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US11634829B2 |
Method for producing aluminum alloys
The invention relates to production of alloys based on aluminum. A method is proposed for producing aluminum-based alloys by electrolysis, according to which low-consumable anode of aluminum pot is used as a source of alloying elements. At the same time, in order to optimize master alloy consumption, one of the following options is chosen: dissolution of alloying elements from slightly soluble anodes; adding oxides and/or fluorides and/or carbonates of alloying elements to electrolyte melt of aluminum pot; simultaneous dissolution of alloying elements from slightly soluble anodes with addition of oxides and/or fluorides and/or carbonates of alloying elements to electrolyte melt of aluminum pot. The method comprises the following stages: introducing alloying elements into molten cathode aluminum by dissolving them in electrolyte melt of aluminum pot from low-consumable anode and/or by adding oxides/and fluorides and/or carbonates of alloying elements into electrolyte melt of aluminum pot; reduction of alloying elements introduced into electrolyte melt of aluminum pot on molten cathode aluminum to form the base for aluminum alloys; determining percentage of elements in the base for aluminum alloys; and bringing alloys to a given composition by adding alloying elements to the base for aluminum alloys in the required amount. The result is multicomponent aluminum alloys of a given composition with introduction of alloying admixtures in the process of aluminum production by electrolysis, and then the alloy is brought to a predetermined composition, providing simplification of technology and control, reducing master alloy consumption which leads to lower cost of aluminum alloy production. |
US11634823B2 |
Structurally altered gas molecule produced from water and method of generation thereof
A structurally altered gas molecule. The structurally altered gas molecule is a combination of two parts of hydrogen and one part of oxygen and produced from water by placing an electrolyte solution in a chemical reaction chamber, adding purified water to the chemical reaction chamber, and applying a focused magnetic field generated by earth magnets and an electric field to a mixture of the purified water and the electrolyte solution to cause generation of the structurally altered gas molecule from the purified water. A temperature in the chemical reaction chamber is from 60 degrees to 120 degrees in Fahrenheit. A pressure in the chemical reaction chamber is from 1 atmosphere to 40 pounds per square inch gauge (psig). The structurally altered gas molecule has a hydrogen-oxygen-hydrogen bond angles between 94 degrees and 104 degrees and hydrogen-oxygen bond length between 0.95 Angstrom and 1.3 Angstrom. |
US11634821B2 |
Method for manufacturing film for decoration element
The present disclosure relates to a method for manufacturing a film for a decoration element, the method including depositing two or more islands on one surface of a film; and forming a pattern portion by dry etching the film using the island as a mask. |
US11634818B2 |
Solution composition containing trivalent chromium for surface treatment of steel sheet, galvanized steel sheet surface—treated with same, and method for manufacturing galvanized
A surface treatment solution composition for forming an inorganic film, comprising: 10 to 30% by weight of a trivalent chromium compound containing chromium phosphate (A) and chromium nitrate (B) and satisfying a content ratio A/(A+B) of 0.3 to 0.6; 5 to 50% by weight of a silane compound; 0.2 to 3% by weight of a vanadium-based rust-inhibiting and corrosion-resisting agent; 0.5 to 5% by weight of a cobalt-based rust-inhibiting and corrosion-resisting agent; and 12 to 84.3% by weight of water, an alloyed hot-dip galvanized steel sheet surface-treated using the composition, and a method for manufacturing the alloyed hot-dip galvanized steel sheet, are provided, and the surface treatment solution composition containing the trivalent chromium compound has an excellent effect on corrosion resistance, blackening resistance, fuel resistance, weldability, and alkali resistance. |
US11634814B2 |
Atomic layer deposition apparatus
An atomic layer deposition apparatus having a vacuum chamber, a deposition chamber within the vacuum chamber, an inlet channel extending from outside of the vacuum chamber to the deposition chamber such that the inlet channel is connected to the deposition chamber for supplying gases to the deposition chamber, a discharge channel extending from the deposition chamber to outside of the vacuum chamber for discharging gases from the deposition chamber, one or more first precursor supply sources connected to the inlet channel, and one or more second precursor supply sources connected to the inlet channel. The vacuum chamber is arranged between the one or more first precursor supply sources and the one or more second precursor supply sources. |
US11634813B2 |
Half-angle nozzle
Embodiments of the present disclosure provide apparatuses for improving gas distribution during thermal processing. In one or more embodiments, an apparatus includes a body, an angled gas source assembly, and a gas injection channel. The gas injection channel has a first half-angle and a second half-angle. The first half-angle is different from the second half-angle. The use of an improved side gas assembly in a processing chamber to direct gas from the center toward the edge of the substrate advantageously controls growth uniformity throughout the substrate. Surprisingly, directing gas through a gas channel with non-uniform half-angles will significantly increase the reaction at or near the edge of the substrate, thereby leading to an improved overall thickness uniformity of the substrate. |
US11634807B2 |
Zinc-plated steel sheet for hot stamping and production method therefor
A zinc-plated steel sheet for hot stamping according to an aspect of the present invention includes a steel substrate and a plated layer provided on a surface of the steel substrate, in which the steel substrate contains, in % by mass, C: 0.10 to 0.5%, Si: 0.7 to 2.5%, Mn: 1.0 to 3%, and Al: 0.01 to 0.5%, with the balance being iron and inevitable impurities, and the steel substrate has, in the inside thereof, an internal oxide layer consists of an oxide containing at least one of Si and Mn having a thickness of 1 μm or more, and a decarburized layer having a thickness of 20 μm or less from an interface with the plated layer toward an internal direction of the steel substrate. |
US11634805B2 |
Austenitic stainless steel and reactor internal structure
An austenitic stainless steel includes a mixed grain structure composed of a columnar crystal having an average crystal grain size of 20 μm or less and an equiaxed crystal having an average crystal grain size of 5.0 μm or less, in which an area proportion of the columnar crystal in the mixed grain structure is 20% or more, and an average crystal grain size of the whole mixed grain structure is 5.0 μm or less. Accordingly, it is possible to provide a material having excellent irradiation resistance and mechanical properties. |
US11634804B2 |
Austenitic stainless steel weld joint
Provided is an austenitic stainless steel weld joint that is excellent in polythionic acid SCC resistance and naphthenic acid corrosion resistance, and is also excellent in creep ductility. An austenitic stainless steel weld joint includes a base material and a weld metal. The weld metal has a chemical composition at its width-center position and at its thickness-center position consisting of, in mass %, C: 0.050% or less, Si: 0.01 to 1.00%, Mn: 0.01 to 3.00%, P: 0.030% or less, S: 0.015% or less, Cr: 15.0 to 25.0%, Ni: 20.0 to 70.0%, Mo: 1.30 to 10.00%, Nb: 0.05 to 3.00%, N: 0.150% or less, and B: 0.0050% or less, with the balance: Fe and impurities. |
US11634803B2 |
Quench and temper corrosion resistant steel alloy and method for producing the alloy
A quench and temper steel alloy is disclosed having the following composition in weight percent. C0.1-0.4 Mn0.1-1.0 Si0.1-1.2 Cr9.0-12.5 Ni3.0-4.3 Mo 1-2 Cu0.1-1.0 Co 1-4 W 0.2 max. V0.1-0.6 Ti 0.1 max. Nbup to 0.01 Taup to 0.01 Al 0-0.25 N0.1-0.35 Ce0.006 max. La0.006 max. The balance of the alloy is iron and the usual impurities found in similar grades of quench and temper steels intended for similar use or service, including not more than about 0.01% phosphorus and not more than about 0.010% sulfur. A quenched and tempered steel article made from this alloy is also disclosed. Further disclosed is a method of making the alloy. |
US11634802B2 |
Cold-rolled steel sheet
The cold-rolled steel sheet having a high bake hardening amount and excellent bendability after bake hardening according to the present invention has a predetermined composition, and contains 20% or more and 70% or less of ferrite and 30% or more of tempered martensite in terms of area ratio, in which a sum of ferrite and tempered martensite is 90% or more, and in a case where a microstructure image of 30 μm×30 μm obtained by photographing a structure at a magnification of 2,000-fold is disposed in an xy coordinate system having a sheet thickness direction as an x-axis and a rolling direction as a y-axis, the microstructure image is divided into 1024 pieces in an x-axis direction and 1024 pieces in a y-axis direction to form 1024×1024 divided regions, and a two-dimensional image is created by performing double gradation by assuming a value of “1” in each of the divided regions in one case where the structure is ferrite and assuming a value of “0” in the other cases, a heterogeneity α when two-dimensional discrete Fourier transform is performed on the two-dimensional image is 1.20 or less. |
US11634791B2 |
Coated steel product
A hot-dip coated steel product including: a steel product; and a coating layer including a Zn—Al—Mg alloy layer disposed on a surface of the steel product, in which the Zn—Al—Mg alloy layer includes a Zn phase, an Al phase, and a MgZn2 phase, and contains a Mg—Sn intermetallic compound phase in the Zn phase, and the coating layer has a chemical composition satisfying a predetermined average composition, a total area proportion of the Al phase and the MgZn2 phase is 70% or more, an area proportion of the Zn phase is 30% or less, an average value of cumulative circumferential lengths of the Al phase is less than 88 mm/mm2, and a total frequency in number of the Al phase having a circumferential length of 50 μm or more is less than 100. |
US11634784B2 |
Ultra-thick steel material having excellent surface part NRL-DWT properties and method for manufacturing same
Disclosed are a high-strength ultra-thick steel material and a method for manufacturing same. The high-strength ultra-thick steel material comprises in weight % 0.04-0.1% of C, 1.2-2.0% of Mn, 0.2-0.9% of Ni, 0.005-0.04% of Nb, 0.005-0.03% of Ti and 0.1-0.4% of Cu, 100 ppm or less of P and 40 ppm or less of S with a balance of Fe, and inevitable impurities, and comprises, in a subsurface area up to t/10 (t hereafter being referred to as the thickness of the steel material), polygonal ferrite of 50 area % or greater (including 100 area %) and bainite of 50 area % or less (including 0 area %) as microstructures. |
US11634782B2 |
Quantification of microorganisms in samples and methods of determining quantification conditions thereof
This disclosure relates to methods of determining quantification conditions for a microorganism and methods of quantifying microorganism concentration in a sample. |
US11634781B2 |
Fecal sample processing and analysis comprising detection of blood
A method of processing a fecal sample from a human subject comprising removing a portion of a collected fecal sample and adding the removed portion of the sample to a buffer that prevents denaturation or degradation of blood proteins found in the sample, and detecting the presence of human blood in the removed portion of the fecal sample. The method further comprises stabilizing the remaining portion of the fecal sample. |
US11634778B2 |
Kit, device, and method for detecting lung cancer
This application provides a kit or a device for detection of lung cancer, comprising a nucleic acid(s) for detecting a miRNA(s) in a sample from a subject, and a method for detecting lung cancer, comprising measuring the miRNA(s) in vitro. |
US11634775B2 |
Circulating serum microRNA biomarkers and methods for Alzheimer's disease diagnosis
Biomarkers and methods for identifying, verifying and confirming circulating serum-based microRNAs. The microRNAs (PARKmiRs) can be used to differentiate patient's suffering from Alzheimer's disease (AD) from non-AD patients. |
US11634774B2 |
Genome-wide capture of inter-transposable element segments for genomic sequence analysis of human DNA samples with microbial contamination
A method for identifying one or more genomic variations in human genomic DNA, comprising employment of Alu, MIR and SVA sequence-based PCR primers and performing an inter-transposable-element (ITE) polymerase chain reaction on the assay mixture to produce an array of amplicons comprising the ITE genomic segments. Also provided the use of the method for identifying one or more genomic variants associated with a trait or a disease. |
US11634765B2 |
Methods and compositions for paired end sequencing using a single surface primer
The present disclosure is concerned with compositions and methods for the paired-end sequencing of target nucleic acids, and more particularly to obtaining nucleotide sequence information from two separate regions of target nucleic acids using amplification sites having a single type of surface primer. |
US11634764B2 |
MSP nanopores and related methods
Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression. |
US11634763B2 |
Enzyme method
The invention relates to a new method of characterizing a target polynucleotide. The method uses a pore and a Hel308 helicase or amolecular motor which is capable of binding to the target polynucleotide at an internal nucleotide. The helicase or molecular motor controls the movement of the target polynucleotide through the pore. |
US11634757B2 |
Emulsions with improved stability
The present invention relates to an emulsion, preferably a water-in-oil emulsion. comprising: a continuous phase comprising a conductivity improving compound, a dispersed phase suspended in the continuous phase, and a surfactant. The present invention also relates to a population of droplets comprising an aqueous phase, dispersed in a continuous oily phase comprising an oil and a conductivity-improving compound. The present invention also relates to a microfluidic chip comprising a hydrophobic composition comprising an oil, a surfactant and a conductivity improving compound in an injection chamber configured so that injecting a hydroplilic composition through said injection means will generate an emulsion in the injection chamber; and to a kit comprising a microfluidic chip and a container comprising an aqueous composition. The present invention also relates to a process for manufacturing an emulsion according to the invention. The present invention also provides methods for analyzing biological material, for example for analyzing biological material within the emulsion of the invention. |
US11634749B2 |
Cartridge for the detection of methylated DNA
The present invention is based on the discovery of sensitive and specific methylation detection by a) controlling excessive DNA degradation prior to conversion by incubating DNA conversion reagent (e.g. bisulfite reagent) directly with a nucleic acid containing sample without requiring prior nucleic acid purification from the sample and without requiring prior nucleic acid denaturation at elevated temperatures of 98° C. and, b) optimizing bisulfite removal by controlling the pumping rate flow of the bisulfite treated sample over an extraction membrane inside an automated system. In some embodiments, a cartridge for the detection of methylated DNA is provided. |
US11634748B2 |
Methods for the epigenetic analysis of DNA, particularly cell-free DNA
Methods are provided for the epigenetic analysis of cell-free DNA using organic boranes to convert oxidized 5-methylcytosine residues in the cell-free DNA to dihydrouracil (DHU) residues. Cell-free DNA is contacted with an organic borane selected to successively bring about reduction, deamination, and decarboxylation of oxidized 5-methylcytosine residues such as 5-carboxymethylcytosine and 5-formylcytosine, resulting in DHU residues in place thereof. Following amplification, the treated cell-free DNA is sequenced, with the DHU residues read as thymine residues. Reaction mixtures, kits and additional methods are also provided, as are related methods for the epigenetic analysis of DNA, including cell-free DNA. |
US11634743B2 |
Coupled, self-sufficient biotransformation of chenodeoxcholic acid to ursodeoxycholic acid and novel enzyme mutants applicable in said process
The present invention relates to a coupled biotransformation process of converting chenodeoxycholic acid (CDCA) and related compounds to ursodeoxycholic acid (UDCA) and related compounds. It also relates to the cloning, expression, and biochemical characterization of a novel NADP+-dependent 7α-hydroxysteroid dehydrogenase (7α-HSDH) from Clostridium difficile, cofactor switch mutants thereof, and their application for the oxidation of bile acids. A further aspect of the invention relates to novel NADP-dependent cofactor switch mutants of the NADP+-dependent 7α-HSDH of E. coli and their application for the oxidation of bile acids. |
US11634740B2 |
Allulose epimerase variant, method for preparing the same, and method for preparing allulose using the same
The present invention provides: a novel allulose epimerase variant in which an amino acid residue present at a specific position of an amino acid sequence of a wild-type D-allulose 3-epimerase derived from Flavonifractor plautii is substituted with another amino acid residue; and various uses of the novel allulose epimerase variant. The novel allulose epimerase variant according to the present invention has a higher conversion rate of fructose to allulose compared to that of the wild-type D-allulose 3-epimerase derived from Flavonifractor plautii, and has excellent thermal stability especially under high temperature conditions of 60° C. or higher, and thus can prevent contamination during an industrial-scale enzymatic conversion reaction for the mass production of allulose, shorten production time, and reduce production costs. |
US11634734B2 |
Limiting yeast-produced trehalose in fermentation
The present disclosure relates to recombinant yeast host cells having (i) a first genetic modification for reducing the production of one or more native enzymes that function to produce glycerol or regulating glycerol synthesis and/or allowing the production of an heterologous glucoamylase and (ii) a second genetic modification for reducing the production of one or more native enzymes that function to produce trehalose or regulating trehalose synthesis and/or allowing the expression of an heterologous trehalase. The recombinant yeast host cells can be used to limit the production of (yeast-produced) trehalose (particularly extracellular trehalose) during fermentation and, in some embodiments, can increase the production of a fermentation product (such as, for example, ethanol). |
US11634733B2 |
Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
Genetically engineered hosts and methods for their production and use in synthesizing hydrocarbons are provided. |
US11634730B2 |
Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms. |
US11634727B2 |
Recombinant nucleic acid molecule of transcriptional circular RNA and its application in protein expression
The present disclosure relates to a recombinant nucleic acid molecule of the transcriptional circular RNA and its application in protein expression. Specifically, the present disclosure relates to a recombinant nucleic acid molecule of the transcriptional circular RNA, recombinant expression vector, pre-circularized RNA, circular RNA, recombinant host cell, pharmaceutical composition and protein preparing method. The transcription product of the recombinant nucleic acid molecule in this present disclosure is a circular RNA which containing specific IRES element. IRES element can increase the protein expression level of circular RNA in eukaryotic cells, achieve efficient and persistent expression of protein. It has important application value in many fields like: Preparation of mRNA infectious disease vaccines, therapeutic mRNA tumor vaccines, mRNA-based dendritic cell tumor vaccines, mRNA-based gene therapy, mRNA-based chimeric antigen receptor T cell therapy, and protein supplement therapy. |
US11634725B2 |
Methods and compositions for plant pathogen resistance in plants
The disclosure relates to a plant that is tolerant or resistant to species of Ca. Liberibacter. Specifically exemplified are citrus and solanaceous plants. Provided by the disclosure is a modified citrus or solanaceous plant that is resistant or tolerant to Sec-dependent effectors secreted by bacteria. Also provided by the disclosure are methods of modifying a plant genome plant to provide tolerance or resistance to species of Ca. Liberibacter. Still further provided by the disclosure are methods conferring a population of plants with tolerance or resistance to species of Ca. Liberibacter and screening that population for the plants that are tolerant or resistant to species of Ca. Liberibacter. |
US11634724B2 |
Composition and methods for producing tobacco plants and products having reduced tobacco-specific nitrosamines (TSNAs)
The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs. |
US11634723B2 |
Promoter, promoter control elements, and combinations, and uses thereof
The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels. |
US11634722B2 |
Plant gene editing systems, methods, and compositions
Systems, methods, and compositions that provide for increased frequencies of plant gene editing in comparison to controls are provided herein. Also disclosed are compositions that provide for editing target genes in plant cells. Systems for modification of a plant genome and/or target plant gene are provided. Methods for modifying a plant cell genome or a target plant gene in a plant cell genome are also provided. Compositions, plant cell cultures, and/or reaction mixtures comprising plant cells, certain agents, and gene editing molecules are also provided herein. |
US11634721B2 |
Reconstruction of site specific nuclease binding sites
Disclosed herein are methods and compositions for the repair of site specific nuclease binding sites by targeted integration and/or targeted excision of one or more sequences into a cell. |
US11634716B2 |
Genetically modified mesenchymal stem cells for use in cardiovascular prosthetics
A cardiovascular graft is provided, such as a prosthetic heart valve or blood vessel, that comprises mesenchymal stem cells (MSCs) and/or progeny thereof, modified to knock down or knockout expression of the telomerases reverse transcriptase gene (TERT), or otherwise reduce activity of TERT. Also provided are a method of making the cardiovascular graft, and a method of implanting the cardiovascular graft. |
US11634714B2 |
Oligonucleotide comprising an inosine for treating DMD
The invention provides an oligonucleotide comprising an inosine, and/or a nucleotide containing a base able to form a wobble base pair or a functional equivalent thereof, wherein the oligonucleotide, or a functional equivalent thereof, comprises a sequence which is complementary to at least part of a dystrophin pre-m RNA exon or at least part of a non-exon region of a dystrophin pre-m RNA said part being a contiguous stretch comprising at least 8 nucleotides. The invention further provides the use of said oligonucleotide for preventing or treating DMD or BMD. |
US11634711B2 |
Methods and compositions for modulating apolipoprotein (a) expression
Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof. |
US11634705B2 |
High-speed in vitro screening method
The purpose of the present invention is to provide a method for identifying antibody CDR3 clusters using high speed in vitro screening a library selected from the group consisting of cDNA library and nucleic acid aptamer library comprising: (i) preparing a positive spherical shaped structure by binding a target molecule to a spherical shaped molecule, wherein the target molecule is immobilized on the positive spherical shaped structure, wherein the positive spherical shaped structure may contain a fluorescent label; (ii) preparing a negative spherical shaped structure, wherein the target molecule is not immobilized on the negative spherical shaped structure, wherein the negative spherical shaped structure may contain a fluorescent label; (iii) forming a positive spherical shaped conjugate or a negative spherical shaped conjugate by binding a target detecting molecule capable of binding to the target molecule to the positive spherical shaped structure or to the negative spherical structure, wherein the target detecting molecule is selected from the library having a size equal to or more than 1010 or equal to or less than 1014, wherein the target detecting molecule may contain a fluorescent label; (iv) separating the positive and the negative spherical shaped conjugates using a fluorescence cell sorter; (v) selecting the separated positive and the separated negative spherical shaped conjugates at least 1 time and then eluting the selected conjugates to obtain an eluted sample; (vi) amplifying a nucleic acid in the eluted sample using PCR to obtain PCR products; (vii) separating the PCR products using the fluorescence cell sorter; and (viii) conducting amplicon sequencing for CDR3 cluster analysis to identify the antibody CDR3 clusters. |
US11634704B2 |
Ligand-guided-selection method for screening antigen-specific ligands
A Ligand-guided-Selection (LIGS) method for identifying highly specific aptamers against a predetermined antigen of a target is provided. LIGS uses a stronger and highly specific bivalent binder (e.g. an antibody) interacting with its cognate antigen to displace specific aptamers from an enriched SELEX pool. Elution of the displaced aptamers provides aptamers that are specific to the predetermined antigen. |
US11634695B2 |
Vectors for expression of biocatalysts
The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents. |
US11634690B2 |
Agent for accelerating growth of pluripotent stem cells
An object of the present invention is to provide a material capable of further accelerating growth of pluripotent stem cells, such as pluripotent stem cells, without impairing pluripotency thereof. In other words, the invention is an agent for accelerating growth of pluripotent stem cells, containing a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, and a solvate thereof as an active ingredient; and is a method for culturing pluripotent stem cells, including culturing pluripotent stem cells in a culture medium that contains a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, and a solvate thereof. |
US11634689B2 |
Method and composition for inducing chondrogenesis or tenogenesis in mesenchymal stem cells
A cell medium for in vitro inducing chondrogenesis or tenogenesis in mesenchymal stem cells (MSCs). The medium is a glucose medium supplemented with at least one growth factor is chosen from the group of fibroblast growth factors (FGF) or the group of transforming growth factors (TGF), and the FGF or TGF is present in a total concentration of between 1 and 15 ng/ml. In both cases, IGF can be added to enhance the induction process. The use of the cell medium, a method for inducing isolated mesenchymal stem cells (MSCs) and a cell composition obtained by the method are also provided. |
US11634686B2 |
Method of producing naive pluripotent stem cells
Provided herein are compositions and methods for generation of naive human pluripotent stem cells. The method comprises incubation of iPSCs under 5% O2 in a medium comprising 5% glucose, an MEK inhibitor, a GSK3β inhibitor, human leukemia inhibitory factor (LIF), human insulin and Torin 1. The method does not need any other inhibitors or transgene expression. The naive human pluripotent cells can be used to generate a large amount of mature human cells from all three germ layers in host non-human animals. |
US11634683B2 |
Non-enzymatic method and milling device
Non-enzymatic method and milling device for preparing therapeutic cells from adipose tissue comprising: continuously feeding the adipose tissue to the milling device (2); mechanically separating the cells or cell aggregates from adipose tissue moving through the milling device (2) by means of a multiplicity of blades (19) of a rotor (10), wherein the blades (19) are arranged in a spaced arrangement with respect to the overall direction of flow and the blades (19) are moving about an axis of rotation (18), wherein the axis of rotation (18) is provided essentially parallel to said overall direction of flow; continuously withdrawing the processed tissue comprising the separated cells from the milling device (2). |
US11634674B2 |
Method and equipment for pressurized injection of air or other gases in a controlled manner into wine making tanks
A method and equipment for the pressurized injection of air or other gases in a controlled manner into wine making tanks or similar for the purpose of efficiently breaking up the cap and extracting polyphenolic and aromatic compounds from the skins to the liquid portion (must) after the crushing of the grapes using the method for pumping over the grape harvest during the maceration thereof. |
US11634672B2 |
Disinfecting solution wipes
This present invention relates to a pre-packaged set of disinfecting solution wipes used to prevent urinary tract and other infections, and reduce to bacterial growth. The wet wipes are stored in packages until needed, and are infused with a novel water and vinegar solution. The wipes can be applied multiple times a day to help eliminate odors, soothe skin, and reduce bacteria growth by neutralizing the pH of the user's skin. The wipes may also be used as a temporary bathing solution for those without immediate access to a shower or bathroom. The containers of the present invention are reusable, and feature a sealed lid to prevent the wet wipes from prematurely drying out. |
US11634669B2 |
Aerosol detergent composition
A nonflammable aerosol composition for washing various types of car/vehicle is of low toxicity, which has little environmental impact in terms of depletion of the ozone layer and so forth, which has a washability as good as or better than conventional products such as has been unattained by aqueous products or high-flash-point products, which permits achievement of appropriate drying characteristics, and which, while preventing erosion of rubbers and resins, causes dirt components to be moistened and washed off and away therefrom by the detergent composition, and which permits accommodation of mechanization by virtue of its being capable of being sprayed thereonto from a roughly constant distance therefrom, said aerosol composition for washing is made to contain (Z)-1-chloro-3,3,3-trifluoropropene and gas propellant which is N2, compressed air, CO2, argon, or a mixture of two or more thereof. |
US11634666B2 |
Methods for spore removal comprising a polysorbate surfactant and cationic antimicrobial mixture
Disclosed herein are methods for removing spores from skin, the method including dispensing an effective amount of a composition into or onto an article, wherein the composition includes water and from about 0.04 wt % to about 4 wt % polymeric cationic antimicrobial, nonionic antimicrobial or combinations thereof; contacting a skin surface with the composition; mechanically acting on the skin surface for at least one (1) second while the skin surface is in the presence of the composition; and removing at least a portion of the composition from the surface of the skin, wherein removing the composition also removes spores from the skin surface. |
US11634659B2 |
Fragrances with rose scent
The present invention primarily concerns the use of compounds of the following formula (I) wherein X represents an oxygen atom, a —CHO, an —OH, or a —CH2OH group, a single bond or a double bond is present at the respective location of one of the dotted lines, at least one double bond is present when X is an OH group, and the 3-isopentyl or 3-isopent-2-enyl residue is connected to the ring in the ortho, meta, or para position to the X group, as perfuming and/or flavouring agents. The invention further relates to fragrance and flavour compositions containing one or more of these compounds, perfumed or flavoured articles comprising one or more of these compounds and corresponding processes for imparting, modifying and/or enhancing certain odour notes. |
US11634658B2 |
Stability of short path evaporation treated oils
The present invention relates to a process for increasing the oxidative stability of short path evaporated oils, by adding to short-path evaporated treated oil at least one other oil. It further relates to a composition comprising short-path evaporated treated palm oil and, at least one other oil. Furthermore, it relates to the food products comprising these oils with improved oxidative stability. |
US11634657B2 |
Method for refined palm oil production with reduced 3-MCPD formation
Methods of refining palm oil in order to produce a refined, bleached and deodorized palm oil with reduced level of 3-monochloropropane-1, 2-diol (3-MCPD) ester are disclosed. The methods may include premixing a palm oil with an acid to chelate metals and form a reaction mixture, and subjecting the reaction mixture to hydrodynamic cavitation mixing for less than 1 second. |
US11634656B2 |
Hydrophilic lubricating coating for medical catheters and its preparation method
The invention discloses a photocured medical catheter hydrophilic lubricating coating and a preparation method thereof. The hydrophilic lubricating coating comprises a primer coating and a lubricating coating. The primer coating is attached to the surface of a device, and the lubricating coating is attached to the primer coating. The primer coating comprises 1-10 parts by weight of one or more polyester acrylates, 50-90 parts by weight of one or more solvents, 0.5-5 parts by weight of one or more photoinitiators, 0.5-2 parts by weight of one or more wetting agents and 0.5-5 parts by weight of one or more reactive (or active) diluents. The lubricating coating comprises 1-10 parts by weight of one or more water soluble macromolecules, 1-5 parts by weight of one or more crosslinking (or crosslinked) macromolecules, 0-1 part by weight of one or more photoinitiators, 0.1-1 part by weight of one or more surfactants and 50-98 parts by weight of one or more solvents. The preparation method of the hydrophilic lubricating coating is simple and easy in operation. Substance residues caused by complicated high-temperature chemical reactions are avoided. The cured coating forms a crosslinking (or crosslinked) structure, has good adhesion on the surface of a medical catheter and has excellent and lasting lubricity in an aqueous medium. The friction coefficient of the surface of the medical catheter is reduced. Harm to human tissues and adhesion of macromolecules in blood are decreased. |
US11634655B2 |
Engine oils with improved viscometric performance
A multi-grade lubricating oil including a (meth)acrylate polymer with at least two distinct molecular weight arms and a blend of heavier and lighter base oils with increased amounts of the heavier base oil to achieve SAE grade performance. The compositions herein achieve SAE certifications as lower CCS viscosities at target kinematic viscosities for multi-grade oils. |
US11634652B2 |
Use of a paraffinic gasoil
Use of a paraffinic gasoil in a diesel fuel composition for reducing the build up of deposits in an Exhaust Gas Recirculation (EGR) system of a compression ignition internal combustion engine. |
US11634651B2 |
System and method for biogasification
Embodiments of the invention improve the performance, safety, and efficiency of the gasification process. Embodiments of the invention improve downdraft gasification by improving upon the systems and methods for fuel preparation and by addressing gasifier bridging and channeling. Unique parts of the system include a unique hearth and grate design, a programmable logic controller and interface for managing the gasification process, an improved filtration system, a unique system for eliminating mist, a unique system for cooling gas, a unique combined flare, an integrated auger system, and a new system and method for sampling gas. |
US11634650B2 |
Method of producing liquid fuel from carbonaceous feedstock through gasification and recycling of downstream products
A feedstock delivery system transfers a carbonaceous material, such as municipal solid waste, into a product gas generation system. The feedstock delivery system includes a splitter for splitting bulk carbonaceous material into a plurality of carbonaceous material streams. Each stream is processed using a weighing system for gauging the quantity of carbonaceous material, a densification system for forming plugs of carbonaceous material, a de-densification system for breaking up the plugs of carbonaceous material, and a gas and carbonaceous material mixing system for forming a carbonaceous material and gas mixture. A pressure of the mixing gas is reduced prior to mixing with the carbonaceous material, and the carbonaceous material to gas weight ratio is monitored. A transport assembly conveys the carbonaceous material and gas mixture to a first reactor where at least the carbonaceous material within the mixture is subject to thermochemical reactions to form the product gas. |
US11634647B2 |
Tower bottoms coke catching device
A coke catching apparatus for use in hydrocarbon cracking to assist in the removal of coke and the prevention of coke build up in high coking hydrocarbon processing units. The apparatus includes a grid device for preventing large pieces of coke from entering the outlet of the process refining equipment while allowing small pieces of coke to pass through and be disposed of. The coke catching apparatus can be easily disassembled to be removed from the refining process equipment and cleaned. |
US11634646B2 |
Oilfield natural gas processing and product utilization
A remote hydrocarbon processing system comprising a gas compressor skid, gas processing skid, electric power generation skid, liquid storage tank, blending skid, and crude oil source, are fluid flow interconnected and located proximate to a producing well. Produced gases are delivered from the well to the gas compressor skid. Compressed natural gas is delivered to the gas processing skid where it is thermally separated to generate a processed gas stream and a processed liquid stream. The processed gas stream is delivered to the electric power generation skid and burned to generate electricity that may be delivered to an electric power transmission line. The processed liquid stream is delivered to the liquid storage tank. Crude oil from the crude oil source and processed liquid stream from the liquid storage tank are delivered to the Blending skid and blended into a lower viscosity, higher API gravity transportable crude oil. |
US11634644B2 |
Fast pyrolysis heat exchanger system and method
A fast pyrolysis heat exchanger system for economically and efficiently converting biomass and other combustible materials into bio-oil. The system employs multiple closed loop tubes situated inside the heat exchanger. As a granular solid heat carrier is deposited at the top of the heat exchanger and caused to move downwardly therethrough, heat is transferred from the tubes to the heat carrier which is then transferred to a reactor where it is placed in contact with the combustible materials. |
US11634640B2 |
Liquid crystal composition and liquid crystal display device having same
A liquid crystal composition includes at least one compound of general formula I, at least one compound of general formula II and at least one compound of general formula III. The liquid crystal composition has a higher optical anisotropy, the relatively large elastic constants K11 and K33 while maintaining a relatively high clearing point, an appropriate dielectric anisotropy and a better low-temperature intersolubility. A liquid crystal display device which includes the liquid crystal composition has advantages of a fast response, a high contrast and a wide temperature range, thereby having a good display effect and a large range of applicability. |
US11634636B2 |
Method for manufacturing resin thin film stripped pieces
A method for producing flakes of a resin thin film including: a step (1) of forming a resin thin film on a substrate film to obtain a multilayer film; a step (2) of pressing the multilayer film by a member having a concavo-convex shape to form cracks in the resin thin film; and a step (3) of stripping the resin thin film from the substrate film to obtain flakes. The step (2) is preferably performed with a pressing pressure of 100 MPa or less. The resin thin film is preferably formed of a cured product of a photocurable liquid crystal composition. The resin thin film is preferably a cholesteric resin layer. |
US11634635B2 |
Polyacrylate polymers for low carbon steel corrosion control
Methods are provided to inhibit corrosion in low hardness water systems. The corrosion inhibiting treatment comprises: calcium salts of low molecular weight polymer polycarboxylic acids. These calcium salts may be added preformed to the water system in need of treatment or formed in-situ in the system. This method of corrosion inhibition is not a source of addition phosphorous or heavy metal to the treated system. |
US11634633B2 |
Composition for etching
The disclosure is related to a composition for etching, a method for manufacturing the composition, and a method for fabricating a semiconductor using the same. The composition may include a first inorganic acid, at least one of silane inorganic acid salts produced by reaction between a second inorganic acid and a silane compound, and a solvent. The second inorganic acid may be at least one selected from the group consisting of a sulfuric acid, a fuming sulfuric acid, a nitric acid, a phosphoric acid, and a combination thereof. |
US11634630B2 |
Phosphor and light source device
A phosphor and a light source device having the phosphor having a high internal quantum yield by enabling a large Ce amount, capable of shifting the fluorescence wavelength of yellow fluorescence to the long wavelength side, having satisfactory heat quenching resistance, and excellent in blue light transmittance. The phosphor includes a Ce:YAG single crystal having a Ce amount of 0.7 parts by mole or more when the total amount of Y and Ce is 100 parts by mole. |
US11634625B2 |
Siloxane surfactant additives for oil and gas applications
A well treatment additive includes a siloxane surfactant, a solvent and an aqueous phase. The solvent is preferably a terpene hydrocarbon. Also disclosed is a method for using the well treatment additive to form and enhance the properties of terpene solvent based additives useful for the treatment of oil and gas wells. Methods of using the novel well treatment additives include using the additives in a variety of well treatment processes including, but not limited to, acidizing operations, hydraulic fracturing operations, well remediation operations and water removal operations. |
US11634624B2 |
Surfactants for enhanced oil recovery
The anionic cocogem surfactant of formula (I) for an oil production process of increased efficiency wherein each R1 and R2 is independently selected from hydrogen or C1-C18 straight or branched alkyl optionally substituted by OH; each R3 is independently selected from hydrogen; C1-C25 straight or branched alkyl or alkenyl optionally comprising inter-chain amido-group; aromatic group optionally substituted by C1-C25, preferably C5-C20, more preferably C5-C15 straight or branched alkyl, preferably selected from phenyl and diphenylether; or C10-C20 straight or branched alkenyl, alkadienyl or alkatrienyl; Z is C1-C18 straight or branched alkylene optionally substituted by one or two C1-C6 alkyl or preferably C3-C6 cycloalkyl, optionally comprising (EO)n and/or (PO)m groups, wherein EO is ethylene-oxide i.e. —CH2CH2O—, and PO is propylene-oxide, i.e. —CH(CH3)CH2O—, wherein n and m is independently an integer of from 0 to 30 and n+m is an integer of from 1 to 30; and/or [NH(R4)]+ quaternary ammonium, wherein R4 is hydrogen, C1-C6 alkyl, preferably methyl or ethyl; R5 is hydrogen or C1-C6 alkyl, preferably methyl or ethyl; An is one or more groups selected from SO3−, Cl− or CO2−; i is an integer of 0 or 1; p is an integer of 2 or 3; j is an integer of 2 or 3. |
