最新美国发明专利第2022-12-13期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US11525135B2	TLR3 ligands that activate both epithelial and myeloid cells The invention relates to a composition comprising a double-stranded RNA (dsRNA) having two complementary strands, comprising at least one block of poly A and the complementary block of poly U, each strand having a length of between 50 and 200 bases, preferably between 55 and 200 bases, and a pharmaceutically acceptable vehicle, carrier or excipient, for use in a method of treating a cancer expressing a TLR3 receptor.
US11525134B2	Devices, systems and methods for ultra-low volume liquid biopsy Provided herein are devices, systems, kits and methods for obtaining genetic information from cell-free fetal nucleic acids in ultra-low amounts of biological samples. Due to the convenience of obtaining ultra-low amounts of samples, devices, systems, kits and methods can be at least partially employed at a point of need.
US11525130B2	Process and system for obtaining botulinum neurotoxin Rapid, animal protein free, chromatographic processes and systems for obtaining high potency, high yield botulinum neurotoxin for research, therapeutic and cosmetic use.
US11525129B2	Lactase enzymes with improved properties Disclosed are peptides and dimeric peptides exhibiting beta-galactosidase enzyme activity, as well as methods for producing a dairy product using them, and dairy products made by such methods. In some embodiments, the peptides exhibit beta-galactosidase enzyme activity at low and/or high temperatures.
US11525125B2	Modified helicases The invention relates to a new method of characterising a target polynucleotide. The method uses a pore and a Dda helicase. The helicase controls the movement of the target polynucleotide through the pore. The invention also relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
US11525124B2	Purification of polymerase complexes Disclosed are methods for isolating polymerase complexes from a mixture of polymerase complex components. The polymerase complexes can comprise a nanopore to provide isolated nanopore sequencing complexes. The methods relate to the positive and negative isolation of the polymerase complexes and/or nanopore sequencing complexes. Also disclosed is a nucleic acid adaptor for isolating active polymerase complexes, polymerase complexes comprising the nucleic acid adaptor, and methods for isolating active polymerase complexes using the nucleic acid adaptor.
US11525122B2	Microorganisms with enhanced carbon monoxide availability and use thereof The present invention relates to a protein variant, a microorganism with enhanced carbon monoxide (CO) availability comprising the variant, and a use thereof.
US11525120B2	Stem cell derived islet differentiation Provided herein are methods of producing β cells and precursors thereof utilizing a Wnt signaling inhibitor or PKC activator, or both. Also provided herein are in vitro cultures comprising said cells, methods of treating a subject with a disease characterized by high blood sugar levels over a prolonged period of time by administering said cells, and devices for encapsulating said cells.
US11525119B2	Immune cells derived from induced pluripotent stem cell Embodiments disclosed here are production methods and compositions of engineered immune cells, such as B or T lymphocytes, from limited lineage myeloid progenitor cells, or from pluripotent stem cells, or from multilineage hematopoietic progenitor cells comprising the addition of various cell differentiation transcription factors and inhibiting epigenetic histone methylations in said cells.
US11525116B2	Date palm medium compositions and methods Disclosed are date palm compositions and methods of use of such compositions. Such compositions may be used as part of a growth medium for culture of microorganisms. In certain embodiments, date palm extracts of the disclosure are used as part a culture medium to grow Lactobacilli.
US11525114B2	System and method for vaporized hydrogen peroxide cleaning of an incubation chamber A method is provided for vaporized hydrogen peroxide cleaning of a chamber. The method includes altering a temperature of air in the chamber from an initial temperature to a sterilization temperature over a first time period. The method also includes injecting vaporized hydrogen peroxide into air in the chamber to alter a relative humidity of hydrogen peroxide vapor in the chamber to a sterilization level over the first time period. The method also includes maintaining the temperature at the sterilization temperature and the relative humidity at the sterilization level over a second time period. The method also includes reducing the relative humidity from the sterilization level to a safe level over a third time period. In one embodiment, the method is provided for vaporized hydrogen peroxide cleaning of an interior chamber of an incubation container. In other embodiments, the incubation chamber featured in the method is provided.
US11525113B2	Bioreactor assembly The present invention relates to a bioreactor assembly comprising a plurality of trays (30) for holding a cell culture bag, a holder (2) on which the trays are mounted side by side to form a first series of trays rocking mechanism (4) for rocking the trays, the rocking mechanism (4) being operatively connected to each of the trays (30). The invention also relates to a bioreactor system (100) comprising at least one bioreactor assembly.
US11525108B2	Beverage maker A beverage maker may include a fermenter having an opening, a fermentation lid configured to cover the opening of the fermenter, a gas discharge channel configured to communicate with an inside of the fermenter, a gas discharge valve connected to the gas discharge channel, and a gas discharge end fitting through which a gas passing through the gas discharge valve passes and which is provided with a mesh.
US11525103B2	Docosahexaenoic acid-containing oil and method for producing same Docosahexaenoic acid-containing oil containing docosahexaenoic acid in a concentration of 40 wt. % or more of the total weight of fatty acids in the oil, and having an endothermic peak temperature determined by differential scanning calorimetry (DSC) of 15° C. or lower; a biomass including the same; and a method for producing docosahexaenoic acid-containing oil including obtaining a biomass by culturing microorganisms of the genus Aurantiochytrium capable of producing this docosahexaenoic acid-containing oil, recovering the biomass after culture, and extracting the oil from the biomass after recovery.
US11525093B2	Direct steam injection (DSI) heating and use in bitumen froth treatment operations Direct steam injection (DSI) heating techniques can use a heater to heat a process stream in bitumen froth treatment. The DSI heater can include a diffuser with multiple side-by-side rows of outlets perpendicular to a longitudinal axis of the diffuser, and a piston plug that moves axially within the diffuser to selectively cover rows of outlets to vary steam injection. The piston plug has first and second annular seals and is moved between different axial positions in a stepwise fashion such that when one or more rows of outlets are completely covered, the first annular seal is located in between adjacent rows and the second annular seal abuts against the diffuser to inhibit passage of steam so as to prevent cavitation. The DSI heater can include various other features, such as particular seal unit constructions and diffuser outlet configurations.
US11525092B2	Process for extracting crude oil from substrates A process allows the extraction of heavy hydrocarbon compounds from solid substrates in an economical and efficient fashion. Materials containing heavy hydrocarbons (i.e. oil sands or roofing shingles) are broken up into an auger and then mixed with light hydrocarbons. Subsequently, the resulting slurry is shaken to separate fluids from solids, and the fluids are subjected to one or more filtering processes to remove waste sediment. These filtering processes may include a series of one or more of centrifuges and nozzle purifier machines. Filtered fluids are distilled to separate heavy hydrocarbons from light hydrocarbons. Simultaneously, the solids are heated to remove the remaining light hydrocarbons as vapors. Light hydrocarbons are cooled in a condenser and coalesced in a holding tank, wherefrom they may be recirculated into the process and used repeatedly. The now-isolated heavy hydrocarbons resulting from the distillation process may be removed as a purified product.
US11525087B2	Dielectric devices and methods of fabrication Self-aligned liquid crystal materials and structures are disclosed. The structures can exhibit piezoelectric and flexoelectric properties.
US11525086B2	Paper sheet mulches and methods of making the same The present disclosure provides novel paper sheet mulch products having benefits over prior sheet mulches, which may include brown or recycled fibers, as well as additives, such as opacity, water-resistant, and strength additives, resulting in mulch products with an improved combination of basis weight, stretch, strength, opacity, and/or water-resistance characteristics.
US11525085B2	Process to manufacture novel inhibited hydrofluoric acid composition A process for controlling the heat generated during the manufacture an inhibited hydrofluoric acid aqueous composition comprising: hydrofluoric acid in solution; a weak base; and an alkanolamine; said process comprising the steps of: providing a pre-determined amount of weak base; adding a pre-determined amount of said hydrofluoric acid to said weak base and obtaining a solution; adding said alkanolamine to the resulting solution of hydrofluoric acid and weak base; mixing until all components are dissolved; wherein said alkanolamine and hydrofluoric acid are present in a molar ratio of at least 1:1.
US11525083B2	Core shell quantum dot, production method thereof, and electronic device including the same A quantum dot comprising zinc, tellurium, and selenium and not comprising cadmium, wherein a maximum luminescent peak of the quantum dot is present in a wavelength range of greater than about 470 nanometers (nm) and a quantum efficiency of the quantum dot is greater than or equal to about 10%, and wherein the quantum dot comprises a core comprising a first semiconductor nanocrystal and a semiconductor nanocrystal shell disposed on the core.
US11525078B2	Non-toxic high-density fluid for completion applications A modified high density brine for use in subterranean drilling and completion operations. The modified high density brine includes the addition of high density particle addition that can optionally be surface-modified. The resultant modified high density brine eliminates the need for toxic, corrosive, and costly ZrBr2 additions or other ionic additives to boost the density of the modified high density brine to 15-17 lbs./gallon or greater.
US11525077B2	Geopolymer concretes for energy storage applications A geopolymer thermal energy storage (TES) concrete product comprising at least one binder; at least one alkali activator; at least one fine aggregate with high thermal conductivity and heat capacity; and at least one coarse aggregate with high thermal conductivity and heat capacity.
US11525072B2	Materials and methods for chemical mechanical polishing of ruthenium-containing materials A chemical mechanical polishing (CMP) slurry composition includes an oxidant including oxygen, and an abrasive particle having a core structure encapsulated by a shell structure. The core structure includes a first compound and the shell structure includes a second compound different from the first compound, where a diameter of the core structure is greater than a thickness of the shell structure, and where the first compound is configured to react with the oxidant to form a reactive oxygen species.
US11525070B2	(Per)fluoropolyether polymers and use thereof The present invention relates to novel (per)fluoropolyether (PFPE) polymers, to a process for their manufacture and to their use as additives in coating compositions.
US11525068B2	Method of producing an elastic coating and an elastic coating The present invention relates to a method of producing an elastic coating which is suitable for waterproofing, by using film forming onto a solid surface, textile or mesh. In this method, a dispersion which comprises i) one or more adhesives and/or coagulating aggregates, mainly in solid form, ii) one or more polymers, and iii) one or more surface-active agents, is brought into contact with a coagulator of the surface-active agent of the dispersion. The present invention also relates to a coating which is prepared by using the present method.
US11525067B2	Modification method of substrate surface, and composition and polymer A modification method of a surface of a substrate includes: applying a composition on a surface of a metal substrate, and heating a coating film formed by the applying, wherein the composition contains: a polymer having a first structural unit that includes an aromatic ring, and a second structural unit that includes an ethylenic double bond; a thermal acid generating agent; and a solvent, wherein the polymer has a functional group capable of bonding to a metal atom in the metal substrate.
US11525054B2	Thermosetting epoxy resin composition for the preparation of articles for electrical engineering, and the articles obtained therefrom A multiple component anhydride-free, thermosetting epoxy resin composition comprising, (A) at least one epoxy resin, and (B) at least one curing agent selected from the group of (b1) a polyetheramine of the formula (1) (Formula (1)), wherein x is a number of from 2 to 8, and (b2) a polyetheramine with at least one terminal end group of the formula (2) (Formula (2)), and (C) at least one epoxy silane, is, in particular, suitable for the manufacture of instrument transformers and dry-type transformers by casting, potting and encapsulation processes, wherein said articles exhibit good mechanical, electrical and dielectrical properties.
US11525052B2	Thermoplastic styrene copolymer resin composition with improved UV resistance Thermoplastic styrene copolymer resin composition comprising: (a1) at least one styrene-acrylonitrile copolymer component A1, (a2) at least one acrylonitrile styrene acrylate graft copolymer A2 as impact modifier, (a3) optionally at least one thermoplastic polymer A3 other than components A1 and A2, (b) at least one transition metal oxide pigment B, (cl) at least one hindered amine UV light stabilizer C1, (c2) optionally at least one UV absorber C2 different from Cl, (d) optionally further polymer additives D, other than components B, C1, C2, and E, and (e) optionally one metal scavenger component E, wherein at least 99.0 wt.-% of the transition metal oxide pigment B consist of transition metal atoms and oxygen atoms.
US11525050B2	Polymer composition with improved stress whitening resistance A polymer composition is provided with improved stress whitening resistance, having at least one thermoplastic polymer material and a dielectric liquid. A process for preparing the polymer composition, a cable having at least one electrically insulating layer obtained from the polymer composition, and a process for preparing the cable are also provided.
US11525049B2	Polar additive for the synthesis of copolymers of vinylaromatic monomer and conjugated diene monomer having high vinylaromatic and low vinyl contents The present invention relates to the use of N,N′,N″-substituted hexahydro-1,3,5-triazine in the anionic polymerization of conjugated diene monomer and vinylaromatic monomer. Use of this polar additive produces copolymers having both high vinylaromatic and low vinyl contents, while the blockiness of the vinylaromatic unit can be tailored.
US11525047B2	Recycling of superabsorbent polymer with an extensional flow device Poly(acrylic acid)-based superabsorbent polymer (SAP) in a feed stream is converted into poly(acrylic acid) (PAA) in an extensional flow device. The total energy used to degrade the SAP into PAA is less than about 50 MJ/kg SAP.
US11525046B2	Foam A foam containing a nitrile group-containing conjugated diene copolymer and a urethane polymer, wherein relative to 100 wt % of the sum of the nitrile group-containing conjugated diene copolymer and the urethane polymer, the nitrile group-containing conjugated diene copolymer is present in an amount of less than 90 wt % and the urethane polymer is present in an amount of more than 10 wt %, the nitrile group-containing conjugated diene copolymer contains ethylenically unsaturated nitrile monomer units in an amount of more than 31 wt %, the foam has a density of 0.08 to 0.30 g/cm3, and in observation of an arbitrary cross section of the foam, air bubble cross sections present in the cross section have an average diameter of 350 μm or less, and the number of air bubble cross sections with a diameter of 0.6 mm or more present in the cross section is 0.062 per mm2 or less.
US11525045B2	Chemically modified polyesters and process for making Chemically modified polyesters, foamable compositions thereof that form low density foams, and methods of making the foamable compositions and foams are disclosed. The compositions comprise an amorphous copolyester, or amorphous co-polyesterpolycarbonate or amorphous co-polyesterpolyether or combination thereof. Additionally, uses for the low density foams are disclosed.
US11525044B2	Hard-coat-layer-forming composition and optical member The present invention provides a hard-coat-layer-forming composition whereby a hard coat layer having excellent scratch resistance and cracking resistance can be formed, and an optical member. The hard-coat-layer-forming composition is a composition used to form a hard coat layer on a plastic substrate, and includes: metal oxide particles; at least one type of component X selected from the group consisting of an organic silicon compound represented by a predetermined formula, a hydrolysate thereof, and a hydrolytic condensate thereof; and at least one type of component Y selected from the group consisting of an organic silicon compound represented by a predetermined formula, a hydrolysate thereof, and a hydrolytic condensate thereof, and a glycoluril crosslinking agent, a hydrolysate thereof, and a hydrolytic condensate thereof.
US11525043B2	High light transmittance photovoltaic encapsulating material The present disclosure relates to a high light transmittance photovoltaic encapsulating material, which is prepared by the following process: subjecting 100 mass parts of a photovoltaic encapsulating material matrix resin or a graft-modified matrix resin, 0.001 to 5 mass parts of an oxygen- or sulfur-containing compound, 0.01 to 10 mass parts of a reactive plasticize 0.01 to 1.5 mass parts of an initiator, 0.01 to 10 mass parts of an assistant cross-linker, 0.1 to 3.0 mass parts of a silane coupling agent, 0.1 to 0.4 mass parts of an ultraviolet light absorber, and 0.1 to 1.0 mass part of light stabilizer to pre-mixing, melt extrusion, film casting, cooling, slitting, and coiling. The light transmittance of the photovoltaic encapsulating material is improved, and the refractive indexes of glass/front-layer encapsulating material/cell match each other, thereby increasing the sunlight utilization ratio of a module, and optimizing the photoelectric conversion efficiency of the module.
US11525039B2	Organic-inorganic composite particles and method for producing same The present invention provides organic-inorganic composite particles of which the creep deformation is further suppressed; and a method for producing the same. Organic-inorganic composite particles 10 include a compound having a siloxane bond and has a particle diameter d0, and when a load is applied such that an amount of displacement Ds satisfies 0.08d0≤Ds≤0.15d0 and is held for 180 seconds, conditions of the following Formulae (1) and (2) are satisfied: (D180−Ds)/d0≤1% Formula(1); and (Dmax−Ds)/d0≤1% Formula (2), wherein d0 is an average particle diameter, D180 is an amount of displacement of the particle diameter after 180 seconds of application of the load, and Dmax is the maximum amount of displacement of the particle diameter during the 180 seconds.
US11525037B2	Tetracarboxylic dianhydride, polyimide precursor resin and solution thereof, and polyimide and solution thereof A tetracarboxylic dianhydride represented by the following general formula (1): [in the formula (1), R1, R2, and R3 each independently represent a hydrogen atom and the like, and n represents an integer of 0 to 12], wherein a ratio of a summed amount of a specific stereoisomer (A) and a specific stereoisomer (B) is 50% by mole or more relative to a total amount of stereoisomers based on three-dimensional configurations of two norbornane rings in the general formula (1), and a content ratio of the stereoisomer (A) is 30% by mole or more relative to the total amount of the stereoisomers.
US11525036B2	Chemical compositions with antimicrobial functionality Techniques regarding killing of a pathogen with one or more ionene compositions having antimicrobial functionality are provided. For example, one or more embodiments can comprise a method, which can comprise contacting a Mycobacterium tuberculosis microbe with a chemical compound. The chemical compound can comprise an ionene unit. Also, the ionene unit can comprise a cation distributed along a molecular backbone. The ionene unit can have antimicrobial functionality. The method can further comprise electrostatically disrupting a membrane of the Mycobacterium tuberculosis microbe in response to the contacting.
US11525033B2	Polymer-metal junction comprising PEEK-PEmEK copolymer compositions, in contact with a metal substrate The present invention generally relates a polymer-metal junction comprising PEEK-PEmEK copolymers compositions, in contact with a metal substrate, wherein the PEEK-PEmEK copolymer having RPEEK and RPEmEK repeat units in a molar ratio RPEEK/RPEmEK ranging from 95/5 to 45/55. The present invention also relates to shaped articles including the polymer-metal junction, and methods of making the polymer-metal junctions.
US11525030B2	Method for preparing biogenic guanidine complex, method for preparing polyethylene terephthalate (PET), and method for preparing poly (ethylene isophthalate-co-terephthalate) (PEIT) A method for preparing a biogenic guanidine complex, the method including: mixing dimethyl sulfoxide (DMSO) with water in a volume ratio thereof of 1:1 to yield a solvent DMSO-H2O; adding organic guanidine (G) and a compound MX2 in a molar ratio G/MX2=1:1 or 2:1 to the solvent DMSO-H2O, where the organic guanidine (G) is selected from arginine (Arg), guanidinoacetic acid (Gaa), creatine (Cra), creatinine (Cran), guanine (Gua), and agmatine (Agm); M represents Fe2+, Mg2+, or Zn2+; and X represents Cl−, CH3COO−, or CH3CH(OH)COO−; stirring the solvent DMSO-H2O containing the organic guanidine and the compound MX2; recycling the solvent DMSO-H2O through vacuum distillation and obtaining a solid; transferring the solid to a Buchner funnel, and washing the solid with deionized water and ethanol consecutively; and removing the deionized water and ethanol through vacuum filtration, and drying the solid. Biogenic guanidine complex can be used for production of Polyethylene terephthalate or Poly(ethylene isophthalate-co-terephthalate).
US11525029B2	Foam compositions Foam compositions are provided. The compositions are prepared from multi-functional acetoacetate esters and multi-functional amines or acrylates. The foam compositions can include one or more additives. The foam compositions can be used for home and commercial insulation, air sealing, sound proofing, structural improvement, and exterior roofing, among other applications. The foam compositions provide advantages of being isocyanate free and offer reduced exposure to isocyanate.
US11525027B2	Curable photochromic composition including a segmented polymer The present invention relates to a curable photochromic composition that includes: (a) a photochromic compound; and (b) a segmented polymer that includes active hydrogen groups, at least one first segment, and at least one second segment, in which, (i) each first segment independently includes a (meth)acrylic polymer segment, and (ii) each second segment independently includes at least one of, a polycarbonate segment, a polyester segment, a polyether segment, a polyurethane segment, and combinations of two or more thereof. The curable photochromic composition further includes (c) a curing agent having reactive functional groups that are reactive with the active hydrogen groups of the segmented polymer (a), in which the curing agent includes at least one of, a polyisocyanate, a polyisothiocyanate, and an aminoplast. The present invention also relates to photochromic articles that include at least one layer formed from the curable photochromic composition of the present invention.
US11525025B2	Block copolymers and uses thereof A styrenic block copolymer having one or more polymer blocks A and one or more polymer blocks B is disclosed, where “A” is a poly(vinylaromatic) block having a molecular weight of greater than 5 kg/mol. The “B” block has a molecular weight of more than 15 kg/mol, and comprises polymerized 1,3-diene units and vinylaromatic units, wherein the polymerized vinylaromatic units represent 5-40 wt. % of the overall weight of the block “B”. The polymerized 1,3-diene units comprise more than 80 wt. % of polymerized isoprene units in which 45-80 mol % are 1,4-isoprene addition units. The blocks “A” and “B” represent from >5 to <40 wt. %, and >33 to <95 wt. %, respectively, relative to the overall weight of the block copolymer. The polymers have physical properties that make them valuable, e.g., as vibration damping materials.
US11525024B2	Bio-based polymers from raw lignocellulosic biomass Disclosed herein is a method of making polymerizable bio-based monomers containing one phenolic hydroxyl group which has been derivatized to provide at least one polymerizable functional group which is an ethylenically unsaturated functional group (such as a [meth]acrylate group), where the precursors of the polymerizable bio-based monomers are derived from raw lignin-containing biomass. Also disclosed herein are bio-based copolymers prepared from such bio-based monomers and a co-monomer, and methods of making and using such bio-based copolymers. In particular, the bio-based copolymers can be used as pressure sensitive adhesives, binders, and polymer electrolytes.
US11525020B2	Processes to produce poly alpha-olefin trimers The present disclosure generally relates to processes to produce alpha-olefin oligomers and poly alpha-olefins. In an embodiment, a process to produce a poly alpha-olefin (PAO) includes introducing a first alpha-olefin and a first catalyst system comprising a metallocene compound into a continuous stirred tank reactor or a continuous tubular reactor under first reactor conditions to form a first reactor effluent. The alpha-olefin is introduced to the reactor at a flow rate of about 100 g/hr or more. The first reactor effluent includes PAO dimer comprising at least 96 mol % of vinylidene and 4 mol % or less of trisubstituted vinylene and disubstituted vinylene, based on total moles of vinylidene, trisubstituted vinylene, and disubstituted vinylene. The method includes introducing the first reactor effluent, a second alpha-olefin and a second catalyst composition comprising an acid catalyst into a second reactor under second reactor conditions to form a second reactor effluent comprising PAO trimer.
US11525019B2	Process for preparing acrylic emulsion resin A process for preparing an acrylic emulsion resin is provided by introducing specific monomers at a certain time during an emulsion polymerization process, dispersion stability and adhesion properties of the acrylic emulsion resin are improved, thereby providing an aqueous acrylic pressure-sensitive adhesive that not only has excellent initial adhesion but also has low viscosity and improved processability, and high adhesion holding power.
US11525016B2	Compositions comprising glucose and hemicellulose and their use Provided herein are purified hemicellulose compositions, sweetener compositions including purified hemicellulose compositions, as well as methods for making the same. Also provided are uses of the compositions.
US11525003B2	Anti-B7-H3 antibodies and diagnostic uses thereof Provided herein are B7-H3 antibodies, fragments of such antibodies, and compositions comprising the same. The antibodies, antibody fragments and compositions are useful in a number of analytical methods, including immunohistochemical and immunocytochemical detection and analysis of B7-H3. Also provided herein are isolated peptides and fusion proteins containing immunogenic determinants for said B7-H3 antibodies, animals immunized with the peptides and fusion proteins, isolated B cells obtained from the animals, and hybridomas made from the isolated B cells.
US11525001B2	Anti-CD8 antibodies and uses thereof Anti-CD8 antibodies, radiolabeled anti-CD8 antibodies, fluorescently labeled anti-CD8 antibodies and their use in imaging are provided herein. Included are methods of detecting the presence of CD8 proteins in a subject or sample.
US11525000B2	Anti-human VISTA antibodies and use thereof The invention provides antagonistic and agonistic anti-human VISTA antibodies and antibody fragments. These antagonist antibodies and antibody fragments may be used to inhibit or block VISTA's suppressive effects on T cell immunity and thereby promote T cell immunity. These agonist antibodies and antibody fragments may be used to potentiate or enhance or mimic VISTA's suppressive effects on T cell immunity and thereby suppress T cell immunity. These antagonist antibodies and antibody fragments are especially useful in the treatment of cancer and infectious conditions. These agonist antibodies and antibody fragments are especially useful in the treatment of autoimmunity, allergy, inflammatory conditions, GVHD, sepsis and transplant recipients. Screening assays for identifying these agonists are also provided.
US11524999B2	Fully humanized anti-platelet factor 4 antibodies that treat heparin-induced thrombocytopenia Provided herein are isolated antibodies or antibody fragments thereof that immunospecifically bind to platelet factor 4 (PF4). In some embodiments the isolated antibodies or antigen-binding fragments thereof comprise a light chain CDR and framework region comprising SEQ ID NO: 4 and a heavy chain CDR and framework region comprising SEQ ID NO: 10. Also provided herein are methods for treating heparin-induced thrombocytopenia (HIT) and methods for reducing the likelihood that subject will become afflicted with HIT. Further disclosed are uses of the isolated antibodies or antibody fragments in the treatment of HIT or the manufacture of compositions for the treatment of HIT.
US11524998B2	Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.
US11524997B2	Gremlin-1 inhibitor for the treatment of a bone fracture or bone defect The present invention relates to methods for the treatment of a bone fracture or bone defect. The invention discloses the effective use of an anti-gremlin-1 antibody to accelerate the healing and bridging of bone tissue in segmental gap defects; and demonstrates that inhibitors of gremlin-1 activity may provide improved therapies for treating or preventing fracture non-union.
US11524996B2	Method for producing refolded recombinant humanized ranibizumab The present invention relates to a novel cloning, expression and refolding process for preparing antibody fragments. More particularly, the present invention relates to a cloning, expression and refolding platform for preparing recombinant humanized (rHu) Ranibizumab.
US11524994B2	Antibodies to human respiratory syncytial virus protein F pre-fusion conformation and methods of use therefor The present disclosure is directed to antibodies binding to human respiratory syncytial virus F protein, including both neutralizing and non-neutralizing antibodies, and methods for use thereof.
US11524993B2	Neutralizing anti-influenza binding molecules and uses thereof Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
US11524991B2	PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof The present invention is directed to novel PD-1-targeted IL-15/Rα-Fc fusion proteins comprising an IL-15/IL-15Rα Fc-fusion protein and a PD-1 antigen binding domain. The PD-1-targeted IL-15/Rα-Fc fusion proteins can be administered to a patient to treat cancer.
US11524990B2	Methods for treating vascular eye disorders with ActRII antagonists Disclosed herein are compositions and methods for increasing visual acuity in patients in need thereof and for treating vascular disorders of the eye.
US11524986B2	Peptide-based inhibitors of growth hormone action and methods of use thereof Compositions and methods for the inhibiting human growth hormone (hGH), and treating or preventing hGH-mediated disorders, using a S1H peptide having the amino acid sequence of [SEQ ID NO: 1], or a variant thereof, are described.
US11524977B2	Ultrasound-assisted simulated digestion method of milk protein active peptide and application thereof in health foods An ultrasound-assisted simulated digestion method of a milk protein active peptide and an application thereof in health foods, pertaining to the technical field of intensive processing of dairy products and preparation of health foods. The method firstly employs ultrasonic pretreatment of casein and β-lactoglobulin, followed by enzymatic hydrolysis with a protease to prepare casein and ρ-lactoglobulin polypeptide, and traces the activity of the polypeptide by simulating gastrointestinal digestion, and then simulates absorption by intestinal epithelial cells with Caco-2 cells, to characterize a highly active milk protein polypeptide digested by the gastrointestinal tract and absorbed by the Caco-2 cells simulating absorption by the inner wall of the small intestine. The method has identified five such highly active milk protein polypeptides.
US11524975B2	Amphiphilic compound having dendronic hydrophobic group and application thereof The present invention relates to an amphiphilic compound having a dendronic hydrophobic group, a method for preparing the same, and a method for extraction, solubilization, stabilization, or crystallization of a membrane protein by using the same. The use of the compound according to the present invention leads to an excellent membrane protein solubilization effect and a stable storage of a membrane protein in an aqueous solution for a long time, and thus can be utilized for functional analysis and structural analysis of the membrane protein. Especially, the amphiphilic compound having a dendronic hydrophobic group showed very remarkable characteristics in the visualization of protein composites through an electronic microscope. The membrane protein structural and functional analysis is one of the fields of greatest interest in current biology and chemistry, and more than half of the new drugs that are currently being developed are targeted at membrane proteins, and thus the amphiphilic compound of the present invention can be applied to membrane protein structure studies closely related to the development of new drugs.
US11524970B2	Nitrogen-containing compound, electronic element, and electronic device Provided are a nitrogen-containing compound, an electronic element, and an electronic device, and relates to the technical field of organic materials. The nitrogen-containing compound is shown as formula I, and can reduce the working voltage of an electronic element, improve the efficiency of an OLED, and prolong the service life of an OLED.
US11524966B1	Carboxamides as ubiquitin-specific protease inhibitors The present disclosure relates to modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25, pharmaceutical compositions comprising the inhibitors, and methods of using the inhibitors. The modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25 can be useful in the treatment of cancers, among other ailments.
US11524960B2	Heterobicyclic inhibitors of MAT2A and methods of use for treating cancer The present disclosure provides for compounds according to Formula I or Formula II and their pharmaceutically acceptable salts, stereoisomers, and/or tautomers thereof. Also provided are pharmaceutical compositions and the compounds of formulae I and II for use in methods of treating cancers, via inhibition of MAT2A, including some cancers in which the gene encoding methylthioadenosine phosphorylase (MTAP) is deleted and/or not fully functioning.
US11524959B1	Indole and azaindole inhibitors of pad enzymes The present invention provides compounds of Formula (I) useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders, wherein each of Ring A, L, Q, R1, R2, R3, R4, R7, and R8 along with other variables are as defined herein.
US11524955B2	2,4-diamino-pyrimidine compounds and method for making and using the compounds Compounds within the scope of the present invention have a Formula 1 or a salt or produg thereof, where ring A is selected from cycloaliphatic; ring B is aryl; R1 is selected from (C1-C10)alkyl, (C3-C10)cycloalkyl, halo, aryl, and heteroaryl; and R2 and R3 are independently selected from hydrogen and (C1-C6)alkyl. Disclosed compounds may have an IRAK4 IC50 of from 0.003 μM to 3.7 μM; a TAK1 IC50 of from 0.008 μM to 132 μM; and/or an IRAK4/TAK1 selectivity of from 1 to 450. Particular compounds may have an IRAK4/TAK1 selectivity of from 100 to 500. Disclosed compositions may be formulated as pharmaceutical compositions. A method for using the compounds and/or compositions also are disclosed. The method may comprise administering to a subject an effective amount of a compound within the scope of the present invention, particularly to selectively inhibit IRAK 1 and/or IRAK4 over TAK1.
US11524950B2	Treatment of immune-related and inflammatory diseases Provided herein are methods of using compounds and compositions for modulating leukocytic activity, including activity of B cells and/or T cells monocytes, macrophages, and other lymphoid or myeloid-derived cell types, in immune-related diseases or inflammatory diseases. Pharmaceutical compositions and dosing regimens for use in the methods are also provided herein.
US11524949B2	Degraders and Degrons for targeted protein degradation Pharmaceutical Degraders and Degrons for use in therapeutic applications are described herein.
US11524944B2	2-phenylpyrimidine-4-carboxamides as AHR inhibitors The present invention covers 2-phenylpyrimidine-4-carboxamide compounds of general formula (I): (I) 5 in which X, Y, Z, R1, R2, R4, R5 and R6 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer or conditions with 10 dysregulated immune responses or other disorders associated with aberrant AHR signaling, as a sole agent or in combination with other active ingredients.
US11524943B1	Benzocarbonyl compounds Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.
US11524942B2	Metabolites of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4 yl}-phenoxy)-propyl]-diethyl-amine The present invention relates to metabolites of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl-amine. These metabolites may act as RAGE antagonists. These metabolites may also be useful in assays to measure the presence or amount of one or more metabolites of the parent compound in a sample.
US11524939B2	Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid Provided herein are solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid (Vadadustat, Code: AKB-6548, Compound 1), compositions comprising such solid forms, and methods of making and using thereof.
US11524938B2	Aromatic sulfonamide derivatives Substituted aromatic sulfonamides of formula (I) pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease.
US11524937B2	Indirubin derivatives, and uses thereof Indirubin is the major active anti-tumor component of a traditional Chinese herbal medicine used for treatment of chronic myelogenous leukemia (CML). Indirubin derivatives (IRDs) potently reduce the viabilities of various cancer cells and affect kinase activities. IRDs disclosed herein provide new therapeutics for cancer and conditions regulated by the kinase activities.
