Document Document Title
US11667764B2 Foam compositions and uses thereof
A variety of forms and form components are provided, including form components for articles of footwear and athletic equipment. The articles include a composition having a form structure, wherein the composition includes a thermoplastic copolyester elastomer comprising: (a) a plurality of first segments, each first segment derived from a dihydroxy-terminated polydiol; (b) a plurality of second segments, each second segment derived from a diol; and (c) a plurality of third segments, each third segment derived from an aromatic dicarboxylic acid. Methods of making the compositions and forms are provided, as well as methods of making an article of footwear including at least one of the form components. In some aspects, the forms and form components can be made by extrusion or injection molding to form the polymeric composition, or extrusion or injection molding to form the polymeric composition followed by compression molding of the form.
US11667763B2 Cellulose-fiber dispersion polyethylene resin composite material, formed body and pellet using same, production method therefor, and recycling method for cellulose-fiber adhesion polyethylene thin film piece
A cellulose fiber dispersion polyethylene resin composite material formed by dispersing a cellulose fiber into a polyethylene resin, in which a proportion of the above-described cellulose fiber is 1 part by mass or more and 70 parts by mass or less in a total content of 100 parts by mass of the polyethylene resin and the cellulose fiber, and the polyethylene resin satisfies a relationship: 1.7>half-width (Log(MH/ML))>1.0 in a molecular weight pattern obtained by gel permeation chromatography measurement, and a formed body and a pellet using the same, a production method therefor, and a recycling method for the cellulose fiber adhesion polyethylene thin film piece.
US11667762B2 UV-initiated reactions in polymeric materials
Methods of making crosslinked polymeric materials and crosslinked interlocked hybrid polymeric materials using photoinitiator, antioxidant, additive, and photoirradiation of polymeric blend and/or interlocked hybrid materials are provided. Methods of spatially controlling macroscopic properties and morphology of polymeric materials, and products made by the methods also are provided.
US11667759B2 Polyimide composite, a method of preparing thereof, and application thereof
A polyimide composite, a method of preparing thereof, and an application thereof are provided. A general structure of the polyimide composite is: SiO2-(β-CD-Ada)x/PI, and x is 3 to 5. The polyimide composite has the functions of self-repairing and anti-aging.
US11667755B2 Siloxane hybrid membranes for enhanced natural gas liquid recovery
This disclosure relates to functionalized polyhedral oligomeric silsesquioxanes (POSS) and polymeric membranes containing the functionalized POSS. This disclosure also relates to methods of using the membranes for natural gas liquid recovery, such as removal and recovery of C3+ hydrocarbons from natural gas.
US11667754B2 Tetracarboxylic dianhydride, carbonyl compound, polyimide precursor resin, and polyimide
A tetracarboxylic dianhydride includes: at least one acid dianhydride (A) selected from the group consisting of compounds each having an endo/exo type three-dimensional structure represented by a particular general formula and their enantiomeric compounds each having an exo/endo type three-dimensional structure; and/or an acid dianhydride (B) having an endo/endo type three-dimensional structure represented by a particular general formula, wherein a content of the acid dianhydride (B) in a total amount of the acid dianhydrides (A) and (B) is 30 to 100% by mole in a mole ratio.
US11667753B2 Multimodal polyalkylene terephthalate
A method of forming a multimodal Polyalkylene Terephthalate (PAT) can include: providing a feed of a low molecular weight (LMW) PAT, the LMW PAT having a low average molecular weight; providing a feed of high molecular weight (HMW) PAT, the HMW PAT having a high average molecular weight, wherein the low average molecular weight is lower than the high average molecular weight; mixing the feed of LMW PAT with the feed of HMW PAT in a mixer to form a multimodal PAT; and providing the multimodal PAT as output. The multimodal PAT can include: a low average molecular weight of a low molecular weight (LMW) PAT; and a high average molecular weight of a high molecular weight (HMW) PAT mixed with the LMW PAT to form the multimodal PAT, wherein the multimodal PAT is devoid of talc.
US11667752B2 Copolyester including cyclic aliphatic unit, method of preparing the same, and optical film with low water absorption and low birefringence including the same
The present disclosure relates to a copolyester including a polymer formed by polymerization of monomers represented by the following Structural Formula 1 to Structural Formula 4: (in the above Structural Formula 1 to Structural Formula 4, R1 to R18 are identical to or different from each other and are each independently selected from the group consisting of H, substituted or unsubstituted linear or branched C1-C20 alkyl and substituted or unsubstituted C6-C20 aryl).
US11667747B2 Binders containing secondary amine groups, based on cyclic ethers
The present invention relates to a process for producing polyaspartic ester compositions by reacting cyclic ethers bearing primary amino and/or primary aminoalkyl groups with fumaric and/or maleic esters, to the polyaspartic ester compositions thus obtainable, and to the use thereof in two-component coating compositions.
US11667745B2 Method for producing oxymethylene copolymer
The present invention addresses the problem of providing a method for producing an oxymethylene copolymer, which is capable of producing an oxymethylene copolymer having a high molecular weight with high yield and high economic efficiency. This problem is able to be solved by a method for producing an oxymethylene copolymer, in which a copolymer starting material containing a trioxane and a comonomer is subjected to a polymerization reaction in the presence of a polymerization initiator that contains an acidic compound (A), and wherein: the copolymer starting material contains a basic compound (B); an acidic compound (C) that is different from the acidic compound (A) is added into the copolymer starting material before performing the polymerization reaction, thereby causing a reaction between the basic compound (B) and the acidic compound (C) in advance; and the polymerization reaction is carried out by means of melt polymerization.
US11667739B2 Making particles with radial variation
Provided is a process of making polymeric beads comprising (a) providing a suspension of monomer droplets in an aqueous medium at pH of 7 or less, wherein the monomer droplets comprise one or more monofunctional vinyl monomers, one or more multifunctional vinyl monomers, and one or more initiators, wherein the aqueous medium comprises one or more derivatives of a nitrite salt in an amount, by weight based on the weight of the aqueous medium, of 0.005% to 0.5%, (b) initiating polymerization of the monomer, wherein no pH-raising substance is added after beginning step (b) until 60% or more by weight of all monofunctional monomer has been converted to polymer.
US11667732B2 Reactive carbonate for elastomeric articles
The disclosure describes the preparation and use of reactive carbonates containing a metal carbonate bound to a reactive compound, wherein the reactive compound comprises a mineral binding group and a polymer reactive group connected together by a linking group. Such reactive carbonates are useful as reagents in processes for making mineral-bound elastomeric materials, and in methods for reducing cavitation in elastomer materials.
US11667731B2 Stabilized UV active organopalladium compounds as vinyl addition catalysts
Embodiments in accordance with the present invention encompass compositions comprising a long shelf stabilized organopalladium compound of formula (I) as described herein. The composition further contains a photoacid generator, a photosensitizer and one or more olefinic monomers as described herein. The shelf life of the compositions can further be extended by employing a stabilizer, such as for example, a hindered amine. The composition undergoes vinyl addition polymerization when it is exposed to a suitable actinic radiation to form a substantially transparent film or a three dimensional object. More specifically, the compositions of this invention are stable at room temperature for several days to several months and can also be stored at higher temperatures from about 40° C. to 60° C. for several days and undergo mass polymerization only when subjected to suitable actinic radiation. The monomers employed therein have a range of optical and mechanical properties, and thus these compositions can be tailored to form films and/or three dimensional objects having various opto-electronic properties. Accordingly, compositions of this invention are useful in various applications, including as coatings, encapsulants, fillers, leveling agents, sealants, adhesives, among others.
US11667728B1 Reactor and processes for endothermic reactions at high temperatures
An endothermic catalytic reactor apparatus that includes a radiant furnace that includes a burner adapted to provide thermal energy to the furnace, a reactor that includes an entrance portion and an exit portion and is situated within the furnace and adapted to receive radiant thermal energy. The reactor includes one or more static helical spirals defining a flow path within the reactor that travels from the entrance portion to the exit portion. The helical spirals are adapted to hold a catalyst on an outer surface thereof. Incoming port(s) are located on the entrance portion and are adapted to receive reactive starting materials. An exit port is located near the exit portion and is adapted to expel product from the reactor. The reactor is adapted to allow starting materials to receive radiant thermal energy and interact with catalyst sufficiently to cause a reaction to occur that converts starting materials to product.
US11667727B2 Carboxyalkyl chitosan
The present invention relates to a carboxyalkyl chitosan, compositions comprising same, a process for manufacturing same, and various applications thereof, in particular in the field of therapy, rheumatology, ophthalmology, esthetic medicine, plastic surgery, internal surgery, dermatology or cosmetics.
US11667726B2 Methods and compositions relating to bispecific anti-CHI3L1 antibody reagents for the treatment of cancer
It is demonstrated herein that inhibitors of immune checkpoints and CHI3L1 are synergistic. Accordingly, described herein are methods and compositions relating to combinatorial therapies for cancer, e.g., comprising an inhibitor of CHI3L1; and an inhibitor of an immune checkpoint protein. In some embodiments, the CHI3L1 inhibitor can be an antibody or antibody reagent as described herein.
US11667723B2 Lymphocytes-antigen presenting cells co-stimulators and uses thereof
Disclosed herein are fusion proteins having a first domain that activates an antigen-presenting cell (APC) (e.g., a dendritic cell) by binding to an activation receptor of the APC, and a second domain that activates an immune effector cell (e.g., a T cell) by targeting a co-stimulatory signaling pathway of the immune effector cell, as well as polynucleotides that encode such fusion proteins. Disclosed herein are also genetically engineered immune effector cells expressing such fusion protein, methods of their production, and their uses in treatment of diseases such as cancers.
US11667721B2 CD30 bispecific antibodies and method of immunotherapy of CD30+ malignancies
The present invention provides novel bispecific antibodies that bind to human CD30 and uses thereof. Methods of treating cancer using the bispecific antibodies described herein are also provided.
US11667711B2 Anti-human LAG-3 antibodies and their use in immunohistochemistry (IHC)
Provided are chimeric or recombinant antibodies (Ab), or antigen binding fragments thereof, or monomeric or dimeric antigen binding proteins, that can specifically bind to human LAG-3 polypeptides, including human LAG-3 polypeptides expressed on the surface of lymphocytes such as activated T cells that have infiltrated tumors or tumor infiltrating lymphocytes (TILs), and methods for making and using them. In alternative embodiments, chimeric or a recombinant antibodies (Ab), or antigen binding fragments thereof, or monomeric or dimeric antigen binding proteins as provided herein are used for in vitro diagnostics, for example, in immuno-histochemistry (IHC), for example, to diagnose and/or treat a cancer, for example, bladder cancer, urothelial carcinoma, breast cancer, lung cancer, Non-Small Cell Lung Cancer, renal carcinoma, Renal Clear cell Carcinoma and/or melanoma or malignant melanoma, by their ability to specifically bind to activated T cells that have infiltrated tumors, or tumor infiltrating lymphocytes.
US11667710B2 Anti-Siglec-9 antibodies and methods of use thereof
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a Siglec-9 protein, e.g., human Siglec-9 or a mammalian Siglec-9, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
US11667707B2 SPNS2 neutralizing antibody
The purpose of the present invention is to provide an antibody that can be expected to have a therapeutic effect in autoimmune diseases and anticancer treatment by inhibiting S1P transport by SPNS2 to thereby inhibit lymphocyte migration. The present invention is an SPNS2 neutralizing antibody or a fragment thereof, or a derivative thereof, that specifically binds to vertebrate SPNS2 and has lymphocyte migration inhibitory activity through SW transport inhibition.
US11667705B2 IL-17A binding proteins
Binding molecules to IL-17A. The binding molecules are useful in the treatment of disorders, for example psoriasis.
US11667699B2 Anti-MS4A4A antibodies and methods of use thereof
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
US11667695B2 Antibodies and processes for preparing the same
Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.
US11667693B2 Synthetic biology-based ADCC technology
A novel synthetic biology-based ADCC technology is provided that enhances or enables ADCC response. The novel ADCC technology can be used to prevent or treat cancers, infectious, inflammatory or autoimmune diseases, and other diseases where elimination of diseased cells is desirable.
US11667687B2 Masked activatable interferon constructs
Provided herein are activatable cytokine constructs that include: (a) a first monomer construct comprising a first peptide mask (PM1), a third cleavable moiety (CM3), a first mature cytokine protein (CP1), a first cleavable moiety (CM1), and a first dimerization domain (DD1), wherein the CM1 is positioned between the CP1 and the DD1, and the CM3 is positioned between the PM1 and CP1; and (b) a second monomer construct comprising a second mature cytokine protein (CP2), a second cleavable moiety (CM2), and a second dimerization domain (DD2), where the CM2 is positioned between the CP2 and the DD2, where: the DD1 and the DD2 bind each other; and where the ACC is characterized by a reduction in at least one activity of the CP1 and/or CP2 as compared to a control level of the at least one activity of the CP1 and/or CP2.
US11667683B2 Articles comprising a silk polypeptide for antigen delivery
The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
US11667682B2 Split intein mediated protein polymerization for microbial production of materials
The present disclosure is directed to systems and methods for synthesizing a spidroin. In some embodiments, the methods comprise synthesizing a monomer in vivo in a heterologous host, the monomer comprising an N-terminus IntC domain and a C-terminus IntN domain, and post-translationally polymerizing the synthesized monomer via in vitro split-intein mediated polymerization.
US11667681B2 Green alga bicarbonate transporter and uses thereof
Provided herein are green alga Cia8 polypeptides and the polynucleotides that encode them. Also provided herein are transformed cells and transgenic plants that include one or more of the polynucleotides and/or polypeptides provided herein.
US11667677B2 Inducible, tunable, and multiplex human gene regulation using CRISPR-Cpf1
Drug-inducible, tunable, and multiplexable Clustered Regularly Interspaced Short Palindromic Repeats from Prevotella and Francisella 1 (Cpf1)-based activators, and methods of use thereof.
US11667675B2 MASP inhibitory compounds and uses thereof
The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.
US11667674B2 Antibacterial cyclic lipopeptides
Cyclic lipopeptides having one or more modifications relative to daptomycin, and methods of making them are provided. The cyclic lipopeptides can be used as antibacterial agents. The daptomycin analogues are generated by chemical synthesis, which makes introduction of an unnatural amino acid and any modification into daptomycin possible. Pharmaceutical compositions and method of use thereof for the disclosed daptomycin analogues are also provided.
US11667673B2 Therapeutically active compounds and their methods of use
Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
US11667670B2 Corn protein retention during extraction
Described herein is a method of maintaining corn protein yield during extraction, comprising obtaining a corn gluten material, washing the corn gluten material to remove non-protein components with an ethanol-water solvent comprising at least 85 wt % ethanol to obtain a corn protein concentrate product, wherein the loss of corn protein content during extraction is less than 25% of total corn protein.
US11667669B2 Epoxy-(meth)acrylate monomers and polymers and methods of making and using the same
The present invention relates to the unexpected discovery of novel monomer compounds capable of crosslinking interpenetrating polymer networks (IPNs). In certain embodiments, the monomer compounds of the invention each comprise at least one methacrylate functionality capable of forming polymeric bonds with other methacrylate and vinyl functionalities, and at least one epoxide functionality capable of forming polymeric bonds with epoxide functionalities, amine functionalities, and/or reactive oxygen species.
US11667666B2 Methods and compositions for treatment of cancer
In an aspect, the disclosure pertains to inhibitors of ANGPTL4; synthesis methods for making disclosed compounds; pharmaceutical compositions comprising disclosed compounds; methods of treating disorders of uncontrolled cellular proliferation, e.g., a cancer; and methods of treating a disease associated with an ANGPTL4 dysfunction using disclosed compounds and pharmaceutical compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
US11667664B2 Cyclic dinucleotides for cytokine induction
A cyclic dinucleotide compound of Formula (I): wherein X1 is H or F; X2 is H or F; at least one among X1 and X2 is a fluorine atom; Z is OH, OR1, SH or SR1, wherein: R1 is Na or NH4, or R1 is an enzyme-labile group which provides OH or SH in vivo such as pivaloyloxymethyl; B1 and B2 are bases chosen from Adenine, Hypoxanthine or Guanine, and B1 is a different base than B2 and a pharmaceutically acceptable salt thereof. Pharmaceutical compositions including the cyclic dinucleotide, as well as their use in the treatment of a bacterial infection, a viral infection or a cancer are also described.
US11667662B2 Modulators of 5′-nucleotidase, ecto and the use thereof
Compounds that modulate the conversion of AMP to adenosine by 5′-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5′-nucleotidase, ecto is also provided.
US11667658B2 Chemical synthesis of the organoarsenical antibiotic arsinothricin
The subject invention provides methods for the chemical synthesis of racemic arsinothricin (D,L-AST), the novel organoarsenical antibiotic. One is by condensation of the 2-chloroethyl(methyl)arsinic acid with acetamidomalonate, and the second involves reduction of the N-acetyl-protected derivative of hydroxyarsinothricin (AST-OH) and subsequent methylation of the resulting sodium salt of trivalent arsenic intermediate with methyl iodide. The enzyme AST N-acetyltransferase (ArsN1) was utilized to purify L-AST from racemic AST. This expedient chemical synthesis of AST provides a source of this novel antibiotic for future drug development.
US11667656B2 Crystalline forms of Tenofovir alafenamide
The present invention provides novel crystalline forms of tenofovir alafenamide comprising tenofovir alafenamide and two different pharmaceutically acceptable acids, compositions and processes for the preparation thereof, and their use in the treatment of a human immunodeficiency virus (HIV) infection or a hepatitis B virus (HBV) infection.
US11667649B2 Heteroaromatic macrocyclic ether chemotherapeutic agents
Disclosed are heterocyclic heteroaromatic macrocyclic ether compounds, pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. Also disclosed are methods of treating or preventing cancer using the heterocyclic heteroaromatic macrocyclic ether compounds, pharmaceutically acceptable salts of the compounds, and pharmaceutical compositions thereof.
US11667636B2 Modulators of Mas-related G-protein receptor X2 and related products and methods
Methods are provided for modulating MRGPRX2 generally, or for treating a MRGPRX2 dependent condition more specifically, by contacting the MRGPRX2 or administering to a subject in need thereof, respectively, an effective amount of a compound having structure (I): or a pharmaceutically acceptable salt, isomer, hydrate, solvate or isotope thereof, wherein A, B, C, D, E, G, W, Y, Z, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Pharmaceutical compositions containing such compounds, as well as the compounds themselves, are also provided.
US11667634B2 Inhibitors of RAF kinases
Provided herein are heteroaryl inhibitors of receptor tyrosine kinase effector (RAF), pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of disease.
US11667632B2 2-(1H-indazol-3-yl)-3H-imidazo[4,5-C]pyridines and their anti-inflammatory uses thereof
Indazole compounds for treating various diseases and pathologies are provided. More particularly, the use of an indazole compound or analogs thereof, in the treatment of inflammatory diseases or disorders is provided.
US11667630B2 Nitrogen-containing 6-membered cyclic compound
A novel compound represented by the following general formula (1), or a salt thereof, which has a superior EP4 receptor agonist activity, and a medicament containing the compound or a salt thereof as an active ingredient, which can be used for promotion of osteogenesis, therapeutic treatment and/or promotion of healing of fracture and the like.
US11667627B2 Salt and crystal forms of PLK-4 inhibitor
A fumarate salt and a maleate salt of compound (I) represented by the following structural formula, as well as their corresponding pharmaceutical compositions, are disclosed. Particular single crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are also disclosed. The present invention also provides methods of treating a subject with a cancer.
US11667626B2 Compound and organic light-emitting device comprising same
Provided is a compound of Formula 1: and an organic light emitting device including the same.
US11667619B2 Synthesis and purification of cannabinol from cannabidiol
A method to prepare cannabinol (CBN) from derived cannabidiol (CBD) is disclosed. The CBD can be derived from hemp and reacted with a halogen, leading to the cyclization and aromatization of CBD to CBN. The removal of halogen is improved via selective solvent exchange. CBN is isolated from the reaction mixture by use of orthogonal chromatography techniques to provide CBN of high purity.
US11667618B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same
The present disclosure provides an azulene ring-containing compound, its use, and an organic photoelectric device including the same. The azulene ring-containing compound is a compound comprising a structure of Formula I. The organic photoelectric device includes an anode, a cathode, and one or more organic thin film layers located between the anode and the cathode; and at least one of the organic thin film layers contains the above-mentioned azulene ring-containing compound comprising the structure of Formula I. The azulene ring-containing compound provided by the present disclosure has an energy level difference ΔEst≤0.3 eV between the lowest singlet state S1 and the lowest triplet state T1, and has a light-emitting mechanism of a thermally activated delayed fluorescent material, and can be used as a thermally activated delayed fluorescent material for organic photoelectric device, so that the light-emitting efficiency of the device is improved.
US11667615B2 Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors
The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
US11667614B2 Process for the preparation of highly pure Salcaprozic Acid and pharmaceutically acceptable salts thereof
Processes that use novel reagents for the removal of colored impurity during the preparation of Salcaprozic Acid and pharmaceutically acceptable salts thereof. The processes include hydrolysis of 8-(2,4-dioxo-1,3-benzoxazin-3-yl)octanoic acid ethyl ester in the presence of or by contacting it with benzotriazole, hydrazine and/or sodium borohydride.
US11667606B2 Thyromimetics
Compounds are provided having the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein A, X1, X2, Q, R1, R2 and n are as defined herein. Such compounds function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their use and preparation.
US11667602B2 Compounds and their use
The specification generally relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof, where A, U, V, W, X, Y, Z, R1, R2, R3, R4 and R5 have the meanings defined herein. Such compounds are modulators of RXFP1 and may be useful as therapeutic agents. The specification also relates to the use of such compounds to treat or prevent diseases and conditions including heart failure, heart failure with preserved ejection fraction, heart failure with mid-range ejection fraction, heart failure with reduced ejection fraction, chronic kidney disease and acute kidney injury. The specification further relates to compositions comprising such compounds, intermediates useful in processes for preparing such compounds, and processes for preparing such compounds using such intermediates.
US11667601B2 Calcium BOPTA complex
The present invention relates to the calcium complex of (4RS)(4-carboxy-5,8,11-tris(carboxymethyl)-1-phenyl oxa-5,8,11-triazatridecan-13-oato(5-))pentahydrogen (BOPTA) in the form of a salt, to the process for its preparation and to a formulation comprising said salt.
US11667596B2 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione for suppressing and treating alpha-synucleinopathies, tauopathies, and other disorders
Disclosed herein are methods of treating or suppressing a disorder selected from the group consisting of α-synucleinopathies, tauopathies, ALS, traumatic brain injury, and ischemic-reperfusion related injuries.ury, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of the formula: or the hydroquinone form thereof; or a solvate or hydrate thereof.
US11667593B2 Compounds, including nonsymmetrical polyaromatic hydrocarbons, and methods
Methods of forming arenes, including asymmetrical arenes, such as asymmetrical pyrene derivatives. Substituents of starting materials may be selected to direct a photochemical cascade and possibly a 1,2-aryl shift. The methods may include a Mallory cyclization, which is controlled, at least in part, by substituents of the starting materials. Compounds and compositions including asymmetrical arenes.
US11667592B2 Methods and apparatus for performing chemical and electrochemical reactions
Apparatuses and methods for performing coupled chemical and electrochemical reactions are disclosed. An electrochemical cell has a first reaction chamber configured to perform a chemical reaction and an anode chamber configured to perform an electrochemical reaction. The first reaction chamber and the anode chamber are separated by a first membrane. The first membrane acts as a cathode of the cell, a hydrogen-selective layer and a catalyst. The first membrane may comprise a layer of palladium or a palladium alloy. An ion exchange membrane separates the first membrane and the anode chamber. The chemical and electrochemical reactions may respectively be hydrogenation and dehydrogenation reactions.
US11667589B2 Composting device with trim bezel
The disclosure relates to a composting device including a housing defining an interior, and having a top wall defining an access opening providing access to the interior, a door moveable relative to the access opening between open/closed positions to selectively open/close the access opening, a trim bezel with a trim bezel opening, and a bin located within the interior and having a fill opening in communication with the trim bezel opening.
US11667588B2 Stabilized liquid ammonia fertilizer from animal waste
A liquid fertilizer is produced from off-gassed ammonia resulting from the processing of animal waste materials, particular animal manure. The vaporized ammonia is generated primarily by heating the animal waste materials and capturing the resulting vapors and particulate materials. The ammonia vapors and particles are removed from the gas stream through a scrubbing operation, which creates an ammonium-enriched liquid stream that can be concentrated into an organic fertilizer having a high-nitrogen content.
US11667585B2 Ceramic substrate with glass fill for decoration and housing materials
A ceramic composite article includes a substrate including a matrix of ceramic material defining a network of interstitial regions and a transparent material occupying at least some of the interstitial regions of the substrate. The transparent material can have a melting point lower than a melting point of the ceramic material. The matrix of ceramic material can be formed by a 3D printing process.
US11667584B2 Compositions for erosion and molten dust resistant environmental barrier coatings
Compounds are generally provided, which may be particularly used to form a layer in a coating system. In one embodiment, the compound may have the formula: AxBbLn1-x-bHf1-t-dTitDdMO6, where: A is Al, Ga, In, Sc, Y, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Fe, Cr, Co, Mn, Bi, or a mixture thereof; x is about 0.01 to about 0.99; b is 0 to about 0.5, with 1-x-b being 0 to about 0.99 such that Ln is present in the compound; Ln is a rare earth or a mixture thereof that is different than A; t is 0 to about 0.99; D is Zr, Ce, Ge, Si, or a mixture thereof; d is 0 to about 0.5; the sum of t and d is less than 1 such that Hf is present in the compound; and M is Ta, Nb, or a mixture thereof.
US11667582B2 Method for infiltrating a ceramic, artificial or natural stone surface
The object of the invention is a method for infiltrating a ceramic, artificial or natural stone surface, wherein a material forming a bond with valences on the surface is applied and mechanically rubbed onto the surface, whereby frictional heat is generated, wherein the material is used as a solution or suspension, and which comprises applying a hydrophobizing infiltration composition onto the surface to be coated, followed by rubbing it in until a homogeneous distribution and filling of the pores in the surface is achieved for improving the surface properties.
US11667579B2 Polycrystalline chalcogenide ceramic material
The invention relates to a polycrystalline IR transparent material produced by sintering chalcogenide powder, e.g., ZnS powder, using hot uniaxial pressing followed by hot isostatic pressing. The microstructure of the material described in this disclosure is much finer than that found in material produced using the state of the art process. By using a powder with a particle size fine enough to improve sintering behavior but coarse enough to prevent a lowering of the wurtzite-sphalerite transition temperature, a highly transparent material with improved strength is created without degrading the optical properties. A high degree of transparency is achieved during hot pressing by applying pressure after the part has reached a desired temperature. This allows some degree of plastic deformation and prevents rapid grain growth which can entrap porosity. The crystallographic twins created during this process further inhibit grain growth during hot isostatic pressing.
US11667577B2 Y2O3—ZrO2 erosion resistant material for chamber components in plasma environments
A method of manufacturing a chamber component for a processing chamber comprises forming a green body using a Y2O3—ZrO2 powder consisting essentially of 55-65 mol % Y2O3 and 35-45 mol % ZrO2; and sintering the green body to produce a sintered ceramic body consisting essentially of one or more phase of Y2O3—ZrO2, the sintered ceramic body consisting essentially of 55-65 mol % Y2O3 and 35-45 mol % ZrO2.
US11667573B2 Compositions and method to improve the strength development of calcium silicate-based cements and concretes
Calcium silicate-based cements and concretes are disclosed, which result in concrete compositions that have an improved strength development. A cement product includes a plurality of particles of a carbonatable calcium silicate cement and a first additive; wherein, the first additive is an organic molecule with at least one primary, secondary or tertiary amine group.
US11667567B2 Compositions, methods, and systems to form vaterite with magnesium oxide
Provided herein are compositions, methods, and systems comprising vaterite and magnesium oxide.
US11667559B2 Method for manufacturing optical fiber parent material, and method for manufacturing optical fiber
A method for manufacturing an optical fiber preform including a core part and a cladding part is disclosed. The method includes: adding an alkali metal to an inner surface of a silica-based glass pipe; etching the inner surface of the silica-based glass pipe to which the alkali metal is added; making a glass rod by collapsing the silica-based glass pipe after the etching; and making an optical fiber preform using the glass rod. The silica-based glass pipe is heated in the adding such that a surface temperature of the silica-based glass pipe falls within a temperature range of 1500° C. or higher to lower than 2000° C.
US11667557B2 Apparatus and method for producing porous glass preform
A method and an apparatus for producing a porous glass preform by using organosiloxane raw material is provided. The apparatus for producing the porous glass preform 12 according to the present embodiment is configured to mix organosiloxane in a liquid state being a raw material with a carrier gas in a vaporizer 6, heat this mixture to be vaporized, supply this vapor to a burner 13 as a gas raw material, and produce a porous glass preform by depositing a glass fine particle produced by combusting the gas raw material on a starting material, herein the apparatus for producing a porous glass preform includes a moisture removing apparatus 8 configured to remove moisture in the carrier gas and supply the vaporizer with the carrier gas.
US11667554B2 Wastewater treatment apparatus and process therefor
Wastewater treatment plants and processes for treating wastewater are described. The wastewater treatment plant utilizes channel plug flow dynamics with attached growth media and pure oxygen or mixtures of pure oxygen and compressed air.
US11667553B2 Method and system for the treatment of cyanide-containing fluids
A method and system for treating cyanide-containing fluids, in particular cyanide-containing waste water, wherein cyanide-containing fluid is subject to a pretreatment in a pretreatment zone, in which at least one predetermined pH value and a predetermined temperature is set, wherein a base fluid is formed with the pretreatment. Base fluid is reacted at least with an oxidation means in at least one reaction reactor, whereby an oxidation reaction of the cyanide is initiated. Fluid from the reaction reactor is transferred as intermediate fluid into at least one process reactor, in which conditions exist in which the oxidation reaction of the cyanide initiated in the reaction reactor can take place, wherein a process fluid is formed. A continuous flow of fluid is maintained at least periodically, wherein the base fluid is transferred continuously from the pretreatment zone into the reaction reactor, intermediate fluid is transferred continuously from the reaction reactor into the process reactor, and process fluid is removed continuously from the process reactor.
US11667546B1 Drop-in treatment apparatus and system for PFAS-impacted liquids
A drop-in treatment apparatus and system for PFAS-impacted liquids. The drop-in treatment apparatus and system may comprise one or more cartridges having a plurality openings; one or more mesh containers disposed within the one or more cartridges; one or more tethers; a submersible pump coupled to the cartridges via the tethers; and a power source electrically coupled to the submersible pump. The drop-in treatment apparatus may further comprise a plurality of prescribed masses of sorbent or resin filled within the mesh containers, such that the prescribed masses of sorbent or resin are disposed within the cartridges. The prescribed masses of sorbent or resin may be configured to remove PFAS compounds from a liquid and may be in the range of 0.1-50,000 milligrams per milliliter of liquid volume to be treated. The sorbent may be pyrogenic carbon, granular activated carbon, biochar, zeolite, aluminosilicates, and combinations thereof.
US11667532B2 Method for producing silicon carbide from waste circuit board cracking residue
The invention discloses a method for producing silicon carbide from waste circuit board cracking residue, belongs to the field of comprehensive utilization of waste circuit board cracking products, and particularly relates to a method for high-valued utilization of non-metal components in waste circuit board cracking residue. The method mainly comprises the following steps: rolling and crushing, vibration sorting, ultrafine pulverization and electro-separation, quantitative batching, microwave sintering and discharging and grading. Compared with the prior art, rolling crushing is adopted to replace traditional shearing crushing, microwave sintering is adopted to replace a traditional Acheson smelting furnace, the effects of being easy to operate, saving energy and reducing consumption are achieved, the production efficiency is greatly improved, and the production cost is reduced. A brand-new method for obtaining high-purity silicon carbide by partially replacing anthracite and quartz sand with cracked coke and silicon dioxide in waste circuit board light plates or epoxy resin cracking residues is adopted, and high-value utilization of waste resources is achieved. The method has the characteristics of simple and feasible process, low manufacturing cost and wide adaptability, and is beneficial to improving the economic benefit and social benefit of enterprise production.
US11667531B2 Thermal interface material, method for thermally coupling with thermal interface material, and method for preparing thermal interface material
A thermal interface material for transferring heat by interposing between two materials may include a graphite film. The graphite film may have a thickness of 1 μm to 50 μm, a density of 1.40 g/cm3 to 2.26 g/cm3, a thermal conductivity of 500 W/mK to 2000 W/mK in a film plane direction, and an arithmetic average roughness Ra of 0.1 μm to 10 μm on a surface of the graphite film.
