Document Document Title
US11326086B2 Drilling fluid for downhole electrocrushing drilling
An electrocrushing drilling system containing an electrocrushing drill bit with electrodes through which a voltage may be discharged that are at least 0.4 inches apart at their closest spacing and an electrocrushing drilling fluid including a polar oil, a non-polar oil, or a combination thereof and water are described. Methods of electrocrushing drilling using such a system are also described.
US11326084B2 Cold storage material composition and use thereof
A cold storage material composition is provided allowing for temperature maintenance of a temperature control target article in various control temperature ranges in a range of −75° C. to −55° C. and being capable of solidifying within a given period of time and (ii) a technique of using the cold storage material composition. Also provided is a cold storage material composition including calcium ions, chloride ions, bromide ions, and ammonium ions in respectively specific amounts, relative to 100 mol of water, and having a melting temperature in a range of −75° C. to −55° C.
US11326080B2 Self-stick insulation and methods
A method of using a self-stick insulation. The method includes providing a piece of insulation product with an adhesive coating. The adhesive coating includes polystyrene-maleic anhydride (SMA) and/or polyacrylic acid (PAA); an alcohol amine; and at least one of a polyvinyl alcohol and a starch. The adhesive coating is then activated with liquid water. Once the adhesive coating is active, the insulation product is attached to a surface with the adhesive coating.
US11326078B2 Solvent composition, adhesive composition, and method of bonding surfaces
In an embodiment a solvent composition can comprise, based on the total volume of the solvent composition, 10 to 95 volume percent of a first solvent, wherein the first solvent has Hansen solubility parameters of: 15 MPa0.5≤δD≤17 MPa0.5, 4≤δP≤10.5 MPa0.5, and 7≤δH≤10 MPa0.5; 5 to 95 volume percent of a second solvent, wherein the second solvent has Hansen solubility parameters of: 16 MPa0.5≤δD≤17.5 MPa0.5, 0≤δP≤3 MPa0.5, and 0≤δH≤3 MPa0.5; and 0 to 85 volume percent parachlorobenzotrifluoride; wherein the amounts of the first solvent, the second solvent, and parachlorobenzotrifluoride sum to at least 85 volume percent. The first solvent can comprise methyl acetate, acetone, dimethyl carbonate, ethyl acetate, n-butylamine, propyl acetate, tetrahydrofuran, or a combination thereof. The second solvent can comprise cyclohexene, cyclohexane, cyclopentane, methylcyclohexane, or a combination thereof. The solvent compositions are particularly useful in an adhesive composition. An adhesive composition includes the solvent composition, a rubber, and a tackifying resin. A method of bonding two surfaces is also described.
US11326074B2 Slurry floor treatment technology, such as curable epoxy resin-based systems, other resin systems, and related resin coat methods
The invention provides a method of treating a floor, such as with a curable epoxy resin-based system or another resin system. The method involves mixing together a Part A comprising a resin and a Part B comprising a hardener to form an activated multicomponent resin system. In certain embodiments, the activated multicomponent resin system has a viscosity in a range of 900-1,200 centipoise. The method further comprises mixing a Part C comprising particles into the activated multicomponent resin system to form a slurry, spreading the slurry over a floor to form a slurry coat, and allowing the slurry coat to cure. Before and after the slurry coat has cured, it has particles of the Part C distributed substantially uniformly throughout. The invention also provides slurry floor coats and floors bearing such coats, as well as methods for repairing such floor coats and floors.
US11326069B2 Fluorine-containing active energy ray curable resin, surfactant, active energy ray curable resin composition, and cured film
Objects are to provide a fluorine-containing active energy ray curable resin which may be suitably used as a surfactant in an aqueous active energy ray curable resin composition, to provide an active energy ray curable resin composition including the resin, and to provide a cured product obtained by curing the composition. Specifically, a fluorine-containing active energy ray curable resin is provided which includes a polymer structure (a1) derived from a radically polymerizable unsaturated monomer, a poly(perfluoroalkylene ether) chain (a2), a radically polymerizable unsaturated group (a3), and an acid group forming a neutral salt structure (a4). Also provided are a surfactant including the fluorine-containing active energy ray curable resin; an active energy ray curable resin composition including the fluorine-containing active energy ray curable resin, an active energy ray curable hydrophilic resin other than the fluorine-containing active energy ray curable resin, and water; and a cured film of the composition.
US11326065B2 Silicone resin reflective substrate, manufacturing method for same, and base material composition used in reflective substrate
A versatile silicone resin reflective substrate which exhibits high reflectance of high luminance light from an LED light source over a wide wavelength from short wavelengths of approximately 340-500 nm, which include wavelengths from 380-400 nm near lower limit of the visible region, to longer wavelength in the infra-red region. The silicone resin reflective substrate has a reflective layer which contains a white inorganic filler powder dispersed in a three-dimensional cross linked silicone resin, the inorganic filler powder having a high reflective index than the silicone resin. The reflective layer is formed on a support body as a film, a solid, or a sheet. The silicone resin reflective substrate can be easily formed as a wiring substrate, a packaging case or the like, and can be manufactured at low cost and a high rate of production.
US11326063B2 Fibrous carbon nanostructure dispersion liquid
Provided is a fibrous carbon nanostructure dispersion liquid having excellent fibrous carbon nanostructure dispersibility. The fibrous carbon nanostructure dispersion liquid contains a solvent and one or more fibrous carbon nanostructures having a percentage mass loss of 3.0 mass % or less upon heating from 23° C. to 200° C. at a heating rate of 20° C./min in a nitrogen atmosphere as measured by thermogravimetric analysis.
US11326062B2 Colorless copper-containing material
Aspects of this disclosure pertain to a colorless material that includes a carrier, copper-containing particles, and either one or both of sodium thiocyanate and titanium dioxide. In one or more embodiments, the material exhibits, in the CIE L*a*b* system, an L* value in the range from about 91 to about 100, and a C* value of less than about 7, wherein C* equals √(a*2+b*2). In some embodiments, the material exhibits a greater than 3 log reduction in a concentration of Staphylococcus aureus, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing conditions.
US11326061B2 High content polyamide hot-applied thermoplastic composition
A hot applied thermoplastic pavement composition and method of using a hot applied thermoplastic pavement composition includes a modified polyamide resin in the range of between 3 and 10 percent by weight, wherein the composition contains rosin-modified esters, a copolymer, 30-70 percent by weight of a glass bead intermix, a range of between 1 and 15 percent by weight of either white or yellow pigment, the balance of the composition being selected from the group consisting of one or more plasticizers, inorganic fillers, waxes, antioxidants and light stabilizers.
US11326060B2 Liquid-repellent coatings
The invention relates generally to liquid-repellent coatings, and in particular, to porous liquid-repellent coatings, a method of preparing the porous liquid-repellent coatings, and a method of characterizing a porous surface for the liquid-repellent coatings. The invention further relates to a porous liquid-repellent coating comprising a porous layer of a transition metal oxide and/or hydroxide and a layer of a liquid-repellent compound deposited onto the porous layer of the transition metal oxide and/or hydroxide, wherein the porous layer of the transition metal oxide and/or hydroxide is comprised of a plurality of surface pores of varying angles with an average angle that is re-entrant.
US11326057B2 Automatic sorting of polymer materials on the basis of the fluorescence decay time of the intrinsic fluorescence of the polymer
The invention relates to the identification of polymer materials on the basis of the fluorescence decay time of the intrinsic fluorescence of the polymer materials for definite sorting in a completely separated manner. The invention further relates to marking with fluorescent dyes, which, because of the specific fluorescence decay times of the fluorescent dyes, can further increase the sorting reliability by means of redundancy and can be used to identify particular batches.
US11326055B2 Aerogel composite powder
The present invention relates to an aerogel composite powder superior in thermal insulation and flexibility, the aerogel composite powder comprising an aerogel component and a silica particle.
US11326052B2 Biodegradable plastic composition and manufacturing method thereof
A biodegradable plastic composition is used to manufacture a biodegradable plastic. The biodegradable plastic composition includes a biodegradable polyester, a polysaccharide, and a modifier. The modifier is used to compound the polysaccharide and the biodegradable polyester to obtain a biodegradable plastic. The biodegradable plastic has a tensile strength greater than 3 MPa and an elongation greater than 81%.
US11326051B2 Method for producing oxymethylene polymer and oxymethylene polymer resin composition
It has been desired to develop a method for producing an oxymethylene polymer, by which an oxymethylene polymer having a high polymerization degree can be produced with high efficiency while suppressing increase in the amount of generation of an odor. Further, it has been desired to develop an oxymethylene polymer resin composition, wherein generation of an odor at the time of molding or after molded to obtain a molded body is suppressed. The present invention provides a method for producing an oxymethylene polymer, wherein the oxymethylene polymer is produced by polymerizing a cyclic oligomer of formaldehyde, and wherein a boron trifluoride compound and an aryl fluoride boron compound are used as polymerization catalysts. The present invention also provides an oxymethylene polymer resin composition containing an oxymethylene polymer and a derivative of an aryl fluoride boron compound.
US11326048B2 Member, container, chemical liquid storage body, chemical liquid purification device, and manufacturing tank
A member contains a fluorine-containing polymer and a fluorine-containing surfactant, in which provided that a mass-based content of the fluorine-containing surfactant in at least a surface of a portion of the member is M1, and a mass-based content of the surfactant in a position 10 nm below the surface in a thickness direction of the member is M2, M1/M2 is 0.50 to 0.90, and an atom number ratio X1 of the number of fluorine atoms contained in the surface to the number of carbon atoms contained in the surface is 0.50 to 3.0.
US11326043B2 Compositions for high reinforced sidewalls
This invention provides a composition comprising a natural rubber, a polybutadiene rubber and an ethylene/α-olefin copolymer and/or ethylene/α-olefin multiblock copolymer. The invention also provides for methods of making the composition, and articles prepared from the composition.
US11326040B2 Silicon-containing halogenated elastomers
Described herein is curable composition comprising a halogenated amorphous polymer having at least 25% halogen by weight; at least 0.5 phr of an acid acceptor; at least 0.01 phr of silicon-containing compound; and a dehydrohalogenation cure system. Upon curing, a silicon-containing superficial layer forms, which can provide increased durability, non-tackiness, and a matte finish to the cured elastomer.
US11326033B2 Method to optimize atomic layer deposition
The disclosure provides a method to optimize atomic layer deposition comprising the following steps: (A) providing a cellulose nanofiber; (B) acidifying the cellulose nanofiber by an acidifying treatment agent; (C) hydrophobing the acidified cellulose nanofiber by a hydrophobinghydrophobic treatment agent; (D) dissolving the acidified and hydrophobed cellulose nanofiber in a solvent to form a cellulose nanofiber solution; (E) coating the cellulose nanofiber solution on a silicone resin film; (F) heating the coated silicone resin film to form a cellulose nanofiber layer on a surface of the silicone resin film; and (G) forming an inorganic coating layer on the surface of the silicone resin film having the cellulose nanofiber layer by atomic layer deposition.
US11326031B2 Thermoplastic resin sheet, laminated sheet, and molded object
Disclosed herein are a thermoplastic resin sheet having excellent mechanical strength and excellent conformability during molding, a laminated sheet using such a thermoplastic resin sheet, and a molded body. The thermoplastic resin sheet includes a thermoplastic resin containing a polyolefin resin, a polyamide resin, and a compatibilizer, wherein the compatibilizer is a modified elastomer having a reactive group that reacts with the polyamide resin. The laminated sheet includes a base layer containing a polyolefin resin and the thermoplastic resin sheet bonded to one surface of the base layer. The molded body includes a base body containing a polyolefin resin and the thermoplastic resin sheet or the laminated sheet bonded to one surface of the base body.
US11326030B2 Colorless and transparent polyamide-imide film, and manufacturing method therefor
Disclosed herein are a polyamide-imide film which is transparent and exhibits superior mechanical properties such as surface hardness, etc. and a method of preparing the same. The polyamide-imide film a copolymer of an aromatic diamine, an aromatic dianhydride, and an aromatic dicarbonyl compound, wherein the aromatic diamine and the aromatic dianhydride forms an imide unit; the aromatic diamine and the aromatic dicarbonyl compound forms an amide unit; and the amide unit accounts for 50-70 mol % of 100 mol % of the units of the copolymer, thereby exhibiting transparency and superior mechanical properties including surface hardness.
US11326024B2 Polyamide resin, molded body, laminate, medical device, and polyamide resin production method
A polyamide resin with an excellent balance of mechanical characteristics such as breaking strength and breaking elongation in a solid state, a molded body containing said polyamide resin, a laminate provided with a film or a sheet containing said polyamide resin, a medical device provided with the aforementioned molded body and/or the aforementioned laminate, and a production method of the aforementioned polyamide resin are provided. A polyamide resin is used which contains: a linear aliphatic dicarbonyl unit as unit (a); a linear aliphatic diamino unit as unit (b); at least one of a unit (b) and a unit (c), each of a prescribed structure; and a trivalent unit (e).
US11326023B2 Aromatic polycarbonate resin, method for producing same, and aromatic dihydroxy compound
Provided is an aromatic polycarbonate resin that has not only high fluidity and thin-wall moldability but also excellent hue and transparency. The aromatic polycarbonate resin contains a structural unit derived from an aromatic dihydroxy compound and a carbonate-forming compound. A hydrolysate obtained by hydrolysis of the aromatic polycarbonate resin contains aromatic dihydroxy compounds represented by the following Formulae (2) and (3), and the content of the compound represented by Formula (2) is 250 ppm by mass or less with respect to that of the compound represented by Formula (3), wherein R1 represents an alkyl group having 1 to 24 carbon atoms; R2 and R3 each independently represent a monovalent hydrocarbon group having 1 to 15 carbon atoms; and a and b each independently represent an integer of 0 to 4:
US11326022B2 Multi-armed polymers comprising free-radical-polymerizable monomers and compositions, systems and methods pertaining to the same
In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core, a plurality of polymer segments having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group, wherein the polymer segments comprise one or more free-radical-polymerizable monomers. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.
US11326020B2 Composition for treating three-dimensional object precursor
The present invention is a composition of an agent for treating a precursor of a three-dimensional object for removing a support material from a precursor of the three-dimensional object containing a three-dimensional object and the support material, the composition containing water and a water-soluble compound having a solubility parameter (SP value) calculated by using the Fedors' method of 8 (cal/cm3)1/2 to 13 (cal/cm3)1/2. The present invention can provide a composition of an agent for treating a precursor of a three-dimensional object that is capable of removing the support material quickly and a method for manufacturing a three-dimensional object using the composition of an agent for treating a precursor of a three-dimensional object by a fused deposition modeling system.
US11326018B2 Process for the synthesis of polyoxazolidinone compounds
A method for the production of polyoxazolidinone compounds, comprising the step of reacting an isocyanate compound (A) with an epoxide compound (B) in the presence of a catalyst (C), wherein the isocyanate compound (A) comprises a isocyanate compound (A1) wherein the a isocyanate compound (A1) comprising at least two isocyanate groups (I1≥2), preferred two isocyanate groups (I1=2), wherein the epoxide compound (B) comprises a epoxide compound (B1) and an epoxide compound (B2), wherein the epoxide compound (B2) is different from the epoxide compound (B1) wherein the epoxide compound (B1) comprising at least two terminal epoxide groups (F1≥2), preferred two terminal epoxide groups (F1=2), linked together by a linking group (L1) and the epoxide compound (B2) comprising at least two terminal epoxide groups (F2≥2)), preferred two terminal epoxide groups (F2=2), linked together by a linking group (L2), wherein the linking group (L2) comprises acyclic and covalent bonds to each other free of conjugated multiple bonds within the main chain, wherein the epoxide compound (B2) is present in the epoxide compounds B1 and B2, in an amount of ≥0.01 mol-% to <10 mol-%, preferred 1-9 mol-% more preferred 3-8 mol-% based on the molar ratio the terminal epoxide groups in the epoxide compound (B1) and of the sum of the terminal epoxide groups in the epoxide compound (B1) and terminal epoxide groups in the epoxide compound (B2).
US11326016B1 Stabilized sectionalized containment combination
The invention provides a unique system for providing partition dividers in stowing units (e.g. shelving, trays, and containers). This is accomplished by providing a stowing unit with an adhesive viscoelastomeric thermoset polymer which adhesively restrains a free-standing divider adapted to be removed and repositioned at any desired positon to fit a user's stowing needs. The adhesive polymer is also cohesive and releases both the divider and any stowed items in contact with the polymer via the application of a counteracting removal force sufficient to overcome the adhesive attraction of the polymer. Accordingly, dividers fixedly attached to conventional sectionalized containers are suitably replaced herein by the repositionable divider combination.
US11326015B1 Cyanate ester resin
A method for making a cyanate ester resin includes reacting an arylorganometallic agent with a phosphorous halide in a solvent forming methoxy functionalized triphenylphosphines with one to six meta-methoxy groups. The methoxy functionalized triphenylphosphines with one to six meta-methoxy groups are reacted with an oxidizing agent forming a methoxy functionalized triphenylphosphine oxide including one to six meta-methoxy groups. The methoxy functionalized triphenylphosphine oxide is reacted with a dealkylating agent forming a hydroxy substituted triphenylphosphineoxide including one to six meta-hydroxyl groups. The hydroxy substituted triphenylphosphineoxide is reacted with cyanating reagent and a base forming a substituted triphenylphosphine oxide including one to six meta-cyanate groups. The substituted triphenylphosphine oxide is polymerized forming the cyanate ester resin.
US11326013B2 Block copolymer structure and the preparing method thereof
A block copolymer having the general formula as formula (1): mediator-P2-P1-X, formula (1), and the chemical structural formula is formula (2), in which the mediator in formula (1) and formula (2) is a regulator, which is a conjugated seven-membered ring structure, P1 is a first polymer which may be a conjugated or non-conjugated olefin monomer, R1 is the functional group of P1, n is the number of the monomer of P1, which is a positive integer and the range is 10˜1,500. P2 is a second polymer, m is the number of the monomer of P2, which is a positive integer and the range is 10˜1,500, and X is the end-functional group of the block copolymer.
US11326011B2 Aqueous polymer dispersion and process of making the same
An aqueous dispersion of a multistage polymer and an aqueous coating composition comprising the aqueous dispersion and providing coating films with good scratch resistance and balanced properties.
US11326010B2 Agent for dispersing electrically conductive carbon material, and dispersion of electrically conductive carbon material
Provided is an agent for dispersing an electrically conductive carbon material, in which the agent consists of a polymer which has an oxazoline group in a side chain and which is obtained by using an oxazoline group-containing monomer such as that represented by formula (1) for example, and in which the agent exhibits excellent dispersion of an electrically conductive carbon material and produces a thin film that exhibits excellent adhesion to a current collection substrate when formed into a thin film together with the electrically conductive carbon material. (In the formula, X denotes a polymerizable carbon-carbon double bond-containing group, and R1-R4 each independently denote a hydrogen atom, a halogen atom, an alkyl group optionally having a branched structure having 1-5 carbon atoms, an aryl group having 6-20 carbon atoms, or an aralkyl group having 7-20 carbon atoms.)
US11326003B2 Metallocene catalyst systems with chemically-treated solid oxides for producing ethylene-based plastomers and elastomers
Polymerization processes for producing ethylene-based plastomers and elastomers having densities less than 0.91 g/cm3 utilize a metallocene-based catalyst system containing a chemically-treated solid oxide. These polymerization processes can be conducted in a slurry reactor, a solution reactor, and/or a gas phase reactor. Ethylene polymers produced from the polymerization process can be characterized by a density of less than 0.91 g/cm3, a CY-a parameter of less than 0.2, and a ratio of HLMI/MI of at least 30, or a density less than 0.91 g/cm3, a CY-a parameter from 0.25 to 0.75, and a ratio of Mw/Mn from 2 to 3.
US11326002B2 Polyethylene copolymers and products and methods thereof
A polymer composition may include a polymer produced from ethylene, one or more branched vinyl ester monomers, and optionally, vinyl acetate; wherein the polymer has a number average molecular weight ranging from 5 to 10,000 kDa, and a molecular weight distribution ranging from 1 to 60, obtained by GPC.
US11326000B2 Processing aid and blend employing the processing aid for achieving effective orientation of an extruded film layer and a biaxially oriented film including such film layer
The invention includes a biaxially oriented, multi-layer film including a base layer, at least one intermediate layer and at least one skin layer. The base layer and at least one intermediate layer includes a blend of crystalline polypropylene wax and a high crystallinity polypropylene.
US11325998B2 Method for preparing vinyl chloride-based polymer and vinyl chloride-based polymer prepared therefrom
The present invention relates to a method for preparing a vinyl chloride-based polymer, more specifically, to a method for preparing a vinyl chloride-based polymer through which it is possible to improve an apparent specific gravity of a vinyl chloride-based polymer to be prepared by controlling a surface tension of a polymerization mixture to 46.5 mN/m or more, and thus, to improve an extrusion amount when extruded, whereby a vinyl chloride-based polymer having excellent processing productivity can be prepared.
US11325986B2 Heteropolysaccharides
The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
US11325983B2 Bispecific antibodies
The invention relates to a bispecific antibody comprising a first antigen-binding site capable of binding Factor VII(a) and a second antigen-binding site capable of binding TLT-1, pharmaceutical formulations comprising such bispecific antibodies and uses thereof.
US11325981B2 Bispecific antigen-binding constructs targeting Her2
Provided herein are biparatopic antigen-binding constructs that specifically bind HER2. The biparatopic antigen-binding constructs comprise one antigen-binding moiety that binds to ECD2 of HER2, a second antigen-binding moiety that binds to ECD4 of HER2, and an Fc. At least one of the antigen-binding moieties is an scFv. The biparatopic antigen-binding constructs can be used in the treatment of cancer.
US11325979B2 Treatment of cytokine release syndrome with GM-CSF antagonists
The present invention provides, among other things, a method of treating a subject with infection-induced hyperinflammation comprising administering to the subject a granulocyte-macrophage colony-stimulating factor (GM-CSF) antagonist at a therapeutically effective dose and an administration interval for a treatment period sufficient to improve, stabilize or reduce one or more symptoms of hyperinflammation. The present invention also provides, among other things, a method of inhibiting or reducing cytokine release syndrome (CRS) or acute respiratory distress syndrome (ARDS) in a subject comprising administering to the subject a granulocyte-macrophage colony-stimulating factor (GM-CSF) antagonist at a therapeutically effective dose and an administration interval for a treatment period sufficient to improve, stabilize or reduce one or more symptoms of CRS or ARDS.
US11325977B2 Chimeric antigen receptors against multiple HLA-G isoforms
The present invention relates to chimeric antigen receptors (CAR) against multiple but not all human leukocyte antigen (HLA-G) isoforms. More specifically, the invention concerns CARs that are specific for HLA-G β2M-free or β2M-associated immunosuppressive isoforms respectively.
US11325974B2 Checkpoint blockade and microsatellite instability
Blockade of immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-1 (PD-1) shows promise in patients with cancer. Inhibitory antibodies directed at these receptors have been shown to break immune tolerance and promote anti-tumor immunity. These agents work particularly well in patients with a certain category of tumor. Such tumors may be particularly susceptible to treatment because of the multitude of neoantigens which they produce.
US11325972B2 Methods of treatment of eosinophilic bronchitis with an anti-IL-5 antibody
The present invention relates generally to the methods for the treatment and diagnosis of conditions mediated by IL-5 and excess eosinophil production, and more specifically to mAbs, Fabs, chimeric and humanized antibodies. More particularly, the present invention relates generally to the treatment of eosinophilic bronchitis with an anti-IL-5 antibody or fragment thereof.
US11325971B2 scFv-Fc dimers that bind transforming growth factor-β1 with high affinity, avidity and specificity
An scFv-Fc dimer binds and neutralizes TGFβ1 selectively and with high affinity and avidity. The scFv region may comprise the same VH and VL domains or CDR regions as metelimumab. The unique combination of their smaller size, high selectivity, potency against TGFβ1, and long in vivo half-life makes the scFv-Fc dimers ideal candidates for therapeutic applications.
US11325965B2 Single-domain VH H antibodies directed to norovirus GI.1 and GII.4 and their use
Isolated VHH monoclonal antibodies are disclosed that specifically bind to a Norovirus polypeptide. In some embodiments, the Norovirus is a Genogroup I Norovirus or a Genogroup II Norovirus. In other embodiments, the Norovirus is Norwalk or MD2004 virus. In some embodiments, the monoclonal antibodies specifically bind VP1. Also disclosed are compositions including the disclosed antibodies, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of a Norovirus in a biological sample, or detecting a Norovirus infection. Also disclosed are methods of treating and/or preventing a NoV infection.
US11325963B2 Modified monocytes/macrophage expressing chimeric antigen receptors and uses thereof
The present invention includes methods and compositions for treating cancer, whether a solid tumor or a hematologic malignancy. By expressing a chimeric antigen receptor in a monocyte, macrophage or dendritic cell, the modified cell is recruited to the tumor microenvironment where it acts as a potent immune effector by infiltrating the tumor and killing the target cells. One aspect includes a modified cell and pharmaceutical compositions comprising the modified cell for adoptive cell therapy and treating a disease or condition associated with immunosuppression.
US11325960B2 Method for producing an active hepatocyte growth factor (HGF)
The present invention provides a method for producing active hepatocyte growth factor activator (HGFA) and active hepatocyte growth factor (HGF) without using animal serum. The present invention relates to a method for producing active HGFA without using animal serum. The method is characterized in that it comprises a step of obtaining a culture supernatant comprising pro-HGFA by culturing mammalian cells expressing inactive hepatocyte growth factor activator (pro-HGFA) in a medium without serum, and a step of adjusting the culture supernatant comprising pro-HGFA obtained in the above step to weakly acidic to convert pro-HGFA into active HGFA. The present invention also relates to a method for producing active HGF with HGFA produced by said method.
US11325957B2 Methods and compositions for reducing the immunogenicity of chimeric notch receptors
The present invention relates to methods and compositions for reducing the immunogenicity of chimeric Notch receptors, and specifically to transcription factors useful for controlling gene expression delivered to tissues by such chimeric Notch receptors.
US11325953B2 Protein of ‘dangshan suli’ having function of promoting growth of pollen tube, encoding gene PBRTTS1 and use thereof
Some embodiments of the disclosure provide a protein for promoting the growth of a pollen tube and a gene PbrTTS1 encoding the protein. The amino acid sequence of the protein is shown in SEQ ID No: 1. The nucleotide sequence of the gene PbrTTS1 encoding the protein is shown in SEQ ID No: 2. Other embodiments of the disclosure provide a primer for amplifying the gene PbrTTS1 encoding the protein. The primer includes a forward primer and a reverse primer. The nucleotide sequence of the forward primer is shown in SEQ ID No: 3, and the nucleotide sequence of the reverse primer is shown in SEQ ID No: 4.
US11325950B2 Immunogenic fusion protein
The present invention relates to an immunogenic fusion protein comprising a first amino acid sequence having at least 80% sequence identity with the amino acid sequence of the N-terminal region of a first group B Streptococcus surface protein, which is fused to a second amino acid sequence having at least 80% sequence identity with the amino acid sequence of the N-terminal region of a second group B Streptococcus surface protein. Each of the first and the second group B Streptococcus surface protein is selected from the group consisting of Rib protein, Alp1 protein, Alp2 protein, Alp3 protein, Alp4 protein and AlpC protein. The immunogenic fusion protein further comprises at least one amino acid sequence having at least 80% sequence identity with the amino acid sequence of the N-terminal region of the group B streptococcus surface protein Alp1, Alp2, Alp3 or Alp4. The invention further pertains to an isolated nucleotide sequence encoding the immunogenic fusion protein; a vector; a host cell; an immunogenic product, a vaccine; and a method for preventing or treating a group B Streptococcus infection.
US11325949B2 Insecticidal proteins and methods for their use
Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
US11325948B2 Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
The present disclosure provides methods and compositions for genetically modifying lymphocytes, for example T cells and/or NK cells, in shorter times than previously and/or in whole blood or a component thereof. In some embodiments a lymphodepletion filter assembly is used before or after forming a reaction mixture where lymphocytes are contacted with recombinant retroviral particles in a closed system, to genetically modify the lymphocytes.
US11325943B2 Crystalline salt forms of SBT-20
Disclosed are various crystalline salt forms of L-Phe-D-Arg-L-Phe-L-Lys-NH2.
US11325937B2 Glycoside compound and preparation method therefor, composition, application, and intermediate
The present invention discloses a glycoside compound represented by Formula III, and a preparation method, a composition, use and an intermediate thereof. The glycoside compound provided in the present invention has simple preparation method, can significantly increase the expression of VEGF-A mRNA, and is effective in promoting the angiogenesis. This provides a reliable guarantee for the development of drugs with pro-angiogenic activity for treating cerebral infarction cerebral stroke, myocardial infarction, and ischemic microcirculatory disturbance of lower limbs.
US11325932B2 Organic electroluminescent materials and devices
A compound of Formula I or Formula II wherein Y is selected from the group consisting of O, S, and NRN; and (a) L1 and L2 are the same or different and are each a mono-anionic bidentate ligand; and R is selected from the group consisting of hydrogen, deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carboxylic acid, ether, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, and combinations thereof; or (b) R joins with L1 of the Formulae I or II to form a ring B1 of formula B and formula C, respectively, and L2 is L3 and L3 is a tridentate ligand of formula D wherein ring C, ring D, and ring E are each independently selected from the group consisting a 5-membered aryl, a 5-membered heteroaryl, a 6-membered aryl, and a 6-membered heteroaryl; X1 to X4 are independently selected from C or N, and no more than two of the X1 to X4 is N; Z1 to Z7 are independently selected from C or N; wherein one of Z1, Z4, and Z7 is an anionic donor, and the remaining two are neutral donors; wherein Z2 and Z3 are not both N, and Z5 and Z6 are not both N; and the dotted lines represent coordination to the iridium; wherein each RA to RE represents mono to the maximum allowable substitution, or no substitution; and each RA to RE is independently a hydrogen or a substituent selected from the group consisting of deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carboxylic acid, ether, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, and combinations thereof, wherein any two adjacent substituents RA to RE are optionally joined to form a fused ring.
US11325929B2 Phosphorus-containing compound and preparation and use thereof
The present invention provides a phosphorus-containing compound characterized by being a compound represented by the following structure: the compound is a novel immune cell migration inhibitor. The compound has good hydrophilicity and can be developed into eye drops. The compound has a strong inhibitory ability to immune cell migration and can relieve the symptoms of most dry-eye patients.