US11524930B2	Substituted aromatic compounds and related method for the treatment of fibrosis The present invention relates to compounds of: or a pharmaceutically acceptable salt thereof, wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4;R1 is H, F or OH;R2 is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4;R3 is H, F, OH or CH2Ph;R4 is H, F or OH;Q is 1) (CH2)mC(O)OH wherein m is 1 or 2, 2) CH(CH3)C(O)OH, 3) C(CH3)2C(O)OH, 4) CH(F)—C(O)OH, 5) CF2—C(O)OH, or 6) C(O)—C(O)OH; and compositions comprising the same and the method using the same for the prevention or treatment of various fibrotic diseases and conditions in subjects, including pulmonary fibrosis, liver fibrosis, skin fibrosis, renal fibrosis, pancreas fibrosis, systemic sclerosis, cardiac fibrosis or macular degeneration.
US11524926B2	Maximization of light olefins in FCC process The invention includes a fluid catalytic cracking process that comprises reacting a hydrocarbon feedstock under catalytic cracking conditions in the presence of a FCC catalyst and an additive, wherein the additive comprises a ZSM-5 molecular sieve having iron in the framework, wherein the process increases production of propylene compared to a process without using the additive. The invention also includes an additive for maximizing production of olefins, which comprises a ZSM-5 molecular sieve having iron in the framework.
US11524923B2	Dielectric ceramic composition and ceramic electronic components Provided is a dielectric ceramic composition including a first component and a second component, wherein the first component comprises an oxide of Ca of 0.00 mol % to 35.85 mol % an oxide of Sr of 0.00 mol % to 47.12 mol %, an oxide of Ba of 0.00 mol % to 51.22 mol %, an oxide of Ti of 0.00 mol % to 17.36 mol %, an oxide of Zr of 0.00 mol % to 17.36 mol %, an oxide of Sn of 0.00 mol % to 2.60 mol %, an oxide of Nb of 0.00 mol % to 35.32 mol %, an oxide of Ta of 0.00 mol % to 35.32 mol %, and an oxide of V of 0.00 mol % to 2.65 mol %, and the second component includes at least (a) an oxide of Mn of 0.005% by mass to 3.500% by mass and (b) an oxide of Cu and/or an oxide of Ru.
US11524920B2	Optical fiber coating die with reduced wetted length An optical fiber coating apparatus that provides increased gyre stability and reduced gyre strength, thereby providing a more reliable coating application process during fiber drawing includes a cone-only coating die having a conical entrance portion with a tapered wall angled at a half angle α, wherein 2°≤α≤25°, and a cone height L1 less than 2.2 mm, and a cylindrical portion having an inner diameter of d2, wherein 0.1 mm≤d2≤0.5 mm and a cylindrical height of L2, wherein 0.05 mm≤L2≤1.25 mm; a guide die having an optical fiber exit, the guide die disposed adjacent the cone-only coating die such that a wetted length (L5) between the optical fiber exit of the guide die and the entrance of the cone-only coating die is from 1 mm to 5 mm; and a holder for holding the cone-only coating die and the guide die in a fixed relationship defining a coating chamber between the guide die and the cone-only coating die, the coating chamber having an inner radius L6 from the optical fiber axis to an inner wall of the holder that is from 3 mm to 10 mm.
US11524917B2	Multiple tube burner for synthesizing porous material and apparatus for synthesizing porous material A multiple tube burner for synthesizing a porous material includes three or more glass tubes are arranged coaxially with one another, the glass tubes having a substantially circular shape on a cross section perpendicular to a longitudinal direction. Out of the three or more glass tubes, a first glass tube and a second glass tube that is arranged on an outer side of the first glass tube are connected with each other on a gas introducing side, and a thickness near a joint portion of the second glass tube connected with the first glass tube is thicker than a thickness of the second glass tube on the gas spouting side.
US11524905B2	Blend for odor control A method of providing sustained odor control in an extended sewer line is disclosed. The method includes measuring at least one parameter of the sewer line including average wastewater volume, flow rate, and retention time and administering a blended composition which includes an immediate release compound and an extended release compound into the sewer line to control concentration of an odorous compound therein. A method of facilitating sustained odor control in an extended sewer line is also disclosed. The method includes providing the blended composition including the immediate release compound and the extended release compound and instructing a user to administer the blended composition to the sewer line control concentration of the odorous compound therein. A system for providing sustained odor control in the extended sewer line including sensors to measure sewer line parameters and a controller to instruct administration of the blended composition is also disclosed.
US11524901B2	Method for efficiently separating magnesium and lithium from salt lake brine and simultaneously preparing high-purity magnesium oxide and battery-grade lithium carbonate This invention provides a method for efficiently separating magnesium and lithium from salt lake brine, and simultaneously preparing high-purity magnesium oxide and battery-grade lithium carbonate. The detailed processing steps are as follows: (1) adding urea into the brine to dissolve, (2) placing the solution into the reactor for hydrothermal reaction, the magnesium ion will precipitate and enter the solid phase; (3) filtering and drying the production to get the magnesium carbonate solid, while the lithium ion remains in the liquid phase; (4) after directly concentration and precipitation, the battery-grade lithium carbonate can be obtained, while the calcination of solid-phase product results in the high-purity magnesium oxide. In this method, urea is used as the precipitant to separate magnesium and lithium in salt lake without introducing any new metal ion, and the brine solution is not diluted. The solid product is white and fluffy powder, which is easy to filter and separate. The extraction rate of lithium is high than 94%, and the purity of MgO obtained by calcination is higher than 99.5%.
US11524899B2	System and method for removal of carbon from carbon dioxide Disclosed is a system and method related to removal of carbon from carbon dioxide via the use of plasma arc heating techniques. The method involves generating C atoms and H atoms from CxHy. The method involves generating graphite and H2 from the C atoms and H atoms, and extracting the graphite. The method involves quenching the H2 with CxHy. The method involves receiving, at a generator, the quenched the H2 and CYHy and generating electricity. The method involves generating a concentrated stream of H2 from the quenched H2 and CxHy. The method involves receiving CO2 and the concentrated stream of H2 and generating C, O, and H atoms. The method involves receiving the C, O, and H atoms and generating graphite, wherein the graphite is extracted. In the hydrocarbon CxHy: x is an integer 1, 2, 3, . . . , and y=2x+2.
US11524898B2	Formation of pores in atomically thin layers Atomically thin layers including pores, their method of manufacture, and their use are disclosed. In some embodiments, pores may be formed in an atomically thin layer by growing the atomically thin layer on exposed portions of a substrate that includes islands comprising a material that is different than the material of the substrate. In some embodiments, pores and/or defects may be formed in an atomically thin layer by employing growth conditions that promote the formation of defects and/or pores. In certain embodiments, pores and/or defects may be etched to enlarge their size.
US11524896B2	Aqueous hydrogen peroxide purification method and purification system A purification method for an aqueous hydrogen peroxide solution, includes passing the aqueous hydrogen peroxide solution through a first H-form strong cation exchange resin column 1, a salt-form strong anion exchange resin column 2 and a second H-form strong cation exchange resin column 3. An H-form strong cation exchange resin having crosslinking of 6% or less, an H-form strong cation exchange resin having crosslinking of 9% or more, or an H-form strong cation exchange resin produced by steps (a) and (b) is used as an H-form strong cation exchange resin packed in the second H-form strong cation exchange resin column 3: (a) copolymerizing a monovinyl aromatic monomer with a crosslinkable aromatic monomer having a non-polymerizable impurity content of 3% by weight or less therein using a predetermined amount of a specified radical polymerization initiator at a predetermined polymerization temperature to obtain a crosslinked copolymer; and (b) sulfonating the crosslinked copolymer.
US11524891B2	Membrane support for dual backplate transducers A microfabricated structure includes a perforated stator; a first isolation layer on a first surface of the perforated stator; a second isolation layer on a second surface of the perforated stator; a first membrane on the first isolation layer; a second membrane on the second isolation layer; and a pillar coupled between the first membrane and the second membrane, wherein the first isolation layer includes a first tapered edge portion having a common surface with the first membrane, wherein the second isolation layer includes a first tapered edge portion having a common surface with the second membrane, and wherein an endpoint of the first tapered edge portion of the first isolation layer is laterally offset with respect to an endpoint of the first tapered edge portion of the second isolation layer.
US11524889B2	Addressable display system for ICA monitoring and annunciation for certified applications running on a personal electronic device An addressable display system configured for use in a mounting adapter configured to mount a personal electronic device (PED) on an aircraft includes a transparent surface configured to overlay the display surface of a PED when the PED is mounted in the mounting adapter wherein the transparent surface includes a region that is uniformly coated with a coating layer that when activated with a select excitation wavelength is configured to emit visible light to annunciate a message indicating a problem with an image displayed on a PED display; a lighting source configured to provide light in at an excitation wavelength; a MEMS (microelectromechanical systems) scanner module that is controllable to write desired symbology for annunciation at different addressable locations on the transparent surface; and an imaging device configured to capture an image of the PED display for an integrity check of data displayed on the PED display.
US11524884B2	Beverage distribution system with ergonomic retention of drinking recipients, and process of operation thereof A beverage distribution system for preparation of espresso coffee and similar aromatic beverages, including a drinking recipient (1, 1′), for example of glass, cup, or similar type, a beverage discharge disposition (2) operatively associated with a beverage preparation device (3), whereby the beverage discharge disposition (2) is provided so that the beverage discharge flow impinges, along a direction opposite to the gravity force and with a given flow pressure, and a flow regulation mechanism (13) on the drinking recipient (1, 1′), whereby the drinking recipient (1, 1′) presents a recipient retention mechanism (17) provided so that the drinking recipients (1, 1′) can only be placed on the recipient placement support (22) in one or two previously defined angular extensions with relation to the beverage discharge disposition (2).
US11524879B2	Remote control system for a crane A handheld remote control for a crane includes a wireless transceiver, an input device, a display screen, and processing circuitry. The wireless transceiver is configured to wirelessly communicate with a controller of the crane. The input device is configured to receive a user input. The display screen is configured to display information regarding deployment of a stabilizer of the crane. The processing circuitry is configured to obtain the user input via the input device, and cause at least one stabilizer of the crane to deploy or retract based on the user input.
US11524878B2	First-order dynamic sliding mode variable structure-based bridge crane anti-swing method A bridge crane anti-swing method based on first-order dynamic sliding mode variable structure includes steps of: constructing a two-dimensional bridge crane system model and a crane system control model, respectively; performing differentiation on two sliding mode surfaces containing swing angle dynamic change and rope length dynamic change to obtain a crane position dynamic sliding surface s1 and a rope length dynamic sliding mode surface s2, respectively; combining a displacement x, a length l and a swing angle θ in the two-dimensional bridge crane system model with the crane position dynamic sliding surface s1 and rope length dynamic sliding mod surface s2 in the crane system control model to obtain a relationship among a horizontal traction force f1, an along-rope traction force f2, the displacement x, the length l and the swing angle θ.
US11524875B2	Elevator with linear motor An elevator includes at least one elevator shaft and at least one elevator car traveling in the elevator shaft. The elevator has at least one elevator motor including at least one linear stator located vertically along the elevator shaft and at least one mover located in connection with the elevator car and co-acting with the stator. The elevator includes a vertical stator beam supporting at least one stator, which stator beam has at least one side face carrying ferromagnetic poles of said stator spaced apart by a pitch. The mover includes at least one counter-face facing the side face(s) of the stator beam, in which electro-magnetic components of the mover are located.
US11524870B2	Method for operating a lift system and lift system designed for carrying out the method A method of operating an elevator system, for example operated by linear motors, wherein the elevator system includes a shaft system including at least one vertical elevator shaft, and a multiplicity of elevator cars which respectively have a plurality of functional components for carrying out different functions. The method provides that in a special operating mode of the elevator system, a first elevator car is assigned at least one auxiliary device, the auxiliary device providing a replacement function for at least one function of one of the functional components of the first elevator car, the corresponding function of a functional component of the first elevator car being replaced with the replacement function provided by the auxiliary device, and the elevator system continuing to be operated by using the replacement function provided. The invention furthermore relates to an elevator system configured for carrying out such a method.
US11524863B2	Spool with movable hub A spool has a first flange and a second flange. A barrel extends between the first flange and the second flange. A movable hub is located radially inward of the barrel. The barrel is axially wider than the movable hub and the movable hub is axially movable between a first operational position adjacent the first flange and a second operational position adjacent the second flange. The movable hub includes an axially-extending cantilevered detent arm forming a stop surface that limits axial movement of the movable hub toward one of the first flange and the second flange.
US11524860B2	Extraction assembly of a core from a log, converting line having said assembly and method for producing a coreless log Disclosed herein is an extraction assembly for producing coreless logs. The extraction assembly includes a rectilinear transporter (20) of a log (11) wound about a disintegrable core (12), and a gripping device (30) for a portion of the core (12) projecting from the log (11), wherein the rectilinear transporter (20) has a transverse transport direction with respect to a log advancement direction of the log (11) along the converting line (100), and has an alternating transport direction back and forth in opposite directions, and the rectilinear transporter (20) contains a first portion for being received within the converting line (100), and a second portion for being placed outside the converting line (100), in which the second portion is aligned with respect to the first portion along the transverse transport direction. Also disclosed herein are a converting line containing the extraction assembly, and methods for producing coreless logs.
US11524857B2	Adhesive bonding of tray for image forming apparatus An image forming apparatus includes a main body including an image forming unit to form an image on a recording medium and a tray that rotates between an open state and a closed state relative to the main body, the tray on which the recording medium is placed. The tray includes a first component located exterior to the image forming apparatus in the closed state and a second component in contact with the recording medium on the tray in the open state. The first or second component includes at least one groove portion which extends in a conveyance direction of the recording medium and the other includes at least one convex portion extending in the conveyance direction. The first and second components are bonded by adhering, with an adhesive, the at least one groove portion and the at least one convex portion put inside the at least one groove portion.
US11524856B2	Medium feeding device A medium feeding device is provided with a feeding section for feeding a medium and sensors for detecting the medium. The feeding section includes a feed roller and a separation roller, the sensors form a sensor line in which the plurality of sensors is aligned in a feeding direction of the medium to be fed, the two sensor lines are arranged in such a manner that the sensors overlap with each other in a width direction of the medium to be fed, and the sensor lines are so configured as to extend, in the feeding direction, from an upstream region upstream of a nip point where the feed roller and the separation roller make contact with each other, a nip region including the nip point, and to a downstream region downstream of the nip point.
US11524853B2	Device for separating printing paper sheets and printer A device for separating printing paper sheets comprises a base part and an obstruction element. The base part defines a printing paper accommodating cavity. A deforming mechanism is provided to make sure a middle part of the printing paper sheets can be arched and two edges can get close to the bottom of the printing paper accommodating cavity. The obstruction element is arranged with a middle access portion in cooperation with the deforming mechanism, and on two sides of the middle access portion is arranged with blocking portions through which only one printing paper sheet can pass at a time. The device for separating printing paper sheets makes more than one printing paper sheet that may be transmitted at a time during the transmission of the printing paper sheets. A printer achieves smooth transmission of printing paper sheets and alleviates problems such as downtime and failure of the printer.
US11524852B2	Pull-in apparatus, image forming apparatus, sheet accommodating apparatus, and draw-out unit A pull-in apparatus configured to pull in a unit toward a predetermined position in an apparatus body includes an arm member, a restriction member, a first action portion and a second action portion. The restriction member is movable between a lock position at which the restriction member restricts movement of the arm member in a first direction and a lock-release position at which the restriction member allows the movement of the arm member in the first direction. Movement of the restriction member from the lock position toward the lock-release position is restricted in a state in which the arm member is at a stand-by position, and is allowed in a state in which the arm member has been moved from the stand-by position in a second direction.
US11524845B2	Flat sorter over at least two levels A sorting system and a method for sorting piece goods provide for conveying the piece goods to be sorted on a delivery level to a delivery point and delivering them there into or onto a receiving device moving on a collection level receiving the piece goods. The collection level is disposed below the delivery level. The receiving device travels over an individually determined route on the collection level.
US11524843B2	Rubbish bin lock assembly A rubbish bin lock assembly includes a rubbish bin that has a lid is hingedly to a top end of the rubbish bin for opening and closing the rubbish bin. A plurality of receivers is each attached to the rubbish bin. A rod is included which has a sequence of bends thereon thereby facilitating the rod to be positioned around the lid. A plurality of engagements is each integrated into the rod and each of the engagements releasably engages a respective one of the receivers when the lid is in a closed position. In this way the lid is inhibited from being opened by animals from opening the lid. Additionally, each of the engagements disengages the respective receiver when the rod is urged into an unlocked position thereby facilitating the lid to be opened.
US11524842B2	Incentivized multi-stream recycling system with fill level, volume, weight, counters, shredder, compactor, consumer identification, display and liquid drainage system An embodiment relates to a trash collection device comprising a trash receptacle with a unique identification and an opening to receive a class of trash; an identification scanner for recognizing a user; a trash item counter; a fill level sensor; a display configured to interact with the user; a compactor; a solar panel configured to charge a battery; a data communicator configured to communicate date to a cloud storage; a processor configured to generate incentive for the user; wherein the trash collection device is configured to be modular and configurable to connect with another similar trash collection device to enable to collect additional trash class and is configured to interact with each other through a common software. The device, method and system are further used to generate recycling analytics by using the stored data to provide incentives to users and to facilitate planning of downstream operations.
US11524833B2	Container and method of forming a container An insulating container can be configured to retain a volume of liquid, and include a canister having a first inner wall having a first end having an opening extending into an internal reservoir, and a second outer wall forming an outer shell. The opening can be sealed by a spout adapter, the spout adapter having a spout channel extending between the internal reservoir and a spout opening, smaller than the opening of the canister. The spout opening may be sealed with a cap having a magnetic top surface, and the spout adapter may be further removably coupled to a lid that may be used as a cup into which a volume of the liquid can be poured.
US11524830B2	Microwave heating construct Various blanks are provided for forming sleeves, containers, and other constructs for heating, browning, and/or crisping of a food item in a microwave oven, and for holding and/or transporting the food item after heating. The various blanks, sleeves, containers, and other constructs may include a removable portion defined by one or more lines of disruption that enable the removable portion to be separated from the remainder of the blank, sleeve, container, or other construct.
US11524828B2	Tamper evident bag A tamper evident bag has front and rear panels connected together along opposite first and second side edge margins and a bottom edge margins that define a bag interior and a first bag opening therebetween. The first and second side edge margins include first and second peripheral side edges. The front and rear panels each have a tear line with a first end and a second end, the first and second ends being adjacent to and spaced apart from the first peripheral side edge. The first and second ends of each tear line being spaced part. The tear lines extend over the front and rear panels but remain spaced from the second side edge margin. Each tear line defines a respective tear out section on the front and rear panels. The tear out sections are joined along the first side edge margin and are configured to be removed to create a second bag opening.
US11524824B2	Child resistant container with activator buttons A child resistant container having a three-point activator system is provided. The container comprises a tray, a carton or other enclosure and a plurality of buttons that must be simultaneously depressed or otherwise activated to remove the tray out of the carton. The buttons are positioned so as to require an adult hand to operate.
US11524821B2	Dispensing closure for a container A dispensing closure (40) includes a body (54) for being located at the opening of a container (44) defining a central axis (30) and having a pour spout (72). The body (54) including a crushable seal (200) surrounding the pour spout (72), and the body (54) including a lateral projection (210) extending therefrom. The closure (40) includes a closing element (56) for being removably attached to the body (54) and having a lateral projection (220) extending therefrom. The closing element (56) and the body (54) have a closed condition in which the crushable seal (200) seals between the closing element (56) and the body (54) and the lateral projections (210, 220) are confronting to inhibit separation of the closing element (56) away from the body (54) along the central axis (30).
US11524819B2	Leak-proof press-fit sealed container An apparatus is disclosed. The apparatus includes a tray having a base connected to a plurality of sidewalls each of which extends away from the base and terminates at a rim, said tray defining a volume with an opening circumscribed by said rim, said rim comprising a press-fit sealing feature; a ring-shaped lid comprising a complimentary press-fit sealing feature configured to mate with said press-fit sealing feature; a product disposed in said volume wherein said product surface comprises at least one contour; and a flexible film, said flexible film spans said opening and adheres to the at least one contour of the product, and said flexible film is secured to said tray between said press-fit sealing feature of the rim and said complimentary press-fit sealing feature of the ring-shaped lid.
US11524818B2	Container and related methods A one-piece molded container comprising a lid and a container body is provided. The container body and lid are connected by a living hinge. The container body has interior protrusions extending from a bottom portion in an interior of the container body to limit nesting of the containers. The container body has a recess on a bottom portion on an exterior portion of the container and a dual-prong lid-locking mechanism, the lid-locking mechanism including a first prong, a second prong being a tamper-evident tearaway portion, and a protrusion extending downwardly from an interior portion of the lid.
US11524816B2	Plastics shipping bag A plastics shipping bag includes a closure flap which projects beyond the front wall, can be folded over the outer face of the front wall, and comprises a passage opening, which is configured and designed for the passage of a handle loop or handle of the front wall and/or rear wall, wherein the closure flap comprises at least one fastening means between the opening edge of the rear wall and the passage opening, which fastening means is configured and designed to close the opening end once the closure flap has been folded over onto the outer face of the front wall. The plastics shipping bag can be used for shipping foods, such as chilled foods.
US11524812B2	Blow-molded unitary structure with enhanced strength A blow-molded unitary structure includes a panel having first and second panel walls and a generally hollow interior between the first and second panel walls. The structure also includes a plurality of depressions, or at least one ridge, or both the depressions and ridge to enhance the strength of the structure. The plurality of depressions is monolithically formed with the panel, recessing from the second panel wall toward the first panel wall. A depression has a side wall composed of first and second segments. Cross-sectional-wise, the first and second segments have different widths and thus collectively forms a step between the first and second segments. A ridge is also monolithically formed with the panel and includes a section, at which the width of the ridge varies along the height direction of the ridge.
US11524809B2	Working station with a lifting mechanism for a packaging machine The invention relates to a working station, in particular to a deep-drawing station, to a molding station, to a sealing station, to a cutting station or to a punching station, for a packaging machine, comprising a rack supported on the ground; a work unit comprising an upper part and a lower part; and a lifting mechanism which is carried by the rack and by which the lower part of the work unit can be raised and lowered relative to the rack to perform a lower stroke, wherein the lifting mechanism has a drive that comprises at least one shaft extending in a transverse direction; a drive motor engaging at the shaft for rotating the shaft; and at least one gear which is coupled at an input side to the shaft, at which the lower part is supported at an output side, and which converts a rotation of the shaft into the lower stroke of the lower part.
US11524802B2	Binding machine A rebar binding machine comprises a curl guide that causes a wire to curl, a torsion part including a torsion shaft for twisting the curled wire, and a pair of grips that can be grasped by an operator. The grips are provided to the two axial sides of the torsion shaft as viewed from the operator side when the operator grasps the grips to perform an operation, and it is possible to change the height of the grips in the axial direction of the torsion shaft.
US11524794B2	Illuminated aircraft passenger cabin gasper An illuminated aircraft passenger cabin gasper comprises an air outlet for outputting a flow of air into an aircraft passenger cabin and an air guide, movably arranged within the air outlet for adjusting the flow of air that includes a light guide. The gasper also includes at least one light source, arranged adjacent to the light guide for coupling light into the light guide. The light guide has a light output surface for coupling light out of the light guide into the aircraft passenger cabin.
US11524790B2	Enhanced pitot tube power management system and method A system, power management system and method are disclosed. The power management system includes a pitot tube, one or more heating elements disposed in the pitot tube, and one or more power switches, wherein each power switch of the one or more power switches is coupled to a respective heating element and configured to energize or de-energize the respective heating element in response to a control signal. The power management system also includes a temperature detector coupled to the pitot tube and configured to determine a temperature of the pitot tube, and a processor complex coupled to the one or more power switches and the temperature detector and configured to output the control signal to energize or de-energize at least one of the heating elements through a respective at least one of the respective one or more power switches in response to at least the determined temperature of the pitot tube or a detection of a fault.
US11524788B2	Floor fixing assembly with clamping split pin A floor fixing assembly for releasable fixing of a leg of a frame to a vehicle floor comprises at least one retaining peg which can be fixed to the vehicle floor. The floor fixing assembly furthermore comprises a frame fixing element, which is configured to be connected to the leg of the frame and comprises at least one receiving space for receiving the retaining peg. A clamping device is configured to be introduced into the receiving space of the frame fixing element in order to connect the frame fixing element to the retaining peg by form fit.
US11524786B2	Deployable armrest with pawl and ratchet height adjustment mechanism The present disclosure provides a deployable and height adjustable armrest assembly for use with, for example, an aircraft pilot seat. The assembly includes an armrest positioned atop a rack comprising a plurality of detents each corresponding to a deployed armrest position. A lever carries a pawl that travels along one edge of the rack which locates in a selected one of the plurality of detents to lock the armrest in one of its deployed positions. The armrest is configured to be raised manually to deploy and adjust the armrest upward. The lever is configured to be actuated manually to disengage the pawl from its engagement in one of the detents to lower or return the armrest to its stowed positions. The armrest is particularly advantageous in close quarters such as a flight deck, or where a stowed armrest can be used to expand the width of the seat bottom.
US11524780B2	Fan powered folding wing bicycle apparatus A fan powered folding wing bicycle apparatus for novelty and transportation includes a frame and a rear wheel coupled between a pair of lower horizontal tubes. A stem is pivotably coupled within a head tube. A handle bar is coupled to the stem. A pair of forks is coupled to the stem and a front wheel is coupled to the pair of forks. A pair of engine straps is coupled between a pair of top horizontal tubes. A duct is coupled to the pair of engine straps and a turbine is coupled within the duct. A seat is coupled to the duct. A battery is in operational communication with the turbine. A pair of wings is pivotably coupled to the pair of top horizontal tubes.
US11524779B2	Aircraft for take off and landing on water and on land The invention relates to an aircraft for takeoff and landing on water or on land. The aircraft comprises a fuselage and a spring-mounted landing gear. Landing gear wheels are mountable on the landing gear for takeoff and landing on land. Furthermore, the aircraft comprises a floating device coupleable to the landing gear of the aircraft via a connecting device. The floating device is configured such that the hydrostatic lifting force of the floating device is greater than the maximum takeoff weight of the aircraft.
US11524778B2	VTOL aircraft A VTOL aircraft has fixed wings and a rotor blade system for providing lift in active and passive modes thereof. Operation of the rotor blade system may be switched between the active mode in which the rotor blade system is driven by a power system of the aircraft and the passive mode in which the rotor blade system is not driven by the power system, the rotor blade system being configurable to provide lift in the passive mode during forward flight of the aircraft. The rotor blade system provides lift in the passive mode, allowing the fixed wings to be shorter than in the case where the rotor system provides lift during vertical take-off and landing but otherwise has no function, thus providing aircraft which is lighter, more compact and more efficient than similar aircraft of the prior art.
US11524777B2	Individual blade control system for rotorcraft A blade pitch control system includes a plurality of serially stacked swashplate assemblies, each having concentric, ring-shaped inner and outer sections, an associated output pitch link coupled to its outer section and an associated input pitch link coupled to its inner section. The inner and outer sections of each swashplate assembly includes pass through holes to accommodate input pitch links and output pitch links of adjacent ones of the stacked swashplate assemblies. The system also includes a plurality of actuators, each coupled to a respective input pitch link of a respective one of the stacked swashplate assemblies. A central static mast accommodates a rotor drive shaft and the stacked swashplate assemblies are configured to slide axially, parallel to a long axis of the static mast.
US11524776B2	Rotor control mechanism A compact and unobtrusive rotor control mechanism is presented that provides collective and cyclic pitch change to both rotors of a coaxial rotor system as well as a differential collective pitch change to one or both rotors simultaneously.
US11524774B2	Automobile engine The present invention provides a power device generating greater propelling force and finds that traditional power devices do not include all propelling forces based on the fundamental core propelling force source problem. External pressure is guided to the traditional power devices since the inner speed is higher the outer speed, power consumption for overcoming fluid resistance is high, and mutual contradiction results are obtained. The unique difference between the present invention and general common sense lies in opposite fluid pressure directions; inner fluid channels and outer fluid channels with higher flow speeds are formed to generate pressure differences which guides the fluid pressure to the outside and serve as propelling force, and thus the present invention creatively finds three propelling force sources, two lifting force or propelling force sources of helicopters or airplanes driven by propellers and two propelling force sources for sufficient burning of fuel in combustion chambers of engines.
US11524771B2	Landing gear drive system The invention provides a drive system for rotating a wheel of an aircraft landing gear. The drive system includes a motor operable to rotate a drive pinion, and a driven gear adapted to be mounted to the wheel. The drive system has a first configuration in which the drive pinion is capable of meshing with the driven gear to permit the motor to drive the driven gear and a second configuration in which the drive pinion is not capable of meshing with the driven gear. The drive system includes a linear positioning actuator for moving the drive pinion relative to the driven gear. The positioning actuator has a first end and a second end, the first end having a pivotal connection with a pivot axis spaced at a fixed distance from an axis of rotation of the driven gear, and the second end having a pivotal connection with a pivot axis spaced at a fixed distance from an axis of rotation of the drive pinion.
US11524770B2	Active laminar flow control plenum panel arrangements and installation methods A panel for an active laminar flow control arrangement may comprise a longitudinal wall and one or more division walls extending from the longitudinal wall and extending between the first end and the second end. The panel may be coupled to a nacelle outer skin via a plurality of adhesive fasteners pre-installed onto an inner surface of the outer skin and onto stiffeners and/or stringers associated with the outer skin.
US11524769B1	Wireless cabin control panels A wireless aircraft cabin control panel is disclosed. In embodiments, the wireless aircraft cabin control panel includes a user interface device disposed on a first surface of a bulkhead of an aircraft cabin. In embodiments, the user interface includes a display device, a user input device, wireless communication circuitry, and a controller. The controller may be configured to: generate control signals configured to cause the wireless communication circuitry to transmit wireless control signals to wireless communication circuitry of a control unit disposed on a second surface of the bulkhead; receive power via wireless charging signals received from the wireless communication circuitry of the control unit; distribute power from the wireless charging signals to the display device; extract data signals encoded within the wireless charging signals; and cause the display device to display at least one of an indicator or an image in response to the extracted data signals.
US11524767B2	Methods and systems for flight control configured for use in an electric aircraft A system for flight control configured for use in an electric aircraft includes a sensor configured to capture an input datum. The system includes an inertial measurement unit (IMU) and configured to detect an aircraft angle and an aircraft angle rate. The system includes a flight controller including an outer loop controller configured to receive the input datum from the sensor, receive the aircraft angle from the IMU, and generate a rate setpoint as a function of the input datum. The system includes an inner loop controller configured to receive the aircraft angle rate, receive the rate setpoint from the outer loop controller, and generate a moment datum as a function of the rate setpoint. The system includes a mixer configured to receive the moment datum, perform a torque allocation as a function of the moment datum, and generate a motor command datum as a function of the torque allocation.
US11524766B2	Single motor single actuator rotorcraft An unmanned rotorcraft includes an airframe, rotor blades that are coupled to the airframe for rotation therewith, a propulsion unit having a propeller, and an actuator that is coupled to the airframe and adapted to temporarily reorient the propulsion unit such that an axis of the propeller moves out of alignment with an axis of the rotor blades. Rotation of the propeller causes counter-rotation of the airframe and rotor blades. The rotor blades and blades of the propeller are adapted to deploy from collapsed positions when flight of the rotorcraft is initiated. A method of operation by the rotorcraft includes, when it is determined that a current heading does not correspond to a determined flight path, causing the actuator to temporarily reorient the propulsion unit in accordance with an angular orientation of the actuator relative to the current heading.
US11524760B2	Variable-lift ability device comprising an anti-stratification diffuser A variable-liftability device includes a pressurized hermetically sealed chamber accepting a gas of density lower than the density of the air; a mixer arranged at least partially inside the hermetically sealed chamber and configured to introduce air into the hermetically sealed chamber.
US11524755B2	Second-stage diving regulator A second stage diving regulator with separated stages that allows changing a position of connection of a LP hose for low pressure supplied from a first stage of the regulator, characterized in that around connected bodies there is a rotating ring with a valve seat and a valve terminated with a thread to which a low pressure LP coming from the first stage of the machine is connected horizontally. The rotation of the rotary ring is ensured at least in the range of 180 degrees from the starting position, through all the intermediate angles downwards towards the cylinder, up to a horizontal position opposite to the starting position, the side of the body.
US11524754B2	Light guides with low refractive coating to be used in water The invention provides a light guide element comprising a light guide and a layer element, wherein the light guide comprises a light guide face and wherein the layer element comprises an optical layer, wherein said optical layer is in contact with at least part of the light guide face, wherein the optical layer has a first index of refraction (n1) smaller than the refractive index of seawater, wherein the light guide comprises a UV radiation transmissive light guide material.
US11524752B2	Mounting assembly for watercraft An assembly for a watercraft according to an example of the present disclosure includes, among other things, a flotation device including an elongated slot and a mount that has first and second flanges extending outwardly from a bracket body. The first flange is configured to be mechanically attached to a frame, and the second flange is slideably received in the slot to secure the flotation device. A method of assembly for a watercraft is also disclosed.