US11667530B1 Method for preparing heteroatom-doped CNHs and heteroatom-doped carbon nanohorns supporting platinum, and catalyst
A method includes the following steps: a first step: the material containing heteroatom and graphite powder are mixed for a preset time by grinding, and the molar ratio of heteroatom to carbon atom is 1%-10%, then the heteroatom precursors are obtained; a second contact step: the heteroatom precursor is filled into a graphite rod with holes and compacted, then the graphite rod is dried for a preset time to obtain a plasma anode and using a DC arc plasma device to prepare the graphite anode into heteroatom-doped CNHs; a third contact step: the heteroatom-doped CNHs are dispersed in a reducing solution, a platinum salt is added to stir evenly, the reduction reaction is carried out by heating and stirring, and after centrifugation, washing and drying, a catalyst with platinum loading is obtained.
US11667528B2 Method for removing cadmium in the manufacture of phosphoric acid
Methods for removing cadmium (Cd) from a phosphoric acid solution produced in a wet process for manufacturing phosphoric acid, comprising treating the wet-process phosphoric acid solution with a small amount of a solid adsorbing material and a complex reagent to form a cadmium complex-contaminated solid adsorbing material, and removing the contaminated solid adsorbing material to yield a treated phosphoric acid solution having a low Cd content.
US11667526B2 Process and plant for producing a synthesis gas product stream having an adjustable H2/CO ratio and a pure hydrogen stream
Proposed are a process and a plant for producing a synthesis gas product stream having an adjustable H2/CO ratio and a pure hydrogen stream, wherein it is provided according to the invention that a substream of a deacidified synthesis gas stream is supplied to a membrane separation plant fitted with a hydrogen-selective membrane and the remaining substream is supplied to a pressure swing adsorption plant, wherein the latter affords a pure hydrogen stream and a fuel gas stream. The hydrogen-enriched permeate stream obtained from the membrane separation is likewise supplied to the pressure swing adsorption plant, thus enhancing the yield of pure hydrogen. The hydrogen-depleted retentate stream obtained from the membrane separation is discharged as a synthesis gas product stream and if of a suitable composition may be utilized as oxo gas.
US11667522B2 MEMS package comprising multi-depth trenches
The present disclosure relates to a MEMS package having different trench depths, and a method of fabricating the MEMS package. In some embodiments, a cap substrate is bonded to a device substrate. The cap substrate comprises a cap substrate bonded to a device substrate. The cap substrate comprises a MEMS trench, a scribe trench, and an edge trench respectively recessed from at a front-side surface of the cap substrate. A stopper is disposed within the MEMS trench and raised from a bottom surface of the MEMS trench.
US11667521B2 Method of constructing a micromechanical device
A method of constructing a micromechanical device by additive manufacturing for characterizing strength of a low dimensional material sample, the method including: a) deriving a three-dimensional representation arranged to represent a said micromechanical device with reference to at least one physical characteristic of a said low dimensional material sample; b) transforming the three-dimensional representation into a plurality of two-dimensional representations arranged to individually represent a portion of the three-dimensional representation; and c) forming the micromechanical device from a fluid medium arranged to transform its physical state by stereolithography apparatus in response to a manipulated illumination exposed thereto, whereby a said low dimensional material sample is loaded onto the formed micromechanical device.
US11667520B2 Manufacturing method for a micromechanical component, a corresponding micromechanical component and a corresponding configuration
A manufacturing method for a micromechanical component. The method includes: providing an ASIC component including first front and rear sides, a strip conductor unit being provided at the first front side; providing a MEMS component including second front and rear sides, a micromechanical functional element situated in a cavity at the second front side; bonding the first front side onto the second front side; back-thinning the first rear side; forming vias starting from the back-thinned first rear side and from a redistribution unit on the first rear side, the vias electrically connecting the strip conductor unit to the redistribution unit; forming electrical contact elements on the redistribution unit; and back-thinning the second rear side. The back-thinning of the first and second rear side taking place so that a thickness of the stack made up of ASIC component and MEMS component is less than 300 micrometers.
US11667519B2 Semiconductor device including a microelectromechanical structure and an associated integrated electronic circuit
An integrated semiconductor device includes: a MEMS structure; an ASIC electronic circuit; and conductive interconnection structures electrically coupling the MEMS structure to the ASIC electronic circuit. The MEMS structure and the ASIC electronic circuit are integrated starting from a same substrate including semiconductor material; wherein the MEMS structure is formed at a first surface of the substrate, and the ASIC electronic circuit is formed at a second surface of the substrate, vertically opposite to the first surface in a direction transverse to a horizontal plane of extension of the first surface and of the second surface.
US11667518B2 MEMS packaging structure and manufacturing method therefor
A micro-electro-mechanical system (MEMS) package structure and a method for fabricating the MEMS package structure. The MEMS package structure includes a MEMS die (200) and a device wafer (100). A control unit and an interconnection structure (300) are formed in the device wafer (100), and a first contact pad (410) and an input-output connecting member (420) are formed on a first bonding surface (100a) of the device wafer (100). The MEMS die (200) is coupled to the first bonding surface (100a) through a bonding layer (500). The MEMS die (200) includes a closed micro-cavity (220) and a second contact pad (220). The first contact pad (410) is electrically connected to a corresponding second contact pad (220). An opening (510) that exposes the input-output connecting member (420) is formed in the bonding layer (500). The MEMS package structure allows electrical interconnection between the MEMS die (200) and the device wafer (100) with a reduced package size, compared to those produced by existing integration techniques. In addition, function integration ability of the package structure is improved by integrating a plurality of MEMS dies of the same or different structures and functions on the same device wafer.
US11667513B1 Access control and metering of liquid storage tanks
A fluid access and control system for controlling access to a fluid storage tank includes a pump, a valve, a communications device, and controller. The pump is configured to supply a fluid output from the fluid storage tank. The valve is configured to control the fluid output of the pump. The communications device is configured to communicate with both a portable electronic device and a remote server. The communications device receives an access request from the portable electric device and transmits the access request to the remote server for validation. The controller is configured to control the operation of the pump and valve as defined by control signals transmitted by the remote server and received by the communications device. The controller is further configured to activate the pump and open the valve when the access request has been validated by the remote server and a START switch is actuated.
US11667512B2 Dispensing system for dispensing a liquid from a replacement container
A dispensing system including a container and a dispenser. In some embodiments, the container includes a container body, a dispensing opening, and a seal over the dispensing opening. In some embodiments, the dispenser includes a base, a drawer, a piercing tube, and a dispensing tap. In some embodiments, the base is configured to receive the container. In some embodiments, the drawer is moveable relative to the base between a first position and a second position. In some embodiments, the piercing tube is coupled to and moveable with the drawer. In some embodiments, the dispensing tap is in fluid communication with the piercing tube. In some embodiments, the piercing tube is configured to pierce the seal of container when the container is received in the base and the drawer is moved from the first position to the second position.
US11667504B2 Forks for industrial vehicles and method of making same
A fork for an industrial vehicle such as a forklift, and a method of making the same. The fork includes an elongate body portion, a toe portion, and, optionally, a heel portion. The elongate body portion may be formed in any length and coupled to the toe portion (and optionally, to the heel portion) to form a fork.
US11667502B2 Industrial truck, configured for driverless, autonomously acting operation for a load to be transported
An industrial truck, configured for driverless, autonomously-acting operation for a load to be transported, includes at least a control system configured to control and to steer the industrial truck, and an evaluation unit configured to generate a signal for stopping the industrial truck. A detector device configured to recognize persons and/or objects located in a route is connected to the control system. The control system is configured to check a protective field and/or a warning field of the detector device, and the protective field and/or the warning field is automatically switchable in dependence on a position of the industrial truck and/or detected obstacles in the route of the industrial truck.
US11667501B2 Two-post vehicle lift and adapter system for material, handling vehicles
A two-post vehicle lift system includes first and second posts extending longitudinally upwards from a floor. First and second carriages are slidably engaged with the first and second posts respectively. First and second swing arms are pivotally attached to the first carriage. Third and fourth swing arms are pivotally attached to the second carriage. First, second, third and fourth swing arm platforms are engaged with the first, second, third and fourth swing arms respectively. Each swing arm platform is positionable radially relative to its engaged swing arm. An adapter system is engageable with at least one swing arm platform and operable to be positioned to engage and lift a material handling vehicle. The adapter system includes one of a low profile adapter with a height adjustment mechanism, a low profile adapter with an outrigger arm capture mechanism, and an extended profile adapter with an outrigger arm capture mechanism.
US11667497B2 Wall climbing elevator
An illustrative example embodiment of an elevator includes an elevator car and a drive mechanism connected with the elevator car. The drive mechanism moves with the elevator car in a vertical direction. The drive mechanism includes drive members that are configured to engage surfaces associated with walls near opposite sides of the elevator car, climb along the surfaces to selectively cause movement of the elevator car, and selectively prevent movement of the elevator car when the drive members remain in a selected position relative to the wall.
US11667494B2 Mechanism for improving safety for an elevator system
A safety control device applicable to an elevator system including an elevator car driven in an elevator shaft by means of a drive device, said safety control device comprising at least one sensor configured to detect, in the elevator shaft, a presence of an object in at least one specified area of the elevator shaft, and a controller configured to receive and process a signal of the at least one sensor indicating a detection result, and to conduct, when the detection result indicates the presence of an object in the at least one specified area of the elevator shaft, a safety procedure in which a switch from a normal drive control of the drive unit to a safety drive control is executed in which a target value set for the speed of the elevator car is decreased.
US11667491B2 Sheet post-processing apparatus
The present invention is to enable folding processing to be applied to also large sheet sizes without upsizing the entire apparatus, in the sheet post-processing apparatus for performing the folding processing and binding processing on sheets, a sheet post-processing apparatus is provided with a binding processing section for performing binding processing using a binding needle on a sheet bunch inside a storage section, first folding roller pair for nipping a sheet P inside the storage section in a first position to form a first fold portion, a receiving section for receiving the sheet with the first fold portion formed fed out of the first folding roller pair, and second folding roller pair for nipping the sheet inside the receiving section in a second position to form a second fold portion.
US11667488B2 Sheet stacking apparatus and image forming apparatus provided with the same
In order to provide a sheet stacking apparatus for maintaining alignment characteristics of long-length sheets, the sheet stacking apparatus is a sheet stacking apparatus located above in a pair of sheet stacking apparatuses provided to overlap vertically along a vertical direction, and is provided with a first stacking section for stacking sheets, a second stacking section provided to extend from a downstream end of the first stacking section in a sheet transport direction and connected to the first stacking section rotatably, and a third stacking section which is attached to the second stacking section to extend from a downstream end of the second stacking section in the sheet transport direction, includes an inclined angle with respect to a horizontal surface smaller than in the second placing face, and which is attachable and detachable with respect to the second stacking section in a rotation direction.
US11667487B2 Emergency stop cutting mechanism for a web rewinding device
This invention provides web-cutting mechanism that can be mounted in line at an appropriate location between the web-handling peripheral (printer) and a web roll. The cutting mechanism operates before the available storage in the winder festoon has been exhausted, and decouples the roll's energy from the web. The cutting mechanism can employ a blade that is drawn through the web solely by the movement of the web itself. The blade is mounted at a (e.g.) 45-degree angle to web travel, causing it to be pulled through the web. A negator spring assembly and associated cable drives the blade into the side edge of the web when a slide-mounted blade shuttle assembly is released by a latching pawl of a solenoid assembly. The solenoid is triggered by a signal indicating an emergency stop condition, such as an upstream jam.
US11667482B2 Consolidated transportation method and consolidation terminal
According to one embodiment, a consolidated transportation method arranges a plurality of baggage in a same transportation area and performs transportation. A consolidation determination item is defined. A first baggage corresponding to an easily transferred baggage item in the consolidation determination item is arranged in a first transportation area and transported. A second baggage corresponding to a highly sensitive baggage item in the consolidation determination item is arranged in a second transportation area and transported. A first transporter includes the first transportation area. A second transporter includes the second transportation area. The first transportation area and the second transportation area are physically separated.
US11667473B2 Conveyor sensor
Some embodiments of the technology disclosed herein relate to a sensor device. An elongate sleeve has a first end and a second end and extends along a longitudinal axis. A plurality of sensors are fixed relative to the sleeve. A first endcap is coupled to the first end, where the first endcap has an endcap body. A first axle is coupled to the endcap body, where the first axle extends along the longitudinal axis and the first axle defines a retaining feature. An intermediate component is coupled to the first axle, and the intermediate component is selectively rotatable about the longitudinal axis. The sensor device has an orientation locking structure that is configured to be engaged to selectively fix the orientation of the intermediate component about the longitudinal axis relative to the endcap body.
US11667457B2 Packaging bag and packaged product
A packaging bag for packaging water-absorbent resin powder includes a resin sheet with gas barrier properties which is formed in a bag shape having a charge opening for charging the water-absorbent resin powder into the packaging bag. At least one resin sheet piece of the resin sheet is provided with an incision penetrating the resin sheet piece in a thickness direction thereof, the incision having a dimension not larger than a predetermined length according to a mass median particle size of the water-absorbent resin powder.
US11667454B2 Packaging box for cooling
Provided is a packaging cooler box for delivery, comprising a bottom portion to form a lower surface upon conversion into a box mode, a plurality of sidewall portions configured to connect with the bottom portion, a lid portion configured to connect with one of the sidewall portions, and to face said bottom portion upon conversion into the box mode, a crease portion formed along the edge of the bottom portion so that the sidewall portions can stand upright, joint portions configured to join said sidewall portions, to be folded to face itself and to be in close contact with the sidewall portions, upon conversion into the box mode, and easy adhesive portions provided in said joint portions and sidewall portions to maintain the box shape upon conversion into the box mode from a single plane consisting of said bottom portion, sidewall portions, said lid portion and joint portions.
US11667453B2 Apparatus and system for authenticating, grading, and encapsulating collectibles
A computer system generates information describing authenticity and a grade of a collectible scanned by a scanning device. A feature vector is extracted from the information. The feature vector includes a first set of features and a second set of features. The first set of features is matched to authenticity profiles of collectible items. Each authenticity profile characterizes at least one collectible item across multiple features. A confidence score is generated with respect to the authenticity of the collectible based on the authenticity profiles. The second set of features is matched to grade profiles of the collectible items. A grade score describing the grade of the collectible is generated based on the grade profiles. The grade of the collectible is determined based on the grade score. A graphical representation of the grade and the confidence score is transmitted to a display device.
US11667452B2 Edge protector
A sheet of foldable material having a plurality of laterally spaced parallel fold lines dividing the sheet into consecutive panels to allow for folding of the panels into overlapping engagement. A notched edge protecting section comprising at least two panels folded into an overlapping engagement and formed from the removal of material from the overlapping panels. An un-notched edge protecting section comprising at least two panels folded into an overlapping engagement and including a first and second leg each having an inner longitudinal edge, outer longitudinal edge and an outside edge wherein the angle between said first longitudinal edge and said outside edge is greater than 90 degrees. A third and a fourth leg formed from the folding of said un-notched edge protecting section so that at least a portion of the inner longitudinal edges of the first and second legs contact one another.
US11667449B2 Reseal label for box in a box re-sealable pack
A container includes a rigid outer box and a rigid inner box wherein a pull tab is configured to reseal a pre-cut opening in the inner box. The pull tab includes a cover layer larger than the pre-cut opening. The cover layer can be a piece of bundle wrap with a paper layer of the bundle wrap contacting the consumer goods inside the box. The outer box has a hinged lid permanently attached to a connecting tab of the pull tab whereby opening the hinged lid simultaneously opens the pre-cut opening in the inner box by lifting the pull tab. The connecting tab includes adhesive which is partially deadened to decrease adhesion of the connecting tab to the inner box. The pull tab can also include one or more machine readable markings to enhance automated application of the pull tab to an inner box blank during manufacturing of the container.
US11667447B2 Can retaining apparatus and advertising platform
A can retaining apparatus and advertising platform comprising a strip with an upper surface, a lower surface and a perimeter edge. The strip is preferably rectangular shaped and can be made of various materials including polyethylene terephthalate (PET), polyethylene terephthalate glycol (PET G), plastic, metal, wood, rubber, fabric, vinyl, cardboard or a composite. Located on the strip is at least one, and preferably multiple retaining members, configured as an arrow structure within an oval opening, and onto which a can is secured and captively held. Also, on the strip is at least one, and preferably multiple, advertising sections. Each advertising section is configured to display product or promotional information from a company or organization. The advertising sections are either printed on, or are a substrate attached by attachment means, such as adhesive. A scannable image on the strip allows information to be stored and transferred to a person using the apparatus and platform.
US11667446B2 Rolled paper product cargo assemblages and method for making rolled paper product cargo assemblages
Aspects of the present disclosure relate to cargo assemblages that may include containers of rolled products stacked on pallets secured thereto with film and methods of producing such cargo assemblages. The load may include containers of absorbent paper product arranged in stacked layers from a bottom layer of containers to a top layer of containers. A film may be applied to connect the load with the pallet and to connect neighboring stacked layers together. The film may be wrapped around the pallet and/or layers of containers with a wrap profile having different characteristics, such as for example, containment forces; tensions; numbers of layers, and/or locations of layers with respect to the load, the pallet, and/or each other.
US11667438B2 Replacement gripping member
An improved gripping member for a weight bearing container. The gripping member is specifically designed to either replace an existing gripping member, or improve a two part handle for a weight bearing container by providing a larger diameter gripping surface. The improved gripping member is formed of two identical mating halves that can be releasably attached to form a cylindrical gripping surface with a relatively large diameter. When attached about an existing gripping member or wire handle portion of a two part handle the inventive gripping member provides a large diameter gripping surface to distribute the weight of the container about a larger portion of the user's palm.
US11667436B2 Closed-head drum with liner, and method for producing the same
The present invention relates to a closed-head drum (10) with inserted thin-walled inliner (22) of multilayer plastic film for storing and transporting liquid or free-flowing filling materials. In order to improve the use of liners in closed-head drums, and to facilitate in particular the handling for the users such as the filling and emptying operators, so as to allow the closed-head drum (10) with liner (22) to be handled in precisely the same way as a closed-head drum without a liner, the present invention provides for the liner surface to adhere, or be adhesively bonded in a detachable manner, to the inner wall of the drum by virtue of a vacuum being created in the intermediate air space between the inner wall of the drum and liner surface and by thermal activation by means of hot air injection into the interior of the inliner.
US11667435B2 Container, preform assembly and method and apparatus for forming containers
Container comprising an inner container and an outer container with facing surfaces, wherein at least part of at least one of the facing surfaces has a surface roughness higher than about 0.1 Ra and/or wherein the difference in roughness of the facing surfaces is at least over a part more than about 0.1 Ra.
US11667434B2 Anti-counterfeiting measures for glass articles
A glass container including a body having a delamination factor less than or equal to 10 and at least one marking is described. The body has an inner surface, an outer surface, and a wall thickness extending between the outer surface and the inner surface. The marking is located within the wall thickness. In particular, the marking is a portion of the body having a refractive index that differs from a refractive index of an unmarked portion of the body. Methods of forming the marking within the body are also described.
US11667430B2 Self-sealing container
A self-sealing container is formed from a blank comprising panels and end flaps connected along fold lines with the panels and the end flaps being foldable along the fold lines to form the container. The container includes a securing feature that seals the container in a closed position, with the securing feature providing a visual indication of opening if the container is opened from the closed position. After the container is opened, the securing feature provides a closure feature that allows the container to be closed.
US11667428B2 Sheet packaging matertial for producing a sealed package containing a pourable product and a package obtained therefrom
A sheet packaging material for producing a sealed package comprises two first boundary edges parallel to a longitudinal direction and two second boundary edges parallel to a transversal direction orthogonal to the longitudinal direction. The sheet packaging material includes at least a bottom transversal crease line including a bottom central portion, a bottom end portion and a bottom side portion. The sheet packaging material includes a pair of slanted crease lines inclined relative to both the longitudinal and transverse directions. The slanted crease lines have first ends pointing to one of the second boundary edges and second ends pointing to a continuous line parallel to the transversal direction and including the bottom central portion and the bottom end portion. The slanted crease lines delimit, with the bottom side portion, a flap area of the sheet packaging material designed to form at least part of a lateral flap of the package.
US11667427B2 Stackable receptacle for the shipment of goods
Embodiments of a reusable stackable shipping box are provided herein. The reusable stackable shipping box may be reused and cleaned without causing harm to the integrity of the box. In addition, the box is slightly tapered in shape such that the box may be stacked upon and within other boxes for ease in shipping and organization.
US11667424B2 Liquid container labelling machine with optical inspection device
This invention relates to a machine and a method for labelling and inspecting containers for liquids, automatically applying a label on each container on a seamless zone of it, using an optical inspection device provided with an illuminator having a collimator interposed between a light generator of the illuminator and a carousel of the machine.
US11667423B2 Stretch film dispenser
A stretch film dispenser includes a frame. The frame has a top seat and a bottom seat. The top seat and the bottom seat are jointly equipped with a film mounting unit and a film dispensing unit. The film dispensing unit includes a first roller and a second roller. The first roller and the second roller have a strip hole. The strip hole is located between the first roller and the second roller. Through the strip hole of the first roller and the second roller, the front end of a film can pass through the strip hole between the first roller and the second roller easily and quickly, and the film is pulled out along the direction of the first roller, thereby achieving the effect of easy and convenient installation of the film.
US11667419B2 Apparatus for bagging a bale and method of bagging such bale
A bale bagging apparatus and method are provided. The bale bagging apparatus includes a bale feeding station, a bale chute, a bale bagging station, and a transportation system that transports a bale to be bagged from the bale feeding station through the bale chute and into the bale bagging station. The bale bagging station includes a bag receptacle, a first opening, and a bag retrieval assembly. The bag receptacle is positioned on a side opposite of the first opening from the side of the first opening on which the bale to be bagged is to be transported. The bag retrieval assembly retrieves a bag from the bag receptacle through the first opening. The bag retrieval assembly positions a first end of said bag around at least a portion of the bale chute before the bale to be bagged is transported through the bale chute by the transportation system.
US11667418B2 Strapping apparatus
A strapping apparatus for strapping articles with a strapping band having a tensioning device for imparting a band tension to a loop of the strapping band, the tensioning device including a driveable tensioning element provided for engaging the strapping band to impart a band tension. The strapping apparatus including a connecting device for generating a permanent connection, in particular a welded connection, at two regions, situated one above the other, of the loop of the strapping band. The strapping apparatus is configured to achieve the release of the tensioning element from the strapping band reliably to avoid or reduce adverse characteristics attributed to the release of the tensioning device from the band.
US11667417B2 Strapping device having a pivotable rocker
Various embodiments of the present disclosure provide a mobile strapping device for strapping packaged products using a loop of wrapping strap. The strapping device includes a tensioning device for applying tension to the strap and a connecting device for connecting two overlapping portions of the strap. The tensioning device includes a rotatable tensioning wheel and a tensioning plate. The tensioning wheel is supported by a rocker that is pivotable to change a distance separating the tensioning wheel and the tensioning plate. The mobile strapping device includes a motor that is operably connectable to the rocker or the tensioning wheel such that the motor causes pivoting of the rocker or rotation of the tensioning wheel when operating in a first direction of rotation. In various embodiments, gearing, including a plurality of planetary gear sets, is used to operatively connect the motor to the rocker and the tensioning wheel.
US11667411B2 Flap folding unit, flap folding apparatus, flap folding method and systems and methods using the same
A flap folding unit (90) for folding flaps of lids of boxes, comprising a hinged guiding element (94) adapted for contacting a flap to be folded upon relative movement of the guiding element and the flap and guiding the flap towards its intended final position and an extendable pusher (96) adapted for pushing the flap into its intended final position.
US11667407B2 System and method for automated intercept avoidance for spacecraft
Embodiments in accordance with the invention address potential co-orbital threats to a spacecraft through the use of a plurality of evasion pattern maneuvers selected to prevent a rendezvous with a potential co-orbital threat from occurring within a finite horizon. Embodiments in accordance with the invention maintain separation from the potential co-orbital threat while minimizing a defending spacecraft's fuel consumption.
US11667406B1 Inertial stabilization system with active jitter suppression and optical control
A three-loop inertial stabilization system with active jitter suppression and optical control to reduce line-of-sight (LOS) jitter based on platform induced motion in cantilevered gimbal systems. A first loop comprises at least one rate sensor, a Kalman state estimator, and a rate to angle module. A second loop comprises a mirror system, a focal plane and centroid processing module, an open-loop closed loop selector, a signal combiner and a loop integrator. A third loop comprises a fast steering mirror, offload module and at least one gimbal motor driver, wherein the three loops suppress the jitter of the cantilevered gimbal system.
US11667402B2 Landing pad with charging and loading functionality for unmanned aerial vehicle
A landing pad for an unmanned aerial vehicle (“UAV”) is disclosed. The landing pad includes a support structure, a charging pad, and a plurality of movable UAV supports. The charging pad is coupled to the support structure and able to move relative to the support structure. The UAV supports are also coupled to the support structure and configured to translate along the support structure from a first position to a second position. When the UAV supports are in the first position, the charging pad supports the UAV. When the UAV supports are in the second position, the charging pad is lowered and the UAV supports then provide support to the UAV.
US11667400B2 Tram system and methods for autonomous takeoff and landing of aircraft
One variation of a tram system includes: a chassis; a latch configured to selectively engage a latch receiver mounted to an aircraft; an alignment feature adjacent the latch and configured to engage an alignment receiver mounted to the aircraft and to communicate acceleration and braking forces from the chassis into the aircraft; an optical sensor facing upwardly from the chassis; a drivetrain configured to accelerate and decelerate the chassis along a runway; and a controller configured to detect an optical fiducial arranged on the aircraft in optical images recorded by the optical sensor adjust a speed of the drivetrain to longitudinally align the alignment feature with the alignment receiver based on positions of the optical fiducial detected in the optical images, trigger the latch to engage the latch receiver once the aircraft has descended onto the chassis, and trigger the drivetrain to actively decelerate the chassis during a landing routine.
US11667399B2 Deck landing system for aircrafts
A deck landing system for aircrafts, in particular rotating wing aircrafts, apt to implement a hook between the aircraft and the deck of a ship or of a floating platform, the deck being equipped with a target grid plate, it does not require the use of hydraulic systems and it comprises: a telescopic actuator (1) with a harpoon (3) having, at its own distal end, hooking grippers (7); and a control unit (9) which actuates said telescopic actuator (1), wherein the telescopic actuator (1) comprises a linear electromechanical actuator (8) having: a main battery (13) fed through a unit (12) for converting and conditioning the energy and connected to said telescopic actuator (1); and a device (10) for recovering and releasing the kinetic energy generated by the waves with the aircraft locked on said deck, is of the type acting with super-capacitors, which feeds said main battery (13).
US11667398B2 Multicopter-assisted systems and methods for launching and retrieving a fixed-wing aircraft into and from free flight
The present disclosure presents various embodiments of a system for retrieving a fixed-wing aircraft from free flight using a flexible capture member. The system includes a GPS reference sensor and a communication link to guide the fixed-wing aircraft to intercept the flexible capture member.
US11667390B2 Systems for aircraft landing after ejection
A system for controlling an aircraft in response to deployment of an ejection seat may comprise a seat controller located on the ejection seat and configured to output a signal in response to initiation of an ejection sequence. An aircraft controller may be configured to receive the signal from the seat controller. A tangible, non-transitory memory may be configured to communicate with the aircraft controller. The tangible, non-transitory memory may have instructions stored thereon that, in response to execution by the aircraft controller, cause the aircraft controller to perform operations, which may comprise receiving the signal from the seat controller, receiving data signals from an operational data source, and sending command signals configured to control a component of the aircraft.
US11667389B2 Release mechanism device, parachute systems and parachute stabilization
An article of manufacture, a force reduction release mechanism and system for selectively maintaining and releasing components under tensile tension, the release mechanism offering mechanical gain such that the force required to activate a release between the components is a mere fraction of the heavy tensile tension force. Other aspects of the invention include novel cargo parachute system utilizing the release mechanism and a parachute stabilization arrangement utilizing at least one releasable stabilization anchor.
US11667387B2 Ice protection and boundary layer suction system for an aircraft aerofoil
A system for suction of the boundary layer of a wing and protection against icing of this wing includes a wall including micro-perforations and delimiting a leading edge extended by a pressure-side wall and by a suction-side wall. The system also includes a perforated tube running along the leading edge, an exhaust duction for sucking air from this tube in order to suck the boundary layer successively via the micro-perforations of the wall and via the perforations of the tube, and a supply duct for blowing hot air into this perforated tube during a phase of protection against icing, this hot air being discharged successively via the perforations of the tube and via the micro-perforations of the wall.
US11667382B1 Systems and methods for utilizing unmanned vehicles to facilitate claims processing
This disclosure relates to utilizing unmanned vehicles for insurance claim processing. For example, a UAV may be directed to proceed to a target location, which obstructions to avoid and how to avoid them, and what data needs to be gathered about the target. Thus, one or more embodiments described herein relate to navigating to a target location based on receiving a first location of the vehicle and a second location of the target, avoiding obstructions, gathering data about a structure at the target, and initiating an insurance claim.
US11667381B2 Circuit, terminal device, base station device, and method
A circuit includes an acquisition unit configured to acquire information regarding a flight and a measurement report control unit configured to control a measurement report process on a reference signal transmitted from a base station device, on a basis of the information regarding the flight acquired by the acquisition unit.
US11667378B2 Flap drive device and blades of rotary-wing aircraft
Provided are a flap drive device and a rotorcraft blade, and more particularly, a flap drive device using a two-section link mechanism, which may be applied to a rotorcraft blade, and a rotorcraft blade including the same.
US11667376B1 System and method for flight control compensation for component degradation
A system and method for flight control compensation for component degradation is illustrated. The system comprises a first flight component mechanically coupled to the electric aircraft and a second flight component mechanically coupled to the electric aircraft. A sensor is also coupled to both the first flight component and the second flight component, wherein the sensor is configured to detect a performance degradation datum in one of the first flight component and the second flight component and transmit the performance degradation datum to a flight controller. The system also comprises a flight controller communicatively coupled to the sensor, wherein the flight controller is configured to receive the performance degradation datum from the sensor and adjust operation of either the first flight component or the second flight component as a function of the performance degradation datum.
US11667374B2 Blade pitch actuation mechanism
A blade pitch actuation mechanism comprising a rotating race member in which is formed a race configured to receive a trunnion pin attached to a blade, whereby the race defines a cam profile such that rotation of the race member causes the trunnion pin received in the race to rotate as it slides over the cam profile.
US11667373B2 Elevon control system
A system comprising an aerial vehicle or an unmanned aerial vehicle (UAV) configured to control pitch, roll, and/or yaw via airfoils having resiliently mounted trailing edges opposed by fuselage-house deflecting actuator horns. Embodiments include one or more rudder elements which may be rotatably attached and actuated by an effector member disposed within the fuselage housing and extendible in part to engage the one or more rudder elements.
US11667372B2 Drone systems and methods
An aircraft includes a body defining an interior compartment configured to hold at least one of a passenger and a payload, a battery system, a plurality of arms coupled to and extending from the body, and a plurality of propulsion devices configured to provide thrust to fly the aircraft. Each of the plurality of propulsion devices is coupled to a respective one of the plurality of arms. The plurality of propulsion devices are powered by the battery system. Each of the plurality of propulsion devices is selectively pivotable about at least one axis. The plurality of propulsion devices include at least one of (i) counter rotating ducted fans and (ii) ionizing electrode engines.
US11667371B2 Composite materials having reinforced access openings
Structurally reinforced composite components are disclosed having access openings reinforced to increase strain load and buckling load without adding weight to the composite components by inducing out-of-plane regions proximate to the access opening during composite prepreg laminate layup.
US11667367B1 Marine muffler with integral bypass water management
A marine muffler capable of handling both marine engine exhaust gas and marine engine cooling water includes a double wall baffle partitioning the muffler interior so as to function as a cooling water conduit. The cooling water conduit includes an inlet disposed external to the main muffler housing and an outlet configured and disposed so as to discharge the engine cooling water into the exhaust duct connected to the muffler outlet. The muffler is thus able to convey the engine cooling water through the muffler housing within a dedicated conduit while maintaining the cooling water separate from the exhaust gas. A muffler that is adapted to handle both the exhaust and cooling water flowing from a marine engine allows for the elimination of engine cooling water piping.
