disorders.
US12162843B2 High-purity thermostable crystal form of substituted 3-isoxazolidinone compound, preparation method therefor and application thereof
The application provides a high-purity thermostable crystal form of a substituted 3-isoxazolidinone compound, a preparation method therefor and an application thereof. The High-purity thermostable crystal form is prepared by a particular method of the present technology and is determined by single-crystal X-ray diffraction as an orthorhombic crystal, featuring a space group of P212121 and lattice parameters of a=9.2301(2) Å, b=11.0751(3) Å, c=12.7554(3) A, α=90°, β=90°, and γ=90°. The orthorhombic crystal can be conveniently applied in preparation of agrochemical formulations, such as a suspension concentrate and a water dispersible granule, and the new formulations prepared have a better herbicidal activity and crop safety.
US12162839B1 4,5-bis(4-bromophenyl)-2-(4-bromophenyl)-1-hexyl-1H-imidazole as an antimicrobial compound
An 4,5-bis(4-bromophenyl)-2-(4-bromophenyl)-1-hexyl-1H-imidazole compound, its synthesis, and its use as an antimicrobial agent.
US12162836B2 N-acyl-{4-[(4-aryl-phenyl)sulfonylmethyl]piperidine} compounds and their therapeutic use
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain N-acyl-{4-[(4-aryl-phenyl)sulfonylmethyl]piperidine} compounds of the following formula (collectively referred to herein as NASMP compounds) that are useful, for example, in the treatment of disorders (e.g., diseases) including, e.g., multiple myeloma, diffuse large B-cell lymphoma, acute myeloid leukemia, eosinophilic leukemia, glioblastoma, melanoma, ovarian cancer, chemotherapy resistant cancer, radiation resistant cancer, inflammatory arthritis, rheumatoid arthritis, psoriatic arthritis, psoriasis, ulcerative colitis, Crohn's disease, systemic lupus erythematosus (SLE), lupus nephritis, asthma, chronic obstructive pulmonary disease (COPD), Hidradenitis suppurativa, autoimmune hepatitis, etc. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, for example, in therapy.
US12162835B2 Crystalline psilacetin derivatives
The disclosure relates to crystalline psilacetin derivatives, compositions containing those crystalline derivatives, and methods of treatment using them. The crystalline psilacetin derivatives include crystalline 4-acetoxy-N-methyl-N-ethyltryptammonium (4-AcO-MET) hydrofumarate (“crystalline 4-AcO-MET hydrofumarate”), crystalline 4-acetoxy-N-methyl-N-allyltryptammonium (4-AcO-MALT) hydrofumarate (“crystalline 4-AcO-MALT hydrofumarate”), and crystalline 4-acetoxy-N,N-diallyltryptammonium (4-AcO-DALT) fumarate fumaric acid (“crystalline 4-AcO-DALT fumarate fumaric acid”).
US12162834B2 Reactive mesogens
Reactive mesogens (RMs), mixtures and formulations comprising RMs, polymers obtained from such RMs and RM mixtures, and the use of the RMs, RM mixtures and polymers in optical or electrooptical components or devices, like optical films for liquid crystal displays (LCDs).
US12162828B2 Process for preparing 3-hydroxy-3-methylbutyric acid (HMB) and salts thereof
The present invention pertains to a process for preparing 3-hydroxy-3-methylbutyric acid (HMB) or a salt thereof, the method comprising (a) reacting isobutylene oxide with cyanide in order to obtain 3-hydroxy-3-methylbutyronitrile, and (b) hydrolyzing the 3-hydroxy-3-methylbutyronitrile obtained in step (a) in order to obtain HMB, wherein hydrolysis step (b) is performed using either at least one nitrilase enzyme or, alternatively, using a combination of enzymes, said combination comprising at least one nitrile hydratase and at least one amidase.
US12162827B2 Isolation of chromoplastid carotenoids from fruits
The present invention relates to a method for the production of chromoplastid carotenoids that can be isolated from fruits. The procedure of the invention allows to selectively isolate, on the basis of the size (Size Exclusion Chromatography) and in pure form, the carotenoid in the form of regularly shaped and sized aggregates. The process includes the following steps: i) production, in suspension, of homogeneous fragments of the chromoplastidial membranes from the fruits; ii) solution isolation of the membrane components by solubilization with detergents; iii) selective and high-purity isolation of the carotenoid in the form of regular paracrystalline aggregates by a screening technique such as size exclusion chromatography (SEC—Size Exclusion Chromatography).
US12162826B2 Process for producing a renewable isoparaffin compound, renewable isoparaffin compound and use of the renewable isopraffin compound
The present invention refers to a process for producing a renewable isoparaffin compound with a high octane rating, comprising a step of Guerbet reaction between an initial C5 alcohol charge obtained from renewable raw material and methanol to produce a branched renewable C6 alcohol; dewatering of the branched renewable C6 alcohol into a C6 olefin; and hydrogenation of the C6 olefin into renewable isoparaffin. A renewable isoparaffin compound with a high octane rating, comprising at least 50% carbon of renewable natural origin in its composition, and use of said renewable paraffin in gasolines in general and in special high-performance gasolines, such as aviation gasoline, are also described.
US12162821B2 Treatment of cataplexy
The present invention relates to a method of treating cataplexy in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds.
US12162814B2 Dimerization and trimerization of C5 olefins via catalytic distillation
A process for the selective dimerization and etherification of isoolefins. The process including feeding a mixed C5 stream to a selective hydrogenation unit to convert dienes to olefins and isoolefins, producing a hydrogenated effluent stream. The hydrogenated effluent stream is fed to a first fixed bed reactor, producing a first reactor effluent. The first reactor effluent is fed to a catalytic distillation reactor system, producing a first overheads including unreacted olefins, isoolefins, oxygenate, and one or more C5 ethers and a first bottoms including dimers of the isoolefins, any produced trimers of the isoolefins, and heavy oxygenates. The first overheads is fed to a second fixed bed reactor, producing a second reactor effluent including dimers of the isoolefins, unreacted C5s, and unreacted oxygenates. The first bottoms stream and the second reactor effluent are combined and fed to a product splitter, producing a second overheads stream including unreacted C5 olefins, isoolefins, and oxygenates and a second bottoms stream including C10+ hydrocarbons.
US12162813B2 Process for preparing 3,3,3-trifluoroprop-1-ene
The present application provides a process of preparing 3,3,3-trifluoroprop-1-ene, comprising reacting 3-chloro-1,1,1-trifluoropropane with a base in an aqueous solvent component in the absence of a phase transfer catalyst.
US12162809B2 Fertilizer using carbon dioxide to increase plant yield and method of increasing plant yield
A fertilizer having a source of carbon dioxide, a source of nitrogen, and a source of carbohydrate, and an acid in an amount to provide increased retention of carbon dioxide in the soil. A method of enhancing the growth of plants by applying the fertilizer to soil containing the plant, the acid increasing retention of the carbon dioxide in the soil, and the plant exhibiting enhanced growth from the combination of the nitrogen, carbon dioxide and carbohydrate.
US12162808B2 Cooler for cooling clinker and method for operating a cooler for cooling clinker
A cooler for a cooling clinker of a cement production plant includes an aeration grate for conveying the clinker in a conveying direction, a ventilator for generating a cooling air flow that passes the aeration grate as a cross flow, and a measuring plane disposed above the aeration grate. The measuring plane includes a temperature measuring installation for ascertaining a temperature distribution in the measuring plane. The cooler includes an open-loop or closed-loop control installation to control a conveying rate of the clinker and/or a flow rate of the cooling air flow as a function of the ascertained temperature distribution. Further, a corresponding method can be utilized to operate a cooler for cooling clinker.
US12162807B2 Methods of surface functionalization of zirconia-toughened alumina with silicon nitride
Disclosed herein are methods for functionalizing the surface of a biomedical implant. The biomedical implant may be a zirconia-toughened alumina implant surface functionalized with silicon nitride powder for promoting osteogenesis.
US12162805B2 Porous honeycomb structure and method for manufacturing same
A porous honeycomb structure including cell channels passing through an interior of the porous honeycomb structure and partitioned by porous partition walls, wherein the porous partition walls include skeleton portions containing an aggregate and a bonding material, and pore portions formed among the skeleton portions and through which a fluid can flow; and the porous partition walls have a porosity of 40 to 48% as measured by a mercury intrusion method, and a cumulative 50% pore diameter (D50) from a large pore side of 6 to 10 μm in a volume-based cumulative distribution of pore diameters measured by the mercury intrusion method, and a maximum pore diameter observed with a scanning electron microscope of 40 μm or less, and a ratio of a contact area between the aggregate and the bonding material to a surface area of the bonding material observed with the scanning electron microscope of 61 to 80%.
US12162804B2 Sintering process for electrical feedthroughs
One aspect relates to a process for producing a sintered workpiece, which includes sintering of a ceramic material at a temperature of at least 1000° C. and in an atmosphere, in the case of which the partial pressure of atmospheric air is reduced to less than 10−6-times, based on the ambient air at the same temperature under equilibrium conditions.
US12162803B2 Foam modifiers for gypsum slurries, methods, and products
Disclosed is a foam modifier, e.g., useful for gypsum or cement slurries. The foam modifier comprises a fatty alcohol that is added to a gypsum or cement slurry that includes foaming agent, such as an alkyl sulfate surfactant. The fatty alcohol can be a C6-C16 fatty alcohol in some embodiments. The use of such a foam modifier can be used, for example, to stabilize the foam, reduce waste of foaming agent, improve void size control in the final product, and improve the gypsum board manufacturing process.
US12162801B2 Stress profiles of glass-based articles having improved drop performance
Glass-based articles comprise stress profiles providing improved drop performance. A glass-based substrate comprises: a glass transition temperature (Tg), a liquid fragility index (m), and fictive temperature (Tf), wherein Tg is less than or equal to 650° C., a value of Tf minus Tg is greater than or equal to −30° C., and m is greater than or equal to 25. A stress relaxation rate is greater than or equal to 10%, or 20% or more. The articles can comprise a lithium-based aluminosilicate composition and a fracture toughness that is greater than or equal to 0.75 MPa*m0.5. The stress profiles comprise: a spike region extending from the first surface to a knee; and a tail region extending from the knee to a center of the glass-based article, the tail region comprising: a negative curvature region wherein a second derivative of stress as a function of depth is negative; a depth of compression (DOC) that is greater than or equal to 0.22 t, and a parabolic region originating at the DOC and extending to the center of the glass-based article.
US12162797B2 Coating with thermal stability and anti-scratch properties, glass product having such coating, varnish product for producing such coating and method for protecting a glass surface and in particular a pharmaceutical primary glass container
The present invention describes a coating with lubricating and anti-scratch properties, comprising glycidoxypropyltrimethoxysilane and phenyltriethoxysilane. The present invention further describes a varnish product for producing such coating and a glass product, in particular a pharmaceutical primary glass container having such coating. Last, but not least, a method is disclosed for protecting a glass surface.
US12162795B2 Coating composition having high light transmittance, coating glass and method for preparation thereof, and cooking appliance using same
A cooking appliance includes a cooking chamber, a door that is configured to open and close the cooking chamber and has a door glass, a coating layer that is disposed at least one surface of the door glass and made of a coating composition. The coating composition includes 20 to 40 wt % of phosphorus pentoxide (P2O5), 15 to 30 wt % of aluminum oxide (Al2O3) and zirconium dioxide (ZrO2), 10 to 30 wt % of sodium oxide (Na2O) and potassium oxide (K2O), 10 to 25 wt % of boron trioxide (B2O3), and 10 to 15 wt % of zinc oxide (ZnO).
US12162794B2 Glass sheet with porous coating film and method of producing same
The coated glass sheet of the present invention includes: a glass sheet; and a coating film provided on at least one principal surface of the glass sheet and having a smooth surface. The coating film includes: isolated closed pores present within the coating film; and a matrix. The coating film is substantially free of open pores open at the surface of the coating film. For the coated glass sheet of the present invention, a transmittance gain is 2.5% or more, the transmittance gain being calculated by subtracting an average transmittance of the glass sheet as determined by applying light having wavelengths of 380 to 1100 nm to the glass sheet in the absence of the coating film on the surface of the glass sheet from an average transmittance of the coated glass sheet as determined by applying light having the wavelengths to the coated glass sheet from a side on which the coating film lies.
US12162792B2 Systems and methods for processing optical fiber
A system for processing an optical fiber includes: a draw furnace, the draw furnace containing an optical fiber preform; a bare optical fiber drawn from the optical fiber preform, the bare optical fiber extending from the draw furnace along a process pathway; and a slow cooling device operatively coupled to and downstream from the draw furnace, the slow cooling device exposing the bare optical fiber to a slow cooling device process temperature in the range from 1000° C. to 1400° C., wherein the bare optical fiber passes through the slow cooling device at least two times.
US12162791B2 Method for producing glass sheets and glass sheets produced by such method and use thereof
A method for producing ultra-thin glass sheets is provided that results in glass sheets with high edge strength. The method includes: hot forming a continuous glass ribbon with a glass thickness from molten glass; annealing the glass ribbon with an annealing rate chosen based on the glass thickness; producing a laser beam focus area that is longer than the glass thickness; introducing filamentary defects into the glass ribbon using the laser beam so that the filamentary defects extend from one face to the opposite face and are spaced apart from one another along the breaking lines to produce transverse breaking lines and longitudinal breaking lines with margins each comprising a thickened bead; separating the beads along the longitudinal breaking lines and separating glass sheets by severing along the transverse breaking lines.
US12162789B2 Methods and apparatus for forming laminated glass sheets
A forming body of a glass forming apparatus may include a first conduit comprising a first conduit wall and at least one slot in the first conduit wall, and a second conduit disposed above and vertically aligned with the first conduit, the second conduit comprising a second conduit wall and a slot extending through the second conduit wall. The forming body may include a first vertical wall and a second vertical wall extending between an outer surface of the second conduit wall and an outer surface of the first conduit wall at a first side and a second side, respectively, of the forming body. The forming body may include a first forming surface and a second forming surface extending from an outer surface of the first conduit wall and converging at a root of the forming body. Methods of forming a continuous laminate glass ribbon are also disclosed.
US12162787B2 Auger screen with adjustable length press zone
A dewatering device for removing entrained solids and debris from a liquid stream includes a housing defining a chamber. An auger has a first end positioned outside the chamber and a second end positioned inside the chamber. A compaction zone includes a first tube fixed to the housing. A second tube is slidably mounted on the first tube. A partition is secured to the second tube and has a first longitudinal position in the housing allowing a solids plug to form in the compaction zone and a second longitudinal position in the housing preventing the solids plug from forming in the compaction zone.
US12162785B2 Ozone distribution in a faucet
A faucet for dispensing a fluid includes a spout, a pull-out spray head removably coupled to the spout and including an outlet, and a valve assembly in fluid communication with the outlet. Additionally, the faucet includes a fluid treatment assembly configured to output a treatment into the fluid.
US12162783B2 Saline wastewater treatment method and system
A saline wastewater treatment method is provided. Raw water is pretreated to obtain pretreated raw water. The pretreated raw water is pressurized to a preset pressure, injected with zone, separated and filtered by a filtering device with a hollow fiber nanofiltration membrane or a hollow fiber reverse osmosis membrane inside to obtain a concentrate and a permeate. A pressure of the concentrate is controlled such that ozone in the concentrate is released to form micro-nano bubbles. The concentrate is partially injected into the pretreated raw water. A pressure of the permeate and a pressure of the raw water are respectively controlled such that ozone in the permeate and the raw water is released inside the filtering device to form micro-nano bubbles to flush the hollow fiber nanofiltration membrane or the hollow fiber reverse osmosis membrane. A saline wastewater treatment system is also provided.
US12162776B2 Method of producing magnesium hydroxide
The current invention relates to a process for producing magnesium hydroxide. Said magnesium hydroxide is suitable for mixing with polymers and for inducing flame retardant properties in polymeric compounds. According to aspects of the invention a magnesium oxide containing material is hydrated at high temperatures and pressures. The hydroxide containing material can be further dried and milled.
US12162775B2 Process for producing potassium sulphate
A process for the production of potassium sulphate by conversion of potassium chloride and sulphuric acid using a muffle furnace, said furnace comprising a reaction chamber and a combustion chamber, wherein in the reaction chamber potassium chloride (KCI) and potassium hydrogen sulfate (KHSO4) are reacted to form potassium sulphate while supplying heat to the reaction chamber from the combustion chamber, wherein the combustion chamber has at least a pair of regenerative burners and wherein the process comprises the steps of alternatingly causing one of the regenerative burners to perform a combustion operation in the combustion chamber to heat the reaction chamber and another of the regenerative burners to perform a heat-regenerating operation in a regenerator, wherein the pressure in the combustion chamber is kept at a pressure of between 0.2 and 3 mbarg.
US12162773B2 Extraction of lithium with chemical additives
Lithium is an essential element for high-energy rechargeable batteries and other technologies. Disclosed herein are systems and processes for the extraction of lithium from liquid resources. The aforementioned systems and processes utilize ion exchange materials that selectively and reversibly bind lithium. The performance of the ion exchange materials is enhanced by the use of a chemical additive.
US12162769B2 Silica particles and manufacturing method thereof
Silica particles have silica base particles, a structure that covers at least a part of a surface of the silica base particles and is configured with a reaction product of a trifunctional silane coupling agent, and a nitrogen element-containing compound, in which a content of the nitrogen element-containing compound with respect to the silica particles is 0.005% by mass or more and 0.50% by mass or less in terms of N atoms, and the silica particles have a degree of hydrophobicity of 10% or more and 60% or less and a volume resistivity of 1×108 Ω·cm or more and 1×1012.5 Ω·cm or less.
US12162768B2 Carbon matter-containing material production method, carbon matter-containing material, and soluble organic-inorganic composite
A method of producing a carbon material-containing material having a precisely controlled structure under a mild condition, a carbon material-containing material covalently bonded to an inorganic matter, and an intermediate material which is useful for, for example, industrially producing carbon-coated inorganic particles, hollow carbon fine particles, and can be industrially produced under a mild condition, are provided. The method of producing a carbon material-containing material includes heating a composition containing a compound (A), which causes a condensation reaction between the same and/or different molecules, and an inorganic matter. When the compound (A) has a condensation reaction temperature of T° C., a heating temperature is (T-150)° C. or more. The carbon material-containing material includes a carbon material and an inorganic matter. At least part of the carbon material and inorganic matter are covalently bonded. The organic-inorganic composite includes a carbon material and an inorganic matter. The carbon material is soluble in a solvent.
US12162766B1 Aerogel composite
An aerogel composite maintains an excellent level of heat insulation even when compressed and deformed. The aerogel composite can be included in batteries, electronic devices, automobiles, industrial equipment, structures, or the like, as a heat insulation material.
US12162763B2 Method for producing purified chlorosilanes
A method for producing purified chlorosilanes includes bringing crude chlorosilanes, such as crude trichlorosilane and crude silicon tetrachloride, which contain a boron compound and/or a phosphorus compound, into contact with chlorine (preferably 1 ppm mole to 3000 ppm mole with respect to 1 mole of crude chlorosilanes) in presence of alkylphenol such as 2-methylphenol, and then distilling the crude chlorosilanes.
US12162761B2 Silicon granules for the preparation of trichlorosilane and associated production method
A silicon granule, in particular, for the preparation of trichlorosilane, having a size of between 10 and 500 microns, and comprising: dopants in a weight fraction of less than 5 ppm; at least one co-catalyst selected from copper, iron, aluminum and calcium, in a weight fraction of between 1 and 2500 ppm; and metallic impurities, with exclusion of the at least one co-catalyst, in a weight fraction of less than 50 ppm.
US12162756B2 Process for hydrocarbon pyrolysis with a spatially separate heating zone and reaction zone inside the reactor space
A process can be utilized to produce hydrogen and pyrolysis carbon from hydrocarbons where the hydrocarbons are converted into hydrogen and carbon in a reactor at temperatures of 1000° C. or more and the reactor has at least two electrodes that are at a distance from one another in a flow direction of the hydrocarbons. To avoid carbon deposits in a region between the electrodes, which can lead to failure of a heating system, the carbon particles may be introduced into the reactor in countercurrent to the hydrocarbons and may be heated in a heating zone between the electrodes to a temperature above a decomposition temperature of the hydrocarbons at such a mass flow that a reaction zone in which the hydrocarbons are converted into hydrogen and carbon is spatially separated in a flow direction of the carbon particles from the heating zone.
US12162753B2 Preparation method for nano ferric phosphate with low sulfur content
A method for preparing nano iron phosphate with low sulfur content. The method may include: S1: mixing a phosphorus source and an iron source to obtain a raw material solution, then adding alkali and a surfactant, adjusting a pH, and stirring and reacting to obtain an iron phosphate dihydrate slurry, S2: adding phosphoric acid solution into the iron phosphate dihydrate slurry, adjusting the pH, heating and stirring for aging, and filtering to obtain iron phosphate dihydrate, S3: adding water into the iron phosphate dihydrate for slurrying, and grinding to obtain a ground slurry; and S4: adding the ground slurry into a washing solution to wash, carrying out solid-liquid separation, and calcining a solid phase to obtain the nano iron phosphate with low sulfur content.
US12162751B2 Free atom nanotube growth
In an embodiment, a method includes liberating feed atoms and forming at least one nanotube from the liberated feed atoms. Feed atoms disposed over a front side of a substrate are liberated in response to electromagnetic radiation that propagates from the back side of the substrate, through the substrate, to the front side of the substrate. And, from the liberated feed atoms, at least one nanotube is formed over the front side of the substrate in response to at least one catalyst separate from the substrate and disposed over the front side of the substrate and over the feed atoms.
US12162746B1 MEMS actuators having a physical gap filled with fluid
A MEMS micromirror device comprising, a reflective movable mirror, and a surrounding substrate coplanar to the mirror. A physical gap between the mirror and the surrounding substrate filled with fluid and finger structures extend from a perimeter of the movable mirror into the physical gap.
US12162744B2 Scalable modular system and method for storing, preserving,managing, and selectively dispensing beverages
An example system includes an incompressible, airtight pressurized container operable to maintain a pressure level in an internal pressurized environment, a transport system including at least two liquid transport conduits, and a mixing component, the two liquid conduits each being releasably coupled to a pressurized container interface coupled to the pressurized container and a dispensing interface, each liquid transport conduit including a controllable valve to enable or disable a flow of the liquid volume, the pressurized container interface capable of maintaining the pressure level, the mixing component being coupled to the at least two liquid transport conduits and the dispensing interface, a pressure regulation system connected to the pressurized container, the pressure regulation system operable to exert and maintain the pressure level within the pressurized container to enable compression of the first compressible liquid volume, and a control system operable to control the controllable valves and the pressure regulation system.
US12162741B2 Method and apparatus for realizing an aseptic connection between a valve unit and a tank container
Methods for realizing an aseptic connection between a valve unit and a tank container having an inliner are provided whereby, a disinfection unit which includes the valve unit is positioned around the spout of the tank container. The valve unit is then disinfected by exposing the valve unit to a disinfection fluid and/or to electromagnetic radiation while the valve of the valve unit is in an open position. After having closed the valve, an end portion of the valve unit is pressed against a closure element that blocks the spout of the inliner, to thereby establish fluid communication between the inner environment of the inliner and the interior of the valve unit. The disinfection unit is then removed and the valve unit is fastened to the tank container to ensure an aseptic connection between the valve unit and the tank container.
US12162740B2 Container sterilizing device, content filling system, container sterilizing method, and content filling method
A container sterilizing device includes a transport mechanism that transports a container and a supply unit that supplies a sterilizing agent to the container that is being transported by the transport mechanism. The supply unit includes a nozzle for spraying the sterilizing agent. The nozzle does not move in a vertical direction and, without being inserted into the container, moves in synchronization with the container that is being transported by the transport mechanism.
US12162733B2 Landing pad for a vehicle support
A landing pad that mounts to a foot of a vehicle support. The landing pad includes a bottom with an opening. A side wall extends upward from the bottom with the side wall positioned around a perimeter of the bottom. A top shelf extends radially inward towards the opening from the side wall with the top shelf extending over and being spaced away from the bottom. One or more slots extend from the top shelf to the opening. Each of the one or more slots includes a first section that extends into a lower surface of the top shelf and a second section that extends into a top surface of the bottom with the first section and the second section of each of the one or more slots being aligned to direct water to the opening.
US12162729B2 Construction elevator arrangement and a method for producing the same
A construction elevator arrangement and a method for producing the same includes a hoisting machinery, an electric cabinet, and cable drums positioned at the bottom of the shaft, an elevator car and a counterweight moving in the shaft, upper pulleys and rope suspenders fixed at an upper end of the lifting height of the construction elevator, and hoisting ropes being fixed to the rope suspenders during the operation of the construction elevator and gliding through the rope suspenders during an upwards jump of the construction elevator in the shaft. The hoisting ropes pass in a 2:1 roping between the car, the upper pulleys, the traction sheave, the counterweight, and the rope suspenders.
US12162728B2 Elevator rail
An elevator rail guides moving bodies of an elevator system. The moving bodies serve in particular as a car for the transport of people or goods or as a counterweight. The elevator rail has more than one guide contour including a guide contour 6 that interacts with a guide shoe such that in a first horizontal direction, a relative horizontal movement between the guide contour and the guide shoe is delimited at least on one side, and such that in a second horizontal direction, perpendicular to the first horizontal direction, a relative horizontal movement between guide contour and the guide shoe is delimited on both sides. The elevator rail has a hollow cross section bordered in a closed manner. The elevator rail has at least three of the guide contours that are formed on the outer surface of the elevator rail.
US12162726B2 Method and device for monitoring a passenger transport system using a detection device and a digital double
The disclosure relates to monitoring a state of a physical passenger transport system. A method comprises monitoring the state of the passenger transport system using an updated digital-double dataset (UDDD) that reproduces in a machine-processable manner characterizing properties of components of the physical passenger transport system in an actual configuration after its assembly and installation. At least one detection device is arranged in the conveyor belt of the physical passenger transport system that detects accelerations and changes in position in all three axes during operation, which are transmitted to the virtual conveyor belt of the UDDD. Using dynamic simulations, forces, impulses and vibrations resulting from the dynamic behavior of the conveyor belt, which act on the virtual components of the virtual conveyor belt, corresponding to the physical components, and on the virtual components which interact with the virtual conveyor belt, can be determined and evaluated.
US12162724B2 Systems and methods for displaying cabin operating panels in elevator cabs based on positions of passengers
An elevator system may include an elevator car that is configured to transport a passenger between floors of a building as well as a sensor system in the elevator car that is configured to detect a passenger's location, orientation, and/or height. The elevator system may further include a touchscreen that can display a virtual car operating panel at a location on the touchscreen that is based on the location, orientation, and/or height of the passenger. The virtual car operating panel may be configured to receive input from the passenger regarding a destination floor. The touchscreen may be configured to display a virtual car operating panel for each passenger based on each passenger's location, orientation, and/or height on the elevator car.
US12162722B2 Wireless early car arrival for mobile interfaces to elevator
A method of providing elevator data to a passenger including: receiving elevator data, the elevator data relating to an elevator car in an elevator system; wirelessly transmitting the elevator data to a mobile computing device; and conveying the elevator data to the passenger via a software application of the mobile computer device.
US12162720B1 Apparatus and method for spooling wire
A reel apparatus comprising a pipe; an outer flange assembly comprising two outer support walls connected to the pipe and wherein each outer support wall comprises an inner wall and an outer wall; an inner flange assembly comprising two inner support walls, wherein the inner flange assembly is rotated relative to the outer flange assembly and the pipe and wherein each inner support wall comprises an inner wall and an outer wall; and a motor assembly connected to the inner flange assembly and outer flange assembly, wherein the motor assembly is physically connect to the outer flange assembly and wherein the motor assembly is rotationally connected to the inner flange assembly.
US12162718B2 Hand system and hand
This hand system comprises: a suction pad that sucks a conductive workpiece by fluid effect; at least three electrodes that are arranged on the suction pad; and an electrical characteristics measuring device that measures the electrical characteristics of an electrical circuit formed by the contact between any two of the electrodes and the workpiece.
US12162717B2 Component supply device and method for operating component supply device
The component supply device includes a body, a first carrier tape transporter, a second carrier tape transporter, and a controller. The body includes a tape transport path. The first carrier tape transporter transports a carrier tape to a component pickup position. The second carrier tape transporter transports the carrier tape to the first carrier tape transporter. The controller is configured to communicate with the component installation device and control the first carrier tape transporter and the second carrier tape transporter in one operation mode selected from a plurality of operation modes.
US12162716B2 Dynamic tension control system for narrow fabric
A dynamic tension control system is described herein for driving linear material off a roll in a controlled manner. The dynamic tension control system may include a frame, a shaft for holding a roll of linear material, a motor for driving the shaft, and a dancer tensioning control system for controlling the motor. The dancer tensioning control system may include an actuator assembly through which the linear material passes and a proximity sensor for detecting whether the actuator assembly is proximate to the proximity sensor. When the linear material is pulled from the roll, tension is created in the linear material, which lifts the actuator assembly away from the proximity sensor. The dynamic tension control system may be configured to command, based on detecting that the actuator assembly is not proximate to the proximity sensor, the motor to drive the shaft to unwind linear material from the roll.
US12162715B2 Recording device
A printer includes a recording head, a belt, a scale unit, a reading head, a gripping unit. The belt includes a first surface configured to support a medium and a second surface opposite to the first surface. The gripping unit includes a first abutting portion that comes into contact with the first surface, and a second abutting portion that comes into contact with the second surface. The gripping unit can be changed between a gripping state of moving along with the glue belt while gripping the glue belt, and a release state of being separated from the glue belt. When the gripping unit is in the release state, the second abutting portion is separated from the second surface in conjunction with the first abutting portion being separated from the first surface.