US11634623B2 |
Quaternary ammonium salts for corrosion inhibition
The present disclosure provides a bis-quaternary ammonium salt of Formula I wherein A is selected from O, NH, S, C(O), C(NH) or C(S); R1 and R2 are independently selected from C1-3 alkyl or H; R3 is C1-16 alkyl, C13-20 aralkyl or C2-16 allyl; X− is selected from chloro, bromo, iodo, hydroxide, nitrate or sulphate; and n and m are independently 1 to 6. Furthermore, a corrosion inhibition formulation comprising said bis-quaternary ammonium salt is revealed. Also, convenient processes for the preparation of the salt of Formula I and the formulation are provided. |
US11634622B2 |
Compositions and methods for scavenging H2S
A method of treating a fluid, which method includes the steps of: (a) contacting a fluid containing at least one sulfide with a sulfide-reducing amount of a composition comprising an lignocellulosic liquor comprising one or more lignin-derived compounds and one or more hemicellulose sugar monomers and/or oligomers and (b) allowing the lignocellulosic liquor to react with at least a portion of the sulfide in the fluid. |
US11634617B2 |
Adhesive composition, a process of producing the adhesive composition, a bonding method using the adhesive composition, and a structure having the adhesive composition applied thereon
The present invention has for its object to provide an adhesive composition that is based on a naturally occurring material less likely to have adverse influences on the human body and has a tensile shear strength (adhesive strength) of at least 1 MPa with respect to a variety of adherends. The present invention provides an adhesive composition including at least a first pack and a second pack, wherein the first pack contains a tannic acid derivative in which a hydrogen atom in at least some hydroxyl group of tannic acid is substituted by a chain hydrocarbon group having at least one hydroxyl group, and the second pack contains a hydrocarbon having at least two cyanate groups or a derivative of the hydrocarbon. |
US11634616B1 |
Methods of assembling apparel products having boronate adhesives
Embodiments provide methods of assembling an apparel product. The methods include applying a composition to a portion of a major component of the apparel product or a portion of a minor component of the apparel product. The portion of the minor component is coupled with the portion of the major component via the composition. The major component forms a base portion of the apparel product and is configured to be supported and worn at least partially over a portion of a wearer. The minor component forms a secondary portion configured to be coupled to the major component with an adhesive. The composition is converted to the adhesive to form the apparel product. The adhesive includes a material having a boronate ester bond. |
US11634614B2 |
Method for manufacturing semiconductor device, heat-curable resin composition, and dicing-die attach film
A method for manufacturing a semiconductor device according to an aspect of the present disclosure includes a step of preparing a dicing/die-bonding integrated film including an adhesive layer formed of a heat-curable resin composition having a melt viscosity of 3100 Pa·s or higher at 120° C., a tacky adhesive layer, and a base material film; a step of sticking a surface on the adhesive layer side of the dicing/die-bonding integrated film and a semiconductor wafer together; a step of dicing the semiconductor wafer; a step of expanding the base material film and thereby obtaining adhesive-attached semiconductor elements; a step of picking up the adhesive-attached semiconductor element from the tacky adhesive layer; a step of laminating this semiconductor element to another semiconductor element, with the adhesive interposed therebetween; and a step of heat-curing the adhesive. |
US11634611B2 |
Sheet and composite sheet
A problem is to provide a sheet having a pre-sintering layer, the thickness of which following sintering is such as to be capable of relieving stresses. Solution means relate to a sheet comprising a pre-sintering layer. Viscosity at 90° C. of the pre-sintering layer is not less than 0.27 MPa·s. Thickness of the pre-sintering layer is 30 μm to 200 μm. |
US11634609B2 |
Polymers, coating compositions containing such polymers, and anti-fingerprint coatings formed therefrom
A substrate at least partially coated with an anti-fingerprint coating is prepared from a coating composition that includes: (a) an organic solvent; and (b) an alkoxysilane functional polymer having at least one ester linkage, at least one urethane linkage, and at least one alkoxysilane functional group. Further, the polymer is prepared from components including: (i) an active hydrogen functional compound having a hydroxyl group, amino group, thiol group, or a combination thereof; (ii) an intramolecular cyclic ester; and (iii) an isocyanate functional compound. The active hydrogen functional compound (i), the isocyanate functional compound (iii), or both (i) and (iii) have one or more alkoxysilane functional groups. Alkoxysilane functional polymers and coating compositions containing the same are also included. |
US11634608B2 |
Compound having isocyanuric skeleton and composition in which said compound is included
A compound represented by the following formula (1): wherein R1 is a monovalent organic group containing a polyether chain; X1 and X2 are each individually a monovalent group; and the polyether chain is a chain represented by the following formula: —(OC6F12)m11—(OC5F10)m12—(OC4F8)m13—(OC3X106)m14—(OC2F4)m15—(OCF2)m16—, wherein m11, m12, m13, m14, m15, and m16 are each individually an integer of 0 or 1 or greater; X10s are each individually H, F, or Cl; the repeating units are present in any order; and the sum of m11 to m16 is an integer of 10 or greater, R1 being other than those containing a urethane bond. |
US11634604B2 |
Polysaccharide compositions and particulate materials coated therewith
Loose particulate materials can be problematic in various aspects. For example, loose particulate materials may generate dust or be difficult to consolidate together. Fines in loose particulate materials may also be an issue. Coated particulates may alleviate some of the foregoing issues. Suitable coated particulates may comprise a particulate material comprising sand or a ceramic, and a polysaccharide composition coated upon the particulate material, the polysaccharide composition comprising a functionalized polysaccharide. Other particulate materials such as wood chips and animal litter particulates may be coated with functionalized polysaccharides to achieve similar advantages. |
US11634601B2 |
Aqueous ink composition for ballpoint pen
To provide an aqueous ink composition for ballpoint pen having excellent ink discharge properties at the initial writing (initial touch) even after exposure of the pen tip for a long period of time. The aqueous ink composition for ballpoint pen contains at least 0.1 to 5% by mass of a graft compound of an allyl alcohol-maleic anhydride-styrene copolymer composed of: (a) a polyoxyalkylene alkyl ether unit represented by Formula (I), (b) a maleic anhydride unit, and (c) a styrene unit, the allyl alcohol-maleic anhydride-styrene copolymer having the composition ratio (a):(b):(c) of 25 to 75:25 to 75:0 to 50% by mol and having a mass average molecular weight from 1000 to 50000, and polyoxyalkylene monoalkyl alcohol; 5 to 40% by mass of resin particles; and water; wherein in Formula (I), R represents an alkyl group having 1 to 5 carbons, and m is a positive number of 5 to 50. |
US11634594B2 |
Antimicrobial agent for coatings and finishes
A microbe-resistant coating, coating intermediate, finish, finish intermediate, or colorant that includes an antimicrobial agent. The antimicrobial agent is an inorganic bismuth-containing compound, and may be used in conjunction with other bismuth-containing compounds or other biocidal agents or methods. The bismuth-containing compound may also be used to impart micro-resistance to a coating, coating intermediate, finish, finish intermediate, colorant, processing equipment or vessels. |
US11634589B2 |
Coating composition and optical member
There are provided a coating composition being possible to form a cured film which has excellent transparency and weather resistance, and especially hardness. A coating composition obtained by which a silicon-containing substance as a component (M) and a silica colloidal particle having a primary particle diameter of 2 to 80 nm as a component (S) are mixed, and then the component (M) is hydrolyzed, and the resulting aqueous solution is subsequently mixed with a colloidal particle (C) wherein a component (F) is a modified metal oxide colloidal particle (C) having a primary particle diameter of 2 to 100 nm, which includes a metal oxide colloidal particle (A) having a primary particle diameter of 2 to 60 nm as a core, whose surface is coated with a coating (B) formed of an acidic oxide colloidal particle. |
US11634588B2 |
Low odor water-based coating composition
A low odor aqueous coating composition is described. The composition is a waterbased latex coating composition that includes a binder component with at least one copolymer and a neutralizing component. The composition dries in less than about 10 minutes at a temperature between about 5 to 35° C. and a relative humidity between about 30 and 95% with a pH of 9.5 or less. The coating composition can be used for applications such as road marking and coating exterior surfaces, where use of a low-odor coating is desired. |
US11634582B2 |
Curable white silicone formulation, a reflective material for optical semiconductor module and optical semiconductor device
A curable white silicone composition that is capable of forming a cured product having a high optical reflectance as well as exceptional light resistance is provided.The curable white silicone composition includes (A) an organopolysiloxane having at least 2 alkenyl groups per molecule, (B) a cerium-containing organopolysiloxane, (C) a white pigment, and (D) a curing catalyst. |
US11634581B2 |
Thermally conductive resin composition and thermally conductive sheet using the same
A thermally conductive resin composition capable of maintaining high thermal conductivity and a thermally conductive sheet using the same. A thermally conductive resin composition contains: an addition reaction type silicone resin; a hindered phenol-based antioxidant; a thiol-based antioxidant; a dispersant having a hydrophilic functional group and a silicone chain; and a thermally conductive filler, wherein the thermally conductive resin composition contains 65 to 90% by volume of the thermally conductive filler. |
US11634580B2 |
Curable white silicone formulation, a reflective material for optical semiconductor module, and optical semiconductor device
A white curable silicone composition provides excellent elongation characteristics while providing sufficiently great hardness, which as a result can provide a cured product having excellent toughness.The composition comprises: (A) alkenyl group-containing resinous organopolysiloxane which is represented by an average composition formula: (R13SiO1/2)a(R12SiO2/2)b(R1SiO3/2)c(SiO4/2)d(XO1/2)e, where, in the formula, R1 are each independently a monovalent hydrocarbon group, while at least two R1 are alkenyl groups, X is a hydrogen atom or an alkyl group, 0≤a≤0.7, 0≤b≤0.2, 0≤c≤0.3, 0≤d≤0.8, and 0≤e≤0.2, a+b+c+d=1.0, and c+d>0 are satisfied; (B) linear alkenyl group-containing organopolysiloxane which is represented by R2R32SiO(R32SiO)nSiOR2R32, where, in the formula, R2 is an alkenyl group, R3 are each independently a monovalent hydrocarbon group other than an alkenyl group, and n is an integer of 50 or greater; (C) organohydrogenpolysiloxane having at least two hydrogen atom-bonded silicon atoms in one molecule; (D) a catalyst for curing reaction; and (E) a white pigment, wherein the component (A) is included in an amount of 20 mass % or more based on the total mass of the organopolysiloxane components, and the alkenyl group content in the components (A) to (C) is 1.7 mass % or less. |
US11634575B2 |
Thermoplastic resin composition, method of preparing the same, and molded article including the same
The present invention relates to a thermoplastic resin composition, a method of preparing the same, and a molded article including the same. More specifically, the present invention relates to a thermoplastic resin composition including 100 parts by weight of a base resin including a vinyl cyanide compound-conjugated diene compound-aromatic vinyl compound graft copolymer and an α-methyl styrene compound-vinyl cyanide compound copolymer and 0.4 to 3 parts by weight of an alkoxylated polyethyleneimine, a method of preparing the thermoplastic resin composition, and a molded article including the thermoplastic resin composition. The thermoplastic resin composition according to the present invention has improved chemical resistance to solvents such as thinner without degradation in fluidity and mechanical properties, and thus has excellent paintability. |
US11634574B2 |
Rubber-containing graft polymer, resin composition containing rubber-containing graft polymer, and shaped article of same
Provided is a rubber-containing graft polymer which is excellent in mechanical strength such as weld strength or impact strength, required as a rubber-containing graft polymer. A rubber-containing graft polymer (A) of the present invention is a rubber-containing graft polymer having a graft chain, in which when the rubber-containing graft polymer is mixed with an organic solvent and separated into an organic solvent insoluble component and an organic solvent soluble component, a caprolactone unit is contained in a graft chain contained in the organic solvent insoluble component. |
US11634573B2 |
UV shielding bio-derived furanic polymers
UV shielding bio-derived furanic polymers (BFP) and UV-shielding composite films containing BFP having another polymer of natural or synthetic origin at varying concentration with high thermal stability, mechanical stability and elasticity are prepared through solvent evaporation casting. A process for preparing BFP having varying physicochemical properties can be carried out via dehydration of various biomass saccharides in different solvents employing various catalysts. The resulting brown-colored films show excellent UV shielding in the region 200 nm to 400 nm and exhibit high optical transparency. The UV shielding efficiency of the film increases with an increase in its treatment temperature. The films are stable and durable in terms of mechanical stability and elasticity even after exposing to harsh conditions without affecting their UV-shielding efficiency. |
US11634571B2 |
Soft and transparent propylene compolymers
The present invention is directed to a polypropylene composition (C) comprising a heterophasic propylene copolymer (RAHECO) and a plastomer (PL) as well as a process for the preparation of said polypropylene composition and a film obtained from said polypropylene composition (C). |
US11634568B2 |
Air curable ethylene/alpha-olefin/diene interpolymer composition
A composition is composed of (A) an ethylene/alpha-olefin/diene TEMPO compound having the Structure (I) and (D) a peroxide. The molar ratio of isocyanate groups of Component (B) to the functional groups of Component (C) is from 0.80 to 1.10. A composition is composed of (A) an ethylene/alpha-olefin/diene interpolymer; a second composition comprising a reaction mixture comprising (B) an isocyanate comprising at least two isocyanate groups and (C) a TEMPO compound having the Structure (I) and (D) a peroxide, wherein the molar ratio of isocyanate groups of Component (B) to the functional groups of Component (C) is from 0.80 to 1.10. In Structure I, R1, R2, R3 and R4 are each independently selected from H and C1-C6 alkyl groups and X is a functional group selected from OH and NH2. |
US11634567B2 |
Dual component LLDPE copolymers with improved impact and tear resistance, and methods of their preparation
Disclosed are ethylene polymer compositions containing a homogeneously-branched first ethylene polymer component and 15-35 wt. % of a homogeneously-branched second ethylene polymer component of higher density than the first ethylene polymer component. The ethylene polymer composition can be characterized by a density from 0.912 to 0.925 g/cm3, a ratio of Mw/Mn from 2 to 5, a melt index less than 2 g/10 min, and a CY-a parameter at 190° C. from 0.35 to 0.7. These polymer compositions have the excellent dart impact strength and optical properties of a metallocene-catalyzed LLDPE, but with improved machine direction tear resistance, and can be used in blown film and other end-use applications. Further, methods for improving film Elmendorf tear strength also are described. |
US11634566B2 |
Rubber composition, processing method thereof, and rubber product using the same
The present invention discloses a rubber composition, production method thereof and a rubber product using the same. The rubber composition includes a rubber matrix and essential components. Based on 100 parts by weight of the rubber matrix, the rubber matrix includes a branched polyethylene with a content represented as A, in which 0 |
US11634565B2 |
Caps or closures made from a resin composition comprising polyethylene
Described herein are caps or closures made from a resin composition having at least one polyethylene having a density of at least 0.940 g/cm3 when measured following the ISO 1183-2 method at 23° C.; erucamide; and at least 700 ppm based on the total weight of the resin composition of at least one ultraviolet absorber selected from the hydroxyphenylbenzotriazole class. A process for the production of such caps or closures is also described herein. |
US11634564B2 |
High heat and oil resistant conveyor belt
Conveyor belts having a reinforcement layer, a carry cover layer above the reinforcement layer, and a pulley cover layer disposed beneath the reinforcement layer, where the carry cover layer includes least one hydrogenated nitrile butadiene rubber (HNBR) material. The HNBR material(s) may have a percentage of hydrogenation of from about 90% to about 96%, from about 92% to about 95%, or even about 94%. The carry cover layer may be from about 4 mm to about 6 mm thick, or even from about 4 mm to about 5 mm thick. In some cases, the reinforcement layer includes a rubber matrix, which may be formed of a nitrile rubber (NBR), or mixture of nitrile NBR and natural rubber blended in a NBR:NR weight ratio of from 3:1 to 9:1. In some aspects, the reinforcement layer includes a plurality of reinforcement plies embedded in the rubber matrix. |
US11634562B2 |
Tire composition and method for making thereof
The disclosure relates to tire tread compositions and methods for making. The compositions include a rubber, a rosin ester resin and at least one filler. The rosin ester resin is characterized as having a PAN number of less than 25, an acid number less than 20, a hydroxyl number of less than 30, a combined acid number and hydroxyl value of less than 50. The tire tread composition has a wet grip resistance to rolling resistance indicator ratio ((tan δ at 0° C.)/tan δ at 60° C.) higher than a tire tread composition containing a comparable amount of a rosin ester having a combined acid number and hydroxyl value of more than 50. |
US11634559B2 |
Method for producing resin composition and method for producing molded article
A method for producing a resin composition of the present invention is a method for producing a resin composition, the method including a step of obtaining a resin composition by heating and melt-kneading a mixture containing a particulate nucleating agent in which D50 is equal to or more than 0.1 μm and equal to or less than 300 μm and a thermoplastic resin using a twin screw extruder (100) including, inside a cylinder (10), a screw (50) having kneading discs (60), in which the step of obtaining a resin composition includes an extrusion step of extruding the mixture supplied into the twin screw extruder (100) in an ejection direction under kneading conditions in which X and Y satisfy 4.0≤X in a range of 6.0×103≤Y≤7.0×104 when a volume-based ejection amount is denoted by X (10−6·kg·h−1·mm−3), and a strain rate is denoted by Y (min−1). |
US11634552B2 |
Organic amine salt foamer
Disclosed is an organic amine salt foaming agent, that is, a composite polyurethane foaming agent, comprising: 1) hexafluorobutene; and 2) an alkanolamine salt mixture (MAA), the alkanolamine salt mixture (MAA) contains an organic amine salt compound having the following general formula (I): An−[Bm+]p (I); wherein An− is one or two or three selected from the following anions: (b) carbonate: CO32−; (c) formate: HCOO−; (d) bicarbonate: HO—COO−. A polyurethane foaming method using carbon dioxide and an organic amine in combination is also disclosed, in which carbon dioxide is added to a polyurethane composition for foaming. A method for preparing an alkanolamine carbonate salt with low water content from ammonium carbonate and an epoxide is additionally disclosed, in which a liquid alkanolamine salt mixture is used as a dispersion medium or as a solvent for reaction raw material. |
US11634547B2 |
Water-soluble film, production method thereof, and chemical agent package
A water-soluble film is provided, which is less susceptible to curling even after long-term storage. The water-soluble film includes a polyvinyl alcohol resin (A) , and has a first surface, which has a crystal Unity index Xa, and a second surface, which is opposite to the first surface and has a crystallinity index Xb, where: Xa≥Xb; Xa−Xb is from 0.015 to 0.10; and the crystallinity indexes Xa and Xb are measured through an infrared spectroscopic analysis by an attenuated total reflection method and represented by: ABS1141/ABS1093, wherein ABS1141 and ABS1093 are absorbances at wavenumbers of 1141 cm−1 and 1093 cm−1, respectively. |
US11634538B2 |
Polycarbonate resin and method for producing same
The purpose of the present invention is to provide: a polycarbonate resin which has a narrow molecular weight distribution and in which the formation of low molecular weight oligomers is suppressed; and a method for producing the polycarbonate resin.According to the present invention, provided are a polycarbonate resin containing a structural unit represented by general formula (1), wherein the molecular weight distribution value (Mw/Mn) is 6.0 or less, and the content of oligomers having a molecular weight of less than 1,000 is suppressed to 0.50 mass % or less; and a method for producing the polycarbonate. (In general formula (1), R1-26 represent hydrogen, fluorine, chlorine, bromine, iodine, a C1-9 alkyl group, a C6-12 aryl group, a C1-5 alkoxy group, a C2-5 alkenyl group, or a C7-17 aralkyl group). |
US11634536B2 |
Tufted carpet including polyethyleneterephthalate bulked continuous filament
A polyethylene terephthalate bulked continuous filament is manufactured by steps of melt-spinning, multi-step stretching a polyethylene terephthalate chip and a master batch chip for coloring, passing through a texturing nozzle, cooling, and winding and has an elastic modulus of 1.00E+07 to 5.00E+09 Pa at a temperature range of 10° C. to 200° C., the filament being manufactured by steps of melt-spinning a polyethylene terephthalate chip and a master batch chip for coloring, multi-step stretching, passing through a texturing nozzle, cooling, and winding. |
US11634535B2 |
Polymer compound and method of synthesizing the same
Provided is a polymer compound having a furan ring having a degree of polymerization of 185 or more and 600 or less. This polymer compound has excellent mechanical strength (flexural strength). |
US11634533B2 |
Resin composition
The present application relates to a composition, a battery module and a battery pack. According to one example of the present application, it is possible to provide a battery module and a battery pack which have improved heat dissipation properties, adhesive force, adhesion reliability and processability as well as excellent power to volume. |
US11634530B2 |
Method for manufacturing artificial leather
An object to be achieved by the present invention is to provide a method for producing an artificial leather on a practically usable level without using an organic solvent and without requiring a crosslinking step for a crosslinking agent. The present invention provides a method for producing an artificial leather having a cured product layer of a moisture-curing urethane hot-melt resin composition, wherein the moisture-curing urethane hot-melt resin composition contains a urethane prepolymer having an isocyanate group and does not contain a crosslinking agent having a hydroxyl group and/or an amino group, the method including applying the moisture-curing urethane hot-melt resin composition to a substrate at a coating weight of 0.03 to 0.5 kg/m2 so as to form a cured product layer of the moisture-curing urethane hot-melt resin composition. |
US11634529B2 |
Multilayer structure
This disclosure relates to a multilayer structure containing: a substrate; a coupling layer deposited on the substrate; and a dielectric layer deposited on the coupling layer, wherein shear strength is increased by a factor of at least about 2 in the presence of the coupling layer compared to a multilayer in the absence of the coupling layer. |
US11634528B2 |
Latent imaging for volume Bragg gratings
Initiator/mediator chemistry for latent imaging polymers for volume Bragg gratings is provided. Light mediated chemistry including the use of nitroxides allows a first step imaging to occur, where a light induced pattern is recorded in the material, without the grating being apparent. A second bleaching/developing step completes the curing process and reveals the grating. |
US11634521B2 |
Particle size control of metallocene catalyst systems in loop slurry polymerization reactors
Catalyst compositions containing a metallocene compound, a solid activator, and a co-catalyst, in which the solid activator or the supported metallocene catalyst has a d50 average particle size of 15 to 50 μm and a particle size distribution of 0.5 to 1.5, can be contacted with an olefin in a loop slurry reactor to produce an olefin polymer. A representative ethylene-based polymer produced using the catalyst composition has excellent dart impact strength and low gels, and can be characterized by a HLMI from 4 to 10 g/10 min, a density from 0.944 to 0.955 g/cm3, a higher molecular weight component with a Mn from 280,000 to 440,000 g/mol, and a lower molecular weight component with a Mw from 30,000 to 45,000 g/mol and a ratio of Mz/Mw ranging from 2.3 to 3.4. |
US11634519B2 |
Method for functionalising a stereo-regular polydiene
Disclosed is a functionalizing method for the end functionalisation of trans-1,4 stereo-regular polydiene chains obtained by the coordination catalytic polymerisation of at least one conjugated diene monomer. It also relates to a polydiene having a trans-1,4 chain formation rate of at least 85%, preferably at least 90%, and an end functionalisation rate higher than 70%, preferably higher than 80%, and more preferably higher than 90%. |
US11634517B2 |
Pyrrole-based polymers for metal extraction, analysis, and removal
Materials and methods for extracting metals from solutions, involving a polymer of Formula A are described: where each X is independently either S or O, and n is an integer greater than 1. |
US11634514B2 |
Method for manufacturing fluoropolymer, surfactant for polymerization, use for surfactant, and composition
A method for producing a fluoropolymer which includes polymerizing a fluoromonomer in an aqueous medium in the presence of a surfactant to provide a fluoropolymer, the surfactant being represented by the general formula (1): CR1R2R4—CR3R5—X-A, wherein R1 to R5 are each H or a monovalent substituent, with the proviso that at least one of R1 and R3 represents a group represented by the general formula: —Y—R6 and at least one of R2 and R5 represents a group represented by the general formula: —X-A or a group represented by the general formula: —Y—R6; and A is the same or different at each occurrence and is —COOM, —SO3M, or —OSO3M. Also disclosed is a surfactant for polymerization represented by the general formula (1), a method for producing a fluoropolymer using the surfactant and a composition including a fluoropolymer and the surfactant. |
US11634513B2 |
Process for preparing catalysts and catalyst compositions
Disclosed are support-activators and catalyst compositions comprising the support-activators for polymerizing olefins in which the support-activator includes clay heteroadduct, prepare from a colloidal phyllosilicate such as a colloidal smectite clay, which is chemically-modified with a heterocoagulation agent. By limiting the amount of heterocoagulation reagent relative to the colloidal smectite clay as described herein, the smectite heteroadduct support-activator is a porous and amorphous solid which can be readily isolated from the resulting slurry by a conventional filtration process, and which can activate metallocenes and related catalysts toward olefin polymerization. Related compositions and processes are disclosed. |
US11634512B2 |
Zwitterionically modified polymers and hydrogels
The present invention is directed to a polymer of Formula (IV): wherein A, X, Q, Y, Z, m1; m2, m3, k1; and k2 are as described herein and wherein the monomer units of the polymer are the same or different. The present invention also relates to a monomer of Formula (III), wherein R″, X1, Y1, Z1, m4, m5, and m6 are as described herein, and a polymeric network comprising two or more monomers of Formula (III). The present invention also relates to a hydrogel comprising any of the polymers and monomers described herein, a capsule comprising the hydrogel, and a method of delivering a therapeutic agent to a subject using the capsule. |
US11634510B2 |
Water-soluble cellulose ether and method for producing the same
There are provided a method for efficiently producing a water-soluble cellulose ether without using a special apparatus, and a novel water-soluble cellulose ether. More specifically, there are provided a method for producing a water-soluble cellulose ether including a first pulverization step of pulverizing a starting water-soluble cellulose ether to obtain a first pulverization product, and a first sieving step of sieving the first pulverization product by using a first sieve whose mesh surface is coated with an inorganic metal compound to obtain a first-sieve-passed water-soluble cellulose ether fraction; and a novel water-soluble cellulose ether. |
US11634509B2 |
Fibrous cellulose, method for manufacturing same, and resin composition
A fibrous cellulose having an excellent resin reinforcing effect, a method for manufacturing the fibrous cellulose, and a resin composition having high strength. The fibrous cellulose is microfiber cellulose having an average fiber diameter of 1 μm or more, and is hydrophobically modified. The method for manufacturing fibrous cellulose includes defibrating raw material fiber to obtain microfiber cellulose with an average fiber diameter of 1 μm or more, and hydrophobically modifying the microfiber cellulose. Further, the resin composition contains the fibrous cellulose and resin. |
US11634508B2 |
Peptide conjugates of cytotoxins as therapeutics
The present invention relates to peptide conjugates of cytotoxins such as topoisomerase I inhibitors which are useful for the treatment of diseases such as cancer. |
US11634507B2 |
Dendritic gold nanoparticles and methods of synthesis
A method of producing dendritic gold nanoparticles by combining a gold precursor solution, a reducing agent, and a bifunctional peptide having an amine-rich amino acid sequence into a buffered aqueous solution in a single container, and agitating the mixture causing the formation of the dendritic gold nanoparticles having a surface with a positive charge and a second end portion of the bifunctional peptide exposed on the surface of the dendritic gold nanoparticles. The dendritic gold nanoparticles may be used to deliver therapeutic, diagnostic, and/or immunogenic amino acid sequences as portions of the bifunctional peptide. |
US11634502B2 |
Heterodimeric bispecific antibodies
Provided herein are heterodimeric bispecific antibodies that can mediate cytolysis of a target cell by an immune effector cell, nucleic acids encoding such antibodies, methods of making such antibodies, and methods of using such antibodies. These antibodies comprise two different polypeptide chains, each comprising two immunoglobulin variable regions and, optionally, a half life-extending moiety. |
US11634501B2 |
Immunomodulatory antibodies and methods of use thereof
Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer. |
US11634498B2 |
Chimeric antigen receptors and uses thereof
Aspects of the disclosure relate to chimeric antigen receptors (CARs) comprising an antigen binding domain (e.g., anti-TSHR), transmembrane domain (e.g., CD28), and a cytoplasmic domain (e.g., CD27, CD-137, etc.) and a safety mechanism comprising an inducible apoptosis trigger. In some aspects, the disclosure relates to use of the CARs in T cells, compositions, kits and methods for the treatment of thyroid cancers. |
US11634497B2 |
Anti-CCR7 antibody drug conjugates
This application discloses anti-CCR7 antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents. |
US11634494B2 |
Anti HLA-G specific antibodies
The present invention relates to antibodies, or antigen-binding fragments thereof, directed against human leukocyte antigen-G (HLA-G) protein and raised against an immunogenic peptide derived from the α3 domain of HLA-G protein. The invention further relates to the immunogenic peptide, and methods for producing said anti-HLA-G specific antibodies. |
US11634492B2 |
Dimers and use thereof
The present disclosure provides a dimer formed by two polypeptide chains, with each of the two polypeptide chains comprising an antibody Fc subunit, wherein the dimer comprises two or more immunoglobulin single variable domains (ISVDs), at least one of the ISVDs is specific for PD-L1, and at least one of the ISVDs is specific for CTLA4. |
US11634489B2 |
Anti-TREM2 antibodies and methods of use thereof
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 or human TREM2, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof. |
US11634484B2 |
Use of anti-family with sequence similarity 19, member A5 antibodies for the treatment of neuropathic pain
The present disclosure provides a method for the treatment of a neuropathic pain including a central neuropathic pain or a peripheral neuropathic pain in a subject comprising the administration of antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. The present disclosure also provides methods for treating a neuropathic pain including a symptom of neuropathic pain, and/or an underlining cause of a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5. In a specific aspect, the method comprises administering antibodies specifically bind to human FAM19A5, e.g., binds to soluble human FAM19A5 with a KD of 10 nM or less, or binds to membrane bound human FAM19A5 with a KD of 10 nM or less, or both, as measured by a method known in the art, e.g., ELISA. |
US11634478B2 |
Human immunodeficiency virus neutralizing antibodies and methods of use thereof
The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of HIV infection. |
US11634475B2 |
Therapeutic variant alpha-2-macroglobulin compositions
A2M polypeptide compositions containing a non-natural bait region are disclosed. Methods of producing wild-type and variant A2M polypeptides and polynucleotides containing a non-natural bait region are also disclosed. The bait regions of the variant A2M polypeptides demonstrate enhanced protease inhibitory characteristics compared to wild-type A2M. Variant A2M polypeptides that demonstrate longer half-lives upon administration to an organism compared to wild-type A2M are disclosed. The A2M compositions are useful in treating a number of diseases and conditions including inflammation, chronic wounds, and diseases with a pathology associated with proteases. |
US11634474B2 |
Human serum albumin mutant
Disclosed are a human serum albumin mutant that can be linked to a physiologically active protein to increase the stability of the protein in the blood, as well as a resulting protein produced by linking with the mutant. The protein produced by linking with the mutant consists of a human serum albumin mutant comprising the amino acid sequence set forth as SEQ ID NO:3 or an amino acid sequence that, in comparison with it, lacks not more than 10 amino acid residues and/or has not more than 10 amino acid residues replaced, with the proviso that the asparagine residue occurring at position 318 and the threonine at position 320 from the N-terminus of the amino acid sequence set forth as SEQ ID NO:3 are preserved and linked by peptide bonds via a single amino acid residue (X) except proline placed between those two amino acid residues, and a physiologically active protein linked to the mutant. |
US11634473B2 |
Method and device for fast dissolution of solid protein composition
Provided are methods and devices for dissolving solid protein compositions, such as solid compositions comprising fibrinogen, in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub-atmospheric. Aqueous solvent is introduced into the container while maintain the sub-atmospheric pressure, and subsequent to addition of the solvent, the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method. |
US11634470B2 |
Integrin binding peptides and uses thereof
The disclosure relates to integrin binding peptides, pharmaceutical compositions comprising the peptides and to uses thereof as therapeutic, diagnostic, imaging and targeting agents. |
US11634469B2 |
Vesicular stomatitis viruses
This document provides methods and materials related to vesicular stomatitis viruses. For example, vesicular stomatitis viruses, nucleic acid molecules encoding VSV polypeptides, methods for making vesicular stomatitis viruses, and methods for using vesicular stomatitis viruses to treat cancer are provided. |
US11634466B2 |
Musclin peptides and methods of use thereof
In certain embodiments, the present invention provides a musclin peptide and methods of increasing muscle growth, performance, resistance to injury and/or preventing or reducing muscle atrophy and improving overall skeletal muscle, metabolic and cardiac health in an animal in need thereof by administering a musclin peptide. |
US11634458B2 |
Peptides and compositions for use in cosmetics and medicine
The present invention relates to a family of peptides which are able to interfere in the formation of complex Munc18-Syntaxin-1 and, hence, are useful in the prevention and/or treatment of neuronal exocytosis and/or muscle contractility disorders; and to prevent, reduce and/or eliminate skin aging and/or expression signs. |
US11634457B2 |
Methods of reducing level of one or more impurities in a sample during protein purification
The present invention provides novel and improved protein purification processes which incorporate certain types of carbonaceous materials and result in effective and selective removal of certain undesirable impurities without adversely affecting the yield of the desired protein product. |
US11634456B2 |
Method for the purification of collagen
A process for the extraction of collagen from collagen-containing matter, wherein the process comprises; incubating the collagen-containing matter in an acidic solution to form an incubant, then diafiltrating the incubant to substantially purify solubilised collagen within the incubant, thereby forming a retentate, then separating the soluble and insoluble matter of the retentate to remove the remaining insoluble matter, wherein the soluble matter is a substantially pure collagen solution. |
US11634454B2 |
Sterol derivatives and preparation method and uses thereof
The present invention pertains to pharmaceutical chemical field, and relates to a sterol derivative as well as preparation method and uses thereof. Specifically, the present invention relates to a compound of Formula I, or a pharmaceutically acceptable salt, ester or ether thereof, wherein, R1 is selected from the group consisting of —OH, ═O(carbonyl), H, and C1-C3 alkyl; R2 is selected from the group consisting of —OH, H, and C1-C3 alkyl; R3 is selected from the group consisting of —OH, ═O, H, and C1-C3 alkyl; R4 is selected from the group consisting of —OH, H, and C1-C3 alkyl; and none, one, two, three or four of R1, R2, R3, and R4 are —OH. The compound of the present invention can inhibit HMG-CoA reductase, tumor cells and lipase effectively, and is a potential drug for reducing blood-fat, antitumors, or for losing weight. |
US11634452B2 |
Compounds for treating neurodegenerative disorders
The invention relates to compounds of formula (I), their method of synthesis as well as their use to treat neurodegenerative disorders. |
US11634449B2 |
Macrolides and methods of their preparation and use
Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided. |
US11634446B2 |
Two-dimensional stimuli-responsive covalent organic frameworks with high intrinsic conductivity
In an embodiment, the present disclosure pertains to a method of sensing an analyte in a sample by: (1) exposing the sample to an electrode that includes a covalent-organic framework with a plurality of metal-coordinated aromatic units that are linked to one another by aromatic linkers; (2) detecting a change in a property of the electrode; and (3) correlating the change in the property to the presence or absence of the analyte. In an additional embodiment, the present disclosure pertains to said covalent-organic frameworks. Additional embodiments of the present disclosure pertain to methods of making the covalent-organic frameworks. |
US11634441B2 |
Group 5 metal compound for thin film deposition and method of forming group 5 metal-containing thin film using same
A group 5 metal compound according to an embodiment of the present disclosure is represented by any one of the following |
US11634438B2 |
Heterocyclic compound and organic light-emitting device including the same
An organic light-emitting device and a heterocyclic compound, the device including a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode and including an emission layer, wherein the organic layer includes a heterocyclic compound represented by Formula 1: |
US11634434B2 |
Bifunctional alpha-synuclein binding agents and uses thereof
Bifunctional molecules having first and second alpha-synuclein binding agents coupled by a linker are disclosed. The bifunctional molecules have potential utility in the diagnosis, treatment and/or prophylaxis of disorders in which alpha-synuclein is implicated, including Parkinson's disease. Methods of making and using the bifunctional molecules are disclosed. |
US11634432B2 |
mTORC1 modulators and uses thereof
The disclosure provides compounds and salts that show high selectivity and inhibitory activity for mTORC1 and uses thereof for the treatment of disease, such as Formula I: or a pharmaceutically acceptable salt thereof. |
US11634429B2 |
Organic electro-optic chromophores
Chromophores with large hyperpolarizabilities, films with electro-optic activity comprising the chromophores, and electro-optic devices comprising the chromophores are disclosed. |
US11634428B2 |
Deuterated angiotensin-converting enzyme-2 (ACE-2) inhibitors
The present invention is concerned with novel deuterated Angiotensin-Converting Enzyme-2 (ACE-2) inhibitors of general structural formula I, their optically active enantiomers and diastereoisomers, and pharmaceutical salts and compositions thereof, as well as combination therapies which include compounds of the present invention, These compounds have high potency and selectivity for Angiotensin-Converting Enzyme-2 (ACE-2) inhibition, and are useful in the treatment of infectious respiratory diseases including the pandemic disease Covid-19, Severe Acute Respiratory Syndrome (SARS-CoV-2), Severe Acute Respiratory Syndrome (SARS-CoV), and other diseases caused by coronaviruses. |
US11634425B2 |
Pharmaceutical compounds
