Document Document Title
US11845962B2 Method for large-scale production of lentivirus by using GMP-level serum-free suspension cells
Provided is a method for large-scale production of lentivirus by using GMP-level serum-free suspension cells. Said method comprises the following steps: (a) providing a seed solution of packaged cells; (b) inoculating the seed solution in a first culture solution; (c) carrying out subculture of the packaged cells; (d) starting a liquid change operation when a liquid change trigger condition is met; (e) repeating steps (c) and (d) 1, 2 or 3 times; (f) starting a transfection operation when a transfection trigger condition is met; (g) optionally performing liquid change after transfection; (h) cultivating the transfected packaged cells; (i) starting harvesting and liquid change operations when a liquid change trigger condition is met; (j) repeating steps (h) and (i) 1, 2 or 3 times; (k) combining each of the recovered liquids; and (1) performing a purifying treatment. The culture solution used in each step is a serum-free cell culture solution.
US11845958B2 Genetically modified genes and cells, and methods of using same for silencing virus gene expression
Genetically modified CCNT1 and XPO1 genes encoding proteins that inhibit virus infection in cells. The genetically modified CCNT1 gene encodes a protein with a C261Y substitution with respect to the human CCNT1 protein. The genetically modified XPO1 gene encodes a protein with P411T, M412V, and/or F414S substitutions with respect to the human XPO1 protein. The genetically modified CCNT1 and XPO1 genes can be introduced in cells. The cells comprising the genetically modified CCNT1 and XPO1 genes can be introduced in a subject with a virus infection to treat the infection.
US11845957B2 Models of tauopathy
BANF1, PPP2CA, and ANKLE2 were identified as genes that promote tau aggregation when disrupted. Improved tauopathy models such as cells, tissues, or animals having mutations in or inhibition of expression of BANF1 and/or PPP2CA and/or ANKLE2 are provided. Methods of using such improved tauopathy models for assessing therapeutic candidates for the treatment of a tauopathy, methods of making the improved tauopathy models, and methods of accelerating or exacerbating tau aggregation in a tauopathy model are also provided.
US11845953B2 Method for converting nucleic acid sequence of cell specifically converting nucleic acid base of targeted DNA using cell endogenous DNA modifying enzyme, and molecular complex used therein
Provided is a method for altering a targeted site of a DNA in a cell, including a step of stimulating the cell with a factor inducing a DNA modifying enzyme endogenous to the cell, and bringing a complex of a nucleic acid sequence-recognizing module specifically binding to a target nucleotide sequence in a given DNA and a DNA modifying enzyme-binding module bonded to each other into contact with the DNA to convert one or more nucleotides in the targeted site to other one or more nucleotides or delete one or more nucleotides, or insert one or more nucleotides into the targeted site.
US11845951B2 Gene manipulation for treatment of retinal dysfunction disorder
The present invention relates to a composition for gene manipulation for treating or improving a retinal dysfunction disease or a method using the same. More particularly, the present invention relates to a composition for gene manipulation including a guide nucleic acid capable of targeting a retinal function-forming gene and a method of treating or improving a disease caused by retinal dysfunction by artificially manipulating and/or correcting a retinal function-forming gene using the same.
US11845948B2 Chromobacterium subtsugae genes
Disclosed herein are the nucleotide sequences of the Chromobacterium subtsugae genes. In addition, the amino acid sequences of proteins encoded by the C. subtsugae genes are provided. Nucleic acids, vectors and polypeptides comprising the aforementioned sequences are also provided. Homologues, functional fragments and conservative variants of the aforementioned sequences are also provided. Compositions having pesticidal, bioremedial and plant growth-promoting activities comprising C. subtsugae genes and proteins, and methods for the use of these compositions, are also provided.
US11845947B2 Plant resistant to Helminthosporium turcicum
The present invention provides an improved Helminthosporium turcicum-resistant plant, in particular a maize plant which comprises a polynucleotide with one or more resistance-conferring genes, for example on a truncated chromosome fragment from the accession Pepitilla, as well as a cell, a tissue, a part, grain and seeds thereof, an isolated polynucleotide which comprises one or more resistance-conferring genes against Helminthosporium turcicum, a vector, a transgenic plant cell and a transgenic plant containing this polynucleotide. Furthermore, the invention encompasses suitable markers and their use in introducing resistance or the transgene into a plant, as well as the identification of improved maize plants which comprise a truncated chromosome fragment.
US11845946B2 Tobacco plants exhibiting altered photosynthesis and methods of making and using
This disclosure provides tobacco plants that exhibit altered photosynthesis as well as methods of making and using such plants.
US11845943B2 Haploid inducer line for accelerated genome editing
Provided herein are materials and in planta methods for using haploid inducer lines containing a targeted endonuclease to generate transgenic or non-transgenic plants with targeted mutations and/or genomic modifications. Also provided herein.
US11845941B2 Plants comprising a low copy number of Ri genes
Described is a plant transformed with one or more genes originating from the Ri plasmid of Agrobacterium rhizogenes by infection with A. rhizogenes comprising the Ri plasmid, or being progeny of such a plant, said plant or progeny comprising, in the genome thereof, 1 to 5 copies said one or more genes originating from the Ri plasmid. Further, the use of such a plant or progeny thereof as ornamental plants, the use as field crop species, for food extracts, cosmetics, perfumes or as medicinal plants is disclosed. Further disclosed are methods for the preparation of such plants. Said plants display an intermediate height and/or with a higher content of metabolites without significant reduction of flower number or flowering time delay as compared to control plants void of Agrobacterium rhizogenes sequences.
US11845938B2 Aptamer compositions and the use thereof
Provided are aptamer compositions and their use for treating cancer.
US11845936B2 Modifications of mammalian cells using artificial micro-RNA to alter their properties and the compositions of their products
The present invention provides methods and compositions for stable genetic modification of cultured mammalian cells. The genetic modifications can be used to produce cultured mammalian cells for therapeutic or diagnostic purposes.
US11845927B2 Bioremediation using co-metabolism substrates
Certain disclosed embodiments concern a bioremediation composition comprising microbial cells, at least one co-metabolism substrate to induce selected enzyme production by the microbial cells, and a bead or gel encapsulating the microbial cells, such as bacterial or fungi cells, and the at least one co-metabolism substrate. For certain embodiments, the substrate is a slow release compound, such as an orthosilicate that hydrolyzes to produce an alcohol growth substrate. Embodiments of a method for using the composition to transform contaminants of concern also are disclosed.
US11845922B2 Cell incubator and a tool for use in a cell incubator
At least one tool removably mountable on a cell incubator mandrel or a cell incubator having at least one mandrel having an end portion, the at least one mandrel mounted on a movable transport for moving the at least one mandrel and at the least one tool removably mountable on the end portion of the at least one mandrel. The at least one tool is preferably electrically powered and controllable by signals applied to the at least one tool to perform at least one operation with respect to the incubation of cells.
US11845916B2 Burstable sporicidal cleaning wipe system containing stabilized hypochlorite
Sanitizing and disinfecting compositions with relatively low levels of free available chlorine, with good effectiveness against microbes, included in a burstable pouch of a system also including a plurality of initially undosed (e.g., dry) wipes in a resealable package thereof. The composition may include less than 0.5% by weight hypochlorite or other free available chlorine level, with a pH less than 12. The composition is long term stable in the pouch, but upon bursting of the pouch and dosing of the wipes, exhibits only short-term stability. Because of the low level of hypochlorite, the dosed wipes exhibit improved surface compatibility and negligible “bleach” odor, while providing at least a 3-log reduction in C. diff population within 10 minutes.
US11845912B2 Cleaning liquid composition and cleaning method using same
The present disclosure relates to a cleaning liquid composition and a cleaning method using the same. A polishing slurry composition according to an embodiment of the present disclosure includes: a chelating agent containing an organic salt; and an anionic surfactant.
US11845907B2 Carbon transfer film
Provided is a carbon transfer film excellent in wear suppression and friction reduction effects. A carbon transfer film 12 contains sp2-bonded carbon, wherein a ratio of zirconium calculated by elemental analysis of a surface by SEM-EDX measurement is 0.6 mass % or lower, and a thickness is less than 100 nm. A sliding member 1 includes a substrate 11 and a carbon transfer film 12 provided on at least one surface of the substrate 11, wherein the carbon transfer film 12 contains sp2-bonded carbon and has a thickness of less than 100 nm; and a ratio of zirconium calculated from elemental analysis the carbon transfer film 12 surface by SEM-EDX measurement of is 0.6 mass % or lower. A lubricant composition contains an organic dispersion medium as a lubricant base and nanodiamond particles nanodispersed in the organic dispersion medium, wherein a content ratio of zirconia is lower than 100 mass ppm.
US11845903B2 High yield jet fuel and chemicals from ozonolysis of triglycerides
A method for producing jet range hydrocarbons may include reacting at least a portion a fatty acid stream comprising C18:1 free fatty acid with ozone in an ozonolysis unit to form at least a C18:1 ozonide intermediate; introducing the C18:1 ozonide intermediate into a reactor, wherein at least a portion of the C18:1 ozonide intermediate is reacted with a reductive agent to produce oxidized products comprising azelaic acid and nonanoic acid; and introducing the oxidized products into a hydrotreating unit, wherein at least a portion of the oxidized products is hydrotreated to produce a paraffin product comprising nonane.
US11845901B1 Conversion of an aerosolized hydrocarbon stream to lower boiling point hydrocarbons
A method of converting a liquid hydrocarbon stream to lower boiling point hydrocarbons may include converting the liquid hydrocarbon stream to an aerosolized hydrocarbon particle stream, and subjecting the aerosolized hydrocarbon particle stream to reaction conditions. Reaction conditions may include a temperature from 25° C. to 1,000° C. and a pressure from 1 bar to 15 bar. The method may further include forming the lower boiling point hydrocarbons in the aerosolized hydrocarbon particle stream and separating the lower boiling point hydrocarbons from the aerosolized hydrocarbon particle stream. The lower boiling point hydrocarbons may comprise at least C2—C4 olefins.
US11845898B2 System and method for repairing a coke oven
A system and method for repairing a coke oven having an oven chamber formed from ceramic bricks. A representative system includes a insulated enclosure insertable into the oven chamber and includes removable insulated panels that define an interior area for workers to work in. The insulated enclosure is movable between an expanded configuration and a compact configuration and moving the enclosure to the expanded configuration will decrease the distance between the insulated enclosure and the walls of the oven chamber. Removing the panels exposes the ceramic bricks and allows workers within the interior area to access and the bricks and repair the oven chamber while the oven chamber is still hot. A loading apparatus lifts and inserts the insulated enclosure into the oven chamber. The insulated enclosure can be coupled to additional insulated enclosures to form an elongated interior area.
US11845894B1 Method of recovering hydrocarbon from a reservoir using date leaf carbon nanoparticles
A method of recovering a hydrocarbon from a reservoir is described. The method includes injecting an oil recovery formulation into the reservoir, and collecting the hydrocarbon from the reservoir. The oil recovery formulation includes date leaf particles selected from the group consisting of carboxylic acid functionalized date leaf particles and non-functionalized date leaf particles. The date leaf particles have an average particle size of 30 to 950 nanometers (nm). A method for preparing the carboxylic acid functionalized date leaf particles is also provided.
US11845884B2 Adhesive resin and adhesive composition for optical member including same
An adhesive resin and an adhesive composition for an optical member including the same is provided. The adhesive resin includes an acrylic copolymer formed by polymerizing a monomer mixture including a monomer represented by [Formula 1], a (meth)acrylic monomer having a cross-linkable functional group, and an alkyl (meth)acrylate-based monomer.
US11845882B2 Multilayer structure, resin composition for adhesive resin layer, and multilayer structure production method
A multilayer structure includes an adhesive resin layer provided between a thermoplastic resin layer and a gas barrier resin layer, wherein the adhesive resin layer is formed from a resin composition containing a polyolefin resin (A) containing at least one of a carboxyl group and an acid anhydride group, and a fatty acid zinc salt (B), wherein the fatty acid zinc salt (B) is present in the resin composition in a proportion of 40 to 250 ppm on a metal basis based on the amount of the adhesive resin layer.
US11845881B2 Cable and medical hollow tube
A cable includes a sheath, and a coating film covering a circumference of the sheath, the coating film adhering to the sheath. The coating film is formed from a rubber composition including a rubber component and fine particles. A static friction coefficient on a surface of the coating film is 0.5 or less. When the coating film is subjected to a testing such that a long fiber non-woven fabric including cotton linters including an alcohol for disinfection with a length of 50 mm along a wiping direction is brought contiguous to the surface of the coating film at a shearing stress of 2×10−3 MPa to 4×10−3 MPa, followed by wiping off the surface of the coating film at a speed of 80 times/min to 120 times/min and 20,000 repetitions thereof for a wiping direction length of 150 mm, a difference (an absolute value of a difference) between the static friction coefficients of the coating film before and after the testing is not greater than 0.1.
US11845879B2 Recording material
A recording material including a support having at least one colored surface and a layer of polymeric material is described. The layer including polymeric particles has a core/shell structure, and the particles are either (i) particles having an outermost polymer shell having a calculated Tg of from 40° C. to 80° C., or (ii) particles having an inner polymer shell having a calculated Tg of from 40° C. to 130° C. and an outer polymer shell having a calculated Tg of from −55° C. to 50° C. The calculated Tg of said outer polymer shell is lower than that of said inner polymer shell, the particles including, when dry, at least one void capable of providing opacity to said layer, and the colored surface has sufficient color density to be visibly contrasting to a surface of the subsequent layer including the polymeric particles disposed thereon.
US11845875B2 Glittery ink and image forming device
A glittery ink contains glittery pigment particles, resin particles, and an organic solvent, wherein the following relationships are satisfied: a≤c≤b and a
US11845873B2 Dye ink composition, dye ink for ink jet recording, and ink jet recording method
A dye ink composition includes: a dye represented by the general formula (I) as defined herein; water; a compound represented by the general formula (II) as defined herein; and a toning agent represented by the general formula (Cy-2) as defined herein.
US11845872B2 Dispersion composition, dispersion and ink composition, and method of producing the same
There are provided a dispersion composition containing: (A) from 85 to 99.89% by weight of a dispersant (except for the following (B) and (C)); (B) from 0.01 to 5% by weight of an acetylene glycol and/or an acetylene glycol ethoxylate; and (C) from 0.1 to 10% by weight of one or two or more types selected from polyoxy (ethylene-propylene) block polymers having a weight average molecular weight of from 1,500 to 20,000, a content of ethylene oxide of from 20 to 90% by weight, and a content of propylene oxide of from 10 to 80% by weight: a dispersion and an ink composition using the same, and a method of producing the same.
US11845870B2 Thin films printed with chalcogenide glass inks
A device formation method may include printing a chalcogenide glass ink onto a surface to form a chalcogenide glass layer, where the chalcogenide glass ink comprises chalcogenide glass and a fluid medium. The method may further include sintering the chalcogenide glass layer at a first temperature for a first duration. The method may also include annealing the chalcogenide glass layer at a second temperature for a second duration. A device may include a substrate and a printed chalcogenide glass layer on the substrate, where the printed chalcogenide glass layer includes annealed chalcogenide glass, and where the printed chalcogenide glass layer is free from cracks.
US11845866B2 Rubber composition for tire and studless tire
The present technology provide a rubber composition including: 100 parts by mass of a diene rubber, from 30 to 100 parts by mass of carbon black and/or a white filler, from 1 to 20 parts by mass of silicone-based microparticles that have an average particle size from 5 to 500 μm and that are three-dimensionally crosslinked, from 0.1 to 10 parts by mass of a nonionic surfactant, and from 1 to 20 parts by mass of thermally expanding microcapsules.
US11845863B2 Polyurethane dispersions and their use to produce coatings and adhesives
Aqueous polyurethane dispersions and coatings and heat-activatable adhesives made from the dispersions are disclosed. The dispersions include a polyurethane reaction product of a polyester polyol and a polyisocyanate. The polyester polyol comprises recurring units of at least one C2-C6 aliphatic diol, at least one aliphatic or cycloaliphatic C4-C10 dicarboxylic acid, and an aromatic diacid source, which can be recycled PET. The dispersion is formulated using 1 to 3 moles of an acid-functional diol per mole of polyester polyol. Dispersions for the adhesives are produced at NCO/OH molar ratios within the range of 0.90 to 0.98. The adhesives successfully bond a wide range of plastic and metal materials, often demonstrating substrate failure, even with steel. This contrasts with commercial adhesives such as EVA that exhibit only adhesive failure with the same substrates.
US11845861B2 Resin composition and molded article thereof
A resin composition, including a cellulose acylate (A), a polyester resin (B), and a cardanol composition (C) containing a cardanol-based compound having an epoxy group.
US11845856B2 Cellulose-reinforced polypropylene resin composite material, preparation method therefor and use thereof
The invention relates to a cellulose-reinforced polypropylene resin composite material, a preparation method therefor and use thereof. The cellulose-reinforced polypropylene resin composite material comprises, relative to the total weight of the composite material: 65 wt % to 85 wt % of polypropylene resin; 10 wt % to 20 wt % of a cellulose filler; and 1 wt % to 10 wt % of dyed rayon, wherein the color of the dyed rayon is different from that of the polypropylene resin. The cellulose-reinforced polypropylene resin composite material of the invention is environmentally friendly and simple to process, and has a simple molding process. The article prepared therefrom has excellent physical and chemical properties, uniform matte appearance and two-color effect.
US11845854B2 Polyethylene composition for films
A polyethylene composition for producing blown films, made from or containing an ethylene homopolymer or copolymer A) and an ethylene copolymer B) having a MIE value lower than the MIE value of A), the composition having the following features: 1) density from 0.948 to 0.960 g/cm3; 2) ratio MIF/MIP from 20 to 40; 3) MIF from 6 to less than 15 g/10 min.; 4) HMWcopo index from 0.5 to 3.5; 5) long-chain branching index, LCBI, equal to or lower than 0.82; 6) η0.02 of equal to or less than 150000.
US11845852B2 Low hysteresis sealant composition for self-sealing tire
This invention is based upon the unexpected finding that the reaction product of polyisobutylene and a silane can be incorporated into tire sealant formulations to greatly reduce the level of hysteresis exhibited by such sealant formulations which decreases the rolling resistance of the tire to improve fuel economy. This is made possible by the further unexpected fining that silanes will react with polyisobutylene by a reaction which is initiated with a peroxide. This invention more specifically discloses a sealant composition which is particularly useful in manufacturing self-sealing tires and which is comprised of (a) the reaction product of polyisobutylene and a silane; and (b) a reinforcing filler. The sealant compositions also contain a peroxide to facilitate partial degradation of the polyisobutylene rubber during the curing of the tire.
US11845850B2 Composition, laminate and window
The present disclosure provides a composition through which a laminate which is aesthetically excellent is formed by exhibiting a blue-based color, which is a general window color, and through which a laminate having high visible light transmittance and an excellent thermochromic property is formed while enabling mass production, and the present disclosure further provides a laminate formed through the above composition and a window including the laminate.
US11845849B2 Process for preparing dialkyl 1,4-cyclohexanedicarboxylates
A process prepares dialkyl 1,4-cyclohexanedicarboxylates by ring hydrogenation of the corresponding dialkyl terephthalate having a CO value of less than 0.3 mg KOH/g. The dialkyl 1,4-cyclohexanedicarboxylates thus produced can be used as plasticizers or as a component of a plasticizer composition for plastics, in particular PVC.
US11845848B2 Functionalized high-oleic soybean oil wax and emulsion for post-harvest treatment of fresh fruit
The present application is directed to a compound having the Formula (I): wherein R1, R2, and R3 are as described herein. The present application is also directed to a wax composition comprising a wax and a compound of Formula (I). Processes of making a wax composition and for coating a plant or plant part with the compound of Formula (I) are also described.
US11845845B2 Foam material particles based on long-chain polyamides
Foam particles that have a bulk density below 300 kg/m3 and are based on polyamides, including 85% to 100% by weight of at least one copolyamide obtainable by polymerizing the following components: (A) 15% to 84% by weight of at least one lactam, (B) 16% to 85% by weight of a monomer mixture (M) including the following components: (B1) at least one C32-C40 dimer acid and (B2) at least one C4-C12 diamine, wherein the monomer mixture (M) includes in the range from 45 to 55 mol % of component (B1) and in the range from 45 to 55 mol % of component (B2), based on the total molar amount of the monomer mixture (M), and the sum total of the components of (A) and (B) is 100% by weight, and processes for production thereof.
US11845843B2 Conductive silk fibroin material, and preparation method and use thereof
The present invention provides a method for preparing a conductive silk fibroin material, comprising the steps of: (1) preparation of a high-molecular-weight silk fibroin solution; (2) preparation of an insoluble silk fibroin material; (3) surface treatment of the silk fibroin material; (4) oxidation of the silk fibroin material; and (5) in-situ oxidative polymerization of 3,4-ethylenedioxythiophene on the surface of the graft-modified silk fibroin material. In the present invention, a conductive composite film grafted with 3,4-ethylenedioxythiophene on the surface is prepared, and the surface resistance is 100 to 5000 ohms. The preparation process is simple and mild, and the obtained conductive silk fibroin material can be used as a flexible electronic device, especially as a device for measuring human blood glucose level and heartbeat.
US11845842B2 Window cover film and flexible display panel including the same
The present invention relates to a new window cover film protecting a flexible display panel. Specifically, provided is a window cover film protecting a surface of a display device, the window cover film including a protective film formed on a base layer or a hard coating layer of a hard coating film having the base layer and the hard coating layer, and having no problem that the window cover film cannot be used as a display window cover film because a part of the protective film is not peeled off due to static electricity generated in the protective film, the base layer, or the hard coating layer when the protective film is peeled off, and the protective film remains on the base layer or a hard coating layer or the hard coating layer is partially or entirely peeled off.
US11845841B2 Polyester film for surface protection film of foldable display and use thereof
Provided are a foldable display that is excellent in mass production applicability, and that does not have image distortion that can appear in the folding portion after the display is repeatedly folded; and a mobile device equipped with such a foldable display. Provided are a polyester film for surface protection films and a hard coating film for surface protection films for the foldable display and mobile device. The polyester film is for foldable display surface protection films, wherein the polyester film is cut in sheet form, the polyester film has a thickness of 10 to 75 μm, the polyester film has an intrinsic viscosity of 0.55 to 0.65 dl/g, and the amount of rise of a cut plane on at least one side of one or more cut end portions is 35 μm or less. The hard coating film, the foldable display, and the mobile device use the polyester film for foldable display surface protection films.
US11845836B2 Cross-linked plastomers as a replacement for rubber
Articles comprising a polymer composition, wherein the polymer composition is obtainable by grafting an ethylene copolymer with comonomer units comprising hydrolysable silane groups, wherein the polymer composition shows high gel content and low compression set at −25° C. These articles have applications in automotive weather-stripping, such as sealing systems for doors, trunks and hoods.
US11845832B2 Method of making a PEEK-PEoEK copolymer and copolymer obtained from the method
A method of making a PEEK-PEoEK copolymer having RPEEK and RPEoEK repeat units in a molar ratio RPEEK/RPEoEK ranging from 95/5 to 45/55, the PEEK-PEoEK copolymer obtained from the method and the polymer composition including the PEEK-PEoEK copolymer, at least one reinforcing filler, at least one additive, or a combination thereof, shaped articles including the polymer composition, polymer-metal junctions including the polymer composition. Also described are methods of making the polymer composition, methods of making the shaped articles, and methods of making the polymer-metal junctions.
US11845826B2 Processes for preparing metallocene-based catalyst systems for the control of long chain branch content
Methods for preparing a metallocene-based catalyst composition that can impact the long chain branching of ethylene homopolymers and copolymers produced using the catalyst composition are described. The catalyst composition can be prepared by contacting a metallocene compound, a hydrocarbon solvent, and a first organoaluminum compound for a first period of time to form a metallocene solution, and then contacting the metallocene solution with an activator-support and a second organoaluminum compound for a second period of time to form the catalyst composition.
US11845815B2 Multiple reactor and multiple zone polyolefin polymerization
Apparatuses and processes that produce multimodal polyolefins, and in particular, polyethylene resins, are disclosed herein. This is accomplished by using two reactors in series, where one of the reactors is a multi-zone circulating reactor that can circulate polyolefin particles through two polymerization zones optionally having two different flow regimes so that the final multimodal polyolefin has improved product properties and improved product homogeneity.
US11845814B2 Ethylene polymerization processes and reactor systems for the production of multimodal polymers using combinations of a loop reactor and a fluidized bed reactor
Polymerization processes and reactor systems for producing multimodal ethylene polymers are disclosed in which at least one loop reactor and at least one fluidized bed reactor are utilized. Configurations include a loop reactor in series with a fluidized bed reactor and two loop reactors in series with a fluidized bed reactor.
US11845808B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
The present invention provides novel peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases.
US11845805B2 Bispecific antibody against CD3 and CD20 in combination therapy for treating diffuse large B-cell lymphoma
Provided are methods of clinical treatment of diffuse large B-cell lymphoma (DLBCL) (e.g., previously untreated, high-risk DLBCL) in human subjects using a bispecific antibody which binds to CD3 and CD20 in combination with standard of care regimen of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone).
US11845802B2 Combination therapy with a glucagon receptor (GCGR) antibody and an anti-CD3 antibody
The present disclosure provides methods comprising a glucagon receptor antagonist in combination with an immunotherapeutic agent for treatment of disease.
US11845799B2 Anti-Ly6G6D antibodies and methods of use
Provided herein are anti-Ly6G6D (lymphocyte antigen 6 complex, locus G61) antibodies and methods of using the same.
US11845797B2 Anti-TCR antibody molecules and uses thereof
The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.
US11845792B2 Epitope specific antibodies that bind cell surface GRP78 and their use for cancer detection
This application provides, inter alia, antibodies or antigen-binding fragments thereof, targeting cell surface GRP78 expressed on tumor cells, tumor endothelial cells, and tumor initiating cancer cells. These anti-GRP78 antibodies, or antigen-binding fragments thereof, have a high affinity for GRP78 and are less immunogenic compared to their unmodified parent antibodies in a given species, e.g., a human, and function to inhibit GRP78. Importantly, these isolated novel antibodies and antigen-binding fragments thereof, attenuate PI3K signaling and promote apoptosis in tumor cells, while leaving normal cells unaffected. The antibodies and antigen-binding fragments are useful for UPR-targeted cancer therapeutic treatments.
US11845791B2 Antibodies directed against GDF-15
The present disclosure is directed to human GDF-15-binding antibodies and antigen-binding fragments thereof. The antibodies and fragments can be used, for example, to detect human GDF-15 and/or in methods of treating cancer or body weight loss, including cachexia, associated with over-expression of human GDF-15.
US11845784B2 Means and methods for the treatment of angiogenesis-, fibrosis- and cancer-related diseases with protein oligomers comprising NC-1-Fc
The present invention pertains to a method for producing a protein oligomer comprising at least two, and preferably three heterodimeric human NC-I-Fc proteins, the method comprising: a) culturing a host cell expressing (i) a fusion protein comprising, from N- to C-terminus, human NC-1 from collagen 18 fused to human IgGI Fc with “knob” mutations, or human IgGI Fc with “knob” mutations fused to human NC-1 from collagen 18, and (ii) human IgGI Fc with “hole” mutations, under conditions which allow the formation of a protein oligomer comprising at least two, and preferably three heterodimeric human NC-1-Fc proteins, and wherein the fusion protein of (i) and the human IgGI Fc with “hole” mutations of (ii) are expressed in a ratio of 2:1 or higher, and b) obtaining the protein oligomer comprising at least two, and preferably three heterodimeric human NC-1-Fc proteins.
US11845782B2 Relaxin fusion polypeptides and uses thereof
The present invention relates to Relaxin fusion polypeptides, in particular to Relaxin 2 fusion polypeptides and uses thereof. Thus, the invention provides Relaxin fusion polypeptides, nucleic acid molecules, vectors, host cells, pharmaceutical compositions and kits comprising the same and uses of the same including methods of treatment. The polypeptides and compositions of the invention may be useful, in particular, in the treatment of cardiovascular diseases, for example for the treatment of heart failure.
US11845779B2 Mutant aerolysin and uses thereof
Aerolysin polypeptides and/or mutant aerolysin monomers include modified amino acid sequences that could have improved substrate analyte, such as (poly)nucleotide and peptide, improved reading properties such as enhanced substrate analyte capture and improved substrate analyte recognition and/or discrimination. Also, aerolysin pores may be derived from the mutant monomers as well as apparatuses and devices may include modified aerolysin polypeptides. Further, methods of using modified aerolysin proteins and pores derive therefrom may be used in characterizing and/or sequencing a polymeric molecule or may be for use as molecular sensors.
US11845778B2 Prefusion PIV F immunogens and their use
Embodiments of a recombinant human Parainfluenza Virus (hPIV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the hPIV F ectodomain trimer and methods of producing the hPIV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or inhibiting a hPIV infection in a subject by administering a effective amount of the recombinant hPIV F ectodomain trimer to the subject.
US11845777B2 Stabilized coronavirus spike (S) protein immunogens and related vaccines
The present invention provides redesigned soluble coronavirus S protein derived immunogens that are stabilized via specific modifications in the wildtype soluble S sequences. Also provided in the invention are nanoparticle vaccines that contain the redesigned soluble S immunogens displayed on self-assembling nanoparticles. Polynucleotide sequences encoding the redesigned immunogens and the nanoparticle vaccines are also provided in the invention. The invention further provides methods of using the vaccine compositions in various therapeutic applications, e.g., for preventing or treating coronaviral infections.
US11845773B2 Trehalose analogues
Described herein are trehalose analogues. Also described herein are methods of making the trehalose analogues and uses of the analogues. For example, the disclosed trehalose analogues may be useful in the detection of bacteria.
US11845772B2 Ribonucleic acid purification
Disclosed herein are methods for purifying RNA comprising poly A. Also disclosed herein are compositions such as surfaces and oligonucleotides for purifying RNA comprising polyA. Other embodiments are also disclosed. Commercially-available resins having polythymidine oligonucleotide ligands typically contain less than 30 thymidine (2′deoxy) residues and some commercial resin suppliers utilize a distribution of dT chain lengths, not of a discreet length.
US11845768B2 Polycyclic compound and organic light-emitting device including same
A compound of Chemical Formula 1, and an organic light emitting device including the same
US11845765B1 Anion binding agent lithium salts for battery electrolytes
A method for synthesizing a purified lithium (Li)+ anion binding agent (ABA-F)− salt and the corresponding Li+(ABA-F)− are disclosed. The method includes dissolving a boron-based acid in a polar solvent to form a solution. The solution is refluxed to form an anion binding agent. A stoichiometric amount of a small fluorinated salt, such as LiF, is added to the anion binding agent to form a mixture. The mixture is subsequently crystallized to obtain a substantially pure Li+(ABA-F)− salt. Example purified Li+(ABA-F)− salts include Ox-Li+(ABA-F), m-Li+(ABA-F), and BF3—Li+(ABA-F)−. These purified Li+(ABA-F)− salts provide the benefits of increased battery thermal safety without loss of electrochemical performance.
US11845764B2 Organic electroluminescent materials and devices
A compound including a first ligand LA of is disclosed. In the structure of Formula I, one of L1 and L2 is C, and the other is N; Y1 to Y14 are each C or N; at least two adjacent Y7, Y8, Y9, and Y10 are carbon atoms that are fused to a structure of Z1 and Z2 are each O, S, Se, NR, CRR′, or SiRR′; and each R, R′, RA, RB, RC, and RD is hydrogen or a substituent; and any two substituents may be joined or fused together to form a ring. In the compound, LA is complexed to a metal M by L1 and L2, and M has an atomic weight greater than 40. Organic light emitting devices and consumer products containing the compounds are also disclosed.
US11845761B2 Tricyclic pyridones and pyrimidones
Compounds with KRAS G12C inhibitory active are disclosed and methods of using the same to treat a cancer comprising a K-Ras G12C mutation.
US11845760B2 PRMT5 inhibitors
Described herein are novel PRMT5 inhibitors of Formula I and pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders. Compounds of Formula I have the following structure:
US11845759B2 Opioid compounds and uses thereof
This invention relates to novel opioid derivatives of Formula I: or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R3, R4 and Z are as defined herein in the disclosure. The invention also relates to the use of such compounds for the treatment or prevention of, for example, pain.
US11845758B2 Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms
The present invention relates to compounds of formula (I) or (II) pharmaceutically acceptable salts, solvates, tautomers, stereoisomers thereof, including enantiomers, diastereomers, racemic mixtures, mixtures of enantiomers, or combinations thereof, and pharmaceutical uses of the compounds.