US12162709B2 Image forming apparatus
A post-processing apparatus includes a first conveyor, a second conveyor, a third conveyor, and a conveyance passage corrector. The first conveyor conveys a sheet conveyed along a first conveyance passage downstream from the first conveyor. The second conveyor conveys the sheet along a second conveyance passage. The third conveyor conveys the sheet along a third conveyance passage. The conveyance passage corrector includes a retracting mechanism to retract from a joining position at which the third conveyance passage joins to the first conveyance passage and turns a conveyance direction of the sheet toward the first conveyor when the sheet enters from the third conveyance passage to the first conveyance passage.
US12162705B2 Power and control system for a loading dock assembly
A dock apparatus includes a plurality of loading dock components. An identification system is coupled with the plurality of loading dock components. A control panel is in signal communication with the plurality of loading dock components via the identification system. The identification system automatically cooperates with the control panel to define an operating sequence of the plurality of loading dock components. A power module is in signal communication with the control panel and an installed component of the plurality of loading dock components. The control panel provides instructions to the power module according to the operating sequence and the power module delivers a predetermined electrical current to the installed components of the plurality of loading dock components in a sequential pattern defined by the operating sequence.
US12162704B2 Automated product unloading, handling, and distribution
Disclosed is a robotic system including a telescoping transport conveyor with an automated unloader attached. The automated unloader includes a loading conveyor with at least two articulated robots attached to the first loading conveyor end. The automated unloader includes a control system with logic controlling the unloading of material to be handled from a transport container onto the telescoping transport conveyor, and thence to an automated palletizing system, where materials are loaded on pallets and supported by a pallet sleeve during storage or during transport to a stabilization system where pallet loads are stretch wrapped. Further disclosed are methods for controlling and operating the same to fully automate product unloading, handling, and distribution throughout a material handling facility.
US12162703B2 Combination ramp and load levelers
A ramp apparatus may include an extruded beam extending between a first ramp end and a second ramp end. The extruded beam may include a top wall, a bottom wall opposite the top wall, and a first side wall and a second side wall that each extend between the top and bottom walls. A first brace wall can extend at an angle away from the first side wall at a first interior corner of the extruded beam. A second brace wall may extend at an angle away from the second side wall at a second interior corner of the extruded beam.
US12162702B2 Transformable tray and tray system for receiving, transporting and unloading items
Features for loading, transporting and unloading of items are disclosed. Systems, devices and methods for such operations using a tray are described. In some embodiments, a tray having a moveable bottom allows for switching between a configuration for loading and unloading items in and out of the tray and a configuration for transportation of items inside the tray. The trays may also be stacked, for transportation of multiple trays at once, and nested, for saving space when storing the trays. In some embodiments, the trays may be used in conjunction with loading and unloading systems.
US12162696B2 Method for transferring coil springs from a coil winding device to a conveyor belt of a pocketed coil assembly machine
A mechanism for transferring coil springs from a coil winding device to a conveyor belt of a pocketed coil assembly machine comprises a magnetic lift platform for engaging a coil spring before being released at an output of the coil winding device. Further, the mechanism comprises a drive mechanism for moving the lift platform between the output of the coil winding device and the conveyor belt.
US12162694B2 Transport device with an ultrasonic generator and operating method
The transport device, which serves for the transport of pulverous or granular process material, includes an open or in itself closed transport frame made of metal for transporting process material, is held by a support device and is connected to an ultrasonic device having an ultrasonic generator, an ultrasonic transducer connected to the ultrasonic generator and a coupling rod connected to the ultrasonic transducer and having front and rear end pieces. A flat distributor body made of metal has upper, lower, rear sides and peripherally at least one connection side. The rear end piece of the coupling rod is connected to the ultrasonic transducer. The front end piece of the coupling rod is welded to the rear, upper, or lower side of the distributor body. The at least one connection side of the distributor body is integrally connected with or welded to the at least one transport frame.
US12162691B2 Modular conveyor mat and conveyor mat module therefor, as well as conveyor system
Modular conveyor mat (1), comprising a series of conveyor mat modules (2) successive in conveying direction, which conveyor mat modules are provided with a body part (5) extending transversely to a conveying direction, having a top (6) which bounds the body part at an upper side and a bottom (7) which bounds the body part at a lower side. The bottom is provided with a support surface (8) for supporting the body part on a plane guide (9). Successive conveyor mat modules are hingedly coupled with the aid of hinge pins (4) extending transversely to the conveying direction, reaching through hinge holes (16) in the coupling parts. At least a number of coupling parts are provided with a roller receiving space (13) having included therein a roller (19) which is bearing-mounted on the hinge pin, such that an outer surface of the roller is located wholly above the support surface and projects at least partly above the top of the body part. The body part is provided at the bottom thereof with a recess which, between mutually facing parts of the outer surfaces of successive rollers, leaves clear a space for therein receiving a tooth of a driving gearwheel.
US12162690B2 Rotatable retainer for hinge rods
A rotatable retainer for hinge rods in modular conveyor belts. The rod retainer includes a plug that is rotatably received in a socket in the edge portion of a conveyor belt module. An aperture through the plug is adjustable between a first locked and operational position guiding a hinge rod obliquely into a hinge-joint passageway between adjacent rows of belt modules and an unlocked second position guiding the hinge rod straight into the passageway. A sideguard, such as for a stacker belt, can optionally be formed with the plug.
US12162689B2 Apparatus to extend lift capacity of sidewall belt conveyor
A belt tension-reducing device is provided, which includes a support member; a pliable central wheel assembly configured to engage a both downwardly and upwardly moving portions of the conveyor belt; first and second outboard roller assemblies positioned to engage the downwardly and upwardly moving portions, respectively. A second effective rolling radius of the pliable central wheel assembly at a contact point with the upwardly moving portion of the conveyor belt can be greater than a first effective rolling radius of the pliable central wheel assembly at a contact point with the downwardly moving portion of the conveyor belt to reduce stresses on the belt in a vertical shaft. The belt tension-reducing devices can be arranged in a stacked configuration within the vertical shaft.
US12162686B2 Automated decant system
An automated decant system is disclosed for processing pallets of cased goods received at a facility, extracting packaging for the cases and transferring eaches within the cases to totes, possibly organized by SKU in sub-totes within the tote.
US12162683B2 Systems and methods for dispensing items
The present disclosure provides systems and methods for product handling and dispensing. In one aspect, the present disclosure provides a system comprising a tray comprising one or more lanes and one or more openings disposed on a bottom surface of the tray; one or more supports positioned within at least one of the one or more lanes, wherein the one or more supports are configured to support one or more items; and one or more dispensing units comprising one or more dispensing arms, wherein the one or more dispensing arms are configured to (i) couple to, engage with, or lift the one or more supports and (ii) transport (a) the one or more supports, (b) the one or more items on the one or more supports, or (c) both the one or more supports and the one or more items to one or more receiving areas or receiving units.
US12162681B2 Vehicle suspension system, conveyor system, and autonomous vehicles incorporating the same
A vehicle that includes a first rotatable frame that includes a first wheel assembly and a second wheel assembly. The vehicle also includes a second rotatable frame that includes a third wheel assembly and a fourth wheel assembly. The vehicle further includes a base frame configured to support a weight-bearing load. The vehicle further includes an axle member engaging the first rotatable frame, the second rotatable frame, and the base frame, wherein the first rotatable frame is rotatable about the axle member relative to the base frame and independent of the second rotatable frame, and the second rotatable frame is rotatable about the axle member relative to the base frame and independent of the first rotatable frame.
US12162679B2 Control system for a refuse vehicle
A refuse vehicle includes a chassis, an energy storage device, a body, a first electric power take-off system, and a second electric power take-off system. The energy storage device is supported by the chassis and is configured to provide electrical power to a prime mover. Activation of the prime mover selectively drives the refuse vehicle. The body is supported by the chassis. The first electric power take-off system is coupled to at least one of the body and the chassis, and includes a first motor that is configured to drive a first hydraulic pump to convert electrical power received from the energy storage device into hydraulic power. The second electric power take-off system is coupled to at least one of the body and the chassis, and includes a second motor that is configured to drive a second hydraulic pump to convert electrical power received from the energy storage device into hydraulic power.
US12162677B2 Bag dispenser
Disclosed is a bag dispenser that has a clam-shell arrangement including a hood, base, and also has a mounting system. A bag-dispensing mouth of the system has two opposing members that create resistance when bags (e.g., rolled bags) are pulled out through the mouth. The resistance is adjustable using a cam that can be locked in a variety of positions. The cam engages a drive bar to create the resistance.
US12162674B2 Container, device and method for storing or processing particulate materials to minimize or eliminate vibrations such as quaking or shaking
A container with lower vibrations, such as quaking and shaking as well as noise effects, known also as hooting, honking or howling, and an effective and cost-competitive method and device to decrease such phenomena during the discharge of granular material particles from silos, hoppers, bins, reactors and in general containers for storing or processing such granular material particles. The container includes at least one baffle that is attached to the container wall, in the lower portion or at the bottom of the tapered discharge part of said container, protruding towards the central axis of its tapered discharge part. The baffle forms a stagnant zone in the bed of the granular material particles in contact with the container wall whereby the particles in that zone flow under the friction against other particles instead of the friction between the particles and the wall.
US12162669B2 Collating system for conveyor belt rivets and method
A collating system for rivets is provided that includes a rivet holder for supporting rivets in a predetermined pattern. In one form, the rivet holder includes a body having cavities for supporting the rivets therein. The rivet holder body includes a top plate member and a bottom plate member. The rivet holder has drive heads connected to the top plate member via frangible portions and the bottom plate member has retaining webs disposed below the drive heads. The top and bottom plates are secured together to capture heads of the rivets between the drive heads and retaining webs. The drive heads may be driven downward to drive the rivet heads from the rivet holder and into bores of a guide block with the retaining webs flexing to release the rivet head from the lower bottom plate member. A method of using the rivet collating system is also disclosed.
US12162667B1 Beverage container
Implementations of beverage container may include an outer container, an inner container configured to removably couple within the outer container, a seal ring directly coupled to an inner perimeter of the outer container, the seal ring includes a plurality of openings wherein the plurality of openings are configured to fully close upon the inner container being fully inserted within the outer container. The seal ring is configured to lock the inner container within the outer container through a pressure differential.
US12162666B2 Closure for fluid-tight sealing of a vessel filled with a substance, container with a vessel and a closure as well as method for filling a container with a substance
The present invention relates in particular to a closure (3) for the fluid-tight closing of a vessel (2) filled with a substance (5), wherein the closure (3) is provided with a fluid-tight pressure-transmission element (9) and wherein the closure (3) is provided with a base body (8) to which the pressure-transmission element (9) can be attached in a fluid-tight manner, wherein the pressure-transmission element (9) is deflectable by pressurisation without incurring damage, for biological inactivation of microorganisms present in the substance (5), wherein the closure is configured in such a way that the pressure-transmission element (9), when the vessel (2) is closed with the closure (3), is held (clamped between the vessel (2) and the base body). The invention also relates to a corresponding container (1) and a corresponding method.
US12162665B2 Packaging for liquid products and a procedure for filling the packaging and a process for producing an inner bag for the packaging
Packaging for liquid food, where the packaging has an outer casing (2) of cardboard, an inner bag (8) of plastic foil which consists of e.g. completely recyclable bio-polyethylene plastic, where the inner bag is arranged inside the outer casing (2) and completely fills it when the inner bag is filled with the food, and an opening module, here called MF module (12), which contains an emptying device and a filling device arranged on a plastic disc (14), wherein the emptying device comprises an emptying channel (13) and a stopper (19) and where the filling device comprises a filling channel (25) and a filling plug (26) and wherein the MF module (12) is connected to the inner bag (8) by that the underside of the plastic disc (14) is welded to the outside of the inner bag so that the emptying channel (13) connected to a hole (11) in the inner bag (8) where the filling channel (25) opens into the emptying channel (13) is connected to the outer cover (2) in that top flaps (6a-6d) of the outer casing are attached to a slot (17) in the plastic disc (14) along the side edges thereof. The application also includes a method for filling the packaging and a method for producing an inner bag for the packaging.
US12162662B2 Product package, carrier, and blank therefor
Aspects of the disclosure relate to a package, a product carrier, and a blank for forming the product carrier. An aspect of the invention provides a package comprising a display card and an article disposed therein. The display card comprises a front panel and a rear panel. At least one first opening is provided in the front panel. A first portion of an article is received in the at least one first opening. At least one second opening is provided in the rear panel. A second portion of the article is received in the at least one second opening.
US12162660B1 Containment with internal seal and method for manufacture thereof
The present disclosure concerns a containment of pulp material that reduces reliance on adhesives and polymers. The containment is of two preformed semi-cylinders that linked together by using a preformed raised ridge that slots into a trough on the opposing half. The containment may optionally include a biopolymer based internal layer to provide a sealed containment. The present disclosure also concerns a cap for the containment with a narrowed wall and a recess to retain a lid liner with notched walls that allow for expansion at the closed end.
US12162657B2 Method of using a tamper-evident box
A method of using a box can include obtaining the box, the box comprising a box top and a box bottom, the box top comprising a first main panel and a first end panel, at least one of the first main panel and the first end panel defining a locking tab separable from the box top; the box bottom comprising a second main panel and a second end panel, the second end panel defining a locking opening, a lateral width of the locking tab at an ear thereof being greater than—and at a neck thereof being less than—a lateral width of the locking opening; inserting the locking tab into a gap defined at least in part by the second end panel, thereby hiding a portion of the locking tab behind the second end panel; and engaging the locking tab with the locking opening.
US12162652B2 Safety outer cap for a container
The present invention relates to an outer cap device for a container having a neck, the opening of which is closed off by a closure device comprising a region (13) to be safeguarded. According to the invention, this outer cap device comprises: —a main body (14) intended to be fastened to the neck of the container, this main body (14) comprising an upper wall (18) having an opening intended to be positioned next to this region (13) to be safeguarded when the main body (14) is fastened to the neck of this container so as to leave said region (13) to be safeguarded freely accessible, —a cover (16) comprising an internal face (22) and an inner skirt (23) extending from this internal face (22), the internal face (22) being closed in line with this inner skirt (23), this inner skirt (23) being designed to pass through the opening in the upper wall (18) of the main body (14) and surround the region (13) to be safeguarded when the cover (16) is in the closed position, —holding means for locking the cover (16) in the closed position and allowing it to be unlocked to pass into the open position, these holding means being configured to press the free end of the inner skirt (23) against the closure device in the closed position of the cover (16) so as to form a sealed barrier surrounding the region (13) to be safeguarded, in order to limit exchanges from this region (13) to be safeguarded with the single interior volume of the inner skirt (23).
US12162649B2 Containment and delivery systems for cryogenic storage
Various systems for the containment or delivery of a product are provided. The systems allow for the storage of products at low temperatures and include a container closure inserted into a container (10). The container closure may have an elastomeric body (12) and include a material (14) having a negative coefficient of thermal expansion. In other systems, the material having a negative coefficient of thermal expansion may be inserted between the elastomeric container closure and a seal. Other systems may include an insert at least partially embedded within the elastomeric body of a container closure, an actuator having a distal end movably attached to the insert, and a resilient element between the distal end of the actuator and the insert, wherein the resilient material expands radially upon displacing the distal end of the actuator toward the insert.
US12162648B2 Hidden flange child resistant closure for recloseable pouch and methods
A recloseable zipper pouch includes a recloseable zipper with interlocking profiles. At least one of the profiles has a grasping flange with a free end positionable both above and below the interlocking profile, and an attachment flange below the interlocking profile and attached to the wall of the pouch at an anchored portion on the attachment flange. The grasping flange is unattached to the first wall between opposite sidewall edges of the pouch. The complementary interlocking profile is attached to the opposite pouch wall. Some pouches can also include an opening in a side wall of the pouch to provide access to a portion of the grasping flange.
US12162642B1 Garbage bag opener device
A garbage bag opener device includes a pair of arms hingedly coupled together for inserting into a band opening in a neck of a garbage bag. The pair of arms is positionable in a deployed position to hold the garbage bag open for receiving garbage. A pair of pins is each attached to a respective one of the pair of arms and a latch is rotatably attached to a respective one of the pair of pins. The latch is positionable in a locked position to engage the other of the pair of pins when the arms are in the deployed position for retaining the pair of arms in the deployed position. The latch is positionable in an unlocked position to disengage the other of the pins to facilitate the pair of arms to be positioned in the stored position.
US12162635B2 Base stations including integrated systems for servicing UAVs
A base station is disclosed that is configured for use with a UAV. The base station includes: an enclosure with an outer housing that defines a roof section and an inner housing that is connected to the outer housing; one or more heating elements that are supported by the enclosure and which are configured to heat the roof section; one or more fiducials that are supported by the enclosure; an illumination system that is supported by the enclosure and which is configured to illuminate the one or more fiducials; and a visualization system that is supported by the enclosure.
US12162634B2 UAV docking station and UAV assembly
An unmanned aerial vehicle (UAV) assembly includes an UAV and an UAV docking station. The UAV docking station includes a housing, an extension piece, and a door. The housing is provided with an accommodation cavity and a hatch communicating with the accommodation cavity. The extension piece comprises an extension cavity and is connected to the housing. The extension piece is disposed on a side portion of a housing end which is near the hatch, and the extension cavity communicates with the accommodation cavity. The door is connected to the housing and disposed at the hatch, and the door is configured to open or close the hatch. A cross-sectional area where the extension cavity communicates with the accommodation cavity is greater than a cross-sectional area of the accommodation cavity. The UAV can be accommodated in the accommodation cavity of the UAV docking station.
US12162631B2 Passively damped end fittings and brackets
A passively damped mechanical system is disclosed, for example for use in aerospace applications where vibration can adversely affect navigational and operational instruments. In one example, the passively damped mechanical system includes an end fitting of a strut used to connect a structural element to a payload. The end fitting may include outer and inner cylindrical hubs, with a space between the outer and inner cylindrical hub at least partially filled with a viscoelastic material. In a further example, the passively damped mechanical system includes legs used to connect a structural element to a bracket configured to support a payload. Each leg may include a hollow interior having a lattice structure to add strength and a viscoelastic material to provide passive damping.
US12162628B2 Configurable sensing systems and methods for configuration
A sensor system can include a sensor configured to output raw sensor data, a plurality of processing modules configured to process the raw sensor data from the sensor to output processed sensor data, a state module for each processing module operative to cause a respective processing module to receive and/or process the sensor data, and a control module configured to receive a coded bitstring and activate or deactivate a predefined set of state modules based on the coded bitstring to control which processing modules process the sensor data and/or an order of processing. The coded bitstring can include a plurality of discrete bits less than the amount of processing modules and/or state modules. A plurality of the state modules and/or processing modules can be associated with at least one discrete bit of the plurality of discrete bits such that each coded bitstring corresponds to a predetermined group of state modules and/or processing modules.
US12162621B2 Fuel conditioning system and method configured to supply an aircraft turbine engine with fuel from a cryogenic tank
A fuel conditioning system configured to supply an aircraft turbine engine with fuel from a cryogenic tank. The fuel circuit comprising a buffer tank for supplying the turbine engine and a plurality of compression modules configured to supply the buffer tank, each compression module comprising an elementary tank of fixed volume, an elementary heat source configured to increase the temperature of the fuel in the elementary tank in an isochoric manner, an inlet valve connecting the elementary tank to an upstream part of the fuel circuit, an outlet valve connecting the elementary tank to the buffer tank, and a venting valve connecting the elementary tank to the cryogenic tank via a return circuit in which a gaseous stream circulates.
US12162620B2 Hybrid-electric aircraft, and methods, apparatus and systems for facilitating same
Hybrid-electric aircraft and a series hybrid powertrain configured to power the aircraft for a medium-haul flight. The series hybrid power train includes a plurality of energy storage units, at least one range extending generator, and a plurality of electric propulsors, each coupled to a distribution bus. The electric propulsors can produce a maximum thrust of at least 15 MW. During a cruise regime, the hybrid-electric aircraft can have an airspeed of at least 0.7 Mach at an altitude of less than 32000 feet, and the plurality of electric propulsors can have a fan pressure ratio of between 1.15 and 1.19. The hybrid-electric aircraft can have a degree of hybridization of at least 25% for the medium-haul flight and carbon dioxide equivalent (CO2e) well-to-wake greenhouse gas (GHG) emissions less than 0.25 lbs/Available Seat Mile (ASM).
US12162619B2 Powertrain system of an aircraft including cyrogenic cooling loop for superconducting electronics and method of operating the same
A powertrain system of an aircraft includes one or more electrical components to provide electrical power to one or more electrical loads of the aircraft. The system further includes a rechargeable cryogenic heat sink containing a volume of cryogenic cooling material. The cryogenic heat sink is configured to cool the one or more electrical components. A method of operating a powertrain system of an aircraft includes generating thermal energy at one or more electrical components of the powertrain system, fluidly connecting a cryogenic heat sink to the one or more electrical components, and cooling the one or more electrical components via a volume of cryogenic cooling material of the cryogenic heat sink.
US12162617B2 Battery charge difference calculation system
A power supply device includes a power generator, a drive source, a plurality of power supply lines, a plurality of batteries, a difference calculating unit 11, a difference summing unit 12, and an electric power summing unit 13. The difference calculating unit 11 is configured to calculate differences D1, D2, D3, and D4 between a target charge state set for each battery and an estimated charge state. The difference summing unit 12 is configured to sum the differences D1, D2, D3, and D4 calculated by the difference calculating unit 11. The electric power summing unit 13 is configured to sum the charge state calculated by the difference summing unit 12 and electric power used for the electric loads. A control unit 9 controls the drive source such that electric power calculated by the electric power summing unit 13 is generated by the power generator.
US12162614B2 Systems and methods for power distribution in electric aircraft
A electric aircraft power distribution system includes a first battery pack connected to at least a first load and to a common bus that connects the first battery pack in parallel to at least a second battery pack; a first electrical component electrically connected between the first battery pack and the first load and configured to disconnect the first load from the first battery pack in response to current above a first threshold current, wherein the first electrical component has a first disconnection time at the first threshold current; and a second electrical component electrically connected between the first battery pack and the common bus and configured to disconnect the first battery pack from the common bus in response to current above a second threshold current, wherein the second electrical component has a second disconnection time at the second threshold current that is higher than the first disconnection time.
US12162604B2 Seat pan mounted mobile device holder
A cabin attendant seat is disclosed. The seat may include a seat pan and a seatback. The seat may include a device holder coupled to the seat pan. The device holder may include a main body including a plurality of main body walls that define a main body cavity and a cover including a plurality of cover walls that define a cover cavity. The main body cavity and the cover cavity may form a device holder cavity configured to stow a mobile device. The device holder may include an opening configured to receive the mobile device. The device holder may include a device securing assembly configured to rotate between a first and second position, when in the first position the securing assembly configured to secure the mobile device within the cavity, when in the second position the mobile device configured to be removed from the device holder cavity.
US12162597B1 Directional tail thrust systems for rotorcraft
A directional tail thrust system for a helicopter includes a tailboom defining an internal air passage. The aft portion of the internal air passage includes an aft diffuser. The directional tail thrust system also includes a fan in fluid communication with the aft diffuser and a vane array including vanes coupled to the aft diffuser and configured to receive air from the fan via the aft diffuser. The vanes are pivotable to switch the vane array between various modes including an anti-torque mode to produce anti-torque thrust, a forward thrust mode to produce forward thrust and a pro-torque mode to produce pro-torque thrust.
US12162594B2 Chord lock assembly for a tiltrotor aircraft
Disclosed is a blade lock assembly, which may include a drag brace coupled to a fold crank assembly and to a rotary wing blade and may further include an actuator assembly configured to be coupled to a rotary wing cuff. The actuator assembly may include an actuator pin housing, an actuation pin at least partially sheathed by the actuator pin housing, and an actuator configured to extend and retract the actuation pin away from and toward the actuator pin housing.
US12162591B1 Anti-phase noise suppression rotor technologies
An anti-phase rotor system for an aircraft may include at least one rotor with at least two rotor blades. The aerodynamic profile of these two blades may be selected to create counteracting blade vortices to break up harmonic reinforcement due to the rotor blade passage. The aerodynamic profile may create a non-planar motion of one or more rotor blade passages, whereby the individual rotor blades are not co-planar during the rotation of said rotor. The rotor system may include a duct, which may include stationary vanes or struts configured in a manner so as to break up harmonic excitation to the rotor. The interior area of the duct at the area of the blade rotation may be designed in a manner so as to create a destructive rotor blade tip vortex interference.
US12162589B2 Coupled landing gear and methods of use
A coupled landing gear apparatus for an aircraft including at least a nose gear disposed forward of a neutral point of an aircraft by a first distance and at least a main gear disposed aft of the neutral point of the aircraft by a second distance. The at least a nose gear and the at least a main gear are in communication with one another.
US12162587B2 Aircraft rudder pedal with mechanical kinematic chain
An aircraft rudder pedal includes a frame, a pair of pedals, an output shaft and a mechanical kinematic chain for transmitting to the output shaft a displacement of at least one of the pedals relative to the frame. The mechanical kinematic chain comprises a central transmission part able to be rotated relative to the frame by a displacement of one of the pedals relative to the frame. The mechanical kinematic chain also includes a transmission mechanism joining the central transmission part to the output shaft. The transmission mechanism includes a homokinetic association of two universal joints between said central transmission part and the output shaft.
US12162585B2 Passive rotor pitch control system
One example includes a passive rotor pitch control system. The system includes a counterweights that are each associated with one of a respective plurality of rotors and can be arranged to have a center of mass configured to provide a pitch torque about a pitch axis associated with the respective one of the rotors in response to rotation of the rotors about a rotation axis. The system also includes a spring forcer comprising a pitch rod and a spring configured to provide a spring force on the pitch rod. The system further includes a pitch change assembly coupled to the counterweights and the pitch rod. The pitch change assembly can be configured to rotate a pitch of each of the rotors from a first pitch state to a second pitch state in response to a sum of pitch torques associated with the counterweights being greater than the spring force.
US12162575B2 Energy efficient underwater inflatable array using hydrofoam and water swelling material
Underwater Deployable Structures (UDSs) capable of achieving inflation via mechanical pumps, moisture-activated expanding foams, water swelling material, or a hybrid of a mechanical pump and water swelling material. Moisture expanding foams begin as polyurethane-based resins of low viscosity, and react in the presence of water to become solid foam. In their final forms, the foams exist as open- or closed-cell, and vary in strength, elasticity, and rigidity. Water swelling material is also disclosed wherein the water swelling material is capable of achieving expansion numerous (e.g., up to about 250) times its initial volume when in contact with water and can shrink back to its initial volume upon dehydration, making the UDSs reusable. A mechanical pump may optionally be used to assist in initial inflation until the water swelling material reaches full expansion.
US12162573B1 Throwing protection apparatus for adaptive navigation situation awareness device based on ship pilotage
A throwing protection apparatus for an adaptive navigation situation awareness device based on ship pilotage comprises: a connecting apparatus, a landing buffer apparatus, a fixing apparatus, a pressing apparatus, a shell and a control apparatus; wherein a bottom of the shell is provided with an opening for the adaptive navigation situation awareness device to pass through; one end of the connecting apparatus is fixedly connected to an unmanned aerial vehicle, and the other end of the connecting apparatus is slidably connected to the shell; the adaptive navigation situation awareness device is arranged in the shell and is fixed by the fixing apparatus arranged on the shell; the pressing apparatus is mounted on the shell and is positioned above the adaptive navigation situation awareness device; the landing buffer apparatus is mounted outside the shell; and an air bag and a distance measuring sensor are fixedly mounted on the shell.
US12162572B2 Apparatus for cleaning or maintaining the outer side of a hull or the inner side of a cargo hold of a marine vessel with improved attachment capacity
An apparatus for cleaning or maintaining the outer side of a hull of a marine vessel or the inner side of a cargo hold of a marine vessel. The apparatus includes a housing provided with a first row of magnetic driving and attachment elements and a second row of magnetic driving and attachment elements. The first and second row being parallel and arranged at opposing lateral sides of the housing. The first row of magnetic driving and attachment elements comprising magnetic wheels and/or a continuous track with magnetic links. The second row of magnetic driving and attachment elements comprising magnetic wheels and/or a continuous track with magnetic links. Further, the apparatus is provided with least one suspended magnetic wheel arranged between the first row and the second row, the at least one suspended magnetic wheel being resiliently suspended from the housing and biased towards the housing.
US12162571B2 Boat and structural reinforcement therefor
A support for inclusion internally within a plastic boat body to structurally reinforce the plastic boat body is provided. The support may comprise a support plate and a support brace. Also provided is a reinforced component for a plastic boat body, comprising an interior support; and one or more plastic exterior walls. Plastic boats comprising supports and reinforced components are also provided. Further provided are associated kits, systems, and methods.
US12162561B2 Cargo-carrying wheeled vehicle
A cargo-carrying wheeled vehicle, said vehicle comprising: at least a cargo hold chassis (10); at least a rider support chassis (20) configured to be operatively behind said cargo hold chassis (10), in that, said cargo hold chassis (10) and said rider support chassis (20) cooperate to maintain centre of gravity of said vehicle, after addition of cargo to said cargo hold chassis (10) and after addition of rider to said rider support chassis (20), to obtain a naturally balanced position for said vehicle in a loaded as well as an unloaded condition.