US11325923B2 Preparation of siloxanes in the presence of cationic silicon (II) compounds
Siloxanes are prepared by reacting: a compound A with a compound B or a compound A with a compound C or a compound B with a compound C or a compound C alone, in the presence of a compound D at ≥40° C., wherein compound A is a silane or a siloxane having at least one silicon-bonded hydrogen atom, compound B is a silane or a siloxane having at least one silicon-bonded alkoxy moiety, compound C is a silane or a siloxane having at least one silicon-bonded hydrogen atom and at least one silicon-bonded alkoxy moiety, and compound D is a cationic Si(II) compound.
US11325922B2 Process for the preparation of Crisaborole in a stable crystal form
The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
US11325920B2 Antibacterial compounds, compositions thereof, and methods using same
The present disclosure includes novel compounds useful as antimicrobial agents. The present disclosure further includes methods useful. The present disclosure further includes compositions and methods for treating or preventing a bacterial infection. The present disclosure further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms.
US11325919B1 Synthetic novel pyrroloiminoquinone alkaloid and method of use
Aleutianamine represents the first in a new class of pyrroloiminoquinone alkaloids possessing a highly strained multi-bridged ring system, discovered from Latrunculia (Latrunculia) austini Samaai, Kelly & Gibbons, 2006 (class Demospongiae, order Poecilosclerida, family Latrunculiidae) recovered during a NOAA deep-water exploration of the Aleutian Islands. Aleutianamine exhibited potent and selective cytotoxicity toward solid tumor cell lines including pancreatic cancer (PANC-1) with an IC50 of 25 nM and colon cancer (H116) with IC50 of 1 μM.
US11325913B2 Compounds and methods for the treatment of malaria
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of malaria.
US11325909B2 Crystalline 2-amino-2-(hydroxymethyl)propane-1,3-diol salt of 4-(4-(1-isopropyl-7-OXO-1,4,6,7-tetrahydrospiro[indazole-5,4′-piperidine]-1′-carbonyl)-6-methoxypryridin-2-YL)benzoic acid
The invention provides the tris salt of 4-(4-(1-isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4′-piperidine]-1′-carbonyl)-6-methoxypyridin-2-yl)benzoic acid as a crystalline anhydrous or tri-hydrate; as well as polymorphs, pharmaceutical compositions, dosage forms, and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase (ACC) enzyme(s) in an animal.
US11325907B2 Crystal form of 1H-imidazo[4,5-b]pyridine-2(3H)-one compound and preparation process therefor
Disclosed are a crystal form of 1H-imidazo[4,5-b]pyridine-2(3H)-one compound and a preparation process therefor, and use of the crystal form in the manufacture of a medicament for treating a disease associated with PDE4 receptor.
US11325906B2 Chemical compounds
The present invention relates to azaquinolone compounds of Formula (I), and their use in medicine.
US11325904B2 Tropinol esters and related compounds to promote normal processing of APP
In various embodiments, compositions and methods are provided for treatment and/or prevention of amyloidogenic diseases. In certain embodiments, the methods entail administering an effective amount of a tropinol ester to a subject in need thereof for prophylactic or therapeutic effect. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In certain embodiments, methods of reducing the risk, lessening the severity, or delaying the progression or onset of a disease characterized by beta-amyloid deposits in the brain of a mammal are also provided. In certain embodiments, methods of directly or indirectly inhibiting the C-terminal cleavage of APP resulting in the formation of APP-C31 peptide and APPneo (AP-P664) in a mammal are provided.
US11325902B2 Benzenesulfonamide compounds and their use as therapeutic agents
This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy and/or epileptic seizure disorders.
US11325896B2 Antagonists of the muscarinic acetylcholine receptor M4
Disclosed herein are substituted 2-azaspiro[3.3]heptane compounds of formula (I′), which may be useful as antagonists of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders using the compounds and compositions.
US11325895B2 Crystals of tetrahydronaphthyl urea derivative
Provided are type I, III, V and VI crystals of 1-((1R,2R)-2-hydroxy-4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(5-methyl-6-(2-methylpyrimidin-5-yl)-2-phenylpyridin-3-yl)urea which are useful as bulk pharmaceutical crystals. Also provided are type I, III, V and VI crystals of 1-((1R,2R)-2-hydroxy-4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(5-methyl-6-(2-methylpyrimidin-5-yl)-2-phenylpyridin-3-yl)urea having excellent TrkA inhibitory effect, medicines and medicinal composition containing these crystals, and a method for producing these crystals.
US11325894B2 Upgrading ketoacid
The present invention relates to a method using a specific catalyst for upgrading ketoacid to intermediates for fuel and chemical industry, intermediates obtained by the method and to their use.
US11325893B2 Hydrofluoroethers and methods of using same
A compound is represented by the following general formula (I): (I) wherein each of Rf1 and Rf2 is, independently, F, CF3, C2F5, C3F7, or C4F9, with the proviso that if either of Rf1 and Rf2 is fluorine, then the other is not fluorine; Rf3 is F, CF3, C2F5, C3F7 or CF(CF3)2; Rf4 is F, CF3, C2F5, C3F7 or CF(CF3)2; and Rh is CH3 or C2H5.
US11325892B2 Compounds and methods for treating cancer
This document provides compounds, compositions, and methods for treating cancers including renal cancer (e.g., renal cell carcinoma) as well as ovarian, breast, prostate, colon, pancreatic, bladder, liver, lung, and thyroid cancers and melanoma. For example, compounds, compositions, and methods for using one or more inhibitors of SCD1 to treat renal cell carcinoma (e.g., clear cell renal cell carcinoma (ccRCC)), thyroid cancer, or liver cancer; or to increase the efficacy of treatment for the same.
US11325887B2 Methods for forming peroxyformic acid and uses thereof
The present invention relates generally to methods for forming peroxyformic acid, comprising contacting formic acid with hydrogen peroxide. The methods for forming peroxyformic acid can include adding formic acid with a relatively lower concentration of hydrogen peroxide, or adding formic acid to a peroxycarboxylic acid composition or forming composition to react with hydrogen peroxide in the compositions. The present invention also relates to peroxyformic acid formed by the above methods. The present invention further relates to the uses of peroxyformic acid for treating a variety of targets, e.g., target water, including target water used in connection with oil- and gas-field operations. The present invention further relates to methods for reducing or removing H2S or iron sulfide in the treated water source, improving clarity of the treated water source, or reducing the total dissolved oxygen or corrosion in the treated water source, using peroxyformic acid, including peroxyformic acid generated in situ.
US11325886B2 Amide compounds, pharmaceutical compositions thereof, and methods of using the same
Amide compounds are disclosed. Also disclosed are pharmaceutical compositions comprising the compounds as well as methods of treating neurodegenerative diseases that involve administering the compounds or pharmaceutical compositions to a subject.
US11325883B2 Functionalized N,N-dialkylamino phenyl ethers and their method of use
Pharmaceutical compositions of the invention comprise functionalized N,N-dialkylamino phenyl ethers derivatives having a disease-modifying action in the treatment of diseases associated with lysosomal storage dysfunction that include Gaucher's disease, and any disease or condition involving lysosomal storage dysfunction.
US11325876B2 Process for producing a chlorinated C3-6 alkane
Disclosed is a process for producing a chlorinated C3-6 alkane comprising providing a reaction mixture comprising an alkene and carbon tetrachloride in a principal alkylation zone to produce chlorinated C3-6 alkane in the reaction mixture, and extracting a portion of the reaction mixture from the principal alkylation zone, wherein:a) the concentration of the chlorinated C3-6 alkane in the reaction mixture in the principal alkylation zone is maintained at a level such that the molar ratio of chlorinated C3-6 alkane:carbon tetrachloride in the reaction mixture extracted from the alkylation zone does not exceed 95:5 when the principal alkylation zone is in continuous operation; and/or b) the reaction mixture extracted from the principal alkylation zone additionally comprises alkene and the reaction mixture is subjected to a dealkenation step in which at least about 50% or more by weight of the alkene present in the reaction mixture is extracted therefrom and at least about 50% of the extracted alkene is fed back into the reaction mixture provided in the principal alkylation zone; and/or c) the reaction mixture present in the principal alkylation zone and extracted from the principal alkylation zone additionally comprises a catalyst, and the reaction mixture extracted from the principal alkylation zone is subjected to an aqueous treatment step in which the reaction mixture is contacted with an aqueous medium in an aqueous treatment zone, a biphasic mixture is formed and an organic phase comprising catalyst is extracted from the biphasic mixture.
US11325874B2 Method for preparing a linear alpha olefin including oxygen removal from the feed
Provided is a method for preparing a linear alpha olefin using a chromium-based catalyst, including the steps of: removing oxygen impurities by contacting an olefin with an oxygen adsorbent; injecting the olefin from which the oxygen impurities are removed; a chromium-based catalyst into a reactor; and oligomerizing the olefin in the reactor.
US11325872B2 Concentrated aqueous suspension of microfibrillated cellulose comprising salts for plant nutrition
A concentrated aqueous suspension of microfibrillated cellulose (MFC) comprising salts for plant nutrition, the concentrated aqueous suspension comprises microfibrillated linear polymers of D-glucose molecules homogenized through a fibrillation process (cellulose microfibers), calcium ions, sulfate ions and other substances for plant nutrition, being the concentration of calcium ions and sulfate ions in excess of the concentration corresponding to the solubility of calcium sulfate in water and being the proportion of microfibrillated cellulose (MFC) within a range of 1% and 99% w/w of the suspension.
US11325866B2 Aluminum nitride sintered body, method of making the same, and semiconductor manufacturing equipment component using aluminum nitride sintered body
An aluminum nitride sintered body for use in a semiconductor manufacturing apparatus is provided. The aluminum nitride sintered body exhibits, in a photoluminescence spectrum thereof in a wavelength range of 350 nm to 700 nm obtained with 250 nm excitation light, a highest emission intensity peak within a wavelength range of 580 nm to 620 nm.
US11325861B1 Multi-solid waste activated concrete with high-silicon iron ore tailings and preparation method thereof
Multi-solid waste activated concretes with high-silicon iron ore tailings and preparation methods thereof are disclosed. In at least some embodiments, the concrete is prepared from raw materials including 360-380 kg/m3 of a cement, 30-40 kg/m3 of fly ash, 30-40 kg/m3 of a modified ultrafine sand of high-silicon iron ore tailings, 930-950 kg/m3 of a waste stone of tailings, 870-930 kg/m3 of a fine sand of tailings, 160-170 kg/m3 of water, and 4-8 kg/m3 of an additive.
US11325860B2 Laser-colored sapphire material
A colored sapphire material and methods for coloring sapphire material using lasers are disclosed. The method for coloring the sapphire material may include positioning the sapphire material over an opaque substrate material, exposing the opaque substrate material to a laser beam passing through the sapphire material to impact the substrate material, and inducing a chemical change in a portion of the sapphire material exposed to the laser beam. The method may also include creating a visible color in the portion of the sapphire material as a result of the chemical change. The colored sapphire material may include a first transparent portion, and a second, colored portion substantially surrounded by the first portion. The second, colored portion may have a chemical composition different than that of the first portion.
US11325855B2 Glass compositions with improved chemical and mechanical durability
The embodiments described herein relate to chemically and mechanically durable glass compositions and glass articles formed from the same. In an embodiment the glass composition may include from about 67 mol. % to about 80 mol. % SiO2; from about 3 mol. % to about 13 mol. % alkaline earth oxide; from about 2 mol. % to about 10 mol. % Al2O3; from about 2 mol. % to about 18 mol. % alkali oxide, wherein the alkali oxide comprises non-zero amounts of Na2O; from 0 mol. % to about 4 mol. % B2O3; and from about 0.01 mol. % to about 1 mol. % of a fining agent.
US11325853B2 Sewage treatment system
A sewage treatment system includes dehydration means to dehydrate the received surplus sludge and/or the received return sludge; a microbial material production device configured to supply oxygen to the dehydrated sludge received from the dehydration means while maintaining the temperature of the dehydrated sludge to subject the dehydrated sludge to aerobic fermentation, thereby producing a microbial material; water feeding means configured to feed water from any part of the sewage treatment system to the after-mentioned microbe activation device; a microbe activation device configured to receive the microbial material from the microbial material production device, and supply the water from the water feeding means to the received microbial material; and oxygen supply means configured to supply oxygen to the sewage at any position of the relay pump station; wherein the sewage is sent from the relay pump station to the sewage treatment facility.
US11325843B2 Fixture and method for purifying a drinking water purification system
The invention relates to a fixture and a method for cleaning a drinking water purification system including the following steps: removal of a filter cartridge from a cartridge holder of a filtering unit in a cold water line, insertion of a connection adapter into the cartridge holder to form a fluid connection with the cold water line, connection of a connecting piece of a hot water line to the connection adapter, heating of water with a heater interconnected with the hot water line, delivery of heated water via the connecting piece of the hot water line and the connection adapter into the cold water line.
US11325841B2 Preparation method of indium oxide with stable morphology and application thereof
A preparation method of indium oxide with stable morphology includes: (1) mixing indium oxide powder and bismuth oxide powder according to a mass ratio of 1:0.1-0.5 to obtain a powder mixture; (2) putting the powder mixture into a ball mill for ball milling at room temperature to obtain a uniform powder mixture; (3) putting the obtained uniform powder mixture into a muffle furnace and calcining at 700-1000° C.; and (4) obtaining the indium oxide with cubic stable morphology after the muffle furnace naturally cools to room temperature. The method has advantages of simple synthesis process, short synthesis period, high sample yield, no need of complicated equipment, and morphology of the obtained indium oxide can be maintained after being heated at a high temperature within 1000° C. for 2 hours. An electrochemical sensor prepared by using the indium oxide obtained by the method has better selectivity to nonane.
US11325839B2 Zinc oxide particle preparation and methods of use
A method of using ZnO particles for the treatment of colon cancer and a method of using the particles for reducing the concentration of an organic contaminant in an aqueous solution is described. The ZnO particles are substantially spherical and may have nanopetals that provide a nanoflower morphology. The synthesis and characterization of the ZnO particles is also discussed.
US11325838B2 Surface-modified metal compound particles, and method for producing surface-modified metal compound particles
These surface-modified metal compound particles have metal compound particles the surfaces of which are modified by: at least one first carboxylic acid selected from the group consisting of a methacrylic acid, an acrylic acid, and a propionic acid; and at least one second carboxylic acid selected from the group consisting of a C6-C16 fatty acid and a C7-C32 monovalent carboxylic acid having at least one benzene ring, wherein at least a portion of the first carboxylic acid is a carboxylic acid type in which a hydrogen atom of the carboxy group is not dissociated as an ion.
US11325837B2 System, process and related sintered article
A process of forming a sintered article includes heating a green portion of a tape of polycrystalline ceramic and/or minerals in organic binder at a binder removal zone to a temperature sufficient to pyrolyze the binder; horizontally conveying the portion of tape with organic binder removed from the binder removal zone to a sintering zone; and sintering polycrystalline ceramic and/or minerals of the portion of tape at the sintering zone, wherein the tape simultaneously extends through the removal and sintering zones.
US11325834B2 Process to produce an engineered carbon
A process for the conversion of hardwood and bamboo to engineered carbon is disclosed. The biomass feedstock of hardwood and bamboo is placed into a holding canister, and the holding canister is lowered into the sealable reactor vessel. The biomass feedstock is ignited, and superheated stream and/or water is metered, or alternately steam is created in situ by introduction of water, into the process. The process is controlled by supplying compressed air and steam, or in situ water, and releasing process gases. The process is performed in an oxygen deprived state. Steam, or in situ water, is injected at the end of the cycle to end the thermal conversion and clean the resulting engineered carbon.
US11325827B2 Pore formation in a substrate
Methods are provided for manufacturing well-controlled, solid-state nanopores and arrays thereof. In one aspect, methods for manufacturing nanopores and arrays thereof exploit a physical seam. One or more etch pits are formed in a topside of a substrate and one or more trenches, which align with the one or more etch pits, are formed in a backside of the substrate. An opening is formed between the one or more etch pits and the one or more trenches. A dielectric material is then formed over the substrate to fill the opening. Contacts are then disposed on the topside and the backside of the substrate and a voltage is applied from the topside to the backside, or vice versa, through the dielectric material to form a nanopore. In another aspect, the nanopore is formed at or near the center of the opening at a seam, which is formed in the dielectric material.
US11325825B2 Valve for a gravity-feed silo tank fueling system
A fleet refueling silo tank system gravity feeds fuel through hoses to fleet units without requiring pressurizing pumps. A specialized valve at the fleet unit fuel tank prevents vapor escape and admits fuel at low, gravity-feed pressures. The valve includes a valve body with an upper end and a lower end, the upper end adapted to engage a cap which affixes the valve body to the fuel tank fill mouth. Below the cap, a fuel cut-off plunger and seat selectively interrupt fuel flow through the mouth by responding to a buoyant float extending coaxially beneath the valve body and into the fuel tank. Linkage coupled to the plunger extends through the valve body to the float, and roller bearings within the valve body engage a shaft extending from the float coaxially into the lower end of the valve body.
US11325822B2 Water dispenser and pure water producing apparatus
A water dispenser which is connected to a pure water source and used for dispensing pure water includes: an arm mounting unit; a water dispensing gun including a nozzle for discharging pure water; a holding unit for holding the water dispensing gun; and at least two arms connecting the holding unit to the arm mounting unit. The at least two arms constitute a parallel link mechanism in which a trajectory of each arm when the at least two arms move is within the same vertical plane.
US11325816B2 Independent drive motors for machinery positioning apparatus having independent lifting motors
A lifting apparatus and controller therefore, where the lifting apparatus includes independently driven lifting columns and independently driven wheels that are controlled by a controller having a number of sensors such as limit sensors, position sensors, rotation sensors, laser sensors, torque sensors and the like. The independent motors for lifting and driving may also be removed easily to provide for improved servicing and maintenance. The various sensor signals are used to calculate, coordinate and calibrate the apparatus for precise and safe movement by the motors in order to perform lifting and positioning operations, for example rail car repair and service.
US11325812B2 Damping device for main rope
A damping device for a main rope suspending a car of an elevator includes a coupled, a first pulley and a drive. The coupler is attached to the main rope above the car, and is configured to be pulled, in response to vibrations of the main rope, with a damping rope so as to suppress vibrations of the main rope. The first pulley is supported at a same height as a height of the coupler. The drive is configured to suppress vibration of the main rope by pulling a first damping rope coupled to the coupler and passing over the first pulley.
US11325807B2 Line handling device for letting out, winding up, and locking a line
A line-handling device is for letting out, winding up and locking a line. The line-handling device has: a first handle; a substantially flat reel which is rotatable relative to the first handle; a line-guiding part which is fixed relative to the first handle; a locking mechanism for locking the reel in a non-rotatable position; and an attachment element for a tautening device, the reel being displaceable relative to the first handle parallel to the rotational axis of the reel. A line-handling system is for suspending a line between two anchoring points and a method is for suspending a line between two anchoring points.
US11325806B2 Drop stitch tethers alignment
The present disclosure relates to a method performed by an alignment system for aligning tethers of a drop stitch fabric prior to feeding the drop stitch fabric to a drop stitch fabric processing machine. The alignment system feeds a drop stitch fabric having a first layer and a second layer tethered by drop stitch tethers, wherein the first layer is moving with a first velocity and the second layer is moving with a second velocity. The disclosure also relates to an alignment system in accordance with to the foregoing.
US11325803B2 Gluing device of an end edge of a log
A gluing device of an end edge of a log including an introduction assembly into the gluing device of a log, a handling assembly for a log associated to detection device of the end edge and including a pair of rolls for advancement and holding in rotation of the log, a glue dispensing assembly and a transfer assembly of the log including a transfer plane positioned downstream of the lower handling roller. The glue dispensing assembly is placed in series between the lower handling roll and the transfer plane and includes a transverse tank for the glue, housing cyclically movable glue transfer members. The transverse tank is provided with an upper cover provided with a plurality of openings provided in succession side by side at a set distance along a transverse row. The movable glue transfer members include a plurality of tips provided in succession along a transverse row, alternatively projecting through the relevant openings and retracted within the transverse tank because of the cyclical movement.
US11325798B2 Feeding device and sheet processing device with the same
A feeding device comprises a suction feeding unit having a belt for feeding a sheet in a suction state and a belt driving unit, a sheet detection sensor, and a control unit. The control unit controls the belt drive unit so as to feed the sheet in a feeding direction at a first speed. If the sheet does not arrive at the sheet detection sensor, the control unit controls the belt drive unit so as to execute a low-speed feeding of moving the belt in the feeding direction at a second speed lower than the first speed or so as to execute a reverse feeding of moving the belt in a reverse feeding direction opposite to the feeding direction.
US11325795B1 Systems and methods for modifying loading dock environments to enable trailer swing doors to open inside of a loading dock
Systems and methods for the modification of loading dock environments are provided that allow trailers and shipping containers on chassis' to park at a loading dock with closed doors and have these doors opened into the loading dock environment and resealed while the trailer remains at the loading dock.
US11325792B2 Loading station for a pocket conveyor
A loading station for a pocket conveyor having two conveying lines. The loading station has a receiving section for receiving pockets for each conveying line; a receiving section for objects, with which the pockets are to be loaded; and a device for each conveying line, into each of which an empty pocket to be filled can be introduced. In addition, the loading station has a moving unit for moving the devices from a receiving section for objects to one of the receiving sections for receiving pockets, and back again. The loading station is also designed to alternately load the pockets of the first conveying line and the pockets of the second conveying line.
US11325789B2 Sorting facility
A sorting facility for sorting articles by a plurality of connected conveyance carriages. The sorting facility includes a supervisory controller managing a position of each of the conveyance carriages, a trigger sensor detecting each of the conveyance carriages, and a belt conveyor provided on each of the conveyance carriages. The supervisory controller identifies each of the conveyance carriages that should deliver the articles to the chute based on the managed position of each of the conveyance carriages. The supervisory controller instructs the belt conveyor provided in each of the conveyance carriages identified to start a delivery operation of each of the articles at timing when each of the conveyance carriages identified is detected by the trigger sensor.
US11325786B2 Guide profile and conveying system
A guide profile and a conveying system are disclosed. The conveying system is designed with a guide profile of this type. A slide bar of the guide profile is provided with an articulated leg so that it is possible to change the slide bar on the already installed conveying system.
US11325785B2 Article conveying facility
An article conveying facility in which an article is conveyed by a conveyance carriage travelling on a pair of left and right rails provided along a conveyance path. The article conveying facility includes a carriage driving apparatus that drives the conveyance carriage by utilizing a frictional force generated by contact with the conveyance carriage, and sensors that detect floating of the conveyance carriage with respect to the rails. The conveyance carriage includes a fin that contacts the carriage driving apparatus. The fin is provided so as to extend along the travelling direction of the conveyance carriage, at a lower position than the position of an upper surface of the rails. The sensors detect floating of the conveyance carriage with respect to the rails by detecting the fin.
US11325780B2 Method and device for sorting cargo
A method and a device for sorting cargo. The method includes: acquiring a to-be-allocated order; determining, for each target sorting unit, at least one of: a number of to-be-sorted orders of the target sorting unit, a number of types of to-be-sorted cargo, or a coincidence number of types of cargo between the target sorting unit and the to-be-allocated order; selecting a target sorting unit based on at least one of following items of each target sorting unit: the number to-be-sorted orders, the number of types of to-be-sorted cargo, or the coincidence number of types of cargo; and allocating the to-be-allocated order to the selected target sorting unit, such that the selected target sorting unit sorts out the cargo indicated by the to-be-allocated order.
US11325779B2 Smart locker automated transfer system and method
A smart locker automated transfer system includes one or more lockers, a transfer system, and an autonomous delivery robot. Each locker includes a retractable base plate configured to hold the package. The transfer system may include a rack and rail system, one or more conveyor belts, or both. The autonomous delivery robot may be configured to receive the package from the transfer system. The autonomous delivery robot may be configured to deliver the package to a destination.
US11325777B2 Systems and processes for space management of three dimensional containers including biological measurements
Systems and methods for remote monitoring of a container are disclosed. The system includes at least one data collector configured to collect data corresponding to a physical attribute of the container, a wireless transmitter in communication with the at least one data collector and configured to transmit the data corresponding to a physical attribute of the container to a location remote from the location of the container, a server in communication with the wireless transmitter to receive and process the data corresponding to a physical attribute of the container, and a physical attribute analysis engine in communication with the server to receive the data corresponding to a physical attribute of the container and calculate a current value for the physical attribute based upon the received data.
US11325772B2 Box defining walls with insulation cavities
A method of assembling a box from a blank including obtaining a blank including a plurality of outer side panels, the outer side panels connected to each other by a plurality of fold lines, a plurality of outer bottom panels each joined to each of the outer side panels by a fold line, a plurality of connecting strips each joined to each of the outer side panels by a fold line, a plurality of inner side panels each joined to each of the connecting strips by a fold line, and a plurality of inner bottom panels each joined to each of the inner side panels by a fold line; and joining the outer side panels at opposite ends such that the outer side panels form a ring.
US11325764B2 Carton for articles
A carton for containing a plurality of articles. The carton can comprise a plurality of panels that extends at least partially around an interior of the carton. The plurality of panels can comprise a bottom panel, a top panel, and a side panel. At least two end flaps are respectively foldably attached to respective panels of the plurality of panels. The at least two end flaps can at least partially form a closed end of the carton, and the at least two end flaps can comprise a first end flap foldably connected to at least one panel of the plurality of panels at a first fold line and a second end flap foldably connected to the at least one panel at a second fold line. The second fold line is oblique relative to the first fold line.
US11325756B2 Child resistant pail
An improved lid and pail combination provides a child resistant connection for use with pails.
US11325755B2 Pouring spout fitment for flexible container
Flexible package fitments for use with detachable dispensing systems are provided. Pouring spout fitments configured to be attached to the inner surface of flexible containers are also provided. The detachable dispensing systems and pouring spout fitments include a hollow rigid member (115) and an extendible spout (121) disposed within and at least partially attached to the hollow rigid member and selectively positionable between a recessed position and, alternatively, an extended position, in which the extendible spout is configured to dispense a pourable material from the container through a distal opening when the fitment is attached to a flexible package. Material containers are also provided that include the fitments described herein.
US11325752B2 Bottle cap and bottle
A bottle cap is disclosed. The bottle cap includes a cap body having a cover plate and a cylinder part integral with the cover plate. A stopper member protrudes from an inner surface of the cover plate. The stopper member includes a sealing part supported by a support structure integral with the cover plate. An annular guiding plate protrudes from a sidewall surface of the cylinder part and is inclined toward the stopper member to engage with the sealing part.
US11325749B2 Container with removable tray
The present invention relates to a container including a container body with a removable tray wherein the container can house at least two materials that must be kept separate until use. The container also may have upwardly extending fingers in the removable tray for securing a material.
US11325748B2 Impact-protection device capable of being provided on a bottle
A device for protecting against shocks for a glass bottle is presented, having a body, a bottom and a distal portion successively comprising from the body, a shoulder, a collar and a neck, said device comprising a first cup engaging with the bottom and a second cup engaging with the shoulder, each of the cups having a projecting portion for damping shocks, along a transversal plane, beyond a zone of a larger diameter of the bottle. The projecting portion of at least one from among the first and the second cups includes a plurality of damping pads spaced apart from one another.
US11325747B2 Bulk container with interlocking features
A container having interlocking features is provided. The container includes protrusions on the upper edges of the side wall panels and base wall panels, and notches in the runners/feet for receiving the protrusions. The runners and/or feet extend to the outer perimeter of the container so they can rest on an upper edge of a like container, and do not include a recess from the outer perimeter.
US11325744B2 Carton box with fast packaging function
A carton box includes a main body and at least one fastening module removably mounted on the main body. The main body includes two first face boards and two second face boards. One of the first face boards is provided with a first movable plate. The other one of the first face boards is provided with a second movable plate. The main body is provided with at least one locking slot. The at least one fastening module includes a first fastener member mounted on the second movable plate and a second fastener member located in the at least one locking slot of the main body. The second fastener member is detachably connected with the first fastener member.
US11325740B2 Straight consistent body scores on plastic corrugated boxes and a process for making same
The invention is directed to straight, consistent body scores on plastic corrugated boxes and a process for making the body scores.
US11325738B1 Drink stacker storage systems
According to an aspect of the present invention, a stackable storage rack system suitable for storing containers is provided. The system includes a base. The system also includes a plurality of compartments positionable within the base, wherein the compartments form a cavity within the base and have an opening on a top of the base designed to store containers. The system further includes at least 4 legs, wherein a top of the legs are connected to a bottom of the base at four separate bottom corners of the base. Additionally, the system includes an operational space formed by stacking at least two storage racks one on top of another wherein users of the system can retrieve containers from the bottom storage rack without interference from the top storage rack.
US11325735B1 Methods of using adjustable packaging
A packing insert includes a panel that defines a periphery, a location inward of the periphery, and a plurality of flaps each defining an outer end and an inner end such that each flap extends inwardly from its outer end to its inner end. Each of the flaps is foldable about its outer end so that the flaps collectively define a void. A first one of the flaps has a second outer end spaced outwardly from the outer end of the first flap. The panel defines at least one frangible portion between the outer end and the second outer end of the first flap. The first flap is selectively foldable about 1) its outer end so as to at least partially define the void, and 2) its second outer end, after breaking the at least one frangible portion, so as to increase a size of the void.
US11325734B2 Heat shrinking apparatus in shrink packaging machine
A heat shrinking apparatus 1 includes: a conveyance unit 11 conveying a package 3 obtained by wrapping an object(s) 5 with a heat-shrink film 4; an endless belt 21 disposed below a conveying surface of the conveyance unit, rotating along a conveying direction of the conveyance unit; and a hot air jet unit 19(20) jetting out hot air from an inside to an outside of a belt surface of the endless belt facing the conveying surface, wherein: the endless belt has a hot air passing portion 30 extending in a belt width direction; the hot air jet unit jets out the hot air toward the conveying surface through the hot air passing portion; and the endless belt rotates following a movement of the package so that a seal portion(s) 6a(6b) provided at a front end and/or a rear end of the package is/are heat-shrunk with the hot air.
US11325732B2 Packaging machine and method for making capsules
A packaging machine for making capsules of the type including a container having an inlet opening and a bottom and at least one substantially disc-shaped element associated with the container, including a movement system by which the containers are directed along a predetermined path in a feed direction; a movement means by which a continuous web for defining the disc-shaped elements is moved along a second predetermined path; a cutoff station where the disc-shaped elements are cut from the continuous web and which is positioned along the second predetermined path and an associating station where the disc-shaped elements are associated with the containers and which is positioned along the predetermined path; the associating station is distinct from the cutoff station and the machine includes a transfer system by which the disc-shaped elements are transferred from the cutoff station to the associating station.