US11845755B2 Compounds and methods for treatment of viral infections
Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
US11845754B2 Substituted pyrazolo[1,5-a]pyrimidines for modulating CDK9 activity
Inhibitors of CDK9 that are pyrazolo[1,5-a]pyrimidine derivatives and salts thereof, corresponding to formula (I):
US11845749B1 Substituted pyrido[4′,3′:5,6]pyrazino[1,2-a]indoles as anticancer agents
Pyrido[4′,3′:5,6]pyrazino[1,2-a]indole compounds are provided. The compounds exhibit inhibitory activity against CK2 enzyme and may be used as anticancer agents. The compounds have the following general formula I: where R1 represents aryl, heteroaryl, aminoaryl, aminoheteroaryl, aminoalkyl, aminocycloalkyl, aryloxy, heteroaryloxy, or alkoxy; and R2 and R3 represent hydrogen, carboxyl, ester, amide, halogen, alkyl, aryl, hydroxyl, alkoxy, aryloxy, aminoalkyl, aminocycloalkyl, aminoaryl, or aminoheteroaryl.
US11845748B2 Bicyclic pyridine N-oxide derivatives useful as a factor XIa inhibitors
The present invention is directed to bicyclic pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
US11845746B1 Ethyl 2-substituted-1-(substitutedbenzoyl)-7-methylpyrrolo[1,2-a]quinoline-3-carboxylate derivatives as anti-tubercular agents
Compounds for treating tuberculosis and, particularly, anti-tubercular compounds that are ethyl 2-substituted-1-(substitutedbenzoyl)-7-methylpyrrolo[1,2-a]quinoline-3-carboxylate derivatives and their use as anti-tubercular agents are provided.
US11845744B2 Methods and compositions for modulating splicing
Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, pharmaceutical compositions comprising the same, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.
US11845742B2 Therapeutic compounds and methods to treat infection
Disclosed herein are compounds of formula (I), or a salt thereof and compositions comprising compounds of formula I that exhibit antibacterial activities, when tested alone and/or in combination with a bacterial efflux pump inhibitor. Also disclosed are methods of treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I alone or in combination with the administration of a bacterial efflux pump inhibitor.
US11845741B2 Pilocarpine ionic liquids for treatment of glaucoma
The present disclosure provides pilocarpine ionic liquid analogs useful in the treatment of ophthalmological disorders such as glaucoma.
US11845737B2 Process for preparing a Cot inhibitor compound
Disclosed are syntheses of a Cot (cancer Osaka thyroid) inhibitor, which has the following formula:
US11845736B2 Prodrugs of MDMA, MDA, and derivatives thereof
The present disclosure provides prodrug compounds of MDMA, MDA, and derivatives thereof having an improved pharmacokinetic profile suitable for the treatment of various neurological diseases.
US11845735B2 Method for synthesizing (RS)-Warfarin
A method for synthesizing (RS)-Warfarin comprising preparing a liquid mixture, wherein the liquid mixture comprises trihexyltetradecylphosphonium bromide, methyl salicylate, acetyl chloride, benzaldehyde, and acetone. The method may further comprise incubating the liquid mixture at a temperature between 20° C. and 30° C. for a time duration between 26 and 34 minutes, and forming (RS)-Warfarin by adding water to the incubated liquid mixture with a volume ratio (water:incubated liquid mixture) between 1:1 and 1.5:1.
US11845733B2 Reagent for mass spectrometry
The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
US11845729B2 Processes and intermediates in the preparation of C5aR antagonists
Intermediates and methods are provided for the preparation of selected C5aR antagonist compounds.
US11845726B2 C4-carbonothioate-substituted tryptamine derivatives and methods of using
Disclosed are novel C4-carbonothioate-substituted tryptamine derivative compounds and pharmaceutical and recreational drug formulations containing the same. The pharmaceutical formulations may be used to treat brain neurological disorders.
US11845722B2 Deuterated compounds and uses thereof
The present invention provides for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.
US11845721B2 Processes and systems for separating carbon dioxide in the production of alkanes
A method for separating CO2 from C2 to C5 alkanes includes introducing a first stream including C2 to C5 alkanes and CO2 into a first separation zone, the first separation zone including a hydrocarbon solvent, and separating the first stream into a recycle stream and a second stream in the first separation zone. The recycle stream including CO2 and one or more of CO, H2, and CH4, and the second stream including C2 to C5 alkanes. The method further includes introducing the second stream into a second separation zone, and separating the second stream into a third stream and a fourth stream, wherein the third stream includes C2 alkanes and the fourth stream includes C3 to C5 alkanes.
US11845719B1 Light alkanes to transportation fuel
The present disclosure relates generally to processes and systems for producing liquid transportation fuels by converting a feed stream that comprises both isopentane and n-pentane, and optionally, some C6+ hydrocarbons. Isopentane and smaller hydrocarbons are separated to form a first fraction while n-pentane and larger components of the feed stock form a second fraction. Each fraction is then catalytically-activated in a separate reaction zone with a separate catalyst, where the conditions maintained in each zone maximize the conversion of each fraction to olefins and aromatics, while minimizing the production of C1-C4 light paraffins. In certain embodiments, the first fraction is activated at a lower temperature than the second fraction. Certain embodiments additionally comprise mixing at least a portion of the two effluents and contacting with either an oligomerization catalyst or alkylation catalyst to provide enhanced yields of upgraded hydrocarbon products that are suitable for use as a blend component of liquid transportation fuels or other value-added chemical products.
US11845715B2 Sulfonylureas and related compounds and use of same
The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
US11845714B2 Process for producing taurine
There is disclosed a process for producing taurine in a molar yield of at least 80% from alkali isethionate, alkali ditaurinate, or alkali tritaurinate by adding excess ammonia and at least of equal molar amount of an alkali hydroxide to a solution comprised of alkali ditaurinate, alkali tritaurinate, or their mixture and subjecting the solution to an ammonolysis to yield a solution comprised of alkali taurinate.
US11845712B2 Tail gas utilization for mixed alcohols production
It has been discovered that mixed-alcohol production can utilize the waste tail gas stream from the pressure-swing adsorption section of an industrial hydrogen plant. Some variations provide a process for producing mixed alcohols, comprising: obtaining a tail-gas stream from a methane-to-syngas unit (e.g., a steam methane reforming reactor); compressing the tail-gas stream; separating the tail-gas stream into at least a syngas stream, a CO2-rich stream, and a CH4-rich stream; introducing the syngas stream into a mixed-alcohol reactor operated at effective alcohol synthesis conditions in the presence of an alcohol-synthesis catalyst, thereby generated mixed alcohols; and purifying the mixed alcohols to generate a mixed-alcohol product. Other variations provide a process for producing clean syngas, comprising: obtaining a tail-gas stream from a methane-to-syngas unit; compressing the tail-gas stream; separating the tail-gas stream into at least a syngas stream, a CO2-rich stream, and a CH4-rich stream; and recovering a clean syngas product.
US11845708B2 Method for photocleavage of amide bonds
The present disclosure provides a method for photocleavage of an amide bond, the method has mild reaction conditions and can realize the cleavage of amide bonds by using light. The method comprises the following steps: subjecting 2,4-dinitrofluorobenzene to a reaction with an amino group of a substance represented by structural formula I with an α-amino acid at the end to produce a compound 1 represented by structural formula II; then under light irradiation, subjecting the compound 1 to a cleavage reaction of amide bond; Wherein, R1 is the side chain group of α-amino acid; R2 is: aryl, aliphatic hydrocarbon, —CH(R)—COOH or polypeptide.
US11845705B2 Processes integrating hydrocarbon cracking with metathesis for producing propene
Processes for producing olefins include passing a hydrocarbon feed to a hydrocarbon cracking unit that cracks the hydrocarbon feed to produce a cracker effluent, passing the cracker effluent to a cracker effluent separation system that separates the cracker effluent to produce at least a cracking C4 effluent including 1-butene, 1,3-butadiene, and isobutene, passing the cracking C4 effluent to an SHIU that contacts the cracking C4 effluent with hydrogen in the presence of a selective hydrogenation catalyst to produce a hydrogenation effluent having a 2-butenes concentration greater than or equal to the sum of the concentrations of 1-butene and isobutene. The processes include passing the hydrogenation effluent to a metathesis unit that contacts the hydrogenation effluent with a metathesis catalyst and a cracking catalyst downstream of the metathesis catalyst to produce a metathesis reaction effluent comprising at least propene.
US11845702B2 Method for fabricating porous ceramic heating body
A method for fabricating a porous ceramic heating body, and a method of fabricating a heating body. The method for fabricating includes, in sequence, mixing, ball-milling, defoaming, molding, and drying, pore-forming agent discharging, sintering, and electrode leading. The whole method is simple, and by using a box furnace to sinter the green body under an oxidizing atmosphere and normal pressure, the fabricated ceramic heating body is heated uniformly and the heating efficiency is high.
US11845701B2 EBC layer containing boron
The disclosure describes articles having coating systems configured to inhibit or prevent crystallization of TGO at the operating temperature of the article. An article includes a substrate defining a surface; a bond coat on the surface of the substrate; a coating layer that includes a boron dopant configured to inhibit crystallization of amorphous silicon dioxide thermally grown oxide on the bond coat at an operating temperature of the article. By inhibiting or preventing TGO crystallization, the described coating systems may increase a useable life of the component.
US11845698B2 Multilayer ceramic capacitor
A multilayer ceramic capacitor includes: a ceramic body in which dielectric layers and first and second internal electrodes are alternately stacked; and first and second external electrodes formed on an outer surface of the ceramic body and electrically connected to the first and second internal electrodes, respectively. In a microstructure of the dielectric layer, dielectric grains are divided by a dielectric grain size into sections each having an interval of 50 nm, respectively, a fraction of the dielectric grains in each of the sections within a range of 50 nm to 450 nm is within a range of 0.025 to 0.20, and a thickness of the dielectric layer is 0.8 μm or less.
US11845696B2 Dry construction composition wet-sprayable by means of a screw pump and containing a binder and a biosourced filler, and preparation and uses of such a composition
A dry construction composition is easily wet-sprayable by means of a screw pump, thus forming, after hardening, a durably mechanically resistant insulating material (λ<0.1 W·m−1·K−1). The composition contains: —A— at least one binder, itself including: —A1— at least one main binder containing lime and/or at least one alumina source and/or at least one calcium sulfate source, preferably at least one alumina source, —A2— at least one water-retaining agent, and —A3— preferably at least one surfactant; and —B— at least one biosourced filler, preferably of plant origin. The ratio B/A (liters/kg) is between 2 and 9. The composition is intended to be mixed with water in a water/binder ratio —A— of no lower than 0.8. Also disclosed is a wet composition, the preparation thereof, to the binder —A— taken in isolation, and to a method of spraying the composition onto a horizontal or vertical substrate or by molding.
US11845693B2 Twisted reinforcement fibers and method of making
A concrete structure formed of a mixture of concrete and a plurality of custom manufactured twisted steel micro-reinforcements (TSMRs). Each TSMR has a twist pitch of two or more twists per 25.4 mm applied along its longitudinal axis. The TSMRs are made from a common base stock and have the number of twists predetermined such that a concrete structure formed with at least 10 wt. % per unit volume less TSMRs than fibers in a conventional concrete structure exhibits the same or better performance than the conventional concrete structure in one or more of a stress, deflection, energy, or crack mouth opening (CMOD) properties as determined through defined standard tests. The performance requirement may be based on the actual test result and/or the consistency (coefficient of variation of the result).
US11845691B2 Heat-treated material having improved mechanical properties
A material including a transparent substrate coated with a stack of thin layers including at least one silver-based functional metallic layer and at least one zinc-based metallic layer. The zinc-based metallic layer is located above or below a silver-based functional metallic layer and separated from this silver-based functional metallic layer by at least one intermediate oxide layer based on one or more elements chosen from zinc, titanium, zirconium, tin, niobium, magnesium, hafnium and nickel.
US11845688B2 Glass ceramic with ion-conducting residual glass phase and process for the production thereof
The present disclosure relates to a lithium ion-conducting glass ceramic which comprises a residual glass phase that is also ion-conducting, a process for the production thereof as well as its use in a battery. The glass ceramic according to the present disclosure comprises a main crystal phase which is isostructural to the NaSICon crystal phase, wherein the composition can be described with the following formula: Li1+x−yMy5+Mx3+M2−x−y4+(PO4)3′, wherein x is greater than 0 and at most 1, as well as greater than y. Y may take values of between 0 and 1. Here, the following boundary condition has to be fulfilled: (1+x−y)>1. Here, M represents a cation with the valence of +3, +4 or +5. M3+ is selected from Al, Y, Sc or B, wherein at least Al as trivalent cation is present. Independently thereof, M4+ is selected from Ti, Si or Zr, wherein at least Ti as tetravalent cation is present. Independently thereof, M5+ is selected from Nb or Ta.
US11845686B2 Apparatus for forming glass tubes, a heating chamber and a process for the manufacture of an apparatus for forming glass tubes
An apparatus for forming glass tubes is provided. The apparatus includes a Danner-pipe, a heating device, and a heating chamber having the Danner-pipe and the heating device arranged therein. The Danner-pipe is inclined with respect to a horizontal plane by a Danner-angle. The heating device is inclined with respect to the horizontal plane by a heating-angle. The Danner-angle and/or the heating angle are in a range of 1° to 45°.
US11845684B1 Water conservancy construction sewage treatment mechanism
Water conservancy construction sewage treatment mechanism, including a support mounting cylinder, where a variable-diameter sedimentation cylinder is arranged at one end of the support mounting cylinder, one half of the cylinder wall of the support mounting cylinder is a thin wall and the other half is a thick wall, and the thin wall and the thick wall are disposed oppositely. The water conservancy construction sewage treatment mechanism also includes: a variable-diameter diversion cylinder, which is arranged on the thin wall at the other end of the support mounting cylinder; several displacement diversion modules, which are arranged on the thick wall of the support mounting cylinder and include guide displacement structures and combined diversion structures; and a magnetic attraction displacement adjusting structure, which is arranged on the outer side of the thick wall of the support mounting cylinder and is matched with the guide displacement structures and the combined diversion structures.
US11845680B2 Bio-electrochemical sensor, system and method for monitoring and controlling organic carbon levels in a wastewater treatment process
The present disclosure generally relates to a system for monitoring and/or controlling the delivery of one or more organic carbon compounds to a wastewater treatment system. The system comprises a bio-electrochemical sensor to monitor metabolic activity of a population of exo-electrogenic bacteria and provide an electrical output corresponding with the metabolic activity, the bio-electrochemical sensor comprising an electrode pair and a power source to deliver a voltage across the electrode pair, and an electrical output analyzer to analyze the electrical output and correlate the electrical output with a value representing the amount of the one or more organic carbon compounds in the wastewater treatment system. A method and sensor for monitoring and/or controlling the delivery of one or more organic carbon compounds to a wastewater treatment system are also provided.
US11845672B2 Alumina-based heterojunction material with abundant oxygen vacancies and preparation method thereof
Disclosed are an alumina-based heterojunction material with abundant oxygen vacancies and a preparation method thereof. The heterojunction material is composed of alumina with abundant oxygen vacancies and bismuth-rich bismuth oxychloride. The method includes mixing aluminum nitrate nonahydrate, bismuth nitrate pentahydrate, an ammonium salt and urea, each in certain amount, under stirring to obtain a mixture B, placing the mixture B in a muffle furnace, heating the mixture B and continuing the stirring to gradually melt the mixture B to form an ionic liquid B; and subjecting the ionic liquid B to a spontaneous combustion reaction in the muffle furnace to obtain a product B, and cooling the product B to room temperature to obtain the alumina-based heterojunction material with abundant oxygen vacancies.
US11845670B2 Task-specific ionic liquids for selective separation and recovery of rare earth elements
The present disclosure is directed to novel functionalized ionic liquids (ILs) that are used, for example, for enhanced recovery and separation of rare earth elements from aqueous solutions. The liquids and processes disclosed herein lead to greater separation efficiency, increased stability of separation materials, increased selectivity, and a reduced amount of waste materials.
US11845669B2 Efficient limestone processor with carbon capture capability
A system has conveyance segments arranged in series. Each segment has an infrared emitter directed towards a material bearing surface, and outlets of the segments are above inlets of subsequent segments. The segments are coupled to vibrators which are configured to convey a material from the inlet end to the outlet end of the segments. A system of this disclosure can be used to create lime or clinker with a substantial increase in efficiency, and without emitting any carbon dioxide to the atmosphere.
US11845667B2 Method for producing chlorosilanes
Chlorosilanes of the general formula HnSiCl4-n and/or HmCl6-mSi2, where n=1-4 and m=0-4, are produced in a fluidized bed reactor by reaction of a hydrogen chloride-containing reaction gas with a silicon contact mass granulation mixture composed of a coarse grain fraction and a fine grain fraction, wherein the average particle size of the fine grain fraction d50,fine is smaller than the average particle size of the coarse grain fraction d50,coarse.
US11845665B2 Preparation method of polyacrylonitrile-based three-dimensional macroporous carbon monolith
A preparation method of a polyacrylonitrile-based three-dimensional macroporous carbon monolith. The process route of the method includes the following steps: completely dissolving polyacrylonitrile in an organic solvent, then carrying out drying, cutting, hot-pressing and punching to obtain a foam precursor, next, preparing a polyacrylonitrile foam with a controllable pore structure by a supercritical carbon dioxide batch foaming method, and finally carrying out pre-oxidation and carbonization treatment to obtain the polyacrylonitrile-based three-dimensional macroporous carbon monolith. The preparation method of the polyacrylonitrile-based three-dimensional macroporous carbon monolith of the present invention is simple, easy to control, environmentally friendly and low in cost, thus, the present invention is conducive to large-scale production of the carbon monolith. The prepared polyacrylonitrile-based three-dimensional macroporous carbon monolith has the characteristics of uniform and controllable pore structure and good conductivity, and has a broad application prospect. The method has simple steps, convenient operation and high practicability.
US11845664B2 Capacitive deionization electrode
A process for the manufacturing of 3D reduced graphene oxide/Fe2O3 material includes the following steps: (i) putting in contact a graphene oxide (GO) water dispersion with an aqueous solution of iron(II) sulfate; (ii) hydrothermal treatment; and (iii) freezing the reaction product obtained in step (ii) at a temperature ≤−5° C.; and (iv) lyophilisation. A 3D reduced graphene oxide/Fe2O3 material is obtainable by the process and further relates to electrodes for CDI devices having the material. A method for removing ions from a fluid, like saline water, using the capacitive deionization device includes applying a voltage to the electrodes while supplying the fluid into the capacitive deionization device.
US11845657B2 Integrated method for producing sulphur dioxide quality suitable for a sulphuric acid process from calcium sulphate/phosphogypsum from phosphoric acid production
A process for producing sulfuric acid and cement clinker may use calcium sulfate that is formed as a solid by-product and separated off in phosphoric acid production in a reaction of raw phosphate with sulfuric acid to form phosphoric acid. The process comprises treating calcium sulfate separated from the phosphoric acid with an acid to obtain a suspension comprising purified calcium sulfate, separating the purified calcium sulfate in solid form from the liquid phase of the suspension, mixing the purified calcium sulfate with admixtures and reducing agents to obtain a raw meal mixture for cement clinker production, burning the raw meal mixture to obtain the cement clinker, with formation of sulfur dioxide as offgas, and subjecting the sulfur dioxide formed to offgas purification and feeding the sulfur dioxide as raw material to sulfuric acid production to produce the sulfuric acid. The sulfuric acid produced may be used as starting material in phosphoric acid production.
US11845655B2 Carbon nanotube dispersion and method for preparing the same
The present invention relates to a carbon nanotube dispersion including carbon nanotubes, a polymer dispersant containing an amine, a phenolic compound including two or more aromatic rings, and an aqueous solvent, wherein the polymer dispersant and the phenolic compound including two or more aromatic rings are included in a weight ratio of 100:1 to 100:90, and having low viscosity and a small change of viscosity over time.
US11845651B2 Spool of pocketed springs
A spool (100) of a linear string (110, 210, 310, 410) of pocketed springs is disclosed. The linear string of pocketed springs comprises springs (212, 312, 412) each provided in a textile pocket (214, 314, 414). The springs (212, 312, 412) comprise helically coiled steel wire springs. The textile pockets (214, 314, 414) are assembled to each other in linear direction. The linear string (110, 210, 310, 410) has a width of one textile pocket (214, 314, 414). The string (110, 210, 310, 410) of pocketed springs is present in the spool (100) spirally wound and in a compressed state such that the pocketed springs (212, 312, 412) can expand upon unwinding the string (110, 210, 310, 410) of pocketed springs from the spool (100).
US11845649B2 System and method for forming a foundation truss
A system and method for forming a foundation truss for a box spring or mattress foundation frame includes a first truss rail assembly station having a series of block feeders, a top rail hopper and a filler strip hopper that received stacks of truss components such as blocks, top rails and filler strips and feed such truss components into stacked registration. The stacked truss components are moved into engagement with a series of staplers that secure the filler strips, top rails and blocks together to form first truss rail portions, which are then fed to a second truss rail assembly station where a bottom rail is automatically applied thereto.
US11845647B2 Systems and methods for monitoring and controlling dispenser fluid refill
A counter mountable fluid dispenser includes a below deck reservoir for storing a fluid comprising at least one of a soap, an anti-bacterial cleanser, a disinfectant, and a lotion, an above deck spout including an outlet port in fluid communication with the reservoir for dispensing fluid stored in the reservoir and an external supply port connected with the reservoir by a supply passage to supply fluid to the reservoir, a supply access valve connected with the supply passage and operable to block flow from the external supply port to the reservoir in a closed position and to permit flow from the external supply port to the reservoir in the open position, and a controller in communication with the supply access valve for controller operation of the supply access valve from a closed position to an open position in response to receipt of an authorized supply signal at the controller.
US11845644B2 Flavor infusion dispenser
A flavor infusion dispenser is provided. The flavor infusion dispenser may include a refrigeration unit configured to store a beverage container, a beverage tower coupled to the refrigeration unit and configured to transport a beverage from the beverage container, a faucet coupled to the beverage tower and having a handle configured to activate flow of the beverage from the beverage container through the beverage tower, a nozzle coupled to the faucet, at least one flavor container for storing flavoring for the beverage, at least one flavor line coupled to the nozzle and configured to transport flavoring from the at least one flavor container, and a pump configured to pump flavoring from the at least one flavor container to the nozzle via the at least one flavor line. The nozzle may be configured to mix the beverage and the flavoring, and dispense a flavored beverage.
US11845643B2 Beverage dispensing
Among other things, beverages are dispensed from one or more beverage dispensers based on selections made by users. Information about the dispensing of the beverages is sent to a central server where it is used to manage a variety of functions including replacement of depleted supplies of components. Various features of the beverage dispensers enable the beverages that are dispensed to be uniform and appealing to users.
US11845641B1 Flat floor jack
A flat floor jack is configured to be maneuverable and manage a heavy load. The flat floor jack has a handle attached to a first side wall and a second side wall. A lifting arm is rotatably coupled to the first side wall and the second side wall. A hydraulic cylinder is joined to the first side panel and the second side panel. A first axel is arranged through the first side wall and the second side wall and attached to a first roller and a second roller. A second axel is arranged through the first side wall and the second side wall and attached to a third roller and a fourth roller. Each roller has a roller bearing assembly that has hundreds of small spheres arranged adjacent to one another such that weight from the roller is distributed among the hundreds of small spheres.
US11845640B1 Crane assembly
A crane assembly is configured to move a camera. The crane assembly has a base support assembly which includes a box support, joined to at least three box leg sleeves extending outward and downward from the box support. A plurality of legs where each leg is joined to one of the box leg sleeves. A plurality of drop in leg forks where each drop in leg fork joined is to at least one of the legs. A plurality of spreader bars where each spreader bar is joined to two of the drop in leg forks.
US11845637B2 Stairlift for a right hand user and a left hand user
The present invention refers to a stairlift (1) comprising a first armrest (10) and a second armrest (10), wherein each armrest (10) is adapted to comprise at least one module (11, 12), and wherein said at least one module (11, 12) is adapted to provide at least one user control function; characterized in that the at least one module (11, 12) is adapted to be interchangeable between the first and second armrests (10).
US11845635B2 Elevator systems, guide rail assemblies and methods of installing elevator systems
An elevator system (2) comprising a hoistway (4), an elevator car (6) and a counterweight (8) arranged to move within the hoistway (4). The system (2) further includes a first counterweight guide rail and a second counterweight guide rail arranged to guide the counterweight within the hoistway (4) and a guide rail bracket (32) which connects the first and second counterweight guide rails together. An elevator machine (10) is arranged to drive a tension member (14), which couples the elevator car (6) and counterweight together (8), to move the elevator car (6) within the hoistway (4). The system (2) further includes a friction reducing element (36) arranged on the guide rail bracket (32) such that if the tension member (14) moves towards the guide rail bracket (32) during operation of the elevator system (2), the tension member (14) contacts the friction reducing element (36).
US11845633B2 Overload valve assembly for a pneumatic vacuum elevator
An overload valve assembly for a pneumatic vacuum elevator is disclosed. The overload valve assembly for a pneumatic vacuum elevator is characterised by a fastening means, a pad with a centre hole, an arresting plate with a centre hole, a disc plate with a centre hole, a bottom bush, a spring and a top bush bounded with a nut. Here, the pad, the arresting plate, the disc plate, the bottom bush, the spring and the top bush bounded with the nut is fitted over the fastening means. The overload valve unit is configured to function based on spring actuation mechanism and ensure the maximum permissible limit of pay load in the elevator cabin assembly.
US11845632B2 Method of predictively maintaining elevator driving unit
The present invention provides a method of predictively maintaining an elevator driving unit which distinguishes between a condition when moving an elevator upward and a condition when moving the elevator downward, collects driving information of the driving unit (information on a change over time in current values) in a normal state, collects driving information of the driving unit before the occurrence of breakdown, sets critical levels based on the collected information, detects in real time an abnormal symptom of the driving unit by comparing the driving information of the driving unit, which is collected in real time, with the set critical level, and then performs stable predictive maintenance of the elevator driving unit, thereby efficiently preventing a safety accident of the elevator caused by a breakdown of the elevator driving unit.
US11845630B2 Image forming apparatus
An image forming apparatus includes a first feeding portion including a first cassette and a first feed roller; and a second feeding portion including a second cassette and a second feed roller and disposed below the first feeding portion. The sheet fed by the second feed roller is conveyed toward an image forming portion through an intermediate path provided in the first cassette. The image forming apparatus further includes a controller to operate a display unit to display information that inhibits drawing of the first cassette, in a case where a first detection portion detects that the first cassette is empty and where the second feeding portion is performing a sheet feeding operation, with the first cassette being drawable from the apparatus body whether the second feeding portion is performing a sheet operation or not.
US11845624B2 Conveying device and liquid discharge apparatus
A conveying device includes a rotating carrier, an inlet rotary body, an outlet rotary body, a downstream conveyor, and an inching controller. The rotating carrier carries a sheet. The inlet rotary body transfers the sheet to the rotary carrier from upstream of the rotary carrier in a conveyance direction of the sheet. The outlet rotary body transfers the sheet to a downstream area from the rotary carrier in the conveyance direction. The downstream conveyor conveys the sheet downstream from the outlet rotary body in the conveyance direction. The inching controller performs an inching operation to convey the sheet on a conveyance path including at least the downstream conveyor. The inching controller causes at least the outlet rotary body and the downstream conveyor to perform a conveying operation in conjunction with each other in the inching operation.
US11845623B2 Winding apparatuses, systems, and related methods
Winding apparatuses for winding sheet material and related methods are disclosed herein. The winding apparatuses can include a set of winding drive rollers. Each drive roller of the winding drive rollers can have drive wheels spaced apart along the respective drive roller with a winding zone between the winding drive rollers. The winding apparatus can also include a feed system positioned before the set of the winding drive rollers for moving sheet material along a travel path in a machine direction into the winding zone.
US11845616B1 Flattening and item orientation correction device
A device for manipulating items for facility operations is described. The device includes a first arm assembly that includes a first arm, a second arm parallel to the first arm, a first shaft disposed between the first arm and the second arm at a first location along the first arm and the second arm, and a first head attachment disposed between the first arm and the second arm at a second location along the first arm and the second arm. The device also includes a first driver coupled to the first shaft and configured to control movement of the first arm assembly about a first axis extending along a length of the first shaft. The device further includes a second driver coupled to first head attachment and configured to control movement of the first head attachment about a second axis extending along a length of the first head attachment.
US11845614B2 Systems and methods for processing objects including semi-autonomous stations and automated output processing
A semi-autonomous processing system for processing objects is disclosed. The semi-autonomous processing system includes an input conveyance system for moving objects to a presentation area, a perception system including perception units that are directed toward a detection area for providing perception data regarding an object in the presentation area, at least two transport systems, each of which is adapted to receive the object and move the object in either of reciprocal directions, and a manual workstation area between the perception area the at least two transport systems.
US11845613B1 In-built divert elements for motorized conveyor rollers
Apparatuses, methods and systems comprising element in-built diverts for motorized conveyor rollers are provided. An example conveyor roller can include a housing that forms a cylindrical tube. The conveyor roller includes a plurality of element in-built diverts disposed on an exterior surface of the housing. The plurality of element in-built diverts are reconfigurable between one or more orientations with respect to the housing to divert an item an angle with respect to the housing.
US11845612B2 Friction drive wheel construction
A friction drive wheel for conveyor systems includes a cylindrical central disk formed of aluminum. Joined to the curved outer surface of the aluminum disk is a base layer that is cylindrical and sleeve-like and coaxial with the disk. The base layer is formed of a hard polymer (like polyurethane) material, with a hardness in the range of 75 Shore D, to eliminate torsional stress and flexure at the mechanical interface between the base layer and the central disk. A tread layer is secured about the base layer, formed of a softer polymer (like polyurethane) that is more yielding and compliant in contact with the trolley to maximize the frictional engagement. The base layer serves as a thermal insulator between the outer tread layer and the central disk, protecting the bond at the base/central disk interface.
US11845611B2 Bristle brush and conveyor belt formed by a plurality of said bristle brushes
The bristle brush comprises a support plate (1), a plurality of flexible bristles (2) emerging from one of the surfaces thereof, the ends of the bristles (2) furthest from the support plate (1) defining a support surface intended to receive a part to be transported and/or cut, wherein said support plate (1) comprises a leading edge (11) and a trailing edge (12), said leading (11) and trailing (12) edges comprising complementary shapes. It enables a conveyor belt formed by said brushes to achieve very small turning radii.
US11845609B2 Pallet spacing system and method
A system and method for operating robotic pallet transportation carts and providing uniform spacing between pallets of goods, to improve the vertical alignment of the gaps between the pallets of a multilevel commercial warehouse rack. Indicators are positioned along a storage lane, such as on side walls of cart support rail structures, on the left and/or right sides with respect to the pallet transportation cart. The cart has one or more sensors (optical, magnetic and otherwise), such as on a side of the cart to detect the indicators on the side of the lane. The cart is programmed to count the indicators and lower the pallet of goods after sensing a selected indicator number. By spacing the indicators an appropriate distance apart, the pallets can be arranged to have vertically aligned gaps, even if there are minor variations in the length of pallets of goods.
US11845608B2 Suspension type transport vehicle and storage system
A suspended transport vehicle travels along a track supported by a ceiling and transfers an article to a shelf of a rack installed on a floor, the suspended transport vehicle has a driving part, a first traveling part and a second traveling part, a ceiling-side member that is suspended downwards from the first traveling part and the second traveling part and has a transferring part that transfers the article to the shelf of the rack, a floor-side member that is provided so as to be capable of relative movement with respect to the ceiling-side member and has travel rollers being contacting parts in contact with a first guide part installed on the floor, and a distance sensor that detects a relative distance between the ceiling-side member and the floor-side member.
US11845607B1 Two-part garbage can
A trash can with a separable base and sidewall. The base and the sidewall have cooperating engaging structures, such as slots in the sidewall and tabs on an inner face of a perimeter wall of the base. The base has a projecting ledge on an outer face of the perimeter wall. The sidewall and base are separated from one another by depressing the projecting ledge, thereby causing the base to resiliently deform and move at least one of the cooperating engaging structures of the base out of engagement with its counterpart on or in the sidewall.
US11845606B2 Container for aerosol system
A cylindrical shaped container for aerosol system, having a body for housing a first component substances, a dome-shaped disk arranged at one end of the body; a mounting cup arranged at other end of the body to accommodate a first valve assembly, and an inner compartment joined hermetically to the first valve assembly. The inner compartment is positioned within the body for housing a second component substances. The second component substances are injected via the first valve assembly having a valve housing. The valve housing houses a bottom inner sleeve on one end of the valve housing, and a protrusion lever on the other end.