US11524751B2	Lateral displacement surf system and method of use The present disclosure generally pertains to a lateral displacement surf system and methods of laterally displacing a watercraft to generate wake. The lateral displacement system includes at least one pair of foils configured to be extended from a hull on a first side of the watercraft at a level of approximately the waterline. Upon forward movement of the watercraft with extended foils, the watercraft is rotated about its vertical axis toward the first side and generates waves sufficient for the conduction watersport activities on a second side of the watercraft. In some instances, foils are built into the hull and extended from this position, while in other instances the foils are attached to the hull using attachment structures. Rotation of the foils about an axis of rotation approximately perpendicular to a longitudinal axis of the watercraft alters the angle of attack of the foils relative to the waterline.
US11524740B2	Transportation device having multiple axes of rotation and auto-balance based drive control Various embodiments of transportation devices that have at least two axes of rotation and employ ride balance based drive control are disclosed. One embodiment is a scooter type device with a platform structure movable in fore-aft. The drive motor may be provided at the platform section or drive wheel or be otherwise located. Other embodiments include inline wheeled board embodiments. Yet other embodiments include those utilizing a continuous track. The continuous track embodiments may have two drive motors, among other features.
US11524738B2	Saddle-ridden vehicle A motorcycle includes a tail lamp, a rear covering, rear end components which are a license plate and a license lamp, a rear stay, and a sensor. The tail lamp emits light toward the rear side. The rear covering is provided with the tail lamp. The rear end components are disposed more rearward than the rear covering. The rear stay extends at least rearward from a connecting portion connected to the rear covering and supports the rear end components. The sensor senses an object rearward is at least partially received in an internal space that is formed either in the rear covering or in the rear stay.
US11524735B2	Work vehicle A work vehicle includes a plurality of traveling devices for driving traveling, a plurality of articulated link mechanisms having at least two or more joints and supporting the plurality of traveling devices to a vehicle body, with allowing the plurality of traveling devices to be elevated/lowered independently of each other, a driving mechanism capable of changing respective postures of the plurality of articulated link mechanisms independently of each other, and a plurality of turning mechanisms configured to support the respective plurality of the articulated link mechanisms, with allowing the link mechanisms to be orientation-changeable about a vertical axis.
US11524730B2	Track assemblies for terrain going vehicles and method for repairing the tracks A track assembly for a terrain going vehicles having tires, the track assembly having at least two traction bars. The traction bars each having a body that is dimensioned to extend over the width of a tire and guide plates extending from the body so that they can be set to reach over the edge of the tire and to the sides of the tires and ears at each end of each traction bar, extending crosswise on relation to the length of the traction bar and on both sides of the body of the traction bar, the ears having each at least one hole. There is at least one link having a link body with a length and one connecting hole at each opposite end of the link body, and pins set to run through a pair of one hole of the link body and at least one hole of a ear of the traction bar in order to form a chain, wherein the pins are locked in relation to the holes of the ears so that rotation of the pins in the holes is prevented.
US11524729B2	Spoiler for a pickup truck bed A removable spoiler or vehicle stabilizing apparatus for a pickup truck having a truck bed is provided. The spoiler comprises a spoiler shell constructed and arranged to fit securely on the truck bed, an interior spoiler frame, at least one mounting support configured to securely support the spoiler on the truck bed, and a plurality of spoiler securement and lifting elements. The spoiler may easily be installed or removed from the truck even while the truck is hitched to a travel trailer, camper trailer or the like. The spoiler may be installed or removed with any suitable device, such as a crane, jack, jack stands, cherry picker, auto cherry picker, travel trailer tongue-mounted lift/crane, lifts, roll on/off platform or the like. The spoiler may also be used as a multipurpose device, and may provide a golf cart enclosure, and may further comprise at least one utility shelf.
US11524728B2	Cabin assembly A vehicle includes a frame, a series of tractive assemblies coupled to the frame, a cabin, and a mount. The mount includes a boss coupled to the cabin, a first bracket pivotably coupled to the boss, a second bracket coupled to the frame, and a first isolator and a second isolator extending between the first bracket and the second bracket and coupling the first bracket to the second bracket.
US11524726B2	Body structure for automobiles The rear frame includes an inclined part that is inclined inward in, a vehicle width direction in going rearward and a horizontal part that extends rearward from a rear end of the inclined part. A rear part of the side sill includes a first enlarged width portion that increases in width inwardly in the vehicle width direction via a bent portion. A front part of the rear frame inclined part includes a second enlarged width portion that increases in width outwardly in the vehicle width direction. A rear end of the first enlarged width portion and a front end of the second enlarged width portion are connected. An inner wall in the vehicle width direction of the first enlarged width portion and an inner wall in the vehicle width direction of the inclined part are linearly continuous in plan view.
US11524723B2	Subframe for a vehicle A subframe for a vehicle, which comprises a first and second longitudinal member, wherein the longitudinal members extend in a longitudinal direction (x) and are relatively offset in a transverse direction (y) of the subframe, a transverse front member connectable to the first and second longitudinal member at a front section of the subframe, a transverse rear member connectable to the first and second longitudinal member at a rear section of the subframe.
US11524720B2	Crane with wheels having variable camber angle A crane for lifting and transporting loads includes a base frame for transferring the loads of the crane onto a support surface by a plurality of wheels. The wheels are capable of rotating relative to the base frame so as to change the camber angle of the wheels.
US11524712B1	Equipment transporter Various devices and techniques related to equipment transporters are generally described. In some examples, an equipment transporter may comprise a first set of wheels rotatable around an axis of rotation and a body coupled to and rotatably supported by the first set of wheels such that the body is rotatable around the axis of rotation of the first set of wheels. The body may comprise a platform having an upper surface and extending in a first direction. The platform may have a distal end and a proximal end. The body may comprise a tab member located at the distal end of the platform and extending upward from the upper surface. In some examples, the tab member may comprise a pulling face having a first width. In some examples, the body may further comprise a riser located at the proximal end of the platform and extending upward from the upper surface.
US11524711B2	Method for mounting a rail monitoring element A method of mounting a rail monitoring member/element at a mounting location of a rail for rail traffic, in particular on a railway track, is disclosed. The rail monitoring member includes a strain sensor member with a carrier on which a strain gauge, being an optical fiber with a fiber Bragg grating, is fixed. The method steps include: determination of the temperature of the rail and/or rail monitoring member at the mounting location; checking whether the determined temperature is within a predefined temperature interval; providing heating or cooling application to the rail and/or rail monitoring member at the mounting location, if the determined temperature is not within the predefined temperature interval; positioning and adhesively fixing of the carrier of the rail monitoring member at the mounting location. The method can be carried out easily and allows reliable and accurate monitoring of the rail using a strain sensor member.
US11524705B2	Vehicle control system In a vehicle control system (1, 101), a control unit (15) is configured to execute a stop process by which the vehicle is parked in a prescribed stop position located within a permitted distance when it is detected that the control unit or the driver has become incapable of properly maintaining a traveling state of the vehicle, and, in executing the stop process, the control unit computes an agreement between an object (X) contained in the map information based on an estimated position of the vehicle and an object (Y) on the road detected by an external environment recognition device (6), the permitted distance being smaller when the agreement is below a prescribed agreement threshold than when the agreement is equal to or above the agreement threshold.
US11524704B2	Vehicle travel control method and travel control device The travel control device, when determining that the traffic congestion is occurred in the other lane, detects, behind another vehicle in the other lane, an approach space; determines whether the approach space meets a predetermined condition; when determining that the approach space meets the predetermined condition, sets the target posture of the own vehicle at the target position behind the other vehicle in the other lane based on the shape of the approach space; and generates a target traveling trajectory from a current position of the own vehicle to the target position. The travel control device controls the motion of the own vehicle so that the own vehicle tracks the target traveling trajectory.
US11524701B2	Methods and systems of predicting road agent behavior using voxel grids A method includes encapsulating a current state of a road portion into a voxel grid, a first dimension of the voxel grid being associated with a first spatial dimension of the road portion, a second dimension of the voxel grid being associated with a second spatial dimension of the road portion, and a third dimension of the voxel grid comprising a plurality of feature layers, wherein each feature layer is associated with a feature of the road portion. The voxel grid may be input into a trained neural network and a future state of the road portion may be predicted based on an output of the neural network.
US11524698B2	Information processing apparatus and information processing method Section information of a traveling route is provided appropriately to a driver.Traveling route information and traffic information relating to the traveling route are acquired, and on the basis of the information, a driver intervention requiring section and an automatic driving available section of the traveling route are displayed on a reach prediction time axis from a current point on an instrument panel, a tablet, or the like. For example, the driver intervention requiring section includes a manual driving section, a takeover section from automatic driving to manual driving, and a cautious traveling section from the automatic driving.
US11524696B2	Method for determining the values of parameters A method for determining the values of parameters for a controller of a vehicle, wherein respective error measures are calculated for different sets of values and a set of values is selected based on the error measures.
US11524694B2	Vehicle control apparatus, vehicle, vehicle control method, and non-transitory computer-readable storage medium A vehicle control apparatus that comprises a first control unit and a second control unit each configured to perform travel control of a vehicle, a first communication line configured to connect the first control unit and the second control unit, a second communication line configured to connect the first control unit and an operation unit configured to operate based on a control signal transmitted from one of the first control unit and the second control unit, and a third communication line configured to connect the operation unit and the second control unit. The vehicle control apparatus further comprises a fourth communication line configured to connect the first control unit and the operation unit.
US11524692B2	Ridesharing and autonomous vehicle systems with mitigation of ride-related phobias A ride-share system of other vehicle system employs a profile database having a plurality of user phobia profiles for potential customers. Each of the user phobia profiles identifies one or more respective phobia groups pertaining to a respective user, wherein each phobia group associates a plurality of driving-related phobias which share at least one trigger condition or at least one countermeasure. A vehicle controller is coupled to the profile database which determines a default itinerary for a trip to a destination specified by one of the users. The vehicle controller evaluates the default itinerary for potential interaction with a respective phobia group identified by the phobia profile of the one of the users. The vehicle controller implements an alternate itinerary that mitigates the potential interaction.
US11524691B2	System and method for controlling an interior environmental condition in a vehicle A system and method are described for controlling a vehicle interior environmental condition. A biometric sensor senses a biometric condition of a vehicle seat occupant and generates a sensed biometric condition value. A controller receives the sensed biometric condition value, a sensed interior environmental condition value, and a sensed exterior environmental condition value. Each of multiple exterior environmental condition values has an associated biometric condition value defined as optimal for the vehicle occupant. The controller determines the optimal biometric condition value associated with the sensed exterior environmental condition value, compares the optimal biometric condition value to the sensed biometric condition value, and in response to a difference between the optimal biometric condition value and the sensed biometric condition value, generates a control signal to control an actuator to control the controllable interior environmental condition to reduce the difference between sensed biometric condition value and the optimal biometric condition value.
US11524684B2	Vehicle control device for an adaptive variable suspension A vehicle control device includes: a control portion that makes, of a plurality of shock absorbers included in a vehicle, a first damping force of at least one shock absorber that is located on a first direction side on which acceleration acts in a longitudinal direction of the vehicle larger than a second damping force of at least one shock absorber of the plurality of shock absorbers that is located on a second direction side opposite to the first direction in the longitudinal direction of the vehicle before acceleration acting on the vehicle is detected by an acceleration sensor due to acceleration or deceleration of the vehicle.
US11524683B2	Vehicles, methods, and devices for vehicle retarder control and display Industrial vehicles that include a speed sensor configured to generate a speed sensor signal, a payload sensor configured to generate a payload sensor signal, an inclination sensor configured to generate an inclination sensor signal, a wheel motor connected to a wheel of the industrial vehicle, and a controller. The wheel motor includes an electric retarder device for applying a retardation force to the wheel. The controller is configured to receive the speed sensor signal, receive the payload sensor signal, receive the inclination sensor signal, determine a required retardation force for the industrial vehicle based on the payload sensor signal and the inclination sensor signal, determine an available retardation force for the industrial vehicle based on the speed sensor signal, and generate an output indicating the required retardation force for the industrial vehicle relative to the available retardation force for the industrial vehicle.
US11524680B2	Control device and control method for controlling behavior of motorcycle The present invention provides a control system and a control method capable of appropriately supporting driving of a motorcycle by a rider. The control system includes a tracking target vehicle identifying unit that identifies a tracking target vehicle of adaptive cruise operation, a vehicle position information acquiring unit that acquires information on the relative position of the tracking target vehicle with respect to the motorcycle during traveling, a control amount setting unit that sets a control amount in the adaptive cruise operation, and an execution unit that causes the motorcycle to execute the adaptive cruise operation, and further includes a lane position information acquiring unit that acquires information on the relative position of a lane boundary with respect to the motorcycle during traveling, in which the tracking target vehicle identifying unit identifies the tracking target vehicle, based on the position information acquired by the lane position information acquiring unit.
US11524679B2	Adaptive cruise control with user-defined lateral acceleration threshold A vehicle includes an engine, an accelerator pedal, and a controller. The controller is programmed to command torque to the engine based on a set speed of adaptive cruise control and is programmed to, in response to the adaptive cruise control being active, a measured lateral acceleration of the vehicle exceeding a user-defined lateral acceleration threshold during a road curve, and the accelerator pedal being released, reduce a speed of the vehicle below the set speed until the measured lateral acceleration is less than the lateral acceleration threshold.
US11524678B2	Energy-optimized forced regeneration of a particle filter of a hybrid vehicle Various embodiments include a control system for the regeneration of a particle filter in an exhaust gas flow of an internal combustion engine of a hybrid vehicle including an electric machine comprising: a particle filter; a temperature sensor measuring an actual temperature of the filter; a first heat source upstream of the filter; and a controller. The controller is programmed to: determine a temperature difference between a setpoint temperature for regeneration of the particle filter and the actual temperature of the particle filter; calculate a power output difference to be applied based at least in part on the temperature difference; and control the first heat source using the power output difference.
US11524676B2	System and method for two step motor for electric vehicle (EV) truck and commercial vehicle applications In at least one embodiment, a system for a class 7 or 8 vehicle is provided. The system includes a first motor, a second motor, and a controller. The first motor is configured to generate torque for the vehicle. The second motor is configured to drive an engine of the vehicle such that the vehicle meets a desired speed as set forth by a driver. The controller is configured to drive at least one of the first motor and the second motor and to receive a first signal indicative of a speed of the vehicle. The controller is further configured to deactivate the first motor if the speed of the vehicle is greater than a predetermined speed limit.
US11524674B2	Electrified vehicle on-board generator power limit arbitration An electrified vehicle may include an engine, an electric machine selectively coupled to the engine, a high-voltage traction battery electrically coupled to the electric machine and configured to selectively propel the electrified vehicle, an on-board generator including an inverter electrically coupled to the high-voltage traction battery and configured to convert direct current input to alternating current output, power outlets configured to receive power from the inverter of the on-board generator, a user interface, and a controller programmed to control the engine, the electric machine, and the high-voltage traction battery to provide power to on-board generator and to control the inverter to limit the power output by the inverter to the power outlets to one of a user-specified power limit based on input from the user interface, a powertrain power limit associated with the engine, the electric machine, and the high-voltage traction battery, and an inverter hardware power limit.
US11524673B2	Hybrid vehicle There is provided a hybrid vehicle that enables user to be more appropriately notified of a control effect by performing a drive support control. A hybrid vehicle includes an engine; a motor; a battery; map information; and a control device programmed to set a drive route from a current location to a destination, to create a drive support plan that assigns one of drive modes including a CD mode and a CS mode to each of drive sections of the drive route, and to perform drive support control that causes the hybrid vehicle to be driven along the drive support plan. The control device accumulates control effect obtained by performing the drive support control and notifies the control effect when the hybrid vehicle reaches the destination. The control device deletes the control effect when the predetermined deletion condition is satisfied.
US11524672B2	Control techniques for controlling electric hybrid retrofitted vehicles An electric motor drive retrofit system (EMDRS) comprises a power system, an energy storage system (ESS), a cooling system, a vehicle control unit (VCU), and a user interface device (UID). A non-hybrid combustion engine drive vehicle with tight space constraints is retrofittable with the EMDRS to provide hybrid drive functionality. EMDRS includes a motor generator unit (MGU) coupled to a motor control unit that transfers charge between MGU and ESS. During retrofit, the MGU is coupled between a transmission and an internal combustion engine (ICE) of the vehicle without extending a powertrain length by more than five inches. VCU does not interfere with any pre-existing vehicle electronics. The VCU controls the EMDRS to add torque (discharging ESS) or to remove torque (charging the ESS) based on a selected operating mode and vehicle sensor information (for example, brake and throttle pressure). Operating modes are selected by driver via the UID.
US11524670B2	Control device for vehicle and control method for vehicle The controller forms a control device for a vehicle with which torque generated in an engine and a motor generator is transmissible to a continuously variable transmission in accordance with a driving force request from a driver. The controller includes an engine controller forming a motor control unit adapted to control an output of the motor generator in accordance with the driving force request, and a transmission controller forming a transmission capacity control unit adapted to control a transmitted torque capacity of the continuously variable transmission, and, in a case where motor assistance is performed and when stability of the transmitted torque capacity of the continuously variable transmission is detected, performs the motor assistance.
US11524669B2	Brake controller A brake controller according to the present disclosure that changes an effect correlation value correlating to an effect of braking in a first braking system provided in a vehicle in accordance with a vehicle condition of the vehicle includes a control part generating a braking force by at least one of the first braking system and a second braking system different from the first braking system in a case where the vehicle condition is a first condition based on a braking distribution ratio different from that in a case where the vehicle condition is a second condition and a setting part setting the effect correlation values so as to be different from each other in the case where the vehicle condition is the first condition and in the case where the vehicle condition is the second condition.
US11524668B2	Method for operating a brake system of a motor vehicle, brake system, motor vehicle A method is provided for operating a motor vehicle brake system that includes an actuatable brake master cylinder, a hydraulic brake booster, and at least one brake circuit that has at least one hydraulically actuatable wheel brake and at least one hydraulic-pressure generator driven by electric motor. The method includes monitoring a state of actuation of the brake master cylinder is monitored, and, upon detecting a maximum state of actuation, activating the hydraulic-pressure generator to increase the hydraulic pressure adjusted by the brake master cylinder in the brake circuit.
US11524667B2	Brake systems integrated into vehicle corner modules and methods of use thereof A Vehicle Corner Module (VCM) based brake system, which includes a brake actuator, adapted to regulate the rotation rate of the wheel assembled to the VCM, a fluid-based brake power source, fluidly connected to the brake actuator and adapted to provide pressurized brake fluid for operating the brake actuator, and a brake-control-circuit, functionally associated with the brake actuator and with the brake power source, and adapted to provide functional inputs to the brake actuator based on a target rotation rate profile desired for a wheel mounted on the VCM. All mechanical components of the VCM-based brake system are disposed within the VCM. The VCM-based brake system and the vehicle platform are not in fluid communication with each other.
US11524665B2	Method for initializing an electronically slip-controllable power braking system after a startup and electronically slip-controllable power braking system A method for initializing an electronically slip-controllable power braking system after a startup and an electronically slip-controllable power braking system. Power braking systems are equipped with a pressure generator for conveying pressure medium in a pressure medium circuit. The pressure generator includes a plunger unit made up of a plunger cylinder, a plunger piston, and a plunger work chamber enclosed by plunger cylinder and plunger piston. A characteristic, using which an actuation of the plunger piston is carried out by the motor during the initialization of the power braking system, is selected by the electronic control unit as a function of a piece of information present about the position of plunger piston at the start of the initialization and implemented by corresponding electronic activation of the motor.
US11524662B2	Trailer leveling assemblies and method Systems and methods for manipulating the pitch and/or tilt of a trailer relative to a supporting surface. A trailer leveling system includes one or more telescopically adjustable support assemblies that are constructed to be pivotably connected to a frame of a trailer. Each support assembly includes a post that is pivotably connected to a trailer frame. A rack is formed along at least one side of the post. A tube slideably cooperates with the post and supports a pawl that cooperates with the rack to allow translation of the tube relative to the post in a first direction and selectively prevent translation of the tube relative to the post in the opposing direction.
US11524660B2	Tractor trailer roof heater apparatus A tractor trailer roof heater apparatus for preventing snow and ice accumulation includes a reservoir configured to hold heater oil within an inner cavity and configured to be coupled to a tractor trailer. A heater is coupled to a bottom side of the reservoir within the inner cavity and is configured to heat the heater oil. A pump is coupled to a top side of the reservoir and has a draw tube extending through a pump aperture into the inner cavity to draw the heater oil from the reservoir and push it through an outlet aperture through an oil tube. The oil tube is configured to be coupled within a roof of the tractor trailer to carry hot heater oil from the pump and then return the heater oil to the reservoir. A power supply is coupled to the pump and a thermostat is coupled to the reservoir.
US11524659B2	Cleaning device A cleaning device according to an embodiment is a cleaning device that cleans a light transmission member provided on a camera. The cleaning device includes a filamentary member configured to contact the light transmission member and a rotation member configured to rotate the filamentary member such that the filamentary member moves along the surface of the light transmission member with the filamentary member in contact with the light transmission member.
US11524653B1	Seat belt mounting structure A seat belt mounting structure includes a reel mounting reinforcement configured to connect a quarter inner panel, a roof center rail, and a roof rear rail; a C-pillar reinforcement formed to extend toward the quarter inner panel behind a C-pillar; and a seat belt reel mounted on the reel mounting reinforcement toward the roof center rail, the reel mounting reinforcement toward the quarter inner panel, and the C-pillar reinforcement. The seat belt mounting structure is arranged to reinforce a portion in which a seat belt is mounted, while having a reduced number of parts for anchoring the seat belt, and efficiently distributing a mounting load of the seat belt.
US11524651B2	Airbag cover The invention relates to a cover for closing a mouth of a receptacle holding an airbag with at least one airbag flap, wherein the cover has at least one breakaway line at the edge of the airbag flap(s) in order to enable the unfolding of the airbag, and wherein the airbag flap(s) is/are connected via a hinge element to a flap support wall in a molded manner, which is in contact with the inner surface of the receptacle wall in particular in a secured manner, wherein the flap support wall runs around the inner surface of the receptacle wall such that at least the four corners of the receptacle near the airbag flap(s) are covered.
US11524650B2	Head portion protection airbag device A head portion protection airbag device includes: an airbag, formed into a folded body being folded such that a lower edge side in an unfolded state approaches an upper edge side, wrapped with an unfoldment preventing tape material and attached to the upper edge side of the window, assembled with a twisting restriction member, which is configured to prevent twisting of the folded body, on an upper edge side of the airbag, and attached to the upper edge side of the window as a bag attachment body. A plurality of attachment piece portions, which are attached to a body side of the vehicle, are arranged side by side on the upper edge side of the airbag. The bag attachment body is wrapped with the tape material in a state where the twisting restriction member is assembled to the upper edge side of the airbag in the folded body.
US11524649B2	Vehicle seat A vehicle seat includes: a seat cushion in which a front panel extends between front parts of right and left side frames and a front rod extends between the front parts of the right and left side frames at a position rearward of the front panel in a longitudinal direction of a vehicle; a cushion airbag device mounted in a front part of the seat cushion and configured to inflate and deploy a cushion airbag when a frontal collision of the vehicle occurs; and a bag support fixed to the front rod, the cushion airbag being fixed to the bag support at a position rearward of the front rod in the longitudinal direction of the vehicle.
US11524640B2	Power supply apparatus A power supply apparatus includes a battery pack for an electric vehicle, and an interface unit that couples the battery pack and a plurality of electrical devices. The interface unit includes a branch connector provided with a coupling unit and a plurality of fuses. The coupling unit allows coupling wires to join. Each of the coupling wires is coupled to a corresponding one of electrical devices. Each of the plurality of fuses is disposed in a corresponding one of coupling wires. The interface unit also includes a battery pack connector that is able to be coupled to the branch connector. In a state in which the branch connector is coupled to the battery pack connector, the power supply apparatus is configured to be able to supply electric power from the battery pack to each of the plurality of electrical devices via the coupling unit.
US11524638B2	Enhanced communication system for vehicle hazard lights A system for implementing strobing of existing vehicle hazard lights including an interface to a vehicle wiring harness configured to receive input to an existing vehicle flasher module, and a strobing circuit that responds to an activation signal from the vehicle wiring harness that is indicative of a hazard flasher deployment event by producing an electrical output through the interface to the vehicle wiring harness that causes a strobing of existing vehicle hazard lamps.
US11524637B2	Vibration reduction device having acoustic meta structure A vibration reduction device having an acoustic meta structure mounted to a vehicle body and configured to block a structure-borne noise transmitted through the vehicle body may include a plurality of unit structures arranged at a predetermined interval therebetween, wherein each of the unit structures includes frame mounted to the vehicle body and configured to separate a predetermined space into a predetermined number of separate sections formed by walls of the frame; and a vibrator formed at a corner portion of each of the separate sections and each of which has a natural frequency to block a vibration transmitted from the vehicle body through the frame.
US11524636B2	Internally damped crossbar assembly having a slip plate damper A crossbar system for facilitating isolation of a sensor assembly from external vibrations of a support structure. The crossbar system comprises first and second crossbar assemblies and a payload mount, Each of the first and second crossbar assemblies comprises a crossbar segment and a slip plate damper. Each crossbar segment comprises a payload mount interface at a first end of the crossbar assembly and a first support structure interface at a second end of the crossbar assembly. Each slip plate damper is disposed about the crossbar segment and is slidably coupled to the crossbar segment to constrain movement in two lateral degrees of freedom and to facilitate movement in a longitudinal degree of freedom, Each slip plate damper comprises a second support structure interface at the second end of the crossbar assembly. The payload mount is coupled to the payload mount interfaces of the first and second crossbar assemblies.
US11524634B1	Switch mount housing for a utility task vehicle A housing assembly for mounting at least one electric component in a vehicle is provided as a three-dimensional form having an internal volume, a general material wall thickness, a top wall, a side wall, and a front wall surface presenting the at least one mounted electrical component to an operator in the vehicle, the form mountable at one side to a first installation point on a substantially vertical utility task vehicle (UTV) dashboard cover surface through an opening in the top wall and, and an elongated bracket fixed at one end to the inside wall of the side wall of the three-dimensional form, and at a second bracket end extending out from the side wall and below the three dimensional form mounted to a second installation point on the UTV dashboard.
US11524633B2	Vehicle accessories A bumper assembly is provided for a vehicle having a frame. The bumper assembly includes a winch cradle defining a cradle mounting aperture corresponding to a first frame aperture of the frame. A bumper member is configured to at least partially surround the winch cradle and extend laterally from the winch cradle across a portion of the vehicle. The bumper member defines a bumper mounting aperture corresponding to a second frame aperture. The winch cradle is configured to couple to the vehicle frame independent of the bumper member and the bumper member is configured to couple to the vehicle frame independent of the winch cradle.
US11524627B2	Adaptive interaction system with other road users A system and method for operating an automated vehicle. A sensor is configured to monitor an ORU (other road user) external to the automated vehicle thereby identifying the ORU with respect to the automated vehicle. A processor determines a state of the ORU and a context of the ORU and communicates a message to the ORU based on the determined state of the ORU and the context of the ORU.
US11524625B2	Adaptive vehicle headlight Example adaptive vehicle headlights are disclosed. An example system includes a photodetector, an illumination source configured to generate first light during a first operating mode, a spatial light modulator (SLM), and a dichroic filter optically coupled to the illumination source and to the SLM, wherein the dichroic filter is configured to direct the first light to the SLM, and the SLM is configured to direct second light to the dichroic filter during a second operating mode, wherein the dichroic filter is configured to direct the second light having a first color to the photodetector, and direct the first light during the first operating mode.
US11524622B1	Bracket for mounting light to steering arm A light mount for mounting a light to a steering arm on an axle may include a bracket designed to attach to the steering arm, wherein the bracket and, thus, the light pod rotate with rotation of the steering arm. The bracket may include a mounting frame, wherein a first edge of the mounting frame is concavely curved and wherein a plurality of mounting orifices extend through the mounting frame; and a mounting plate extending substantially perpendicularly from an upper edge of the mounting frame, wherein the mounting plate has a mounting orifice extending therethrough, the mounting orifice being sized to accommodate a fastener extending from a light pod.
US11524620B2	Tie down strap assembly including a plurality of anchor points A tie down strap assembly includes a strap and first and second hook assemblies disposed at respective opposing ends of the strap. The strap is formed of an elastic material. The strap defines a plurality of bores arranged along a length of the strap. Each of the first and second hook assemblies includes an engaging portion and a hook portion extending from the engaging portion. The engaging portion includes first and second sides. The engaging portion defines an opening extending through the first and second sides. The first side includes a mouth defining an aperture to receive a portion of the strap therethrough. The second side includes a boss configured to securely engage one bore of the plurality of bores of the strap. The hook portion is detachably couplable to the engaging portion of the other one of the first and second hook assemblies to interlock the first and second hook assemblies together.
US11524619B2	Tie-down loop assembly A tie-down loop assembly is configured to attach to a mounting surface and includes a mounting bracket, a biasing member, and a loop-isolator assembly. The mounting bracket has at least one carrier feature that has a carrier articulation axis. The loop-isolator assembly includes a loop having a substantially straight portion with a loop articulation axis and an isolator coupled to the loop straight portion. The isolator has a contact element and a loop-isolator articulation axis located coincidentally with the carrier articulation axis. When an articulation force is applied to the loop-isolator assembly, it causes the loop-isolator assembly to articulate relative to the mounting bracket, while the isolator contact element slippingly engages the biasing member movable portion. The engagement applies a biasing force to the contact element causing resistance to articulate the loop-isolator assembly relative to the bracket.
US11524614B2	Insert for integration into trim layer and providing conditioning An insert comprising: (a) a cover layer; (b) a spacer layer located below the cover layer; (c) a connection material that is adapted to extend between and connect the cover layer to a trim layer so that the insert is fixed to the trim layer.
US11524613B2	Ventilated seat with low pressure zone induced airflow A method of controlling a seat cooling cycle in a vehicle seat includes determining whether a vehicle cooling system is operating. If the vehicle cooling system is operating, then executing a seat cooling cycle such that portions of an occupant-facing surface of the vehicle seat are urged outwardly to create high contact zones between the occupant and the portions of the vehicle seat that have been urged outwardly, and such that areas of reduced occupant contact are defined between adjacent ones of the portions of the occupant-facing surface that are urged outwardly, wherein the areas of reduced occupant contact define low pressure zones that facilitate the flow of air between the vehicle seat and the occupant within the low pressure zones.
US11524611B2	Seat reclining device Proposed is a seat reclining device having a mobile flange that includes: a gear unit having an internal gear; a collar provided at a center of the gear unit; and a flange part connecting the collar and the gear unit to each other, and that is configured such that a radial cross-section of the flange part circumferentially repeatedly changes.
US11524610B2	Vehicle seat system In a vehicle seat system, lowering of a seat cushion further toward a vehicle lower side than a lowerable limit value corresponding to a recline angle of a seatback is restricted by a control device in cases in which the physical build of an occupant is smaller than a predetermined value. This enables a reduction in the ability to restrain the body of the occupant using a webbing to be suppressed.
US11524608B1	Moving seats in a vehicle to enhance occupant protection The disclosure provides for a system. The system may include a rotational control system configured to rotate a seat of a vehicle, and one or more computing devices. The one or more computing devices may have one or more processors that are configured to determine that an impact is imminent at a location on the vehicle along a collision axis. A most favorable orientation may be determined by the one or more processors based on the determined location and collision axis. Using the rotational control system, the one or more processors may rotate the seat of the vehicle to the most favorable orientation in order to reduce risks of serious injury to a passenger in the seat caused by the imminent impact. A translational control system may be used by the one or more processors to translate the seat of the vehicle to a position relative to the determined location.
US11524606B2	Vehicle floor structure A floor structure for a vehicle includes: a center floor; a plurality of longitudinal members attachably disposed on a top surface of the center floor; a plurality of seat rails disposed in the plurality of longitudinal members, respectively; and a battery assembly arranged under the center floor.
US11524605B2	Vehicle seat bottom stopper A vehicle seat includes a seat cushion supported on a frame. The seat cushion is removable from the frame to allow access an area beneath the seat. A handle is formed on a projecting portion of the seat cushion to facilitate grasping the seat cushion and to allow the seat cushion to be removed from the frame. A seat stopper is provided for preventing the projecting portion from contacting directly against a console or other surrounding part of the vehicle.
US11524603B2	Prompting method of bicycle information, a device, a server, and a user terminal A bicycle information prompting method, a device, a server, and a user terminal are disclosed. The method comprises obtaining current power information of a target bicycle and sending the target bicycle to a user terminal associated with the target bicycle according to the current power information, so that the user terminal displays prompt information associated with the target bicycle.
US11524602B2	Charge control device and charge control method A charge control device includes: a voltage generator which receives an input voltage and generates an output voltage; a power feeding circuit which supplies the output voltage to a terminal via a voltage supply line; and a control circuit. The control circuit is configured to make the power feeding circuit supply the output voltage when a value of the input voltage or the output voltage is equal to or higher than a first threshold value; electrically cut off the supply of the output voltage by the power feeding circuit when the value of the input voltage or the output voltage is less than the first threshold value; and resume the supply of the output voltage by the power feeding circuit when the value of the input voltage or the output voltage returns to be equal to or higher than the first threshold value.