US11667362B2 Diving mask provided with a telecommunications device
The invention relates to a diving mask (10) including a frame (12) fitted with a visor (18); a flexible skirt (40) including a partition (46) delimiting an upper chamber (50) for viewing from a lower chamber (52) for breathing, the partition being arranged to bear upon the nose of the user such that the mouth and the nose of the user are in the lower chamber, while the eyes of the user are in the upper chamber, a breathing tube (20) having a proximal end (20a) for linking the breathing tube to the frame, the breathing tube including at least one channel (21) fluidically connected with the lower chamber. The diving mask further includes a telecommunications device (500) which is mounted at least partially to the breathing tube (20).
US11667360B1 Hard shell boat cover
A hard shell boat cover is disclosed herein. The hard shell boat cover includes a plurality of boat cover sections, the plurality of boat cover sections configured to interlock with one another so as to form the hard shell boat cover, and one or more of the plurality of boat cover sections configured to engage with a top peripheral edge of a boat; and at least one securement element attached to one of the plurality of boat cover sections, the securement element configured to be coupled to a securement strap for securing the hard shell boat cover to the top peripheral edge of the boat.
US11667358B2 Watercraft
The invention relates to a watercraft, particularly a kayak having a battery compartment and motor mount for mounting a motor thereto. The kayak can be propelled either by a motor mounted to the motor mount or by manual paddling by a user of the kayak. The kayak may additionally have a seat mounted onto a track to allow the user to adjust their position as needed in the kayak. The kayak is extra wide to provide stability, while chamfered side walls allow the user to paddle with comfort regardless of the extra width. The kayak may optionally have wheels mounted thereon to facilitate handling and transport by the user.
US11667355B2 System and method for launch and recovery of a marine vessel
The present invention provides a capturing mechanism and method for the recovery of at least one vessel to at least one marine platform; the at least one vessel having at least one engagement device either permanently or at least partially reversibly connectable to the same; the capturing mechanism including: a. at least one tensioned capturing line connected to the at least one marine platform; and b, at least one line maneuvering mechanism configured to displace the at least one tensioned capturing line in at least one direction selected from a group of up, down, left, right, forward, backward, playable into the at least one marine plat form, playable out of the at least one marine platform, playable into and out of the water and any combination thereof.
US11667354B2 Whitewater boat strap
A boat strap is described herein, as well as a system and method of attaching two boats with the boat strap. The boat strap is made up of a main strap, a free cam, a lower cam strap, and a lower cam. The free cam is mechanically connected to the main strap, where the main strap loops through a free cam strap connector. Additional stitching connects the main strap to itself forming a free cam loop to connect the free cam to the main strap. The lower cam is mechanically connected to the lower cam strap. The lower cam strap loops through a lower cam strap connector, and a primary stitching connects the lower cam strap to itself forming a lower cam loop to connect the lower cam to the lower cam strap, wherein the primary stitching further connects the lower cam strap to the main strap. The main strap loops through a connector on one boat and runs through the lower cam to attach the boat strap to the rail. The main strap then is run through the cam on a second boat strap on the other boat, attaching the boats.
US11667352B2 Foiling watercraft
A personal watercraft comprising a body having a seat and a hull, the seat configured to support a user with the body floating in water, a plurality of hydrofoils extending outwards from the body and coupled to a positioning system, the plurality of hydrofoils being configured, in combination, to raise the hull of the personal watercraft above a waterline in the water when the personal watercraft is in use and under the influence of a propulsion force, one or more sensors that provide sensor data of the watercraft during use, a computer-readable medium having a processor and a memory having instructions that, when executed by the processor read the sensor data, and based on the read sensor data, send a signal to the positioning system to adjust the position for at least one of the plurality of hydrofoils.
US11667351B2 Systems and methods for automatic configuration and automatic calibration of continuously variable transmissions and bicycles having continuously variable transmission
A continuously variable transmission on a bicycle may be automatically configured with little or no assistance from a user. Optical scanning devices, RFIDs, and other information capturing technology can communicate with a controller. The controller may then perform a portion or all of a configuration process. In operation, a controller may determine that calibration is needed. A calibration process may be initiated and performed with little or no user interaction. A calibration process may account for a load, a power source, or an environment.
US11667350B2 Damper for a bicycle component
A bicycle rear derailleur includes a movable member and a chain guide assembly rotatably connected to the movable member. The bicycle rear derailleur also includes a pivot member non-rotatably coupled to the chain guide assembly and having an outer annular surface, a biasing device configured to bias the chain guide assembly in a first rotational direction relative to the movable member, and a damper device disposed between the chain guide assembly and the movable member. The damper device is operable to apply a damping force to the chain guide assembly when the chain guide assembly rotates in a second rotational direction relative to the movable member. The damper device includes a friction device that is radially inner relative to the biasing device. The friction device includes a friction member having at least one friction surface biased against and in frictional engagement with the pivot member.
US11667349B2 Bicycle rear derailleur
A bicycle rear derailleur includes a seat assembly, a movable component, a linkage assembly, and a chain guide. The seat assembly includes a first seat body, a second seat body, and a shaft. The shaft is disposed through the first seat body and the second seat body and configured to be mounted on the bicycle frame, and the second seat body is configured to connect the first seat body with the bicycle frame. The linkage assembly connects the movable component with the first seat body. The chain guide is pivotably disposed on the movable component. The first seat body is movable towards or away from the second seat body along a central line of the shaft.
US11667345B1 School children rescue vehicle
A school children rescue vehicle is provided. The vehicle includes an electric mobility scooter assembly. The vehicle includes a protective shell configured to attach to the assembly. The protective shell includes a plurality of hardened flat panels configured to connect between themselves and form an overall 5-sided shaped enclosure and arranged to fit on top of and connect to the electric mobility scooter assembly and structured to provide projectile protection for personnel situated within the protective shell. The shell includes a plurality of viewing ports of bullet proof glass positionable within the hardened flat panels and configured to provide line of sight viewing for personnel inside the protective shell. The overall external dimensions of the protective shell are such that the vehicle can maneuver within tight enclosed spaces. The vehicle functions as a deterrent to school violence and as a rescue vehicle for an active shooter situation.
US11667342B2 Active track-chain sag management systems for crawler vehicles
An active track-chain sag management system for usage in conjunction with crawler vehicles having tracked undercarriages includes a movable track-engaging member positioned for physical engagement into a track-chain of the tracked undercarriage, an electric drive assembly controllable to adjust a track-tensioning position of the movable track-engaging member relative to the track-chain, and a controller operatively coupled to the electric drive assembly. The controller is configured to command the electric drive assembly to repeatedly adjust the track-chain sag of the track-chain by varying the track-tensioning position of the movable track-engaging member during operation of the tracked undercarriage.
US11667339B2 Electric bus with seats over driving wheels
An articulated electric bus includes two units with: a passenger compartment including a main floor forming a low and thin platform with a planar surface extending over the majority of the width of the passenger compartment, a wheel housing adjacent to the planar surface, a longitudinal row of seat places on the wheel housing, and a driving wheel which is housed in the wheel housing under the longitudinal row of seats. The driving wheel defines a rotation axis and includes an electric engine, and a rim with a rim top above the planar surface. The driving wheel is vertically movable with respect to the planar surface, and the wheel housing actually receives a pair or a couple of driving wheels.
US11667335B2 Counteracting backdrive in a power tailgate system
Embodiments of systems and methods for operating a power tailgate system are disclosed. A vehicle includes a rotatable element structured for operable connection with, and disconnection from, a tailgate when the rotatable element resides in a predetermined tailgate removal orientation. A motor is connected with the rotatable element for interdependent movement, and a motor circuit is provided for the motor. During a driving event, the system identifies when no tailgate is connected with the rotatable element. If no tailgate is connected with the rotatable element, the system determines if the rotatable element resides in the predetermined tailgate removal orientation. If the rotatable element resides in the predetermined tailgate removal orientation, the system may check the rotatable element against rotation during the driving event by operating a motor circuit to electrically brake the motor to prevent the rotatable element from rotating out of the predetermined tailgate removal orientation.
US11667331B2 Vehicle body
A vehicle body including side is provided. The vehicle body includes left and right side frames that extend in a vehicle body forward-rearward direction and support a collision load acting from the front or the rear, and a coupling member that is joined to open ends of the side frames and restricts displacement between the open ends in a direction in which the open ends are away from each other. The side frame has a plurality of low-strength sections disposed with high-strength sections interposed therebetween in the vehicle body forward-rearward direction and having a lower strength than the high-strength sections in the vehicle body forward-rearward direction. The low-strength section closer to the open end has a lower strength in the forward-rearward direction.
US11667329B2 Lane change assist apparatus for vehicle
A driving support Electronic Control Unit (ECU) initializes a target trajectory calculation parameter at a start of Lane Change Assist Control (LCA), calculates, based on the target trajectory calculation parameter, a target trajectory function representing a target lateral position in accordance with an elapsed time from the start of LCA; and calculates a target control amount according to the target trajectory function. When it is determined that the own vehicle has crossed a boundary white line, the driving support ECU again initializes the target trajectory calculation parameter, and calculate the target trajectory function based on the target trajectory calculation parameter.
US11667326B2 Automatic guidance performance improvement and transport with articulated machine form
Operating a vehicle in an automated steering control mode wherein the vehicle includes a controller operatively coupled with an articulated steering system and a front axle steering system. The controller is configured to identify a desired path of curvature of the vehicle and determine a front axle steering angle of the front axle steering system and command the front axle steering system to operate at the front axle steering angle and also determine an articulation steering angle of the articulated steering system and command the articulated steering system to operate at the articulation steering angle. A further form includes operating front and rear ground engaging means at a designated speed, and thereafter operating the articulated steering system and the front axle steering system based on the designated speed being greater than a transport speed threshold, less than a field speed threshold or between the two.
US11667322B2 Steering column assembly
A steering column assembly is disclosed that comprises: an elongate rotatable steering column, a displacement motor, a torque feedback motor; an engagement mechanism and a control. The steering column is configured at one end for attachment of a steering member and is displaceable along its longitudinal axis between a withdrawn, stowed position in which the steering function of the steering column is inhibited and an extended, deployed position in which the steering function of the steering column can be enabled. The displacement motor displaces the steering column between the stowed and deployed positions. The torque feedback motor is connected to the steering column and by which the steering column is rotatable. The engagement mechanism is engaged when the steering column is in the stowed position and limits the angular displacement of the steering column to a predetermined value. A control is configured to control the operation of the displacement motor and torque feedback motor and to inhibit and enable the steering function of the steering column.
US11667313B2 Foldable frame for a cart
This utility model discloses a foldable frame for a cart, including the front wheel unit part, the rear wheel unit part, the side-wall connection structure, the scissor structure I, the scissor structure II, the bottom support structure. The said scissor structure I is movable-connected on the front wheel unit part, and both the said scissor structure II and the scissor structure I have the same structure and are connected on the rear wheel unit part. Two groups of the said side-wall connection structure are provided and they are respectively connected on the front wheel unit part and the rear wheel unit part on the same side. Totally, the said bottom support structure are movable-connected to two groups of the said front wheel unit part and the rear wheel unit part. This utility model belongs to the technology field of the frame for a cart.
US11667310B2 Control device, control system, railway vehicle and associated control method
A control device is for at least two traction engines of a railway vehicle. The control device includes an estimation module configured to estimate a traction power requirement of the rail vehicle as a function of at least one position signal of the rail vehicle, a determination module configured to determine a required operating state of each engine based on the power requirement, an adaptation module configured to determine, from the required operating state of each engine, an adapted operating state of said engine as a function of at least one specific parameter relating to the operation of the rail vehicle, and an emission module configured to emit a control signal to each engine.
US11667307B2 Method and apparatus for controlling autonomous driving
A method for controlling autonomous driving for an autonomous driving vehicle, includes collecting sensing information on autonomous driving in an autonomous driving mode, calculating an initial longitudinal control value based on the sensing information on the autonomous driving, correcting the initial longitudinal control value based on the sensing information, and performing a longitudinal driving control by transmitting the corrected longitudinal control value to a lower controller.
US11667306B2 Method and system for dynamically curating autonomous vehicle policies
A system for dynamic policy curation includes a computing system and interfaces with an autonomous agent. A method for dynamic policy curation includes collecting a set of inputs; processing the set of inputs; and determining a set of available policies based on processing the set of inputs. Additionally or alternatively, the method can include any or all of: selecting a policy; implementing a policy; and/or any other suitable processes.
US11667303B2 Hands-off detection for autonomous and partially autonomous vehicles
Systems and methods for testing a hands-off detection algorithm. The method includes determining a plurality of system behavior test conditions for the algorithm and selecting an orthogonal array defining a plurality of test cases based on the plurality of system behavior test conditions. The method includes generating, for each of the test cases, an expected test outcome. The method includes for each of the test cases, conducting a test of with the vehicle based on the orthogonal array to generate a plurality of actual test outcomes and generating a response table based on the test outcomes, including a plurality of system behavior test condition interactions. The method includes determining, for each of the interactions, a result rating based on the expected test outcomes and the actual test outcomes and identifying, within the response table, which one or more of the test conditions exhibits a high failure condition.
US11667301B2 Symbolic modeling and simulation of non-stationary traffic objects for testing and development of autonomous vehicle systems
A system performs modeling and simulation of non-stationary traffic entities for testing and development of modules used in an autonomous vehicle system. The system uses a machine learning based model that predicts hidden context attributes for traffic entities that may be encountered by a vehicle in traffic. The system generates simulation data for testing and development of modules that help navigate autonomous vehicles. The generated simulation data may be image or video data including representations of traffic entities, for example, pedestrians, bicyclists, and other vehicles. The system may generate simulation data using generative adversarial neural networks.
US11667295B2 Apparatus and method for recognizing object
The present disclosure relates to an object recognition apparatus and method. Specifically, the object recognition apparatus according to the present disclosure comprises: an object information collector configured to collect object information based on driving information of a vehicle and surrounding detection information detected around the vehicle; an object selector configured to select an object corresponding to a predetermined first tolerance range based on the object information; a tolerance range setter configured to set a second tolerance range based on the driving information and the object information when a moving object exists among the objects corresponding to the first tolerance range; and a guardrail recognizer configured to determine whether the moving object falls within the second tolerance range based on the object information, and recognize a guardrail based on object information of the moving object corresponding to the second tolerance range.
US11667292B2 Systems and methods for vehicle braking
Systems and methods use cameras to provide autonomous navigation features. In one implementation, a method for navigating a user vehicle may include acquiring, using at least one image capture device, a plurality of images of an area in a vicinity of the user vehicle; determining from the plurality of images a first lane constraint on a first side of the user vehicle and a second lane constraint on a second side of the user vehicle opposite to the first side of the user vehicle; enabling the user vehicle to pass a target vehicle if the target vehicle is determined to be in a lane different from the lane in which the user vehicle is traveling; and causing the user vehicle to abort the pass before completion of the pass, if the target vehicle is determined to be entering the lane in which the user vehicle is traveling.
US11667291B2 Method and apparatus for vehicle braking
At least one embodiment of the present disclosure provides an apparatus for braking a vehicle, including a plurality of electro-mechanical braking (EMB) systems respectively installed for a plurality of vehicle wheels and configured to generate a braking force to the plurality of wheels, respectively, a driving information detecting unit for measuring driving information of the vehicle, an electronic power steering (EPS) system generating a steering torque in a direction opposite to a braking torque generated in the vehicle, and an electronic control unit (ECU) controlling the electro-mechanical braking systems and the electronic power steering system, wherein the electronic control unit is configured to control, upon determining that one or some of the plurality of electro-mechanical braking systems are malfunctioning, the vehicle by using the electronic power steering system, and the electronic power steering system is configured to generate the steering torque according to the driving information including wheel speeds.
US11667287B2 Vehicle and control device of the same
A control device of a vehicle is configured to control travelling of the vehicle such that the vehicle follows a preceding vehicle based on information received from the preceding vehicle, and determine, based on information regarding a cargo space of the preceding vehicle, an inter-vehicle distance to the preceding vehicle when the vehicles stop. Upon the preceding vehicle having stopped, the device stops the vehicle such that a distance between the vehicle and the preceding vehicle becomes the inter-vehicle distance determined by the device.
US11667285B2 Vehicle control method and apparatus, electronic device and storage medium
The present disclosure relates to adaptive cruise control in the field of automatic driving, and discloses a vehicle control method, an apparatus, an electronic device and a storage medium. A specific implementation is: firstly, determining a target travelling scenario according to real-time monitoring data upon fulfilment of a preset update condition; then, determining a target time headway according to the target travelling scenario, where the target time headway is used to dynamically adjust a relative motion state between an host vehicle and a surrounding vehicle; and finally, controlling a vehicle according to the target time headway. It solves the problem of the prior art in overemphasizing the state of the vehicle ahead for automatic driving control while overlooking the perception of the driver or passenger of the host vehicle in the travelling scenario can prompt the driver to manually intervene, compromising the experience of the automatic driving.
US11667281B2 Vehicle control method, vehicle control device, and storage medium
A vehicle control method includes recognizing an object, generating a target trajectory of a vehicle, and automatically controlling driving of the vehicle on the basis of the target trajectory, calculating a region between a first virtual line, which passes through a reference point using the vehicle as a reference and a first point present in the vicinity of an outer edge of the object, and a second virtual line, which passes through the reference point and a second point present in the vicinity of the outer edge of the object, as a region through which the vehicle should avoid to travel, and excluding the target trajectory present in the traveling avoidance region, and automatically controlling the driving of the vehicle on the basis of a remaining target trajectory remained without being excluded.
US11667279B2 Driving assistance apparatus
A driving assistance apparatus is configured to determine whether a preset deceleration assistance start condition is satisfied, start deceleration assistance for a driver's vehicle against a first deceleration-triggering object, determine whether a preset deceleration assistance termination condition is satisfied, issue a deceleration assistance termination notification to a driver of the driver's vehicle, determine whether a second deceleration-triggering object is detected ahead of the driver's vehicle, and determine whether a preset quick resumption condition is satisfied. The driving assistance apparatus is configured not to issue the deceleration assistance termination notification when the driving assistance apparatus determines that the quick resumption condition is satisfied, even in a case where the driving assistance apparatus determines that the deceleration assistance termination condition for the first deceleration-triggering object is satisfied.
US11667273B2 Motor generator control for fixed fuel source engine
A system for supplementing a fixed fuel source for an engine includes a motor-generator set connected to a mechanical load device and a controller. The motor-generator set includes a motor and a generator. The engine is configured to provide a first torque from a fixed fuel source from an independent variable flow input. The fixed fuel source is independent of the engine and set external to the engine. The mechanical load device is driven by the engine and configured to require a second torque defined by an independent flow device. The controller is configured to compare the first torque and the second torque, provide a first control signal to the motor to provide power to the engine when the second torque exceeds the first torque and provide a second control signal to the generator to draw power from the engine when the first torque exceeds the second torque.
US11667271B2 Method for activation and deactivation of a control device
In a method for activating and deactivating a control unit which can be used to control an electrically activatable assembly, the control unit is switched between a waking state, a sleep state and a deactivated state, wherein in the sleep state, the control device is disabled but can be transferred into the waking state by means of a sensor signal.
US11667270B2 Floor mounted brake pedal
The invention relates to a floor mounted brake pedal for an electrically controlled vehicle brake, comprising a first pedal lever, a second pedal lever arranged in front of the first pedal lever, a pedal platform having a stepping area and a shaft protruding from the stepping area in a forward direction, a first pedal sensor for detecting a position of the brake pedal, and a second pedal sensor for independently detecting the position of the brake pedal.
US11667267B2 Device for cleaning the optical surface of an optical sensor for a motor vehicle and associated method
The invention concerns a device (100) for cleaning the optical surface (162) of at least one optical sensor (160) for a motor vehicle. The cleaning device (100) includes a source (110) for emitting a laser beam and means for guiding the laser beam onto at least a part of the optical surface (162) of an optical sensor (160) so as to clean it.
US11667264B2 Unauthorized intrusion prevention device, unauthorized intrusion prevention method, and unauthorized intrusion prevention program
An unauthorized intrusion prevention device is provided that, in response to detection of abnormality in an electronic control device mounted in a movable body, gives an instruction for executing measures for the movable body. The unauthorized intrusion prevention device acquires first information related to a protection function of the electronic control device and second information related to a function of the electronic control device other than the protection function. The unauthorized intrusion prevention device, using the first information, performs a first determination of whether the protection function is normal. The unauthorized intrusion prevention device, using the second information, performs a second determination of whether the function other than the protection function is normal or abnormal. The unauthorized intrusion prevention device, using results of first and second determination, determines as the measures a blocking method of blocking unauthorized information in the movable object.
US11667261B2 Gas generator
A gas generator includes a housing constructed by combining and joining a plurality of shell members. One of the plurality of shell members includes a cylindrical portion and a flange portion. The cylindrical portion is provided with a plurality of gas discharge openings including gas discharge openings different in opening area from one another. The flange portion is shaped such that a distance from an axial line of the cylindrical portion to an outer edge of the flange portion is non-uniform. When a perpendicular line is drawn to the axial line from a maximum outer geometry position in the outer edge of the flange portion most distant from the axial line, a gas discharge opening arranged closest to the perpendicular line is a gas discharge opening other than a gas discharge opening largest in opening area among the plurality of gas discharge openings.
US11667258B1 Telescoping panel with reaction surface
A restraint system includes a restraint configured to deploy from an interior surface and restrain motion of an occupant and a support including a door coupled to an upper portion of the restraint. The door is configured to rotate about a pivot. The door includes a telescoping panel configured to telescopically extend from a stowed position behind the interior surface to a deployed position spaced apart from the interior surface in unison with deployment of the restraint so that the anchor reaches the deployed position after the door rotates about the pivot. The support is configured to orient the upper portion of the restraint in respect to motion of the occupant.
US11667251B2 Portable video and imaging system
A portable video and imaging system includes a camera for capturing video of an event, and a video recording device for recording the captured video of the event. The camera is housed in a first housing, the recording device is housed in a second housing, and the first and second housings are physically separate. Various embodiments provide for the system to be mounted to a user's body, an article of clothing, such as a shirt or a hat, to a vehicle, or to an ancillary component carried by the user, such as a firearm.
US11667249B2 Mount apparatus for securing an electronic device to a surface
Various embodiments of a mount apparatus are disclosed herein for securing an electronic device (such as a radar laser detector, GPS device, and/or dash camera or other electronic device used within a vehicle) to a surface such as an interior surface (e.g., windshield, dashboard) of a vehicle. In one example, the mount apparatus includes a magnet which is adapted to be coupled with a corresponding metal surface within the electronic device, so that the magnet positioned within the apparatus provides a magnetic force to aid a user in securing the mount apparatus and the electronic device to each other.
US11667242B2 Inclined type swing step and truck thereof
An inclined type swing step attached to a truck includes a step bracket mounted on a lower region of a cabin providing a driver's seat, a step for a foothold, and a step swing device composed of a hinge shaft spring and/or a press shaft spring, positioning the step inside a virtual approach angle line formed with respect to a ground from a front side of a wheel through one-side inclination in a state where the step is spaced apart from the step bracket, and generating spring elasticity acting to make the step return to an initial position after downward movement of the step. The inclined type swing step can hold shaking of the step due to driver's stepping, improve vehicle accessibility through prevention of an interference by the step, and absorb an external object impact exceeding an approach angle.
US11667236B2 Notification device
A notification device provided in a vehicle including an autonomous driving system which causes the vehicle to travel by autonomous driving and to evacuate the vehicle when a failure occurs, includes a display unit configured to display information toward an outside of the vehicle, and a display controller configured to control the display unit. The display controller causes the display unit to be turned on or flicker when a failure occurs and changes a display of the display unit in at least one of a time when an evacuation starts and a time when an evacuation is completed.
US11667234B2 Vehicle lamp system, light distribution control device, light distribution control method, vehicle determination device, and vehicle determination method
A vehicle lamp system includes a vehicle lamp, a first imaging device structured to be disposed outside a lamp room, and generate a first image, a second imaging device structured to be housed in the lamp room, and generate a second image, and a light distribution control device. The light distribution control device includes an information processor structured to acquire from an outside or generate information of a first light shielding part, and decide a second light shielding part, a control executer structured to execute light distribution control for forming a light distribution pattern including the second light shielding part, and a control regulator structured to control the vehicle lamp to form a light distribution pattern including the first light shielding part when at least one condition of a condition (i) to a condition (iv).
US11667231B2 Vehicle vision system with self-calibrating imager
A vehicular vision system includes a camera disposed at a vehicle and having a field of view exterior of the vehicle, a light source disposed at the vehicle and operable to emit light, and a control. Light emitted by the light source, when operated, illuminates a field of illumination exterior of the vehicle, with the field of view of the camera encompassing at least a portion of the field of illumination. The control, responsive to data processing by a processor of the control of image data captured by the camera, determines a change in the field of illumination provided by the light source. Responsive to the determined change in the field of illumination, the control at least one selected from the group of (i) adjusts the light source to accommodate the determined change, (ii) adjusts the camera to accommodate the determined change and (iii) generates an alert.
US11667230B2 Chassis for recreational vehicles having at least one crawl space
A recreational vehicle may include a chassis, at least one axle assembly, and a vehicle body. The vehicle body may be supported by the chassis. The axle assembly may be coupled to the chassis and may provide motive support and underbody clearance to the chassis. The chassis may include a plurality of longitudinal main rails that span at least a portion of a length of the recreational vehicle and define a length of at least one crawl space. The plurality of lateral crawl space cross members may extend between and interconnect the plurality of longitudinal main rails and define a width of the at least one crawl space. A floor of the recreational vehicle, the plurality of longitudinal main rails, and the plurality of lateral crawl space cross members may collectively define the at least one crawl space.
US11667226B2 Beverage container holding device
A beverage container holding device includes a housing member for housing a beverage container, a movable floor attached to the housing member for supporting a beverage container bottom, a movable floor biasing member for upwardly biasing the movable floor, and a movable floor locking mechanism for securing the movable floor at a predetermined height against the movable floor biasing member. The housing member has a guide groove, and the movable floor has a branch portion extending through the guide groove to an outside of the housing member, and a claw portion extending horizontally from the branch portion. The movable floor locking mechanism includes an annular member which is rotatably mounted below a bottom member, at least one column member extending upward from the annular member in parallel to the guide groove, and a lock piece integrally formed on each column member for suppressing an upper surface of the claw portion.
US11667224B2 Portable terminal holding device for vehicle
A portable terminal holding device for a vehicle includes: a table configured to be stored in a storing portion provided at one end side, in a seat width direction, of a seat cushion, and that, in a state of usage, is configured to extend from the storing portion toward another end side, in the seat width direction, of the seat cushion; and a terminal holding portion that, in the state of usage of the table, is provided at a distal end side of the table and is configured to hold a portable terminal, and that, in a stored state in which the table is stored in the storing portion, projects out from the storing portion toward the other end side in the seat width direction.
US11667223B2 Compliant edge frame bolster for suspension seating
A vehicle seat includes a support structure, a seat surface (14) and a molded polymeric frame (18). The frame has an edge region and the seat surface (14) is mounted to the frame (18) and the frame is mounted to the support structure. At least a portion of the edge region is flexible.
US11667216B2 Dynamic backward seat sliding after impact in a commercial vehicle
A safety system for a vehicle seat in a commercial vehicle operating a vehicle seat motion actuation when the commercial vehicle is colliding with an obstacle, comprising: —at least one actuator unit that comprises at least one seat actuator to move the vehicle seat from a driving position to a safety position—at least one control unit connected to said actuator unit to control the at least one seat actuator—at least one proximity sensor connected to said control unit and configured to detect an obstacle before the commercial vehicle collides it characterized in that the control unit is provided with a calculator device retrieving specific data (Dw, Dw′, Ds, Do) to determine the requested seat's motion speed profile and the requested seat's motion triggering moment to control, upon receiving an imminent and unavoidable collision alert signal from the proximity sensor, the at least one seat actuator to move the vehicle seat to the safety position.
US11667213B2 Electromobility system for a vehicle
An electromobility system for a vehicle comprising a primary sub-system including at least a first battery pack arrangement to power an electric machine for propelling the vehicle, a secondary sub-system being a high voltage sub-system and including at least a second battery pack arrangement to power an auxiliary equipment, and a DC/DC-converter galvanically separating the primary sub-system from the secondary sub-system. The system, in a first state, powers the electric machine by the first battery pack arrangement of the primary sub-system independently of the secondary sub-system, and powers the auxiliary equipment by the second battery pack arrangement in the secondary sub-system independently of the primary sub-system, and in a second state, powers the auxiliary equipment by the second battery pack arrangement of the secondary sub-system and, via the DC/DC-converter, the first battery pack arrangement of the primary sub-system.
US11667199B2 Motor vehicle with an electric motor, in particular a hybrid or electric vehicle
An interruption device is provided in a motor vehicle to interrupt a signal line in an emergency operating state. The interruption device includes a fuse and a resistor in the signal line and first and second switches. The fuse is arranged upstream of the resistor in a signal line direction extending from a low-voltage on-board electrical system to a high-voltage on-board electrical system. The first switch is provided in a first electric line connecting the signal line to ground at a connection point downstream of the resistor, and the second switch is provided in a second electric line which connects the signal line to ground at a connection point between the fuse and the resistor. The first and second switches are open during the normal operation of the motor vehicle and are closed in response to the control signal to interrupt the signal line by separating the fuse.
US11667193B2 Method of controlling a tandem axle assembly
Methods of controlling a tandem axle assembly in a vehicle, the tandem axle assembly including an inter-axle differential (IAD), one or more side gears, and a front tandem axle assembly having a pair of front tandem axle half shafts selectively connected to a pair of front tandem axle wheel hub assemblies. When a determined speed of the vehicle is greater or equal to a predetermined speed, the IAD may be locked, the tandem axle wheel hub assemblies may be disconnected from their respective tandem axle shafts, and/or the IAD may be moved out of engagement with the one or more side gears. When a determined speed of the vehicle is less than a predetermined speed, the IAD may be unlocked, the tandem axle wheel hub assemblies may be connected to their respective tandem axle shafts, and/or the IAD may be engaged with the one or more side gears.
US11667190B2 Work vehicle
A work vehicle includes a power transmission unit having a differential device for transmitting power to left and right axles and a power transmission mechanism for transmitting power to the differential device, and a transmission shaft for transmitting power to the power transmission unit. The power transmission mechanism includes a first gear mechanism to which power from the transmission shaft is transmitted and a second gear mechanism for transmitting power from the first gear mechanism to the differential device.
US11667189B1 Electric drive axle with a gearbox and gearbox operating method
Methods and systems for an electric drive axle are provided. An electric drive axle, in one example, includes an electric machine rotationally coupled to a gearbox which includes a higher range planetary gear set coupled to a lower range planetary gear set via a clutch. The clutch is configured to selectively rotationally couple an input gear to a sun gear in each of the higher range planetary gear set and the lower range planetary gear set in different positions or selectively rotationally couple a carrier in the higher range planetary gear set to a carrier and a sun gear in the lower range planetary gear set in different positions.
US11667188B2 Operating fluid container having a compensation container for compensating for pressure fluctuations in the operating fluid container
An operating fluid container for a motor vehicle for accommodating an operating fluid. The operating fluid container has a compensation container that is at least indirectly fluidically connected to the atmosphere (ATM). The operating fluid container has the following features: the compensation container is situated within the operating fluid container in such a way that an outer surface of a compensation container upper shell is situated opposite from an inner surface of an operating fluid container upper shell; in the event of positive pressure in the operating fluid container relative to the atmosphere, a compensation container volume decreases; and in the event of negative pressure in the operating fluid container relative to the atmosphere, the compensation container volume increases. The operating fluid container is characterized in that the compensation container upper shell opposite from the operating fluid container upper shell has a shape, at least in sections, that is complementary to the operating fluid container upper shell.
US11667185B2 Device for ventilating a vehicle
A ventilating device for ventilating a vehicle includes a frame defining an opening and a closing device including at least one closing flap extending in a general direction in the opening. The closing device is movable between open and closed positions such that a passage surface for the air through the ventilating device is smaller than the passage surface for the air when the closing device is in the open position. The flap is movable between open and closed positions and is mounted pivotably on the frame in order to pivot between the open and closed positions. The closing device includes a guide system for guiding the flap, which is arranged between two ends of the flap and includes a guide slot and a pin moving in the guide slot between the open and closed positions.