US12162560B2 Three-wheel motor vehicle and control system
A three-wheeled vehicle having a front wheel assembly attached to a chassis. The chassis includes a rotational control shaft having a rotational axis that is generally directed in a longitudinal direction of the vehicle. The rotational control shaft is integrated with or secured to the chassis in a non-rotational manner and passes through the front wheel assembly in a rotationally-free manner, such that the rotational control shaft can rotate about its rotational axis. The front wheel assembly includes one or more lean control motors, which are operably configured to rotate the rotational control shaft about its rotational axis thereby causing the chassis to lean from side to side to improve the handling ability of the vehicle. Some embodiments include a lean control system configured to automatically control the degree of rotation of the chassis.
US12162551B1 Bicycle with security features
The bicycle with security features includes a frame, a cable lock, a pedal lock, a motion alarm, a GPS tracker, a solar cell array, a smart phone interface, a battery, and a battery charger. The frame may house anti-theft and rider safety features. The cable lock and the pedal lock may prevent a bicycle from being moved by thieves. The motion alarm may produce an alert if the bicycle is disturbed. The GPS tracker may determine and report the location of the bicycle. The anti-theft and rider safety features may be controlled from a smart phone.
US12162550B2 Vibration damper system for a steering wheel arrangement of a motor vehicle
It is provided a vibration damper system for a steering wheel arrangement of a motor vehicle, which is provided for arrangement on a steering wheel element of the steering wheel arrangement. The vibration damper system comprises a vibration damping mass for damping the vibration of the steering wheel arrangement, an elastic bearing element which comprises a fastening element for fastening the elastic bearing element to one of bearing element and vibration damping mass, and a fastening means for fastening to the other of steering wheel element and vibration damping mass, wherein the elastic bearing element sectionally rests against the fastening means.
US12162545B2 Pivot assembly for a ground-contacting wheel assembly
A pivot assembly for connecting a ground-contacting wheel assembly to a frame member of a track system assembly has a base defining a first interlocking member, a resilient body structured for being received at least partially within the base and having a second interlocking member connectable to the first interlocking member, and an axle assembly configured for rotatably connecting the ground-contacting wheel assembly to the frame member, the axle assembly including a third interlocking member connectable to the second interlocking member. The resilient body is at least partially wrappable around the peripheral surface of the axle assembly. Upon deformation of the resilient body, the axle assembly is pivotally movable relative to the frame member of the track system assembly about at least one of a longitudinal axis and a vertical axis.
US12162543B2 Steering control device
A first circuit energizes a steering assist actuator to electrically assist steering of a driver. A second circuit is provided in a same housing as the first circuit and energizes a positional actuator to move a steering position. A controller operates the first and second circuits to control operations of the steering assist actuator and the positional actuator. The controller changes a priority between the first circuit and the second circuit in a start period, in which the steering control device is started, a normal operation period, in which the steering control device is operated normally, and a stop period, in which the steering control device is stopped. The priority includes at least one of an order of operating the first circuit and the second circuit, output allocation between the first circuit and the second circuit, and output magnitude between the first circuit and the second circuit.
US12162541B2 Motor assembly and steering apparatus for vehicle having the same
According to embodiments of the present disclosure, it is possible to easily adjust the tension of the belt, and simplify the motor installation structure in the steering system, and share a motor between vehicle types.
US12162540B2 Handwheel actuator modular interface
A handwheel actuator for a steer by wire system may include a compressive loading assembly, a feedback actuator and a column for operably coupling a handwheel to the handwheel actuator. The column may operably couple a handwheel to the handwheel actuator. The column may include a column shaft extending from a first end of the column to a second end of the column. The feedback actuator may be operably coupled to the second end of the column. The feedback actuator may provide tactile feedback to an operator responsive to movement of the handwheel. The feedback actuator may include a torsion bar substantially coaxial with the column shaft. The compressive loading assembly may be disposed at the second end of the column to operably couple the column shaft and the torsion bar under a compressive load when the column is joined to the feedback actuator.
US12162539B2 Aerodynamic skirt securing connector comprising a stabilizer
A strut member to be secured to the floor structure includes a top skirt-contacting portion for the aerodynamic skirt panel to be secured thereto, a lower skirt-contacting portion for the aerodynamic skirt panel to be secured thereto distant from the top skirt-contact portion, and a strut portion connecting the top skirt-contact portion to the lower skirt-contacting portion. The strut member provides a clearance in which the skirt panel is free of contact with the strut member between the top skirt-contact portion and the lower skirt-contacting portion. The strut portion is configured to resiliently buckle between a buckled position upon the skirt panel undergoing a force exceeding a threshold value toward the strut member and an original position when no force is applied and when the skirt panel is undergoing a force that is less than the threshold value.
US12162535B2 Apparatus for measuring steering angle
An apparatus for measuring the steering angle of a wheel assembly including a suspended wheel mount and at least one suspension arm, the apparatus including a reference bracket, a rotating bracket and an angle sensor, the reference bracket and the rotating bracket each respectively including a measurement end and a mounting end, wherein the measurement ends of the reference and rotating brackets are rotatably coupled about a rotation coupling point such that the brackets can rotate with respect to one another, wherein the mounting end of the rotating bracket is coupled with the suspended wheel mount and the mounting end of the reference bracket is coupled with the suspension arm, and wherein the mounting end of the reference bracket is positioned on a plane defined by a steering axis of the suspend-wheel mount and a rotation axis between the suspension arm and the suspended wheel mount.
US12162531B1 Vehicle steering device
A vehicle steering device comprises an upper tube having a steering shaft rotatably coupled to an inside thereof, a lower column having the upper tube inserted thereinto and having a recess formed in an outer surface of distance portions disposed to face each other with a cut hole axially formed in an outer circumference disposed therebetween, a mounting bracket coupled to respective outer surfaces of the distance portions and having tilt slots formed in two opposite sides thereof, a fixed gear member provided on an outer surface of one side of the mounting bracket and having a communication hole communicating with the tilt slot, and a movable gear member movably coupled to the fixed gear member and positioned in the recess through the communication hole and the tilt slot.
US12162528B2 Stroller
A collapsible stroller comprising a handle assembly, a front leg assembly and a rear leg assembly pivotably connected to one another such that the stroller is able to be moved between a folded configuration, where the front leg and handle assemblies are folded to positions substantially adjacent to the rear leg assembly, and an unfolded configuration, where the front leg and handle assemblies are unfolded to positions away from the rear leg assembly, and a link assembly comprising a front member and a rear member pivotally connected to one another, wherein the front member is pivotally connected to an intermediate portion of the front leg assembly and the rear member is pivotally connected to an intermediate portion of the rear leg assembly, such that when the stroller is moved to its folded configuration the front and rear members are folded toward each other to lie substantially adjacent to one another and the front and rear leg assemblies, and when the stroller is moved to its unfolded configuration the front and rear members are folded away from each other and the front and rear leg assemblies such that they are substantially coplanar with one another, and wherein the link assembly further comprises a biasing means for biasing the front and rear link members toward their unfolded positions.
US12162526B2 Train operation control method and apparatus, and non-transitory computer-readable storage medium
A train operation control method includes acquiring a battery state of an arriving train, and determining a target dwell time of the arriving train according to the battery state of the arriving train, actual operation data of the arriving train, and planned operation data of the arriving train, so that the arriving train stops for charging according to the target dwell time. The actual operation data of the arriving train includes an actual arrival time of the arriving train, and the planned operation data of the arriving train includes a planned arrival time, a planned dwell time, a minimum dwell time, and a maximum dwell time of the arriving train.
US12162525B2 Method and system for regulating guided vehicle headways
A method and system for managing traffic of guided vehicles over a railway network include a first ATS system for regulating traffic of guided vehicles over a first regulation domain of the network and a second ATS system configured for regulating traffic of guided vehicles over a second regulation domain. The regulation domains have a common boundary and at least one track connects a first position within the first regulation domain to a second position within the second regulation domain. The second ATS system detects limited traffic capacity at the second position and automatically computes, as a function of the detected limited traffic capacity, a target headway between two successive guided vehicles crossing the common boundary for entering the second regulation domain. The first ATS system automatically determines, from the received target headway, a reference timetable, complying with the received target headway, for the first regulation domain.
US12162521B2 Cushioning unit with reduced tail yoke
A cushioning apparatus for a railway car employs a shortened yoke with a reduced-width tail for placement between stops in a conventional railway car sill. A first stack of rigid plates with elastomeric pads is provided between the straps of the modified yoke behind the coupler follower, and a second stack of plates and elastomeric pads is positioned in the sill behind the modified yoke to absorb buff loads on the coupler. In embodiments, the entire assembly may be placed in a sill having forward stops, intermediate stops, and rear stops, adapted to house a hydraulic cushioning unit.
US12162516B2 Determining transport operation level for gesture control
An example operation includes one or more of detecting a gesture in a transport, responsive to the gesture being detected, identifying an action to be performed by the transport, identifying currently engaged transport operations, determining whether performing the action will exceed a threshold transport operation level based on the currently engaged transport operations, and determining whether to perform or cancel the action corresponding to the detected gesture based on whether the threshold transport operation level will be exceeded.
US12162511B2 Vehicle control device and electronic control system
There are realized a vehicle control device and an electronic control system with high reliability capable of safely shifting control even when an operation abnormality occurs in a sensor around a vehicle or an arithmetic block that processes sensor fusion. The vehicle control device includes a first arithmetic block which performs sensor fusion processing based on pieces of raw data output from a plurality of surrounding environment sensors, a second arithmetic block which performs sensor fusion processing based on pieces of object data generated by processing the pieces of raw data output from the plurality of surrounding environment sensors, and a third arithmetic block which diagnoses an output result of the first arithmetic block by using the output result of the first arithmetic block and an output result of the second arithmetic block.
US12162500B1 Vehicle representation determination
Techniques for accurately predicting vehicle state errors for avoiding collisions with objects detected in an environment of a vehicle are discussed herein. A vehicle safety system can implement a model determine a representation of the vehicle usable in a scenario. The model may dynamically determine a size and/or a heading of the vehicle representation based on differences between a candidate trajectory and a current trajectory of the vehicle. The safety system can identify a potential collision between the vehicle and the object based at least in part on an overlap of the vehicle representation and an object representation.
US12162499B2 Method and device for predictive vehicle control
The present invention relates to a device having at least one computing unit, which is configured to ascertain a specified target power profile curve (213) for a vehicle, to determine a tolerance band (211) for the target power profile curve (213), wherein the tolerance band (211) is limited by an upper limit line (215) and a lower limit line (217), to determine an expectation characteristic curve (219) for a power of the vehicle to be expected in the future by extrapolating a power development of the vehicle at a current setting of the vehicle for a specified temporal prediction window (229), and to enable a control command (315, 319) to be provided by the driver model in order to modify the setting of the vehicle in the event that the expectation characteristic curve (219) intersects at least one of the upper limit line (215) and the lower limit line (217) of the tolerance band (211) within the temporal prediction window (229).
US12162496B2 Driving support device
A driving support device is provided which can estimate the line-of-sight of an occupant with high accuracy. A driving support device 11 includes: a peripheral information acquisition unit 40 which acquires peripheral information of the periphery of a vehicle 1; a driver monitor camera 50 which acquires occupant information related to the occupant of the vehicle 1; an outside-world information detection unit 201 which detects the outside-world information including the position and speed of the target in the surroundings of the vehicle 1 based on the peripheral information; a line-of-sight estimation unit 202 which estimates the line-of-sight of the occupant of the vehicle 1 based on the occupant information; and a line-of-sight correction unit 203 which corrects the estimated line-of-sight, based on the outside-world information detected by the outside-world information detection unit 201.
US12162493B2 Merge assistance device and merge assistance method
A merge assistance device of the present disclosure includes: an own-vehicle position acquisition unit for acquiring an own-vehicle position; a provisional merge point setting unit for setting a provisional merge point on an own lane; a lane-to-lane distance calculation unit for calculating a lane-to-lane distance from the own lane to the target lane; an attention point setting unit for setting a frontward attention point and a rearward attention point on the own lane; a first approximation expression deriving unit for deriving a first approximation expression approximating frontward attention points and rearward attention points; a second approximation expression deriving unit for deriving a second approximation expression approximating the target lane; and a merging-possible area start point estimation unit for estimating a merging-possible area start point on the target lane on the basis of an own-lane width, a target-lane width, and the first and second approximation expressions.
US12162484B2 Lane following system and method considering driving assistance lane
The present invention provides a lane following system and method considering a driving assistance lane that can flexibly cope with complex roadway situations and enable lane following to improve the reliability of an LCA system, and furthermore, expand a range of a road to which an autonomous driving system is applied.
US12162482B2 Always on lateral advanced driver-assistance system
A method includes, in response to an ignition on signal: determining, using one or more sensors, whether a host vehicle is moving from a first lane to a second lane; determining, using one or more sensors, whether an object is in at least one of a blind zone of the host vehicle and in the second lane within a threshold distance of the host vehicle; in response to a determination that an object is in at least one of the blind zone of the host vehicle and in the second lane within the threshold distance of the host vehicle, performing at least one operator assistance maneuver; and, in response to a determination that an object is not in at least one of the blind zone of the host vehicle and in the second lane within the threshold distance of the vehicle, not performing the at least one operator assistance maneuver.
US12162475B2 Automotive auxiliary LADAR sensor
A vehicle and ladar sensor assembly system is proposed which makes use of forward mounted long range ladar sensors and short range ladar sensors mounted in auxiliary lamps to identify obstacles and to identify potential collisions with the vehicle. A low cost assembly is developed which can be easily mounted within a body panel cutout of a vehicle, and which connects to the vehicle electrical and computer systems through the vehicle wiring harness. The vehicle has a digital processor which interprets 3D data received from the ladar sensor assembly, and which is in control of the vehicle subsystems for steering, braking, acceleration, and suspension. The digital processor onboard the vehicle makes use of the 3D data and the vehicle control subsystems to avoid collisions and steer a best path.
US12162472B1 Real-time control method for additional yaw moment of distributed drive electric vehicle
The present disclosure relates to a real-time control method for an additional yaw moment of a distributed drive electric vehicle, including the following steps: acquiring and inputting a real-time motion state of the distributed drive electric vehicle into a vehicle dynamics model, using a yaw rate and a sideslip angle of the distributed drive electric vehicle as tracking targets to suppress actuation energy, and performing optimization calculation on an additional yaw moment to acquire an amount of the additional yaw moment distributed for each tire; and in the optimization calculation process, a linear expression of the sideslip angle with respect to the additional yaw moment and a linear expression of the yaw rate with respect to the additional yaw moment are constructed, so as to perform search calculation on the additional yaw moment.
US12162471B2 Neural-network based MTPA, flux-weakening and MTPV for IPM motor control and drives
A method for determining MTPA, flux-weakening, and MTPV operating points over the full speed range of an IPM motor for the most efficient torque control of the motor using a neural network is provided. The neural network is trained using a cloud-based neural network training algorithm. A special technique is developed to generate neural network training data, that is particularly suitable and favorable, to develop a high-performance neural network-based IPM torque control system, and the impact of variable motor parameters is embedded into the neural network system development and training. The provided method can achieve a fast and accurate current reference generation with a simple neural network structure, for optimal torque control of an IPM motor. The method can handle the MTPA, MTPV, and flux-weakening operation considering physical motor constraints.
US12162469B2 Controller, method, and computer program for controlling transmission
A transmission controller includes a processor configured to set acceleration/deceleration start timing at which a vehicle starts accelerating or decelerating, based on at least one of a sensor signal representing the situation around the vehicle, the current position of the vehicle, a map including information on a road being traveled by the vehicle, and operation of the vehicle by a driver, downshift a second transmission of a power train including two motors and an engine before the acceleration/deceleration start timing, and control the power train to vary first and second gear ratios of a first transmission so as to keep the RPM of the engine constant. The first transmission is capable of steplessly varying the first and second gear ratios, which are gear ratios between one of the motors and the engine and between the other motor and the engine, respectively.
US12162467B2 Control apparatus
A control apparatus is configured to control a vehicle. The vehicle includes an engine, a generator, and a drive motor. The generator is configured to generate electric power by using motive power to be outputted from the engine. The drive motor is coupled to a drive wheel. The engine, the generator, and the drive motor are coupled to each other via a planetary gear mechanism. The control apparatus includes a processor configured to control an operating point of the engine by controlling respective operations of the generator and the drive motor. The processor is configured to change a fuel consumption characteristic of the engine on the basis of traveling characteristic data, and to control the operating point of the engine on the basis of the fuel consumption characteristic. The traveling characteristic data indicates a traveling characteristic in the past of the vehicle driven by a driver of the vehicle.
US12162464B2 Redundant brake and brake failover for autonomous vehicles
Techniques are described for determining failover to a redundant braking system. An example method can include a system determining a fault occurring in a braking system of an autonomous vehicle (AV) operating in an autonomous mode, the braking system comprising a first braking system and a second braking system, the fault occurring in at least one of the first braking system and the second braking system, and the AV using the first braking system. The system can further determine whether to switch from using the first braking system based at least in part on determining the fault. The system can further transmit to an alert system of the AV, a request to generate an alert for manual control of the AV based at least in part on determining the fault. The system can further deactivate the autonomous mode of the AV based at least in part on determining the fault.
US12162460B2 Method for controlling brake fluid pressure using ESC system
A method for controlling a brake fluid pressure using an ESC system in a vehicle is to reduce the braking distance and increase braking safety of a vehicle on a wet road surface by performing brake fluid pressure control based on precipitation data.
US12162454B2 Aircraft brake wear optimization
A method for aircraft brake wear optimization includes processes by which the actual instantaneous temperature of brakes can be determined during taxi braking operations. The invention is particularly applicable to carbon disc brakes in aircraft. In the system, the energy absorbed by the carbon disc brakes during taxiing operation is calculated and a conversion made from energy absorbed to disc temperature is made. The system uses less than a full complement of brakes during taxiing such that the brakes actually employed during taxiing are at elevated temperatures, which are characterized by improved brake wear. The system provides substantially instantaneous thermal information, in contrast to the prior art relying upon thermal measurements rather than energy calculations.
US12162450B2 Actuator for parking brake
Disclosed is an actuator for a parking brake. In accordance with an aspect of the disclosure an actuator for a parking brake includes a motor generating power; a reduction gear portion configured to transmit the power of the motor to a parking portion implementing a parking braking of a vehicle; a housing in which the motor and the reduction gear portion are accommodated; a housing cover for closing the housing; and a locking portion configured to limit rotation of the reduction gear portion; wherein the locking portion is configured to a locking member that is provided to be movable in an axial direction of the reduction gear portion and is close contact with or spaced apart from the reduction gear portion, an elastic member elastically supporting the locking member toward the reduction gear portion, an electromagnet member configured to separate the locking member from the reduction gear portion by generating an electromagnetic force when the power is applied.
US12162449B2 Electromechanical brake pressure generator including spindle drive unit, braking system
An electromechanical brake pressure generator including a spindle drive unit for converting a rotational motion of an electric motor-driven drive shaft into a translatory motion of a piston that is coupled to the spindle drive unit, the spindle drive unit being operatively connected to the drive shaft via a multi-stage transmission. The multi-stage transmission is a planetary gear set having a first and a second stage. With the aid of the transmission, a spindle or a spindle nut of the spindle drive unit is drivable, which is rotatably mounted in a housing of the brake pressure generator via a bearing assembly receiving axial and radial forces. A braking system for a vehicle including an electromechanical brake pressure generator is also described.
US12162448B2 Brake control device
A brake control device includes a control unit configured to calculate a target current value, which is a target current value to the motor, based on master cylinder hydraulic pressure, and reduce an energization level to the motor when an actual current value, which is an actual current value to the motor, reaches the target current value, set a hydraulic pressure threshold value, which is a threshold value of the master cylinder hydraulic pressure corresponding to a braking force necessary for the vehicle to stop based on an inclination angle of a road on which the vehicle is stopped, and calculate a time change amount of the master cylinder hydraulic pressure, and in a case where the time change amount exceeds a predetermined change amount, increase an energization level to the motor when the master cylinder hydraulic pressure subsequently becomes less than or equal to the hydraulic pressure threshold value.
US12162444B2 Actuating device for a mechanical brake system
An actuating device may include an energy recovery unit for a mechanical brake system. The actuating device may have an actuating drive for a brake application movement of a brake part for a service brake function. The actuating device has a force cartridge with a prestressed spring and with a ramp bearing as the energy recovery unit The ramp bearing may be fastened to the actuating drive on one side and to the spring on the other side. The force cartridge is fitted on a line of force action of the actuating drive and interacts with the actuating drive such that a force component for assisting the actuating drive is provided in a manner dependent on an adjustment position of the actuating drive.
US12162438B2 Support device
The invention relates to a support device for securing a load to a vehicle, comprising guiding means, pivoting means and a support platform. The pivoting means are connected to the support platform such that the support platform can be pivoted about a vertical axis of the pivoting means.
US12162435B1 Vehicle mounted shoe cleaner
A vehicle mountable shoe cleaner includes a brush plate with a plurality of bristles on the top side and pads on the bottom side. Additionally, a second plate secures to the brush plate such that a vehicle step is clamped between brush plate and the second plate. The shoe cleaner may be configured with a brush plate mounted to two ring clamps for mounting to a tubular vehicle step. In another embodiment of the invention, a retractable cleaner pad is mounted to the frame of the vehicle.
US12162430B2 Method for unlocking an opening element of a motor vehicle and associated unlocking device
A device for “hands-free” unlocking/locking of a door of a motor vehicle includes a radiofrequency antenna and radiofrequency transmission/reception system to authenticate portable equipment of a user, at least one capacitive sensor to detect the approach and/or the contact of a member of the user in a predetermined zone, an electronic unit controlling the unlocking of the door, an emergency access device, and a chain. The emergency access device includes a body, a graspable pull member connected to a lock actuator and movable between retracted and deployed positions, a retention pin sliding transverse to the pull member, an electric ejector configured to control the sliding of the retention pin, and a control unit for the electric ejector adapted to control the electric ejector in two modes, the control unit controlling the electric ejector in vibration mode as a function of an authentication status of the equipment of the user.
US12162424B2 Airbag integrated display and control method for the same
Disclosed are an airbag integrated moving display and a control method where the airbag-integrated display includes a display movable to a forward or rearward position according to a driving mode of a vehicle, and an airbag mounted to the rear of the display and being configured to move along with a movement of the display, and vary a level of inflation of the airbag based on at least one of a position of the display or a distance from a driver of the vehicle.
US12162420B1 Vehicle airbag assembly
A vehicle includes a seat assembly having a seat bottom and a seatback. The vehicle includes a middle console adjacent the seat assembly. The vehicle includes an airbag inflatable from an uninflated position to an inflated position. The airbag is supported by the seatback in the uninflated position and the inflated position. The vehicle includes an inflator supported by the middle console, the inflator operatively connected to the airbag to provide inflation medium.
US12162416B2 Methods and systems for secure communication and authorization of vehicle mode change
Electrically powered accessories connected to vehicle power systems are authenticated, and connections between the accessories and the vehicle power systems are based on permissions resulting from that authentication. accessories may supply authentication information associated with an authentication level, and form a permitted connection based on the authentication level. Vehicle power systems may obtain the authentication information, obtain the authentication level, and operate a power connection according to the authentication level. Authentication information can be obtained from the component or from a user of the component through, for example, a portable device. A system may include the electrically powered component and the vehicle power system. The system may further include a remote server to process the authentication information and determine the authentication level.
US12162412B2 Vehicular camera system
A vehicular camera system includes a camera module having an imager assembly, a main circuit board and a camera housing. The imager assembly includes (i) an imager disposed on an imager circuit board and (ii) a lens holder having a lens assembly that includes a lens barrel accommodating a lens. The imager assembly includes a flexible ribbon cable that electrically connects to an electrical connector at a multilayered PCB of the main circuit board. The camera housing includes an upper cover and a lower cover and includes a forward portion and a rearward portion. The main circuit board is accommodated within the forward and rearward portions, and the imager is disposed at the rearward portion and is not disposed at the forward portion of the camera housing. The lens holder is attached at the upper cover of the camera housing.
US12162409B2 Article mounting system for a vehicle
A retainer has a base having a first side having an engagement member extending therefrom and a second side. The base comprising a base opening therethrough. A plunger has a body and a flange extending from the body. A lever member has a lever opening therethrough. The lever opening is sized to receive the body. The lever opening is smaller than the flange. A cover is coupled to the base. The cover comprises a first cover opening. The lever member comprises a first end rotatably coupled to the base or the cover or both. The lever has a second end extending through the first cover opening. A spring is disposed between the cover and the plunger. The spring is retractably urging the plunger into the first cover opening and the base opening.
US12162407B2 Vehicle monitoring system for providing alerts to drivers
A computing system uses a vehicle monitoring system to detect a change in at least one condition external to the vehicle. The system determines, using the vehicle monitoring system, whether a driver of the vehicle is using a computing device. Based on determining that the driver is using the computing device, the system outputs an alert.
US12162405B2 Digital license plate with active response to narrowband license plate recognition
A digital license plate includes a display system capable of showing a license number readable by camera systems even under poor external lighting conditions. A light redistribution element is positioned near the display system and a lighting system is positioned to direct light from the light redistribution element and toward the display system. In some embodiments the lighting system includes a narrowband lighting element such as can be provided by a narrowband light source, and the display system includes an electrophoretic or LCD display.
US12162404B2 System and method for creating a vehicle lighting atmosphere
A system for creating vehicle lighting atmosphere of a vehicle is provided. The system includes ambient lighting including a plurality of lights configured for illuminating an interior of the vehicle or an exterior of the vehicle with a selectable light color. The system further includes a computerized vehicle lighting controller, including programming to monitor an input useful to select an ambient lighting theme, select an ambient lighting theme based upon the input, and generate a command to control the ambient lighting based upon the ambient lighting theme.
US12162403B2 Drive assist apparatus for vehicle
A drive assist apparatus for a vehicle includes a turn signal drive unit, an environment information obtainer, and a controller. The controller includes a blinking cycle adjuster configured to cause the turn signal drive unit to drive with drive signals indicating blinking cycles different from each other. The blinking cycles include a first blinking cycle and a second blinking cycle shorter than the first blinking cycle. The blinking cycle adjuster is configured to set the first blinking cycle for the vehicle that travels at a first position, and set the second blinking cycle for the vehicle that travels at a second position closer to the intersection than the first position.
US12162399B2 Vehicle door light assembly
A vehicle door light assembly includes a base including a cavity and one or more bulb connectors positioned within the cavity; a connector for connecting the one or more bulb connectors to a power source; a lens assembly releasably connected to the base, wherein the lens assembly comprises: a lens, a light source adapted to emit light through the lens to the exterior of the light assembly, and a projector adapted to project an image to the exterior of the light assembly when the door is in an open position; and a bulb connector releasably connected to the one or more bulb connectors to supply power to the lens assembly.
US12162394B2 Vehicle floor covering system
A vehicle floor mat system comprising a vehicle floor tray molded from an extrusion polymer sheet, a vehicle floor mat affixation device containing a circular shaped body with axial extending tines, and a removable carpet attachment is disclosed. The vehicle floor mat system resists affixation device pull-out and shear forces applied to the mat with respect to the original equipment manufacturer's floor covering on which the mat is placed but allows for easy removal and replacement of the vehicle floor mat and of the affixation devices.
US12162393B2 Vehicle having deployable workstation
A vehicle includes a cabin interior, at least one seat located in the cabin interior, a support structure located near the at least one seat, and a workstation coupled to the support structure. The workstation includes a desk having a first desk panel and a second desk panel that moves relative to the first desk panel, a display screen, and a pivot mechanism coupled to the desk and the display screen and configured to allow the desk and the display screen to pivot relative to the support structure, wherein the desk and the display screen are configured to pivot to a vehicle downward position folded together and upward deployed use positions such that the desk may extend substantially horizontal in the use position and the display screen may extend upward relative to the desk.
US12162390B2 Electric wing-out headrest
An automatically operatable electric wing-out headrest includes a motor having a lead screw configured to adjust forward-and-rearward rotation of wing-out pads respectively mounted on the opposite sides of a headrest body, a first slider coupled to the lead screw so as to be movable upwards and downwards, a second slider configured to contact the first slider so as to be movable forwards and rearwards, and a wing-out link connected to the second slider to rotate a wing-out frame.
US12162387B2 Child restraint
A child restraint includes a seat bottom and a seat back coupled to the seat bottom. The seat back includes a backrest configured to extend upwardly from the seat bottom and a headrest coupled to the backrest for supporting a head of a child. The headrest includes a rear section arranged along the backrest, a first side section extending outwardly away from the rear section, and a second side section extending outwardly away from the rear section and away from the first side section.
US12162386B2 Backrest locking mechanism and child safety seat
A backrest locking mechanism adapted for a backrest and a base of a child safety seat is provided. The backrest is detachably connected to the base. The backrest locking mechanism includes a locking pin, a locking component and an operating component. The locking pin is disposed on the backrest. The locking component is disposed on the base. A locking hole structure is formed on the locking component. The locking pin is configured to detachably engage with the locking hole structure. The operating component is movably disposed on the backrest or the base. The operating component drives the locking pin and the locking hole structure to engage with or disengage from each other when the operating component is operated. Furthermore, a child safety seat having the aforementioned backrest locking mechanism is also provided.
US12162379B2 Seat assembly
A floating seat may have at least one seat shell with a seat surface region and a backrest region. The seat may also have a base element on which the seat shell is arranged in an adjustable manner, and an adjustment mechanism for adjusting the seat shell relative to the base element and/or a seat base. The adjustment mechanism has at least one adjustment unit for adjusting the seat shell and at least one drive unit which is designed to lock the base element and the seat shell in place in a self-locking manner. The lock can be released by a force introduced into the adjustment unit by an occupant sitting in the seat shell via said seat shell as well as by a force introduced into the adjustment unit by the drive unit.