US11325727B2 Converging/diverging magnetic nozzle
A magnetic nozzle having a converging/diverging contour shape that converts the thermal energy of a propellant into directed kinetic energy, but uses magnetic fields instead of a physical boundary to direct the flow of particles.
US11325726B2 Method and apparatus for spacecraft gyroscope scale factor calibration
A method and apparatus for estimating gyro scale factor during normal spacecraft operations, using small attitude motions that are compliant with mission pointing accuracy and stability requirements and a signal processing method that specifically detects the intentionally induced motions. This process increases operational availability by avoiding the need to take the spacecraft offline for large calibration maneuvers.
US11325724B2 Coupling module for a passenger boarding bridge with suspended floor
A coupling module for forming an interface between a cabin of an air passenger bridge and an aircraft. The coupling module has a projecting roof and a floor arrangement spanned by the projecting roof. The end face of the floor arrangement facing the cabin is fastenable to the cabin by at least one releasable fastening means, and the floor arrangement is connectable spaced apart from its end face to the cabin by at least one anchorage means.
US11325722B2 Wireless engine monitoring system for environmental emission control and aircraft networking
A wireless engine monitoring system for an aircraft engine includes a housing and wireless transceiver that receives engine data, including engine data relating to environmental engine emissions. A processor processes the engine data and generates an alarm report when the environmental engine emissions exceed a threshold.
US11325717B2 Aircraft nacelle including a link between a conduit of an air inlet and a conduit of an engine
An aircraft nacelle including a conduit rigidly connected to an air inlet and a conduit rigidly connected to an engine, a link between the conduit rigidly connected to the air inlet and the conduit rigidly connected to the engine. The link includes a sleeve that receives one end of a first conduit and is rigidly connected to a second conduit, and linking elements that link the sleeve and the first conduit and that are distributed about the entire circumference of the nacelle, each linking element having a threaded stem oriented in a radial direction and being configured to enable tightening from inside the first conduit.
US11325713B2 Aircraft ice protection system and method
Ice protection systems of aircraft and related methods are disclosed. In one embodiment of the present invention, the system includes a gas-discharge lamp and an electric power source. The gas-discharge lamp is configured to emit infrared radiation toward an inner surface of an aircraft skin. The electric power source is operatively connected to the gas-discharge lamp.
US11325711B2 Seat unit structure, seat unit, and attachment method thereof
An object of the present invention is to provide a seat unit structure, a seat unit, and an attachment method thereof in which component reinstallation does not arise when the seat unit is attached in an aircraft. One representative seat unit structure according to the present invention relates to a seat unit structure configured to support a seat, wherein the structure has a lower structure having a monocoque structure and defines an outermost shell in at least one direction of the seat unit. That is, the member mounted in the one direction of the seat unit can be stored inside the outermost shell of the structure. In addition, the one direction is the width direction of the airframe.
US11325709B1 Upper shell including an actuatable pocket for an aircraft seat
An upper shell for an aircraft seat may include a main body, and an upper pocket. The upper pocket may include a pocket flap coupled to the main body via at least one pocket flap hinge. The upper pocket may include a pocket cavity defined within the main body. The pocket cavity may be accessible following an actuation of the pocket flap into a pocket flap open position via the at least one pocket flap hinge. The pocket flap may be configured to cover at least a portion of the pocket cavity when the pocket flap is in a pocket flap closed position. The upper shell for the aircraft seat may include a personal electronic device (PED) holder assembly with a PED cavity defined within an area of the upper pocket, and a PED holder configured to fit within the PED cavity when in a PED holder closed position.
US11325707B2 Automation system and method for operating an automation system
An automation system, comprising a control device for controlling at least one machine, and at least one unmanned aircraft. The control device is designed to control the unmanned aircraft to support an operation of the machine.
US11325704B2 Unmanned automated hook coupling device
Disclosed is an unmanned automated hook-fastening device including a device coupler, a propulsion unit, a transmitter, a receiver, hook pliers, and an unloading transmitter. The propulsion unit adjusts the position of the hoisting unit with respect to the object, on the basis of the position signal transmitted by the transmitter and received by the receiver, and adjusts the position of the hoisting unit coupled to the object, on the basis of the position signal transmitted by the unloading transmitter and received by the receiver. It is possible to easily track the position of a hook of the object to be hoisted, automatically fasten the hook pliers to the hook, and automatically fasten the hook to a crane without a monitoring system.
US11325702B2 Tethered aerial drone system
Methods and systems are described for an aerial drone system including a drone system controller, at least one working drone (101), and a plurality of support drones (103). The working drone (101) is operated by the drone system controller (125) to adjust a position of the working drone (101). A tether line (105) coupled to the working drone (101) provides electrical power to the working drone (101). The support drones (103) are each coupled to the tether line (105) at a different location along the tether line (105) forming a tethered aerial drone system. Each support (drone 103) supports a portion of the weight of the tether line (105) and is operated by the drone system controller (125) to adjust the position of the tether line (105) by adjusting the position of one or more of the support drones (103).
US11325701B2 Aircraft propulsion system, method of manufacture and use thereof
The present invention provides a propulsion system for an aircraft. The system includes one or more thrust producing portions, wherein the one or more thrust producing portions include one or more duct means. The duct means are at least partially formed or defined by two or more substantially parallel wall members. At least one flapping or waving wing member is provided, at least partially located or positioned substantially within the one or more duct means, wherein the flapping or waving motion of the at least one wing member creates thrust, enabling the aircraft to fly in use.
US11325700B2 Hypersonic waverider stream surface actuation for variable design point operation
A method of designing a hypersonic vehicle includes selecting a shock shape; tracing a leading edge along the shock shape; selecting a base plane defining endpoints of the leading edge and rearwardly displaced from a front of the leading edge; and tracing stream surfaces back from the leading edge along the shock to the base plane in order to define an upper surface and a lower surface, wherein the upper and lower surfaces and base plane enclose a volume representing internal volume of the hypersonic vehicle. The lower stream surface is controllably morphable.
US11325697B1 VTOL flying wing and flying wing aircraft
A vertical take-off and landing (“VTOL”) aircraft has at least two flying wings (“FW”) with each FW equipped with multiple transverse-radial propellers or a propulsion system for producing a lift force and thrust force on the stationary or non-stationary FW. This VTOL/FWA is capable of exchanging payloads horizontally, as well as vertically, with a stationary or a moving object. In particular, the VTOL/FWA can “walk” on a building wall to adjust and anchor its position in order to rescue people from a high-rise-building window horizontally.
US11325696B2 Delivery rotary-wing aircraft
A delivery rotary-wing aircraft has a plurality of rotary wings, a central portion to which a plurality of arms for supporting the rotary wings are connected, a first mounting portion for loading a package, a second mounting portion which is located on the opposite side to the first mounting portion as viewed from the central portion, a first supporting member for coupling the first mounting portion with the central portion, and a connection portion between the central portion and the first supporting member. The center point of lift occurring in the rotary-wing aircraft with the rotation of the plurality of rotary wings and the center point of gravity of the rotary-wing aircraft coincide with the center point of the connection portion. The first supporting member is equipped with an adjustment mechanism for vertically downwardly extending the length of the first supporting member.
US11325695B2 Rotor blade internal structure for trailing edge actuation
A rotor blade of a rotary wing aircraft includes a core defining a trailing edge of the rotor blade and a skin extending from the trailing edge defining an opening including the core. The skin defines an aerodynamic surface of the rotor blade. The rotor blade additionally includes at least one trim tab assembly including a trim portion extending from the core beyond the trailing edge of the rotor blade and an actuation system including at least one actuator disposed within the core. The actuation system is operable to adjust an angle of the trim portion relative to the rotor blade.
US11325693B2 Actuation unit for actuating a foldable wing tip portion of a wing for an aircraft
An actuation unit (15) for actuating a foldable wing tip portion (9) includes a first housing part (19) including a first attachment device (23) configured for attachment to a fixed wing (5), and a second housing part (21) including a second attachment device (25) configured for attachment to a foldable wing tip portion (9). The second housing part (21) is rotatable about a main axis of rotation (35). The second housing part (21) includes a toothed rack (37) having a concave shape and facing the main axis of rotation (35). A drive pinion (39) is supported at the first housing part (19) and engaging the toothed rack (37) for driving the second housing part (21) rotatingly relative to the first housing part (19). The drive pinion (39) is driven by a coupling arrangement (43) that is configured to be coupled to an output (45) of a motor unit (47).
US11325692B1 Propeller folding apparatus of air mobility vehicle
A propeller folding apparatus of an air mobility vehicle deploys or folds propeller blades depending on the flying state of the air mobility vehicle. The propeller blades are efficiently used depending on the flying state of the air mobility vehicle. The energy efficiency and the ferry range of the air mobility vehicle are increased.
US11325684B2 Inflatable kayak
The present disclosure provides an inflatable kayak. The inflatable kayak includes an inflatable floor having two ends defined upward; two inflatable gunwales arranged on the left and right sides of the inflatable floor, the height of the upper edge at both ends of the inflatable gunwale being higher than the height at the middle of the inflatable gunwale, allowing the height of the prow and the stern of the inflatable kayak to be no less than the height at the middle of the inflatable kayak; and a reinforcing assembly including a bottom reinforcing layer, a prow hatchway cover, and a stern hatchway cover, the bottom reinforcing layer at least covering the joints of the inflatable floor and the two inflatable gunwales. The prow hatchway cover connects the two inflatable gunwales at the prow, and the stern hatchway cover connects the two inflatable gunwales at the stern.
US11325683B2 Urinal for a boat
A urinal for a boat includes an outer shell that has an enlarged opening for accepting liquids (e.g. urine) and a drain. The drain is interfaced to an opening on a bottom surface of the outer shell for draining the liquids away from the boat. In some embodiments, there is a support unit for installing the urinal into an orifice (e.g. fishing pole holder) of the boat.
US11325681B2 Flood protection
An apparatus, system, and method are disclosed for a collapsible enclosure and a flotation container coupled to the collapsible enclosure to provide a buoyance to the collapsible enclosure. The collapsible enclosure comprises a floor portion, a top portion, and a side portion. The top portion is disposed opposite the floor portion. The side portion extends between the floor portion and the top portion. The collapsible enclosure being sealable to resist fluid penetration.
US11325680B2 Adjustable buoyancy foil
A foil for a towed cable includes a body defining at least two conduits. The body has a foil shape having a leading edge and a trailing edge. The foil shape defines a first surface extending between the leading edge and the trailing edge configured to provide lift. The foil shape defines a second surface opposed to the first surface extending between the leading edge and the trailing edge. The foil shape defines first and second lateral sides that extend between respective lateral edges of the first and second surfaces, the leading edge, and the trailing edge. A first conduit is defined within the forward half of the body adjacent to the leading edge, is open to each of the first and second lateral sides, and is configured to receive a cable therethrough. A second conduit may be defined within the body and filled with buoyant material.
US11325679B2 Boat hull with mounting track systems
A boat hull has one or more track systems integral with a main body of the boat hull, each track system having a longitudinally extending channel comprising: a longitudinally extending channel body; and a longitudinally extending channel opening in communication with the channel body, wherein the channel body is wider in cross-section than the channel opening, the channel body is adapted to receive a fastener which has a portion that is wider in cross section than the channel opening, thereby preventing the fastener from being withdrawn from the channel body through the channel opening, and wherein the fastener can be selectively secured to the track system at a selected longitudinal position. The track systems can be used for mounting boat hull structural parts and other parts and accessories.
US11325677B2 Bicycle propulsion system for electric bicycle conversion
A bicycle propulsion system including a concentric rotor assembly and a chassis assembly. The concentric rotor assembly: defines an outer drive surface; defines an inner retention surface; includes a set of sprocket brackets arranged about the inner retention surface of the concentric rotor assembly and configured to engage with teeth of a bicycle sprocket; and is configured to engage around the bicycle sprocket, wherein a center axis of the outer drive surface is concentric with a rotational axis of the bicycle sprocket. The chassis assembly: is configured to secure to a stay of the bicycle; includes a retention subassembly configured to translationally constrain the concentric rotor assembly relative to the chassis assembly; includes a drive subassembly configured to engage the outer drive surface of the concentric rotor assembly; and includes a motor configured to rotate the concentric rotor assembly via the drive subassembly.
US11325670B2 Saddle riding vehicle
A saddle riding vehicle includes a front fork including a pair of left and right fork tubes and a pair of top and bottom bridges connecting the left and right fork tubes, a headlight, and an electric part accommodating member accommodating electric parts, the electric part accommodating member being disposed on the rear side of the headlight in a space surrounded by the left and right fork tubes and the top and bottom bridges. The electric part accommodating member includes a fastening section fixed to the front fork by a fastening member and a fitting section fitted and fixed to the bridge.
US11325668B2 Adjustable shock-absorbing seat tube
The invention relates to a shock-absorbing seat tube, including an outer tube and an inner tube sleeved within the outer tube. The inner tube is adapted for connection to a bicycle saddle from below through a joint. The seat tube is provided with a height adjustment device having a supporting end inserted into the inner tube, and a shock-absorbing device disposed in the inner tube at a position above the height adjustment device and includes a fixing part and a damper part. The fixing part passes at its top end through the inwardly protruded portion of the inner tube and is arranged in the barrel portion of the inner tube. The damper part is arranged between the inwardly protruded portion and the supporting end.
US11325666B2 Vehicle and method for manufacturing vehicle body
A method for manufacturing an aluminum alloy vehicle body includes the following steps: vehicle body part molding, including: profile stretch-bending and machining; vehicle body frame assembly welding, including: performing assembly welding on a lower vehicle body, left and right side panels, and front and rear roof crossbeams; outer panel manufacturing, including: manufacturing an outer panel by injection molding; and whole vehicle assembling, including: assembling interior trim parts and the outer panel to a vehicle body frame, and assembling chassis parts to the vehicle body frame. The vehicle body parts and the vehicle body frame are made of an aluminum alloy material, and the outer panel is made of a non-metallic composite material.
US11325664B2 Reconfigurable bed rack system and method
A reconfigurable bed rack system and methods of manufacture and use that is dynamic, adaptable, lightweight, and easy to install are provided. The bed rack system may include a plurality of U-shaped modular telescoping support structures that allow for a height adjustment to the rack without uninstalling the rack from the truck bed. Through the telescoping feature of the U-shaped support structures, a height dimension of the bed rack system may be increased or decreased. One or more side and/or upper rails may extend between the plurality of U-shaped modular telescoping supports for attaching one or more mounting brackets to secure equipment, tools and/or supplies to the bed rack system. The rack system may also include a tire hoist bracket assembly including a hoisting system to store a spare tire against an upper, inner surface of the rack system.
US11325660B2 Safety support apparatus
Embodiments of the present invention provide a safety support apparatus for a cabin over engine (COE) truck cabin elevated in a raised position. The safety support apparatus provides a base member having a clamp mechanism which adjusts to truck chassis designs with rails of varying thicknesses. The frame of the safety support apparatus provides a receiver which may engage the bottom of an elevated truck cabin. The frame and base member are adjustable to allow configuration on either side of a truck cabin and deployment of the support apparatus at a range of angles.
US11325656B2 Drainage system for a vehicle
A drainage system for a vehicle is disclosed herein. A drain is disposed within a vehicle substrate and has a floor. A receiver is disposed proximate to the floor. A cap feature is operably coupled to the drain and is operable between first and second positions relative to the drain. The cap feature includes an upper platform and a sidewall that extends generally downward from the upper platform. A cutout is defined by the cap feature and is configured to allow liquid to flow through the cap feature. An engagement feature is coupled to the cap feature and is operable between a disengaged position and an engaged position in which the engagement feature is engaged with the receiver. Movement of the cap feature from the first position to the second position moves the engagement feature from the disengaged position to the engaged position.
US11325655B2 Body structure of eco-friendly vehicle for supporting battery
The present disclosure is to provide a body structure of an eco-friendly vehicle for supporting a battery including an intermediate floor panel composed of a first intermediate floor panel connected to a center floor panel and a second intermediate floor panel connected to a rear floor panel; a rear cross reinforcement panel and an extension reinforcement member mounted on a bottom portion in a battery seating area of the intermediate floor panel; and an intermediate floor upper panel mounted on a front portion in the battery seating area of the intermediate floor panel.
US11325649B2 Sleeve for repairing vehicle frame rail
This disclosure relates to a sleeve for repairing or reconstructing a frame rail of a motor vehicle. An exemplary repair sleeve includes a base wall, first and second side walls projecting from opposite sides of the base wall, and a sectioned wall including first and second sections spaced-apart from one another such that the two side walls are moveable relative to one another in a pre-installed condition.
US11325648B2 Front end module frame of vehicle
A front end module frame may include a cross member, a pair of side members extending from respective end portions of the cross member in a height direction of the vehicle, each of the pair of side members having a center portion connected to the front end portion of a corresponding one of front side members of the vehicle, an upper back beam member interconnecting the upper end portions of the pair of side members, the upper back beam member having opposite end portions respectively connected to the front end portions of upper fender apron members of the vehicle, and a lower back beam member extending in a width direction of the vehicle and interconnecting the center portions of the pair of side members.
US11325640B2 Apparatus and method for controlling motor driven power steering
An apparatus for controlling an motor-driven power steering (MDPS) may include: a driving information input unit configured to receive driving information; a steering angle position control unit configured to receive a command steering angle and a current motor steering angle of a driving motor, and output an autonomous driving command; and an MDPS control unit configured to drive the driving motor based on the autonomous driving command in an autonomous driving mode, determine whether a driver intervenes in steering, calculate a driver command by the driver's steering according to whether the driver intervenes in steering, and change an operation mode from the autonomous driving mode to a driver mode while driving the driving motor with a compensation output between the driver command and the autonomous driving command.
US11325639B2 Steering gear
A steering gear includes a gear wheel, a screw pinion meshing therewith, and a screw pinion shaft that includes the screw pinion. The screw pinion shaft is mounted on one side of the screw pinion in a fixed bearing. The steering gear includes a rotary bearing which comprises an inner bearing shell and an outer bearing shell. The outer bearing shell is connected to an inner ring of a swivel ring. The inner ring is connected to an outer ring of the swivel ring by a torsion web so as to pivot about a pivot axis. The torsion web runs at a distance from a supporting surface. The distance is dimensioned such that the torsion web does not contact the supporting surface when the screw pinion shaft is not loaded with a torque, and partially contacts the same when the screw pinion shaft is loaded with an operating torque.
US11325638B2 Dual-mode active rear-wheel steering device
A dual-mode active rear-wheel steering device, including: a steering motor, a main shaft, an intermediate gear, a transmission gear, a planetary gear coupling mechanism and a mode switching assembly. An output end of the steering motor is provided with a first input gear. An end of the main shaft drives a first rear wheel to rotate by a two-stage gear transmission system and a first rear-wheel motion conversion mechanism, and the other end of the main shaft drives a second rear wheel to rotate by the planetary gear coupling mechanism and a second rear-wheel motion conversion mechanism. The intermediate gear, the transmission gear and a sun gear of the planetary gear coupling mechanism are provided on the main shaft. The intermediate gear meshes with the first input gear.
US11325637B2 Steering system and method for manufacturing the same
A steering system includes a steering operation shaft, a lower shaft, an upper shaft, and an intermediate shaft. The intermediate shaft includes a tubular member including a hollow portion; and a shaft member. An oil groove that retains lubricating oil is provided in a predetermined range in an axial direction of the intermediate shaft on at least one of an outer peripheral surface of the shaft member at a part housed in the hollow portion and an inner peripheral surface of the hollow portion of the tubular member. A sectional area of the oil groove in an upper shaft-side part of the predetermined range is larger than a sectional area of the oil groove in a lower shaft-side part of the predetermined range, the upper shaft-side part being located on a side of the upper shaft, and the lower shaft-side part being located on a side of the lower shaft.
US11325634B1 Multifunction adaptive steering wheel control
A vehicle system comprising a steering wheel that includes: i) a hub adapted to be mounted on a steering column of the vehicle system; ii) a steering wheel rim coupled to the hub; and iii) a first control movably coupled to the hub. The first control moves from a first position proximate a first location on the steering wheel rim to a second position proximate a second location on the steering wheel rim. This maintains the first control in proximity to a first hand of a driver as the first hand moves from the first location to the second location on the steering wheel rim. The vehicle system further comprises a control module configured to move the first control from the first position to the second position.
US11325633B2 Passenger transport carriers
A child transport carrier includes a lower frame, an upper frame, a rear frame, and a first upper seat support. The lower frame includes a first end and a second end. The upper frame includes a first end and a second end. The rear frame extends from the second end of the lower frame to the second end of the upper frame. The first upper seat support includes a cross-member extending transversely across the first upper seat support and having a first end and a second end. The cross-member is configured to move the first upper seat support between a first seat position and a second seat position. The upper frame extends from an upper end of the rear frame and the lower frame extends from a lower end of the rear frame.
US11325631B2 Foldable frame assembly and stroller
A stroller and foldable frame assembly for a stroller includes a locking mechanism adjustable between a locked position and an unlocked position. The locking mechanism is configured to releasably lock the foldable frame assembly in its use configuration and/or storage configuration by releasably and internally locking at least one of a respective swivel joint assembly of the frame assembly. The locking mechanism includes an actuation element configured to adjust the locking mechanism between the unlocked and the locked position that is arranged spaced apart transversely to a swivel axis of the respective at least one internally lockable swivel joint.
US11325629B2 Transport trolley
The invention relates to a stackable transport trolley, in particular a stackable shopping trolley, comprising a chassis and a basket; the chassis includes a support frame and a frame of rods which is arranged on the support frame, the frame of rods supporting the basket.
US11325626B2 Stocking cart and method of transporting items using the same
A stocking cart includes a base structure having an opening configured to receive forks of a forklift; a plurality of wheels connected to the base structure; a back panel mounted to the base structure and extending opposite from the plurality of wheels; first and second lateral panels mounted to the base structure, the first and second lateral panels and the back panel defining an interior space of the cart; and at least one strap provided on an open side of the cart to provide access to the interior space of the cart, the at least one strap being configured to hold one or more items inside the cart. The cart also includes a linking mechanism configured to connect the cart to another cart.
US11325619B2 Universal public transport and utilities distribution system
The invention relates to a suspension bridge type self-supporting aerial metal structure, in which the main platform is designed having three levels. The upper level is intended for the passage of motor vehicles. The intermediate level is intended for the transportation, transmission and distribution of all existing public services, and other possible services. The lower level is intended for an urban public transport system. Thanks to its self-supported aerial design, the structure of the present invention can be built within cities following the same layout as existing roads.
US11325612B2 Passenger safety system
Disclosed is a passenger safety system for a vehicle that can remind a driver of the vehicle to check seats before leaving the vehicle. The system includes a control unit connected to an ignition sensor. The control unit can receive a signal from the ignition sensor indicating turning-off the ignition. The system may also include a weight sensor installed in the rear seat of the vehicle. The weight sensor is activated when an object is placed on the rear seat. The control unit can trigger an alert upon receiving a signal from the ignition sensor and the weight sensor is active. The alert can be an audio and/or visual alert for reminding the driver.
US11325610B2 Maintenance and repair system for advanced driver assistance features
A calibration and repair system for advanced driver assistance systems (“ADAS”) and features is configured to provide secure, automated workflow management related to the calibration of User Remote ADAS. Automated workflows include steps and interfaces to aid in preparation of a vehicle for calibration, local-remote collaboration during calibration, customer interactions, workflow and event notification, user authentication, remote system management, and other tasks. The system is also capable of automatically and dynamically adding new and updated calibration specifications that are usable during local-remote collaboration.
US11325609B2 Vehicle driving assist system
A vehicle driving assist system includes an imaging device, an alarm, and a controller. The controller includes a facial recognition unit, an occupant determination unit, and a loss determination unit. The facial recognition unit recognizes at least a part of an occupant's face in first captured images acquired from the imaging device. The occupant determination unit determines a driving state of the occupant on the basis of a second captured image in which at least the part of the face is recognizable, and generate a first alert request if the occupant is unable to drive the vehicle. The loss determination unit generates a second alert request if a third captured image in which at least the part of the face is unrecognizable occurs two or more times. The alarm outputs an alert to the occupant on the basis of the first and second alert requests.
US11325608B1 System and methods for determining owner's preferences based on vehicle owners telematics data
Embodiments described herein receive telematics data collected over a period of time, wherein the telematics data is indicative of operation of a vehicle by an owner of the vehicle during the period of time; analyze the telematics data to identify driving behavior(s) of the owner during the period of time; predict one or more user preference values of a vehicle-sharing platform profile of the owner based on the identified one or more driving behaviors, wherein the one or more user preference values define one or more criteria for vehicle renters with whom the first vehicle can be shared; apply the one or more criteria to a potential vehicle renter; and cause an indication of the first vehicle of the owner to be displayed via a mobile device of the potential renter only if the potential vehicle renter satisfies the one or more criteria.
US11325607B1 Systems and methods for analyzing telematics data to determine a driver on a shared trip
A design solution for classifying users as potential drivers traveling in a vehicle based upon a combination of real-time data gathered during a shared trip and historical data. Data gathered include overlapping time and distance of users to be classified as potential drivers. Shared trip scenarios include two or more users share a complete trip from beginning to end; two or more users share the beginning of a trip where at least one user is dropped off and the other user continues driving; two or more users share the end of a trip where at least one user is picked up during the shared trip; and one user picks up another user during a trip to thereby create a shared trip and drop off the other user to a different location before heading to a final location.
US11325599B2 Vehicle control system for adjusting longtitudinal motion to reduce deviation of lateral motion
A vehicle motion control system includes: a steering angle sensor for detecting a steering angle; a vehicle speed sensor for detecting a vehicle speed; a lateral acceleration sensor for detecting an actual lateral acceleration of a vehicle body; a reference lateral acceleration calculation unit configured to calculate a reference lateral acceleration from the steering angle and the vehicle speed; a required longitudinal force calculation unit configured to calculate a required longitudinal force for reducing a deviation of the actual lateral acceleration relative to the reference lateral acceleration; and a longitudinal force control unit configured to control an output of at least one of a brake and a power plant such that the required longitudinal force is generated.
US11325597B2 Calibration device for lane keeping assist system
The present invention relates to the technical field of automobile maintenance and discloses a calibration device for a lane keeping assist (LKA) system. The calibration device includes a support apparatus, a laser and a pattern board. The support apparatus includes a horizontal graduated scale. The laser is configured to be mounted on the body of an automobile and to emit a laser beam to the horizontal graduated scale. The pattern board is mounted on the support apparatus and is configured to attach an alignment pattern. By means of the calibration device, two lasers are mounted on wheels on two sides of the automobile. Two laser beams that are emitted from equal distances with the wheels being reference points are irradiated to the horizontal graduated scale. Based on marks on the horizontal graduated scale, the support apparatus may be moved to an appropriate position to calibrate the centerline of the automobile.
US11325591B2 System and method for teleoperation service for vehicle
A vehicle control system to provide driving assistance for a vehicle include a plurality of sensors and circuitry. The plurality of sensors captures one or more signals associated with the vehicle. The circuitry identifies a trigger input to change a current operation mode of the vehicle to a teleoperation mode of the vehicle. The circuitry further transmits, in the teleoperation mode, the captured one or more signals to a teleoperation server of a plurality of teleoperation servers. The circuitry further receives, in the teleoperation mode, one or more vehicular instructions from the teleoperation server based on the transmitted one or more signals. The circuitry further controls, in the teleoperation mode, at least one component of the vehicle based on the received one or more vehicular instructions to control movement of the vehicle.
US11325583B2 Hybrid vehicle and method of controlling hybrid vehicle
A vehicle includes: a motor generator; an engine having a forced induction device; and a HV-ECU. An operation region of the engine includes a PM generating region in which an amount of particulate matters included in exhaust gas of the engine is more than a predetermined amount due to a load of the engine being abruptly increased during boosting by the forced induction device. The PM generating region is a low-rotation and high-torque region. When assistance by the motor generator is sufficiently obtained and the engine is operated in the PM generating region, the HV-ECU restricts an increasing rate of the torque of the engine to be less than or equal to an upper limit rate. The HV-ECU complements, by the torque of the motor generator, the torque of the engine restricted by restricting the increasing rate of the torque of the engine.
US11325582B2 Vehicle control apparatus
A vehicle control apparatus includes a determination processor and a regeneration controller. During traveling in a first travel mode, the determination processor determines a timing at which a regenerative braking force based on a motor regenerative force is to be increased under the condition that an accelerator-off operation period is equal to or less than a predetermined period. During traveling in a second travel mode, the determination processor refrains from determining the timing at which the regenerative braking force is to be increased under the sole condition that the accelerator-off operation period is equal to or less than the predetermined period. The regeneration controller performs control that increases the motor regenerative force as the determination processor determines the timing at which the regenerative braking force is to be increased.
US11325581B2 Control system for hybrid vehicle
A control system for a hybrid vehicle configured to start an engine promptly during propulsion in an electric vehicle mode. Electric power generation resulting from cranking the engine by a first motor is greater in the first electric vehicle mode compared to a second electric vehicle mode. A controller that is configured to determines whether an acceptable input power to an electric storage unit is smaller than a threshold value. If the acceptable input power to the electric storage unit is smaller than the threshold value, selection of the first electric vehicle mode is inhibited.
US11325580B2 Hybrid vehicle transmission control using driver statistics
A multi-layer control mechanism for optimizing performance metrics of a hybrid electric vehicle (e.g., fuel efficiency, drivability, NVH). A first layer generates a policy that defines target engine & motor operating settings for each of a plurality of possible driver demand inputs based on a predicted driver demand profile for a long-horizon period of time. A second layer determines a predicted “short-horizon” driver demand—based, for example, on historical driver data and one or more environmental sensor inputs—and applies a corrective pre-adjustment to the operating settings of the vehicle in response to determining that a pre-adjustment is required in order to apply the target operating settings for the predicted driver demand. A third layer determines constraints to the operating settings required to comply with the additional performance parameters and limits the operating settings applied to the engine and motor(s) to feasible operating settings defined by the constraints.
US11325575B2 Brake valve, compressed-air brake system having the brake valve, and method for producing the brake valve
A brake valve for a compressed air brake system of a utility vehicle includes a compressed air input configured to connect to a system pressure, a compressed air output configured to connect a brake control line, and at least one sensor configured to determine a brake valve actuation travel of an actuating element of the brake valve with a working interconnection to the brake pedal. The brake valve further includes a characteristic curve memory storing two stored characteristic curves and/or dependences and at least one determination device. The brake valve is configured to output at least two useful sensor signals, a first of which represents a brake valve output pressure and a second of which represents a percentage actuation position of the actuating element. The at least one sensor is configured to generate an actuating signal depending on the brake valve actuation travel of the actuating element.