US11667184B2 Hybrid electric vehicle
An hybrid electric vehicle (HEV) drives front wheels by a motor-generator via drive shafts by use of electricity generated by an internal combustion engine (ICE). A lower portion of the internal combustion engine is locate on a front side of a lower portion of the motor-generator in the vehicle body with being distanced therefrom. A steering gearbox is placed between the internal combustion engine and the motor-generator and located on a front side of the drive shafts. According to this configuration, driving stability, steering feeling, and noise and vibration can be balanced at a high level.
US11667181B2 Lawn mower and battery package assembly thereof
The invention provides a mower, which comprises a battery package assembly and a frame for bearing the battery package assembly; the battery package assembly comprises a battery package and a fixing plate, the battery package is fixed on the fixing plate, a plurality of first pulleys are arranged at the bottom of the fixing plate, and the first pulleys are distributed along the installation direction of the battery package assembly. The frame comprises a supporting surface, and the first pulleys are supported on the supporting surface. The battery package assembly of the lawn mower moves on the supporting surface in a rolling mode, generated friction force is small, and convenience and labor saving can be achieved for the mounting and dismounting processes of the battery package assembly.
US11667175B2 Interior panel including capacitive change detection for an interior of a vehicle and a method for making the same
Interior panels for interiors of vehicles, vehicles, and methods for making interior panels for interiors of vehicles are provided. In one example, the interior panel includes an outer covering having a first surface. A second surface is disposed opposite the first surface. The second surface has a pattern formed therein that is hidden from the first surface. A light source is operative to generate light and is disposed adjacent to the second surface generally aligned with the pattern. When the light source generates light, an illuminated pattern corresponding to the pattern is visible on the first surface. A capacitive sensor is configured to generate a capacitance change signal in response to change in capacitance of the capacitive sensor. A controller is in communication with the capacitive sensor to receive the capacitance change signal and is configured to generate a command signal in response to the capacitance change signal.
US11667174B2 Smart electric refrigeration system for vehicles
A smart electric temperature-controlled system connected to a vehicle, such as a vehicle-transported refrigeration system, includes a power management system and an energy storage module. The power management system and energy storage module can manage power delivered to the temperature-controlled system components by monitoring temperatures and voltages (and possibly other factors) and by delivering power as a function of the things monitored. In a typical implementation the power management system and an energy storage module can supply power to a vehicle-transported refrigeration system when the vehicle is stopped and/or power from the vehicle electrical system is electrically isolated or otherwise unavailable.
US11667163B2 Anti-rattle hitch tightener
A hitch tightener is used around the lip of a hitch receiver tube and a shank inserted into the hitch receiver tube. The hitch tightener has a U-bolt with two threaded legs, and a crossbar with throughholes for the legs of the U-bolt, positioned so the crossbar and the U-bolt encircle the shank and the receiver tube lip. A standard threaded nut holds the crossbar onto one of the legs, and a cam lock lever is pivotally attached on the other leg by a threaded trunnion nut. When the cam lock lever is pivoted from its opened position to its closed position, it moves the crossbar toward the connecting portion of the clamp component, tightening the hitch tightener around shank and lip.
US11667159B2 Tread for a pneumatic tire and a pneumatic tire
Tread for a pneumatic tyre comprising a sipe having a sipe extension (L) and a sipe depth (P) along a direction of wear (U), wherein said sipe has at least two sections (S1, S2) along said direction of wear (U) having respective differentiated conformations, such that an intersection profile (P1, P2) between the sipe and a surface (T1, T2) parallel to the contact surface of the tread is different for each of said at least two sections (S1, S2), wherein at least one surface section (S1) of said at least two sections (S1, S2) has a depth (PS) that is variable along said sipe extension (L), said two sections (S1, S2) being connected by a transition section (S3) defining a transition line (TL) between the respective sections (S1, S2), said variable depth (PS) of said surface section, presenting a maximum depth (PSMAX) and a minimum depth (PSMIN), and wherein the surface section (SI) has a twisted configuration.
US11667157B2 Tire
In a tire, a tread includes a cap layer forming a part of the outer surface of the tire, an intermediate layer disposed inwardly of the cap layer in the radial direction, and a base layer disposed inwardly of the intermediate layer in the radial direction. A loss tangent of the intermediate layer at 30° C. is less than a loss tangent of the cap layer at 30° C., and a loss tangent of the base layer at 30° C. is less than the loss tangent of the intermediate layer at 30° C. An outer end of the cap layer is disposed outwardly of an outer end of the base layer in the axial direction. In the radial direction, a position of the outer end of the cap layer coincides with a position of the outer end of the base layer, or the outer end of the cap layer is disposed inwardly of the outer end of the base layer.
US11667153B2 Automated removal and replacement of vehicle wheels and tires
Systems, methods and apparatus for automated vehicle wheel removal and replacement are provided. One system includes a computer system with applications for scheduling the replacement of tires for the vehicle. An electronically controlled lift device and robotic apparatus is configured for interaction with the computer system. The lift device mechanically adjusts arms for placement on lift points of vehicles. The robotic apparatus detects positioning of lug nut configuration for a wheel, removes lug nuts, and then removes the wheel from the wheel hub with gripping arms. The wheel and tire are then handed off to a separate tire changing machine. When a new tire is replaced the robotic apparatus then mounts the wheel to the original wheel hub, and then secures the lug nuts to the lug nut bolts.
US11667149B2 Wheel center caps and related methods
Wheel center caps and related methods are disclosed herein. An example wheel center cap includes a body, a first protrusion extending radially outward from the body, and a second protrusion extending radially outward from the body. The first and second protrusions define a gap therebetween. The example wheel center cap includes a leg disposed in the gap and coupled to the body. The leg includes a foot. The foot extends radially outward relative to the body. The foot includes a chamfered face facing away from the body.
US11667148B2 Rim reinforcement fitting
A vehicle wheel having a rim, a hub, a plurality of spokes with at least one of the spokes having a first portion connected the rim and a second portion connected to the hub. The rim includes a spoke bed wall with a radially outboard surface and a spoke hole having a radially outboard entrance and perimeter edge. The spoke extends through the spoke hole and is engaged to the spoke bed wall by an overlie engagement at a bearing interface between a bearing surface of the spoke and the radially outboard surface to limit longitudinally inward displacement between the spoke and spoke bed wall. At least a portion of the bearing interface is laterally outwardly spaced from the first perimeter edge by a lateral distance of at least 0.7 millimeters.
US11667144B2 Bookmarking device
A device including a bookmarker for bookmarking pages of a book, the bookmarker having a first and a second end. A locking mechanism locks the first and second ends. A first indicator is operable for indicating a desired portion of the page of the book. A second indicator is operable for indicating an unusual or interesting word on the page. A marker is operable for marking an index page to the corresponding page marked by the front portion of physical bookmark device or a solution page corresponding to a problem containing page marked by the front portion of the bookmarker. A counter for counting down or counting up from a predetermined starting value to a user-set or preset timer value. A motion sensor for determining when a user is reading or otherwise engaged with the page. An alarm for alerting or notifying of the preset timer value being reached.
US11667137B2 Medium transport apparatus and processing apparatus
A medium transport apparatus includes a body portion, an inversion unit, and an extension unit. The body portion has a second manual feed path for a sheet material. The inversion unit is configured to be mounted on and separated from the body portion, covers the second manual feed path when the attachment/detachment portion is mounted the body portion, and exposes a portion of the second manual feed path when the attachment/detachment portion is separated from the body portion. The extension unit is configured to be attached to and detached from the attachment/detachment portion. The extension unit extends, in a state in which the inversion unit is separated, the second manual feed path in a transport direction of the sheet material by being detached from the inversion unit and attached to the body portion.
US11667124B2 Print liquid supply
A print liquid supply apparatus or interface structure to be connected to a print system comprises a liquid channel, liquid interface and integrated circuit contact pads.
US11667121B2 Maintenance device, liquid discharge apparatus, maintenance method, and non-transitory recording medium
A maintenance device includes a plurality of heads that discharges liquid for printing. A cleaner selectively cleans the heads. A cleaning controller controls the cleaner. A determiner determines a cleaning time when the cleaner cleans one of the heads. An interruption-resumption controller controls the heads to interrupt printing at the cleaning time and resume printing when the cleaner finishes cleaning the one of the heads. The cleaning controller controls the cleaner to clean the one of the heads whenever the interruption-resumption controller controls the heads to interrupt printing at the cleaning time.
US11667120B2 Liquid discharge apparatus
A liquid discharge apparatus includes a liquid discharger, a discharge receptacle, and circuitry. The liquid discharger includes a nozzle configured to discharge liquid. The discharge receptacle is configured to receive the liquid discharged from the liquid discharger. The circuitry is configured to control a flushing operation of the liquid discharger. The circuitry is configured to cause the liquid discharger to perform flushing to the discharge receptacle and a sheet to which the liquid is applied, with a first flushing amount and a second flushing amount different from the first flushing amount, respectively.
US11667118B2 Liquid discharging head
There is provided a liquid discharging head including: a plurality of supply manifolds configured to receive a liquid to be discharged from a plurality of nozzles and provided side by side with each other; a supply integration channel arranged on a first side in a longitudinal direction of the supply manifolds; a first connecting channel connecting the supply integration channel and a first supply manifold of the supply manifolds; and a second connecting channel connecting the supply integration channel and a second supply manifold, of the supply manifolds, being adjacent to the first supply manifold in a short direction of the first supply manifold. An outlet of the first connecting channel is arranged on the first side in the longitudinal direction of the supply manifolds; and an outlet of the second connecting channel is arranged on a second side in the longitudinal direction of the supply manifolds.
US11667117B2 Electronic device, liquid discharge head, liquid discharge device, liquid discharge apparatus, and electronic apparatus
An electronic device includes a switching element, a first common-electrode wiring, at least a part of the first common-electrode wiring being covered with the switching element, a plurality of second common-electrode wirings branched from the part of the first common-electrode wiring covered with the switching element, a plurality of individual power-output terminals arranged in a row in the switching element, and a plurality of individual-electrode wirings arranged in a row, the plurality of individual-electrode wirings being connected to the plurality of individual power-output terminals, respectively. Each of the plurality of second common-electrode wirings is disposed between the plurality of individual-electrode wirings.
US11667116B2 Print component having fluidic actuating structures with different fluidic architectures
A print component includes an array of fluidic actuation structures including a first column of fluidic actuating structures addressable by a set of actuation addresses, each fluidic actuating structure having a different one of the actuation addresses and having a fluidic architecture type, and a second column of fluidic actuating structures addressable by the set of actuation addresses. Each fluidic actuating structure of the second column has a different one of the actuation addresses and has a same fluidic architecture type as the fluidic actuating structure of the first column having the same address. An address bus communicates the set of addresses to the array of fluidic actuating structures, and a fire signal line communicates a plurality of fire pulse signal types to the array of fluidic actuating structures, the fire pulse signal type depending on the actuation address on the address bus.
US11667115B2 Digital halftoning with spiral dots
A halftone raster image suitable for rendering a continuous-tone image includes a plurality of spiral dots. The spiral dots include image pixels arranged as a first arc or as a plurality of arcs which together represent a first spiral, and non-image pixels arranged as a second arc or as a plurality of arcs which together represent a second spiral. The spiral dots enable a controlled spreading of the ink within the dot, resulting in a higher image quality, ink saving, and faster drying.
US11667113B2 Badges and methods for making badges
A method for making a badge includes laminating a printed substrate with a back side laminate sheet and a front side laminate sheet and disposing a barrier sheet between at least one of the back side laminate sheet and the printed substrate and the front side laminate sheet and the printed substrate. And a side loading pocket section is formed between at least one of the back side laminate sheet and the printed substrate and the front side laminate sheet and the printed substrate.
US11667111B2 Method for forming flexible cover lens films
Display modules typically incorporate a transparent hard material such as glass on the outside of the module in order to better protect the display stack from scratches, dents, and other mechanical deformations. However, as displays move to novel form factors such as bendable, foldable, and reliable display modules, these transparent hard materials (e.g., glass) may not be used due to their limited flexibility. Therefore, it is desirable that replacement materials be sufficiently flexible while maintaining the desirable optical (e.g., >90% transmission and low yellow index) and mechanical properties (e.g., pencil hardness>H) that comparable glass hard materials offer.
US11667108B2 Laminated steel plate, manufacturing method therefor, and sheet to be used therefor
An embodiment relates to a sheet comprising an acrylic resin layer and a fluorinated polymer resin layer directly formed on one surface of the acrylic resin layer; a laminated steel plate comprising the sheet; and a manufacturing method therefor.
US11667099B2 System for creating a relief pattern on a substrate
A die and counter die system for impressing a relief pattern onto a substrate, including a male die film and at least one female die. The female die includes a female-die contact surface including at least one cavity defining the relief pattern. The male die film includes a flexible male-die contact surface which is featureless in a region thereof opposing the relief pattern on the at least one female die. The system further includes a compression mechanism adapted, when the substrate is disposed between the male die contact surface and the female die contact surface, to move the male die film and the at least one female die towards one another so as to impress the relief pattern on the substrate.
US11667093B2 Method for manufacturing one-piece corrective eyewear
A method for manufacturing one-piece corrective eyewear. The method includes a first step wherein an item with essentially flat blank shape is formed by a 3D-printing process. The item encompasses two lens portions, a bridge portion, and two temple portions; or the two lens portions and the bridge portion. The method includes a second step wherein the item is deformed into a wearable shape. During the first step a frame portion surrounding the lens portions is formed as part of the blank shape.
US11667092B2 Sheet metal member forming method and sheet metal member forming device
A sheet metal member forming method comprises placing a fiber bundle of a predetermined length, via a thermosetting resin, in a predetermined position on a surface of a sheet metal member, forming a coating film on at least a part of the sheet metal member after the placing of the fiber bundle, and while heating and drying the coating film, heat-curing the thermosetting resin to bond the fiber bundle to the sheet metal member.
US11667088B2 Welding device and welding method
A welding device includes a pair of pressure rollers for pressurizing a web and a strip member, a feed device configured to intermittently or continuously feed the web and the strip member through the pair of pressure rollers, and the laser device configured to irradiate the web or the strip member with a laser beam at a position upstream of the pair of pressure rollers. The welding device may include a movement device configured to move the pair of pressure rollers upstream with respect to the web and the strip member during pause or stop of feed. Alternatively, the feed device may pause or stop the web and the strip member after retracting the web and the strip member by a certain length.
US11667087B2 Distance member for connecting wind turbine blade shear webs
The present invention relates to a wind turbine blade and a method for its manufacture. A lower shell part and an upper shell part are provided, each shell part having a leading edge and a trailing edge. A first shear web and a second shear web for connecting an inner surface of the lower shell part with an inner surface of the upper shell part are provided. The first shear web and the second shear web are connected by a first distance member in a chordwise direction. The first distance member is arranged for accommodating a variable chordwise distance between said first shear web and said second shear web. The first shear web and the second shear web are placed in the lower shell part and the upper shell part is mounted.
US11667082B2 Apparatus and method for manufacturing a three-dimensional object
An apparatus for manufacturing a three-dimensional object by a layer-by-layer solidification of building material at the points corresponding to the cross-section of the object to be manufactured in a respective layer. The apparatus includes a process chamber in which the object is to be built up layer by layer by selectively solidifying layers of a building material in a build area, a gas supply device, and a recirculating air filter device, wherein the apparatus comprises a pressure stabilization device configured to keep the pressure in the process chamber substantially constant.
US11667080B2 System for obtaining a photopolymerized prepolymer
A system for obtaining a photopolymerized prepolymer for use as a component of a material suitable for manufacturing buildings or building components by 3D printing processes. The system contains a flexible closed loop conveyor stretched between a precursor loading station and a prepolymerization material receiver from which the product is unloaded to a construction 3D printing machine. The conveyor carries a plurality of flexible trays capable of looping around the pulleys of the closed loop conveyor. The trays are shallow troughs that have open tops and carry dosed portions of the precursor, which is photopolymerized on its way from the loading station to the unloading station by sequentially passing under light sources of two photopolymerization stations. When the trays pass through the unloading position, they are turned upside-down and allow the precured material to fall into a receiver.
US11667079B2 Stereolithography apparatus equipped with shutter cooling channel
A stereolitography apparatus comprises a fixed vat (401) or a holder for receiving a removable vat for holding resin during stereolithographic 3D printing, and a radiation source (501) for generating radiation capable of polymerizing portions of said resin in said vat. (401). The apparatus comprises a shutter (502) between said radiation source (501) and said vat (401) for allowing only selected portions of the generated radiation to reach said resin, and a cooling channel (503) between said radiation source (501) and said shutter (502). The apparatus comprises a blower (504) configured to force coolant gas through said cooling channel (503).
US11667077B2 Conveying installation and tool head for an additive manufacturing machine, and additive manufacturing machine
For increasing the speed in 3D printing, for avoiding the conveying elements slipping from the conveyed semi-finished product, and for improving the transmission of force from the conveying elements to the semi-finished products to be conveyed, a conveying installation is provided for an additive manufacturing machine. The conveying installation for conveying a semi-finished product comprises a longitudinal conveying mechanism which by means of a periodic movement of at least one conveying element conveys the semi-finished product along a conveying direction which is parallel to the semi-finished product longitudinal axis. The conveying element when moving in the conveying direction acquires the semi-finished product, and when moving counter to the conveying direction is released from the semi-finished product. This results in a movement of the semi-finished product in the conveying direction.
US11667062B2 Nanostructures from laser-ablated nanohole templates
Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate.
US11667061B2 Method of forming leveraged poromeric polishing pad
The invention provides a method of forming porous polyurethane polishing pad that includes feeding liquid polyurethane onto a web sheet with a doctor blade while back tensioning the web. Coagulating liquid polyurethane onto the web sheet forms a two-layer substrate. The two-layer substrate has a porous matrix wherein the porous matrix has large pores extending upward from a base surface and open to an upper surface. Spring-arm sections connect lower and upper sections of the large pores.
US11667060B2 Hydraulic advancement/postponement assembly
A hydraulic advancement/postponement assembly is operably coupled to a first ejector plate and to a second ejector plate. The hydraulic advancement/postponement assembly includes a first hydraulic cylinder having a first housing defining a first volume and a first piston, the first housing connected to the first ejector plate and the first piston connected to a fixed element. The hydraulic advancement/postponement assembly includes a second hydraulic cylinder disposed in fluid communication with the first hydraulic cylinder, the second hydraulic cylinder having a second housing defining a second volume and a second piston, the second housing connected to the first ejector plate and a second piston connected to the second ejector plate.
US11667058B2 Utilization of fine mineral matter in the conversion of non-biodegradable plastic and in remediation of soils polluted with non-biodegradable plastic
The disclosed embodiments describe a novel approach to the utilization of the fine mineral matter derived from coal and/or coal refuse (a by-product of coal refining) to convert a non-biodegradable plastic into a biodegradable plastic. The fine mineral matter could also be based on volcanic basalt, glacial rock dust deposits, iron potassium silicate and other sea shore mined deposits. The conversion of the non-biodegradable plastic into biodegradable plastic in soil further increases nutrients availability in soil with the transition metals released as a result of biodegradation of the biodegradable plastic.
US11667057B2 Manufacture of filament material
A method utilizes waste product in manufacturing, such as manufacture of filaments or micro-pellets for use in manufacturing applications such as additive manufacturing, extrusion, injection molding, blow molding and other applications.
US11667055B2 Method and apparatus for producing particles, particles, composition, particles dispersion liquid, and method for producing the particles dispersion liquid
A method for producing particles, the method including: depolymerizing a resin to obtain a depolymerized product; contacting the depolymerized product obtained in the depolymerizing with a first compressive fluid to obtain a melted product; and jetting the melted product obtained in the contacting to granulate the particles.
US11667054B2 Wide speed range concrete monitoring calibration
A method and system for concrete monitoring calibration using truck-mounted mixer drum jump speed data selectively assimilated from previous deliveries. The method involves measuring energy at a first drum speed and a second drum speed. Slump is calculated using low speed energy/speed/slump curve data, or pre-stored equation wherein slump is derived as a function of slope of the line. The energy, speed, slump relationship in the provided concrete is compared to at least two pre-stored data curves across drum speed ranges of 15 0.5 RPM-6 RPM and 6 RPM-20 RPM, to ascertain whether the provided concrete matches any of the stored curve data; either activating the monitoring system for all drum speed ranges where a match is confirmed or allowing the monitoring system to calculate slump only at low drum speeds.
US11667053B2 Support material for energy-pulse-induced transfer printing
The invention relates to a material for use as support material for energy-pulse-induced transfer printing, which contains (a) at least one energy transformation component, (b) at least one volume expansion component and (c) at least one binder and which has a viscosity at 25° C. of from 0.2 Pas to 1000 Pas and a surface tension at 25° C. of from 20 to 150 mN/m. The invention furthermore relates to a process for producing three-dimensional objects using the support material.
US11667051B2 Punch assemblies and toolless systems thereof for tip retention and release
Punch assembly that enable selective securement and release of punch tips to a punch body (or holder) of the assemblies, wherein various retain/release systems can be used with the punch body, specifically relative to triggering mechanisms of such systems and their functioning and use with ancillary components relative to securing and releasing the punch tip, without adversely affecting long-term efficiency and effectiveness of the assemblies.
US11667044B2 Tool having a detectable wireless marker or tag
A tool having a detectable wireless marker or tag is provided. The tool has a working portion with a projection or tang by which the working portion of the tool is held, a wireless tag located on, but insulated from the tang, and a handle disposed over and encompassing the projection or tang and the wireless tag. In an exemplary embodiment, the wireless tag is insulated from the tang using a housing assembly made up of an inner holder, an outer holder, and the detectable wireless tag positioned between the inner and outer holders. The invention allows for the use of fragile markers or tags, which are protected by the housing assembly from temperatures and pressures used during, for example, tool handle manufacturing processes. Also provided is a method for providing a tool with a detectable wireless tag, and a method for tracking and tracing tools used within a packaging facility.
US11667042B2 Retainer apparatus for movement of articles
A retainer apparatus configured to releasably retain an article, comprising a face plate member each having a front face, a plurality of vacuum cups and a plurality of support pins each extending distally relative to the front face, respectively, wherein the vacuum cups and the support pins are laterally spaced from one another, wherein the plurality of vacuum cups retain the article to the retainer apparatus in a presence of vacuum, wherein the plurality of support pins are extendable/retractable relative to the face plate member, wherein each of the support pins have a longitudinal axis, respectively, and are configured to contact the article to support the article against movement along the longitudinal axis and support the article against movement transverse to the longitudinal axis, and a locking mechanism configured to inhibit the support pins from being retractable and extendable when the locking mechanism is engaged.
US11667041B2 Robot cleaner, station and cleaning system
A cleaning system is provided. The cleaning system includes a robot cleaner and a station. The robot cleaner includes a pad fixing part on which a cleaning pad is detachably mounted, a lifter to lift a part of the robot cleaner at which the pad fixing part is positioned, and a pad detacher to detach the cleaning pad mounted on the pad fixing part. The station includes a pad storage box in which a cleaning pad that is to be provided to the robot cleaner is stored, a pad coupling part on which a cleaning pad that is to be coupled to the robot cleaner is rested, and a pad supplier to supply the cleaning pad stored in the pad storage box to the pad coupling part.
US11667040B2 End effector
An end effector for laying down fibers on a laying mold, the end effector having at least one bobbin arrangement of a system type, the system type being defined by virtue of the fact that the bobbin arrangement has a first bobbin for providing a first fiber strand and a second bobbin for providing a second fiber strand, the rotational axes of the first and the second bobbin being arranged at an angle with respect to one another, the first fiber strand and the second fiber strand being merged over a deflection unit and being guided from a corner region of the end effector jointly into a center region of the end effector and further to a pressure roller.
US11667037B2 Robot system with hand-guiding function
A robot system with a hand-guiding function is disclosed. The robot system selects the hand-guiding function or non-hand-guiding function of an enable device by a mode option mechanism during the operation of a teach mode or an automatic mode. When selecting the hand-guiding function, the enable device has both the enabling and the hand-guiding function to easily hand-guiding the robot to operate.
US11667035B2 Path-modifying control system managing robot singularities
A controller for robot arms and the like having mechanical singularities identities paths near the singularities and modifies those paths to avoid excessive joint movement according to a minimization of tool orientation deviation to produce alternative paths that minimize changes in the tool orientation such as can affect application such as welding, sealant application, coating and the like.
US11667034B2 Computerized system and method using different image views to find grasp locations and trajectories for robotic pick up
Computerized system and method are provided. A robotic manipulator (12) is arranged to grasp objects (20). A gripper (16) is attached to robotic manipulator (12), which includes an imaging sensor (14). During motion of robotic manipulator (12), imaging sensor (14) is arranged to capture images providing different views of objects in the environment of the robotic manipulator. A processor (18) is configured to find, based on the different views, candidate grasp locations and trajectories to perform a grasp of a respective object in the environment of the robotic manipulator. Processor (18) is configured to calculate respective values indicative of grasp quality for the candidate grasp locations, and, based on the calculated respective values indicative of grasp quality for the candidate grasp locations, processor (18) is configured to select a grasp location likely to result in a successful grasp of the respective object.
US11667032B2 Processing device
A processing device with a processing head including a processing unit designed as a tool and/or applicator unit, in particular a printer unit, and a first positioning device for moving the processing head in order to position the processing unit with a first accuracy at a specified processing position. The processing head has a second positioning device and the processing device is adapted to position the processing unit at the specified processing position with a second accuracy using the second positioning device, the second accuracy being higher than the first accuracy, so that the lower accuracy of the first positioning device is compensated for by the positioning with the second positioning device.
US11667029B1 Three-axis end-limiting tool placement structure
A three-axis end-limiting tool placement structure includes a basic face, a first-end three-axis limiting portion, a second-end X-axis limiting portion, and a sliding Z-axis limiting piece at the second end. The first end of the three-axis limiting part includes one end abutting wall, two lateral limiting walls and a pressing edge, so that the first end of the tool placement bar reaches the X, Y, Z axial limiting state. The X-axis limiting portion is used to limit at least the X-axis of the second end of the tool placement bar. The sliding Z-axis limiting piece at the second end includes a track set and a sliding cover, and the sliding cover has a release and locking positions. When the sliding cover is in locked position, the cover is blocked on the top surface of the second end of the tool placement bar, thereby forming the Z-axis in limiting state.
US11667026B2 Battery pack with lanyard receiver and tether with quick attachment
A battery tether system for tethering a power tool battery is provided. The battery may include a tether receiver as an integral component of the battery or the battery may be retrofit with a sleeve or bumper including a tether receiver. The sleeve may include a clasp to overlay the retrofit battery and ensure that the tether receptacle remains coupled to the battery. The tether receiver may connect to the tool receiver and provide an electrical connection to the tool and a tether receiver for the battery. The battery system may include tether keys configured to be inserted into a slot and slide into a locking pocket of the sleeve or bumper.
US11667025B2 Tool device
A tool device comprises a first module and a second module that can be detached from the first module, the first module having a receptacle and the second module having an insertion part that can be inserted in the receptacle along an insertion axis. The insertion part can be rotated in the receptacle about the insertion axis between a locked position and an enabled position, the receptacle having a first projection and the insertion part having a second projection. In the locked position, the second projection engages behind the first projection in the direction of the insertion axis, and in the enabled position, the first projection enables the second projection to pass in the direction of the insertion axis, the receptacle preventing an activation of the tool device in an initial position and allowing activation of the tool device in a pressed-on position.
US11667023B2 Hybrid cordless cap tool
A construction tool and method for use for administering a fastener and an associated cap to secure fabrics, paper, sheets, and/or panels to a substrate is provided. The tool can be a hybrid tool that utilizes a) energy stored in a spring, the energy harvested upon engagement of the tool with a surface, to move a cap and/or a fastener to an advancement station, and b) energy stored in a power source, such as a battery, to advance the fastener through the cap and apply the fastener/cap combination to a substrate. The hybrid tool can utilize both energy harvested from mechanical motion and energy stored in an onboard power source to function. A related method of using the tool is provided.
US11667021B2 Inertial fan for power tool
A power tool includes a motor having a motor shaft that rotates about a motor axis in a first rotational direction. The power tool also includes a fan assembly attachable to the motor shaft for rotation in the first rotational direction. The fan assembly includes a fan body, a bearing having a race that rotates with the fan body, and a flywheel rotatably affixed to the fan body. The race is freely rotatable relative to the motor shaft in the first rotational direction, and fixed against rotation relative to the motor shaft in a second rotational direction opposite the first rotational direction. The flywheel has a central portion that defines a central bore, and the race is received into the central bore and rotatably affixed to the flywheel.
US11667019B2 Driving mechanism for fastener driving machine
A driving mechanism for fastener driving machine, including a rotatable crank; a driving rack element rotatably installed on the crank, which comprises an engaging element, a support element and a driving rack; at least one fixed guide element. The support element and/or engaging element can move along the set trajectory. The present invention has a simple structure, a few parts and stable operation. When the crank rotates, the motion trajectory of the engaging element is straight or approximately O°, so as to reduce the kinetic friction force of load to the maximum extent, preventing wear problem, and guaranteeing constant direction of thrust on the impact unit in the course of compressed energy storage and low eccentric load in late stage, the quick release of driving mechanism is implemented, the operational stability and smoothness of impact unit are guaranteed, the work quality is upgraded.
US11667016B2 Auto window belt molding removal tool
The auto window belt molding removal tool is for removing the auto window belt molding from the auto body door panel. This thin strong tool has a thin handle at one end of the shaft, at the other end is a hook with a unique flat angle. Easily inserted between the auto window and the auto window belt molding, with a twist to align the unique flat angle to get purchase on the auto window belt molding and detach it from the retainer.
US11667014B2 Jig for cover window
A jig for a cover window may include a lower jig and an upper jig on the lower jig. The lower jig may include a mounting portion, on which a cover window is configured to be disposed, and an exhausting portion adjacent to the mounting portion. The upper jig may include a cover unit, in which an opening exposing the mounting portion is defined, and a sidewall portion, coupled to the cover unit and enclosing the lower jig. The cover unit may be spaced apart from and overlapped with the exhausting portion.
US11667013B2 Manual hydraulic multi-functional extra-high-voltage insulating gear gripper pliers stick for live-wire work and indirect live-wire construction method using pliers stick
The present invention relates to a manual hydraulic multi-functional extra-high-voltage insulating gear gripper pliers stick for live-wire work and the pliers stick and, more specifically, to a manual hydraulic multi-functional extra-high-voltage insulating gear gripper pliers stick for live-wire work and an indirect live-wire construction method using the pliers stick, which: allow components or the like, which are installed on and removed from an electric pole in order to perform electric wire-stringing work or fix electric wires, to be remotely constructed by means of the indirect live-wire work while maintaining a safe distance from live wires when constructing power distribution equipment in an extra-high-voltage live-wire state; ensure safety by eliminating risks due to instability during work, said instability occurring due to the intensity of the labor and the physical limitations of the workers; and bring about improvements in utilization efficiency.
US11667009B2 Bonded abrasive article and method of making the same
An abrasive article can include a body including a bond material, abrasive particles, and a plurality of pores, wherein the bond material can comprise a vitreous material. In one embodiment, an average particle size of the abrasive particles can be between 0.1 microns to 5 microns, and a porosity of the body may be between 40 vol % to 70 vol %, wherein the porosity may define an average pore size (D50) of at least 0.1 microns and not greater than 5 microns.
US11667008B2 Substrate processing apparatus and substrate processing method
A substrate processing apparatus which reliably prevents a cleaning liquid containing foreign particles from falling from a polishing head onto a substrate is disclosed. The substrate processing apparatus includes a rotating and holding mechanism, a polishing head, and a head cleaning device configured to supply the cleaning liquid to the polishing head to clean the polishing head during polishing and/or after polishing of the substrate.
US11667007B2 Polishing apparatus and polishing method
A polishing table holds a polishing pad. A top ring holds a semiconductor wafer. A swing arm holds the top ring. The swing arm swings around a swing center on the swing arm during polishing. An optical sensor is disposed on the polishing table and measures an optical characteristic changeable in accordance with a variation in film thickness of the semiconductor wafer. A fluid supply control apparatus determines a distance from an axis of rotation to the optical sensor when the semiconductor wafer is rotated by the top ring. An end point detection section detects a polishing end point indicating an end of polishing based on the optical characteristic measured by the optical sensor and the determined distance.