US12162369B2 Network constraint energy management system for electric vehicle depot charging and scheduling
Network constraint energy management system for electric vehicle (EV) depot charging and scheduling. In an embodiment, a power schedule is received from an economic dispatch application for a charging depot comprising EV charging station(s) and distributed energy resource(s). The power schedule may be simulated on a distribution network model of the charging depot, according to load flow analysis, to determine whether any grid-code violations occur. In response to the detection of violation(s), a constraint may be generated for each violating node, and the economic dispatch application may be re-executed with the constraint(s) to produce a new power schedule, until no violations are detected. When not all load demand can be satisfied by the power schedule, a charging schedule may be adjusted to ensure that critical energy requirements are satisfied. The final power and charging schedules may be used to schedule and control power generation and charging in the charging depot.
US12162368B2 Computerized system and method for dynamic camera and scene adjustment for autonomous charging
The disclosed systems and methods provide a novel framework that provides mechanisms for a hands-free, autonomous electrical connection of an electric charger to an electric vehicle (EV), and subsequent charging. The disclosed framework utilizes an automated connection device (ACD) as an intermediary between the charger and the EV. The ACD is configured for automatically determining a precise location of the charging inlet on the EV and then automatically establishing an electrical connection with the EV so that the EV can receive a charge. The ACD performs the disclosed precise positional and directional navigation to the EV inlet based on deep neural network analysis of captured imagery of the inlet. In some embodiments, the images can be modified so as to highlight and/or assist the ACD's navigation towards to the inlet in order to maximize invariance.
US12162367B2 Method of configuring longitudinal wireless charging chain for electric vehicle and apparatus and system therefor
A method of configuring a longitudinal wireless charging chain by a first vehicle, includes detecting a second vehicle in which a longitudinal wireless charging chain is configurable; calculating a distance to the second vehicle; performing, based on the calculated distance being within a first distance, lateral alignment with the second vehicle; and performing, based on the calculated distance being within a second distance, longitudinal alignment with the second vehicle.
US12162366B2 Systems and methods for phase switch timing controller for inverter for electric vehicle
A system comprises an inverter configured to convert DC power from a battery to AC power to drive a motor, wherein the inverter includes: a galvanic isolator separating a high voltage area from a low voltage area; a low voltage phase controller in the low voltage area, the low voltage phase controller configured to receive a pulse width modulation (PWM) signal from an inverter controller and adjust the received PWM signal based on a feedback signal; and a high voltage phase controller in the high voltage area, the high voltage phase controller configured to receive the adjusted PWM signal from the low voltage phase controller, provide the adjusted PWM signal to a phase switch, and provide the feedback signal based on an on-time measurement of the phase switch.
US12162363B2 Modular system for dynamic tow and regenerative braking of a trailer
One variation of a system includes a bogie including: a chassis; a first set of latches configured to transiently engage a first subset of engagement features, in a first array of engagement features on a left rail and in a second array of engagement features on a right rail of the trailer, to retain the bogie below a floor of the trailer; a driven axle suspended from the chassis; and a motor coupled to the driven axle and configured to output torque to the driven axle and regeneratively brake the driven axle. The system further includes a battery assembly: including a second set of latches configured to transiently engage a second subset of engagement features, in the first array of engagement features and in the second array of engagement features, to retain the battery assembly adjacent the bogie; and configured to receive electrical energy from the motor.
US12162361B2 Method and apparatus for controlling driving force for dual-motor-equipped vehicle
According to an embodiment of the present disclosure, a driving force control apparatus for a vehicle includes: a front-wheel driver; a rear-wheel driver; a wheel speed detector; a wheel vibration calculator; an estimated speed calculator that calculates an estimated vehicle speed of the vehicle; a slip-rate calculator that calculates a slip rate of each wheel; and a driving controller that reduces a driving force of the front wheel driver or the rear wheel driver when a slip rate of each wheel is greater than a preset slip rate value. The estimated speed calculator determines that the estimated vehicle speed is greater than an actual speed of the vehicle when the vibration value calculated by the wheel vibration calculator is greater than a preset vibration value.
US12162358B2 Wheel drive apparatus
In a wheel drive apparatus, a clutch is configured to switch a coupling mode between a first rotating shaft of a first rotating electrical machine and a second rotating shaft of a second rotating electrical machine to any one of (i) a power transmission mode in which power transmission is enabled between the first rotating shaft and the second rotating shaft; and (ii) a power interruption mode in which power transmission is interrupted between the first rotating shaft and the second rotating shaft.
US12162356B2 Vehicle drivetrain
A vehicle comprising: first and second front electric motors, each front electric motor being coupled to a respective front wheel to drive that front wheel; a rear electric motor, an internal combustion engine, the internal combustion engine and rear electric motor being coupled to a rear axle to drive rear wheels; and three motor control units each comprising drive components, each motor control unit being coupled to a respective electric motor to drive that electric motor using the drive components, and the front and rear electric motors having a common set of physical characteristics so that each of the motor control units has identical drive components.
US12162352B2 Vehicle display control apparatus and vehicle display control method
A display controller converts a detection target region contained within a detection range of an obstruction sensor group and extending from a vehicle to the periphery thereof into a virtual marker image and causes a virtual image to be displayed by superimposing the image over a scene in front of the vehicle. When the relative position of an obstruction is within the detection target region, the display controller causes an arc-shaped ripple spreading in a direction based on the relative position of the obstruction to be displayed in a region, of the virtual marker image, located in a direction based on the relative position of the obstruction. The display controller converts the important information into a notification image and causes the notification image to be displayed in a display medium. The display controller changes the display format of at least one of the virtual marker image or the notification image.
US12162349B2 Controlling machine operation including limiting machine speed
According to one example, a system for control of a movement of a working vehicle within a work area is disclosed. The system can optionally include a steering system configured to direct the movement of the working vehicle, an object detection system, as speed sensor, and a controller. The object detection system can have one or more sensors configured to detect an object within the work area. The speed sensor can be configured to measure a speed of the working vehicle over a surface within the work area. The controller can be communicatively coupled to the steering system, the object detection system and the speed sensor. The controller can be configured to control the speed of the working vehicle based upon a steering angle of the working vehicle.
US12162341B2 Under body structure of automobile
An under body structure of an automobile enabling batteries to be mounted on an automobile by a simple configuration and efficiently transferring load at the time of a collision, that is, an under body structure 100 of an automobile provided with a body floor 110 forming a floor part of the automobile and batteries 50 (battery cells or battery modules) directly suspended from and fastened to a bottom side of the body floor 110.
US12162340B2 Drivetrain for an electric vehicle and electric vehicle comprising such a drivetrain
A drivetrain includes a main shaft, driven by an electric motor, and a wheel output shaft. Two gearwheels, mounted around the output shaft to rotate freely, are meshing with respective main pinions integral with the main shaft. A clutch system car engage either one of the gearwheel with the output shaft. To reduce the load applied to the gearwheels, the drivetrain includes a recirculation shaft, freely rotating relative to a housing of the drivetrain, and two recirculation pinion, integral with the recirculation shaft, each meshing with a respective gearwheel. When the clutch system engages one of the gearwheel with the output shaft, the recirculation shaft is driven by the main shaft through the other gearwheel meshing with the respective main and recirculation pinions, and the output shaft is driven both by the main and recirculation shafts, through the engaged gearwheel meshing with the respective main and recirculation pinions.
US12162335B2 Overmolding assembly reinforcement bracket
A liftgate (28) formed with a thermoplastic which is overmolded around preselected reinforcements at stress points, such as a corner area, which includes a pair of separate reinforcement plates (14,18) and wherein a 3-dimensional reinforcement plate (12) is connected between the pair of separate reinforcements (14,18). Preferably the 3-dimensional reinforcement plate is connected to three reinforcements.
US12162333B2 Electric lift gate and vehicle
The present disclosure relates to an electric lift gate and a vehicle. The electric lift gate includes: two side bars opposed and spaced apart, and the two side bars being provided with a guiding groove, respectively, the guiding groove extending along a length direction of the side bar; a roller shutter assembly disposed between the two side bars, two opposite sides of the roller shutter assembly being slidably disposed in the corresponding guiding grooves, respectively; a winding assembly cooperating with the roller shutter assembly in a driving manner; and a driving assembly connected to the winding assembly, and configured to drive the winding assembly to rotate, so as to drive the roller shutter assembly to wind or unwind.
US12162332B2 Frame structure of automotive exterior panel
A frame structure of an automotive exterior panel includes a sheet-like outer panel, a plurality of first members, each of which has an elongated shape, and which are disposed on a vehicle inside with respect to the outer panel, and a second member that has an elongated shape and intersects with the plurality of first members, in which each of the plurality of first members extends in a first direction along a sheet surface of the outer panel, and has a groove part recessed from the vehicle outside toward the vehicle inside at a portion thereof in a longitudinal direction, the second member extends in a second direction along the sheet surface of the outer panel, and has a thickness in a vehicle inside-outside direction, which is uniform at a portion closer to the center than at both end portions in the longitudinal direction, and at an intersection portion where each of the plurality of first members and the second members intersect with each other, the second member is in contact with the inside of the groove part provided in each of the plurality of first members.
US12162331B2 Systems with adjustable windows
A system such as a vehicle may have adjustable structures such as adjustable windows. Adjustable windows may have adjustable layers such as adjustable tint layers, adjustable reflectivity layers, and adjustable haze layers. Adjustable window layers may be incorporated into a window with one or more transparent structural layers such as a pair of glass window layers. Adjustable components such as adjustable reflectivity layers, adjustable haze layers, and adjustable tint layers may be interposed between the pair of glass window layers. Fixed partially reflective mirrors, fixed tint layers, and/or fixed haze layers may be used in place of adjustable tint, haze, and reflectivity layers and/or may be incorporated into windows in addition to adjustable tint, haze, and reflectivity layers.
US12162323B2 Mobile robot apparatus and controlling method thereof
A mobile robot apparatus includes a main body, a first wheel on a first side surface of the main body, a second wheel on a second side surface of the main body, where the first wheel and the second wheel include side surfaces having a convex shape, a first driving device configured to rotate the first wheel and the second wheel, a second driving device configured to move the first wheel and the second wheel to a first position or a second position, and a processor configured to, based on determining that the mobile robot apparatus is inverted to one side, control the second driving device to move a ground-engaging wheel from among the first wheel and the second wheel from the second position to the first position.
US12162319B2 Air suspension system
An air suspension system, includes an air suspension bellows connected to a vehicle frame, and an air suspension piston connected to a link, wherein the air suspension bellows and the air suspension piston are connected to each other and enclose an inner air volume, the air suspension piston has a rolling surface for rolling of the air suspension bellows, the air suspension bellows has a contact portion for rolling on the rolling surface, the rolling surface or the contact portion has at least one opening, wherein contacting areas of the rolling surface and the contact portion define a contact surface, and wherein a fluidic connection for an air flow through the at least one opening between the inner air volume and an environment is enabled and prevented by a change in the contact surface that includes a relative movement of the air suspension bellows to the air suspension piston.
US12162318B2 Vertical hi-rail device
A hi-rail device for mounting on a vehicle, comprising a locking slot comprising a first locking end and a second locking end, and a locking pin movable in translation within the locking slot and captured therein. The locking slot which is continuous between the first locking end and the second locking end, thereby being confined between the first locking end and the second locking end. A linkage is provided, and is foldable and unfoldable to displace an axle assembly for holding wheels. A spring-extended locking cylinder extends from the linkage to the locking pin, comprising a locking spring to urge the locking pin into the respective abutting surface of any one of the first locking end and the second locking end when the locking pin is in any one of them, thereby using only spring force in extension to lock the linkage into either locking position.
US12162317B2 Retention mount for trailer cord
A retention mount for an electrical cord of a trailer is described that includes a body, a tab extending away from the body, and a plurality of arms extending away from the body. The tab defines an opening configured to receive a plug of the electrical cord therethrough and the plurality of arms each include a retention portion extending outwardly from the body, such that a cable portion of the electrical cord can be wrapped around the plurality of arms with the retention portions thereof retaining the cable portion on the retention mount. The retention mount can be removably or irremovably coupled to a structure of a vehicle.
US12162315B2 Tire
A tire includes a tread portion including a first shoulder land portion provided with first shoulder lateral grooves extending from a first tread edge to a first shoulder circumferential groove, a second shoulder land portion provided with second shoulder lateral grooves extending from a second tread edge and terminating within the second shoulder land portion, a first middle land portion provided with first middle lateral grooves extending from the first shoulder circumferential groove and terminating within the first middle land portion, a second middle land portion provided with outer and inner second middle lateral grooves respectively extending from the second crown circumferential groove and the second shoulder circumferential groove and terminating within the second middle land portion, and a crown land portion provided with crown lateral grooves extending from the first crown circumferential groove and terminating within the crown land portion.
US12162314B2 Truck tire tread with angled ribs having stone ejectors
A heavy truck tire tread (12) is provided that has a tread groove (14) that is not oriented completely in the longitudinal direction so as to extend in both the longitudinal direction and the lateral direction. The tread groove is at least partially defined by a leading edge wall and a trailing edge wall and a bottom surface. A stone ejector (24) engages either the leading edge wall or the trailing edge wall but not both the leading edge wall and the trailing edge wall. The stone ejector faces the non-engaged leading edge wall or the trailing edge wall. Also, the tread has an average void depth that does not go past a twenty percent line (36). The twenty percent line (36) is twenty percent of a full void depth (40) located from the outer surface of the tread, and the average void depth does not include decouple grooves and tread outboard from them.
US12162311B2 Tire
In a tire, first and second center land portions each include a circumferential narrow groove and first and second lateral grooves. The first and second lateral grooves of the first center land portion are disposed overlapped with each other in a tire circumferential direction. The first and second lateral grooves of the second center land portion are disposed overlapped with each other in the tire circumferential direction. The first and second lateral grooves of the first center land portion are disposed offset with respect to the first and second lateral grooves of the second center land portion in the tire circumferential direction.
US12162310B2 Aircraft wheel and bearing protectors with integrated internal protection protrusion and fastening member guide and method of using same
An aircraft wheel hub protector is adapted to engage an aircraft wheel including an aircraft tire on a rim. The aircraft wheel hub protector having two or more cover sections with a protective protrusion and coupling mechanism guide extending from the a first cover section and passing through a bearing race and internal surface within a hub of the rim of the aircraft wheel in such a fashion so as to provide a void within the protective protrusion. The second cover section is engaged with an opposed side of the aircraft wheel from the first cover section. A coupling mechanism passes through the void in the protective protrusion without having contact with the bearing race and internal surfaces within the hub of the rim and coupling the first cover section and securing the aircraft wheel hub protector to the aircraft wheel.
US12162308B2 Emergency wheel
An attachment is provided for a vehicle wheel, having a rim and a tire arranged on the rim, for enabling a driving operation with a restricted tire function in an operating state in which the attachment is fastened on the vehicle wheel. The attachment may include a stationary section configured to be fastened immovably with respect to the rim in the operating state in which the attachment is fastened on the vehicle wheel, a tread section with a tread for contacting the road, and at least two clamping devices configured to engage behind a section of the rim to fasten the attachment on the vehicle wheel, wherein the tread includes at least one tread segment arranged movably in a circumferential direction with respect to the stationary section in the operating state in which the attachment is fastened on the vehicle wheel.
US12162305B2 Knock-type writing instrument
To provide a clicking type writing instrument capable of reliably suppressing volatilization of ink from the pen tip at least before the start of use. The clicking type writing instrument A has a refill 20 provided in a barrel cylinder 10; a pen tip 30 configured to discharge ink from an ink storage member 18 accommodated in the refill 20 by capillary action and to be allowed to be projected from and retracted into a front end of the barrel cylinder 10 by means of a clicking mechanism 70 provided in the barrel cylinder 10; and at least a seal member 40, arranged around an outer periphery of the pen tip 30 near a front end side of the pen tip, and formed with a through-hole 42 in a center of the seal member, through which the pen tip 30 can slidably move back and forth when the pen tip 30 is housed inside the barrel cylinder 10.
US12162304B1 Writing implement holder
The writing implement holder may be a device that is adapted to hold a writing implement on a user's finger such that movement of the user's finger may move a tip of the writing implement against a surface. As non-limiting examples, the writing implement holder may be adapted to be worn on an index finger, the writing implement may be a pen, a pencil, a marker, or a stylus, and the surface may be a sheet of paper, a tablet computer, or a smartphone. The writing implement holder may hold the writing implement to compensate for a lack of dexterity after an injury or illness, to avoid direct contact with the surface, or both. As non-limiting examples, injuries and illnesses that may reduce dexterity may include a heart attack, a stroke, arthritis, multiple sclerosis, or any combination thereof.
US12162303B1 Sodium alginate nanoparticles integrated with anthocyanidin biomolecules for optical validation
A thermochromic ink and, particularly, to a thermochromic ink produced by combining an anthocyanidin extract with alginate. The thermochromic ink can be used for authentication purposes produced by combining an anthocyanidin (ACYD)-based Brassica oleracea L. var. capitata extract with an alginate (ALG). To increase the anthocyanidin/alginate ink stability, a mordant (ferrous sulfate) can be used to link the anthocyanidin biomolecules with the alginate.
US12162301B2 Apparatus for transferring, fixing and polishing images printed on plastic or metal surfaces of three-dimensional objects
The object of this invention is to transfer, fix and polish images produced by: toner laser printers or inkjet printers, flexographic technology, silkscreen technology, offset technology, printed on reel support (A), on the plastic or metal surface of three-dimensional objects (16), thanks to which it is possible to detach images from the reel support (A) and subsequently transfer them to the surface of said plastic or metal objects (16) by a thermomechanical (1, 10) action.
US12162298B2 Manufacturing method of printed material
A manufacturing method of a printed material that stores machine-readable information, includes forming, on a base material, a first layer including a first code symbol that is machine-readable and represents first information, using a first coloring material, and forming, on the first layer, a second layer including a second code symbol that is machine-readable and represents second information, using a second coloring material that is different from the first coloring material and decolorable at a particular temperature, such that the first code symbol is at least partly covered by the second coloring material.
US12162295B2 Method of managing thermal printer and thermal printer for performing the same
Disclosed herein is a method of managing a printing apparatus including a thermal print head. The method of managing a printing apparatus includes: starting, by the controller of a printing apparatus, the cleaning of a thermal print head when a predetermined condition is satisfied; selecting, by the controller, a cleaning method based on at least one the satisfied condition and previously stored information; and cleaning, by the controller, the thermal print head by driving at least one of heating elements, included in a plurality of recording elements constituting the thermal print head, according to the selected cleaning method.
US12162293B2 Exposure head and image forming apparatus including exposure head
An exposure head configured to expose a photoreceptor includes a substrate having a plurality of light emitting portions, a lens array having a plurality of lenses that condense light emitted from the light emitting portions onto the photoreceptor, and a holder that holds the substrate and the lens array. The holder has an opposing surface including an opening into which the lens array is inserted and facing the photoreceptor in an optical axis direction of the lens. The opposing surface has a contacting surface on which a cleaning rod cleaning a light exit surface of the lens array abuts. The holder includes a sealing agent that seals a gap between a side wall of the lens array and an edge of the opening along a longitudinal direction of the holder, and a groove formed in the opposing surface between the opening and the contacting surface. The sealing agent is applied between the groove and the side wall.
US12162289B2 Inkjet printing apparatus
An inkjet printing apparatus includes an inkjet head that moves in a main scanning direction at the time of printing; a filter chamber provided on a path for supplying ink to a nozzle hole (nozzle) in the inkjet head; and a spherical body placed on a head filter in the filter chamber. The spherical body has a diameter φ larger than the mesh of the head filter. The spherical body is disposed on the head filter so as to be rollable by the movement of the inkjet head.
US12162286B2 Recording apparatus
A recording apparatus includes a recording head having discharge orifices arranged on a discharge orifice surface, a cap, a wiper, and a moving unit that moves the wiper in a first direction. When the cap covers the discharge orifice surface, a first member is disposed at an inside wall of the cap at a position near a first side of a region having the discharge orifices, and a second member is disposed at another inside wall of the cap at a position near a second side of the region having the discharge orifices. The first side faces in a direction opposite to the first direction and the second side faces in the first direction. In a direction normal to the discharge orifice surface, a distance between the second member and the discharge orifice surface is smaller than a distance between the first member and the discharge orifice surface.
US12162283B2 Liquid ejection head and process for producing liquid ejection head
A liquid ejection head includes a base plate and at least two device chips in which ejection ports for ejecting a liquid are formed and which are disposed on the base plate. At least one first reference mark is provided on the base plate. A second reference mark is provided on each of the device chips. At least one space is formed between adjacent device chips. The second reference marks and the first reference mark present in the space are disposed on an array axis along which the device chips are arrayed.
US12162280B2 Printing apparatus having operating mode in which ink ejection is shared by first head and second head at prescribed contribution ratio
In a printing apparatus, a carriage is reciprocally movable in first and second directions. A control device is configured to perform executing one of first and second printing operations in accordance with an operation mode. The first printing operation prints a first image over a first range in a third direction crossing the first and second directions by ejecting ink from both first and second heads during one movement of the carriage in the first and second directions. The second printing operation prints a second image over a second range narrower than the first range in the third direction by ejecting ink from both the first and second heads during the one movement of the carriage. Ink ejection contribution during the one movement of the carriage is shared by the first and second heads at a prescribed contribution ratio in the second printing operation.
US12162278B2 Method for controlling driving of inkjet head, and inkjet recording apparatus
There is provided a method for controlling driving of an inkjet head including recording elements each including a nozzle and a driving element. The method includes a pulse width setting step. In this step, when a predetermined number of ink droplets ejected according to the predetermined number of driving pulses are made to land in the same pixel range, the predetermined number of first driving pulses each having a pulse width longer than a reference pulse width and the predetermined number of second driving pulses each having a pulse width shorter than the reference pulse width are combined for each of the recording elements and obtained combinations are respectively output to the recording elements. The predetermined number is two or more.
US12162277B2 Liquid discharge device and drive circuit substrate
A liquid discharge device in which a drive circuit substrate that outputs a first drive signal supplied to a first electrode, a substrate, a first drive circuit that has a first circuit element in which a ground potential is supplied to one end and outputs the first drive signal, a first capacitor in which one end is electrically coupled to the second electrode and a ground potential is supplied to the other end, and a second capacitor in which one end is electrically coupled to the second electrode and a ground potential is supplied to the other end, the substrate includes a first surface and a second surface, the first capacitor is a chip capacitor, the second capacitor is an electrolytic capacitor, the first circuit element and the first capacitor are provided on the first surface, and the second capacitor is provided on the second surface.
US12162272B2 Roll paper printer
A roll paper printer includes a container that can accommodate a roll paper around which a recording paper sheet is wound with its first surface facing outward. A transport roller pulls the recording paper sheet from the roll paper and then transports the recording paper sheet in a transport direction. A guide can be in contact with a second surface of the recording paper sheet at a location upstream of the transport roller in the transport direction. A projection can be in contact with the first surface of the recording paper sheet at another location upstream of the transport roller in the transport direction and move toward the guide. A lever can be accommodated in the projection and move in contact with the first surface of the recording paper sheet. A sensor is accommodated in the projection and detects motion of the lever.
US12162267B2 Image forming apparatus configured to accommodate roll media and cut media and feed tray therefor
An image forming apparatus includes a housing, a feeding tray inserted into and pulled out from the housing, an image forming unit, and first and second guide members. The feeding tray includes a first accommodation part in which a roll body having a configuration where a sheet-shaped medium is rolled in a roll shape is accommodated and a second accommodation part in which stacked sheet-shaped media are accommodated. The first guide member guides a sheet-shaped medium to a conveying path. The second guide member guides a roll medium unrolled from the roll body to the conveying path. The second guide member is movable between a guide position for guiding the roll medium to the conveying path, and a retreat position further distant from the first guide member than the guide position and where the second guide member does not interfere with a sheet-shaped medium accommodated in the second accommodation part.
US12162265B2 Offset print apparatus and methods
Offset print apparatus comprises a blanket arranged in a closed loop around a plurality of rollers. Each of the plurality of rollers is rotatable about a respective roller axis to support and convey the blanket around the closed loop. The plurality of rollers comprises: a primary steering roller rotatable about a primary roller axis and being pivotable about a primary steering axis perpendicular to the primary roller axis; and a secondary steering roller rotatable about a secondary roller axis and being pivotable about a secondary steering axis perpendicular to the secondary roller axis. The primary and secondary steering rollers are each independently pivotable. The offset print apparatus further comprises an actuator to actuate pivoting of the primary steering roller and the secondary steering roller.
US12162259B2 Biodegradable foam with laminate layers
A composite material includes a porous foam, having a density of less than 1 g/cm3, with a polymer matrix including chitosan, chitin, or chitosan oligosaccharide, and a first laminate adhered to a first surface of the porous foam.
US12162258B2 Method to produce a coating layer, a building panel and a coated foil
The present disclosure relates to a method to produce a coating layer, including applying a coating composition on a surface of a carrier, curing the coating composition to a coating layer, and subsequently applying pressure to the coating layer. The disclosure further relates to a method to produce a building panel, and such a building panel, and to a method to produce a coated foil, and such a coated foil.
US12162257B2 Metal clad laminated plate and method for manufacturing metal clad laminated plate
A method for manufacturing a metal clad laminated plate includes hot pressing a laminated body by a double belt press method. The laminated body includes an insulating film containing the liquid crystal polymer and the metal foil lying on the insulating film. In hot pressing the laminated body, a highest heating temperature is higher than or equal to a temperature lower than a melting point of the insulating film by 5° C. and lower than or equal to a temperature higher than the melting point by 20° C. The highest heating temperature is maintained for longer than or equal to 20 seconds and shorter than or equal to 120 seconds.
US12162256B2 Fusion panel and application
A fusion panel includes a first panel member, a second panel member, a first layer and a second layer, wherein the first layer is overlapped and fused with the second layer. Edges of the first panel member and the second panel member are connected to each other to form a cavity therebetween with a hollow structure. The first panel member is constructed to have at least one of a portion of the first layer and a portion of the second layer. The second panel member is constructed to have at least one of a portion of the first layer and a portion of the second layer.
US12162253B2 Thin wall lubricious polyethylene liners
The disclosure provides tubes including a blend of two or more polyethylenes. For example, the blend can comprise at least 80% by weight of one or more of LLDPE, LDPE, MDPE, and HDPE, and no more than 20% by weight of UHMWPE. Such tubes can have low average wall thicknesses, e.g., 0.1 mm or less, rendering them suitable for use as catheter liners.
US12162247B2 Composite pane comprising a functional element having electrically controllable optical properties and having a concentration gradient of the active substance
A composite pane includes a functional element having electrically controllable optical properties, includes an inner pane including an inner and outer side and an outer pane including an inner and outer side, a thermoplastic intermediate layer, which joins the inner side) of the inner pane to the inner side of the outer pane, a functional element embedded in the thermoplastic intermediate layer and having electrically controllable optical properties at least including a multilayer film containing, arranged surface-to-surface one above the other in this sequence, a first carrier film, a first surface electrode, an active layer, a second surface electrode, and a second carrier film. The active layer includes a matrix and an active substance, and the concentration of the active substance varies over the area of the functional element.
US12162246B2 Asymmetrical glass laminates having a TPU interlayer and related methods
Various embodiments for a laminate glass article and related methods are provided. The laminated glass article includes a first glass layer and a second glass layer with a TPU interlayer positioned therebetween.
US12162240B2 Embossing group
An embossing group includes: a first embossing roller and at least one embossing unit associated with the first roller. The embossing unit includes a second embossing roller, a third embossing roller, and a sleeve surrounding the second roller and the third roller by coupling them. The sleeve faces the first roller and is configured to contact the first roller. The embossing unit and the first roller are configured to emboss at least one paper sheet wound between the first roller and the embossing unit.
US12162239B2 System with arcuate slot for feeding sheet material
A dunnage conversion system (100) includes a supply area (120), a dunnage conversion machine (110), and an arcuate slot (130). The supply area (120) is configured to hold a supply of a sheet material (122). The sheet material (122) is in a substantially flat configuration in the supply area (120). The dunnage conversion machine (110) is configured to pull the sheet material (122) from the supply area (120) and to convert the sheet material (122) into a non-flat configuration. The arcuate slot (130) is positioned between the supply area (120) and the dunnage conversion machine (110) such that the sheet material (122) is fed through the arcuate slot (130) as the sheet material (122) passes along a path from the supply area (120) to the dunnage conversion machine (110).
US12162237B2 Box-forming apparatus
A box forming apparatus comprising a machine frame, and an outer mould and an inner mould arranged on the machine frame for forming a blank into a box. The outer mould and the inner mould are configured to be movable relative to one another along a pressing direction between an open configuration and a pressing configuration, for receiving the blank between the outer and inner moulds in the open configuration, for subsequently pressing the blank in the pressing configuration to form the box, and for discharging the box in the open configuration after pressing and forming the box. The outer and inner moulds comprise mould element sets of an outer mould element and an associated inner mould element, wherein the outer mould elements define the outer mould and the inner mould elements define the inner mould, and the outer mould element and the inner mould element of each mould element set are movable relative to one another along the pressing direction between positions associated with the open configuration and the pressing configuration, and wherein the mould element sets are movable relative to another along a plane transverse to the pressing direction to allow adjusting to dimensions of the box to be formed.
US12162235B2 Methods of bladder molding at least a portion of an upper for an article of footwear
Methods for manufacturing at least a portion of an upper for an article of footwear that include thermo-forming a pattern on the upper. The methods may include disposing a skin for forming an upper over and inflatable bladder and disposing a mold insert between the skin and a surface of a mold cavity. The mold insert may include a mold pattern including surface features formed in the mold insert. The inflatable bladder may be inflated such that the skin is pressed against the mold insert within a heated mold cavity to form a pattern on an exterior surface of the skin and cause the skin to take on the shape of at least a portion of an upper. In some embodiments, the surface features may be disposed in a gradient pattern configured to provide varying degrees of one or more characteristics to different areas of an upper.