US11325573B2 Rear wheel regenerative braking control system for vehicle and method therefor
A rear wheel regenerative braking control system for vehicle, may include a brake controller; a vehicle controller; a hydraulic controller; and a motor controller, wherein the system and the method may maximize an amount of rear wheel regenerative braking while easily securing braking stability of a vehicle.
US11325569B2 Dump-truck fluid assistance system and method
A dump-truck fluid assistance system and method for prevention and remediation of material sticking to the truck bed and dampening generation of dust, at different stages of loading, transport, and dumping operations. Fluid is emitted from one or more outflow manifolds inside the bed of the dump truck for one or more purposes of lubricating the truck bed, regulating the temperature of the truck bed, physically flushing material from the truck bed, and dampening generation of airborne particles or dust. Under the control of a controller having a controller transceiver, directed via a cab operator transceiver or remote operator transceiver, a fluid pump sends fluid from a fluid reservoir via a fluid line into the outflow manifolds that emit the flow of fluid variously as spray, stream, jet, drip, or weep, into the bed of the dump truck.
US11325568B2 Wiper blade device
The invention relates to a wiper blade device, in particular a windscreen wiper blade device, comprising: at least one wiper blade (10); at least one adapter unit (12) for coupling the wiper blade (10) to a wiper arm (14) of a wiper (16), in particular a windscreen wiper; at least one spraying unit (18) integrated in the wiper blade (10); and at least one washing water distributor unit (20) for supplying washing water to the spraying unit (18), in particular to nozzle elements (22) of the spraying unit (18) which are arranged substantially parallel to a main extension direction (54) of the wiper blade (10) along the wiper blade (10), wherein the washing water distributor unit (20) has at least one channel coupling element (24) for coupling at least one portion of the washing water distributor unit (20) to a washing water channel (26) of the spraying unit (18), the coupling being provided in particular for passage of a fluid and being preferably fluid-tight, and wherein the washing water distributor unit (20) has at least one adapter coupling element (28) for coupling at least one additional portion of the washing water distributor unit (20) to an additional washing water channel (30) of the adapter unit (12), the coupling being provided in particular for passage of a fluid and being preferably fluid-tight. According to the invention, the additional washing water channel (30) is formed at least in part by the adapter unit (12).
US11325567B2 Windscreen wiper arm, particularly for automobiles
A windscreen wiper arm, particularly for automobiles, that is able to oscillate upwardly and downwardly between a downward position and an upward position. One end of the windscreen wiper arm is adapted to be pivotally connected to a mounting head mounted on a drive shaft. Another end of the windscreen wiper arm is rigidly connected to an adapter adapted to be connected to an elongated wiper blade to be placed in abutment with a windscreen to be wiped. A joint part is adapted to be interposed between the adapter and the elongated wiper blade. The adapter, at the location of its connection to the wiper blade, has a U-shaped cross-section with a base and two spaced-apart legs. The windscreen wiper arm is provided with a nozzle for spraying a washing liquid onto the windscreen to be wiped. The nozzle is detachably connected to the adapter. At least one protrusion of the nozzle engages into a corresponding hole in one of the legs of the U-shaped cross-section of the adapter. The protrusion extends inwardly in a direction towards the adapter. The protrusion has a shank passing through the hole, and an enlarged head abutting an inner wall of the leg provided with the hole. The joint part is provided with a slit in which the enlarged head rests for blocking any movement of the protrusion in a direction towards the windscreen to be wiped and in a direction away from the windscreen to be wiped.
US11325565B2 Vehicle recognition device and vehicle control apparatus
A vehicle recognition device includes a vehicle recognizer and a wiper controller. The vehicle recognizer is configured to determine, upon a first state, whether a transition is made from the first state to a second state. The first state is a state in which a second vehicle is recognizable from captured images obtained from respective cameras provided in a first vehicle. The second state is a state in which the second vehicle is unrecognizable from one or more of the captured images. The one or more of the captured images is obtained from all or a part of the cameras. The wiper controller is configured to automatically control an operation of a wiper of the first vehicle on the basis of an automatic control, when the vehicle recognizer determines that the transition is made from the first state to the second state.
US11325564B2 Vehicular illumination system with reconfigurable display element
A vehicular illumination system includes a ground illumination module disposed at a side door of a vehicle. The ground illumination module includes a reconfigurable display element and at least one light source operable to emit light. When the at least one light source is electrically powered, light emitted by the at least one light source illuminates a ground region adjacent the vehicle. When the at least one light source is electrically powered, light emitted by the at least one light source passes through the reconfigurable display element and the ground illumination module projects an icon established by the reconfigurable display element onto the ground region. The reconfigurable display element is reconfigurable to form the icon responsive to programming of the reconfigurable display element for an icon.
US11325562B1 Wire management module for a vehicle
A wire-management module is configured to be installable to a vehicle having an operable system configured to be energized in response to operative connection between a first wire and a second wire. A user-authentication module is configured to transmit a wire-management signal including a wire-inhibit signal configured to indicate lack of authorization to use the operable system of the vehicle. The wire-management module is configured to be operatively coupled to the first wire and the second wire. The wire-management module has a signal input port configured to receive the wire-inhibit signal that is transmittable from the user-authentication module. The wire-management module is also configured to inhibit operative connection between the first wire and the second wire.
US11325560B2 Attention calling device and attention calling system
An attention calling device is configured to call attention of a driver of a vehicle with a drive mode switchable among manual driving, drive assist, and driver-centered automated driving. The attention calling device includes: a drive mode recognition unit configured to recognize the drive mode being executed; a driver state recognition unit configured to recognize a driver state based on a captured image from a driver monitor camera provided in the vehicle; a determination unit configured to determine based on the driver state whether it is necessary to call the attention; and a control unit configured to control a stimulus application device of the vehicle so as to apply a stimulus at an intensity that matches the drive mode being executed to the driver to direct the attention of the driver to driving of the vehicle when the determination unit determines that it is necessary to call the attention.
US11325556B2 Vehicle airbag
A vehicle includes a bulkhead. The vehicle includes an airbag supported by the bulkhead and inflatable to an inflated position. The airbag in the inflated position includes a main chamber and a pair of side chambers that extend transversely from the main chamber. The vehicle includes a seat having a seatback and a seat bottom that extends from the seatback in a direction away from the bulkhead. The seatback is between the side chambers in the inflated position.
US11325553B2 Side airbag device
A side airbag device capable of preventing interference between a harness and an airbag is provided between a vehicle body and a seat. The side airbag device includes an airbag module including an inflatable airbag and an inflator supplying a gas into the airbag, a base member including an airbag storage portion having a concave shape and storing the airbag module and is attached between a vehicle body door and the seat, and a retainer member holding the airbag storage portion from the rear side of the vehicle body. The base member includes a first through hole through which a harness of the inflator is inserted and a flange which is formed in the periphery of the first through hole. The retainer member includes a second through hole through which the harness of the inflator is inserted and which is provided at a position facing the first through hole.
US11325546B2 Rotary connector
A rotary connector includes a case including a housing space and fixed to a vehicle body that includes a steering wheel including a steering-side electric component, a rotor that is rotatable around a rotational axis relative to the case, a first connector provided on the rotor and electrically connected to the steering-side electric component, a second connector provided on the case and electrically connected to a vehicle-side electric component in the vehicle body, a flexible cable that is provided in a wound state in the housing space of the case and electrically connects the first connector to the second connector, and a controller that is disposed between the first connector and the flexible cable and performs a predetermined process on an electric signal transmitted between the first connector and the flexible cable. The controller is configured to rotate together with the rotor.
US11325539B2 Fishing gear carrier box
A cargo box for securely carrying fishing rods and related cargo on top of a vehicle is disclosed, including a top portion hingedly connected to a bottom portion. The bottom portion includes plurality of rod holder assemblies to support and securely hold plurality of fishing rods and reels during transport between locations. The rod holder assemblies are configured to be repositionable to accommodate various lengths of fishing rods.
US11325536B2 Vehicle exterior system with light module
A lighted exterior mirror system suitable for use in a vehicle includes a lighted exterior rearview mirror assembly having a light module, which includes a planar circuit board and a light guiding element. The light module includes a plurality of illumination sources disposed on a mounting side of the circuit board and operable to emit light. When the illumination sources are actuated, light emitted by each of the illumination sources is emitted in a direction normal to the mounting side of the planar circuit board. The light guiding element is configured so that light emitted by the illumination sources is redirected by the light guiding element so that light emanates from the light guiding element in a direction parallel to the mounting side of the planar circuit board and parallel to the road surface.
US11325533B2 Frameless interior rearview mirror assembly
A vehicular interior rearview mirror assembly includes a mounting portion, a mirror casing and a mirror reflective element. The reflective element includes a glass substrate having a planar front surface, a planar rear surface and a circumferential perimeter edge around a periphery of the glass substrate that extends across a thickness dimension separating the planar front surface from the planar rear surface. A front perimeter edge portion of the circumferential perimeter edge includes a rounded glass surface circumferentially around the periphery of the glass substrate, with the rounded glass surface at least partially spanning the thickness dimension of the glass substrate. The rounded glass surface has a radius of curvature of at least 2.5 mm. The planar rear surface of the glass substrate is coated with a coating. No portion of the mirror casing overlaps onto the rounded glass surface of the glass substrate.
US11325524B2 Collaborative vehicle headlight directing
Various embodiments include methods and vehicles, such as an autonomous vehicle, a semi-autonomous vehicle, etc., for collaboratively directing one or more headlights by two or more vehicles. Various aspects may include receiving, by a first vehicle processor, a first vehicle collaborative lighting message from a second vehicle, in which the first vehicle collaborative lighting message requests that the first vehicle direct one or more headlights of the first vehicle to illuminate a target area of uncertainty that is disposed, relative to the first vehicle, in a direction other than a direction of travel of the first vehicle. The first vehicle processor may direct one or more the headlights of the first vehicle to illuminate the target area in accordance with the first vehicle collaborative lighting message.
US11325522B2 Automatic light system
An automatic light system is provided for automatically turning on and off vehicle lights in accordance with the surrounding environment. The system includes an imaging device that images an area in front of the vehicle and generates image data; an image processing unit that generates light mode information on the basis of the brightness in an upper region and lower region of the image data; and a light control unit that controls the lights on the basis of the light mode information. The image processing unit sets a higher weight to a measurement region in the movement direction of the vehicle from among a plurality of measurement regions set in the upper region and a lower weight to the other measurement regions to calculate the brightness in the upper region and generates the light mode information on the basis of the brightness in the upper region.
US11325517B2 Tailgate apparatus for dump trucks and dump trailers
A tailgate apparatus for a dump body is described herein. The dump body includes a floor, a front wall coupled to and extending upwardly from the floor and two opposing side walls coupled to and extending upwardly from the floor. Each side wall is coupled to the front wall. The two side walls define an opening at a rear end of the floor. The tailgate apparatus includes a tailgate sized to cover the opening and two opposed side arms extending from the tailgate towards the front wall. Each side arm is pivotally coupled to a respective one of the side walls. The tailgate apparatus also includes a pair of linkages for linking the side arms to the side walls. The linkages enable the tailgate to pivot between a closed position where the tailgate covers the opening and an open position where the tailgate is positioned closer to the front wall than the opening.
US11325516B2 Storage device for a vehicle
A storage device for a vehicle includes a housing, a drawer which can be moved relative to the housing along a vehicle longitudinal direction between a closed state and an open state when used as intended, and a plate which is mounted by way of a bearing device attached to the drawer such that the plate can be pivoted about a pivot axis extending along a vehicle transverse direction.
US11325514B2 Armrest
An armrest includes a bracket fixed to a frame of a seat, an armrest body member rotatably mounted on the bracket, a receiver coil mounted in the armrest body member, and a transmitter coil mounted in the bracket and transferring power to the receiver coil with a non-contact transmission system.
US11325513B2 Seat device for vehicle
A seat device for a vehicle includes a seat cushion, a slow deformation portion, and tilted standing members. An occupant in the vehicle is to be seated on the seat cushion. The deformation portion is disposed in at least a portion of the seat cushion and configured in such a manner that the deformation portion is deformed as a result of a load to be applied continuously to the deformation portion. The standing members stand in a load direction in an inner portion of the deformation portion and configured to be tilted as a result of the deformation of the deformation portion. When the outer and inner portions of the deformation portion are deformed by the load, the standing members in the outer and inner portions and the standing members in the inner portion are tilted respectively forward and rearward, from their respective positions before the load is applied.
US11325506B2 Brake device for motor vehicle seat
A brake device for a motor vehicle seat is composed of a brake assembly, a tooth assembly, and a lever assembly. The brake assembly includes a housing, a pinion shaft, a braking component, and a drive wheel that are structured to be self-held in an assembled state by mechanical interaction thereamong. The tooth assembly includes a holder plate and a tooth plate that are structured to be self-held in an assembled state by mechanical interaction therebetween. The lever assembly includes an input lever, a cover, a coil spring, and a lever bracket that are structured to be self-held in an assembled state by mechanical interaction thereamong. The brake assembly, the tooth assembly, and the lever assembly are arranged and assembled together in an axial direction.
US11325504B2 Track for seat
The present disclosure relates to a track for an automotive vehicle seat comprising: a first, upper, rail and a second, lower, rail mounted sliding relative to each other along a sliding axis, that define a cavity between them; a bolt comprising at least one locking member movable from a locked position in which the at least one locking member immobilizes the first rail and the second rail relative to each other, and an unlocked position and a guiding system for the at least one locking member between the first locked position and the second unlocked position, secured to the first, upper, rail, where the guiding system comprises an inner guide secured to the first rail at two anchoring points extending respectively the guide forming body above and below a guiding orifice.
US11325502B2 Electric vehicle
An electric vehicle includes first to fourth motors respectively mounted to individually rotate right and left wheels in the front and rear of the vehicle, first to fourth fuel cell stack modules independently connected to the respective motors so as to supply power to the first to fourth motors, a battery pack for supplying power to the first to fourth motors, a main control part for controlling the first to fourth motors, the first to fourth fuel cell stack modules and the battery pack and a tank for supplying hydrogen gas to the first to fourth fuel cell stack modules.
US11325501B2 Method for preheating a battery of an electrically operated motor vehicle, and charging device
A method for preheating a battery of an electrically driven motor vehicle, in particular an electric vehicle or a hybrid vehicle, controls a charging process and a discharging process of the battery in such a way that a minimum temperature of the battery is attained at a departure time of the motor vehicle.
US11325500B2 On-board electrical network for a motor vehicle
The invention relates to a method for operating an on-board electrical network (4) of a motor vehicle (2), with a first voltage circuit (I) and a second voltage circuit (II), the first voltage circuit (I) having a first operating voltage which is higher than a second operating voltage in the second voltage circuit (II), the first voltage circuit (I) being connected to the second voltage circuit (II) via a DC-DC converter (8), and the first voltage circuit (I) having a battery (10) and the second voltage circuit (II) having a main battery (12), characterized in that the second voltage circuit (II) has an additional third auxiliary battery (14), and wherein by means of a changeover switch assembly (18) components of the motor vehicle (2) are supplied with electrical energy from the main battery (12) and/or the auxiliary battery (14), and in that the main battery (12) is disconnected from the second voltage circuit (II) by means of an isolating switch (66) during a startup mode.
US11325499B2 Multi-battery system for an electric vehicle
A multi-battery system includes a plurality of batteries, a first connector having a first identification unit, and a second connector having a second identification unit. Each battery includes a microcontroller, and a battery connector having a detection unit. The first connector is for electrically connecting a battery connector of a first battery of the plurality of batteries and a motor controller. The second connector is for electrically connecting a battery connector of a second battery of the plurality of batteries and the motor controller. When the first identification unit is set to a first predetermined value, and a detection unit of the first battery is electrically connected to the first identification unit, a microcontroller of the first battery sets the first battery as a master battery.
US11325498B2 Vehicle energy management system and related methods
A through the road (TTR) hybridization strategy is proposed to facilitate introduction of hybrid electric vehicle technology in a significant portion of current and expected trucking fleets. In some cases, the technologies can be retrofitted onto an existing vehicle (e.g., a truck, a tractor unit, a trailer, a tractor-trailer configuration, at a tandem, etc.). In some cases, the technologies can be built into new vehicles. In some cases, one vehicle may be built or retrofitted to operate in tandem with another and provide the hybridization benefits contemplated herein. By supplementing motive forces delivered through a primary drivetrain and fuel-fed engine with supplemental torque delivered at one or more electrically-powered drive axles, improvements in overall fuel efficiency and performance may be delivered, typically without significant redesign of existing components and systems that have been proven in the trucking industry.
US11325492B2 Method for determining optimal placement of electric vehicle chargers
A method for the efficient placement of electric vehicle chargers in a target area couples vehicle dynamics and battery dynamics modeling with environmental factors to accurately incorporate the impact that the environment has on the range of the battery into the placement of the chargers by simulating trips of fleets of electric vehicles. The vehicles can be of various types, for example, motorcycles, cars, trucks or aircraft, and will each have their battery state of charge monitored as they traverse a simulated trip through the target area.
US11325491B1 Charging station with passive alignment mechanism
A charging station for an electric vehicle includes a passive alignment mechanism that includes a longitudinal translation stage that allows motion in a longitudinal direction, a charging plug connected to the passive alignment mechanism, and a releasable connector. The releasable connector resists motion of the longitudinal translation stage in a connected position when a magnitude of an external force applied in the longitudinal direction is below a threshold. The releasable connector moves from the connected position to a released position to allow motion of the longitudinal translation stage when the magnitude of the external force applied in the longitudinal direction is above the threshold.
US11325488B2 Housing for a charging device for a vehicle
A housing for an electrical connector includes a first set of orifices receiving a plurality of first pins, a second set of orifices receiving a plurality of second pins, a first draining device evacuating a fluid from the first set of orifices, and a second draining device evacuating a fluid from the second set of orifices. The second pins having a voltage higher than the first pins. The first set of orifices and the second set of orifices extend through the housing from a first interface of the housing toward a second interface of the housing in a connecting direction. The first draining device and the second draining device are isolated from each other and prevent fluid communication between the fluid from the first set of orifices and the fluid from the second set of orifices.
US11325483B2 Plate and plate system
A plate is to be installed on an installation surface for supporting an object to be supported on the installation surface. The plate includes a plate part having a support surface for supporting the object to be supported, and an adjustment part attached to the plate part and capable of adjusting a height position of the support surface relative to the installation surface.
US11325479B2 Hybrid and electric vehicle battery maintenance device
The present invention includes a battery pack maintenance device for performing maintenance on battery packs of hybrid and/or electrical vehicles (referred herein generally as electric vehicles). In various embodiments, the device includes one or more loads for connecting to a battery pack for use in discharging the battery pack, and/or charging circuitry for use in charging the battery pack. Optional input/output circuitry can be provided for communicating with circuitry of in the battery pack and/or circuitry of the vehicle.
US11325474B2 Electrical machine for driving propulsion
The invention relates to a particularly redundant electrical machine (10) for driving a means of propulsion (1) with increased reliability. The machine (10) comprises a plurality of independent partial rotors (210, 220) which are respectively coupled to a common shaft (200) by means of freewheel devices (510, 520) in order to drive said shaft and the means of propulsion (1) therewith in a working direction of rotation. The machine (10) also comprises a plurality of independent stator winding systems (111, 121), a stator winding system (111, 121) and a partial rotor (210, 220) being respectively associated with each other and arranged in such a way that they can electromagnetically interact with each other. The stator winding systems (111, 121) are successively arranged in the axial direction. Similarly, the partial rotors (210, 220) are successively arranged in the axial direction.
US11325468B2 Vehicle power management system
An apparatus comprising an interface, a memory and a processor. The interface may be configured to receive sensor data samples during operation of a vehicle. The memory may be configured to store the sensor data samples over a number of points in time. The processor may be configured to analyze the sensor data samples stored in the memory to detect a pattern. The processor may be configured to manage an application of brakes of the vehicle in response to the pattern.
US11325467B2 Gear transmission
A gear transmission having a speed changing section includes a speed changing gear for setting a speed stage and a shift gear slidably mounted on a rotation support shaft and operated to engage and disengage with the speed changing gear, the speed changing section configured to speed-change inputted power and to output the resultant power via the rotation support shaft. An arrangement is provided for facilitating engagement of the shift gear with the speed changing gear even when respective end faces of the shift gear and the speed changing gear hit each other. A transmission mechanism (20B) is provided for outputting power of a rotation support shaft (24) to a traveling device. The transmission mechanism (20B) has a transmission flexibility portion (80) which allows free rotation of the rotation support shaft (24) by a set rotation angle.
US11325464B2 Method for producing a liquid container, liquid container for a motor vehicle, and structure for reducing sloshing sounds
The invention relates to a method for producing a liquid container for a motor vehicle, having the method steps: providing a wall, which is provided in order to delimit an interior chamber of the liquid container for receiving a liquid; providing a structure, which is provided in order to be arranged in order to reduce sloshing noises in the interior chamber of the liquid container, wherein the structure comprises a random arrangement of threads cross-linked with each other and wherein a plurality of the threads of the structure are integrally joined, at least in sections, to at least one or more additional threads of the structure, such that a substantially monolithic structure is formed; connecting the structure to the wall.
US11325456B2 Clutch assembly with vibration dampers and vehicle drive train
Various embodiments may include a clutch assembly comprising: a first coupling and a second coupling; and a vibration damper with a spring. The first coupling includes a crankshaft connection and a coupling-in element which can be connected to one another in a controlled manner. The second coupling has an output connection and an intermediate element which can be connected to one another in a controlled manner. The spring connects the intermediate element and the coupling-in element to one another.
US11325446B2 Method for operating a refrigeration system for a vehicle and a corresponding refrigeration system
A method for operating a refrigeration system for a vehicle with a refrigerant circuit including a heat exchanger. A controllable environmental air flow (L) is flowed through the heat exchanger and the heat exchanger can be operated as a refrigerant condenser or a gas cooler for a refrigeration system operation.
US11325445B2 Thermal management system for vehicle
A vehicle thermal management system includes a cooling apparatus including a radiator, a first water pump, and a valve connected through a coolant line, a battery cooling apparatus including a second water pump and a battery module connected by a battery coolant line; a chiller connected to the battery coolant line and connected to an air conditioner through a refrigerant connection line connected to the battery coolant line and connected to a refrigerant line of the air conditioner through a refrigerant connection line, to adjust a temperature of the coolant by performing heat exchange between a coolant supplied to the battery coolant line and a refrigerant selectively supplied from the air conditioner; and a heating circuit for warming an interior of the vehicle by use of the coolant having a temperature increased while the coolant passes through at least one electrical component.
US11325443B2 Heat pump system for vehicle
A heat pump system for a vehicle utilizes one chiller in which a coolant and a refrigerant are heat-exchanged to adjust a temperature of a battery module, and utilizes a sub-centralized energy module with waste heat of an electrical component in a heating mode of the vehicle to improve heating efficiency.
US11325441B2 Seat air conditioner
The seat air conditioner configured to supply conditioning air to a seat in a vehicle cabin includes a refrigeration cycle, an air blower, and a conditioning air supply unit. The refrigeration cycle includes a compressor that compresses and discharges a refrigerant, a heat emitting portion that emits heat of the refrigerant discharged from the compressor to generate a warm air, a decompressor that decompresses the refrigerant flowing out of the heat emitting portion, and a heat absorbing portion that evaporates the refrigerant decompressed by the decompressor to generate a cold air. The air blower blows air to exchange heat with the refrigerant. The conditioning air supply unit supplies each of the warm air generated by the heat emitting portion and the cold air generated by the heat absorbing portion as the conditioning air to the seat.
US11325438B2 Suspension
A suspension is provided which can not only generate a damping force between sprung mass and unsprung mass but also steer a wheel. A suspension includes: a shaft coupled to sprung mass of a vehicle, the shaft having a screw groove and a spline groove formed thereon; a ball screw nut assembled to the shaft via a ball; a ball spline nut assembled to the shaft via a ball; a ball screw-specific motor connected to the ball screw nut; a ball spline-specific motor connected to the ball spline nut; and a case coupled to unsprung mass of the vehicle, the case being configured to hold the ball screw-specific motor and the ball spline-specific motor. The ball spline-specific motor rotates the ball spline nut and the shaft relative to the case.
US11325431B2 Wheel hub mounted vehicle data communications device incorporating a self-generating electrical power supply
A wireless vehicle data communications device is adapted for mounting on a wheel hub assembly of a vehicle. The vehicle data communications device includes a housing, a microprocessor located inside the housing, a signal transmitting device, and a signal receiving device. A self-generating electrical power supply is located within the housing and functions to supply electrical power to components of the vehicle data communications device.
US11325425B2 Tyre for a motorcycle for rough terrain
A tyre for a motorcycle for rough terrain comprises a tread portion. In a region between at least one of tread edges and a tyre equator, the tread portion is provided with middle blocks, shoulder blocks, and tie bars each connecting between one of the middle blocks and its adjacent one of the shoulder blocks. The shoulder blocks include first shoulder blocks forming the one of the tread edges and second shoulder blocks arranged on an inner side in a tyre axial direction of the one of the tread edges. The tie bars include first tie bars each connecting between one of the middle blocks and one of the first shoulder blocks and second tie bars each connecting between one of the middle blocks and one of the second shoulder blocks.
US11325423B2 Pneumatic tire and pneumatic tire manufacturing method
A pneumatic tire includes a tread portion with shoulder lug grooves spaced apart in a circumferential direction, each extending outward in a tire lateral direction, opening to a ground contact end, and including a closed end inward in the tire lateral direction. In a region of each of the shoulder lug grooves from an end of a belt having a greatest width in a belt portion of the pneumatic tire to an inner side in the tire lateral direction, the shoulder lug groove has a groove width that decreases inward in the tire lateral direction, and includes a portion where a groove cross-sectional area is kept constant by a change in at least one of a groove wall angle or a groove depth of the shoulder lug groove, the portion being provided in the tire lateral direction across a length of at least 20% of half a tire development width.
US11325417B2 Wheel assembly including arcuate inner and outer rim assemblies and related methods
A wheel assembly to be coupled to a hub of a vehicle, may include arcuate inner rim assemblies removably coupled together to define a circular inner rim to be coupled to the hub of the vehicle. Each arcuate inner rim assembly may include an arcuate inner rim segment, and an arcuate inner ring segment extending radially outward from the arcuate inner rim segment. The wheel assembly may also include arcuate outer rim assemblies removably coupled together to define a circular outer rim. Each arcuate outer rim assembly may include an arcuate outer rim segment, and an arcuate outer ring segment extending radially inward from the arcuate outer rim segment. The wheel assembly may also include gas springs operatively coupled between the circular inner rim and the circular outer rim to provide a gas suspension for relative movement therebetween.
US11325412B2 Security element comprising micro-reflectors for a perspective representation of a motif
A flat security element with microreflectors arranged as a microreflector pattern in a main plane of the security element. The microreflectors present a motif made up of image points to a viewer. The motif appears for the viewer as lying outside the main plane of the security element. Two of the microreflectors are adjusted in each case to produce one of the image points of the motif appearing for the viewer as lying outside the main plane. The microreflector pattern has several groups of microreflectors. Each of the groups is provided to represent to the viewer a perspective view of the motif after tilting the security element about an axis lying in the main plane. Image points of the motif are shifted by shift ranges of different sizes through the tilting.
US11325411B2 Printing blanket and method for manufacturing printing blanket
A method for manufacturing a printing blanket including an elastic body that can be repeatedly used by removing a sheet is provided. According to the above of the present invention, the printing blanket includes an elastic body and a sheet bonded to the elastic body and performs printing by pressing the sheet against a printing object surface. The method includes a sheet fixing step of fixing the sheet at a periphery of a region in which the sheet is to be bonded to the elastic body; an elastic body placing step of placing the elastic body so that a bonding surface of the elastic body faces a bonding surface of the sheet that is fixed; a wax applying step of forming a wax layer on a surface of the elastic body; an adhesive applying step of applying an adhesive to at least one of the sheet and the elastic body that is provided with the wax layer on the surface thereof; and a pressing step of pressing the sheet and the elastic body against each other and bringing the sheet into close contact with the elastic body provided with the wax layer such that the adhesive is interposed therebetween while stretching the sheet along the surface.
US11325408B2 Device for driving a stamping foil, stamping station and machine, and method for controlling the driving of a stamping foil
A device for driving a stamping foil over a path through a stamping machine is disclosed herein. The driving device comprises two foil-introduction chain-like elements and a drive member coupled to the foil-introduction chain-like elements for driving the foil-introduction chain-like elements notably through a platen press of a stamping machine. The driving device further comprises at least one first load-measurement device comprising a first detector configured to measure a parameter indicative of the load applied by the drive member for driving the foil-introduction chain-like elements in a first direction, the at least one first load-measurement device being connected to a stamping-machine control unit configured to stop the driving by the drive member when the parameter indicative of the load applied by the drive member and measured by the first detector crosses a threshold.
US11325405B2 Printer with print head and support having head spring that urges print head
A printer includes a print head configured to print on a recording sheet, a platen roller attached to a frame in a rotatable manner, a support having a head spring attached thereto that urges the print head toward the platen roller, and a hold unit attached to the frame in a rotatable manner and having an engaging part that engages with a projection situated at a side end of the support, wherein the head spring is configured to urge the print head toward the platen roller when the projection is engaged with the engaging part, and wherein the hold unit is configured to be rotated to cause the engaging part to disengage from the projection.
US11325403B2 Printing apparatus
A printing apparatus includes a thermal head, a paper feed unit, a paper detection unit, an ink ribbon take-up unit, an detection unit, and a control unit. The thermal head transfers ink applied to an ink ribbon onto paper. The paper feed unit feeds paper stacked on a paper stacking unit and conveys the paper. The paper detection unit detects the fed paper. The ink ribbon takes-up unit take up the ink ribbon. The detection unit detects a printing start position of the ink ribbon. The control unit controls feeding of the stacked paper from the paper stacking unit, suspend the conveyance of the paper upon detection of the fed paper, take up the ink ribbon with the ink ribbon take-up unit, stop the ink ribbon take-up upon detection of the printing start position of the ink ribbon, and restart the conveyance of the paper with the paper feed unit.
US11325402B2 Printer apparatus with flapper attached to conveying route cover
A printer including a printing part which prints on a recording paper; a cutter part which cuts the recording paper; and a conveying part which includes a conveying route having a curving shape and through which the recording paper conveyed through the cutter part is conveyed; a conveying route cover which is attached to the conveying part and covers a portion of the conveying route; and a flapper which is provided at a curved portion of the conveying route, has a curved shape, and is rotatably attached to the conveying route cover so as to rotatably open or close relative to a main body of the printer, wherein the conveying route cover and the flapper are movable together so as to separate from or contact the main body.