Benzodiazepine derivatives of formula (I): (I) wherein: each of R1 and R2 is independently H or halo; either (i) T is N, Z is C, -a- and -c- are bonds, and -b- and -d- are absent; or (ii) T is C, Z is N, -b- and -d- are bonds, and -a- and -c- are absent; each of R3 and R4 is independently halo, —OR6, —NR6R7—COR8, —C(O)OR8, —CON(R8)2 or —R6; R5 is H or halo; each of R6 and R7 is independently H or a group selected from C1-C6 alkyl, C3-C10 cycloalkyl, C6-C10 aryl, 4- to 10-membered heterocyclyl and 4- to 10-membered heteroaryl, the group being unsubstituted or substituted; R8 is H or C1-C6 alkyl, each R8 being the same or different when two are present; n is 0 or 1; and one of V, W, X and Y is N or CH and the other three are CH; and the pharmaceutically acceptable salts thereof are inhibitors of RSV and can therefore be used to treat or prevent an RSV infection. |
US11634424B2 |
Diazaindole derivative and use thereof as CHK1 inhibitor
Disclosed are a diazaindole derivative as shown in formula I and the use thereof in the preparation of a drug for treating Chk1-related diseases. |
US11634421B2 |
Aryl substituted bicyclic compounds as herbicides
Disclosed are compounds of Formula 1, including all N-oxides, stereoisomers, and salts thereof, wherein Q1, Q2, R1, R2, Y, J and R7 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention. |
US11634417B2 |
Protein tyrosine phosphatase inhibitors
Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. |
US11634414B2 |
Heterocyclic compound and organic light-emitting element including same
Provided is a hetero-cyclic compound of Chemical Formula 1: and an organic light emitting device comprising the same. |
US11634412B2 |
3-phosphoglycerate dehydrogenase inhibitors and uses thereof
The present invention provides compounds, compositions thereof, and methods of using the same. |
US11634406B2 |
Inhibitor of p38 MAP kinase
A compound has the following formula: The compound is a p38 MAP kinase inhibitor. The compound and its pharmaceutically acceptable salts can be used for treatment of conditions, such as inflammatory diseases. |
US11634403B2 |
IRE1 small molecule inhibitors
Provided herein are small molecule inhibitors for the targeting or IRE1 protein family members. Binding may be direct or indirect. Further provided herein are methods of using IRE1 small molecule inhibitors for use in treating or ameliorating cancer in a subject. Moreover, IRE1 small molecule inhibitors described herein are for the treatment of cancer, where the cancer is a solid or hematologic cancer. |
US11634399B2 |
Surfactants from long-chain carbon-containing molecules
Compositions of furan based surfactants derived from unsaturated carbon-containing molecules, such as fatty acids, as well as methods for forming furan based surfactants from unsaturated carbon-containing molecules, such as fatty acids, are disclosed herein. These compositions and methods can utilize long-chain (e.g., C14-C26) unsaturated carbon-containing molecules, for instance unsaturated fatty acids such as oleic acid or methyl oleate from soybean oil, to derive oleo-furan surfactants. To facilitate this, certain such embodiments include reaction steps that cleave the reactant molecule (e.g., methyl oleate) at the double bond and subsequently oxidize products to form a carboxylic acid molecule and a dicarboxylic acid molecule. In such embodiments, these two acids can be subsequently acylated with furan and functionalized to form surfactants. |
US11634398B2 |
Treatment of cancer/inhibition of metastasis
Substances and methods are dislosed for reducing or preventing metastatic behaviour in VGSC expressing cancer by the effect of at least reducing the persistent part of the voltage gated sodium channel current without eliminating the transient part. Inhibition of metastatic cell behaviours such as detachability, lateral motility, transverse migration and invasiveness is demonstrated using the known drugs ranolazine and riluzole. |
US11634390B2 |
Agricultural chemicals
The present invention relates to compounds which are of use in the field of agriculture as herbicides. The invention also relates to methods of using said compounds and compositions comprising said compounds. |
US11634387B2 |
Compounds useful for treating liver diseases
This invention provides compounds, for example, of Formulae (A)-(H) and (J)-(AA) and pharmaceutically acceptable salts, solvates, esters, amides, and prodrugs thereof. The invention further provides pharmaceutical compositions comprising a compound of the invention, and a pharmaceutically acceptable carrier or vehicle. The compounds and compositions disclosed herein are useful for treating or preventing various diseases and conditions, for example liver disease such as liver fibrosis, fatty liver disease, non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH), and kidney diseases such as acute kidney injury (AKI). |
US11634385B2 |
Process for the preparation of haloalkanesulfonic acids from sulfur trioxide and a haloalkane
The present invention relates to a process for preparing haloalkanesulfonic acids from sulfur trioxide and a haloalkane, particularly to a process for preparing trifluoromethane sulfonic acid from sulfur trioxide and trifluoromethane. |
US11634374B2 |
Fluorinated ether compound, fluorinated ether composition, coating liquid, article and its production method
To provide a fluorinated ether compound capable of forming a surface layer excellent in initial water/oil repellency, fingerprint stain removability, abrasion resistance and light resistance; a fluorinated ether composition and a coating liquid containing the fluorinated ether compound; an article having a surface layer excellent in initial water/oil repellency, fingerprint stain removability, abrasion resistance and light resistance and a method for producing it. A fluorinated ether compound having a poly(oxyperfluoroalkylene) chain having a unit (α) which is an oxyperfluoroalkylene unit having 5 or 6 carbon atoms, and a unit (β) which is an oxyperfluoroalkylene unit having at most 4 carbon atoms, and having at least one of a hydrolysable silyl group and a silanol group on at least one terminal of the poly(oxyperfluoroalkylene) chain via a linking group. |
US11634373B2 |
Bisphenol composition and method for producing same, and polycarbonate resin and method for producing same
Provided is a thermally stable bisphenol composition whose increase in the Hazen color number is suppressed even under higher temperature conditions. A bisphenol composition including an aryl alkyl sulfide or a dialkyl disulfide at 0.1 ppb by mass to 1% by mass with respect to a bisphenol. A bisphenol composition including an aryl alkyl sulfide or a dialkyl disulfide at a predetermined ratio is thermally stable in terms of the Hazen color number, and shows no coloring problem under high temperature conditions. By using such a bisphenol composition, a polycarbonate resin having an excellent color tone can be produced. |
US11634370B2 |
Selective hydrogenation methods
The present disclosure relates to methods for selectively hydrogenating acetylene, to methods for starting up a selective hydrogenation reactor, and to hydrogenation catalysts useful in such methods. In one aspect, the disclosure provides a method for selectively hydrogenating acetylene, the method comprising contacting a catalyst composition with a process gas. The catalyst composition comprises a porous support, palladium, and one or more ionic liquids. The process gas includes ethylene, present in the process gas in an amount of at least 20 mol. %; acetylene, present in the process gas in an amount of at least 1 ppm; and 0 to 190 ppm or at least 600 ppm carbon monoxide. At least 90% of the acetylene present in the process gas is hydrogenated, and the selective hydrogenation is conducted without thermal runaway. |
US11634369B2 |
Joint control method for nitrogen and phosphorus emissions in farmlands
The present disclosure provides a joint control method for nitrogen and phosphorus emissions in farmlands, comprising: reducing nitrogen and phosphorus input during crop sowing or planting by applying composite organic material and chemical fertilizer, wherein the composite organic material comprises: 200-250 parts of edible fungi residues, 300-350 parts of charcoal and 5-10 parts of rhamnolipid; constructing a nitrogen-phosphorus retention layer by utilizing composite microbial agent in combination with 150 parts of edible fungi residues and 20 parts of straw-based hydrogel; constructing a barrier layer by utilizing composite material, and controlling downward leaching of nitrogen and phosphorus that are not absorbed by crops, wherein the composite material of the barrier layer comprises: 25-35 parts of straw-based hydrogel, 20-30 parts of edible fungi residues, 35-55 parts of bentonite and 5-10 parts of corn flour. |
US11634367B2 |
Stimulation of the nitrification of a soil with compounds comprising a plant extract
The invention relates to the use of an amendment composition comprising an extract of Cynara leaves for stimulating the nitrification of a soil, a process for stimulating the nitrification of a soil with an amendment composition comprising an extract of Cynara leaves and an amendment composition comprising an extract of Cynara leaves and one or more compound(s) selected from (i) a basic calcium amendment, (ii) a yeast extract, and (iii) an extract of a legume of the family Fabaceae. |
US11634366B2 |
Plant growth enhancer using carbon dioxide to increase plant yield and method of increasing plant yield
A plant growth enhancer including a source of carbon dioxide, a source of carbohydrate, and source of acid in an amount to provide increased retention of carbon dioxide in the soil. A method of enhancing the growth of plants by applying the plant growth enhancer to the soil containing the plant, the acid increasing retention of the carbon dioxide in the soil, and the plant exhibiting enhanced growth from the combination of the carbon dioxide and carbohydrate. |
US11634356B2 |
Glass and melt solder for the passivation of semiconductor components
The disclosure relates to a glass and a melt solder for the passivation of semiconductor components, the use of the glass or the melt solder for the passivation of semiconductor components, a passivated semiconductor component and a method for passivating semiconductor components. |
US11634355B2 |
Ceramic glass powder and solar cell metallization paste containing ceramic glass powder
The present disclosure discloses a ceramic glass powder and a solar cell metallization paste containing the ceramic glass powder, and belongs to the technical field of solar cells. The present disclosure provides a novel formula mode of a glass powder including a crystallization nucleus component and a glass network component, that is, a formula of a ceramic glass powder that has a special crystallization behavior, a low crystallinity before sintering and a high crystallinity after the sintering, and a conductive metallization paste containing the ceramic glass powder is further obtained. The present disclosure solves the technical problem that by using metallization pastes in the prior art, a balance between corrosion of a silicon wafer and an ohmic contact is difficult to achieve. The efficiency of a solar cell is improved. |
US11634354B2 |
Colored glass articles having improved mechanical durability
A colored glass article may include 50-80 mol % SiO2; 7-20 mol % Al2O3; 1-35 mol % R2O, wherein R2O comprises at least one of Li2O, Na2O, and K2O; 1×10−6-10 mol % of a colorant, wherein the colorant comprises at least one of Cr2O3, Au, Ag, CuO, NiO, Co3O4, TiO2, CeO2; and 12-24 mol % of Al2O3+MgO+CaO+ZnO. The colored glass article may have a transmittance color coordinate in the CIELAB color space with an L* value of 55 to 96.5. The colored glass article may have a compressive stress profile with a depth of compression ≥0.15t, a thickness t from 0.4 mm-5 mm, a compressive stress ≥200 MPa, and a central tension ≥60 MPa. The colored glass article may have a dielectric constant from 5.6 to 6.4 over the frequency range from 10 GHz to 60 GHz. |
US11634353B2 |
Glass plate and window
To provide a glass plate for a window material and a window comprising the glass plate, which are less likely to be a barrier to radio transmitting/receiving in use of a radio-utilizing apparatus, and a radio communication apparatus comprising the glass plate.A glass plate having a radio transmittance of at least 20% at a frequency of 100 GHz as calculated as 18 mm thickness, a window comprising the glass plate, and a radio communication apparatus comprising the glass plate. |
US11634350B2 |
Water filter and filter cartridge
A water filter cartridge includes a sediment filter, a carbon filter, and a core having a tubular body with openings that allow water to flow through the core. The core defines an open central area, and the core supports the sediment filter and the carbon filter. A nanofiltration unit is arranged within the open central area of the core. The nanofiltration unit includes a tubular filter element defining a central volume, and a plurality of filaments arranged within the central volume. |
US11634349B2 |
Two-stage biogas production system for anaerobic digesters
A multi-stage system comprising a digester, a bioreactor, a scrubber, a biofilter, and a membrane filter extracts and purifies biogas from a wastewater feed. The digester separates raw biogas from wastewater, the wastewater is then purified with a three-stage bacterial process in a bioreactor. The scrubber receives raw biogas from the digester under pressure, dissolving waste gases and purifying the methane, which can be further condensed and purified in the membrane filter. The bioreactor receives waste gases from the scrubber and membrane filter, with the ammonia portion of the waste gases rising through water from the bioreactor and being converted by annamox bacteria into nitrogen gas. The multiply recycled gas and water feeds produce a biogas having high purity and reduced atmospheric emissions of waste gases. |
US11634348B2 |
System and method for treating hydrocarbon-containing feed streams
A water processing system includes a pretreatment system disposed within the water processing system. The pretreatment system may treat a feed stream including oil and brine and to generate a first brine stream. The pretreatment system includes a first filtration system that may receive the feed stream, the first filtration system may separate the feed stream into a hydrocarbon stream and an intermediate brine stream, the intermediate brine stream includes a plurality of minerals, and the hydrocarbon stream includes water, the oil, and suspended solids. The water processing system also includes a mineral removal system fluidly coupled to and disposed downstream from the first filtration system. The mineral removal system may receive and remove the plurality of minerals from the first brine stream output from the pretreatment system. The mineral removal system includes a first mineral removal unit that may remove a first portion of the plurality of minerals from the first brine stream and to generate a second brine stream. The water processing system also includes a hydrocarbon removal system disposed within the pretreatment system and fluidly coupled to the first filtration system. The hydrocarbon removal system may receive the hydrocarbon stream, to recover the oil, and to generate a recovered oil stream. |
US11634347B2 |
Separable outer enclosure for turbo blower
Provided is an outer enclosure for a turbo blower in which a turbo blower is installed, which includes a housing forming an exterior of the outer enclosure, an outside air inflow chamber which is a space partitioned in one side inside the housing and which communicates with the outside through an outside air inlet, an inverter chamber which is a space partitioned in the other side inside the housing, a motor chamber which is a space partitioned in an upper portion of a space positioned between an inverter chamber and the outside air inflow chamber, and in which a turbo blower including an intake nozzle communicating with the outside air inflow chamber is positioned, and a first refrigerant discharge port is positioned on one side, a refrigerant inflow chamber which is a space in a lower portion of the motor chamber and which communicates with the outside through a refrigerant inlet, in which the upper and lower portions of the inverter chamber are in communication with the motor chamber and the refrigerant inflow chamber, respectively, and the refrigerant inflow chamber is communication with the motor chamber. |
US11634346B2 |
Systems of gas infusion for wastewater treatment
This application relates to a system of treating wastewater wherein an oxygen infusion system is used to supersaturate wastewater before aerobic biological processes, wherein oxygen is transferred to the wastewater free of oxygen bubbles and achieves a reduction in power demand for the aeration process of wastewater. |
US11634343B2 |
Waste liquid treating device and swarf powder recovery device
A waste liquid treating device includes a holding section that holds an adhesion plate, a vertically moving mechanism that moves the holding section vertically, and a peeling mechanism that peels off water-containing swarf from the adhesion plate held by the holding section. The peeling mechanism includes two air nozzles extending in parallel to each other in a horizontal direction with a spacing therebetween and including jet ports formed to face each other, a valve disposed in a piping providing communication between the two air nozzles and an air source, and a control unit that performs control of opening and closing of the valve and control of the vertically moving mechanism for moving the adhesion plate in the vertical direction in the spacing between the two air nozzles. |
US11634339B2 |
Oxide ion conductor and electrochemical device
An oxide ion conductor has a X3Z2(TO4)3 structure, where X is a divalent metal element, Z is a trivalent metal element, and T is a tetravalent metal element, and has a composition expressed by (X1-xAx)3(Z1-yBy)2(T1-zCz)3O12+δ where the element X is Ca, Fe, Gd, Ba, Sr, Mn, and/or Mg, the element Z is Al, Cr, Fe, Mn, V, Ga, Co, Ni, Ru, Rh, and/or Ir, the element T is Si and/or Ge, an element A is La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, and/or Sr, an element B is Zn, Mn, Co, Ru, and/or Rh, and an element C is Si, Al, Ga, and/or Sn, 0≤x≤0.2, 0≤y≤0.2, and 0≤z≤0.2 are satisfied, and δ is a value securing electrical neutrality. |
US11634337B2 |
Chemical process for the manufacture of magnesium bicarbonate from impure reagent including magnesium hydroxide and calcium carbonate
A process for the chemical conversion of contaminated magnesium hydroxide to high purity solutions of magnesium bicarbonate include steps of providing an impure reagent including at least 40% and less than 95% by total weight of total metals of magnesium in a form of solid magnesium hydroxide and at least 10% by weight of total metals of calcium carbonate, combining the impure reagent containing the solid magnesium hydroxide with carbonic acid in water, thereby generating magnesium bicarbonate and water and then filtering out solid calcium carbonate leaving a solution of magnesium bicarbonate in water having a by weight ratio of Mg/(Mg+Ca) in the solution of greater than 95%. Heating and/or drying the magnesium bicarbonate solution produces correspondingly high purity magnesium carbonate. |
US11634336B2 |
Processes for preparing lithium carbonate
There are provided methods for preparing lithium carbonate. For example, such methods can comprise reacting an aqueous composition comprising lithium hydroxide with CO2 by sparging the CO2 the said composition, thereby obtaining a precipitate comprising the lithium carbonate. The methods can also comprise inserting at least a portion of the precipitate into a clarifier and obtaining a supernatant comprising lithium bicarbonate and a solid comprising the lithium carbonate, separating the solid from the supernatant; and heating the supernatant at a desired temperature so as to at least partially convert the lithium bicarbonate into lithium carbonate. |
US11634333B2 |
Boron-containing titanium-based composite powder for 3D printing and method of preparing same
This invention discloses a boron-containing titanium-based composite powder for 3D printing, consisting of 0.5%-2% by weight of titanium diboride and 98%-99.5% by weight of titanium sponge. The invention further discloses a method of preparing such composite powder, where the element boron is introduced to the titanium powder through rapid solidification, which significantly improves the solid solubility of boron in Ti, enabling the introduction of part of the boron into the titanium matrix to form supersaturated solid solutions. The reinforcement phase TiB in the boron-containing titanium-based composite powder prepared herein can be precisely controlled in grain size ranging from the nanometer scale to the micrometer scale through temperature or energy density, thereby preparing the titanium-based composite materials with different sizes of reinforcement phases to meet different mechanical requirements. |
US11634332B2 |
Selenium-doped MXene composite nano-material, and preparation method and use thereof
The present invention discloses a selenium-doped MXene composite nano-material and a preparation method thereof, comprising the following steps: (1) adding MXene and an organic selenium source into a dispersant, and stirring to prepare a dispersion with a concentration of 1 mg/ml to 100 mg/ml; (2) transferring the dispersion into a reaction kettle, then heating, reacting, and then naturally cooling to a room temperature; (3) washing the product obtained in the step (2) with a cleaning agent, then centrifuging to collect a precipitate, and drying the precipitate under vacuum; and (4) placing the sample obtained in the step (3) into a tubular furnace for calcination, introducing protective gas, heating, and then cooling to a room temperature to obtain the selenium-doped MXene composite nano-material. The material prepared by the present invention has high specific surface area, good electrical conductivity, cycle stability performance, rate performance and high theoretical specific capacity. |
US11634331B2 |
Methods for producing advanced carbon materials from coal
A method of producing advanced carbon materials can include providing coal to a processing facility, beneficiating the coal to remove impurities from the coal, processing the beneficiated coal to produce a pitch, and treating the pitch to produce an advanced carbon material such as carbon fibers, carbon nanotubes, graphene, resins, polymers, biomaterials, or other carbon materials. |
US11634327B2 |
SP2-SP3 hybrid crystalline carbon and its preparation process
The present disclosure belongs to the technical filed of new carbon materials and relates to a novel sp2-sp3 hybrid crystalline carbon named Gradia and its preparation process. A novel sp2-sp3 hybrid carbon named Gradia is synthesized using sp2 hybrid carbon as raw materials under high temperature and high pressure. The basic structural units of Gradia are composed of sp2 hybrid graphite-like structural units and sp3 hybrid diamond-like structural units. Gradia disclosed in the present disclosure is a class of new sp2-sp3 hybrid carbon allotrope, whose crystal structure can vary with the widths and/or crystallographic orientation relationships of internal sp2 and/or sp3 structural units. |
US11634326B2 |
Separation and concentration of nitrate from aqueous solutions and gaseous streams
A process for recovering nitric acid or salts thereof, comprising: contacting, in the presence of water, an water-immiscible ionic liquid of the formula [A+][X−], wherein [A+] represents a phosphonium or ammonium cation and [X−] represents a counter anion which is NO3−, an halide anion displaceable by NO3−, or both, with a fluid which contains HNO3 and at least one more mineral acid, or precursors of said acids, and partition, under mixing, said acids between aqueous and organic phases and form nitrate-loaded ionic liquid of the formula [A+][NO3−]z>0.25 where Z indicates a molar amount of nitrate held in the ionic liquid beyond the positions occupied by the nitrate counter ions; separating the so-formed mixture into an organic phase comprising a nitrate-loaded ionic liquid of the formula [A+][NO3−]z>0.25 and an aqueous phase consisting of a nitrate-depleted aqueous solution that contains the other mineral acid(s); stripping the nitric acid from said nitrate-loaded ionic liquid to create an aqueous nitrate solution and regenerate ionic liquid of the formula [A+][NO3−]z≥0 with reduced nitrate loading, or unloaded [A+][NO3−]z=0 ionic liquid. |
US11634323B2 |
Systems and methods for processing gases
The invention includes a gas processing system for transforming a hydrocarbon-containing inflow gas into outflow gas products, where the system includes a gas delivery subsystem, a plasma reaction chamber, and a microwave subsystem, with the gas delivery subsystem in fluid communication with the plasma reaction chamber, so that the gas delivery subsystem directs the hydrocarbon-containing inflow gas into the plasma reaction chamber, and the microwave subsystem directs microwave energy into the plasma reaction chamber to energize the hydrocarbon-containing inflow gas, thereby forming a plasma in the plasma reaction chamber, which plasma effects the transformation of a hydrocarbon in the hydrocarbon-containing inflow gas into the outflow gas products, which comprise acetylene and hydrogen. The invention also includes methods for the use of the gas processing system. |
US11634319B2 |
Device and method for monitoring surface condition of contact surface of detected object
A surface monitoring device is for monitoring a contact surface of a detected object. The surface monitoring device and the detected object are disposed on a substrate. The surface monitoring device includes a resonant mechanical part, having a contact tip adjacent to the contact surface by a preset gap in a static state. A driving circuit, applying an AC input signal to drive the resonant mechanical part to cause the contact tip to vibrate with respect to the contact surface at a plurality of sampling frequencies. The contact tip substantially hits the contact surface in a tapping bandwidth within the sampling frequencies. An analysis circuit to analyze a ratio of an output voltage to an input voltage of the input signal and determine the tapping bandwidth, wherein the ratio in the tapping bandwidth is jumping to a flatten phase. |
US11634317B2 |
Composite spring for robust piezoelectric sensing
A micro-electromechanical system (MEMS) device comprises a fixed portion and a proofmass suspended by at least one composite beam. The composite beam is cantilevered relative to the fixed portion and extends between a first end that is integrally formed with the fixed portion and a second distal end. The composite beam comprises an insulator having a top surface and at least two side surfaces; a conductor extending away from the fixed portion and surrounding at least a portion of the insulator; and a second conductor positioned adjacent to the top surface of the conductor and extending parallel with the insulator away from the fixed portion. The second conductor is separated from the first conductor to provide a low parasitic conductance of the composite beam. |
US11634316B2 |
Fuel storage and supply arrangement having fuel conditioning assembly
A fuel storage and supply arrangement serves as a source of fuel to be dispensed via at least one fuel dispenser in a fuel dispensing environment. The arrangement comprises a storage tank for containing a quantity of the fuel. A pump assembly draws the fuel from the storage tank providing the fuel under pressure to a fuel supply line. A fuel conditioning assembly includes a housing having a storage volume, a housing inlet receiving the fuel under pressure created by the pump assembly, a housing outlet through which fuel exits the housing, and a housing port through which fuel can be drawn into the housing. A vacuum source in fluid communication with the housing outlet is operative to selectively apply a vacuum to the outlet of the housing so that liquid can be drawn into the housing via the port. A water intake device is in fluid communication with the housing port. The water intake device has at least one inlet situated adjacent to a bottom of the fuel storage tank. |
US11634315B2 |
Machine for distributing a liquid or pasty product
Machine (1) for distributing a product stored in a container (30) comprising a storage zone (2) delimiting locations (4) for housing a container (30), a metering station (5) delimiting a chamber (6) housing a support (7) for accepting a collecting vessel (33), this support (7) being positioned vertically in line with an opening (8) providing access to the chamber (6), which opening is arranged in an upper part (61) of the chamber (6), the machine (1) further comprising a system (10) for emptying each location (4) for housing a container (30) through the opening (8) providing access to the chamber (6), and a unit (14) for controlling the machine (1). The metering station (5) comprises a sensor (13) for detecting the presence of a collecting vessel (33) inside said chamber (6). The control unit (14) is configured to operate the machine (1) on the basis of data supplied by said sensor (13), and the metering station (5) is equipped with a circuit (15) for the circulation of gaseous fluid providing communication between the chamber (6) and the outside of said chamber (6) through a forced circulation of air. |
US11634312B2 |
Refrigeration systems for rapidly cooling food and drinks
Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks. Some machines include a refrigeration system to cool food or drink in a pod. The machines include an evaporator defining a receptacle sized to receive the pod. The evaporator includes an inlet port to receive refrigerant and an outlet port to discharge refrigerant. |
US11634310B2 |
Container filling assembly
A container filling assembly that can be used with container filling systems to fill containers during successive filling cycles with the same or different fluid compositions at high rates of speed, with little to no machinery changeover, and/or with little to no fluid waste. |
US11634305B2 |
Coordinated safety interlocking systems and methods
Accordingly, exemplary embodiments are disclosed of coordinated safety interlocking systems and methods of coordinating safety interlocking. In an exemplary embodiment, a system for providing coordinated safety interlocking between a plurality of machines is disclosed. The system generally includes a plurality of machine control units each configured to control at least one of the plurality of machines. The system also includes at least one operator control unit configured to define a dynamic cluster including a subset of the plurality of machine control units. The at least one operator control unit is configured to control safety interlocking between each machine control unit in the dynamic cluster. The system may be used to provide coordinated safety interlocking between various elements and/or machines, such as crane bridges and crane hoists, etc. |
US11634304B2 |
Elevator renewal method and elevator auxiliary panel
An elevator renewal construction method includes steps of: replacing an old control panel of an existing elevator with a new control panel; installing an auxiliary panel, which includes a communication converter to be connected to the new control panel, and which is formed separately from the new control panel; and connecting an old device including at least any one of an old hall device and an old car device, which has been placed in a communicable state with the old control panel of the existing elevator, into a communicable state with the new control panel via the communication converter, wherein the new control panel is configured to be communicable with the old device through an old communication system converted via the communication converter included in the auxiliary panel, the communication converter being configured to mutually convert a communication system between a new communication system and the old communication system. |
US11634299B2 |
Wire reels, components thereof, and related methods
Embodiments provide reels comprising covers, wire hubs, and winding levers. The covers removably attach to casings and close spool apertures of the casings. The hubs spool wire into/out of the apertures via windows of the casings. Moreover, the hubs couple to the covers. Some levers operably couple to the covers. When stowed, the levers are within the perimeters of the covers. When deployed, the levers extend beyond the perimeters. The reels can also comprise the casings. Mounting bases of some reels can removably attach to the casings. Furthermore, some levers can pivot about hinges on the covers. Levers can comprise wind knobs at their ends and the covers can define apertures through which the knobs extend when stowed. Detents which retain the levers in the stowed position can be provided. Moreover, hubs can comprise the detents for engaging the levers when the levers are stowed. |
US11634298B2 |
Horizontal wire feed spool delivery system
Disclosed are systems and methods for feeding welding wire for welding-type applications. The wire-feeder system comprises a base platform, a spool hub, a drive roll assembly, and a wire guide assembly. The spool hub can be mounted to the base platform perpendicular to the base platform and configured to support a wire spool. The drive roll assembly can be mounted to the base platform, and having one or more sets of drive rollers configured to feed wire from the wire spool toward a welding torch. The wire guide assembly can be mounted to the base platform separately from both the wire spool and the drive roll assembly. |
US11634294B2 |
Sheet-feeding device and sheet-feeding method
A first shaft control section is configured to control rotation of a first support shaft supporting a first roll such that a sheet is unwound from the first roll at a predetermined running speed. A second shaft control section is configured to execute a first rotation control of regulating a rotational speed of a second support shaft supporting a second roll such that a peripheral speed of the second roll coincides with the predetermined running speed of the sheet of the first roll. The second shaft control section is configured to regulate the rotational speed of the second support shaft by acceleration or deceleration such that an adhesive on an outer peripheral surface of the second roll arrives at a pressing position when a target joining portion of the sheet of the first roll meets the pressing position. |
US11634292B2 |
Sheet conveyance apparatus and image forming apparatus
A sheet conveyance apparatus includes a conveyance unit configured to convey a sheet, a guide member disposed to define a conveyance path, a light-emitting element, a light-receiving element configured to output a detection signal that changes in accordance with an amount of received light, a first light-passing portion disposed to define an optical path from the light-emitting element to the conveyance path, and a second light-passing portion disposed to define an optical path from the conveyance path to the light-receiving element. The light-receiving element is configured such that the detection signal changes in accordance with whether or not a sheet is present in the conveyance path. Reflectance of each of the first light-passing portion and the second light-passing portion to the light emitted from the light-emitting element is higher than reflectance of the guide member to the light emitted from the light-emitting element. |
US11634291B2 |
Belt conveyance device, sheet feeding device, image forming apparatus, and image forming system
A belt conveyance device includes an endless belt, a duct having a suction port, and a rectifier inside the duct. The duct is surrounded by an inner circumferential surface of the endless belt. The rectifier extends in a width direction of the endless belt perpendicular to a direction of conveyance by the endless belt. |
US11634290B2 |
Sheet conveyance apparatus and image forming apparatus
A sheet conveyance apparatus includes a receiving member to hold a sheet pressing portion and receive a reaction force of an urging portion for urging the sheet pressing portion toward the first sheet guide, a detection unit having a first detection portion disposed on a first sheet guide, and a second detection portion facing the first detection portion and disposed on a second sheet guide. The detection unit changes an output value based on presence and absence of the sheet at a detection position in a sheet conveyance path, wherein the second guide provided with the second detection portion, and a receiving member are movably disposed with respect to the first guide provided with the first detection portion respectively, and are positioned with respect to the first guide independently from each other, and wherein the receiving member is pivotably supported around the pivot axis independently from the second guide. |
US11634289B2 |
Image-forming apparatus having electromagnetic clutch for transmitting drive force of motor to conveying roller
In an image-forming apparatus, when a sheet length of a first sheet is shorter than or equal to a predetermined length, a controller supplies power to an electromagnetic clutch to convey the first sheet and a second sheet so that a sheet gap of the second sheet is equivalent to a first gap. When the sheet length of the first sheet is longer than the predetermined length, the controller supplies power to the electromagnetic clutch to successively convey a first number of sheets so that the sheet gap of each of the first number of sheets is equivalent to the first gap. After the first number of sheets has been conveyed, the controller supplies power to the electromagnetic clutch to convey at least one sheet so that the sheet gap of each of the at least one sheet is equivalent to a second gap greater than the first gap. |
US11634287B2 |
Drive mechanism capable of dealing with gas sterilization
Provided is a drive mechanism capable of withstanding sterilization treatment using a sterilization gas such as hydrogen peroxide and capable of performing positioning operation with heightened accuracy. In a drive mechanism according to the invention, a movable block disposed in the internal space of a partition wall for blocking a sterilization gas is coupled to a movable platform disposed in the external space of the partition wall by means of a magnet coupling mechanism. Further, biasing magnet units are disposed on surfaces, of the movable block and the movable platform, on which no magnet coupling mechanism is disposed, such that the biasing magnet units serve as magnetic poles repelling each other. Repelling force generated by the biasing magnet units serves as biasing force that biases the movable platform toward the partition wall. |
US11634285B2 |
Conveyor with guide rails to support a divert unit
A conveyor that includes a conveyor frame, a first guide rail assembly, a divert unit having a switch assembly, and an alignment key is described. In this regard, the first guide rail assembly is positioned on a first portion of the conveyor frame such that rails of the first guide rail assembly extends along a length of the conveyor. In some examples, the first guide rail includes a first guide rail and a second guide rail positioned parallel to the first guide rail. Further, the first guide rail defines a groove along a length of the first guide rail assembly. Furthermore, according to some examples, the switch assembly defines a key slot. The key slot is adapted to enable the alignment key to pass through the key slot and further into the groove of the first guide rail, thereby, aligning the switch assembly on the first guide rail. |
US11634283B2 |
Paddle conveyor system
A paddle conveyor system for efficiently removing tare, dirt, small particles, and other debris from large bulky products such as sugar beets. The paddle conveyor generally includes a first pulley including a first side and a second side and a second pulley including a first side and a second side. A first linkage is connected between the first side of the first pulley and the first side of the second pulley and a second linkage is connected between the second side of the first pulley and the second side of the second pulley. A plurality of paddles is each connected between the first linkage and the second linkage such that the plurality of paddles forms a loop for conveying a material towards the second pulley. Each of the paddles includes one or more slots through which debris from the material may fall. |
US11634279B2 |
Storage and retrieval system
An automated storage and retrieval system including at least one autonomous transport vehicle, a transfer deck that defines an undeterministic transport surface for the at least one autonomous transport vehicle, the transfer deck having multiple travel lanes, at least one vertically reciprocating lift, and at least one pickface handoff station connected to the transfer deck and interfacing between the at least one autonomous transport vehicle on the transfer deck and the at least one vertically reciprocating lift so that a pickface is transferred between the at least one vertically reciprocating and the at least one autonomous transport vehicle. |
US11634270B2 |
Utility box with angled floor
Provided is a utility box, which includes a first compartment. The first compartment includes a first angled floor and a first holding unit configured to hold an article in the first compartment. The utility box also includes a first lid that covers at least the first compartment. |
US11634269B1 |
Spray foam insulator assembly
A spray foam insulator assembly for retaining a pressurized can of spray foam at a preferred temperature includes an insulating sleeve that has a diameter of at least 68.0 mm and a height of at least 245.0 mm to insertably receive a pressurized can of spray foam. The insulating sleeve is comprised of a thermally insulating material to retain the pressurized can of spray foam at an optimal temperature for enhancing functionality of the pressurized can of spray foam. The insulating sleeve has a cut integrated into the insulating sleeve to enhance inserting the pressurized can of spray foam into the insulating sleeve. A closure is integrated into the insulating sleeve for opening and closing the cut. A belt clip is coupled to the insulating sleeve to engage an article of clothing on a user for storing the insulating sleeve. |
US11634266B2 |
Thermally insulated shipping system for parcel-sized payload
Shipping container for a temperature-sensitive payload. In one embodiment, the shipping container includes an insulated base having a bottom wall and four side walls. A first thermally conductive member is positioned on the bottom wall. A payload box is centered on top of the first thermally conductive member, and four frozen packs, each having a thickness matching the height of the payload box, are positioned along the four sides of the payload box. An insulating frame may be placed around the payload box to keep the frozen packs from directly contacting the payload box. A second thermally conductive member is positioned on top of the payload box and the four frozen packs, and an insulated lid is positioned on top of the second thermally conductive member and the four side walls of the base. One, both or neither of the thermally conductive members may be removed to optimize seasonal suitability. |
US11634258B2 |
Cover for drug product bottles
The cover for a drug product bottle with transfer tubes extending therefrom. The cover is made with two parts that close on each other over a screw cap on a drug product bottle. The parts each have a ledge that fits under the screw cap, an intermediately disposed flange that rests on the screw cap and a semi-circular lid spaced from the flange. The flanges and lids define an encapsulated space when the parts are in a closed position to encapsulate the transfer tubes extending from the bottle. |
US11634257B2 |
Lyophilization container and method of using same
Provided is a multi-part lyophilization container for lyophilizing a fluid, storing the lyophilizate, reconstituting the lyophilizate, and infusing the reconstituted lyophilizate into a patient, including a method of using same. The container includes a front surface, a back surface, a non-breathable section including a port region, a breathable section including a breathable membrane, and an occlusion zone encompassing a boundary between the non-breathable section and the breathable section. The non-breathable section is configured to accommodate any of a liquid, a solid, a gas or combination thereof. The breathable section is configured to accommodate only a gas. The method includes creating a temporary seal between the non-breathable section of the container and the breathable section, inputting a liquid into the non-breathable section, freezing the liquid, removing the temporary seal to allow vapor transport between the non-breathable section and the breathable section, and adding heat energy the frozen liquid under vacuum. |