US11845605B2 Valve arrangement and dispensing apparatus
A valve arrangement for dispensing a fluid is proposed. The valve arrangement comprises a valve plate for fixing the valve arrangement to a container, a valve housing and a fixing part for fixing the valve housing to the valve plate. The fixing part is welded with the valve plate. Furthermore, a dispensing apparatus with a container and a valve arrangement as well as a production method are proposed.
US11845604B2 Texture material dispensing system including a foldable handle and trigger
Described herein is a texture material dispensing system that includes a foldable handle and trigger. The texture material dispensing system may be used for dispensing a texture material onto a target surface, such as a ceiling.
US11845602B2 Tank and method
A tank for the storage of liquid or gaseous substances with a fiber-reinforced plastic sheathing, which limits at least one interior space for holding the materials to be stored. At least one circumferential section of the fiber-reinforced plastic sheathing comprises an evacuable sandwich structure, which completely encloses the circumferential section. As a result, the tank has a low weight with a high thermal insulation capacity. Furthermore, a reliable explosion protection of the tank is provided. Furthermore, a method for manufacturing a tank for the storage of liquid or gaseous substances is provided.
US11845601B2 Method and apparatus for storing food
A system, apparatus, and method of storing food including a storage container having a base; a resilient liner nesting in the base, and a lid that interlockingly engages with the liner and/or base to close off access to foodstuffs retained in a compartment defined by the liner. A valve assembly in the lid is actuated by a pump to evacuate air from the liner's compartment and create a vacuum or near-vacuum condition therein. Apertures defined in the wall of the base allow air to flow into a compartment of the base as the resilient liner shrinks around the food. The closed storage container may be placed in a freezer to freeze the food therein. For defrosting, the base of the closed storage container is placed in a volume of water, some of which flows through the apertures in the base's wall and comes into direct contact with the liner.
US11845595B2 Container management system
A container management system including a lid assembly configured to engage/disengage a collar of a container to close and open an aperture thereof, wherein the lid assembly includes an interior lid compartment in communication with an interior portion of the container when the lid assembly engages the collar, a reactive substance configured to undergo a physical change in response to a change of an environment condition at the aperture when the lid assembly engages the collar. The physical change of the reactive substance turns the lid assembly from a first operative condition wherein the lid assembly can be disengaged from the collar to open the aperture to a second operative condition wherein a portion of the lid assembly cannot be disengaged from the collar and closes the aperture.
US11845594B1 Re-wrap packaging
The invention relates to a packaging system including box and wrapping papers of conventional type having a square folded bottom and side folds providing a box shaped assembly where the proposed assembly can be used for packaging of various types of items. The assembly is easy to use and can be used for packaging of consumer goods, gifts, surprise or mystery items, in promotional schemes or brand activation and marketing activities.
US11845592B2 Method of making blank
The method includes making a blank from a single web of material, the making including first configuring a first side panel and a second side panel to extend from first opposing ends of a bottom panel, second configuring a ramp panel to extend from a first edge of the first side panel, and third configuring a top panel and a lid panel to extend from second opposing ends of the bottom panel.
US11845590B2 Self-adjusting preload for memory alloy wire
A preload mechanism for an actuator is disclosed that includes a rotating element configured to rotate about a pivot. The rotating element has a first contact point that is configured to couple to the actuator such that contraction of the actuator displaces the first contact point such that the rotating element rotates from a first position to a second position. The preload mechanism also includes a bias element with a first end that is coupled to a second contact point of the rotating element and a second end configured to be pinned relative to the pivot. The bias element has a line of action extending from the second end through the first end. The line of action has an offset distance that is the minimum distance between the line of action and the pivot. The offset distance has a first value when the rotating element is in the first position and a second value when the rotating element is the second position, the second value being smaller than the first value.
US11845589B2 Bag body, film body, and method for manufacturing bag body
A bag includes a bag body defining a housing space, an elongated member provided on a first face portion of two face portions forming the bag body, and a tab. The elongated member includes an elongated tearing guide piece, a belt-shaped base provided between a second face portion and the tearing guide piece along a longitudinal direction of the tearing guide piece. The tab has an outer edge defined in the first face portion by a cutting line penetrating through the belt-shaped base and the first face portion. A protector covering the tab is provided on a side of the first face portion provided with the belt-shaped base.
US11845588B2 Pouch enclosure with filling slit
A filling slit is formed in a first panel of web material of a flexible pouch enclosure formed from the first panel and an opposing second panel of the web material and having a resealable closing assembly having interlocking male and female members joined to a flange. After the flexible pouch enclosure is at least partially filled with a product through an opening in the first panel of the web material that is created by the filling slit, the filling slit is closed by sealing the first panel to the flange of the resealable closing assembly.
US11845581B2 Swirl bell bottle with wavy ribs
An apparatus is provided for a container comprising a base, a bell, a sidewall between the base and the bell, a neck and a finish which define an opening to an interior of the container, and a shoulder between the sidewall and the bell. Strap ribs extend from a central portion of the base and terminate at the sidewall. The strap ribs cooperate with vertically aligned recessed columns of the sidewall to resist bending, leaning, crumbling, or stretching along the sidewall and the base. An inwardly offset portion of the sidewall is disposed between each pair of adjacent recessed columns. The inwardly offset portions of the sidewall are configured to resist outward bowing of the sidewall due to internal pressure of contents within the container.
US11845580B2 Method and device for producing and inspecting a package
A method for producing and inspecting a package comprising at least one product cavity of a formed part sealed by a lidding film comprises the steps of: (a) sealing the lidding film to the formed part along a seam by means of a sealing device, which comprises a sealing contour with a plurality of segments; (b) detecting, by means of the sealing device, a parameter characteristic of the sealing quality of the seam in each segment; and (c) detecting a problem with the sealing according to step (a) based on the parameter detected according to step (b) in each segment.
US11845577B2 Conveyor device for conveying food products
A method of using a conveyor device is provided for conveying food products in stacks or interleaved units made of a plurality of slices of cheese or meat products. The method formats the food products in a specific product format on a plurality of parallel conveyor tracks, and fills a product gap on one of the plurality of parallel conveyor tracks incoming on the input side with a food product so that on the output side all parallel conveyor tracks are supplied with the food products.
US11845573B2 Configuration construction and attitude control method for pyramid deorbit sail
Provided is a configuration construction and attitude control method for a pyramid deorbit sail. By taking into consideration environmental perturbation like atmospheric resistance perturbation and non-spherical earth perturbation, a dynamics model featuring three-dimensional orbit-and-attitude coupling based on position vectors and quaternion descriptions, the deorbit sail is taken as a rigid body, a spacecraft body is taken as a mass point, airflow obstruction is considered in the windward area, thereby improving the precision of the dynamics model; based on this model, the law of influence of the configuration parameters in the deorbit sail, such as a cone angle and a strut length, on the attitude stability and deorbiting efficiency of the spacecraft in different cases is analyzed, the configuration parameters of the pyramid deorbit sail system are analyzed and optimized according to the derived law, so as to obtain a pyramid deorbit sail achieving high attitude stability and high deorbiting efficiency.
US11845572B2 System and method for providing spacecraft-based services
A system for providing spacecraft-based services, preferably including one or more spacecraft and one or more ground control elements, wherein the spacecraft can include one or more payloads associated with one or more organizations. A method for providing spacecraft-based services, preferably including receiving service requests, determining request assignments, and/or controlling spacecraft.
US11845570B2 Aircraft system operational testing
A method includes obtaining a first test matrix for a first aircraft system and a second test matrix for a second aircraft system. The method also includes, during a first operational test of the first test matrix, obtaining sensor data that includes second sensor data that is not specified by the first test matrix. The method includes evaluating a second operational test of the second test matrix by processing the second sensor data using a second analytic model of the second aircraft system. The method also includes generating second predicted sensor data based on the evaluation of the second operational test. The method includes generating a second error measure by comparing a second subset of the sensor data to the second predicted sensor data. The method includes determining, based at least in part on a range of the second sensor data, a test coverage metric of the second test matrix.
US11845564B1 Aircraft seatbelt buckle fasten indication system
The aircraft seatbelt buckle fasten indication system comprises a monitoring circuit, a plurality of tracking structures, a plurality of lap belts, and a plurality of vehicle seats. Each of the plurality of tracking structures attaches to a lap belt selected from the plurality of lap belts. Each individual tracking structure selected from the plurality of tracking structures attaches to a lap belt selected from the plurality of lap belts such that the selected individual tracking structure monitors the status of the lap belt. The status of the lap belt is selected from the group consisting of: a) the lap belt is properly fastened; and, b) the lap belt is not properly fastened. The monitoring circuit monitors each of the plurality of tracking structures to individually determine the status of each individual lap belt. The monitoring circuit provides a visual display of the status of each individual lap belt.
US11845563B2 Information display device
An information display device is attachable to a structure, and includes a display panel and a surface member. The display panel has a display surface and is configured to display information on the display surface. The surface member is disposed on a display surface side of the display panel and is configured such that only the information displayed on the display surface of the display panel is visible through the surface member when the display panel is turned on. The surface member includes a first layer disposed on a front side, and a second layer disposed on the display panel side with respect to the first layer. The second layer is configured to compensate for a difference of transmittance depending on a position on the first layer.
US11845560B2 Electrothermal heater mat
In manufacturing an electrothermal heater mat, there is provided a preform which comprises a laminated stack of dielectric layers which are made of thermoplastic material and include a central layer or group of layers which include(s) reinforcement and first and second outer groups of layers which do not include reinforcement. The preform includes a heater element and the preform has a first configuration. The preform is then heated to a temperature (e.g. 180° C.) between the glass-transition temperature of the thermoplastic material and the melting point of the thermoplastic material, and the heated preform is formed into a second configuration which is different to the first configuration so as to produce the heater mat.
US11845557B2 Springless dress cover and lower closeout system for passenger seat
A springless lower closeout system for a passenger seat includes left-side and right-side seat spreaders defining a lower aft portion of the passenger seat between them. Each seat spreader includes a restrictive channel extending along the left and right sides of the seat spreader, oriented toward the lower aft portion of the passenger seat. A dress cover extends in a taut state between the left-side and right-side seat spreaders. The dress cover includes cord elements on its left and right edges, the cord elements insertable into the left-side restrictive channels to directly connect the dress cover to the seat spreaders, closing out the lower aft portion of the passenger seat. A zipper or fastener connecting the dress cover and either edge may be partially unfastened to adjust the tension of the dress cover and facilitate attachment or removal of the cord elements to or from the restrictive channels.
US11845556B2 Energy absorption device for a seat of a vehicle and seating system with such an energy absorption device
The present invention relates to an energy absorption device for a seat of an aircraft, in particular of a helicopter, with at least one impact mechanism (2, 4) and at least one energy absorber (1) coupled with the impact mechanism (2, 4), wherein the impact mechanism (2, 4) acts on the energy absorber (1) for the energy absorption at least in the case of a crash.
US11845554B2 Drone payload release assembly
A payload release assembly is disclosed. The payload release assembly includes a body defining a plurality of fingers each defining an opening. A plurality of payload retention pockets are defined between adjacent fingers of the plurality of fingers. A release pin is dimensioned to be received within the openings defined by the plurality of fingers. A motor is adapted to drive the release pin into engagement and out of engagement with the openings defined by the plurality of fingers, such that payloads secured within the payload retention pockets are released from the payload release assembly when the motor drives the release pin out of engagement with a respective opening defined by the plurality of fingers.
US11845553B1 Apparatus and method for ordinance mounting system
Embodiments of a payload attachment system secure a payload to a wing or fuselage of the drone 102 (or another type of aircraft) using one or more vacuum mounting modules, wherein each vacuum mounting module comprises at least one vacuum pump controllably coupled to a microcontroller, a vacuum cup fluidly coupled to the at least one vacuum pump, and a transceiver that receives an instruction corresponding to one of a vacuum cup actuation signal or a vacuum cup release signal.
US11845548B2 Jet powered personal flying machine with customizable framework and a single control stick, attached at the front and center of the base frame
A jet powered personal flying machine composed of a customizable framework consisting of separate bolt-on parts or sections that can be swapped out or switched, including a base frame containing a plurality of mini jet engines, a shell or fuselage, a fuel tank, a flight computer, a plurality of electronic buttons and controls, a parachute, footstands on both sides for the user to place their feet and a single control stick consisting of a metal or carbon fiber tube attached at the front and center of the base, and protruding upwards and slightly forward from the base frame, of which contains electronic buttons and controls for the user to use in flying the machine.
US11845540B2 Apparatus and method for determining aircraft tire pressure
An apparatus for determining tire pressure of an aircraft tire. The apparatus includes a processing system configured to: obtain a first set and a second set of tire measurement data for an aircraft, wherein the first set is from a start of a flight cycle and the second set is from a time before the first set; and determine a steady state tire pressure based on the first and second sets of measurement data.
US11845539B2 Stall trigger system
A stall trigger system is disclosed having an aircraft wing tip or aircraft wing tip device, a plurality of sets of stall triggers distributed along a span of the aircraft wing tip or aircraft wing tip device. Each set of stall triggers comprises one or more stall triggers which can be activated to trigger local separation of air flow over the aircraft wing tip or aircraft wing tip device, and each set of stall triggers has a different activation threshold. A control system configured to monitor a parameter, and activate each set of stall triggers in response to the parameter reaching its respective activation threshold.
US11845534B2 Slanted duct stators
A ducted-rotor aircraft includes a fuselage and first and second ducts that are coupled to the fuselage. Each duct includes a duct ring, a rotor having a plurality of blades, a hub that positions the rotor such that the blades define a blade plane of rotation within the duct ring, and a plurality of stators that are coupled to the hub at respective locations aft of the blade plane of rotation. Each of the plurality of stators defines a leading edge that is slanted toward the blade plane of rotation. The leading edges of the stators are slanted to follow a contour defined by the blades. The leading edges may also be slanted to maintain a distance of at least one blade inboard chord length between the leading edges of the stators and respective trailing edges of the blades.
US11845531B2 Fireproof and thermal insulator product
A fireproof and thermal insulator product (1) including an Alkaline Earth Silicate (AES) material (2), and at least one of the following: a liquid barrier film (5), an FRP (Fiber Reinforcement Plastic) layer (4), cork (3), wherein the liquid barrier film (5) and the FRP layer (4) are staked onto the AES material (2), and wherein the cork (3) material is also staked onto the AES material (2) or embedded into said AES material (2) in where said cork (3) is configured as a plurality of strips performing a grid structure infilled with the AES material (2).
US11845529B2 Light for a window of an aircraft
A pane assembly (2) for a window (8) arranged in the outer wall (4) of an aircraft (6) in a window plane (10) contains a transparent cover pane (12) in a cover plane (14), a switching film (16) in a scattering plane (18), which is switchable between a transparent state (ZT) and a diffuse state (ZD), a luminous film (20) in a light plane (22) having LEDs (24), wherein a spacing (A) between each two LEDs (24) in relation to one another is at least five times their transverse extension (Q), wherein the pane assembly (2) is arranged in front of the window (8) in an installed state (M), so that scattering plane (18), light plane (22), and window plane (10) extend in parallel to one another and the luminous film (20) is arranged between the window (8) and the switching film (16), and window (8), switching film (16), and luminous film (20) are located aligned one behind another on the line of sight (26).A window assembly (40) contains the window (8) and the pane assembly (2) arranged in front of it in the installed state (M).
US11845526B2 Raw water isolator for watercraft
A raw water isolator for watercraft for providing treated fluid to loop of air conditioning units, freezers, ice makers, gyro stabilizers and the like systems. The raw water isolator provides a closed loop of treated fluid to prevent such systems from exposure to raw water known to contain biological material capable of fouling the units, and associated corrosion when salt water is used for the cooling mechanism. The apparatus employs a storage and expansion tank for holding a volume of fluid that is circulated through the marine units. A heat exchanger selected for ease of cleaning provides heat transfer between the cooling fluid and raw water.
US11845525B2 Marine power plant assembly
A marine plant assembly comprising a floating vessel and a plant operating unit attached to a buoyancy vessel in such a way that the operating unit is at least partially submerged during operation. At least one link element provides a hinged connection between the operating unit and the buoyancy vessel, thereby to allow movement of the operating unit from its submerged operating position to above the water level and adjacent the buoyancy vessel by said link element rotating into a position substantially parallel to the buoyancy vessel.
US11845523B2 Engine control
A method for controlling a propulsion operation of a propulsion unit to reach a desired speed of a marine vessel. The method comprises obtaining a target speed configuration indicating the desired speed of the marine vessel, obtaining a current speed value associated with a current speed of the marine vessel, obtaining a fill level value associated with a fill level of one or more ballast tanks of the marine vessel, and controlling the propulsion operation of the propulsion unit to reach the desired speed based on the target speed configuration, the current speed value, and on the fill level value.
US11845518B2 Small planing watercraft and processing method for small planing watercraft
A small planing watercraft includes: a body including a storage box and a lid, the storage box including an opening, the lid releasably closing the opening; an opening and closing sensor detecting opening and closing of the lid; and processing circuitry determining whether the lid is open based on a result of detection of the opening and closing sensor, and, when determining that the lid is open, outputting a signal indicating that the lid is open.
US11845516B2 Pontoon boat
A pontoon boat includes port and starboard pontoons and cross members connecting the pontoons. A shock absorber may be installed at each point of connection of the pontoons to the cross members. A cross member may be embodied as a double-webbed beam having first and second parallel flanges and first and second webs disposed between and connected to the flanges. Each pontoon may include a two-stage lifting strake having a first surface and a second surface inclined from the first surface.
US11845514B2 Bicycle sprocket
A bicycle sprocket for a sprocket cassette comprises a sprocket main body which extends about a virtual sprocket axis about which the sprocket is rotatable during intended operation on a bicycle. In the case of a single release tooth being formed, a release-side stabilizing tooth is arranged in the circumferential region of extent of an upshift recess formation. The release-side stabilizing tooth has an inner tooth contact surface which has a greater axial spacing to an axial reference position than an inner tooth contact surface of the reference tooth. Additionally, or alternatively, in the case of a single catch tooth being formed, a receiving-side stabilizing tooth is arranged in the circumferential region of extent of a downshift recess formation. The receiving-side stabilizing tooth has an inner tooth contact surface which has a greater axial spacing to the axial reference position than the inner tooth contact surface of the reference tooth.
US11845509B2 Bicycle suspension
A bicycle has a frame with a rear suspension defining a suspension travel. The rear suspension includes a wheel link, a separate brake link, and a shock linkage. The wheel link is connected to the frame. The wheel link and the brake link are connected to each other via a floating pivot concentric with the rear wheel axis. The wheel link having an idler with a pivot axis below a projection line extending from the floating pivot to the main fixed pivot axis. The main fixed pivot axis is higher than the floating pivot when the rear suspension is at rest. The shock linkage is mounted to the frame via a fixed shock linkage pivot and interconnects the brake link and a shock absorber fixed on the frame.
US11845507B2 Motorcycle foot peg assembly with angled teeth
A motorcycle foot peg having forwardly and rearwardly leaning teeth is provided, the teeth for engaging more optimally the soles of footwear worn by a rider when the rider is angling his feet on the leading or trailing edge of the foot peg.
US11845506B2 Bottle cage
A bottle cage includes a storage space. The storage space has a wide section and a narrow section arranged axially along a reference line. The wide and the narrow sections include widths thereof extending transversely to the reference line. The wide section has a first width and the narrow section has a second width respectively. The second width is smaller than the first width. The storage space includes an electronic device with satellite positioning function installed therein in a separable installation manner.
US11845505B2 Seat post assembly
A bypass device for a seating component such as an adjustable seating assembly for a bicycle may be provided to redistribute fluid preferentially by density. The bypass device may be operable to redistribute a low density compressible fluid or a mixed phase of low density compressible and high density non-compressible fluids within the seating component.
US11845502B2 Removable universal lateral track extension system
A universal removable lateral track extension system includes an extension track assembly removably couplable outboard of an original lateral track at a selected displacement width, the assembly further including a track frame plate, first and second receiver hitches, a drive coupler removably couplable to the corresponding drive sprocket of the tracked equipment, the drive coupler including a drive bearing assembly and connected drive sprocket in line with the extension track track rollers, a drive sprocket coupler and extension axle removably couplable from the drive sprocket connector to the drive bearing assembly, and a continuous track extending around the extension track track rollers and drive coupler.
US11845499B2 Control device for power steering device
A control device for a power steering device includes a low-pass filter unit including a cutoff frequency adjustment unit configured to adjust a cutoff frequency for partially attenuating a component of an input signal, set the cutoff frequency to a first cutoff frequency when a steering torque signal is lower than a first predetermined torque value, and to set the cutoff frequency to a second cutoff frequency lower than the first cutoff frequency when the steering torque signal is equal to or higher than the first predetermined torque value.
US11845496B2 Vibration damping structure
A vibration damping structure includes a panel which is a structure and a damping member joined to the panel. The damping member has a plurality of joined portions joined to a mating surface of the panel through respective joined surfaces in the X direction, and a plurality of spacing portions recessed toward the side opposite to the panel in the Z direction between adjacent joined portions. The damping member is formed such that the damping member is higher in damping than the panel and a resonance frequency of the damping member is formed such that it is substantially the same as a primary resonance frequency of the panel.
US11845495B2 Hood mounting structure
A hood mounting structure includes: a fender apron upper member provided along a length direction of a vehicle body; a hood disposed on a front portion of the vehicle body; and a hood hinge including a hinge upper arm connected to a lower part of the hood and a hinge lower arm mounted on a side of the fender apron upper member.
US11845494B2 Vehicle body structure
A vehicle body structure includes: a roof panel, a rail disposed below the roof panel and extending in a left-right direction, a brace disposed below the roof panel and coupled to an end of the rail and extending from the rail toward in a front-rear direction, a reinforcing member reinforcing a connection portion where the rail is coupled to the brace. A first end of a main wall of the reinforcing member is welded to a first-end-side flange of the rail. A second end of the main wall is welded to a second-end-side flange of the rail and to an end of the brace on the first side in the front-rear direction. The reinforcing member includes flanges welded to the bottom wall of the rail.
US11845490B1 Vehicle alignment assembly
An alignment assembly that includes a body that defines a bolt aperture and at least one pin aperture. A control arm is proximate the body and includes a bushing with a bushing aperture. A bolt extends through the bushing aperture and the bolt aperture. The bolt has a front portion and an end portion opposing the front portion. A flag nut is coupled to the end portion and includes a plate with at least one aperture. At least one pin extends through the at least one pin aperture and the at least one aperture. A position of the pin at least partially determines a position of the control arm.
US11845487B2 Steering column breakaway and energy absorption apparatus
An article for a steering column assembly (10) including a connection member (60) having a base portion (62) adapted to be attached to a column tube (30) of the steering column assembly (10) and opposing side walls (64) extending from the base portion (62). The article further includes an energy absorption member (80) having a first generally flat segment (82), a second generally flat segment (84) generally parallel to the first generally flat segment (82), and a curved portion (86) therebetween. The energy absorption member (80) extends from the base of the connection member (60). The present teachings also envision a telescoping adjustment subassembly and a steering column assembly (10) employing the article.
US11845484B2 Motorized beach cart
The present disclosure provides a motorized beach cart for transporting beach necessities. The motorized beach cart includes a collapsible frame and a handle is hingedly connected to the collapsible frame. The motorized beach cart includes a battery electrically wired to an electric motor disposed within a protective casing, and at least a first USB port is provided within an exterior wall of the protective casing. A drive assembly is disclosed which is adapted to removably connect to a back end of a beach cart.
US11845481B2 Rail and train system
A rail and train system has at least a rail pair on which a rail vehicle that is provided with at least one wagon is movable. In the wagon, at least one lifting device is accommodated with which containers can be transported through an opening in the floor of the wagon and which is movable transverse to the length direction of the wagon. The rail vehicle can be provided with a chassis that is formed by two chassis parts that are positioned at a distance behind each other in the travel direction.
US11845475B1 Tri-mode locomotive
A locomotive consist including a pair of fuel-electric locomotives, each having a prime mover engine and a power transmission system including a main generator and traction motors coupled to driving wheels, a high voltage electrical connection operable in an on state or an off state, and a computer controller. The pair of fuel-electric locomotives is configured to selectively cooperate to operate in three different operating modes as controlled by the computer controller: (1) a prime mover mode, (2) a mother/slug mode, and a mother/inoperative mode.
US11845471B2 Travel assistance method and travel assistance device
A travel support method for a vehicle comprises estimating a position of a subject vehicle, generating a subject vehicle traveling route, based on the estimated position of the subject vehicle and map information, calculating a degree of first reliability indicating reliability of the subject vehicle traveling route, detecting a preceding vehicle traveling ahead of the subject vehicle, generating a preceding vehicle traveling route, calculating a degree of second reliability indicating reliability of the preceding vehicle traveling route, based on the preceding vehicle traveling route, calculating, based on the degrees of the first reliability and second reliability, an integration ratio for integrating the subject vehicle traveling route and the preceding vehicle traveling route, calculating a target traveling route of the subject vehicle by integrating the subject vehicle traveling route and the preceding vehicle traveling route at the integration ratio, and controlling the subject vehicle based on the target traveling route.
US11845468B2 Method and system for operating an autonomous agent with incomplete environmental information
A system for operating an autonomous agent with incomplete environmental information can include and/or interface an autonomous operating system and an autonomous agent. A method for operating an autonomous agent with incomplete environmental information includes any or all of: receiving a set of inputs; determining a set of known objects in the ego vehicle's environment; determining a set of blind regions in the ego vehicle's environment; and inserting a set of virtual objects into the set of blind regions; selecting a set of virtual objects based on the set of blind regions; operating the autonomous agent based on the set of virtual objects; and/or any other suitable processes.
US11845467B2 Systems and methods for directing a parked vehicle to travel from a first parking spot to a second parking spot
The disclosure generally pertains to systems and methods for directing a parked autonomous vehicle to travel autonomously from a parking spot to a pickup spot. In one example scenario, a user of a user device such as a smartphone, may launch a software application in the smartphone for summoning the autonomous vehicle that is parked in a parking lot or a road, for example. The software application displays a graphical rendering of the parking area together with an icon that can be dragged and dropped by the user at any convenient pickup spot in a valid drivable area shown on the graphical rendering. The user places the icon upon a desired pickup spot and the smartphone transmits a command to the autonomous vehicle to travel to the pickup spot. A real-time representation of a progress of the autonomous vehicle towards the pickup spot may be displayed on the user device.
US11845465B2 Autonomous lateral control of vehicle using direct yaw moment control
A method includes identifying a path to be followed by an ego vehicle. The method also includes determining a desired yaw rate and a desired yaw acceleration for the ego vehicle based on the identified path. The method further includes determining a desired yaw moment for the ego vehicle based on the desired yaw rate and the desired yaw acceleration. In addition, the method includes distributing the desired yaw moment to multiple wheels of the ego vehicle such that the distributed desired yaw moment creates lateral movement of the ego vehicle during travel along the identified path. In some cases, the desired yaw rate and the desired yaw acceleration for the ego vehicle may be determined based on nonlinear kinematics of the ego vehicle, and the desired yaw moment for the ego vehicle may be determined based on a single-track dynamic model of the ego vehicle.
US11845463B2 Dynamic AR notice
The disclosure relates to a device for the improved visualization of a notice in a motor vehicle. A contact-analog head-up display places information in direct contact with the environment. In contrast to conventional head-up displays, the information appears as part of the environment. Some embodiments provide an information container that is placed at a distance x from the vehicle which grows corresponding to the reduction of the distance x, and is placed fixed relative to the environment to produce the effect of a container located in reality. The necessity of an interaction may be communicated by the element remaining stationary. That is, shortly before the position of the information container is reached, it remains immobile in the field of vision and is “pushed” in front of the ego vehicle. This makes it immediately apparent that an operation is needed to acknowledge the pop-up respectively to thereby trigger an action.
US11845461B2 Thermal monitoring system for trailer wheel area
Monitoring critical areas of a trailer for thermal events, including: a plurality of sensors placed at or near the critical areas of the trailer, the plurality of sensors to sense the thermal events at the critical areas as sensor data, wherein the critical areas include at least tire, brake, and wheel end; a main controller to receive and monitor the sensor data measured by the plurality of sensors, the main controller to trigger at least one of alerts and warnings; an indicator light to activate the alerts; and an alarm to sound the warnings.
US11845458B2 Vehicle drive force control method and vehicle drive force control device
A vehicle drive force control method according to the present invention includes calculating an estimated friction circle on the basis of longitudinal and lateral accelerations of a vehicle, limiting a drive force of the vehicle depending on a size of the estimated friction circle, and limiting a change rate of the size of the estimated friction circle during vehicle traveling on the basis of a tire generation force. The method further the change rate as the tire generation force increases.
US11845456B2 System, method, and apparatus for managing vehicle automation
A system including a vehicle having a network comprising a plurality of end points and a controller, where the controller includes an automation definition circuit, an automation management circuit, and an automation execution circuit. The automation definition circuit is structured to interpret an automation trigger description and an automation action description. The automation management circuit is structured to provide a trigger detection plan and an automated action plan in response to the automation trigger description and the automation action description. The automation execution circuit is structured to determine a trigger event value in response to the trigger detection plan, and to provide an automation command in response to the trigger event value and the automated action plan, where an end point of the plurality of end points is responsive to the automation command to implement an automated vehicle response.
US11845454B2 Operational envelope detection with situational assessment
Embodiments for operational envelope detection (OED) with situational assessment are disclosed. Embodiments herein relate to an operational envelope detector that is configured to receive, as inputs, information related to sensors of the system and information related to operational design domain (ODD) requirements. The OED then compares the information related to sensors of the system to the information related to the ODD requirements, and identifies whether the system is operating within its ODD or whether a remedial action is appropriate to adjust the ODD requirements based on the current sensor information. Other embodiments are described and/or claimed.
US11845451B2 Automobile diagnostic method, apparatus, device and system, and diagnostic connection device
Embodiments of the present invention relate to automobile diagnostic methods, apparatuses, devices and systems, and a diagnostic connection devices. Embodiments include: a first interface connector module configured to read an operation performed by a user on an interface, and convert the operation into a corresponding diagnostic instruction; a first protocol converting module configured to convert the diagnostic instruction into standard transmission data corresponding to the diagnostic instruction; and a first software interface module configured to send the standard transmission data corresponding to the diagnostic instruction through the first communication unit. Further embodiments include protocol conversion between a physical layer and a data link layer that consumes memory resources and processor resources is totally or partially run on the automobile diagnostic device, allowing the diagnostic connection device to only partially (or not at all) run the protocol conversion between the physical layer and the data link layer.
US11845445B2 Vehicle rollover prevention warning method, device, storage medium, and vehicle
A method, a device, a storage medium and a vehicle for vehicle rollover prevention warning, wherein the method for vehicle rollover prevention warning includes: collecting vehicle body rollover state parameters; calculating a lateral-load transfer rate of the vehicle according to the collected vehicle body rollover state parameters and a preset load transfer rate threshold model comprising the centrifugal force rollover moment of the sprung mass; and determining whether the vehicle has the risk of rollover or not according to the calculated lateral-load transfer rate and the preset rollover threshold. According to the technical solution provided by the invention, the load transfer rate threshold model based on the centrifugal force rollover moment of the sprung mass can simulate the actual rollover state of a vehicle more truly, with a more accurate state indication effect and a high warning accuracy.
US11845441B2 Speed based hands-on alarm system for a steering wheel
A speed based alarm system to be used in automobiles includes a first touch sensor, a second touch sensor, a processing unit, and a notification alarm. The first touch sensor and the second touch sensor are integrated into a steering wheel body of an automobile to detect the hands of the driver on the steering wheel. The feedback from the first touch sensor and/or the second touch sensor are received at the processing unit along with a vehicle speed, wherein the vehicle speed is retrieved from a vehicle logic board. The processing unit determines if the automobile is at a speed which requires both hands of the driver for better control of the automobile. If the automobile is at a speed that requires both hands of the driver, and only one hand is detected on the steering wheel, the processing unit activates the notification alarm to notify the driver.
US11845440B2 Contactless detection and monitoring system of vital signs of vehicle occupants
Disclosed are methods and systems for detecting vital signs of occupants in vehicles, for example, the vehicle cabin. A signal unit transmits a radar signal to the occupant and receiving the radar signal reflected from the occupant. The reflected radar signal is analyzed with respect to vibration data of the vehicle, to produce a modified signal. The modified signal is analyzed to determine the vital signs of the occupant.
US11845427B2 Hybrid vehicle and stability control method for the same
A stability control method of a vehicle includes: determining possibility of broadside collision; as a result of the determining, when the possibility of broadside collision is present, applying a standby hydraulic pressure to a hydraulic brake device; when broadside collision is detected, performing evasion steering using the hydraulic brake device in consideration of a direction of the broadside collision; and performing stability control after the evasion steering is performed.