US11325401B2 Printing apparatus and control method therefor
A printer for printing on rolled paper includes an air pressure sensor that detects air pressure, a platen that has a suction hole and is installed on a transport path of the rolled paper, a suction fan that sucks the rolled paper via the suction hole, and a control section that performs control for changing a rotation speed of the suction fan according to a detection result of the air pressure sensor.
US11325398B2 Image processing device generating dot data using machine learning model and method for training machine learning model
In an image processing device, a controller performs: acquiring target image data representing a target image; inputting first and second datasets into a machine learning model and causing the machine learning model to output first and second partial dot data; and generating dot data specifying a dot formation state for each of a plurality of pixels in a print image corresponding to the target image using the first and second partial dot data. The first dataset includes first partial image data and a first value for an input parameter. The second dataset includes second partial image data and a second value for the input parameter. The machine learning model outputs the second partial dot data different from the first partial dot data according to the second value being different from the first value even when the second partial image data is identical to the first partial image data.
US11325395B2 Printer including liquid discharge head
There is provided a printer including: a casing defining an internal space; a conveyor; a head; a tank, a first channel communicating the tank and the head with each other; a first pressure gauge; a first pump; a second channel communicating the tank and the head with each other; a second pressure gauge; and a second pump. The internal space includes a first space defined between a first virtual surface and a second virtual surface which are parallel to a conveyance direction and an up-down direction 7, and a second space which is different from the first space; the head is positioned in the first space; and the tank, the first pressure gauge, the first pump, the second pressure gauge, and the second pump are positioned in the second space.
US11325392B2 Printer
A printer includes an ink tank, a print head that performs printing by using ink in the ink tank, a light source that emits light into the ink tank, a sensor that outputs pixel data by detecting light incident from an ink tank side in a period during which the light source emits light, and a processing section that determines an ink amount by an output of the sensor. The processing section designates a reading area for the sensor, and determines an ink amount based on pixel data of the reading area output from the sensor.
US11325391B2 Method for operating a printing material processing machine by applying a varnish consumption prediction
A method for operating a printing material processing machine by using a computer includes acquiring print job parameters from print jobs for the printing material processing machine and machine parameters by using the computer, evaluating the acquired parameters to determine the machine state by using the computer, and requesting and providing fluid consumable materials for optimizing the operation of the machine on the basis of the determined machine state by using the computer. Maintenance measures carried out on the machine are optimized on the basis of the determined machine state, by using the computer.
US11325387B2 Biased print gaskets
In various examples, biased print gaskets can include a non-transitory machine-readable medium storing instructions executable by a processing resource to charge a material included in a gasket with a first bias voltage to repel print particles from a surface of the gasket, cease charging the material with the first bias voltage and charge the material with a second bias to attract print particles to a surface of the gasket.
US11325386B2 Liquid container device and liquid ejecting apparatus
A liquid container device includes: a liquid container having an inlet; a casing in which the liquid container is housed; and a cap lever having a cap configured to seal the inlet. The liquid container has an upper surface, and a visualization surface. The casing includes a cover configured to pivot and that protects the upper surface, a cap lever-engaging portion, a visualization portion having an opening, and a wall portion disposed on the +Z direction side with respect to the visualization portion. The cap lever includes an engageable portion configured to be engaged with the cap lever-engaging portion, and a body extending in the +Y direction from the engageable portion. A surface disposed so as to face the cover of the body is planar, and an end of the body in the +Y direction is separated from an end of the wall portion in the +Z direction.
US11325379B2 Fluid ejection dies
A fluid ejection die may include a number of fluid ejection chambers laid to correlate with a number of dividers formed in a fluid channel layer such that adjacent fluid ejection chambers are alternatively arranged on a relatively higher-temperature side of the fluid ejection die and a relatively lower-temperature side of the fluid ejection die.
US11325376B2 Drive circuit and liquid ejecting apparatus
A drive circuit includes a drive signal output circuit that outputs a drive signal supplied to the piezoelectric element and a first constant voltage signal that is constant at a first voltage value; a switch circuit having one end electrically coupled to an output terminal of the drive signal output circuit and the other end electrically coupled to the first terminal of the piezoelectric element, and a reference voltage signal output circuit that is electrically coupled to the second terminal of the piezoelectric element and outputs a second constant voltage signal which is constant at a second voltage value, in which before the reference voltage signal output circuit starts to output the second constant voltage signal, the one end and the other end of the switch circuit are controlled to be non-conductive, and the drive signal output circuit outputs the first constant voltage signal.
US11325370B2 Fluidic die with low voltage monitoring circuit including high voltage tolerant transistor
A fluidic die including fluid chambers, each including an electrode exposed to an interior of the fluid chamber and each having a corresponding fluid actuator operating at a first voltage level. Monitoring circuitry, operating at a second voltage level lower than the first voltage level, includes a select transistor and a pulldown transistor for each fluid chamber to selectively couple to the electrode, at least the select transistor being a high voltage tolerant transistor to operate at the second voltage in a normal operating condition and having a breakdown voltage level greater than the first voltage level to prevent a fault current from flowing into the select transistor from the electrode in a fault condition if the fluid actuator short-circuits to the electrode.
US11325367B2 Smooth film laminated elastomer articles
A method for manufacturing at least one elastomeric article is provided. The method includes placing into a mold an assembly of an uncured elastomeric sheet, a first film fully covering the elastomeric sheet and a second film covering the first film, such that the second film is in contact with and positioned between the first film and an interior surface of the mold. The method further includes curing the assembly in the mold, such that the first film is laminated onto the elastomeric sheet thereby forming the at least one elastomeric article.
US11325365B1 Laminating apparatus
A laminating apparatus is provided, which is capable of producing a laminate having a highly planarized surface. The laminating apparatus is arranged to laminate a film on an irregular surface of a substrate having irregularities, and includes a vacuum laminating device which brings the film into close conformal contact with the substrate under reduced pressure to form a first temporary laminate, a first flat press device which presses the first temporary laminate to form a second temporary laminate having a substantially planarized irregular surface, and a second flat press device which presses the second temporary laminate under different conditions from the first flat press device to form a product laminate having a planar surface.
US11325362B2 Layered polyester film
To provide a layered polyester film having excellent mechanical properties, transparency, heat resistance, and gas barrier property. A layered polyester film including a polyester film and a thin film layer, wherein the polyester film is a biaxially oriented polyester film including a dicarboxylic acid component containing mainly a furandicarboxylic acid and a glycol component containing mainly ethylene glycol, the covering layer is formed on at least one surface of the polyester film, and the layered polyester film has a plane orientation coefficient ΔP of not less than 0.100 and not more than 0.200, and a thickness of the layered polyester film is not thinner than 1 μm and not thicker than 300 μm.
US11325360B2 Multilayer body, packaging container, and food storing method
A multilayer body comprising a sealing layer (A) comprising a thermoplastic resin, an oxygen absorption layer (B) comprising a thermoplastic resin and iron powder, and an oxygen barrier layer (D) having oxygen barrier properties, the layers being laminated in a described order, wherein at least one of the sealing layer (A) and the oxygen absorption layer (B) comprises an ionomer as the thermoplastic resin.
US11325358B2 Dual shell dental appliance and material constructions
Improved dental appliances and polymeric sheet compositions are disclosed. The polymeric sheet compositions are useful for making dental appliances having outer layers comprised of a material having a modulus of from about 1,000 MPA to 2,500 MPA (“hard”) and an inner core comprised of elastomeric material or materials having a modulus of from about 50 MPa to 500 MPa (“soft”), which exhibit improved flexibility and strength, and better stain and tear resistance than currently available materials and dental appliances.
US11325355B2 Process for manufacturing a fibrous preform filled with particles
A process for manufacturing a fibrous preform filled with particles, includes forming the filled preform by compacting a stack of a plurality of fibrous strata impregnated by a suspension of ceramic oxide particles in a liquid medium, wherein the liquid medium includes at least one compound having a saturated vapor pressure of less than 2.3 kPa at 20° C., this compound being present in a weight content of greater than or equal to 30% relative to the total weight of the suspension.
US11325354B2 Interlayer film for laminated glass
Provided is an interlayer film for laminated glass which is excellent in sound insulation property and has improved sound insulation performance not only in a coincidence region but also in a mass-dominated region. The interlayer film for laminated glass includes a sound insulating layer which is formed from a composition (A) containing at least one resin (a1) selected from a thermoplastic resin and a thermosetting resin, wherein a tan δ obtained when a dynamic viscoelasticity of a sheet, which is obtained by molding the composition (A) to have a thickness of 0.8 mm, is measured at a frequency of 0.3 Hz in a tension mode has a maximal value at a temperature TA (° C.), TA (° C.) is in a range of −50 to 50° C., and the tan δ at TA (° C.) is 2.5 or more.
US11325353B2 Composite pane with an electrical load
A composite pane with an electrical load, includes an outer pane and an inner pane that are joined to one another via a thermoplastic intermediate layer, wherein the thermoplastic intermediate layer has a recess that has a receiving opening, the receiving opening is dimensioned such that it is designed for accommodating the electrical load in the recess, and the electrical load is arranged in the recess.
US11325352B2 Leakage current detection and control for one or more electrically controllable privacy glazing structures
An electrical characteristic of a privacy glazing structure and indicative of a health of the privacy glazing structure can be measured at a first time and at a second time later than the first time. In response to detecting a change in the electrical characteristic indicating a change in the health of the privacy glazing structure, one or more parameters of an electrical drive signal can be adjusted to compensate for the change in the health of the privacy glazing structure. The electrical characteristic can be measured at a plurality of times after the second time and compared to the electrical characteristic measured at the first time. If, at any of the plurality of times, the measured electrical characteristic differs from the electrical characteristic measured at the first time by more than a threshold amount, one or more parameters of the electrical drive signal can be adjusted.
US11325351B2 Method for fabricating display panel
A method for fabricating a display panel including a bending area includes: providing a substrate; forming a first flexible layer on the substrate; forming an organic layer on the first flexible layer, wherein a wavelength of light absorbed by the organic layer is different from a wavelength of light absorbed by the first flexible layer; irradiating a part of the organic layer in the bending area with a laser to make at least a portion of the part of the organic layer a carbonized layer, thereby forming a spacer layer; forming a second flexible layer covering the first flexible layer and the spacer layer, wherein the first flexible layer and the second flexible layer are made of a same material and separated by the spacer layer; and cutting a part of the substrate and a part of the first flexible layer in the bending area.
US11325350B2 Films and laminates for use in packaging reactive compounds
The present present disclosure relates to a laminate film including a water resistant or oxygen resistant base layer, and co-extrusion layer. The coextrusion layer may include a tie layer and a contact layer, and the contact layer may include a polymer such as cyclic olefin copolymer, a polyamide, or an ethylene vinyl alcohol. A total loading of the tie layer may be in the range of 3-9 g/m2 and wherein a loading of the contact layer is: loadingcontact=x*loadingtie, wherein loadingcontact is the loading of the contact layer, loadingtie is the total loading of the tie layer, and x is in the range of 0.8 to 3.
US11325348B2 Metal-carbon composites and methods for their production
A method for producing a carbon nanotube-metal composite in which carbon nanotubes are layered on a metal substrate, the method comprising: (i) depositing a liquid, in which carbon nanotubes are suspended, onto said metal substrate; (ii) during or after step (i), subjecting said liquid to a shearing force sufficient to spatially confine the liquid to induce at least partial alignment of said carbon nanotubes on said metal substrate; and (iii) removing said liquid to produce said carbon nanotube-metal composite; wherein, after step (iii), the lengthwise dimensions of said carbon nanotubes are adhered to and oriented parallel with said metal surface, and said carbon nanotubes are at least partially aligned with each other. In some embodiments, the liquid is deposited in the form of droplets, and the droplets are subjected to a shearing force to cause them to elongate, which induces at least partial alignment of the carbon nanotubes.
US11325345B2 Fiber-bound engineered materials formed utilizing carrier screens
A method of forming a fiber-bound engineered material utilizing carrier screens is provided that imparts an intended characteristic at an intended relative location. Also provided are articles formed of fiber-bound engineered materials manufactured utilizing carrier screens. A fiber layer is placed adjacent at least one carrier screen and entangled with additional fibers in a manner to create a non-uniform engineered material. The lack of uniformity of a fiber-bound engineered material may be accomplished through manipulation of the fibers and/or through fiber binding a scrim. The fiber layer binds with additional fibers through entanglement such that a mechanical connection between the entangled fibers is provided. This entanglement allows the fibers to bind without supplemental adhesives, interlacing, or connections.
US11325343B2 Ion-doped two-dimensional nanomaterials
Ion-doped two-dimensional nanomaterials are made by inducing electronic carriers (electrons and holes) in a two-dimensional material using a captured ion layer at the surface of the material. The captured ion layer is stabilized using a capping layer. The induction of electronic carriers works in atomically-thin two-dimensional materials, where it induces high carrier density of at least 1014 carriers/cm2. A variety of novel ion-doped nanomaterials and p-n junction-based nanoelectronic devices are made possible by the method.
US11325340B2 Dunnage conversion machine and method
A dunnage conversion machine (36) converts a sheet stock material into a dunnage product that is relatively thicker and less dense than the stock material, but is relatively thin and sufficiently flexible to function as a protective wrap. The conversion machine includes a feed mechanism (40) that advances a sheet stock material therethrough and a connecting mechanism (42) downstream of the feed mechanism. The connecting mechanism retards the passage of the sheet stock material therethrough by feeding the stock material therethrough at a slower rate than the feed mechanism feeds the stock material to the connecting mechanism. This causes the stock material to randomly crumple in a longitudinal space between the feed mechanism and the connecting mechanism. The connecting mechanism connects multiple overlapping layers of sheet stock material together as they pass therethrough, including connecting at least one crumpled sheet to one side of one other sheet.
US11325331B2 Tire manufacturing method
In a manufacturing method of a tire which manufactures a side-wall rubber as a constituent member of the tire by winding a rubber strip formed of unvulcanized rubber on a carcass ply serving as a rotating body, the method includes the steps of: winding the rubber strip prior to vulcanization in a spiral manner having a partially overlapping region, so that at least part thereof is exposed at an outer surface, and another portion thereof is covered by the rubber strip after being wound; and arranging an electronic component so that the electronic component is positioned in the partially overlapping region of the rubber strip or between the carcass ply, etc. serving as the lower layer member of the rubber strip and the rubber strip, in the winding step or an earlier step thereto.
US11325329B2 Pre-stressed fiber reinforcing member and method for its manufacture
A composite structural article (100) includes a polymeric body (35) having a first major surface (24) and an opposing second major surface (22) and a rib element (30) extending away from the first major surface. A reinforcing member (10) is embedded within a free end portion (34) of the rib member (30). The reinforcing member includes an elongated polymer rod having a rod length and a plurality of co-extending continuous fibers (20), embedded and distributed within the elongated polymer rod. The fibers are under tension and may have a helical or twisted configuration along the rod length.
US11325327B2 Ball bat with one-piece multi-wall barrel portion
A method of forming a barrel portion including obtaining a mandrel shaped to define at least an inner surface of a barrel portion of the bat, wrapping a first plurality of layers of fiber composite material about the mandrel, placing a removable material over a first portion of the first plurality of layers, and wrapping a second plurality of layers of fiber composite material over the removable material and the portion of the first plurality of layers not covered by the removable material for form an assembly. The method further includes separating the mandrel from the assembly, inserting an expandable member within the assembly, inserting the assembly into a barrel-forming mold, and molding the assembly in a single molding cycle, curing the first and second layers with the removable material to form the barrel portion of the bat, and removing the removable material and the member from the barrel portion.
US11325325B2 Method for manufacturing fiber reinforced plastic molded body
Provided is a method for manufacturing a fiber reinforced plastic molded body, the method including: performing thermocompression molding, by using a molding die, on a molding precursor which is obtained by arranging a prepreg including a thermosetting resin and a fiber around a thermoplastic solid body.
US11325324B2 Automated fiber bundle placement apparatus
A guide mechanism includes a support member that supports a plurality of tow guides provided corresponding to each of fiber bundles, and a support mechanism that supports the support member with respect to an arm, and the support mechanism is configured such that the support member is displaceable in a width direction orthogonal to an extending direction of the arm in a plan.
US11325320B2 System and method for welding thermoplastic components to create composite structure
A system and method for welding thermoplastic components by positioning and moving a heated plate between the components to melt their respective faying surfaces, and as the plate moves, pressing the components together so that the melted faying surfaces bond together as they cool and re-solidify, thereby creating a composite structure. The plate has a heated portion which is positioned between and heated to melt a portion of the first and second faying surfaces. A manipulator mechanism moves the plate along an interface from between the portion to between a series of subsequent portions of the first and second faying surfaces, thereby welding the thermoplastic components along the entire interface to create the composite structure. The heated portion may contact the faying surfaces and melt them through conduction, or may be suspended between them and melt them through radiation and convection.
US11325318B2 Bonding objects together
The relates to a method of mechanically securing a first object to a second object and includes the steps of: providing the first object including thermoplastic material in a solid state, providing the second object with a generally flat sheet portion having an edge, positioning the first object relative to the second object and bringing the first object and the second object to a relative movement to each other. The relative movement includes a rotational movement, such that a melting zone including flowable thermoplastic material is formed and such that thermoplastic material of the melting zone flows around the edge to at least partially embed the edge in the thermoplastic material. The invention further concerns a connector that is suitable for being used in a method according to the invention.
US11325315B2 Composition to produce support sub-structures for 3D photopolymer jetting
The present invention is directed to a UV-curable composition capable of producing a 3D-printed support sub-structure for photopolymer jetting, and to a 3D-printing processes using said support material composition, and to a 3D-printed articles obtainable with said 3D-printing processes. The composition comprises a N-acryloyl glycinamide type monomer, anoptional hydrophilic co-monomer, a hydrophilic dispersion medium or water, a photoinitiator, and an optional functional additive or combination thereof, at specific contents.
US11325311B2 Information processing apparatus, non-transitory computer readable medium, and three-dimensional object forming system
There is provided an information processing apparatus. A receiving unit receives a data of printing. An output unit outputs image data of each of plural elements which are parts of recording media, if the receiving unit receives print data including height information of a three-dimensional object at positions of each pixel of image data on a two-dimensional image is generated such that the three-dimensional object is formed by stacking the plural elements, and the image data is generated from the height information of the three-dimensional object at the positions of the each pixel.
US11325310B2 Optimizing print speed and orientation for 3D printing based on multiscale convolutions
An optimal printing speed and orientation for an object to be manufactured using an additive manufacturing process in which a photo-curable resin is cured through exposure to radiation are estimated by determining, for pixel maps defining cross-sections of the object, a critical size of a convolution kernel which provides an activation map having a maximum activation pixel value less than or equal to a predetermined threshold value. For each respective pixel map, a printing time is estimated as a function of an adjusted base lift velocity and base lift height of the printing apparatus. The optimal printing speed and orientation are then estimated as a minimum value of a function of the printing times for all respective pixel maps of the cross-sections of the object at each of a plurality of possible orientations of the object.
US11325306B2 Build material container
Examples of the present disclosure relate to a build material container for a three-dimensional printing system. The container has an external casing with an upper surface, a lower compartment to receive a build material reservoir, at least one load-bearing element, and an upper compartment below the upper surface. The upper compartment and the lower compartment are separated by a lower surface. The at least one load-bearing element is arranged below the lower surface. The upper compartment has stiffening members arranged to distribute load received from the upper surface to the at least one load-bearing element.
US11325299B2 Additive manufacturing via optical aperture division multiplexing
Systems, devices, and methods for additive manufacturing as disclosed allow for improved optical access to a build platform. In at least some embodiments a multiplexing optic of an additive manufacturing device is configured to multiplex an arbitrary number of optical paths to a build platform along a substantially common optical axis by dividing a theoretical input aperture of the multiplexing optic into a plurality of sub-apertures. Each sub-aperture can independently receive and direct an optical path to the build platform. An optical path can be a light path from a light source or an optical process monitoring path from an optical process monitoring system or optical process monitoring device. In some embodiments, an optical path can enter the multiplexing optic off-axis and/or off-angle with respect to an optical axis of the multiplexing optic. The multiplexing optic can include one or more lens elements and/or one or more mirror elements.
US11325297B2 Injection molding mold, and injection molding method for hollow article
An injection molding mold including a neck mold forming an outer surface of a neck portion of a hollow article, an injection cavity mold forming an outer surface of a body portion of the hollow article, and an injection core mold forming an inner surface of the hollow article, in which the injection core mold includes an outer core mold forming an inner surface of the neck portion including an inner screw portion and, while rotating along the inner screw portion, being movable along a rotation axis thereof, and an inner core mold forming an inner surface of the body portion of the hollow article having a smaller diameter than that of the neck portion and being linearly movable inside the outer core mold along the rotation axis.
US11325293B2 Insert molding and insert molding quality determination device
An insert molding includes a lithium-ion battery, temperature measurement element and a pressure measurement element disposed close to the lithium-ion battery to sense temperature and pressure around the lithium-ion battery during insert molding; and a molding resin that covers the lithium-ion battery, the temperature measurement element, the pressure measurement element and a cover member.
US11325291B2 Dual torque and injection molding device
A tool for driving a threaded fastener includes a driver head, a motor, and an injector. The driver head includes a spindle rotatable about an axis. A distal end of the spindle defines a plurality of drive surfaces configured to engage mating drive surfaces on the fastener to rotate the fastener about the axis. The driver head defines a fluid passage having an outlet proximate to the distal end of the spindle. The motor is drivingly coupled to the spindle to rotate the spindle about the axis. The injector is coupled to an inlet of the fluid passage and configured to feed a liquid insulator through the fluid passage.
US11325282B2 Method of manufacturing a composite workpiece
Methods of manufacturing composite workpieces that include positioning a heat-generating element proximate to an uncured composite workpiece, triggering the heat-generating element to produce an exothermic chemical reaction or exothermic physical reaction so that the temperature of the uncured composite workpiece is raised to a predetermined first temperature, and curing the composite workpiece while it is at a temperature that is at least the predetermined first temperature.
US11325280B2 Waste management system
A waste management system, primarily intended to be for waste floating in water, though it can also be used on land. A shredding device will reduce the size of the particles of waste. Ocean water is removed by a drying device. The dried waste material is cryogenically frozen using liquid nitrogen or other suitable means. The frozen waste material is then pulverized and ground into a powder. The powder may then be sprayed into a gas-filled chamber and heated. Temperature, pressure and humidity are maintained within the chamber for more than one minute. Microwave or other radiation and catalysts may be used to enhance the process of extraction. The processed material is then removed from the chamber. Carbon and water may be recycled. The carbon may be used as fuel by the ship. Water may also be used by the ship or returned to the ocean in a non-toxic condition.
US11325279B2 Architectural blocks with stone-like appearance and method of manufacture
The present disclosure describes architectural blocks configured to give the appearance of real cut stone. A plaster composition may be applied to one or more surfaces of a block, such as a concrete masonry unit (CMU) to form an architectural block having the appearance of cut stone. The plaster composition includes a cementitious component, such as white Portland cement, a limestone aggregate component, and optionally an adhesive component. The limestone aggregate component includes a fine sand portion and a coarse sand portion that effectively enable the appearance of cut stone after finishing of the plaster surface via sanding and/or polishing.
US11325276B2 Engineered timber products, components and methodologies
A method of drying sticks, a related apparatus, resultant product and its uses where the method involves presenting a plurality of sticks in parallel as a single layer, pressing each stick with a bank of pressing members on and/or into at least one face of the sticks, each with plurality of protuberances, thereby to constrain the sticks against crook, and drying the sticks when so constrained. Preferably each bank of pressing members is an underside of a frame or lattice of a stack of such frames or lattices able to receive such a single layer of sticks between adjacent overlying/underlying frames or lattices, the protuberances preferably being only downwardly directed.
US11325269B2 Cutting tool
A cutting tool is provided which may include a first blade and a second blade, where the first blade is coupled to the second blade at a first pivot point, where the first blade defines a cam follower and pivots relative to the second blade about a first pivot axis through the first pivot point; and a lever pivotably coupled to the second blade at a second pivot point, where the lever defines a cam surface and pivots relative to the second blade about a second pivot axis through the second pivot point, where the second blade is driven toward the first blade in response to the lever being advanced toward the first pivot point and the cam follower translating along the cam surface.
US11325265B2 Apparatuses, systems, and methods for the grasping of objects
Provided herein is an apparatus and system to increase the capacity for grasping or engagement of an object using an accessory tool. Methods of increasing the capacity of a tool can include: engaging an accessory tool with a tool, where the tool includes a first vacuum cup and the accessory tool includes one or more second vacuum cups; securing the tool to the accessory tool with a securing mechanism; drawing a vacuum through the first vacuum cup, where the vacuum is drawn through the one or more second vacuum cups in response to drawing a vacuum through the first vacuum cup while the accessory tool is engaged with the tool; and grasping an object with the second one or more vacuum cups in response to vacuum drawn through the one or more second vacuum cups and the one or more second vacuum cups engaging a surface of the object.
US11325262B2 Robot, robot control system, robot control method, and non-transitory storage medium
A robot includes an operator and a processor. The operator is configured to cause a robot to operate. The processor acquires adornment information indicating an adornment that is applied to the robot, the adornment information being obtained based on a captured image of the robot. The processor controls the operator to perform an operation corresponding to the acquired adornment information.
US11325258B2 Guidance apparatus and method for failure recovery
To assist appropriately in performing a recovery operation of a device. A guidance information presentation apparatus includes: a guidance information receiving unit configured to acquire guidance information including access information and safety information, the access information including a moving route to reach an estimated location of a failure in an apparatus as a recovery target, and an operation procedure, the safety information indicating safety of the moving route and the operation procedure in the access information; and a guidance information displaying unit configured to perform, on a basis of the guidance information, notification for a guidance of the moving route to the estimated location of the failure in the apparatus as the recovery target, and the operation procedure, and notification that indicates the safety of the moving route and the operation procedure.
US11325255B2 Method for controlling robot and robot device
A method for controlling a robot includes: establishing a reference coordinate system; capturing a user's gaze direction of an indicated target; acquiring a sight line angle of the robot; acquiring a position of the robot; acquiring a linear distance between the robot and the user; calculating in real time a gaze plane in a user's gaze direction relative to the reference coordinate system based on the sight line angle of the robot, the position of the robot and the liner distance between the robot and the user; and smoothly scanning the gaze plane by the robot to search for the indicated target in the user's gaze direction.
US11325253B2 Autonomous device for transporting items
A fully autonomous mobile robot is provided that transports items from one area to another. The mobile robot includes a variety of mechanisms that capture an item from a first surface and moves the item within the confines of the mobile robot. The item can then be transported to another surface either within the confines of the mobile robot or to another location.
US11325250B2 Robot with rotatable arm
A mobile robot is configured for operation in a commercial or industrial setting, such as an office building or retail store. The mobile robot can have a motorized base and a robot body on the motorized base, the robot body including a rotatable ring that rotates horizontally around the robot body. A mechanical arm that can contract and extend relative to the robot body is coupled to the rotatable ring and performs a plurality of actions. A controller of the mobile robot provides instructions to the rotatable ring and the mechanical arm and can cause the mechanical arm to open a door, take an elevator to move to a different floor, and test whether a door is locked properly.
US11325247B2 Robotic arm control method and apparatus and terminal device using the same
The present disclosure provides a robotic arm control method as well as an apparatus and a terminal device using the same. The method includes: obtaining a current joint angle of each of M joints of the robotic arm; obtaining a reference included angle based on the current joint angle of each of the M joints of the robotic arm; determining an expected included angle corresponding to the robotic arm within a target angle range based on the reference included angle and the preset included angle related evaluation function; and controlling the robotic arm based on the target joint angles of the M joints.
US11325236B2 Insulated multi-tool
An insulated multi-tool comprising a pair of opposing jaws, a pair of opposed handles operatively connected to the jaws relative to a pivot to force the jaws into a clamping position about an object, at least one of the opposed handles having a tool-receiving pocket, at least one tool stored in the tool receiving pocket, the at least one tool pivotally attached relative to the tool receiving pocket for movement between a stored position in which the at least one tool is stored within the tool receiving pocket and an open, use position in which the at least one tool is located relative to at least one of the opposed handles for use, and wherein the a pair of opposed handles are electrically insulated from both the pair of opposing jaws and each at least one tool.
US11325234B2 Hammer tacker
A hammer tacker is provided, including a grip portion and a body portion; a magazine, including a rail, at least partially received in the housing, being movable relative to the housing between a stapling position and a staple-installing position, including an outlet disposed at a front end of the body portion; a biasing mechanism, including a push member movably mounted to the rail and a constant force spring which is rollable, the constant force spring being positionally attached to the rail through a connection portion and located at a front end of the magazine, and the constant force spring being attached to an inner face of the push member, the push member being movable to be correspondingly above or beyond the connection portion; a striking mechanism, mounted to the body portion and configured to strike at least one staple installed in the magazine.
US11325233B2 Driving tool
A nailing machine includes a tool body, a flywheel (40), a driver (3), a pressing mechanism and a return mechanism. The pressing mechanism includes a spring mechanism and a pressing roller (87). The pressing roller (87) is supported to be rotatable around a rotation axis (A2) and movable in a left-right direction, and configured to press the driver (3) toward the flywheel (40) by a biasing force of the spring mechanism in a nail-driving process in which the driver (3) moves from an initial position to a nail-driving position, to thereby enable transmission of the rotational energy to the driver (3). The pressing mechanism is configured such that the position of the pressing roller (87) relative to the driver (3) changes in the left-right direction between the nail-driving process and a return process, thereby making it impossible for the pressing roller (87) to press the driver (3) in the return process.
US11325230B2 Tool extension rod
A tool extension rod includes a main piece, a sliding sleeve, and a magnetic assembly. The sliding sleeve is slidably sleeved onto the main piece. When the sliding sleeve moves between a first position and a second position, the magnetic assembly is movable along an axial direction.
US11325227B2 Sprinkler head removal and installation device
A sprinkler head removal and installation device includes a tube that has a first end, which is closed, and a second end that is open. The tube has an inner diameter that is complementary to a diameter of a set of groves that is positioned in a top of a sprinkler head. Each of a plurality of teeth is coupled to and extends from the second end of the tube is configured to be inserted into a respective groove of the set of grooves as the top of a sprinkler head is partially inserted into the tube through the second end. An aperture that is centrally positioned in the first end of the tube is configured for insertion of a drive of a socket wrench, positioning a user to selectively turn the socket wrench to remove and install the sprinkler head.