US11634256B2 |
Flow control insert
A flow control insert (102) for a dispensing closure is provided. The insert has a plurality of dispensing slits (that define petals. (120,122,124,126). The petals are formed in an open position and are closed upon assembly of the insert into a dispensing closure. |
US11634255B1 |
Condiment bottle
A condiment bottle includes a container and cap assembly. The cap assembly includes a securing part releasably connected to the container, a nozzle secured to the container by the securing part, and a closure part connected to both the securing part and the nozzle. The closure part is configured to move along a longitudinal axis of the condiment bottle from a closed position where the closure part sealingly engages the nozzle to an intermediate position where the closure part is spaced from and covering the top of the nozzle. The closure part is further configured to pivotally move from the intermediate position to an open position where the closure part is located along a sidewall of the nozzle. |
US11634249B2 |
Slide-open dispenser package for loose articles
A slide-open dispenser package for loose articles including: a container for containing a plurality of loose articles, in which the container includes a bottom wall and an article dispensing outlet opening made in the bottom wall; a wrapper on the outside of the container and slidably coupled thereto along a sliding direction orthogonal to the bottom wall; at least one occluding element for occluding the outlet opening, in which the occluding element is movable between a closed configuration, in which it prevents the articles from coming out of the opening, and an open configuration, in which it allows at least one article to come out through the outlet opening. The occluding element is fixed to the container and to the wrapper so that the reciprocal sliding of the wrapper and the container causes the occluding element to move between the closed configuration and the open configuration. |
US11634247B2 |
Bottle
A bottle includes a bottom portion which includes a bottom wall portion with a grounding portion located at an outer circumferential edge thereof, and a tubular heel portion extending upward from an outer circumferential edge of the grounding portion, in which the bottom wall portion includes an inner circumferential wall portion extending upward from an inner circumferential edge of the grounding portion, and a recessed wall portion extending inward in a radial direction from an upper end of the inner circumferential wall portion, a plurality of concave portions or a plurality of convex portions are formed on the inner circumferential wall portion over the entire circumference, and the plurality of concave portions or the plurality of convex portions are located at a portion in the inner circumferential wall portion including at least a lower end edge of the inner circumferential wall portion. |
US11634238B1 |
Cart with wheels oriented in different directions
In an embodiment, a system includes a frame configured to support a load, a first set of wheels provided on the frame, a second set of wheels provided on the frame, and a controller. The first set of wheels is configured to descend or ascend in response to the controller, and is oriented to move in a first direction. The second set of wheels is configured to descent or ascend in response to the controller, and is oriented to move in a different direction from the first direction. The controller configured to control the descent and ascent of the second set of wheels and the first set of wheels. |
US11634235B1 |
Electrically powered rotorcraft capable of autorotative landing
A method of operating an electrically powered rotorcraft of the type having a fuselage and a set of N rotors driven by a set of electric motors and coupled to the fuselage, N≥4, under a failure condition preventing ordinary operation of the rotorcraft. The method includes entering a failsafe mode of operation wherein autorotation of at least four of the rotors is enabled. The method also includes using electrical braking associated with a selected group of the rotors to control yaw of the rotorcraft. |
US11634234B2 |
Electrical power systems
Electrical power system includes: one or more rotary electric machines, each mechanically coupled to a gas turbine engine spool; a set of converter circuits connected to the one or more rotary electric machines for conversion between alternating (ac) and direct current (dc), wherein one or more rotary electric machines and the set of converter circuits are arranged to output a number R≥2 of dc power channels, each dc power channel having a respective index r=(1, . . . , R); and a group of N dc load channels connected to the R dc power channels by a switching arrangement, wherein N>R and each dc load channel has a respective index n=(1, . . . , N). The switching arrangement is operable to connect a number Q≥1 of the N load channels to at least two different power channels of the R power channels. |
US11634228B2 |
High volume flow management of cooling air
A flow management system for delivering air to a heat load of an aircraft includes a cover having an opening for receiving and directing an airflow, and a duct defining a non-linear fluid flow path. The fluid flow path operably couples the opening and the heat load. A configuration of the fluid flow path reduces a velocity of the airflow therein while minimizing a pressure drop of the airflow. |
US11634219B2 |
Stackable swarming drones having a mating recess structure
The present invention provides a stackable drone and a drone swarm comprising at least two stackable drones. Each drone comprising: a fuselage comprising a first end and a second end; a mating structure arranged in the fuselage and configured to have an opening at the first end of the fuselage, the mating structure forming a mating recess on a first side of the fuselage, the mating recess having an opening at the first side of the fuselage for receiving a mating projection from a further stacking unmanned aerial vehicle. The stackable drones do not require a large area of ground for take-off and landing, require only a small space for storage and transportation. When landing, based on the conical or pyramidal structure, the drone may slide down by gravitational force into the mating recess of another drone thereunder without needs of high precision positioning or alignment system. |
US11634218B2 |
Redundant drive train for pylon mounted rotors
A system includes an inboard tiltrotor subsystem and an outboard tiltrotor subsystem. The inboard tiltrotor subsystem includes an inboard pylon, an inboard tiltrotor, and a single and non-redundant drivetrain. The outboard tiltrotor subsystem includes an outboard pylon that is coupled to a wing and an outboard tiltrotor. The outboard tiltrotor has a range of motion and is coupled to the wing via the outboard pylon, such that the outboard tiltrotor is aft of the wing. The outboard tiltrotor subsystem further includes a redundant drivetrain (which has a plurality of motors and a plurality of motor controllers) that drives one or more blades and the one or more blades. |
US11634214B1 |
Drones with sensors used in insurance applications
Drones are engineered with sensors for use in insurance applications. After locating an object of interest, a drone performs an investigation by probing the object of interest. Sensors receive feedback from the object of interest. An electronic fingerprint of the drone is produced. Afterward, perils are computed based on the feedback and the fingerprint of the drone is used in insuring the object of interest. The act of probing includes thumping, drumming, or radiating ultrasound waves against the object of interest. The sensors can be turned off when they are within a geographic zone of prohibited operations. |
US11634213B2 |
High temperature oxidation protection for composites
An oxidation protection system disposed on a substrate is provided, which may comprise a boron layer comprising a boron compound disposed on the substrate; a silicon layer comprising a silicon compound disposed on the boron layer; and at least one sealing layer comprising monoaluminum phosphate and phosphoric acid disposed on the silicon layer. |
US11634210B2 |
Dynamic axial preloading with flexure plate
A system for an unmanned aerial vehicle can include an altitude control system, which further includes a compressor assembly, a valve assembly, and an electronics assembly. The compressor assembly may include a driveshaft and a bearing assembly configured to rotate the driveshaft. The driveshaft may be formed from a first material and a compressor housing may be formed from a second material. The first and second materials may have different rates of thermal expansion. A dynamic preloading mechanism, such as a flexible plate, may be provided within the compressor assembly to exert a preloading force on the bearing assembly. Throughout the duration of the flight of the unmanned aerial vehicle, the preloading mechanism can continually compensate for differences in rates of thermal expansion between the first and second materials throughout. |
US11634207B2 |
Variable waterline for horizontal pressure deck
A pressure deck system for a fuselage of an aircraft. The pressure deck system comprises a first sloping outboard pressure panel, a first longitudinal stiffener connected to the first sloping outboard pressure panel, a second sloping outboard pressure panel opposite the first sloping outboard pressure panel, a second longitudinal stiffener connected to the second sloping outboard pressure panel, pressure panels between the first sloping outboard pressure panel and the second sloping outboard pressure panel and forming the an upper barrier of a wheel well, longitudinal beams connected to the pressure panels and supporting a cabin floor of the fuselage, and a sloping pressure deck connecting a number of these components to the rear spar of the center wing box. A waterline of the pressure deck system is de-coupled from a side-of-body waterline in the fuselage. |
US11634204B2 |
Boat
A boat includes a boat body, a propulsion device, an operator that operates the propulsion device, and a controller. The propulsion device is disposed in the boat body and generates a propulsion force to move the boat body. The controller executes an automatic shore arrival control to control the propulsion device so as to cause the boat body to move toward a target position. The controller ends the automatic shore arrival control when the operator is positioned in a non-neutral position that differs from a neutral position. |
US11634203B2 |
In-port ship exhaust capture device
A device for capturing in-port ship exhaust gases is designed to be connected to a ship, when the ship has at least one funnel that serves as an outlet for exhaust gases. The device includes at least one collection device, including a hood designed to connect to the funnel at the exhaust outlet so as to collect the exhaust gases coming out of the funnel, a handling unit designed to move the collection device and position it at the exhaust outlet, a first constraint configured to interconnect or disconnect the collection device and the handling unit by command so as to create a handling configuration in which the collection device and the handling unit are interconnected by the first constraint and can be moved as one, and a collection configuration in which the collection device collects the exhaust gases and the connection achieved by the first constraint is released, and a second constraint configured to exert a magnetic attraction force, by command, intended to put the first constraint into the handling configuration. |
US11634201B1 |
Marine drives and idle relief exhaust systems for marine drives
A marine drive is configured to propel a marine vessel in a body of water. The marine drive has an engine; a primary exhaust conduit receiving exhaust gases from the engine and discharging the exhaust gases to a primary exhaust outlet discharging the exhaust gases to the body of water; an idle relief exhaust outlet discharging exhaust gases to atmosphere, above the body of water; a primary idle relief muffler receiving exhaust gases from the primary exhaust conduit; a secondary idle relief muffler receiving exhaust gases from the primary idle relief muffler; and a tertiary idle relief muffler configured to receive exhaust gases from the secondary idle relief muffler and discharges exhaust gases to atmosphere via the idle relief exhaust outlet. |
US11634199B2 |
Hull device
Disclosed is a hull device designed to be reversibly attached to an outer surface of a ferromagnetic structure of a marine or submarine system or vessel. The device includes at least one attachment surface suitable for attaching the device to the structure, and a plurality of permanent magnets arranged in the vicinity of the attachment surface in order to attach the device to the structure. |
US11634196B2 |
Straddle seat assembly
A straddle seat assembly having a backrest and a straddle seat is disclosed. The straddle seat has a base structure that has an upper surface to which a resiliently deformable top portion is connected. The resiliently deformable top portion covers at least partially the upper surface. The backrest is selectively connected to the resiliently deformable top portion at either one of at least two positions along a length of the straddle seat such that deformation of the top portions permits movement of the backrest. A personal watercraft having the straddle seat assembly is also disclosed. |
US11634193B2 |
Automatic locking/unlocking system for traction systems, actuated by pedal levers
A locking/unlocking system for traction systems actuated by pedal levers, which includes: a blocking element (1); a receiving element (10); an automatic activation means (3) for coupling and uncoupling the blocking element (1) of the receiving element (10); at least, a control means (16) for controlling the automatic activation means (3); at least, a switch (15a, 15b) for turning the control means on and/or off (16); and at least, a power source (17).A pedal lever (9) for traction systems actuated by pedal levers, which includes: a locking/unlocking system, in accordance with this invention.A traction system actuated by pedal levers, which in turn includes: a pedal lever (9) in accordance with this invention on each of the two ends of the central axis (8), which is introduced and fastened to the adapter (7) of the freewheel (6), or directly onto the freewheel (6) of the lever (9). |
US11634192B2 |
Bicycle handlebar
The utility model discloses an improved bicycle handlebar, including a handlebar tube and a handlebar head. The handlebar head includes a curved arm and grips. The curved arm is of a structure that inclines forward relative to the handlebar tube. The grips naturally stretch along two ends of the curved arm toward the left and right sides. The handlebar tube is provided with a positioning groove and a limiting hole, a support tube is provided with a positioning protruding portion. After the handlebar tube is inserted into the support tube, the positioning protruding portion is inserted into the positioning groove to ensure that the handlebar will not rotate by itself. Screw the limit screw into the limiting hole to prevent the handlebar from being too deep to pull out. The handlebar is designed to be of a structure, which is more comfortable to use. |
US11634191B2 |
Electric motorcycle with novel swing arm configuration
The present invention is generally directed to a swing arm configuration and, more specifically, a swing arm that is supported by a shaft of a motor, such as an electric motor of a motorcycle. The configuration includes a swing arm assembly that is supported by a shaft of a motor at one end and a rear axle at the other end. Advantageously, the shaft of the motor may be a structural component of an electric motorcycle and serve as the swing arm pivot as well as the drive shaft. |
US11634190B2 |
Cargo bicycle conversion system
The present disclosure relates generally to bicycles, in particular, the present disclosure provides systems and devices for converting a standard bicycle into a cargo bicycle using various detachable components. The ability to convert a standard bicycle into a cargo bicycle and back again confers many advantages, including eliminating the need for a separate bicycle for transporting cargo and encouraging the use of bicycles as a mode of transportation. |
US11634189B2 |
Battery arrangement structure and saddle-riding type vehicle
Various battery arrangement structures are presented for a saddle-riding type vehicle. An arrangement can be configured to protect a battery from external impact, and can include a pair of left and right rear frames disposed at the rear section of the vehicle with a battery disposed between the pair of left and right rear frames. The pair of left and right rear frames include a pair of left and right first rear frames and a pair of left and right second rear frames. A power unit-supporting portion which swingably supports a power unit is provided at rear portions of the pair of left and right rear extension portions, and the battery is disposed between the pair of left and right second rear frames and above the power unit-supporting portion. |
US11634185B2 |
Sport utility vehicle storage system
A vehicle storage system may include a deck configured to span substantially a total width of a vehicle bed, and a drawer assembly including a supporting frame and a tub, the drawer assembly configured to extend, via a guide channel assembly, in a longitudinal direction of the vehicle bed past the deck, and configured to retract, via the guide channel assembly, under the deck, the drawer assembly configured to detach from the guide channel assembly and be removed from the vehicle bed, the deck configured to rotate between a closed position and an open position relative to the drawer assembly. The vehicle storage system may further include a cart affixed to a bottom portion of the drawer assembly. |
US11634180B2 |
Vehicle body rear part structure
The disclosure provides a vehicle body rear part structure. The vehicle body rear part structure includes a load support part on a quarter pillar. The load support part includes a side sill stiffener, a quarter pillar stiffener and a damper stiffener. The side sill stiffener reinforces a side sill and forms a part of the quarter pillar. The quarter pillar stiffener is provided continuously with the side sill stiffener and reinforces the quarter pillar. The damper stiffener is provided above a rear wheel house and joined to the quarter pillar stiffener and a roof side rail. |
US11634174B2 |
Coaxial co-located vehicle drive power and steering system
A coaxial co-located vehicle power drive and steering system includes a motor coupled to a transmission having a drive shaft with a first portion and a second portion mechanically interlocked by a spline having corresponding meshing features extending parallel to the drive shaft longitudinal axis. A drive shaft housing enclosing at least a length of the drive shaft, the drive shaft housing including a first portion and a second portion mechanically interlocked by a spline having corresponding meshing features extending parallel to the drive shaft longitudinal axis. A distal end of the drive shaft terminating within a differential gearbox in mechanical communication with an axle. A steering system coupled to the drive shaft housing second portion, the steering system including one or more rotatable gears which cause an angular rotation of the housing in relation to the drive shaft. |
US11634164B2 |
Operation selection device deciding on vehicle operation using weighting
An operation selection device includes a memory and a processor. The processor is configured to perform communication between a self-driving device provided at a vehicle which performs self-driving, and a plurality of operating devices that enable the vehicle to be driven remotely via a remote-control operation performed by a remote-control driver, and that are individually provided for each of a plurality of remote-control drivers, and to acquire information relating to remote-control operations performed by each remote-control driver using each of the plurality of operating devices for a receiving remote-control operation in the vehicle currently being driven remotely, using a predetermined weighting, one remote-control operation among many acquired remote-control operations, and to output information related to remote-control operation that has been decided on to the vehicle, and to allocate a score, which is reflected in the weighting, to the remote-control driver who performed the remote-control operation that has been decided. |
US11634163B2 |
Producing, for an autonomous vehicle, a route from an origination to a destination
Candidate routes, from an origination to a destination, can be produced. Information can be obtained. The information can be of likelihoods of encounters, along the candidate routes, with types of driving situations demonstrated to cause changes in a degree of confidence, of an occupant of an autonomous vehicle, that a controller of the autonomous vehicle will be able to control the autonomous vehicle so that a result of the encounters is not a collision. Take-over probabilities can be obtained. The take-over probabilities can be of likelihoods that the occupant, in response to the encounters, will cause control of the autonomous vehicle to be transferred to the occupant. Based on the information and take-over probabilities, a route from the origination to the destination can be selected from the candidate routes. The autonomous vehicle can be caused to be configured to commence to move in a direction in accordance with the route. |
US11634162B2 |
Full uncertainty for motion planning in autonomous vehicles
Systems and methods for motion planning by a vehicle computing system of an autonomous vehicle are provided. The vehicle computing system can input sensor data to a machine-learned system including one or more machine-learned models. The computing system can obtain, as an output of the machine-learned model(s), motion prediction(s) associated with object(s) detected by the system. The system can convert a shape of the object(s) into a probability of occupancy by convolving an occupied area of the object(s) with a continuous uncertainty associated with the object(s). The system can determine a probability of future occupancy of a plurality of locations in the environment at future times based at least in part on the motion prediction(s) and the probability of occupancy of the object(s). The system can provide the motion prediction(s) and the probability of future occupancy of the plurality of locations to a motion planning system of the autonomous vehicle. |
US11634161B2 |
Path planning using delta cost volume generated from movement restrictions and observed driving behavior
In one embodiment, a method includes determining an initial cost volume associated with a plurality of potential trajectories of a vehicle in an environment based on a set of movement restrictions of the vehicle, generating a delta cost volume using the initial cost volume and environment data associated with the environment, wherein the delta cost volume is generated by determining adjustments to the initial cost volume that incorporate observed driving behavior, and scoring a trajectory of the plurality of potential trajectories for the vehicle based on the initial cost volume and the delta cost volume. |
US11634156B1 |
Aerial view generation for vehicle control
This application is directed to aerial view generation for vehicle control. A vehicle obtains a forward-facing view of a road captured by a front-facing camera of a vehicle and applies a machine learning model to process the forward-facing view to predict determine a trajectory of the vehicle and a road layout based on a Frenet-Serret coordinate system of the road for the vehicle. The trajectory of the vehicle is combined with the road layout to predict an aerial view of the road, and the aerial view of the road is used to at least partially autonomously drive the vehicle. In some embodiments, the machine learning model is applied to process the forward-facing view to determine a first location of each of an obstacle vehicle in the Frenet-Serret coordinate system. The first location of the obstacle vehicle is converted to a vehicle location on the aerial view of the road. |
US11634153B2 |
Identification of proxy calibration targets for a fleet of vehicles
Example embodiments relate to identification of proxy calibration targets for a fleet of sensors. An example method includes collecting, using a sensor coupled to a vehicle, data about one or more objects within an environment of the vehicle. The sensor has been calibrated using a ground-truth calibration target. The method also includes identifying, based on the collected data, at least one candidate object, from among the one or more objects, to be used as a proxy calibration target for other sensors coupled to vehicles within a fleet of vehicles. Further, the method includes providing, by the vehicle, data about the candidate object for use by one or more vehicles within the fleet of vehicles. |
US11634152B2 |
Systems and methods for providing a suggested steering action indicator to user interface of vehicle
Systems and methods are provided to provide a steering indicator to a driver of a vehicle. It is determined whether a first obstacle is in a forward path of the vehicle and whether a second obstacle is present at a side of the vehicle. In response to (a) determining the first obstacle is in the forward path and (b) determining whether the second obstacle is present at the one or more sides of the vehicle, a suggested steering action indicator indicating one or more movements for the vehicle to avoid the first obstacle is provided to a user interface of the vehicle. |
US11634149B2 |
Method of using a single controller (ECU) for a fault-tolerant/fail-operational self-driving system
In a self-driving autonomous vehicle, a controller architecture includes multiple processors within the same box. Each processor monitors the others and takes appropriate safe action when needed. Some processors may run dormant or low priority redundant functions that become active when another processor is detected to have failed. The processors are independently powered and independently execute redundant algorithms from sensor data processing to actuation commands using different hardware capabilities (GPUs, processing cores, different input signals, etc.). Intentional hardware and software diversity improves fault tolerance. The resulting fault-tolerant/fail-operational system meets ISO26262 ASIL-D specifications based on a single electronic controller unit platform that can be used for self-driving vehicles. |
US11634148B2 |
Method, apparatus, storage medium and electronic device for testing dynamic parameter of vehicle
A method, an apparatus, a storage medium, and an electronic device for testing dynamic parameter of vehicle are provided. The method for testing dynamic parameter of vehicle provided by the present disclosure includes: first obtaining a control parameter for an autonomous vehicle; then controlling the vehicle to travel automatically under a given environment according to the control parameter, detecting and recording traveling data of the vehicle; and at last determining a dynamic parameter of the vehicle according to the traveling data. According to the method for testing dynamic parameter provided by the present disclosure, the characteristic of automatic driving of an autonomous vehicle is utilized to achieve an automatic measurement of the dynamic parameter, thereby reducing cost for calibrating the vehicle and significantly improving safety during the test. Additionally, human error caused by manually driving during the test can be avoided effectively. |
US11634146B2 |
Method and system for integrated path planning and path tracking control of autonomous vehicle
The present disclosure relates to a method and system for integrated path planning and path tracking control of an autonomous vehicle. The method includes: obtaining five input control variables and eleven system state variables of an autonomous vehicle at current time; constructing a vehicle path planning-tracking integrated state model according to the obtained variables at the current time; enveloping external contours of two autonomous vehicles using elliptical envelope curves to determine elliptical vehicle envelope curves of the two autonomous vehicles, respectively; determining time to collision (TTC) between the vehicles according to elliptical vehicle envelope curves and vehicle driving states; establishing an objective function of a model prediction controller (MPC) according to the model; and solving the objective function based on the TTC, and determining input control variables to the MPC at the next time. Autonomous vehicle collision avoidance can be achieved according to the present disclosure. |
US11634145B2 |
Systems and methods for detecting and dynamically mitigating driver fatigue
This technology relates to dynamically detecting, managing and mitigating driver fatigue in autonomous systems. For instance, interactions of a driver in a vehicle may be monitored to determine a distance or time when primary tasks associated with operation of the vehicle or secondary tasks issued by the vehicle computing were last performed. If primary tasks or secondary tasks are not performed within given distance thresholds or time limits, then one or more secondary tasks are initiated by the computing device of the vehicle. In another instance, potential driver fatigue, driver distraction or overreliance on an automated driving system is detected based on gaze direction or pattern of a driver. For example, a detected gaze direction or pattern may be compared to an expected gaze direction or pattern given the surrounding environment in a vicinity of the vehicle. |
US11634144B2 |
Sensing method and sensing device for human driven vehicles under partial VANET (vehicular ad hoc network) environment
A sensing method and a sensing device for HDVs (human driven vehicles) under a partial VANET environment are provided. According to the method, an existence sensing module and a location sensing module are constructed, based on a long-short-term-memory recurrent neural network, with utilizing historical information of motion states of a single CAV (connected and autonomous vehicle) as an input, existence and exact locations of surrounding HDVs of the CAV are outputted. The method is not only applicable to sensing the surrounding HDVs of the single CAV, but also the surrounding HDVs of the multiple CAVs. An estimation result of each CAV is firstly obtained, then the estimation results of the CAVs are checked with confliction criterion, according to checking results, the estimation results of the multiple CAVs are fused, and information about the surrounding HDVs of each CAV is finally outputted. |
US11634137B2 |
Apparatus, method, computer program, base station and vehicle for providing information related to an approaching vehicle
Embodiments relate to a method, an apparatus, a computer program, a base station and a vehicle for providing information related to an approaching vehicle. The method comprises Receiving (110) information related to a velocity of a plurality of vehicles. The method further comprises Determining (120) the information related to the approaching vehicle based on the information related to the velocity of the plurality of vehicles. The information related to the approaching vehicle indicates a presence of a vehicle of the plurality of vehicles having a velocity higher than an average velocity of the plurality of vehicles. The method further comprises Providing (130) the information related to the approaching vehicle to at least a subset of vehicles of the plurality of vehicles. |
US11634135B2 |
Driving support control device for vehicle
A device of the present disclosure controls a vehicle speed of a vehicle such that the vehicle speed matches a set vehicle speed when a preceding vehicle is not detected, and controls the vehicle speed of the vehicle such that the vehicle follows the preceding vehicle when the preceding vehicle is detected. The device controls the vehicle speed of the vehicle assuming that the preceding vehicle is not detected, when a condition that allows the vehicle to overtake the two-wheeled vehicle is satisfied and an intention of a driver to overtake a two-wheeled vehicle is detected, in a case where the two-wheeled vehicle is detected as the preceding vehicle and the vehicle speed is controlled such that the vehicle follows the two-wheeled vehicle. |
US11634132B2 |
Vehicle deceleration control system
In deceleration set processing, first-class and second-class deceleration are specified. The first-class deceleration is deceleration of the vehicle corresponding to a first-class state. The first-class state is a state of a slowdown target of the vehicle. The second-class deceleration is deceleration of a following moving body corresponding to a second-class state. The second-class state is a state of the vehicle as viewed from the following moving body. If a minimum value of the first-class deceleration (a first-class minimum value) is equal to or greater than a minimum value of the second-class deceleration (a second-class minimum value), target deceleration is set to the first-class minimum value. Otherwise, based on a second-class minimum value phase, the target deceleration is set to deceleration equal to or greater than the second-class minimum value. The second-class minimum value phase is a phase to which the second-class minimum value belongs in a second deceleration feature. |
US11634131B2 |
Method for determining a motor vehicle speed profile
A method for determining a speed profile of a motor vehicle on a route between a starting point and an arrival point. The method includes the steps of defining a series of noteworthy points of the route, which are characterized by a stoppage of the vehicle or a decrease in the speed of the vehicle, the series of noteworthy points dividing the route into a series of portions, for each portion of the route, generating a speed and/or torque setpoint optimizing the speed profile of the vehicle by minimizing the Hamiltonian of a system of equations modeling the driving of the vehicle, and providing the setpoint generated on each portion of the route so as to optimize the driving of the vehicle up to the arrival point. |
US11634129B2 |
Travel control apparatus, vehicle, travel control method, and non-transitory computer-readable storage medium
There is provided a travel control apparatus. A recognition unit recognizes a division line of a road on which a self-vehicle is traveling. A control unit executes lane maintenance control to perform lane maintenance of the self-vehicle based on a recognition result of the division line by the recognition unit. If the recognition unit has become unable to recognize the division line in a case in which a first control state for executing the lane maintenance control without issuance of a steering wheel gripping request is set, the control unit will allow preceding vehicle following control, for following a preceding vehicle of the self-vehicle, to be executed after switching the lane maintenance control to manual driving. |
US11634125B2 |
Drive assistance device and drive assistance method
In a drive assistance device, a required space estimation unit estimates a required space which is a space required for a subject vehicle to complete a starting. A required time estimation unit calculates an estimated required time which is an estimate value of a time required to complete the starting at a time of starting the subject vehicle. A collision time estimation unit calculates an estimated collision time which is an estimate value of a time until when an obstacle reaches the required space. A start margin calculation unit calculates a start margin indicating a temporal margin for the subject vehicle to complete the starting until the obstacle reaches the required space based on the estimated required time and the estimated collision time. The notification processing unit notifies a driver of the subject vehicle of the start margin. |
US11634123B2 |
Methods and systems for prioritizing computing methods for autonomous vehicles
A method includes receiving sensor data associated with one or more inputs associated with a road portion, determining a level of risk associated with each of the one or more inputs, determining an estimated amount of computing resources that each of a plurality of candidate computing methods will consume, and selecting one or more computing methods from the plurality of candidate computing methods to associate with the one or more inputs based on the levels of risk associated with the one or more inputs and the estimated amount of computing resources that the candidate computing methods will consume. |
US11634122B2 |
Method of moving autonomous vehicle after accident
A method of moving an autonomous vehicle to a safe zone after an accident is provided. The method includes: setting a threshold which is a criterion for determining a failure of a chassis system; determining whether a failure occurs by using the threshold; determining a control mode of twin clutches or a braking system; designating avoidance speed level in accordance with whether a following vehicle approaches; and setting a target trajectory to a safe zone and then generating braking torque on left and right wheels or controlling distribution of driving torque through the twin clutches in order to move the autonomous vehicle at the avoidance speed along the target trajectory. |
US11634120B2 |
Driver assistance system and driver assistance method
A driver assistance system that notifies the driver of the braking information of the preceding vehicle or improves the sensitivity of the emergency braking system if the brake lamp of the preceding vehicle is failed includes: a first sensor mounted in a vehicle, having a front field of view of the vehicle, and configured to acquire a front image data; a second sensor selected from a group consisting of a radar sensor and a lidar sensor, mounted in the vehicle, having a front field of sensing of the vehicle, and configured to acquire a front detection data; and a controller including a processor configured to process the front image data and the front detection data, and the controller is configured to: detect a velocity of the preceding vehicle travelling in front of the vehicle and a brake lamp of the preceding vehicle in response to processing the front image data and the front detection data; and determine whether the brake lamp of the preceding vehicle is failed based on the velocity of the preceding vehicle and a lighting of the brake lamp of the preceding vehicle. |
US11634118B2 |
Parking control method and parking control apparatus
A parking control method includes: performing parking control of moving a vehicle to a target parking position on the basis of an operation command acquired from an operator located outside the vehicle; when the parking control to the target parking position is suspended and the vehicle leaves the target parking position, calculating a moving direction of the vehicle on the basis of a parking direction when the vehicle is parked at a next target parking position; and moving the vehicle in the moving direction. |
US11634117B2 |
Parking support apparatus
A parking support apparatus is configured to automatically park a target vehicle in a target parking space, which is one parking space out of a plurality of parking spaces. The parking support apparatus is provided with: an acquirer configured to obtain parking information indicating a parking posture of a parked vehicle in one or a plurality of parking spaces around the target parking space, out of the plurality of parking spaces; and a determinator configured to determine a parking posture of the target parking vehicle with respect to the target parking space, on the basis of the obtained parking information. |
US11634109B2 |
Method for decelerating a vehicle, in particular a commercial vehicle, electro-pneumatic brake system for decelerating a vehicle, and vehicle having an electro-pneumatic brake system
A method is provided for decelerating a vehicle. The vehicle has an electro-pneumatic brake system, at least one front axle, at least one rear axle, and a brake value transmitter. The vehicle further includes at least one axle modulator for the front axle of the vehicle, for performing control of at least one front axle brake pressure at the at least one front axle, and/or at least one axle modulator for the rear axle of the vehicle, for performing control of a rear axle brake pressure at the at least one rear axle of the vehicle. The method includes generating a redundancy signal at a first axle, the front axle or rear axle, or at a trailer control valve, and performing open-loop and/or closed-loop control of an auxiliary brake pressure at another axle, the front axle or the rear axle, via the redundancy signal. |
US11634108B2 |
Chain cleaning device
The present invention is a chain cleaning device with a track that guides a chain through a cleaning chamber. The cleaning chamber forms air flow pathways along the sides of the chain. Discharge ports in the chamber ceiling direct a high velocity working air flow spanning the width of the chamber at the upper surfaces of the chain to generate high velocity swirling air flows that progress through the interior openings of the chain and through the pathways along the outer sides of the chain. The compact nature of the cleaning chamber and the close proximity of its walls to the chain maintain the high velocity working and swirling air flows against the various differently oriented surfaces of the chain to remove dirt, grease, grit and grime from the multi-surface chain, including the nooks and crannies where chain plates, pins and rollers come together. |
US11634105B2 |
Windshield wiper operations for aircraft
Disclosed is an aircraft having motors operable to actuate an aircraft windshield wiper and an aircraft control surface. The aircraft includes a distributed control system having digital storage and integrated with redundant processors. The aircraft includes controller instructions stored on the digital storage operable upon execution to operate a control surface motor of the motors to actuate the control surface to impact an orientation of the aircraft and operate a windshield wiper motor of the motors to actuate the windshield wipers. |
US11634104B2 |
Sensing and controlling states of locking mechanisms
An affixable device can include a locking mechanism, a force-limiting mechanism, and a sensing mechanism. The locking mechanism can include an engagement component configured to disable the locking mechanism. The force-limiting mechanism can be configured to limit a locking force of the locking mechanism. The sensing mechanism can be coupled to the engagement component, and can be configured to determine that the force-limiting mechanism has limited the locking force of the locking mechanism. In response to determining the force-limiting mechanism limiting the locking force, the sensing mechanism can cause the engagement component to disable the locking mechanism. |
US11634100B2 |
Airbag module for a curtain-type airbag
An airbag module includes a curtain-type airbag arranged in a packaged configuration, and a strap looped around the airbag. The airbag includes a mounting edge extending exteriorly along the airbag. The mounting edge includes a securement adaptor projecting therefrom exteriorly to the airbag. The strap includes two endpieces respectively anchored to the mounting edge and secured with the securement adaptor, thereby securing the strap in a loop around the airbag at the mounting edge. |
US11634099B2 |
Airbag cover