US11845426B2 Movable carrier auxiliary system and parking auxiliary method thereof
A movable carrier auxiliary system includes an environmental detecting device, a control device, a state detecting device, and a parking auxiliary device. The environmental detecting device includes an image capturing module and an operation module. A parking auxiliary method thereof includes capture an environmental image around a movable carrier with the image capturing module; analyze whether the environmental image has a parking space with the operation module; detect a movement state of the movable carrier with the state detecting device; generate a prompting message with the parking auxiliary device based on an analysis result of the operation module and the movement state of the movable carrier, thereby the driver could manipulate the control device based on the prompting message to move the movable carrier to the parking space, improving a convenience and a safety when parking the movable carrier.
US11845423B2 Turning control system of vehicle and turning control method thereof
A turning control system of a vehicle includes: a database storing road information; a sensor part to detect a steering angle of a vehicle, a wheel speed of the vehicle, whether the vehicle is accelerated, whether the vehicle is braking, and whether a speed gear of the vehicle is shifted; and a controller that determines whether the vehicle enters a turning section based on one or more pieces of the information detected by the sensor part and the road information stored in the database. In particular, when the vehicle is entering the turning section, the controller sets a target speed of the vehicle and controls a speed of the vehicle to be decelerated to the set target speed.
US11845422B2 Path tracking control for self-driving of vehicle with yaw moment distribution
A method includes determining a desired yaw moment to be applied to an ego vehicle during travel. The method also includes identifying yaw moment changes that are achievable using different torque vectoring techniques supported by the ego vehicle. The method further includes selecting at least one of the torque vectoring techniques based on the identified yaw moment changes. In addition, the method includes using the at least one selected torque vectoring technique to obtain the desired yaw moment and create lateral movement of the ego vehicle during the travel. In some cases, a desired response time associated with the lateral movement of the ego vehicle may be used, where steering control provides a faster response time and torque vectoring control provides a slower response time. The at least one torque vectoring technique may be selected based on different energy efficiencies associated with different ones of the torque vectoring techniques.
US11845420B2 Methods and systems for coordinated shaping of HEV base torque
A vehicle operating method comprising generating a base torque reserve for an engine based on a position of an accelerator pedal and a position rate of change of the accelerator pedal, where the base torque reserve is an air reserve of the engine generated by the engine. The base torque reserve may further be generated based on one or more of a drive mode, a vehicle altitude, a battery state of charge (SOC), and a transmission gear, in at least one example.
US11845419B2 Apparatuses, methods and systems for controlling vehicles with engine start-stop, cylinder deactivation, and neutral-at-stop capabilities
An electronic control system controls operation of a vehicle system by selectably controlling the vehicle system using engine start-stop controls in response to one or more engine start-stop conditions being met, controlling the vehicle system using neutral-at-stop controls in response to one or more neutral-at-stop conditions being met, and controlling the vehicle system using cylinder deactivation controls in response to the one or more neutral-at-stop conditions not being met.
US11845412B2 Electromagnetic brake system
Disclosed herein is an electromagnetic brake system. The electromagnetic brake system includes a brake disc configured to be rotated together with a drive shaft of a drive motor configured to operate a vehicle wheel, an armature disc configured to be movable so as to be in close contact with or so as to be separated from one side of the brake disc, an elastic member configured to elastically press the armature disc to the one side of the brake disc to a direction in which the armature disc is in close contact with the brake disc, and an inductor configured to separate the armature disc from the brake disc by an electrical signal. The brake disc includes a tube portion mounted on the drive shaft, and a plate portion provided to extend in an outward direction of the tube portion to be opposite to the armature disc. The tube portion and the plate portion are provided as a single member in which the tube portion and the plate portion are integrally formed with each other.
US11845409B2 Method for inflating a tyre
A method for inflating a tyre mounted on a corresponding wheel rim comprises the following steps in sequence; placing a tool at an operating position, where a first bead of the tyre is interposed between the tool and a second bead of the tyre, and one end of tool is positioned axially between a first flange of the rim and a first rib of the rim and positioned radially between an outside surface of the rim and a tread of the tyre; blowing a gas under pressure through an inflation valve of the tyre into a chamber delimited by the tyre and by the rim, with the tool at the operating position, so that the first sidewall of the tyre is pressed against the end of the tool; removing the tool from the operating position.
US11845407B1 Cart cleaning machine
A cart cleaning machine has a foundation, a dock, a movable gantry, and a bellow assembly. The foundation has a cart path spanning the length of the foundation between a first end and a second end. Two side channels are also provided. A dock is stationarily mounted to the foundation. The dock has the shape of an inverted U to allow carts to pass through. The dock has a controller, a water inlet, an electrical hookup, a chemical station, and line management devices. The movable gantry is movable with respect to the foundation. It has a drive mechanism with sprockets that interact with bands spanning between the foundation ends. The gantry has spray nozzles and blow off openings. The bellow assembly is between the dock and the gantry. Water and electric lines pass through the bellow assembly and span between the dock and movable gantry.
US11845404B2 Adapter for connecting a windshield wiper to a drive arm of a wiper system for a motor vehicle
The invention relates to an adapter intended to connect a wiper blade (7) to a drive arm (5) of a wiper system (800) for a vehicle, the adapter (IO0) comprising a head (I) and a body (2), the adapter (IO0) being formed by an upper wall (IO, 20) and two lateral flanks (I la, I lb, 2la, 2lb), the adapter (IO0) comprising a centring means (3) for centring in a vertical direction (Oz) perpendicular to the upper wall (IO, 20), characterised in that the centring means (3) is extended longitudinally by a guide member (9) configured to be engaged with the drive arm (5), the adapter (IO0) comprising a tab (4) configured to wedge the adapter (IO0) in the vertical direction (Oz). The invention is applicable to motor vehicles.
US11845399B2 Recording video of an operator and a surrounding visual field
Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.
US11845395B2 Multi-point restraint system for an occupant seat mounted in a motor vehicle
A motor vehicle, seat and multi-point restraint system combination may include one or a combination of means for selectively preventing forward pivoting of the seat, one or more web attenuators for dampen forces applied thereby by one or more respective shoulder webs of the multi-point restraint system, at least one sleeve received on at least one shoulder web and a corresponding sleeve adjuster for adjusting a position of the sleeve along the respective shoulder web, web retractors operatively coupled to each of a pair of lap webs and to each of a pair of thigh webs of the multi-point restraint system, and at least one web retractor operatively coupled to the shoulder webs of the multi-point restraint system.
US11845393B2 Far-side airbag device
The far side airbag system has an airbag which is deployed and inflated between adjacent vehicle seats arranged side-by-side in the width direction when an impact is detected against one of a pair of side wall portions of the vehicle. The airbag includes an upper inflation portion having a portion deployed and inflated on a lateral side of a head portion of an occupant seated in the vehicle seat on a side farther from the specific side wall portion, and a lower inflation portion in which a portion including at least a lower end of the lower inflation portion is deployed and inflated between a console box arranged between the adjacent vehicle seats and the occupant. In the upper inflation portion, the portion positioned on the lateral side of the head portion is deployed and inflated such that a dimension in the width direction increases toward a front side.
US11845391B2 Emergency escape system and emergency escape method for vehicle
An emergency escape system and an emergency escape method for a vehicle are provided. The emergency escape system includes a sunroof that is mounted at a headliner of the vehicle and a driving device opening or closing the sunroof by receiving current. A float sensor detects whether the vehicle is filled with water up to a predetermined mounting position. A pressure sensor detects a force applied to the headliner or the sunroof. A controller supplies the current to the driving device in response to receiving from the float sensor a signal indicating that the vehicle is filled with the water up to the predetermined mounting position and determining that the force applied to the headliner or the sunroof, which is detected by the pressure sensor, is greater than a predetermined force.
US11845388B2 AC electrical power system for a vehicle
An AC electrical system for a vehicle and methods of operating the same are provided. In one aspect, an AC electrical system includes a first electric machine mechanically coupled with a first spool of a gas turbine engine and a second electric machine mechanically coupled with a second spool of the gas turbine engine. The system also includes a first AC bus and a second AC bus. A first electrical channel electrically couples the first electric machine to the first AC bus and a second electrical channel electrically couples the second electric machine to the second AC bus. The system also includes one or more connection links and one or more power converters for selectively electrically coupling the first and second electrical channels so that electrical power generated by one electric machine can be converted and shared with the other electric machine and electrical loads of the other channel.
US11845383B2 Exterior rearview mirror with power extending mechanism
A vehicular exterior rearview mirror assembly includes a mirror head having a mirror reflective element, a support structure configured for attachment at a side of a vehicle, and an adjustment mechanism operable to move the mirror head relative to the support structure between a retracted position and an extended position. A shutoff module includes a body and a plunger movably disposed at the body. The body is attached at one of the mirror head or the support structure and an outer end of the plunger is attached at the other of the mirror head or the body. As the mirror head moves relative to the support structure, an inner end of the plunger moves relative to and along a circuit element of the body. The adjustment mechanism is deactivated responsive to the inner end of the plunger reaching either end of the circuit element.
US11845380B2 Passenger safeguards for autonomous vehicles
Systems, methods, and computer-readable media are provided for detecting whether an object is approaching an autonomous vehicle when a passenger is about to exit the autonomous vehicle, determining a speed and type of the object that is approaching the autonomous vehicle, determining whether the object will enter an exit zone when the passenger enters the exit zone based on the speed and the type of the object that is approaching the autonomous vehicle, and preventing the passenger from exiting the autonomous vehicle based on the determining of whether the object will enter the exit zone when the passenger enters the exit zone.
US11845376B2 Radar and light emission assembly for vehicles for emitting light and radar radiation, and method and use
Provided is a radar and light emission assembly for emitting light and radar radiation and for detecting at least reflected radar radiation including: a headlight including a light-transparent headlight cover, and a light source, and a light reflector; a radar module, which is arranged behind the headlight cover, integrated in the headlight and including a radar antenna unit. The radar and light emission assembly has at least one radar radiation-forming mechanism, in particular a frequency-selective radar radiation-forming mechanism, including a radar radiation-forming mechanism, which is integrated in the headlight cover. The application of the radar technology, integrated in the headlight, can be further optimized hereby. The invention further relates to a method and a use for a radar and light emission assembly of this type.
US11845374B2 Loading system and method for laterally loading and unloading an upper body structure onto and from a vehicle platform of a motor vehicle
A loading system laterally loads and unloads an upper body structure onto a vehicle platform of a motor vehicle. The system includes two loading arms pivotably mounted on lengthwise ends of the vehicle platform. The loading arms jointly swivel between upward and lateral orientations with respect to the vehicle platform and jointly extend and retract. Each loading arm has an engaging portion at a distal end of the respective loading arm to engage a corresponding support portion at a respective lengthwise end of the upper body structure. The loading arms engage and release the upper body structure by swiveling into the lateral orientation and extending and retracting within the lateral orientation. The loading arms mount the engaged upper body structure on top of the vehicle platform by swiveling with the engaged upper body structure into the upward orientation and retracting with the engaged upper body structure within the upward orientation.
US11845372B2 Transport vehicle
A transport vehicle includes a pair of left and right vehicle body frames extending in a front and back direction; driving wheels disposed at a middle portion in the front and back direction of the pair of left and right vehicle body frames; auxiliary wheels disposed at a lower portion of an end portion in the front and back direction of each of the right and left vehicle body frames; lifter mechanisms disposed at an upper portion of an end portion in the front and back direction of each of the right and left vehicle body frames; a connection frame connecting upper portions of the right and left vehicle body frames to each other; and a lower frame disposable between the right and left vehicle body frames, the lower frame being removably fixed at lower portions of the right and left vehicle body frames.
US11845371B2 Vehicle seat
A seatback and/or a seat cushion has left and right side frames arranged spaced apart in a left-right direction, and wire laid between the left and right side frames. The wire extends substantially in parallel to the side frames. A pad is placed on the side frames and the wire. The pad includes a first pad layer on the side of a seating surface, and a second pad layer on a side of the pad opposite to the seating surface. The second pad layer is harder than the first pad layer. The second lad layer is supported while being in contact with the side frames and the wire.
US11845368B2 Vehicle seat comprising a temperature-control system
A vehicle seat includes a temperature-control system which is connectable or connected to a temperature-control circuit that conveys a temperature-control medium. The vehicle seat includes at least one temperature-control heat exchanger by which thermal energy can be delivered to and/or absorbed from the environment using the temperature-control medium. The vehicle seat includes at least one electrically operable or electrically operated temperature-control element which is a heating and/or cooling element.
US11845367B2 Recliner heart having lubricant member
A recliner heart may include a first locking plate, a second locking plate, a cam and a lubricant member. The first locking plate includes an outer diametrical surface having first teeth formed thereon. The second locking plate is rotatable relative to the first locking plate and includes an inner diametrical surface having second teeth formed thereon. Some of the second teeth are meshingly engaged with some of the first teeth. The cam is connected to the second locking plate and includes a groove formed therein. The lubricant member is disposed in the groove of the cam.
US11845363B2 Autonomous vehicle adapted for sleeping or resting in a reclined posture
A vehicle has an automatically tiltable seat, a plurality of seat actuators fully supporting the automatically-tiltable seat to enable the automatically tiltable seat to pitch or roll to compensate for motion of the vehicle, and a processor to predict the motion of the vehicle and to control the plurality of seat actuators. The plurality of seat actuators automatically adjust the pitch or roll of the automatically tiltable seat in response to the motion of the vehicle. The seat actuators also provide shock absorption.
US11845362B2 Seat system with output by touch operation of sensors
Provided is a seat system which can change a surrounding environment of a user including illumination according to the movement of the user's body. A seat system comprises a seat body on which a user can be seated; a plurality of sensors provided on or in the seat body or on a structure arranged around the seat body and configured to detect a touch operation by the user seated on the seat body; an output device configured to output at least one of sound, light, and vibration; and a control device configured to control the output device such that, when one or more of the sensors detect a touch operation, the control device causes the output device to generate a corresponding predetermined output.
US11845361B2 Electric vehicle including Rankine cycle
An electric vehicle including the Rankine cycle in which a circulation system of working fluid is formed is proposed. The Rankine cycle includes a pump configured to circulate the working fluid along the circulation system, a heat source comprising a battery unit, a motor unit, and a solar panel unit to transmit thermal energy to the working fluid circulated by the pump, a power generating unit provided on a path of the circulation system to generate electric energy through the thermal energy of the working fluid passing through the heat source, and a radiator configured to perform a heat exchange process between the working fluid passing through the power generating unit and outside air. The Rankine cycle further includes a flow distributor to distribute the working fluid circulated by the pump to at least any one of the battery unit, the motor unit, and the solar panel unit.
US11845358B2 Fuse management for an electric mobile application
A system including a vehicle having a motive electrical power path; a power distribution unit having a current protection circuit disposed in the motive electrical power path, the current protection circuit including: a first leg of the current protection circuit comprising a first pyro-fuse; a second leg of the current protection circuit comprising a thermal fuse in series arrangement with a second pyro-fuse; and where the first leg and the second leg are coupled in a parallel arrangement; a controller, including: a current detection circuit structured to determine a current flow through the motive electrical power path; and a pyro-fuse activation circuit structured to provide a pyro-fuse activation command in response to the current flow exceeding a threshold current flow value; and where at least one of the first pyro-fuse and the second pyro-fuse is responsive to the pyro-fuse activation command.
US11845352B2 Power supply control method for vehicle, vehicle, control unit and medium
The present disclosure relates to a power supply control method for a vehicle, a vehicle, a control unit, a computer-readable storage medium and a computer program product. The vehicle comprises an electrical equipment, a relay and a power interface, wherein the power interface is electrically coupled to the electrical equipment via the relay. The method comprises: determining whether the power interface is coupled to an external power source; determining whether a voltage of the external power source is within a predetermined range when the power interface is coupled to the external power source; and controlling the relay to be switched on in response to the voltage of the external power source being within the predetermined range.
US11845351B2 System and method for a mission-based battery status display for electric vehicles
Systems and methods are provided for displaying operating data for a re-chargeable battery for an electric vehicle. The system comprises a re-chargeable battery for powering components of an electrical vehicle, a sensor that detects a present level of charge in the battery and a display. The display receives the present level of charge of the battery from the monitor and displays the present level of charge in the battery, a required level of endurance for the battery that is based on a planned operational parameter for the vehicle, a minimum level of charge in the battery that meets the required level of endurance, and an amount of time needed to re-charge the battery to achieve the minimum level of charge.
US11845348B2 Charging plug for a motor vehicle, and load contact module for a charging plug
A charging plug for a motor vehicle, having a connection module and a load contact module, the connection module being connectable to supply lines for supplying power, the load contact module having a load contact for transmitting charging power, and the load contact module being detachably and replaceably secured to the connection module, the load contact module including a temperature sensor.
US11845347B2 Precision charging control of an untethered vehicle with a modular vehicle charging roadway
Methods and systems for precision charging control of an untethered vehicle include at least a wireless charging antenna carried by a vehicle and in electrical communication with a vehicle propulsion system. A plurality of wireless charging antennae is positioned on or within a roadway and are in communication with at least a roadway control system and a power source. An authentication connection is established between the vehicle wireless charging antenna and the roadway control system. A dynamic seek operation is triggered between the first wireless charging antenna and the one of the plurality of second wireless charging antennae to pair the first wireless charging antenna with the one of the plurality of second wireless charging antennae. A quantity of electrical energy is transferred between the first wireless charging antenna and the one of the plurality of second wireless charging antennae.
US11845338B2 Method for operating a piston engine, and piston engine
A method for operating an internal combustion engine. The method includes providing a piston engine. The piston engine includes a crankshaft and a torque sensor system. The torque sensor system includes at least one first rotary angle sensor and at least one second rotary angle sensor. The method further includes measuring a first and a second rotary angle in a spacing region and determining an angular offset between the first and the second rotary angle. The angular offset results from the torsion of the loaded crankshaft wherein the spacing region is limited along the crankshaft to an actual partial region of the spacing between the bearing journals. The partial region includes an actual subgroup of at least one of the number of offsets and the number of shaft journals, so that the angular offset is assigned to the actual subgroup.
US11845336B2 Powertrain for a hybrid vehicle
Disclosed is a powertrain for a hybrid vehicle including a first motor provided to be selectively connected to an engine, a second motor provided to be selectively connected to the first motor, and an output shaft provided to transfer the rotational force of the second motor to drive wheels of the vehicle.
US11845335B2 Image capture device and associated system for monitoring a driver
The invention relates to an image capture device (1) comprising an image sensor (9) making it possible to obtain both an infrared image (31) and an image in the visible range (35) by means of an array of optical filters comprising first filtering elements, having a transmission spectral band in the infrared range, as well as second filtering elements, having a transmission spectral band in the visible range. The image capture device further comprises: —a lighting device (11) configured to emit infrared radiation, and—a computer (13), programmed to control the power of the infrared radiation emitted by the lighting device, as a function of said ambient luminosity in the infrared range. The invention also relates to a monitoring system (2) for monitoring a driver (3), comprising such an image capture device.
US11845330B2 Reducer for electric vehicle
A reducer for an electric vehicle includes an input shaft connected to a motor, a differential disposed coaxially with the input shaft and relatively rotatable, a planetary gear train configured to decelerate power of the input shaft and transmit the power to a differential casing of the differential, and a drive shaft configured to penetrate the input shaft and coupled to one side gear of the differential.
US11845328B2 Electric drive unit with motor assembly isolated from beaming loads transmitted through housing assembly
An electric drive unit having an electric motor, a differential assembly, a transmission, which transmits rotary power between the electric motor and the differential assembly, a pair of axle shafts, which are drivingly coupled to output members of the differential assembly, and a housing assembly in which the electric motor, the differential assembly, the transmission, and the axle shafts are housed. The electric motor includes a stator, a rotor and a motor housing that houses the stator and the rotor. The motor housing is fixedly coupled the housing assembly. Bending loads transmitted through the motor housing are not transmitted through the electric motor.
US11845326B1 Flexible cover system
A flexible cover system includes a sheet of flexible material having a first face and a second face. Each receptacle from a set of receptacles has walls coupled to the sheet's first face. The walls extend away from the first face and terminate at an opening of the receptacle that resides in a plane that is parallel to the first face. The walls associated with each receptacle are separated from the walls associated with adjacent ones of the receptacles by an air-filled gap. Each body from a set of bodies is configured for retention in one of the receptacles by the walls associated therewith.
US11845323B2 Vehicle roof comprising a shading arrangement and guide rails
A vehicle roof having a plate-shaped body-shell element and a shading arrangement which has a shading element and guide rails for laterally guiding the shading element. At least one fixing element is formed integrally on each of the guide rails at an upper side facing the body-shell element, said fixing element being in engagement with at least one molded portion which is molded to the body-shell element and has at least one fixing counterpart.
US11845322B2 Conveying vehicle-related information using thermal touch and haptics
A portable display apparatus for conveying vehicle-related information using thermal and haptic touch is provided. The portable display apparatus includes circuitry communicatively coupled to a temperature control unit of the portable display apparatus. The circuitry receives from one or more first sensors associated with a vehicle, first temperature information associated with an interior space of the vehicle or an ambient environment of the vehicle and determines a temperature setting based on received first temperature information. The circuitry detects a physical-contact between the portable display apparatus and one of a skin portion or a cloth portion worn by a user. Thereafter, the circuitry controls the temperature control unit based on the determined temperature setting and the detected physical-contact. The temperature control unit is controlled to change a current temperature of at least a first section of the portable display apparatus to a first temperature, which is different from the current temperature.
US11845321B2 Vehicle thermal management at condensers of the refrigerant loop
Thermal management in a vehicle involves a compressor to output a refrigerant in vapor form for circulation in a refrigerant loop. A thermal management system includes a heating, ventilation, and air conditioning system in the refrigerant loop including an evaporator and an HVAC condenser, and an exterior condenser in the refrigerant loop configured to vent heat to an exterior of the vehicle. A first variable refrigerant flow valve controls a flow rate of the refrigerant output by the compressor into the HVAC condenser, and a second refrigerant flow valve controls a flow rate of the refrigerant output by the compressor into the exterior condenser. A controller controls the first refrigerant flow valve and the second refrigerant flow valve based on a target output temperature for the HVAC condenser.
US11845320B2 Apparatus and method for controlling air conditioning of vehicle
An air conditioning control apparatus for a vehicle according to the present disclosure includes a sensor that senses a number of vehicle occupants, a vehicle speed, and an indoor temperature and an outdoor temperature of the vehicle, an air conditioner that adjusts an amount of air introduced from an outside or exhausted to the outside, and a controller that controls the air conditioner based on the number of vehicle occupants, the vehicle speed, and the indoor temperature and the outdoor temperature of the vehicle. According to the present embodiment, the comfort inside the vehicle may be improved by adjusting the ventilation amount depending on the number of vehicle occupants, the vehicle speed, and the indoor temperature and the outdoor temperature of the vehicle.
US11845316B1 Adjustable pivot joint for vehicle suspensions
A pivot joint for connection between first and second suspension members in a vehicle suspension permits adjustment of wheel alignment characteristics without removal or disassembly of the pivot joint. Wheel alignment adjustment may be accomplished with mutual rotation of engaged components of the pivot joint, wherein engaged guide structures of the pivot joint component convert the mutual rotation to translational movement of one pivot joint component relative to the other pivot joint component. The translational movement may be oriented to selectively adjust wheel alignment characteristics.
US11845315B2 Intelligent power management while in camp mode
Some embodiments may provide a method for a desired operating environment. A signal to place a vehicle in a designated mode corresponding to a desired operating environment may be received. The designated mode may include modifications to one or more default operating characteristics of the vehicle. The modifications may be while the vehicle is in parked mode and a vehicle access key associated with the vehicle is within proximity of the vehicle. In response to receiving the signal, characteristics of the vehicle to be modified in order to create the desired operating environment may be identified. The default operating characteristics may relate to power-consuming features or available power for connected accessories. One or more settings of the vehicle to change the default operating characteristics of the vehicle while in the designated mode may be modified.
US11845312B2 Trailer chain safety device
A safety device for use with a chain extending between a trailer and a tow vehicle. The device has a central sleeve that houses the chain. Two side sleeves extend parallel to the central sleeve and house an elastic cord. The elastic cord provides tension to the sleeve, allowing the chain to group or bunch up without tension. The allows a user to avoid having to manipulate the length of the chain in order to avoid chain drag from the chains being too long or chain bind from the chains being too short when the vehicle attempts to turn while towing the trailer. Typically trailers have a pair of safety chains extending from the trailer to the vehicle, thus two of the devices are preferably utilized.
US11845310B2 Systems and methods for tire warmup and vehicle launch optimization
Methods and systems are provided for warming vehicle tires prior to a vehicle launch event. In one example, a method may include, in response to an initiation of a burn out event while locking non-driven wheel brakes, adjusting a spinning of driven wheels based on vehicle performance parameters measured during a previous vehicle launch. In this way, a vehicle controller may control the tire warming to increase tire traction while reducing tire wear.
US11845308B2 Tire emergency safety valve
A safety valve replaces a tire valve. The valve includes a generally elongate hollow main body having an upper portion, a lower flex hose connector, a side tubular branch having a valve seat with a ball valve, an electronics housing having a battery, motor and a drive pin for the ball valve. The lower flex hose connector is adapted for connection to a flex hose or valve stem of the vehicle tire. The side branch branches from the main body and communicates with the hollow interior of the main body. The side branch has a plurality of air exit apertures at its periphery. The valve seat includes a base with an aperture therein through which the drive pin can extend through to engage the ball valve. The ball valve sits in the base and is biased in the valve seat via a spring to cover the aperture.
US11845307B2 Device and method for detecting abnormal state of tire
A device for detecting an abnormal state of a tire includes a wireless transceiver spaced apart from the tire and coupled to a vehicle, where the wireless transceiver transmits a radio signal to a ground surface and acquires delay information required to receive a reflected wave from the ground surface, and a control module that calculates a reference distance between the wireless transceiver and the ground surface based on the delay information, and detects an abnormal state of the tire, based on a reference distance change.
US11845304B2 System and method for harvesting energy for an electronic device, and a tire configured for use with the same
A system for powering an electronic device within a tire is provided, the system comprising: a generator; an electrically conductive wheel coated in a non-conductive coating, the wheel including rim lips, wherein one of the rim lips includes a conductive area; the tire including bead portions, sidewalls, shoulders, a tread oriented in a tread region, and an inner surface; a conductive element extending from a bead portion, and in contact with the inner surface; an electronic device within the vehicle tire; and a ground path extending through a thickness of the vehicle tire from the inner surface to an exterior surface in a contact patch of the tread; wherein the generator is electrically connected to the electrically conductive wheel; wherein the electronic device is electrically connected to the conductive element and the ground path; and wherein the conducive element contacts the conductive area.
US11845303B2 Tread structure of an agricultural vehicle tire
Agricultural vehicle tire having tread (1) with bearing surface (10) on which main lugs (3) and shorter secondary lugs (3) are formed on each side of the equatorial mid-plane (XX′), each secondary lug (3) interposed between two main lugs (2). The main lugs (2) and secondary lugs (3) make up, in the radial direction, a lens (21, 31) of a first material, each lens (21, 31) surmounted by a second material extending to the contact face of the main lugs and the secondary lugs. The viscous modulus G′1 of the first material is at most 60% of the viscous modulus G′2 of the second material. The complex modulus G′1 of the first material differs from the complex modulus G′2 of the second material, the difference between these complex moduli being at most 30% of the complex modulus G′2 of the second material.
US11845301B2 Aero ring inserts for wheel aerodynamics
An air deflection ring that is configured to be attached to a wheel of a motor vehicle that includes a barrel including a cylindrical inner surface and an opposing cylindrical outer surface, a plurality of spokes that are each separated by an opening and attach the barrel to a center of the wheel. The air deflection ring includes a cylindrical mounting ring that is configured to be fixed to the cylindrical inner surface of the barrel, and an air deflection flange that extends radially inwardly toward the center of the wheel from the cylindrical mounting ring. The cylindrical mounting ring is configured to be fixed to the cylindrical inner surface of the barrel at a location positioned immediately adjacent to the plurality of spokes, and the air deflection flange is configured to direct a flow of air away from the openings during rotation of the wheel.
US11845300B2 Rim with recessed channel and rim strip apparatus and system
A vehicle wheel rim including: a tire bed surface having laterally spaced first and second bead seats that are configured to support respective first and second beads of a mating tire; and a rim well laterally positioned between the first and said second bead seats and including a circumferential first step edge; and a first lateral offset region laterally positioned between the first bead seat and the first step edge, with the first step edge extending radially inwardly from the first lateral offset region and configured to provide for lateral alignment registration and/or visual alignment and placement of a first edge of a mating rim strip. The rim strip is a circumferential element that radially outwardly overlaps the rim well and extends laterally inwardly from the first step edge. The first step edge is radially inboard of the first bead seat.
US11845295B2 Printable medium
A printable medium with a non-woven base composite supporting substrate; at least two coating layers, on the image side of the composite supporting substrate, that include an ink fixing layer, directly applied upon the supporting substrate, comprising a salt; and an image receiving layer, applied over the ink fixing layer, including pigment fillers and polymeric binders; and a barrier layer, containing a flame-retardant agent, applied on the backside of the composite supporting substrate. Also disclosed are the method for producing printed images using said media and the resulting printed material.
US11845293B2 Printing device performing printing operations on continuous medium including a plurality of print media each having information storage medium
In a printing device, a controller is configured to perform: (a) writing; (b) printing; (c) determining; (d) conveying; (e) writing; (f) printing; and (g) writing. The (a) writing writes prescribed information to an information storage medium provided in a first print medium. The (b) printing prints a prescribed image on the first print medium. In response to determining in (c) that the printing quality of the prescribed image is not good for the first print medium, the (d) conveying conveys a continuous medium in a reverse direction, the (e) writing writes void information to the information storage medium provided in the first print medium, the (f) printing prints a VOID image on the first print medium after the (e) writing is performed, and the (g) writing writes the prescribed information to the information storage medium provided in a second print medium prior to performing the (f) printing.
US11845288B2 Flow path unit and liquid ejecting device
Provided is a flow path unit through which liquid to be supplied to a head for ejecting the liquid flows. The flow path unit includes a flow path member having a flow path, and a filter unit configured to be detachably attached to the flow path member, the flow path member has an opening that communicates with the flow path and to which the filter unit is configured to be mounted, and the filter unit includes a filter configured to filter liquid flowing through the flow path, and a holding member configured to hold the filter.
US11845283B2 Liquid ejecting apparatus and method for controlling liquid ejecting apparatus
A liquid ejecting apparatus includes a liquid ejecting portion configured to eject a liquid, a liquid collection device including a band-shaped member configured to come into contact with the liquid ejecting portion to wipe a liquid attached to the liquid ejecting portion, and a winding portion configured to wind up the band-shaped member, a temperature/humidity sensor configured to acquire temperature/humidity information related to a temperature and a humidity around the liquid collection device, and a control portion configured to cause the band-shaped member to come into contact with the liquid ejecting portion to wipe the liquid, and then cause the winding portion to wind up the band-shaped member. The control portion determines, based on the temperature/humidity information acquired by the temperature/humidity sensor, a winding length of the band-shaped member wound by the winding portion after the band-shaped member wipes the liquid.
US11845282B2 Liquid accommodating body and liquid ejecting apparatus
A liquid accommodating body is detachably mounted on a mounting portion having a waste liquid flow-out portion for discharging a waste liquid, and a liquid flow-in portion. The liquid accommodating body includes a waste liquid flow-in portion that is coupled to the waste liquid flow-out portion when the liquid accommodating body is mounted on the mounting portion, and a waste liquid accommodating portion configured to accommodate the waste liquid discharged from the waste liquid flow-out portion. Further, the liquid accommodating body includes a liquid flow-out portion that is coupled to the liquid flow-in portion when the liquid accommodating body is mounted on the mounting portion, and an adjusting water accommodating portion configured to accommodate adjusting water.
US11845281B2 Liquid ejection head
A liquid ejection head includes an ejection orifice for ejecting a liquid; a substrate on which an energy-generating element and an insulating layer are formed on a first surface; a liquid inflow path which penetrates the substrate and makes a liquid flow in a flow path disposed between the ejection orifice and the element; and a liquid outflow path which penetrates the substrate and makes the liquid flow out of the flow path. The liquid inflow path and the liquid outflow path have a first opening and a second opening penetrating the insulating layer on the first surface of the substrate, the ejection orifice is disposed between the liquid inflow path and the liquid outflow path, and an ejection orifice side end of the second opening is formed closer to the ejection orifice than an ejection orifice side end of the first opening.
US11845277B2 Inkjet head, method of manufacturing inkjet head, and inkjet recording method
Provided is an inkjet head containing a nozzle plate having at least a substrate, wherein the nozzle plate has a liquid-repellent layer on an outermost surface of the substrate on an ink ejection surface side; a liquid-repellent layer base film is provided between the substrate and the liquid-repellent layer; and the liquid-repellent layer base film contains at least silicon (Si) and carbon (C), and having a maximum peak P of a binding energy of a Si2p orbital of a surface portion measured by X-ray photoelectron spectroscopy is in the range represented by the following Formula (1), Formula (1): 99.6 (eV)≤P≤101.9 (eV).