US11524595B2	Electric transport device charging and cleaning station A method and system for providing an electric transport device charging and cleaning station is described. In one embodiment, a method for providing an electric transport device to a user includes receiving a request from a user for an electric transport device. The method also includes preparing the electric transport device for deployment, including cleaning and/or charging the electric transport device. The method further includes deploying the prepared electric transport device to the user.
US11524587B2	Vehicle with lift gate and power unit therefor The vehicle can have an engine and a moveable lift gate, a power unit driving the movement of the lift gate, the power unit including an electric motor and a capacitor pack, the capacitor pack being connected for powering the electrical motor, and being connectable to a DC alternator source of the engine.
US11524583B2	Plasma-based high-speed power transmission system A system for electrically connecting a vehicle to track electrodes, the system comprising vehicle electrodes configured to be electrically connected with a respective one of the track electrodes; actuators operatively connecting the vehicle electrodes to a structure of the vehicle for displacement of the vehicle electrodes relative to the structure of the vehicle, the actuators operable to vary distances between the vehicle electrodes and the track electrodes; sensors operatively mounted to one of the vehicle or track electrodes, the sensors detecting variations in the distances; and a controller operatively connected to the actuators for actuating the actuators as a function of the variations in the distances detected by the sensors.
US11524574B2	Axle drive An axle drive for a vehicle comprising at least one drivable vehicle axle oriented transversely to a longitudinal direction of the vehicle, said axle drive comprising an electric motor; a drive shaft that extends in parallel with the longitudinal direction between a first end and a second end and that is configured to receive drive power from the electric motor at an input section and to output said drive power at least partly to the vehicle axle via a bevel gear arranged at the first end; and a brake, in particular a parking brake, comprising a brake disk that is arranged at a brake section of the drive shaft, wherein the electric motor is arranged coaxially to the drive shaft and the input section of the drive shaft is arranged between the brake disk and the first end with respect to the longitudinal direction.
US11524573B2	Fuel storage device A fuel storage device includes a fuel tank, a circulation passage, a canister, a vapor passage, and an adjuster. The fuel tank is configured to store fuel. The circulation passage fluidly connects the fuel tank and a vicinity of a fuel supply port. The canister is configured to recover gas generated in the fuel tank. The vapor passage fluidly connects the fuel tank and the canister. The adjuster is configured to adjust a circulation flow rate of the gas flowing through the circulation passage in supply of the fuel, using a negative pressure.
US11524572B2	Pressurized gas tank for a motor vehicle A pressurized gas tank for a motor vehicle includes a cylindrical axially extending housing with two end pieces axially connected thereto connected together by one or more tie rods configured for axial transmission of tensile force. The tie rods include an axially continuous through-channel configured to be connected to a vehicle cooling system including a circulating liquid coolant to cool the pressurized gas at least during refueling of the pressurized gas tank.
US11524566B2	P3 hybrid transfer case A transfer case having, a transmission mount, an input shaft received through the transmission mount, an electric propulsion motor, a transfer case portion and a transmission portion. The transfer case portion has a transfer case portion input, a first transfer case portion output, a second transfer case portion output, and a power transfer mechanism, the first transfer case portion output being drivingly coupled to the transfer case input portion, the power transfer mechanism drivingly coupling the second transfer case portion output to the first transfer case output portion. the transmission portion has a first coupling, which is selectively operable for drivingly connecting the input shaft to the transfer case portion input, and a second coupling that is selectively operable for drivingly connecting a rotor of the electric propulsion motor to the transfer case portion input.
US11524558B2	Vehicle window, glass structure and adjustment method thereof A glass structure includes a glass body; a modulating unit coupled to the glass body to modulate optical characteristics of the glass structure; an interaction unit coupled to the glass body to provide an adjusting signal indicating an execution of adjusting the optical characteristics of the glass structure; and a control unit coupled to the modulating unit and the interaction unit respectively, the control unit being configured to receive the adjusting signal from the interaction unit and to control the modulating unit to modulate the optical characteristics of a target region of the glass structure in response to the adjusting signal. The interaction unit and the modulating unit are isolated from each other by a filling material having a transmittance equal to or greater than about 50%, a relative permittivity equal to or less than about 10, and a thickness equal to or greater than about 50 μm.
US11524557B2	Vehicle antiglare system and method and vehicle comprising antiglare system An antiglare system and method and a vehicle comprising the antiglare system. The antiglare system comprises a light transmittance adjustment plate, which includes at least one light transmittance adjustment portion, which in turn includes at least one first light transmittance adjustment region. The antiglare method comprises: capturing, from one side of a light transmittance adjustment plate, an image in a direction facing the light transmittance adjustment plate; determining a bright region in the image, and acquiring a position of the bright region in the image; determining, according to the position of the bright region, a first light transmittance adjustment region in the light transmittance adjustment plate; and if a bright region is present, adjusting light transmittance of the first light transmittance adjustment region. The antiglare system dynamically adjusts, according to different situations, light transmittance at different regions in a light transmittance adjustment plate, thereby adaptively adjusting light conditions.
US11524556B2	Light-reducing devices and methods of use Light-reducing devices that can be removably attached to a window or other panel through which light is able to pass, and methods of using such devices. Such a light-reducing device includes a tinted flexible transparent sheet and a microsuction tape adhered to the tinted flexible transparent sheet. The microsuction tape has a surface with micrometer-sized cavities that create a vacuum when the surface is pressed against a window. At least the surface of the tape is formed of a material that is sufficiently pliable and elastic so that each of the cavities forms a seal against the window and individual vacuums created between the surface and the window releasably secure the light-reducing device to the window when subjected to only the weight of the light-reducing device, but the light-reducing device can be peeled from the window.
US11524548B2	Air distribution arrangement with inflatable pipes for an air conditioning unit An air distribution arrangement for an air conditioning unit is provided. The air distribution arrangement includes a main body coupled to a housing of the air conditioning unit, and provided with a distribution chamber fluidically connected to at least one air transport conduit formed within the housing of the air conditioning unit, and a plurality of distribution pipes connected to the main body and configured to be connected to respective air outlets for distributing air within a cabin of a vehicle. Each of the distribution pipes is flexible and at least partially inflatable due to an air flow within it.
US11524547B2	Vehicle heating, ventilation, and air conditioning system An HVAC assembly for a vehicle. The HVAC assembly has an HVAC case with a rear blower and an evaporator. A rear blower scroll directs airflow generated by the rear blower to a lower portion of the evaporator. An airflow conduit is configured to direct airflow generated by a front blower to an upper portion of the evaporator. An airflow divider separates airflow generated by the rear blower from airflow generated by the front blower. The airflow divider divides the HVAC case into an upper area above the divider and a lower area below the divider. A defrost outlet and a front face outlet are at the upper area of the HVAC case above the divider. A front foot outlet and a rear airflow outlet are at the lower area of the HVAC case below the divider.
US11524545B2	Switching valve for an air spring arrangement and an air spring arrangement A switching valve for an air spring arrangement of a motor vehicle, which switching valve has a valve housing arrangement which, in the installed state, is arranged between a first air volume and a second air volume. A valve closing member arrangement is actuatable by an actuator is provided such that the valve closing member arrangement, in a first position, fluidically connects the first air volume to the second air volume and, in a second position, fluidically separates the first air volume from the second air volume. The valve closing member arrangement is designed as a rotary slide arrangement. A rotary slide member with first openings is provided between two valve closing bodies, wherein, in the first position, the first openings correspond with second openings of the valve closing body such that a fluidic connection can be produced between the first and the second air volume.
US11524544B2	Spring-absorber system with variable spring rate A spring-absorber system for a wheel suspension of a motor vehicle includes a suspension spring with a spring constant kT and an absorber filled with a fluid and mounted in parallel to the suspension spring. The spring-absorber system also includes at least two additional spring modules via which a total spring constant kG of the spring-absorber system can be varied.
US11524537B2	Vehicle communication system for sharing real-time articulated vehicle positions A vehicle, hitch, and articulating trailer include vehicle to vehicle and infrastructure communications and vehicle computing systems, which have a controller coupled to and/or including one or more of a dynamics measurement unit, a transceiver, and a position sensor, among other components. The controller(s) are configured to, in response to detecting positions of trailer corners from the position sensor, generate vehicle and trailer relative orientation and navigation data including location, velocity, and orientation, utilizing vehicle and trailer electronic polyhedrons articulating about a hitch point and representing the combination vehicle and trailer predicted path and envelopes. In response to detected trailer movement relative to the hitch point, the generated articulated polyhedrons are generated with the navigation data, which includes the location, speed, and orientation, which are in turn communicated to nearby vehicles and roadway infrastructure. Initial trailer vertices may be generated with wireless and mobile devices to generate the trailer polyhedron.
US11524536B2	Apparatuses, systems, and methods for determining and verifying operational states of fifth wheels Apparatuses, systems, and methods for determining and verifying operational states of fifth wheels. Certain methods for determining the operational state of the fifth wheel may include sensing, with at least one sensor, magnetic flux caused by a magnet on a movable component movable to lock the fifth wheel to a kingpin of a towed vehicle and determining an end position of the movable component based on the magnetic flux. The end position of the movable component is then compared to a threshold position and an operational state of the fifth wheel is determined based on the comparison of the end position of the movable component to the threshold position.
US11524534B2	Methods and apparatus for a load-sensing hitch utilizing a system of strain gauges Methods and apparatus are disclosed for a load-sensing hitch utilizing a system of strain gauges. An example apparatus includes a hitch including a first support including a first end, a second end, and a mid-portion located between the first end and the second end, the mid-portion having a cross-sectional area smaller than the cross-sectional area of the first end or the cross-sectional area of the second end, a strain gauge located at the mid-portion of the first support, a frame attachment to couple the hitch to a frame of a vehicle, the support coupled to the frame attachment, and a load manager to determine a load condition based on sensor data from the strain gauge.
US11524533B2	Apparatus and method for estimating tire resonance frequency An apparatus for estimating a tire resonance frequency may include a sensor for detecting rotation of a tone wheel; and a signal processor for calculating the detected rotation to produce a corrected wheel speed, filtering the corrected wheel speed in a predetermined manner to produce a filtered wheel speed from which engine noise is removed, and estimating a resonance frequency of a tire using the filtered wheel speed.
US11524528B2	Pneumatic tire In a pneumatic tire, a sipe includes an edge on a leading side and an edge on a trailing side; the edge on the leading side and the edge on the trailing side each include a chamfered portion shorter than a sipe length of the sipe; a non-chamfered region in which other chamfered portions are not present is provided at portions facing the chamfered portions of the sipe; a maximum depth of the chamfered portion is less than a maximum depth of the sipe; a sipe width of the sipe is constant in a range from an end portion located on an inner side in a tire radial direction of the chamfered portion to a groove bottom of the sipe; and a raised bottom portion is disposed in at least one section of the chamfered portion.
US11524523B2	Omni-wheel brake devices and methods for braking an omni-wheel An omni-wheel may include a shaft, a plurality of rollers, and a braking device. The plurality of rollers may be circumferentially arranged about the shaft and arranged radially outward from the shaft. The braking device may include an at least one flexible clutch member, an at least one brake pad, and an actuator. The at least one flexible clutch member may have an outer diameter arranged about the shaft. The at least one brake pad may be arranged on the outer diameter of the at least one flexible clutch member. The actuator may be arranged to axially displace the at least one flexible clutch member. The at least one flexible clutch member may expand radially outward when axially displaced by the actuator, which may displace the at least one brake pad arranged on the outer diameter of the at least one flexible clutch member radially outward to contact at least one of the plurality of rollers, preventing rotation of the roller.
US11524522B2	Wheel locking device A device for locking the wheel of a vehicle. The device comprises a main module adapted to be attached to the wheel and configured to cover nuts or bolts for attaching the wheel to the vehicle. The device further comprises an insert structure comprising a first part and a second part wherein the first part engages the second part and wherein the insert structure is transferable from a first position to a second position upon compression of a spring. Moreover, the insert structure in said second position is adapted for insertion in the wheel concentrically to the axis of rotation of the wheel and the insert structure in said first position is adapted for fixating the insert structure in said wheel upon transfer to the first position after insertion in the wheel. The device further comprises a center bolt adapted to be connected through the main module to the second part of the insert structure by means of a threading as well as a locking mechanism adapted to be arranged in a locking state in which the locking mechanism prevents the center bolt from rotating relative the main module, and in an open state in which the locking mechanism allows the center bolt to rotate relative the main module.
US11524519B2	Customizable therapy clip for a writing instrument A clip comprised of removably attached components. The clip may be attached to a writing instrument, such as a pencil, or stylus. The surface of the clip has male elements that allow the components to snap on to the clip so that the clip may be adorned. The components are secured to the clip so that they may rotate freely around the male element. The components may be comprised of decorative elements, such as jewels, initials, logos, or pictures. The components may be comprised of a utilitarian element, such as a lanyard, or a flashing light to indicate an incoming email. The components may have a tactile surface comprised of bumps, or waves. The components may comprise of movable elements such as a rolling ball, or star that spins. The tactile surface and moving elements of a component may aid in the treatment of anxiety and attention deficit disorders.
US11524516B2	Security ink system A security system, such as a banknote, comprises: i) a substrate, ii) a first ink, which is applied on at least a part of at least one surface of the substrate, wherein the first ink includes at least one IR luminescent dye and/or at least one IR luminescent pigment, and iii) a second non-luminescent ink, which is applied on at least a part of at least one surface of the substrate onto which the first ink is/are applied, wherein the second ink includes at least one non-luminescent IR absorbing pigment and/or a least one non-luminescent IR absorbing dye, wherein the first ink and the second ink at least partially overlap on the at least one surface of the substrate, wherein the second ink is applied in the overlapping area onto the first ink, and wherein the emission spectrum of the first ink and the absorption spectrum of the second ink at least partially overlap.
US11524513B2	Conveyance apparatus, image defect detection device, and image forming system A conveyance apparatus includes a plurality of conveyors and an image reader. The plurality of conveyors conveys a recording material. The image reader reads a pattern image on the recording material being conveyed. The conveyance apparatus further includes circuitry to control the image reader. The circuitry controls the image reader to read the pattern image on the recording material in a period including a timing at which a trailing edge of the recording material being conveyed by at least two of the plurality of conveyors exits an upstream conveyor among the at least two of the plurality of conveyors in a direction of conveyance of the recording material.
US11524507B1	Garment packaging for direct-to-garment personalization kiosk In some embodiments, a direct-to-garment personalization system for personalizing an article includes a direct-to-garment printer configured to print a graphic onto the article; a hanger for supporting the article; a storage area containing the article supported on the hanger; and a transfer system configured to remove the article from the hanger in the storage area and move the article to the direct-to-garment printer. The hanger includes a first arm coupled to a second arm, wherein the arms are collapsible to a smaller size in response to a pull force; and a hook coupled to at least one of the first and second arms.
US11524499B2	Substrate, liquid ejection head, and manufacturing method thereof A substrate includes a first substrate which has a first substrate through hole, and a second substrate which has a second substrate through hole and directly or indirectly overlaps the first substrate, the first substrate through hole and the second substrate through hole directly or indirectly communicate with each other to form a liquid supply path and a width D1 of an opening portion of the first substrate through hole on a surface of the first substrate closer to the second substrate, a width D2 of an opening portion of the second substrate through hole on a surface of the second substrate closer to the first substrate, a width D3 of an opening portion of the second substrate through hole on a surface of the second substrate farther from the first substrate have a relationship of D1
US11524496B2	Image recording apparatus, control method, and storage medium A determination is made on whether or not a recording medium is held in a state where calibration is executable, and the execution is pending in a case where the recording medium is not held. When the execution is pending, the determination is made again after a predetermined period elapses, and the calibration is executed in a case where the recording medium is held.
US11524495B2	Closed loop feedback press The pressing of an article is achieved with a closed-loop feedback press. The closed-loop feedback press is effective to measure an amount of pressure applied and adjust the pressure to achieve a prescribed amount of compression on the article. Further, the press may leverage a closed-loop feedback system to maintain a consistent temperature of one or more platens. The press is able to adjust a pressure applied one or more times during a pressing operation to accelerate a temperature change in the pressed article while reducing the pressure applied as the temperature approaches a target temperature to limit unintentional deformation and bleeding of the pressed material of the article.
US11524492B2	Polyamide resin composition and molded article comprising the same A polyamide resin composition and a molded article manufactured using the same. The polyamide resin composition includes: about 15 wt % to about 49 wt % of an aromatic polyamide resin including a repeat unit represented by Formula 1 and a repeat unit represented by Formula 2 as defined in the specification; about 1 wt % to about 30 wt % of a polyamide resin having a glass transition temperature of about 40° C. to about 120° C.; about 1 wt % to about 20 wt % of an olefin-based copolymer; and about 30 wt % to about 50 wt % of calcium carbonate. The polyamide resin composition and the molded article produced using the same can have good properties in terms of plating adhesion, impact resistance, thermal resistance, fluidity, and/or appearance, and the like.
US11524489B2	Film, roll and adhesive tape A film that is excellent in easy cuttability and linear cuttability and suppressed in breakability in processing, and a roll and a pressure-sensitive adhesive tape that includes the film. The film has the tensile strength in one direction is 1.1 to 2.5 kN/m and the tensile strength in a direction orthogonal to the one direction is 3.0 to 10 kN/m, or the tensile strain at tensile strength in one direction is 50 to 150% and the tensile strain at tensile strength in a direction orthogonal to the one direction is 8 to 20%.
US11524481B2	Low refractive index layer, laminated film, method for producing low refractive index layer, method for producing laminated film, optical element, and image display device The present invention aims to provide a low refractive index layer that can attain both a low refractive index and a high mechanical strength even when it has a large thickness. The low refractive index layer of the present invention is a low refractive index layer in the form of a void-containing layer, wherein hollow particles each having a void space inside are further contained in the void-containing layer, and the low refractive index layer has a refractive index of 1.25 or less.
US11524480B2	Adaptive microtexturing of a composite material An article including a composite including a subsurface structure and a second phase of material forming a coating on the subsurface structure. The coating includes a first region defining a first plurality of microtextures in an outer surface of the coating, where the first plurality of microtextures include an average bore width of less than about 250 micrometers (μm) and a first average bore depth, and a second region positioned adjacent to the first region wherein the coating defines a second plurality of microtextures on the outer surface of the coating, where the second plurality of microtextures include an average bore width of less than about 250 μm and a second average bore depth less than the first average bore depth.
US11524479B2	Natural nonwoven materials There is described a nonwoven material comprising a multilayered stack, the multilayered stack comprising discrete interconnected layers, each of the layers, which may be the same or different, comprising a composite fibre of from about 80 to 100% w/w leaf or stem fibre and from about 1 to 20% w/w of a polymer, wherein the polymer is fusible at a temperature of about 180° C. or less. There is also described a novel method of enzyme degumming leaf and/or stem fibres.
US11524475B2	Protective packaging longitudinal heat sealer A protective packaging formation device is provided herein. The device includes an inflation assembly having a fluid conduit that directs fluid between overlapping plies of a polymeric web. The device also includes a driving mechanism that drives the film in a downstream direction. The device also includes a sealing mechanism that includes a thin film heater that heats the plies to create a longitudinal seal that seals the plies of film together. The driving mechanism drives the web such that the web slides across the heating assembly in a downstream direction to trap fluid between the plies.
US11524473B1	Reinforced press base, piston cavity sleeve, and method of reinforcing a press base High pressure presses, components for high pressure presses and related methods are provided herein. In one embodiment of the invention, a press base may include a piston cavity formed in the press base and a piston cavity sleeve positioned in the piston cavity. The piston cavity sleeve may include a wall having an outer surface and an inner surface opposite the outer surface. The piston cavity sleeve may further include a floor having an upper surface and a lower surface opposite the upper surface. An outer radius may be formed at a juncture of the outer surface of the wall and lower surface of the floor and an inner radius may be formed at a juncture of the inner surface of the wall and upper surface of the floor. The inner radius may exhibit a radius of curvature that is greater than a radius of curvature of the outer radius.
US11524472B2	Method of manufacturing optical component having micro-structures A method of manufacturing an optical component having micro-structures is described. The method detects a crystallization temperature within a crystallization temperature interval for fully filling the molding material into a mold cavity to rapidly produce the optical element having a micro-structure with a large area.
US11524471B2	Method for fabricating thermoplastic composite parts A system and method for forming a composite part. The apparatus comprises a sleeve that molds a composite material. The sleeve has a first face and a second face. The second face has features to mold the composite material. The first face comprises a first inclined surface having an angle less than about 90 degrees and greater than about 0 degrees.
US11524468B2	Systems and methods for thermoplastic panel stretch/roll forming A thermoforming method includes forming a skin comprising a plurality of plies thermoplastic resin and fiber, securing an edge of the skin to a mandrel, heating, via a heating element, the skin to a forming temperature, moving a thermoforming apparatus with respect to the mandrel, rolling at least one roller of the thermoforming apparatus along the skin in a direction away from the clamped edge of the skin in response to the thermoforming apparatus moving with respect to the mandrel, and in response to the at least one roller of the thermoforming apparatus rolling along the skin, compressing the skin between the at least one roller and the mandrel, consolidating the plurality of plies of material, and bending the skin to conform to a shape of the mandrel. The consolidated and formed skin is then cooled and removed from the mandrel.
US11524461B2	Data units for additive manufacturing In an example, a data unit includes a mounting to removably mount the data unit on a receiving portion of an additive manufacturing build material container, a data source to provide data comprising a plurality of additive manufacturing parameters and a communications interface to communicate with a reader of an additive manufacturing build material processing apparatus. The communications interface is to transmit data from the data source to the additive manufacturing build material processing apparatus.
US11524458B2	Laser pulse shaping for additive manufacturing The present disclosure relates to an apparatus for additively manufacturing a product in a layer-by-layer sequence, wherein the product is formed using powder particles deposited on an interface layer of a substrate. A laser generates first and second beam components. The second beam component has a higher power level and a shorter duration than the first beam component. A mask creates a 2D optical pattern in which only select portions of the second beam components can irradiate the powder particles. The first beam component heats the powder particles close to a melting point, where the particles experience surface tension forces relative to the interface layer. While the particles are heated, the second beam component further heats the particles and also melts the interface layer before the surface tension forces can act on and distort the particles, enabling the particles and the interface layer are able to bond together.
US11524456B2	Method of fabricating shaped object and forming apparatus A method of fabricating a shaped object includes: preparing a formation sheet including a base and a thermally expansive layer stacked on a first main surface of the base, the thermally expansive layer including a binder and thermally expandable material; heating the base of the formation sheet to a temperature lower than an expansion initiation temperature at which the thermally expandable material starts to expand; and heating the thermally expansive layer of the formation sheet after heating of the base, to a temperature higher than or equal to the expansion initiation temperature at which the thermally expandable material starts to expand, thereby causing expansion of the thermally expansive layer.
US11524448B2	Compositions and methods for fused filament fabrication A composition for fused filament fabrication may include polylactic acid resin and talc. The composition may range from 50% by weight to 99% by weight polylactic acid resin, and from 7% by weight to 40% by weight talc. The composition may be configured as filaments or pellets adapted to be used in a fused filament fabrication process. A method for generating a resin-based structure may include providing a resin source that may include polylactic acid resin and talc. The resin source may include from 50% by weight to 99% by weight polylactic acid resin, and from 7% by weight to 40% by weight talc. The method may also include heating the resin source to a temperature greater than the melting temperature for semi-crystalline resins or significantly greater than glass transition temperature for amorphous resins, and depositing the heated resin source in a layered manner to form the resin-based structure.
US11524437B2	Mold structure Provided is an improved mold structure, including a first mold base, a second mold base and two controllers. The first mold base and the second mold base are operably aligned. When the first mold base and the second mold base are in an aligned state, a mold cavity is jointly framed. Two gas passages, a first mold core and a second mold core are provided. The first mold base is provided with a runner. Two ends thereof are respectively connected to a material tube and a mold cavity of a molding machine. The first and second mold cores are made of porous material. Vent pipelines thereof are connected to the respective gas passages. The two controllers are respectively connected to the gas passages, and control the gas in and out such that the pressure in different areas in the mold cavity reaches a predetermined value, thereby controlling the flow direction of the raw material in the mold cavity.
US11524433B2	Injection molding machine An injection molding machine includes: a plunger provided inside a barrel and capable of moving forward and backward in an axial direction thereof and rotating about an axis thereof; a feed hole for feeding a molding material in liquid form into a front of the plunger; a packing provided on a backward side of the feed hole to prevent the molding material fed through the feed hole from flowing backward along the plunger; and a controller for controlling a retracting movement of the plunger based on pressure of the molding material fed from the feed hole to thereby perform metering. In this configuration, at least part of the feed hole is covered by a side surface of the plunger at least from start to end of the retracting movement.
US11524431B2	Method of manufacturing sandwich panel The invention relates to a method of manufacturing a sandwich panel comprises the steps of: a) providing a plate-shaped assembly of a first cover part and a second cover part and between these cover parts a core part of a thermoplastic material containing a physical blowing agent, b) heating the assembly resulting from step a) under pressure between press tools in a press to a foaming temperature below the glass transition temperature of the thermoplastic material in the core part, thereby effecting adhesion of the foamed core part to the first and second cover parts c) foaming the thermoplastic material in the core part under pressure and at the foaming temperature wherein the spacing between the press tools is increased; d) a cooling step of cooling the foamed sandwich panel resulting from step c), while the sandwich panel is maintained under pressure between the press tools; e) removing the thus cooled sandwich panel from the press; and f) drying the sandwich panel thus obtained; wherein the cooling step d) comprises.a first substep d1) of cooling the foamed assembly from the foaming temperature to an intermediate temperature in the range of 70-100° C. at a first cooling rate and a second substep d2) of cooling the foamed assembly from the intermediate temperature to ambient temperature at a second cooling rate, the second cooling rate is less than the first cooling rate.
US11524430B2	Structure, and method for manufacturing same The present application provides a structure excellent in sound absorbing performance According to the present invention, provided is a structure comprising a foam molded body and a porous skin sheet, wherein the skin sheet is integrally molded with the foam molded body; the foam molded body and comprises a wide space therein; and Sw/Ft≥0.5, where Ft represents the thickness of the foam molded body at a position in which the thickness of the wide space is maximum, and Sw represents the width of the wide space.
US11524428B2	Cleaning agent for molding-machine cleaning and cleaning method The object of the present invention is to provide a cleaning agent that is superior in the initial cleaning effect and allows residues to be easily distributed evenly in the next fabricated molded article. The object is achieved by a cleaning agent used for a molding machine and including a thermoplastic resin and a glass wool.
US11524424B2	Production of oriented strand board A method of making a wood particle board containing sticking type resin coated wood particles wherein the top of a layup of the coated wood particles is smoothed to provide a smooth a top surface on the layup and a release agent is applied on the top surface and the so coated layup is consolidated into a board in a consolidating press under heat and pressure with the coated top surface in direct contact with a press platen.
US11524422B2	Method of operating a flat-bed die cutter In a method of operating a flat-bed die-cutter a printing substrate in the form of a web is fed to a die-cutting module of the flat-bed die-cutter, a web section is severed from the web and removed as waste. The web is guided through the die-cutting module and the web section is severed from the web in or downstream of the die-cutting module and removed as waste. Products are thus formed by die-cutting a web while reducing waste and periods of standstill.
US11524421B2	Folding knife A folding knife having an elongated handle defining a finger hole proximate one end of the handle and a blade having a cutting edge and pivotally connected to the handle and configured to move with respect to the handle between a retracted position and an extended position. The blade is configured such that a portion of the cutting edge extends into the finger hole upon the blade being in the retracted position. A blade cover is connected to the handle and is configured to move between an operable position and a withdrawn position. A spring is configured to contact and automatically move the blade cover from the operable position towards the withdrawn position, whereby, as the blade reaches the retracted position, the blade cover is automatically moved to the operable position and covers the portion of the cutting edge of the blade extending into the finger hole, and upon the blade moving towards the extended position, the spring automatically moves the blade cover from the operable position towards the withdrawn position.
US11524420B2	Razor A razor has a rigid metal body member with a thickness and a plurality of apertures therein. The rigid metal body member has a skin-engaging surface. Each aperture has a cutting blade adjacent the skin-engaging surface. The thickness of the rigid metal body member is from 2 mm to 10 mm.
US11524409B2	Method and device for efficiently ascertaining output signals of a machine learning system A method for efficiently ascertaining output signals of a sequence of output signals with the aid of a sequence of layers of a machine learning system, in particular a neural network, from a sequence of input signals. The neural network is supplied in succession with the input signals of the sequence of input signals in a sequence of discrete time increments. At the discrete time increments, signals present in the network are in each case further propagated through a layer of the sequence of layers.
US11524406B2	Calibration method and device for robotic arm system A calibration method for a robotic arm system is provided. The method includes: capturing an image of a calibration object fixed to a front end of the robotic arm by a visual device, wherein a pedestal of the robotic arm has a pedestal coordinate system, and the front end of the robotic arm has a first relative relationship with the pedestal, the front end of the robotic arm has a second relative relationship with the calibration object; receiving the image and obtaining three-dimensional feature data of the calibration object according to the image by a computing device; and computing a third relative relationship between the visual device and the pedestal according to the three-dimensional feature data, the first relative relationship, and the second relative relationship to calibrate a position error between a physical location of the calibration object and a predictive positioning-location generated by the visual device.
US11524405B2	Screwing device A screwing device including: a container for screws; a manipulator having an effector to pick up a screw; an isolating unit connected to the container to provide the screw from the container at an interface such that a head of the screw is accessible to the effector; and a control unit to control the manipulator in executing a control program to perform operations including: guiding the effector along a trajectory having an orientation to the screw head at the interface, wherein the orientation is defined for locations along the trajectory; and executing force-regulated, impedance-regulated, and/or admittance-regulated periodic and closed tilting movements of the effector in relation to its orientation until a condition for a torque, a force, or a time for carrying out the tilting movements is reached or exceeded, and/or a force/torque and/or a position/speed signature at the effector is reached or exceeded, indicating successful pick-up of the screw.
US11524404B2	Robot system and control method thereof A robot system can include a main body; a manipulator installed on the main body; a sensor configured to detect an object approaching a restricted region including the manipulator; a camera configured to monitor the restricted region and the object approaching the restricted region; a storage configured to store a material for an operation of the manipulator, the storage including an inlet for receiving the material; a remaining amount sensor configured to detect an amount of the material remaining in the storage; and a controller configured to change the restricted region based on at least one of a result of detection of the remaining amount sensor and image information of the camera, and in response to the sensor detecting that the object is within the restricted region, stop manipulation of the manipulator.
US11524403B2	Vacuum-based end effector for engaging parcels A vacuum-based end effector for engaging parcels includes a base plate, one or more vacuum cups of a first type, and one or more vacuum cups of a second type. Each vacuum cup of the vacuum-based end effector is configured to be placed in fluid communication with a vacuum source to provide the vacuum cup with a suction force which can be used to engage and grasp parcels. Each vacuum cup includes a bellows defining a pathway for a flow of air and a lip connected to the bellows. Each lip of the one or more vacuum cups of the first type comprises a foam lip, and each lip of the one or more vacuum cups of the second type comprises an elastomeric lip. The vacuum-based end effector can be combined with a robot to provide an improved system for engaging parcels.
US11524401B1	Learning skills from video demonstrations A method includes determining motion imitation information for causing a system to imitate a physical task using a first machine learning model that is trained using motion information that represents a performance of the physical task, determining a predicted correction based on the motion information and a current state from the system using a second machine learning model that is trained using the motion information, determining an action to be performed by the system based on the motion imitation information and the predicted correction; and controlling motion of the system in accordance with the action.
US11524395B2	Signal processing apparatus and electric tool A signal processing apparatus for an electric tool is provided for generating a motor control signal for controlling a motor by performing a smoothing process on a torque value signal from a torque sensor of an electric tool by using a filter. The signal processing apparatus includes a half width detector circuit that detects a half width of the torque value signal; and a calculator circuit that controls a cut-off frequency of the filter to change the cut-off frequency according to a number of hits of the electric tool, based on the detected half width of the torque value signal.
US11524392B2	Minimal contact gripping of thin optical devices Embodiments described herein provide for devices and methods for retaining optical devices. The devices and methods described herein provide for retention of the substrate without contacting sensitive portions of the substrate. The devices and methods utilize retention pads or vacuum pins to contact the exclusion zones i.e., inactive areas of the substrate to retain the substrate and prevent the substrate from moving laterally. Additionally, a holding force retains the substrate in the vertical direction, without contacting the substrate. The methods provide for adjusting the devices to account for multiple geometries of the substrate. The methods further provide for adjusting the devices, such as adjusting a gap between the optical device and a suction pad, to alter the holding force of the devices on the optical devices.
US11524388B2	Mirror finishing method and production method of mirror finishing tool A mirror finishing method for forming a mirror surface on a workpiece with a mirror finishing tool including a conically shaped cutting tool made of polycrystalline diamond or cubic boron nitride that is attached to a distal end of a shank, performs mirror polishing by abutting a conical surface of the cutting tool against a machined surface of the workpiece with the shank tilted with respect to the machined surface of the workpiece.