US11667003B2 Processing apparatus
A wafer held on a delivery pad is lifted from a holding surface, and when a lower surface of the wafer has been spaced in its entirety from the holding surface, an air flow rate regulating valve is opened to eject air from the holding surface. As the distance between the holding surface and the wafer spaced from the holding surface increases by lifting of a delivery unit, the degree of opening of the air flow rate regulating valve is adjusted to increase a flow rate of air from the holding surface, thereby spacing the wafer from the holding surface in a short period of time without rupturing the wafer.
US11667001B2 Ninety degree auto changer spindle mounting assembly
A novel mounting assembly used with an air spindle is described. The mounting assembly includes an insertable top portion for inserting into a mounting collar and to be rotatable therein, the insertable top portion formed with an upper disk shape with a first diameter and a lower disk shape with a second diameter and adjacent to the upper disk shape, an outer circumference of the upper disk shape having a groove formed therein, and the upper disk shape and the lower disk shape having a passage axially formed therethrough perpendicular to the groove. The mounting assembly further includes a sleeve disposed below the insertable top portion, the sleeve defining an opening with a sidewall which is perpendicular to the insertable top portion, the opening sized to hold a spindle, a port inside a wall of the sleeve defining the opening providing fluid communications with the passage of the insertable top portion.
US11667000B2 Cutting machine
A cutting machine having a work surface, configured to accommodate at least one object to be cut, a working group, which is movable above the work surface including a receptacle device for accommodating a replaceable cutting tool, and a processing unit for controlling the cutting machine and storage capacity for providing a database, characterized by a first sensor unit, which is designed to detect individual items of identification information of the cutting tool and to provide detected items of identification information to the processing unit, wherein the processing unit is designed to recognize the cutting tool based on the items of identification information, to detect operating data of the cutting tool and store these data in the database, wherein the operating data comprise at least one operating time of the cutting tool, and to carry out operational monitoring of the cutting tool based on the operating data.
US11666998B2 Rigid insert shape control in layer jammming systems and methods
Systems and methods are provided for gripping of a workpiece with a layer jamming structure having rigid datum structures. A system includes a layer jamming structure configurable in an inactivated conformable state, with a membrane defining an internal cavity containing a number of overlapping material layers. The rigid structures engage the layer jamming structure. A pressure system includes a pump coupled with the internal cavity to change a pressure therein to transform the layer jamming structure from the inactivated conformable state to an activated rigid state disposed around the workpiece. The rigid structures help conform the layer jamming structure to the workpiece during transformation to the activated rigid state and to present datum fixturing surfaces in the activated rigid state.
US11666997B1 Precision locating fastening device
A precision locating fastening device for securing a part. The device includes a drive screw, a base member, and a stop member. The drive screw has a gripping surface. The base member houses the drive screw and has a precision locating surface. The part is retained and located adjacent the precision locating surface relative to a fixture plate. The drive screw has one or more keyed ends. The stop member is replaceable to maintain precision and accuracy while locating and retaining the part. The device is incorporated in a system where a first keyed end of a first fastening device, a second key of the first fastening device, or the keyed end of a drive screw of a second fastening device is adjusted from either the first side of the fixture plate, the second side of fixture plate, or both to retain and locate the part on the fixture plate.
US11666996B2 Indexing apparatus and method of indexing
An indexing apparatus includes a fixture tool, movable relative to an operation cell, and an indexing feature, fixed relative to the fixture tool. The indexing apparatus also includes a plurality of probes, configured to engage the indexing feature. The indexing apparatus further includes a controller, in communication with the plurality of probes, wherein the controller is configured to locate the fixture tool relative to the operation cell from a plurality of probe locations of the plurality of probes, engaged with the indexing feature.
US11666995B2 Pipe spinner and lifter
In one aspect there is provided a pipe spinner and lifter for supporting and rotating a cylindrical member having a longitudinal axis. The pipe spinner and lifter comprises a pair of jaws that pivot about a pivot member, to allow the pipe spinner and lifter to actuate between an open configuration and a closed configuration. A plurality of rollers are mounted on the jaws, each rotatable about a rolling axis. When the pipe spinner and lifter is in the closed configuration, the cylindrical member can be rotatably captured by the pipe spinner and lifter, allowing the cylindrical member to rotate about its longitudinal axis. Preferably, the plurality of rollers are arranged in a substantially mirrored arrangement on the jaws. More preferably, the rolling axis of each of the rollers is substantially parallel to the cylindrical member's longitudinal axis.
US11666991B2 Laser machining apparatus and laser machining method
A moving mechanism relatively moves a machining head emitting a laser beam, with respect to a sheet metal along a surface of the sheet metal. A beam vibrating mechanism vibrates the laser beam for irradiation on the sheet metal in a predetermined vibration pattern, while the machining head is relatively moved by the moving mechanism. A vibration control section controls the beam vibrating mechanism to progressively reduce an amplitude of the vibration pattern from a first position to a corner portion when the machining head moves toward the corner portion and reaches the first position before the corner portion by a predetermined distance, and progressively increase the amplitude of the vibration pattern until the machining head reaches a second position ahead of the corner portion by the predetermined distance from the corner portion, at a time of producing a product having the corner portion.
US11666984B2 Exothermic welding with non-communicated cavities
A mold includes a weld cavity, housings for the components to be welded, a crucible-funnel in communication with the weld cavity for housing filling material, at least one additional cavity for housing an exothermic mixture; and an inner shell that separates the crucible-funnel and the at least one additional cavity to transmit heat produced in the exothermic reaction from the additional cavity to the crucible-funnel. The mold allows the exothermic mixture to be isolated to avoid contact with the filling material and to prevent the filling material from reaching the weld cavity. The system can further include a first filler and a second filler, arranged to be mounted over the mold for introducing the filling material and the exothermic mixture, respectively.
US11666982B2 Method and device for providing a referenced distance signal for controlling the position of a welding torch
A method for providing a referenced distance signal which corresponds to the distance between a contact tip of a welding torch and a workpiece to be machined, includes adjusting an operating point on a predetermined welding characteristic, which is defined at least by a wire feed rate, a welding voltage and/or a welding current, and a CTWD distance between the contact tip and the workpiece; determining a target parameter value of at least one parameter dependent on the CTWD distance for the operating point; determining an actual parameter value of the at least one parameter by measuring at least one of the present wire feed rate, welding voltage and/or welding current; modifying the determined actual parameter value as a function of a calculated difference between the target parameter value and a predetermined reference value; and outputting the referenced distance signal corresponding to the modified actual parameter value to a position control system of a robot arm.
US11666981B2 Welding method and apparatus therefor
A welding process involves a fixture for holding a workpiece and a welder, or welding electrode. The fixture imposes ultrasonic vibration on the workpiece. The welder vibrates during vibration, and is operable at a first voltage for welding and a second voltage for peening. The peening may occur while the weldmetal is crystallizing. The welding process may be a process of welding two part as together, or of filling a groove or other feature, or of applying or restoring a surface, or of applying a hard facing or ceramic to a parent metal or object. The weldmetal may be the same, or substantially the same, as the parent metal, or it may be different. The different material may be a ceramic material.
US11666980B2 Work hardened welds and methods for same
A tube assembly includes at least first and second tubes configured for coupling at respective ends. The first and second tubes each include a base material, and a weld interface at the respective end. The weld interface is proximate to an inner diameter and an outer diameter of the first and second tubes, and includes a weld interface segment extending therebetween. A work hardened weld assembly couples the base material of each of the first and second tubes. The work hardened weld assembly includes a weld fusion zone between the weld interfaces of the first and second tubes and the weld interface segments of the first and second tubes. The weld fusion zone is work hardened and at least the weld interface segments of the first and second tubes are work hardened between the work hardened weld fusion zone and the base material of the first and second tubes.
US11666971B1 Additive manufacturing system and method
An additive manufacturing system including a two-dimensional energy patterning system for imaging a powder bed is disclosed. Improved structure formation, part creation and manipulation, use of multiple additive manufacturing systems, and high throughput manufacturing methods suitable for automated or semi-automated factories are also disclosed.
US11666969B2 3D printing device and 3D printing method
A 3D printing device for producing a three-dimensional component form at least two different materials. The 3D printing device has both a spray-printing unit and an electron-beam and/or laser unit. To produce the three-dimensional component, the spray-printing unit is designed and set up to spray the at least two different materials, and the electron-beam and/or laser unit is designed and set up to join sprayed-on material integrally by fusing by means of an electron beam and/or by means of a laser beam of the electron-beam and/or laser unit.
US11666966B2 Powder molding press method of green compact for cutting insert, and powder molding press device
A powder molding press method of a green compact for a cutting insert including: filling a molding space with raw material powder in a state where a lower punch is inserted from below into a hole portion of a die; performing preliminary molding by inserting an upper punch for preliminary molding including a preliminary molding surface having a shape different from a shape obtained by inverting the upper surface of the green compact for a cutting insert in a plane symmetry into the molding space from above such that a thick portion between the upper and lower surfaces in the direction of the insert center line is filled with more raw material powder than a thin portion therebetween, relative to a state before the step of performing the preliminary molding; and inserting an upper punch for final molding into the molding space from above to powder-molding-press the raw material powder.
US11666965B2 Slab warpage detection apparatus and method of detecting warpage of slab
Provided is a slab warpage detection apparatus detecting warpage of a slab drawn from a mold in continuous casting equipment. The slab warpage detection apparatus includes a pair of pressing roils that pinches the slab on a rear side of a roll segment, supporting the slab drawn from the mold, in a slab drawing direction, a movement unit that supports the pair of pressing rolls to be movable in a thickness direction of the slab, and a position detecting unit that detects positions of the pressing rolls in the thickness direction of the slab.
US11666962B2 Systems and related methods for manufacturing ring pull bottle crowns
Equipment and related methods for manufacturing ring pull crowns are disclosed herein. In one embodiment, a method of manufacturing a ring pull crown may include forming a plurality of crown bodies from a first source material, and forming a plurality of pull ring and tab assemblies from a second source material. In addition, such a method may include forming a plurality of ring pull crowns by combining each crown body of the plurality of crown bodies with a corresponding pull ring and tab assembly from the plurality of pull ring and tab assemblies. Also, such method may also include forming a circumferential skirt that descends below a top of each ring pull crown, and removing the plurality of ring pull crowns from the first source material.
US11666961B2 Cam follower assembly for can bodymaker and can bodymaker including same
A cam follower assembly for a can bodymaker includes a slider structured to be coupled to the proximal end of a ram body of the can bodymaker; and a plurality of cam follower members rotatably coupled to the slider. The cam follower members are structured to be operatively coupled to a cam of a ram drive assembly.
US11666960B2 Workpiece accumulator for a stamping machine
A workpiece accumulator system for a stamping machine includes linear actuators, nesting blocks, exit rails, and a first controller. The nesting blocks are disposed on moveable members of the linear actuators and arranged to vertically stack workpieces being fabricated by the stamping machine. The first controller communicates with a second controller that controls the stamping machine. The first controller controls the linear positions of the linear actuators to retract the nesting blocks from an initial position to accommodate placement of the one of the plurality of workpieces in a stack on the nesting blocks. The linear actuators are controlled to retract the nesting blocks to fully retracted positions to place the plurality of workpieces in the stack onto the exit rails when a quantity of the plurality of workpieces in the stack is equal to a desired quantity.
US11666959B2 Forming tool and method for producing a component
A forming tool includes at least one first die half where the first die half has an insert part which is designed to move a finished component out of the first die half along a direction of motion where a displacement direction of the insert part is inclined relative to the direction of motion.
US11666958B2 Reflex angle capable tube bending systems with crank assemblies
Tube bending devices including a device actuator, a crank assembly, a bending die, and a clamp assembly. The crank assembly is mechanically coupled to the device actuator. The bending die is mechanically coupled to the crank assembly. The clamp assembly is operatively coupled to the bending die and secures the tube to the bending die. The device actuator selectively drives the crank assembly. In some examples, the crank assembly selectively rotates the bending die over at least 180 degrees. In some examples, the bending die includes an axle and the crank assembly includes a first link, a crank actuator, and a second link. The first link is pivotally coupled to the device actuator and coupled to the axle. The crank actuator is pivotally coupled to the first link. The second link is pivotally coupled to the crank actuator and coupled to the axle.
US11666953B2 Storing hazardous material in a subterranean formation
Methods for storing or disposing of nuclear waste include forming a drillhole that extends into the Earth from a terranean surface. The drillhole includes an entry at least proximate the terranean surface, a substantially vertical drillhole portion, and a hazardous material storage drillhole portion that is coupled to the substantially vertical drillhole portion and is formed in a subterranean salt formation. The methods further include moving a storage canister into the hazardous material storage drillhole portion. The storage canister is sized to fit from the drillhole entry through the substantially vertical drillhole portion, and into the hazardous material storage drillhole portion of the drillhole. The storage canister has an inner cavity that encloses nuclear waste material. The methods further include positioning a seal in the drillhole to isolate the hazardous material storage drillhole portion of the drillhole from the entry of the drillhole.
US11666951B2 Wafer handler cleaning tool
A wafer handler cleaning tool may include a scraping device positioned near semiconductor equipment (e.g., a cooling plate, a semiconductor processing device, and/or the like) such that the scraping device removes foreign objects, debris, and/or other types of matter from the underside of the wafer handler when the wafer handler loads a wafer into the semiconductor equipment and/or unloads the wafer from the semiconductor equipment. Moreover, the wafer handler cleaning tool may include a negative pressure device to draw the removed foreign objects, debris, and/or other types of matter away from the scraping device and toward a filtration device such that the filtration device captures the removed foreign objects, debris, and/or other types of matter.
US11666947B2 Selector machine
Selector machine comprising an optical detection system provided with an emitter device and with an optical sensor adapted to detect a product to be selected. The emitter device comprises three IR sources, each of which emits electromagnetic radiations in a corresponding spectral band in the infrared spectrum. An electronic control unit alternately turns on the IR sources in corresponding separate time intervals, and the optical sensor detects, in each time interval, corresponding reflected radiations coming from the product. In addition, the electronic control unit comprises a processing module, which is provided with three chromatic channels of a RGB color space in order to associate the measurement signals corresponding to each IR source with a corresponding chromatic channel so as to compose a false color synthesis image of the product.
US11666944B1 Detection of overfilled containers in sortation systems
Systems, methods, and computer-readable media are disclosed for detection of overfilled containers in sortation systems. In one embodiment, an example container capacity detection system for use with an item sortation machine may include a first sensor positioned to detect a remaining capacity of a first container in the item sortation system, and a controller. The controller may be configured to determine, using the first sensor, that the remaining capacity of the first container is less than or equal to a first threshold, and to send a signal.
US11666943B2 Sizing and separating granular particles
A system and method for sizing and separating granular particles within the bulk granular solids by creating a graded granular flow comprising multiple sized fractions with gradation of the particles according to particle size between relatively fine fractions and relatively coarse fractions; and capturing at least a portion of granular flow. The system (11) comprises means (25) for creating the graded granular flow, and means (30) for capturing at least a portion of the graded granular flow. The graded granular flow is split into separate streams, one of which is subsequently captured by intercepting that stream. The intercepted stream may be collected or redirected for further processing.
US11666940B2 Rapid mercury-free photochemical microencapsulation/nanoencapsulation at ambient conditions
A method of mercury-free photochemical micro-/nano-encapsulation of an active material is a process for obtaining Micro-/nano-capsules by means of curing by UV LED radiation at ambient or even cold temperatures. A stirrer photo-reactor made from glass or transparent plastics can be used but mixed flow reactor could be also employed. Appropriate mixing is sufficient to expose all droplets, which contain an active material surrounded by curable-shell materials in the emulsion to the LED radiation. Using the optimum light intensities and reactions' times is critical for encapsulating the active material with a high efficiency and producing a high quality micro-/nano-capsules, Solar monochromator device can also be used as long as it generate the same radiation with a narrow/single wavelengths as the LED device. Light emitted diode (LED) is a mercury-free UV radiation source with a long operating life time and an instant ON-Off, it has a high efficiency, a very low cooling requirements and cost-efficient in photochemical encapsulation. It reduces the time of microencapsulation from 6 hours to a less than 5 minutes. It has a significant decrease in manufacturing cost, waste-water, unconverted monomers, and leftover active phase change material (PCM) compared to other methods. Conversion of more than 90% of monomers can be achieved, and encapsulation efficiency can reach 100% at optimum conditions. This is in addition to the ability of this invented technology for encapsulate volatile and heat sensitive active materials at ambient as well as low temperatures. Normal glass or transparent plastics can be used as a reactor material. Only the matched useful wavelength radiation is emitted by LED without having other wavelengths which might have a bad impact on the encapsulation process.
US11666938B2 Liquid patterning device and method
Disclosed is a liquid patterning device and liquid patterning method. The liquid patterning device includes: a substrate having a flat bottom and a surface; at least one microstructure formed to vertically protrude from the surface of the substrate and including a plurality of unit microposts so as to have a desired shape; and a liquid mover for moving a liquid to be patterned on the surface of the substrate in another direction from one direction of the microstructure.
US11666937B2 Method for coating a building panel and a building panel
A method for coating a building panel, including applying a first coating fluid including an organic binder on a surface of the building panel to obtain at least one coating layer, and applying barrier components and photocatalytic particles, preferably TiO2, on the at least one coating layer. Also, a building panel formed by the method.
US11666936B2 Device and method for scaling and coating of continuous multi-material stripes and patterns
A hybrid scaling and patterning apparatus for producing thin films with multi-material, customized patterns is disclosed. The apparatus includes a slot die body integrated with multiple inlets and corresponding converging channels passing materials through the die body in a planar, continuous laminar flow. The hybrid scaling and patterning apparatus may be used in a method of preparing multi-material, patterned thin film materials.
US11666935B2 Selectively lifting substrates
Example implementations relate to selectively deflecting substrates. One example implementation includes an apparatus to selectively lift a part of a substrate away from a transfer member when the substrate is advancing in a substrate coating system relative to the transfer member, such that, across a width of the substrate, a first part of the substrate is coated by the transfer member and a second part of the substrate, that is lifted by the apparatus, remains uncoated.
US11666934B2 Spray gun and nozzle assembly attachment
A liquid spray gun nozzle assembly is disclosed comprising a coating liquid inlet portion comprising a liquid connector for connection to an external liquid source; a coating liquid outlet portion comprising a liquid nozzle for spraying a coating liquid fed into the nozzle assembly through the coating liquid inlet portion, the liquid nozzle being disposed along a spray axis; a coating liquid flow path fluidly connecting the coating liquid inlet portion to the liquid nozzle; and a spray gun connection portion opposite the coating liquid outlet portion adapted to connect the liquid spray gun nozzle assembly to a compatible liquid spray gun body. The spray gun connection portion comprises a nozzle assembly sealing surface adapted to seal the liquid spray gun nozzle assembly to the compatible liquid spray gun body, the nozzle assembly sealing surface comprising first and second sealing members that are each circular and concentric with one another.
US11666932B2 Fluid applicator
A fluid applicator configured to receive a pressurized fluid includes a pressure vessel configured to receive the pressurized fluid from a fluid delivery line. The pressure vessel includes a valve chamber configured to receive a valve assembly, a filter chamber configured to receive a filter assembly, and a fluid delivery line fitting configured to be coupled to the fluid delivery line. The fluid applicator further including a tip assembly coupled to the pressure vessel and configured to atomize the pressurized fluid.
US11666931B2 Inline shower device
An inline shower device includes a housing, a hydraulic chamber, a first actuator, and a fluid-driven piston. The housing includes an outlet port. The hydraulic chamber is disposed within the housing. The first actuator is configured to connect a capsule to the housing and to fluidly connect the capsule to the hydraulic chamber. The fluid-driven piston is disposed within the hydraulic chamber and is configured to dispense a fluid from the capsule into the outlet port.
US11666930B2 Sprinkler device for an irrigation liquid and method of diffusion of an irrigation liquid with such sprinkler device
A sprinkler device for delivering an irrigation liquid for gravity-based pivot or linear irrigation systems includes a support structure having a first portion with a nozzle defining a longitudinal axis for generating a jet of liquid, and a second portion with a baffle plate pivoted thereto and facing the nozzle. The second portion includes a drive system, which has a first magnet moving with a reciprocating oscillatory motion due to a negative pressure generated by the liquid that flows through the nozzle, and is configured to move the baffle plate along, and force it to pivot with a reciprocating oscillatory motion about the longitudinal axis through a predetermined angle, to thereby deliver the liquid over a sector area of the soil. A method of delivering an irrigation liquid for gravity-based pivot or linear irrigation systems that uses such a sprinkler device.
US11666928B2 Vortex ring generation device
A vortex ring generation device includes a casing and an extrusion mechanism. The casing has a gas passage and a discharge port. The extrusion mechanism extrudes gas in the gas passage such that the gas in a vortex ring shape is discharged from the discharge port. V (m3) represents an extrusion volume, D (m) represents a diameter of the discharge port, L (m) represents a length of a cylinder having the diameter D and the volume V, and U (m/s) represents a discharge flow rate 0.045≤D≤0.135, 0.15≤L≤0.35, and 3≤U≤5.
US11666923B2 Split pulp chamber insert assembly
A split pulp chamber insert assembly formed for installation in a pulp chamber on a discharge end wall in a grinding mill rotatable about an axis thereof. The split pulp chamber insert assembly include two or more insert elements, configured to cooperate to form a lining covering one or more portions of pulp chamber surfaces that partially define the pulp chamber in which the insert elements are positioned. The split pulp chamber assembly also includes a number of fasteners, for securing the insert elements in predetermined positions in the pulp chamber relative to each other to form the lining that covers the one or more portions of the pulp chamber surfaces.
US11666921B2 Systems and methods for crushing clay, transporting clay, and processing clay
Provided are methods and apparatus for crushing clay, transporting clay, and processing clay. In examples, provided are movable truss conveyor support apparatuses, movable crusher picker apparatuses, picker shaft rakes to clean picker shafts, adjustable hoppers, and tracked crushers. In an example, provided is a crusher including (i) a crusher frame, (ii) a crusher subframe movably suspended from the crusher frame, (ii) a rotary bearing fastened to the crusher subframe, (iv) a rotatable picker shaft rotatably supported by the rotary bearing and adapted to rotate relative to the crusher subframe, and (v) at least one picker fastened to the rotatable picker shaft.
US11666920B2 Method of cleaning aspiration tube and specimen measuring apparatus
A method of cleaning an aspiration tube in a specimen measuring apparatus includes: moving the aspiration tube while discharging a cleaning liquid onto an outer side surface of the aspiration tube; stopping the aspiration tube in a state where a tip of the aspiration tube or a droplet attached to the tip contacts a surface of a flow of the cleaning liquid; and moving the stopped aspiration tube in a direction away from the surface of the flow of the cleaning liquid.
US11666918B2 Microfluidic chip, head, and dispensing device for dispensing fluids containing an acidic component
A microfluidic ejection chip includes a silicon substrate having a fluid passageway. The fluid passageway is defined by a silicon sidewall of the silicon substrate that is covered by a permanent passivation layer to protect the silicon sidewall from exposure to an acidic fluid. The permanent passivation layer is retained on the silicon sidewall at a conclusion of etching of the silicon substrate to form the fluid passageway.
US11666915B2 Cell classification chip
A chip includes a micro-channel unit for hydraulically classifying cells in a blood sample. In a micro-channel unit, liquid flowing from a sub channel into a main channel pushes cells flowing in the main channel toward a side thereof on which a removal channel and a collection channel are disposed. Fluid containing non-nucleated RBCs among the pushed cells enters the removal channel, so that the non-nucleated RBCs are removed from a blood sample. A plurality of micro-channel units having the same patterns as each other are repeatedly stacked in a height direction. Inlets of the main channels, inlets of the sub channels, outlets of the removal channels, outlets of the collection channels, and outlets of the main channels, which are provided in the micro-channel units, are connected to respective pillar channels penetrating each of layers in a traversing manner.
US11666914B2 Cartridge, electrowetting sample processing system and bead manipulation method
A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge contains an internal gap with at least one hydrophobic surface for enabling an electrowetting induced movement of a microfluidic droplet that has magnetic beads and further has a bead accumulation zone, into which the microfluidic droplet is transferable by electrowetting force and the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap has a bead extraction opening adjacent to the bead accumulation zone. The bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet.
US11666912B2 Sorting of T lymphocytes in a microfluidic device
Methods of sorting T lymphocytes in a microfluidic device are provided. The methods can include flowing a fluid sample comprising T lymphocytes through a region of a microfluidic device that contains an array of posts. The array of posts can be configured to have a critical size (Dc) that separates activated T lymphocytes from naïve T lymphocytes. Also provided are microfluidic devices having an array of posts configured to separate activated T lymphocytes from naïve T lymphocytes, compositions enriched for T lymphocytes, particularly activated T lymphocytes that are known to be reactive to an antigen of interest, and methods of treating subjects suffering from a pathogenic disorder or cancer by administering such compositions.
US11666907B2 Methods, devices, and systems for detecting analytes
This document provides methods, devices, and systems for detecting the presence, absence, or amount of one or more analytes. For example, this document provides methods for using graphene-based sensors to detect one or more analytes (e.g., proteins, nucleic acids, intact cells, intact viruses, intact microorganisms, and/or chemicals).
US11666906B2 Parts for diagnostic devices
In some examples, a diagnostic device includes a reusable part to receive a container of a fluid, the reusable part reusable for a plurality of diagnostic tests. The diagnostic device further includes a disposable part detachably attached to the reusable part and comprising a sample collector to collect a target sample of a living being. The diagnostic device further includes a tester comprising a fluid channel to transport the fluid to combine the fluid and the target sample to form a fluid combination, and to use the fluid combination to diagnose a condition of the target sample.
US11666905B2 Triboelectric nanogenerator-based biochemical droplet reaction device and method
Disclosed is a triboelectric nanogenerator-based biochemical droplet reaction device, which includes a reaction generating part and a power generation part. The power generation part includes a triboelectric component and a rectifier circuit. The triboelectric component includes a drive electrode, a substrate, a first friction electrode, a first friction material, a second friction material, and a second friction electrode arranged in sequence from top to bottom. A gap exists between the first friction material and the second friction material. The first friction electrode is connected to the first friction material. The second friction electrode is connected to the second friction material. The drive electrode, the first friction electrode, and the second friction electrode are all connected to the rectifier circuit. Also disclosed is a reaction method.
US11666904B2 Fluid handling system
A fluid handling system includes a fluid handling device including an opening for introducing a fluid or discharging the fluid; a tube including a flange, where one end of the tube is for connection to the opening, and the other end of the tube is for connection to an introduction device for supplying the fluid or to a discharge device for discharging the fluid; a support member including a first through hole into which the tube is inserted, and movably supporting the tube; and a first elastic member including a second through hole into which the tube is inserted, and holding a part of the tube while the first elastic member is in contact with the flange and the fluid handling device or the support member.
US11666902B2 Modular fluidic chip and fluidic flow system comprising same
A modular fluidic chip includes a body configured to have at least one flow channel formed in an inside thereof and be connected to another modular fluidic chip to allow the at least one flow channel to communicate with a flow channel provided in the other modular fluidic chip. A fluidic chip capable of performing one function is formed in the form of a module, whereby a fluidic flow system of various structures can be implemented without restriction in shape or size by connecting a plurality of fluidic chips capable of performing different functions as necessary. Through this, various and accurate experimental data can be obtained, and when a specific portion is deformed or damaged, only the fluidic chip corresponding thereto can be replaced, thereby reducing manufacture and maintenance costs.
US11666900B2 Motion controlling mechanism, liquid discharging nozzle, microdroplet generating device and method, liquid driving mechanism and method, microdroplet generating method, and surface processing method of liquid discharging nozzle
Disclosed is a liquid discharging nozzle, including a needle stem having a hollow chamber and an outlet end located at one end of the needle stem, an angle between a normal line of an end surface of the outlet end of the liquid discharging nozzle and an extension direction of the needle stem is equal to or smaller than 90°. Further disclosed are a motion controlling mechanism, a microdroplet generating device and method, a liquid driving mechanism and method, a microdroplet generating method, and a surface processing method of a liquid discharging nozzle.
US11666897B2 Honeycomb bodies with multi-zoned honeycomb structures and co-extrusion manufacturing methods
A honeycomb body with a honeycomb structure having an inner zone of a first plurality of walls and an outer zone of a second plurality of walls at least partially surrounding the inner zone. The honeycomb structure has Pi that is greater than Po and MPSi that is greater than MPSo, wherein Pi is an average bulk porosity of the first plurality of walls, Po is an average bulk porosity of the second plurality of walls, MPSi is a median pore size of pores in the first plurality of walls, and MPSo is a median pore size of pores in the second plurality of walls. Various honeycomb structures, honeycomb extrusion apparatus, and co-extrusion methods are disclosed.
US11666896B2 Catalyst composition with improved chemical warfare agent degradation ability and processability
Provided are a catalyst composition with improved processability and chemical warfare agent degradation ability, a film composite manufactured by casting the same, and a preparation method thereof. Specifically, provided are a catalyst composition including a copolymer of a first polymer and a second polymer; and a metal-organic framework (MOF), and a film composite including the same, wherein processability and catalytic activity are improved.
US11666894B2 Structured catalyst for CO shift or reverse shift and method for producing same, CO shift or reverse shift reactor, method for producing carbon dioxide and hydrogen, and method for producing carbon monoxide and water
Provided are a structured catalyst for CO shift or reverse shift that can realize a long life time by suppressing the decline in function, a method for producing the same, a CO shift or reverse shift reactor, a method for producing carbon dioxide and hydrogen, and a method for producing carbon monoxide and water. The structured catalyst for CO shift or reverse shift (1) includes a support (10) of a porous structure composed of a zeolite-type compound, and at least one CO shift or reverse shift catalytic substance (20) present in the support (10), the support (10) has channels (11) connecting with each other, and the CO shift or reverse shift catalytic substance (20) is present at least in the channels (11) of the support (10).
US11666893B1 Methods for preparation and use of liquid synthesis catalysts
Described herein are catalysts relating to liquid synthesis, methods of their preparation, and methods of their use. In an embodiment according to the present disclosure, a method of producing a catalyst for liquid synthesis comprises: providing a silica oxide support; pretreating the silica oxide support to remove air and moisture; impregnating the pretreated silica oxide support with cobalt from a cobalt source using a cobalt impregnation method; and calcinating the impregnated silica oxide support in an oven with a temperature ramping profile, wherein the calcinating comprises feeding air into the oven.
US11666890B2 Porous ceramic structure
A porous ceramic structure with low pressure loss and high catalytic performance is provided. The porous ceramic structure includes a porous structure body (i.e., honeycomb structure) composed primarily of cordierite, and manganese (Mn) and tungsten (W) that are fixedly attached to the honeycomb structure. Thus, pressure loss in the porous ceramic structure can be reduced, and an NO combustion temperature in the porous ceramic structure can be lowered. In other words, the aforementioned structure of the porous ceramic structure allows the porous ceramic structure to have low pressure loss and high catalytic performance.
US11666887B2 Hydrocarbon adsorbent
A hydrocarbon adsorbent includes a core-shell particle including a core and a shell surrounding the core, wherein the core includes ion-exchanged zeolite that is ion-exchanged with a metal other than silicon (Si) and aluminum (Al) and the shell includes a mesoporous metal oxide.
US11666883B2 Plant for the synthesis of melamine with offgas recovery in a tied-in urea plant
Plant for the synthesis of melamine starting from urea, wherein the stream of offgas containing NH3 and CO2 produced by the synthesis of melamine is converted into urea in a dedicated urea plant.
US11666876B2 Compounder apparatus
A system including a containment assembly for enclosing a medication container may comprise a first housing portion or interface portion having a proximal end and a distal end. The interface portion may include a housing wall which defines a channel spanning from the proximal end to the distal end. The channel may be open at the proximal and distal end. The containment assembly may further comprise only two pierceable septa configured to form a barrier to the channel. The containment assembly may further comprise a variable-volume housing portion having a variable volume chamber. The variable-volume portion chamber of the variable-volume housing portion may be in fluid communication with the distal end of the channel.
US11666875B2 Secure portable, on-demand, microfluidic mixing and dispensing device
A dispensing device, comprising a plurality of microfluidic pumps, microfluidic valves, and a microfluidic mixer chip, for receiving and mixing microfluidic amounts of a plurality of fluids having differing viscosities, is disclosed. The device includes a plurality of pathways for moving fluids from associated reservoirs to the microfluidic mixer chip. A mix controller controls the microfluidic pumps and valves so that the fluids, having different viscosities, can be accurately mixed at specified microfluidic amounts or volumes according to a specified microfluidic recipe, and the microfluidic mixture dispensed from the device. The device can be in communication with a software application implemented on a mobile compute device, such as a smartphone, and receive instructions for implementing the specified microfluidic recipe from the software application such that the operation of device components is at the direction of the software application executed on the mobile compute device.