US11845276B2 Inkjet head and method of ejecting ink using the same
Disclosed is an inkjet head and a method of ejecting an ink using the same. An inkjet head according to one embodiment of the present invention may include nozzles each including a ejecting hole through which a solution including a light-emitting element is ejected and pairs of electrodes which are provided around the ejecting holes to face each other and which apply an electrode voltage to the light-emitting element.
US11845272B2 Liquid jet head and liquid jet recording device
A liquid jet head and so on capable of enhancing the convenience while improving the performance are provided. The liquid jet head according to an embodiment of the present disclosure includes a jet section configured to jet liquid, at least one drive device which applies a drive signal having a predetermined drive waveform to the jet section to thereby cause the jet section to jet the liquid, and a waveform setting section configured to generate regular waveform configuration information for setting the drive waveform based on simplified waveform configuration information supplied from an outside of the liquid jet head. The waveform setting section converts the simplified waveform configuration information including at least one type of reference potential value set along a time axis into the regular waveform configuration information including a plurality of types of power supply potential values set for each of the reference potential values to thereby generate the regular waveform configuration information based on the simplified waveform configuration information.
US11845264B2 Recording device
A recessed portion is a portion that is provided to an end of a platen in an X direction and is recessed from the supporting surface of the platen. A discharge portion discharges the ink in the recessed portion along a +Y direction. A width of the discharge portion in an X direction is smaller than a width of the recessed portion in the X direction, and a position of the discharge portion in the X direction is arranged on an inner side with respect to a position of an edge of the roll paper. An end side of the discharge path, which is positioned on an inner side of the roll paper in the X direction, is arranged continuously to an end side of the recessed portion, which is positioned on the inner side of the roll paper, on an extension line of the end side.
US11845261B2 Bag puller release post printing process
A releasing system for a printing machine includes a pallet configured to support a substrate for receiving indicia printed thereon. A layer is disposed intermediate the pallet and the substrate. A releasing station selectively stretches the layer to release a surface of the substrate from a state of adhesion with the pallet.
US11845253B2 Systems and methods of apparel manufacturing using adhesive bonding
Embodiments include methods of making a fabric laminates including depositing a first and a second columns of discrete adhesive masses on a first layer of fabric, wherein the first and second columns of discrete adhesive masses are separated by a first gap area, and placing a second layer of fabric on the first layer of fabric sandwiching the first and second columns of discrete adhesive masses, and applying pressure to all layers to form a fabric laminate structure while maintaining the first gap area unobstructed and forming a tunnel area between the first gap area and the first and second fabric layers. In some embodiments, ribbons may be pulled through the tunnels. In some embodiments, the tunnels include batting material. In some embodiments, films are placed on the first or second fabric layer and they imprint their surface finish onto the discrete adhesive masses wetting the surface of the fabric layers.
US11845247B2 Composition for laminated material used for medical lubricating member, laminated material used for medical lubricating member, medical lubricating member, medical device, and method for producing laminated material used for medical lubricating member
There is provided a composition for a laminated material used for a medical lubricating member, the composition including a polymer b including a polysiloxane structure, a catalyst for crosslinking reaction, and a crosslinking agent having a particular structure. The polymer b includes at least one of an acrylic acid component, an acrylic acid ester component, an acrylamide component, or a styrene component and has a hydroxy group, a carboxy group, an amino group, an isocyanate group, an oxazolinyl group, an epoxy group, a vinyl group, an ethynyl group, a sulfanyl group, an azide group, a trialkoxysilyl group, or an acid anhydride structure. There are also provided a laminated material and a medical lubricating member produced from the composition, a medical device including the laminated material and the medical lubricating member, and a method for producing the laminated material and the medical lubricating member.
US11845244B2 Inline coated biaxially oriented polyethylene foil and method for the production thereof
A biaxially oriented polyethylene foil (BOPE) is disclosed having layers (A) to (D), wherein layers (B) to (D) contain biaxially oriented polyethylene and layer (A) contains polyurethane and nanoparticles and has a layer thickness of 25 to 300 nm, layer (B) includes polymers having functional groups which are capable of forming covalent bonds with polyurethane and are directly connected to layer (A), layer (C) has at least a layer thickness of 50% of the total thickness of the foil and layer (D) represents an outer layer of the foil, which contains antiblocking agents.
US11845242B2 Multilayer film
A multilayer film includes a first skin layer, a second skin layer, and a core layer. The core layer includes at least two lanes of material. Each of the lanes of material of the core layer contacts each of the first skin layer and the second skin layer.
US11845241B2 Laminate containing an adhesion promoter layer and method of making the laminate
A laminate can contain a substrate, an adhesion promoter layer, and a coating layer, wherein the adhesion promoter layer may include an isocyanate group containing compound of formula (1): R1—R2—N═C═O (1), with R1 being a functional group different than the isocyanate group, and R2 being substituted or unsubstituted alkyl or aryl. The adhesion promoter layer can provide strong adhesion of the coating layer to the substrate by forming covalent bonds with the substrate and covalent bonds with the coating layer.
US11845239B1 Mobile dismantling system for dismantling solar cell module
A mobile dismantling system includes an automatic frame dismantling apparatus, a fragmenting apparatus, and a conveying apparatus, all of which are disposed on a mobile apparatus, such as a wheeled transport vehicle. The automatic frame dismantling apparatus includes a dismantling platform and frame dismantling members. The fragmenting apparatus includes a back plate fragmenting device and a cell encapsulation laminate fragmenting device, each of which has a fragmenting platform, a fragmenting unit, and a material collecting and sorting device. The conveying apparatus is disposed above the automatic frame dismantling apparatus and the fragmenting apparatus, and includes a robot for moving solar cell module.
US11845238B2 Sound damping gypsum board and method of constructing a sound damping gypsum board
The present invention is directed to an improved gypsum board, such as an improved sound damping gypsum board. The gypsum board comprises a gypsum core including gypsum and a sound damping polymer. The gypsum core includes a first gypsum layer surface and a second gypsum layer surface opposing the first gypsum layer surface. In addition, a first encasing layer is disposed on the first gypsum layer surface and a second encasing layer is disposed on the second gypsum layer surface.
US11845236B2 Composite structure splice and method
A method for fabricating a composite structure. A first section for the composite structure is formed in which the first section has a first end with a chevron shape, wherein first composite layers in the first section has a first step pattern at the first end. A second section for the composite structure is formed in which the second section has a second end with a counterpart shape to the chevron shape and in which second composite layers in the second section have a second step pattern at the second end. The first end the second end are positioned such that a first composite layer in the first composite layers in the first step pattern overlap the second composite layers in the second step pattern at a splice location.
US11845233B1 Precision tow impregnation manufacturing system
A simple, cost effective Precision Shaped Tow Manufacturing system can produce high tolerance, dimensionally accurate, ready to use, Unidirectional Resin Impregnated Fiber Tow, Shaped Tow, in one procedure by a single machine that is precise enough to support Automatic Fiber Placement, AFP and Automatic Tape Laying specifications, ATL. The tow shaping system may include a Rotating Forming System, a Static Forming System, or both. A flash cooling chiller is provided to instantaneously set the tow to lock in the shape with a high tolerance.
US11845230B2 Profile connection
A connection includes: a first profile having a first end, the first profile including a first polymeric material comprising a thermoset material; and a second profile having a second end, the second profile including a second polymeric material, a metal, or combination thereof, wherein the first end and the second end are coincidently bonded without a bonding material at an interface of the first end and the second end.
US11845229B2 Techniques for additive fabrication process optimization and related systems and methods
According to some aspects, a method of additive fabrication is provided wherein a plurality of layers are formed on a build platform, each layer contacting a container in addition to the build platform and/or a previously formed layer, the method comprising calculating, using at least one processor, one or more forces to be applied to a first layer of the plurality of layers subsequent to the first layer being formed, said calculating being based at least in part on a determined area of at least one portion of the first layer that overhangs a second layer of the plurality of layers, forming the first layer, the first layer being in contact with the container and in contact with a previously formed layer of the plurality of layers, and separating the first layer from the container by applying the calculated one or more forces to the first layer.
US11845224B2 Additive manufacturing methods and systems for detection and extraction of impurities
An additive manufacturing system for extraction of impurities in additive manufacturing material, the system including an additive manufacturing machine for manufacturing a part using additive manufacturing material. The system may additionally include a conductive plate adjacent to the additive manufacturing material. The system can further include an energy source for distributing an electric charge through the conductive plate adjacent to the additive manufacturing material. Distributing the electric charge through the conductive plate can attract impurities from the additive manufacturing material to the conductive plate.
US11845223B2 Apparatus, system and method of operating an additive manufacturing nozzle
Apparatuses, systems and methods of providing heat to enable an FDM additive manufacturing nozzle having refined print control and enhanced printing speed. The heating element may include at least one sheath sized to fittedly engage around an outer circumference of the FDM printer nozzle; at least one wire coil at least partially contacting an inner diameter of the sheath; and at least one energy receiver associated with the at least one wire coil.
US11845221B2 Method of thermally transferring layers in a selective deposition-based additive manufacturing system using conductive heat
Disclosed are selective deposition-based additive manufacturing systems (10) and methods for printing a 3D part (26). Layers of a powder material (22) are developed using one or more electrostatographic engines (12a-d). The layers (22) are transferred for deposition on a part build surface (88). For each of the layers (22), the part build surface (88) is pre-heated by impinging a first heat transfer liquid (74) toward the part build surface (88), for example using a solder fountain. The developed layer (22) is pressed into contact with the heated part build surface (88) to heat the developed layer (22) to a flowable state and form a new part build surface (88) which is fully consolidated. The new part build surface (88) is then rapidly cooled to remove the heat energy added during heating step before repeating the steps for the next developed layer (22).
US11845216B2 3D printed electronics using directional plasma jet
A device and method for printing 3D articles including electronic and functional elements including 3D printer and a plasma jet printer based on a dielectric barrier atmospheric pressure plasma jet system in which both printing and in-situ treatment and post-deposition treatment can be carried out to tailor the materials characteristics. Plasma jet printer comprising of electrodes in the nozzle/print head for applying electric field and generating atmospheric plasma that could be used for non-gravity based highly directional printing in any direction. Integration of dielectric barrier plasma printer and plasma treatment jets with the 3D printer increases the capability of embedding high performance electronics in a 3D printed structure aiding in additive manufacturing of functional devices. Ability to use a range of materials for print head assembly including micro machined silicon increases the resolution of the plasma jet printer to sub-micron level.
US11845215B2 Method for manufacturing three-dimensional shaped object and three-dimensional shaping device
A method for manufacturing a three-dimensional shaped object includes: a first step of forming a first portion of the three-dimensional shaped object by discharging a shaping material containing a resin from a discharge portion toward a stage or a previously formed layer and pressing the discharged shaping material against a tip end surface of the discharge portion; a heating step of heating the first portion to a temperature less than a glass transition temperature of the resin; and a second step of forming a second portion of the three-dimensional shaped object by discharging the shaping material from the discharge portion toward the first portion heated in the heating step and pressing the discharged shaping material against the tip end surface.
US11845214B2 Method and device for producing filled containers from preforms
A method for producing filled containers (16) from preforms (13). Each of the preforms is transferred to a circulating molding and filling element (14) of a molding and filling station and is shaped into the respective container in a subsequent molding and filling process in a mold under the effect of pressure from a supplied filler, wherein the mold is designed in multiple parts, including a base mold (21) and mold sides (19, 20), and each container is clamped between the base mold at the bottom and the molding and filling element at the top at least at the end of the molding and filling process. The container is separated from the respective molding and filling element and the respective mold after the molding and filling process. The mold sides are removed from each container before the molding and filling element and the base mold are separated from the container.
US11845212B2 Injection molding apparatus, cooling plate for injection molding apparatus, and cassette mold
An injection molding apparatus includes: a molding mold including a fixed mold in which a gate into which a molding material flows is formed, and a movable mold in which a cavity portion is formed and which is separated from the fixed mold when the mold is opened; a nozzle in which a flow path that guides the molding material to the gate is formed; and a first cooling plate which is detachably attached to an opposite-side surface of the movable mold from a surface to be in contact with the fixed mold and which is provided with a first cooling mechanism therein, and the first cooling mechanism cools the molding material in the cavity portion.
US11845205B2 Method for producing gear, gear, and bending meshing type gear device
Provided is a method for producing a gear including an intermediate product forming process of solidifying a fluid material to form a gear intermediate product, and a tooth forming process of cutting the gear intermediate product to form teeth.
US11845204B2 Elastic fastener for vacuum bag pleat
A vacuum bag having an expandable pleat is provided. The vacuum bag includes a first surface region, a second surface region, and a third surface region between the first and second surface regions. The third surface region can be folded to bring the first surface region into proximity of the second surface region. The vacuum bag also includes a strip having a first attaching region at a first end of the strip, a second attaching region at a second end of the strip opposite the first end, and a central region between the first and second attaching regions. The first attaching region is fixed to the first surface region, and the second attaching region is fixed to the second surface region such that when the central region of the strip is in a non-expanded state, the first surface region is contiguous to the second surface region.
US11845203B2 Compression molding device of parts in composite material starting from plates in composite with a thermoplastic matrix
A compression molding device configured for the production of a part in composite material starting from a plate in composite with a thermoplastic matrix is described. The device comprises: a fixed support structure; an upper half-die provided with a first contoured surface corresponding to the profile of an upper surface of the part to be made; a lower half-die provided with a second contoured surface corresponding to the profile of a lower surface of the part to be made; holding means carried by the support structure and configured to hold the plate in a position interposed between the half-dies; and moving means for moving at least one of the half-dies from and towards the plate. The holding means comprise two or more releasable grippers gripping by friction distinct portions of the peripheral edge of the plate and configured to completely release or allow the complete release of the plate.
US11845200B2 Low viscosity dual cure additive manufacturing resins
Provided herein according to some embodiments is a dual cure additive manufacturing resin, comprising: (i) a light polymerizable component, (ii) a photoinitiator, (iii) a heat polymerizable component, and (iv) a non-reactive diluent, which resin is useful for the production of three-dimensional objects by additive manufacturing. Methods of using the same are also provided.
US11845199B2 Installation and method for manufacturing cross-linkable polyethylene compounds
An installation for manufacturing cross-linkable polyethylene compounds which comprises a melting machine (101), a melt pump (102) and a filtration unit (103) to produce cross-linkable polyethylene compounds that may be further used for manufacturing insulating parts of medium, high and extra-high voltage power cables, and a method for manufacturing such cross-linkable polyethylene compounds.
US11845198B2 Processed slabs, and systems and methods related thereto
This document describes systems and processes for forming synthetic molded slabs, which may be suitable for use in living or working spaces (e.g., along a countertop, table, floor, or the like).
US11845193B2 Cross laser calibration device and calibration system using the same
A cross laser calibration device used to calibrate a tool center point is provided. The calibration device includes a coordinate orifice plate, a set of cross laser sensors and a rotational and translational movement mechanism. The coordinate orifice plate has an orifice center point. The set of cross laser sensors is arranged on the coordinate orifice plate to generate cross laser lines intersecting at the orifice center point. The set of cross laser sensors is driven by the second motor to rotate around the center point of the second motor, wherein the orifice center point has an off-axis setting relative to the center point of the second motor.
US11845186B2 Inverse kinematics solving method for redundant robot and redundant robot and computer readable storage medium using the same
An inverse kinematics solving method for redundant robot as well as a redundant robot using the same are provided. The method includes: obtaining an expression of a Jacobian matrix null space of a current configuration of each robotic arm of the redundant robot corresponding to a preset end pose of the robotic arm according to the preset end pose, and obtaining a relation between an angular velocity of the joints of the redundant robot in the Jacobian matrix null space of the current configuration based on the obtained expression; traversing the Jacobian matrix null space using the relation, and building an energy cost function of the redundant robot based on the relation; obtaining a target joint angle of each joint of the redundant robot based on the optimal inverse kinematics solution to transmit to the servo of the joint so as to control the joint.
US11845183B2 Deep reinforcement learning for robotic manipulation
Implementations utilize deep reinforcement learning to train a policy neural network that parameterizes a policy for determining a robotic action based on a current state. Some of those implementations collect experience data from multiple robots that operate simultaneously. Each robot generates instances of experience data during iterative performance of episodes that are each explorations of performing a task, and that are each guided based on the policy network and the current policy parameters for the policy network during the episode. The collected experience data is generated during the episodes and is used to train the policy network by iteratively updating policy parameters of the policy network based on a batch of collected experience data. Further, prior to performance of each of a plurality of episodes performed by the robots, the current updated policy parameters can be provided (or retrieved) for utilization in performance of the episode.
US11845179B2 Wafer jig, robot system, communication method, and robot teaching method
A wafer jig according to one or more embodiments may be used for a robot having a hand and a state detector. The hand can transport a wafer. The state detector detects a state of a member holding the wafer at the hand or a state of a negative pressure adsorbing the wafer at the hand. The wafer jig includes an information output part. The information output part outputs information to a hand side via the state detector by changing a detection result of the state detector.
US11845176B2 Finger mountable tool holder
The present invention relates to a device for mounting a tool on a hand of a user, the device comprises a receiving part for attachment of a tool and at least one mounting member for mounting the device on one or more fingers of the hand of the user, such as two neighbouring fingers, wherein the receiving part is fixed to the mounting member, and the receiving part comprises at least one clamp for clamping a tool to the device, wherein the clamp has a closed position (h2) and an open position (h1) and wherein the clamp is configured to be operable by one or more of the fingers of the same hand the device is mounted on. The invention further relates to a method of mounting a tool in the device, and to the use of the device.
US11845173B2 Anti bind-up control for power tools
Systems and methods for detecting and acting on bind-up conditions of a power tool. The power tool includes a housing, a motor, a battery pack, and a motion sensor configured to sense rotational motion of the housing. An electronic controller is connected to the motor, the battery pack, and the motion sensor. The electronic controller is configured to determine whether a battery fetting event is occurring and adjust a rotational motion threshold used to determine a bind-up event based on the battery fetting event. The electronic controller is further configured to receive, from the motion sensor, a first signal associated with a rotational motion of the housing, compare a value based on the signal to the rotational motion threshold, and initiate, in response to the value being greater than or equal to the rotational motion threshold, a protective operation.
US11845168B2 Reciprocating tool
A reciprocating tool includes a motor, a driving mechanism, a body housing, a movable part, and a vibration control mechanism. The driving mechanism includes a reciprocating member configured to reciprocate in a first direction. The movable part is connected to the body housing via a first elastic member and a second elastic member to be relatively movable in the first direction. The vibration control mechanism includes at least one weight configured to move in a direction opposite to the reciprocating member. The center of gravity of the at least one weight is offset from the driving axis in a second direction. In the second direction, the first elastic member is closer to the center of gravity than the second elastic member. A load of the first elastic member when the movable part is placed in a closer position is smaller than a load of the second elastic member.
US11845167B2 Fastener driving tool using a gas spring
A portable linear fastener driving tool is provided that drive staples, nails, or other linearly driven fasteners. The tool uses a gas spring principle, in which a cylinder filled with compressed gas is used to quickly force a piston through a driving stroke movement, while a driver also drives a fastener into a workpiece. The piston/driver is then moved back to its starting position by use of a rotary-to-linear lifter, and the piston again compresses the gas above the piston, thereby preparing the tool for another driving stroke. The driver has protrusions along its edges that contact the lifter, which lifts the driver during a return stroke. A pivotable latch is controlled to move into either an interfering position or a non-interfering position with respect to the driver protrusions, and acts as a safety device, by preventing the driver from making a full driving stroke at an improper time.
US11845163B2 Depth and angle sensor attachment for a power tool
A power tool including a sensor attachment, a housing, a motor, and a power tool controller. The power tool controller is operable or configured to control power provided to the motor. The sensor attachment is coupled to the power tool's housing and includes a first non-contact sensor and a sensor controller. The sensor controller receives signals from the first non-contact sensor related to distance to a work surface and determines a fastener depth based on the signals from the first non-contact sensor. If the fastener depth is greater than or equal to a desired fastener depth, the sensor controller generates and sends a control signal to the power tool controller. In response, the power tool controller turns off or cuts power to the motor.
US11845160B2 Cleaning device, cleaning method, and machine tool
A cleaning device arranged in a table which is driven. The cleaning device includes one or more cleaning through holes provided in the table and opened at positions facing a workpiece or a jig, a container unit provided in the table and including a storage space which receives cleaning fluid; a movable member that is arranged in the container unit, that defines the storage space, and that is supported movably in a direction intersecting a horizontal axis line; and a cleaning piping component connecting the storage space and the cleaning through holes.
US11845158B2 Thickness measuring apparatus
A thickness measuring apparatus that measures a thickness of a workpiece held by a chuck table. The thickness measuring apparatus includes plural image sensors that detect intensity of light spectrally split on each wavelength basis by plural diffraction gratings and generate a spectral interference waveform and a thickness output unit that outputs thickness information from the spectral interference waveform generated by the plural image sensors. The thickness output unit includes a reference waveform recording section in which spectral interference waveforms corresponding to plural thicknesses are recorded as reference waveforms and a thickness deciding section that compares plural spectral interference waveforms generated by the plural image sensors with the reference waveforms recorded in the reference waveform recording section and decides the thickness corresponding to each spectral interference waveform from the reference waveform that corresponds to the spectral interference waveform in the waveform shape.
US11845154B2 Processing apparatus
A processing apparatus includes a processing unit, a control unit, and a temperature detecting unit. The processing unit includes a cutting blade and a spindle assembly, the spindle assembly including a spindle having the cutting blade mounted on a distal end of the spindle and a spindle housing through which the spindle is inserted. A cooling fluid passage is formed in the spindle housing, the cooling fluid passage cooling the spindle assembly, and having one end connected to a cooling fluid supply source and having another end communicating with a cooling fluid outlet of the spindle housing. The temperature detecting unit detects the temperature of the spindle housing. The control unit determines whether a state of cooling of the spindle assembly is normal or abnormal on the basis of the temperature detected by the temperature detecting unit.
US11845153B2 Power tool including a battery pack isolation system
A power tool includes a housing, a motor positioned substantially within the housing, a drive mechanism supported by the housing and coupled to the motor, a battery pack electrically coupled to the motor, and an isolation system. The isolation system includes an interface member positioned substantially within the housing. The interface member receives a portion of the battery pack to electrically couple the battery pack to the motor. The isolation system also includes a plurality of isolators coupled between the housing and the interface member to isolate the battery pack from the housing during operation of the power tool.
US11845150B2 Methods and apparatus to provide welding-type power and preheating power
An example welding power supply includes: a power input configured to receive alternating current (AC) input power; and power conversion circuitry configured to: convert a first portion of the input power to welding power; output the welding power to a weld circuit; convert a second portion of the input power to preheating power; and output the preheating power to a preheater.
US11845149B2 Power supply and method for dual process welding
A method and apparatus for providing welding-type power that alternates between at least a hotter and a colder process is disclosed.
US11845148B2 Device and method for automatic narrow gap TIG welding
A welding device includes a welding torch having an electrode, an oscillation assembly having an oscillation shaft, and a connection member. The welding torch is affixed to the connection member at a first point and the oscillation shaft is affixed to the connection member at a second point. An extension of the axis of the oscillation shaft intersects with the axis of the welding torch at an intersection point. The distance from the intersection point to the tip of the electrode is less than a distance from the first point on the connection member to the tip of the electrode. During operation, the oscillation in the oscillation shaft is transferred through the connection member to the welding torch and causes pendulum type oscillations in the welding torch with the intersection point serving as the pivot point of the oscillation.
US11845146B2 Brazing wire, forming method of brazing wire and forming mold of brazing wire
A brazing wire includes a brazing tube having an inner cavity and a flux filled in the inner cavity. A trench is provided on an outer peripheral surface of the brazing tube, and the trench extends along an axis of the brazing tube or spirally extends around the axis. A forming mold of the brazing wire includes a mold body having a molding cavity therein. An inner wall of the molding cavity is provided with a protrusion. When the brazing wire passes through the forming mold, the protrusion is used to form the trench. The forming method of the brazing wire includes the following steps. The brazing tube passes through the forming mold, and the trench is formed on the outer peripheral surface of the brazing tube by the protrusion. The trench extends along the axis of the brazing tube or spirally extends around the axis.
US11845144B2 Additive manufacturing
A nanofluid laser entrainment additive manufacturing apparatus, system and method including a substrate, a dilute nanofluid of inert gas suspended nanoparticles on the substrate, a focused energy beam that irradiates the nanoparticles to selectively melt the nanoparticles, and a raster system that raster scans the focused energy beam across the inert gas suspended nanoparticles to create predetermined shapes by additive manufacturing.
US11845138B2 Systems and methods for case repair
A method for repairing a pocket of a case for a variable stator assembly may comprise: receiving, via a processor, a plurality of wear depths, each wear depth in the plurality of wear depths corresponding to a wear portion in a stator pocket in a plurality of stator pockets; determining, via the processor, a plurality of thicknesses of a coating to be deposited based on the plurality of wear depths, each thickness of the coating in the plurality of thicknesses corresponding to the wear portion for each stator pocket in the plurality of stator pockets; and commanding, via the processor, a coating spray torch to deposit the coating in the wear portion of each stator pocket in the plurality of stator pockets.
US11845137B2 Apparatuses and methods for induction heating
A heating apparatus for induction heating is disclosed. The heating apparatus may comprise a bearing ring, at least one bearing element disposed in the bearing ring, and a braze material adjacent to the at least one bearing element and the bearing ring. The heating apparatus may additionally comprise an inductor positioned radially adjacent to at least a portion of the bearing ring. A current source may be electrically coupled to the inductor. A bearing orienting member may also abut a surface of the at least one bearing element. The bearing orienting member may orient a surface of the at least one bearing element. A heating method is also disclosed.
US11845135B2 Miter gauge assembly
A miter gauge for guiding a work piece over a work platform has a base assembly that slides over the work platform and a fence that engages the work piece on the work platform. The fence is movable relative to the base assembly and includes a first locating member. A second locating member is operatively connected to the base assembly and selectively engages the first locating member of the fence. The second locating member moves between a locked position where the second locating member is engaged with the first locating member to inhibit movement of the fence and hold the fence at a preset position and an unlocked position where the second locating member disengages the first locating member so that the fence and base assembly are free to move relative to one another.
US11845134B2 Hole saw with hex sidewall holes
A hole saw including a plurality of sidewall openings is provided. The sidewall openings are shaped and grouped in patterns that improve debris ejection of the hole saw and that allow for easy access to the interior of the hole saw for manual debris removal by the user. The opening groups are space from each other by larger uninterrupted areas such that the hole saw has a high strength despite the number and size of openings provided in the saw sidewall.
US11845131B2 Method for manufacturing or for repairing a component of a rotary machine as well as a component manufactured or repaired using such a method
A component of a rotary machine extends to an axial direction and a radial direction vertical thereto, and has an inner channel, extending from a first end of a core of a center of the component and to a second end at a radial limiting surface of the component and which is at least partially closed. A blank includes the core of the component and is limited by an outer surface in the radial direction. The blank is subtractively processed in a first subtractive process step, such that an outer contour is elaborated in the area of the outer surface, which extends in the radial direction, and a part of the channel is manufactured, which radially extends in the blank to the first end. The channel is formed by a build-up process on the blank.
US11845130B2 Rotational additive manufacturing systems and methods
Systems and methods for rotational additive manufacturing are disclosed. An apparatus in accordance with an aspect of the present disclosure comprises a build floor, a depositor system configured to deposit a layer of powder onto the build floor, a motor system causing a rotational motion between the depositor system and the build floor, wherein the depositor system deposits the layer of powder during the rotational motion, a receptacle wall configured to contain the powder on the build floor, an energy beam source configured to apply an energy beam in an active area of the layer of powder to selectively fuse a portion of the powder in the active area to form a portion of a build piece and a gas flow system configured to provide a gas flow across the active area while the energy beam selectively fuses the portion of the layer of powder in the active area.
US11845126B2 Metal additive manufacturing extrusion mechanism for monitoring and improving mechanical properties in situ
The present disclosure relates to a metal additive manufacturing extrusion mechanism for monitoring and improving mechanical properties in situ, and belongs to the technical field of metal additive manufacturing. The mechanism comprises a wire conveying unit, a composite cavity unit, a high-temperature loading unit, a temperature detecting unit, a pressure loading unit, a pressure detecting unit and an in-situ monitoring unit. Multi-stage high-temperature loading is achieved through silicon nitride heater components distributed in the piston, the outer wall of the cavity and the nozzle, and meanwhile service temperature detection is achieved through thermocouple components. Multi-stage pressurization is achieved through continuous pressure loading of the wire conveying mechanism and high-frequency pressure loading of the piston mechanism and the four-rod mechanism, and then service pressure detection is achieved through strain gauge components on the top of the piston and the inner wall of the cavity.
US11845125B2 Method for manufacturing cast iron casting with fining graphite and suspension part
A method for manufacturing an austempered ductile cast iron and a product made from the austempered ductile cast iron manufactured by the method are disclosed. In the method for manufacturing an austempered ductile cast iron, spheroidizing agent and primary inoculant are added to a raw molten metal to create homogeneous spheroidal graphite creation in a deep part of a matrix and the raw molten metal to which the spheroidizing agent and the primary inoculant are added is injected into a mold to which secondary inoculant is locally applied, to micronize spheroidal graphite of a local structure coated with the secondary inoculant into fine graphite that is easy to machine, thereby enhancing workability as compared with a conventional austempered ductile cast iron.
US11845124B2 Roller casting method and system for producing a spiral structure
A roller casting method produces a spiral structure, in particular a spiral structure for use in electric machines. Molten metal is supplied between a first roller and a second roller miming opposite thereto, wherein the first roller has first teeth, and the second roller has second teeth, said first and/or second teeth having tooth flanks with cavities for receiving the supplied molten metal. The teeth are designed and aligned such that the cavity of at least one tooth is at least temporarily delimited by the surface of a tooth of the other roller when the rollers are rotating such that the supplied molten metal is molded between the teeth while cooling and is molded into a section of the spiral structure.
US11845123B2 Systems and processes for manufacturing nested components
A system for efficiently forming a plurality of shaped piece parts from a sheet of material comprises a sheet of piece part material from which the piece parts can be shaped and cut, a pattern for arranging the plurality of piece parts in a prearranged orientation, a series of joints connecting aligned ones of the piece parts within the pattern, a piece part cutting machine configured to separate a plurality of workpieces from the sheet of material according to the patterns and joints, a bending machine for simultaneously applying a first fold and a second fold, each across a respective set of aligned piece parts without breaking the series of joints, and a detacher for breaking the series of joints to groups and individual ones of joined piece parts.
US11845120B2 Bellow internal-external pressure crimping method and crimping- compressing device
Bellows are devices used to compensate linear, thermal, or angular movement/expansion. In oil and gas industry bellows are used in gas lift valves as a slidable seal between two gases. Gas lift valves are used in process of oil artificial lift from wells. Bellows having very thin walls are not well suited for pressures higher than approximately 200 PSI. To withstand much higher pressures bellows are being crimped, process that compresses the bellow to shorter length which increases bellow mechanical toughness. This patent application refers to bellow crimping method that uses initially balanced internal and external pressure to crimp bellow to desired length and maintain perfect bellow elements-convolution Ω geometry using custom designed crimping device.
US11845119B2 Workpiece drive and descaling device having a workpiece drive
A workpiece drive for rotating a circular workpiece in a descaling device has a carrier and at least three support roller modules. Each of the support roller modules has a bearing and a support roller for the circular workpiece. The support roller has a longitudinal axis, a lateral surface and a radius between the longitudinal axis and the lateral surface, and the radius decreases in a longitudinal direction along the longitudinal axis. The bearing supports the support roller rotatably around the longitudinal axis. Each of the support roller modules has a drive and the drive is designed to rotate the support roller around the longitudinal axis. The bearings are arranged on the carrier in such a way that the longitudinal axes have a point of intersection and lie in a plane perpendicular to the earth gravity field vector and such that the longitudinal directions are directed towards the point of intersection.
US11845116B2 Waste disposal system and waste receiver for receiving and disposing of pharmaceutical waste material
A waste receiver for receiving pharmaceutical waste material and adapted to be releasably secured to a fixed surface is disclosed. The waste receiver comprises a receiver body with a fluid absorber and a chemical composition disposed within the receiver body. The receiver body defines an opening for receiving the pharmaceutical waste material and comprises an inner surface defining a container volume in fluid communication with the opening, and an outer surface opposite the inner surface with the outer surface defining a lock passageway through the receiver body and a keyway comprising a portion of the lock passageway. The lock passageway is adapted to receive a locking assembly and the keyway is adapted to receive an engagement feature of the locking assembly to releasably secure the waste receiver to the locking assembly in a single orientation. The waste receiver also comprises a cover adapted to be coupled with the receiver body.