A breakable portion breaks, as a break start point portion, a portion in a vicinity of a center of a tip end side of a door portion away from a hinge portion on a rotation center side of the door portion when the door portion is opened. A breakable coupling portion in an area of the start point portion is disposed such that a width dimension between the breakable openings which are adjacent to each other in a plan view on a tip end portion away from the hinge portion is smaller than a width dimension on a base portion close to the hinge portion of the door portion. |
US11634098B1 |
Airbag supported by an armrest of a vehicle seat
An assembly includes a vehicle seat. The assembly includes an armrest supported by the vehicle seat. The armrest includes an upright portion elongated along an axis and an arm support portion supported by the upright portion. The assembly includes an airbag supported by the arm support portion of the armrest. The airbag inflatable to an inflated position. The airbag includes an upper portion extending upwardly from the arm support portion when the airbag is in the inflated position and a lower portion extending downwardly from the arm support portion when the airbag is in the inflated position. The upper portion is vehicle-inboard of the axis and the lower portion being vehicle-outboard of the axis. |
US11634095B2 |
Removable safety bar for creating a remote safety visual device
A safety system includes a vehicle and a safety device. The safety device includes a first arm and a second arm. The safety device is moveable between a first position and a second position. When the safety device is in the first position, the first arm and the second arm are coupled to the vehicle. When the safety device is in the second position, the safety device is spaced a distance away from the vehicle. |
US11634094B2 |
Methods and systems for secure communication and authorization of vehicle mode change
Electrically powered accessories connected to vehicle power systems are authenticated, and connections between the accessories and the vehicle power systems are based on permissions resulting from that authentication. accessories may supply authentication information associated with an authentication level, and form a permitted connection based on the authentication level. Vehicle power systems may obtain the authentication information, obtain the authentication level, and operate a power connection according to the authentication level. Authentication information can be obtained from the component or from a user of the component through, for example, a portable device. A system may include the electrically powered component and the vehicle power system. The system may further include a remote server to process the authentication information and determine the authentication level. |
US11634091B2 |
Acoustic fiber silencer
An acoustic fiber silencer for a motor vehicle includes a first sound absorbing layer and a second sound insulating layer. The layers are formed of lightweight fibrous material, and the sound insulating layer is quilted. The acoustic fiber silencer includes a frame to which the sound absorbing and sound insulating layers are secured. The frame provides structural support and shape to the sound absorbing and sound insulating layers. The acoustic fiber silencer is lightweight while maintaining excellent noise attenuation properties. |
US11634089B2 |
Decorative part for vehicle and method for manufacturing same
An emblem (30) (vehicle decorative part) includes a decorative main body (31) and a heater (55). The decorative main body (31) is configured to be attached to a vehicle at a front side in a transmission direction of millimeter waves from a millimeter wave radar to decorate the vehicle and has a millimeter wave transparency. The heater (55) has a heating element (57) that emits heat when energized. At least a part of the heating element (57) is located in a irradiation region (Z1) of the millimeter waves in the heater (55). As a millimeter wave attenuation reducing configuration that reduces attenuation of the millimeter waves passing through the heater (55), the heating element (57) is incorporated in the heater (55) in a condition where an area proportion of an area of a section of the heating element (57) that occupies the irradiation region (Z1) to an area of the irradiation region (Z1) is set such that an attenuation amount of the millimeter waves is less than or equal to a permissible value. |
US11634082B2 |
Ladder systems, agricultural vehicles, and related methods
A ladder system includes a fixed support, a ladder bracket supported by the fixed support, a ladder coupled to the ladder bracket and configured to rotate with respect to the ladder bracket between a lowered position and a storage position, and an air spring coupling the ladder to the ladder bracket and configured to apply a force to the ladder when the ladder is in the lowered position to keep the ladder in the lowered position. An agricultural vehicle includes a chassis supported by a plurality of wheels, and a ladder system carried by the chassis. Related methods are also disclosed. |
US11634077B2 |
Powerfold actuator for exterior mirror
A vehicular exterior rearview mirror assembly includes a mirror head pivotally mounted at a mounting arm configured for attachment at a side of a vehicle. The mirror head includes a reflective element. A powerfold actuator is operable to pivot the mirror head relative to the mounting arm between at least a folded position and a drive position. The powerfold actuator includes a primary detent that is engaged to maintain the mirror head at the drive position when the mirror head is pivoted via the powerfold actuator to the drive position. The powerfold actuator includes a secondary detent. Following pivoting via the powerfold actuator of the mirror head to the folded position, when the mirror head is manually pivoted from the folded position to the drive position, the primary detent is disengaged and the secondary detent is engaged to maintain the mirror head at the drive position. |
US11634076B2 |
Vehicular exterior mirror with actuator
A vehicular exterior rearview mirror assembly includes a mirror head movably attached at a mounting base configured for mounting at a side of a vehicle. The mirror head includes a mirror casing and a mirror reflective element. An actuator is operable to move the mirror head relative to the mounting base between at least an extended position and a folded position. The actuator includes a first detent interface that is engaged to maintain the mirror head at the folded or extended position when the mirror head is moved via the actuator to that position. The actuator includes a second detent interface that is engaged to maintain the mirror head at the folded or extended position when the mirror head is manually moved to that position. The second detent interface is not engaged while the actuator moves the mirror head between the folded position and the extended position. |
US11634075B2 |
Actuator system, rear view device, motor vehicle and adjustment method
Systems and methods are provide for an actuator system for a rear view device of a motor vehicle, configured for adjustment of a component when being connected to the actuator system The actuator system may include a drive system arranged to rotate a bayonet gear, which is coupled via at least one engagement element to a latching barrel to axially move or rotate the latching barrel along or around a rotational axis, wherein the latching barrel is configured to engage into at least one of two worm gears or to rotate the engaged worm gear when being moved or rotated. The latching barrel may be cylindrically shaped with a cylindrical surface as an engagement surface and oppositely arranged first and second sides each directed towards one of the two worm gears. |
US11634074B2 |
Image forming device and image forming method
An image acquisition unit acquires camera images obtained by cameras, which are configured to photograph a periphery of the vehicle. An image synthesizing unit projects data of the camera images on a virtual projection surface, which corresponds to the periphery of the vehicle, and forms a synthetic image showing the periphery of the vehicle, which is viewed from a virtual view point, by using the data projected on the projection surface. A travelling-environment determination unit determines whether a travelling environment of the vehicle is an off-road or an on-road based on a signal from an other on-board device of the vehicle. The image synthesizing unit is configured to change a shape of the projection surface, which is for forming the synthetic image, according to whether the travelling-environment determination unit determines that the travelling environment is an off-road. |
US11634071B2 |
Trailer sideswipe avoidance system
A trailer sideswipe avoidance system for a vehicle towing a trailer is disclosed. The trailer sideswipe avoidance system includes a sensor system configured to detect objects in an operating environment of the vehicle. The trailer sideswipe avoidance system may include a controller that processes information received from the sensor system to determine whether the object detected in the operating environment of the vehicle is in the travel path of the towed trailer. A visual display displays a trailer collision alert zone and a trailer collision avoidance zone. The position of the trailer collision avoidance zone on the visual display relative to the position of the trailer collision alert zone on the visual display directionally corresponds with a collision avoidance steering angle of the vehicle relative to a current steering angle of the vehicle when the controller determines that the object is in the travel path of the towed trailer. |
US11634063B2 |
Ultimat binder
There is provided a tensioning device for tensioning chains to secure loads on a transport vehicle. The tensioning device comprises first and second U-shaped yokes with parallel arms and an open end for coupling to fitments. The first yoke bottom has a threaded hole, while the second yoke bottom has an unthreaded hole. A threaded bolt rotatably extends through the unthreaded hole and engageably extends through the threaded hole, coupling the first and second yokes together. A limiter with a limiter leg is secured to the first yoke at the open end. The leg limits rotation of a fitment relative to the first yoke. The tensioning device includes a drive assembly having a universal type joint releasably coupleable with the threaded bolt, and an extension bar extending therefrom. Actuating the extension bar of the drive assembly rotates the threaded bolt, moving the first yoke relative to the second yoke. |
US11634062B1 |
Vehicle having divisible trunk for separately heating and cooling divided trunk compartments based on object recognition
A vehicle includes a divisible trunk defining an enclosure for storing a first object and a second object, a camera to capture first and second images of the first and second objects prior to being placed into the divisible trunk and a processor to execute a machine-vision module to process first and second image data to identify the first and second objects. The vehicle includes a trunk divider to divide the trunk into first and second trunk compartments and an actuator to displace the trunk divider from an inoperative position to an operative position. The processor outputs a divider signal to the actuator to displace the divider to divide the trunk into the first and second trunk compartments. The processor outputs a thermal control signal to a thermal controller to control first and second temperatures of the first and second trunk compartments by setting first and second setpoint temperatures. |
US11634060B2 |
Side-by-side utility vehicle
A utility vehicle includes a plurality of ground engaging members and a frame supported by the plurality of ground engaging members. The frame assembly extends generally along a longitudinal axis of the utility vehicle. The utility vehicle further includes a front seating section coupled to the frame. The front seating section is configured to support an operator and a first passenger. Additionally, the utility vehicle includes a rear seating section coupled to the frame. The rear seating section is configured to support a second passenger and a third passenger. The rear seating section has an angled panel configured as a dead pedal for the second and third passengers, and a portion of the rear seating section extends forwardly into the front seating section. |
US11634053B2 |
Angle mechanism passenger seat sleeping pillow
To ensure that passengers sleep in a good quality, comfortable and healthy sleep during their bus, airplane and train journeys and to prevent the eclipses occurring in the neck after the journey, a passenger seat sleeping pillow has an angled working principle in accordance with head and neck anatomy. The passenger seat with angle mechanism that can be produced in the system is related to the sleeping pillow and angle mechanism provides two types of assembly (FIG. 1) or (FIG. 2), optionally manual or motorized (FIG. 19), thanks to the variable apparatus enabling the assembly of the passenger seat during or after manufacturing. |
US11634052B2 |
Vehicle seat back and method of manufacturing the same
A vehicle seat back may include an integrated suspension structure including a suspension wire and suspension mounting guides coupled to both sides of the suspension wire; and a seat back pad foamed for integrating with the integrated suspension structure in a state in which the integrated suspension structure is inserted into a mold for seat back pad formation. |
US11634051B2 |
Kinetic seat assemblies for vehicles
A kinetic seat assembly that rotates based on a force applied on an occupant seated therein is provided. The kinetic seat assembly includes a primary seat cushion frame, a primary seat back frame, a secondary seat cushion frame pivotally connected to the primary seat cushion frame, and a secondary seat back frame pivotally connected to the primary seat back frame. The kinetic seat assembly further includes a front pivot mechanism for damping movement between the primary seat cushion frame and the secondary seat cushion frame in a kinetic seat vertical direction, and an upper pivot mechanism for damping movement between the primary seat back frame and the secondary seat back frame in a kinetic seat longitudinal direction. |
US11634049B2 |
Lower and upper latch anchor use detection sensing device
A child restraint seat sensing device for a vehicle including a structural element at least partially defining a volume, wherein the structural element is located in a vehicle passenger seat between a seat base and seat back or is located behind the vehicle passenger seat, a stationary anchor in the vehicle, wherein the stationary anchor is located within the volume defined by the structural element, and a sensor mounted to the structural element, wherein the sensor is configured to detect whether a child restraint seat connector is attached to the stationary anchor. |
US11634043B1 |
System and method for autonomously charging electric vehicles
An EV can be autonomously charged by using its localization and navigation capabilities. The EV determines its pose in a local area and establishes a connection with a charger coordination system. The EV requests the charger coordination system to find a charging station in the local area based on the EV's pose. The charger coordination system uses the EV's pose to find the charging station. The charger coordination system sends the location of the charging station to the EV. The EV navigates to the charger. The EV further determines its pose relative to the charging station and aligns its charge port with the charger plug of the charging station. The EV may plug itself in or request the charger coordination system to insert the charger plug into the charge port. The alignment and insertion process may be managed by using force sensors on the charger plug or charge port. |
US11634040B2 |
Vehicle connection device, ground contact unit, vehicle coupling system and method for automatically conductively connecting a vehicle contact unit with a ground contact unit
A vehicle connection device of a vehicle battery charging system has a vehicle contact unit including a base with a contacting area in which at least one first contact electrode, at least one second contact electrode and at least one third contact electrode are provided. The vehicle connection device is moveable towards the ground contact unit in a contact direction (RK) and an aligning actuator of the vehicle connection device is connected to the base in such a way that it can rotate the base about an axis of rotation that runs substantially in the contact direction (RK).Moreover, a ground contact unit, an automatic vehicle coupling system as well as a method for automatically, conductively connecting a vehicle contact unit to a ground contact unit. |
US11634035B2 |
Power source system and power source system control method
A first power source system includes a first motor control section that controls at least torque of a drive motor. When a temperature of an FC is less than or equal to a prescribed temperature Th and a demand for high output is made to the drive motor, the first motor control section limits the torque of the drive motor to be lower than a maximum torque that can be output by the drive motor, and continuously implements this torque limitation. |
US11634033B2 |
Systems and methods of vehicular braking
An electric vehicle braking system including a braking controller, a front braking system, and a rear braking system. The front braking system includes a front friction brake and a front regenerative braking system. The rear braking system includes a rear regenerative braking system and excludes a friction brake. The braking controller is configured to detect the front regenerative braking has reached a maximum force, detect additional deceleration is required, and, in response to detecting the front regenerative braking has reached the maximum force and detecting additional deceleration is required, apply the front friction brake. |
US11634032B2 |
Systems and methods for controlling a high-output DCAC inverter on a vehicle
Methods and systems are provided for controlling a high power output direct current to alternating current converter for a vehicle. In one example, a method may include at a vehicle-on event, automatically operating the converter in a first power output mode, and transitioning to a different mode of operation in response to a transition request being received at a controller of the vehicle. In this way, the different mode of operation may be subject to confirmation via an operator of the vehicle, which may improve operational performance of the direct current to alternating current converter. |
US11634028B2 |
Image processing method of generating an image based on a user viewpoint and image processing device
Provided are an image processing method and an image processing device. The image processing method includes generating an image based on viewpoint information of a user; rendering the image based on information about what is in front of the user; and outputting the rendered image using an optical element. |
US11634025B2 |
Mechanism for pivoting a charging or tank flap, an arrangement including a charging or filler neck housing, at least one charging or tank flap, and at least one such mechanism, and a vehicle having at least one such arrangement
A mechanism (1) for pivoting a charging or tank flap (2) on a charging or filler neck housing (3), which is accommodated or can be accommodated in a body component of a motor vehicle, wherein the mechanism (1) is configured, by superposing at least two at least temporarily simultaneous circular rotational movements having different rotation radii or at least one at least temporarily simultaneous circular rotational movement and at least one linear movement, to pivot the charging or tank flap (2) reversibly between a first orientation, in particular a closed position of the charging or tank flap (2), and a second orientation, in particular an open position of the charging or tank flap (2). |
US11634018B2 |
Weatherstrip
The weatherstrip includes a molded part formed from an elastic material and the molded part has an insert panel embedded therein. The molded part includes: a molded part through hole in which a clip for attaching the molded part to a vehicle body can be inserted; and a thinner portion provided in an outer peripheral portion of the molded part through hole and having a thickness smaller than that of other portions of the molded part in an area of the molded part where the insert panel is embedded in. The insert panel includes a clip through hole provided at a location corresponding to the molded part through hole and having a diameter larger than that of the molded part through hole; and a first additional through hole provided spaced from the clip through hole in an area corresponding to the thinner portion. |
US11634016B2 |
Vehicle roof
A roofing system for a Jeep type multiple row seating Jeep type SUV having a parallel separated longitudinal support beam structure extending roll cage with rear ends of the longitudinal support beams inclined to a belt line of the vehicle, the system including a rear rigid portion extending transverse of the vehicle, a cloth portion forward of the rigid portion covering at least a front seating row of the vehicle being openable. |
US11634015B1 |
Sunroof device
To provide a sunroof device with a simple structure, in which an elastic member can be disposed in a predetermined position accurately and with excellent workability, a sunroof device includes a plate-shaped panel stay having a cam groove on a first side surface and a slider provided with a cam follower pin engaging with the cam groove to cause the movable roof panel to tilt. The slider includes a slider main body having a pin support wall that supports the cam follower pin in a cantilever manner and a contact member mounted to the slider main body so as to slidably contact a second side surface of the panel stay. The contact member includes an extension part opposing a bottom surface of the panel stay, and an elastic member that elastically supports the panel stay when the movable roof panel undergoes opening and closing motion is provided on the extension part. |
US11634012B2 |
Cab for work machine and work machine
Provided is a cab for a work machine capable of preventing an actuator from being damaged by vibration. A cab body is formed with a doorway. A door is rotatably supported on the cab body. The door opens and closes the doorway. A closed position locking unit locks the door so as to disable it from rotating relative to the cab body. The actuator generates a driving force to unlock the door locked by the closed position locking unit. The actuator is mounted on the cab body and is supported by the cab body. |
US11634009B2 |
Heating system of vehicle
An indoor heating line is arranged to pass through a heater core for a coolant heater and indoor air conditioning, and is provided with a first pump so that coolant can flow. A battery heating line is branched from a downstream point of the heater core and connected to an upstream point of the coolant heater after passing through a battery heat exchange part for temperature-raising a high voltage battery, where the battery heating line includes a first heat exchange flow passage that connects a downstream point of the heater core to a first side of the battery heat exchange part, and a second heat exchange flow passage that connects a second side thereof and an upstream point of the coolant heater, where the first heat exchange flow passage and the second heat exchange flow passage are configured to mutually exchange heat. |
US11634006B2 |
Methods and apparatus for vehicle climate control using distributed sensors
Methods and apparatus for vehicle climate control using distributed sensors are disclosed. A disclosed example method includes receiving data from sensors distributed within a vehicle at a first controller, processing the data at the first controller to identify an event associated with the interior of the vehicle and sending an instruction based on the event from the first controller to a second controller of the vehicle to affect an operation of a climate control system of the vehicle. |
US11634003B2 |
Automated control system for an electronically controlled sway bar link
A sway bar system is described. The sway bar system includes a sway bar having a first end and a second end. An electronically controlled connector to provide a remotely controllable physical connection and disconnection capability between a first location on a vehicle and the first end of the sway bar; and the second end of the sway bar coupled to a second location on the vehicle. |
US11633999B2 |
Motor-vehicle with multi-mode extreme travel suspension-suspension hydraulic design
A hydraulic suspension system for a motor vehicle having at least a pair of road engaging wheels. The suspension system includes, a hydraulic cylinder coupled with the each of the pair of road engaging wheels, the hydraulic cylinder defining a cap end volume and a rod end volume separated by a piston. A hydraulic supply circuit for the hydraulic cylinder includes, a high pressure hydraulic source, a low pressure hydraulic drain, a pair of hydraulic sub circuits each coupled to one of the hydraulic cylinder cap and rod end volumes. Each hydraulic sub circuit includes, a proportional supply flow valve coupled with the high pressure hydraulic source and one of the cylinder volumes, a return flow control proportional valve coupled with the low pressure hydraulic drain and the one cylinder volume, and an accumulator coupled to the associated hydraulic cylinder volume through an accumulator fill control proportional valve. |
US11633994B2 |
Vehicle-trailer distance detection device and method
A method for determining a distance between a camera positioned on a rear portion of a tow vehicle and a trailer coupler supported by a trailer positioned behind the tow vehicle as the tow vehicle approaches the trailer. The method includes identifying the trailer coupler of the trailer within one or more images of a rearward environment of the tow vehicle. The method also includes receiving sensor data from an inertial measurement unit supported by the tow vehicle. The method includes determining a pixel-wise intensity difference between a current received image from the one or more images and a previously received image from the one or more images. The method includes determining the distance based on the identified trailer coupler, the sensor data, and the pixel-wise intensity difference, the distance includes a longitudinal distance, a lateral distance, and a vertical distance. |
US11633984B2 |
Method for preparing modified rubber, modified rubber, and bulletproof and puncture resistant tire
A method for preparing a modified rubber introduces a reactive group into a high-performance short fiber by irritating the short fiber by ultraviolet light, and modifies the short fiber by a coupling agent to increase the compatibility of the short fiber with a rubber matrix, and finally, utilizes the charge repulsion of sodium lauryl sulfate to effectively avoid the agglomeration of the short fibers in the rubber matrix, which is benefit for obtaining the modified rubber. The present disclosure further provides a modified rubber prepared by the method and a bulletproof and puncture resistant tire prepared by the modified rubber, wherein a buffer layer is made by the modified rubber, and at least one of a tread, a belt ply and an inner liner is made by the modified rubber, and a cord ply is woven by twisted high-performance long fibers. |
US11633981B2 |
Wheel hub and method for manufacturing a wheel hub
A wheel hub includes a one-piece hub base body configured to surround at least a portion of a rolling-element bearing, the base body having a first axial end region configured to attach to a wheel adapter and/or to a wheel and a second axial end region axially opposite the first axial end region. An annular reinforcing body, which may be a metal band, is mounted on a radially outer surface of the second axial end region and connected to the radially outer surface at a joint. |
US11633980B2 |
Wheel hub unit with improved drainage
A wheel hub unit provided with a radially outer ring, stationary in use, a radially inner ring, rotating in use, at least one row of rolling elements, interposed between the radially outer ring and the radially inner ring, and a sealing assembly, interposed between the radially outer ring and the radially inner ring, which defines cooperating with the radially outer ring or with the radially inner ring a shield of at least one labyrinth seal. The labyrinth seal does not have a circumferential symmetry but comprises an upper portion and a lower portion with respect to a symmetry axis (A) of the wheel hub unit and is provided with an angular interruption of the shield made on its lower portion corresponding to the lower side of the wheel hub unit so as to increase an outflow section thereof from the labyrinth seal itself which facilitates gravity drainage of contaminants present inside the sealing assembly. |
US11633976B2 |
Vehicular wheel having a spoke defining a hollow chamber and vehicles including same
A vehicular wheel assembly defines an axis of rotation and includes a wheel having an inner hub, an outer rim, and a plurality of hollow spokes. The outer rim defines an outer circumference. Each hollow spoke of the plurality of hollow spokes extends between the inner hub and the outer rim and includes a wall that at least partially defines a hollow chamber. The outer rim defines a plurality of openings that are each in fluid communication with one of the hollow chambers and each of the openings includes a tuning member. |
US11633972B2 |
Inkjet process for three-dimensional relief on tiles
A technique is described for the application of three-dimensional (3D) relief to a substrate such as a ceramic tile using digital inkjet technology. In an example embodiment, the introduced technique includes application of binder ink to a portion of the surface of a substrate using a digital inkjet process. This binder ink forms a barrier layer which protects the portion of the surface of the substrate. Next, a brushing process is applied to remove unprotected portions of the substrate, thereby forming the 3D relief in the substrate. |
US11633970B2 |
Tape support arrangement
A tape support arrangement comprises a tape take up core (220) suitable for supporting a tape; and a tape supply core (210) suitable for supporting a tape (230). The supply core (210) comprises an inner surface (212), the inner surface defining an internal volume (240) of the supply core and being configured for engagement with a tape drive support. The take up core (220) is sized and shaped such that it can be located in the internal volume (240) of the supply core (210). Refer to FIG. 2. |
US11633969B2 |
Droplet ejecting apparatus and droplet ejecting method in which relative positions of workpiece table and droplet ejecting head are corrected
A control unit obtains a captured image of a reference workpiece by a second image capturing unit after a droplet ejected from a droplet ejecting head lands toward a reference mark formed on an upper surface of the reference workpiece, detects a positional deviation amount of a position of the reference mark and a landing position of the droplet based on the captured image, and calculates the correction amounts of the relative positions of a workpiece table and a droplet ejecting head based on the positional deviation amount. |
US11633967B2 |
Base material processing apparatus and base material processing method
A base material processing apparatus includes a tension detector that detects tension on a base material that is being transported, an encoder that detects the amounts of rotational drive of rollers that transport the base material, edge position detectors that detect the position of an edge of the base material in the width direction, and a transport displacement calculation part that calculates a transport displacement of the base material in the transport direction. The transport displacement calculation part includes an operation unit that has completed learning through machine learning and outputs the transport displacement on the basis of at least one of the result of detecting the tension, the result of detecting the amounts of rotational drive of the rollers, and the result of detecting the position of the edge. Accordingly, the transport displacement can be detected with high accuracy and low cost. |
US11633965B2 |
Printer
A printer includes a first accommodating portion, a supply roller, a recording device, a cutter configured to cut a recording medium into a first recording medium and a second recording medium, a second accommodating portion, a third accommodating portion that accommodates an unrecorded second recording medium that is the second recording medium on which an image has not been recorded by the recording device, and a switcher. The third accommodating portion is movable between a first position at which the third accommodating portion receives the unrecorded second recording medium cut by the cutter and a second position at which the unrecorded second recording medium accommodated in the third accommodating portion is in contact with the supply roller. The supply roller is configured to supply the unrecorded second recording medium accommodated in the third accommodating portion that is positioned at the second position. |
US11633964B2 |
Intermediate unit, post processing device, and printing apparatus
An intermediate unit includes a transportation path provided with a drying unit that accelerates the drying of the medium. The transportation path includes an inlet path, an outlet path, a first branch path, a second branch path, a first junction path, a second junction path, a switch-back type inversion path with a first inversion path and a second inversion path. The first branch path and the second branch path which branch off at a branch point from the inlet path. The first junction path and the second junction path and the outlet path join each other at a junction point. The first branch path and the first junction path and the first inversion path join each other at a first connection point. The second branch path and the second junction path and the second inversion path join each other at a second connection point. |
US11633962B2 |
Printing device
Provided is a printing device in which a height position of an object can be accurately adjusted with a simple configuration. The printing device includes: a base part having an opening on a side and multiple first slits and second slits disposed side by side in an up-down direction; a support member for supporting the object, slidably engaged with any first and second slit among the first and second slits in a lateral direction from the opening side and being slidable through the opening between a pull-out position pulled out from the base part and a storage position stored in the base part; and a head part disposed above the support member at the storage position and ejecting ink toward the object supported by the support member. |
US11633957B2 |
Recording method and recording apparatus
A recording method for using a line-type recording apparatus to scan a recording medium with a plurality of line heads once for recording, the line heads having a width greater than or equal to the recording width of the recording medium, the method including a treatment liquid deposition step of depositing a treatment liquid containing a coagulant on the recording medium, and an ink deposition step of ejecting a coloring ink composition from the line heads to deposit the coloring ink composition on the recording medium, wherein in the ink deposition step an identical coloring ink composition is ejected from a first line head placed on the upstream side in the transport direction perpendicular to the width direction of the recording medium and from a second line head placed on the downstream side in the transport direction. |
US11633956B2 |
Liquid discharge head, liquid discharge device, liquid discharge apparatus, and intermediate member
A liquid discharge head includes a liquid port, a frame including a liquid channel in which a liquid supplied from the liquid port flows, and an intermediate member between the liquid port and the frame. The liquid port includes a first connection portion connectable to the frame, the frame includes a second connection portion connectable to the first connection portion of the liquid port, and the intermediate member includes a third connection portion connectable to the second connection portion of the frame and a fourth connection portion connectable to the first connection portion of the liquid port. |
US11633953B2 |
Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head includes head chips configured to eject a liquid toward a medium in a first-direction, in which, when a width direction of the medium is a second-direction, a direction orthogonal to the first-direction and the second-direction is a third-direction, and a direction perpendicular to the first-direction and intersecting the second-direction and the third-direction is a fourth-direction, the head chips include a first-chip group in which first head-chips are arranged side by side in the second-direction, the first-head chip having a first-nozzle row formed by arranging first-nozzles side by side in the fourth-direction, and a second-chip group in which second-head chips are arranged side by side in the second-direction, the second-head chip having a second-nozzle row formed by arranging second-nozzles side by side in the fourth-direction, and the first-chip group is arranged side by side in the third-direction with respect to the second-chip group. |
US11633950B2 |
Image forming apparatus, droplet discharge control method, and storage medium
An image forming apparatus includes: a piezoelectric element with a common electrode on one side and an individual electrode on another side; a nozzle; and circuitry. The circuitry selects one from drive signals and supplies the one drive signal to the piezoelectric element via the individual electrode, to discharge a droplet through the nozzle to form an image. Each drive signal includes waveform pulses including a main pulse that rises in a slope shape during a rising time and finishes rising at an end time. The circuitry generates the drive signals so that the end time of a less influential drive signal other than a most influential drive signal falls within a range of the rising time of the main pulse of the most influential drive signal; selects the one drive signal based on an image to be formed; and supplies the one drive signal to the piezoelectric element. |
US11633947B2 |
Automated system and method for forming a laminated structure
A method of removing a backing layer from a panel, made of an uncured pre-impregnated fiber-reinforced polymer, comprises a step of orienting the panel into a backing-separation orientation relative to an edge-engagement tool. The method also comprises a step of positioning the panel into a backing-separation position relative to the edge-engagement tool. The method further comprises a step of moving the edge-engagement tool, when the panel is in the backing-separation orientation and the backing-separation position, so that backing-engagement features of the edge-engagement tool engage the backing layer, at only an edge portion of the backing layer, and just the edge portion of the backing layer separates from the panel. The method additionally comprises a step of gripping the edge portion of the backing layer, and, when gripped, moving the backing layer relative to the panel so that an entirety of the backing layer separates from the panel. |
US11633939B2 |
Method for producing a planar composite component and composite component produced thereby
A method for producing a planar composite component having a core layer (B), which is arranged between and integrally bonded to two cover layers (A, A′), wherein the cover layers contain a cover-layer thermoplastic and wherein the core layer contains a core-layer thermoplastic, comprises the following steps: a) a heated stack with layer sequence A-B-A′ is provided; b) the heated stack (A-B-A′) is pressed; c) the pressed stack is cooled, whereby the planar composite component with consolidated layers integrally bonded to each other is formed. To improve the production method including the producibility of planar 3D components, it is proposed, that at least one of the cover layers (A, A′) in unconsolidated form comprises a fibrous nonwoven layer of 10 to 100 wt.-% thermoplastic fibers of the cover-layer thermo-plastic and 0 to 90 wt.-% of reinforcing fibers having an areal weight of 300 to 3,000 g/m2; the core layer (B) in unconsolidated form comprises at least one randomly-oriented-fiber nonwoven layer (D) formed from reinforcing fibers and thermoplastic fibers of the core-layer thermoplastic, and that after the pressing the consolidated core layer(s) has/have an air pore content of <5 vol.-% and the consolidated core layer has an air pore content of 20 to 80 vol-%. |
US11633937B2 |
Skin foam-in-place foamed article and production method thereof
There is provided a skin foam-in-place foamed article comprising a pad (15) and a bag-like outer material (20) covering the pad (15). The outer material (20) has a top layer (21) and a liner layer (22) made of a foamed resin. The liner layer (22) has a closed cell structure. A pad-side skin layer (27a) having a density higher than that of a bulk layer (26) is provided on the liner layer (22), on a side of the pad (15). A corona treatment is applied to the pad-side skin layer (27a). |
US11633935B2 |
Humidity and sag resistant building panel
Described herein is an stain and sag resistant acoustic building panel comprising a porous body formed from building material and latex binder, wherein the building material may include fibers and filler and at one of the building materials has been pre-treated with a charge-modifying component, thereby enhancing the sag-resistance of the building panel. |
US11633929B2 |
Bead-apex storage system and method for handling a plurality of stacks with bead-apexes and spacers
Disclosed is a bead-apex storage system and a method for handling carriers, each carrier supporting a stack of bead-apexes stacked in a stacking direction and alternated with spacers separating the bead-apexes, wherein the bead-apex storage system includes a plurality of storage stations for storing the carriers and a transfer station for transferring one of the plurality of bead-apexes to a tire building machine, wherein the bead-apex storage system further includes a spacer gripper for lifting one or more of the spacers from one of the carriers in one of the plurality of storage stations and for carrying said one or more lifted spacers to the transfer station, wherein the bead-apex storage system includes a spacer gripper base for supporting the spacer gripper, wherein the spacer gripper base is movable from the transfer station to any one of the plurality of storage stations. |
US11633925B2 |
System and method for improving thermoset-thermoplastic interface adhesion
Illustrative examples of forming and using suitably adapted materials for improving interface strength between thermoset-thermoplastic joined parts includes exposure of a thermoplastic substrate to a plasma to form an amine-functionalized substrate having amine chemical moieties disposed on a first surface. The first surface of the thermoplastic substrate is positioned adjacent to and contacts a second surface of a thermoset substrate to form a workpiece. The thermoset substrate includes epoxide chemical moieties on and within material forming the thermoset substrate. The workpiece is subsequently heated to form a structure, where heating of the workpiece causes covalent chemical bonds to form between the plasma-treated first surface of the thermoplastic substrate and the second surface of the thermoset substrate. Thereafter, additional thermoplastic components can be fusion bonded to a surface of the thermoplastic substrate opposite the first surface—thereby providing improved attachment of additional thermoplastic components to the thermoset substrate. |
US11633924B2 |
Cycloolefin polymer bonding method