US11666874B2 Methods and apparatus for variable emulsification
The invention comprises a novel modular, generalizable meso-micro-nano-fluidic platform apparatus, design and methodology which in exemplary embodiments may be applied in conjunction with a novel external triggering and automation/feedback loop control mechanism deployed via computer to explore the phase space of single or double emulsification for applications including the encapsulation of hydrophilic active pharmacological ingredients (APIs). End use applications include the mass production of particulate encapsulation of hydrophobic or hydrophilic APIs with automatic or user-supervised feedback methodology to control and discover mass production or per-drug customized settings of interest for the manufacture of novel or extant therapeutics. This invention allows for a process to produce monodispersed particles of varying sizes and may be used to rapidly screen for optimal size for maximal bioavailability of API particles either on lab bench for in vitro dissolution or in vivo studies, and patient-specific handhelds for maximal drug inhalation.
US11666873B2 Method and device for sonicating a biological sample
The present disclosure relates to a device for sonicating a biological sample. In one embodiment, a sample tube holder is pivotally suspended in a mount of a sonication device, thus allowing for a rotational degree of freedom and/or lateral movement that provides an optimized contact area between the sonotrode and the sample tube. Also disclosed is a method for sonicating a biological sample using the device described herein.
US11666872B2 Containers for agitation of liquid samples and methods of use thereof
The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.
US11666870B2 Venturi mixer with adjustable flow restrictor
An apparatus for mixing a liquid and a substance, including a housing with a liquid inlet and a substance inlet to a mixing chamber, an outlet for a mixture of liquid and substance, and a flow restrictor arranged in the housing, between the liquid inlet and the mixing chamber. The flow restrictor is controllable to switch between a first position providing a first through flow area configured to create a Venturi effect such that a flow of the liquid draws the substance into the mixing chamber, and a second position providing a second through flow area that is larger than the first through flow area to thereby decrease a pressure drop caused by the flow restrictor.
US11666869B2 Hemodialyzer for blood purification
The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
US11666866B2 Carbon nanomembranes on porous materials
A method for manufacturing a porous device (10) is described. The method comprises creating (340) a carbon nanomembrane (40) on a top surface (22) of a base material (20) having latent pores (23) and etching (360) the latent pores (23) in the base material (20) to form open pores (24). The porous device (10) can be used as a filtration device.
US11666860B2 Methane destruction apparatus and method of converting fugitive methane emissions
A methane destruction apparatus for capturing and converting fugitive methane gas emissions into carbon dioxide and water comprises a methane-capturing module for capturing the fugitive methane gas emissions and a methane conversion module for receiving captured methane from the methane-capturing module. The methane-capturing module includes a fugitive methane gas emission intake connected to an emissions line having a backpressure equal to 1 to 3 inches of water (249 to 746 Pa), a natural gas feed for feeding natural gas into the methane-capturing module, may include a relief vent for preventing overpressure within the methane-capturing module and a drain for draining liquids that have condensed within the methane-capturing module. The methane conversion module includes a conversion pad for catalytically converting the captured methane into carbon dioxide and water, a water vapour opening for outputting the water and a carbon dioxide opening for outputting the carbon dioxide.
US11666858B2 Method for determining process conditions to remove volatile organic compounds from polymer
The present application relates to a method for determining process conditions to remove volatile organic compounds from a polymer product through blowing. According to the method of the present application, time and energy can be saved.
US11666856B2 Air composition adjusting device
An air composition adjusting device includes: an oxygen separator that separates oxygen from external air to be supplied to a target space; a gas supply path including a high concentration gas supply path for oxygen through which the oxygen separator communicates with the target space; and a controller that performs an oxygen concentration raising operation of supplying a high oxygen concentration gas, which has a higher oxygen concentration than external air before being treated by the oxygen separator, to the target space through the high concentration gas supply path for oxygen.
US11666847B2 Cage assembly for dislodging material buildup within pneumatic conveyance systems and related methods
A pneumatic conveyance system includes at least one filtration component and a cage assembly disposed within the filtration component. The cage assembly may include a first cage, a second cage, and an actuator, where the actuator may be configured to move the first cage relative to the second cage and cause at least a portion of the first cage to rub against a filtration component within the pneumatic conveyance system. A method of dislodging material buildup within a pneumatic conveyance system includes causing a first cage of a cage assembly to move relative to a second cage within a filtration component.
US11666845B2 Air purification device
A purification device for disinfecting and filtering intake air is disclosed. The purification device comprises a housing provided with a number of inlet perforations for allowing the intake air to enter the housing and a number of air outlet perforations for allowing air purified by the purification device to leave the housing. The purification device moreover comprises a fan arranged inside the housing to suck the intake air into the housing and blow the purified air out of the housing. The purification device further comprises an ultraviolet radiation lamp arranged inside the housing to irradiate the intake air. The purification device also comprises a high-efficiency particulate air (HEPA) filter arranged to filter the intake air before the intake air leaves the housing as purified air. The filter comprises a plurality of pleats arranged in such a manner that the angle between adjacent pleats is 30 degrees or less.
US11666844B2 Filtration device having a latch mechanism adapter
A filtration device may include an adapter, a filter element, and a housing. The adapter may include a collar having an upper rim and a lower rim, a plurality of locking tabs extending from the upper rim, and a plurality of snap members extending from the lower rim. The filter element may include a casing and a plurality of receptacles connected to and arranged around a first outer surface of the casing. The plurality of receptacles are configured to receive the plurality of locking tabs. The housing, which is configured to receive the filter element, includes a shell and a plurality of ramp members that are connected to a second outer surface of the shell. The plurality of ramp members are configure to engage the plurality of snap members.
US11666843B2 Assemblies; components and filter features thereof; and, methods of use and assembly
An air cleaner assembly is disclosed, along with related methods. In one aspect, the air cleaner assembly has a housing including a housing body and a removable cover that together define an interior volume for holding a filter cartridge. The housing body can include a first plurality of lugs, wherein each of the first plurality of lugs has a first engagement surface disposed at a first angle that is oblique to a rotational plane of the cover. A second plurality of lugs can be provided on the cover, wherein each of the second plurality of lugs has a second engagement surface disposed at the first angle. A lock mechanism can also be provided that is disposed on the cover, wherein the lock mechanism includes a lock member axially movable between a locked position and an unlocked position to selectively secure the cover to the housing body.
US11666842B2 Device that selectively delivers molecular active components and reduces airborne contaminants
Described herein are devices and components for same, e.g., filters cartridges, which are able to filter contaminants while allowing active ingredients, e.g., nicotine, to pass through.
US11666839B2 Oil filtration assembly, system, and methods of making and using the same
An oil filtration assembly is described herein comprising a container having an upper end portion and a lower end portion, an oil reservoir formed on the lower end portion of the container, and a removable oil filter subassembly integrated with the upper end portion of the container. The subassembly comprises a filter housing including an inlet configured to receive oil and a filtered oil outlet configured to permit an outward flow of oil into the oil reservoir, a filter contained in the housing and disposed between the inlet and the filtered oil outlet, and a top component configured to be removed for replacement of the filter. The oil filtration-reservoir assembly further includes an inlet service valve, an oil outlet service valve and at times a service valve for the vent line. Corresponding systems and methods also are disclosed.
US11666836B2 Extraction of cannabinoids from cannabis
Methods and processes for efficiently extracting cannabinoids from cannabis are described together with cannabis extracts obtained using such methods. A method may include: preparing a premixture by mixing dried cannabis with an extraction agent; incubating the premixture; and after incubating the premixture, adding a liquid to the premixture to create a liquid mixture and filtering the cannabis from the mixture.
US11666835B2 Multi-function distiller
A multi-functional distiller for separating target compounds from a base material. The distiller has a basket, boiling tank, and sealable cap. The basket has at least one selectively sealable port for holding the base material. The boiling tank is adapted for containing a solvent, and the basket is attachable above the solvent. The sealable cap may be removeably attachable to the boiling tank to provide a sealed chamber. The sealable cap can be fitted with multiple condensers. One possible condenser is positionable exterior to the boiling tank and functions to condense vapors produced by the boiling tank. A second such condenser is an inverted condenser which is positionable interior to the tank so as to condense vapors produced by the boiling tank and cause the condensate to drip through the base material.
US11666833B2 Interactive tower attraction systems and methods
A ride attraction system includes a tower track and a ride vehicle configured to accommodate one or more riders. The ride vehicle is coupled to and configured to move relative to the tower track and the ride vehicle includes one or more user input devices. The ride attraction system further includes an image system configured to display a ride environment, wherein the user input devices are configured to enable the one or more riders to interact with elements of the ride environment via the one or more user input devices. The ride attraction system further includes a controller communicatively coupled to the ride vehicle and the image system and configured to control movement of the ride vehicle relative to the tower track based on signals from the one or more user input devices.
US11666831B2 Systems and methods for determining game events based on a crowd advantage of one or more players in the course of a multi-player video game play session
The present specification describes systems and methods that enable non-players to participate as spectators in online video games and, through a collective voting mechanism, determine the occurrence of certain events or contents of the gameplay in real time. Game event options are generated and presented to non-players. A specific one of the game event options is then selected based on a collective vote of the non-players. Once selected, the specific one or more of the game event options are then generated as actual gaming events and incorporated into a video game stream that is transmitted to the players as part of the gameplay session. In this manner, non-players may be able to directly affect the course of gameplay.
US11666828B2 Computer-executable game on a graphical user interface with validity periods for game content
An information processing device that progresses a game using a game content associated with a player. In response to receiving an obtaining request, the device selects a subset of game contents, where a portion of the game contents has a same identification information and each of the portion of the game contents has a different validity period. The device obtains a validity period associated with each of the selected game contents. When a first game content associated with the player has the same identification information as a second game content, the device updates, for each game content, a validity period of the first game content based on the validity period of the second game content in the subset of game contents. The device then restricts use of the first game content in the game when the validity period of the first game content lapses.
US11666827B2 Systems and methods for capture and use of local elements in gameplay
A computer-implemented method is provided for enabling virtual gameplay. Access is provided to at least one video game in which a player is able to interact with the video game according to a storyline. A player location is detected and stored. A local element is retrieved from a database based on the player location and the local element is correlated to a local element script actuatable in the video game. This local element script is retrieved and actuated in the video game to supplement or replace the video game's storyline.
US11666824B2 Methods, systems, and devices for dynamically applying equalizer profiles
A system that incorporates the subject disclosure may include, for example, an embodiment for detecting a map associated with a gaming session for a video game executing on a computing device associated with a first user, and obtaining a map equalizer profile associated with the map for the video game. Further embodiments can include determining a first avatar, associated with the first user, is located within a first environment of the map for the video game, and obtaining a first environment equalizer profile associated with the first environment. Additional embodiments can include providing first instructions to the computing device associated with the first user according to the map equalizer profile and the first environment equalizer profile. The first instructions indicate to the computing device to adjust audio output of the video game according to the map equalizer profile and the first environment equalizer profile. Additional embodiments are disclosed.
US11666821B2 Thermo-haptics for a pointing device for gaming
An information handling system may include a processor, a data storage device, a power management unit, a thermo-haptic mouse, including an array of thermoelectric generators of a thermo-haptic module to selectively heat or cool a portion of the thermo-haptic mouse to be felt by a user of the thermo-haptic mouse, and a piezoelectric actuator of the thermo-haptic module to selectively apply a vibration to the portions of the thermo-haptic mouse to be felt by the user of the thermo-haptic mouse, and the processor executing code of a mouse training machine learning system to: receive, as training input, captured images during the execution of a gaming application and provide, as output, image recognition dataset descriptive of recognized game action event environmental data during execution of the gaming application, the image recognition dataset to be used by the processor executing a thermo-haptic feedback model evaluation system to provide thermo-haptic signals to the array of thermoelectric generators and the piezoelectric actuator to provide thermo-haptic feedback commensurate with the game action event environment during game play.
US11666819B2 RFID system for facilitating selections at a table game apparatus
Systems and methods for facilitating a card game on a table apparatus that comprises components (e.g., RFID antennas) for sensing wagering chips placed on the table provide for determining, based upon data from such components: (i) all losses to be collected by a dealer; (ii) all wins to be paid out by the dealer; and (iii) all commissions to be collected by the dealer. The systems and methods also facilitate outputting, on a dealer display device, an indication of one or more of the following for each player participating in the card game and based on the foregoing determinations: (i) a commission to be collected, if any; (ii) a losing wager to be collected, if any; and (iii) a win amount to be paid out, if any.
US11666816B1 Exercise machine accessory system
An exercise machine accessory system for facilitating exerciser rehydration during a workout and antibacterial machine wipe down. The exercise machine accessory system generally includes an exercise machine having a first end and a second end, first and second stationary exercise platforms, a movable carriage movably positioned upon a rail, a biasing member connected to the movable carriage, first and second handle assemblies connected to the frame of the exercise machine, a first bottle holder, a first antibacterial wipes dispenser and/or a first disposal receptacle connected to the first right handle assembly or the first left handle assembly.
US11666811B2 Swing measuring attachment, and swing measuring apparatus
A swing measuring attachment includes a base portion and a protrusion protruding from the base portion, in which the protrusion is provided with a screw thread, the protrusion including a projection at a front end of the protrusion.
US11666810B2 Putter including interchangeable sleeve mechanism capable of easily replacing and mounting shaft
Disclosed is a putter including an interchangeable sleeve mechanism capable of easily replacing and mounting a shaft, the putter comprising a main body part, a downward extension part, a blade formation part having a plate-shaped structure which extends to a predetermined length rearward from a lower end of the downward extension part and has an area having a predetermined size, a plurality of weight mounting grooves disposed to be spaced a certain interval from each other in an upper surface or a side surface of the blade formation part and configured to bind weights in a detachable structure, and a sleeve mechanism mounted in a structure detachably attached to the binding groove of the main body part, having a block structure extending to a predetermined height upward, and formed with a shaft binding fastening hole recessed to a predetermined depth in an upper end surface.
US11666807B2 Golf club
A golf club comprises a shaft, a golf club head fixed to one of ends of the shaft, and a grip attached to the other of the ends of the shaft and defining a grip end. The golf club head comprises a head main body and at least one weight. The head main body includes a plurality of ports for attaching the at least one weight. Each weight can be attached to and detached from each port so that the position of the center of gravity of the head can be changed by changing the position between the ports. The difference between a maximum value and a minimum value of linear distances from the grip end to the center of gravity of the weights when attached to the respective ports is not more than 20 mm.
US11666806B2 Golf club heads
Golf club heads are provided for selectively increasing or optimizing the coefficient of restitution (COR) at likely impact locations on the striking face of the golf club heads, while simultaneously maintaining characteristic time (CT) below a threshold value in those likely impact locations. By analyzing historical impact locations of a large cross-section of golfers, golf club head COR values can be increased or optimized in preferential locations on the striking face, such as using weighting factors for a predefined set of locations on the striking face. Therefore, instead of increasing COR uniformly across the face and/or increasing COR at impact locations on the face where golfers are unlikely to strike the golf ball, the sweet spot of the golf club head can be increased at the impact locations where golfers typically strike the golf ball.
US11666790B2 Chemically joined sprinkler assembly and fitting with internal reservoir
A sprinkler assembly includes a sprinkler body and a tubular connection fitting. The tubular connection fitting includes a first end for connection to a fluid supply pipe and a second end with the sprinkler body inserted therein, the tubular member including an outer surface and an inner surface defining an internal conduit extending along a longitudinal axis, the inner surface of the tubular member includes a first stop surface spaced from the first end to define an insertion depth for the fluid supply pipe and a second stop surface to limit insertion of the sprinkler body into the second end. The first stop surface defines an annular channel for housing an end of the fluid supply pipe.
US11666788B2 Wide-area fire-retardant system using distributed dense water fogger
A wide-area wildfire suppression system uses a network of geographically distributed water sprayers, and includes at least one wind sensor and a fire-suppression controller communicatively coupled to the water sprayers and the at least one wind sensor. The at least one wind sensor detects wind direction and communicates wind-direction information to the fire-suppression controller, which uses the wind-direction information to activate at least one of the water sprayers upwind of an asset or area to be protected. Parameters of the water spray, such as flow rate, droplet size, spray pattern, spray direction, spray elevation, or aeration, can be adapted based on wind direction or wind speed.
US11666787B2 Mask apparatus
A mask device includes a mask body provided with at least one inlet and at least one outlet located below the inlet, a first air cleaner and a second air cleaner for filtering outside air sucked in from an outside environment and supplying the filtered air through the mask body to the inlet, the first air cleaner coupled to one side of the mask body and the second air cleaner coupled to an other side of the mask body, and a first fixing part and a second fixing part, the first fixing part for coupling the first air cleaner to the mask body and the second fixing part for coupling the second air cleaner to the mask body.
US11666784B2 Surgical instruments
An ultrasonic surgical instrument is disclosed including an ultrasonic blade, an ultrasonic transducer operably coupled to the ultrasonic blade, and a control circuit. The ultrasonic transducer is configured to transmit ultrasonic vibrations to the ultrasonic blade based on a drive signal. The control circuit is configured to provide the drive signal to the ultrasonic transducer, monitor a vibration frequency of the drive signal, and modify the drive signal based on a change in the vibration frequency of the drive signal.
US11666783B2 Vascular marker for radiotherapy, radiotherapy assistance method, radiation irradiation control device, and vascular marker indwelling assistance device
A more accurate radiotherapy is implemented by using a vessel marker for radiotherapy having a deformation fixed shape for engaging with the inner wall of a vessel by deformation after being inserted into the vessel, and a position notification shape for notifying an outside of a radiation irradiation position. Also provided are a radiotherapy support method for supporting radiotherapy to be performed by using the vessel marker, a radiation irradiation control apparatus that irradiates, with radiation, a patient in which the vessel marker is indwelled, and a vessel marker indwelling support apparatus to be used when indwelling the vessel marker.
US11666782B2 Treatment planning for alpha particle radiotherapy
Apparatus for planning a diffusing alpha-emitter radiation therapy (DaRT) treatment session. The apparatus includes an output interface and a memory configured with a plurality of tables which provide an accumulated measure of radiation over a specific time period, due to one or more types of DaRT radiotherapy sources which emit daughter radionuclides from the source, for a plurality of different distances and angles relative to the DaRT radiotherapy source. In addition, a processor is configured to receive a description of a layout of a plurality of DaRT radiotherapy sources in a tumor, to calculate a radiation dose distribution in the tumor responsive to the layout, using the tables in the memory, and to output feedback for the treatment responsive to the radiation dose distribution, through the output interface.
US11666774B2 Pulse source and method for magnetically inductive nerve stimulation
The invention relates to a modular pulse source consisting of a main module and at least one additional module which are connected in series to each other in the sense of two-terminal circuits. The modules each comprise an energy storage device. The energy storage device of the main module is initially charged by a charging circuit. A stimulation coil is connected at the two ends of the series connection and as a result of a voltage pulse delivered by the chain of modules generates a magnetic field which in turn causes an induced electrical pulse or a respective electric field.
US11666773B2 Wearable cardioverter defibrillator (WCD) system using sensor modules with reassurance code for confirmation before shock
A wearable cardioverter defibrillator (“WCD”) system includes a support structure that can be worn by a patient, and a defibrillator coupled to the support structure. An ECG input, rendered from an ECG of the patient, may meet a primary shock criterion. One or more sensor modules are further provided, which are worn by the patient at different times. The sensor modules may monitor different physiological parameters of the patient, and transmit signals about them. The WCD system further has a multi-sensor interface to receive the transmitted signals, and a processor to determine from them whether a secondary shock criterion is met. If both the primary and the secondary shock criteria are met, the decision is to shock. The signals increase specificity of the detection, while the patient can wear different modules depending on context.
US11666771B2 Implantable electrical leads and associated delivery systems
Disclosed is a delivery system for a component, for example, a splitting lead. A splitting lead can have a proximal portion to engage a controller and a distal portion to split apart into sub-portions that travel in multiple directions during implantation into a patient. The delivery system can include a handle and a component advancer to advance and removably engage a portion of the component. The component advancer can be coupled to the handle and advance the component into the patient by applying a force to the portion in response to actuation of the handle by the operator. Also, the delivery system can include an insertion tip with first and second ramps to facilitate advancement of first and second sub-portions into the patient in first and second directions. The leads may have various electrode configurations including, for example, wrapped or embedded electrodes, helical or elliptical coils, thin metallic plates, etc.
US11666770B2 Implantable medical device for defibrillation of the heart based on the detection of mechanical vibrations
The present disclosure relates to an implantable medical device, in particular a cardiac defibrillator, comprising an implantable defibrillator configured to generate an electrical defibrillation signal, an implantable electrode connected with the implantable defibrillator by a lead and configured to deliver the electrical defibrillation signal to a patient, an implantable sensor configured to detect mechanical vibrations by the heart of the patient and to provide a detection signal based on the detected mechanical vibrations, and a controller configured to analyze the detection signal to determine at least one parameter characterizing the mechanical vibrations and to initiate a defibrillation operation of the implantable defibrillator based on the determined parameter characterizing the mechanical vibrations.
US11666764B2 System for measurement of impedance cardiography
The present invention relates to a system of multiple implantable medical devices for an impedance measurement comprising a first implantable medical device, at least a second implantable medical device distinct from the first implantable medical device and; an analysis module comprising at least one amplifier and one envelope detector, one of the first implantable medical device or the second implantable medical device being a subcutaneous implantable cardioverter defibrillator or a subcutaneous loop recorder, and the other of the first implantable medical device or the second implantable medical device being an implantable endocardial device.
US11666762B2 System implantable into the coronary venous network for the stimulation of a cardiac left cavity
This system includes a conductor microcable and an insulating microcatheter, including a hollow tube housing the microcable with the possibility of relative axial translation therebetween. The microcatheter is suitable for permanent implantation. The microcatheter, in its distal portion, includes at least one lateral window formed by a through orifice formed on the wall of the hollow tube. The window forms a stimulation site defined on the wall of the target vein facing the window of the microcatheter, and provides for a region of the microcable surface located at the window to form a stimulation electrode. In its distal portion, the microcable is not isolated at least in the region of the window of the microcatheter. The microcatheter is telescopically moveable on the microcable, so as to modify the position of the stimulation site of the target vein.
US11666761B2 Machine learning to optimize spinal cord stimulation
An example of a system may include a processor and a memory device comprising instructions, which when executed by the processor, cause the processor to: access a patient metric of a subject; use the patient metric as an input to a machine learning algorithm, the machine learning algorithm to search a plurality of neuromodulation parameter sets and to identify a candidate neuromodulation parameter set of the plurality of neuromodulation parameter sets, the candidate neuromodulation parameter set designed to produce a non-regular waveform that varies over a time domain and a space domain; and program a neuromodulator using the candidate neuromodulation parameter set to stimulate the subject.
US11666756B2 Method for controlling flow in a bodily organ
A method for treating a male impotent patient, the method comprising the steps of cutting the skin of the patient, inserting a dissecting tool and dissecting an area of at least one portion of a tissue wall of a penile portion, and placing a medical device. The medical device comprises a constriction device configured to gently constrict the penile portion to restrict the blood flow leaving the penis, and a stimulation device configured to stimulate the penile portion constricted by the constriction device to at least further restrict the blood flow leaving the penis to achieve erection.
US11666754B2 Apparatus and method of non-invasive directional tissue treatment
Some embodiments of the invention may be related to an apparatus for non-invasive directional tissue treatment. The apparatus includes a radiofrequency (RF) generator and an array of RF energy delivery elements in monopolar configuration, in active communication with the RF generator, at least one of: a return electrode and a return pad, and a power source and a controller. In some embodiments, each of the RF energy delivery elements comprises a monopolar electrode such that each monopolar electrode has a first dimension and a second dimension, the first dimension perpendicular to the second dimension. In some embodiments, the first dimension of each monopolar electrode and the distance between the monopolar electrodes in each pair are configured to create an elongated heated volume of tissue when the RF generator is activated and at least one of the RF delivery elements is in contact with the tissue.
US11666752B2 Leadless cardiac pacing devices
Implantable leadless pacing devices and medical device systems including an implantable leadless pacing device are disclosed. An example implantable leadless pacing device may include a pacing capsule. The pacing capsule may include a housing. The housing may have a proximal region and a distal region. A first electrode may be disposed along the distal region. One or more anchoring members may be coupled to the distal region. The anchoring members may each include a region with a compound curve.
US11666749B2 Implantable devices and methods for control of bacterial infections
An implantable antibacterial barrier device for an elongated medical device, the elongated medical device configured to extend from a first site, through a second site, to a third site. The implantable antibacterial barrier device includes a housing configured to be disposed at the first site, a working electrode configured to be disposed at the second site, and a reference electrode configured to be disposed at the first site. The housing includes barrier circuitry. The working electrode electrically is coupled to the barrier circuitry. The reference electrode is electrically coupled to the barrier circuitry. The barrier circuitry is configured to selectively maintain the working electrode at a negative electrical potential relative to the reference electrode to form an antibacterial barrier.
US11666748B2 Hybrid bearing seal for use in blood pump
A seal assembly is configured to seal a portion of a blood pump from the blood. The seal assembly includes a first seal; and a second seal. The second seal includes a lower contact-pressure seal than the first seal.
US11666745B2 Rotary valves for managing fluid flows in medical systems
In one aspect, a valve includes a valve body rotatable about a central axis of the valve body, an interior channel adjacent the valve body for permitting a fluid to flow through an axial opening of the interior channel, and a plug within the interior channel that is movable between a first axial position at the axial opening and a second axial position spaced apart from the axial opening. In the first axial position, the plug closes the axial opening to prevent the fluid from flowing through the axial opening in a first direction and to prevent the fluid from flowing through the axial opening in a second direction that is opposite to the first direction. In the second axial position, the plug permits the fluid to flow through the axial opening into the interior channel in the first direction.
US11666743B2 Valves
A valve comprising: a valve body; and a valve stem disposed at least partially within the valve body, the valve stem comprising a sidewall defining a central lumen and at least one opening in the sidewall, wherein the valve is adapted to prevent fluid flow through the lumen when the at least one opening is disposed within the valve body and permit fluid flow through the lumen when the at least one opening is exposed from the valve body, and wherein the valve is essentially free of a spring.
US11666740B2 Applicators for microneedles
An applicator for a microprojection array is described. In one embodiment, the applicator comprises an energy-storing element. Application of force causes the compressed energy-storing element to extend or transition from first and second configurations, releasing stored energy to deploy a holding member in the application which is configured to hold an array of microprojections. In another embodiment, the applicator comprises an energy storing element with two stable configurations, a first stable configuration and second stable configuration. Application of force causes the energy-storing element to transition from the higher energy first stable configuration to the lower energy second stable configuration, releasing the difference in energies of the two states to deploy a holding member in the application which is configured to hold an array of microprojections.
US11666733B2 Directional balloon transseptal insertion device for medical procedures with improved handle
The disclosed invention provides a handle for controlling movements of a transseptal insertion shaft which is suitable for facilitating precise and safe transseptal puncture of a cardiac interatrial septum, and a transseptal puncture system that include a transseptal insertion shaft and a handle to control movements of the transseptal insertion shaft. The handle includes two twister thread half shells, a nut inner and nut outer placed inside the two twister thread half shells, a first pull wire connected to a first side of the transseptal insertion shaft and coupled to the nut inner, a second pull wire connected to a second side of the transseptal insertion shaft and coupled to the nut outer. The nut inner and nut outer rotate in opposite directions to each other when the two twister thread half shells are turned in a direction.
US11666729B2 Methods of bonding components to polymeric substrates
Methods for bonding polymeric substrates to component parts, and medical devices assemblies including a tubing and a component part bonded together using a solvent containing a tackifier.
US11666725B2 Mask and components thereof
A patient interface includes a shell with a central opening configured to receive the pressurized flow of air, a foam cushion, and an elastomeric support portion that is attached to the shell, supports the foam cushion, and forms at least part of a chamber together with the shell and the foam cushion. The elastomeric support portion includes a side wall that forms a continuous perimeter around the chamber and a resiliently flexible lip that supports the foam cushion and extends from the side wall toward an interior of the chamber. The resiliently flexible lip has an outer perimeter that is anchored to the side wall and an unsupported inner perimeter. The foam cushion overhangs the inner perimeter of the resiliently flexible lip, and the shell is more rigid than the elastomeric support portion. In addition, the foam cushion is configured to directly contact and engage a portion of the patient's skin in use.
US11666724B2 Adjustable headgear tubing for a patient interface
Aspects of the present technology comprise a positioning and stabilising structure to hold a seal-forming structure in a therapeutically effective position on a head of a patient. The seal-forming structure may be constructed and arranged to form a seal with a region of the patients face surrounding an entrance to the patients airways for sealed delivery of a flow of air at a therapeutic pressure of at least 4 cmH2O with respect to ambient air pressure throughout the patients respiratory cycle in use. The positioning and stabilising structure may comprise a front hoop arranged to contact, in use, at least a region of the patients head superior to an otobasion superior of the patients head and a rear strap. The positioning and stabilising structure may comprise an adjustment mechanism for adjustment of the front hoop and the rear strap relative to the patients head, the adjustment mechanism being arranged in a single operation to adjust both the front hoop and rear strap to enable the positioning and stabilising structure to fit different size heads.
US11666723B2 Nasal cannula having improved and asymmetrical flow control
A nasal cannula includes a distribution conduit running along a virtual distribution path. The distribution path defines a longitudinal direction and has two branch openings. A respective supply conduit branches off from each branch opening. The distribution conduit also has two coupling openings arranged spaced apart from the branch openings. The nasal cannula has a plug via which one of the two coupling openings can be sealed as a closure opening. Another of the two coupling openings is designed as a supply opening. The plug has a flow-directing configuration with an exposed flow-directing surface. In a reference state in which the plug is closing the closure opening, the flow-directing surface is arranged in the distribution conduit in the longitudinal extension region of at least one branch opening and positioned relative to the distribution path to deflect treatment gas flowing in the distribution conduit from the supply opening along the distribution path towards at least one of the branch openings.
US11666716B2 System for automated adjustment of a pressure set by a ventilation device
A system for automated adjustment of a pressure set by a ventilation device, in particular a positive and-expiratory pressure and/or a maximum airway pressure, the system comprising a pressure detection arrangement for detecting a transpulmonary pressure at the end of an expiration phase and/or for detecting a transpulmonary pressure at the end of an inspiration phase, and a device for automated adjustment of the pressure set by the ventilation device on the basis of the transpulmonary pressure detected at the end of the expiration phase and/or the transpulmonary pressure detected at the end of the inspiration phase.
US11666713B2 Mist inhaler devices
A mist inhaler device (200) for generating a mist including a therapeutic for inhalation by a user. The device includes a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).
US11666712B2 Nebulizer and method for producing a nebulizer
The invention relates to a nebulizer (1) comprising an aerosol generator (6), a nebulizing chamber (5) and an outlet (16), the aerosol generator (6) being designed to release an aerosol into the nebulizing chamber (5) and the outlet (16) being designed to allow the removal of the aerosol from the nebulizing chamber (5). To achieve a high output rate, a wetting surface (2) is provided in the nebulizing chamber (5).
US11666709B2 Drive mechanism with noise reduction
A drive mechanism for a drug delivery device with a reduced operating loudness includes a dose selector, a housing, and a ratchet with a gear element comprising a plurality of gear teeth connected with the dose selector and a pawl element rotationally constrained to the housing comprising at least one pawl tooth. The at least one pawl tooth engages with the gear teeth and is located opposite to the gear teeth. One of the gear element and the pawl element moves forth and back relative to the other element of the gear and pawl elements along a first direction for de-engagement and re-engagement of the opposite gear teeth and at least one pawl tooth when the gear element rotates relative to the housing during dose setting using the dose selector. The pawl element and/or gear element comprises a noise reduction characteristic at a surface which dampens the noise produced.
US11666706B2 Syringe barrel and pre-filled syringe
A syringe barrel includes: a hollow body portion that is configured such that a gasket is slidably insertable therein. The syringe barrel is made of a resin that has a total light transmittance of 80% or more. A scale is disposed at an inner circumferential surface or an outer circumferential surface of the body portion, the scale being visible from an outside of the syringe barrel and being configured to indicate a liquid amount. The scale is formed by (i) a stepped structure having a step height in a range of 0.001 to 0.15 mm in a radial direction, and/or (ii) an embossment.