US11845114B2 Expandable device for defouling tubular members
A defouling device for mechanically disrupting fouling material for removal from a pipe or other a tubular member. The defouling device has inflatable portions capable of expanding to mechanically disrupt fouling material within a pipe. The defouling device may be attached to an inner luminal surface of the pipe or formed with the pipe. The defouling device expands circumferentially and radially to mechanically disrupt fouling material. The defouling device may also controllably expand longitudinally to mechanically disrupt fouling material and peristaltically pump fouling material through and out of the pipe.
US11845109B1 Roller assembly for a screening device
A roller assembly for a screening device includes a shaft extending along a width direction, a pair of discs disposed on the shaft, and a spacing assembly disposed on the shaft between the pair of discs. The spacing assembly includes an inner spacer disposed around the shaft and an outer spacer disposed around the inner spacer. The outer spacer has a body defining an inner receiving space and a support element disposed in the inner receiving space. The body abuts against the discs and is formed of an elastically compressible material. The support element limits compression of the body along the width direction.
US11845108B2 Methods for manufacturing ultrasound transducers and other components
The disclosed technology features methods for the manufacture of electrical components such as ultrasound transducers. In particular, the disclosed technology provides methods of creating an ultrasonic transducer by connecting one or more multi-layer printed circuits to an array of ultrasound transducer elements. In one embodiment, the printed circuits have traces in a single layer that are spaced by a distance that is greater than a pitch of the transducer elements to which the multi-layer printed circuit is to be connected. However the traces from all the layers in the multi-layer printed circuit are interleaved to have a pitch that is equal to the pitch of the transducer elements. The disclosed technology also features ultrasound transducers produced by the methods described herein.
US11845105B2 Soft plasma polymerization process for a mechanically durable superhydrophobic nanostructured coating
A method for depositing a coating on a substrate is disclosed. A first precursor comprising fluoro-acrylate monomers, fluoro-alkyl acrylate monomers, fluoro-methacrylate monomers, fluoro-alkyl methacrylate monomers, fluoro-silane monomers, or a combination or derivates thereof is provided. A second precursor comprising linear siloxanes, silane monomers, cyclosiloxanes, cyclosilane monomers, or a combination or derivates thereof is provided. The first and second precursors are co-injected in a treatment region. An atmospheric or reduced pressure plasma discharge is created in said treatment region. The substrate coating comprises alternated multi-stacked nanostructures and is formed by copolymerization of the first and second precursors.
US11845100B2 Electrospray device for fluidized bed apparatus, fluidized bed apparatus and method
The electrospray device comprises a sprayer comprising a sprayer body and nozzle, and a partition positioned vertically and coaxially with the sprayer. The sprayer body is provided with a swirl generator for generating a swirling air stream, and a power supply connected between the nozzle and the partition, to apply voltage to the nozzle and the partition. The electrospray device may be part of a fluidized bed apparatus comprising a product container, a lower plenum base, an air distribution plate resided therebetween. When the power supply applies voltage in opposite polarities to the nozzle and the partition, the fluidized bed apparatus is used for coating particles; and when the power supply applies voltage of the same, the fluidized bed apparatus is used for spray-drying a solution. The electrospray device uses an electromagnetic hydrodynamic method to improve the performance of the fluidized bed apparatus and optimize the process of product.
US11845099B2 Integrated electrospray emitter and methods for making same
An electrospray ionization emitter according to various aspects described herein can include an emitter body formed using fused silica. The emitter body can comprise a fluid conduit segment that includes a liquid connection end that has been coated with polyetheretherketone (PEEK) on at least one portion thereof. The liquid connection end can have a first outer diameter that is configured to be connected to a sample source to receive a sample liquid for ionization therefrom. The emitter body can further comprise an ionization discharge segment that is fluidly connected to the fluid conduit segment. The ionization discharge segment can have an ionization discharge end that is coated with a conductive material on at least one portion thereof and configured to have a second outer diameter that allows ionization of the liquid sample.
US11845096B2 Robot, system and method for electrostatic powder coating
An electrostatic powdering robot for a powder booth, the robot including a projector for performing electrostatic powder coating. In order to reduce the time required for powder removal from the booth and facilitate automation of powder removal, the robot further includes a robotic arm, which is articulated and which carries the projector for positioning the projector, as well as a blower, for blowing a powder removal fluid, preferably air, the robotic arm carrying the blower to position the blower inside the booth, so that the blower blows the powder removal fluid onto a surface to be de-powdered inside the electrostatic powdering booth and thereby removes the residual powder coating the surface to be de-powdered.
US11845093B2 Fluid product dispenser
Fluid product dispenser having a reservoir (R) with a threaded neck (R1) forming an external helical thread (R2), a closure element (T) having a threaded skirt (F1) forming an internal helical thread (F2), and a band (H) engaging around the threaded skirt (F1). The skirt has tabs (F11), each forming a segment (F21) of the internal helical thread (F2). The fastening member (F) has an angular indexing mechanism for positioning it with respect to the external helical thread (R2) with a determined angular orientation, and the segments (F21) of the internal helical thread (F2) of the threaded skirt (F1) come into corresponding threaded contact with the external helical thread (R2) of the neck (R1) in the final assembly position.
US11845092B2 Vehicle washing device
A vehicle washing device includes: a cylinder including a cylinder tube to which a washing fluid is supplied; a piston including a piston tube that is movably inserted into the cylinder tube and opens at both ends; and a spray nozzle that is mounted at a leading end, in an extension direction, of the piston tube protruding from the cylinder tube. The spray nozzle is configured to spray the washing fluid, supplied through the inside of the piston tube, toward an object-to-be-washed. The outer circumference of the spray nozzle is fitted on the inner circumference of the piston tube.
US11845091B2 Multi-mode fluid nozzles
A multi-mode fluid nozzle includes a generally-cylindrical mixing chamber with a stream mode fluid inlet connected to one side of the chamber, a fluid outlet connected to the opposite side of the chamber and a mist mode fluid inlet connected to the periphery of the chamber. The discharge pattern of the multi-mode fluid nozzle is dependent upon the inlets from which fluid enters the mixing chamber such that when the fluid enters the mixing chamber through the stream mode fluid inlet, the fluid exits the fluid outlet in a stream flow discharge pattern, when the fluid enters the mixing chamber through the mist mode fluid inlet, the fluid exits the fluid outlet in a mist flow discharge pattern and when the fluid enters the mixing chamber through the stream mode and the mist mode fluid inlet, the fluid exits the fluid outlet in a droplet flow discharge pattern.
US11845087B2 Hydroseeders having integrated bale grinders and methods
In one embodiment, a hydroseeder has an integrated bale grinder. The hydroseeder includes a tank, an agitator, a plurality of grinding flights, and a basket. The tank includes an opening and is configured to hold a material slurry. The agitator is positioned below the opening and is configured to agitate the material slurry. The plurality of grinding flights extends from the agitator and is configured to grind a material bale as it is introduced into the tank. The basket extends from the opening of the tank and is configured to direct the material bale toward the plurality of grinding flights.
US11845085B2 Feed system for grinding bodies in vertical mills
A feed system for feeding grinding bodies to a vertical mill includes a pumping unit for sucking a propulsion liquid from a source and for supplying the liquid under pressure into a discharge tube. The system includes an intake connection having an inlet for grinding bodies, an inlet for propulsion liquid, connected to the discharge tube, and an outlet for grinding bodies and propulsion liquid. A principal tube is connected to the outlet of the intake connection for receiving the propulsion liquid and grinding bodies from the tubular intake connection. A static screen is arranged in the feed of the vertical mill for separating grinding bodies from propulsion liquid, the static screen having an inlet for propulsion liquid and grinding bodies, connected to the principal tube, an outlet for grinding bodies to be fed to the vertical mill, and an outlet for propulsion liquid separated from the grinding bodies.
US11845083B2 Container
A container includes a container main body including a housing part and an opening, and a lid configured to close the opening and including an insertion part configured to be inserted to the opening. The outer peripheral surface of the insertion part includes first and second protrusions and first and second recesses. The inner peripheral surface of the opening includes third and fourth protrusions and third and fourth recesses. When the insertion part is temporarily inserted to the opening, the third protrusion presses the first recess in a state where the first protrusion is housed in the third recess. When the insertion part is fully inserted to the opening, the third protrusion presses the second recess and the fourth protrusion presses the first recess in a state where the first protrusion is housed in the fourth recess and the second protrusion is housed in the third recess.
US11845080B2 Temperature control system for microfluidic device
A heating system for an EWOD device using a single, spatially-structured temperature control element, used to create a zone with a specific temperature profile. The heating system uses multiple contact regions between the temperature control element and the device. One or more contact regions are separated from the temperature control element by one or more thermally resistive layers that restrict heat flow from the temperature control element to the device, and further restrict lateral flow of heat between adjacent contact regions. The heating system can use materials with different thermal resistance to alter the heat flow to different regions. The spatial location of the contact regions is also used to determine the temperature profile within the device. The device has an optional temperature control element which offsets the low temperature point from the inlet temperature. This invention includes methods to process multiple droplets within the multiple temperature zones.
US11845078B2 Systems and methods for detection and quantification of analytes
Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
US11845076B2 System for ejecting tips of sampling pipettes with improved ergonomics
A system for ejecting tips of sampling pipettes, the system comprising: —a button for ejecting a tip which is intended to be moved in translation by an operator's thumb; —a tip ejection device; and —return spring for returning the tip ejection device to a raised position. According to the invention, the system also comprises a lever for controlling the ejection device, the control lever comprising: —a first end which is intended to be fitted onto a part of the pipette; —a second end cooperating with the eject button so as to be acted upon by the latter; and —an intermediate portion for actuating the ejection device.
US11845075B2 Rotary feeder with cleaning nozzles
A rotary feeder having a stationary, cylindrical housing having disposed therein a number of injection nozzles, and within which rotate a plurality of vanes about a central axis, wherein pairs of adjacent vanes of the plurality of vanes define wedge volumes, wherein the housing extends a width along the central axis, wherein each of the vanes has a length along the central axis, and wherein the injection nozzles are positioned across the width of the housing, such that a spray pattern of a gas injected via the number of injection nozzles spans substantially the entire length of the vanes.
US11845071B2 Intermetallic catalyst and method for preparing the same
Disclosed is a method of preparing an intermetallic catalyst that includes irradiating ultrasonic waves to a precursor admixture including a noble metal precursor, a transition metal precursor, and a carrier to form core-shell particles including a transition metal oxide coating layer; the annealing the core-shell particles to form intermetallic particles including a transition metal oxide coating layer; and the removing the transition metal oxide coating layer from the intermetallic particles.
US11845066B2 Molecular sieve SSZ-123, its synthesis and use
An aluminum-rich molecular sieve material of MFS framework type, designated SSZ-123, is provided. SSZ-123 can be synthesized using 1-ethyl-1-[5-(triethylammonio)pentyl]piperidinium cations as a structure directing agent. SSZ-123 may be used in organic compound conversion and/or sorptive processes.
US11845065B2 Palladium fixing and low fresh oxygen storage capacity using tannic acid as a complexing and reducing agent
A method of manufacturing a catalyst article, the method comprising: providing a complex of a polyphenol and a PGM, the polyphenol comprising an ester functional group, the PGM comprising palladium; providing a support material; applying the complex to the support material to form a loaded support material; disposing the loaded support material on a substrate; and heating the loaded support material to form nanoparticles of the PGM on the support material.
US11845062B2 Method for producing an adsorption agent for treating compressed gas and an adsorption device provided with such an adsorption agent
A method for manufacturing an adsorption agent for treating compressed gas, which includes the steps of providing a monolithic supporting structure; producing a coating suspension that includes an adsorbent; applying the coating suspension on the supporting structure to form a coating; applying a thermal treatment to the coated supporting structure in order to sinter the coating.
US11845061B1 Complex structures obtained from dissolving-droplet nanoparticle assembly
Some variations provide an interspersed assembly of nanoparticles, the assembly comprising a first phase containing first nanoparticles and a second phase containing second nanoparticles, wherein the second phase is interspersed with the first phase, and wherein the first nanoparticles are compositionally different than the second nanoparticles. The interspersed assembly may be a semi-ordered assembly comprising discrete first-phase particles surrounded by a continuous second phase. Other variations provide a core-shell assembly of nanoparticles, the assembly comprising a first phase containing first nanoparticles and a second phase containing compositionally distinct second nanoparticles, wherein the second phase forms a shell surrounding a core of the first phase. The disclosed assemblies may have a volume from 1 μm3 to 1 mm3, a packing fraction from 20% to 100%, and an average relative surface roughness less than 5%, for example. Methods of making these assemblies are described, and many experimental examples are included.
US11845058B2 Cooperative chemical adsorption of acid gases in functionalized metal-organic frameworks
A system and method for acid gas separations using porous frameworks of metal atoms coordinatively bound to polytopic linkers that are functionalized with basic nitrogen ligands that expose nitrogen atoms to the pore volumes forming adsorption sites. Adjacent basic nitrogen ligands on the metal-organic framework can form an ammonium from one ligand and a carbamate from the other. The formation of one ammonium carbamate pair influences the formation of ammonium carbamate on adjacent adsorption sites. Adsorption of acid gas at the adsorption sites form covalently linked aggregates of more than one ammonium carbamate ion pair. The acid gas adsorption isotherm can be tuned to match the step position with the partial pressure of acid gas in the gas mixture stream through manipulation of the metal-ligand bond strength by selection of the ligand, metal and polytopic linker materials.
US11845054B2 Methods and devices for nucleic acids synthesis
Methods and apparatus relate to the synthesis of polynucleotides having a predefined sequence on a support. Assembly methods include primer extension to generate overlapping construction oligonucleotides and assembly of the polynucleotides of interest onto an anchor support-bound oligonucleotides. Methods and apparatus for selection of polynucleotides having the predefined sequence and/or length are disclosed.
US11845047B2 Systems and methods for improved mixing
Systems and methods for improved mixing, including baffle systems, reactor systems, and methods of using the same are provided herein. These baffle systems include a ring having an exterior surface defining an outer diameter and an outer circumference, an interior surface defining an inner diameter and an inner circumference, a top surface, a bottom surface, and an axis; and one or more substantially vertical baffles extending from the interior surface of the ring toward the axis.
US11845046B2 Mixing system and method of using the same
A mixing system is configured to mix and discharge a paste. The mixing system includes a base-medium subsystem that provides a base fluid-medium. The mixing system further includes an additive-medium subsystem that provides one or more additive fluid-mediums. The mixing system further includes a density-reducing medium subsystem that provides a density-reducing medium.
US11845043B2 Large bubble mixer and method of using same in a wastewater treatment system
A mixer configured for releasing large bubbles into wastewater is provided. The mixer can include a central draft tube, an upwardly-extending member surrounding the draft tube, and an accumulator surrounding both the upwardly-extending member and the draft tube. A lower end of the draft tube sidewall may be sealed and not include any openings beneath the lower end of the upwardly-extending member, so as to prevent liquid pumpage through the draft tube. A method for treating wastewater in a system that includes at least one large bubble mixer and at least one fine bubble diffuser is also provided. The large bubble mixer and fine bubble diffuser may be supplied gas independently from one another. The method can include multiple modes of operation wherein gas is either supplied to the mixer, to the diffuser, to neither the mixer or the diffuser, or to both the mixer or the diffuser.
US11845042B1 Automated tank mixing
A method is taught for maintaining a fluid within a tank. In this method an upper data acquisition device is operated which is capable of obtaining at least one characteristic of the fluid in a tank adjacent to the upper data acquisition device. A lower data acquisition device is also operated which is situated below the upper data acquisition device, capable of obtaining at least one characteristic of the fluid in the tank adjacent to the lower data acquisition device. A data analyzer is then utilized which is capable transmitting a data packet to the intermittent mixer. The method then automatically turns on the intermittent mixer from the data received from the data packet. Afterwards, the method automatically turns off the intermittent mixer from the data received from the data packet resulting in the at least one characteristic from the upper data acquisition device is within specifications of the at least one characteristic from the lower data acquisition device. In this method the intermittent mixer is capable of altering the fluid within the tank so that the at least one characteristic is consistent throughout the tank.
US11845041B2 Electrically conductive membrane assembly and related systems and methods
A membrane assembly for separating a feed liquid into a permeate and a retentate includes a semipermeable membrane and conductive members for applying a voltage effective for charging a semipermeable surface of the membrane, thereby reducing or preventing fouling or scaling of the membrane. The conductive members may be positioned adjacent to the semipermeable membrane, and may be configured as feed spacers or permeate spacers. Alternatively or additionally, the membrane may be electrically conductive. Power from an external source may be supplied to one or more of the conductive members, or also the membrane if conductive, which may be done wirelessly. One or more membrane assemblies may be provided in a container. One or more membrane assemblies may be provided in a stacked configuration, or wrapped around a tube in a spiral configuration.
US11845040B2 Flue gas treatment method and installation
Method and installation for treating a CO2- and H2O-containing flue gas generated by an industrial process unit before CCUS, whereby the flue gas evacuated from the unit is subjected to cooling to a temperature T2 between 100 and 600° C., whereby the cooled flue gas is pretreated in one or more particle removal and/or gas cleaning and/or drying stages and the temperature of the cooled flue gas is further reduced to a temperature T3
US11845039B2 Water extracting device
A device for extracting water vapour from a fluid stream includes a carrier structure, a substrate of fibrous material provided on the carrier structure, the fibrous material including a plurality of individual fibres, a quantity of an LCST polymer coating the individual fibres; and a heating provision arranged to selectively heat the LCST polymer to above its lower critical temperature whereby water absorbed by the fibres can be subsequently released on heating. By providing the LCST polymer as a coating onto the fibres, an increased surface area may be achieved.
US11845034B2 Vehicle provided, at the intake, with an heatable air filter provided and corresponding heatable air filter
A vehicle provided with an engine, at least one air intake through which the engine takes in the external air needed to operate, and an air filter arranged downstream of the air intake. The air filter presents: at least one filtering material panel having a corrugated shape having a plurality of crests disposed towards an outer environment and a plurality of valleys arranged towards an internal environment; an outer reinforcement mesh; an inner reinforcement mesh; and a heating device which is designed to heat the filtering material panel. The heating device presents: a plurality of electrical conductors, which are completely independent and separated from the outer reinforcement mesh, rest on the outer surface of the filtering material panel, and are arranged only and exclusively at the crests; and a supply device designed to cause an electric current to flow through the electric conductors so as to generate heat, due to the Joule effect.
US11845030B2 Method for collecting dust from single crystal growth system and dust collecting system thereof
A dust collecting system for single crystal growth system includes an air compressor, a dust collecting device, a first inert gas source, a rotary pump and a scrubber. The air compressor is fluidly connected to an exit pipe of the single crystal growth system. The exit pipe is used to exhaust unstable dust from the single crystal growth system. The dust collecting device is fluidly connecting to the exit pipe to collect the dust oxide. The first inert gas source is fluidly connected to the exit pipe to blow a first inert gas into the exit pipe to compel the dust oxide toward the dust collecting device. The rotary pump is fluidly connected to the dust collecting device. The scrubber is fluidly connected to the rotary pump. The rotary pump transports the residual dust oxide toward the scrubber. The present disclosure further provides a method for collecting dust.
US11845024B2 Modular filtration device and system
A modular filtration device is composed of a modular docking plate having at least one quick disconnect plumbing coupling; at least one electrical connector; and at least one alignment feature for aligning and receiving a modular filter; and a modular filter composed of a docking face having: at least one quick disconnect plumbing coupling; at least one electrical connector; and at least one alignment feature that mates with an alignment feature of the modular docking plate to provide proper alignment of the filter with the docking plate, engagement of the quick disconnect plumbing couplings, engagement of the electrical connectors, and engagement of the locking mechanism. The modular filtration device comprises a locking mechanism to hold the filter in place during operation. A modular filtration system is composed of a plurality of the filtration devices.
US11845022B2 Method and apparatus for dehydration and decarboxylation of cannabis
In a system for performing a multi-step process for selectively purifying various pharmacologically-relevant components of a source plant such as cannabis, an initial step of the process provides a low-temperature, robust process for dehydrating and decarboxylating the starting product—fresh raw cannabis—by means of a vacuum-assisted microwave distillation process. An important by-product of the dehydration/decarboxylation is a terpene-rich distillate. By doing the terpene capture under vacuum, distillation temperature may be kept low. The low distillation temperature maximizes yields of thermally-sensitive components such as terpenes and cannabinoids.
US11845020B2 System and method for a filter system
A variable pore size filter media including an upper plate, a retainer, and a support profile disposed between the upper plate and the retainer. The variable pore size filter media also includes a plurality of wire rings disposed on the support profile and longitudinally distributed within a region between the upper plate and the retainer, the plurality of wire rings being distributed in a non-contiguous manner to form a plurality of spaces therebetween. The variable pore size filter media further includes a plurality of pores defined by the plurality of spaces between the plurality of wire rings and a pore size adjustment mechanism configured to vary a respective distance between each of the plurality of wire rings to increase or decrease a respective size of each of the plurality of pores by increasing or decreasing a size of each of the plurality of spaces.
US11845019B2 Large format melt-blown depth filter cartridge
A tubular depth filter element has three or more concentric zones. Each zone is made of an essentially continuous melt blown filament. The filament of an outer zone preferably has a larger diameter than the filaments of other zones. The outer zone overlaps with at least 85%, and preferably all, of another zone. Optionally, one or more additional filaments may traverse through all of zones. The depth filter element is made by spraying filaments onto a rotating mandrel to form a filament mass in contact with a conical press roller. The filaments are sprayed from three or more nozzles which are spaced apart along the length of the mandrel. One of the filaments is formed in a spray pattern that is angled towards an adjacent spray pattern so as to overlap with at least 50 or 85%, and preferably all, of the adjacent spray pattern.
US11845014B2 Interactive modular construction element and a modular construction system with interactive modular construction elements
An interactive modular construction element (100) for a modular construction system (200), the interactive modular construction element (100) comprising a sensor (601) being responsive to a predetermined sensor input and adapted to output a sensor signal (610) corresponding to or representing the predetermined sensor input, a function element (602) adapted to perform at least one controllable function in response to a control signal (611), and a control circuit (603) connected to the sensor (601) to receive the sensor signal (610) and connected to the function element (602) to provide the control signal (611), wherein the control circuit (603) is adapted to provide the control signal (611) in response to the sensor signal (610) thereby controlling the function element (602) in response to the sensor signal (610), wherein the interactive modular construction element (100) comprises an input part (101) and an output part (102), where the input part (101) and the output part (102) are different from each other.
US11845012B2 Selection of video widgets based on computer simulation metadata
Computer game metadata is used to select a video widget provided in a video template. The widget can be operable to present metadata in the video template, change an association between features of the video template and metadata generated during play of a computer game, search for clips similar to a video clip presented by the video template, vary a length of a video clip presented by the video template, or vary an intensity of action used to select a video clip presented by the video template.
US11845010B2 Gaming content recommendation based on gaming performance
Systems and methods for recommending video game content based on video game performance are disclosed. A level is identified from among a sequence of playable levels of a currently active video game. A video game performance metric for the identified level is determined. Based on the determined video game performance metric, a video of a performance of the identified level of the video game is selected for recommendation from among a plurality of videos stored in a database in association with corresponding video game performance metrics. An option, which is selectable to cause playback of the selected video, is transmitted for display via a computing device.
US11845004B2 Game execution environments
Systems and methods are provided for cloud gaming. One system includes a plurality of computing resources in one or more data centers. The plurality of computing resources is configured to execute instances of games for client devices that are remote from the one or more data centers. Each instance for an executable game is associated with a processor, a graphics processing unit (GPU), and memory for storing video frames generated for the executable game. The video frames are compressed for video game streaming to one or more client devices. The executable game provides video and audio and receives input from said one or more client devices. The input is provided to control interactivity of the executable game during said video game streaming. The cloud gaming system uses said received input from said one or more client devices to drive instances of the executable game when executed by the computing resources of the one or more data centers.
US11845003B2 Game device and golf game control method
Provided is a golf game that is readily intuitively playable by a user. An input reception section receives an operation input indicating a motion of an input device gripped by the hands of the user. A control section controls a motion of a player character in a game space in accordance with the operation input. An image generation section generates a game image. When a golf club held by the player character comes into contact with the ground in the game space, the control section drives a stimulus generation section disposed in the input device to stimulate the user's hands gripping the input device.
US11845002B2 Interactive game system and method of operation for same
An interactive game system for implementing an interactive game in a room. The interactive game system comprises: a motion sensing module, a control unit, a projection module and a lighting module. The motion sensing module senses movement of a real-world element and surface interaction data representative of a contact between the real-world element and an interactive surface is generated therefrom. The control unit generates graphic instructions and lighting instructions based on the surface interaction data, in accordance with an implementation of a gameplay of the interactive game. The projection module receives the graphic instructions from the control unit and projects graphics on the interactive surface in accordance therewith. The lighting module receives the lighting instructions from the control unit and performs illumination of a section of the room distinct from the interactive surface in accordance therewith.
US11844999B2 Billiard table with dining table conversion-top
An embodiment of an improved design of a billiard table set with a dining table conversion-top, containing a billiard table with movably attached dining top segments, designed to eliminate inconvenient removal and storage of removable tabletop segments. The billiard dining table set furthermore contains benches featuring a custom height adopted to enable comfortable seating and foldable legs that enable storage of the benches under the dining table. Other embodiments are described and illustrated.
US11844996B2 Lift, drop, swing, and attenuation apparatus and method
A tower may support a horizontal track and a vertical climbing wall therebelow. A trolley, movable along the track, may be selectively driven toward and away from the tower by belay lines, line and capstan, positive drive, or some combination. Belay lines reeved over pulleys on the trolley may be taken up and paid out independently from the trolley, while fixed or moving. A rider may climb, be lifted, or both to near the intersection of the tower and track, from there to fall or jump into a controllable trajectory such as swinging or simulating a parachute landing. Swinging may be rapidly attenuated almost entirely by “bumps,” lifting a rider to remove momentum and kinetic energy as a rider moves toward a pivot point overhead. Control may be simplified based on sensing and using timing past bottom dead center (BDC).
US11844992B2 Tennis self-training system
The tennis ball supply device according to an embodiment of the present invention includes a communication circuit configured to communicate with an external device; a launcher configured to launch a ball; a body unit configured to move the launcher; and a controller configured to: control the body unit to move to a first position, identify whether the body unit is disposed on the first position based on a signal received from the communication circuit, based on identifying that the body unit is disposed on the first position, control the launcher to launch the ball, control the body unit to move to a second position after the launcher has stopped launching the ball, and identify whether the body unit is disposed on the second position based on the signal received from the communication circuit.
US11844986B2 Sporting goods including microlattice structures
A sporting good implement, such as a hockey stick or ball bat, includes a main body. The main body may be formed from multiple layers of a structural material, such as a fiber-reinforced composite material. One or more microlattice structures may be positioned between layers of the structural material. One or more microlattice structures may additionally or alternatively be used to form the core of a sporting good implement, such as a hockey-stick blade. The microlattice structures improve the performance, strength, or feel of the sporting good implement.
US11844983B1 Golf ball core with tailored hardness gradient
Compositions including a hardness agent and golf ball cores made from such compositions having a tailored hardness gradient are disclosed. The type and concentration of the components in the composition, including the hardness agent, affects the hardness, hardness gradient, and compression of cores made from the composition and, thus, can be used to produce a golf ball having desirable performance characteristics.
US11844981B2 Golf ball placement system and a method of operating the same
A golf system. The golf system includes a computing device associated with a user at a playing surface having at least one landmark object. The computing device includes a processor and a memory coupled to the processor. The memory may store processor-executable instructions that, when executed, configure the processor to: obtain topography data associated with a virtual golf hole for a virtual golf ball; determine a target destination location for the virtual golf ball on the playing surface based on the topography data and an anticipated virtual golf ball trajectory; and generating signals for communicating the target destination location and a ball placement location on the playing surface.
US11844976B2 Fitness apparatus and method
A vertically oriented fitness apparatus utilizes a combination of upper and lower assemblies resistant to vertical motion when the user pushes and pulls against crossbar members of the assemblies vertically. In alternate embodiments of the apparatus, resistance is provided by a dual action dashpot such as an adjustable bidirectional hydraulic damping cylinder which may be used in combination with spring resistance elements. The user is thus able to perform strength training and fitness conditioning exercises for both upper and lower extremities, and their core simultaneously while using the apparatus.
US11844975B2 Fire suppressant
A fire suppressant including technical urea 10-30% (by weight), ammonium sulphate 20-50%, and sodium bentonite 12-26%. The fire suppressant further includes polypropylene glycol (polyglycol), alkyl sulfonic acid, castor oil, guar gum, and/or triethanolamine dodecylbenzene sulfonate. The fire suppressant does not pose any risk to plant or animal life since the product is completely benign and is classified as non-toxic. It does not cause any damage to aquifers or groundwater, and it biodegrades in 30 to 60 days.
US11844972B2 Dry sprinkler assemblies
A dry sprinkler assembly capable of providing fire suppression protection, including early suppression fast response protection and storage protection of a commodity having a nominal storage height of at least 20 feet beneath a ceiling of with a maximum nominal 40 foot ceiling height. The dry sprinkler assembly includes an internal passageway and an outlet defining a nominal K-factor of at least 16.8 GPM/PSI1′2. Embodiments of the sprinkler assembly include a deflector having a plurality of tines radially disposed about a central portion to define slots therebetween. Embodiments of the deflector define a non-planar deflecting member and a member with a non-circular perimeter. Installation of the sprinkler assembly provides for a insulation sealing assembly having a insulation ring, planar insert member and a surrounding housing.
US11844971B2 Controlled system and methods for storage fire protection
Fire protection systems and methods for ceiling-only high-piled storage protection. The systems include a plurality of fluid distribution devices disposed beneath a ceiling and above a high-piled storage commodity having a nominal storage height ranging from a nominal 20 ft. to a maximum nominal storage height of 55 ft. and means for quenching a fire in the storage commodity. The stored commodity to be protected may include exposed expanded plastics. The fluid distribution devices include a frame body having an inlet, an outlet, a sealing assembly, and an electronically operated releasing mechanism supporting the sealing assembly in the outlet.
US11844970B2 System and method for guiding a user operating a fire extinguisher
A system comprising a fire extinguisher, one or more indicator devices disposed on the fire extinguisher adapted to actuate in a series representing a series of operations to be performed by a user for extinguishing a fire with the fire extinguisher, and a controller for controlling the actuation series of the one or more indicator devices.
US11844969B2 Systems and methods for improving fire safety in agricultural machinery
Systems for improving fire safety in agricultural machinery are configured for detecting, at least partially controlling, and/or suppressing adverse fire-related conditions. The adverse fire-related conditions can include sparks, embers, and/or flames in the agricultural machinery.
US11844967B2 Respirator
A tool, such as a respirator, including a body, an opening defined by the body, a door coupled to the body, and a filter positioned between the body and the filter. The door actuates between open and closed positions. The filter can be removed and replaced when the door is in the open position.
US11844963B2 Systems and methods for synthetic photon radiation therapy
Example methods and systems for photon energy synthesis and introducing energy modulation into radiation treatment planning process and delivery process are provided. Example methods comprise obtaining, via a linear accelerator, a first photon energy beam dosimetric data, a second photon energy beam dosimetric data, and an intermediate photon energy beam dosimetric data, and fitting the first photon energy beam dosimetric data and the second photon energy beam dosimetric data according to a preset fitting coefficient. A synthesized photon beam is then generated from dosimetric data from the fitted first photon energy beam dosimetric data and the fitted second photon energy beam dosimetric data. Further, continuously variable photon energies can be derived, where two or more existing photon energy beams are combined linearly and applied to both forward and inverse radiation planning modules for a radiation treatment plan.
US11844960B2 Method for evaluating radiotherapy planning
The present invention relates to a method for evaluating radiotherapy planning. The present invention provides a method for evaluating radiotherapy planning, the method comprising the steps of: (a) acquiring a dose distribution of generated radiotherapy planning for the target volume according to the prescribed dose; (b) calculating dose gradient index (DGI) of 3-dimensional isodose levels of the acquired dose distribution, by using distances between the isodose levels; and (c) generating a differential dose gradient curve (dDGC) by plotting the calculated dose gradient index (DGI) as a function of the dose over the range of dose distributions.