US12162234B2 Transfer ring shoe and transfer ring with reduced air entrapment features
A transfer ring for use in the manufacture of tires comprises a radially expandable and collapsible segmented gripping surface defined by a plurality of shoes, each shoe having an inwardly-facing surface mounted for movement toward and away from a central axis of the cylindrical gripping surface. Each inwardly-facing surface has first and second side edges. Each side edge has a central portion configured to be substantially parallel to a central portion of the other side edge and forms a mid-portion therebetween. Each side edge has first and second tapered portions on opposite respective ends of the central portion. Each tapered portion extends toward a tapered portion of the other side edge. The tapered portions cooperate to form a end portions that decrease in width away from the mid-portion.
US12162233B2 Tire unloading unit for unloading a green tire
A tire unloading unit for unloading a green tire, wherein the green tire has an externally facing circumferential tread surface extending around a tire axis, wherein the tire unloading unit has a base and a support for supporting the green tire relative to the base at the externally facing circumferential tread surface from below and an upper arm projecting from the base for stabilizing the green tire at the externally facing circumferential tread surface from above, wherein the upper arm includes a first lateral boundary member, a second lateral boundary member and intermediate boundary members which are individually movable to closely adapt to the contour of the green tire and remain in contact with said contour even when the green tire collapses slightly over time.
US12162230B2 Optical articles comprising encapsulated microlenses and methods of making the same
The present disclosure includes optical articles comprising a lens having first and second lens surfaces and a protective layer having first and second protective surfaces that is coupled to the lens such that the first protective surface is disposed on the second lens surface. The optical article can comprise a plurality of convex or concave optical elements defined on the second lens surface or the first protective surface. The protective layer can have a maximum thickness larger than a maximum height of each of the optical elements such that the protective layer encapsulates the optical elements.
US12162227B2 Method for manufacturing a grille for a thrust reverser
The invention proposes a method for manufacturing a grille for a cascade type thrust reverser, of a jet engine, said method including the following steps: a) manufacturing a first component comprising long fibres, pre-impregnated by a thermoplastic or thermosetting resin; b) manufacturing, together with step a), a series of second components each including discontinuous fibres, pre-impregnated by a thermoplastic or thermosetting resin, step b) being carried out such that the second components are, on the one hand, arranged to transversally with respect to a longitudinal direction of the first component on at least one side of the first component and, on the other hand, spaced from one another according to this longitudinal direction, so as to form a comb-shaped structure, wherein the second components are consolidated to the first component.
US12162225B2 Automated ultrasonic welding of cable ties
A feedback control system for use with ultrasonic welding. A weld energy set point and/or a reference power curve are used by a controller to provide a power supply voltage set point and a power supply frequency set point for the power that is to be drawn by an ultrasonic weld generator. Information regarding the actual voltage and/or frequency of the drawn electrical power, and/or the frequency and magnitude of an ultrasonic wave transmitted from the generator to an applicator tool used to weld an object can be utilized by an estimator to estimate the weld energy dissipated at the weld site and/or generate a power curve for the welding operation. Using information from the estimator, the controller can determine adjustments for variables for the current and/or future welding operations. Further, welding may not commence until a clamping force exerted on the object satisfies a clamping force set point.
US12162224B2 Fluid-filled cushioning article with seamless side walls and method of manufacturing
A method of manufacturing a cushioning article comprises wrapping a polymeric sheet around a support so that the polymeric sheet surrounds a perimeter of the support. A first portion of the polymeric sheet adjacent a first side edge of the polymeric sheet overlaps and is stacked on a second portion of the polymeric sheet adjacent a second side edge of the polymeric sheet. The first portion is welded to the second portion at a first weld disposed between the first side edge and the second side edge while the polymeric sheet is wrapped around the support so that the polymeric sheet forms an open-ended sheath with a top wall, a bottom wall, a first side wall and a second side wall with the first weld disposed at only one of the top wall and the bottom wall. A cushioning article manufactured according to the method is disclosed.
US12162223B2 Electroweld fitting
An electroweld fitting is made of plastic material for welding plastic pipelines. The electroweld fitting has: a cylindrical body having a longitudinal axis; a heating wire winding; contacts configured to conduct an electric current; and a pipe stop. The pipe stop is arranged on an inner lateral surface of the cylindrical body. The pipe stop is flexible and resilient. The cylindrical body and the pipe stop arranged thereon are a one piece injection molded part. The heating wire winding is an embedded wire in the inner lateral surface of the cylindrical body.
US12162222B2 Method for calibrating a device for producing a three-dimensional object and device configured for implementing said method
A calibration method serves for calibrating a manufacturing device for additively producing a three-dimensional object by applying layer by layer and selectively solidifying a building material. The manufacturing device comprises at least two scanning units, each of which is capable of directing a beam to different target points in the working plane, which are located within a scanning region assigned to the respective scanning unit, wherein the scanning regions region of the at least two scanning units overlap in an overlap area. At least a first of the at least two scanning units is assigned a first monitoring unit whose monitoring region extends to a target point of the first scanning unit and its proximity, wherein a change of a position of the monitoring region is carried out as a function of a change of a position of the target point.
US12162221B2 Additive manufacturing build units with process gas inertization systems
A build unit for additively manufacturing three-dimensional objects may include an energy beam system having one or more irradiation devices respectively configured to direct one or more energy beams onto a region of a powder bed, and an inertization system including an irradiation chamber defining an irradiation plenum, one or more supply manifolds, and a return manifold. The one or more supply manifolds may include a downflow manifold configured to provide a downward flow of a process gas through at least a portion of the irradiation plenum, and/or a crossflow manifold configured to provide a lateral flow of the process gas through at least a portion of the irradiation plenum. The return manifold may evacuate process gas from the irradiation plenum. While irradiating the region of the powder bed, the process gas may flow through the one or more supply manifolds, into the irradiation plenum, and into the return manifold.
US12162220B2 Method of smoothing a surface of an additively manufactured part
The present invention provides apparatus for post-processing an additively manufactured polymer part, comprising a reservoir (402) for containing a liquid solvent; a processing chamber (408) in controllable fluid communication with the reservoir, and a controller (418) configured to controllably post-process an additively manufactured polymer part located in the processing chamber by the solvent responsive to at least one parameter associated with the part. A method for post-processing an additively manufactured polymer part is also provided.
US12162218B2 Modular expandable 3D printer
A modular and expandable 3D printer frame includes frame members to be coupled together to form a base defining an inner area. Each frame member includes at least one coupling member to removably couple the frame member to another of the frame members. The printer frame further includes first modular plates to be disposed within the inner area, and second modular plates to be disposed within the inner area and removably coupled to the first modular plates. The first and second modular plates, when coupled together, define a printer footprint.
US12162215B2 Method and apparatus for continuous composite three-dimensional printing
A method and apparatus for the additive manufacturing of three-dimensional objects are disclosed. Two or more materials are extruded simultaneously as a composite, with at least one material in liquid form and at least one material in a solid continuous strand completely encased within the liquid material. A means of curing the liquid material after extrusion hardens the composite. A part is constructed using a series of extruded composite paths. The strand material within the composite contains specific chemical, mechanical, or electrical characteristics that instill the object with enhanced capabilities not possible with only one material.
US12162212B2 Method for the preparation of a cell culture insert with at least one membrane
A method for producing a cell culture insert with at least one membrane, in particular at least one biological membrane, may include the following steps: providing at least one insert blank with at least one opening; and forming the at least one membrane in the insert blank by means of a bio-printing method.
US12162205B2 Gripper for a draping frame and for a device, draping frame, device and method for the forming of and/or covering using a film element, system for manufacturing a moulded part or a covered component, method for retro-fitting a device of this type, method for manufacturing a covered component
A gripper is disclosed for a draping frame having a gripper chassis and at least two opposing mutually movable gripper jaw elements for gripping a film element. The gripper jaw elements are provided on a gripper head part of the gripper. The gripper head part of the gripper is movably mounted, at least with one degree of freedom, relative to the gripper chassis.
US12162204B2 Electric heated base for container blow-molding device
A device for blow molding a container from a preform. The device includes a mold base and a pedestal for supporting the mold base. An electric heating element is beneath the mold base for heating the mold base. An insulator is between the heating element and the pedestal.
US12162199B2 Method, apparatus and press for injection moulding of plastic material
A method, apparatus and press for the injection moulding of plastic material by a plurality of injectors connected to a distributor and provided with respective obturators movable between a closing condition and an opening condition in a controlled fashion. The injection pressure in the distributor is maintained substantially constant by an actuator which actuates a screw of the injection press, from a start of a filling step up to an end of a packing step of the plastic material into a cavity of a mould. A moulding cycle is entirely controlled by each injector, by managing the position/velocity/acceleration of the respective obturator, without affecting the other injectors.
US12162188B2 Anti-ablative coating material for resin-based composite material and preparation method therefor
A resin matrix composite used as anti-ablation coating material and its preparation method is provided. The resin matrix composite is a mixture of yttria-stabilized zirconia (YSZ), a resin, Cu, and SiO2. The mixture is uniform and include spherical particles or spherical aggregates. A method for preparing a resin matrix composite for anti-ablation coating includes mixing YSZ, a resin, Cu, and SiO2 to obtain a mixed powder and performing spray granulation of the mixed powder to obtain a resin matrix composite including spherical particles or spherical agglomerates.
US12162187B2 Powder storage apparatus, melt kneader, powder storage method, and production method for thermoplastic resin composition
A powder storage apparatus 41 includes: a container 42 having a powder inlet 18A, a powder outlet 10A, and a gas outlet 18B; and a tube 70 connected to the powder inlet 18A. If AS [m2] is a cross-sectional area of a cross section perpendicular to an axis of the tube 70 at a bottom end 70b of the tube 70 and AB [m2] is a cross-sectional area of the gas outlet 18B, the following expression is satisfied. AS/AB<4.
US12162185B2 Fiber-reinforced resin prepreg, molded article, and fiber-reinforced thermoplastic resin prepreg
A fiber-reinforced resin prepreg and a molded article obtained by molding a molding material including the fiber-reinforced resin prepreg are described. The fiber-reinforced resin prepreg contains a carbon fiber bundle and a matrix resin composition. The ipa value of the carbon fiber bundle measured by an electrochemical measurement method is 0.14 μA/cm2 or more. The impact strength of a film obtained by solidifying the matrix resin composition under particular molding conditions is 12.0 kJ/m or more.
US12162182B2 Reinforcement of 3D-printed concrete bodies
A method for producing a component from hardenable material, wherein, in a first method step, at least one layer of the material is printed in a 3D printing process, in a second method step, multiple similar reinforcing elements are introduced into the layer(s) and the two method steps are cyclically repeated until the component is completed, characterized in that, with the exception of the two bottommost and the topmost layers, each reinforcing element extends over at least three layers, and the reinforcing elements are arranged in strands which extend through all the layers and have, in each layer, at least three reinforcing elements, the lateral distance (A) of these reinforcing elements from each other within a strand being a maximum of five times the largest lateral extent (D) of a reinforcing element.
US12162172B2 Staged advice for optimal use of a shaving device
A method, a personal care system and a shaving device for providing staged shaving advice include a processor configured to receive usage data from the shaving device and personal assessment data from a user. The processor is further configured to determine and provide a shaving advice instruction presented to the user based on the usage data and/or the personal assessment data.
US12162166B2 Robotic system with error detection and dynamic packing mechanism
A method for operating a robotic system includes determining a discretized object model based on source sensor data; comparing the discretized object model to a packing plan or to master data; determining a discretized platform model based on destination sensor data; determining height measures based on the destination sensor data; comparing the discretized platform model and/or the height measures to an expected platform model and/or expected height measures; and determining one or more errors by (i) determining at least one source matching error by identifying one or more disparities between (a) the discretized object model and (b) the packing plan or the master data or (ii) determining at least one destination matching error by identifying one or more disparities between (a) the discretized platform model or the height measures and (b) the expected platform model or the expected height measures, respectively.
US12162165B2 System and/or method for robotic foodstuff assembly
The foodstuff assembly system can include: a robot arm, a frame, a set of foodstuff bins, a sensor suite, a set of food utensils, and a computing system. The system can optionally include: a container management system, a human machine interface (HMI). However, the foodstuff assembly system 100 can additionally or alternatively include any other suitable set of components. The system functions to enable picking of foodstuff from a set of foodstuff bins and placement into a container (such as a bowl, tray, or other foodstuff receptacle). Additionally or alternatively, the system can function to facilitate transferal of bulk material (e.g., bulk foodstuff) into containers, such as containers moving along a conveyor line.
US12162156B2 Robotic manipulation planning based on probalistic elastoplastic deformation material point method
A robotic manipulation planning system, including at least one processor; and a non-transitory computer-readable storage medium including instructions that, when executed by the at least one processor, cause the at least one processor to: process perception data to detect known, familiar, and unknown objects to generate manipulation candidates; filter manipulation candidates against constraints to reduce the manipulation candidates; and determine quality metrics for the reduced manipulation candidates using a soft-body simulation technique.
US12162152B2 Machine-learning device
Provided is a machine-learning device which can efficiently perform machine learning. The machine-learning device comprises: a vision execution unit which captures an image of an object W by means of a visual sensor by executing a vision execution command from a robot program, and detects or determines the object W from the captured image; a result acquisition unit which acquires the detection result or the determination result for the object W by executing a result acquisition command from the robot program; an additional annotation unit which gives a label to the captured image on the basis of the detection result or the determination result for the image of the object W by executing an annotation command from the robot program, and acquires new training data; and a learning unit which performs machine learning by using the new training data by executing a learning command from the robot program.
US12162150B2 Learning method, learning apparatus, and learning system
A robot control device includes at least one memory, and at least one processor, wherein the at least one processor is configured to obtain environmental information in a real environment, obtain information related to an action to be performed by a robot in the real environment based on the environmental information and a first policy, obtain information related to a control value that causes the robot to perform the action based on the information related to the action and a second policy, and control the robot based on the information related to the control value. The first policy is learned by using a virtual robot in a simulation environment.
US12162138B2 Systems, devices, and methods for robotic end effectors
A robotic end effector or end-of-arm tool may take the form of a mechanical digit (e.g., mechanical finger), or employ one or more mechanical digits (e.g., mechanical fingers), controllable in multiple degrees of freedom, e.g., pitch, yaw, curl. The mechanical digit(s) advantageously comprise a skeleton and three (3) piston/cylinders combinations, one controlling curl, and the other two controlling pitch and/or yaw. Mechanical digits may comprises a number of rolling contact joints. A flexible printed circuit board (PCB) carrying a variety of sensors covers the skeleton, and runs inside the rolling contact joints to provide a zero length change path. Knuckle imitators may cause a membrane cast or sheath joint to resemble human knuckles.
US12162136B2 Method and apparatus for estimating touch locations and touch pressures
A tactile sensing system of a robot may include: a plurality of piezoelectric elements disposed at an object, and including a transmission (TX) piezoelectric element and a reception (RX) piezoelectric element; and at least one processor configured to: control the TX piezoelectric element to generate an acoustic wave having a chirp spread spectrum (CSS) at every preset time interval, along a surface of the object; receive, via the RX piezoelectric element, an acoustic wave signal corresponding to the generated acoustic wave; select frequency bands from a plurality of frequency bands of the acoustic wave signal; and estimate a location of a touch input on the surface of the object by inputting the acoustic wave signal of the selected frequency bands into a neural network configured to provide a touch prediction score for each of a plurality of predetermined locations on the surface of the object.
US12162135B2 Managing shared robots in a data center
An embodiment includes identifying a robot that is available to perform a task involving an asset in a data center. The embodiment transmits a script to the robot that includes commands corresponding to actions to be executed by the robot in performing the task and transmits a dispatch command to the robot configured to enable the robot to travel from a robot resting place to the asset to begin the task. The embodiment relays a verification request received from the robot after the robot has completed a portion of the task to the vendor. The embodiment also relays, responsive to the verification request, an updated script based on updated instructions from the vendor for dynamically modifying the task to correcting an irregularity. The embodiment transmits, responsive to completion of the task, a recall command to the robot configured to enable the robot to travel from the asset to the robot resting place.
US12162134B2 System with substrate carrier deterioration detection and repair
A system includes a plurality of semiconductor processing tools; a carrier purge station; a carrier repair station; and an overhead transport (OHT) loop for transporting one or more substrate carriers among the plurality of semiconductor processing tools, the carrier purge station, and the carrier repair station. The carrier purge station is configured to receive a substrate carrier from one of the plurality of semiconductor processing tools, purge the substrate carrier with an inert gas, and determine if the substrate carrier needs repair. The carrier repair station is configured to receive a substrate carrier to be repaired and replace one or more parts in the substrate carrier.
US12162132B2 Shed organizing systems including self-leveling mounting plates and tool supporting sections
A shed organizing system includes a first tool organizing device having a first mounting plate and a first tool supporting section that extends from the first mounting plate, and a second tool organizing device having a second mounting plate and a second tool supporting section that extends from the second mounting plate. A shed includes an exposed vertical stud having a first major surface that extends along a first side of the exposed vertical stud and a second major surface that extends along a second side of the exposed vertical stud. The first mounting plate is secured to said the major surface of the exposed vertical stud and the second mounting plate is secured to the second major surface of the exposed vertical stud.
US12162131B2 Housing clamp for a power tool
The present invention relates to a housing clamp for a power tool housing, such as a drill, router, grinder, impact wrench, ratchet wrench, screwdriver, or other powered tool. The housing clamp includes a circumferential flange and recess that extends at an angle. When the housing clamp is installed, the housing clamp couples two portions of a power tool housing together. As the housing clamp is tightened onto the housing portions, the flange loads the housing with even pressure around its circumference providing a clamping load. The housing clamp provides even pressure around a large area at a working end of the tool, allowing the tool to be thinner in a dimensionally critical area.
US12162129B2 Work machine
A cutting tool 10 comprises a housing 30, and a handle 50 connected to the housing 30. The handle 50 comprises: a grip part 51; a first connection part 52 extending from one end of the grip part 51 toward a front side and fixed to a main body housing 32 of the housing 30; and a second connection part 53 extending from the other end of the grip part 51 toward the front side and fixed to the main body housing 32. Thus, a loop structure S is formed by the housing 30 and the handle 50. Then, a battery pack 100 to be attached to a battery attachment and detachment part 42 of a motor housing 40 is disposed in the loop structure S.
US12162122B2 Track processing machine, in particular impact wrench machine, and process for track processing by a track processing machine
A track processing machine, in particular an impact wrench machine for track processing, contains at least one handle for manually guiding the track processing machine, a first structural unit with a processing head, which can be driven in rotation for track processing about an axis of rotation, a second structural unit, and a linking unit for mechanically connecting the first structural unit to the second structural unit and for reducing a longitudinal dimension of the track processing machine along the axis of rotation.
US12162116B2 Double-side or one-side machining machine
A machining machine comprises a first support disk, a first working disk coupled to the first support disk, and a counter bearing element positioned to define a working gap between the first working disk and the counter bearing element. The first working disk and the counter bearing element are configured to rotate relative to each other to machine at least one side of a flat workpiece. A pressure volume is positioned between the first support disk and the first working disk and is configured to hold a pressure fluid, which generates a pressure configured to deform the first working disk. One or more temperature-controlling channels are positioned within the first working disk and configured to hold a temperature-controlling fluid that is configured to control a temperature of the first working disk, wherein the one or more temperature-controlling channels are fluidly separate from the pressure volume.
US12162115B2 Chamber components with polished internal apertures
Disclosed herein is a plasma-resistant chamber component and a method for manufacturing the same. A plasma-resistant chamber component of a semiconductor processing chamber that generates a plasma environment includes a ceramic article having multiple polished apertures. A roughness of the multiple polished apertures is less than 32 μin.
US12162109B2 System and method for contouring edges of airfoils
A tool for contouring an airfoil comprises a main body that includes a locator portion and an upper portion. The locator portion includes an engagement surface and the engagement surface is sized and configured to engage an airfoil. The upper portion includes an edge slot sized and configured for placement of an edge of the airfoil into the slot. An abrasive material is applied to the sides of the edge slot. The upper portion and the locator portion are together sized and shaped so that when the edge of the airfoil is disposed in the edge slot and the engagement surface of the locator portion is simultaneously pressed against the airfoil, engagement of the abrasive material with the edge of the airfoil is effective to contour the edge of the airfoil to a preselected and desired shape.
US12162106B2 Method of assembling a structure in aircraft or spacecraft production
A method of assembling a structure in aircraft or spacecraft production wherein two components to be joined together at a joint are provided, each component comprising a joining region. Sealant is applied to one of the component joining regions. An arrangement is formed by positioning the components relative to each other, whereby an uncured layer of the sealant is formed between associated joining regions. The associated joining regions are clamped against each other using a clamping device, and a clamped state is maintained until the layer of sealant has cured to a pre-defined degree, the clamping device being installable on and transportable along with the arrangement. After the layer of sealant has cured to the pre-defined degree, drilling at a plurality of fastening positions is performed to obtain a hole of final dimension at each fastening position, and installation of a final fastener at each fastening position is performed.
US12162105B2 Spray containment systems and welding gun nozzle cleaning systems including spray containment systems
An anti-spatter spray containment system includes: an enclosure having a nozzle insertion orifice on a first side and a drain orifice on a second side of the enclosure; a spray nozzle configured to spray fluid toward a nozzle inserted into the nozzle insertion orifice, wherein the enclosure is configured to funnel the fluid in a direction toward the second side; and a baffle configured to block at least a first portion of sprayed fluid from the spray nozzle from exiting the enclosure via the nozzle insertion orifice, the first side configured to block at least a second portion of the sprayed fluid from the spray nozzle that is not blocked by the baffle.
US12162104B2 System and method for servicing welding torches
Systems for servicing welding torches are provided, which include a feeder assembly and a nozzle cleaning assembly. The feeder assembly may be configured to feed removable components (e.g., contact tips). For example, the feeder assembly comprises a hopper magazine configured to store contact tips for a welding torch so that one contact tip is on top of another contact tip in their horizontal directions and to release each of the contact tips in the horizontal direction. The nozzle cleaning assembly may comprise a brush for cleaning the inner wall of the contact tip and a universal joint for off-centered rotation of the brush head.
US12162101B2 Welding current source
A welding current source for supplying an arc welding torch with electric current and electric voltage for carrying out an arc welding method, wherein the arc welding current source is provided with a housing in which a current transformer device is provided for processing electric current and voltage fed into the welding current source for suitability in an arc welding method, wherein furthermore two pole contact devices are provided on the housing of the welding current source, each of which protrudes out of the housing along a respective longitudinal axis and is provided with connecting means for receiving a welding current cable. The aim is to provide a possibility that collisions with welding current cables connected to a welding current source of the aforementioned type can be prevented as much as possible.
US12162100B2 Welding power supplies having dynamic current responses
Welding power supplies having dynamic current responses are disclosed. Example welding power supplies include: power conversion circuitry configured to convert supply power to welding current; a voltage sense circuit configured to measure an output voltage of the power conversion circuitry; and control circuitry configured to: in response to detecting that the output voltage has decreased below a lower voltage limit: control an increasing ramp rate of the welding current output by the power conversion circuitry; and in response to detecting that the output voltage has increased above the lower voltage limit, control a decreasing ramp rate of the welding current output by the power conversion circuitry.
US12162099B2 Method and apparatus for pulse welding
A method and apparatus for providing welding type power is disclosed. The output is cyclical, and is a controlled voltage output during the background and/or peak and a controlled current output during the transition up and/or down. During the controlled current portion the output is responsive to output voltage.
US12162097B2 Workpiece positioner assembly having compliance assemblies
A workpiece positioner assembly including a headstock apparatus having a motor and a headstock swing arm rotatably supported on the headstock apparatus. The headstock swing arm is configured to be rotated by the motor. The assembly includes a tailstock apparatus and a tailstock swing arm rotatably supported on the tailstock apparatus. The tailstock swing arm and the headstock swing arm are configured to support a workpiece. The assembly also includes a beam coupled to the headstock swing arm and to the tailstock swing arm to transmit rotation of the headstock swing arm to the tailstock swing arm, and a compliance assembly. The compliance assembly is provided between at least one of the headstock swing arm and the beam to enable relative movement between the headstock swing arm and the beam, and the tailstock swing arm and the beam to enable relative movement between the tailstock swing arm and the beam.
US12162092B2 Wide path welding, cladding, additive manufacturing
A welding or cladding apparatus in which one or more energy beam emitters are used to generate a wide beam spot transverse to a welding or cladding path, and one or more wide feeders feed wire to the spot to create a wide welding or cladding puddle.
US12162090B2 Method for selectively irradiating a material layer, method for providing a data set, device and computer program product
A method for selectively irradiating a material layer in additive production. The method includes: providing geometry data having geometry information of individual layers of a component that is to be produced by additive means, and defining an irradiation pattern for the layers by a computer-supported production method, wherein the irradiation pattern has a contour and a surface region in layers, wherein first contour vectors of the contour are specified for continuous irradiation operation and second contour vectors of the contour are specified for pulsed irradiation operation. A method for providing a data set, an additive production method, a corresponding device and a corresponding computer program product selectively irradiate a material layer in additive production.
US12162086B2 Welded joint manufacturing method, welded joint, tempering device, and welding apparatus
A welded joint manufacturing method includes: abutting a first electrode against a first steel sheet of a welded joint at a site A, which is a location at an outer side of a nugget in a sheet-plane direction in a plane running parallel to the first steel sheet; abutting a second electrode against a second steel sheet at a site B, which is a location at an outer side of the nugget in a sheet-plane direction in a plane running parallel to the first steel sheet of the welded joint, and positioned on an opposite side of the nugget from the site A; and passing a current through the welded joint between the first electrode and the second electrode.
US12162083B2 Cutter
A cutter includes: a cutter main body rotated; and cutting edges disposed on an outer periphery of a front of the cutter main body, wherein a mounting hole penetrating through the cutter main body is formed, an opening portion opening in a front of the cutter main body, a housing portion provided on a rear of the opening portion to house a head portion of a headed bolt, and a female thread portion are formed in the mounting hole, a mounting part including a male thread portion in an outer periphery is mounted to the female thread portion, the male thread portion screwable to the female thread portion, and a through hole having a smaller inner diameter than the head portion is formed in the mounting part.
US12162080B2 Electric rotary tool
A housing holding a stator has increased rigidity. A vibration driver drill includes a motor including a stator and a rotor rotatable relative to the stator, a gear case in front of the motor, a gear in the gear case to receive rotation of the rotor, an output shaft protruding frontward from the gear case to receive rotation from the gear, an integral cylindrical housing accommodating the motor and including a front portion with an opening and a rear portion closed, a gear case housing connected to the front portion of the integral cylindrical housing and including a right part and a left part and holding the gear case, and a grip housing extending downward from the gear case housing.
US12162078B2 Machine tool
A machine tool comprising: a first spindle; a second spindle provided on a rear headstock to face the first spindle; a barstock supply unit for supplying an elongate rod to the first spindle; and a processing means including a tool for processing the barstock, characterized in that the machine tool further comprises: a workpiece clamp device provided on the rear headstock and adapted to grip a second material comprised of the barstock that has been removed from the first spindle as an old material; and a joining means for joining opposite end portions of the second material gripped by the workpiece clamp device and of a first material gripped by the first gripping means and comprised of a barstock newly supplied by the barstock supply unit, thereby to integrate the second material and the first material into a single barstock.
US12162077B2 Method of producing highly crystalline silver microparticles
The present invention is a method of producing highly crystalline silver microparticles by a reduction reaction, which comprises precipitating the silver microparticles by reacting a silver solution containing at least silver ions and a reducing agent solution containing at least a reducing agent by a continuous wet reduction method, wherein a reduction rate from the silver solution to the silver microparticles is 99% or more; an average primary particle diameter of the silver microparticles is 100 nm or more and 1,000 nm or less; and an average crystallite diameter relative to the average primary particle diameter of the silver microparticles is 80% or more. Even highly crystalline silver microparticles having 95% or more of the ratio (d/D) of the average crystallite diameter (d) relative to the average primary particle diameter (D), that is, silver microparticles in which almost all silver microparticles are single crystals, can be continuously produced by a liquid phase method, by the present invention.
US12162075B2 Door hinge and method of manufacturing same
A method of manufacturing a door hinge, which can improve productivity by applying both metal injection molding and additive manufacturing is disclosed. The method includes: preparing a first mixture of a first metal powder and a first binder, and a second mixture of a second metal powder and a second binder; molding the first mixture into a first body including a first connection member having a first pinhole; molding the first mixture into a second body including a second connection member having a second pinhole to communicate with the first pinhole; arranging the first body and the second body to align the first pinhole and the second pinhole along an axis to form a cavity; forming a pin member with the second mixture in the cavity by adding up droplets of the second mixture in the cavity; and sintering the first body, the second body, and the pin member.
US12162074B2 System and method for large-area pulsed laser melting of metallic powder in a laser powder bed fusion application
The present disclosure relates to systems and methods for performing large area laser powder bed fusion (LBPF) to form a plurality of layers of a 3D part in a layer-by-layer fashion using meltable powder particles. In one implementation the system makes use of a first light source, which may be a diode laser subsystem, for generating a first light pulse of a first duration. The first light is used to preheat a substrate underneath a new layer of powder particles, wherein the substrate is formed from a previously fused quantity of the powder particles. A second light source, which may be a pulse laser, generates a second light pulse subsequent to the first light pulse. The second light pulse has a second duration shorter than the first duration by a factor of at least about 10, and fully melts the new layer of powder particles in addition to the substrate, to achieve a smooth printed layer. The wavelength of the first light pulse also differs from a wavelength of the second light pulse.