US11666704B2 Administration system, delivery device, and notification device for communicating status of a medical device
An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device can be a wearable automatic injector configured to be worn on the patient's skin. The delivery device of the present disclosure may allow a user or the patient to view a status of a container. For example, the delivery device of the present disclosure may provide a simple and effective visual means of displaying fill confirmation and delivery confirmation.
US11666695B2 Sub-atmospheric wound-care system
Methods and systems are provided for a sub-atmospheric wound-care (SAWS) system for treating an open wound. The SAWS system includes a regulated vacuum source for developing a negative pressure, a flow rate meter configured to measure a flow rate of liquid removed from the wound, a primary pressure regulating sensor located proximate the wound for directly measuring the negative pressure at the wound, a backup pressure regulating sensor located vacuum tube, a porous dressing suitable to be sealed airtight which is positioned within a wound interface chamber, a collection canister configured to collect said liquid removed from the wound, and an adapter configured to use wall suction a primary regulated vacuum source.
US11666694B2 Device for separation of fluid biological material, a separating float and a kit
The invention relates to a device for separation of fluidal biological material components, particularly separation of components of the material collected by liposuction for subsequent transfer of the adipose tissue in an injection form. The device comprises a container with an outlet duct arranged in it, the outlet duct having its upper end adapted for collecting the material, and its lower end that is in fluid communication with the inner space of the container at its bottom. Further, the invention relates to a separating float for separation of the fluidal biological material components, the float being intended to be used in the device, wherein the float comprises at least one by-pass opening for passage of the fluidal biological material contained in the container from the area below the separating float into the area above it. The invention also relates to a kit including the device and the float.
US11666693B2 Automated method for leukocyte collection from whole blood
The present invention relates to a method for separating lymphocytes and/or stem cells from whole blood in an automated blood separation system, wherein the quality of the collected lymphocytes and/or stem cells fractions is increased and the cell collection procedure is further automated by use of an optical sensor comprised in a detector device to measure turbidity and colour in the claimed method and in a cell separator, which can be used to perform the claimed method. The method of the invention is particularly useful to collect lymphocytes and/or stem cells fractions from whole blood, wherein the contamination of the collected cell fractions by platelets, red blood cells and granulocytes is reduced.
US11666689B2 Automated compression nursing and pumping system
A system for hands-free nursing and breast pumping includes a breast compression device with a plurality of thermoformed fluid bladders designed to fit adjustably against each breast and inflate and deflate with minimal power requirements. The compression device and its controller fit inside of a nursing garment designed to receive the device and controller for optimal compression. The nursing garment and the compression device have openings over the nipples so that a breast pump flange can be inserted through them and used in a typical manner for the extraction of breast milk, thus increasing the amount of milk expressed.
US11666687B2 Systems and methods for detecting an empty WB container
A system and method are provided for separating previously-collected whole blood into a red blood cell fraction and a plasma fraction by which the container of previously-collected whole blood is determined to be empty based on using the combination of the measured gross weight of the container and a calculated fluid flow rate from the container, based on weigh scale feedback. Upon detection of the empty container, flow from the container is stopped.
US11666686B2 Amtimicrobial silicones
A composition, comprising: a physiologically-acceptable polydimethylsiloxane having a surface; and one or more normal C6-C20NR1R2 saturated amine, salt thereof, or combination thereof, in contact with the polydimethylsiloxane, the surface, or both, wherein R1 and R2 may be same or different and independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, or combination thereof.
US11666682B2 Method of stopping CSF leaks and apparatus therefor
A method and kit for stopping cerebrospinal fluid (CSF) leaks, comprising penetrating and passing through a dural tissue an applicator to access an interior dural space, injecting from the applicator a fibrinogen-containing solution into said dural space, applying a sealing member containing a fibrinogen polymerizing agent onto an exterior surface of the dural tissue, and forming a polymerized fibrinogen or polymerized fibrin clot by contacting the injected fibrinogen-containing solution and the fibrinogen polymerizing agent.
US11666681B2 Abradable therapeutic coatings and devices including such coatings
A method of reducing surgical site infection (SSI), using a coated medical device having a tissue penetrating surface and an abradable coating on the medical device comprising at least one antimicrobial agent in the coating.
US11666678B2 Compact, mobile, modular, integrated diffuser apparatus and method
A new diffuser for essential oils and the like is rendered more compact by integrating the entire diffuser into a form of cap threaded to fit a bottle operating as a reservoir. The motor and pump system are integrated into a package sleeved inside a housing that then receives in a silo beside the pump and motor the entire reservoir and diffuser system. Simplified control algorithms provide a limited set of buttons that are more intuitive by which a user need only define total time of operation, some level of intensity of scent, and an indication of the comparative size of the space to be conditioned by the diffused scent.
US11666677B2 Device for evaporating volatile substances
The device for evaporating volatile substances comprises a casing (1) provided with a housing for the placement of a refill (2) containing the volatile substances, and is characterised in that said casing (1) comprises a surface (3) provided with at least one coupling element (5) in order to couple an additional element (4), said additional element comprising a frame (7) and a releasable sheet (8).It provides an evaporation device that can be easily customised.
US11666676B1 Aroma device for self-generating water vapor
The invention provides an aroma device for self-generating water vapor. The aroma device comprises a water vapor generator and an aroma body bearing portion. The water vapor generator is internally provided with a self-heating bag that is chemically reacted with water to generate high-temperature water vapor. Generated water vapor with aroma escapes outwards through an aroma carrier. The aroma device is convenient to carry and wide in diffusion range without a power supply. The high-temperature water vapor directly gasifies essence in a medium without generating other harmful dust and smog, and the aroma effect is remarkably enhanced.
US11666675B2 Challenge device for use with a measuring unit for testing steam sterilization efficiency and a method of manufacture of a challenge device
A challenge device for use with a measuring unit for testing steam sterilization efficiency, the challenge device comprising a measuring chamber, a first opening for insertion of a first temperature sensor of the measuring unit in the measuring chamber, and a second opening allowing air exchange between surroundings and the measuring chamber, where said air exchange is achieved by a hollow air flow passage. The measuring chamber is closed except for the first and second openings, and the air flow passage includes an outlet, which is located at a distance from the second opening in the direction of the length axis. The invention further relates to a method of manufacture of a challenge device.
US11666674B2 Light disinfection system and method
A lighting system includes a light source configured to generate light to inactivate one or more pathogens. The light includes an inactivating portion. In one embodiment, a method for inactivating one or more pathogens and optionally concurrently illuminating a room having one or more human occupants while the pathogens are inactivated is also provided. The method includes generating light from a light source to inactivate the one or more pathogens. The light is generated with an inactivating portion of the light.
US11666671B2 Spatial mapping of kidney functions
A molecular imaging agent including a detectable moiety, a chelation moiety, and a carrier moiety is provided. In one embodiment, the detectable moiety is coupled to the chelation moiety and the chelation moiety is linked to the carrier moiety. In another embodiment, the detectable moiety is 99mTc; the chelation moiety includes HYNIC; and the carrier moiety includes from N-terminus to C-terminus: a His6 purification tag, a human VEGFA polybasic tag sequence, and a human Fc stabilization segment.
US11666668B2 Masking and subsequently visualising ESR signals using the combination of two materials
A body has multiple phases, which have different electron spin resonance spectra that do not result from the simple combination of the ESR spectra of each individual phase.
US11666667B2 Patches comprising urushiol, test panels comprising the same, and methods of using the same
Disclosed herein are urushiol-containing epicutaneous patches comprising a support material and a urushiol-containing film on a surface of the support material. A surface of the support material is coated with the urushiol-containing film. Also described herein are test panels comprising urushiol-containing epicutaneous patches of varying urushiol content. The test panels can be employed in methods to assess subject sensitivity to urushiol, to determine a dose-response relationship to varying doses of urushiol, and to assess efficacy of treatments to prevent or inhibit urushiol-induced contact dermatitis in a subject.
US11666666B2 Methods and compositions for modifying a mutant dystrophin gene in a cell's genome
The present disclosure provides a method of modifying a mutant dystrophin gene in the genome of a cell. The present disclosure further provides compositions and kits for modifying a mutant dystrophin gene in the genome of a cell.
US11666663B2 Hexameric tetrahedral RNA nanostructures
Disclosed are nanostructures comprising a ribonucleic acid (RNA) scaffold comprising a hexameric tetrahedral core. The tetrahedral core may comprise four hexameric RNA nanorings linked together. Related pharmaceutical compositions, methods of modulating the expression of a target gene in a mammal, methods of treating or preventing a disease in a mammal, and methods of producing a hexameric tetrahedral RNA nanostructure are also disclosed.
US11666662B2 Silica-based biomolecule carrier, pharmaceutical composition comprising the same, preparation method and use thereof
Silica-based biomolecule carriers, compositions comprising the same and preparation methods and uses thereof for delivering biomolecules into a cell are provided. The silica-based biomolecule carrier comprises a porous core; a first bioactive moiety; a second bioactive moiety functionally associated with the first bioactive moiety; and linkers for respectively conjugating the first bioactive moiety and the second bioactive moiety to the porous core.
US11666658B2 Rifamycin analogs and antibody-drug conjugates thereof
The disclosure relates to rifamycin analog compounds, intermediates and precursors thereof, and pharmaceutical compositions capable of inhibiting bacterial growth (e.g., S. aureus growth) and treating bacterial infections (e.g., S. aureus infections). The disclosure further relates to antibody-drug conjugates of rifamycin analog compounds and antibodies, for example, antibodies specific for infectious disease-related targets such as membrane glycoprotein receptor (MSR1), wall teichoic acids (WTA) or Protein A, and methods of use thereof to inhibit bacterial growth and treat bacterial infections.
US11666657B2 Protein-drug conjugates and their use in the treatment of cancers
This invention pertains to protein-drug conjugates that may be used in the treatment of cancers and to pharmaceutical compositions containing the same. The protein-drug conjugate has the following formula (I), wherein: L is a cysteine-containing protein residue linked through one or more of the cysteine groups of the protein, R1 is selected from the group consisting of arylene, arylene-heteroarylene, heteroarylene-arylene and heteroarylene, n is an integer from 0 to 5, p and q are independently 0 or 1, R2, R3 and Z are spacers, u is 0 or 1 and T is a cleavable unit sensitive to hydrolases, k is 1 or 2 and D is a cytotoxic drug residue selected from dolastatin residues, which may be identical to or different from each other when k is 2, m is the mean payload-to-protein ratio (PPR) of the conjugate, which ranges from 0.1 to 16.
US11666656B2 Polymeric conjugates and uses thereof
Polymeric conjugates comprising a polymeric matrix having associated therewith an agent that down-regulates an activity or expression of a polypeptide associated with onset or progression of melanoma, and optionally and preferably, an additional agent that acts in synergy with said agent, are provided. Synthetic methodologies for preparing these conjugates and uses thereof in treating melanoma and other cancerous diseases are also provided.
US11666654B2 Drug delivery system for treating disease
The present invention relates to HPMA-CBz copolymers and methods for treating certain diseases comprising administering the copolymers to a subject in need thereof.
US11666642B2 PDE5 compositions and methods for immunotherapy
The present invention relates to compositions and methods for the regulated and controlled expression of proteins. Methods for inducing anti-cancer immune responses in a subject are also provided.
US11666639B2 Recovery dietary supplement
The present invention is directed to a method of replacing collagen broken down during physical activity using a novel dietary supplement. The supplement composition of the present invention comprises collagen, glutamine, taurine, and, optionally, the nine essential amino acids. The uptake of collagen is enhanced using this combination of components to levels substantially near the pre-workout levels.
US11666636B2 GLP-1R agonists and uses thereof
The present disclosure relates to glucagon-like peptide-1 receptor (GLP-1R) agonists and methods of treating or preventing allergic inflammation and/or methods of treating or preventing respiratory syncytial virus (RSV) infection.
US11666632B2 Pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist
A pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist, for example Ranibizumab, in a pre-filled pharmaceutical package, for example a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer. Stability performance of the VEGF-antagonist packaged in the coated COP vessel comparable to or better than glass was obtained.
US11666631B2 DPEP-1 binding compositions and methods of use
Pharmaceutical compositions and methods of their use are provided for reducing inflammation in a subject, blocking leukocyte recruitment, inhibiting tumor metastasis, treating sepsis and preventing/reducing acute kidney injury.
US11666630B2 Polypeptides for managing viral infections
Antiviral polypeptides and methods of use are provided herein. In particular, these polypeptides can comprise the Yodha amino acid sequence, variants, derivatives, or truncated versions thereof. In certain embodiments, this disclosure relates to uses of the peptides, nucleic acid molecules, and compositions disclosed herein to treat or prevent a viral infection.
US11666629B2 Peptide interacting with toll-like receptor 2 and the composition comprising the same
Disclosed herein are peptide fragments of Amuc_1100* and the use thereof. The peptide is shown to be a ligand to activate TLR2 and is used to treat obesity and the related disease or condition. The peptide of the present invention is further used in the treatment of intestinal cancer, promoting immune response, and intestinal epithelial barrier dysfunction.
US11666628B2 Compositions and method for the treatment of x-linked centronuclear myopathy
The present disclosure relates to a BIN1 protein or a BIN1 nucleic acid sequence producing or encoding the same, for a use in the treatment of X-linked centronuclear myopathy. The present invention provides compositions and methods for treatment of X-linked centronuclear myopathy. The present invention relates to a method of delivering the BIN1 polypeptide to subjects with X-linked centronuclear myopathy.
US11666624B2 Phage-peptide constructs for stimulating an immune response against CD47
Disclosed are recombinant bacteriophage constructs and related exogenous peptide sequences for generating immune responses against CD47. The disclosed recombinant phage constructs bind to antibodies against CD47 and can be administered to an animal to generate an immune response against CD47, including generating anti-CD47 antibodies. The disclosed recombinant phage may comprise an amino acid sequence of CD47, epitopic fragments, variants, or functional mimics thereof. Also disclosed are methods for making and selecting such recombinant phage constructs and compositions that comprise such constructs (e.g., compositions for inducing an immune response against CD47 including pharmaceutical or veterinary compositions used as vaccines). Also disclosed are recombinant polynucleotides comprising genomic nucleic acid of the recombinant phage constructs disclosed herein.
US11666622B2 Topical treatment for animals
A topical formulation and method of using the formulation on animals including dogs is disclosed. The formulation is used to facilitate the healing of cuts, scrapes, abrasions, and other conditions often experienced by animals. A main ingredient of the formulation is sulfur in a high concentration.
US11666620B2 Method for treatment of fine dust-caused skin cell damage, reinforcement of skin barrier, anti-aging, and anti-inflammation
The present specification discloses a composition for external application to skin, containing a tea plant root extract as an active ingredient, for treatment of skin damage caused by fine dust, whereby the expression level of one or more selected from a group consisting of IL-36G (NM_019618), S100A7 (NM_002963), S100A8 (NM_002964) and XDH (NM_000379), which are genes in skin cells the expression level of which is affected by fine dust, is regulated to a normal level.
US11666617B2 Treatment of warts
Disclosed herein are compositions having standardized potencies for use in the treatment of warts. Methods of treating a common wart comprising administering one or more intralesional injections of compositions having standardized potencies to a patient in need thereof are also disclosed. Further disclosed are methods of treating a non-common wart administering one or more intralesional injections of compositions having standardized potencies to a patient in need thereof.
US11666616B2 Use of photosynthetic scaffolds in tissue engineering
The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia.
US11666614B2 Probiotic bacteria isolated from wolves and related compositions and methods
Isolates strains of gastrointestinal bacteria from wolves are provided for use as probiotics. In some embodiments, the isolated strains are for use as probiotics in canine subjects such as domestic dogs. In some embodiments, the isolated strains may be used to treat or prevent intestinal dysbiosis in the subject. Also provided are compositions comprising at least one isolated strain of wolf probiotic bacteria and related methods for making same.
US11666613B2 Use of Lactobacillus paracasei subsp. paracasei K56 capable of regulating gastrointestinal flora balance
A new use of Lactobacillus paracasei subsp. paracasei K56 capable of regulating the gastrointestinal flora balance is described. The deposit number of the Lactobacillus paracasei subsp. paracasei is DSM27447. This strain alone has the ability to significantly promote the growth of intestinal Bifidobacterium and Lactobacillus, suppress Desulfovibrio and/or Enterobacteria in the intestine, suppress Helicobacter and/or Escherichia-Shigella, and can endure a simulated in vitro gastrointestinal fluid stress environment. Experiments in mice show that this strain has no acute oral toxicity, no antibiotic resistance, and may be safely used in food processing.
US11666612B2 Network-based microbial compositions and methods
Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
US11666611B2 Defined therapeutic microbiota and methods of use thereof
Described herein are methods and compositions for the use of treating and/or preventing Clostridium difficile infections, including recurrent C. difficile infections, in a subject. Aspects of the technology relate to administering to a subject in need thereof a composition comprising a defined therapeutic microbiota comprising, e.g. Clostridial species. Also described herein are biomarker profiles, including a biomarker profile comprising two groups of Clostridial species, that is predictive of the likelihood of recurrent C. difficile infection and/or susceptibility to initial C. difficile infection.
US11666599B2 Bromide source for use in treating autism spectral disorder
The present invention relates to a novel pharmaceutical use of bromide, i.e. the treatment of autism spectral disorder (ASD).
US11666598B2 Biomaterial comprising poly(itaconate-co-citrate-co-octanediol)
A method of treating infection and/or inflammation in a subject includes steps of providing a polyester biomaterial comprising diol monomers and at least first carboxylate monomers, wherein the first carboxylate monomers are itaconate; and administering the polyester biomaterial to the subject. The polyester biomaterial can be in the form of a biomimetic, and characterized by hydrolytic degradability. The polyester biomaterial may further include second carboxylate monomers. The biomaterial can be poly(itaconate-co-citrate-co-octanediol).
US11666594B2 Antibody-drug conjugates comprising a cyclic dinucleotide
The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases.The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
US11666593B2 Compositions containing adenosine triphosphate (ATP) and methods of use
The present invention provides a composition comprising adenosine or adenosine triphosphate (ATP) acting as an absorption enhancer when combined with a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug. Methods of administering ATP or adenosine to improve the bioavailability of a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug are described.
US11666592B2 Deoxynucleoside therapy for diseases caused by unbalanced nucleotide pools including mitochondrial DNA depletion syndromes
The invention relates generally to a pharmacological therapy for human genetic diseases, specifically those characterized by unbalance nucleotide pools, more specifically mitochondrial DNA depletion syndromes, and more specifically, thymidine kinase 2 (TK2) deficiency. The pharmacological therapy involves the administration of at least one deoxynucleoside, or mixtures thereof. For the treatment of TK2 deficiency, the pharmacological therapy involves the administration of either deoxythymidine (dT) or deoxycytidine (dC), or mixtures thereof. This administration of deoxynucleosides is applicable to other disorders of unbalanced nucleotide pools, especially those found in mitochondrial DNA depletion syndrome.
US11666590B2 Pharmaceutical composition, methods for treating and uses thereof
The present invention relates to certain SGLT-2 inhibitors for treating, preventing, protecting against and/or delaying the progression of chronic kidney disease in patients, for example patients with prediabetes, type 1 or type 2 diabetes mellitus.
US11666583B2 Methods of treating cortical dementia associated wandering
The invention is based on the discovery that rho kinase inhibitors can be used to treat certain dementia-associated wandering. The inventive methods relate to the use of rho kinase inhibitors in the treatment of patients with cortical dementia-associated wandering. Preferred aspects of the invention contemplate treating wandering due to cortical vascular dementia and wandering due to dementia where the patient is a persistent wanderer and/or where the patient does not display a wayfinding defect.
US11666571B2 Host defense protein (HDP) mimetics for prophylaxis and/or treatment of inflammatory diseases of the gastrointestinal tract
The present invention provides methods for treating and/or preventing inflammatory diseases of the gastrointestinal tract with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, and the use of compositions comprising the same.
US11666568B2 Pharmaceutical combinations comprising a histone deacetylase inhibitor and a BCL-2 inhibitor and methods of use thereof
The present disclosure relates to a pharmaceutical combination comprising (a) a histone deacetylase 6 inhibitor and (b) a BCL-2 inhibitor, including combined preparations and pharmaceutical compositions thereof; uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer in a subject comprising administering a therapeutically effective amount of such combination.
US11666564B2 Methods of treating Fabry patients having renal impairment
Provided are methods for treatment of Fabry disease in patients having HEK assay amenable mutations in α-galactosidase A. Certain methods comprise administering migalastat or a salt thereof every other day, such as administering about 150 mg of migalastat hydrochloride every other day.
US11666562B2 Ilaprazole for inhibiting the release of enveloped viruses from cells
Disclosed are methods and compositions for treating an infection by an enveloped virus in a patient in need thereof. The methods include administering to the patient a compound that inhibits or blocks release of the enveloped virus from an infected cell. As such, the disclosed methods include methods of inhibiting or blocking release of an enveloped virus from a cell. The disclosed methods may include administering to the patient a prazole-type compound having a substituted (pyridin-2-yl)methylsulfinyl-benzimidazole core.
US11666558B2 Methods of treating intraocular pressure with activators of Tie-2
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for eye conditions associated with angiogenesis, for example, intraocular pressure, ocular hypertension, and glaucoma.
US11666552B2 Method for modifying release of a therapeutically active agent from an elastomeric matrix
The present invention relates to a method for modifying release of a therapeutically active agent from an elastomeric matrix, comprising providing a core comprising an elastomeric matrix and a therapeutically active agent; dipping the core to a coating solution of an elastomer, wherein the elastomer comprises 20-35 wt-% of a filler, calculated from the total amount of filler and elastomer; curing the dipped core to provide a coated core. In this method the dipping is provided as a continuous process by pulling the core through the coating solution, using a pulling speed suitable for providing a coating thickness of δ-IOO the filler is selected from silica, titanium dioxide, barium sulphate, carbon and mixtures thereof; the elastomer comprised in the core and the elastomer comprised in the coating solution are independently selected from poly(dimethyl) siloxanes, polyethylene vinyl acetates (EVAs), polyurethanes (PUs), polyhydroxyethyl methacrylates (PHEMAs) and polymethyl methacrylates (PMMAs).
US11666547B2 Methods for treating cognitive deficits in a subject having schizophrenia, bipolar disorder, or psychiatric depression, and exhibiting cognitive deficits by administering an antagonist of the Na+-K+-2Cl-cation-chloride cotransporter isoform 1 (NKCC1)
Disclosed are methods for treating a psychiatric disease or disorder and/or symptoms thereof in a subject in need thereof, the method comprising administering to the subject an effective amount of an antagonist of the Na+-K+-2Cl— cation-chloride cotransporter isoform 1 (NKCC1) for treating the psychiatric disorder and/or the symptoms thereof in the subject. The methods further may include administering to the subject a dopamine D1 agonist and/or a GABAA agonist, optionally at a subeffective dose, where co-administering the antagonist of NKCC1 improves the efficacy of the dopamine D1 agonist and/or the GABAA agonist, optionally at the subeffective dose, for treating the psychiatric disease or disorder and/or symptoms thereof.
US11666545B2 Treatment or prevention of cardiovascular events via the administration of a colchicine derivative
A method for the treatment or prevention of a cardiovascular event in a subject with atherosclerotic vascular disease comprising the step of: b) administering a therapeutically effective amount of a compound of formula (I), a known colchicine derivative and/or a salt thereof wherein: R1, R2, R3, R4, R9, R10, R11 and R12 independently represent hydrogen, C1-4 alkyl, C2-4 alkenyl, C3-6 cycloalkyl, halogen, C1-4 haloalkyl, nitro, amino, C2-4 acylamino, C1-4 alkyl or dialkylamino, hydroxyl, C1-4 alkoxy, C1-4 alkylthio, a group of the formula —SO2N(Rx)2 or SO2Rx where Rx is C1-4 alkyl, C1-4 acyloxy, or optionally substituted phenyl, optionally substituted phenoxy; R7 and R8 independently represent hydrogen, C1-4 alkyl or C1-4 acyl; and R5′, R5″, R6′ and R6″ independently represent hydrogen, C1-4 alkyl, C2-4 alkenyl, C3-6 cycloalkyl, halogen, C1-4 haloalkyl, nitro, amino, C2-4 acylamino, hydroxyl, C1-4 alkoxy or C1-4 alkylthio a group of the formula —SO2N(Rx)2 or SO2Rx where Rx is C1-4 alkyl, C1-4 acyloxy, or optionally substituted phenyl.
US11666544B1 Compositions and methods for treating hypertension
Disclosed herein are compositions and methods for delivering cannabidiol to subject in need of hypertension treatment. The disclosed compositions are orally delivered. Further disclosed are kits comprising the disclosed compositions as part of a method of delivering the cannabidiol-containing compositions.
US11666543B1 Pharmaceutical compositions and methods for treating hypertension
Disclosed herein are compositions and methods for delivering cannabidiol to subject in need of hypertension treatment. The disclosed compositions are orally delivered. Further disclosed are kits comprising the disclosed compositions as part of a method of delivering the cannabidiol-containing compositions.
US11666541B2 Systems and methods for feeding sugar alcohol to ruminants during periods of heat stress
Systems and methods provide sugar alcohol to heat stressed ruminants to improve performance. During periods of high temperature or humidity, heat stressed ruminants may exhibit decreased dry matter intake, and in response, an effective amount of sugar alcohol such as sorbitol may be provided in the ruminant diet to cause performance to increase, which may include increased milk yield, improved feed efficiency or both compared to heat stressed dairy cattle without sugar alcohol in the diet.
US11666535B2 Curcuminoid composites
The present invention relates to a melt composite comprising one or more curcuminoids and a carrier selected from rice bran extract, mannitol, maltodextrin and mixtures thereof. The invention also provides a process for preparation of the melt composite, wherein the mixture of curcuminoids, rice bran extract, mannitol, maltodextrin and mixture thereof may be subjected to controlled conditions of heating and granulation. The melt composite may also be optionally comprised of one more excipient suitable for use for human consumption. Curcuminoid composites can be formulated in suitable solid, liquid or semisolid compositions. Curcuminoid composites and the compositions thereof, exhibit rapid dissolution and enhanced bioavailability.
US11666525B2 Topical skin care formulations comprising plant extracts
A method for treating skin of a person is disclosed. The method can include topically applying to the skin of the person a composition comprising an effective amount of an aqueous, alcoholic, or aqueous-alcoholic extract from Sequoia sempervirens, Geranium oil, panthenol, citric acid, and glycerin, wherein the composition increases antioxidant activity in the skin and/or increases skin moisture content.
US11666524B2 Personal-lubricating material and method for lubricant manufacture
The invention relates to a novel composition and method of manufacturing personal lubricant, commonly known as lube, to combine the most desirable features of disparate existing lube compositions to create a long lasting, oil-based, water soluble, non-toxic, anti-microbial, anti-yeast, non-staining, personal lubricant that can be organically sourced and will not damage commonly used prophylactics.
US11666523B2 Aqueous oral care fluoride treatment compositions, and methods
An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patients tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.5 wt-% to 4.8 wt-% of a water-soluble cationic N-containing polymer; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.
US11666521B2 Conditioning compositions containing cationic compounds, a silane compound and silica particles and methods for use
Disclosed are compositions for treating and conditioning keratinous substrates, comprising a silane compound; hydrophobic silica aerogel particles; a first organic acid; a cationic surfactant chosen from fatty dialkylamines; a second organic acid; a fatty alcohol; water; and optionally, a silicone compound other than the silane compound. Also disclosed are methods for treating and conditioning keratinous substrates using the composition.
US11666520B2 Hair growth composition and method
The present invention relates to compositions for and methods of retarding hair loss or facilitating hair growth comprising a hair growth active, a mixture of C12-C15 alkyl lactates and a viscosity modifying agent comprising at least one cellulose and/or a cellulose derivative. Clear compositions are also disclosed.
US11666516B2 Aqueous oral care thiocyanate-containing compositions, methods, and kits
An aqueous oral care one-part composition (e.g., solution), a kit that includes such composition (e.g., solution), and methods (e.g., a method of providing fluoride to a patients tooth surface), wherein the oral care composition (e.g., solution) includes: silver cations; thiocyanate anions; fluoride anions; and water.
US11666515B2 Phosphate crosslinked starch nanoparticle and dental treatments
A phosphorous compound such as STMP is used as a cross-linking agent while making a starch nanoparticle in an emulsion process. Negative charge of the nanoparticle is reduced or reversed by adding cations and/or cationizing the starch optionally while forming the nanoparticles. Anionic active agents, such as fluoride or fluorescein, are optionally incorporated into the nanoparticle during the formation process. For example, a fluoride salt can also be used, which promotes the crosslinking reaction while also providing fluoride in the nanoparticle. The retention of both calcium and fluoride in the nanoparticle is improved when both salts are used. Alternatively, the nanoparticle may be used without added calcium and/or fluoride. The nanoparticles may be useful for tooth remineralization, the treatment of dentinal hypersensitivity, to treat caries, or as a diagnostic agent to locate carious lesions.
US11666513B2 Medical pump
A medical pump, comprising: a fluid housing having a plurality of intake openings, sealed by at least one intake valve, and an outlet opening sealed by an outlet valve; a piston which is sealing the fluid housing and connected to a drive mechanism, the drive mechanism pulls the piston to draw fluid from one of the plurality of intake openings and pushes the piston to discharge the fluid into the outlet opening; and a selecting valve enclosing at least two tubes, each providing fluid to one of the plurality of intake openings, wherein the selecting valve closes one of the at least two tubes while opening another of the at least two tubes.
US11666507B2 Integrated resuscitation
An example of a CPR data recording system includes a hand-held chest compression measurement device and an external computing device communicatively coupled to the hand-held chest compression measurement device. The hand-held chest compression measurement device includes a housing, a motion sensor, a communication device, a memory disposed within the housing, and a processor disposed within the housing. The processor is configured to process a signal output from the motion sensor, calculate chest compression data from the processed signal output, evaluate the chest compression data after a delay from a start of the chest compressions to identify chest compressions that satisfy a pre-determined quality criterion, record the chest compression data in the memory, and send the recorded chest compression data to the external computing device via the communication device. The external computing device is configured to enable a review of the chest compression data.
US11666501B2 Devices and methods for assisting pronation and/or supination
Devices manipulate a hand of a user to provide pronation or supination assistance. Embodiments include an anchor; a hand engagement member operatively attached to the anchor and configured to receive and engage the hand of the user; a force applicator having a member portion and an anchor portion opposite the member portion, the force applicator attached to the hand engagement member proximate its member portion and attached to the anchor proximate its anchor portion; and a force application mechanism attached to the anchor and configured to cause a force to be applied to the force applicator causing the hand engagement member to manipulate the hand of the user to provide pronation or supination assistance. In some embodiments, the force application mechanism includes a non-incremental rotary mechanism. In some embodiments, a flexible tethering member attaches the anchor to the hand engagement member.
US11666498B2 Patient support apparatus with equipment weight log
A patient support apparatus, such as a bed, cot, stretcher, or the like, includes a litter frame, a support deck, a plurality of force sensors adapted to output signals corresponding to downward forces exerted on the support deck, and a controller configured carrying out various functions and to display various screens on a touchscreen or display, including a scale home screen and a scale equipment screen. A patient's current weight can be displayed on the scale home screen and the weight of equipment supported on the apparatus can be displayed on the scale home screen and the scale equipment screen. When a patient's current weight is characterized as possibly including non-patient weight, the controller can display a warning screen.
US11666493B2 Topsheets integrated with heterogenous mass layer
An absorbent article and method of making the absorbent article are disclosed. The absorbent article having a topsheet, a backsheet, and an absorbent core structure having one or more layers wherein at least one layer is a heterogeneous mass layer, wherein the topsheet and the heterogeneous mass are integrated such that they reside in the same X-Y plane.
US11666490B2 Medical systems, devices, and related methods
In one example, a medical system may comprise a delivery tube configured to couple to a vacuum source and provide negative pressure to a distal portion of the delivery tube; and a porous body at a distal portion of the delivery tube, the porous body including a first section and a second section removable from the first section.
US11666485B2 Adjustable mask
In an embodiment, a sleep mask is provided, which may include a site (such as a pocket near the center of the forehead), for holding electronical components for implementing a circadian rhythm disorder treatment program. Optionally, the sleep mask may also include one or more holes for locating and securing light pipes that are connected to lights for producing lighting that adjust a user's circadian pattern based on the circadian rhythm disorder treatment program. Optionally, the sleep mask also includes adjustable straps.