US11844958B2 Gland treatment devices and methods for treating dry eye disease
Systems, devices and methods that facilitate safe heating of eyelids to treat dry eye are disclosed. According to one embodiment, an apparatus for optical heating of an eyelid of a patient includes: a housing configured to be grasped by a human hand; at least one light emitter coupled to the housing and configured to emit beams of infrared light; a waveguide component coupled to the at least one light emitter and configured to direct the beams of light toward the eyelid; and a scleral cover configured to couple to the housing, the scleral cover comprising: a curved protective portion configured to reflect infrared light emanating from the at least one light emitter.
US11844955B2 Electrostatic drug delivery
A method for targeted drug delivery. The method includes preparing a drug composition with a surface electric charge, injecting the drug composition into a cancer patient's body, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of the surface electric charge of the drug composition to the electrically conductive element.
US11844951B2 Earpiece assembly to interact with implantable neural stimulators
An ear-piece assembly includes (i) an antenna portion enclosing a transmitting antenna configured to send one or more input signals containing electrical energy to a passive implantable neural stimulator device such that the passive implantable neural stimulator generates one or more stimulation pulses suitable for stimulating a neural structure in the craniofacial region solely using the electrical energy in the input signals; and (ii) an enclosure coupled to the antenna portion, wherein enclosure is sized and shaped to be mounted on a helix portion of an ear such that, when worn by a patient, weight from the enclosure is distributed over the helix portion of the ear for the enclosure to rest thereon, wherein the enclosure comprises (i) a controller module configured to provide the one or more input signals to the transmitting antenna, and (ii) a battery adapted to provide energy to the ear-piece assembly.
US11844949B2 Cardiac defibrillation
A cardiac defibrillation system that includes a pulse generator to generate therapeutic electrical pulses and at least one lead inserted through an intercostal space in the region of a cardiac notch of the left lung of a patient, the lead having a distal end configured to transmit the therapeutic electrical pulses generated by the pulse generator to defibrillate the heart of the patient.
US11844947B2 Spinal cord stimulation occurring using monophasic pulses of alternating polarities and passive charge recovery
New waveforms for use in an implantable pulse generator or external trial stimulator are disclosed which mimic actively-driven biphasic pulses, and which are particularly useful for issuing low frequencies pulses. The waveforms comprise at each electrode interleaved first and second pulses. Each first pulse comprises a first monophasic pulse and a first passive charge recovery period. Each second pulse comprises a second monophasic pulse with a polarity opposite the first monophasic pulse and a second passive charge recovery period. Preferably, the amplitudes and pulse widths of the first and second monophasic pulses are equal, or at least charge balanced at each electrode. The first and second monophasic pulses mimic the functionality of a symmetric biphasic pulse, with the first monophasic pulse mimicking the functionality of the biphasic pulse's first phase, and the with the second monophasic pulse mimicking the functionality of the biphasic pulse's second phase.
US11844945B1 Movement disorder therapy system, devices and methods of remotely tuning
The present invention relates to methods for remotely tuning treatment parameters in movement disorder therapy systems where the subject and clinician are located remotely from each other. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning remotely, allowing for home monitoring of subjects.
US11844944B2 System and apparatus for automated quantitative assessment, optimization and logging of the effects of a therapy
A method for assessment, optimization and logging of the effects of a therapy for a medical condition, including (a) receiving into a signal processor input signals indicative of the subject's brain activity; (b) characterizing the spatio-temporal behavior of the brain activity using the signals; (c) delivering a therapy to a target tissue of the subject; (d) characterizing the spatio-temporal effect of the therapy on the brain activity; (e) in response to the characterizing, optimizing at least one parameter of the therapy if the brain activity has not been satisfactorily modified and/or has been adversely modified by the therapy; (f) characterizing the spatio-temporal effect of the at least one optimized parameter; and (g) logging to memory the at least one optimized parameter. A computer readable program storage unit encoded with instructions that, when executed by a computer, performs the method.
US11844943B2 Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
The disclosure describes devices and methods for providing transdermal electrical stimulation therapy to a subject including positioning a stimulator electrode over a glabrous skin surface overlying a palm of the subject and delivering electrical stimulation via a pulse generator transdermally through the glabrous skin surface and to a target nerve or tissue within the hand to stimulate the target nerve or tissue within the hand so that pain felt by the subject is mitigated. The pulses generated during the electrical stimulation therapy may include pulses of two different magnitudes.
US11844942B2 Method of inhibiting proliferation of tumor cell using triboelectric energy generator using ultrasonic wave
A triboelectric energy generator includes a substrate, a first triboelectric member disposed on the substrate in a first partial region of a top face of the substrate, a second triboelectric member disposed on the substrate in a second partial region of the top of the substrate, a third triboelectric member disposed above and spaced from the first triboelectric member and the second triboelectric member. The first triboelectric member, the second triboelectric member, and the third triboelectric member are made of different materials. When an ultrasonic wave is applied to a top face of the third triboelectric member, the third triboelectric member is constructed to alternately contact and non-contact both the first triboelectric member and the second triboelectric member, thereby to generate triboelectricity.
US11844935B2 Cover for liquid delivery system with integrated plunger position sensing using focused optical beam and linear potentiometer
A sliding cover for a liquid delivery device, such as a cap (100) for a pen injector (200), incorporates a set of sensors including an optical sensor (110) with an output which changes during uncapping or capping motions on passing of a plunger (220) of the pen injector. This output is used together with a position sensor (120) to determine the position of the plunger along a cylinder (210) of the liquid delivery device. By monitoring changes in the plunger position, the quantity of dosages delivered by the liquid delivery device can be determined, displayed, stored and/or transmitted to an external device for further data processing or storage. Preferred implementations of the invention employ optical sensors with a converging beam (115), and/or position sensors employing linear potentiometer strips (132).
US11844934B2 Device and method for intraocular fluid injection
Devices and methods for intraocular fluid injection are disclosed. A device can include a surgical instrument for an ophthalmic procedure. The surgical instrument can include a handle. A fluid compartment can be coupled to the handle and configured to hold a substance. A tool can be coupled to the distal end of the handle and have a lumen configured to convey the substance into an intraocular site of a patient. A piston can be in the handle and configured to reciprocate along the longitudinal axis of the handle to draw the substance from the fluid compartment and eject the substance through the lumen of the tool. A push button can be on the lateral side of the housing and configured to engage the piston via a sloped surface to actuate a forward stroke of the piston towards the distal end of the handle.
US11844924B2 Method for reliable intermodule connection in an infusion system
A patient care system is configured for infusing fluid to a patient. The system includes a plurality of modular fluid infusion pumps that each has a connector for connecting to a modular programming unit or to one another. Systems and methods are configured for verifying that the connectors are reliably performing their functions or communicatively connecting the pumps to one another or to the programming unit.
US11844920B2 Microneedle immunotherapeutic multi-component system and a method for vaccination
A dissoluble microneedle drug delivery system includes a fixation component having an opening window area, and at least two replaceable and/or dissoluble inner matrices fitting into the window area one after another. The fixation component comprises an array of microneedles attached on its base, at least part of the microneedles being configured to fix the delivery system onto skin. The first inner matrix comprises a multitude of microneedles attached on its base, at least part of the microneedles configured to prepare the skin to vaccination by the subsequent second inner matrix. The second inner matrix is a vaccine/immunization matrix configured to replace the first inner matrix and comprising an array of microneedles attached on its base, at least part of the microneedles configured to deliver a vaccination. The system may include a microchannel network within at least one inner matrices for delivery of components regulating dissolution of the microneedles.
US11844919B2 Microneedle for local delivery of therapeutic agent
The disclosed subject matter relates to a cleavable microneedle for delivery of therapeutic agent, wherein the needle includes a longitudinal body having a detachable portion that comprises at least one therapeutic agent. The microneedle may be configured to administer the therapeutic agent to the inner ear of a subject. Also disclosed is a method for preparing a microneedle using two-photon polymerization lithography.
US11844912B2 Method for visualizing a catheterization guidewire
A guide wire configured for use with existing catheter mapping and navigation systems. The guide wire is made of electrically conductive material and coated in an electrically insulating material. An uncoated region is provided near the guide wire's distal tip. This uncoated region forms a conductive path between the metallic components of the guide wire and the surrounding tissue. The uncoated region effectively becomes an electrode for use in prior art mapping and navigation systems. The mapping and navigation system determines the position of the uncoated region.
US11844909B2 Guide catheter with reinforcing member
Example medical devices are disclosed. An example medical device includes an elongate member having a proximal end region, a distal end region and an outer surface. The medical device also includes a plurality of filaments braided together in a first braided pattern along a first braided region of the elongate member, wherein the plurality of filaments extend continuously to a second braided region along the elongate member, wherein the plurality of filaments along the second braided region form a second braided pattern different from the first braided pattern.
US11844907B2 Humidifiers for respiratory apparatus
A positive airway device is configured to deliver a pressurized flow of humidified respiratory gas to a patient's airways and includes a flow generator with a blower portion and a docking portion laterally adjacent to the blower portion. The docking portion is separated from the blower portion by a divider and comprises a cavity configured to laterally receive a humidifier tub. The humidifier tub comprises a first tub subsection with an air inlet opening and an air outlet opening and a second tub subsection. A flange extending outwardly from an outer surface of the humidifier tub forms a transition between the first and second tub subsections. The humidifier tub is configured so that when the humidifier tub is fully received by the docking portion, the first tub subsection is enclosed within the cavity and the second tub subsection remains outside the cavity.
US11844906B1 Oxygen-air blender for neonates
A portable oxygen-air blender including a gas distributor valve, a plurality of venturi valves, and an oxygen monitor. The gas distributor valve selectively routes the flow of oxygen from a compressed gas reservoir into one of several venturi valves to be blended with atmospheric air in a predetermined ratio. The blended oxygen-air mixture may be safely delivered to neonatal patients who require a specific concentration of oxygen to breathe. A monitoring system allows the user to verify concurrently that the patient is receiving the correct blend of oxygen and make adjustments to the patient's treatment.
US11844902B2 Gas washout vent for patient interface
A gas-washout vent includes a housing with a first wall with one or more passages through the wall configured to provide fluid communication with a portion of the patient interface system exposed to a therapy pressure. The passages include respective first openings on a first surface of the first wall. The housing at least partially defines a second opening in communication with ambient atmosphere. A diffusing material is located at least partially within the housing to be adjacent the first surface. A surface of the diffusing material facing the first surface is spaced away from the first surface by a gap that extends to provide a fluid communication between all of the first openings and between all of the first openings and the second opening. The housing is configured so that air is prevented from flowing out of the housing at all areas directly opposite each of the first openings.
US11844900B1 Apparatus, methods, and systems for administering a medication to a patient from a capsule using an atomizer
A method is disclosed for administering medication to conscious or unconscious patients using a device with a tubular chamber. The method involves the use of a device with a tubular chamber, wherein a liquid medication is contained within a capsule. The medication is atomized by activating an atomizer, thereby generating an atomized medication consisting of particles with a maximum diameter of four microns. The atomized medication is then dispensed into the tubular chamber. Using the device, the atomized medication is administered to the patient. In cases of unconsciousness, a resilient air bladder connected to the chamber is partially deflated, allowing air transfer into the chamber. This facilitates the administration of the atomized medication. This method enables effective medication delivery in various emergency scenarios, ensuring appropriate treatment even for unresponsive patients by providing a method of using a device with modular components.
US11844899B2 Virtual respiratory gas delivery systems and circuits
A respiratory gas delivery system monitors gas flow over the course of a breath in real time and uses this parameter to simulate, in whole or part, the function of a reference respiratory gas delivery system, in particular structural features, particularly structural components of parts of the reference system, to overcome a structural limitation of the reference system.
US11844898B2 System and method for detecting stroke in patients during pressure support therapy
A method of detecting stroke in a patient receiving a pressure support therapy includes: receiving data from one or more sensors structured to gather data related to patient respiration while receiving pressure support therapy from an airflow generator via a patient circuit; analyzing the data from the one or more sensors while pressure support therapy is provided to the patient; determining that the analyzed data from the one or more sensors is indicative of a patient experiencing respiratory changes indicative of a stroke; and responsive to said determining, triggering at least one alarm.
US11844896B2 Balanced ergonomic surgical handle
An ergonomic medical device handle which allows for multiple type grip styles and reduces operator fatigue by balancing the weight of the device about a fulcrum point. More particularly a laparoscopic suction irrigation device having its tubing centrally located to allow the handle to rest comfortably and balanced on the hand in any of the commonly used grips. This dramatically reduces the fatigue associated with holding devices for long periods of time.
US11844892B2 Device for establishing the venous inflow to a blood reservoir of an extracorporeal blood circulation system
A device for establishing venous inflow to a blood reservoir of an extracorporeal blood circulation system includes a restricting unit for gradually closing a venous inflow line and a vacuum unit for supplying vacuum to the blood reservoir. The device includes a control unit that supplies a first actuating signal to the restricting unit for restricting venous inflow to the blood reservoir and supplies a second actuating signal to the vacuum unit for establishing a degree of vacuum within the blood reservoir.
US11844888B1 Photonic corpuscular irradiator machine
A photonic corpuscular irradiator machine, having an irradiation chamber having an external wall, a top edge, a bottom edge, an internal wall, and a spiral ridge; and an ultraviolet irradiation lamp. A machine assembly has an irradiation chamber housing, a bar code scanner, a control panel, an automatic peristaltic pump, and an intensity dial; and further having first and second blood bags. The external wall and the internal wall define a peripheral channel between them, and the spiral ridge extends within the peripheral channel. Blood from the first blood bag travels through an inlet port and is forced upwardly in a spiral motion along the spiral ridge within the peripheral channel and exits from an outlet port to the second bag. The irradiation bulb within of the cavity irradiates ultraviolet light to the blood within the peripheral channel. The ultraviolet light treats blood containing COVID-19 and/or pathogens.
US11844886B2 Syringe with controllable breaking features
A syringe with structural features to accomplish one-handed aspiration as well as one-handed injection. The syringe includes one or more breaking points that are configured to break at predetermined locations in response to external forces being applied thereto. To assist in accountability, identification chips and/or codes are included to allow for the traceability of the syringe to potential sources of irresponsible dispensing of medical waste.
US11844885B2 Photocatalytic reactor for ventilation systems
A photocatalytic reactor for use in a heating, ventilation and/or air conditioning system, and comprises a longitudinal housing having a wall and allowing air or gas to pass through along the longitudinal direction of the longitudinal housing. A plurality of tubes are positioned in the longitudinal housing and arranged such that some outer tubes are positioned closer to the housing wall than some inner tubes. The tubes have their longitudinal axis parallel with the longitudinal axis of the longitudinal housing allowing the air or gas to pass along and through the tubes and the tubes comprise photocatalytic material in or on their tube walls. The system comprises an irradiation system for irradiating the photocatalytic material for inducing catalytic action. The irradiation system and plurality of tubes are configured so that upon irradiating by the irradiation system photocatalytic material of the outer tubes and inner tubes is irradiated.
US11844882B2 Vehicle-mounted intelligent fragrance generator
A vehicle-mounted intelligent fragrance generator includes a casing and a plurality of essence boxes. The casing includes a base. Each essence box includes an outer sleeve, an inner sleeve, an essence block and a fragrance front cover, the outer sleeve has a protrusion, and the protrusion is disposed at a front end portion of an inner wall of the outer sleeve. A rear end of the inner sleeve is a closed end, a front end is an open end, and the front end of an outer wall of the inner sleeve is provided with an anti-rotation strip. The outer sleeve is fixed inside the base, the outer sleeve, the inner sleeve and the essence block are sequentially sleeved, the front end of the inner sleeve protrudes from the outer sleeve and extends out of the base, and the anti-rotation strip is clamped on the protrusion of the outer sleeve.
US11844881B2 Composite material with high dielectric constant and use in biocompatible devices
The present invention is directed to a composite material with a high dielectric constant. In certain embodiments, the composite material of the invention is biocompatible and is used in an implantable medical device, such as an implantable antenna, probe, sensor or electrode. In certain embodiments, the present invention comprises a biocompatible conductive or semi-conductive filler comprising filler particles dispersed within a biocompatible electrically insulating material. The filler particles may comprise an electrically insulating coating.
US11844877B2 Devices and methods for nerve regeneration
A nerve regeneration device comprising a bioresorbable conduit and a matrix contained therein having elongate pores aligned with the longitudinal axis of the conduit. The matrix comprises collagen, fibronectin, laminin-1, and laminin-2, wherein the amount, by weight, of laminin-1 or laminin-2 is greater than the amount of fibronectin in the matrix.
US11844872B2 Mobile sanitization systems and methods
A mobile sanitization system includes a movable trolley having an arm that is extendable between a first position in which the arm is in a collapsed state and a second position in which the arm is extended outwardly. The mobile sanitization system includes at least one ultraviolet light source coupled to the arm that is configured to illuminate to disinfect. The mobile sanitization system includes a source of liquid disinfectant and at least one nozzle fluidly coupled to the source of liquid disinfectant. The nozzle is coupled to at least one of the trolley and the arm, and the nozzle is configured to dispense the liquid disinfectant. The mobile sanitization system includes a spray wand removably coupled to the trolley and fluidly coupled to the source of liquid disinfectant. The spray wand is removable from the trolley to dispense the liquid disinfectant to disinfect a targeted area.
US11844869B2 Aqueous wound healing formulation
The present invention relates to a water resistant wound cover with high comfort and good air permeability. In particular, the present invention relates to an aqueous wound healing formulation comprising a water-soluble or a water-dispersible polymeric material that does not sting when applied to a minor injury to the skin.
US11844863B2 Oral delivery system for bioactive agents
The present invention relates to a functional feed and an oral delivery system for delivery of bioactive macromolecules. The oral delivery system comprises ethylenediammonium alginate which is a vehicle for delivery of macromolecular drugs. The oral delivery system according to the present invention is particularly suitable for use in combination with functional feeds in fish.
US11844860B2 Pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa
A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa as active ingredients and one or more excipients. Once dispersed in an aqueous medium, melevodopa is completely dissolved, and carbidopa is present as nanoparticles.
US11844855B2 Sun care composition for whitening the skin, use of the sun care composition, and process of manufacture of the sun care composition
The present invention relates to a cosmetic composition to be used on the skin comprising the combination of a particular whitening system, a UVA filter system, and a combination of antioxidants for effectively whitening the skin, in particular the skin of the face, while also protecting these materials from the damages caused by UVA radiation.
US11844852B2 Skincare product and method of preparation thereof
The core active components of the present composition, termed as de-ironizing inducers (DII), has a reducing agent and a precipitating agent. Molar ratios of the reducing agent with the precipitating agent range from 1:3-6 and the core components in the skincare product range from 0.1% to 10% w/w. The pH value of the skincare product is between 6.6 and 7.4. The skin care products can safely and effectively 5 remove iron in the skin, which has been shown to accelerate the visible signs of aging. The core components can also be used in combination with conventional skincare product compounds to achieve better anti-aging effects.
US11844851B2 Stannous salt and sodium tripolyphosphate oral care compositions and methods
Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.
US11844850B2 Water in oil type cosmetic composition for preventing syneresis
The present disclosure provides a water in oil type cosmetic composition that prevents syneresis and exhibits favorable stability. A water in oil type cosmetic composition for preventing syneresis of the present disclosure is characterized by containing a compound which is solubilized by being neutralized as an active component. In addition, a preferred embodiment of the water in oil type cosmetic composition for preventing syneresis of the present disclosure is characterized by the compound which is solubilized by being neutralized being a water soluble compound which has a sulfonic acid group. Further, a water in oil type cosmetic of the present disclosure is characterized by containing: a compound which is solubilized by being neutralized; a gelling agent; water; and a powder component; the viscosity of the water in oil cosmetic being greater than or equal to 7000 mPa·s.
US11844848B2 Photocurable dental composition
The present invention relates to a photocurable dental composition comprising a specific polymerization initiator system containing the combination of a photoinitiator compound and a coinitiator compound being a sulfinate compound or a sulfonate compound. The present invention also relates to the use of this polymerization initiator system in a photocurable dental composition.
US11844847B2 Sulfur-containing polymerizable monomer and use thereof
A compound (A) is represented by the formula (1): wherein R1 is a hydrogen atom or an alkali metal atom, R2 is a hydrogen atom or an alkali metal atom, R3 is a hydrogen atom or a methyl group, Z is a divalent or trivalent organic group, and the lines consisting of a solid line and a broken line bonded to Z represent a single bond or a double bond.
US11844846B2 Styrylbenzothiazole derivatives and uses in imaging methods
This disclosure relates to styrylbenzothiazole derivatives for use as in vivo imaging agents for the diagnosis of Parkinson's disease (PD) or other degenerative disorders or conditions of the central nervous system. Early diagnosis is particularly advantageous as neuroprotective treatment can be applied to healthy neural cells to delay or even prevent the onset of debilitating clinical symptoms.
US11844843B2 Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
Aspects of the disclosure relate to complexes comprising a muscle-targeting agent covalently linked to a molecular payload. In some embodiments, the muscle-targeting agent specifically binds to an internalizing cell surface receptor on muscle cells. In some embodiments, the molecular payload inhibits expression or activity of DUX4. In some embodiments, the molecular payload is an oligonucleotide, such as an antisense oligonucleotide or RNAi oligonucleotide.
US11844837B2 Compositions of a polyorthoester and an organic acid excipient
Delivery systems and compositions comprised of a biodegradable polyorthoester polymer, an organic acid excipient, and a basic drug are described, along with related methods.
US11844834B2 Vaccine adjuvant
There is provided a novel vaccine adjuvant, and more specifically, a vaccine adjuvant for stimulating a T lymphocyte-specific immune response, which includes an IL-12 protein and an IL-21 protein as active ingredients, or includes the polynucleotide encoding an IL-12 protein and the polynucleotide encoding an IL-21 protein as active ingredients.
US11844832B2 Inorganic polyatomic oxyanions for protecting against antigenic damage during pathogen inactivation for vaccine production
Provided are methods for rapidly inactivating a pathogen, or for producing a vaccine composition containing an inactivated noninfectious pathogen having retained antigenicity and/or immunogenicity, comprising exposing the pathogen to a chemical inactivating agent (e.g., one or more chemical oxidizing, alkylating or crosslinking agents) in the presence of inorganic polyatomic oxyanions in an amount and for a time sufficient to render the pathogen noninfectious while enhancing retention of pathogen antigenicity and/or immunogenicity relative to that retained by contacting the pathogen with the chemical inactivating agent alone. The methods are broadly applicable to pathogens having RNA or DNA genomes (e.g., including viruses, bacteria, fungi, and parasites). Also provided are vaccine compositions (medicaments) containing a pathogen inactivated by exposure to an inactivating agent in the presence of elevated concentrations of inorganic polyatomic oxyanions, and methods for eliciting an immune response in a subject by administering the vaccine compositions.
US11844828B2 Vaccine
The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, the present invention relates to sized Streptococcus pneumoniae serotype 6A capsular polysaccharides, in particular Streptococcus pneumoniae serotype 6A capsular polysaccharides having the average size (e.g. Mw) of the Streptococcus pneumoniae serotype 6A capsular polysaccharide is between 100-1000 kDa, suitably conjugated to a carrier protein.
US11844827B2 Genetically modified anti-third party central memory T cells and use of same in immunotherapy
An isolated cell having a central memory T-lymphocyte (Tcm) phenotype, the cell being tolerance-inducing cell and capable of homing to the lymph nodes following transplantation, the cell being transduced to express a cell surface receptor comprising a T cell receptor signaling module is disclosed. Methods of generating same and using same are also disclosed.
US11844825B2 Method of treating mucopolysaccharidosis type IVA
Disclosed are methods and compositions for determining immunodominant peptides of target enzymes used in enzyme replacement therapy for lysosomal storage disorders. More specifically disclosed are immunodominant peptides for N-acetylgalactosamine-6-sulfatase (GALNS). Also disclosed are methods of inducing oral tolerance towards a target enzyme through oral administration of immunodominant peptides prior to commencing enzyme replacement therapy. More specifically disclosed is a method of inducing oral tolerance for GALNS, by orally administering specific immunodominant peptides for GALNS; in subjects suffering from mucopolysaccharidosis type IVA prior to commencing enzyme replacement therapy using GALNS.
US11844823B2 Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof
The present invention relates to pharmaceutical aerosols comprising a β-hairpin peptidomimetic of formula cyclo(-OctG-Glu-Thr-Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-DPro-Pro-), or a pharmaceutically acceptable salt thereof, having inhibitory activity against human neutrophil elastase. It further relates to solid or liquid pharmaceutical compositions and kits for preparing and administering such aerosols. The invention can be used for the prevention, management or treatment of pulmonary diseases, such as alpha-1 antitrypsin deficiency (AATD), cystic fibrosis (CF), non-cystic fibrosis bronchiactasis (NCFB), or chronic obstructive pulmonary disease (COPD), or infections, or diseases, or conditions of the lungs, being mediated by or resulting from human neutrophil elastase activity. Thus, the invention further relates to a pharmaceutical composition or a pharmaceutical aerosol comprising the active compound cyclo(-OctG-Glu-Thr-Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-DPro-Pro-), or any pharmaceutically acceptable salt thereof, for use in a method for the prevention, management or treatment of diseases or conditions of the lungs being mediated by or resulting from human neutrophil elastase activity in a subject.
US11844817B2 Inhaled respiratory probiotics for lung diseases of infancy, childhood and adulthood
The respiratory microbiomes of neonates and those with bronchopulmonary disease have been characterized. Provided are probiotic compositions, which can include at least one living bacterial strain and at least one killed bacterial strain, that can comprise a combination of Lactobacilli species, 5 that when delivered to the bronchi or lungs of a patient can provide a reduction in the symptoms of a bronchopulmonary disease.
US11844814B2 Methods for expansion or depletion of T-regulatory cells
The invention features methods of producing compositions enriched in Tregs and methods for treating immunological disorders using these compositions. The invention also features methods for producing compositions enriched in lymphocytes and depleted of Tregs and the use of these compositions in the treatment of proliferative disorders.
US11844812B2 Selenoprotein P for prediction of a first cardiovascular event
Subject of the present invention is a method for assessing a risk for getting a first cardiovascular event or assessing the risk for cardiovascular mortality in a subject, comprising: a) determining the level and/or the amount of Selenoprotein P and/or fragments thereof in a sample of said subject; b) correlating the determined level and/or the amount of Selenoprotein P and/or fragments thereof with the risk for getting a first cardiovascular event or assessing the risk for cardiovascular mortality in said subject.
US11844810B2 Enhancement of vaccine efficacy and antibiotic efficacy
Disclosed herein are compositions and methods for modulating a macrolide antimicrobial, modulating an immune function, increasing the effectiveness of an antibiotic, and/or increasing the number and effectiveness of alveolar macrophages in treating a vertebrate animal. The method comprises feeding to the animal a feed composition comprising (1, 3), (1, 6), beta-glucans and optionally mannans to increase the number of alveolar macrophage cells, and administering a macrolide antibiotic to the animal.
US11844808B2 Methods and compositions for treating pre-eclampsia
Methods and compositions using trehalose or a derivative or prodrug thereof for treating pre-eclampsia in a subject are disclosed.
US11844806B2 Compositions comprising acetylsalicylic acid and a phosphate salt
The present invention relates to a novel two-component system comprising acetylsalicylic acid (ASA) and which is particularly useful in providing an aqueous solution of ASA for immediate peroral administration.
US11844804B2 Administration of testosterone compositions
The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.
US11844797B1 Combination of dextromethorphan and bupropion for treating depression
This disclosure relates to administration of a combination of: 1) about 100-110 mg, about 104-106 mg, or about 105 mg of bupropion hydrochloride, or a molar equivalent amount of a free base form or another salt form of bupropion; and 2) about 40-50 mg, about 44-46 mg, or about 45 mg of dextromethorphan hydrobromide, or a molar equivalent amount of a free base form or another salt form of dextromethorphan in certain patient populations, such as patients having moderate renal impairment, patients having mild or moderate hepatic impairment, patients receiving a concomitant strong CYP2D6 inhibitor, patients who are known CYP2D6 poor metabolizers, those in need of an NMDA antagonist that does not cause dissociation, and those at risk of QT prolongation.
US11844796B2 Immediate release abuse-deterrent granulated dosage forms
Described are immediate release oral dosage forms that contain abuse-deterrent features. In particular, the disclosed dosage forms provide deterrence of abuse by ingestion of multiple individual doses. In addition, the disclosed dosage forms provide protection from overdose in the event of accidental or intentional ingestion of multiple individual doses.
US11844795B2 Combination therapy for cancer treatment
Combination therapies for treating cancer comprising administration of a topoisomerase-1 inhibitor and a PARP inhibitor are provided. The topoisomerase-1 inhibitor can be delivered as a liposomal formulation that provides for prolonged accumulation of the topoisomerase-1 inhibitor within a tumor relative to outside of the tumor. Therapeutic benefit can thereby be obtained by delaying the administration of the PARP inhibitor after each administration of a liposomal irinotecan formulation until the accumulation of the topoisomerase inhibitor in the tumor is sufficiently greater than outside the tumor to result in increased efficacy of the PARP inhibitor and topoisomerase inhibitor within the tumor, while reducing the peripheral toxicity of the combination therapy. The therapies disclosed herein are useful in the treatment of human cancers with solid tumors, including cervical cancer.
US11844790B2 Methods of treating hidradenitis suppurativa
Provided herein are methods for treating a subject suffering from a cutaneous neutrophilic inflammatory disease comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein each variable position is as defined herein. In some embodiments, the cutaneous neutrophilic inflammatory disease is Hidradenitis suppurativa (HS).
US11844788B1 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea
Provided herein are low impurity compositions comprising a compound represented by Formula (I): which are useful in the treatment of disorders related to the activity of the c-KIT and PDGFRα kinases, and oncogenic forms thereof.
US11844786B2 Uses of combinations (+)-α-dihydrotetrabenazine and (−)-α-dihydrotetrabenazine in methods of treating movement disorder
The invention relates to pharmaceutical compositions containing both (+)-α-dihydrotetrabenazine and (−)-α-dihydrotetrabenazine and their therapeutic uses, for example in the treatment of movement disorders, such as Tourette's syndrome.
US11844785B2 3-(phenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide compounds for the management of CFTR protein mediated diseases
This disclosure relates to methods of treating or preventing cystic fibrosis transmembrane conductance regulator (CFTR) mediated diseases such as cystic fibrosis, chronic obstructive pulmonary disease, chronic pancreatitis, chronic bronchitis, asthma, mucus formation, comprising administering an effective amount of a 3-(phenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide compound, salt, or derivative thereof to a subject in need thereof. In certain embodiments, the 2-amino-N′-benzylidene-acetohydrazide compound is 3-(3,5-dibromo-4-hydroxyphenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide.
US11844783B2 Formulations of bendamustine
Long term storage stable bendamustine-containing compositions are disclosed. The compositions can include bendamustine or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable fluid which can include in some embodiments PEG, PG or mixtures thereof and an antioxidant or chloride ion source. The bendamustine-containing compositions have less than about 5% total impurities, on a normalized peak area response (“PAR”) basis as determined by high performance liquid chromatography (“HPLC”) at a wavelength of 223 nm, after at least about 15 months of storage at a temperature of from about 5° C. to about 25° C.
US11844782B2 Aqueous composition comprising dantrolene
An aqueous composition includes either dantrolene or a pharmaceutically acceptable salt thereof and a cyclodextrin derivative, with the pH of the aqueous composition greater than 7. A powder can be obtained by drying the composition. The powder can be included in a kit.
US11844780B2 Chlorinated tetralin compounds and pharmaceutical compositions
The present disclosures are directed to chlorinated tetralin compounds and pharmaceutical compositions.
US11844776B2 Composition for treatment and/or prevention of peripheral nerve disorder
The present invention provides a means for treating and/or preventing peripheral nerve disorder by facilitating regeneration of peripheral nerves. Specifically, the present invention provides a composition for treating and/or preventing peripheral nerve disorder comprising a compound represented by the general formula (I): wherein R1 is lower alkyl substituted with lower alkoxy, lower alkyl substituted with a heterocyclic group, a heterocyclic group, or a group represented by the formula (IIa): R4O—R5m  (IIa) wherein R4 is lower alkyl, R5 is lower alkylene, and m is an integer of 1 to 6; R2 is lower alkyl optionally substituted with phenyl; and R3 is lower alkyl optionally substituted with halogen, lower alkoxy, or phenyl; condensed polycyclic hydrocarbon; or hydrogen.
US11844773B2 Solid solution compositions and use in chronic inflammation
The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
US11844772B2 Method for treating rhabdoid tumors
The methods include treating atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene. Some embodiments relate to treatment of atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene to a population or subject expressing SMARCB1.
US11844766B2 ExPEC glycoconjugate vaccine formulations
Compositions and methods for inducing an immune response against extra-intestinal pathogenic Escherichia coli (ExPEC) are described. In particular, multivalent vaccines containing O-antigen polysaccharide covalently bound to an exotoxin A of Pseudomonas aeruginosa (EPA) carrier protein that can withstand multiple environmental stresses are describe.