A cycloolefin polymer (COP) bonding method wherein a first material that is COP and a second material that is COP or glass are bonded. The method includes: a step of exposing at least a bonding surface of the first material to H2O plasma; and a step of mating the bonding surface of the first material and a bonding surface of the second material. According to the method, the cycloolefin polymer (COP) can be bonded to a target material without applying high pressure or high temperature, and without affecting the optical properties. |
US11633921B2 |
Near-field microwave heating system and method
A microwave heating device includes a variable frequency microwave power supply, a waveguide launcher, and a fixture to contain a material to be heated, with the fixture located directly adjacent to the end of the launcher. All heating occurs in the near-field region. This condition may be insured by keeping the thickness of the fixture or workpiece under one wavelength (at all microwave frequencies being used). The launcher is preferably a horn or waveguide configured to apply the microwave power to a small area to perform spot curing or repair operations involving adhesives and composites. The spot curing may secure components in place for further handling, after which a thermal or oven treatment will cure the remaining adhesive to develop adequate strength for service. A related method is also disclosed. |
US11633916B2 |
Very high temperature hot end for fused deposition modeling printer
A fused deposition modeling printer comprises a head assembly comprising a heating head. The heating head has a top, a bottom, and a conduit extending between the top and the bottom, wherein the surface of the conduit is adapted to guide a flow of material therein. The heating head comprises an electrically conductive layer along the conduit surface that, when powered, generates heat heating the flow of material traveling in the conduit. One realization uses top and bottom electrical contacts. One realization uses several circumferential electrical contacts to power the heating head. |
US11633911B2 |
3D printing method and apparatus
A printing apparatus is for printing a three-dimensional object. The apparatus includes an operative surface, an energy source for emitting at least one energy beam onto the operative surface and a powder dispensing mechanism for depositing powder onto the operative surface, the powder being adapted to be melted by the or each energy beam. The powder dispensing mechanism is configured to deposit multiple layers of powder onto the operative surface simultaneously. |
US11633910B2 |
Resin solidification substrate and assembly
A solidification substrate assembly for making a three-dimensional object from a solidifiable material includes a solidification substrate assembly. In certain examples, the solidifiable material solidifies in contact with the solidification substrate, and the tilting of the substrate and/or or the use of a peeling member facilitates separation of the substrate from the solidified material. In other examples, the solidification substrate assembly includes a film that is adjacent to a rigid or semi-rigid layer. The solidifiable material solidifies in contact with the film, and a peeling member peels the film away from the solidified material. Intelligent solidification substrate assemblies are also described in which a force sensor determines when to expose the solidifiable material to solidification energy and/or whether to use a peeling member to separate the solidification substrate from a solidified objection section. |
US11633909B2 |
Methods, systems, and devices for three-dimensional object generation and physical mask curing
Systems, apparatus, and methods are described for additive manufacturing or three dimensional (3D) printing of objects using a set of physical masks. An additive manufacturing device can include one or more light sources, a vessel containing a volume of print material and a transparent base through which light can enter the vessel to cure a portion of the volume of print material, and a set of masks defining a series of patterns associated with layers of a 3D object that are each positionable between the light source and the transparent base to control a pattern of the light that is received through the transparent base and therefore the pattern of the cured portion of print material. |
US11633908B2 |
Latent cure resins and related methods
The present disclosure relates generally to curable resins, in particular latent cure resins, and related methods for use in an additive fabrication (e.g., 3-dimensional printing) device. |
US11633906B2 |
Expansion apparatus, shaping system, and manufacturing method of shaped object
An expansion apparatus includes: a first expander for irradiating with electromagnetic waves emitted from a lamp a thermal conversion layer for conversion of the electromagnetic waves to heat, to cause at least a portion of a thermal expansion layer to expand, the thermal conversion layer being laminated to a molding sheet including a base and the thermal expansion layer laminated to a first main surface of the base; and a second expander for causing expansion of a region (C) of the thermal expansion layer that is smaller in size than a region (B) of the thermal expansion layer expanded by the first expander. |
US11633904B2 |
Long plastic layer with embossing in register with pattern and rolling method and device therefor
A long plastic layer with an embossing in register with a pattern, a rolling method and a device are described herein. The method comprises a feeding step of feeding a plastic layer into oppositely rolling rollers; and a rolling step of hot rolling an embossing on the plastic layer. A feeding tension of the plastic layer is adjusted according to a longitudinal deviation between the embossing and the pattern in the rolling step. The device comprises a first feeding device, an oppositely rolling rollers control device, a detecting device, and a tension controller disposed on the first feeding device. According to the long plastic layer with the embossing in register with the pattern manufactured by the method, the embossing on the plastic layer is in register with the pattern on the plastic layer. The present invention provides the method, the device and the long plastic layer with the embossing in register with the pattern processed using the method, implementing the embossing rolled on the plastic layer in register with the pattern on the plastic layer and having high production efficiency, low cost and less energy consumption. |
US11633900B2 |
Device for handling preforms for heating units
The invention concerns a device for handling preforms for heating units. The device includes a mandrel that defines a rotation axis of the preforms; a tip mounted at an end of the mandrel and having a part penetrating into the neck of the preforms; a rubbing contact rigidly connected to the tip; and a heatsink rigidly connected to the mandrel and intended to come into contact with the tip. The tip also includes a cooling part axially in line with the penetrating part. The cooling part includes at least one thermal exchange raised portion in contact with the surrounding air. Furthermore, the tip is mounted such that it can be mobile on the mandrel. |
US11633897B2 |
Method, device and injection molding machine for manufacturing clamping ring
Disclosed are a method, an extruder and an injection molding machine for manufacturing a clamping ring, solving problems that products produced by an extrusion method needs to be processed in two steps. The key point of technical solutions lie in a molding step of acting on a pipe member in a plastic melt state via a molding die set, to form a clamping ring from the pipe member; an injection mold injects plastic materials having memory properties through an injection gate to form a pipe member in the molding cavity, the pipe member comprises a clamping ring and a sealing film provided on one end of the clamping ring, the hydraulic mechanism drives a molding cutter to cut out a joint of the sealing film and the clamping ring in a plastic melt state, thereby a limit end is formed at one end of the clamping ring. |
US11633888B2 |
Method for manufacturing a tableware article having a thermal-transfer printed pattern
A method for manufacturing a tableware article having a thermal-transfer printed pattern includes the following steps. Firstly, a PET resin composition including 3 to 15% by weight of an inorganic filler is provided. Next, the PET resin composition is granulated to obtain plastic granules. Then, the plastic granules are molded into the tableware article and the tableware article is post-crystallized. Finally, a thermal transfer printed pattern is printed on a surface of the post-crystallized tableware article. |
US11633884B2 |
Method of manufacturing a layer
A method of manufacturing a separate and continuous layer being essentially uncured. The method includes applying a powder mix including fibres and a thermosetting binder on a carrier, forming a powder mix layer, wherein the powder mix is connected together such that the powder mix layer is obtained and wherein the powder mix layer is essentially uncured, and releasing the powder mix layer from the carrier. Also, a layer and a method for manufacturing a building panel. |
US11633879B2 |
Anatomic tissue-engineered osteochondral implant and method for fabrication thereof
A method for forming a prosthesis comprising a bone-like portion and a cartilage-like portion can comprise additively manufacturing a first positive mold in accordance with a portion of a first three-dimensional model of a portion of a bone. A first negative mold can be formed from the first positive mold. The bone-like portion can be created within the first negative mold. A second positive mold of the bone and a cartilage can be additively manufactured from a second three-dimensional model. A portion of the second three-dimensional model can correspond to a portion of the first three-dimensional model. A second negative mold can be formed from the second positive mold. The bone-like portion can be positioned in the second negative mold so that the second negative mold and the bone-like portion can define a cartilage space that can be filled with a material to form the cartilage-like portion of the prosthesis. |
US11633876B2 |
Slurry scraping mechanism and applying and scraping device used in SG abrasive production process
A slurry scraping mechanism and an applying and scraping device used in an SG abrasive production process includes a scraping master support; a scraper, wherein the scraper is connected with the scraping master support through a suspension component such that the scraper is suspended, and a damping spring is arranged in the suspension component; and a torsion spring adjusting component, wherein the torsion spring adjusting component includes a plurality of torsion springs supported by a torsion spring support shaft, the torsion spring support shaft is fixed to the scraping master support, the torsion spring support shaft is movable up and down relative to the scraping master support, the torsion springs are clamped in a V-shaped plate, an end side of the V-shaped plate is connected with the scraping master support, and a side surface of the V-shaped plate is connected with the scraper. |
US11633872B2 |
Processing apparatus
A processing apparatus includes a chuck table, a first and second image capturing units, a display device, and a controller. The first image capturing unit obtains a first image group of images captured of a processed groove in the workpiece at different positions along a thicknesswise direction, each including a piece of first image information representing a shape of the processed groove. The second image capturing unit obtains a second image group of images captured of the processed groove at different positions along the thicknesswise direction of the workpiece, each including a piece of second image information representing a shape of the processed groove. The controller orders the pieces of at least either the first or the second image information into a sequence along the thicknesswise direction, thereby generating a three-dimensional image of the processed groove, and displays the three-dimensional image on the display device. |
US11633865B2 |
Mechanically actuated end of arm tooling device
A mechanical device for grasping an object includes a lower arm defining a proximal end portion, a distal end portion, an inner profile, and at least one track disposed along a portion of the lower arm between the proximal end portion and the distal end portion. An upper arm is pivotally connected to the lower arm, the upper arm defining a proximal end portion, a distal end portion, and an inner profile. An actuator is pivotally connected to the proximal end portion of the upper arm, the actuator including at least one protrusion slidably disposed within the track of the lower arm. |
US11633863B2 |
Condition-based robot audio techniques
Methods, systems, and apparatus, including computer programs encoded on computer storage media, for audio augmentation of physical robot sounds. A robot can determine that a first physically moveable component of the robot is to be actuated and in response, obtain a conditional state of the robot. The robot can obtain an audio object that generates an audio enhancement for the first physically moveable component being actuated, the audio enhancement having one or more characteristics that match the obtained conditional state of the robot. The robot can output the audio enhancement while actuating the first physically moveable component. |
US11633862B2 |
Automatic control method of mechanical arm and automatic control system
An automatic control method of a mechanical arm and an automatic control system are provided. The automatic control method includes the following steps: obtaining a color image and depth information corresponding to the color image through a depth camera; performing image space cutting processing and image rotation processing according to the color image and the depth information to generate a plurality of depth images; inputting the depth images into an environmental image recognition module such that the environmental image recognition module outputs a displacement coordinate parameter; and outputting the displacement coordinate parameter to a mechanical arm control module such that the mechanical arm control module controls the mechanical arm to move according to the displacement coordinate parameter. |
US11633858B2 |
Method and system for simulating a braking operation of a robot
A method for simulating a braking operation of a robot wherein a dynamic model of the robot is used to determine, for a given initial state of the robot, a final state range with a plurality of possible final states of the robot as a result of the simulated braking operation. |
US11633856B2 |
Spatiotemporal controller for controlling robot operation
A robot may include a spatiotemporal controller for controlling the kinematics or movements of the robot via continuous and/or granular adjustments to the actuators that perform the physical operations of the robot. The spatiotemporal controller may continuously and/or granularly adjust the actuators to align completion or execution of different objectives or waypoints from a spatiotemporal plan within time intervals allotted for each objective by the spatiotemporal plan. The spatiotemporal controller may also continuously and/or granularly adjust the actuators to workaround unexpected conflicts that may arise during the execution of an objective and delays that result from a workaround while still completing the objective within the allotted time interval. By completing objectives within the allotted time intervals, the spatiotemporal controller may ensure that conflicts do not arise as the robots simultaneously operate in the site using some of the same shared resource. |
US11633853B2 |
Dynamic manipulator strength augmentation
Systems (100) and methods (900) for controlling movement of an articulating arm having a plurality of joints. The methods comprise: receiving, by the controller, a command to perform a task by the articulating arm; ranking movements of the joints based on how much each said joint needs to move at a first time in order to follow the command; selecting a first subset of joints with top-ranked movements from the plurality of joints, where the subset of joints comprises less than a total number of joints contained in the plurality of joints; and causing only the joints of the first subset to move during a first timeslot of a plurality of timeslots. |
US11633852B2 |
Computing device, machine learning method, and storage medium
A computing device performs computation for controlling operations of a mobile manipulator configured to hold a plurality of target objects with a manipulator and move the target objects to predetermined positions. The computing device includes a storage and a calculator. The storage stores a trained machine learning model trained by inputting a plurality of training data sets, which are combinations of state variables and pieces of determination data associated with the state variables. The training data sets are acquired in advance. The calculator outputs a movement-target object to be moved to a predetermined position at current time by inputting the state variable to the trained machine learning model read from the storage. The state variable contains relative positions of the target objects to a specific portion of the mobile manipulator. The determination data associated with the state variable represents the movement-target object. |
US11633851B2 |
Control method for robot system
A robot system includes a robot arm driven by an electric motor and a vehicle that is movable and supports the robot arm. A control method includes (a) moving the vehicle to a work station of a first type and (b) driving the robot arm in the work station of the first type. The (a) executes a first operation mode for, in a part of the movement to the work station of the first type, moving the vehicle in a state in which electric power is not supplied to the electric motor, starting supply of the electric power to the electric motor during the movement of the vehicle in the state in which the electric power is not supplied to the electric motor, and arranging the vehicle in the work station of the first type in a state in which the electric power is supplied to the electric motor. |
US11633849B2 |
Soft robotic device with fluid emission for burrowing and cleaning
A soft robot includes a main body configured as a tube inverted back inside itself to define a pressure channel, such that when the channel is pressurized, the main body everts, and inverted material everts and passes out of a tip at a distal end of the main body. A fluidization tube for passing air or other fluid through a core of the main body in the fluidization tube, wherein the fluidization tube engages the main body such that the fluidization tube is ejected as the distal end as the main body everts and joins part of the side of the main body as the main body everts and extends its distal tip. |
US11633846B2 |
Ergonomic attachment for a ninety degree drill assembly
A removable attachment assembly for a ninety degree drill assembly, which includes a base member and a securement assembly secured to the base member for releasably securing the base member to a housing of the ninety degree drill assembly. The removable attachment assembly further includes a cushion member releasably securable to the base member. |
US11633842B2 |
Gas spring-powered fastener driver
A gas spring-powered fastener driver includes a cylinder, a moveable piston, a driver blade attached to the piston, the driver blade movable with the piston, a lifter including a rotary component operably coupled to the driver blade to move the driver blade from a driven position to a ready position, and a multi-stage planetary transmission. The transmission includes an output shaft operatively coupled to the lifter to provide torque thereto, a first bearing supporting a first portion of the output shaft for rotation, a second bearing supporting a second portion of the output shaft for rotation. The fastener driver also includes a housing having a cylinder support portion in which the cylinder is received and a transmission housing portion in which the first and second bearings are received to rotatably support the output shaft. The cylinder support portion and the transmission housing portion are integrally formed as a single piece. |
US11633837B2 |
Retrofittable auxiliary pliers handle assembly
A retrofittable auxiliary pliers handle assembly includes a coupler removably coupled to a grip of a pair of pliers. The coupler is positionable between a free end of the grip and a pivot of the pliers. The coupler includes a receiver positioned laterally away from an exterior lateral surface of the grip. An auxiliary handle is positioned in the receiver such that the auxiliary handle is positioned adjacent to the exterior lateral surface and extends away from the pivot. A finger space is defined between the auxiliary handle and the grip. The auxiliary handle comprises a plate that elongated and has a first end, a second end, a first lateral side, a second lateral side, an upper edge and a lower edge. The coupler engages the plate adjacent to the first end such that the first lateral side faces the exterior lateral surface. |
US11633831B2 |
Grinding head for floor grinding machine comprising at least one belt pulley, floor grinding machines and methods
The present disclosure relates to a grinding head for a floor grinding machine for grinding floor surfaces of stone or stone-like material. Such a grinding head comprises a lower casing member, comprising a lower support and an upwardly extending edge portion, and an upper casing member, comprising an upper cover and a downwardly extending edge portion, wherein the upper casing member is joinable to the lower casing member by causing axially distal portions of the edge portions to bear on each other. |
US11633828B2 |
Substrate polishing system, substrate polishing method and substrate polishing apparatus
A first and a second substrate polishing apparatus and are provided with a film thickness sensor for measuring a film thickness of layer to be polished and polish the layer by pressing the substrate against a polishing pad. The first substrate polishing apparatus outputs difference between output value of the film thickness sensor when an underlayer is exposed and output value of the film thickness sensor when the substrate is not present, as a first offset value. The second substrate polishing apparatus has a storage unit that stores information of the first offset value, an output correction unit that corrects the output value from the film thickness sensor based on the first offset value, and an end point detection unit that outputs control signal indicating end point of substrate polishing when measured value of the film thickness of the layer calculated based on the corrected output value reaches target value. |
US11633827B2 |
Device for processing optical workpieces, particularly spectacle lenses
A device for processing spectacle lenses has a work chamber, which is accessible by way of an opening and in which a workpiece mount and at least one tool mount are opposite one another and movable relative to one another so that a processing region of a tool held at the tool mount can be brought into processing engagement with a workpiece held at the workpiece mount and in processing engagement can be guided over the workpiece. For recognition of wear at the tool, a sensor equipment with at least one contactlessly operating sensor arrangement is provided and is movable outside the work chamber between a protected rest position and a detecting position. In the detecting position the sensor equipment is constructed to detect at the processing region of the tool held at the tool mount an unacceptable deviation beyond a predetermined amount from a desired geometry. |
US11633817B2 |
Manufacturing system
A manufacturing system manufactures a rotating assembly by attaching a plurality of attached target members in a circumferential direction of a rotating main body portion. A storage member capable of storing the plurality of attached target members is placed on a stand. A measurement device measures a physical amount of the attached target member An attachment device attaches one attached target member to a predetermined position in the circumferential direction of the rotating main body portion based on the physical amount measured by the measurement device A transfer device transfers the attached target member. |
US11633813B2 |
Real-time weld quality analysis systems and methods
A weld system includes: a robot control module configured to actuate a robot and move a welder along a joint of metal workpieces during welding, the welder being attached to the robot; a weld control module configured to, during the welding, apply power to the welder, supply a shield gas, and supply electrode material; a vision sensor configured to, during the welding, optically measure distances between the vision sensor and locations, respectively, on an outer surface of a weld bead created along the joint by the welder; and a weld module configured to: determine a strength of the weld bead at a location based on: the distances at the location along the joint; and at least one parameter from at least one of the robot control module during the welding, the weld control module during the welding, and a sensor configured to capture data of the welding during the welding. |
US11633809B2 |
Grain-oriented silicon steel having heat-resistant magnetic domain and manufacturing method thereof
A heat-resistant magnetic domain refined grain-oriented silicon steel, a single-sided surface or a double-sided surface of which has several parallel grooves which are formed in a grooving manner, each groove extends in the width direction of the heat-resistant magnetic domain refined grain-oriented silicon steel, and the several parallel grooves are uniformly distributed along the rolling direction of the heat-resistant magnetic domain refined grain-oriented silicon steel. Each groove which extends in the width direction of the heat-resistant magnetic domain refined grain-oriented silicon steel is formed by splicing several sub-grooves which extend in the width direction of the heat-resistant magnetic domain refined grain-oriented silicon steel. The manufacturing method for a heat-resistant magnetic domain refined grain-oriented silicon steel comprises the step of: forming grooves on a single-sided surface or a double-sided surface of a heat-resistant magnetic domain refined grain-oriented silicon steel in a laser grooving manner, a laser beam of the laser grooving is divided into several sub-beams by a beam splitter, and the several sub-beams form the several sub-grooves which are spliced into the same groove. |
US11633808B2 |
Silicon steel product with low iron loss for low-noise transformer, and manufacturing method thereof
An oriented silicon steel product with a low iron loss for a low-noise transformer, and manufacturing method thereof are provided. The oriented silicon steel product comprises: a silicon steel substrate, a magnesium silicate bottom layer formed on a surface of the silicon steel substrate, and an insulation coating applied on the magnesium silicate bottom layer. The magnesium silicate bottom layer has a visible light normal reflectivity (R) of 40-60% for. By strictly controlling the visible light normal reflectivity of the magnesium silicate bottom layer of the silicon steel substrate and the evenness of the gloss of magnesium silicate bottom layer, lower iron loss, and reduced magnetostriction can be achieved, and thus a silicon steel product with low noise and particularly suitable for transformers can be obtained. |
US11633804B2 |
Laser processing apparatus and laser processing method
A laser processing apparatus includes: a chuck table for holding a single-crystal SiC ingot on a holding surface thereof; a laser beam applying unit for applying a laser beam to the single-crystal SiC ingot held on the holding surface of the chuck table; and a camera unit configured to capture an image of the single-crystal SiC ingot held on the holding surface of the chuck table. The chuck table includes a porous material making up the holding surface and a glass frame made of a non-porous material and having a recess defined therein and receiving the porous material fitted therein, and a negative pressure transfer path for transferring a negative pressure to the porous material fitted in the recess. |
US11633802B2 |
Method for operating double-action friction stir welding device, and double-action friction stir welding device
A method for operating a double-action friction stir welding device including a welding tool having a pin member and a shoulder member, a projection/retraction mechanism for causing the pin member to project/retract relative to the shoulder member, a rotation mechanism for rotating a welding tool, and an advancing/retracting mechanism for advancing/retracting the welding tool, the method including cleaning at least one of the outer circumferential surface of the pin member and the inner circumferential surface of a through hole of the shoulder member on the basis of the level of an adhesion parameter correlated with the degree of adhesion of the material of a welding object, caused by friction stir welding, on the outer circumferential surface of the pin member and the inner circumferential surface of the through hole of the shoulder member. |
US11633800B2 |
Method for contactlessly striking an arc and welding current source for carrying out a striking process
The invention relates to a method for contactless ignition an arc (L) between an electrode (3) and a workpiece (4) which is to be welded, for carrying out a welding process, wherein a welding current (I) and a welding voltage (U) are provided at an output (2) of a welding current source (1), wherein the welding current source (1) contains a resonance converter (5) for generating a periodically varying, preferably substantially sawtooth-shaped, open circuit welding voltage (ULL) with voltage maxima (ULL,max) which recur periodically with a repetition rate (fw) and a welding current source (1) for carrying out the igniting process. In order to achieve reliable contactless ignition of the arc (L) without complicated circuitry, the resonance converter (5) is formed by a series-parallel resonant converter, and temporally synchronous high-frequency pulses (UI,HF) are superimposed on the open circuit welding voltage (ULL) in the region of at least some of the periodically recurring voltage maxima (ULL,max) of the open circuit welding voltage (ULL). |
US11633795B2 |
Tabletop cutting machine
An easily operable, highly durable cutting machine finely adjusts the miter angle of a turntable. A cutting machine includes a turntable supported in a manner rotatable horizontally to a base and including a substantially disk-shaped table body to receive a workpiece and a table extension protruding forward from the table body, a cutting machine body located above the turntable and connected in a manner swingable vertically to the turntable, and a fine angle adjuster that adjusts a rotation angle of the turntable with respect to the base and including a rack on the base, a pinion located in the table body within an area of the table body as viewed from above and engageable with the rack directly or indirectly, and an operation part operable to rotate the pinion. |
US11633790B2 |
Method for rapid development of additive manufacturing parameter set
An apparatus includes a control system that defines a test part having multiple features of multiple feature types. The control system controls an additive manufacturing (AM) machine to print multiple copies of the test part, with each copy being printed according to a respective set of values used as printing parameters. A measurement system obtains a computed tomography (CT) image of each of the copies of the test part. An analysis system, for each of the plurality of feature types, analyzes the CT images to identify a selected set of values for the printing parameters. The analysis system identifies a portion of the CT image related to a first feature and assesses its density based on an average grayscale value. The AM machine is then controlled to print production parts according to, for each feature type of the production parts, the selected set of values for the printing parameters. |
US11633789B2 |
Compliant heat exchangers, heat pipes and methods for making same
A method for fabricating heat exchangers using additive manufacturing technologies. Additive manufacturing enables the manufacture of heat exchangers with complex geometries and/or with internal and external integral surface features. Additive manufacture also facilitates the manufacture of heat exchangers with regional variations, such as changes in size, shape and surface features. In one embodiment, the present invention provides a heat exchanger with a helicoidal shape that provides axial elastic compliance. In one embodiment, the internal channel of the heat exchanger varies along its length. The internal channel may have a cross-sectional area that increases progressively from one end to the other. In one embodiment, the external shape of the tubular structure may be non-circular to optimize heat transfer with an external heat transfer fluid. In one embodiment, the present invention provides a heat pipe with an internal wicking structure formed as an integral part of the additive manufacturing process. |
US11633788B2 |
Cleaning of a 3D printed article
The present disclosure relates to a method and apparatus for cleaning a 3D printed article, in particular a 3D printed heat exchanger. After 3D printing, an article may have internal passages formed from bonded powder and said passages may contain unbonded powder that needs to be removed before further use of/processing of the article. To remove this unbonded powder, the article is filled with a cleaning fluid and vibrated. The cleaning fluid is then pumped out of the article and past a sensor that generates a magnetic field. The sensor detects the presence of powder particles in the fluid by detecting a perturbation of the magnetic field caused by said particles. The fluid is then filtered and returned to a reservoir for use. The sensor may indicate the article is sufficiently clean when a detected concentration of particles in the fluid drops below a threshold. |
US11633779B2 |
Method and apparatus for manufacturing a forged component
A method for manufacturing a forged component includes: performing hot forging on a material; heating the hot forged material to a first set temperature; and performing warm coining to correctly shape the heated material. The material may be heated to a second set temperature before hot forging. The material heated to the second set temperature may be hot forged. The second set temperature may be higher than the first set temperature. The hot forged material may be subjected to controlled cooling to a third set temperature at a predetermined cooling rate. The controlled cooled material may be heated to the first set temperature. The third set temperature may be lower than or equal to the first set temperature. |
US11633777B2 |
Manufacturing methods for wheel rim, spoke and steel wheel and steel wheel formed by methods
Some embodiments of the present disclosure provide manufacturing methods for a wheel rim, a spoke and a steel wheel and a steel wheel formed by the methods. The methods includes that: a wheel rim/a spoke blank is heated in a heating furnace, and the heated wheel rim/the heated spoke blank is transferred onto a hot press. A temperature of the wheel rim/the spoke blank being required to be kept above a required temperature in a process of transferring the heated wheel rim/the heated spoke blank to the hot press. Then the wheel rim/the spoke blank is formed in the hot press. A formed wheel rim and a formed spoke are connected to product a steel wheel. |
US11633775B2 |
PEX expansion tool
An expansion tool includes a housing, a motor supported within the housing, a mandrel, and a drive mechanism configured to convert a rotational input from the motor into translational movement of the mandrel. The drive mechanism includes a cam and a drive shaft coupled to the cam. The expansion tool further includes a frame including a hub and a neck extending from the hub and having an opening. A working element is coupled to the neck and has a plurality of jaws movable from a closed position toward an expanded position in response to movement of the mandrel from a retracted position toward an extended position. The mandrel extends through the opening to engage the jaws, and the drive shaft is rotatably supported by the hub. |
US11633774B2 |
Machined article and pressing method
A machined article 100 includes a first member 101 including an inner peripheral portion 101a formed by a hole, and a second member including an outer peripheral portion 102a fitted into the inner peripheral portion 101a of the first member 101. At least either an inner peripheral recess 101b to be formed in part of the inner peripheral portion 101a of the first member 101 or an outer peripheral recess 102b to be formed in part of the outer peripheral portion 102a of the second member 102 is formed. A slit 103 penetrating from a front to a back is formed at a position to which the inner peripheral recess 101b or the outer peripheral recess 102b corresponds, between the first member 101 and the second member 102. |
US11633769B2 |
Chassis for small electronic device and method for forming same, and rolled aluminum alloy laminated sheet material for chassis for small electronic device
To provide a chassis for a small electronic device that can be formed efficiently by drawing work with low cost, is hard to cause forming failure, and causes no damage on the surface thereof on forming to provide an excellent appearance. The rolled aluminum alloy laminated sheet material is for forming a chassis for a small electronic device by drawing work, and contains a rolled aluminum alloy sheet material having a 0.2% proof stress of 200 MPa or more, and a covering material laminated at least one surface of both surfaces of the rolled aluminum alloy sheet material, and the covering material contains any one of a synthetic resin film, and a laminated material containing a metal foil having synthetic resin films laminated on both surfaces thereof. The rolled aluminum alloy sheet material may have a fibrous crystalline structure extending in a direction perpendicular to a thickness direction thereof. |
US11633767B2 |
Systems and methods for recovering landfill gas
A landfill gas recovery system includes a waste layer disposed in a landfill and a capping layer overlying the waste layer. The capping layer includes a cured sealing layer and a loose fill layer between the waste layer and the cured sealing layer. The loose fill layer includes a granular fill material. The cured sealing layer includes a composite of the granular fill material and a cured water soluble polymer. The cured sealing layer is substantially impermeable to landfill gases formed within the waste layer. |
US11633766B2 |
Cleaning apparatus, system and method
The disclosure is directed to an apparatus, system and method for cleaning interior surfaces of storage containers such as tank trailers and other surfaces using a low volume of high pressure fluid. The apparatus of this disclosure includes one or more high pressure fluid conduits that can be extended and retracted within a storage container. |
US11633764B2 |
Cleaning apparatus with anti-hair wrap management systems
A cleaning apparatus includes an end cap assembly for use with an agitator. The end cap assembly includes a stationary end cap, a rotating end cap, and a fragmentor. The stationary end cap is secured to and stationary with respect to a housing of the cleaning apparatus. The rotating end cap is coupled to the agitator and rotates with the agitator relative to the housing. The stationary and rotating end caps define a gap extending radially inward therebetween. The fragmentor is disposed within the gap and is configured to break debris which enters the gap into smaller pieces. The fragmentor may be disposed on a surface of the stationary end cap facing towards the rotating end cap and/or on a surface of the rotating end cap facing towards the stationary end cap. The fragmentor may include a cutting blade and/or an abrasive surface. |
US11633763B2 |
Sequential imaging for container sidewall inspection
A container inspection system is described herein. The container inspection system includes a camera and a computing system, wherein the camera is configured to capture multiple images of a transparent container as the transparent container is transported along a conveyor. Thus, the camera captures several images of the transparent container when the transparent container is at different positions relative to the camera. The container inspection system detects a defect in the transparent container based upon one or more images in the several images. |
US11633762B2 |
Adjustable roll sizer
An adjustable roll sizer for sorting objects of different sizes includes a first set of rollers mounted to a support structure and arranged in a first parallel array. A second set of rollers is mounted to the support structure in a second parallel array that is interleaveably alignable with the first parallel array. Means for automatic control are provided for misaligning the second parallel array from the first parallel array to vary gap width between adjacent rollers. Each roller in the second parallel array may also be tapered to vary gap width as a function of roller length. Rollers may include helical ridges for urging objects along the gaps. |
US11633761B2 |
Driving apparatus, vibration generating apparatus, electronic apparatus, and driving method
Provided is a driving apparatus that sets a signal wave in a low-frequency region having a frequency of 10 Hz or more and 250 Hz or less as a modulating wave and outputs to a piezoelectric actuator a driving signal having a waveform obtained by modulating an amplitude of a sine wave in a high-frequency region having a frequency of 20 kHz or more and 40 kHz or less with the modulating wave. |
US11633760B2 |
Multilayer coating film formation method
The multilayer coating film formation method for forming a multilayer coating film on a substrate comprises the steps of: applying an undercoat paint composition (X) comprising an antioxidant (a1) to a substrate to form at least one layer of an uncured first coating film; applying a topcoat paint composition (Y) containing a carboxy-containing polymer (b1) and an epoxy-containing acrylic resin (b2) to the first coating film to form an uncured second coating film; and simultaneously heating the uncured first coating film and the uncured second coating film to cure the films. |
US11633757B2 |
Apparatus and methods for use in applying a fluid to a surface
A fluid applicator for use in a fluid application system includes a base plate comprising at least one rail and a housing slidably coupled to the base plate. The fluid applicator also includes a plurality of fluid permeable pads positioned within the housing and a fluid delivery conduit coupled to the base plate and to the housing. The fluid applicator further includes an actuator configured to selectively move the housing and the plurality of pads along the rails between a first position and a second position. The plurality of fluid permeable pads are in flow communication with the fluid delivery conduit in the first position, and the plurality of fluid permeable pads are prevented from being in flow communication with the fluid delivery conduit in the second position. |
US11633754B2 |
Fragrance atomization and diffusion device convenient for replacing a fragrance liquid container
The present application relates to a fragrance atomization and diffusion device convenient for replacing a fragrance liquid container. The fragrance atomization and diffusion device convenient for replacing a fragrance liquid container comprises a housing, an atomization mechanism, a bottom cover and a top cover respectively located at two ends of the housing and enclosing a chamber, a bracket fixedly mounted within the chamber, a gas supply assembly and a power supply assembly, the atomization mechanism, the gas supply assembly and the power supply assembly each mounted at the bracket; the bracket is provided along the vertical direction with a mount cavity for mounting the atomization mechanism, an end of which extends through the top cover; and the atomization mechanism comprises an atomization head and a liquid storage bottle connected to the atomization head. The present application has the advantage of convenient addition of a fragrance liquid. |