US11325224B2 Method of monitoring a dressing process and polishing apparatus
A method of monitoring dressing of a polishing pad is provided. The method includes: rotating a polishing table that supports the polishing pad; dressing the polishing pad by pressing a dresser against the polishing pad while causing the dresser to oscillate in a radial direction of the polishing pad; calculating a work coefficient representing a ratio of a frictional force between the dresser and the polishing pad to a force of pressing the dresser against the polishing pad; and monitoring dressing of the polishing pad based on the work coefficient.
US11325222B2 Porous polyurethane polishing pad and method for manufacturing same
An embodiment relates to a porous polyurethane polishing pad for use in a chemical mechanical planarization (CMP) process of semiconductors and a process for preparing the same. In the porous polyurethane polishing pad, the polishing performance (or polishing rate) thereof can be controlled by adjusting the size and distribution of pores in the polishing pad.
US11325218B2 Worm polishing method and device thereof
Loopback rolls which can transfer and guide a polishing tape (T) along a perimeter of a pressure contact roll (R) is provided, the pressure contact roll having a tapered peripheral edge having a top edge and a pair of slant edge faces formed on a periphery of the pressure contact roll, by which the polishing tape can be bent into a substantially V-shape in cross section, and a switchable pressure contact mechanism is switchably provided which pressure contacts each of bent portions of the polishing tape, which is bent into the substantially V-shape in cross section by the tapered peripheral edge, to one tooth face (B1) or the other tooth face of a worm.
US11325217B2 Accessory for an electric power tool
An accessory for an electric drill is disclosed as including a dust box for receiving abraded materials produced by an electric drill on a workpiece, the dust box including an internal cavity, a first longitudinal end with a first opening communicating with the internal cavity, an opposite second longitudinal end with a second opening communicating with the internal cavity, and a brush or a disc. When a drill bit of the electric drill is received into the internal cavity of the dust box through the second opening, the brush or disc is releasably engageable with the drill bit for simultaneous rotational movement about a longitudinal axis of the drill bit.
US11325209B2 Welding monitoring system
To improve quality control of welding, there is included in resistance welding: a magnetic field measuring unit (205) disposed around a welded part and configured to measure a local current at the welded part; a high-speed camera (202) configured to capture an image for measuring local temperature at the welded part from variation of luminance of emission by capturing light emission state of the welded part; a comparison determination unit (106) configured to determine whether or not at least one of current information and temperature information has an abnormal value by comparing the current information calculated based on magnetic field information acquired from the magnetic field measuring unit with past current information and comparing the temperature information measured from an image of the high-speed camera (202) with past temperature information.
US11325207B2 Systems and methods for additive manufacturing
An additive manufacturing system includes a plurality of laser devices, a plurality of first scanning devices, and an optical system. The optical system includes an optical detector and a second scanning device. The plurality of laser devices are each configured to generate a laser beam. The plurality of first scanning devices is each configured to selectively direct the laser beam from a laser device of the plurality of laser devices across a powder bed. The laser beam generates a melt pool in the powder bed. The optical detector is configured to detect electromagnetic radiation generated by the melt pool. The second scanning device is configured to direct electromagnetic radiation generated by the melt pool to the optical detector. The optical system is configured to detect a position of the laser beams in the melt pool.
US11325201B2 Resistance welding apparatus
A welding gun includes a proximity restricting mechanism that is provided between a shaft and a cover member in a manner to surround the shaft and to be displaceable relative to the shaft in an axial direction in accordance with expansion and contraction of the cover member, and that restricts the cover member from approaching too closely the shaft.
US11325197B2 Tool holder device for broaching and slotting
The tool holder device for broaching and slotting, comprising: one main frame associated with one machine adapted to machine one workpiece; one working assembly associated with the main frame and comprising one supporting bar movable longitudinally along a first axis and a guiding mechanism for the supporting bar movable longitudinally along the first axis; one tool associated with the supporting bar and adapted to machine the workpiece; angular adjustment mechanism for adjusting the supporting bar, interposed between the main frame and the guiding mechanism and adapted to rotate the supporting bar around a second axis substantially orthogonal with respect to the first axis; and straight adjustment mechanism for adjusting the tool with respect to the supporting bar, interposed between the tool and the supporting bar, the straight adjustment mechanism being adapted to adjust the position of the tool along the second axis.
US11325196B2 Double-sided, polygonal cutting insert with alternating concave and convex cutting edges
A double-sided, polygonal cutting insert includes a first surface and a second surface opposite the first surface. A plurality of side surfaces extend between the first surface and the second surface. A plurality of primary concave cutting edges are formed at an intersection between the plurality of side surfaces and the first and second surfaces, and a plurality of convex wiper edges are formed at an intersection between the plurality of side surfaces and the first and second surfaces. Each wiper edge has a step extending radially outward from a respective side surface. The cutting insert is mounted in a cutting tool such that the primary cutting edge and a wiper edge contact a workpiece to produce a high-quality surface finish on the workpiece.
US11325190B2 Additive manufacturing method and machining-path generation method
An additive manufacturing method includes: forming first and second linear beads parallel to each other under a same predetermined formation condition such that a gap having a predetermined width is formed between the first and second linear beads; forming a third linear bead in the gap under the same formation condition; forming, after forming the third linear bead, the linear bead that is formed as an even-numbered line under the formation condition such that the linear bead is parallel to the first linear bead and a gap having a predetermined width is formed between the linear bead formed as an even-numbered line and a linear bead formed two lines before; and forming, after forming the third linear bead, the linear bead that is formed as an odd-numbered line in the gap between the linear bead formed immediately before and the linear bead formed three lines before under the formation condition.
US11325186B2 Method for manufacturing sintered component, sintered component, and drill
Provided is a method for manufacturing a sintered component, which can suppress occurrence of edge chipping when a through-hole is formed in a powder-compact green body and also has a good productivity. The method for manufacturing a sintered component includes a molding step of press-molding a raw material powder containing a metal powder and thus fabricating a powder-compact green body; a drilling step of forming a hole in the powder-compact green body using a drill; a sintering step of sintering the powder-compact green body after drilling, wherein the drill used for drilling has a circular-arc shaped cutting edge on a point portion thereof.
US11325184B2 Method for producing a powder-metallurgical product
A method for producing a powder-metallurgical product, in particular a bearing element or a motor component, is provided. According to the method, a metal powder, typically with a grain size between 2 μm and 15 μm, is melt-metallurgically produced and agglomerated into a powder mixture having a grain size smaller than 400 μm by organic binders and waxes. Subsequently, the agglomerated powder mixture is formed into a green body typically by way of uniaxial pressing and the formed green body thermally debindered. Finally, the debindered green body is sintered typically at temperatures of 1000° C. to 1300° C. and the sintered body reworked into the powder-metallurgical product.
US11325183B2 Surface-modified metal compound particles, and method for producing surface-modified metal compound particles
Provided are surface-modified metal compound particles comprising metal compound particles which are surface-modified with one or more types of carboxylic acid selected from a methacrylic acid, an acrylic acid, and a propionic acid, and a 12-hydroxystearic acid, wherein a portion or all of the one or more types of carboxylic acid selected from a methacrylic acid, an acrylic acid, and a propionic acid is a carboxylic acid (protonated) type.
US11325177B2 Die adjustment mechanism
A die adjustment mechanism, includes a base, the base is provided with a die that can apply pressure on the workpiece. The die includes multiple modules arranged sequentially and capable of sliding laterally relative to the base. The base is further provided with a slide rest/slide rests capable of sliding laterally relative to the base. Each slide rest is provided with a shifting fork which can be clamped with a module or can be clamped between two adjacent modules. Each slide rest is provided with a drive component capable of driving the shifting fork to be clamped with the module or be clamped between the two adjacent modules. Using this mechanism, bending and pressing of multiple sides of the metal plate can be completed by the same machine and the production efficiency is greatly improved.
US11325176B2 Multiple stroke slotting of planar workpieces
A method for multiple-stroke slotting of planar workpieces includes positioning a workpiece relative to a slotting tool having a punch and a die, moving the punch and the die relative to one another, moving the slotting tool and the workpiece relative to one another, slotting a workpiece by a slot length during a sectioning slot stroke and at least one subsequent slotting stroke in a sectioning phase, and performing strokes in form of slotting strokes and at least one trimming stroke during the relative movement of the punch and the die in a working phase. The subsequent slotting stroke is performed prior to the trimming stroke, and the slot length exceeds a maximum attainable slot length during the trimming stroke. The workpiece and the slotting tool are moved relative to one another by at least one feed movement between the strokes.
US11325173B2 Machine for bending metal products and corresponding bending method
Machine for bending metal products (B) includes a drawing unit (11) configured to feed at least one metal product (B) along an axis of feed (D) and toward a bending unit (12) and a shearing unit (14) configured to shear the metal product (B). The bending unit (12) is mounted on a translating platform (13) able to be translated in a direction of translation (T) transverse to the axis of feed (D), and at least one part of the shearing unit (14) is mounted on the translating platform.
US11325168B2 Dissolving silicate scale
The present disclosure includes arrangements, systems, and methods for removing mineral deposits. Disclosed is an aqueous solution within a container, with the container containing mineral deposits. The aqueous solution submerges the mineral deposits and may include at least one acid, or a combination of an organic acid and an inorganic acid in percentages that allow the replacement of toxic dangerous chemical ingredients. Disclosed also is a cathode and an anode within the container that are at least partially submerged within the aqueous solution. A direct current power source is configured to direct a voltage across the cathode and the anode to generate an electrical charge gradient within the aqueous solution.
US11325164B2 Machining swarf removing apparatus
A machining swarf removing apparatus includes a left and a right machining swarf removing units. When removing machining swarf adhered to a recovery box, the left machining swarf removing unit is placed in removal starting position. A brush enters an insertion-ready state in which transverse direction thereof is oriented in a second direction D2. The brush is moved to an insertion position for insertion into the recovery box, then the brush is rotated to enter a machining swarf removal-ready state in which a longitudinal direction thereof is oriented in the second direction D2. The left machining swarf removing unit is moved to remove the machining swarf adhered to the recovery box by the brush, while a left rod vibrating device is driven to vibrate a rod, vibrating the brush attached to the rod.
US11325151B2 Process for coating a substrate with a carbon-based material
A coating process is described that coats a coil-to-coil continuous substrate with a graphene-like coating. The coating process includes cleaning and activating a substrate, applying a graphene oxide dispersion to the substrate, drying the coated sub-strate, and exposing the dried coating to VUV radiation under a dry atmosphere. The atmosphere for the last step includes one or more inert gases and optionally one or more reactive gases to repair defects in the coating and/or to functionalize the coating. This coating process allows for the formation of a polygranular graphene-like coating intimately in contact with the substrate. The graphene-like coating coats the substrate with multiple monolayers of graphene in a continuous manner.
US11325148B2 Rod and liquid paint suction assembly and method of manufacturing such a rod
A liquid paint suction rod including an upstream tube, a flexible intermediate tube and a rigid downstream tube, which includes a downstream elbow, the downstream tube delimiting a series of passage sections defining centers constituting a trajectory, the downstream elbow extending along a curved part of the trajectory, along which the passage sections are substantially discoid and have a preferably constant diameter; in order to avoid imposing too great a curve on the intermediate tube while offering a reduced head loss for the paint passing through the rod and while being easy to manufacture, the curved part is in the shape of a planar arc of circle, having a curve radius, the ratio of the diameter to the curve radius being less than 1.
US11325144B2 Trigger-type pump dispenser
[Object] To provide a trigger-type pump dispenser that makes it possible to prevent an out-of-nozzle squirting phenomenon that occurs at a final stage of sucking up of liquid out of a vessel into a cylinder.[Solution] A trigger-type pump dispenser A includes a handle structure 1, a nozzle base structure 2 attached to the handle structure 1, a trigger 3, a cylinder structure 4, a cap 5 by which the cylinder structure 4 is held down and attached to the mouth of a vessel, a piston structure 6 that slides inside the cylinder structure 4, an inverted-mortar-shaped lip 61 formed in the piston structure 6, a spring 7 that springs the piston structure 6, a valve case 8 attached to the nozzle base structure 2, a mortar-shaped valve seat 81 formed in the valve case 8, a leak valve 9, attached to a bottom part of the cylinder structure 4, that has a bulging portion 91 at a tip thereof, a first valve FV, and a second valve SV. A movement of the piston structure 6 from top dead center to bottom dead center causes liquid in the cylinder structure 4 to be discharged from a nozzle orifice N. The bulging portion 91 at the tip of the leak valve 9 is disposed to pass through the inverted-mortar-shaped lip 61. A through-hole diameter D1 of the mortar-shaped valve seat 81 of the valve case 8 is smaller than a nozzle orifice diameter D2.
US11325143B2 Powdering system
A powdering system, having a working configuration and a cleaning configuration and including a powder reservoir, including a supply chamber receiving powder; a sprayer, including a powder applicator, and a cleaning inlet, fluidly connected to the supply chamber such that, in the cleaning configuration, a cleaning air supply source can be connected to the cleaning inlet so as to circulate cleaning air in the supply chamber, wherein the powder reservoir includes a discharge opening, arranged through a wall of the supply chamber and opening into the supply chamber, and a movable plug, which is movable between a closing position, in the working configuration, and an open position, in the cleaning configuration, such that the circulation of cleaning air causes residual powder to be discharged through the discharge opening.
US11325140B2 Air turbine drive spindle
An air turbine drive spindle capable of suppressing a pressure increase inside a through hole is provided. A spindle includes a rotary shaft and an outer circumferential member (a housing assembly, a cover and a nozzle plate). The rotary shaft is provided with a through hole. The outer circumferential member includes a bearing sleeve configured to surround at least a portion of an outer circumferential surface of the rotary shaft. The outer circumferential member includes a gas supply portion and a gas exhaust hole. The spindle includes a second gas exhaust portion (a first gas exhaust hole and a first gas flow passage). The second gas exhaust portion is independent of the gas exhaust hole and continuous to outside from a gas exhaust space.
US11325135B1 Production of alternative supplemental cementitious material from uncured concrete made with Portland cement
A method and apparatus for producing liquified Alternative Supplemental Cementitious Material (ASCM) from an uncured concrete slurry. Uncured concrete slurry is received into a receiving hopper, diluted with water, and pumped upward through a slurry discharge conduit to an aggregate separator that screens the gravel and sand for separate discharge. The remaining ASCM entrained water flows into a holding tank. The ASCM settles to the lower portion of the holding tank. The holding tank stores the remaining water for re-use diluting uncured concrete slurry. The ASCM is liquified and moved towards the ASCM discharge port by an agitator system located in the bottom of the holding tank. From the discharge, a pump delivers the liquified ASCM through a conduit for discharge. The discharged ASCM can be used as a partial replacement for Ordinary Portland Cement and as an ingredient in flowable fills.
US11325133B1 Systems and methods for monitoring the roll diameter and shock loads in a milling apparatus
Systems and methods for monitoring the roll diameter and shock loads in a milling apparatus may include a frame, a pair of rolls including a movable first roll and a stationary second roll, roll supports configured to support the first roll on the frame in a movable manner and the second roll on the frame in a stationary manner, and a motor assembly configured to rotate at least one of the rolls. Embodiments of the systems may also include a wear sensing assembly configured to detect wear on at least one of the rolls of the pair of rolls. Embodiments of the systems may also include a shock sensing assembly configured to detect shock to at one of the rolls.
US11325132B2 Processing plant
The invention relates to a processing plant, in particular a rock crusher (10), having a filler unit (20,), which can be filled with a material to be crushed, wherein a screening unit (30) is arranged downstream of the filler unit (20) in the conveying direction or in the filler unit (20), which screening unit can be oscillated by means of a vibration exciter (38), wherein the screening unit (30) is used to feed a first part of the supplied material to a process unit, in particular a crusher unit (40) and another part of the supplied material is screened-out in the screening unit (30), wherein a flap (72) of a conveyor unit (70) adjustable about a swivel axis (74.1) is used in a bypass position to feed the screened-out part of the material either onto a conveyor device, in particular a crusher discharge conveyor (60), bypassing the process unit, in particular the crusher unit (40), or, in a conveying position, to discharge the screened-out part of the material from a working area of the processing plant by means of a conveyor device (50), wherein bearing segments (75.1) of a bearing (75) are coupled to opposite sides of the flap (72), which are rotatably installed on the conveyor unit (70). It is suggested that at least one detachable clamping segment (80.1, 80.2) is assigned to at least one of the bearing segments (75.1), which acts in a clamping manner on the assigned bearing segment (75.1) and secures the latter in a swivel position of the flap (72) relative to the conveyor unit (70), such that in the swivel position the flap (72) is secured against rotation relative to the conveyor unit (70).
US11325121B2 Analyte depletion for sensor equilibration
Methods include treating a portion of a sample composition to be tested for presence of an analyte by depleting or blocking the target analyte. The treated composition may be used to equilibrate an acoustic wave sensor prior to exposing the sensor to the untreated sample composition for analysis. By using the treated sample composition, in which the analyte is depleted or blocked, to equilibrate the sensor, the sensor may be equilibrated with a composition having a similar viscosity and non-specific binding characteristics to the untreated sample composition, which should result in improved accuracy when analyzing the analyte in the untreated sample composition.
US11325118B1 Device, kit and methods for creating platelet rich plasma
A device for extracting plasma from a fluid collection tube comprising: a tubular barrel having sidewall surrounding a lumen which extends between proximal and distal ends thereof, the tubular barrel forming a tip at a distal end; a barrel seal movingly seated within the lumen of the tubular barrel, the barrel seal closing and sealing the proximal end of the tubular barrel; a tube seal having a proximal end, a distal end, and a lumen extending therebetween, the proximal end having a frustoconical or chamfered face, the tube seal having an outer diameter sized to sealingly engage with an inner surface of the fluid collection tube, and an inner diameter sized to sealingly engage with an outer surface of the tip of the tubular barrel, the tube seal mounted on the tubular barrel such that the tip of the tubular barrel extends into the tube seal lumen.
US11325116B2 Tip set
Provided is a tip set used for a genetic testing device. The tip set includes a piercing tip breaking a lid portion of a reagent container filled with a reagent to open the reagent container and an injection tip injecting a sample solution containing a target gene nucleic acid into a microchip. The injection tip has a reservoir storing the sample solution in an internal space and an injection needle protruding from the reservoir, an opening the internal space to a side opposite to the injection needle is formed in the reservoir, and the piercing tip has a fitting portion fitted to the injection tip to connect the injection tip and the piercing tip.
US11325115B2 Visible-light response hybrid aerogel and preparation method and application thereof in waste gas processing
Visible-light response hybrid aerogel and a preparation method and application thereof in waste gas processing are disclosed. Dicyandiamide is taken as a precursor and is calcined in two times to prepare a carbon nitride nanosheet; the carbon nitride nanosheet is dispersed in water, silver metavanadate quantum dots are subjected to in-situ growth to prepare a silver metavanadate quantum dot/carbon nitride nanosheet composite material; the silver metavanadate quantum dot/carbon nitride nanosheet composite material and graphene oxide carry out hydrothermal reaction, and are then frozen and dried to prepare silver metavanadate quantum dot/carbon nitride nanosheet/graphene hybrid aerogel which is the visible-light response hybrid aerogel. The problems of large reduction dosage, serious secondary pollution, complexity in operation and the like generated when waste gas is processed by a traditional flue gas denitration technology are overcome.
US11325108B2 Hydroprocessing catalyst composition containing a heterocyclic polar compound, a method of making such a catalyst, and a process of using such catalyst
A composition that comprises a support material having incorporated therein a metal component and impregnated with an additive compound that is selected from the group of heterocyclic, polar compounds of the formula CxHnNyOz; wherein: x is an integer of at least 3; y is either 0, 1, 2, or 3; z is either 0, 1, 2, or 3; and n is the number of hydrogen atoms required to fill the remaining bonds with the carbon atoms of the molecule. The composition includes the support material that is impregnated with the additive compound and is useful in the hydroprocessing of hydrocarbon feedstocks, especially in the denitrogenation and desulfurization of distillate feedstocks to make ultra low sulfur diesel.
US11325090B1 Catalytic solar reactor
A catalytic solar reactor useful in chemical processes, more particularly, useful in endothermic chemical processes. The reactor comprises a reaction pathway defined by an exterior wall and an interior wall, the exterior wall comprising a solar radiation receiver capable of converting solar radiation into heat and transmitting the heat to the reaction pathway. Further, the reaction pathway has disposed therein, in alternating fashion, a plurality of catalytic elements and a plurality of heat transfer elements. Optionally, a supplementary heater, such as a conventional fossil fuel burner, is disposed in a plenum located within the interior of the reactor. The heater is employed as a supplemental source of heat, for example, when solar radiation is unavailable.
US11325088B2 Method of cleaning spent catalyst material
A method of cleaning spent catalyst material from a catalyst filter basket. The catalyst filter basket includes a central frame having a base ring and a generally cylindrical inner screen portion which extends upwardly from the base ring. A generally cylindrical outer screen assembly is releasably secured to the central frame by a quick release mechanism.
US11325087B2 Devices and methods for separating components
A method, system, and device for separating components is described. A vessel is provided. A first volume of a process liquid, containing a first component and a second component, is passed into an inner chamber. The piston retracts to a first position. The fluid inlet is closed. The piston is retracted to a second position, causing the first component and a first portion of the second component to flash to form a vapor stream while a second portion of the second component freezes to form a solid product stream. The fluid outlet is then opened. The piston is advanced to a third position that results in a third volume, smaller than the first volume, such that the vapor stream is expelled. The fluid outlet is closed. The piston is fully closed such that the solid product stream is pressed into and extruded through the solids outlet.
US11325085B2 Device for converting a linear movement in a stationary system into a rotational movement about a pivot axis in a system which rotates about a rotational axis
A conversion device for converting linear movement in a stationary system into rotary movement about a pivot axis in a system which rotates about an axis of rotation that is not identical or parallel to the pivot axis. The conversion device has a lift element and a lift device with which the lift element can be moved with translatory movement relative to the stationary system. The lift element has first and second lift element portions connected together by a rotary bearing so that the first lift element portion can be rotated relative to the second lift element portion about the axis of the rotary bearing. The first lift element portion is connected to the lift device and the second lift element portion is connected to the conversion device. The conversion device is connected to a shaft positioned on the pivot axis so that a linear movement of the second lift element portion is converted into a rotary movement of the shaft about the pivot axis.
US11325082B2 Blower unit for pneumatic mixers and apparatus for the pneumatic mixing of granules, powders and/or liquids comprising said blower unit
A blower unit for pneumatic mixers, comprising: a hollow element internally defining a duct, extending between an input section and an output section, for the passage of an air flow between said sections, wherein said input section can be connected to a source of pressurised air and said output section can be connected to a manifold of a pneumatic mixer; a shutter suitable to shut off said airflow through said output section in a controlled manner; an actuator connected to the shutter and configured to regulate the position of the shutter; the hollow element has a first end portion, at said output section, that can be reversibly coupled to a corresponding end portion of the manifold and wherein the blower unit further comprises first reversible connecting means to establish a reciprocal connection between the end portions.
US11325080B2 Mixer/vacuum coater
A mixer unit comprising a mixing chamber is disclosed. In one example, the mixing chamber comprises a de-agglomerator with a de-agglomeration shaft with de-agglomeration paddles, and a mixer with a mixer shaft with two or more mixing paddles that are arranged for mixing and impelling particles and powders in an upstream direction towards the de-agglomerator, whereby the de-agglomeration shaft is arranged above, and in parallel with said mixer shaft, so that all particles will be impelled towards the de-agglomerator, each time particles are lifted. A first portion of the mixing chamber may also have an inner profile adjacent and curved about an upper part of the de-agglomerator and is arranged to guide particles and powders impelled by the mixing paddles over the de-agglomeration shaft and into a liquid spray.
US11325075B2 Carbon capture membrane
There is provided a carbon capture mixed matrix membrane comprising: a polymeric support layer; and a carbon dioxide capture layer in contact with the polymeric support layer, the carbon dioxide capture layer comprising solid porous material with at least one carbon dioxide adsorption site, wherein the polymeric support layer comprises spatially ordered uniform sized pores. The polymeric support layer may be patterned by micro-molding, nanoimprinting, mold-based lithography or other suitable lithographic process. The carbon dioxide capture layer may comprise amine-functionalised material, metal-organic frameworks such as zeolite imidazolate framework 8 (ZIF-8) or copper benzene-1,3,5-tricarboxylate (Cu-BTC) which may or may not be amine modified. There is also provided a membrane module comprising at least one carbon capture mixed matrix membrane and a method of forming the carbon capture mixed matrix membrane.
US11325074B2 Porous membrane for water treatment and method for preparing the same
The present invention provides a porous membrane for water treatment, comprising: a high molecular weight polyethylene, a water-soluble polymer and an antioxidant, the high molecular weight polyethylene having an average molecular weight of 1.0×105 to 10.0×106 and a density of 0.940 to 0.976 g/cm3; wherein, the weight of the water-soluble polymer is 5 to 50 parts, the weight of the antioxidant is 0.1 to 10 parts, based on 100 parts of the weight of the high molecular weight polyethylene. The porous membrane for water treatment prepared by the present invention has a thickness of 5 to 30 μm, a pore size of 10 to 100 nm, a porosity of 20 to 60%, and a surface contact angle of 30° to 95°. The porous membrane according to the present invention has good durability, simple preparation process, and relatively thin thickness, a uniform pore size distribution and small pore size, good hydrophilicity, as well as good filtration and adsorption effect.
US11325071B2 Catalytic converter for treating exhaust gases
The invention relates to a catalytic converter for treating exhaust gases of an internal combustion engine, having a housing through which an exhaust gas may flow and which has an inflow side and an outflow side, wherein, in the housing, there is formed a plurality of flow channels (4, 13) which is flowed through along a main throughflow direction from the inflow side to the outflow side, wherein, in the housing, there is arranged at least one pipeline (5, 12) which is flowed through by a fluid which is independent of the exhaust gas that is caused to flow through the flow channels (4, 13).
US11325043B2 Utilizing multiple input sources for generating gameplay locations
The present concepts relate to placing gameplay locations in the real world, where gameplay elements can be generated at the gameplay locations. One example categorizes types of physical elements described in geolocation data, and determines scores for the physical elements based on the categorizations. Gameplay locations can then be utilized according to the scores, and the scores can be continuously refined through user or moderator interaction with gameplay elements that may be generated at the gameplay locations.
US11325036B2 Interface display method and apparatus, electronic device, and computer-readable storage medium
An interface display update method is performed by an electronic device, including: displaying a virtual item currently controlled by a virtual object in a virtual scene; detecting a perspective rotation operation associated with the virtual object; obtaining a target rotation angle, a first rotation speed of a perspective of the virtual object, and a second rotation speed of the virtual item according to the perspective rotation operation, the second rotation speed being less than the first rotation speed; and updating the virtual scene, based on the target rotation angle, the first rotation speed of the perspective of the virtual object, and the second rotation speed of the virtual item, using a target animation in which the virtual scene changes in accordance with the perspective rotation operation, the target animation visualizing an effect that rotation of the virtual item lags behind rotation of the perspective of the virtual object.
US11325032B2 Virtual reality image playing device and method for playing multiple virtual reality images by using one streaming image
The present invention provides a virtual reality image playing device, the device comprising: a streaming image input unit for receiving, through streaming, one streaming image including multiple virtual reality images captured in different directions at an identical time and at an identical point; a streaming time operation unit for adding a play position of a currently playing virtual reality image to a reference time of a virtual reality image to be newly played; and an image playing unit for playing a streaming image, which has been streamed, on a display device. When virtual reality images captured in different directions are to be played as a gaze of a user changes, the virtual reality image playing device plays multiple virtual reality images by using one streaming image by performing a streaming time jump of a streaming image, using a reference time at which an individual virtual reality image starts.
US11325019B2 Pole handle and pole comprising said pole handle
Pole handle, for alpine ski poles or cross-country ski poles, with a handle body and with a hook for fastening a hand holding device. A displaceable latching structure is arranged in the region of the hook so that an eye-shaped device which is pushed in from above and is provided on the hand holding device is fixed in a self-locking manner. The hook is arranged on the stick handle on the hand side in the upper region. A holding mandrel, which is set off from the handle body to the hand side, forms an insertion slot. The latching structure includes a retaining lug which defines a region, restricted against a force, for the eye-shaped device. An upper region of the holding mandrel or the entire holding mandrel, viewed in the running direction, can be deflected laterally on both sides against a restoring force.
US11325018B2 Heel unit for a downhill or a combined downhill and alpine touring ski binding
A heel unit for a downhill or a combined downhill and alpine touring ski binding has a vertical-release functional group with a tensioning device with a first spring assembly for holding a ski boot downhill, and a horizontal-release functional group with a base plate to be positioned on the ski and a slide that deflects laterally opposing the ski longitudinal direction against the force of a second spring assembly, on which the vertical-release functional group is arranged, as well as with a compression spring assembly acting on the horizontal-release functional group. The vertical-release functional group rotates on the horizontal-release functional group around an axis running vertically towards the top of the ski or towards the vertical, such that, after a limited lateral deflection of the slide, the vertical-release functional group rotates against the force of the second spring assembly to release of the ski boot into the respective lateral-release direction.
US11325016B1 Pneumatic ball launcher
A pneumatic ball launcher includes a tube, a ball pathway unit, a push unit, a holding unit, an airway unit and a pneumatic unit. The ball pathway unit is used for connecting one end of the tube and wrapping part of a ball channel of the tube. The push unit includes a push bar, a slide base, a first driver and a second driver. The holding unit, detachably connected with the push unit, is used for holding the ball pushed by the push bar. The airway unit is connected with the holding unit. The pneumatic unit includes a valve mechanism, a pneumatic cylinder and a gas tank. When the valve mechanism opens to allow the gas tank to discharge into the holding unit via the airway unit, the ball held by the holding unit would be ejected out of the tube.
US11325011B2 Golf ball manufacturing method
A method of manufacturing golf balls having a core and a cover of at least one layer encasing the core includes the steps of producing a core by molding and vulcanizing a rubber composition containing (A) a base rubber, (B) an α,β-unsaturated carboxylic acid and/or a metal salt thereof, and (C) an organic peroxide; and heat-treating the core for 1 to 24 hours at between 175 and 300° C. Golf balls which undergo little energy loss and have a high initial velocity can be obtained by this method.
US11325008B2 Golf balls having covers made with thermoplastic polyurethane and polydimethylsiloxane blend compositions
Golf balls having covers made of thermoplastic polyurethane compositions are provided. Multi-piece golf balls can be made. In one embodiment, the outer cover layer is formed from a composition comprising a thermoplastic polyurethane and polydimethylsiloxane compound. Functionalized polydimethylsiloxane compounds also can be used to treat thermoplastic polyurethane golf ball covers. The cover composition and surface coatings can further include catalysts, ultraviolet (UV)-light stabilizers, and other additives. The coating methods have many benefits and the finished balls with thermoplastic polyurethane covers have good physical properties.