US12162059B1 Precision roll bending method, system, and electronic equipment for cylinder with variable curvature section
Disclosed is a method, system, and electronic device for precision roll bending of cylinder with variable curvature section. The method first obtains process parameters of roll bending of a target cylinder, and then conducts roll bending rebound simulation of the cylinder based on the process parameters to determine influence factors of rebound compensation error. Then, multiple sets of different preset influence factor values are set to perform roll bending rebound simulation of different arc segments. This disclosure uses multiple simulations of the rebound caused by cylinder roll bending to determine the factors that affect the rebound compensation error and the magnitude of the rebound compensation error that may be caused by these factors. Finally, an expression for the rebound compensation error is obtained to correct the rebound compensation equation, eliminating the error caused by rebound compensation, and ensuring that the cylinder forming meets the expected accuracy requirements.
US12162058B2 Hydroforming of aluminum extrusions for automotive battery tray structures
A structural component for a vehicle may include an extrusion that is extruded into a first state and then expanded into a second state. The extrusion in the first state has a reduced size relative to a desired final size. The extrusion in the first state is placed within a die that defines the desired final size. Pressurized water is distributed within internal cells of the extrusion in the first state such that the walls defining the internal cells are expanded into engagement with the surface of the die, thereby creating surface features or sealing interfaces with tight tolerances. The relative shape of the die and the extrusion in the first state defines an open space therebetween, into which the extrusion may expand to define the final shape. Some of the internal cells may be plugged such that they are not provided with pressurized water.
US12162057B2 Method for manufacturing hot-press-formed article, and hot-press-formed article
This manufacturing method of a hot press-formed article includes a heating step of heating an Al-plated steel sheet and a forming step of obtaining a hot press-formed article using a die after the heating step, the Al-plated steel sheet has a base steel sheet, an Al plating layer, and a coating layer, the coating layer is a metal layer containing at least one metal of Mg, Ca, V, Ti, and Zn, a metal oxide layer containing an oxide of one or more of Mg, Ca, V, Ti, and Zn, or a mixed layer including the metal layer and the metal oxide layer, the die has a hard layer on a surface, HVDie that is a surface hardness of the die at a position of the hard layer is HV1500 or more and HV3800 or less, and a temperature Tm of the Al-plated steel sheet at a start of forming and an average movement velocity V of the die in the forming step satisfy 800−(HVDie/40)≤Tm≤850−(V/4)−(HVDie/100).
US12162053B2 Devices and techniques relating to landfill gas extraction
Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods.
US12162051B2 Disposal of high-level waste into deep salt formations
Systems, methods, processes, and/or steps for the long-term disposal of high-level nuclear and radioactive waste, along with other radioactive waste forms, is done within deep salt formation(s) of predetermined characteristics. Waste may be emplaced within a given deep salt formation and after emplacement, creep of that deep salt formation around the deposited waste may entirely entomb that emplaced waste safely for geologic time periods. To emplace the waste, wellbore(s) may be drilled from the Earth's terrestrial surface into the given deep salt formation and then either a mostly horizontal wellbore may be formed within the given deep salt formation and/or a human-made cavern may be formed down and within the given deep salt formation. After emplacement, creep of the deep salt formation will destroy the initial boundaries of the horizontal wellbore and/or of the human-made cavern. This creep sealing process may occur over relatively short time periods.
US12162048B2 Label peeling device and label peeling method
According to an embodiment, a label peeling device includes a container holding portion configured to hold a specimen container, and a cutter holder configured to detachably hold a cutter, to apply a blade of the cutter to a side surface of the specimen container held by the container holding portion with a label being attached to the side surface, and to move along an axial direction of the specimen container, thereby peeling the label attached to the side surface of the specimen container.
US12162045B2 Wafer wet cleaning system
The present disclosure describes a wafer cleaning process in which a drained cleaning solution, which is used to remove metal contaminants from the wafer, is sampled and analyzed to determine the concentration of metal ions in the solution. The wafer cleaning process includes dispensing, in a wafer cleaning station, a chemical solution on one or more waters; collecting the dispensed chemical solution; determining a concentration of contaminants in the chemical solution; in response to the concentration of the contaminants being greater than a baseline value, adjusting one or more parameters in the cleaning process; and in response to the concentration of the contaminants being equal to or less than the baseline value, transferring the one or more wafers out of the wafer cleaning station.
US12162034B2 Internal surface treatment device for hollow engine shaft and the like
A surface treatment device for applying a surface treatment to an inner surface of a hollow engine shaft extending longitudinally along a shaft axis and having an axial shaft length to be treated. The device includes a supply of a surface treatment agent and an elongated rod extending from a proximal end to a distal end with an applicator disposed at the distal end. The elongated rod is insertable inside the hollow engine shaft. An applicator is disposed at the distal end of the elongated rod and wetted with the surface treatment agent. The applicator is engageable with the inner surface of the hollow engine shaft for applying the surface treatment agent to the inner surface of the hollow engine shaft. A pair of markers are disposed on the elongated rod and axially spaced apart from one another at a first axial distance corresponding to the axial shaft length.
US12162032B2 Sprayers, dispensers, and methods for using the same
Dispensing systems (100) having wands (110) for distributing a spray away from a user include moveable wands (110), wands for locking actuation of the dispensing system (210), wands and dispensers providing gravity fed dispensing solutions (410) for battery-operated devices (500) and improved dispensers.
US12162029B2 Shielding jig
The present invention discloses a shielding jig which mainly comprises an adjustment unit, a positioning unit and a sealing unit. The adjustment unit is configured and engaged between the positioning unit and the sealing unit. Therefore, a first actuation surface of the adjustment unit matches with a second actuation surface of the sealing unit, resulting in expansion of the sealing unit. This expansion makes the shielding jig be able to shade and seal any workpiece.
US12162027B2 Liquid material application apparatus and liquid material application method
Object: A liquid material application apparatus and a liquid material application method are provided with which a liquid material can be discharged in a predetermined discharge amount per unit time regardless of a relative moving speed in a series of application works.Solution: The liquid material application apparatus includes a discharge head, a robot moving the discharge head relative to a workpiece, a movement control unit controlling relative movement of the discharge head and the workpiece, and a discharge control unit controlling an operation of discharging a liquid material from a discharge head, wherein the discharge control unit executes, in a switchable manner in accordance with an application program, first mode discharge control of changing a discharge amount of the liquid material, which is discharged from the discharge head per unit time, depending on a relative moving speed between the discharge head and the workpiece, and second mode discharge control of operating the discharge head to discharge the liquid material in a predetermined discharge amount per unit time regardless of the relative moving speed. The liquid material application method is implemented using the liquid material application apparatus.
US12162022B2 Process for recycling a bituminous waste product such as a bituminous waste membrane product
An object of the instant application is to provide a process of recycling a bituminous product such as a waste bituminous membrane product optionally containing reinforcement layers comprising grinding and melting steps.
US12162021B2 Apparatus for comminuting pourable feedstock and method for opening such an apparatus
A device for comminuting pourable feedstock as well as a method for opening a device of this type. The device includes a housing, which encloses a comminution chamber, in which a rotor rotating around a rotation axis is arranged, the rotor being equipped with rotor tools over its circumference. A sieve holder, whose sieve extends along a circumferential section of the rotor, is used to separate the sufficiently comminuted material. The feedstock supplied to the rotor via a material infeed is removed from the device via a material discharge after being sufficiently comminuted. To improve accessibility to the interior of the device, it is proposed that, to open the housing, the sieve holder is pivotable around a first pivot axis from a closed first position into an open second position and additionally around a second pivot axis into a third position.
US12162016B2 Apparatus and method for handling sample containers
A sample rack includes a housing that has multiple spaces or compartments each for receiving and retaining sample containers of various sizes. The sample rack includes dual hooks on the ends for engaging a sample rack handling system. Chamfers formed in the housing of the sample rack assist in placing and removing the sample rack from a sample rack handling system. The sample tube rack also includes a handle that extends upward from one end and includes gripping features. A groove and bar, incorporated into each sample rack, are able to selectively interlock with adjacent racks to assist in lifting multiple sample racks together.
US12162013B2 Cell sorter with pivotal scuppers
A compact sorting flow cytometer system is disclosed. The system includes a flow cell and a deflection unit in communication with the flow cell to receive charged drops and uncharged drops in a stream of a sample biological fluid. The deflection unit includes a case having a deflection cone and chamber, a tub with a drain, and a slot in a base. The deflection unit further includes electrostatic charge plates in the cone forming an electrostatic charge field; and first and second pivotal scuppers, and a center non-pivotal collector arranged along a shaft in the tub of the case. Uncharged drops pass the electrostatic charge field undeflected in a center stream path while charged drops are deflected away from it. The pivotal scuppers pivot between positions to direct charged drops into the tub for aspiration or to pass through the slot in the base for collection.
US12162010B2 Biological fluid filtration system
A biological fluid filtration system for scanning a biological fluid so as to filter potentially undesirable constituents from the biological fluid for therapeutic or diagnostic purposes. The biological fluid filtration system generally includes a fluid receiving device adapted to receive a biological fluid. A valve including an inlet, a first outlet, and a second outlet is fluidly connected to the fluid receiving device. The biological fluid within the fluid receiving device is scanned by a scanner to produce scanned data relating to the biological fluid. A control unit in communication with the scanner and the valve receives the scanned data and controls the valve based on the scanned data. The valve is controlled to direct the biological fluid through either the first or second outlet of the valve depending upon the constituents of the biological fluid identified by the control unit.
US12162009B2 Solid phase purification
The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is amenable to automation. In particular, the method of the present invention comprises a method of purification carried out by means of solid phase extraction (SPE) alone.
US12162002B1 Selective reduction of α,β-unsaturated ketone using electronically weakly coupled 4,4′-divinylazoarylene-bridged diruthenium catalyst bearing two Ru(CO)(3-methoxypyridin-2-olate)(PiPR3)2 moieties
A 4,4′-divinylazoarylene-bridged diruthenium catalyst bearing two Ru(CO)(3-methoxypyridin-2-olate)(PiPr3)2 moieties, its synthesis, and its use as a catalyst.
US12162000B1 Hydrogen production by red mud-supported nickel-based catalysts and methods of preparation thereof
A method for generating hydrogen (H2) includes introducing a H2-containing feed gas stream into a reactor containing a red mud-supported nickel (Ni-SRM) catalyst including Ni-SRM catalyst particles. The method further includes passing the H2-containing feed gas stream through the reactor to contact the H2-containing feed gas stream with the Ni-SRM catalyst particles at a temperature of 500° C. to 700° C. to form an activated Ni-SRM catalyst and terminating the introducing the H2-containing feed gas stream. The method further includes introducing and passing CH4-containing feed gas stream through the reactor to contact the CH4-containing feed gas stream with the activated Ni-SRM catalyst at a temperature of 600° C. to 1000° C. thereby converting at least a portion of the CH4 to carbon and H2.
US12161998B2 Catalytically active particulate filter
The present invention relates to a particulate filter for removing particles, carbon monoxide, hydrocarbons and nitrogen oxides from the exhaust gas from internal combustion engines operated with a stoichiometric air-fuel mixture. Two coatings Y and Z are located in the porous walls and are present from the first end of the wall-flow filter over the entire length L of the particulate filter. Both contain active alumina, at least one cerium-zirconium-rare earth metal mixed oxide and at least one platinum group metal.
US12161997B2 Aqueous methods for titanating a chromium/silica catalyst
Methods for synthesizing a water-soluble titanium-silicon complex are disclosed herein. The titanium-silicon complex can be utilized to produce titanated solid oxide supports and titanated chromium supported catalysts. The titanated chromium supported catalysts subsequently can be used to polymerize olefins to produce, for example, ethylene based homopolymer and copolymers.
US12161995B1 Preparation method for nanocomposite fiber membrane material based on bio-based liquefied formaldehyde resin
A preparation method for a nanocomposite fiber membrane material based on a bio-based liquefied formaldehyde resin is provided. A bio-based raw material is processed through a phenol/polyethylene glycol complex liquefaction process, followed by divalent alkali metal hydroxide high ortho-position induction synthesis resinification and modification with the polymer polyvinyl alcohol to create a spinnable precursor as PVA-BLF. Subsequently, a coaxial electrospinning device is utilized, where PVA-BLF serves as a core layer and a titanium dioxide dispersion is used as a shell layer, to fabricate a PVA-BLF/TiO2 nanocomposite fiber membrane material. The average diameter of the nanocomposite fiber membrane is 150-450 nm, and the specific surface area is 500-700 m2/g. The porosity exceeds 60%, and the fracture elongation ranges from 5.5% to 6.5%, demonstrating excellent filtration performance and excellent regeneration performance, which can be developed as adsorption materials for water and air purification.
US12161992B1 Method of absorbing oil with microporous thin film
Polypropylene (PP) and polyethylene (PE) blends derived from plastic waste streams and a method to prepare reusable oil sorbents. A method includes separating plastics of group-A from group-B using a float-sink technique, where group-A comprises various PP and PE materials, and group-B comprises polystyrene, polyethylene terephthalate, and polyvinyl chloride; dissolving the group-A plastics in a solvent; adding a cavity forming agent to the solution; applying the solution onto a solid substrate through spin-coating followed by controlled heating; and extracting the cavity forming agent, obtaining a thin film sorbent with swellable cavities for oil sorption. The film contains 400-800 swellable 3D cavities/cm2, each cavity capable of swelling 20-30 times the thickness of the film when contacted with oil. The method improves compatibility of PP-PE blends without using compatibilizers, resulting in high oil uptake capacity due to swellable cavities, and reusability of sorbent with an oil recovery of more than 98%.
US12161990B2 EMM-41 composition, methods of making and uses thereof
This disclosure relates to EMM-41 materials, methods for making it, and processes for its use. This disclosure also relates to the structure directing agents used in the methods for making the EMM-41 material as well as the synthesis method used to prepare such structure directing agents.
US12161988B2 Powder, method of producing powder and adsorption apparatus
The present invention provides that powder is mainly constituted from secondary particles of hydroxyapatite. The secondary particles are obtained by drying a slurry containing primary particles of hydroxyapatite and aggregates thereof and granulating the primary particles and the aggregates. A bulk density of the powder is 0.65 g/mL or more and a specific surface area of the secondary particles is 70 m2/g or more. The powder of the present invention has high strength and is capable of exhibiting superior adsorption capability when it is used for an adsorbent an adsorption apparatus has.
US12161985B2 Alcohol-based organogel as nanofluid medium
An organogel including a base fluid, cetyl alcohol, and a gelling agent provided in an amount to cause the fluid to change from a liquid state to a gelled state at temperatures below at least 25° C. A nanofluid including an organogel and a nanoparticle component which permits the nanofluid to change from a liquid state to a gelled state at temperatures below at least 25° C., the gelled state helping to maintain the nanoparticle component suspended throughout the base fluid; and a method for preparing a gelled nanofluid.
US12161983B2 Mixer with single-use liner conversion to top-mix operation
A method and system for converting a single-use liner lined bottom-mix mixing vessel to a single-use liner lined top-mix missing vessel. A bottom mount magnetic impeller drive is replaced by a top mounted impeller drive. A support frame is placed on an upper portion of the mixing vessel and has an articulated joint supporting a motor drive assembly. A top-mix single-use liner is inserted into the mixing vessel. An impeller drive shaft is inserted through a rotary hub seal in the liner to drive an internal impeller. The rotary hub seal is located by a hub lock assembly attached to the motor drive assembly.
US12161979B2 Antifouling polymer for reverse osmosis and membrane comprising same
The present invention provides a composite membrane suitable for liquid-liquid filtration/reverse osmosis. The invention also provides a copolymer useful in the composite membrane, the copolymer comprising an anchoring repeating unit and a foulant-repelling repeating unit, as well as methods for preparing the composite membrane and copolymers. In a preferred embodiment, a copolymer (P [SBMA-co-HEMA]) is synthesized via the free radical copolymerization of a zwitterionic monomer of sulfobetaine methacrylate (SBMA) and an anchoring monomer of hydroxyl ethyl methacrylate (HEMA).
US12161978B2 Composite semipermeable membrane
The present invention relates to a composite semipermeable membrane including: a support membrane; and a separation functional layer provided on the support membrane, in which the separation functional layer includes a thin membrane, the thin membrane has a fold structure including a plurality of protrusions having a height of 10 nm or more, and in the fold structure, a ratio (T100/T25) is less than 0.95, where T25 is a thickness of the thin membrane in a region of 0% to 25% of the height of the protrusion and T100 is a thickness of the thin membrane in a region of 50% to 100% of the height of the protrusion.
US12161977B2 Durable biofouling protection
Disclosed are devices, methods and/or systems for use in protecting items and/or structures that are exposed to, submerged and/or partially submerged in aquatic environments from contamination and/or fouling due to the incursion and/or colonization by specific types and/or kinds of biologic organisms and/or plants, including the protection from micro- and/or macro-fouling for extended periods of time of exposure to aquatic environments.
US12161971B2 Catalyst for direct NOx decomposition and a method for making and using the catalyst
Catalyst material comprising a ternary spinel mixed oxide for treatment of an exhaust gas stream via direct decomposition removal of NOx to N2 and O2. The low temperature (from about 400° C. to about 650° C.), direct decomposition is accomplished without the need of a reductant molecule. In one example, Mn may be incorporated into metal oxide, such as CuyCo3-yO4 spinel oxide, synthesized using co-precipitation techniques.
US12161965B2 Volume compensating device for adsorbent fill compensation in an evaporative emissions canister
A volume compensating device for adsorbent fill compensation in an evaporative emissions canister is provided. The device includes a planar base plate having first and second opposite surfaces. A plurality of legs extend away from the first surface of the base plate. The legs each include a terminal free end. A foot is formed at the terminal free end of each leg. An evaporative emissions canister including the volume compensating device is also provided. The evaporative emissions canister includes an adsorbent filled chamber and a void space separated from the adsorbent filled chamber by a partition. The volume compensating device is disposed in the void space. The second surface of the base plate engages the partition, the feet of the legs engage an inner surface of the void space, and the legs resiliently urge the partition towards the adsorbent filled chamber, thereby preventing the adsorbent from entering the void space.
US12161964B2 Cylindrical heating unit and exhaust gas processing device including the cylindrical heating unit
A cylindrical heating unit of an exhaust gas processing device is installed in a reactor. The cylindrical heating unit is provided with an exhaust gas introduction port provided in an insertion base part and a heated exhaust gas outlet provided at insertion end. The cylindrical heating unit includes a hollow cylinder, insulators, electric heaters, and holding members. The hollow cylinder has a double structure with an inner cylinder and an outer cylinder made of metal. A plurality of the insulators surround the inner cylinder and are provided at intervals from each other in a heater installation space between the inner cylinder and the outer cylinder. Electric heaters are mounted to the insulators. The holding members are attached to one of the inner cylinder and the outer cylinder or both and hold the insulators in the heater installation space.
US12161961B2 Liquid filter arrangement and methods
A filter cartridge includes a threaded sleeve having a seal holder recess and seal member. The filter cartridge is for removably threading onto a filter head that includes threads for connection to the filter cartridge by way of the threaded sleeve. The filter head includes a ramp that engages the seal member to form a seal. The force needed to make the seal is a torque of less than 10 N-m.
US12161956B2 Filter cartridge, filter assembly, and methods
A filter cartridge includes a tubular core movably oriented within an inner liner and having a projection having a flow passageway. The core is free-floating and movable between a first position, in which the core can move along a longitudinal axis of the core, and a sealed position, in which the core is sealed to an inner liner of the cartridge. In the sealed position, the flow passage through the projection can provide an air flow passage of air within an inner cavity to outside of the filter cartridge. Other arrangements include a filter cartridge with a free-floating core, which forms a fuel bypass between the core and a standpipe.
US12161953B2 Container-type apparatus with a suspended particle system for wastewater treatment
A container-type apparatus for wastewater treatment with a suspended particle system, including one or multiple biological reaction zones. The biological reaction zones can be facultative, anaerobic, anoxic, and aerobic and at least one of the biological reaction zones is a suspended particle system. Particles in the suspended particle system act as the carrier of microbiota and offer better conditions for them to grow. The apparatus adopts a box structure, such as a container type, which is convenient to move, flexible to assemble, and can be used multiple times. Based on actual requirements, this apparatus can also be a structure type. The suspended particle system can increase the concentration of microorganisms significantly, improve the ability to bear impact load, produce less sludge, and without sludge expansion.
US12161949B2 Bubble machine with adjustable blowing angle
A bubble machine with an adjustable blowing angle comprises a machine body, an air supply mechanism arranged inside the machine body, and a film forming mechanism, wherein the air supply mechanism comprises a double-shaft motor, a fan cover arranged outside the double-shaft motor, and the film forming mechanism comprises a rotary table, a plurality of bubble rings uniformly arranged on the circumference of the rotary table, and a liquid storage tank arranged below the rotary table; one output shaft of the double-shaft motor is provided with a fan blade, and the other output shaft of the double-shaft motor drives the rotary table to rotate after being decelerated by a gear box; the bubble rings are arranged along the normal of the rotary table, and the fan cover is provided with a rotatable air duct at the position of the air outlet; the bubble rings are arranged along the normal of the rotary table, and then the air flow is output to the bubble rings through the action of the air duct. The air flow is strong, the wind force is sufficient, the bubbling effect is good, and the angle of the air duct is adjustable, which is suitable for more practical scenes.
US12161943B2 System for reducing the consumption of an electronic die
The object of the present invention relates to an energy management system of hardware of an electronic RF die for the coordination of the electronic RF die with remote terminals (e.g., PC, tablet, smartphone, gaming console). The system for reducing the consumption of an electronic game die includes four different activation levels of the hardware components, such as the microcontroller and accelerometer. The system includes two different activation thresholds, which can be set and updated dynamically, and are detected by the accelerometer to activate the different hardware components and adjust the transition between operating modes. The system detects the active presence of remote terminals and, particularly, whether or not the data sent has been received. Further, the system dynamically adapts the parameters of the four operating modes and the two activation thresholds to the different use situations of the die, i.e., to different environmental and game conditions.
US12161942B2 Videogame telemetry data and game asset tracker for session recordings
Disclosed are issue tracking systems, troubleshooting techniques, and user interfaces for troubleshooting, which are associated with a user of a software application triggering the recording of a session. During the session, the user may narrate suggestions or problems for the application while they interact with the application in real-time, and a recording engine of the application may record various types of session data, such as the user's interaction, narration, telemetry data, call stack data, and so forth. The session data is automatically submitted to an issue tracking system to process a support ticket. The issue tracking system may provide a user interface enabling a developer to review a support ticket and any associated session data to quickly determine the relevant portion of the application data (e.g., underlying program code) that needs to be modified. The issue tracking system may also process session data to identify related tickets or recurring issues.
US12161941B2 Systems and methods for a network-based video game application
Embodiments of the systems and methods disclosed herein provide a game that includes at least two users that each have a preconfigured set of playable virtual entities. The users draw playable virtual entities from each of their respective sets of playable virtual entities, and can play the playable virtual entities in one or more battles to facilitate moving a virtual positional marker towards a goal or shooting a goal, wherein the battle procedures are based on a turn priority. Certain attributes are associated with the playable virtual entities so that playable virtual entity effects, OVR values, and salary values can affect which playable virtual entities are in a deck and how the playable virtual entities are affected by the location of the virtual positional marker and/or other playable virtual entities.
US12161937B2 Information processing device and video editing method
A ring buffer 136 records a game video provided by a running game software 110 together with time information. When an unlock condition of a trophy that is a virtual award is satisfied, a trophy processing section 124 gives a trophy to a user playing a game. A video acquiring section 140 reads, from the ring buffer 136, the video including the game image that is at a time when the unlock condition becomes satisfied, and records the video in a second recording section 160. A video processing section 152 carries out an editing process on the video recorded in the second recording section 160.
US12161935B2 Computer device with joystick
A user device has a touchscreen on which a joystick is displayed. The joystick has one or more input translation layers which modify the behaviour of the joystick to match the required game physics of a game entity.
US12161932B2 Combination ramp system for sports
A combination ramp system includes a first ramp, a second ramp, and a first connection assembly. The first ramp has a first inclined surface. The second ramp has a second inclined surface. The first connection assembly includes a first connecting member and a second connecting member. The first connecting member is provided with a first connecting portion and a first butting portion. The second connecting member is provided with a second connecting portion and a second butting portion connected to the first butting portion. The first connecting member has a first top surface adjacent to the first inclined surface. The second connecting member in the vertical direction has a second top surface adjacent to the second inclined surface.
US12161931B1 Wheel assembly apparatus
A wheel assembly apparatus is disclosed. In at least one embodiment, a wheel hub is coaxially positionable within a wheel. A first bearing and a laterally opposed second bearing are each positionable coaxially within the wheel hub, with an inwardly facing medial surface of the first bearing being laterally spaced apart from an opposing inwardly facing medial surface of the second bearing so as to form a bearing gap therebetween. A first outer spacer is positionable in contact with an outwardly facing lateral surface of the first bearing, and a second outer spacer is positionable in contact with an outwardly facing lateral surface of the second bearing. Accordingly, an axle is capable of extending coaxially through each of the first outer spacer, first bearing, second bearing, second outer spacer, wheel hub and wheel, thereby enabling the wheel to rotate about the axle.
US12161921B2 Composite putter head with high moment of inertia
A putter is described. The putter includes a composite putter head having a high moment of inertia. The putter also includes a putter head face connected to the composite putter head. The putter further includes a hosel for mounting to a putter shaft. The putter also includes a plurality of sole weights mounted in a sole of the composite putter head.
US12161919B2 Golf club heads with turbulators and methods to manufacture golf club heads with turbulators
A golf club head including a face defining a loft plane, a rear, and a crown, the crown having a turbulator comprising a plurality of ridges. Each ridge includes a front surface having a first end nearest the face, a second end nearest the ridge apex, and a rear surface nearest the rear portion of the club head. The turbulator is positioned in a forward two-fifths portion of the crown in a front end to a rear end direction. The ridge apex of each ridge is positioned within the first 50% of the ridge length.
US12161912B1 Therapeutic, rehabilitation, and strengthening device
The invention relates to a device used for physical therapy, rehabilitation, or strengthening of the hands, arms, wrists, shoulders, elbows, or fingers of a user. The device is a ball with a stem extending from a surface of the ball, and a rotatable member that is rotatably engaged with the stem. The physical therapy, rehabilitation, or strengthening exercises are performed when the user holds the ball in the user's hand while using the fingers of that hand to rotate the rotatable member on the stem.
US12161911B2 Exercise apparatus
An apparatus can include a base with a pair of horizontal beams and a pair of uprights. The apparatus can include a support arm that is pivotally connected to the base. The support arm can include a buttock pad. The apparatus can include a compressible linkage connected to the support arm. The apparatus can include a pair of foot ramps. The pair of foot ramps can each be positioned along a respective one of the horizontal beams. The pair of foot ramps can be configured to angle a user's foot relative to a surface.
US12161910B2 Abdominal exercise device
An abdominal exercise device includes a frame comprising top, middle, and bottom frame sections. The middle frame section has a curved shape for creating a teeter-totter movement during exercise. The device includes a headrest connected to the bottom frame section, a plurality of connectors for connecting elastic bands to the frame, and an elastic band connected to at least two connectors. The two ends of the elastic band are connected to two straps. The device creates the teeter-totter movement to exercise the abdominal muscles in response to a person lying down in supine position with the back of the head on the headrest and the feet in the two straps, the person applying a downward pressure with the feet to the straps to move the headrest from a resting position, and the person removing the downward pressure to allow the headrest to go back to the resting position.
US12161909B2 Exercising apparatus with a limb support, and method for determining the force acting on a limb support of an exercising apparatus
An exercising apparatus for exercising at least one limb, having a supporting frame and at least one crank which is arranged on a rotation shaft assigned to the supporting frame, and having at least one limb support which can be fastened to the at least one crank at different radial distances from the rotation shaft. A detector is provided for detecting the radial distance of the at least one limb support from the rotation shaft. The invention further relates to a limb support and to a method for determining the force acting on a limb support of an exercising apparatus.
US12161908B2 Exercise treadmill
A treadmill has a front or rear set of pulleys and a looped running belt. The pulleys rotate with the movement of the belt, e.g., when a user walks, jogs, or runs on the treadmill. The pulleys are mounted on a rotating roller tube so that the roller tube rotates with the pulleys. The roller tube is mounted on a stationary shaft using bearings on each side and a one-way device that allows the pulleys to rotate in one direction. The rotation direction corresponds to the movement of the top of the belt from the front to the rear of the treadmill. The one-way device prevents the pulleys from rotating in the opposite direction, preventing the top of the belt from moving from the rear of the treadmill to the front. The one-way device may be a sprag clutch. The treadmill may be a motor-less, curved treadmill.
US12161907B2 Electromechanical physical resistance device
The present invention describes an electromechanical exercise machine that simulates the inertia and weight of a mass in Earth's gravity field and allows a user to move said simulated mass in the primary degrees of freedom of a traditional barbell free-weight system, with or without the use of various accessories.
US12161906B2 Exercise bar
An exercise bar comprising a pair of axially aligned straight ends for holding weights. An outer pair of curved grips extends inward from said straight ends, and an inner pair of curved grips extending inward from said outer pair of curved grips such that a first pair of parallel grips are formed that are generally perpendicular to said straight ends. A central curved section joins said inner pair of curved grips such that a second pair of parallel grips are formed that are generally perpendicular to said straight ends.