US11524387B2	Apparatus and method for peening of machine components A peening device for treating a component includes a shot media propulsion source configured to propel a quantity of shot media. The device also includes a plurality of treatment enclosures each selectively coupleable to the shot media propulsion source. Each of the treatment enclosures has a shape complementary to a corresponding one of a plurality of portions of the component, such that each treatment enclosure and the corresponding portion cooperate to enclose the shot media.
US11524382B2	Polishing apparatus using machine learning and compensation for pad thickness Data received from an in-situ monitoring system includes, for each scan of a sensor, a plurality of measured signal values for a plurality of different locations on a layer. A thickness of a polishing pad is determined based on the data from the in-situ monitoring system. For each scan, a portion of the measured signal values are adjusted based on the thickness of the polishing pad. For each scan of the plurality of scans and each location of the plurality of different locations, a value is generated representing a thickness of the layer at the location. This includes processing the adjusted signal values using one or more processors configured by machine learning. A polishing endpoint is detected or a polishing parameter is modified based on the values representing the thicknesses at the plurality of different locations.
US11524376B2	Tapered template guided system for a router Tapered, stepped, or non-tapered router guide templates, and optionally combined template holder system, each template comprising: a base portion, a top portion, at least one of an exterior surface interconnecting the base portion and the top portion along an outer periphery of the template and an interior surface interconnecting the base portion and the top portion along an inner periphery of the template, wherein optionally one of the exterior surface and the interior surface may be continuously tapered between the base portion and the top portion, or stepped, and wherein the base portion is adapted for removable and adjustable interconnection with the template holder system.
US11524361B2	Laser welding method A method for laser keyhole welding is disclosed to weld two pieces together made of a metal alloy. The method independently adjusts power in a focused center beam and power in a concentric focused annular beam. At the termination of a weld, the power of the annular beam is reduced, motion of the focused beams is stopped, the power of the center beam is increased, and the power of both beams is initially ramped down rapidly and then ramped down slowly. Increasing the power of the center beam equalizes the temperature of both pieces prior to solidification and cooling at the termination of the weld. An additional pulse of power may be applied to prevent the formation of defects or to erase any defects.
US11524359B2	Low temperature direct bonding of aluminum nitride to AlSiC substrates Disclosed herein are power electronic modules formed by directly bonding a heat sink to a dielectric substrate using transition liquid phase bonding.
US11524357B2	Modular welding system A welding system includes power conversion circuitry configured to convert input power to weld power and a first housing surface. The first housing surface includes a first mating geometry configured to mate with a first complementary geometry of a first modular surface of a first modular component of the welding system.
US11524352B2	Laminated molding and method of manufacturing laminated molding An additively manufactured object formed by depositing weld bead layers, each of the weld bead layers being obtained by melting and solidifying a filler metal made of a mild steel, the additively manufactured object includes a plurality of the weld bead layers having a ferrite phase with an average grain diameter of 11 μm or less in a part except for a surface oxide film.
US11524351B2	Multistage joining process with thermal sprayed layers Method for joining of at least two unweldable materials, non-weldable directly to each other with thermal joining processes in a lap joint configuration, where a two step sequence is used consisting of a first step to apply a thermomechanical or mechanical surface protection layer on the surface of an unweldable material and a second step, where a thermal joining process is used to joint the sprayed layer with an applied layer sheet.
US11524344B2	Rotationally asymmetric cutting insert having a single radially extending cutting-edge portion and rotary cutting tool A cutting insert rotatable about an axis, has opposing front and rear surfaces interconnected by an insert peripheral surface, the insert peripheral surface having first and second side surfaces spaced apart by first and second land surfaces. First and second land edges extend along the first and second land surfaces, respectively. A first front edge formed at the intersection of the front surface and the first side surface includes a cutting-edge portion, and a second front edge formed at the intersection of the front surface and the second side surface is devoid of a cutting-edge portion. A cutting profile formed by rotating the cutting-edge portion about the axis is located axially forward of the second front edge. The cutting insert is releasably secured to a tool shank, the cutting insert being located between two protuberances protruding from a forward end portion of the tool shank.
US11524343B2	Machining station A machining station especially arranged to carry out deep drill and milling operations is disclosed. The machining station now proposed presents a specific structural arrangement, enables the incorporation, contrary to already existing stations, of an axis dedicated to deep drilling, favoring the use of deep drill tools under ideal conditions, without size restriction. Accordingly, the station is comprised of an operating base, on which there lays an operating module and an arrangement module. This new arrangement for the machining station is therefore more versatile and adaptable to the specificities programmed for each part to be machined.
US11524340B2	Tool body including a damping apparatus and a machining tool having such a tool body A tool body includes a damping apparatus for damping vibrations in a machining tool having, besides the tool body, a member with at least one cutting edge to be secured to the tool body. The damping apparatus is arranged in an internal room of the tool body and includes a damper mass body with an axial bore and a central tube extending through the bore and which is rigidly secured to the damper mass body inside the through bore. A central tube is also at both ends thereof rigidly connected to a tool body fixed part and the central tube is made of a material with a spring property allowing the damper mass body to oscillate in the internal room perpendicularly to the longitudinal extension of the central tube.
US11524336B2	Sintered body manufacturing method A sintered body manufacturing apparatus includes a compacting apparatus configured to press a raw powder containing a metal powder into a green compact, a machining apparatus configured to perform a cutting operation on the green compact to produce an unsintered materials, and a green compact conveying path configured to connect the compacting apparatus in series to the machining apparatus to convey green compacts one by one from the compacting apparatus to the machining apparatus.
US11524334B1	Method and apparatus for avoiding erosion in a high pressure die casting shot sleeve for use with low iron aluminum silicon alloys Methods for replacing an impingement site of a shot sleeve with an erosion resistant material, for manufacturing a shot sleeve for high pressure die casting of Aluminum Silicon alloys having an erosion resistant material at an impingement site, and for manufacturing a shot sleeve for high pressure die casting of aluminum silicon alloys containing 0.40% max Fe, having an erosion resistant material at an impingement site are disclosed. The shot sleeve assembly includes a shot sleeve including a pouring hole and a, impingement site. In certain embodiments a bushing assembly is implemented. The impingement site or bushing assembly includes a refractory metal tube constructed of erosion resistant material.
US11524326B2	Method for operating a forming press A method for operating a forming press which includes a plurality of press components and a plurality of tool components. The forming press has at least one force sensor and at least one force actuator, each arranged in a press and/or tool component. A forming simulation is carried out, which takes into consideration an elastic behavior of the press and/or tool components. Target values of forces acting on at least one press and/or tool component are determined by the forming simulation. A forming process is carried out by the forming press. During the forming process, actual values of forces acting on the press and/or tool components are measured by the force sensor and the force actuator is actuated via a control loop such that the actual values correspond to the target values from the forming simulation.
US11524317B2	Process for electron beam curable inkjet formulations The present invention provides a method for printing energy-curable ink and coating compositions that have good adhesion to substrates, good print quality, solvent and scratch resistance, and low potential for migration of uncured monomers. The method comprises the steps of printing the ink or coating onto a substrate; partially curing the printed ink or coating by irradiating with UV energy; optionally printing and partially UV curing additional ink layers printed on the first layer; and completing curing via exposure to electron beam radiation, wherein the EB cure dose is greater than or equal to 20 kGy, and the accelerating voltage is greater than or equal to 70 keV.
US11524316B2	Two-dimensional coordination polymers Forming a two-dimensional polymeric sheet includes translating a portion of a flexible substrate through a first liquid precursor to coat the portion of the flexible substrate with the first liquid precursor, thereby yielding a precursor-coated portion of the flexible substrate. The precursor-coated portion of the flexible substrate is translated through an interface between the first liquid precursor and a second liquid precursor, thereby reacting the first liquid precursor on the precursor-coated portion of the flexible substrate with the second liquid precursor to yield a polymer-coated portion of the flexible substrate.
US11524315B2	Support unit, substrate treating apparatus including the same, and substrate treating method using the substrate treating apparatus An apparatus for treating a substrate includes a housing having a treatment space inside, a gas supply unit that supplies a hydrophobic gas into the treatment space to hydrophobicize the substrate, and a support unit that supports the substrate in the treatment space. The support unit includes a support plate, a heating member that heats the substrate placed on the support plate, and a height adjustment member that changes a position of the substrate between a first position spaced apart upward from an upper surface of the support plate by a first distance and a second position spaced apart upward from the upper surface of the support plate by a second distance, and the second position is a higher position than the first position.
US11524314B2	Substrate processing method and substrate processing device In a second liquid supply step, a second liquid film and a first liquid film surrounding a side of the second liquid film are formed on an upper surface of a substrate. Then, in a vapor layer formation step, by heating the substrate, a second vapor layer is formed by evaporating the second liquid contacting the upper surface of the substrate, and the second liquid film is held on the second vapor layer. Since the second liquid included in the second liquid film has a high vapor pressure, a height position of a lower surface of the floating second liquid film may be kept high. By blowing a gas to the floating second liquid film, a hole is formed in the second liquid film, and by expanding the hole toward an outer periphery of the substrate, the first liquid and the second liquid are removed outside the substrate.
US11524311B2	Spray dispenser The invention relates to a dispenser 20 for the spray delivery of a preparation 18. The dispenser comprises: a reservoir 22 suitable for containing the preparation 18, a mechanical pump 24, a load chamber 26, a nozzle 28 having a delivery axis, and a delivery cone 30 having an axis. The mechanical pump is able, whenever operated: to take a predetermined amount of preparation from the reservoir, to supply said amount of preparation to the load chamber upstream of the nozzle, and to create a delivery pressure in the load chamber. The nozzle is able to deliver said amount of preparation in the form of an aerosol spray 180. The dispenser according to the invention is characterized in that the delivery cone comprises, in the proximity of the nozzle, at least one through-hole 320 suitable for putting the inside of the delivery cone into communication with the surrounding environment.
US11524310B2	Device and method for measuring a varnish jet for varnishing circuit boards The present invention relates to devices and methods for measuring a varnish jet for a varnishing process for electronic subassemblies. Said devices and methods allow the width and symmetry of the varnish jet to be determined without performing any relative movement between the varnish jet and the sensor.
US11524308B2	Handheld spray device A handheld spray device has a flexible bellow coupled to a base to thereby retain liquid therein. The bellow has a bulbous section adjacent the base, narrows away from the base to terminal section opposite the base and has a side notch formed at one side of the bellow between the bulbous section and the terminal section. The base also has a nozzle therethrough such that when the bellow is squeezed in use, the liquid is forced via the nozzle.
US11524307B2	Spraying device and method for adjusting the spraying device A spraying device includes a spray head, which is connected to a supply line, via which a pressurized fluid can be conveyed. The spraying device includes a metering screw for influencing the fluid jet passing out of the spray head. The spraying device is designed such that a pointer element having at least one marking is connected to the metering screw in a rotationally fixed, yet detachable manner.
US11524306B2	Surface cleaning apparatus, cyclonic air treatment member and surface cleaning apparatus including the same A surface cleaning apparatus comprises an air treatment chamber with a moveable member positioned therein. An end wall of the air treatment chamber is openable in response to a moveable member being longitudinally translated through at least the portion of the air treatment chamber. The driving assembly includes a handle and a drive rod that is rotatably mounted about a longitudinally extending axis of the drive rod between a stored position in which the moveable member is in a stored position and an operable position in which the moveable member is translatable through at least a portion of the chamber. In the stored position, the handle is longitudinally spaced from the first and second ends of the air treatment chamber and, when the driving assembly is in the operable position, the driving assembly is operable to longitudinally translate the moveable member through at least a portion of the chamber.
US11524305B2	Electrostatic precipitator apparatus Disclosed herein is an electrostatic precipitator apparatus that includes a housing having an inlet, into which gas is introduced, and an outlet from which the gas is discharged, and a collection module installed in the housing. The collection module includes a plurality of discharge electrodes, to which a voltage is applied, and a plurality of collection electrodes grounded and disposed between the discharge electrodes. The apparatus further comprises a washing water feeder to spray washing water to the collection module, and a washing water treatment device disposed beneath the collection module to accommodate the washing water dropped from the collection module.
US11524304B2	Electrostatic charging air cleaning device and collection electrode A method of forming a collection electrode for an electrostatic charging air cleaning device. The method includes forming a slurry including a carbon black powder material, a polymeric binder material and a liquid solvent material. The method further includes applying the slurry to a substrate material. The method also includes curing the slurry to obtain a coating layer on the substrate material to form the collection electrode.
US11524303B2	Tool system The invention relates to a tool for securing on a tool holder of a machine tool for machining vegetable and/or mineral materials, comprising a tool body which is equipped with a machining attachment that points in a tool feeding direction and comprises a cutting region, in particular a cutting element, and on which a fitting element for meshing with a mating element provided on the tool holder is formed on a support surface facing the tool holder. The dependability and operational reliability when using a machine tool can be ensured if the fitting element has at least two molded regions with different contour regions over the vertical course of the fitting element with respect to the support surface.
US11524302B2	System with securing frame A system includes a platform having an upper surface and defining a recess having a floor, the recess configured to seat a dish, and a movable securing frame that is movably connected with the platform, the frame including a lift support having an upper surface that is movable along a path from a first location that is beneath the floor of the recess, through the recess, to a second location that is coplanar with the upper surface of the platform. A motor configured to cause oscillation of the platform and the movable securing frame can be used. A method of using the system can include placing a dish above a recess defined by an upper surface of a platform, and lowering the frame with respect to the platform, thereby seating the dish within the recess.
US11524301B2	Molecular diagnostic assay system Improved sub-assemblies and methods of control for use in a diagnostic assay system adapted to receive an assay cartridge are provided herein. Such sub-assemblies include: a brushless DC motor, a door opening/closing mechanism and cartridge loading mechanism, a syringe and valve drive mechanism assembly, a sonication horn, a thermal control device and optical detection/excitation device. Such systems can further include a communications unit configured to wirelessly communicate with a mobile device of a user so as to receive a user input relating to functionality of the system with respect to an assay cartridge received therein and relaying a diagnostic result relating to the assay cartridge to the mobile device.
US11524294B2	Microfluidic sorting devices and methods The present invention relates to the field of microfluidics and in particular to devices and methods for sorting objects in microfluidic channels. These devices and methods allow for fast and robust sorting in two-way and multi-way setups. They also enable sorting over extended periods of time.
US11524293B2	Cell separation device, method and system Cell separation systems, and methods for separating cells from microcarriers, and harvesting the separated cells, are provided, wherein the system comprises a cell separation device, a cell settling device, and a cell screening device.
US11524291B2	Fluidic device A fluidic device (10) is described. The fluidic device (10) comprises the first part (110) and the second part (120). The first part (110) comprises a first inlet (111) and a first outlet (112), mutually spaced apart. The second part (120) comprises a first chamber (121) arranged to contain a predetermined first amount A1 of a first fluid F1 therein and a first wall portion (122) arranged to contain, at least in part, the first fluid F1 in the first chamber (121). The fluidic device (10) is arrangeable in a first configuration, wherein the first part (110) is fluidically isolated from the first chamber (121). The fluidic device (10) is arrangeable in a second configuration, wherein the first inlet (111) and the first outlet (112) are fluidically coupled via the first chamber (121), whereby increasing a first pressure P1 in the first chamber (121) via the first inlet (111) urges at least a part of the predetermined first amount A1 of the first fluid F1 through the first outlet (112).
US11524289B2	Nanosplash: a saliva-based diagnostic for viral infection suitable for home use Provided herein are compositions and devices for diagnosing and treating a viral infection in a subject and/or detecting a viral nucleic acid in a sample. In one example, a sample is treated in a first chamber and the sample is flowed into a second chamber, where any pathogenic nucleic acid is detected by oligonucleotides that are specific to the pathogen under test. Further, the oligonucleotides comprise a cleavage site for a restriction enzyme in the second chamber, which cleaves oligonucleotide-pathogenic nucleic acid hybrid resulting in the exposure of an enzyme that was being held by the oligonucleotide to its substrate, which generates a colorimetric and/or another visual readout.
US11524288B2	Device for sample analysis A device for analysing a sample comprising a nucleic acid to be captured and detected using a test strip are described. The device comprises a resilient biasing member disposed in an analysis chamber containing the test strip. The resilient biasing member exerts a force against the test strip sufficient to urge it into the sample chamber when it is in communication with the analysis chamber. This ensures that the test strip is reliably introduced into the sample chamber when it is in communication with the analysis chamber. In one embodiment, the sample chamber comprises guide members for guiding the test strip into the sample chamber. A free end of each guide member is shaped to prevent significant rotation of the test strip, so that the test strip is in correct alignment in the sample chamber for automatic reading of the test result, for example by a camera or optical reader.
US11524287B2	Automatic pipetting device for transferring samples and/or reagents and method for transferring liquid samples and/or reagents Aspects of the present disclosure relate to methods and devices for automatically transferring samples and/or reagents from sample vessels and/or reagent vessels into at least one receiving vessel In one example embodiment, a pipetting device is disclosed including a pipettor that is movable along a first direction and has at least one first pipetting needle that is movable along an arm of the pipettor along a second direction, substantially normal to the first direction. The pipetting needle is lowerable along a third direction into the individual vessels. In some specific embodiments, the arm of the movable pipettor has at least one second pipetting needle which, regardless of the current position of the first pipetting needle, is movable past the first pipetting needle and is lowerable into the individual vessels.
US11524281B2	Phosphorus-containing molecular sieve, its preparation and application thereof A phosphorus-containing molecular sieve has a phosphorus content of about 0.3-5 wt %, a pore volume of about 0.2-0.95 ml/g, and a ratio of B acid content to L acid content of about 2-10. The molecular sieve has a specific combination of characteristics, including a high ratio of B acid content to L acid content, thereby exhibiting higher hydrocracking activity and ring-opening selectivity when used in the preparation of a hydrocracking catalyst.
US11524280B2	Low-platinum catalyst based on nitride nanoparticles and preparation method thereof The present invention discloses a low-platinum catalyst based on nitride nanoparticles and a preparation method thereof. A component of an active metal of the catalyst directly clades on a surface of nitride particles or a surface of nitride particles loaded on a carbon support in an ultrathin atomic layer form. Preparation steps including: preparing a transition-metal ammonia complex first, nitriding the obtained ammonia complex solid under an atmosphere of ammonia gas to obtain nitride nanoparticles; loading the nitride nanoparticles on a surface of a working electrode, depositing an active component on a surface of the nitride nanoparticles by pulsed deposition, to obtain the low platinum loading catalyst using a nitride as a substrate. The catalyst may be used as an anode or a cathode catalyst of a low temperature fuel cell, has very high catalytic activity and stability, can greatly reduce a usage amount of a precious metal in the fuel cell, and greatly reduces a cost of the fuel cell. The present invention has important characteristics of being controllable in deposition amount, simple and convenient to operate, free of protection of inert atmosphere, and etc., and is suitable for large-scale industrial production.
US11524278B2	Hydrotreating catalyst with a titanium containing carrier and sulfur containing organic additive Generally, it is disclosed a catalyst for use in a hydrotreating hydrocarbon feedstocks and the method of making such catalyst. It is generically provided that the catalyst comprises at least one Group VIB metal component, at least one Group VIII metal component, about (1) to (about (30) wt % C, and preferably about (1) to about (20) wt % C, and more preferably about (5) to about 15 wt % C of one or more sulfur containing organic additive and a titanium-containing carrier component, wherein the amount of the titanium component is in the range of about (3) to (about (60) wt %, expressed as an oxide (Ti02) and based on the total weight of the catalyst. The titanium-containing carrier is formed by co-extruding or precipitating a titanium source with a Al203 precursor to form a porous support material comprising Al203 or by impregnating a titanium source onto a porous support material comprising Al203.
US11524277B2	Catalyst for mass production of multi-wall carbon nanotubes Provided is a catalyst for manufacturing multi-wall carbon nanotubes, the catalyst including metal components according to Ma:Mb=x:y, and having a hollow structure with a thickness of 0.5-10 μm. In the above equation, Ma represents at least two metals selected from Fe, Ni, Co, Mn, Cr, Mo, V, W, Sn, and Cu; Mb represents at least one metal selected from Mg, Al, Si, and Zr; x and y each represent the molar ratio of Ma and Mb; and x+y=10, 2.0≤x≤7.5, and 2.5≤y≤8.0.
US11524276B2	P-type TiO2/n-type WO3 heterojunction catalyst, its preparation and use in photochemical synthesis of fuels Provided is a p-type TiO2/n-type WO3 heterojunction catalyst and a preparation method and use thereof. The catalyst comprises p-type TiO2 and n-type WO3 supported on a surface of the p-type TiO2.
US11524273B1	Natural zeolite block for improving water quality and method for manufacturing same A natural zeolite block for improving water quality that is capable of being built in rivers, streams, and reservoirs having point and non-point pollutant sources to purify the water polluted by pollutants, to remove the eutrophication in the water to prevent the occurrence of green and red tides, and to consistently purify heavy metals and all kinds of harmful substances flowing into the water and to a method for manufacturing the same.
US11524271B2	Thin film getter and manufacturing method therefor A thin film getter is provided. The thin film getter comprises a substrate and an absorption layer on the substrate, wherein the absorption layer comprises a getter material for absorbing target gas and an auxiliary material for providing a moving path of the target gas, and the getter material can be divided into a plurality of getter regions by the auxiliary material.
US11524267B2	Resistivity value regulating device and resistivity value regulating method A resistivity regulating apparatus includes: a gas dissolving device that causes a regulating gas to dissolve in a liquid targeted for resistivity regulation to generate a treated liquid in which the regulating gas is dissolved in the liquid, the regulating gas being used to regulate a resistivity of the liquid; and a buffer tank to which the treated liquid discharged from the gas dissolving device is fed.
US11524266B1	Metal-organic framework/polymer foam composite materials and their uses in decontamination and/or ballistic protection A composite material is provided comprising a porous polymeric matrix having metal-organic framework (MOF) domains dispersed within the porous polymeric matrix, each of said MOF domains in fluid communication with the external environment through the pores in the porous polymeric matrix. A process of using the composite material to chemically modify or detoxify a chemical warfare agent or a toxic industrial chemical is also provided. The chemical warfare agent or the toxic industrial chemical is brought into contact with a MOF domain within the porous polymeric matrix so that the MOFs adsorb and chemically modify the chemical warfare agent or the toxic industrial chemical. A process for producing such a composite material is also disclosed.
US11524263B1	Filtration processes and systems Water or wastewater filtration processes and systems have a plurality of membrane modules, each having filter media therein, the plurality of membrane modules arranged in parallel fluid flow, a main bottom feed conduit, a main top feed conduit, and separate feed conduits fluidly connecting the main bottom feed conduits and the main top feed conduits to respective membrane modules. A main filtrate conduit, and separate filtrate conduits fluidly connect respective membrane modules to the main filtrate conduit. A backwash conduit fluidly connects the main filtrate conduit to respective membrane modules through the main top and bottom feed conduits. A pump having a pump feed conduit and a pump discharge conduit, the pump discharge conduit fluidly connected to the main top and bottom feed conduits, and a plurality of automatically controllable valves positioned in the main top and bottom feed conduits, the main filtrate conduit, the pump discharge conduit, and the backwash conduit, with a controller configured to actuate the plurality of automatically controllable valves to control feed and backwash flows through the membrane modules using pressure developed only by the pump. The pump is preferably operated by a variable-speed prime mover.
US11524262B2	Devices, systems, and methods for continuous processing with alternating tangential flow The present disclosure relates to tangential flow filters, membranes, and ultrafiltration membranes, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same. In an aspect, an alternating tangential flow system for continuous processing may include a feed line containing a fluid. A retentate line may be in fluid communication with the feed line. A first diaphragm may be at an inlet of the retentate line configured to pump fluid toward an outlet of the retentate line. A second diaphragm may be at the outlet of the retentate line configured to pump fluid toward the inlet of the retentate line. A membrane may be in fluid communication with the retentate line between the first diaphragm and the second diaphragm. A retentate pump may be at the retentate outlet configured to pump the fluid out of the retentate line.
US11524258B2	Adsorbent material module, adsorbent material structure and gas filtration mask An adsorbent material module includes a plurality of tubular adsorbent materials and a plurality of medium materials. Each of the tubular adsorbent materials includes at least one channel and at least one adsorbent layer. The adsorbent layer surrounds the at least one channel. The medium materials are coated on two ends of each of the tubular adsorbent materials, respectively, and the medium materials have a thermal conductivity function or an electrical conductivity function.
US11524255B2	Filter element center tube cage with poke yoke feature Various example embodiments relate to a filtration system. The filtration system includes a filter housing having a first housing end and a second housing end. The filter housing includes a housing cover defining an outlet. The housing cover includes a first guidance element extending from an internal portion of the housing cover axially away from the outlet. A second guidance element extends from the internal portion of the housing cover axially away from the outlet. A filter element has a first filter end and a second filter end. The filter element includes an end cap adjacent the first filter end and defining an end cap opening therethrough. The end cap includes a channel around the end cap opening. Filter media has a first media end and a second media end. The filter media extends axially from the first media end toward the second media end.
US11524254B2	Air filtering system An air filtering system includes a main system and a filtering module. The main system includes a main body having an air inlet, an air flow cover having an air outlet, and a primary filtering core replaceably disposed in the main body, wherein the air flow cover is detachably coupled at the main body to form a basic air filtering mode for filtering air from the air inlet to the air outlet through the primary filtering core. The filtering module is detachably coupled between the main body and the air flow cover to form an advanced air filtering mode, wherein the filtering module includes a secondary filtering core arranged for filtering the air after passing through the primary filtering core and before existing the air outlet.
US11524253B2	Wash press having improved rotor structure and housing for removing the same Provided is a wash press that separates liquids and solids from a waste stream. The wash press includes a tank having a semi-cylindrical shape. The tank has an inlet at a top of the tank for receiving a waste stream, a screen disposed in a portion of a bottom of the tank to permit liquid to pass therethrough, and an outlet for permitting solid materials separated from the liquid to pass therethrough. A rotor extends through the tank for transporting and dewatering the waste material entering the tank. The rotor includes a plurality of helical flights interconnected by paddle members to permit agitating the waste material. The wash press also includes a removable cover that enables the rotor to be lifted vertically, and a removably attached screen to facilitate replacement/repair of the same.
US11524244B1	Systems and methods for interactive physical environments An interactive physical environment providing entertainment to a patron includes a room formed by modular walls coupled to one another, a radio frequency identification (RFID) tag associated with the patron, and a control system. The room presents a game to a patron. The game includes a plurality of game components positionable in a first game configuration and a second game configuration. The first game configuration presenting a first challenge and the second game configuration presenting a second challenge. The second game configuration representing a solution to the first challenge. The control system receives patron identification information from the RFID tag associated with the patron. The control system selectively modifying the game presented by the room responsive to the received patron identification information.
US11524239B2	Gameplay system with play augmented by merchandise A gameplay system for providing interactivity based on a piece of merchandise or other object held or worn by a player. The system includes an object identification assembly, which may be a modified computer vision system, that operates to sense, for a gameplay participant, the presence and identity of a particular augmenting object such as themed merchandise worn or held by a rider of a theme park ride. The sensing may be performed by detecting an on-and-off pattern of light emitted from the object. In response, the gameplay system selects or modifies the interactive features of gameplay associated with the participant based on the identified augmenting object. For example, the interactive features are selected from memory by the gameplay system controller to match a character associated with the augmenting object during any interactive gameplay. This allows the gameplay participant to choose their abilities or powers for gameplay.
US11524234B2	Multiplayer video games with virtual characters having dynamically modified fields of view A multiplayer game implementing a method for generating a plurality of training virtual areas; generating at least one GUI to display a list of the plurality of training virtual areas; using the at least one GUI, enabling a player to choose one of the plurality of training virtual areas, wherein said one of the plurality of training virtual areas is associated with at least one attribute; allowing the player to navigate a virtual character to said one of the plurality of training virtual areas; monitoring an activity of the virtual character in said one of the plurality of training virtual areas; determining a value of the at least one attribute based on the monitored activity; and updating a first attributes profile of the virtual character to a second attributes profile based on the determined value of the at least one attribute.
US11524229B2	Methods, systems, and media for enhancing multiplayer game sessions with asymmetric information Mechanisms for enhancing multiplayer games are provided. In some implementations, the method comprises: detecting presence of a display device on a communications network; causing joining instructions to connect to a multiplayer game session to be displayed on the display device, wherein the joining instructions include server information for handling communications relating to the multiplayer game session over the communications network; receiving, from user devices over other communications networks, a request to join the multiplayer game session in response to displaying the joining instructions on the display device, wherein each of the user devices has a user display device; connecting each of the user devices over one of the other communications network to the display device presenting the multiplayer game session; initiating the multiplayer game session; determining, for the multiplayer game session, a first portion of game information to be presented on the display device and a second portion of game information to be presented on the user display device; and causing the first portion of game information to be displayed on the display device and the second portion of game information to be displayed on the user displayed device based on the determination.
US11524228B2	Sorting computer applications or computer files and indicating a sort attribute in a user interface Techniques are described for an intuitive and efficient GUI. In an example, a UI elements are presented on a GUI. Each one of the UI elements can corresponds to a set of computer applications or a set of computer files having attributes and each one of the UI elements can be selected to launch, as applicable, a computer application, a computer file, or a page about the computer application or computer file. A request to sort the UI elements can be received and can indicate at least one of the attributes as a sort factor. The UI elements are sorted accordingly and presented in an updated arrangement on the GUI. An attribute used in the sorting is presented within or in proximity to the UI elements, whereas another attribute not used in the sorting is not presented in the updated arrangement.
US11524224B2	Operating device Disclosed herein is an operating device connected to an information processing device, the operating device including an information transmitting section configured to receive an operation of a user and transmit operation information indicating content of the operation to the information processing device and a control processing section configured to perform control processing determined in advance according to the operation of the user, the information transmitting section transmitting state information indicating an execution state of the control processing to the information processing device.
US11524220B2	Ski binding A front ski binding assembly for a ski board, including a front boot-retaining mechanism retaining a boot in a slope ascending or descending utilisation, two first articulated arms pivotably mounted on a platform, a lateral security release device arranged in cooperation with first ends of first articulated arms to apply thereon a biasing force urging second ends of first articulated arms towards the longitudinal axis of the platform and allow each first articulated arms to rotate away from the longitudinal axis upon application by a boot of force higher than the biasing force on an interior surface of a first articulated arm, and two second articulated arms pivotably mounted about a second arbor and bearing at an end touring pins to engage corresponding mating members on front end sides of a boot in slope ascending utilisation, the second articulated arms being movable between an active and inactive position.
US11524217B2	Three-dimensional throwing game target apparatus A three-dimensional throwing game target apparatus includes platforms, bridge members, connectors and stanchions. The platforms include an outer wall and a platform receptacle ring that is adapted to receive a cup. Each of the bridge members include at least one bridge receptacle ring and a plurality of elongated girders extending outwardly from the bridge receptacle ring. The bridge members and the platforms may be detachably connected to one another in a horizontal plane. The stanchions are assembled to the platforms to support the receptacle rings at a plurality of different heights. The platforms, bridge members, connectors and stanchions may be assembled together to support the platform receptacle rings at selected vertically and horizontally spaced locations.
US11524215B2	Bat system with performance limiting structure and methods of making same A bat, which has a hollow barrel and an internal assembly configured to resist deformation of the hollow barrel, is disclosed. The internal assembly includes multiple rods disposed longitudinally within the hollow barrel. The internal assembly can include a deformable ring having a substantially circular outer wall having a diameter less than an inner diameter of the hollow barrel and multiple holes, with each hole configured to at least partially receive a rod of the multiple rods. The bat can have an end cap including end cap holes extending partially through the end cap, with each end cap hole configured to at least partially receive a rod.
US11524213B1	Systems and methods for additive manufacturing of a golf club having an insert structure A golf club head includes a body and an insert. The body defines a top side, a toe side, and a heel side, and includes a sole extending between the toe side and the heel side at a location on the body opposite to the top side. The body defines an internal volume defined between a ball-striking face and an internal wall. The insert is arranged within the internal volume and is formed layer by layer via an additive manufacturing process. The insert includes a lattice structure arranged between a rear surface of the ball-striking face and the internal wall. The lattice structure is in engagement with the rear surface and formed integrally with the ball-striking face and the internal wall.
US11524212B2	Golf club head customization A method of customizing a golf club, wherein the method includes generating operating data representative of a user operating a mechanical device. The operating data is generated by a first sensor sized and configured to be removably positioned in a mounting port formed on the mechanical device during operation of the mechanical device. The sensor is interchangeably positionable in the mounting port with at least one mass insert, the at least one mass insert being adapted to be interchangeably positioned in the mounting to provide at least two different mass configurations. The method further includes determining a recommended configuration of the at least one mass insert specific to the user based on the operating data generated by the sensor, and transmitting information representative of the recommended mass insert.
US11524211B2	Express sling for the sport of climbing with a lift system and visual display for the use frequency A quickdraw for sport climbing includes two carabiners held together by a connecting element having a central region which ends in a loop for the carabiners at each of the two end regions. This connecting element is provided with at least one sensor in the central region between the loops or near to one of the loops. As a result of a minimal movement or touch of the quickdraw, the at least one sensor, triggered by use of the quickdraw, emits an electronic signal which is received by a base station communicating with a smartphone and/or a computer so that the signal can be processed, stored and compared with previously stored signals in order to show or graphically represent the corresponding values resulting therefrom on the display.