US11633751B2 |
Release agent spraying device and forming apparatus
A release agent spraying device that sprays a release agent to a die of a forming apparatus main body, the release agent spraying device includes a motor, a moving nozzle that advances and retreats in a direction intersecting a moving direction of the die and jets the release agent from a tip, and a connection mechanism that connects the motor to the moving nozzle and advances and retreats the moving nozzle by a rotation output of the motor in one direction. |
US11633748B2 |
Fluid cartridge for a plural component sprayer
A fluid cartridge for a plural component sprayer is configured to receive first and second component materials and purge air from the sprayer and provide the first and second component materials and purge air to a mix chamber for spraying. The fluid cartridge includes a cartridge body, material flowpaths extending from a second end to a cartridge bore, and a purge path extending from the second end to the cartridge bore. Fluid checks are disposed in the material flowpaths and purge path to prevent backflow out of the fluid cartridge. Side seals are disposed in the material paths and are pre-loaded to extend into the cartridge bore and engage a mix chamber within the cartridge bore. |
US11633747B2 |
Head for dispensing fluid material
A fluid dispenser head (T) including a spray wall (26) that is perforated with a network of holes (O) through which the fluid under pressure passes so as to be sprayed in small droplets;the dispenser head being characterized in that the network of holes (O) comprises at least two series of holes (O), with the holes (O) of a given series presenting holes that are substantially identical in size, and with the holes (O) of different series presenting holes that are different in size, such that one series of holes (O) generates a spray of small droplets with droplet sizes that define a first Gaussian distribution, while another series of holes (O) generates a spray of small droplets with droplet sizes that define a second Gaussian distribution that is offset relative to the first Gaussian distribution, thus producing a complex spray having at least two distinct Gaussian distributions. |
US11633745B2 |
Polymerized metal catalyst air cleaner
A method of making an electronic air filter that requires obtaining a first metallic plate comprising copper and a second metallic plate comprising copper. The method also requires creating a first pattern of slits through the first metallic plate's thickness and a second pattern of slits through the second metallic plate's thickness and expanding (a) the first slitted metallic plate to form a first aperture metallic plate and (b) the second slitted metallic plate to form a second aperture metallic plate wherein when the first aperture metallic plate and the second aperture metallic plate are properly aligned and positioned in an electronic air cleaner device then the apertures in the first aperture metallic plate and the apertures in the second aperture metallic plate misalign or do not align with each other. Another requirement is that the method calls for applying a dielectric conducting and antimicrobial agent polymer material to (a) the first aperture metallic plates to form a first coated, aperture metallic plate and (b) the second aperture metallic plates to form a second coated, aperture metallic plate. |
US11633744B2 |
Magnetic Ljungstrom filter
A heat exchange apparatus for removing magnetic particulates from a gas stream, including a rotating element basket having a regenerative heat exchanger and at least one magnetic element. A method of removing magnetic particulates from a gas stream, including heating the regenerative heat exchanger during a first portion of a cycle as a segment of the rotating element basket passes through a first zone wherein contact is made with a flue gas thereby accumulating any magnetic particulates as they are attached to the magnetic element. Then cleaning a portion of the magnetic element during a second portion of the cycle. And cooling the regenerative heat exchanger and simultaneously heating an inlet air stream during a third portion of the cycle as the segment of the rotating element basket passes through a third zone wherein fluidic contact is made with the air inlet stream. |
US11633741B2 |
Slide chamber
The invention is directed to a slide chamber comprising a top member (10), a fluidic seal (20), a transparent closure member (30) and base member (40) wherein the top member (10) is provided with at least one examination chamber (11) and a plurality of openings (12) positioned at two sides of the cover member outside of the examination chamber (11); and the base member (40) is provided with interconnecting means (41) complementary to the openings (12) of the top member characterized in that the interconnecting means (41) of the base member (40) and the openings (12) of the top member (10) are configured to mechanically interlock with each other by lateral movement thereby pressing the top member (10) against the transparent closure (30) member in a water-tight manner. |
US11633740B2 |
Reagent vessel for storing a liquid reagent
A reagent vessel, an apparatus and a method for manufacturing a lower part of a reagent vessel for an analytical instrument are disclosed. The reagent vessel is configured to store a liquid reagent. The reagent vessel comprises a cover and a lower part. The lower part comprises a bottom wall, a front wall, a rear wall, two opposing side walls and at least one connection wall. The cover, bottom wall, front wall, rear wall and two opposing side walls define at least one internal volume for storing at least one liquid reagent. The two opposing side walls are at least partially connected to one another by the at least one connection wall located within the at least one internal volume. The connection wall is spaced apart from the bottom wall. The connection wall and at least the two opposing side walls can be injection-molded and are monolithically formed. |
US11633739B2 |
Droplet-based assay system
System for performing a flow-based assay. The system may comprise a droplet generator to produce an emulsion including droplets in a carrier fluid. The system also may comprise a thermocycler including two or more temperature-controlled zones and also including a channel connected to the droplet generator for receiving the emulsion. The channel may form a single-pass continuous fluid route traversing the temperature-controlled zones multiple times, such that droplets passing through the channel are thermally cycled. The system further may comprise a detection station downstream from the thermocycler and configured to detect a signal from the droplets after such droplets have been thermally cycled by passing through the channel. |
US11633738B2 |
Devices and methods for sample analysis
Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. |
US11633735B2 |
Hybrid modular thin film microfluidic microwave sensing apparatus, systems, and methods
A sensor and method for use in measuring a physical characteristic of a fluid in a microfluidic system is provided. A microfluidic chip has a thin deformable membrane that separates a microfluidic channel from a microwave resonator sensor. The membrane is deformable in response to loading from interaction of the membrane with the fluid. Loading may be fluid pressure in the channel, or shear stress or surface stress resulting from interaction of the membrane with the fluid. The deformation of the membrane changes the permittivity in the region proximate the sensor. A change in permittivity causes a change in the electrical parameters of the sensor, thereby allowing for a characteristic of the fluid, such as flow rate, or a biological or chemical characteristic, to be measured. Also, a microwave sensor with improved sensitivity for characterizing a fluid in a microfluidic channel is provided. The sensor has a rigid and very thin layer, for example in the range of 10 um to 100 um, in the microfluidic chip allowing for the positioning of the sensor very close to the microfluidic channel, which enables very high resolution sensing. |
US11633734B2 |
Device for synthesizing oligonucleotides
The invention relates to a device for synthesising oligonucleotides, comprising: a reagent container receptacle (1) for holding a reagent container support (17) comprising multiple reagent containers (18); an exchangeable microfluid chip (10) comprising a synthesis chamber, fluid connectors and microfluid valves; a control device (5); fluid connecting means (2); wherein the device can be loaded with the microfluid chip (10) and the reagent container support (17) when in a loading position; a chip receptacle (3). To allow cost-effective and prompt synthesis even of small amounts of oligonucleotides, the invention provides for an actuator device (6) to be provided, with which the reagent container receptacle (1), the microfluid chip (10) and the fluid connecting means (2) can be brought from the loading position to an operating position, in which operating position the reagent container receptacle (1), the chip receptacle (3) and the fluid connecting means (2) are positioned relative to each other such that reagents can be conveyed out of the reagent containers (18) towards the synthesis chamber (14) depending on the valve position of the microfluid valves. |
US11633725B2 |
Composite material, its manufacturing, generation and use in methane cracking
Here disclosed is a composite catalyst for methane cracking and a method of producing the composite catalyst. The composite catalyst includes a substrate formed of metal oxide, and one or more catalytic transition metals solubilized in the metal oxide, wherein the metal oxide includes a metal which differs from the one or more catalytic transition metals, wherein the metal oxide forms a matrix which the one or more catalytic transition metals are solubilized in to render transition metal ions from the one or more catalytic transition metals, wherein the transition metal ions under a reducing atmosphere diffuse to reside as transition metal nanoparticles at a surface of the substrate and the transition metal nanoparticles under an oxidizing atmosphere diffuse away from the surface to reside as transition metal ions in the metal oxide, and wherein the transition metal nanoparticles at the surface induce carbon from the methane cracking to deposit on the transition metal nanoparticles and have the carbon deposited grow away from the substrate. |
US11633722B2 |
Catalyst for water splitting
Methods for producing a carbon-free, PGM-free support for PGM catalyst. The catalytic material comprises PGM metals disposed on a carbon-free support which is catalytic but free of PGM. |
US11633720B2 |
Super absorbent polymer and method for producing same
The super absorbent polymer comprises: a base polymer powder including a first crosslinked polymer of a water-soluble ethylenically unsaturated monomer having at least partially neutralized acidic groups; and a surface crosslinked layer formed on the base polymer powder and including a second crosslinked polymer in which the first crosslinked polymer is further crosslinked via a surface crosslinking agent, wherein the super absorbent polymer has: a fixed height absorption (FHA) of 22.5 g/g to 29 g/g, a saline flow conductivity (SFC) of 35 (·10−7 cm3·s/g) or more, and T-20 of 180 seconds or less. |
US11633719B2 |
Superabsorbent polymer composition and method for preparing the same
The present invention relates to superabsorbent polymer and a method for preparing the same. The present invention can provide a superabsorbent polymer in which a hydrophobic material having an HLB of 0-6 and a surface cross-linking agent are mixed into a base resin prepared in the presence of water dispersible silica, thereby having improved rewetting characteristics and permeability through surface-modification of the base resin. |
US11633718B2 |
Removal of bacteria from drinking water via filtration
The present invention relates to a method for producing biocidal, porous particles of a cross-linked polymer, and to the porous particles that can be produced according to the method of the invention. The invention further relates to porous particles of an amino-group-containing polymer (polyamine) having a relatively low swelling factor. The porous particles according to the invention are used to remove biological contaminants from water and to bind metal-containing ions from solutions. The present invention further relates to a filter cartridge which contains the porous cross-linked polymer particles according to the invention. |
US11633717B2 |
Measurement method for properties of particulate absorbent agent, and particulate absorbent agent
Provided are a water-absorbing resin having more excellent balance of fluid retention capacity, liquid permeability, and low dustiness and a novel measurement method which enables evaluation of excellent physical properties of the water-absorbing resin. A method for measuring an absorption speed of a particulate water-absorbing agent is a method including the step of applying pressure to a portion of a bottom surface of a measurement container (51) by use of a flat plate (52) in a state in which part or whole of the particulate water-absorbing agent (56) is fixed on the bottom surface of the measurement container (51), the bottom surface being surrounded by a frame, introducing an aqueous solution through a liquid injection inlet (54) with which the flat plate (52) is equipped, and then measuring the amount of time elapsed until an end of absorption of the introduced aqueous solution by the particulate water-absorbing agent (56). |
US11633716B2 |
Immunosuppressive protein adsorption material and adsorption column
An objective of the present disclosure is to provide an adsorption material that has a carrier material with retained physical strength, and efficiently adsorbs an immunosuppressive protein. The present disclosure provides an adsorption material for immunosuppressive protein. The adsorption material includes a water-insoluble carrier to which at least one nitrogen-containing compound selected from a polyamine represented by a predetermined formula and aliphatic amines represented by predetermined formulae is bound. A total content of amino groups on the water-insoluble carrier is more than 0 μmol and 2500 μmol or less per 1 g, and a content of primary amino groups on the water-insoluble carrier is 450 μmol or less per 1 g. |
US11633714B2 |
Preparation method for combined modified straw active particulate carbon adsorption material and use of same
A preparation method for a combined modified straw active particulate carbon adsorption material and use of same. The preparation method for the combined modified straw active particulate carbon adsorption material comprises the following steps: 1) mixing straw powders, distilled water, a binder and a composite mineral, then pelletizing same, and then placing same in a tube furnace for pyrolysis to prepare straw particulate carbon; 2) introducing an inert gas into a modification reagent, adjusting the pH value combined and 3) soaking the straw particulate carbon into the combined modification solution for 30 min, and performing cleaning and drying, so as to obtain a combined modified straw active particulate carbon adsorption material. The combined modified straw active particulate carbon has a good adsorption effect on phosphate group in low-pollution water. |
US11633713B2 |
Ultra-high performance and high purify biogenic silica filtration media
This disclosure relates to ultra-high performance diatomite products possessing very high silica specific volume, a characteristic which provides for high filtration performance, in terms of low unit consumption and long filtration cycle times. These novel products of this disclosure also show very low extractable metals for both the non-acid washed and the high purity (acid washed) grades. These characteristics are of particular value in the separation of solids from high purity liquids in electronic chemical, specialty beverage and life science applications. In addition to outstanding physical and chemical characteristics, these products also contain no detectable levels of cristobalite and have a wide range of permeabilities, and are produced from mineralogically impure ores containing high levels of alumina and iron oxide. |
US11633711B2 |
Preparation method of La(OH)3 nanorod coated walnut shell biochar composite
The present invention relates to a preparation method of La(OH)3 nanorod/walnut shell biochar composite material (LN-WB), comprising the following steps: putting walnut shell powder into a crucible and pyrolyzing and carbonizing in a muffle furnace at 350° C. to 450° C.; after the pyrolysis is completed, grinding and sieving the obtained biochar, and then repeatedly washing with deionized water; drying the washed biochar for later use; putting an appropriate amount of biochar into the deionized water to form a turbid solution; simultaneously dropwise adding LaCl3 and NaOH to the above turbid solution by using a peristaltic pump; and allowing the obtained mixture to stand at room temperature for 20 to 30 h, washing and drying for later use. The present invention successfully prepares a La(OH)3 nanoparticle-loaded biochar composite material through a simple synthesis technology. |
US11633709B2 |
Treatment apparatus
In order to provide a treatment apparatus that can efficiently perform microwave irradiation, a treatment apparatus includes: a vessel made of a microwave-reflecting material, and having a first end and an irradiation opening portion, which is an emitting portion of microwaves that are emitted into the vessel; a first filter located so as to partition the vessel, and configured to separate solids that are to be separated, from the contents of the vessel; and a first reflecting member located closer to the first end than the emitting portion is and so as to partition the vessel, and configured to allow at least the contents having passed through the first filter to pass through the first reflecting member, and to reflect microwaves. |
US11633707B2 |
Bi-modal radial flow reactor
A bi-modal radial flow reactor comprising a cylindrical outer housing surrounding at least five cylindrical, concentric zones, including at least three annulus vapor zones and at least two catalyst zones. The at least two catalyst zones comprise an outer catalyst zone and an inner catalyst zone. The at least three annulus vapor zones comprise an outer annulus vapor zone, a middle annulus vapor zone, and a central annulus vapor zone, wherein the central annulus vapor zone extends along a centerline of the bi-modal radial flow reactor. The outer catalyst zone is intercalated with the outer annulus vapor zone and the middle annulus vapor zone, and the inner catalyst zone is intercalated with the middle annulus vapor zone and the central annulus vapor zone. A removable head cover can be fixably coupled to a top of the cylindrical outer housing to seal a top of the bi-modal radial flow reactor. |
US11633706B2 |
Dispenser for viscous materials
The present invention relates to a dispenser for viscous materials that includes a static mixer, a first and second receptacle R1 and R2 for a first and second viscous material, connected in fluid communication with the static mixer, a first and second actuator configured for discharge of receptacle R1 and R2, an electrically or manually operable drive and a mechanical or hydraulic power transmission configured to translate drive motion into first and second actuator motion. |
US11633703B2 |
Insert assembly for foaming device
An insert assembly for a foam generating device includes a first insert and a second insert with a channel defined therethrough. Inserts may be formed by two shell halves that are coupleable to one another to define the channel. A plurality of ribs extends along an interior surface of the channel. Pad structures defined by porous media are provided in the channel and gripped by the plurality of ribs. The pads receive cleaning solution passing through the channel and cause foam to be generated by breaking-up the cleaning solution and agitating. The ribs may be arranged horizontally relative to a longitudinal axis of the insert assembly and retain the pads within the device. Inserts may be arranged in series along a longitudinal axis of the foam generating device with the pad structures arranged within the channel. |
US11633697B2 |
Disposable device for filtering a large medium volume
A single-use device for filtration of a large volume of medium including a plurality of single-use filter units, at least some of which, preferably all of which, are connected to each other by rigid pipes. The filter units include at least one prefilter and at least one main filter for virus filtration which is configured as a hollow fiber capsule. |
US11633693B2 |
Filtration in gas dehydration
A filter for a sorbent regeneration process includes a base, a central rod, support frames, and a filter screen. The central rod is coupled to the base and defines a longitudinal axis of the filter. Each of the support frames are coupled to and protrude radially from the central rod. Each of the support frames are coupled to the base. For each pair of neighboring support frames, the filter includes a triangular support member disposed between the pair of neighboring support frames. Each triangular member is coupled to the central rod and to each of the neighboring support frames. The filter screen surrounds the support frames and is coupled to the support frames and to the base. |
US11633692B2 |
Absorbent liquid for CO2 and/or H2S, and apparatus and method using same
An absorbent liquid which absorbs at least one of CO2 and H2S from a gas, including a secondary linear monoamine; a tertiary linear monoamine or a sterically hindered primary monoamine; and a secondary cyclic diamine, wherein a concentration of each of the secondary linear monoamine, the tertiary linear monoamine or the sterically hindered primary monoamine; and the secondary cyclic diamine is less than 30% by weight. |
US11633684B2 |
Interlock for genuine filter recognition
Various example embodiments relate to a filtration system and methods for the installation and use of such a filtration system. According to a set of embodiments, the filtration system comprises a housing that defines a central compartment therein. The filtration system further comprises a filter cartridge positioned within the central compartment of the housing. The filter cartridge comprises a filter media and an identification element. The filtration system further comprises a sensor. The sensor is structured to sense the identification element of the filter cartridge. The filtration system further comprises a filter blocking mechanism communicably coupled to the sensor. The filter blocking mechanism is structured prevent installation of the filter cartridge into the housing unless filter cartridge information of the identification element sensed by the sensor is identified as corresponding to an authorized filter cartridge. |
US11633677B2 |
Static coalescer, system and method therefor
A coalescence method and related system are disclosed herein. A multiphase dispersion feed comprising first and second liquids (i.e. where droplets of the first liquid (dispersed phase) are dispersed in the second liquid (continuous phase)) is passed through a static mechanical droplet-coalescer comprising a channel characterized by a plurality of in-series segments, each segment characterized by a segment-specific-characteristic obstacle size and having geometric features disclosed herein. In embodiments of the invention, the static mechanical droplet-coalescer promotes coalescence between droplets of first liquid to form larger droplets of first liquid. Subsequently, after the dispersion exits the coalescer, the larger droplets are easier to remove from the second liquid (continuous phase) than the smaller droplets that coalesced into the larger droplets. |
US11633675B2 |
Apparatus and method for a drill mud plant
A remediation plant for remediating drilling mud, cuttings, and fluids. The preferred plant includes a reboiler that is adapted to provide heat to the drilling mud, cuttings, and fluid, a mud drum that is operatively connected to the reboiler, a distillation column that is operatively connected to the reboiler, a heat exchanger that is operatively connected to the reboiler, a condenser that is operatively connected to the distillation column, a condenser tank that is operatively connected to the condenser, an oil-water separator that is operatively connected to the condenser tank, and a pump that is operatively connected to the oil-water separator. The preferred remediation plant is adapted to remove synthetic drilling fluid from drilling mud, cuttings, and fluids. A method for remediating drilling mud, cuttings, and fluid. |
US11633673B2 |
Modular amusement park systems and methods
A system in accordance with present embodiments includes an amusement park system having one or more hardware components and a controller. The controller includes a memory device having a game layer and a software layer stored thereon. The game layer includes game logic, and the software layer includes a game API communicatively coupled to the game layer, a wrapper API communicatively coupled to the game API, and multiple wrappers communicatively coupled to the wrapper API. The controller further includes a processor configured to execute instructions to cause the processor to receive a signal indicative of a change in the hardware components, and, based on the signal indicative of the change in the hardware components, communicate with the hardware components via a wrapper to receive an input from the hardware components, or drive operation of the hardware components. |
US11633667B2 |
Augmented reality system and method of operation thereof
A system and method of operation of an augmented reality system includes: a position sensor (140) for calculating a current location (144); an orientation sensor (142), coupled to the position sensor (140), for calculating a current orientation (146); and a control mechanism (118), coupled to the position sensor (140), for presenting a system object (126) based on the current location (144), the current orientation (146), an object location (128), an object orientation (130), an access right (120), a visibility (134), and a persistence (136). |
US11633661B2 |
Video rebroadcasting with multiplexed communications and display via smart mirrors, and smart weight integration
A method includes causing display, during a first time period and via a first set of multiple smart mirrors, of live video depicting at least one user associated with the first set of multiple smart mirrors, without displaying a workout video. The method also includes causing display, during a second time period following and mutually exclusive of the first time period, and via a second set of multiple smart mirrors, of a workout video and a representation of at least one user associated with the second set of smart mirrors. The method also includes causing display, during a third time period following and mutually exclusive of the second time period, and via a third set of multiple smart mirrors, of live video depicting at least one user associated with the third set of multiple smart mirrors. |
US11633660B2 |
Video rebroadcasting with multiplexed communications and display via smart mirrors, and smart weight integration
A method includes causing display, during a first time period and via a first set of multiple smart mirrors, of live video depicting at least one user associated with the first set of multiple smart mirrors, without displaying a workout video. The method also includes causing display, during a second time period following and mutually exclusive of the first time period, and via a second set of multiple smart mirrors, of a workout video and a representation of at least one user associated with the second set of smart mirrors. The method also includes causing display, during a third time period following and mutually exclusive of the second time period, and via a third set of multiple smart mirrors, of live video depicting at least one user associated with the third set of multiple smart mirrors. |
US11633658B2 |
Weightlifting barbell roller and systems and methods for using the same
Systems and methods for reducing injury sustained during weightlifting and for making deadlifting more comfortable by encouraging correct form with reduced risk of injury. Specifically, this disclosure relates to systems and methods for reducing injury during a deadlift by providing a cushioned, free-spinning roller protective device on an associated barbell which roller is configured to roll relative to the barbell so that contact between the roller and the users leg results in the barbell bar rolling along the leg. |
US11633656B2 |
System and method for a golf putting training aid apparatus
Various embodiments for a golf putting training aid having a first stake coupled to a second stake by an upper alignment string and a lower alignment string that collectively establish parallel reference putting lines when the first and second stakes are deployed around a putting surface to train a golfer to properly align their eyes when executing a putt are disclosed. |
US11633655B1 |
Swing aid
A swing aid is provided, comprising: a support member, having an elongated shape with a first end and a second end; a first assembly, comprising a first shell and a second shell, the first shell and the second shell being pivotally connected to the first end, the first shell and the second shell being rotatable around the first end to adjust included angles with respect to the support member, respectively; a second assembly, comprising a first indicator and a second indicator, and the first indicator and the second indicator being pivotally connected to the second end, the first indicator and the second indicator being rotatable around the second end to adjust the included angles with respect to the support member, respectively. |
US11633654B2 |
Putting exerciser for evaluating hitting speed and tempo of putter
An exerciser includes: sensor installation units provided to be spaced apart from and face each other in a direction parallel; a radiation unit for radiating light, in a first sensor installation unit; a light receiving unit for receiving the light radiated from the radiation unit, in a second sensor installation unit; a speed detection unit for detecting a speed of the golf ball by checking a moment the golf ball passes; a position measurement unit for measuring a position of the golf ball; an operation control unit for performing calculation to detect an initial position value of the golf ball and a moving speed Vb and a moving distance Hb of the golf ball; and a storage unit for storing the measured speed Vb and distance Hb of the golf ball. |
US11633647B2 |
Selectively adjustable resistance assemblies and methods of use for exercise machines
The present invention relates to selectively adjustable speed and incline levels for treadmills. An example treadmill includes a platform around which a belt rotates, a drive motor for controlling a speed of rotation of the belt, a linear motor for controlling an incline of the platform, a human machine interface configured to receive from a user a first selection regarding at least one of the speed of rotation of the belt and the incline of the platform, at least one manual lever configured to receive from the user a second selection to respectively refine the first selection, and at least one controller that selectively changes the speed of rotation of the belt or the incline of the platform based on the first selection received by the human machine interface, and selectively and respectively refines the first selection based on the second selection received by the at least one manual lever. |
US11633644B2 |
Dynamic neck muscle exerciser
The present invention may be embodied as a system or method for dynamically exercising a user's neck muscles. The system includes a headset, an arm attached thereto, a weight, and at least one motor to move the weight, for example, about the arm. The weight may be mounted eccentrically on a radial track that is rotatable by one motor and moved linearly by another motor. The direction of the arm, the distance between an apex of the headset and the weight, the eccentricity of the weight on the axis, and the speed of rotation of the motor are all parameters that can be adjusted by the caregiver or user, either manually or via controlling software. |
US11633643B2 |
Methods of assembling exercise apparatus
A rowing exercise apparatus has a linkage assembly that is provided in two boxes. One box includes a forward frame member, a crank rotatably mounted on the forward frame member, and a forward portion of a seat supporting link operatively connected to the crank. Another box includes a rearward frame member, a rocker link pivotally mounted on the rearward frame member, and a rearward portion of the seat supporting link operatively connected to the rocker link. The linkage assembly is made suitable for use by rigidly connecting the two frame members to one another and by rigidly connecting the two portions of the seat supporting link to one another. At least one bracket is rigidly interconnected between the two portions of the seat supporting link. One such bracket is welded onto a rearward end of the forward portion of the seat supporting link to underlie and directly support a proximate end of the rearward portion of the seat supporting link. A seat is mounted on the seat supporting link for movement through at least one elliptical path as the linkage assembly moves through cycles relative to the rigidly interconnected frame members. |
US11633638B2 |
Fire hose reeling system
A fire hose reeling system includes a support frame that is positionable on a ground surface. The support frame has a first lateral edge and a second lateral edge. A reel apparatus is mounted on the support frame. The reel apparatus releasably engages a fire hose and forms the hose into a roll when the reel apparatus is actuated. A stabilizing panel has a perimeter edge pivotally coupled to the support frame such that the stabilizing panel is positionable in an upright position defining a stored position or in deployed position extending away from the first lateral edge. When in the deployed position, the stabilizing panel abuts the ground surface and is stepped upon while the reel apparatus is used to stabilize the assembly. |
US11633635B2 |
Inflatable fire barrier
A fire barrier includes an inflatable base deployable from an empty state to a fully inflated state and a first row of panels including a plurality of first panels disposed on the inflatable base. The base supports the plurality of first panels in an upright state when the inflatable base is in the fully inflated state, thereby forming a wall having a front side and a rear side opposing the front side. Each of the plurality of panels is independently elastically bendable with respect to the inflatable base. A coating of an infrared reflective material is disposed on each of the plurality of panels on the front side of the wall. |
US11633626B2 |
Methods for real-time image guided radiation therapy
Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images. |
US11633625B2 |
Radiation therapy system and method
The present disclosure relates to a therapeutic apparatus including an MRI apparatus configured to acquire MRI data with respect to a region of interest. The MRI apparatus may include a plurality of main magnetic field coils coaxially arranged along an axis. The MRI apparatus may also include a plurality of shielding coils arranged coaxially along the axis. A current within at least one of the shielding coils may be in the same direction with a current within the main magnetic field coils. |
US11633622B2 |
Bactericidal methods and compositions
Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects. |
US11633621B2 |
System and method for automated personalized brain modulation with photobiomodulation
A novel photobiomodulation (PBM) system and method that comprehensively directs therapeutic light energy into the brain from a combination of transcranial (through the skull) and intranasal (via the nasal channels) locations. In a preferred embodiment, the PBM device works in combination with a diagnostic tool to provide enhanced treatment of abnormal brain function intelligently, automatically, and unrestricted by geographical distances. |
US11633619B2 |
Systems and methods for measuring magnetic fields from solvated target molecules using a magnetoresistive sensor
A measurement system includes a container configured to contain a solvated target molecule and at least one magnetoresistive (MR) sensor device including at least one MR sensor disposed near the container and configured to measure a magnetic field generated by the solvated target molecule, each of the at least one MR sensor including a pin layer having a pinned direction of magnetization, a free layer having a direction of magnetization that varies with an applied magnetic field, and a non-conductive layer separating the pin layer and the free layer. |
US11633616B2 |
Magnetic field oscillating at several frequencies for improving efficacy and/or reducing toxicity of magnetic hyperthermia
Magnetic nanoparticles for use in a magnetic hyperthermia therapeutic treatment, prophylactic treatment or diagnosis method, wherein the magnetic nanoparticles are administered to a body part of an individual and the body part is exposed to a magnetic field oscillating at a high frequency and at a medium and/or low frequency, wherein the high frequency is 1 MHz at the most, the medium frequency is lower than the high frequency, and the low frequency is lower than the high frequency and lower than the medium frequency when it is present. |
US11633611B2 |
Feedthrough assembly and device including same
Various embodiments of a feedthrough header assembly and a device including such assembly are disclosed. The assembly includes a header having an inner surface and an outer surface; a dielectric substrate having a first major surface and a second major surface, where the second major surface of the dielectric substrate is disposed adjacent to the inner surface of the header; and a patterned conductive layer disposed on the first major surface of the dielectric substrate, where the patterned conductive layer includes a first conductive portion and a second conductive portion electrically isolated from the first conductive portion. The assembly further includes a feedthrough pin electrically connected to the second conductive portion of the patterned conductive layer and disposed within a via that extends through the dielectric substrate and the header. The feedthrough pin extends beyond the outer surface of the header. |
US11633603B2 |
Burr cap-mounted electrodes
A system provides a burr hole cap assembly configured to secure a position of a lead implanted through a burr hole in a cranium of a patient. One or more electrodes are coupled to one or more components of the burr hole cap assembly. The one or more electrode is disposed within the burr hole cap assembly for sensing signals within a brain of the patient or stimulating a portion of the brain of the patient. |
US11633602B2 |
Power efficient stimulators
This disclosure relates to a device for applying a neural stimulus. A battery supplies electrical energy at a battery voltage and an electrode applies the electrical energy to neural tissue. A circuit measures the nervous response of the tissue and a voltage converter receives the electrical energy from the battery and controls a voltage applied to the electrode based on the measured nervous response of the tissue. This direct voltage control is energy efficient because losses across a typical current mirror are avoided. Further, the control based on the measured nervous response leads to automatic compensation of impedance variation due to in-growth or change in posture. As a result, the stimulation results in a desired neural response. |
US11633601B2 |
Treatment of inflammatory disorders
Modulation of the neural activity of a nerve adjacent to the left gastro epiploic artery (LGEA) and/or a nerve adjacent to a short gastric artery (SGA) can modulate the neural activity of the sympathetic nerves that impact splenic function. This is useful for reducing inflammation and providing ways of treating inflammatory disorders. |
US11633598B2 |
Spinal cord stimulation to treat pain
A system and method for treating pain without paresthesia by spinal cord stimulation. |
US11633595B2 |
System for variably configurable, adaptable electrode arrays and effectuating software
Electrical non-invasive brain stimulation (NIBS) delivers weak electrical currents to the brain via electrodes that are affixed to the scalp. NIBS can excite or inhibit the brain in areas that are impacted by that electrical current during and for a short time following stimulation. Electrical NIBS can be used to change brain structure in terms of increasing white matter integrity as measured by diffusion tensor imaging. Together the electrical NIBS can induce changes in brain structure and function. The present methods and devices are adaptable to and configurable for facilitating the enhancement of brain performance, and the treatment of neurological diseases and tissues. The present methods and devices are advantageously designed to utilize modern electrodes deployed with, inter alia, various spatial arrangements, polarities, and current strengths to target brain areas or networks to thereby enhance performance or deliver therapeutic interventions. |
US11633585B2 |
Medical connector
A medical connector that allows ventilation of vapor used in vapor sterilization and has an internal flow route that is tightly closable without using any separate clamping device. A medical connector includes a body having an internal flow route connected to an other flow route, proximal portions included in the body and having respective one-side connection ports at which the internal flow route is connectable to the one flow route, a distal portion having an other-side connection port at which the internal flow route is connectable to the other flow route, one-side lid portion, and an other-side lid portion whose state is switchable between a closing state and a ventilating state in which the other-side lid portion covers the other-side connection port such that ventilation is allowed. |
US11633584B2 |
Sterile connector
The invention is directed to an connector comprising a first part and a second part, each provided with a contact surface and at least one non-contact surface facing away from the contact surface, at least one opening in the contact surface having an fluid connection to at least one opening of the non-contact surface, a releasable covering of the opening in the contact surface, and complementary means for mechanically coupling the parts at the contact surfaces to form the connector. The complementary means for mechanically coupling the parts are configured to mechanically interlock with each other. |
US11633582B2 |
Implantable access port including fluid handling features
An access port for subcutaneous implantation is typically connected to a catheter, a distal portion of which is disposed within a vein or other vessel of the patient. The access port described herein is configured with enhanced fluid handling features to improve fluid flow therethrough while reducing the likelihood of clotting or occlusions in the attached catheter, thus improving system patency. The access port includes a body defining a reservoir, a needle-penetrable septum covering the top opening of the reservoir, a stem including a lumen in fluid communication with the reservoir, and a volume control device positioned in the reservoir. The volume control device includes a floor designed to move from a first position below the side opening to a second position adjacent the bottom surface, and a spring element positioned between the floor and the bottom surface, the spring element biasing the floor in the first position. |
US11633577B2 |
Systems and methods for treating pulmonary edema