US12161902B1 Adjustable body weight exercise rack
One embodiment of a steel adjustable body weight exercise rack consists of a left and right pair of vertical uprights that are attached opposite one another along a base consisting of two parallel base tubes. A lower and upper pair of horizontal bars are attached across each pair of vertical uprights. The horizontal bars adjust up-and-down along the vertical uprights, and the vertical uprights adjust side-to-side along the base tubes. Three dimensional adjustments to the improved body weight exercise device allow the user to manipulate their body with and across the horizontal bars to perform virtually unlimited variations of body weight exercises.
US12161899B2 Automated grid storage and retrieval system with passive fire prevention arrangement
An autonomous grid storage system (1) arranged in a warehouse space (12). The autonomous grid storage system is divided within the warehouse space, for example on a single floor of said space, into a plurality of sub grids (10a/10b) separated by fire walls (18). One or more bridges (14) pass through openings in the fire wall to allow bin handling vehicles (210/301) to traverse between the sub grids. The openings (20) are provided with closable fire door (22).
US12161898B2 Adjustable face mask assembly
A face mask assembly configured with a drop down feature and a method of manufacturing the same are provided. The face mask assembly includes a face mask component slidable along a length of at least a first strap. The face mask component includes a first dynamic strap engagement feature defining a slide portion and a locking portion to engage the first strap. The slide portion includes a smooth edge such that the face mask component is slidable along the length of the first strap while the first strap is positioned within the slide portion. The locking portion includes a sharp edge to provide frictional restriction to the first strap during operation such that face mask component is locked relative to the length of the first strap while the first strap is positioned within the locking portion. A corresponding method of manufacture is also provided.
US12161897B2 Height safety davit with fail-safe mechanism
A davit (10) for arresting the fall of a person working at heights or for material handling where lifting of overloaded material is prevented, has a mast (12), a fuse holder (14) at the top of mast, a fuse head (16) connected to the fuse holder and having sacrificial fuses (18) arranged in series thereon, a jib arm (20) connected to the fuse head, and a primary fall arrestor system (22) having an arresting load limit and mounted to a side of the mast if the davit is to be used for arresting the fall of a person (25) working at heights, and/or a primary lifting-overload prevention system having a working load limit and safety factors if the davit is to be used for material handling where lifting of overloaded material (78) is to be prevented. When excessive forces are being absorbed either by the primary fall arrestor system or by the primary lifting-overload prevention system, the fuse head rotates downwardly relative to the fuse holder, and causes the breaking of one or progressively more of the sacrificial fuses until enough fuses have been broken to absorb the excessive forces.
US12161889B2 Blood brain barrier (BBB)-selective antibodies and methods of use thereof to target agents to the BBB
The present invention provides antibodies or antigen binding fragments thereof including single chain variable fragment (scFv) antibodies that specifically bind to the blood brain barrier in vivo and methods of use.
US12161885B2 Delivery of radiation by column and generating a treatment plan therefor
An example method of treating a target using particle beam includes directing the particle beam along a path at least part-way through the target, and controlling an energy of the particle beam while the particle beam is directed along the path so that the particle beam treats at least interior portions of the target that are located along the path. While the particle beam is directed along the path, the particle beam delivers a dose of radiation to the target that exceeds one (1) Gray-per-second for a duration of less than five (5) seconds. A treatment plan may be generated to perform the method.
US12161883B2 Renovascular treatment device, system, and method for radiosurgically alleviating hypertension
A radiosurgical method for treating cardiorenal disease of a patient, the method including directing radiosurgery radiation from outside the patient towards one or more target treatment regions encompassing sympathetic ganglia of the patient so as to inhibit the cardiorenal disease. In an exemplary embodiment, the method further includes acquiring three dimensional planning image data encompassing the first and second renal arteries, planning an ionizing radiation treatment of first and second target regions using the three dimensional planning image data so as to mitigate the hypertension, the first and second target regions encompassing neural tissue of or proximate to the first and second renal arteries, respectively, and remodeling the target regions by directing the planned radiation from outside the body toward the target regions.
US12161879B2 Methods and apparatus for phototherapy
An implantable phototherapy device includes a power receiver element configured to receive power from an external power transmitter, a light delivery element powered by the power receiver, and configured to deliver phototherapy to a target treatment area, and a tether element is coupled to the light delivery element and the power receiver element. The tether element is configured to deliver power between the power receiver element and the light delivery element.
US12161878B1 Wearable device for bioresonance modulation of muscle temperature and blood oxygen levels
A wearable system is disclosed, which may include a housing containing a processor, a network interface, a temperature sensor, an optical sensor, and an electromagnetic frequency generator. The system may further include a band connected to the housing for securing it to a user. The processor may be configured to receive muscle temperature and blood oxygen level data from the sensors, transmit the data to a remote device via the network interface, receive a bioresonance modality instruction from the remote device, instruct the electromagnetic frequency generator to emit an electromagnetic bioresonance frequency based on the instruction, and transmit updated muscle temperature and blood oxygen level data to the remote device. The system may enable remote monitoring and control of bioresonance to encourage the user's bioresonance state.
US12161877B2 Multi-coil wireless power transfer assembly for wireless glaucoma therapy
Systems and methods for wireless stimulation of biological tissue (e.g. nerves, muscle tissue, etc.) and, in one exemplary implementation, to therapy for glaucoma based on the wireless administration of energy to the eye of a mammalian subject (e.g. human, rodent, etc.) to reduce an elevated intraocular pressure (IOP) involving the use of a multi-coil wireless power transfer assembly. The multi-coil wireless power transfer assembly may be used alone or in combination with a stimulation coil that can be implanted in the eye of a mammalian subject or within a contact lens worn by a mammalian subject.
US12161875B2 Wearable medical device for continuous heart monitoring with intermittent additional signal data provided via one or more touch-sensitive electrodes
A wearable medical device is provided for monitoring a cardiac condition of a patient, where the device is releasably mounted to the patient's chest and includes at least two skin-facing electrodes forming a first one or more ECG leads for ongoing monitoring of heart functioning and at least one touch electrode for intermittently obtaining additional circuit vectors for deriving additional metrics regarding the functioning of the patient's heart. Each touch electrode is configured to form an additional lead/vector that is a larger vector and/or separated by at least 15° from a corresponding first lead/vector formed from the first one or more ECG leads in a vector cardiogram representation of the first one or more ECG leads and the additional lead/vector.
US12161873B2 Header connection system for implantable medical device
In various examples, a header of an implantable device includes a first header portion and a second header portion at least partially disengageable from the first header portion. In a closed configuration, the first header portion is fully engaged with the second header portion, and in an open configuration, the first header portion is at least partially disengaged from the second header portion. At least one bore within the header is sized and shaped to accommodate a proximal end of a lead. The bore is split substantially longitudinally to form a first bore portion and a second bore portion. With the proximal end of the lead disposed within the bore and a positioning feature interacting with a lead feature, at least one lead contact aligns with at least one header contact to allow the at least one lead contact to electrically couple to the at least one header contact.
US12161872B2 Systems, methods, and apparatus for external cardiac pacing
Systems and methods for cardiac pacing during a procedure are disclosed and may include an external pulse generator (EPG) for connecting to a lead. A remote-control module (RCM) wirelessly connected to the EPG may include user inputs to control the EPG. A central processing unit (CPU) with a memory unit for storing code and a processor for executing the code may be included where the CPU is connected to the EPG and RCM. The code may control the EPG in response to user input from the RCM. The CPU may be disposed in the EPG or the RCM, or an interface module (IM) configured to communicate between an otherwise conventional EPG and the RCM. The executable code may perform a continuity test (CT) routine, a capture check (CC) routine, rapid pacing (RP) routine, and/or a back-up pacing (BP) routine, in response to user input from the RCM.
US12161870B2 Fitting algorithm for recruiting of neural targets in a spinal cord stimulator system
A fitting algorithm for a spinal cord stimulator is disclosed, which is preferably implemented in a clinician programmer having a graphical user interface. In one example, coupling parameters indicative of coupling to neural structures are determined for each electrode in an implanted electrode array. The user interface associates different pole configurations with different anatomical targets and with different measurement techniques (subjective or objective) to gauge the effectiveness of the pole configuration at different positions in the electrode array. The pole configuration, perhaps as modified by the coupling parameters, is then steered in the array, and effectiveness is measured along with a paresthesia threshold at each position. Using at least this data, the fitting algorithm can determine one or more candidate positions in the electrode array at which a therapeutic stimulation program can be centered.
US12161869B2 Treatment of disorders associated with inflammation
Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
US12161866B2 Skin care device providing micro current to a mask for promoting production of collagen and elastin
A skin care device formed to cover the left side and right side of a human head and applying a micro current to a mask, includes: a wearing portion extending from the left side of the head through the back side to the right side; and an applying portion formed at each of two ends of the wearing portion and applying the micro current to the mask, wherein the applying portion includes: a conductive portion in contact with the mask; a cover portion to which the conductive portion is coupled and which includes a printed circuit board (PCB) generating the current; and a connecting portion electrically connecting the PCB and the conductive portion to each other, the connecting portion being formed of a conductive spring in elastic contact with the conductive portion.
US12161865B2 Systems, methods and devices for peripheral neuromodulation
In some embodiments, systems and methods can include a wearable device with an electrically conductive skin interface that excites the underlying nerves from a transcutaneous surface stimulator. The device may be sized for a range of user sizes with stimulation electrodes positioned to target the appropriate nerves, such as the peroneal, femoral, saphenous and/or tibial nerves. The stimulation may include burst stimulation, and involve receiving an input relating to autonomic nervous system activity of the patient.
US12161862B2 Devices and methods for repairing damage to a tissue
An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.
US12161861B2 Therapy delivery devices and methods for non-damaging neural tissue conduction block
Devices and methods for blocking signal transmission through neural tissue. One step of a method includes placing a therapy delivery device into electrical communication with the neural tissue. The therapy delivery device includes an electrode contact having a high charge capacity material. A multi-phase direct current (DC) can be applied to the neural tissue without damaging the neural tissue. The multi-phase DC includes a cathodic DC phase and anodic DC phase that collectively produce a neural block and reduce the charge delivered by the therapy delivery device. The DC delivery can be combined with high frequency alternating current (HFAC) block to produce a system that provides effective, safe, long term block without inducing an onset response.
US12161856B2 Control device and method for a heart pump
A control device for a heart pump, comprising a device for establishing the end-diastolic filling pressure in a ventricle and a device for associating a delivery rate of the pump, in particular a pump speed or an electric pump capacity, with the established end-diastolic filling pressure. By taking into account the end-diastolic filling pressure, a robust operating option of the heart pump, similar to the physio-logical control, is created.
US12161854B2 Blood pumps
A blood flow assist system can include an impeller assembly including an impeller shaft and an impeller on the impeller shaft, a primary flow pathway disposed along an exterior surface of the impeller. The system can include a rotor assembly at a proximal portion of the impeller shaft. A secondary flow pathway can be disposed along a lumen of the impeller shaft. During operation of the blood flow assist system, blood can be pumped proximally along the primary flow pathway and the secondary flow pathway. The system can include a sleeve bearing distal the impeller. The system can include a drive unit having a distal end disposed distal a proximal end of the second impeller. The drive unit comprising a drive magnet and a drive bearing between the drive magnet and the impeller assembly.
US12161851B2 Combined medical device with sliding frontal attachment and retractable needle
A medical device having a frontal attachment and a connector housing having at least a body part of an associated medical apparatus, the frontal attachment slidably engaging the connector housing and having a forwardly projecting, rearwardly biased needle and a needle retraction assembly, and the connector housing having a needle retraction cavity laterally offset from the needle in a first position, the needle retraction cavity being selectively movable relative to the frontal attachment following use to reposition the needle retraction cavity into alignment with the needle to permit retraction.
US12161843B2 Automatic drug delivery device
An automatic drug delivery device, for dispensing a fluid medicament, includes: a longitudinal housing; a removable cap; a syringe assembly having a hollow syringe body and an injection needle; and a drive mechanism. The loaded drive mechanism is operatively coupled with a safety shield movable within the longitudinal housing. The safety shield is biased into a proximal position in which it protrudes out of the proximal end of the longitudinal housing in order to cover a needle tip of the injection needle. The safety shield is movable into a distal position in which the injection needle is exposed for injection. The device includes a feedback mechanism providing a visual feedback to the user indicating an actual state of operation. The feedback mechanism includes a visual indicator which appears in a transparent window on the distal end of the housing.
US12161838B2 Bent spring powered injector
A wearable pharmaceutical delivery device is disclosed including a compressed elastic power source and a cylindrical pharmaceutical reservoir. Optionally, the compressed power source is positioned along a bent path. Alternatively or additionally, the compressed power source may power discharge of the pharmaceutical. Alternatively or additionally, the compressed power source may power extension of an injection needle. In some embodiments, a tensile element may activate an indicator when delivery of the pharmaceutical is complete.
US12161837B2 Delivery device with noise reducing component
A delivery device for delivering a medication to a patient includes a catheter with a catheter insertion mechanism, a housing, and a base with a surface for supporting a pump mechanism. A noise dampening member in or on the device inhibits noise and vibrations from the pump mechanism from transferring through the base and housing. The noise dampening member can be an elastomer that is coated on or adhered to the base. The noise dampening member can be molded in or on the base in a suitable location to dampen noise produced by the mechanical component. The noise dampening member can be between the base and the mechanical component or spaced from the mechanical component. The noise dampening member can be molded in a recessed area formed in the base and can have a top face that is recessed, aligned with or project from the top face of the base.
US12161836B2 Flexible cannula and process
A flexible tubing for a cannula has a hollow tubing body having a length dimension from a first end to a second end, and an outer diameter of no more than 0.9 mm. The tubing body has a section of enhanced flexibility of a greater flexibility than one or more other sections of the tubing body. The section of enhanced flexibility is spaced from the first end of the tubing body by a distance D, where D is within a range of 3.0 mm to 5.0 mm for a flexible tubing having a length of about 9.0 mm, and where D is within a range of 1.0 mm to 2.9 mm for a flexible tubing having a length of about 6.0 mm.
US12161835B2 Fluid mixing device
A fluid mixing device includes inlet ports in fluid communication with respective source containers, an inlet check valve, a mixing container in fluid communication with the inlet check valve, a discharge port in fluid communication with a target container, and a discharge check valve in fluid communication with the mixing container and the discharge port. Responsive to a negative pressure at the mixing container, fluid is drawn from the respective source containers through the inlet ports and through the inlet check valve and into the mixing container, while the discharge check valve precludes drawing of fluid from the target container. Responsive to a positive pressure at the mixing container, fluid is expelled from the mixing container through the discharge check valve and into the target container, while the inlet check valve precludes discharge of fluid from the mixing container to the inlet ports and the source containers.
US12161824B2 Multi-balloon dilation catheter
A method of dilating a target anatomical structure of an ear, a nose, or a throat of a patient includes inserting a distal end of a balloon catheter into the ear, the nose, or the throat. The balloon catheter includes a balloon assembly coaxially disposed along a proximally extending shaft. The balloon assembly includes at least first and second dilation balloons that at least partially overlap one another. The method also includes distally advancing the distal end until the balloon assembly is disposed in the target anatomical structure. The method also includes selectively dilating the target anatomical structure based on a diameter of the target anatomical structure by inflating the first dilation balloon to a first diameter or inflating the second dilation balloon to a second diameter that is greater than the first diameter. The second inflation lumen is not in fluid communication with the first inflation lumen.
US12161821B2 Devices and methods for fluid transfer through a placed peripheral intravenous catheter
An apparatus includes a catheter, an introducer, and an actuator. A distal end portion of the introducer is configured to be coupled to a peripheral intravenous line. The introducer defines an inner volume having a first portion that defines an axis parallel to and offset from an axis defined by a second portion. A first portion of the actuator is movably disposed in the first portion of the inner volume. A second portion of the actuator is movably disposed in the second portion of the inner volume and coupled to the catheter movably disposed in the second portion of the inner volume. The actuator moves the catheter between a first position, in which the catheter is disposed within the introducer, and a second position, in which at least a portion of the catheter is disposed within the peripheral intravenous line.
US12161820B2 Rapidly insertable central catheters including catheter assemblies and methods thereof
Rapidly insertable central catheters (“RICCs”) including catheter assemblies and methods thereof are disclosed. A RICC assembly can include a RICC, an introducer, and a coupling system configured to couple the RICC and the introducer together. A catheter tube of the RICC includes a side aperture in a distal-end portion of the catheter tube, which opens into an introducing lumen extending to a distal end of the RICC. The introducer includes an introducer needle extending through the distal end of the RICC when the RICC assembly is in at least a ready-to-deploy state thereof. The introducer is configured to be actuated with a single finger of a hand while holding a distal-end portion of the introducer between a thumb and another finger or fingers of the hand. The coupling system includes a distal coupler slidably attached to the catheter tube proximal of the side aperture.
US12161819B2 Catheter placement device including an extensible needle safety component
An insertion device for inserting a catheter into a patient's body is disclosed. In some embodiments, the insertion device combines needle insertion, guidewire advancement, catheter insertion, and needle shielding in a single device. In one embodiment, the insertion device comprises a housing including a hollow needle distally extending from the housing. At least a portion of the catheter is pre-disposed over the needle such that the catheter is disposed substantially external to the housing. A guidewire is included, as well as an advancement assembly that is configured to selectively advance the distal end of the guidewire out a distal opening of the needle in preparation for distal advancement of the catheter. The advancement assembly is further configured to enable distal catheter advancement before shielding the needle after use. The insertion device is configured to be grasped and used by a single hand of a user.
US12161817B2 Catheter with improved loop contraction and greater contraction displacement
A catheter with a variable circular loop is responsive to a contraction wire for increasing the coiling of the circular loop. The shape of the loop is supported by an elongated member, wherein a radially constrictive sleeve confines the contraction wire to extends immediately alongside the length of elongated member so as to improve uniformity and minimize misshaping of the loop during contraction.
US12161814B2 Medical devices having releasable coupling
This invention is directed to a medical device having a longitudinal axis, and including a handle and a catheter. The handle can include a body having a proximal end and a distal end, an actuator moveably coupled to the body, and a handle control member coupled to the actuator, wherein the actuator can be configured to move relative to the body to move the handle control member. The catheter can include a shaft having a proximal end and a distal end, wherein the proximal end of the shaft and the distal end of the body can be configured for releasable coupling. The catheter can also include a steering section located along the shaft and a catheter control member coupled to the steering section, wherein the catheter control member can be configured to move relative to the shaft to move the steering section relative to the longitudinal axis. The medical device can also include a securing member configured to move relative to at least one of the handle and the catheter to releasably couple the handle control member to the catheter control member.
US12161812B2 Breathing tube
Condensation or “rain-out” is a problem in breathing circuits and especially neonatal breathing circuits. The subject patent provides an improved breathing tube component for managing rain-out particularly in neonatal applications. In particular the breathing tube has a smooth inner bore, and an outer insulating layer containing stagnant gas and a heater wire.
US12161810B2 Respiratory apparatus and method for integrated oxygen generation and delivery
An integrated oxygen supply device that is configured to generate oxygen continuously and release the oxygen non-continuously is provided. In some embodiments, the oxygen generated by the integrated oxygen supply device is stored in a porous material with the integrated oxygen supply device. The delivery of the oxygen produced by integrated oxygen supply device to a patient, in those embodiments, is controlled. In some embodiments, the control of the delivering oxygen is according one or more breathing patterns. The breathing pattern(s) may or may not be a current breathing pattern of the patient. For example, in one embodiment, the breathing pattern is a predetermined breathing pattern with a specified inspiration period followed by a specified expiration period.
US12161807B2 Methods, systems and devices for non-invasive open ventilation with gas delivery nozzles within nasal pillows
A non-invasive ventilation system may include a nasal interface. The nasal interface may include a left outer tube with a distal end adapted to impinge a left nostril, at least one left opening in the left distal end in pneumatic communication with the left nostril, and a left proximal end of the left outer tube in fluid communication with ambient air. The left proximal end of the left outer tube may curve laterally away from a midline of a face. A right outer tube may be similarly provided. One or more left jet nozzles may direct ventilation gas into the left outer tube, and one or more right jet nozzles may direct ventilation gas into the right outer tube. The jet nozzles may be in fluid communication with the pressurized gas supply.
US12161806B2 Ventilator with automatic detection of a fault in a flow sensor, taking into account spontaneous breathing
The invention relates to a ventilator including a ventilation gas source, a ventilation tube assembly, a valve assembly, a flow sensor assembly comprising a distal flow sensor and a proximal flow sensor, a pressure sensor assembly for quantitatively detecting a gas pressure in the ventilation tube assembly a pressure-changing assembly for changing the gas pressure in the ventilation tube assembly and a control device which is designed at least to control the operation of the pressure-changing assembly on the basis of measurement signals from the proximal flow sensor, and on the basis of measurement signals from the proximal flow sensor and from the distal flow sensor, to infer the existence of a fault.
US12161805B2 System and method for providing enhanced pap metrics
A system for obtaining and providing enhanced PAP metrics of a patient's sleep period includes: a pressure support device for use in providing a flow of breathing gas to the patient; a processing unit; and a number of auxiliary devices in wireless communication with the processing unit. Each auxiliary device of the number of auxiliary devices is structured to detect and collect sleep-related data of the patient. The processing unit is programmed to: receive data obtained by a number of sensors of the pressure support device during operation of the pressure support device in providing the flow of breathing gas to the patient; receive supplemental data obtained by the number of auxiliary devices while the pressure support device is not providing the flow of breathing gas to the patient; and determine the enhanced PAP metrics of the sleep period of the patient utilizing the data and the supplemental data.
US12161803B2 Flow generator
A flow generator includes a housing, a blower structured to generate a flow of pressurized breathable air, and a suspension device to support the blower within the housing and provide a pressure seal between low and high pressure sides of the blower. The suspension device includes a bellows-like portion provided along the perimeter of the blower to absorb shock applied at least radially to the blower and one or more cones provided along upper and/or lower sides of the blower to absorb shock applied at least axially to the blower.
US12161799B2 Methods, systems and apparatus for paced breathing
Systems slow breathing with positive pressure therapy. In embodiments, a current interim breathing rate target is set, and periodically magnitude of a variable pressure waveform scaled to the current interim breathing rate target is increased if breathing rate is greater than the interim rate target to lengthen breath duration. The magnitude of the pressure increase may be a function of the difference between the interim rate target and the breathing rate. The interim rate target may be reduced in response to slowing breathing rate. The waveform cycles, inhalation to exhalation, when airflow decreases to a cycle threshold. Different interim rate targets have different cycle threshold functions that allow easier cycling as the interim rate targets decrease. Similarly, the waveform triggers, exhalation to inhalation, when airflow increases to a trigger threshold. Different interim rate targets have different trigger threshold functions that allow easier triggering as the interim rate targets decrease.
US12161798B2 Patient attachment detection in respiratory flow therapy systems
Systems and methods can determine whether a patient is attached to a respiratory device (such as to via a patient interface) by analyzing a flow parameter signal in the time domain. Additionally, the processes can classify the patient attachment status into one of the four categories: detached, attaching, attached, or detaching. The system can include a non-sealed patient interface, such as a nasal cannula in a nasal high flow therapy, or any other patient interfaces. Data of the patient's use of the respiratory system can provide therapy compliance and long-term trend of use information and/or progress in the patient's respiratory functions and/or other physiological functions.
US12161797B2 Dry powder medicament inhaler
Disclosed is a dry powder inhaler for delivering medicament from at least one blister pack, each blister pack having a plurality of spaced-apart blister pockets containing doses of the medicament. The inhaler comprises: a housing for accommodating unused and used portions of the at least one blister pack together with a dispensing mechanism for simultaneously opening at least two blister pockets at a time; and a manifold component through which air can be drawn in use of the inhaler. The manifold component comprises: first and second air inlet openings for receiving external air a first air outlet opening for providing the external air to a first opened blister pocket and a first medicament inlet opening for receiving air-entrained medicament from the first opened blister pocket, the first air outlet opening and the first medicament inlet opening being arranged side-by-side to enable simultaneous communication with the first opened blister pocket; a second air outlet opening for providing the external air to a second opened blister pocket and a second medicament inlet opening for receiving air-entrained medicament from the second opened blister pocket, the second air outlet opening and the second medicament inlet opening being arranged side-by-side to enable simultaneous communication with the second opened blister pocket; and a medicament outlet opening for delivery of the air-entrained medicament from the first and second opened blister pockets to the user, the first and second medicament inlet openings being fluidly connected to the medicament outlet opening by a medicament delivery conduit formed in the manifold component. The first and second air inlet openings are fluidly connected to the first and second air outlet openings by respective first and second air conduits in the manifold component, wherein the air conduits are separately provided so that the external air from each of the first and second air inlet openings does not mix with the external air from the other of the first and second air inlet openings before reaching the first and second opened blister pockets.
US12161794B2 Negative pressure device having oxygen scavenger and volume reduction
A negative pressure tissue treatment system useful for negative pressure therapy includes a drape, a gasket material, a reactor housing, a reactor, and any fluid connection(s). The drape covers the skin of a patient and maintains negative pressure under the drape. The gasket material cooperates with the drape to define an enclosed volume that is scaled by the gasket material. The reactor housing defines a closed chamber in fluid communication with the enclosed volume, and the reactor is disposed in the reactor housing. The reactor consumes oxygen from a system volume defined by the enclosed volume, closed chamber, and/or any fluid connection(s). As a result of the oxygen consumption, the system volume is reduced to between about 95% to about 80% of the initial system volume.
US12161792B2 Fluid collection apparatus
Fluid collection apparatuses and methods of use in negative pressure therapies are provided.
US12161788B2 Fluid circuits for sorbent cartridges with sensors
A system for measuring at least one fluid characteristic at various stages within a sorbent system that has a sorbent cartridge that has at least one material layer and at least one fluid passageway in at least one location in the sorbent system to provide a diverted sample stream from the various stages. At least one fluid characteristic of the diverted sample stream is measured.
US12161784B2 Systems and methods for volume reduction of blood products prior to transfusion
Methods and systems for transfusing reduced-volume blood components are disclosed. Previously collected blood components are introduced into a fluid circuit associated with an apparatus that further separates the component into a reduced volume component and supernatant. The reduced-volume blood component is transfused to the patient in need of the component without the risk of circulatory overload.
US12161782B2 Medical device and coating with bonding agent
The invention relates to a medical device for use in human vessels, in particular in the carotid artery, comprising: a self-expandable mesh structure which at least partially forms a curved wall, and has, in a radially compressed state, a cross-sectional diameter of not more than 2.5 mm, wherein the mesh structure is formed of at least one mesh structural element which has a height that is no more than 200 μm, in particular no more than 150 μm, preferably no more than 70 μm, where the height is measurable along a diameter of the mesh structure, and wherein the mesh structure is at least partially formed of a nickel titanium alloy and is at least partially coated in fibrin.
US12161780B2 Bone grafts including osteogenic stem cells, and methods relating to the same
Bone grafts and constructs including stem cells are provided. Example bone grafts include osteogenic stem cells seeded on a scaffold of osteoconductive cortico-cancellous chips and/or osteoinductive demineralized bone. Example constructs include extracellular matrix on a synthetic scaffold, in which the ECM is secreted from MSCs seeded onto the synthetic scaffold. Also provided are methods of making the present bone grafts and scaffolds. Further provided are methods of promoting bone healing and treating wound healing, by administering the present bone grafts and constructs to a mammal in need thereof. Also provided are kits that include the present bone grafts and/or constructs, or components thereof.
US12161775B2 Sterilization validation system and method
A sterilization validation system and method are disclosed that ensure sterilization of packaging materials that contain certain sterilized items that have been sterilized in a cleanroom environment. In accordance with the disclosed subject matter, garments (or other items or materials) that are sterilized inside autoclave or breather bags may be secured within tote liners that ensure sterility of the exterior of the breather bags containing the garments. Not only is it possible to ensure a recipient that the garment is sterile, but it is also possible to verify that the outside of the breather bag itself is also sterile, since the breather bag will remain sterilized inside the tote liner during shipping.
US12161774B2 Apparatus and method for disinfection of object
An apparatus is provided for disinfection of an object. The apparatus includes a rotatable platform, a reflective surface on the rotatable platform, and a transmissive base to carry the object. The apparatus acquires information associated with the object, which includes one of a size of the object, a relative position, or an angular orientation of the object with respect to an ultraviolet light source. The apparatus determines one or more control parameters based on the acquired information, which includes one of a distance between the transmissive base and the reflective surface, a time period, or a speed of rotation of the rotatable platform. Based on the one or more control parameters, the apparatus controls a movement of the transmissive base and the rotation of the rotatable platform, to cause the reflective surface to reflect an ultraviolet light emitted by the ultraviolet light source onto the object, via the transmissive base.
US12161773B2 Puff sterilization patch
The present invention relates to a puff sterilization patch and, particularly, to a puff sterilization patch which is manufactured in the form of a net or fabric by using yarns made of copper having sterilizing power and can be attached to a cosmetic container so as to sterilize a puff. To this end, the present invention comprises: a pad layer formed by weaving wefts and warps into a net, wherein the wefts mainly comprise yarns made of copper and are arranged at regular intervals, and the warps mainly comprise yarns made of a synthetic resin material and are arranged at regular intervals: and an adhesive layer provided on the underside surface of the pad layer.
US12161769B1 Mobile sterilization unit
A utilitarian highly maneuverable mobile disinfection unit for floors and other horizontal surfaces. A stable steerable self-powered cart is provided with an attached downward-projecting UVC light source. The light source has a parabolic reflector projecting the radiation downward and a peripheral floor brush doubling as a shield against escape of radiation.
US12161764B2 Composition and methods of treatment
The present invention relates nanoparticles formed of a polymer and an antifungal agent, wherein the polymer is selected from the group consisting of linear or branched or cyclic polymonoguanide/polyguanidine, polybiguanide, analogues or derivatives thereof, or mixtures thereof. The nanoparticles are particularly suited for the treatment of fungal nail or skin infections.