US11524210B2	Method and program for providing remote rehabilitation training A method for providing remote rehabilitation training is provided. The method includes receiving, by a server, a connection request from a user terminal and a therapist terminal, receiving, by the server, first image data, about an appearance where a user performs rehabilitation training using a rehabilitation training device, in real time from the user terminal, receiving, by the server, second image data, provided to the user who is performing the rehabilitation training, in real time from a rehabilitation training display device, and transmitting, by the server, the received first image data and the received second image data to the therapist terminal in real time.
US11524209B1	Brainwave entrainment using virtual objects and gamification A system and method for brainwave entrainment using virtual objects and gamification, in which brainwave entrainment is applied using some combination of gaming elements, and brainwave activity is enhanced by virtue of the user's active participation. Long-term use is encouraged by virtue of the entertaining nature of the gamification. Depending on configuration, the system and method may comprise a display comprising virtual objects, a light-producing device (other than the display), an audio-producing device such as speakers or headphones, a haptic feedback device such as a vibratory motor, and various devices for monitoring the user's attention. A software application induces brainwave entrainment via one or more of the devices of the system.
US11524208B2	Indoor cycle machine providing user with virtual experience and exercise without straining knee Disclosed is an indoor cycle machine providing a user with virtual experience and exercise without straining knees, the indoor cycle machine comprising: a main body rotatably coupled onto a floor portion; a vertical support having one end coupled to the floor portion and an opposite end formed with a vertical through-hole; and a saddle support having one end coupled to an upper end of the main body and an opposite end formed with a saddle, in which the saddle support passes through the vertical through-hole such that the saddle support is rotatable inside the vertical through-hole, wherein the main body is rotated on the floor portion whenever the user steps on a pedal formed on the main body.
US11524207B2	Electric treadmill An electric treadmill includes a motor and a motor driving circuit. The motor driving circuit is operable to control electric current flow from a positive electrode through the motor to a negative electrode to drive the motor. The motor driving circuit has a switch path connected between the positive electrode and the negative electrode. The switch path has a resistance element and a switch element connected in series. When the motor driving circuit receives power, the switch element will be switched to a disconnected state, so that the resistance element is inactive. When the motor driving circuit does not receive power, the switch element will be switched to a connected state, so that the resistance element becomes a load between the positive electrode and the negative electrode for consuming power generated by the motor when the endless belt is driven to rotate by an external force.
US11524205B2	Exercise apparatus A piece of exercise equipment particularly for improved strength training exercises. More particularly, the invention relates to equipment that allows the user to vary tension when performing different exercises. The present invention is specifically designed for improved exercise through the variability of a tension component for use in such exercises as the plank exercise, sit-ups, push-ups and supine pull-ups that includes a core support, a guide arm, a head support, and a foot support that work in conjunction to most optimally support the user. The core support, the head support and the foot support are all connected, supported, and elevated from the floor by a central support system.
US11524199B2	Resistance training equipment A hex flex apparatus for improving resistance training is presented. The hex flex apparatus is useful for providing more than the standard two-dimension experience, in that a standard apparatus requires large jumps in band size and resistance to move up to the next level. The hex flex apparatus further adds a third dimension by allowing for smaller, more gradual increments to resistance, which leads to more and steadier strength progress before reaching a plateau or sticking point. A platform with two handles is described as is the band which is used to provide tension for resistance training. Further adjustable rods are shown which can be placed into various holes to control the tension and the rods have a ring magnet which provides for the rods being secured in the holes. The bands are further around the rods to access the value of the rods.
US11524193B2	Fire apparatus piercing tip ranging and alignment system A fire-fighting vehicle includes a boom assembly movably coupled to a chassis, a penetrating nozzle coupled to the boom assembly, an actuator that moves the penetrating nozzle relative to the chassis, and a controller operatively coupled to a sensor. The penetrating nozzle includes a piercing tip and an outlet configured to be selectively fluidly coupled to a supply of fire suppressant. The piercing tip is repositionable relative to a surface of an object having an interior cavity. The outlet supplies fire suppressant into the interior cavity when the piercing tip is within the interior cavity. The sensor provides data relating to at least one of a position and an orientation of the piercing tip relative to the surface. The controller determines an angular orientation of the piercing tip relative to the surface based on the data.
US11524190B1	Smoke baffle assembly and method of installation Technologies are described for a smoke baffle assembly and method of installation. The smoke baffle has a longitudinally extending base with an upper leg, a first leg, and a second leg. A first flange extends inward form the first leg and a second flange extends inward from the second leg. A smoke baffle holder holds an upper portion of a smoke baffle and has a first and second outward extending flange. Each of the outward extending flanges and inward extending flanges is configured and disposed for moving the outward extending flanges into the base and above the inward extending flanges and holding the smoke baffle in the base.
US11524187B1	Biometric and environmental monitoring and control system A wearable device for comprehensive bio-monitoring of physiologic metrics to determine metabolic, pulmonary and cardiac function and oxygen saturation measurements from breathing mask apparatuses. The device non-invasively monitors the physiologic profile of the subject, and is capable of detecting physiologic changes, predicting onset of symptoms, and alerting the wearer or another person or system. In some embodiments, the device comprises both a wearable sensor suite and a portable gas composition and flow analysis system. In preferred embodiments, it comprises a miniaturized non-invasive sensor suite for detecting physiologic changes to detect dangerous breathing or other health conditions. The acquired physiologic profile is used to generate alarms or warnings based on detectable physiological changes, to adjust gas delivery to the subject, alter mission profiles, or to transfer control of the craft or other duties away from a debilitated subject. The device is compact, portable, vehicle independent and non-encumbering to the subject.
US11524184B2	Topical skin care formulations comprising plant extracts A method for treating a person's skin is disclosed. The method includes topically applying to the skin a composition comprising from 0.001% to 20% by weight of an aqueous, alcoholic, or aqueous-alcoholic extract from a plant extract.
US11524183B1	System, apparatus, and method for delivering ultrasound A method can include placing a high intensity focused ultrasound (HIFU) probe proximate a first location of a designated treatment volume of a patient. The probe can include at least one transducer. The method can also include energizing the transducer to ablate a first lesion on or in the designated treatment volume, de-energizing the transducer, and focusing or moving the transducer to a second location on or in the designated treatment volume. The method can also include reenergizing the transducer to ablate a second lesion on or in the treatment volume, de-energizing the transducer, and focusing or moving the transducer to a third location on or in the designated treatment volume. The method can further include reenergizing the transducer to ablate a third lesion on or in the treatment volume, and de-energizing the transducer.
US11524177B2	Multi-leaf collimator and radiotherapy equipment A multi-leaf collimator includes a first carriage, a second carriage, a drive device, a first set of leaves disposed on the first carriage, and a second set of leaves disposed on the second carriage, wherein the first set of leaves and the second set of leaves are disposed oppositely to each other, and each leaf in each of the sets of leaves is movable relative to each respective carriage; and the drive device is configured to drive the first carriage and the second carriage to move in the same direction synchronously.
US11524174B2	Optical stimulation system with on-demand monitoring and methods of making and using An optical stimulation system includes a light source configured to produce light for optical stimulation; a light monitor; an optical lead coupled, or coupleable, to the light source and the light monitor; and a control module coupled, or coupleable, to the light source and the light monitor. The control module includes a memory, and a processor coupled to the memory and configured for receiving a request for verification or measurement of a light output value; in response to the request, receiving, from the light monitor, a measurement of light generated by the light source; and, based on the measurement, reporting a response to the request.
US11524168B2	Self-contained, connected automated external defibrillator systems and methods of use A self-contained automated external defibrillator (SCAED) system includes an AED operations block for controlling shock generation and administration, including pads for attachment to a patient, an electrocardiogram monitoring circuitry for monitoring patient heartbeat, shock generating electronics for generating electrical shock signal to be applied to the patient through the pads, a battery for supplying power to the AED operations block, a power management block for managing power consumption by the shock generating electronics and monitoring power status of the battery, a memory, a user-interface block for providing use instructions and receiving user input, and a controller for regulating the ECG monitoring circuitry, shock generating electronics, and the power management block. The SCAED system also includes a communications block for communicating with an external system separate from the SCAED system. The SCAED system further includes a security block for regulating data transfer between the AED operations block and the communications block.
US11524164B2	Apparatus for controlling an implantable medical device A system and methods of maintaining communication with a medical device for exchange of information, instructions, and programs, in a highly reliable manner. Apparatus and methods for accomplishing this task include: 1) The inclusion of a locating device in the system, in close proximity to an implanted device, but which does not drain the implanted device battery. The locating device may be implanted or external to the body. 2) The use of motion detection and global positioning system devices to locate elements within a communicating system for the medical device; 3) The assessment of received signal quality by elements of the system; 4) The use of a notification system for a device user who is moving out of range of communications; and 5) Documenting the absolute and functional integrity of instructions received by the medical device.
US11524157B2	Substernal leadless electrical stimulation system Implantable leadless cardiac pacing systems and methods for providing substernal pacing using the leadless cardiac pacing systems are described. In one embodiment, an implantable leadless cardiac pacing system includes a housing, a first electrode on the housing, a second electrode on the housing, and a pulse generator within the housing and electrically coupled to the first electrode and the second electrode. The housing is implanted substantially within an anterior mediastinum of a patient and the pulse generator is configured to deliver pacing pulses to a heart of the patient via a therapy vector formed between the first and second electrodes.
US11524155B2	Foraminal ligament anchor for application in DRG therapy In one embodiment, a system for stimulating the dorsal root ganglion of a patient comprises an elongate flexible implantable stimulation lead adapted to apply the stimulation pulses to the dorsal root ganglion of the patient, wherein the distal end comprises at least one electrode. A first segment and a second segment of the anchor are configured to transition between a collapsed configuration and deployed configuration. A central channel in the first segment and the second segment allows the anchor to be advanced along the stimulation lead from a proximal end toward the distal end while in the collapsed configuration. The central channel of each segment grips onto the stimulation lead in the deployed configuration so that the segment does not move from a deployed position on the stimulation lead. The first segment and the second segment may be deployed on opposite sides of foraminal ligament to anchor the stimulation lead.
US11524153B2	Mechanical circulatory support device with axial flow turbomachine optimized for heart failure and cardio-renal syndrome by implantation in the descending aorta Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, an intravascular propeller is installed into the descending aorta and anchored within via an expandable anchoring mechanism. The propeller and anchoring mechanism may be foldable so as to be percutaneously deliverable to the aorta. The propeller may have foldable blades. The blades may be magnetic and may be driven by a concentric electromagnetic stator circumferentially outside the magnetic blades. The stator may be intravascular or may be configured to be installed around the outer circumference of the blood vessel. The support may create a pressure rise between about 20-50 mmHg, and maintain a flow rate of about 5 L/min. The support may have one or more pairs of contra-rotating propellers to modulate the tangential velocity of the blood flow. The support may have static pre-swirlers and or de-swirlers. The support may be optimized to replicate naturally occurring vortex formation within the descending aorta.
US11524152B1	Valves and hubs for tubular devices and methods for making and using them A valve is provided for a sheath, catheter, or other tubular device that includes a first face, a second face opposite the first face and an axis extending between the first and second faces. A first slit extends substantially parallel to the axis from the first face towards the second face to a first intermediate location within the valve body, a second slit extends substantially parallel to the axis from the second face towards the first face to a second intermediate location within the valve body, and a bore extends along the axis between the first intermediate location and the second intermediate location.
US11524151B2	Apparatus, system and method for fluid delivery A filling aid. The filling aid includes a needle housing portion including at least one tab having a starting position and a filling position, and a filling needle cradle including a filling needle, the filling needle cradle slidable connected to the needle housing portion and having a starting position and a filling position, wherein when the at least one tab on the needle housing moves from a starting position to a filling position, the filling needle cradle slides from a starting position to a filling position, and wherein when the at least one tab on the needle housing moves from a filling position to a starting position, the filling needle cradle slides from a filling position to a starting position.
US11524147B2	Valve system for inflatable devices Valves and valve systems are provided that are useful for integration with inflatable indwelling medical devices to prevent over-inflation of retention balloon.
US11524146B2	Methods and devices for transcervical treatment of endometrial cancer and hyperplasia An infusion catheter includes a housing, a proximal shaft assembly, a first distal shaft assembly and a second distal shaft assembly. The housing has one or more inflation ports and one or more infusion ports. The proximal shaft assembly supports a first balloon. The first distal shaft assembly extends distally from the proximal shaft assembly and supports a first distal balloon. The second distal shaft assembly extends distally from the proximal shaft assembly and supports a second distal balloon. The first and second distal shaft assemblies define infusion openings in fluid communication with the one or more infusion ports. The infusion catheter may be inserted into a uterine cavity to occlude tubal ostia and an internal cervical OS of the uterine cavity for sealing the uterine cavity. A therapeutic agent may be delivered through the infusion catheter and into the sealed uterine cavity to treat the uterine cavity.
US11524142B2	Guide extension catheter Guide extension catheters and related methods are disclosed. A guide extension catheter can comprise an elongate tube member, a push member, and an external manipulation member. The push member can be eccentrically coupled relative to the tube member and extend proximally therefrom for slidably positioning the tube member within and partially beyond a distal end of a guide catheter. The manipulation member can be coupled to a proximal end of the push member, where the manipulation member can be configured to secure the guide extension catheter in place during use by attaching to an external object such that the tube member and push member remain stationary without user engagement.
US11524139B2	Catheter with active return curve An active return curve deflectable catheter includes an elongate member, a fixation member, a deflection assembly, and a pull wire. The fixation member is coupled to a distal portion of the elongate member. The deflection assembly includes a hub assembly coupled to a proximal end of the elongate member, a handle, and a control member. The pull wire extends from the control member through the hub assembly to the fixation member. The elongate member is configured to deflect from an initial configuration to a deflected configuration in response to a pull force applied to the pull wire by actuation of the control member in a first direction.
US11524133B2	Patient interface A patient interface for delivery of a supply of pressurised air or breathable gas to an entrance of a patient's airways includes a frame member, a cushion assembly provided to the frame member, and an anterior wall member repeatedly engageable with and disengageable from the cushion assembly. The frame member includes connectors operatively attachable to a positioning and stabilizing structure. The cushion assembly includes a seal-forming structure and a void defined by an anterior surface of the cushion assembly. The anterior wall member has a predetermined surface area to seal the void of the cushion assembly and form a gas chamber when the anterior wall member and the cushion assembly are engaged. The void of the cushion assembly is sized such that the patient's nose and/or mouth is substantially exposed when the anterior wall member is disengaged from the cushion assembly thereby improving breathing comfort of the patient.
US11524132B2	Adjustable ambient air-oxygen blender An apparatus having an adjustable ambient air-oxygen blender that adjustably mixes ambient air with an oxygen supply, especially where a size, diameter or flow rate of an orifice is mechanically adjustable so as to control a quantitative mixing function of the blender.
US11524130B2	Device, system and method for thermal capnography A device for measuring a concentration of a component in a target sample includes a flow chamber with a first channel that receives a reference sample having a known concentration of the component. The flow chamber also includes a second channel that receives the target sample having an unknown concentration of the component. A pump operates to pump the reference sample and the target sample at a same volume flow rate through the first and second channels, respectively. A thermal mass flow meter measures a thermal conductivity of the reference sample, a thermal conductivity of the target sample, or both.
US11524127B2	System and method for delivery of gas to a tissue A system for delivery of gas to a tissue, comprises: a first container containing the gas, an applicator having a distal end arranged to deliver the gas to the tissue, a second container containing a purging gas, and; and a flow control system for controlling flow of gas. The system also comprises a three-port valve having a first port for receiving the gas from the first container, a second port for receiving the purging gas from the second container, and a third port in fluid communication with the applicator. The valve is switchable between a first state at which the first port fluidly connects to the third port, and a second state at which the second port fluidly connects to the third port.
US11524122B2	Flexible modules for injection devices Implementations of the present disclosure are directed to a module for attachment to an injection device that includes a flexible carrier foil configured to be attached to a surface of the injection device independent of a geometry of the surface, at least one light emitting diode attached to the flexible carrier foil in a first position and configured to emit a light signal in a direction based on the first position through a transparent wall of the injection device, at least one photodiode attached to the flexible carrier foil in a second position relative to the first position, the at least one photodiode being configured to detect at least a portion of the light signal from a direction based on the second position and being configured to emit an electrical signal based on the light signal to a microprocessor, and wherein the microprocessor is configured to receive the electrical signal emitted by the photodiode and to determine the position of a stopper and the amount of the fluid within the injection device based at least in part on the electrical signal.
US11524121B2	Medicament delivery device A medicament delivery device includes a housing configured to receive a container of medicament and a piston rod moveable within the housing and configured to engage a container of medicament when received within the housing. The medicament delivery device further includes a position-sensing mechanism configured to detect the position of the piston rod within the housing. The position-sensing mechanism includes a first light source configured to emit light, a first sensor disposed proximate the first light source and configured to receive light emitted by the first light source, and a blocking member moveable between the first light source and the first sensor. The first sensor is configured to detect the light pattern received to determine the position of the piston rod within the housing.
US11524120B2	Dose control system for injectable-drug delivery devices and associated methods of use The present invention relates to a dose control system adapted for an injectable drug delivery device, the drug delivery device comprising a substantially elongate drug delivery body, at least one injectable drug held by the body, the body having a distal and proximal extremity, wherein the dose control system comprises three-dimensional magnetic field producing means for producing a magnetic field along three axes (x,y,z); magnetic field detection means configured to detect changes in at least the magnetic field produced by the three-dimensional magnetic field producing means; displacement detection means configured to measure a relative displacement or relative movement of the drug delivery device, and an integrated control unit, wherein the integrated control unit is connected to the magnetic field detection means, and to the displacement detection means, for processing information received from both the magnetic field detection means and the displacement detection means; wherein the three-dimensional magnetic field producing means is configured to effect a rotating coaxial displacement around, and along, a longitudinal axis of the drug delivery system; the magnetic field detection means are located along said longitudinal axis; and the three-dimensional magnetic field producing means is located at, or near, a proximal extremity of the body of the drug delivery device.
US11524113B2	Electrical information device for communicating information related to a medicament delivery An electrical information device configured to communicate information related to a medicament delivery performed by a medicament delivery device is presented. The device includes at least one information communication unit configured to communicate the information, and at least one power providing arrangement including at least one power source, at least one electrical switch and at least one switch lock member. The at least one switch lock member being configured to be movable in an axial direction from a first position to a second position by an axial movement of at least one triggering member of the medicament delivery device, to cause a change of state of the at least one electrical switch in the second position, thereby providing electrical power to the at least one information communication unit from the at least one power source, and to be locked in the second position, such that the change of state of the electrical switch is maintained.
US11524111B2	Epileptic seizure prevention or treatment via heart rate clamping We report a method of treating an epileptic seizure in a patient, comprising: detecting said epileptic seizure, based on body data from said patient; and reducing a flow of blood to a brain of said patient in response to said detected seizure; wherein said reducing is effected by: increasing the parasympathetic input to said patient's heart, such as by electrically stimulating a parasympathetic nervous structure, applying cooling energy to a sympathetic nervous structure, or administering a cholinergic or a sympatho-blocking agent to said patient. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.
US11524107B2	System, method, and apparatus for electronic patient care A system for electronic patient care includes a hub. The hub is configured to monitor a patient-care device. The sandbox may be configured to control access to at least one of a hardware resource and a software resource. The hub is further configured to identify the patient-care device and execute an application to monitor the patient-care device. The hub executes the application within the sandbox component such that the application accesses the at least one of the hardware resource and the software resource through the sandbox component. The hub may be further configured to control the patient-care device. The hub may be further configured to receive an identification from the patient-care device and download the application from a server associated with the identification. The hub may be further configured to receive an identification from the patient-care device and update the application from a server associated with the identification.
US11524106B2	Blockage detection in reduced pressure therapy Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a pump assembly and a wound dressing configured to be positioned over a wound. The pump assembly and the wound dressing can be fluidically connected to facilitate delivery of negative pressure to a wound via a fluid flow path. The system can be configured to efficiently deliver negative pressure and to detect and indicate presence of conditions, such as a blockage in a fluid flow path. Monitoring of the conditions can be performed by detecting a level of activity of a pump of the pump assembly.
US11524105B1	Nasal aspirator capable of effectively preventing backflow and control method thereof A nasal aspirator capable of effectively preventing backflow and a control method thereof are disclosed. The nasal aspirator includes a casing, a control board, a lower suction nozzle, an upper suction nozzle, a liquid storage cup, and an air pump unit. The control board is disposed in the casing. The lower suction nozzle is disposed on an upper end of the casing. The lower suction nozzle has a chamber and a suction passageway therein. The chamber has an opening facing upward. An upper end of the suction passageway communicates with the chamber. A detection system for detecting a liquid is provided in the chamber. The detection system is connected to the control board.
US11524099B2	Composition for acoustic wave probe, silicone resin for acoustic wave probe using the same, acoustic wave probe, ultrasound probe, acoustic wave measurement apparatus, ultrasound diagnostic apparatus, photoacoustic wave measurement apparatus, and ultrasound endoscope Provided is a composition for an acoustic wave probe including a polysiloxane mixture containing at least polysiloxane having a vinyl group and a phenyl group, polysiloxane having two or more Si—H groups in a molecular chain, and zinc oxide, a silicone resin for an acoustic wave probe, the acoustic wave probe, an acoustic wave measurement apparatus, an ultrasound diagnostic apparatus, an ultrasound probe, a photoacoustic wave measurement apparatus, and an ultrasound endoscope.
US11524094B2	Porous composite material The present invention relates to porous composite materials and objects such as 3D scaffolds, in particular to bioactive and bioresorbable scaffolds that can be transformed at body temperature.
US11524090B1	Photocatalytic load reduction to extend reactive media filtration life in an air purification system A process for using photocatalytic load reduction to extend reactive media filtration life is disclosed for an air purification system. The system consists of three methods of cleaning the air including a UV light, a photocatalyst, and an air purifier. Air first passes through a portion with the UV light and photocatalyst, and then through the purifier. Passing the air first through the UV light and photo catalyst before the purifier reduces the load on the purifier and thus allowing the purifier to operate and clean the air for an extended period of time as compared to the purifier alone.
US11524089B2	Hand wash cleaning and environmental purification diffuser A hand wash cleaning and environmental purification diffuser includes tank cover covered on a slot of a water tank in a bottom shell, a diffusing cover assembled to an opening of the bottom shell to shield the tank cover, an air flow channel formed in the oscillation space in the water tank and shaped like a tubular bulge so that when the diffuser is dumped, the liquid in the water tank is less likely to seep directly into the interior of the diffuser or the environment, two oscillators mounted in the oscillation space in the water tank and respectively coated with a layer of acid and alkali resistant coating, users can add safe cleaning liquids such as alkaline ionized water to the oscillation space and atomize into a cleaning mist, which can be used as deodorization and sterilization for hand cleaning, disinfection and environmental purification, and is safe to use.
US11524086B2	Proportionality of distributed illumination with adaptive multivector delivery system An ultraviolet emitting device comprising a plurality of light sources; and a plurality of arms on which the plurality of light sources are mounted, wherein: each arm is expandable between a first position and a second position, each arm is fully collapsed in the first position and fully expanded in the second position, and when each arm is transitioning between the first position and the second position, a length of the arm maintains a fixed proportionality with respect to a spacing of the plurality of light sources on the arm.
US11524085B2	Door handle sanitizing device A door handle sanitizing apparatus may include a posterior wall configured to be disposed anterior of and substantially parallel to a door surface and having an inner surface, an arch portion extending in an anterior direction from the posterior wall, the arch portion having an anterior end and an inner surface, a first sanitizing agent source disposed on the posterior wall, and a second sanitizing agent source disposed on the inner surface of the arch portion.
US11524083B1	Personal, portable, hand-held UV sanitizer and method of use A personal, portable, handheld UV light sanitizer (20) having a tubular housing (22) with a UV light source (32) for uniformly radiating a user's hand through a light transmittable outer wall (24) of the housing having a girth and length that enables substantially the entire the exterior surface of the outer wall to be covered by a user's hand when fully grasping the outer wall. A rearward annular wall (41) reduces any rearward light leakage and provides a bearing surface against which the edge of the user's hand may rest to prevent slippage. An annular forward wall (40) reduce forward light leakage and mounts actuation switches (36, 56), remote sensors (58, 60), a status indicator light (61) and an alarm speaker (59). When the skin surface sanitization mode switch (36) is actuated, skin sanitizing UV light radiation (42) radiates the inside of the user's hand for a preselected time period, unless there have previously been an excessive number of past hand sanitization cycles or too little time has passed since the last hand sanitization cycle (FIG. 9). Once energization, it is automatically deenergized after a preselected maximum time period (FIG. 9). Mounted to the front of the forward annular wall is another UV light source (51) that radiates UV light to suspect target surfaces spaced from the user's hand. A range finder (58) helps the user to hold the surface UV light source at the right distance from the target surface for effective sanitization, and energization is immediately terminated in response to an infrared sensor detecting that the surface UV light source is directed at a person's skin.
US11524080B2	Methods for the preparation of a pharmaceutical-vesicle formulation and associated products and uses The invention relates to methods for the preparation of a pharmaceutical-vesicle formulation comprising steps of: preparing and processing vesicle components and a pharmaceutical agent to entrap the pharmaceutical agent in the vesicle and form a pharmaceutical-vesicle formulation, wherein the pharmaceutical-vesicle formulation is reconstituted in a known quantity of the pharmaceutical agent dissolved in a pharmaceutically-acceptable carrier to provide a biphasic pharmaceutical-vesicle formulation. The invention also relates to the associated pharmaceutical-vesicle formulations, pharmaceutical kits and uses as a medicament, in particular for the prevention or treatment of infection by bacteria such as Burkholderia pseudomallei and Francisella tularensis, and viruses such as Venezuelan Equine Encephalitis Virus (VEEV).
US11524078B2	Water-soluble macromolecular derivative of Venetoclax The present invention aims at providing novel means for administering Venetoclax, wherein the means reduces the burden on a patient caused by taking Venetoclax and achieves a good balance between the effect and safety of Venetoclax. The present invention relates to a water-soluble macromolecular derivative that includes a plurality of Venetoclaxs, each Venetoclax being linked to a terminal carboxyl group of a multi-arm water-soluble polymer via an amide bond.
US11524077B2	Orally active, cell-penetrating homing peptide and methods using same Disclosed are compositions and methods useful for oral delivery of targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. The disclosed targeting is useful for oral delivery of therapeutic and detectable agents to diseased tissue in an animal.
US11524076B2	Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Steptococcus pneumoniae serotypes.
US11524074B2	Cancer-cell-specific anti-TMEM-180 monoclonal antibody, anticancer drug, and cancer testing method An object of the present invention is to provide an anticancer drug capable of treating cancer by finding a target molecule specifically expressed in cancer cells and by specifically acting on the target molecule, and to provide a cancer testing method including a step of measuring the target molecule in a sample. The present invention provides an anticancer drug containing, as an active ingredient thereof, an anti-transmembrane protein 180 (TMEM-180) antibody or an antigen-binding fragment thereof. In addition, the present invention provides a cancer testing method including a step of measuring the amount of TMEM-180 in a sample collected from a subject.
US11524072B2	Vaccine delivery method A vaccine delivery method is presented that includes a composition including as one component a slurry matrix that is a liquid at room temperature and a gel at physiological pH, physiological salt concentrations and/or physiological temperatures and as a second component one or more antigens. Also included are methods of inducing an immune response in a subject and vaccinating a subject by administering such compositions.
US11524071B2	Lipidated immune response modifier compound compositions, formulations, and methods The compound N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxy}butyl)octadecanamide is a useful drug compound for enhancing immune response and can be used, for example, as a coronavirus vaccine adjuvant.
US11524065B2	Large and small T antigens of merkel cell polyomavirus, nucleic acid constructs and vaccines made therefrom, and methods of using same Nucleic acid molecules and compositions comprising one or more nucleotide sequences that encode a consensus Merkel Cell Polyomavirus (MCV) T antigen. Immunomodulatory methods and methods of inducing an immune response against MCV are disclosed. Method of treating infection by MCV and methods of treating or preventing Merkel Cell Carcinoma associated with MCV are disclosed. Modified consensus MCV T antigens are disclosed.
US11524063B2	Materials and methods relating to immunogenic epitopes from human papillomavirus Embodiments of the present disclosure pertain generally to head and neck squamous cell carcinomas (HNSCCs) related to human papillomavirus subtype 16 (HPV16) infections. More particularly, the present disclosure provides novel immunogenic epitopes from HPV16 E2, E6 and E7 antigens restricted by common human leukocyte antigen (HLA) alleles for the diagnosis and treatment of HNSCC. The HPV16 epitopes identified in the present disclosure can be used in combination with blockade of HPV16+ HNSCC-specific checkpoints for targeted immunotherapy.
US11524062B2	Compositions and methods for treating cancer and promoting wound healing Protein complex variants, compositions, and methods of use thereof are provided. The protein complex variant includes a cholera toxin B subunit variant having one or more modifications thereto. The method of use thereof includes treating a disease by administering an effective amount of a composition including a cholera toxin B subunit variant to a subject in need thereof.
US11524061B2	Poultry vaccine for clostridium perfringens The present disclosure relates to nanoparticle compositions for use as vaccines against Clostridium perfringens in poultry which causes necrotic enteritis in poultry. Such compositions include one or more Clostridium perfringens extracellular proteins entrapped in a polyanhydride or chitosan nanoparticle. The one or more Clostridium perfringens extracellular proteins may include one or more Clostridium perfringens toxins, such as, for example, alpha toxin (CPA), beta toxin (CPB), epsilon toxin (ETX), iota toxin (ITX), perfringolysin O (PFO), enterotoxin (CPE), beta2 toxin (CPB2), or NetB toxin. In some aspects, the composition further includes a Salmonella enteritidis flagellar protein. The present invention also includes methods for the oral delivery of one or more Clostridium perfringens extracellular proteins to the mucosal membrane of the intestinal tract of a bird of the order Galliformes.
US11524057B2	Cysteine protease The present invention relates to a novel polypeptide which displays IgG cysteine protease activity, and in vivo and ex vivo uses thereof. Uses of the polypeptide include methods for the prevention or treatment of diseases and conditions mediated by IgG, and methods for the analysis of IgG.
US11524050B2	C3B binding polypeptide Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.
US11524049B2	Formulations and methods of use for alpha connexin c-terminal (ACT) peptides This invention relates to a topical gel drug product preparation containing a composition comprising an isolated polypeptide having a carboxy-terminal amino acid sequence of an alpha connexin (ACT peptide), peptide stabilizers, excipients, buffering agents, and the like. A formulation and preparation steps are disclosed for the manufacturing of a stable, elegant, and pourable topical gel. The resulting formulation possesses long term stability suitable for aesthetic as well as therapeutic applications including the prevention of scaring and accelerated healing of wounds. Methods for treatment of chronic wounds, including chronic ulcers, are also provided.
US11524046B2	Biofilm prevention, disruption and treatment with bacteriophage lysin The present invention provides methods for the prevention, control, disruption and treatment of bacterial biofilms with lysin, particularly lysin having capability to kill Staphlococcal bacteria, including drug resistant Staphylococcus aureus, particularly the lysin PlySs2. The invention also provides compositions and methods for use in treatment or modulation of bacterial biofilm(s) and biofilm formation.
US11524043B2	Composition including an immune modulator and adaptogens Therapeutic compositions for addressing physiological stresses and aging include an immune modulator and one or more adaptogenic nutrients. Some non-limiting examples of immune modulators include as transfer factor, low molecular weight fraction immune modulators and/or other low molecular weight fractions of colostrum, egg or any other source of transfer factor or low molecular weight fraction immune modulators. Methods for administering immune modulators and adaptogenic nutrients to a subject to address the effects of physiological stresses and aging in the body of the subject, such as inflammatory responses, are also disclosed.
US11524039B2	Topical compositions comprising extract of Coriolus versicolor for autoimmunity enhancement The present invention provides a topical composition comprising extract from Coriolus versicolor for use for preventing and/or treating by vaginal or cervical administration of a vaginal or cervical disorder which is caused by an infectious agent, in particular, human papiloma virus infections and related disorders, including cervical cancer. The composition of the invention acts enhancing genital immunity against infectious agents and re-epithelising damaged tissue.
US11524038B2	Methods for treating sarcopenia and maintaining or increasing muscle mass and muscle strength in elder subjects Disclosed herein is a composition including Lactobacillus plantarum TWK10 deposited at the China General Microbiological Culture Collection Center (CGMCC) under accession number CGMCC 13008 for use in treating sarcopenia and for use in maintaining and/or increasing muscle mass and/or strength in an elderly subject.
US11524030B2	Copolymers of hydrophobic and hydrophilic segments that reduce protein adsorption The present disclosure relates to compositions A composition comprising a polymerization product of an anionic polysaccharide, a diisocyanate, and a linker, wherein the linker comprises i) an ether group, an ester group, or a combination thereof and, ii) a chain extender comprising a hydroxyl group, a thiol group, an amine group, or a combination thereof. The disclosure further relates to medical devices comprising the aforementioned compositions, and to methods of using the compositions and devices. More particularly, the compositions, devices and methods described herein are useful for preventing protein adhesions in vivo, particularly the Vroman effect.