US11325006B2 Surfing glove
Enhanced surfing by means of waterproof gloves which provide lifting pads spanning the width of the palm from the base of the thumb and terminating near the pinky, or also extending across the upper palm finger pads if desirable, while secured tightly at the wrist. The padding is contoured and rises to prescribed height starting at the base of the wrist, rising to the maximum height near the base of the palm, and then returning to ‘level’ with the hand inside the palm. Similarly, narrower finger pads will follow a similar contour but will have less height than the palm pad. The padding provides a resilient, rebound boost to aid surfers in quickly rising to their feet while simultaneously creating more clearance between a surfer's torso and board to allow for a heightened swing arch to create forward distance for initial foot positioning and added takeoff momentum.
US11325001B2 Immersive and reactive game play range, system and process
The invention generally relates to an immersive and reactive game play system and process having a dynamic, interactive range surface and/or an end-of-range display that provide for a partially simulated environment with a shared field of play for the activity that allows for an immersive but shared view of each user and the other users, and further expands participation by combining the advantages of simulated display with a physical field of play. The immersive and reactive game play system and process is configured to simultaneously display flight paths of multiple balls struck from a multi-level, multi-bay golf and entertainment facility. The interactive range surface provides a visual, auditory and/or physical effect to a golf ball traveling over or landing on the range surface, and the end-of-range display is configured to display the continued flight path of the golf ball.
US11325000B2 Wearable device systems and methods for guiding physical movements
A system includes wearable devices positioned on a subject in different locations. Each wearable device includes motion sensors that measure the subject's movement in three dimensions. The motion sensors generate raw sensory data as the subject performs a physical movement. A data filter is selected based on a condition of the subject and a designated movement corresponding to the physical movement, and used to convert the raw sensory data into formatted data. A level of compliance of the physical movement with a movement model for the designated movement is determined by applying comparative modeling techniques to the formatted data and the movement model. Real-time feedback is delivered dynamically to the subject by the wearable devices during the performance of the physical movement based on the level of compliance. The movement model can be generated, and the comparative modeling techniques can be selected, based on the condition of the subject.
US11324997B2 Abdominal and core exerciser device
There is provided a plank exercise device including a support portion adapted to receive arms or hands of a person and adapted to receive a display device, a destabilizer connected to the support portion, and a stationary base adapted to hold the destabilizer.
US11324980B2 Sprinkler head
A sprinkler head includes a body having a nozzle to be connected to a water supply pipe, the nozzle being provided inside the body; a valve that closes the nozzle in normal times; a pair of frames extending from the body in a direction of water discharge from the nozzle; a deflector provided at a distal end of a part where distal ends of the frames are coupled to each other on a center axis A of the nozzle; and a heat sensitive disassembling unit provided between the valve and the deflector. A spring that is bent in a W shape has two ends engaged with the pair of frames, and the heat sensitive disassembling unit is fitted in a bent portion provided between the two ends and of the spring.
US11324979B2 Fire extinguisher
In order to provide a portable fire extinguisher suitable for first-aid fire extinguishing, the fire extinguisher, using as the fire-extinguishing agent inert gas, etc. not limited in the object to be extinguished and the method of use due to toxicity to human body and making easy to maintain the necessary concentration of the fire-extinguishing agent, thus securing the effective fire-extinguishing effect, has the fire-extinguishing agent storage container to which the nozzle portion to discharge the fire-extinguishing agent is connected and made portable so as to be able to discharge the fire-extinguishing agent toward the object to be extinguished, and the nitrogen gas is stored in the fire-extinguishing agent storage container and at the outlet portion of the flow route of the fire-extinguishing agent formed in the nozzle portion, a metallic porous member in installed.
US11324978B2 Fire-fighting fluid storage apparatus of battery pack
The present application is provided with a fluid storage apparatus of a battery pack, including: a box, where the box has an inner cavity; a partition member, where the partition member is located in the inner cavity of the box, and the partition member divides the box into a fluid storage portion and a gas storage portion. The fluid storage portion is used to store spraying liquid and the fluid storage portion has a fluid outlet; the gas storage portion is used to store gas and the gas storage portion has a fluid inlet. And the partition member is configured to move toward the fluid outlet under the action of compressed gas in the gas storage portion.
US11324972B2 Radiotherapeutic device and laser verification apparatus thereof
The present disclosure discloses a laser verification apparatus employed in a radiotherapeutic device which comprises a plurality of radioactive sources, a collimator comprising a plurality of collimating holes, and a couch. The radioactive sources are capable of aligning in respect to the collimating holes respectively. The laser verification apparatus comprises: a positioning plate, fixed on the multi-source radiotherapy equipment and arranged between the radiation sources and the collimators; a movable plate, arranged on and movable relative to the positioning plate, and provided with a plurality of first mounting holes and a plurality of second mounting holes, which are arranged one by one, alternately, the movable plate is configured to switch the plurality of first mounting holes or the plurality of second mounting holes to positions corresponding to the plurality of collimators; a plurality of laser emitters respectively received in the second mounting holes, and an acquisition analyzer arranged on the couch and configured to acquire the light beams emitted by the laser emitters and perform data analysis.
US11324967B2 Therapeutic electron radiator for cancer treatment
A method that produces high energy charged particles that may be used to destroy cancer cells contained in cancerous tissues. The device uses electronic neutron generators to produce neutrons with energies that have a high probability to interact with a therapeutic source comprised of a reactive material with an outer layer of a material having a high atomic number such as Platinum or Gold. The reaction produces high energy electrons, and in some cases other charged particles with relatively short half-lives, which can destroy the cancerous cells, without seriously damaging the surrounding healthy tissue.
US11324966B2 Delivery system for intensity modulated high dose rate brachytherapy with intermediate energy brachytherapy isotopes
A delivery system and method for radiation shielded brachytherapy has a drive assembly, and a plurality of shield assemblies, pivotally mounted to the drive assembly, each having a tubular body defining an outer surface and a bore longitudinally extending between opposite ends of the tubular body. Each of the shield assemblies has radiation shielding material extending about a circumferential portion of the tubular body and disposed between the outer surface and the cavity. An interlocking system is operatively mounted to the rotating assembly, and engages a group of the plurality of shield assemblies. The interlocking system is configured for transmitting a rotational input received from a driving mechanism to the group of shield assemblies, for synchronously rotating each shield assembly of the group about their respective longitudinal axis.
US11324965B2 Non-invasive energy upconversion methods and systems
Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength λ1, to generate a second wavelength λ2 of radiation having a higher energy than the first wavelength λ1. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.
US11324964B2 Apparatus for dermatological treatment
The present invention relates to a light emitting device for providing dermatological treatment. The present invention comprises a housing structure for housing a light emitting source, a fan and a duct. The light emitting source is arranged to emit light energy to external of the device and the fan is configured for directing air heated by operation of the light emitting source into the duct. The duct is arranged to direct heated air in an airstream pathway from an outlet port of a distal end of the duct and through an aperture in the housing structure where the housing structure and the duct are relatively arranged such that no part of the housing structure extends into the air stream pathway in order to minimise heat exchange from the heated air to the housing structure.
US11324963B2 Brain stimulation treatment in depression
Provided herein are, for example, systems and methods of diagnosing and treating depression, in which a transcranial magnetic stimulation (TMS) therapy is administered to a subject in need thereof and measuring a TMS evoked response in the subject, are provided. The systems and methods allow tailoring or optimizing of a treatment protocol for maximal individual benefit, thereby providing an individualized and optimized treatment protocol for psychiatric disorders such as depression.
US11324960B2 Permission-based control of interfacing components with a medical device
Disclosed are embodiments directed to security methods applied to connections between components in a distributed (networked) system including medical and non-medical devices, providing secure authentication, authorization, patient and device data transfer, and patient data association and privacy for components of the system.
US11324955B2 Implantable hub and satellite system for neural recording and stimulation
The systems and methods described herein include an external base station with a tethered transceiver, an implanted hub that includes power, telemetry, and processing electronics, and a plurality of implanted satellite that contain reconfigurable front-end electronics for interfacing with electrodes. The system can operate in different modes. In a first mode, called a base boost mode, the external base station is used for closed-loop control of stimulation therapies. In a second, autonomous mode, closed-loop control is performed in the hub without direct influence from the base station. In a third mode, streams of neural data are transmitted to an offline processor for offline analysis.
US11324951B2 Electrical treatment device, control method, and treatment system
An electrical treatment device (200) includes a remaining power detection unit (302) that detects a remaining battery power of the electrical treatment device (200); a treatment content setting unit (306) that sets a treatment content; an impedance measurement unit (304) that measures a bioelectrical impedance of a site on a body of a user by using electrodes that come into contact with the site; a treatment execution unit (312) that performs treatment of the site by controlling a voltage waveform applied to the electrodes; and a determination unit (310) that determines whether treatment in accordance with the treatment content can be executed up until a treatment time elapses on the basis of a current remaining battery power and a power consumption calculated from the bioelectrical impedance and the voltage waveform. When treatment in accordance with the treatment content cannot be executed up until the treatment time elapses, the treatment execution unit (312) modifies a voltage waveform corresponding to the treatment content currently set so that treatment can be executed up until the treatment time elapses, and outputs the modified voltage waveform.
US11324946B2 Systems and methods for the treatment of oral and systemic maladies in animals using electrical current
Systems and methods for the concurrent treatment of multiple oral diseases and defects while promoting general oral hygiene utilizing electricity are provided for non-human animals. Electrodes are used to deliver an electrical current to the gingival tissues of a mouth in order to achieve a number of therapeutic, prophylactic, and regenerative benefits. These benefits include killing oral microbes, increasing oral vasodilation, reducing oral biofilm, improving oral blood circulation, reversing oral bone resorption, promoting oral osteogenesis, treating gum recession, and fostering gingival regeneration. Other benefits include the treatment of gingivitis, periodontitis, and oral malodor, and other systemic diseases correlated with oral pathogens.
US11324936B2 System and method for delivering fluid internally of a patient's body
A fluid distribution system for delivering fluid internally of a body comprises a hollow needle and an implantable access port. The needle has a tip with a predetermined shape. The access port includes (a) a housing that includes at least two fluid outlets, (b) a septum received in the housing, and (c) a valve member rotatable in the housing. The valve member includes valve fluid inlet and outlet openings and a valve inlet passage extending from the inlet opening to the outlet opening. The valve inlet passage has a shape complementary to the shape of the needle tip. The valve member is rotatable into (i) a first position in which the valve fluid outlet opening communicates with a first housing fluid outlet and (ii) a second position in which the valve fluid outlet opening communicates with a second housing fluid outlet.
US11324933B2 Apparatus for minimally-invasive prevention and treatment of hydrocephalus and method for use of same
An apparatus for minimally-invasive, including non-invasive, prevention and/or treatment of hydrocephalus and method for use of the same are disclosed. In one embodiment of the apparatus, a housing is sized for superjacent contact with a skull having a fontanel. Within the housing, a compartment includes a pressure applicator, such as a fluid-filled bladder, under the control of a pressure regulator. The pressure applicator is configured to selectively apply an external pressure to the fontanel. The compartment includes a pressure sensor configured to measure intracranial pulse pressure of the fontanel. Further, in one embodiment, the apparatus can cause pulse pressure modulation by adjusting the intracranial pulse pressure via the pressure applicator. This enables a non-invasive measurement of the pulse pressure and modulation thereof in infants, for example.
US11324926B2 Introducer needle with notches for improved flashback
A catheter system may include a catheter adapter, a catheter extending distally from the catheter adapter, an introducer needle extending through the catheter, a flash chamber in fluid communication with a needle lumen of the introducer needle, and a seal element. The introducer needle may include a wall defining the needle lumen, a first notch formed through the wall, and a second notch formed through the wall. The seal element may be proximal to the first notch and the second notch and within the catheter between an outer surface of the introducer needle and an inner surface of the catheter. The seal element may prevent priming fluid from travelling distal to the seal element. The seal element in conjunction with the first notch, the second notch, and the flash chamber may facilitate pressure-driven blood flow into the catheter for detection of flashback and transfixing when priming occurs prior to insertion into vasculature.
US11324923B2 Helical balloon catheter
Methods and devices described for improved catheters including those having a deflectable section to allow for expansion while maintaining flow through a vessel.
US11324912B2 Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO2-to-NO reactor cartridge and/or a break-through of NO2, and providing an indication of the remaining useful life and/or break-through.
US11324911B2 Flow mixers for respiratory therapy systems
A flow of gases in a respiratory therapy system can be conditioned to achieve more consistent output from sensors configured to sense a characteristic of the flow. The flow can be mixed by imparting a tangential, rotary, helical, or swirling motion to the flow of gases. The mixing can occur upstream of the sensors. The flow can be segregated into smaller compartments to reduce turbulence in a region of the sensors.
US11324909B2 Ventilation mask
Disclosed is a nasal ventilation mask having separate ports to monitor end-tidal CO2 expulsion integrated into the mask in order to monitor end-tidal CO2 expelled nasally or orally. Also disclosed is a CPR mask for nose-to-mouth and/or mouth-to-mouth resuscitation, having a body shaped to cover the nose and/or mouth of a victim, the mask including a CO2 absorber for eliminating at least in part rescuer's exhaled CO2 delivered to the victim.
US11324908B2 Collapsible conduit, patient interface and headgear connector
A conduit with a collapsible portion, and a nasal interface for providing a flow of gases to a user, is described. The interface comprises a manifold and at least one nasal prong or an outlet extending from the manifold to be received by a user's nare. A side member extends from each side of the manifold, each side member comprising a collapsible portion comprising a lumen. In an open configuration the lumen remains open and in a closed configuration the collapsible portion is pinched or flattened to occlude or substantially occlude the lumen. At least one of the side members is a conduit for a flow of gases from an inlet of the patient interface to the manifold.
US11324894B2 Assembly for a drug delivery device and drug delivery device
An assembly for a drug delivery device comprises a housing, a dose member which is displaceable in a proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position. The clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose.
US11324892B2 Electronic module and drug delivery device
The invention relates to an electronic module for recording information of a drug delivery device, the electronic module comprising at least one connector, wherein at least one connector is adapted to be connected to a port of the drug delivery device and wherein at least one connector is adapted to be connected to a port of a computer. Furthermore, the invention relates to a drug delivery device, comprising a port for connecting to the connector of the electronic module.
US11324889B2 Compensation for missing readings from a glucose monitor in an automated insulin delivery system
Exemplary embodiments may address the problem of missing blood glucose concentration readings from a glucose monitor that transmits blood glucose concentration readings over a wireless connection due to problems with the wireless connection. In the exemplary embodiments, an automated insulin delivery (AID) device uses an estimate in place of a missing blood glucose concentration reading in determining a predicted future blood glucose concentration reading for a user. Thus, the AID device is able to operate normally in generating insulin delivery settings despite not receiving a current blood glucose concentration reading for a current cycle. There is no need to suspend delivery of insulin to the user due to the missing blood glucose concentration reading.
US11324887B2 Reporting syringe
A reporting syringe, including a barrel in fluid communication with a needle connected with a first end of the barrel, a piston including a plunger, the piston positioned within a second end of the barrel and the plunger having a fluid-tight interaction with an interior of the barrel, and a microprocessor in electronic communication with a switch and a wireless module, the microprocessor configured to send an administration completion data from the wireless module after triggering the switch.
US11324886B2 Medical device with automated modality switching
A medical device such as an infusion system detects that an accessory has been coupled to the device. The medical device initially operates in a first mode of operation. The medical device, in response to the detecting, associates the accessory with a different mode of operation for the medical device that requires changes to at least one of the operating parameters for the infusion system or elements within a graphical user interface. The medical device then automatically changes the mode of operation from the first mode of operation to the associated different mode of operation to reflect the coupling of the accessory to the infusion system. Related apparatus, systems, techniques and articles are also described.
US11324885B2 Infusion device and method for administering a medical fluid to a patient
An infusion device (1) for administering a medical fluid to a patient (P) comprises a pump mechanism (11) for administering a medical fluid to a patient (P) through a line set (3), a sensor device (14) for measuring a measurement value indicative of a pressure in the line set (3), and a processor device (15) configured to automatically set, in an initial phase, a threshold value (15) to a value determined based on at least a mechanical characteristic of the line set (3) and/or the pump mechanism (11) and to determine, in an operational phase, whether an occlusion condition in the line set (3) is present based on the measurement value and the threshold value (Pthres) —Herein, the processor device (15) is configured to adjust the threshold value (Pthres) if in the operational phase a pressure variation condition in the line set (3) different than an occlusion condition is detected by the processor device (15). In this way an infusion device is provided which may be able to reliably detect an occlusion condition even in case of multiple infusion devices acting on a line set in a multiline infusion.
US11324882B2 Protective case for an auto-injector
The application describes a protective case for an auto-injector. The medicament contained within these auto-injectors can be susceptible to degradation due to exposure to extreme temperatures and light. Thus, one embodiment of the protective case reduces the rate of heat transfer between the internal storage compartment of the case and the external atmosphere by including particularly configured vacuum chambers. Additionally, as auto-injectors become smaller, portability can be desirable. Thus, another embodiment of the protective case includes low-profile cases that allow the user to keep the auto-injector with them, e.g., by attaching the case to a common everyday item.
US11324867B2 Blood circuit pressure graphical element for medical treatment user interfaces
Graphical user interfaces for use with extracorporeal blood treatment systems may include a blood circuit pressure graphical element. The blood circuit pressure graphical element may include a venous portion and an arterial portion. The venous portion may depict, or include, a presently-monitored venous blood circuit pressure value and a graphical representation of previously-monitored venous blood circuit pressure values, and the arterial portion may depict, or include, a presently-monitored arterial blood circuit pressure value and a graphical representation of previously-monitored arterial blood circuit pressure values.
US11324862B2 Endoluminal device
An endoluminal device includes a composite yarn with a polymer yarn and an alloy wire. The polymer yarn includes a biodegradable polymer, and the alloy wire includes a biocompatible alloy. An endoluminal device can include a plurality of polymer yarns and at least one alloy wire, in which the polymer yarns include a biodegradable polymer, and the least one alloy wire includes a biocompatible alloy. A surgical system or kit includes an endoluminal device and a delivery instrument.
US11324859B2 Carrier composition for bone substitute materials
The present invention relates to a carrier composition for particulate and granular bone substitute materials which is a hydrogel comprising a mixture of ethylene oxide (EO)-propylene oxide (PO) block copolymers and silica nanoparticles embedded therein. The present invention further relates to a bone substitute material containing osteoconductive and/or osteoinductive particles or granules in addition to the novel carrier composition. Processes for producing the novel carrier composition and the novel bone substitute material are likewise provided in the context of the invention.
US11324855B2 Cell-free combination, hydrogel-like material or hydrogel and use of same
A cell-free combination for use in the controlled, especially decelerated or retarded, release of active ingredient and/or in the production of a formulation in hydrogel form, especially depot formulation in hydrogel form, and/or as a formulation in hydrogel form, especially depot formulation in hydrogel form, and/or for the coating of a medical product, especially implant, preferably with a formulation in hydrogel form, especially depot formulation in hydrogel form, wherein the cell-free combination comprises a first component and a second component, the first component comprising crosslinkable albumin and the second component comprising a crosslinking agent for the albumin. Additionally, a hydrogel-forming material or hydrogel, to a kit or multicomponent system, to a medical product or a pharmaceutical formulation, to a discharge device, and to uses of the cell-free combination and of the hydrogel-forming material or hydrogel.
US11324850B2 Exhaled air purification unit and system for indoor multi-person venues or environments
An air purification unit and/or system for an environment with multiple seated individuals, including an air collector and air purification chamber, to be used independently from or in conjunction with the environment's air handling system.
US11324846B2 Sanitization device for groceries or other objects
A sanitizer using radiation comprises a hollow housing with an aperture, the housing being generally opaque to the radiation utilized. Mounted to the interior surfaces of the housing are radiation sources that produce radiation when powered. In operation, multiple objects to be sanitized are placed within the interior and the radiation sources powered, thereby sanitizing by radiation any pathogens present on the objects be irradiated. An easily adjustable shelving system that is substantially non-opaque to the radiation utilized, such as wire shelving with minimal opaque surfaces, may be used to support the objects to be sanitized. Depending on size, the portable box allows for multiple objects to be sanitized at the same time. The sanitizer in certain embodiments includes a plurality of UVC radiation sources mounted in the interior of the housing so as to surround the object to be sanitized on multiple sides.
US11324844B2 UV sterilization device for board-type kitchenware
A UV sterilization device for a board-type kitchenware includes a base with a driving member being received therein and defining a first motor, a left work-board, a right work-board, with a receiving room being formed between the left and right work-boards for receiving the board-type kitchenware therein, and a UV sterilization module connected to the first motor, longitudinally arranged on the inside of the left and right work-boards and horizontally sliding relative to the left and right work-boards. The first motor is configured to drive the UV sterilization module to slide so as to sterilize the board-type kitchenware received in the receiving room. The present structure not only can have a good disinfection and bactericidal effect on the harmful bacteria, pathogenic bacteria and molds left on the kitchenware with a minimize disinfection time, but also can reciprocate sterilization of the board-type kitchenware to achieve all-round sterilization by simple operation.
US11324843B2 Lighting device that deactivates dangerous pathogens while providing visually appealing light
A lighting device configured to deactivate pathogens in an environment. The lighting device includes a housing, means for mounting the housing to a surface in the environment, one or more first light-emitting elements arranged in the housing and configured to each produce disinfecting light having a wavelength in a first range of wavelengths, and one or more second light-emitting elements arranged in the housing and configured to each produce disinfecting light having a wavelength in a second range of wavelengths different from the first range of wavelengths. The disinfecting light produced by the first light-emitting elements and the disinfecting light produced by the second light-emitting elements mix to form a combined light, the combined light being visible light other than white light.
US11324842B2 Light irradiation device
The light irradiation device includes a light source supporter having a tubular shape is closed on a side of one end, a plurality of light-emitting elements placed on an outer wall surface of the light source supporter, a tubular body extending inside the light source supporter in an axial direction of the light source supporter, a first flow channel formed between the tubular body and the light source supporter and having an annular shape when viewed from the axial direction; and a second flow channel formed inside the tubular body, wherein the first flow channel and the second flow channel communicate with each other on a side of one end of the light source supporter, and the tubular body contains a material having a thermal conductivity lower than a thermal conductivity of a material constituting an outer wall of the first flow channel.
US11324841B2 Metal oxide nanoparticle-based magnetic resonance imaging contrast agent with a central cavity
The present invention relates to a magnetic resonance imaging (MRI) contrast agent, particularly an MRI contrast agent derived from nanoparticle that is porous first metal-doped second metal oxide nanoparticle with a central cavity, and a method for producing the same. The MEI contrast agent made in accordance with the present invention can be used not only as a drug-delivery agent for therapy but also as an MRI contrast agent for diagnosis.
US11324840B2 Magnetic microstructures for magnetic resonance imaging
The present invention relates to a magnetic resonance structure with a cavity or a reserved space that provides contrast and the additional ability to frequency-shift the spectral signature of the NMR-susceptible nuclei such as water protons by a discrete and controllable characteristic frequency shift that is unique to each MRS design. The invention also relates to nearly uniform solid magnetic resonance T2* contrast agents that have a significantly higher magnetic moment compared to similarly-sized existing MRI contrast agents.
US11324837B2 Hybrid membrane-coated nanoparticle composites and methods of making and using the same
Disclosed herein are embodiments of nanoparticle composites that comprise covalently coupled stabilizing agent molecules that improve stability of the nanoparticle composites and allow for tight packing of lipids and/or membranes. The nanoparticle composites can further comprise inhibition inhibitors and/or lipid components that interact to form a hybrid lipid bilayer membrane around the nanoparticle core. The nanoparticle composites can be coupled to drugs, targeting moieties, and imaging moieties. The nanoparticle composites can be used for in vivo drug deliver, disease diagnosis/treatment, and imaging.
US11324835B2 Nucleic acid-loaded unit polyion complex
A unit-type polyion complex for use in delivering nucleic acid to a target site in a patient includes one or more molecules of a block copolymer having a poly(ethylene glycol) segment and a cationic poly(amino acid) segment and one or more molecules of a nucleic acid. A total quantity of positive charges derived from side chains of the cationic poly(amino acid) segment of the block copolymer in the unit-type polyion complex is not offset by a total quantity of negative charges derived from the nucleic acid. Furthermore, the nucleic acid has a strand length of 10-50 bases, the molecular weight of the poly(ethylene glycol) segment is 40×103 or more, and the block copolymer has a binding constant (Ka) for the nucleic acid of 3.0×105 or more.
US11324827B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor
Disclosed are a multifunctionalized polyethylene glycol derivative and a preparation method therefor. The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n1, n2, n3, and n4 respectively are the degrees of polymerization of the branch chains, U1 and U2 are trivalent branching groups connecting the core LPEG to two of the PEG branch chains, F1 and F2 contain a functional group or a protected form R01 thereof and may or may not contain a branched group G, correspondingly, the number of R01 is one or more, F1 and F2 are either identical or different, any one linking group in the molecule or any linking group formed with an adjacent heteroatom group can either remain stable or be degraded, and any one PEG segment in the molecule is discretely polydispersed or monodispersed. The multifunctional polyethylene glycol is flexible and diverse in terms of branch structures and the lengths of branching arms, has various parameters and performance indicators that are adjustable and easy to control, and has a broad applicability.
US11324826B2 Multifunctional treatment and diagnostic compositions and methods
Multifunctional compositions and methods are provided for therapeutic treatment of bacteria and cancers and for fluorescence diagnosis. Systems generate in situ reactive oxygen species such as singlet oxygen (1O2), hydroxyl radical (OH) and Juglone, and other chemotherapeutic agents. Methods provided selectively produce greater amounts of one reactive oxygen species over others. Variations are effective in aerobic, anaerobic or H2O2 rich environments and in presence of, or absence of, light. In H2O2 rich environment in absence of light, variations decompose H2O2 into O2 gas to remove excess H2O2 for elimination of hypoxic environment. Variations are formed of porphyrins, naphthalene derivatives, and metal ions, for illustration, free base tetrakis Ar substituted porphyrine core without metal or halide substitution but having hydroxyphenyl and alkyl pyridyl substituents at meso positions combined with dihydroxynaphthalene and +3 hydrated metal ions.
US11324820B2 Methods for the treatment of subjects having a hepatitis b virus (HBV) infection
The present invention provides methods for the treatment of a subject having a Hepatitis B virus (HBV) infection, e.g., a chronic HBV infection, using a combination of an RNAi agent that targets HBV and an HBV vaccine. It is disclosed a RNAi agent and an HBV vaccine for use in treatment of HBV infection, comprising sequentially administering to the subject having an HBV infection: a) an RNAi agent that inhibits expression of at least three HBV transcripts, wherein the RNAi agent forms a double stranded region; b) a protein-based vaccine comprising a first HBV core antigen (HBcAg) polypeptide, and a first HBV surface antigen (HBsAg) polypeptide; and c) a nucleic acid-based vaccine comprising an expression vector construct encoding a second HBcAg polypeptide, and/or a second HBsAg polypeptide, wherein the second HBcAg polypeptide, and/or the second HBsAg polypeptide, shares at least one epitope with at least one of the first HBcAg polypeptide, and/or the first HBsAg polypeptide.
US11324814B2 Live attenuated oral vaccine against ETEC and typhoid fever
Disclosed is the attenuated Salmonella typhi vaccine Ty21a utilized as a vector for Shigella and/or enterotoxogenic E. coli genes stably integrated in the Ty21a chromosome. These genes include a heterologous Shigella sonnei O-antigen biosynthetic gene region that comprises the wzz gene and expresses Shigella sonnei form 1 O-antigen, as well as a heterologous acid resistance biosynthetic gene system comprising a YbaS gene, which enables increased stability of the Ty21a vector at pH 2.5 relative to Ty21a without the integrated acid resistance biosynthetic gene system.
US11324813B2 Indoleamine 2,3-dioxygenase based immunotherapy
The present invention relates to the field of prophylaxis and therapy of cancer. In particular there is provided a protein Indoleamine 2,3-dioxygenase (IDO) or peptide fragments here of that are capable of eliciting anti-cancer immune responses. Specifically, the invention relates to the use of IDO or peptides derived here from or IDO specific T-cells for treatment of cancer. The invention thus relates to an anti-cancer vaccine which optionally may be used in combination with other immunotherapies and to IDO specific T-cells adoptively transferred or induced in vivo by vaccination as a treatment of cancer. It is an aspect of the invention that the medicaments herein provided may be used in combination with cancer chemotherapy treatment. A further aspect relates to the prophylaxis and therapy of infections by the same means as described above.The use of IDO and immunogenic peptide fragments hereof in cancer and infection treatment, diagnosis and prognosis is also provided.
US11324812B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11324803B2 Methods and compositions for treatment of Gaucher Disease via modulation of C5a receptor
Disclosed are compositions and methods for the reduction of C5a mediated immune inflammation. The methods, in various aspects, may include the step of administering a C5aR antagonist to a subject in need of such treatment. In one aspect, the subject in need may have a lysosomal acid storage disease. Therapeutic kits and articles of manufacture are also disclosed.
US11324799B2 Gap junction intercellular communication modulators and their use for the treatment of diabetic eye disease
The use of gap junction intercellular communication (GJIC) modulators in the treatment or prevention of diabetic eye disease is disclosed, and more particularly to their use for the treatment or prevention of early stage diabetic retinopathy and diabetic macular edema by inhibiting apoptosis of retinal endothelial cells and inhibiting pericyte loss.
US11324798B2 Materials and methods for treatment of inflammation
The subject invention pertains to peptides and salts thereof that are useful as anti-inflammatory agents and to compositions containing such peptides and salts as active ingredients. Specifically exemplified herein are endomorphin-1 peptide (EM-1), analogs and salts thereof, and uses for modulation of calcitonin gene-related peptide (CGRP) production and/or substance P (SP) and for treatment of inflammation, particularly neurogenic inflammation.
US11324796B2 Method for regulating lipolysis and fatty acid oxidative metabolism
Provided are a method for promoting the lipolysis and fatty acid oxidative metabolism in mammals or cells derived from mammals, a method for downregulating the fat content and the weight of a mammalian body, as well as a method for increasing the intracellular cAMP concentration, increasing the phosphorylation degree and the activity of the hormone-sensitive esterase HSL, enhancing the transcription activity of PPAR alpha and increasing the activities of enzymes involved in a fatty acid beta oxidation process. By simulating the expression of a protein corresponding to a gene responsible for the phosphorylation of the Fas-associated death domain protein, or treating and acting on mammals or cells derived from mammals with a material that can increase the phosphorylation degree of the Fas-associated death domain protein, said methods increases the phosphorylation of the Fas-associated death domain protein.