US12161761B2 Extended release multiparticulates of ranolazine
The present invention relates to an extended release multiparticulate composition comprising a plurality of discrete units, each discrete unit comprising ranolazine or a pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients. The said multiparticulate composition is sprinkled onto soft foods or liquids for oral administration. Further, the multiparticulate composition is bioequivalent to the marketed extended release tablet. It further relates to a process of preparation of said multiparticulate composition and method of treatment of patients suffering from angina by administering said composition.
US12161751B2 Steroidal compositions and method of making and use
Pharmaceutical compositions are described for the treatment of hypogonadism in humans. The compositions can include testosterone and triamcinolone along with carriers and/or adjunct ingredients. In some embodiments, the compositions can be made by mixing testosterone with triamcinolone to form an admixture, adding a binding agent to the admixture to form wet granules, drying the wet granules to form bulk granules, milling the bulk granules, and combining the milled granules with a coating agent.
US12161748B2 Topical formulations comprising tofacitinib
A topical formulation comprising (a) a therapeutically effective amount of tofacitinib; (b) at least one solvent; and (c) optionally one or more other pharmaceutically acceptable excipients is provided. Also provided is a method for treating and/or preventing autoimmune diseases in a subject administering said topical formulation.
US12161747B2 Gum and tooth treatment method with rinsing
A tooth paste composition comprising black cumin oil (Nigella sativa) and fluoride-doped bioactive glass, zinc oxide, and/or titanium oxide is disclosed.
US12161745B2 Peptides and compositions for use in cosmetics
A family of peptides which are able to increase synthesis of homeodomain protein Mohawk and useful as anti-aging agents and as rejuvenating agents.
US12161738B2 Deodorant compositions
A deodorant composition comprising a magnesium salt and an aqueous carrier, wherein the deodorant composition is substantially free of aluminum.
US12161730B2 Methods for making ultrasound contrast agents
Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.
US12161728B2 Reducing abnormal accumulation of TDP-43 in motor neurons in amyotrophic lateral sclerosis and/or frontotemporal dementia using a construct encoding cyclin F
Disclosed are compositions and methods for inhibiting abnormal protein accumulation, promoting motor neuron survival, inhibiting motor neuron degeneration and treating neurodegenerative conditions through expression of a nucleic acid sequence encoding cyclin F in motor neurons with an abnormally low level or activity of cyclin F. Also disclosed are methods for identifying agents that promote survival of motor neurons, inhibit degeneration of motor neurons and/or inhibit abnormal protein accumulation in motor neurons, identifying agents that are useful for treating neurodegenerative conditions, diagnosing neurodegenerative conditions, predicting the progression of neurodegenerative conditions, and monitoring the effectiveness of a therapy in reducing the progression of a neurodegenerative condition.
US12161726B2 Biomimetic vesicles and uses thereof
The present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. The disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. In a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. Also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
US12161724B2 Compositions and methods related to tumor activated antibodies targeting EGFR and effector cell antigens
Provided herein are multispecific antibodies for redirecting T cells to cancers, that rely on binding of one antigen interacting portion of the antibody to a tumor-associated antigen or marker, such as epidermal growth factor receptor (EGFR), while a second antigen interacting portion can bind to an effector cell antigen on a T cell, such as CD3, pharmaceutical compositions thereof, as well as nucleic acids, and methods for making and discovering the same.
US12161722B2 Bifunctional heterocyclic compound having BTK degradation function via ubiquitin proteasome pathway, and use thereof
The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.
US12161721B2 Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein
The present invention provides a number of process improvements related to the conjugation of capsular polysaccharides from Streptococcus pneumoniae to a carrier protein. These process are serotype specific and include acid hydrolysis, addition of sodium chloride to the reductive amination reaction, and addition of sucrose to dissolve polysaccharides. Polysaccharide-protein conjugates prepared using the processes of the invention can be included in multivalent pneumococcal conjugate vaccines.
US12161719B2 Method of enhancing the antimicrobial action of systemically administered antibiotics
Antibiotic for use in a method comprising systemically administering a photosensitive antibiotic to a subject having a microbial infection in a target tissue to provide a blood plasma concentration of the antibiotic in the subject; allowing the plasma or tissue concentration of the antibiotic increase to a predetermined level; and subjecting the target tissue to photodynamic therapy in order to increase the antimicrobial action of the antibiotic in the target tissue. With light activation the efficacy of the photosensitizer antibiotic can be enhanced, the spectrum of the microbial effect broadened and even an antiviral effect can be obtained. Generally, the present invention can be exploited when there is a need for enhancement of the local antimicrobial effect of antibiotics.
US12161717B2 CD38 modulating antibody agents
The present disclosure provides antibody sequences found in antibodies that bind to human CD38. In particular, the present disclosure provides sequences of anti-human CD38 antibodies. Antibodies and antigen-binding portions thereof including such sequences present features compatible with pharmaceutical manufacturing and development can be provided as fully human antibodies (e.g., fully human monoclonal antibodies or antigen-binding fragments) that can be useful for medical methods and compositions, in particular for treating cancer.
US12161715B2 EGFR targeted therapy
The present invention relates to compositions and methods for treatment of neurological disorders. In particular, the present invention relates to EGFR as a clinical target for treatment of neurological disorders.
US12161710B2 Malaria immunogen and methods for using same
An immunogen useful for treating malaria generally includes an immunogenic carrier and an antigenic malaria circumsporozoite protein (CSP) peptide that includes the peptide NPDPNANPNVDPNAN (amino acids 5-19 of SEQ ID NO:1) linked to the immunogenic carrier. The immunogen may be administered to a subject having or at risk of having malaria.
US12161707B2 Vaccines for Neisseria gonorrhoeae
Methods and compositions for immunizing a human subject against Neisseria gonorrhoeae.
US12161706B2 Cancer vaccines targeting BORIS and uses thereof
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen are disclosed. Methods of treating a subject with a BORIS-expressing tumor and methods of preventing a BORIS-expressing tumor are disclosed. A synthetic consensus BORIS antigen is disclosed.
US12161704B2 Immunosuppressive antigen-specific chimeric antigen receptor Treg cells for prevention and/or treatment of autoimmune and alloimmune disorders
Described herein are immunoresponsive cells which are useful for their preventive and therapeutic potential against autoimmune diseases and rejections of solid organ transplants.
US12161696B2 Methods of treating hemophilic arthropathy using chimeric clotting factors
The present disclosure provides methods treating reversible hemophilic arthropathy of a joint in a human having hemophilia comprising administering to the human an effective amount of a chimeric protein or composition comprising a clotting factor and an Fc region.
US12161694B2 Methods and compositions for regulating innate lymphoid cell inflammatory responses
Computational and functional analysis identified the neuropeptide receptor Nmur1 as selectively expressed on Type 2 innate lymphoid cells (ILC2s). While both IL-33 and IL-25 promote ILC activation in vivo, IL-33 induces robust ILC proliferation, whereas ILCs activated with IL-25 do not proliferate as robustly and up-regulate Nmur1 expression. Treatment with neuromedin U (NMU), the neuropeptide ligand of Nmur1, had little effect on its own. Co-administration of IL-25 with NMU, however, dramatically amplified allergic lung inflammation and induced the proliferation and expansion of specific ILC2 subsets, characterized by a molecular signature unique to pro-inflammatory ILC2s. The results demonstrate that Nmur1 signaling strongly modulates IL-25-mediated ILC2 responses, resulting in highly proliferative pro-inflammatory ILCs, and highlights the importance of neuro-immune crosstalk in allergic inflammatory responses at mucosal surfaces.
US12161692B2 SAP FC fusion proteins and methods of use
The present invention relates to SAP-Fc fusion proteins comprising one or more amino acid substitution, for example, C226S and/or C229S. In some aspects, the fusion protein comprises a structure represented by the following formula, from N-terminus to C-terminus, SAP-Fc1-L1-Fc2, wherein Fc1 is a first Fc domain sequence comprising hinge-CH2-CH3, L1 is a linker, and Fc2 is a second Fc domain sequence comprising hinge-CH2-CH3. The present invention also relates to methods of treating amyloid related diseases by administering said SAP-Fc fusion proteins to a subject in need thereof.
US12161691B2 Protein inhibitors of clostridium difficile toxin b
In an embodiment, the present disclosure pertains to a method of treating or preventing C. difficile infections. In some embodiments, the method includes administering an antitoxin to a subject in need thereof. In some embodiments, the antitoxin includes a designed ankyrin repeat protein (DARPin). In an additional embodiments, the present disclosure pertains to a composition including an antitoxin for treating or preventing C. difficile infections. In some embodiments, the anti-toxin includes a DARPin. In some embodiments, the anti-toxin is a monomeric or dimeric DARPin for the neutralization of Clostridium difficile toxin B (TcdB).
US12161689B2 Anti-infective formulations
The present disclosure provides pharmaceutical compositions for treating fungal and bacterial infections. The pharmaceutical compositions of the disclosure comprise a cationic surfactant, a chelating agent, and at least one solvent. The pharmaceutical compositions of the disclosure can be used to treat drug-sensitive or multi drug-resistant bacterial or fungal infections.
US12161687B2 Compositions targeting the interaction domain between p27KIP1 and Brk and methods of use thereof to inhibit p27 Y phosphorylation and cdk4 activity
Compositions and methods for the treatment of malignancy are disclosed.
US12161682B2 Topical composition and method of improving skin diseases and dermatitis using the same
The present invention provides a topical composition having a fermented product of lactic acid bacteria synbiotics as an active ingredient. The fermented product of lactic acid bacteria synbiotics is obtained by performing a fermenting step with lactic acid bacteria and a deactivating step on a fermenting substrate. The lactic acid bacteria are consisting of Lactobacillus salivarius subsp. salicinius AP-32, Bifidobacterium animalis subsp. lactis CP-9 and Lactobacillus acidophilus TYCA06. The fermenting substrate includes animal protein, plant protein and/or plant extracts. The aforementioned fermented product of lactic acid bacteria synbiotics can effectively inhibit the growth of Staphylococcus aureus and/or Propionibacterium acnes, and can be used in the topical composition.
US12161680B2 Methods of decreasing dysbiosis and restoring a microbiome
Provided herein are methods for decreasing dysbiosis, restoring the microbiome, and/or increasing recovery of a healthy microbiome (e.g. following a dysbiosis inducing event), by administering pharmaceutical compositions to a subject. Also provided are methods for protecting the microbiome of a subject and/or colonizing the microbiome of a subject by administering pharmaceutical compositions to the subject.
US12161675B2 Production method for culture supernatant preparation
To provide a culture supernatant preparation which has excellent biocompatibility and contains a large quantity of specific genes or proteins. A method for producing the culture supernatant preparation including: a first culturing step of culturing cells to a confluent state using a first medium; a second culturing step of culturing the cells using a second medium that is different from the first medium after the first culturing step; and a culture supernatant preparation obtaining step of obtaining the culture supernatant preparation including the second medium after the second culturing step, the second medium including a calcium ion and a buffering agent.
US12161672B2 Chimeric antigen receptor and methods of use thereof
The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided.
US12161671B2 Immune cells with DNMT3A gene modifications and methods related thereto
This disclosure relates to the genetic modification of DNMT3A gene in immune cells. In certain embodiments, the modified immune cells may be used in adoptive T cells therapies to enhance immune responses against cancer or chronic infections. In certain embodiments, the disclosure relates to deleting, changing, or inserting nucleotides within the DNMT3A gene in immune cells, e.g., human CD8 T cells, such that the DNMT3A gene product does not function for methylation. In certain embodiments, modification of the DNMT3A gene provides an improvement in antigen-specific T cells functions and/or an enhancement of the longevity of the cells.
US12161669B2 Compositions and methods for cell targeting therapies
The current disclosure provides polypeptide constructs and cells comprising CDR3 regions of γ9. δ2 or both, that selectively bind a J-configuration of CD277 on a target cell. The disclosure also provides pharmaceutical compositions with the disclosed polypeptides or cells and methods of using these compositions in the treatment of cancer.
US12161665B2 Cerium oxide nanocomplex and a composition for preventing or treating liver failure comprising the same
A cerium oxide nanocomplex, a composition containing the cerium oxide nanocomplex as an active ingredient, and their uses for preventing or treating inflammatory liver disease are disclosed. The present disclosure applies a biocompatible polymer composed of an optimal combination to significantly improve the biomedical stability, biosynthesis and efficiency of the production process of nanoparticles while maintaining the nanoparticles' excellent inhibitory activity against inflammation. In particular, the present disclosure may be applied as an effective therapeutic composition that effectively controls excessive immune response and inflammatory response and tissue injury in acute liver failure which is a serious condition of rapid loss of liver function that results in multiple organ failure and death.
US12161659B2 Compositions and methods for the delivery of nucleic acids
A compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, an aromatic group, polymer, a targeting group, or a detectable moiety; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.
US12161653B2 Treatment of submental fat
This disclosure relates to compositions, kits and methods for non-surgical reduction of localized subcutaneous fat such as that associated with a cosmetic fat accumulation. The methods employ compositions having specific concentrations of a salt of deoxycholic acid which provides a superior fat cell necrosis with modest adverse effects. Examples of localized subcutaneous fat are found in the submental area, in particular under the chin.
US12161650B2 Pharmaceutical compositions comprising a ryanodine receptor modulator and uses thereof
The present disclosure provides a modified-release pharmaceutical composition comprising 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)yl)methyl]benzoic acid hemifumarate, and a pharmaceutically-acceptable excipient. The present disclosure methods of treating conditions associated with RyRs, including, for example, cardiac disorder or disease, a musculoskeletal disorder or disease, cancer associated muscle weakness, malignant hyperthermia, and diabetes.
US12161649B2 Inhibitors of EGFR and methods of use thereof
The application relates to compounds, or pharmaceutically acceptable salts, hydrates, solvates, or stereoisomers thereof, which modulate the activity of EGFR, a pharmaceutical composition comprising said compounds, and methods of treating or preventing a disease in which EGFR plays a role.
US12161644B2 Combination therapy
Provided herein are methods of treating diseases, such as cancer, using a combination therapy. In certain embodiments, the methods comprise administering an effective amount of a phosphoinositide-3-kinase (PI3K) inhibitor and an effective amount of a PD-1 or PD-L1 inhibitor to a patient.
US12161643B2 Stable formulations of SHR0302
The disclosure relates to stable topical pharmaceutical compositions of SHR0302 (also known as ARQ-250). In certain embodiments, pharmaceutical compositions of SHR0302 having a pH of less than about 4.6 have improved stability and do not exhibit crystal formation of the API. In certain embodiments, pharmaceutical compositions of SHR0302 comprising about 20% to about 30% dimethyl sulfoxide (DMSO) have improved stability and do not exhibit crystal formation of the API. The improved formulations of SHR0302 can exhibit acceptable commercial product shelf life and do not exhibit loss of potency of the API after prolonged storage.
US12161642B2 Ferrochelatase inhibitors and methods of use
The invention relates to a method of treatment of a patient with a ferrochelatase inhibitor, or a pharmaceutically acceptable salt thereof, or a derivative thereof. Also, the invention relates to a method of treatment of a patient with a ferrochelatase inhibitor that is a triazolopyrimidinone, or a derivative thereof, or a pharmaceutically acceptable salt thereof.
US12161641B2 Treatments and prevention of opioid neonatal abstinence syndrome
Disclosed is a method for reducing or preventing fetal opioid dependence in a drug dependent or opioid tolerant pregnant subject. The method involves administering to the pregnant subject a composition comprising an opioid antagonist in an amount effective to reduce or prevent fetal opioid dependence, wherein the opioid antagonist a) is orally available or delivered systemically and reaches the circulation of the pregnant subject, b) is substantially excluded from the subject's brain by the blood brain barrier, and c) penetrates the placenta and enters the fetal brain. The method also includes administering the opioid antagonist to the neonate in increasing amounts to facilitate weaning the neonate from continued opioid maintenance.
US12161640B2 Opioid formulations
A depot precursor formulation comprising: a) a controlled-release matrix; b) at least oxygen containing organic solvent; c) at least 12% by weigh of at least one active agent selected from buprenorphine and salts thereof, calculated as buprenorphine free base. Corresponding depot compositions and methods of treatment in pain management, by opioid maintenance and related methods are provided.
US12161635B2 Compositions and methods of treating PIK3CA helical domain mutant cancers
A method of treating PIK3CA helical domain mutant cancer in a subject in need thereof includes administering to the subject therapeutically effective amounts of (i) an inhibitor of nuclear translocation of p85β and/or an EZH inhibitor in combination with (ii) a PI3K inhibitor.
US12161632B2 Compositions and methods of treating cardiac fibrosis with ifetroban
The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof.
US12161630B2 Methods to control infection using new generation small molecule growth inhibitors
Disclosed herein are methods of treating a subject with a bacterial infection, or preventing a bacterial infection, comprising administering to the subject an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. Also described are methods of inhibiting bacterial growth in a plant comprising contacting the plant with an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. The methods are effective against an array of bacterial pathogens in various animals and plants.
US12161628B2 Combination therapy
This disclosure provides a dosage regimen for co-administration of enzalutamide and a strong CYP3A4 inducer.
US12161616B2 Combination therapy comprising an omega-3 fatty acid, a folate species and a vitamin B12 species
The present invention provides a combined therapy comprising the use of one or more omega-3 fatty acids and one or more B vitamins and for treating cognitive impairment, such cognitive impairment disorders include, especially but not exclusively, Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD). The present invention also provides a treatment for individuals suffering from cognitive impairment disorders that occur as a result of brain or cerebral atrophy, the invention includes inter alia methods of treating and/or reducing progression of brain atrophy and pharmaceutical compositions and nutritional supplements therefor.
US12161615B2 Food supplement and composition for treating the metabolic syndrome
The invention provides a food supplement comprising chromium and the five amino acids leucine, isoleucine, valine, threonine and lysine, wherein leucine, isoleucine, valine, threonine and lysine are the only amino acids present in the food supplement, and wherein the sum content of the five amino acids is from 1.75 to 3.5 g per dose of the food supplement, and wherein the content of chromium is from 4.5 to 61 μg per dose of the food supplement. A food composition comprising the food supplement, as well as the five amino acids for use in a method of treating, controlling or preventing diseases or conditions related to the metabolic syndrome, treating or controlling diabetes, treating, controlling or preventing obesity, promoting satiety, promoting weight loss, or promoting maintenance of a healthy bodyweight, by lowering postprandial glycaemia, and preferably also by lowering postprandial insulin secretion, are also provided.
US12161611B2 Niclosamide formulations and methods of use
The present invention concerns compositions comprising at least one niclosamide compound, such as niclosamide or a pharmaceutically acceptable salt thereof, and at least one permeability enhancer, such as glycerol or dimethylpalmityl-ammonio propanesulfonate (PPS), and their use of such compositions as niclosamide agents. Advantageously, the niclosamide compound is capable of being transported across a Caco-2 cell membrane by at least 150% relative to the amount capable of being transported across the Caco-2 cell membrane in the absence of the permeability enhancer. Compositions, including oral dosage forms, and methods for delivering niclosamide compounds, such as for treatment or prevention of human coronavirus infections, are also provided.
US12161606B1 Network-connected containers having medication stored therein
Introduced here are containers designed to promote compliance with regimens for administering the medications stored therein. These containers have various features that allow them to be more easily managed by the individuals to whom the medications were prescribed. Some features improve the ease with which containers communicate with individuals. These features may enable information to be more easily input by individuals and/or output for individuals in a comprehensible manner. Other features improve the mechanical or electrical durability of containers. Such features may enable the containers to be used by individuals over the course of several days, weeks, or months without worrying about structural damage or loss of power.
US12161603B2 Vision improving device
An embodiment includes a vision training device with high training efficiency for the ciliary muscle including a housing having at least one eyepiece unit corresponding to an eye of a user, a display that displays a target image in front of a fixation axis of the user, a lens arranged between the eyepiece unit and the display unit, a movable unit capable of moving at least one of the display and the lens along the fixation axis, and a control unit that sets at least one training range within a movable range of the display and the lens and controls the movable unit such that at least one of the display and the lens is moved within the training range.
US12161601B2 Wheeleta
Wheeleta comprises a regular wheelchair to which, the front area has been altered to adapt a pair of crutches. Wheeleta crutch assembly includes the wedges, a sheath, a spear and the handle with under arm cushion area and the bar. It will attach the handle to the spear by lifting the button and introducing the bar into the spear until the previously established height is reached. The button is liberated and the height is fixed. The wedge is attached to the end of the spear and kept in place by a pivot with an open end with a rotating metal blade. The crutches could be out of way by twisting the spear in its own sheath and utilized by the user when rises to go out or entering the chair. The crutches could be removed from the sheath by lifting and pushing the crutch. The wedges also, could be completely removed from the spear by twisting a rotating metal blade at the end of the crutch pivot. The crutch handle with bar could be removed out of the spear and used to reach objects.
US12161600B2 Apparatus for pelvic floor muscle trigger point therapy
An apparatus for pelvic floor muscle trigger point therapy is disclosed. The apparatus comprises a wand to facilitate the release of one or more trigger points in a pelvic floor muscle of a patient. The wand comprises a central portion extending between a first end and a second end. The central portion includes a first bend and a second bend wherein the first bend is formed between a first end region and a first central region. The second bend is formed between the first central region and a second central region. The first end is configured to be vaginally insertable while the second end configured to be rectally insertable. A power source in electrical communication with one or more switches to selectively control a vibration element during use.
US12161599B1 Systems, methods, and devices for percussive massage therapy
A therapeutic system includes a device and an attachment for the device. The device includes an electrical power source and a mount. The attachment can be removably coupled to the mount. The therapeutic system also includes a first electrical connector including a socket and a second electrical connector including prongs configured to fit the socket. The attachment includes either the first or the second electrical connector, and the mount includes the other of the first or the second electrical connector. The electrical connector included by the mount is electrically connected to the power source.
US12161588B2 Application of electromagnetic radiation to the human iris
Rather than rely solely upon pupillary occlusion or tracking of eye movement to protect the fundus from accidental exposure to electromagnetic radiation, the present invention also utilizes an electromagnetic radiation pathway with a profile such that the energy density at the iris is greater than the energy density at the posterior portion of the eye. This disparity in energy density allows for efficacy at the anterior iris treatment site, without injury to the fundus.
US12161586B2 Systems for management of dry eye syndrome
In implementations of systems for management of dry eye syndrome, a palpebral fissure width is determined as a distance between a medial canthus and a lateral canthus of closed eyelids. An ideal eyelash length is generated based on the distance. Prostheses having the ideal eyelash length are attached to candidate eyelashes of an upper eyelid of the closed eyelids. The prostheses introduce a turbulence to airflow around a tear film which prevents the tear film from evaporating. Dry eye syndrome is managed by preventing the tear film from evaporating.
US12161577B2 Inflatable cervical collar neck system
A cervical collar system that includes a collar assembly that includes a wall member having an inner side and an outer side and a bladder member secured on the inner side of the wall member. The collar assembly includes an open position and a closed position and is configured to be received on the neck of a wearer. The cervical collar system also includes a first pump assembly in fluid communication with the bladder member.
US12161573B2 Stent and stent delivery for vascular surgery
A stent apparatus for use in surgical applications having a hollow tubular section with a proximal end and a distal end. The stent apparatus may also have a plurality of radially extending anchoring points centrally located between the proximal and distal ends. The stent being compressible can also include a sheath that is of a material that can be pulled away to remove it from the stent and deploy the stent and the plurality of radially extending anchoring points.
US12161572B2 Modular prosthesis system
The disclosure describes an adjustable modular prosthesis system comprising of repeating and interconnecting modular linkages. The modular linkages can be configured in a number of ways to form a network of modular linkages that comprise an adjustable custom socket around the limb of a user. The disclosed system further comprises a tensioning system that allows a user to control the socket's fit around their limb. The disclosed prosthesis system has a very low unique part count, may be mass-produced at low cost, and provides easy-to-use means of adjusting the shape and size of the socket to correspond with changes in a user's limb.
US12161571B2 Apparatus and method for protecting post-amputation residuum
An apparatus for protecting a post-amputation residuum comprises a shell defining a hollow interior cavity adapted for receiving and covering a distal portion of the residuum. The shell has an opening into the cavity at the distal end. A proximal portion of a compression sleeve is adapted to be disposed over at least a portion of the residuum. A free distal portion of the sleeve is configured to extend through the opening in the shell. The sleeve everts upon application of a longitudinal force to the distal portion of the sleeve in a proximal direction for folding over and covering the shell. The distal portion of the sleeve extends proximally of the shell to a position at least partially along the proximal portion of the sleeve for compressing the shell inwardly toward the residuum.
US12161570B2 Powered prosthetic knee with battery recharging during regeneration phase
Battery operated prostheses and systems having increased energy efficiency are disclosed. A prosthesis includes a first and second limb member coupled to an actuator to form a joint. The prosthesis further includes a rechargeable battery electrically coupled to the actuator. The actuator uses energy received from the rechargeable battery to actuate the first limb member relative to the second limb member. During at least a portion of a gait cycle of a wearer of the prosthesis, the actuator converts kinetic energy into first electrical energy that is greater than second electrical energy supplied to the actuator from the rechargeable battery. The prosthesis further includes a recharging circuit. The recharging circuit can receive at least a portion of the first electrical energy from the electric actuator and can supply some of the at least a portion of the first electrical energy to the rechargeable battery to recharge the rechargeable battery.
US12161569B2 Prosthetic hand system
A prosthetic hand structure including at least one mechanical finger having a metacarpal support and a proximal stiff link connected to the metacarpal support by a proximal cylindrical joint. The mechanical finger includes a transmission member connected to the proximal stiff link. The transmission member includes a worm screw integral to the proximal stiff link. The transmission member includes a flexible rack having a first end portion, pivotally connected to the metacarpal support, and a second end portion arranged to engage with the threaded profile of the worm screw at an engagement zone of the flexible rack. The structure also includes an actuator mounted to the mechanical finger and to actuate the worm screw, causing it to rotate about its rotation axis, in such a way that, when the actuator moves the worm screw, the mechanical finger extends or flexes.
US12161562B2 Method of forming and decorticating a void in a sacroiliac joint
A method for forming and abrading an implant void in a sacroiliac joint (“SI Joint”) without the use of a rotary cutting instrument. The method incorporates a multimodal abrading device having abrading surfaces on opposing sides, an open tip having a leading edge defining an enclosed oblong perimeter, and a cutting edge disposed at the leading edge of the open tip. The method includes the step of using the abrading head to cut bone tissue from the SI Joint at an insertion point while simultaneously using the abrading surfaces to decorticate the cortical bone at the insertion point.
US12161561B2 Intervertebral devices
An anterior lumbar interbody fusion device comprising a superior component, an inferior component, and a locking mechanism. The superior component bottom side and the inferior component top side oppose each other when these are received in the intervertebral space whereby their external sides abut against the respective vertebra, thereby coupling force between the latter. The components inter-engage with each other whereby they are constrained to move in an anterior-posterior direction relative to each other and resistance is presented to movement relative to each other in each of a direction of separation and a direction orthogonal to the anterior-posterior direction and to the direction of separation. The locking mechanism allows for relative movement of the components in the anterior-posterior direction which increases an extent of their overlap and presents resistance to movement of the at least one of the component in the anterior-posterior direction which decreases an extent of their overlap, for instance with a mechanism such as protrusions shaped to engage with set of recesses and sprung cantilever beams forming a ratchet mechanism. Optionally, the fusion device may comprise or lack a core component received between said superior and inferior components.
US12161558B2 Artificial vertebral endplates and associated methods
In a general aspect, an apparatus can include a plate configured for implantation in a body of a patient. The plate can include a plurality of pores and be configured for placement between a cancellous bone of a spinal vertebra and a corresponding cartilaginous endplate as a replacement for a bony endplate of the spinal vertebra.
US12161556B2 Internal pedicle insulator
A pedicle insulator implant is designed to protect the nerves and surrounding tissue from injury by pedicle screws or other surgical devices and instruments. The implant is configured to shield a fixture, reduce nerve root irritation, and diminish loosening of the fixture, when the fixture is implanted into the void of a target site. The implant includes features for stabilizing and securing the implant within the void at the target site. For example, in one embodiment, the implant includes one or more ridges and one or more teeth sections that stabilize the implant against rotational and extractive forces that could disturb the implant.
US12161554B2 Heart valve sealing devices and delivery devices therefor
A valve repair system for repairing a native valve of a patient includes a catheter and a valve repair device. The valve repair device is disposed in the catheter. The valve repair device comprises a compressible spacer and a pair of paddles. The pair of paddles are moveable between an open position and a closed position. The valve repair device can transition to a compressed configuration with the compressible spacer between the pair of paddles in the closed position.
US12161553B2 Steerable delivery system for replacement mitral valve and methods of use
Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. A delivery component can have a plurality of slots that provide for desired bending of the delivery component, particularly compound bending of the delivery component that can facilitate steering of the delivery component in three dimensions.
US12161549B2 Systems and methods for providing a graphical user interface for intraocular lens implantation planning
Systems and methods are presented for providing a graphical user interface (GUI) for assisting eye-care professionals in intraocular lens implantation planning in a two-stage process. During the first stage, first biometric data of a patient's eye is obtained. A first set of lens products comprising a first lens product is determined based on the first biometric data. A first grid is provided via the GUI to present the first set of lens products. During the second stage, second biometric data of the eye is obtained after an existing lens of the patient's eye is removed. A second set of lens products comprising a second lens product is determined based on the second biometric data. A second grid is provided via the GUI to present the second set of lens products and a difference between the first and second lens products.