US11524029B2	Therapeutic composition and methods In exemplary embodiments, the disclosure provides a Colesevelam Colon Specific Drug Delivery System for use in treatment of, for example, cholestasis and/or cholestatic pruritus.
US11524027B2	Compositions of hyaluronan with high elasticity and uses thereof The present invention provides compositions comprising hyaluronan with high elasticity, as well as methods for improving joint function, reducing pain associated with joint function and treating osteoarthritis by introducing into a joint a therapeutically effective amount of a composition comprising hyaluronan with high elasticity.
US11524026B2	Heparanase inhibitors for treatment of diabetes Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
US11524023B2	Lipid nanoparticle compositions and methods of formulating the same Provided herein are compositions and methods of reducing adduct formation.
US11524021B2	Use of ginsenoside M1 for manufacturing medicament for treating oral cancer A use of ginsenoside M1 for manufacturing a medicament for treating oral cancer.
US11524019B2	Synthetic composition for reducing allergy symptoms This invention relates to a method and composition for inducing allergen tolerance in a patient suffering from an atopic allergy or allergic asthma; hence reducing allergy symptoms in these patients.
US11524018B2	Nutritional formulations including human milk oligosaccharides and antioxidants and uses thereof Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
US11524016B2	Compositions and methods for the topical administration of spironolactone for the treatment of cutaneous signs of excess androgen and chronic stress response The present disclosure provides methods for treating or alleviating symptoms of a disease, disorder, or condition related to excess androgen or stress-induced skin changes in a subject in need thereof by topically administering a pharmaceutical composition comprising a pharmaceutically effective amount of spironolactone to the subject. Other aspects relate to methods for providing anti-oxidative stress, anti-inflammatory and anti-aging benefits for the skin to a subject in need thereof by topically administering a pharmaceutical composition comprising a pharmaceutically effective amount of spironolactone to the subject. Surprisingly, it has been found that spironolactone may be topically administered with reduced adverse effect compared to systemic administration of the same medication.
US11524010B2	Substituted quinazoline sulfonamides as thioredoxin interacting protein (TXNIP) inhibitors In one aspect, compounds and compositions that inhibit TXNIP expression and/or that lower hepatic glucose production and methods of identifying, making, and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with elevated TXNIP and/or elevated glucagon levels such as, for example, diabetes and associated disorders. Further provided are methods for treating hyperlipidemia or fatty liver disease, optionally associated with elevated TXNIP and/or elevated glucagon levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US11524006B2	Crenolanib for treating TRK kinase associated proliferative disorders The present invention includes methods for treating TRKA, TRKB, and/or TRKC driven proliferative disorder in a subject comprising administering to the subject a therapeutically effective amount of crenolanib, wherein the subject has a proliferative disorder with overexpression, activation, amplification, or mutation of TRKA, TRKB, and/or TRKC kinase.
US11524004B2	Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same Peroxisome proliferator activated receptor (PPAR) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.
US11524002B2	Oxazolidinone for treatment of infections with Mycobacterium tuberculosis The present invention is a method of treating or preventing Mycobacterium tuberculosis infection in a subject by administering to the subject an effective amount of oxazolidinone, specifically (N—(((S)-3-(dibenzo[b,e][1,4]dioxin-7-yl)-2-oxooxazolidin-5-yl)methyl)acetamide) or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof.
US11523998B2	Anti-inflammatory formulations and uses thereof including a combination of palmitoylethanolamide and plant-based polyphenols Pharmaceutical or nutraceutical formulations are provided for treating inflammation in a subject in need thereof, as well as methods of treating inflammation in a subject in need thereof by administering one of the formulations. In some aspects, the pharmaceutical or nutraceutical formulation includes an effective amount of (i) palmitoylethanolamide or a derivative thereof, and (ii) one, two, three or more different small-molecule polyphenols or derivatives thereof to alleviate one or more causes or symptoms of the inflammation in the subject. In some aspects, the formulations include all three, e.g. the formulations includes (i) palmitoylethanolamide or a derivative thereof, (ii) quercetin or a derivative thereof, and (iii) curcumin or a derivative thereof. In some instances, the components (i)-(iii) discussed above are present at a mass ratio of about (i) 4 mg to 6 mg of palmitoylethanolamide or a derivative thereof to (ii) about 0.5 to 2.5 mg curcumin or a derivative thereof, and (iii) about 0.5 mg to 1.5 mg quercetin or a derivative thereof.
US11523997B2	Method of providing celiprolol therapy to a patient The present disclosure relates to the field of treatment of an orphan disease, in particular treatment of vascular Ehlers-Danlos syndrome (vEDS). More specifically, the present disclosure relates to novel up-titration dosage regimens (e.g., escalating dosage regimens) effective for treating vEDS patients with celiprolol.
US11523996B2	Extended release liquid compositions of metformin The present invention relates to extended release liquid compositions of metformin. The extended release liquid compositions are in the form of suspensions or reconstituted powder for suspensions. Said extended release liquid compositions comprise cores of metformin coated with a release-controlling agent, wherein the coated cores are dispersed in a suspension base. Said extended release liquid compositions provide the desired uniform extended release profile throughout the shelf-life of the composition. Furthermore, said extended release liquid compositions are bioequivalent to a reference composition. It also relates to processes for the preparation of said extended release liquid compositions.
US11523987B2	Trimcinolone and moxifloxacin methods Provided here are new ophthalmological methods for the treatment or prophylaxis of ocular bacterial infections and related conditions comprising delivering an effective amount of an ophthalmologically suitable composition comprising an effective amount of a moxifloxacin compound and an effective amount of a triamcinolone compound. In aspects, methods comprise delivery of the composition by injection. In aspects, the delivered compositions are stable suspensions, which maintain physical stability and chemical stability for extended periods of time (e.g., exhibiting no sustained flocculation, coagulation, or clumping after several months of storage under typical storage conditions). In aspects, compositions are suspensions that include a suspension component comprising one or more suspension agents. In aspects, the suspension component includes an ionic suspension and may also or alternatively comprises a non-ionic surfactant, non-ionic suspension agent, or both, or, an agent that provides both functions. In aspects, such compositions further comprise an effective amount of a chelating agent.
US11523986B2	Intranasally administered antihistamines and uses thereof Disclosed herein are compositions including diphenhydramine, or a pharmaceutically acceptable salt thereof, and a liquid vehicle. The compositions may be administered intranasally to patients in need of diphenhydramine. The compositions provide increase plasma and brain concentrations relative to orally administered compositions, but without the limitations associated with intravenously administered compositions.
US11523985B2	Formulations, methods, and systems for treating genitourinary conditions Provided are formulations and methods for treating one or more genitourinary conditions. The formulations may include a therapeutic agent that includes a calcium channel blocker, a rho kinase inhibitor, or a combination thereof. The methods may include locally administering a therapeutic agent into a ureter. Systems for delivering a therapeutic agent also are provided.
US11523984B1	Compositions and methods of administering baclofen Injectable baclofen formulations and methods that are bioequivalent in terms of plasma baclofen exposure to oral dosage forms but with reduced exposure ratios of baclofen to the M1 metabolite.
US11523982B2	Marine extract compositions and methods of use Compositions comprising extracts from marine organisms show beneficial effects on skin ailments. Fine lines, wrinkles, and sagging in skin are improved with the application of compositions with marine extracts. Production of collagen, elastin and hyaluronic acid are increased after application of the compositions.
US11523977B2	Multi-agent type hair treatment agent A multi-agent type hair treatment agent comprising a first composition containing component (A) and component (B); and a second composition containing component (C), wherein the weight ratio (H)/(C) of component (H) to component (C) in the second composition is less than 1. A hair treatment method comprising the steps of applying and rinsing the first composition to hair (i) and then applying the second composition to hair (ii). Component (A): a carboxylic acid having an inorganic value of 230 or more and 450 or less and an organic value of 50 or more and 250 or less, or a salt of the carboxylic acid Component (B): anionic surfactant Component (C): an aromatic sulfonic acid having a molecular weight of 300 or less or a salt thereof Component (H): cationic surfactant.
US11523974B2	Apparatus and method for continuous monitoring of gastric content volume A method and apparatus for determining gastric content volume. The internal temperature of the contents of the stomach is measured at least one predetermined time t after the patient is fed, and the gastric volume determined from the temperature. In preferred embodiments, a known volume of water at a known temperature is injected into the stomach, and the temperature of the stomach contents is measured after the stomach temperature has stabilized. An apparatus for performing the method, in which continuous measurement is possible without disturbing the patient's feeding schedule, and a method for using the inventive method in the control of an automatic feeding apparatus, are also disclosed.
US11523969B2	Apparatus and methods for sealing a medicament within a medical delivery device Apparatus and methods for lyophilizing and sealing a medicament within a medical delivery device having an opening. The apparatus may include a stopper for sealing the opening. The stopper may have one or more elongated members extending from a base, in a direction that is parallel to a central axis of the base. One or more of the members may be set radially away from the axis and define a coaxial central well. The member or members may define a void. The elongated member or members may engage a device inner wall and support the base away from the opening. The void may provide gas exchange between a device interior and a device exterior. The gas may be a lyophilization byproduct that escapes from the device interior between the inner wall, the base and the member or members. The stopper may be advanced into the device to seal the opening.
US11523966B2	CPR chest compression system In embodiments, a CPR chest compression system includes a retention structure that can retain the patient's body, and a compression mechanism that can perform automatically CPR compressions and releases to the patient's chest. The compression mechanism can pause the performing of the CPR compressions for a short time, so that an attendant can check the patient. The CPR system can include a user interface that can output a human-perceptible check patient prompt, to alert an attendant to check the patient during the pause. The compression mechanism can during a CPR session retreat a distance away from the patient's chest whereby the patient's chest can expand without active decompression of the patient's chest beyond the chest's natural resting position.
US11523964B2	Sexual stimulation device Disclosed embodiments provide an improved stimulation device for sexual gratification. An enclosure includes a moveable shaft in a phallic shape, and a vibration surface located near the base of the shaft. The arrangement allows the shaft to be inserted in the vagina of a user while the vibration surface is in contact with the clitoral region of the user. In embodiments, the enclosure comprises two concave sides and a convex opposing surface. The concave side surfaces are well suited to accommodate the legs of a user. The convex opposing surface enables a rocker mode of operation in which the user places the device on a floor surface such that the convex opposing surface is on the floor, and then straddles the device, enabling a rocking motion during stimulation, which can create an enhanced user experience.
US11523962B2	Positionable foot portion of a medical device The object of the invention is a foot portion (2a) of a medical device, such as gynecological examination bed or a birthing bed. The aim of the invention is to provide a method for moving the foot portion into the required position quickly, effectively and not limiting the actions of medical personnel. An advantage of the present invention is moving the foot portion under the rest area (1) without undesirable protrusion. Movement of the foot portion (2a) under the rest area (1) is performed around a column (5), which is attached under the side edge of a seating portion (3). Such arrangement of the column leaves free space under the rest area (1) for moving the foot portion (2a). Movement of the foot portion (2a) is performed with minimum protrusion over the borderline of the rest area (1) by means of a parallelogram. The foot portion according to the present invention may be also positioned horizontally and vertically, according to the patient's need during the procedure. For each movement, there are available separate moving mechanisms and latching mechanisms.
US11523961B1	System, device and method for stable airway management Embodiments of a device facilitate controlled positioning and manipulation of an individual's relative head, neck and jaw positions to facilitate stable airway management. In various embodiments, the device includes a base to which support arms are movably attached. A thrust arm is movably attached to each support arm and a jaw disc is attached to each thrust arm and adapted for rotation in accommodating various shapes and sizes of patient jaws.
US11523960B2	Relocation module and methods for surgical equipment An anesthetic equipment storage and waste air management module configured to housing electronic and electromechanical surgical equipment including a system to measure and record administration of one or more IV medications or fluids for IV administration. The module can include a housing having a lower section and a tower-like upper section, wherein the lower section is configured to house unrelated waste heat-producing electronic and electromechanical surgical equipment. The module can also include a cowling that substantially confines waste heat generated by the unrelated waste heat-producing electronic and electromechanical surgical equipment, and can include a system for measuring and recording the administration of the one or more IV medications and fluids.
US11523957B2	Patient transfer system Disclosed is a patient transfer system for transferring a user between a bed and a purposefully designed mobile sitting device that is aligned and berthed alongside the bed, wherein, the bed is adaptable to a seated arrangement and includes an interleaf structure of cushions and platforms, the platform including: a padding, a rail, restricted path, or track, and means for transferring the padding in a direction parallel to the ground away or towards the bed; the bed further includes means to raise or lower the top of the cushions or the padding; and the mobile sitting device includes a receiving rail, restricted path or track to receive the padding.
US11523956B2	Patient support apparatus transport handle A patient support apparatus includes a frame. A vertical transport structure may be coupled with the frame. A grip is coupled with the vertical transport structure and at least one grip sensor is coupled to the grip on the vertical transport structure. A controller determines a vertical position of a user applied force applied to the at least one grip sensor and the controller activates a power drive mode upon determining that the push force has reached a threshold value corresponding to the vertical position of the user applied force and propel patient support apparatus.
US11523952B2	Input devices for controlling a wheelchair A system for controlling a wheelchair is disclosed. The system includes an input device that includes a shaft element, a base element, and one or more annular elements. A lower distal end of the shaft element is coupled to the base element, and the shaft element is configured to pivotally move about the lower distal end of the shaft element. A first annular element of the one or more annular elements is circumferentially disposed around the shaft element. The first annular element is coupled to the base element, and the first annular element is configured to rotate about the shaft element. The input device is configured to generate one or more input signals based on a position of the first annular element and a pivotal movement of the shaft element. The one or more input signals are configured to cause a controller to set an operation mode of the wheelchair.
US11523951B2	Portable power assist for manual wheelchairs Apparatus and associated methods relate to a wheelchair power assist device configured to switch a motorized friction roller between engaged and disengaged modes with a wheelchair wheel, based on an engagement actuator configured to move the friction roller relative to an attachment member removably secured to the wheelchair. The friction roller may be operably coupled with an engagement member configured to move relative to the attachment member. The engagement member may be moved by an extendable and retractable actuator shaft coupled with the attachment member. A manual wheelchair may be converted to a powered wheelchair using a motorized friction roller for each wheelchair wheel. A plurality of power assist devices may be configured to position a respective plurality of friction rollers to leave an open space behind the wheelchair seating area, advantageously permitting the power assist devices to remain attached to a foldable wheelchair in either folded or unfolded configurations.
US11523944B2	Topsheets integrated with heterogenous mass layer An absorbent article and method of making the absorbent article are disclosed. The absorbent article having a topsheet, a backsheet, and an absorbent core structure having one or more layers wherein at least one layer is a heterogeneous mass layer, wherein the topsheet and the heterogeneous mass are integrated such that they reside in the same X-Y plane.
US11523942B2	Medical suction tool for a Eustachian tube A method includes inserting into a patient body a medical suction tool, which includes a hollow first tube for removing material away from a Eustachian tube of a patient, and a hollow second tube disposed around the first tube. The medical suction tool is navigated to the Eustachian tube. The Eustachian tube is sealed by coupling an outer surface of the second tube to an inner surface of the Eustachian tube. While the Eustachian tube is sealed by the second tube, the material is removed away from the Eustachian tube via the first tube.
US11523941B2	Devices for application of localized hypothermic therapy to the human ear A heat transfer device particularly structured for application of thermal therapy from a contact surface to a human ear. A device may be passive (pre-cooled), active (thermoelectrically active), or include elements of both. A device may be structured to apply thermal treatment from a contact surface of a contact cavity only to a localized posterior area relative to the circumference of an ear. Preferably, a device provides an uninterrupted opening extending in a line-of-sight between an ear canal and the local environment. A device may include both of a contact cavity and a bulk cavity, with heat transfer media disposed in each cavity. Typically, a bulk cavity holds at least twice the media volume contained in a contact cavity. The cavities may be disposed in fluid communication, or separated by a barrier to permit only thermal communication there-between. When a barrier is present, a device may include different heat transfer media in each cavity. One or more device may be associated with various mounting structure to dispose a contact surface in contact with desired portion(s) of a head.
US11523939B2	Miniature fixed and adjustable flow restrictor for the body A microfluidic flow restrictor that uses micron-sized beads to impede flow is described. The flow rate can be adjusted by adding or removing the beads using injection needles through self-sealing ports, one injection needle injecting or aspirating beads and another injection needle pushing or pulling fluid from outside of a bead trap within the flow restrictor. In alternative embodiments, the beads or other filler material can be trapped in a manifold bead trap such that they block a subset of fluid channels of the flow restrictor, allowing fluid to flow freely through the rest of the fluid channels. The flow restrictor can be integrated with a contact lens or implantable medical device for use in dispensing liquid therapeutic agents at flow rates of microliters per minute or moving body fluids at a controlled rate from one part of the body to another.
US11523938B2	Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with a suprachoroidal space of the eye. The implant can drain fluid from an anterior chamber of the eye to a physiologic outflow path of the eye, such as, the suprachoroidal space or other portion of the uveoscleral outflow path. The delivery or inserter devices or systems can be used in conjunction with other ocular surgery, for example, but not limited to, cataract surgery through a preformed corneal incision, or independently with the inserter configured to make a corneal incision. The implant can be preloaded with or within the inserter to advantageously provide a sterile, easy-to-use package for use by an operator.
US11523934B2	Method and system to facilitate the growth of desired bacteria in a human's mouth A method to facilitate the growth of desired bacteria in a human's mouth by using a bioadhesive strip that has an encapsulated feature containing at least one bacteria that has one of a pathogenic or toxic element excised using a clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR associated protein (Cas) system or a CRISPR from Prevotella and Francisella 1 (Cpf1) system, and in particular, using oral strips that adhere to surfaces in the oral cavity and that include at least one of xylitol, Lachnospira, Veillonella, Faecalibacterium and/or Rothia bacteria.
US11523932B2	Enteric fistula, rectovaginal fistula, and ostomy effluent containment system, and devices and methods thereof A skin-safe effluent containment system that may be used to contain fluid leakage from openings in the body of a patient and will adhere to skin in any condition: healthy or injured, wet or dry, smooth, scarred, or uneven. Fluid leakage can occur from natural orifices such as the anus and vagina, spontaneously formed enteric fistulas, rectovaginal fistulas, and surgical openings such as ileostomy and colostomy stomas. The system includes a vacuum-adherent pouch device, comprised of a pouch connected to a porous foam ring which has an air-permeable contact layer on its bottom surface and an air seal on its top surface. The inner and outer perimeters of the foam ring are enclosed and sealed with skin-adhesive materials. When placed on the patient, negative pressure (vacuum) is applied to the foam ring so that the foam collapses and compresses the vacuum-adherent pouch device down against the patient's skin. Negative pressure in combination with the adhesive materials on the perimeters of the foam ring forms a fluid barrier around the opening in the body of the patient so that leakage can be directed into the pouch and drawn away to a separate effluent container.
US11523929B2	Accessory device, a patient immobilization system, and a method of forming a patient immobilization system An accessory device and an immobilization system including the device are provided for positioning at least a portion of a patient's body relative to an immobilization device including a low temperature thermoplastic sheet. The accessory device may include a patient fixation portion and a lock portion. The patient fixation portion is attached to or inserted in the patient during use. The lock portion may extend distally from the patient fixation portion generally along a lock portion axis. The lock portion includes a shape, surface feature, or configuration, such that the low temperature thermoplastic sheet may be conformed to the outer surface of the lock portion of the accessory device, such that unintended separation of the accessory device from the low temperature thermoplastic sheet is prevented. Methods of forming the accessory device and immobilization system are also provided.
US11523919B2	Stent The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by “open” cells and at least two end portions, defined by “closed” cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings.
US11523916B2	In-situ additive implants Methods for growing spinal implants in situ using a surgical additive-manufacturing system. In one aspect, the method includes positioning a dispenser at least partially within an interbody space, between a first patient vertebra and a second patient vertebra. The method includes maneuvering the dispensing component within the space to deposit printing material forming an interbody implant part, positioning the dispensing component adjacent the vertebrae, and maneuvering the dispenser adjacent the vertebrae to deposit printing material on an exterior surface of each vertebrae and in contact with the interbody implant part forming an extrabody implant part connected to the interbody implant part and vertebrae, yielding the spinal implant grown in situ connecting the first vertebra to the second vertebra. The extrabody part can be printed around anchors affixed to the vertebrae, and the anchors may be printed in the process.
US11523911B2	Glenoid adapter for shoulder joint prosthesis The present invention relates to an improved glenoid adapter for shoulder prostheses, in particular for the conversion of an anatomic resurfacing prosthesis to a reverse shoulder prosthesis, comprising: •—at least one fixing projection (2) having an own axis (X) and being arranged to be fixed to the glenoid cavity (301) of the scapula (300) •—a flange (4) integral with said fixing projection (2); •—an attachment portion (3) integral with the flange (4) and extended in the direction opposite said fixing projection (2), as well as arranged to be coupled with an articular component (10) of reverse prosthesis provided with a convex articular surface (11), said attachment portion (3) having an own longitudinal axis (Y); both the fixing projection (2) and the attachment portion (3) have truncated-cone shape and that the axis of the attachment portion (Y) is misaligned with respect to the fixing projection axis (X); said flange (4) has a glenoid surface (4a) from which said fixing attachment (2) rises.
US11523909B2	In-situ additive implants An in-situ additive-manufacturing system for growing an implant in-situ for a patient. The system has a multi-nozzle dispensing subsystem and a distal control arm. The multi-nozzle dispensing subsystem in one embodiment includes first and second dispensing nozzles. The first and second nozzles include first and second printing-material delivery channels, respectively. In another embodiment, the in-situ additive-manufacturing system includes a multi-material subsystem having a dispensing nozzle including first and second printing material delivery channels. Controlling computing and robotics componentry are provided. In various aspects, respective storage for first and second printing materials, and one or more pumping structures, are provided.
US11523903B2	Delivery catheter system with micro and macro movement control A tray and packaging system for a prosthetic valve delivery system permits conversion from a storage and/or shipping configuration to a set up and preparation configuration. In a first configuration, a delivery system can be supported by first and second main trays with the elongate catheter of the delivery system arranged to extend linearly from the first main tray to the second main tray, and in a second configuration, the delivery system can be supported by the first and second main trays with the elongate catheter of the delivery system turned back in a U-shaped manner with the deployment portion of the delivery system positioned to the side of the control handle portion of the delivery system.
US11523902B2	Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves Apparatus and methods are described herein for use in the delivery and deployment of a prosthetic mitral valve into a heart. In some embodiments, an apparatus includes a catheter assembly, a valve holding tube and a handle assembly. The valve holding tube is releasably couplable to a proximal end portion of the catheter assembly and to a distal end portion of the handle assembly. The handle assembly includes a housing and a delivery rod. The delivery rod is configured to be actuated to move distally relative to the housing to move a prosthetic heart valve disposed within the valve holding tube out of the valve holding tube and distally within a lumen of the elongate sheath of the catheter assembly. The catheter assembly is configured to be actuated to move proximally relative to the housing such that the prosthetic valve is disposed outside of the lumen of the elongate sheath.
US11523901B2	Systems for placing a coapting member between valvular leaflets The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve or tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. A proximal anchoring feature fixes the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.
US11523898B2	Accommodating intraocular lens and methods of implantation An accommodating intraocular lens device for treatment of an eye having a lens body; internal support; stabilization system; and force translation arm. The lens body includes an accommodating membrane, an annular element, a static element, and a fixed volume of optical fluid filling a sealed chamber of the lens body. The annular element coupled to the perimeter of the accommodating membrane has a shape deformation membrane configured to undergo displacement relative to the perimeter region. The sealed chamber is formed by inner surfaces of the accommodating membrane, shape deformation membrane, and static element. The force translation arm has a first end operatively coupled to the shape deformation membrane and a free end available and configured to engage a ciliary structure of the eye. The force translation arm is moveable relative to the lens body to cause inward movement of the shape deformation membrane. Related methods, devices, and systems are provided.
US11523896B2	Ocular protection ring A device for reducing the incidence of surgical debris migration within a mammalian eye comprising an anterior portion, the anterior portion with an anterior inner surface and an opposing anterior outer surface, the anterior inner surface and the anterior outer surface terminating at an anterior edge that defines an open anterior end; and a posterior portion, with a posterior inner surface and an opposing posterior outer surface, the posterior inner surface and the posterior outer surface terminating at a posterior edge, the posterior edge defining an open posterior end; and a waist connecting the anterior portion and the posterior portion, the waist comprising a waist inner surface and an opposing waist outer surface; and an aperture extending from the open anterior end, through the waist, and to the open posterior end, the aperture bounded by the anterior inner surface, the waist inner surface, and the posterior inner surface.
US11523888B2	Ceramic dental restorations made by additive manufacturing An additively manufactured dental crown with a wall having a bottom edge and an occlusal portion joined with the wall opposite the bottom edge. The wall and occlusal portion form an interior surface and an opposing exterior surface. By using additive manufacturing and materials for such, the dental crown can have thin walls with a thickness of less than 300 microns at the thinnest portion of it and can include fine printed features such as identifiers, internal ribs, slots, porous meshes, and retention elements.
US11523885B2	Mounting system that maintains stability of optics as temperature changes A scanner for scanning a dental site comprises a base, a detector mounted to the base, and an optical element to redirect light reflected off of the dental site towards the detector along a detection axis in a first direction. Two or more flexures couple the optical element to the base, wherein thermal expansion or contraction of the optical element with respect to at least one of the detector or the base bends each flexure of the two or more flexures in a respective second direction without bending the flexure in a respective third direction approximately perpendicular to the first direction and the respective second direction, wherein the two or more flexures maintain an alignment of the optical element to the detector with changes in temperature.
US11523881B2	Prediction of aligner progressive damage using simulation Embodiments relate to an aligner breakage solution that tests progressive damage to an aligner. A method includes gathering a digital model representing an aligner for a dental arch of a patient, and simulating progressive damage to the aligner. Simulating progressive damage for a region of the aligner comprises simulating, using at least the digital model, a sequence of loads on the aligner, determining an amount of damage to the region of the aligner for each load, and after each simulation of a load on the aligner, updating the digital model based on the amount of damage to the region of the aligner. The method further includes determining whether a damage criterion is satisfied for at least one region of the aligner and determining whether to implement one or more corrective actions for the aligner.
US11523880B2	Instrument for drilling dental root canals An endodontic instrument that includes a tapered rod, the rod including an active portion and a distal end, the active portion defining an envelope having a longitudinal axis that coincides with an axis of rotation of the instrument.
US11523879B2	Handle systems and methods for endodontic tools A handle system for supporting a tool defining a tool axis during the performance of dental procedures comprises a handle defining a handle axis, a rotation sleeve, a head assembly and a gear set comprising first and second gear portions. The rotation sleeve supports the first gear portion. The head assembly supports the second gear portion. The handle supports the rotation sleeve for rotation relative to the handle. The handle supports the head assembly such that the first gear portion engages the second gear portion. With the head assembly supported by the handle, the head assembly engages the tool to support the tool such that the tool axis extends at a first angle relative to the handle axis and rotation of the rotation sleeve relative to the handle causes axial rotation of the tool about the tool axis.
US11523877B2	Position adjustment apparatus for adjusting position of detection device and magnetocardiography instrument A position adjustment apparatus for adjusting a position of a detection device, and a magnetocardiography instrument are provided. The position adjustment apparatus includes: two support assemblies, a lifting frame, and at least one height adjustment assembly. The position adjustment apparatus of the present disclosure enables free control over the height of the lifting frame by providing support rods and the height adjustment assembly comprising a pulley block.
US11523875B2	Enhanced catheter navigation methods and apparatus Methods, apparatus, and systems are provided for facilitating the navigation of a catheter between first and second locations within a subject based on display of serial images corresponding to positions of the catheter at successive incremental times. Image production includes sensing catheter positions to produce location data for each time increment. For each position Pi, the corresponding location data is processed to respectively produce an image Ii reflecting the position of the catheter at a time Ti. Each image Ii is successively displayed at a time equal to Ti+d, where d is an image processing visualization delay. Upon a condition that the catheter is displaced to a selected interim location between the first and second locations, the processing of the location data is switched from being performed by a first process associated with a first visualization delay to a second process associated with a second different visualization delay.
US11523874B2	Visualization of depth and position of blood vessels and robot guided visualization of blood vessel cross section A system for visualizing an anatomical target includes an imaging device (105) configured to collect real-time images of an anatomical target. A three-dimensional model (136) is generated from pre- or intra-operative images and includes images of structures below a surface of the anatomical target not visible in the images from the scope. An image processing module (148) is configured to generate an overlay (107) registered to the real-time images and to indicate the structures below the surface and a depth of the structures below the surface. A display device (118) is configured to concurrently display the real-time images and the overlay.
US11523866B2	Multi-carrier ablation generator A multicarrier ablation system comprising: an antenna for application to biological tissue; a multi-carrier signal generator configured to provide a forward radio frequency (RF) signal to the antenna, the forward RF signal comprising multiple subcarriers that occupy respective frequencies within a bandwidth of the RF signal; and a monitoring circuit configured to receive a reflected RF signal from the antenna and control the multi-carrier signal generator to adjust one or more parameters of the forward RF signal during an ablation procedure based on the reflected RF signal.
US11523862B2	Surgical forceps A forceps includes an end effector assembly having first and second jaw members movable between a spaced-apart position and an approximated position for grasping tissue therebetween. A knife assembly having a cutting blade disposed at a distal end thereof is also provided. The knife assembly is translatable relative to the end effector assembly between a retracted position and an extended position, wherein the cutting blade extends between the jaw members to cut tissue grasped therebetween. The knife assembly includes a proximal component and a first distal component that includes the cutting blade. The proximal and first distal components are removably coupled to one another to facilitate replacement of the first distal component. Methods of preparing such forceps for reuse are also provided.
US11523861B2	Methods for manufacturing a jaw assembly for an electrosurgical forceps A method of assembling a jaw member of an electrosurgical forceps includes aligning in vertical registration an electrically conductive seal plate, an insulative spacer and a jaw support. The method further includes stacking the seal plate atop the insulative spacer and the jaw support such that a flange depending from the seal plate seats within a corresponding cavity defined within a flange depending from the insulative spacer which, in turn, seats within a cavity defined within the jaw support. The method further includes mechanically securing the seal plate, insulative spacer and jaw support to one another and securing a jaw housing to surround the jaw support, the insulative spacer and the seal plate.
US11523858B2	System and method for RF ablation with generated images of ablated tissue lesions The invention includes a system for generating virtual images of proposed and designated areas on a patient's anatomy that are to be treated in a RFA procedure. The images include a size, shape, and location of lesion/ablation patterns. The virtual images include dynamic (developing) or static (developed) lesions selected for the RFA procedure. The images are provided on at least one user interface that superimposes or overlays the lesion pattern(s) on an image of a patient's anatomy that undergoes the procedure. The images can be used to accurately and efficiently conduct RFA procedures and to record the procedures with enhanced visual data to confirm treated tissue areas. The invention further includes a diagnostic method of generating images in preparation for a RFA procedure, and a method of conducting the RFA procedure in which measured parameters determine the size and shape of the ablated areas achieved in the procedure.
US11523857B2	Multiplexing algorithm with power allocation A system and method for use with an electrosurgical system for delivering energy to tissue wherein the system includes a generator having a maximum power, at least two channels, and a plurality of probes. The method includes a control system allocating power proportionally to the plurality of probes whereby the probes reach a predetermined threshold without significant delays.
US11523854B2	Driver and system for threaded intramedullary nail retaining endcaps A driver for engaging an endcap of an intramedullary nail. The driver includes a handle extending along a longitudinal axis of the driver from a proximal end to a distal end. The handle having a handle channel extending longitudinally therethrough. The driver also includes a shaft extending through the handle channel from a proximal end to a distal end along the longitudinal axis. The shaft having a shaft channel extending longitudinally therethrough. The distal end of the shaft extends distally from the handle. The distal end of the shaft forms a driving element to be inserted into a head portion of the endcap. The driver further includes a retention pin slidably received in the shaft channel. The retention pin extends also extends along the longitudinal axis. The distal end of the retention pin is configured to reversibly lock the shaft to the head portion of the endcap.
US11523853B2	Method and apparatus for fixation The present disclosure relates to fixation devices. Certain embodiments provide a fixation device for insertion into bone. The fixation device includes a body comprising threads along an outer surface of the body. The fixation device includes one or more blades movably coupled to the body. The one or more blades are configured to move between at least a first position and a second position. In the first position, the one or more blades are retracted into the body. In the second position, the one or more blades are deployed out of the body for insertion into the bone.
US11523852B1	Active compression bone screw A first bone portion may be secured to a second bone portion by forming a hole in the first bone portion and the second bone portion and inserting a bone screw into the hole. The bone screw may have a proximal member, a distal member, and a tension member with a proximal end coupled to the proximal member and a distal end coupled to the distal member. Torque may be applied to the bone screw to move the distal member away from the proximal member such that the tension member elongates and urges the distal member to move toward the proximal member. The torque may be transmitted from the proximal member to the distal member via a torque transmission feature. A bending transmission feature, displaced proximally or distally from the torque transmission feature, may be positioned to share bending loads between the proximal member and the distal member.