US11666483B2 System and method for angled optical access to the irido-corneal angle of the eye
A first optical subsystem includes a window with a refractive index nw and an exit lens having a refractive index nx. The exit lens is configured to couple to the window to define a first optical axis extending through the window and the exit lens. A second optical subsystem is configured to output a light beam. The light beam is directed to be incident at a convex surface of the exit lens along a second optical axis at an angle α that is offset from the first optical axis. The window is configured to detachably couple to the cornea of the eye such that the first optical axis is generally aligned with a direction of view of the eye. The respective refractive indices nw and nx are configured to direct the light beam incident at the convex surface of the exit lens through the cornea of the eye toward the irido-corneal angle.
US11666482B2 Personalization of excimer laser fibers
The invention provides personalized laser probes for use in laser systems, wherein each laser probe includes one or more characteristics tailored to a given user to thereby improve performance of and outcome of a laser treatment procedure.
US11666478B2 Maxillary devices, controller station, and methods of treating and/or diagnosing medical disorders
Maxillary devices and Mandibular devices each have a first housing connectable to a tooth of a user or connectable or integral with a teeth covering, wherein the housing encloses an on-board circuit board and a power source. The first housing of the maxillary devices has a tooth connecting portion, a palate housing portion and/or a buccal housing portion. The first housing of the mandibular devices has a tooth connecting portion and a sublingual portion. Each of the palate housing portion and the buccal housing portion enclose a stimulator having an electrode electrically connected to the on-board circuit board and the power source, and can enclose a sensor and/or a medicament dispenser. The sublingual portion encloses a sensor and a medicament dispenser each of which are in electrical communication with the microprocessor of the on-board circuit board.
US11666476B2 Method and device for the treatment of obstructive sleep apnea and snoring
The device relates to methods and devices for the treatment of obstmctive sleep apnea syndrome.
US11666474B2 Female urinary device
An external female urinary device includes a connecting and urine collecting component (CUCC) and a urine directing and discharging component (UDCC) configured to connect with the CUCC. The CUCC tapers from a larger orifice to a smaller orifice. The CUCC has a ring defining the larger orifice. The ring is made of a material capable of adhering to urethral orifice surrounding skin (UOSS) as well as to the inner facing surfaces of the labia minora and/or the labia majora after the CUCC is pressed against that UOSS. The ring remains adhered to the UOSS without requiring an external force for keeping the ring in contact with that skin.
US11666471B2 Walking boot, chafe assembly, protective rim for a push-button release valve and related methods
A walking brace is provided. The walking brace includes a U-shaped malleable stay configured to hold a manually-bent shape. The walking brace includes an integral portion. The integral portion includes a footbed, a first upright disposed at a first side of the footbed and a second upright disposed on a second side of the footbed. The integral portion is overmolded onto the U-shaped malleable stay such that the U-shaped malleable stay extends through each of the footbed, the first upright and the second upright. Other walking braces are provided wherein the integral portion includes a pocket configured to receive the U-shaped malleable stay at an underside of the integral portion such that the U-shaped malleable stay extends through each of the footbed, the first upright and the second upright. A method of manufacturing a walking brace is also provided.
US11666470B2 Pyloric anchor retrieval tools and methods
A retrieval device comprising a hook assembly and a capsule assembly. The hook assembly has an attachment feature at a first end. The capsule assembly includes a capsule, a capsule shaft, and a handle connected in series and defining an inner bore. The capsule has a first end defining an opening. The inner bore of the capsule assembly is configured to slidably receive the hook assembly. The handle has a central portion, a first extension portion attached to the capsule shaft, and a second extension portion with a hook assembly lock at a second end. The hook assembly lock is configured to lock the hook assembly to the second extension portion. The second extension portion is configured to pull the hook assembly relative to the capsule shaft, and the first extension portion is configured to push the capsule shaft relative to the hook assembly along the central longitudinal axis.
US11666467B2 Hemostasis valve and delivery systems
A stent graft delivery system for delivering an aortic prosthetic device includes a handle, an internal lead screw assembly within a track of a handle body of the handle, a lead screw nut that extends about the handle body and threadable engaged with the threaded portion of the internal lead screw assembly, a support member fixed to the handle body, a sheath extending about a portion of the support member and fixed to the internal lead screw assembly, and a hemostasis valve about the supporting member and between the sheath and the lead screw assembly.
US11666465B2 Vascular stenting for aneurysms
Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatus for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allows adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen-demanding tissues, are not deprived of the necessary blood flow.
US11666457B2 Expandable fusion device and method of installation thereof
The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes a body portion, a first endplate, and a second endplate, the first and second endplates capable of being moved in a direction away from the body portion into an expanded configuration or capable of being moved towards the body portion into an unexpanded configuration. The fusion device is capable of being deployed and installed in both configurations.
US11666455B2 Bone graft delivery devices, systems and kits
A bone graft delivery kit includes a hollow tube having a proximal end and a distal end. The hollow tube is configured to convey graft material to a graft receiving area in a patient. The hollow tube can be connected to an implant. The kit further includes a plunger to facilitate moving the graft material through the hollow tube.
US11666454B2 Surgical plate systems
Improved bone plate systems are described herein. In some instances, a bone plate system can include a base plate, at least one retainer plate, and at least one spacer. The at least one retainer plate is configured to reside on the base plate in a free floating manner and can receive at least one fastener to secure the retainer plate to the at least one spacer, thereby providing a plate system that attaches to a spacer. In other instances, a bone plate system can include a base plate having one or more push plates that can engage at least one spacer.
US11666453B2 Porous surgical implant and method of making same
A surgical implant and a method for the making the surgical implant is provided. The surgical implant includes various granules incorporated into an upper surface and a lower surface of a body portion thereof. The granules can be pressed into the upper surface and the lower surface via physical force using at least one mold portion. The physical force applied by the at least one mold portion can deform and/or extrude the upper surface and the lower surface to impregnate these surfaces with the granules. The granules can provide the implant with bioresorbable and/or mechanically-reinforced properties.
US11666451B2 Bio-mechanically compatible 3D-printed intervertebral disc
An artificial replacement disk assembly comprised of a core in between two endplates. The endplates have outer surfaces that match the surface morphologies of the corresponding vertebral endplates. The endplates may have textured inner surface to form a strong fusion with the core during the fabrication process. The thick solid endplates strongly fused to the core create a very resilient implant. Gripping structures on the endplates may permit easy manipulation of the assembly during surgical procedures.
US11666445B2 Customized load-bearing and bioactive functionally-graded implant for treatment of osteonecrosis
An engineered medical device for treatment of osteonecrosis is provided where the size, porosity and ceramic content of the device can be personalized based on an individual patient's anatomical and physiological condition. The device distinguishes different segments mimicking anatomically-relevant cortical and cancellous segments, in which the cortical segments of the device can sustain mechanical loading, and the cancellous segment of the device can promote bone ingrowth, osteogenesis and angiogenesis.
US11666442B2 Techniques for facilitating heart valve tethering and chord replacement
A method is described, for use with a native valve of a heart of a subject, the valve being disposed between an atrium and a ventricle of the heart. A first radiopaque marker and a second radiopaque marker are percutaneously advanced to the heart. The first radiopaque marker is placed against a tissue site in the ventricle. The second radiopaque marker is placed against a leaflet of the valve. A distance is measured between the first radiopaque marker at the tissue site, and the second radiopaque marker at the leaflet. Responsively to the measured distance, a chord-length is determined. An artificial chord, selected based on the chord-length, is implanted in the heart. Other embodiments are also described.
US11666440B2 Intracardiac device to correct mitral regurgitation
A device structured to suppress mitral regurgitation by restricting prolapse of a mitral valve leaflet and including a base correspondingly dimensioned to the mitral valve and including a central portion, structured to allow blood flow there through and a peripheral portion or ring connected to the central portion in substantially surrounding relation thereto. An operative position of the base includes the central portion disposed in overlying, movement restricting relation to at least one of the valve leaflets and the ring concurrently anchored adjacent or directly to the native annulus of the mitral valve. The physical characteristics of the base facilitate its movement with and conformance to the mitral valve during diastole and systole cycles of the heart.
US11666436B2 System and method for crimping a prosthetic valve
A device for crimping a radially expandable and collapsible prosthetic valve comprises a crimping loop having a first end portion, a second end portion, and a loop portion extending between the first and second end portions and defining an opening configured to receive the prosthetic valve. The crimping loop is movable between a first state in which the opening has a first diameter and a second state in which the opening has a second diameter smaller than the first diameter such that when the prosthetic valve is positioned within the loop portion, movement of the crimping loop from the first state to the second state is effective to reduce a diameter of the prosthetic valve. A method for crimping a prosthetic valve comprises reducing a diameter of an opening of a crimping loop, thereby radially compressing an at least partially expanded prosthetic valve disposed within the opening.
US11666433B2 Double orifice device for transcatheter mitral valve replacement
Valve devices for replacement of mitral valves while preserving valvular and subvalvular mitral valve apparatus. The valve device may be configured as a double orifice valve replacement device, and may include an anchoring and manifold assembly coupleable to a delivery catheter. The assembly may include means for anchoring the device to the mitral valve or to a fixation device already attached to the mitral valve. A peripheral ring anchoring system secured to the assembly may include at least one expandable anchoring ring that is expandable within an orifice of the mitral valve so as to surround the orifice perimeter. A helical suture may be helically disposable about the ring, securing the ring to adjacent leaflet tissue. A trap door valve including a trap door body that seals against the anchoring ring during systole and unseals during the diastolic portion of the cardiac cycle may be provided.
US11666431B2 Overdrive prevention for expandable anchor
Surgical devices and methods are provided for anchoring tissue to bone, and more particularly methods and devices are provided for preventing over-insertion of an expander into a sheath of a two-piece anchor. For example, a tendon anchoring system is provided with an anchor assembly and an inserter tool. The anchor assembly includes a sheath with a threaded lumen and a threaded expander screw configured to be threadably disposed within the sheath to cause the sheath to expand outward. The inserter tool includes an elongate outer shaft with a distal end configured to couple to a proximal end of the sheath, and an elongate inner shaft with a distal drive tip configured to engage a proximal end of the expander screw. In one embodiment, the inner shaft can be rotatable relative to the outer shaft to thread the expander screw into the sheath, and the inner shaft can be prevented from rotating relative to the outer shaft when the expander screw is fully threaded into the sheath to prevent over-insertion of the expander screw into the sheath.
US11666430B2 Systems and methods for adjusting the diameter of an endoluminal prosthesis and an endoluminal prosthesis configured for the same
Systems and methods of adjusting the diameter of an endoluminal prosthesis that allows for controlled radial deployment of the endoluminal prosthesis and the ability to revise the positioning of the endoluminal prosthesis after unsheathing. The endoluminal prosthesis includes a stent graft having a tubular graft wall, a stent, a main strand, a proximal strand, and a distal strand.
US11666427B2 Portable simultaneous tooth polishing and bleaching system using a full-contact swinging mechanism
A portable tooth polishing and bleaching treatment system is provided for simultaneous tooth surface polishing and bleaching for use at home or in dental clinics. A full contact swinging mechanism is employed to transfer a continuously rotational input from a motor into a back-and-forth swinging movement output. The system comprises an electrically powered handpiece, a detachable swinging angle, a rubber cup, a user-specific thermoplastic gum protector, and a dual-agent mixing set consisting of a separated storage of polishing bleaching agents and an agent mixing tool. The swinging angle alone is used as a prophylaxis angle for dental clinics.
US11666426B2 Brush attachment, electric toothbrush handpiece and electric toothbrush comprising the electric toothbrush handpiece and the brush attachment
A brush attachment for a toothbrush handpiece, in particular for an electric toothbrush handpiece, has a head portion which includes a brush head, has an attachment portion which includes an interface receptacle, and has a neck portion arranged between the head portion and the attachment portion, wherein the interface receptacle is implemented by a universal interface receptacle for receiving at least two different interfaces of different toothbrush handpieces.
US11666423B2 Dental implant replica for a dental model manufactured with 3D additive technology
The present invention of a digital dental implant replica for a dental model manufactured with 3D additive technology and a system relates to a digital dental implant replica to simulate the position of the dental implant in a dental model which has been produced by means of 3D printing processes or CAD/CAM systems, providing greater precision and maneuverability with respect to analog systems in the orientation of the implant in the dental model due to a simple retention system which is easy to use and detachable.
US11666422B2 CBCT imaging of impression having implant locator
Embodiments provide the capability to determine a digital 3D model of a patient's teeth obtains projection images acquired by scanning a negative impression of the patient's teeth using a computed tomographic imaging apparatus, where the impression includes a radio-opaque transfer element for a dental implant or crown post. One exemplary method reconstructs, from the projection images, an air volume model within the reconstructed volume and bounded by a transition surface defined according to the negative impression. A transfer element volume model of the transfer element is defined, segmented from the air volume model and from the transition surface. A combined digital 3D model of the patient's teeth is formed according to the air volume model and transfer element volume model. At least a portion of the combined digital 3D model of the teeth is displayed.
US11666417B2 Method for analysing a dental situation
A method for analyzing a real dental situation of a patient. The method includes steps, as follows, in succession. At an updated instant, acquisition of an updated image representing a real dental scene as observed by an operator. Determination of a virtual dental scene as a function of the representation of the real dental scene on the updated image. Presentation of the virtual dental scene in transparent mode and overlaid on the real dental scene, or display of the updated image on a screen and presentation of the virtual dental scene overlaid with the representation of the real dental scene on the updated image displayed on the screen, in transparent mode or not on the representation.
US11666416B2 Methods for simulating orthodontic treatment
Methods for simulating orthodontic treatment are provided. In some embodiments, a method includes capturing a first representation, the first representation including a depiction of a patient's teeth. The method can include building a parametric model of the patient's teeth based on the first representation, using one or more case-specific parameters for one or more shapes associated with at least one of the patient's teeth. The method can also include simulating an outcome of a dental treatment plan for the patient's teeth to produce a simulated outcome of the dental treatment plan. The method can further include modifying the parametric model to provide a modified model representing the simulated outcome of the dental treatment plan.
US11666408B2 Tray for temporary storage of catheters and other coiled surgical devices
A storage tray provides storage for multiple types of wires, catheters, and other instruments used during surgical procedures. The storage tray includes a base and a set of walls forming a basin that holds liquid. A wire containment section within the basin holds multiple coiled guidewires in a channel filled with the liquid. The wire containment section includes an inner wall and one or more wall segments forming an outer boundary of the channel. A wire holder outside the channel holds end portions of the guidewires. Pulling an end portion of one of the coiled guidewires horizontally causes the guidewire to slide along the inner wall for separation and removal from the storage tray.
US11666404B2 Articulating including antagonistic controls for articulation and calibration
A surgical tool includes a drive housing, a shaft extending from the drive housing, an end effector at an end of the shaft and having opposing jaws and a cutting element, and an articulable wrist configured to rotate the end effector within a plane. The wrist is articulated via antagonistic translation of a pair of drive members. Various systems are provided for homing one or more drive inputs that cause movement in the wrist and/or the end effector, or for controlling articulation of the drive inputs.
US11666398B2 Flexible medical instrument
A system comprises a flexible instrument, a first user input device spaced from the flexible instrument, and a second user input device including a first state and a second state. The system further comprises a control system configured to, based on an input received from the first user input device, control an orientation of the flexible instrument. The control system is further configured to, based on an input received from the second user input device, adjust a stiffness of the flexible instrument. The stiffness of the flexible instrument is lower when the second user input device is in the first state than when the second user input device is in the second state.
US11666388B2 Method and system for computer assisted surgery
A method and system for computer assisted orthopedic feedback of at least one surgical object relative a pre-operative plan are disclosed. The pre-operative plan includes a virtual object, which is the virtual representation of the surgical object, and a virtual structure, which is the virtual representation of the patient structure. The method comprises providing the pre-operative plan including planned position and orientation of the virtual object relative to of the virtual structure; obtaining the position of the patient structure based on a surface of the patient structure using a surgical navigation system; obtaining the position of the surgical object using the surgical navigation system; registering the patient structure to the virtual structure and the surgical object to the virtual object; tracking a current position and orientation of the surgical object using the surgical navigation system; and providing feedback of a current position and orientation of the surgical object relative to the planned position and orientation of the virtual object based on the tracked current position and orientation of the surgical object.
US11666384B2 Prediction of postoperative global sagittal alignment based on full-body musculoskeletal modeling and posture optimization
A system for surgical planning and assessment of spinal pathology or spinal deformity correction in a subject, the system comprises a control unit configured to align one or more vertebral bodies of a biomechanical model to one or more vertebral bodies of the radiograph. The control unit is configured to receive one or more spinal correction inputs. The control unit is configured to, based on the received one or more spinal correction inputs, simulate the biomechanical model in a predetermined posture. The control unit is configured to provide for display one or more characteristics of the simulated biomechanical model.
US11666383B2 Systems and methods for intraocular lens selection
Systems and methods for intraocular lens selection include obtaining one or more pre-operative measurements of an eye; selecting, from a plurality of historical IOL implantation records, a subset of historical IOL implantation records for evaluating a first plurality of prediction model candidates; evaluating the first plurality of prediction model candidates; selecting a first prediction model from the first plurality of prediction model candidates based on the evaluating; calculating, using the selected first prediction model, a plurality of estimated post-operative MRSE values based on a set of IOL powers and the one or more pre-operative measurements of the eye; determining a first IOL power corresponding to a first estimated post-operative MRSE value that matches a predetermined post-operative MRSE value; and providing the determined first IOL power to a user to aid in selection of an IOL for implantation in the eye.
US11666380B2 Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation related application
Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.
US11666378B2 Systems and methods for therapeutic nasal neuromodulation
The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.
US11666374B2 Medical instrument with jaw with friction-coupled drive cable
An electrically energized medical instrument uses one or more drive cables to both actuate mechanical components of a wrist mechanism or an effector and to electrically energize the effector. Electrical isolation can be achieved using an insulating main tube through which drive cables extend from a backend mechanism to the effector, an insulating end cover that leaves only the desired portions of the effector exposed, and one or more seals to prevent electrically conductive liquid from entering the main tube. Component count and cost may be further reduced using a pair of pulleys that are shared by four drive cables.
US11666373B2 Treatment system and energy treatment tool
A treatment system includes an energy treatment tool and a power supply device. The energy treatment tool includes respective first and second grasps configured to be coupled with one another and are capable of pivoting with respect to one another so as to grip a treatment target therebetween. A plurality of bipolar electrodes is attached to the respective first and second grasps. The plurality of bipolar electrodes receives a high-frequency current to flow through the treatment target so as to develop a first temperature distribution in the treatment target. A treatment energy source is configured to be coupled to one of the respective first and second grasps and receives electric energy to generate treatment energy different from the high-frequency current and to apply the generated treatment energy to the treatment target so as to develop a second temperature distribution in the treatment target.
US11666369B2 Multifunctional ablation device
An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.
US11666368B2 Method for constructing and using a modular surgical energy system with multiple devices
A method for constructing a modular surgical system is disclosed. The method comprises providing a header module comprising a first power backplane segment, providing a surgical module comprising a second power backplane segment, assembling the header module and the surgical module to electrically couple the first power backplane segment and the second power backplane segment to each other to form a power backplane, and applying power to the surgical module through the power backplane.
US11666366B2 Systems and methods for vertebral or other bone structure height restoration and stabilization
A system for restoring height of a vertebral body with a balloon and stabilizing the vertebral body with bone cement. A delivery tube extends from a handle and may be formed from a flexible polymer and a radiopaque filler. The flexible polymer maintains a patent lumen along a curve so as to receive sequential introduction of the balloon and the bone cement to within the vertebral body at a location offset from a longitudinal axis. The radiopaque filler provides for at least a portion of the delivery tube being radiopaque under fluoroscopic visualization. The radiopaque filler may be barium, and the delivery tube may be constructed from coextruding the flexible polymer with the barium. Visual indicia on the handle may indicate a position of the delivery tube relative to another component of the system such as an access cannula. The visual indicia may indicate a direction of the curve.
US11666365B2 Staple and plate hard tissue fixation
A hard tissue fixation staple-plate interlocking device can include a recess in a staple body or a plate. The device can also include a locking part of the other of the staple body or plate. The device can be reconfigurable between an insertion configuration and an interlocked configuration. In the insertion configuration, the locking part can slide into the recess in a translation sliding motion that is parallel to a sliding motion of the legs of the staple, as the legs of the staple slide through the holes in the plate. In the interlocked configuration, the locking part can be at least partially in the recess, and recess surface portions can engage part surface portions and inhibit movement of the staple and plate out of the interlocked configuration. Also, multiple staples and screws can be interlocked with the plate, with staples being at non-parallel angles to each other.
US11666360B2 Tool(s) for inserting a glaucoma shunt
A glaucoma treatment system includes a glaucoma drainage device having a flexible tube with distal and proximal ends, and an inserter with a filament that extends beyond the distal end of a rigid elongate member (e.g., rod or inserter tube). The filament is configured to detachably couple a distal portion of the drainage device tube to the elongate member of the inserter. The filament may extend through a wall of the distal portion of the drainage device tube. The filament and elongate member of the inserter can be configured for relative movement to detach the drainage device tube from the inserter. The elongate member can define an internal channel, and the filament can be configured for axial movement in this channel so that the filament may move toward the proximal end of the elongate member to detach the drainage device tube from the inserter. Other tools are described and claimed.
US11666358B2 Jacket flexible needle assembly
The present teachings relate generally to a medical flexible needle assembly (10), comprising a needle portion (20) disposed at a distal end (12) of the assembly; a stiff portion (30) disposed at a proximal end 14 of the assembly; an flexible portion disposed between and interconnecting the needle portion and the stiff portion, including a flex distal portion (42), a flex proximal portion (44); and a jacketing member (50) disposed about the assembly (10) over at least part of the flexible portion (40); characterized in that the jacketing member (50) includes one or more coupled regions (60) and one or more decoupled region (70), wherein in at least one or more of the one or more coupled regions (60) are located proximally, distally, or both of the flexible portion (40).
US11666348B2 Intracorporeal expandable shock wave reflector
An intracorporeal pressure shock wave includes an expandable pressure shock wave reflector at the distal end of an intracorporeal catheter to direct shock waves from a shock wave generator within a human or animal blood vessel or body lumen.
US11666347B2 Surgical retractor and resection guide
A surgical instrumentation system for a shoulder arthroplasty that includes a retractor that includes a curved section structured to wrap around and substantially engage a posterior portion of a humeral head, an alignment guide extending from the retractor. The alignment guide includes a primary alignment shaft and a resection guide attachable to the retractor, the resection guide including a guide surface for guiding a cutting tool.
US11666342B2 Surgical clip applier with wide aperture surgical clips
An end effector for a surgical clip applier includes an elongate body, first and second jaw members extending out a distal end of the body, and a clip track provided within the body and containing one or more surgical clips, each surgical clip including a crown and a pair of legs extending longitudinally from the crown and diverging from each other at a diverging opening angle. A pre-forming region is defined by the first and second jaw members to receive and deform the one or more surgical clips from a first state, where the pair of legs diverge at the diverging opening angle, and a second state, where the diverging opening angle is minimized and the one or more surgical clips are prepared to be received by the first and second jaw members and crimped.
US11666333B2 Adapter assemblies for interconnecting surgical loading units and handle assemblies
An adapter assembly includes an elongated body, a switch, a sensor link, and an annular member. The elongated body includes a proximal portion configured to couple to a handle assembly and a distal portion configured to couple to a surgical loading unit. The switch is configured to be toggled in response to the surgical loading unit being coupled to the distal portion of the adapter assembly. The sensor link is disposed within the distal portion of the adapter assembly and biased toward a distal position. The sensor link is longitudinally movable between a proximal position and the distal position. The annular member is disposed within the distal portion and is rotatable between a first orientation, in which the annular member prevents distal movement of the sensor link, and a second orientation, in which the sensor link moves distally to toggle the switch.
US11666332B2 Surgical instrument comprising a control circuit configured to adjust the operation of a motor
A surgical instrument comprising a housing, a shaft, an end-effector, a cutting member, and a control circuit is disclosed. The housing comprises a motor. The end-effector comprises a first jaw, a second jaw movable relative to the first jaw, an anvil, and a staple cartridge comprising staples, driver elements, and a sled configured to eject the staples toward the anvil. The sled is movable between a proximal unfired position and a distal fired position through a firing stroke. The cutting member is configured to be advanced distally into the sled by the motor. The control circuit is configured to detect the location of the cutting member, monitor a parameter indicative of a load experienced by the cutting member, determine a threshold value of the parameter based on a portion of the firing stroke, and adjust operation of the motor if the monitored parameter exceeds the determined threshold value.
US11666331B2 Systems for detecting proximity of surgical end effector to cancerous tissue
A surgical instrument includes an end effector having a first jaw, a second jaw movable relative to the first jaw to grasp tissue therebetween, an anvil, a staple cartridge comprising staples deployable into the tissue, wherein the staples are deformable by the anvil, and a sensor configured to provide a sensor signal according to a physiological parameter of the tissue. The surgical instrument further includes a control circuit coupled to the sensor, wherein the control circuit is configured to receive the sensor signal, and assess proximity of the sensor to cancerous tissue based on the sensor signal.
US11666323B1 Soft anchors having increased engagement between deployment sutures and sleeve
A soft anchor having a sleeve, being a circular braided suture defining a lumen, and defining a first terminus, having a first terminus opening and a second terminus having a second terminus opening. Also, a deployment suture is engaged to the sleeve by extending into the lumen through a first broach point, then out of the sleeve through the first terminus opening, then into the sleeve through a second broach point, on the bottom-side, and then out of the lumen though a third broach point, then into the lumen through the second terminus opening and out of the suture though a fourth broach point, thereby creating a first lateral trap, between the first broach point and the first terminus opening, a second lateral trap, between the second terminal opening and the fourth broach point, and a central trap, between the second and third broach points.
US11666322B2 Method of forming a suture-button-graft combination and facilitating construct
A suture and button construct, having an oblong button defining at least a first aperture and a second aperture; a suture length, including a braid defining a lumen and having a middle section and two end sections, each extending through a button aperture and both terminating in an end. Both ends have a needle attached. Also, two shuttles are engaged to the suture length, each having a free end and a loop end, terminating in a loop. Each shuttle enters the lumen in the middle section and extend through an aperture, while in the lumen and exit on the opposite button side from the middle section, so that both shuttle loops are available outside the lumen, to pull a suture end through the lumen and a button aperture.
US11666320B2 Fixation members, assemblies, and related systems and methods
A suture anchor for fixation within an anatomical structure includes an actuation member in contact with an anchor body at a first location thereof. The anchor body is elongate along a direction of elongation and defines a central axis. In a neutral configuration, the anchor body is flat and defines a thickness along a transverse direction and a width along a lateral direction, the width being greater than the thickness. The anchor body has first and second tails that are braided together along a portion of the actuation member from the first location to a second location of the anchor body. The actuation member is configured to apply a force to the braided anchor body so as to actuate the anchor body in a manner increasing its maximum thickness along a second direction that is angularly offset from the direction of elongation.
US11666319B2 System for meniscal repair using suture implant cinch construct
A system for repairing tears in soft tissue, e.g., meniscal tissue, by employing cinch stitching. More specifically, the present invention provides an apparatus for meniscal repair using a suture implant construct. The suture implant construct includes a first and second implant which are connected to each other via a length of suture. The implants are designed to be loaded on external surfaces of the first and second trocars.
US11666318B2 Distraction device with disposable force sensor pod
A surgical system includes a disposable force sensor pod that includes a load cell and a mounting feature. The surgical system also includes a computing system configured to be placed in electronic communication with the disposable force sensor pod and receive a force measurement from the disposable force sensor pod. The disposable force sensor pod is configured to be removeably coupled to a distraction device using the mounting feature.
US11666317B2 Sternal ascender apparatus
A sternal elevator apparatus is disclosed. The sternal elevator may include a panel, a support beam traversing the panel, and a post coupled to a proximal end of the panel. The apparatus may also include an indicator handle coupled to the sternal elevator, an actuator drive pivotably coupled to the indicator handle, and a housing movably coupled to the actuator drive. The sternal elevator apparatus may have an actuator drive incorporating a linear rack. The housing further may include a cylindrical gear where the cylindrical gear is engaged with the linear rack.
US11666316B2 Weighted surgical retractor systems
This document provides surgical retractor devices and systems. For example, this document provides a weighted surgical retractor system. In one example embodiment, this document provides a weighted Deaver retractor system that includes a selectable amount of weight that can be releasably coupled to a shaft of the retractor. The surgical retractors provided herein can be used during a variety of surgical procedures, including surgical procedures performed on the abdomen, thoracic regions, limbs, and so on. In some embodiments, the surgical retractors provided herein are well-suited for retraction of the vaginal canal for hysterectomy surgery, and for other procedures for which vaginal retraction is necessary.
US11666314B2 Method and apparatus for closing a hole in cardiac tissue
Aspects of the present invention provide apparatuses and methods for closing an apical hole in a heart of a subject, including a hole-closure device that includes a tissue-attachment portion configured to attach to cardiac tissue around the apical hole, and a collapsible portion coupled to the tissue-attachment portion and configured to close the hole by collapsing inwardly inside the apical hole.
US11666310B2 Ultrasound diagnostic apparatus and method for controlling ultrasound diagnostic apparatus using predetermined imaging conditions for B-mode image generation
An ultrasound diagnostic apparatus includes an ultrasound probe and an imaging unit that transmits and receives an ultrasound beam to and from a subject using the ultrasound probe and converts a received signal output from the ultrasound probe into an image to generate an ultrasound image of the subject, according to set imaging conditions. The ultrasound diagnostic apparatus further includes a probe state determination unit that determines whether the ultrasound probe is in an aerial emission state or a contact state with the subject; and an apparatus control unit that changes the imaging conditions in a case in which the probe state determination unit determines that the ultrasound probe has been changed from the contact state with the subject to the aerial emission state and controls the imaging unit such that the ultrasound image is generated using the changed imaging conditions.
US11666307B2 Devices, systems, and methods for real-time monitoring of fluid flow in an anuerysm
Embodiments of the present disclosure are configured to assess effectiveness of an endovascular aneurysm coiling procedure. A system is provided that can include a flow-sensing intravascular device with a flexible elongate member which is sized and shaped for insertion into a vasculature, and a flow sensing element secured to a distal portion of the flexible elongate member. A computer can be in communication with the flow-sensing intravascular device. With a coil is positioned within an aneurysm, the computer can detect a flow measurement of fluid entering the aneurysm based on data obtained by the flow sensing element positioned within the aneurysm, and can determine that the fluid flow measurement is at or below an acceptable level. If flow is at an unacceptable level, additional coils can be added to further restrict flow. Also, a second source of fluid into the aneurysm can be indicated by the flow measurements.
US11666306B2 Device and method for detecting misuse of a medical imaging system
The present invention relates to a device (10) for detecting a misuse of a medical imaging system (20), comprising a data interface (12) for acquiring medical image data (24) and audit log data (26) from the medical imaging system (20); a processing unit (14) which is configured to configured to analyse the medical image data (24) to determine whether or not a part of a fetus is imaged in the medical image data (24), to compare the medical image data (24) and the audit log data (26) with each other, and to determine based on said comparison whether there is a mismatch between the medical image data (24) and the audit log data (26); and a feedback unit (16) which is configured to generate a misuse alert signal if a mismatch is detected by the processing unit (14).
US11666302B2 One-piece diaphragm and ring for stethoscope chestpiece
A one-piece diaphragm and ring for a stethoscope chestpiece is disclosed herein. The one-piece diaphragm and ring includes a diaphragm portion having a flat disk shape; and a ring portion connected to an outer periphery of the diaphragm portion, the ring portion being integrally formed with the diaphragm portion, and the ring portion configured to be attached to a rim of a chestpiece body portion. A chestpiece of a stethoscope that includes the one-piece diaphragm and ring is also disclosed herein.
US11666300B2 Method for the real-time control of exposure to an X-ray dose
A method for the real-time control of exposure to an X-ray dose emitted by a generator tube for generating an X-ray beam and received by a detector includes a flat panel detector, comprising a set of pixels organized into a matrix along rows and columns and configured so as to generate signals on the basis of the X-ray dose impinging on the detector, the generator tube comprising a control unit for controlling the generator tube that is configured so as to control an emitted X-ray dose, the control method comprising the following steps: exposing the flat panel detector to an X-ray dose emitted by the generator tube for generating an X-ray beam; repeatedly reading out at least one of the rows of pixels while the flat panel detector is exposed to the X-ray dose; determining a payload signal and a stray signal based on the signals from the readout of the at least one of the rows; transmitting the payload signal to the control unit for controlling the generator tube.