Various systems and methods are provided for treating pulmonary edema. In general, a pump can be configured to be implanted within a patient at risk of developing edema. The pump can be configured to pump fluid out of the patient's lungs, e.g., out of the patient's interstitial and alveolar spaces. The pump can be configured to be fully implanted within the patient's body. The pump can be configured to continuously pump fluid, or the pump can be configured to be selectively actuatable in response to a trigger event. In an exemplary embodiment, the pump can include an inflow port coupled to an inflow tube in fluid communication with a lymphatic vessel of the patient, and can include an outflow port coupled to an outflow tube in fluid communication with a vein of the patient. |
US11633572B2 |
Over-actuated hysteretic systems and methods for control of same
An over-actuated system [304], such as a catheter, having shape memory alloy (SMA) hysteretic wire actuators is controlled using a controller [300, 302] that generates a control signal [310] based on a temperature model that takes into account physical limitations of the SMA hysteretic wire actuators, and based on a hysteresis model (e.g., the Duhem model) that describes hysteresis behavior of the SMA hysteretic wire actuators. The controller preferably includes a feedback controller [302] and a reference governor [300] that generates a smart reference signal [308] from a reference signal [306] representing a desired value of an output of the system. The smart reference signal preferably minimizes an error between the reference signal and an achievable output, and the control signal preferably is generated based on the smart reference signal. |
US11633571B2 |
Rapid aspiration thrombectomy system and method
An intravascular access system for facilitation of intraluminal medical procedures within the neurovasculature through an access sheath. The system includes an aspiration or support catheter having a flexible, distal luminal portion having an inner diameter defining a lumen extending between a proximal opening at a proximal end of the luminal portion and a distal opening at a distal end of the luminal portion. The catheter has a rigid spine coupled to at least the proximal end of the luminal portion and extending proximally therefrom. The system includes a dilator having a flexible, distal dilator portion sized to be received within the lumen of the luminal portion. Associated systems, devices, and methods of use are also described. |
US11633569B2 |
Motorized telescoping medical device delivery system
A system for delivering an implantable medical device includes a handle housing. An outer sheath is coupler secured to a proximal end of an outer sheath that is configured to cover at least a portion of the implantable medical device. An outer sheath drive assembly is operably coupled to the outer sheath coupler and is configured to translate the outer sheath relative to the handle housing. An actuation shaft coupler is secured to a proximal end of an activation shaft. An actuation shaft drive assembly is operably coupled to the actuation shaft coupler and is configured to cause the actuation shaft to translate relative to the handle housing and shift the implantable medical device from a first position and a second position in which the implantable medical device is radially expanded relative to the first position. |
US11633559B2 |
Multi-mode respiratory therapy apparatus, system, and method
A respiratory therapy apparatus is operable to deliver multiple types of therapy to a patient. The apparatus includes a main housing and a nebulizer tray that selectively attaches to a bottom of the main housing. The apparatus also includes a filter housing unit having an antenna surrounding a pneumatic passage and a transponder chip coupled to the antenna. The main housing has also has an antenna that surrounds a respective pneumatic passage of a main outlet port of the apparatus. The main housing includes a reader that controls communication between the antennae. The main housing of the apparatus also has a pivotable hose support plate, a firmware upgrade port underneath part of the top wall of the housing, and a graphical user interface (GUI) that displays various user inputs for control of the apparatus and that displays various alert conditions that are detected. |
US11633557B2 |
Non-combustion type flavor inhaler and aerosol delivery method
A non-combustion type flavor inhaler comprising: an atomizer atomizing an aerosol source without burning; and a controller controlling a power output to the atomizer, wherein the controller is configured to start supply of a power output to the atomizer before start of a user's puffing action, and is configured to stop supply of a power output to the atomizer during a user's puffing action. |
US11633554B1 |
Adaptive systems and methods for delivery of a medicament
Methods and apparatuses for the therapeutic delivery of nicotine for smoking cessation, harm reduction and/or substitution. Furthermore, the devices and methods herein are useful as an alternative, general nicotine delivery system in place of tobacco combustion or high temperature (over 150 degrees C.) products. In addition, the methods and devices herein are useful for the therapeutic delivery of a drug, for reducing the cumulative drug dose and hence its potential toxic side effects, while increasing its neurophysiological and/or physiological effects. Moreover, the devices and methods herein are useful for addiction treatment or reduction. In certain embodiments, the methods are adaptable to a medicament delivery device that determines a sequence of drug doses to be delivered. Dose information may be used to control operation of the device. |
US11633550B2 |
Device for dosing liquid
The invention relates to a device for dosing liquid from a liquid-receiving element (2), in which the liquid-receiving element (2) comprises an outlet valve (1), and a dosing system is available, said dosing system consisting of a first actuating wing (4) and a second actuating wing (5), which are arranged around the liquid-receiving element (2) and can be moved in relation to each other such that they compress the liquid-receiving element (2), a mechanical dosing stop being available. |
US11633549B2 |
Apparatus, system and method of providing a fluid bag heater
The disclosure provides an apparatus, system and method of providing a flexible heater on at least one conformable substrate of a medical fluid bag. The disclosed embodiments may include providing a matched function ink set, printed onto at least one substantially planar face of the at least one substrate to form at least: at least one conductive layer capable of receiving current flow from at least one power source; at least one resistive layer electrically associated with the at least one conductive layer and comprising a plurality of heating elements capable of generating heat upon receipt of the current flow; and at least one dielectric layer capable of at least partially insulating the at least one resistive layer. |
US11633546B2 |
Palm activated drug delivery device
Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered. |
US11633544B2 |
Injection head and chemical injection device comprising same
A chemical-liquid injection head including a syringe holding unit which holds a syringe in which a piston member is slidably inserted into a cylinder member having a circular cylindrical shape, a piston driving mechanism having a ram member for moving the piston member of the syringe, and a first light emitting portion which emits light with a first color and illuminates the syringe and a second light emitting portion which emits light with a second color and illuminates the syringe. The first light emitting portion and the second light emitting portion, viewed in a posture at the time of use of the injection head, are provided at an upper side of the ram member. |
US11633541B2 |
Cartridge hold-up volume reduction
Drug delivery systems with reduced hold-up volumes are provided. The drug delivery systems include a cartridge configured to hold a liquid drug. A cartridge stopper is positioned in a first portion of the cartridge. A needle guide component is positioned within the cartridge stopper. A needle is positioned within a central opening of the needle guide. A plunger is positioned in a second portion of the cartridge. The plunger includes a fluid path pocket facing and aligned with the central opening of the needle guide component. The plunger is driven toward the cartridge stopper to expel the liquid drug from the cartridge through the needle. An end of the needle can be positioned within the fluid path pocket when the plunger is pushed against the cartridge stopper, ensuring that only a small volume of the liquid drug remains in the cartridge when delivery of the liquid drug is completed. |
US11633540B2 |
Spring straining mechanism for torsion spring based device
The present invention concerns a drug delivery device (1) comprising: a housing (2) extending along a main axis, a torsion spring (5) comprising a first spring end (4) arranged stationarily with respect to the housing (2) and a second spring end (6) capable of rotation about the main axis, a rotatable shaft (80) extending along the main axis, the rotatable shaft (80) having a non-self-locking thread (81) and being axially fixed with respect to the housing (2), a spring end retainer (82) to which the second spring end (6) is attached, the spring end retainer (82) being rotationally fixed relative to the rotatable shaft (80), and a nut member (45) engaged with the non-self-locking thread (81), the nut member (45) being axially movable by translation relative to the housing (2) to thereby travel the non-self-locking thread (81) between a first position in which the torsion spring (5) is in a relaxed state and a second position in which the torsion spring (5) is in a strained state. |
US11633539B1 |
Infusion and monitoring system
Embodiments relate to a system, comprising a timer module comprising a timer configured to set a time for a session, an infusion module comprising an infusing device configured for administering a drug to a patient, a patient monitoring module comprising a first sensor configured for monitoring a physiological condition of the patient, a drug monitoring and control module comprising a second sensor configured for monitoring a drug delivery to the patient, an alarm generating module comprising signal generator that generates an indication signal when a value of the physiological condition is outside a predefined threshold, and wherein the time for the session is dynamically adjusted during the session, and wherein the drug delivery is dynamically adjusted during the session. |
US11633538B2 |
Adjustable medium diverter
A system for modulating delivery of a fluid medium includes an injector for injecting the fluid medium during an injection cycle, a delivery catheter including a conduit for delivering the fluid medium, a manifold disposed in a fluid medium flow path between the injector and the delivery catheter, and a pulsatile generator. The pulsatile generator is configured to apply a pulsatile force to the fluid medium defined by a plurality of duty cycles during the injection cycle, each of the duty cycles including a first pressure level and a second pressure level that is lower than the first pressure level. |
US11633537B1 |
Drug delivery assembly including a pre-filled cartridge
A drug delivery assembly includes a main body and a cartridge. The body includes a housing, an adhesive pad, and a body interface that detachably associates with a cartridge interface of the cartridge. A fluid flow path extends through the body housing, between a first end configured to open a seal of the cartridge and a second end configured to enter a human body. The cartridge contains a drug reservoir having an outlet and holding a medicament. The seal prevents the medicament from exiting the reservoir and maintains pressure within the reservoir until the seal is opened by the first end of the fluid flow path when the cartridge is coupled to the main body, placing the reservoir into fluid communication with the flow path. A controller actuates a valve within the body to selectively allow and prevent flow through the flow path during an automated drug delivery routine. |
US11633530B2 |
Suction device for sucking obstruction in respiratory tract and use method therefor
A suction device includes a negative pressure generator, a connector and a mask; the negative pressure generator comprises a housing and a piston rod, wherein the housing is internally provided with a cavity, an upper end of the housing is provided with an avoidance hole communicated with the cavity, and a lower end thereof is provided with an opening communicated with the cavity; the piston rod comprises a push-pull rod and a piston sleeved on the push-pull rod, an upper end of the push-pull rod runs through the avoidance hole, and the piston is movably and hermetically connected to an inner side wall of the housing by means of a sealing ring; an upper side of the mask is provided with a through first connecting cylinder, and a lower side thereof is provided with a flexible annular pad configured to fit with the face. |
US11633527B2 |
Filtration system for preparation of fluids for medical applications
A system for filling multiple sterile containers includes a filter with an inlet port and multiple outlet ports, the outlet ports being pre-attached to sterile containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines are connected to a respective container interior. The respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. A container that is connectable to an outlet port the system has a bladder, a first tube and a second tube connected to the bladder, and a sterilizing filter. The container, the first tube and the second tube, and the sterilizing filter are sterile before water is flowed through the sterilizing filter into the bladder. |
US11633523B2 |
Method for producing cell tissue, and porous film
Provided are a method for producing a cell tissue, including a culturing step of culturing cells capable of serving as a feeder inside opening pores and communicating pores of a porous film having a plurality of the opening pores provided on a surface thereof and the communicating pores communicating mutually adjacent opening pores with one another; and a porous film including a plurality of opening pores provided on a surface thereof and communicating pores communicating mutually adjacent opening pores with one another. |
US11633522B1 |
Malleable, cryopreserved osteogenic compositions with viable cells
A bone graft composition comprising a viable, osteogenic cellular material combined with a viscous cryoprotectant that includes a penetrating cryoprotective agent and a non-penetrating cryoprotective agent. The viscosity of the cryoprotectant is such that the composition is malleable, cohesive and capable of being formed into desired shapes. |
US11633521B2 |
Biologic breast implant
The present disclosure provides tissue products produced from adipose tissues, as well as methods for producing such tissue products. The tissue products can include acellular tissue matrices for treatment of a breast. |
US11633520B2 |
Perforated tissue graft
A tissue graft for soft tissue repair or reconstruction comprising a sheet of a biopolymer-based matrix having a plurality of small perforations and a plurality of large perforations. The small perforations are sized to facilitate clotting and granulation tissue development within the perforations which, in turn, facilitates revascularization and cell repopulation in the patient. The large perforations are sized to reduce the occurrence of clotting and granulation tissue development within the perforations so that extravascular tissue fluids accumulating at the implant site can drain through the tissue graft. The large perforations enhance mammal tissue anchoring by permitting mammal tissue to compress into the perforations increasing mammal tissue contact area. |
US11633519B2 |
Dried implant composition and injectable aqueous implant formulation
A dried implant composition for preparing an injectable aqueous implant formulation that is extrudable through a tapering system and a gauge 18 cannula, including a mixture of nanocrystalline hydroxyapatite particles derived from natural bone having a size of 50 to 200 μm and fragments of naturally crosslinked fibrous collagen material that pass through a 0.5 mm sieve; an injectable aqueous implant formulation, wherein the injectable aqueous implant formulation is obtainable by hydration and homogeneous mixing; a process for preparing the injectable aqueous implant formulation; and a kit for preparing the injectable aqueous implant formulation. |
US11633512B2 |
Method for disinfecting soils or other agricultural growing media
The invention relates to a method for disinfecting soils or other agricultural growing media, characterised by comprising the following steps: obtaining a soil or other agricultural growing medium at their field capacity; treating the soil or medium at the field capacity of the previous step with ozonated water, wherein the ozonated water is prepared in situ with ozone-production equipment connected to the water supply; allowing a period of time to pass after the treatment with ozone; and inoculating the disinfected soil or agricultural medium with at least one species of beneficial microorganism. |
US11633511B2 |
Production of immune-response-stimulating aerosols by non-thermal plasma treatment of airborne pathogens
Infectious diseases can be transmitted to humans, or between humans and animals, by airborne viruses and bacteria, known as infectious aerosols. Current protective measures that individuals can take to avoid inhaling such aerosols are either marginally effective (personal face masks) or impractical (self-contained breathing apparatuses). Building ventilation systems employing high-efficiency filters to prevent distribution of such aerosols suffer from high energy costs and high filter replacement costs. The development of conventional, intramuscularly administered vaccines takes months or years to produce enough doses to protect a population from a rapidly spreading infectious disease. Airborne viruses and bacteria have been shown to be completely inactivated when exposed to non-thermal plasmas. Results indicate the potential for sub-lethal exposures of airborne pathogens could render them unable to spark an infection in a host, but still retain the necessary surface proteins to cause an immune response in the host. |
US11633509B2 |
Ultraviolet ray irradiation device and ultraviolet ray blocking unit
To provide an ultraviolet ray irradiation device by preventing leakage of ultraviolet rays from an insertion opening through which a hand on which a glove is mounted is inserted into a sterilization chamber. The device includes: an ultraviolet ray blocking balloon disposed in an insertion opening; a pressurized gas supplying and discharging device which supplies a gas under pressure to the balloon and discharges from it; an insertion depth detection unit which outputs an insertion hand depth detection signal; a controller of an ultraviolet ray irradiation and a pressurized gas supplying and discharging, wherein the balloon forms an opening which allows an insertion and a removal of the hand before the gas is supplied, and it is inflated with the supply of the gas so as to be brought into close contact with a wrist portion of the glove, and it is deflated with a discharge of the gas. |
US11633507B2 |
HER2 binders
Imaging agents comprising an isolated polypeptide conjugated with a radionucleide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents. |
US11633505B2 |
Nuclear magnetic resonance diagnostic agent, and method for detecting or diagnosing state of cell, tissue or organ in subject using same
[Problem]To provide a nuclear magnetic resonance diagnostic agent that has a lower toxicity to organisms and reduced side effects and yet has a site specificity toward a specific cell, tissue, organ, etc.[Solution]When ALA or an ALA derivative is administered in vivo, a metabolite thereof is accumulated in a specific cell, tissue, organ, etc. Focusing on this phenomenon, a nuclear magnetic resonance analysis was performed on a site wherein the metabolite of ALA that had been administered in vivo would be possibly accumulated. As a result, it was surprisingly found that ALA and an ALA derivative are useful as a diagnostic agent whereby the aforesaid problem can be solved. |
US11633504B2 |
Nucleic acids encoding clotting factor variants and their use
Disclosed herein are novel variants of clotting factors VII, VIII, and IX and their use, for example, in methods of treating a subject with a clotting disorder, such as hemophilia A or hemophilia B. |
US11633501B2 |
Anti-STEAP2 antibodies, antibody-drug conjugates, and bispecific antigen-binding molecules that bind STEAP2 and CD3, and uses thereof
The protein known as six-transmembrane epithelial antigen of prostate 2 (STEAP2) is highly expressed in prostate cancer and is associated with the expression of other prostate cancer-associated genes. The present invention provides novel full-length human IgG antibodies that bind to human STEAP2 (monospecific antibodies). The present invention also provides novel bispecific antibodies (bsAbs) that bind to both STEAP2 and CD3 and activate T cells via the CD3 complex in the presence of STEAP2-expressing tumors. According to certain embodiments, the present invention provides bispecific antigen-binding molecules comprising a first antigen-binding domain that specifically binds human and monkey CD3, and a second antigen-binding molecule that specifically binds humanSTEAP2. In certain embodiments, the bispecific antigen-binding molecules of the present invention are capable of inhibiting the growth of tumors expressing STEAP2. The bispecific antigen-binding molecules of the invention are useful for the treatment of prostate diseases and disorders in which an upregulated or induced STEAP2-targeted immune response is desired and/or therapeutically beneficial. For example, the bispecific antibodies of the invention are useful for the treatment of prostate cancers, including castrate-resistant prostate cancer. The present invention also includes anti-STEAP2 antibody drug conjugates which inhibit tumor growth in vivo. |
US11633500B2 |
Antibody drug conjugates (ADC) that bind to CD37 proteins
Antibody drug conjugates (ADC's) that bind to CD37 protein and variants thereof are described herein. CD37 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention in some embodiments provide a therapeutic composition for the treatment of cancer. |
US11633499B2 |
Anti-TMEM-180 antibody, anticancer drug and cancer testing method
An object of the present invention is to provide an anticancer drug capable of treating cancer by finding a target molecule specifically expressed in cancer cells and by specifically acting on the target molecule, and to provide a cancer testing method including a step of measuring the target molecule in a sample. The present invention provides an anticancer drug containing, as an active ingredient thereof, an anti-transmembrane protein 180 (TMEM-180) antibody or an antigen-binding fragment thereof. In addition, the present invention provides a cancer testing method including a step of measuring the amount of TMEM-180 in a sample collected from a subject. |
US11633498B2 |
Muscle targeting complexes and uses thereof for treating myotonic dystrophy
Aspects of the disclosure relate to complexes comprising a muscle-targeting agent covalently linked to a molecular payload. In some embodiments, the muscle-targeting agent specifically binds to an internalizing cell surface receptor on muscle cells. In some embodiments, the molecular payload inhibits expression or activity of a DMPK allele comprising a disease-associated-repeat. In some embodiments, the molecular payload is an oligonucleotide, such as an antisense oligonucleotide or RNAi oligonucleotide. |
US11633497B2 |
Anti-c-Met antibody drug conjugates
The present disclosure provides c-Met antibody drug conjugates (ADCs), including compositions and methods of using such ADCs. |
US11633496B2 |
Muscle targeting complexes and uses thereof for treating dystrophinopathies
Aspects of the disclosure relate to complexes comprising a muscle-targeting agent covalently linked to a molecular payload. In some embodiments, the muscle-targeting agent specifically binds to an internalizing cell surface receptor on muscle cells. In some embodiments, the molecular payload promotes the expression or activity of a functional dystrophin protein. In some embodiments, the molecular payload is an oligonucleotide, such as an antisense oligonucleotide, e.g., an oligonucleotide that causes exon skipping in a mRNA expressed from a mutant DMD allele. |
US11633495B2 |
Compounds and compositions for immunotherapy
The present invention relates to compounds for targeted immunotherapy, as well as compositions comprising the same. Further, the present invention relates to the use of the compounds in the treatment of diseases such as cancer. |
US11633491B2 |
Linker composition comprising silica-forming peptides
The present disclosure relates to the use of silica-forming peptides (SFPs) Volp1 and Salp1 for protein fusion tags for protein purification, silica formation and self-encapsulation, and controlled release of biomolecules. After preparing a fusion protein containing the Volp1 or Salp1 peptide at the C-terminal of the protein, the adsorption conditions for silica (SiO2) surface were optimized. As a result, a high-purity fusion protein could be purified without an additional tag for purification. The fusion protein containing the silica-forming peptide was self-encapsulated and stably immobilized in the silica matrix through reaction with a silica precursor. The Volp1 and Salp1 peptides showed stronger adsorption ability for silica than the previously known R5 peptide. Using these characteristics, a silica complex wherein two proteins are encapsulated was prepared by mixing the R5 fusion protein with the Volp1 or Salp1 fusion protein. The resulting controlled release system allows the release of the R5 fusion protein in the first step and release of the Salp1 fusion protein in the second step based on the difference in adsorption affinity. |
US11633490B2 |
ASH1L degraders and methods of treatment therewith
Provided herein are small molecules comprising a first domain that binds to ASH1L and a second domain that facilitates ASH1L degradation. In particular, ASH1L-targeting proteolysis targeting chimeras (PROTACs) and methods of use thereof for the treatment of disease (e.g., acute leukemia, solid cancers and other diseases dependent on activity of ASH1L) are provided. |
US11633489B2 |
Iron carbohydrate complex for treatment of iron deficiency of a fetus or an infant
Disclosed herein is a pharmaceutical composition comprising an iron carbohydrate complex for use in a method for treatment or prevention of an iron deficiency of a fetus or an infant, wherein the iron carbohydrate complex is administered to the mother of the fetus or infant. |
US11633484B2 |
Method for improving the oral bioavailability of a drug
The invention is in the field of medical sciences. It provides new pharmaceutical methods and preparations. In particular, the invention relates to a method for increasing the oral bioavailability of drugs. The invention also provides new compositions comprising a drug covalently attached to a saccharide as in formula (I) below. More in particular, the invention relates to a method for increasing the oral bioavailability of a drug by covalently attaching a sugar-linked, N-substituted or unsubstituted carbamoylalkylidene moiety to a hydroxyl or thiol group of a drug, wherein the substituents are as defined in the claims. |
US11633482B2 |
Conjugates and preparation and use thereof
A compound for forming a conjugate with an active agent such as an oligonucleotide having a structure represented by Formula (321). The present disclosure also provides a corresponding conjugate. The conjugate of the present disclosure can specifically target hepatocytes, thereby effectively solve the problems associated with delivery of oligonucleotide drugs in vivo, and have low toxicity and excellent delivery efficiency while maintaining high stability for the delivered oligonucleotide. |
US11633476B2 |
Stable formulations of programmed death receptor 1 (PD-1) antibodies and methods of use thereof
The invention relates to stable formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. In some embodiments the formulations of the invention comprise between 5-200 mg/mL anti-PD-1 antibody, or antigen binding fragment thereof. The invention further provides methods for treating various cancers with stable formulations of the invention. In some embodiments of the methods of the invention, the formulations are administered to a subject by intravenous or subcutaneous administration. |
US11633472B2 |
Compositions
The disclosure defined by this invention is an immunogenic composition comprising a viral antigen, a sugar and/or polyol, an adipate buffer, calcium ions and/or magnesium ions, and one or more positively charged amino acids. |
US11633471B2 |
Compositions and methods for reducing serum triglycerides
An immunogen generally includes a virus-like particle and an antigen linked to the virus-like particle. The antigen includes an antigenic portion of a polypeptide, wherein the polypeptide inhibits lipoprotein lipase (LPL) activity by binding to LPL. In some embodiments, the polypeptide is at least a portion of angiopoietin-like 3 (ANGPTL3). In other embodiments, the polypeptide is at least a portion of angiopoietin-like 4 (ANGPTL4). In other embodiments, the polypeptide at least a portion of angiopoietin-like 8 (ANGPTL8). In some embodiments, the virus-like particle is a Qbeta immunogenic carrier. In some of these embodiments, the antigen is linked to the virus-like particle through a Gly-Gly-Gly-Cys linker at the C-terminal of the antigen. |
US11633459B2 |
GIP derivatives and uses thereof
The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particular the invention relates to such peptides that are agonists at the GIP receptor and to their use in weight management or for treatment of diseases such as obesity, diabetes or non-alcoholic steatohepatitis (NASH). |
US11633451B2 |
Antimicrobial peptide stimulating cleansing composition
A topical cleansing composition for stimulating the production of antimicrobial peptides on the skin is disclosed. The topical cleansing composition includes an active ingredient comprising one or more of a natural extract and a polypeptide; one or more surfactants; and water. The topical cleansing composition increases the concentration of antimicrobial peptides on skin, as compared to an otherwise identical topical composition without the active ingredient. |
US11633448B2 |
Controlled-release and stratified cyclodextrin inclusion complex vehicles
The invention provides cyclodextrin inclusion complex delivery vehicles formulated for oral delivery, in which the cyclodextrin inclusion complex comprising N-acetylcysteine and acetaminophen as stacked guest molecules within the cyclodextrin cavity is provided together with an enzyme having a cyclodextrin-degrading activity capable of digesting the cyclodextrin, so that upon delivery of the vehicle to a target the enzyme is activated and releases N-acetylcysteine and acetaminophen from the cyclodextrin cavity. In alternative aspects, these cyclodextrin inclusion complex delivery vehicles are for example provided in the form of medicaments, food ingredients, medical food ingredients, nutritional supplement ingredients, dietary supplement ingredients, herbicides, insecticides, fungicides, animal repellents, pheromones, plant growth regulators, fragrances, fabrics or packaging materials. |
US11633443B2 |
Algal extract comprising sulphated and non-sulphated polyanionic polysaccharides and uses thereof
The present invention relates to an algal extract comprising sulphated and non-sulphated polyanionic polysaccharides, to a method for preparing an algal extract as well as to its therapeutic and prophylactic applications. |
US11633442B2 |
Methods for combining adoptive T cell therapy with oncolytic virus adjunct therapy
The present invention relates to augmenting the effects of adoptive T cell therapy, such as TVAX Immunotherapy, using adjunct treatment with an oncolytic virus, such as a vaccinia virus, to treat various types of cancer or other proliferative disorders. Immunomodulatory compounds can be used to further augment to effects of the therapy. |
US11633438B2 |
Cryoprotectants for freeze drying of lactic acid bacteria
The present invention comprises the discovery and development of an effective cryoprotectant composition, without containing skim milk or any other animal-derived compounds, to achieve long-term stability of freeze-dried lactic acid bacteria (LAB), at different temperatures, whereby the retention of viability of the freeze-dried LAB after 6 months of storage, preferably after 9 months of storage, more preferably after 12 months of storage is more than 50%. The invention is in the field of producing freeze dried bacteria, in particular Lactic acid bacteria. More in particular, the invention relates to the use of a novel combination of cryoprotectants for increasing the viability of bacteria after freeze drying, improving the texture of the lyofilized cake for easy grinding and improving the long term stability of the freeze dried bacteria at different temperature conditions. The invention further relates to such freeze dried bacteria for use in food industry or in human or animal health applications. More in particular, the invention relates to the increased viability and long-term storage of recombinant bacteria capable of expressing heterologous proteins or peptides and administered to humans or animals for therapeutic or vaccination purposes. |
US11633433B2 |
Anti-bacterial composition against TH1 cell-inducing bacteria
With the aim of proving an antibacterial composition against oral bacteria and the like capable of inducing Th1 cell proliferation or activation in an intestinal tract, the present inventors have found out that bacteria that suppress colonization and the like of the oral bacteria and the like in the intestinal tract are present in an intestinal microbiota. Moreover, the present inventors have succeeded in isolating intestinal bacteria that suppress intestinal colonization and the like of oral bacteria and the like. |
US11633432B2 |
Amniotic fluid topical formulation
A human amniotic fluid formulation has been developed for topical application to the eye, which is useful for the treatment of ocular diseases and injuries including dry eyes, Sjogren's Syndrome, cataracts, burns and injuries to the eye tissues. The formulation is a sterile de-cellularized human amniotic fluid (D-HAF), devoid of amniotic stem cells and elements of micronized membrane or chorion particles. Methods for treating, or preventing various ocular diseases, injuries and disorders using the formulation, optionally in combination with one or more therapeutic, prophylactic or diagnostic agents are described. |
US11633431B2 |
Cardiac stem cells for cardiac repair
Embodiments of the disclosure concern compositions and methods of use related to particular c-kit+ mesenchymal cells, including cardiac stem cells, obtained from a pediatric or neonatal individual. In specific embodiments, the cells, or conditioned medium or partial or total secretomes thereof, are provided in an effective amount to an individual in need thereof. |
US11633428B2 |
Targeting of SRC-3 in immune cells as an immunomodulatory therapeutic for the treatment of cancer
The present disclosure concerns methods and compositions related to cancer treatment comprising targeting of SRC-3 in immune cells, including T cells such as T regulatory cells. The targeting of SRC-3 in T regulatory cells in particular is effective to eradicate tumors in mammals. In specific cases, the T regulatory cells are subjected to CRISPR ex vivo to produce cells suitable for adoptive cell transfer. In some cases, one or more agents that target SRC-3 are also administered to the individual and/or are exposed to the cells prior to administration. |
US11633420B2 |
Method of treating leukemia
The present invention relates to methods of treating disorders in which DOT1L-mediated protein methylation plays a part, such as cancer, by administering DOT1L inhibitor compounds and pharmaceutical compositions to subjects in need thereof. |
US11633419B2 |
Methods of treating, reducing the incidence of, and/or preventing ischemic events
Methods of treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing percutaneous coronary intervention (PCI), comprising administering to the patient a pharmaceutical composition comprising cangrelor. The method may further comprise administering an additional therapeutic agent to the patient, the additional therapeutic agent comprising bivalirudin or a P2Y12 inhibitor. Pharmaceutical compositions useful for treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing PCI. The pharmaceutical compositions comprise cangrelor, and optionally bivalirudin. Methods of preparing a pharmaceutical composition for treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing PCI, comprising admixing cangrelor with one or more pharmaceutically acceptable excipients. An ischemic event may include stent thrombosis, myocardial infarction, ischemia-driven revascularization, and mortality. |
US11633418B2 |
Deoxyribonucleoside monophospate bypass therapy for mitochondrial DNA depletion syndrome
The invention relates generally to a pharmacological therapy for a human genetic diseases, specifically mitochondrial DNA depletion syndromes, and more specifically, thymidine kinase 2 (TK2) deficiency. The pharmacological therapy involves the administration of at least one deoxyribonucleoside monophosphate, or mixtures thereof. For the treatment of TK2 deficiency, the pharmacological therapy involves the administration of either deoxythymidine monophosphate (dTMP) or deoxycytidine monophosphate (dCMP), or mixtures thereof. This molecular bypass approach is applicable to other disorders of unbalanced nucleotide pools, especially those found in mitochondrial DNA depletion syndrome. |
US11633415B2 |
Compounds and methods useful for treating or preventing cancers
The present invention includes CSNK1A1 inhibitors that are useful in treating or preventing a cancer in a subject. In certain embodiments, the cancer comprises a hematological cancer, such as but not limited to acute myeloid leukemia (AML) and/or MDS (myelodysplastic syndrome, including 5q-MDS). In other embodiments, the cancer comprises colon cancer. |
US11633412B2 |
Nutritional formulations including human milk oligosaccharides and antioxidants and uses thereof
Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases. |
US11633411B2 |
Methods of treating sepsis using anti-sepsis lipid A (ASLA) based therapeutics
The present invention provides a method of treating sepsis in a subject, comprising administering to the subject an effective amount of a compound of the formula wherein R1 and R2 may be H, OH, protonated phosphate, a phosphate salt, a sugar phosphonate, or a mono-, di- or poly-saccharide, R3 may be OH or a mono-, di- or poly-saccharide, R4, R5, R6 and R7 may be an alkyl or alkenyl chain of up to 13 carbons (for a chain of 16 carbons), and R8, R9, R10 and R11 may be H, OH, or an alkyl or alkenyl ester of up to 16 carbons, or a salt thereof. |
US11633410B2 |
Compositions and methods for the treatment of meibomian gland dysfunction
Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction. |
US11633408B2 |
Prevention of adverse effects caused by CD3 specific binding domains
The present invention relates to a glucocorticoid (GC) for use in the amelioration, treatment or prophylaxis of neurological/psychiatric adverse events caused by a CD3 binding domain. Kits comprising a GC, a CD3 binding domain and instructions for use which indicate that the GC is to be employed for the treatment amelioration and/or prophylaxis of neurological adverse events caused by said CD3 binding domain, are also disclosed. |
US11633405B2 |
Steroid hormone pharmaceutical formulations
This disclosure provides pharmaceutical compositions for delivering estradiol to a subject in need thereof, as well as methods of administering the compositions, and methods of using them. |
US11633400B2 |
Crystalline salt comprising 5-methyl-(6S)-tetrahydrofolic acid and 4-(2-hydroxyethyl)-morpholine
The present invention refers to a crystalline salt comprising 5-methyl-(6S)-tetrahydrofolic acid and 4-(2-hydroxyethyl)-morpholine wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to 4-(2-hydroxyethyl)-morpholine is from 1:0.3 to 1:2.0 (in mol/mol) and/or hydrates and/or solvates thereof as well as to a process of obtaining the same. |
US11633399B2 |
Treatment of skin disorders with compositions comprising an EGFR inhibitor
This invention relates to compositions and methods of treatment of skin or mucosal disorders by administration of compositions comprising at least one EGFR inhibitor, such as topical compositions comprising erlotinib. The compositions of this invention are useful for the treatment, prevention or amelioration of skin or mucosal disorders like psoriasis, palmoplantar psoriasis, acquired palmoplantar keratosis, eczema, ichtyosis vulgaris, non-melanoma skin cancer, actinic keratosis, a keratinization skin disorder, a keratinization mucosal disorder, pachyonychia congenita, hidradenitis suppurativa, Gorlin syndrome, prurigo nodularis and prurigo pigmentosa. |
US11633397B2 |
Use of modulators of CCR5 in the treatment of cancer and cancer metastasis
This disclosure is directed, in part, to a method of determining whether a subject having cancer is at risk for developing metastasis of the cancer. In one embodiment, the method comprises (a) obtaining a biological sample from the subject having cancer; (b) determining CCR5 expression level and/or expression level of at least one of CCR5 ligands in the biological sample; and (c) if the expression level of CCR5 and/or of at least one of CCR5 ligands determined in step (b) is increased compared to CCR5 expression level and/or expression level of at least one of CCR5 ligands in a control sample, then the subject is identified as likely at risk for developing metastasis of the cancer. |
US11633396B2 |
Immediate release pharmaceutical formulation of 4-[3-(4- cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H- phthalazin-1-one
The present invention relates to a pharmaceutical formulation comprising the drug 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one in a solid dispersion with a matrix polymer that exhibits low hygroscopicity and high softening temperature, such as copovidone. The invention also relates to a daily pharmaceutical dose of the drug provided by such a formulation. In addition, the invention relates to the use of a matrix polymer that exhibits low hygroscopicity and high softening temperature in solid dispersion with 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one for increasing the bioavailability of the drug. |
US11633389B2 |
Methylphenidate extended release chewable tablet
An oral methylphenidate extended release tablet is described, which can be scored and still retain its extended release profile. The tablet contains a combination of an uncoated methylphenidate-ion exchange resin complex, a barrier coated methylphenidate-ion exchange resin complex-matrix, and an uncomplexed methylphenidate active component. Following administration of a single dose of the extended release methylphenidate chewable tablet, a therapeutically effective amount of methylphenidate is reached in less than about 20 minutes and the composition provides a twelve-hour extended release profile. |
US11633387B2 |
Methods of treating Fabry patients having renal impairment
Provided are methods for treatment of Fabry disease in patients having HEK assay amenable mutations in α-galactosidase A. Certain methods comprise administering migalastat or a salt thereof every other day, such as administering about 150 mg of migalastat hydrochloride every other day. |
US11633385B2 |
Combination compositions for treatment of cancer
Provided are methods for treating cancer in a patient by administering at least one antibiotic selected from the group consisting of clofazimine, rifabutin and clarithromycin, in combination with an aryladamantane compound. In an embodiment, the aryladamantane compound is [3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide], or a pharmaceutically acceptable salt thereof. |
US11633384B2 |
Methods of treating hepatic encephalopathy
The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin. |