US11844764B2 Agitation process for preparing a carbetocin drug product
The present disclosure includes a method of making an improved carbetocin drug product. The disclosed method for making an improved carbetocin drug product comprises agitating a carbetocin preparation containing an aqueous solution of carbetocin and one or more excipients for a period of time to initiate the formation of aggregate-forming solids and filtering off the aggregates that form before further processing the remaining carbetocin into a final drug product. The present disclosure also relates to an improved carbetocin drug product, wherein the drug product is substantially free of aggregate-forming solids. The disclosed carbetocin drug product can be used for the treatment of a neurodevelopmental disorder, such as Präder-Willi syndrome. Additionally, the disclosed carbetocin drug product shows content uniformity of carbetocin over long periods of time before and after one or more freeze/thaw cycles, provides enhanced convenience and patient compliance, and/or are highly concentrated.
US11844757B2 Organic compounds
The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving the 5-HT2A receptor, the serotonin transporter (SERT), pathways involving the dopamine D1 and D2 receptor signaling system, and/or the μ-opioid receptor.
US11844755B2 Compounds and their use as therapeutically active substances in the treatment and/or reducing signs or symptoms of diseases involving the retinal pigment epithelium
A method of treating and/or preventing disease wherein retinal pigment epithelium, including administering compound of formula (I) or pharmaceutically acceptable salt, racemic mixture, corresponding enantiomer or, if applicable, corresponding diastereomer, wherein: X is either NH or O, R11, R12 and R13 are independently selected from consisting hydrogen group, fluoro, chloro, trifluoromethyl, methyl and difluoromethoxy, A is selected from consisting residue group of formula (II)-(VII) or (VIII) “*” denotes point of attachment to molecule remainder, and R2, R3, R4, R5, R2I, R3I, R4I, R5I, R2II, R3II, R4II, R5II, R2III, R3III, R4III, R5III, R2IV, R3IV, R4IV, R5IV, R2V, R3V, R4V, R5V, R2VI, R3VI, R4VI and R5VI are independently selected from hydrogen consisting group, linear or branched alkyl having 1-3 carbon atoms, fluoro, chloro, bromo, methoxy, ethoxy, propoxy, trifluoromethyl, 2,2,2-trifluoroethyl and difluoromethoxy and R6 is selected from hydrogen consisting group, linear or branched alkyl having 1-3 carbon atoms, trifluoromethyl, and 2,2,2-trifluoroethyl.
US11844754B2 Methods for treatment of Parkinson's disease
Disclosed is a method for the treatment of a neurological or movement disorder, e.g., Parkinson's disease, in an individual in need thereof, by parenteral administration of levodopa, a levodopa salt, a levodopa prodrug, or any combination thereof, and a dopa decarboxylase inhibitor (DDCI), such as carbidopa, a carbidopa salt, a carbidopa prodrug, benserazide or any combination thereof, concomitantly with oral administration of levodopa, a DDCI, such as carbidopa, benserazide, or any combination thereof.
US11844752B2 Deodorant compositions
A deodorant stick comprising: at least about 25% of a liquid triglyceride; at least one antimicrobial; a primary structurant with a melting point of at least about 50° C.; and less than 8% of secondary structurants having a melting point of at least about 60° C.; said stick being free of an aluminum salt; and said stick having a hardness from about 80 mm*10 to about 140 mm*10, as measured by penetration with ASTM D-1321 needle.
US11844750B2 Syringe pumps for automatic drug compounders
Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes controllable fluid pathways. The cartridge may include a syringe pump for moving fluid and/or gas, and one or more syringe valves or rotary valves for controlling which of the controllable fluid pathways is open for flow of the fluid and/or gas.
US11844743B2 CPR chest compression device with releasable base member
A CPR device having a base member configured to be placed underneath a patient, a chest compression mechanism configured to deliver CPR chest compressions to the patient, a support leg configured to support the chest compression mechanism at a distance from the base member, a clamp mechanism coupled to the support leg, and a release mechanism coupled to the support leg and the clamp mechanism. The clamp mechanism is configured to attach the support leg to a lock component of the base member in a latch-closed configuration and to release the support leg from the lock component in a latch-open configuration. The clamp mechanism is further configured to transition from the latch-closed configuration to the latch-open configuration when the lock component of the base member impacts an external portion of the clamp mechanism without the release mechanism being pulled away from the base member.
US11844735B2 Wheelchair push handle assembly
A wheelchair push handle assembly incorporating a chair back having right and left loops, and an upper end; right and left upwardly opening tubes respectively received within the right and left loops; right and left eyes opening the right and left tubes, wherein the eyes overlie the chair back's loops; right and left “L” members having hollow bored columns within the right and left tubes; right and left series of apertures opening the right and left columns' hollow bores; right and left series of latch pins received within the right and left series of apertures; and right and left series of springs mounted within the right and left columns' hollow bores, wherein each spring is connected to one of the latch pins, wherein one of the right latch pins engages the right eye, and wherein one of the left latch pins engages the left eye.
US11844728B1 Method and apparatus for a flat, single piece, foldable, complete, medical face shield
The present invention relates to a light-weight, self-contained, one piece, ventilated, washable, disposable, face shield for the protection of regions penetrable membranes, such as the eyes, nose and mouth of medical personnel, essential workers and the general public from exposure to infectious, and/or hazardous pathogens carrying fluids and particulate materials such as the Coronaviridae family of viruses including COVID-19. Some embodiments include a front facing transparent face plate, a plurality of adjustable flaps to customize the angle of protection, a mechanism to separate the transparent front facing face plate from the user's forehead, an attaching and sizing mechanism to conform to the user's head. Some embodiments may use materials that inherently, or through the application of special coatings, provide additional optical protections.
US11844725B2 Visually traceable vitrectomy probe cap
A vitrectomy probe with a light emitting, visibly discrete traceable probe cap. The light emitting, visibly discrete character of the probe cap may aid a surgeon in tracing the end of a needle of the vitrectomy during a vitrectomy procedure. The probe cap may be of a biocompatible polymer accommodating phosphorescent pigment or of another suitable light source.
US11844724B2 Method for eye lens removal using cavitating microbubbles
A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification.
US11844723B2 Dispenser for discharging pharmaceutical liquids
A dispenser for discharging pharmaceutical liquids in the form of individual drops, having a liquid store, a pump device with a pump chamber with a variable volume, and a dispensing opening. The dispenser additionally has a membrane part which delimits the pump chamber on one side and which changes the volume of the pump chamber by moving and/or deforming. The dispenser has a housing, within which the pump device is provided, and an actuation button movable relative to the housing between a non-actuated starting position and an actuated end position to move or deform the membrane part and to decrease the size of the pump chamber to discharge the liquid. The membrane part is secured to the housing and to the actuation button. The pump chamber achieves a high degree of compression and a toggle switch is used as the actuation button.
US11844720B2 Method and system to reduce the likelihood of dental caries and halitosis
A method to facilitate the growth of desired bacteria in a human's mouth to reduce the likelihood of dental caries and halitosis and other oral diseases, and for inhibiting oral biofilm formation, gingivitis, periodontitis and halitosis via the employment of one or more probiotic bacterial, bioactive flavonoid, and zinc compound compositions effective in providing prevention and treatment options.
US11844719B2 Breathing assist device
Apparatus for providing breathing assistance, the apparatus including a body for positioning within an oral cavity of a user, the body defining at least one first opening for allowing airflow between lips of the user, two second openings provided in the oral cavity to allow air flow into and out of a posterior region of the oral cavity and two channels, each channel connecting a respective second opening to the at least one first opening and each channel passing at least one of at least partially along the buccal cavity and at least partially between the teeth to thereby provide an airway for the user, the airway at least partially bypassing the nasal passage and acting to replicate a healthy nasal passage and pharyngeal space.
US11844718B2 Medical device having a monitor mechanically and electrically attachable to a medical appliance
A medical device includes a monitor having a processor for processing data and a memory adapted to store the data, and a medical appliance attachable to skin of a user. The medical appliance includes an adhesive, an electrode assembly coupled to the medical appliance and located distal to the adhesive, a top layer coupled to the medical appliance and located distal to the electrode assembly, and a monitor interface connected to the top layer. The monitor interface includes a mechanical coupling part to mechanically attach the monitor to the medical appliance and an electrical coupling part with a terminal that electrically connects the monitor to the electrode assembly when the monitor is attached to the medical appliance.
US11844716B2 Syndesmosis reduction device and method of use
An improved syndesmosis reduction device has a wrap of elastic material extending a length L from a first end to a second end with an open window or slot positioned in an intermediate portion of the wrap spaced from the ends. The wrap is configured to achieve a reduction of an injured ankle and is facilitated by the elastic nature of the ankle wrap. The reduction is facilitated by circumferentially wrapping the wrap from a leg to a foot or vice versa in a compressive fashion by securing the first end by wrapping and stretching the wrap to the second end. The window or slot is to permit an incision at the ankle for hardware placement without the need to remove the wrap and without loss of the reduction achieved.
US11844715B2 Adjustable neck support
An adjustable neck support includes a neck holder front support, a left side plate, a right side plate, a lower jaw holder plate, and a height adjustment knob. The left side plate is movably connected at a left end of the neck holder front support, the right side plate is movably connected at a right end of the neck holder front support, the lower jaw holder plate is connected between the left side plate and the right side plate, and the height adjustment knob is mounted on the neck holder front support. The height adjustment knob includes an operating cover and a winding post connected to the operating cover, the winding post being mounted in the neck holder front support. The adjustable neck support provided by the application is smooth in height adjustment operation, easy to operate, and long in service life.
US11844712B2 Intravascular stent having high fatigue performance
This invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more links. A Y-shaped member is comprised of a U-shaped member and a link having a curved portion and a straight portion to improve the flexibility and thereby improve the fatigue performance of the Y-link junction.
US11844707B2 Adjustable stiffness prosthetic foot
A foot prosthesis that includes at least one spring element, an attachment member, and a heel member. The at least one spring element has a toe end portion, a heel end portion, an upper surface, and a lower surface. The attachment member is mounted to the upper surface and is configured to connect the foot prosthesis to a lower limb prosthesis component. A position of the attachment member is adjustable along a length of the at least one spring element. The heel member is mounted below the lower surface of the at least one spring element, and a position of the heel member is adjustable along the length of the at least one spring element.
US11844701B2 Guider for spinal operation and cage therefor
Proposed are a guider for a spinal operation and a cage therefor. The guider includes a sliding portion configured to guide a cage for a spinal operation and a holder to a surgical site, a head of the sliding portion being inserted into a human body region where a surgical incision is made for the spinal operation, and the cage for a spinal operation being combined with the holder; a support portion combined with one side of the sliding portion and thus supporting the sliding portion; and a handle combined with the support portion.
US11844691B2 Partially-covered prosthetic valves
An implant includes an expandable frame having a continuous lumen and has (a) an upstream row of upstream cells and (b) at least two downstream rows of downstream cells. An upstream portion of each cell is shaped by ascending and descending struts that form a respective peak that points in an upstream direction. A valve member is disposed within the lumen and facilitates unidirectional flow of blood from an upstream end of the frame to a downstream end of the frame. A covering has (i) a first portion entirely covering an outer surface of a downstream row of downstream cells, and (ii) a second portion partially covering an outer surface of an upstream row of downstream cells. Outer surfaces of the peaks of the upstream row of downstream cells are disposed upstream of an upstream end of the covering at the outer surface. Other embodiments are also described.
US11844685B2 In vivo tissue engineering devices, methods and regenerative and cellular medicine employing scaffolds made of absorbable material
Tissue engineering devices and methods employing scaffolds made of absorbable material for use in the human body for tissue genesis and regenerative and cellular medicine including breast reconstruction and cosmetic and aesthetic procedures and supplementing organ function in vivo.
US11844679B2 Interventional device having an integrated embolic filter and associated methods
A percutaneous transluminal angioplasty device, comprising an elongated catheter, an interventional device operably coupled to the proximal end of the catheter, a filter operably coupled to the distal end of the catheter, the filter movable between a collapsed and deployed position, and an actuator wire for deploying the collapsing the filter. At least a portion of the actuator wire extends within the catheter. The filter comprises a filter chassis comprising a movable collar a fixed collar and a tubular braided scaffolding coupled between the movable collar and the fixed collar. The filter chassis also comprises a filter membrane coupled to the tubular braided scaffolding.
US11844676B2 Personal hygiene product
A personal hygiene product for maintaining dryness in the intergluteal cleft is provided. The personal hygiene product may include an absorbent substrate having a proximal end and a distal end, and a tether extending through the absorbent substrate, the tether having a first end and a second end, the first end extending past the absorbent substrate proximal end, the second end extending past the absorbent substrate distal end.
US11844675B1 Surgical sponge
An improved surgical sponge having a contrast agent, such as bismuth beads, secured to the sponge material in a unique pattern of a type not found in nature or in human anatomy. The unique pattern is preferably spaced dots or circles having various sizes and spacing, potentially arranged in a matrix of rows and columns. The desired unique pattern is arranged such that the dots or other non-natural shapes are large enough to remain visible, while small enough to avoid adversely affecting the pliability and absorption of the sponge.
US11844672B2 Wound care devices, apparatus, and treatment methods
A wound care device for delivering topical oxygen therapy, negative pressure wound therapy, and a low intensity vacuum therapy for treatment of a wound. The wound care device may include an oxygen supply mea, an oxygen consuming mea, a vacuum pump and motor, a pressure sensor, and a power supply and electronic controls. A dressing may be connected to the wound care device for administering topical continuous oxygen therapy and simultaneous negative pressure wound therapy to a wound. A canister or exudate trap may be positioned between the dressing and the vacuum supply port of the vacuum pump to collect and store exudates from the wound. The canister may be combined with the dressing.
US11844668B2 Medical devices for generating heat and methods of treatment using same
A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.
US11844659B2 Denture or removable dental prosthetic made from composite material
A curable composite material containing nanodiamonds, denture bases and other dental prosthetics made from the composite material and methods for treating dental stomatitis using these prosthetics.
US11844656B2 Ultrasound diagnostic apparatus, method of controlling ultrasound diagnostic apparatus, and non-transitory computer-readable recording medium storing therein computer-readable program for controlling ultrasound diagnostic apparatus
An ultrasound diagnostic apparatus includes: a hardware processor that search for a blood vessel position of a subject in a tomographic image and automatically setting a region corresponding to the blood vessel position detected in the tomographic image as a measurement region for generating a Doppler image. In a case where a measurement region has been already set or in a case where a specified position specified by a user exists when the hardware processor automatically sets the measurement region, the hardware processor executes processing of searching for the blood vessel position such that the measurement region is automatically set near the measurement region that has been already set or the specified position.
US11844655B2 Method for estimating ventricular volume
A method for estimating a ventricular volume is provided and includes: obtaining a left ventricular mask image corresponding to a heart ultrasound image, where the left ventricular mask image is a binary image; finding 3 reference point pixels in the left ventricular mask image, where each of the reference point pixels has a first value, each of the reference point pixels is surrounded by N surrounding pixels, and the surrounding pixels of each of the reference point pixels include N1 first surrounding pixels with the first value and N2 second surrounding pixels with a second value; estimating a left ventricular volume corresponding to the heart ultrasound image based on the reference point pixels.
US11844653B2 Probe and ultrasound diagnostic device using the same
To provide a probe including a TGC circuit therein. The probe includes a plurality of receive circuits. Each receive circuit includes: an ultrasound transducer; a transmit/receive switch; a variable attenuator; a first capacitor; and an amplifier. The ultrasound transducer converts the receive signal into a ground level electric signal and outputs the ground level electric signal as a first output signal. The transmit/receive switch is connected to a first signal line, and switches depending on whether to output the first output signal output from the ultrasound transducer to the first signal line. The variable attenuator includes a control terminal and two terminals, and changes a resistance value between the two terminals other than the control terminal based on a control signal input to the control terminal. The amplifier has an input terminal connected to the first capacitor and includes at least an amplifier circuit configured to amplify an electric signal of the first signal line and output the amplified electric signal to a second signal line. In the variable attenuator, one of the two terminals other than the control terminal is connected to the first signal line, and the other terminal is connected to the ground via a second capacitor different from the first capacitor.
US11844651B2 Analyzing apparatus and analyzing method using distribution information
An analyzing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to obtain pieces of Doppler image data in a time series rendering a blood flow in an analysis target formed in a blood vessel. The processing circuitry is configured to analyze the pieces of Doppler image data in the time series and to calculate an index value based on temporal changes in a first blood flow signal intensity level in a first region of interest including the blood flow in the analysis target.
US11844647B2 Ultrasound catheter with adjustable apertures for multi-plane imaging
For intraluminal ultrasound probes, two long-thin arrays (e.g., 1D arrays) are provided in the intraluminal ultrasound probe for bi-plane imaging. The arrays are rotatable relative to each other so that during insertion the arrays align to be long and thin, allowing the shaft of the probe to be narrow. For bi-plane imaging after insertion, one array is rotated relative to the other array, defining two non-parallel imaging planes.
US11844644B2 Systems and methods for determining a heart rate of an imaged heart in an ultrasound image feed
The present embodiments relate generally to systems, methods, and apparatus for determining a heart rate of an imaged heart in an ultrasound image feed. A plurality of ultrasound images can first be acquired. For each ultrasound image of the plurality of ultrasound images, the image can be divided into a plurality of regions; where each region is positioned so that the region corresponds to a substantially similar region location present across the plurality of ultrasound images. For each region location on each of the plurality of ultrasound images, a statistical calculation on image data of the region location can be performed. For each region location, a frequency of change in the statistical calculation over the plurality of ultrasound images can then be determined. The region location having a dominant determined frequency of change in the statistical calculation (over the plurality of ultrasound images) can be identified as a region of interest (ROI). The heart rate can be calculated based on the determined frequency of change of the ROI.
US11844642B2 Treatment system, calibration method, and storage medium
A treatment system of embodiments includes an imaging system including one or more radiation sources and a plurality of detectors, a first acquirer, a second acquirer, a first deriver, a second deriver, and a calibrator. The radiation sources radiate radiation to an object in a plurality of different directions. The plurality of detectors detect the radiation at different positions. The first acquirer acquires images based on the radiation. The second acquirer acquires position information of a first imaging device in a three-dimensional space. The first deriver derives the position of the object in the images. The second deriver derives the position of a second imaging device in the three-dimensional space based on the position of the object in the images, the position of the first imaging device, and the like. The calibrator performs calibration of the imaging system based on a derivation result of the second deriver.
US11844638B1 Radiation shielding eye mask and method of use
An eye mask apparatus and method of use for protecting a patient's eyes during radiography has a lead vinyl sheet with a perimeter configured to completely cover the patient's eyes. The lead vinyl sheet has a first side and second side with a trim portion extending around the perimeter. The trim portion extends inward over the first and second sides. A retaining band coupled at a first attachment point and a second attachment point is configured to hold the eye covering portion against the patient's eyes when the mask is worn. To protect a patient's eyes during radiography, a lead vinyl sheet having at least 0.87 mm thickness, 0.125 mm lead equivalent value, and 2.18 kg/m2 weight is provided and formed into a shape with the width at least twice the height to cover both eyes. The lead vinyl sheet is placed over the patient's eyes prior to radiography.
US11844636B2 Dose reduction for medical imaging using deep convolutional neural networks
A method of reducing radiation dose for radiology imaging modalities and nuclear medicine by using a convolutional network to generate a standard-dose nuclear medicine image from low-dose nuclear medicine image, where the network includes N convolution neural network (CNN) stages, where each stage includes M convolution layers having K×K kernels, where the network further includes an encoder-decoder structure having symmetry concatenate connections between corresponding stages, downsampling using pooling and upsampling using bilinear interpolation between the stages, where the network extracts multi-scale and high-level features from the low-dose image to simulate a high-dose image, and adding concatenate connections to the low-dose image to preserve local information and resolution of the high-dose image, the high-dose image includes a dose reduction factor (DRF) equal to 1 of a radio tracer in a patient, the low-dose PET image includes a DRF of at least 4 of the radio tracer in the patient.
US11844630B2 Method and system to detect noise in cardiac arrhythmic patterns
Computer implemented methods and systems for detecting noise in cardiac activity are provided. The method and system obtain a far field cardiac activity (CA) data set that includes far field CA signals for a series of beats, overlay a segment of the CA signals with a noise search window, and identify turns in the segment of the CA signals. The method and system determine whether the turns exhibit a turn characteristic that exceed a turn characteristic threshold, declare the segment of the CA signals as a noise segment based on the determining operation, shift the noise search window to a next segment of the CA signal and repeat the identifying, determining and declaring operations; and modify the CA signals based on the declaring the noise segments.
US11844624B2 System and method for monitoring cerebral activity
A patient monitor for monitoring cerebral activity of a patient may include a processor configured to determine a depth of consciousness index for the patient based on electroencephalography (EEG) data and determine regional oxygen saturation for the patient based on regional oximetry data. Additionally, the processor may be configured to determine a metric associated with cerebral activity of the patient based at least in part on the one or more values of the depth of consciousness index and the one or more regional oxygen saturation values and to provide the one or more values of a depth of consciousness index and the metric to an output device.
US11844620B2 Configuring a cardiac monitoring device
A system for configuring an ambulatory medical device includes an ambulatory medical device configured to monitor at least one electrocardiogram signal received from a patient for an occurrence of one or more cardiac events. The system also includes a remote computing device configured to receive a set of threshold values related to operation of the ambulatory medical device. The threshold values identify one or more conditions indicative of an occurrence of one or more cardiac events. The remote computing device is configured to query a master lookup table to determine a lookup code associated with the received set of threshold values, establish a communication link with the ambulatory medical device, receive an activation notification indicating that the ambulatory medical device has been activated, and encode a key. The encoded key includes the lookup code. The remote computing device is configured to transmit the encoded key to the ambulatory medical device.
US11844619B2 Volumetric LAT map
A method includes assigning, to first voxels in a model of tissue of a chamber of a heart, respective first values of a parameter at respective locations on the tissue, the first voxels representing the locations, respectively. Some of the locations are on an endocardial surface of the tissue, and others of the locations are on an epicardial surface of the tissue. The method further includes assigning respective second values to second voxels in the model, a subset of which represent a portion of the tissue between the endocardial surface and the epicardial surface, by interpolating the first values. Other embodiments are also described.
US11844614B2 Analyzing and mapping ECG signals and determining ablation points to eliminate Brugada syndrome
A system and method for Brugada syndrome epicardial ablation comprising preparing an endocardial duration map; preparing a baseline epicardial duration map comprising at least one or more areas of delimination; and when some of the areas of delimination are greater than 200 ms, performing epicardial ablation of the areas of delimination greater than 200 ms. The method may further comprise preparing an updated epicardial duration map after performing epicardial ablation, and determining whether or not a BrS pattern appears in the updated epicardial duration map; and when the BrS pattern appears, performing epicardial ablation. The method may further comprise preparing an updated epicardial duration map after performing epicardial ablation, and determining whether or not an abnormal EGM exists in the updated epicardial duration map; and when the abnormal EGM exists, performing epicardial ablation. The method may further comprise preparing an updated epicardial map comprising maintaining anatomical volume data and adding electroanatomical data.
US11844613B2 Fatigue state determination device and fatigue state determination method
A fatigue state determination device and a fatigue state determination method determine a fatigue state of a subject. The fatigue state determination device includes a brain-function activation information provision unit and a fatigue state determination unit. The brain-function activation information provision unit provides brain-function activation information in order to activate a human brain function of a subject. The fatigue state determination unit determines a fatigue state of the subject based on facial-surface change information indicative of a time-series change of facial surface data on the subject while the brain-function activation information is being provided.
US11844612B2 Measurement averaging in a medical device
An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry measurements at a number of different tissue locations of a patient and average two or more of the oximetry measurements by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry measurements if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry measurements which are instantaneous measurement for patient tissue.
US11844610B2 System and method for monitoring gas exchange
The present disclosure pertains to a system and method for monitoring lung disease in a patient that is based on information that is derivable from home therapy devices including a ventilation therapy device and an oxygen saturation monitor such as a pulse oximeter. The measured parameters are used to model shunt fraction and a volume of dead space. Based on changes in gas exchange and results of a nitrogen washout test, a change in gas exchange impairment in the patient is observed and is then used to determine progression of a disease, identify a cause of the impairment, and/or to guide treatment of the patient.
US11844608B2 Posture analysis systems and methods
Example posture analysis systems and methods are described. In one implementation, a computing system identifies a deviation of a user's posture from a predetermined posture based on visual data associated with the user. The user is informed of the deviation via a graphical image displayed on a display device. The user is then provided with instructions for correcting the deviation via the graphical image displayed on the display device.
US11844607B2 Capnograph system further detecting spontaneous patient breaths
A capnograph system may be used together with a ventilation system for a patient. The capnograph system may include a capnography module with a carbon dioxide detector, which may generate a carbon dioxide signal responsive to an amount of carbon dioxide detected within an air path of the ventilation system. A monitoring circuit may further detect a pressure within the air path. A processing component within the capnography module may generate a pressure signal responsive to the pressure detected in the air path. The pressure signal, alone or in combination with other signals such as the carbon dioxide signal, may be used to detect spontaneous breaths of the patient.
US11844605B2 System, method and biomarkers for airway obstruction
Two biomarkers are provided for obstructive apnea. A first biomarker determines amplitude and timing of inspiratory efforts from a bioelectric signal. The respiratory rate is compared with a normal pre-detection rate, and the amplitude of the effort is compared with a normal amplitude. The obstructive apnea is likely present if a series of inspiratory efforts are above a normal amplitude and with increasing amplitude, but at a normal rate. A second biomarker determines heart rate and respiratory rate. A normal lower threshold for heartbeat interval is established, and if subthreshold events occur (short RR intervals), a commencement time for each sequence of subthreshold events is compared for a respiratory rate-normalized window. If the number of subthreshold events exceeds a minimum for the window, obstructive apnea is likely present.
US11844603B2 Visualizing a treatment of breast cancer
A method includes, in a medical procedure carried out during a time interval including at least first and second time periods, receiving, for the first time period, a first electrical signal indicative of at least a first position and a first orientation of a hand-held device directing energy to one or more volumetric portions of an organ. A second electrical signal indicative of at least a second position and a second orientation of the hand-held device is received for the second time period. Based on the first and second electrical signals, a cumulative energy applied to at least one of the one or more volumetric portions is estimated. The estimated cumulative energy, of at least one of the one or more volumetric portions, is overlaid on an anatomical image of the organ.
US11844596B2 Methods and systems for monitoring blood pressure in a person using radio waves
Methods and systems for monitoring blood pressure in a person are disclosed. A method for monitoring a blood pressure in a person involves transmitting millimeter range radio waves over a three-dimensional (3D) space below the skin surface of a person, receiving radio waves on multiple receive antennas, the received radio waves including a reflected portion of the transmitted radio waves that is reflected by blood in a blood vessel in the 3D space, isolating a signal that corresponds to the portion of the transmitted radio waves that is reflected by blood in the blood vessel in response to receiving the radio waves on the multiple receive antennas, and outputting a signal that corresponds to a blood pressure level in the person in response to the isolated signal.
US11844590B2 Necklace-shaped physiological monitor
The invention provides a neck-worn sensor (referred to herein as the ‘necklace’) that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the necklace can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.
US11844584B2 Robotic system for tele-surgery
Disclosed herein is a robotic tele-surgery system for performing laparoscopic surgeries. The system may include: a patient-side unit, a surgeon-side unit, and a controller that may be configured for establishing a master-slave relationship between the surgeon-side unit and the patient-side unit. The patient side unit may include a patient support assembly, at least two passive mounting mechanisms that may be slidably coupled to the patient support assembly and at least two slave robotic arms, coupled with a surgical instrument via a tool adapting mechanism from their distal end, and mounted on an associated passive support assembly from their base end. The surgeon-side unit may including at least two master robotic arms, and an ergonomic adjustment mechanism that may be configured for housing and adjusting the position and orientation of the master robotic arms.
US11844580B2 Control of a surgical instrument having backlash, friction, and compliance under external load in a surgical robotic system
For control of a surgical instrument in a surgical robotic system, multiple actuators establish a static pretension by actuating in opposition to each other in torque control. The static pretension reduces or removes the compliance and elasticity, reducing the backlash width. To drive the tool, the actuators are then moved in cooperation with each other in position mode control so that the movement maintains the static pretension while providing precise control.
US11844579B2 Adjustments based on airborne particle properties
A surgical system is disclosed. The surgical system can include a sensor configured to detect a property of airborne particles in a fluid within a patient's cavity. The surgical system can also include a surgical device and a control circuit configured to adjust a surgical function of the surgical device in response to an input signal indicative of the property of airborne particles in the fluid.
US11844576B2 Endograft visualization with optical shape sensing
A system for medical device deployment includes an optical shape sensing (OSS) system (104) associated with a deployable medical device (102) or a deployment instrument (107). The OSS system is configured to measure shape, position or orientation of the deployable medical device and/or deployment instrument. A registration module (128) is configured to register OSS data with imaging data to permit placement of the deployable medical device. An image processing module (142) is configured to create a visual representation (102′) of the deployable medical device and to jointly display the deployable medical device with the imaging data.
US11844575B1 Digital image analysis for robotic installation of surgical implants
Computer-implemented digital image analysis methods, apparatuses, and systems for robotic installation of surgical implants are disclosed. A disclosed apparatus plans a route within an anatomy of a patient from an incision site to a surgical implant site for robotic installation of a surgical implant. The apparatus uses digital imaging data to identify less-invasive installation paths and determine the dimensions of the surgical implant components being used. The apparatus segments the surgical implant into surgical implant subcomponents and modifies the surgical implant subcomponents, such that they can be inserted using the identified less-invasive installation paths.
US11844573B2 Active visual alignment stimuli in fundus photography
The technology described herein is directed to a fundus camera and, more specifically, to a fundus camera having a display that projects active visual alignment stimuli onto an eye of an examinee via one or more components of an optimal assembly. The active visual alignment stimuli are dynamically adjusted to guide an examinee toward optical alignment for fundus imaging.
US11844570B2 System and methods using real-time predictive virtual 3D eye finite element modeling for simulation of ocular structure biomechanics
Disclosed are systems, devices and methods for performing simulations using a multi-component Finite Element Model (FEM) of ocular structures involved in ocular accommodation.
US11844563B2 Energy-based surgical instruments incorporating cooling features
An ultrasonic surgical instrument includes an ultrasonic waveguide defining a blade at a distal end portion thereof. The ultrasonic waveguide is configured to transmit ultrasonic energy therealong to the blade. The blade defines a plurality of surfaces. At least one lumen is defined at least partially through the blade. The at least one lumen establishes a flow path through the blade extending from a first open end on one surface of the plurality of surfaces to a second open end on a different surface of the plurality of surfaces. The at least one lumen is configured to urge fluid through the blade along the flow path from the one surface to the different surface.
US11844560B2 Path planning device for multi-probe joint cryoablation
The disclosure relates to a path planning device for multi-probe joint cryoablation, the device comprising a memory and a processor. The memory stores a computer program, and the processor, when executing the computer program, implements the following steps: acquiring a target region in a medical scanned image of a target object and corresponding to a target tissue to be cryoablated; selecting a single-probe ablation region from the target region; for the single-probe ablation region, obtaining a puncture path of single-probe cryoablation and a corresponding ice ball coverage region; and if the ice ball coverage region does not completely cover target region, then taking the remaining region of the target region from which the ice ball coverage region is excluded as a new target region, and returning to the step of selecting the selecting the single-probe ablation region from the target region.
US11844559B2 Surgical method and apparatus for destruction and removal of intraperitoneal, visceral, and subcutaneous fat
The embodied invention is a method of removing intraperitoneal fat by using a freezing cryoprobe and inserting it into the abdominal cavity. The freezing cryoprobe is covered by a vacuum sleeve which provides for a method for abdominal fat removal once the cells are damaged. A multi-step surgical procedure is used to freeze, irrigate, and remove the destroyed fat tissue. Also, an ultrasonic transmitter is inserted into an outer cryoprobe sheath to assess organ position with the advantage of an internal transmitter which greatly aids in organ identification.
US11844554B1 Retrograde femoral nail system and related methods
Described herein are retrograde femoral nails and insertion systems suitable for stabilizing femoral fractures of the shaft and femur. After reaming the femoral canal, the intramedullary nail may be inserted with a retrograde approach through the knee. The nail includes four-start threaded holes in the distal region. The nail also includes oblique distal holes with a trajectory that targets the bone in the posterior condyles. The insertion instrumentation assembly and system includes an insertion handle with a retaining thread that prevents the connection bolt from falling out. An assembly shaft is also included, which assists the user in connecting the nail to the insertion handle. The system further includes an aiming guide with a retention mechanism that holds driver sleeves in place. The aiming guide also contains a hole to position a locking washer holder to interface with the nail.