US11523851B2	Expandable osseointegration bone fixation apparatus for use in a variety of settings A cortical shaft bone fixation apparatus includes a housing having a leading portion and a trailing portion, the leading portion configured to fit within a diameter of an affected cortical shaft bone, the leading portion having first and second sections. The apparatus further includes an expansion mechanism adapted to transition the first and second sections from a first position to a second position, the first and second sections providing an outward force against the inside surface of the cortical shaft bone when the first and second sections transition from the first position to the second position, the trailing portion of the housing abutting a leading end of the affected cortical shaft bone. The trailing portion of the housing includes a pair of angled tapers extending inwardly toward each other to a minimum separation distance at an extreme end of the housing.
US11523848B2	Paraxial revision rod-to-rod connector Disclosed herein are an orthopedic rod-to-rod connector and rod-to-rod connector assemblies for spinal fusion surgery. The rod-to-rod connector may include a first connector portion and a second connector portion. The first connector portion may have a first aperture configured to receive at least a portion of a bone-engaging screw and a first spinal rod. The second connector portion may be rotatably connected with the first connector portion and may include a second aperture to receive a second spinal rod. The second connector portion may be L-shaped and may include a set screw to control rotation of the first connector portion with respect to the second connector portion.
US11523847B2	Fasteners with interlocking gripping threads for bone anchor receivers A receiver assembly for securing an elongate rod to a bone anchor includes a receiver having pair of upright arms that define an open channel configured to receive the elongate rod, a discontinuous helically wound receiver guide and advancement structure formed into the interior surfaces of the upright arms, and horizontally-elongated tool engaging grooves formed into upper portions of the outer surface of the upright arms. The receiver assembly further includes a closure configured for positioning within the open channel to secure the elongate rod to the receiver in a locked configuration, with the closure having an outer surface with a mating continuous helically wound closure guide and advancement structure configured to resist a tendency toward splaying between the upright arms upon a screwing in of the closure within the open channel by rotatable engagement with the receiver guide and advancement structure.
US11523829B2	Vaso-occlusive devices with in-situ stiffening A vaso-occlusive device is constructed out of dissimilar metallic materials that are in contact or otherwise in close proximity with one another, thereby causing the device to undergo galvanic corrosion when exposed to an electrolytic medium, such as blood or other body fluid, wherein one of the dissimilar metallic materials is zirconium or zirconium alloy to create a corrosive product including zirconia having a relatively high hardness, a relatively high fracture toughness, and a relatively high stability when the device is implanted in a vasculature site, such as an aneurysm.
US11523828B2	Sealed reload assembly for stapling device A stapling device includes a handle assembly, an adaptor assembly extending from the handle assembly, and a reload assembly supported on a distal end portion of the adaptor assembly. The reload assembly includes a shell housing, a staple cartridge, a first seal, a staple actuator, and a knife carrier. The first seal is disposed within a cavity of the shell housing and defines a staple actuator opening and a knife carrier opening. The staple actuator includes a proximal leg extending proximally therefrom and through the staple actuator opening of the first seal to provide a fluid seal therebetween. The knife carrier includes a proximal body portion extending proximally therefrom and through the knife carrier opening of the first seal to provide a fluid seal therebetween.
US11523822B2	Battery pack including a circuit interrupter A battery pack for use with a surgical instrument is disclosed. The battery pack comprises a battery housing, batteries positioned in the battery housing, and an interruption member. The battery housing includes electrical contacts configured to electrically couple the battery pack to the surgical instrument when the battery pack is attached to the surgical instrument. The interruption member is movable from a first position where the interruption member electrically disconnects at least one battery from another battery and a second position. The batteries are electrically connected to the surgical instrument when the interruption member is moved from the first position to the second position and the battery pack is attached to the surgical instrument.
US11523819B2	Suturing thread for facelift and body lift The present invention relates to a suturing thread for providing a more efficient lift procedure, and provides a suturing thread for a facelift and a body lift, wherein the suturing thread is made of a polymer material and has a plurality of conical protrusions or a plurality of funneled protrusions formed on an outer circumferential surface of a main thread of the suturing thread.
US11523818B2	Suture passer devices and methods Suture passer devices and methods of using the devices having one or more protective interlocks preventing or limiting operation of the suture passer when deployment of the needle may damage the apparatus or harm the patient. For example, described herein are suture passer devices that include an interlock preventing deployment of the tissue penetrator (needle) when the jaws are not clamped onto a tissue. Also described herein are interlocks preventing retraction of a jaw axially until the needle is retracted.
US11523817B2	Endoluminal pursestring device An endoluminal pursestring device is provided and includes a handle assembly, a shaft, an elongated fork, a plurality of surgical fasteners disposed with the shaft, and a suture engaged with the surgical fasteners. The suture is secured to a head of each of the surgical fasteners, and extends proximally through the handle assembly. In use, a distal end of the endoluminal pursestring device is positioned adjacent tissue surrounding a lumen, and the handle assembly is rotated to cause the distal-most surgical fastener to be rotated into the tissue. The following surgical fasteners are also rotated into other portions of the tissue surrounding a lumen. The suture connecting each of the surgical fasteners is then pulled such that the surgical fasteners are pulled together, thereby closing the lumen.
US11523815B2	Side-loading knot cutter A knot pushing and suture-cutting device is disclosed including a handle having a multi-positional control and an inner shaft and outer tube extending from the handle. The inner shaft and outer tube both comprise slots and the outer tube is both axially and rotationally moveable relative to the inner shaft, to move the inner shaft and outer tube slots relative to each other. In a first configuration, the inner shaft and outer tube slots are aligned and configured to receive a suture therein. In a second configuration, the slots are configured to lock the suture within a lumen of the inner shaft. In a third configuration a cutting edge on the outer slot is configured to cut the suture.
US11523813B1	Soft button assembly and procedure A suture construct having a soft button, defining a multiplicity of first apertures and a set of second apertures. Also, a suture loop assembly has a suture defining a lumen and forming a double loop, formed by a double trap having a first end and a second end, formed in a trap region of the suture, and in which a first portion of the suture is threaded through the trap region lumen from the first end to the second end and the first portion extends out from the second end, and a second portion of the suture is threaded through the trap region lumen from the second end to the first end, and the second portion extends out from the first end. Finally, the double loop passes through the set of second apertures of the soft button.
US11523810B2	Percutaneous compression and distraction system The present invention provides a compression and distraction shaft assembly used to apply compression and distraction to bones including vertebrae. Shaft A assembly and shaft B assembly are attached together via a polyaxial fulcrum. The polyaxial fulcrum allows all rotational degrees of freedom between shaft A assembly and shaft B assembly. Such fulcrum, during compression and distraction, does not impart ancillary stresses or motion to vertebrae. An hourglass-shaped bore for engaging pliers is formed in approximately middle of both the shaft A assembly and the shaft B assembly. Distraction pliers having cylindrical tips are used to apply distraction to vertebrae. Once handles are pressed to impart an appropriate amount of distraction to the vertebrae, they are locked in this position. Compression pliers having cylindrical tips are used to apply compression to vertebrae. Once handles are pressed to impart an appropriate amount of compression to the vertebrae, they are locked in this position.
US11523809B2	Independent rod suspension In one embodiment, an assembly includes a retractor (30, 730, 930) and at least one cylindrical rod (102, 402, 502, 702, 802, 902) attached to the retractor. The rod has a fixed length portion (108, 406, 508, 708, 808, 908) and a spring portion (104, 404, 504, 718, 832, 905). The spring portion of the rod has a longitudinal dimension that changes as a function of loading on the rod. When the rod is in contact with a solid surface such as a bone, it maintains contact with such surface even while changing shape due to loading on the rod. When the assembly includes multiple rods attached to the retractor, both spring-based rods and other types of rods may be used in combination.
US11523806B2	Impact biopsy device and method of use An impact biopsy device is disclosed. The impact biopsy device may be configured to displace various cutting elements, such as an outer tubular member and cutting element and a cannula to sever a tissue sample from a patient. The impact biopsy device may comprise an actuation system configured to transfer displacement or force to the cutting elements by the impact of an element on another element.
US11523804B2	Ultrasonic diagnosis device and temperature management method In order to estimate a temperature of a transmission-reception wavefront of a probe head, a first computing unit and a second computing unit are provided. The first computing unit estimates a temperature TA of the transmission-reception wavefront according to a basic function based on an internal temperature T1, an ambient temperature T2, power consumption Ptotal (=Pic+Ptd), and any other parameter. The basic function is a linear function. The second computing unit estimates a temperature TB of the transmission-reception wavefront according to an auxiliary function based on a previously estimated temperature Tpre, an internal temperature difference ΔT1, and any other, parameter. A selection unit selects any of the temperatures TA and TB depending on situations.
US11523801B2	Automatically identifying anatomical structures in medical images in a manner that is sensitive to the particular view in which each image is captured A facility for processing a medical imaging image is described. The facility applies to the image a first machine learning model trained to recognize a view to which an image corresponds, and a second machine learning model trained to identify any of a set of anatomical features visualized in an image. The facility accesses a list of permitted anatomical features for images corresponding to the recognized view, and filters the identified anatomical features to exclude any not on the accessed list. The facility causes the accessed image to be displayed, overlaid with a visual indication of each of the filtered identified anatomical features.
US11523799B2	Fetal imaging system and method An ultrasound fetal imaging system uses an acceleration sensor (16) for generating an acceleration signal relating to movement of the ultrasound transducer (10). A user is guided in how or where to move the ultrasound transducer based on the results of image processing of the ultrasound images. The user can thus be guided to move the transducer in a certain direction so as to achieve a complete scan of a fetus in a shortest possible time. This limits exposure of the expectant mother to the ultrasound energy. The fetal image obtained may be used to determine a fetal weight, for example using regression analysis based on some of the parameters derived from the obtained image.
US11523797B2	Vital sign detection and measurement An example monitoring device for detecting and measuring a vital sign of a subject includes: a base; a battery mounted to the base; first and second transceivers attached to the base at opposing angles, and powered by the battery to transmit pulses and receive reflected pulses; an antenna powered by the battery, and configured to wirelessly transmit data acquired from the first and second transceivers; and a computing device powered by the battery, and operatively coupled to the first and second transceivers and the antenna, the computing device having a processing device and a memory storing instructions that, when executed by the processing device, cause the monitoring device to determine a respiration rate by detecting a cyclical change in distance based on the reflected pulses.
US11523790B2	Systems, methods, computing devices, and storage media for medical examination The present disclosure relates to systems, methods, computing devices, and storage media for medical examination. The medical examination system comprises: a breathing guiding apparatus configured to guide a breathing of a subject; an imaging device configured to scan the subject; and a controller coupled to the breathing guiding apparatus and configured to cause the breathing guiding apparatus to generate a breath guiding state for guiding the breathing of the subject.
US11523788B2	Medical information processing apparatus, medical information processing system, and medical information processing method A medical information processing apparatus includes processing circuitry. The processing circuitry is configured to acquire medical image data representing a blood vessel of a subject, extract a blood vessel shape from the medical image data, determine degree of meandering in each of regions from the extracted blood vessel shape, specify a deformed region in which the degree of meandering changes due to insertion of a device into the blood vessel on the basis of the degree of meandering, and output the deformed region in the blood vessel.
US11523785B2	Increased cone beam computed tomography volume length without requiring stitching or longitudinal C-arm movement A medical imaging system includes a movable station having a C-arm, a collector, an X-ray beam emitter, and a controller. The collector is attached to a first end of the C-arm. The X-ray beam emitter faces the collector to emit an X-ray beam in a direction of the collector and is attached to a second end of the C-arm. The controller moves one of the X-ray beam emitter and the collector to a first offset position along a lateral axis orthogonal to the arc, and obtains a first set of images by rotating the collector and the X-ray beam emitter along the arc about a scanned volume. The controller moves the one of the X-ray beam emitter and the collector to a second offset position along the lateral axis, and obtains a second set of images. The controller combines the first and second set of images to generate a three-dimensional image of the scanned volume.
US11523784B2	Portable medical imaging system Medical imaging devices, systems, and methods thereof. The medical imaging system may include a movable station and a gantry. The movable station includes a gantry mount rotatably attached to the gantry. The gantry includes an outer C-arm slidably mounted to and operable to slide relative to the gantry mount, an inner C-arm slidably coupled to the outer C-arm and, an imaging signal transmitter and sensor attached to the C-arms. The two C-arms work together to provide a full 360 degree rotation of the imaging signal transmitter. In embodiment, the imaging signal transmitter and imaging sensor are offset from a center axis of the medical imaging system such that the portable medical imaging system is operable to capture an enlarged field of view.
US11523781B2	Method for running a collision protection system for a medical operating device, medical operating device, computer program, and data storage medium A method is provided for running a collision protection system for a medical operating device, which has a patient bed for a patient to be operated on, an image recording device having at least one movable image recording component for recording image data of the patient during the operation, and an assistance robot having a movable assistance component which during the operation is situated at least temporarily inside the patient and/or is coupled in terms of movement to an instrument situated inside the patient. In the method, an item of criticality information is determined which describes the criticality of possible collisions of components of the operating device and/or movements of the patient with regard to the interaction of the assistance robot with the patient. Depending upon the criticality information, when a criticality criterion indicating a raised criticality, (e.g., a criticality exceeding a threshold value), is met, a safe mode of operation of the collision protection system is activated, which meets higher safety requirements than a normal mode of operation.
US11523778B2	Systems and methods for detecting worsening heart failure Systems and methods for detecting worsening cardiac conditions such as worsening heart failure events are described. A system may include sensor circuits to sense physiological signals and signal processors to generate from the physiological signals first and second signal metrics. The system may include a risk stratifier circuit to produce a cardiac risk indication. The system may use at least the first signal metric to generate a primary detection indication, and use at least the second signal metric and the risk indication to generate a secondary detection indication. The risk indication may be used to modulate the second signal metric. A detector circuit may detect the worsening cardiac event using the primary and secondary detection indications.
US11523773B2	Biofeedback for therapy in virtual and augmented reality Adjustment of training protocols in virtual reality (VR) or augmented reality (AR) environments based on biofeedback are provided. In various embodiments, motion data is collected for a user while the user performs a training protocol in a virtual environment. A biometric measurement is collected for the user while the user performs the training protocol. The motion data and the biometric measurement are provided to a learning system at a remote server. The learning system determines an adjustment to the training protocol based on the motion data and the biometric measurement. The adjustment is provided by the learning system and is applied to the training protocol. In various embodiments, the adjustment, the motion data, and/or the biometric measurement may be logged in an electronic health record.
US11523770B2	Systems and methods for itch monitoring and measurement A system for monitoring and measuring itch of a patient includes a wearable device including an actigraph sensor; and a controller electrically connected to the wearable device and including a processor and a memory. The wearable device is configured to measure, via the actigraph sensor, a movement of the patient; and send data indicative of the measured movement of the patient to the controller. The controller is configured to receive, via the processor, the data indicative of the measured movement; and determine, via the processor, a scratching movement of the patient based on the data indicative of the measured movement.
US11523764B2	Methods and systems for measuring brain activity The invention encompasses systems and methods allowing for minimally invasive insertion and functional optimization of implantable electrode arrays designed for placement within the subgaleal space to record brain electrical activity. The implantable arrays comprise a support structure capable of being implanted in the subgaleal space and comprising at least one reference element; at least one ground element; and one or more recording elements; and wherein said array is capable of detecting and/or transmitting a subgaleal electrical signal.
US11523763B2	Implantable electrode device and a method for manufacturing thereof An implantable electrode device includes a carrier made of a polymer material, at least one measurement electrode formed by an electrically conducting pad located on the carrier, wherein the electrically conducting pad has a contact surface, a barrier layer enclosing the carrier by covering all surfaces of the carrier, wherein the contact surface of the electrically conducting pad is exposed to an outside environment, at least one electrically conducting trace, and at least one electrically conducting terminal. The electrically conducting trace can electrically connect the measurement electrode to the electrically conducting terminal. A surface of the implantable electrode device on a side on which the measurement electrode is located can have a maximum valley depth or a maximum peak height between the contact surface of the measurement electrode and a meanline of a surface of the implantable electrode device, excluding measurement electrodes, being equal to or smaller than 100 micrometres.
US11523761B2	Method and system for assessment of cognitive workload using breathing pattern of a person This disclosure relates generally to assessment of cognitive workload using breathing pattern of a person, where cognitive workload is the amount of mental effort required while doing a task. The method and system provides assessment of cognitive workload based on breathing pattern extracted from photoplethysmograph (PPG) signal, which is collected from the person using a wearable device. The PPG signal collected using the wearable device are processed in multiple stages that include breathing signal extraction to extract breathing pattern. The extracted breathing pattern is used for assessment of cognitive workload using a generated personalized training model, wherein the personalized training model is generated and dynamically updated for each person based on selection of a sub-set of breathing pattern features using feature selection and classification techniques that include maximal information coefficient (MIC) techniques. Finally based on personalized training model, the extracted breathing pattern is classified as high cognitive workload or low cognitive workload.
US11523759B1	System and method for biometric monitoring and educational analysis optimization using artificial intelligence Systems and methods for educational analysis optimization. The system includes a camera, a processor and memory. The memory stores instructions to execute a method. The method begins with receiving a request from a user at a client device to begin a stimulus session. Then, video recording of the user for the stimulus session is initialized. Next, calibrations for emotions and gaze are set. Then, one or more stimuli are presented to the user. Cues and reactions are recorded and mapped to content that was displayed during the times of recorded reactions and cues. The recordings are post-processed for educational analysis and feedback is provided to the user. The feedback and analysis can be optimized using a predictive artificial intelligence model.
US11523758B2	SpO2 sensor having partitioned electronics A sensing device for acquiring data from a finger. The device includes a carrier board having a stacked portion with a finger side and a canopy side. A tip wing extends from the stacked portion and wraps around the finger. Electrical components are coupled to the carrier board, including a first circuit board on the canopy side of the stacked portion, and one or more optical components electrically on the tip wing. The optical components are configured to transmit light towards the finger and to detect the light from the finger. The carrier board electrically couples the electrical components to acquire the data from the finger. A power system is positioned between the canopy side and the finger side of the carrier board, where the power system provides power to the electrical components via the carrier board. A cover secures the carrier board to the finger.
US11523756B1	Detecting middle ear abnormalities using a smartphone-based tympanometer A smartphone and tympanometer-based middle ear abnormality detection mobile system and a method for detecting middle ear abnormalities by a mobile computing device coupled to a tympanometer is disclosed. The method detects middle ear abnormalities by a smartphone-based tympanometer, thereby allowing mobility for medical practitioners to check for middle ear abnormalities in people unable to visit an ENT at a medical facility. The method is implemented as a software application that runs on the mobile computing device and displays results instantly to help determine any of several types of middle ear infection which may be present. This is a huge improvement over existing process where a doctor has to make that determination based on his/her interpretation of the tympanogram.
US11523755B2	Device and method for detecting and compensating for an oblique ear probe insertion The present disclosure relates to a device and method for detection and compensation for an oblique ear-probe insertion in especially hearing testing diagnostic setups. More particularly the disclosure relates to detecting an oblique probe insertion from an ear-probe measurement and estimated characteristic impedances and compensate for its effect on the ear-canal reflectance.
US11523754B2	Device and relative method for determining extrapyramidal symptoms, in particular motor symptoms of Parkinson's disease A method and a related device to determine the kinetic state of a subject includes the steps of determining a signal indicative of the acceleration trend on the three Cartesian axes; processing the signal to limit the frequency band and preferably reduce artifacts and compensate the offset of the output signals from a multi-axial measurement system; analyzing frequency and spectrum through the transformation of the signal with the Fournier transform; computing the power spectral density for each Cartesian axis; and comparing the spectral density with a characteristic pattern of a movement.
US11523752B2	Assay for vapor condensates The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).
US11523751B2	Breath analyzer, system, and computer program for authenticating, preserving, and presenting breath analysis data A breath analyzer, a system, and a computer program for administering a breath analysis to a donor and recording a breath analysis result. Embodiments of the invention authenticate that the breath analysis was performed correctly, preserves the breath analysis results by communicating with other devices, and presents the breath analysis results by superimposing them on recorded video data. The breath analyzer includes a breath receptor for receiving a breath sample from the donor, an analyzing element for determining a breath analysis result, a communications element for sending information indicative of the breath analysis result to a recording device manager, and a housing for securing the components in a handheld device. The system comprises the breath analyzer, a recording device manager for synchronizing the recordings, and at least one ancillary camera for recording the breath analysis.
US11523748B2	Catheter with single axial sensors A catheter has single axis sensors mounted directly along a portion of the catheter whose position/location is of interest. The magnetic based, single axis sensors are on a linear or nonlinear single axis sensor (SAS) assembly. The catheter includes a catheter body and a distal 2D or 3D configuration provided by a support member on which at least one, if not at least three single axis sensors, are mounted serially along a length of the support member. The magnetic-based sensor assembly may include at least one coil member wrapped on the support member, wherein the coil member is connected via a joint region to a respective cable member adapted to transmit a signal providing location information from the coil member to a mapping and localization system. The joint region provides strain relief adaptations to the at least one coil member and the respective cable member from detaching.
US11523742B2	System, method, and apparatus for temperature asymmetry measurement of body parts Systems, methods, and apparatus for identifying a health disorder based on a temperature asymmetry estimation. A system may include a thermal camera configured to detect thermal images of an inspected body part and a reference body part, which may be contralateral to the inspected body part. The system may further include an optical camera configured to detect optical images of the inspected body part and the reference body part. The system may further include a remote mobile device having a mobile processor programmed to control the thermal camera to detect the thermal images and the optical camera to detect the optical images. The system may further include remote server having a diagnostic processor programmed to determine that a functional disorder or inflammation of the inspected body part has occurred by analyzing the thermal images and the optical images.
US11523739B2	Multispectral detection and presentation of an object's characteristics An apparatus for capturing a multispectral image of an object is described. The apparatus includes one or more means for transmitting a beam of laser light at a first wavelength and a beam of laser light at one or more additional wavelengths different from the first wavelength. There is a means for causing the beams of laser light to travel in a coaxial path and a moving mirror. The beams of light bounce off the mirror thereby producing a two dimensional projection pattern. This pattern travels from the mirror along a first path to an object and wherein some of the laser light penetrates the object and travels to an internal structure of the object. The reflection of the laser light returns to a photo detector along a path different from said first path.
US11523735B2	Flexible headrest for ophthalmic instrument A headrest for an ophthalmic instrument facilitates fine positioning of the instrument relative to an eye of a test subject without the need to remove a contact element of the headrest from contact with the test subject's face. The ophthalmic instrument may be, for example, a rebound tonometer or a non-contact tonometer. The headrest includes a hollow bulbous contact element formed of resiliently deformable material, for example a thermoplastic elastomer (TPE) or silicone rubber. An outer surface of the contact element may have a spherical shape or a spheroidal shape when the contact element is not deformed.
US11523731B2	Laryngoscope with blade locking mechanism A laryngoscope assembly having a handle for connection with a laryngoscope blade and wherein the handle includes an additional mechanism for securing the blade to the handle. A locking mechanism is a spring provided for holding the blade in position on the handle and preventing side to side movement of the blade with respect to the handle.
US11523729B2	Surgical controlling device, control method, and surgical system There is provided a surgical controlling device including an exposure controlling section that performs exposure control based on a luminance detection value detected from a biological image, in which the exposure controlling section corrects, on the basis of information regarding an identified surgical optical device, the luminance detection value so as to correct luminance unevenness arising from the surgical optical device. Further, there is provided a control method including performing, by a processor, exposure control based on a luminance detection value detected from a biological image, in which the performing the exposure control further includes correcting the luminance detection value so as to correct, based on information regarding an identified surgical optical device, luminance unevenness arising from the surgical optical device.
US11523725B2	Portable extractor A portable cleaner has a recovery tank, including a container for receiving and storing recovered liquid and/or dirt and an openable tank lid for covering the container. The container and the tank lid are removable from the cleaner as a unit. The portable cleaner also has a main housing configured to removably support the recovery tank in a vertical orientation in which the tank lid at least partially defines a top side of the portable extraction cleaner. In addition, a tank latch is provided in the tank lid, the tank latch configured to selectively secure and release the tank lid to the main housing when the recovery tank is supported by the main housing.
US11523723B2	Polishing machine A floor polishing machine for concrete includes a frame with an integrated hydraulic fluid tank, a hydraulic drive system, and a hydraulic pump vacuum system. Further, the machine provides a swivel polishing head that provides abutting contact with a floor and includes a floating ring and rubber skirts that seals the polishing head. The machine provides interchangeable wet and dry vacuum systems for collection of the slurry during wet operation and dust during dry operation. A support member inserts into a receiving sleeve for a choice of wet or dry option. A squeegee system attached to the rear of the apparatus collects slurry and operates to send the slurry to a collection tank. The squeegee lifts out of the way during dry operation.
US11523722B2	Dirtiness level determining method and electronic device applying the dirtiness level determining method A dirtiness level determining method applied to an electronic device comprising an image sensor. The method comprises: (a) capturing a first image at a first time point according to first type of light; (b) capturing a second image at a second time point after the first time point according to the first type of light; (c) calculating a first fixed pattern according to a first difference between the first image and the second image; and (d) calculating a first dirtiness level of the image sensor according to the first fixed pattern; (e) generating a first notifying message if the first dirtiness level is higher than a dirtiness threshold.
US11523721B2	Vacuum cleaner A vacuum cleaner including: a suctioning unit; a main body including a cyclone part for separating dust from suctioned air and a dust container for storing the separated dust, and a body cover for opening and closing the lower side of the body; a filter unit, disposed in the body, for filtering air separated from the dust; an actuating unit capable of moving in the body between the outside of the filter unit and the inner circumference surface of the body; an operating unit disposed outside the body which operates in order to move the actuating unit; a transmission unit penetrating the body and connecting the actuating unit with the operating unit; and an elastic member disposed outside the body which elastically supports the operating unit.
US11523718B2	Toilet brush with quick replaceable cleaning head A toilet brush with a quick replaceable cleaning head is disclosed herein. It comprises a rod body having a first end and a second end; a handle disposed at the first end of the rod body; a feeding unit for connecting the handle; an action rod accommodated in the rod body for connecting the feeding unit and having a clamping head; and a cleaning head having a sleeve and an aperture into which the clamping head is inserted.
US11523717B2	Air dispensing chamber An air dispensing chamber, including a main body, a plurality of fans circumferentially disposed within at least a portion of the main body to blow air toward a center of the main body in response to rotation of the plurality of fans, and a drainage unit disposed within at least a portion of the main body to receive a liquid therein.
US11523710B2	Coffee containers and associated system and method for preparing roast and ground coffee A coffee bean container configured to store green and/or partially roasted coffee beans includes an inner volume where the beans are stored, roasting means allowing beans to roast at a certain required degree depending on the original roasting level of the stored beans, and at least part of a grinder to allow for grinding of the beans, once roasted, to a certain grinding size. The roasting means may be a roasting hollow tube through which pressurized hot air circulates such that coffee beans circulate inside the tube and within the internal volume, creating a fountain effect.
US11523705B2	Water ejecting apparatus A water ejecting apparatus includes a case and a water ejection unit connected to one side of the case. The water ejection unit includes a fixed cover, a lifting cover, a lifting motor, a water ejection nozzle, a touch bar, a detection sensor, and a controller. The fixed cover is connected to the case. The lifting cover is movably received in the fixed cover and coupled to the lifting motor. The water ejection nozzle is installed at a lower end of the lifting cover and configured to eject water. The touch bar is at least partially received in the lifting cover and moves when in contact with a container placed below the water ejection nozzle. The detection sensor detects movement of the touch bar. The controller changes operation of the lifting motor when the detection sensor detects movement of the touch bar.
US11523703B2	Brewer system, method and apparatus A brewer system includes a reservoir, a steep chamber movable relative to the reservoir and positioned over a mouth of the reservoir, and a filter tape positioned between the chamber and the reservoir. Brewing substance and water are added to the chamber to form a brewed beverage that passes through the filter tape and into the reservoir through the mouth.
US11523700B2	Telescopic hanging rod for curtain fabric A telescopic hanging rod for a curtain fabric is disclosed, which comprises a hanging rod body and a telescopic mechanism arranged on at least one end of the hanging rod body; the telescopic mechanism comprises a first telescopic connecting portion connected to the hanging rod body, and a second telescopic connecting portion slidably connected with the first telescopic connecting portion; the first telescopic connecting portion and the second telescopic connecting portion are coaxially arranged. The length of the hanging rod can be adjusted to a certain degree in accordance with the size of the mounting space during the mounting process, thereby lowering difficulty in dimension measurement prior to installation. Besides, the width of a curtain fabric is also adjustable, hence, standard batched production is achieved, while the production scale is enlarged, and the production cost reduced.
US11523695B2	Sticky napkin and towel roll A sticky napkin is disclosed. The sticky napkin includes a first surface and an opposing second surface, a first fold line extending from the first side to the second side, a second fold line extending from the first side to the second side, a first adhesive strip overlaying the second surface of the first end section panel and extending in a direction from the first side to the second side, and a second adhesive strip overlaying the second surface of the second end section panel and extending in a direction from the first side to the second side.
US11523694B2	Adjustable pillow An adjustable orthopedic pillow includes a plurality of sections separated by dividers. Each section includes a head support fill chamber, a comfort layer fill chamber, a primary cervical support fill chamber, and a secondary cervical support fill chamber. The primary cervical support fill chamber can be positioned between at least a portion of the head support fill chamber and at least a portion of the comfort layer fill chamber and can an opening at a superior portion of the primary cervical support fill chamber. The secondary cervical support fill chamber can be positioned between at least a portion of the head support fill chamber and at least a portion of primary cervical support fill chamber and can include an opening at an inferior portion of the secondary cervical support fill chamber.
US11523692B2	Wall mounts for play yards An example play yard can include: a plurality of side panels configured to be coupled to one another to form the play yard, with each of the plurality of side panels being plastic; a yard mount configured to be coupled to a free end of one of the plurality of side panels, the yard mount including a first side configured to be coupled to the free end and a second side including a plurality of tabs with each forming an aperture therein; and a wall mount configured to be coupled to a structure, the wall mount including a plurality of members. As the yard mount is moved relative to the wall mount, each one of the plurality of members of the wall mount is received in the aperture of each respective tab of the plurality of tabs of the yard mount to couple the yard mount to the wall mount.
US11523684B1	Holder for consumer electronic device A holder includes first and second support surfaces, first and second bases, pivotal first and second legs, and a folding linking assembly. Front ends of the first and second support surfaces are pivotably secured to front ends of the first and second base respectively; each of the first and second support surfaces include a transverse groove in a central portion, a recess below a bottom, a lengthwise trough in a rear portion of a top, and a limit member moveably disposed in the first trough; each of the first and second bases include parallel first slits on a rear portion of a top; each of the first and second legs have an upper end pivotably secured to the bottom of the first or second support surface; and the folding linking assembly is pivotably disposed between the front ends of the first and second support surfaces.
US11523683B2	Blow-molded unitary structure with enhanced strength A blow-molded unitary structure includes a panel having upper and lower panel surfaces and a ridge extending downward beyond the lower panel surface. The ridge includes a first side surface, a second side surface, and a lower ridge surface joined with the first side and second side surfaces of the ridge. The ridge further includes a plurality of depressions formed at one or more of the first side surface, second side surface and lower ridge surface. The plurality of depressions enhances the strength of the ridge, and the ridge in turn enhances the strength of the structure.
US11523681B2	Frame and table having structure for reducing vibration A table includes a table panel, first and second mounting members, and first and second leg assemblies. Each of the first and second mounting members is coupled or formed with the table panel. Each of the first and second leg assemblies includes a linking member having an end portion rotatably coupled with the first mounting member and another end portion rotatably coupled with the second mounting member. When the first or second leg assembly is unfolded, the linking member abuts one or more retainers of the table panel and forms interference fit with the first and second mounting members. This significantly reduces vibration when the table is in use.
US11523680B2	Slicker brush having halo-illuminated light The present invention offers a halo-illuminating light pattern for clearly showing areas of a pet's fur to the user performing brushing. Such a halo-illuminating light pattern provides a full, 360-degree light pattern of the pet's fur. This eliminates the necessity for using an additional light source, for example a flashlight or being made to settle on a light source that only highlights one side of a pet's fur, leaving another side in shadow.
US11523678B2	Oral care system including an oral care implement and a tracking attachment, tracking attachment thereof, and method of assembling the same An oral care system that includes an oral care implement and a tracking attachment. The oral care implement may include a handle and a head. The tracking attachment is detachably coupled to the oral care implement. The tracking attachment may include a housing including a first housing portion having an inner surface that defines a first cavity and a second housing portion having an inner surface that defines a second cavity. The tracking attachment may also include a tracking unit configured to facilitate tracking at least one of a position, orientation, or movement of the oral care implement to which it is attached. A first portion of the handle may be positioned within the first cavity and a second portion of the handle may be positioned within the second cavity.
US11523674B2	Support system for electronic device Systems and apparatuses for supporting electronic devices are described. Such systems and apparatuses provide significant adaptability to position an electronic device in commonly used locations by using an interface that is readily provided in virtually any location. Furthermore, the systems and apparatuses described herein include cradles that adaptable to a wide array of electronic device dimensions, including width and depth or thickness.

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