US11324795B2 Composition comprising Hordeum vulgare extract for preventing or treating short stature
Disclosed is a composition, which comprises Hordeum vulgare extract as an active ingredient and is effective at promoting longitudinal bone growth.
US11324789B2 Method and compositions for treating equine encephalitis
A method of treating equine encephalitis is provided. A composition having at least one cardiac glycoside, such as oleandrin, is used to treat a viral infection causing the encephalitis. The composition can further include at least one triterpene. Alternatively, the composition comprises at least one, at least two, or at least three triterpenes.
US11324786B2 Lactic acid bacteria and use thereof
The present invention relates to the novel lactic acid bacteria Lactobacillus mucosae and Bifidobacterium longum, and specifically, to a composition comprising the novel lactic acid bacteria, the composition enabling the inhibition of the expression of the p16 protein, which is an aging factor, and the inhibition of inflammatory factors, thereby being useful in preventing and treating memory impairment, learning disabilities or mental disorders, and in preventing and treating inflammatory diseases.
US11324785B2 Composition for preventing or treating menopause, containing Lactobacillus intestinalis
The present invention relates to: a novel Lactobacillus intestinalis YT2 strain (deposition number: KCCM11812P); and a composition for preventing, alleviating, or treating menopause, comprising, as an active ingredient, Lactobacillus intestinalis comprising the novel strain. The present inventors have established an animal model for menopause through ovariectomy, confirmed changes of the distribution of intestinal microorganisms by the model, identified and isolated a novel Lactobacillus intestinalis strain among lactic acid bacteria of which the distribution is significantly reduced in the menopausal model, and confirmed effects, by means of the novel strain and previously reported Lactobacillus intestinalis strains, of alleviating menopausal symptoms, such as the inhibition of an increase in body fat, the inhibition of a decrease in bone mineral density, the inhibition of an increase in the pain sensitivity, and the alleviation of depression. Therefore, it is expected that the composition comprising the Lactobacillus intestinalis according to the present invention can be usable for a use of preventing, alleviating, or treating menopause.
US11324784B2 Sleep-promoting composition, and medical composition and food beverage composition using said sleep-promoting composition
Provided is a novel sleep-promoting composition.Provided is a sleep-promoting composition comprising bacteria belonging to Bifidobacterium breve as an active ingredient. The sleep-promoting composition related to the present technology may prolong a sleep time by prolonging non-REM sleep and REM sleep, reducing a spontaneous behavior amount during sleep, or reducing an awakening time during sleep. The sleep-promoting composition related to the present technology may also reduce difficulty in daytime awakening. The sleep-promoting composition related to the present technology may be used for a medical composition or a food and beverage composition.
US11324782B2 Method of preventing obesity using herb ferment
The present invention provides a use of herb ferment for preparing a composition for preventing and/or treating obesity; wherein, the herb is Abelmoschus esculentus. The fermentation process of the present invention can enhance the content of total polysaccharide in the herb ferment, and effectively increase the amylase inhibition rate and the glucosidase inhibition rate of the herb ferment to effectively inhibit the decomposition and absorption of starch and glucoside. The herb ferment of the present invention can also effectively reduce the blood glucose of subjects after meals, and can effectively reduce the body weight, BMI value, waist circumference, visceral fat, average whole body fat percentage, and average body fat percentage, and can be effectively used to regulate blood glucose and blood lipids for weight loss. The herb ferment is prepared by fermenting the herb extract to yeast and lactic acid bacteria.
US11324774B2 Compositions of oral alkaline salts and metabolic acid inducers and uses thereof
Compositions of alkaline salts and metabolic acid inducers and methods of use thereof are provided. The disclosed compositions may be used for stimulating vagal nerve efferent pathways, treating or preventing an inflammatory response or an autoimmune disorder, inhibiting or reducing one or more inflammatory M1 macrophages and/or one or more inflammatory neutrophils in the blood, promoting polarization of macrophages from a pro-inflammatory M1 state to an anti-inflammatory M2 state, and treating or preventing cardiovascular disease or metabolic disorders.
US11324770B2 Delivery of RNA to trigger multiple immune pathways
RNA encoding an immunogen is co-delivered to non-immune cells at the site of delivery and also to immune cells which infiltrate the site of delivery. The responses of these two cell types to the same delivered RNA lead to two different effects, which interact to produce a strong immune response against the immunogen. The non-immune cells translate the RNA and express the immunogen. Infiltrating immune cells respond to the RNA by expressing type I interferons and pro-inflammatory cytokines which produce a local adjuvant effect which acts on the immunogen-expressing non-immune cells to upregulate major histocompatibility complex expression, thereby increasing presentation of the translated protein to T cells. The effects on the immune and non-immune cells can be achieved by a single delivery of a single RNA e.g. by a single injection.
US11324768B2 Applications of triacetyl-3-hydroxyl phenyl adenosine in treating vascular inflammations or improving vascular endothelium functions
There is provided herein a method of treating and/or alleviating vascular inflammation or vascular endothelial function disorders comprising administering 2′,3,′ 5′-triacetyl-N6(3-hydroxyphenyl)adenosine of formula (I): such as in the form of a pharmaceutical composition, to a person suffering from vascular inflammation or vascular endothelial function disorders.
US11324763B2 Malaria transmission prevention agent having rare sugar as effective component thereof and malarial parasite growth regulating agent
Problem: A malaria transmission blocker or a malaria parasite growth inhibitor is provided as a result of finding a druq which inhibits malaria parasite growth in the body of a vector mosquito. Solution: A malaria parasite growth inhibitor or transmission blocker containing a rare sugar such as D-allose or D-psicose as an active ingredient.
US11324760B2 Solid dispersion of dutasteride, method for preparing the solid dispersion, and pharmaceutical composition including the solid dispersion
A solid dispersion of dutasteride for improving the solubility or dissolution rate of poorly soluble dutasteride, a method for preparing the solid dispersion, and a pharmaceutical composition including the solid dispersion are provided. The solid dispersion includes: a coprecipitate including dutasteride and a water-soluble polymeric carrier; and an adsorbent. The dutasteride and the water-soluble polymeric carrier are present in a weight ratio of 1:10-100 in the coprecipitate.
US11324756B2 Dietary supplement
A method of forming a dietary supplement can include steps of creating a composition of matter comprising sakae naa and CDP; and providing the composition of matter in a liquid or solid form. Providing the composition of matter can include filling a container with the composition of matter.
US11324754B2 Dietary supplement
A method of forming a dietary supplement can include steps of creating a composition of matter comprising tianeptine, sakae naa, and optionally, at least one of kava, CDP Choline, and Alpha GPC; and providing the composition of matter in a liquid or solid form. The ingredient of tianeptine can be tianeptine sodium, tianeptine free acid, or both. Providing the composition of matter can include filling a container with the composition of matter.
US11324749B2 Combination therapy for treatment of hematological diseases
The present application relates to treatment of a hematological disease selected from leukemia, lymphoma, and multiple myeloma in a patient in need thereof, comprising administering to the patient: (a) a therapeutically effective amount of a selective JAK1 inhibitor; (b) a therapeutically effective amount of an immunomodulatory agent, and (c) a therapeutically effective amount of a steroid.
US11324748B2 Vasodilators for treatment of heart failure
A method for treating or preventing heart failure involving blockage of small blood vessels is described. The method involves administering to a subject in need thereof a therapeutically effective amount of a vasodilator.
US11324740B2 Use of agonists of type-2 dopaminergic receptors in treatment of conditions caused by elevated vascular endothelial growth factor levels
A method is provided for using of type-2 dopaminergic receptor agonists, for example, cabergoline, in treatment of eye diseases caused by an elevated level of vascular endothelial growth factor (VEGF), particularly in treatment or prevention of diseases of an eye retina resulting from an increase in permeability of blood vessels and their angiogenesis using cabergoline, a dopaminergic D2 receptor agonist.
US11324736B2 Method of Treating Focal Segmental Glomerulosclerosis
A method of treating focal segmental glomerulosclerosis with a compound of Formula I is provided. FSGS may be primary (no known cause) or secondary. The secondary FSGS may be associated with infections or viruses such as HIV, diseases such as sickle cell disease or lupus, toxins or drugs such as anabolic steroids, heroin or pamidronate, nephron loss and hyperfiltration, such as with chronic pyelonephritis and reflux, morbid obesity, or diabetes mellitus.
US11324733B2 Methods for improving memory and cognition and for treating memory and cognitive disorders
This disclosure provides methods for the treatment of disease by administering pharmaceutical compounds. In particular, the disclosure relates to the treatment to improve memory or cognition, or to treat a memory or cognitive disorder, or to treat cognitive symptoms of a disease or condition by administering a T-type calcium channel antagonist.
US11324728B2 Dosing regimens for the treatment of fungal infections
Described herein are dosing regimens for the treatment of fungal infections such as onychomycosis using ravuconazole or a salt, solvate or prodrug thereof.
US11324725B2 Compositions and methods for the inhibition of pruritus
Pharmaceutical compositions comprising a molecular inhibitor of Npr1 are disclosed. Also disclosed are methods of treating, reducing, or preventing acute and/or chronic pruritus in a mammal comprising administering a pharmaceutical composition comprising a molecular inhibitor of Npr1.
US11324723B2 Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence
Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. The methods include treating patients with an antagonist of the serotonin receptor 5-HT3 for such disorders, wherein the patient's serotonin transporter gene SLC6A4 is known to have particular genotypes.
US11324722B2 Compositions and methods for treating ocular disorders
The present disclosure is directed to compositions comprising oxymetazoline and methods of treating various eye disorders related to drooping eyelids, such as ptosis, in a subject comprising administering to the subject compositions comprising oxymetazoline.
US11324720B2 Antiproliferative DNA polymerase inhibitor
Methods for inhibiting cell growth, inhibiting DNA polymerase activity, and inhibiting DNA replication and repair are provided. In a method of inhibiting cell growth, a cell, such as a cancer cell, is contacted with zelpolib or a derivative or pharmaceutically acceptable salt thereof. The cell growth can be inhibited in vivo, and in certain embodiments, the cell growth is inhibited in vitro. In a method for inhibiting DNA polymerase activity, a DNA polymerase is contacted with zelpolib or a derivative or pharmaceutically acceptable salt thereof. In certain embodiments, the DNA polymerase is Pol δ. In a method for inhibiting DNA replication and repair, a cell, such as a cancer cell, is contacted with zelpolib or a derivative or pharmaceutically acceptable salt thereof. The DNA replication and repair can be inhibited in vivo, and in certain embodiments, the DNA replication and repair is inhibited in vitro.
US11324716B2 Derivatives of korormicin useful as antibiotics
Described herein is a process for antibiotic development comprising: (a) generating a compound of formula (III): or a salt or stereoisomer or prodrug thereof; wherein R1-R3 and R5-R10 are independently selected from H, alkyl group, substituted alkyl group, halogen, OH, NH2, or SH; R4 is H, alkyl group or substituted alkyl group; X1-X2 are independently selected from ═O, ═S, ═NH, H, alkyl, halogen, OH, SH, or NH2; W is a saturated acyclic hydrocarbon chain of 1 to 15 carbon atoms; and Z is a neutral or positively charged organic group comprising a nitrogen or phosphorus atom; and; and (b) determining efficacy of the compound to inhibit growth of a bacteria. Systems of drug development of these antibiotic compounds are also described.
US11324713B2 Organoarsenic compounds and methods for the treatment of cancer
A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R1 and R2 are independently C1-30alkyl (R3, R3′, R4, R5, W and “n” are as defined in claim 1) in particular where the compound is S-dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S-dipropylarsino-1-thioglycerol.
US11324711B2 Composition and uses for influencing hair growth
The invention describes a combination of at least one aromatase inhibitor selected from the group of chemical-synthetic aromatase inhibitors and aromatase inhibition exhibiting extracts of soya beans and rapeseed, respectively, and at least one plant extract that contains one or more active ingredient substance(s) extracted from the plant, which is(are) selected from the group of 5α reductase type I and/or type II inhibitors and androgen receptor blockers, said combination being contained for example in a composition and having special properties for influencing hair growth. Uses of this combination are also described.
US11324710B2 Topical pharmaceutical compositions for treating skin conditions
Topical pharmaceutical compositions for treating a skin condition or disorder are provided. The topical pharmaceutical compositions can be formulated as lotions containing a therapeutically effective amount of an active agent, such as tretinoin, a viscosity increasing agent, and advantageously small amounts of both a polymeric emulsifier and an oil component. The topical compositions of the present invention are tolerated exceptionally well by subjects to whom the compositions are administered.
US11324709B2 Fatty acid amides and uses thereof in the treatment of addiction disorder and addiction related conditions
The present invention is directed to a fatty acid amide of an amino acid, including a stereoisomer and a salt thereof for use in the treatment of a patient suffering from any type of addiction disorder, substance abuse disorder, including any condition and symptom associated therewith and including withdrawal syndrome and relapse addiction during and after a rehabilitation treatment of said patient.
US11324708B1 Niclosamide formulations for treating disease
The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.
US11324706B2 Composition for inhibiting growth of breast cancer stem cells containing phenylacetaldehyde
Disclosed are a composition and a perfume composition for inhibiting growth of breast cancer stem cells containing phenylacetaldehyde or a pharmaceutically acceptable salt thereof as an active (effective) ingredient, and a pharmaceutical composition, a food composition or the like for inhibiting metastasis of breast cancer, or treating or preventing breast cancer, including the composition. The phenylacetaldehyde inhibits growth of breast cancer cells and formation of breast cancer stem cells. In addition, the phenylacetaldehyde inhibits expression of self-renewal genes such as Nanog, Sox2, Oct4, and CD44 known to be specifically expressed in breast cancer stem cells, inhibits production of IL-6 known to be involved in formation of mammospheres of breast cancer stem cells, and inhibits STATS signaling pathways. Accordingly, the compound inhibits growth of breast cancer stem cells and is useful for the treatment of breast cancer.
US11324705B2 Transdermal drug delivery system
Provided herein is a water- and sweat-resistant transdermal drug delivery system for application to the skin of a mammal that comprises a patch having a diameter between 1 and 8 cm in length and a surface area between 4 and 8 cm2. Also provided are methods of producing the transdermal drug delivery system and methods of treatment comprising the use of the transdermal drug delivery system.
US11324702B2 Soft gel compositions and capsules made from the same
The present disclosure generally relates to film-forming compositions and capsules formed from such compositions, including processes for using such compositions to make capsules. In some embodiments, the film-forming compositions are free of animal products and carrageenan.
US11324701B2 Method for freeze-drying cells in a hydrogel comprising nanofibrillar cellulose and freeze-dried cells in an aerogel comprising nanofibrillar cellulose
The present disclosure provides a method for freeze-drying cells in a hydrogel comprising nanofibrillar cellulose, the method comprising providing a hydrogel comprising nanofibrillar cellulose, providing cells, combining the cells and the hydrogel comprising nanofibrillar cellulose to form a cell system, and freeze drying the cell system to obtain dried cells in a hydrogel comprising nanofibrillar cellulose. The present disclosure also provides a freeze-dried hydrogel comprising nanofibrillar cellulose and cells.
US11324700B2 Method of production of inhalable composite particles using a three-fluid nozzle
A method of preparing a pharmaceutical formulation which is suitable for inhalation, the method comprising: providing a solution comprising a first solvent or mixture of solvents and a poorly water soluble active agent; providing a second solution comprising a second solvent or mixture of solvents and an excipient. The first and second solvents or mixture of solvents are removed by simultaneously drying both solutions in a spray dryer equipped with a three-fluid nozzle to produce particles comprising an active agent and an excipient.
US11324696B2 Suspensions and diluents for metronidazole and baclofen
Suspensions of metronidazole or baclofen and/or salts or ester derivative thereof, such as metronidazole benzoate, are disclosed. The suspension my include metronidazole or baclofen, and/or a salt or ester derivative thereof a hydrocolloid stabilizer, simethicone emulsion, a buffer, such as sodium citrate, (dihydrate), a preservative, a thickening agent, a sweetener, and water.
US11324695B2 Transdermal solvent system and methods of use
Described herein are transdermal solvent systems comprising at least one active agent in solution in a base solution, the base solution comprising at least one fatty acid ester compound, at least one monoterpene compound and a co-solvent in the form of DMSO or DMI and at least one plant oil. The base solution was found to be highly versatile and provide superior or at least comparable skin penetration efficacy and active agent compatibility. Methods of treatment, uses of the solvent system and methods of manufacture are also described.
US11324690B2 Composition for restorative vaginal lubrication and a method of use thereof
A composition for restorative vaginal lubrication and a method of use thereof facilitates enhances the overall vaginal health. The composition includes a quantity of water, a quantity of glycerin, a quantity of cetearyl alcohol, a quantity of glyceryl stearate, a quantity of avocado oil, a quantity of squalene oil, a quantity of lecithin, a quantity of benzoin oil, a quantity of xanthan gum, a quantity of citric acid, a quantity of potassium sorbate, a quantity of Dehydroepiandrosterone (DHEA), a quantity of elderberry extract, a quantity of damiana extract, a quantity of progesterone, a quantity of pomegranate oil, and a quantity of sodium benzoate. The composition is homogeneously mixed into a vaginal salve that may be both externally and internally applied with the vaginal area in order to moisturize the vaginal area and enhance sexual pleasure during sexual activity. The vaginal salve also promotes blood circulation for the vaginal area.
US11324686B2 Occlusive formulations
The invention provides a topical o/w emulsion which moisturizes, and protects, repairs or restores the skin lipid barrier of a mammal. The topical o/w emulsion composition comprises: (a) a discontinuous oil phase; (b) a continuous aqueous phase comprising water; (c) a thickening agent; (d) at least one lamellar membrane structure comprising (i) a phospholipid, (ii) a fatty alcohol, and (iii) a fatty acid; and wherein in use the composition has a water vapor transmission rate of less than about 70 g.m−2.hr−1 measured in vitro using the modWVTR test methodology.
US11324684B1 Thermal control of hair color-altering compositions
The disclosure relates to thermal control of compositions for altering the color of hair, in particular to hair bleaching compositions comprising thermal control agents, hair color-altering compositions comprising the hair bleaching compositions and/or thermal control agents, methods for preparing and using the hair color-altering compositions, and kits comprising the hair bleaching compositions and/or thermal control agents.
US11324678B2 Core shell silica particles and uses thereof as an anti-bacterial agent
This invention provides core shell silica particles, wherein each core shell silica particle comprises a silica core, and a surface of the silica core etched with group I metal silicate. These core shell silica particles have high surface charge density and anti-bacterial activity. Also provided are compositions comprising core shell silica particles, process of making the core shell silica particles and methods of reducing or inhibiting bacterial activity by administering the core shell silica particles or compositions thereof.
US11324672B2 Method for preparing hyaluronic acid dermal fillers, dermal fillers obtained thereby and their use
The present invention generally relates to the field of hyaluronic acid (HA) dermal fillers, and more specifically to methods for preparing crosslinked HA-based compositions in the form of a gel comprising high-temperature dialysis and/or crosslinking in the presence of phosphate and an alkaline metal halide salt. The present invention further relates to crosslinked HA-based gel compositions prepared by said methods and their use as dermal fillers in aesthetic applications such as wrinkle treatments.
US11324670B2 Cocoa butter powdered moisturizer
The present invention is a cocoa butter powdered moisturizer with the addition of cocoa powder serving as a stabilizing agent. The cocoa butter is grated and/or shredded into a fine granulated form and is supplemented with the stabilizing cocoa powder such that the resulting moisturizer attains a consistent, usable form. The resulting moisturizer is stable at room temperature and provides an SPF-15 level of sun protection for the skin.
US11324668B2 Pacifier to train proper tongue position
A pacifier for an individual, the pacifier including a shield, a handle extending from a first side of the shield, and a nipple extending from a second side of the shield. The handle defines a longitudinal axis and the nipple is inclined downwardly with respect to the longitudinal axis. A shelf connects the nipple to the shield. In different configurations the shelf includes varying widths and in other configurations the shelf width is different than a width of the nipple. A core extends from the handle, through the shield and into the nipple.
US11324667B2 Silicone tube coupled baby feeding bottle
The present invention relates to a baby feeding bottle. The baby feeding bottle employs a simple structure in which an assembly portion having a ring-shaped assembly groove is formed on the outside of the top of a feeding bottle body, a horizontal stop protrusion portion and a vertical coupling protrusion portion are formed on the outside of the bottom of the feeding bottle body, a silicone tube is fined into the outside of the feeding bottle body, a ring coupling portion at the upper end of the silicone tube assembly groove is coupled to the assembly portion in a sealed manner by being inserted to the assembly portion, and a horizontally bent portion at the lower end of the silicone tube is coupled to the stop protrusion portion in a sealed manner by locating the horizontally bent portion and then pressing the horizontally bent portion with the sealing cap.
US11324665B2 Medication intelligent device
A medical intelligent device is for use with a medical jar. The medical jar defines an accommodating space for containing at least one medicine. The medication intelligent device includes a cover and an auxiliary medicine deliver. The cover is detachably mounted on the medical jar. The auxiliary medicine deliver is disposed on the cover and includes a main control chip and a medicine delivery gate electrically connected to the main control chip. The main control chip is used to move the gate between a closed position and an opened position relative to the cover. In the closed position, the medicine delivery gate closes the accommodating space. In the opened position, the medicine delivery gate opens the accommodating space.
US11324663B2 Method and apparatus for transferring a liquid drug to a collapsible reservoir
The invention concerns a method and an apparatus for transferring an amount of a liquid drug (11) from a supply container (1) having stored the liquid drug (11) to a collapsible reservoir (2), the method including and the apparatus enabling the steps of: a) providing a fluid connection (3) between the supply container (1) and the collapsible reservoir (2); b) subjecting the liquid drug (11) stored in the supply container (1) to an environmental pressure; c) subjecting the collapsible reservoir (2) to a positive pressure relative to the environmental pressure, thereby collapsing the collapsible reservoir (2) and transferring gas comprised in the collapsible reservoir (2) from the collapsible reservoir (2) to the supply container (1); d) subjecting the collapsible reservoir (2) to a negative pressure relative to the environmental pressure, thereby expanding the collapsible reservoir (2) and transferring the amount of the liquid drug (11) from the supply container (1) to the collapsible reservoir (2).
US11324662B2 RFID tag and blood container/system with integrated RFID tag
The present disclosure relates to arrangements for attaching an RFID tag to a liquid container, and particularly to a blood components container. The RFID tag may be inserted in an enclosure, such as peel tab, or in a sealed cup attached to a container port. The tag could alternately be embedded in a molded plug or component attached to a port. The RFID antenna could be painted or stamped on the surface of the container. Or the tag could be inserted into the container to float freely in the liquid components. The RFID source may be secured around the neck of a rigid or semi-rigid container, attached with a tether or attached to a connector assembled in association with a blood component or other fluid flow path.
US11324661B2 Medical container with NFC antenna
A pharmaceutical container includes a cylindrical hollow container body defining a hollow chamber to receive a pharmaceutical liquid, the container body including a portion on a sidewall) of the container body, wherein the portion has a longitudinal extension along the longitudinal axis of the container body and a circumferential extension along the circumference of the container body, thereby forming a window through the sidewall of the container body into the hollow chamber. In embodiments of the invention, the window comprises two long edges and two short edges, and a Near Field Communication (NFC) antenna. In embodiments of the invention, the antenna comprises one or a plurality of nested antenna windings.
US11324659B1 Bathing installation fitting and grommet assembly
A fitting assembly for installation in an opening in a tub shell wall of a bathing installation tub. A resilient grommet is sized to be inserted into the opening and has an interior peripheral recess defined in a wall portion, having a recess cross-sectional configuration. A fitting body has a protruding external rib having a rib cross-sectional configuration complimentary to the recess cross-sectional configuration, the rib positioned on the fitting body so that when the fitting body is inserted into the grommet, the rib is received into the recess on the grommet. The grommet and fitting are configured such that the recess and the rib are positioned behind the back surface of the shell wall when installed in the opening, and the grommet is compressed by the edge of the shell opening and pushed outwardly by the rib to lock the fitting into the shell opening.
US11324658B2 Device for controlling the enrichment of nitric oxide levels and a control method
A device is provided for controlling the nitric oxide levels within the lungs of a subject. The device comprises a detector for detecting the respiration cycle of the subject and a stimulator for applying an acoustic or vibratory stimulus to the subject. The stimulator is controlled in dependence on the detected respiration cycle. In particular, acoustic stimulation may be provided at the onset of inspiration. In this way, the nitric oxide flow can be controlled in a way to ensure that the paranasal nitric oxide is nearly fully inspired. This provides a higher nitric oxide concentration in the lung/alveoli.
US11324649B2 Mobility scooter with easy access
The invention relates to a mobility scooter for individual mobility of a person, comprising a chassis, two front wheels aside the chassis and at least one rear wheel, a seat with a seat base and armrests for the person, a footrest on the chassis that extends between the seat and the front wheels, and an electronic controller assembly, wherein the mobility scooter has a driving mode and a boarding mode, wherein in the driving mode the seat base and the armrests are in the driving position, and wherein in the boarding mode the seat base or at least one of the armrests is in the boarding position, wherein the electronic controller is configured to steer the front wheels in the boarding mode into the sideward steering direction that is opposite to the side to which the seat base or the armrest is swung in the boarding position.
US11324647B2 Patient transport apparatus with adjustable handles
A patient transport apparatus includes a support structure. The support structure includes a base, a frame, and a patient support surface to support a patient. One or more handle assemblies are coupled to the frame to maneuver the patient transport apparatus. The handle assemblies include one or more handles to be manipulated by a user. The handles are capable of being adjusted to facilitate maneuvering of the patient transport apparatus, such as pushing/pulling the patient transport apparatus along a floor surface, lifting the patient transport apparatus over obstacles, loading the patient transport apparatus into an emergency vehicle, and/or unloading the patient transport apparatus from the emergency vehicle.
US11324645B2 Garment-facing laminates and methods for making the same
An absorbent article including a liquid permeable topsheet on a wearer-facing side of the absorbent article and a garment-facing laminate on a garment-facing side of the absorbent article is disclosed. The garment-facing laminate includes a backsheet film and a nonwoven layer joined to the backsheet film. The nonwoven layer defines a plurality of apertures. At least 3 of the plurality of apertures in a repeat unit have a different Effective Aperture Area, according to the Aperture Test herein, a different shape, and a different Absolute Feret Angle, according to the Aperture Test herein. The absorbent article includes an absorbent core disposed at least partially intermediate the liquid permeable topsheet and the garment-facing laminate.
US11324640B2 Compression sleeve
Compression sleeve (1) for application circumferentially around a human limb (10) to exert therapeutic pressure on the limb. The compression sleeve has a fabric (80), which comprises viscoelastic strands (90) for providing the fabric with viscoelastic properties.
US11324638B2 Bandage which enables examining or treating a wound without removing the adhesive
The base of this bandaging system is attached to the skin around a wound by adhesive and supports the edges of the lid, which covers the wound and can easily be removed and replaced or re-used many times to facilitate examining or treating the wound while the base remains in place. The bandaging system has multiple embodiments to accommodate various situations. An embodiment with generally planar components is very simple but may cause vertical pressure on the skin near the wound when the lid is removed or attached. Such pressure is avoided by alternative embodiments in which the components have non-planar parts. Some embodiments have a hinge on an edge of the lid which allows the wound to be uncovered without detaching the lid. The components which latch lids to bases contribute to making the systems easy, quick, convenient, and comfortable to use.
US11324634B2 Plug with isthmus anchor for treating patulous Eustachian tube
A plug is configured to maintain position within a Eustachian tube of a patient. The plug includes a proximal portion and a distal portion. The proximal portion includes a first body dimensioned bear radially outwardly against the Eustachian tube of the patient. The distal portion includes an anchoring assembly that is configured to lock the plug in the Eustachian tube of the patient. The plug may be formed of a bioabsorbable material.
US11324626B2 Device and method for opening an airway
A device and a method for creating and/or maintaining an obstruction free upper respiratory passages. The device is configured to fit under the chin of a subject adjacent to the subject's neck at an external location corresponding approximately with the subject's soft tissue associated with the neck's anterior triangle. The device is capable of exerting negative pressure on the surface of a subject's neck, displacing the soft tissue forward and enlarging the airway.
US11324625B1 Internal nasal splint
The internal nasal splint is used in pairs, one on each side of the septum, to support the septum, maintain patent airways on each side of the septum, and reduce or mitigate the incidence of hematomas and post-surgical adhesions following such nasal surgeries as septoplasty, removal of nasal polyps, correction of nasal fractures, etc. The two splints are symmetrical, and each includes an arcuate septal support splint portion defining a delivery lumen or tube having a plurality of medially spaced delivery ports or orifices, and a lateral flared splint portion defining an airway passage extending between the opening of the nostril and the internal nasal valve, the two splint portions being joined by an isthmus or bridge. A suture access pad is provided on each internal nasal splint to facilitate suturing the splints to the septum when placing the splints in the corresponding naris or nostril during the surgery.
US11324624B2 Traction splints and methods of using traction splints
Portable traction splints for applying traction to an injured patient's limb may be extendable from a collapsed configuration adapted for transportation and storage towards an extended configuration adapted for applying traction to the injured patient, using telescoping members. One or more straps may be provided for securing the traction splint to the patient. One or more of such straps may include a tourniquet portion and/or may be configured to be oriented in different directions relative to the telescoping members. The disclosed traction splints may include a traction mechanism including a traction cord to apply traction to the patient's limb. The traction cord may be secured and maintained at a desired tension via a catch and a cleat in the inner member. Additionally or alternatively, a longitudinal cord groove and an inner hollow of the inner member may define a cord path for the traction cord.
US11324623B2 Body trunk supporter and wear provided with same
A body trunk supporter provided with: a belt-like lower band section that is adapted to be wrapped around and positioned at the pelvis of a user; an X-shaped stretchable middle band section that has a pair of lower end parts joined to the lower band section and that presses areas of the lumbar region of the user; and a pair of upper band sections that are jointed to a pair of upper end parts of the middle band section and that are adapted to be wrapped around and positioned at the chest of the user, wherein the pair of lower end parts of the middle band section are configured to be joined to areas ranging from positions that are immediately lateral to the pelvis of the user to adjacent anterior positions thereof in the lower band section; and the pair of upper band sections are configured to be separated from each other and to extend in bilaterally opposite directions in an unfolded state, and are configured to be wrapped around and positioned near fifth to tenth ribs of the chest of the user.
US11324620B2 Systems and methods for measuring volume of potential sleeve in a sleeve gastrectomy
One or more medical devices may be provided that may be used, for example, in bariatric surgery including a vertical sleeve gastrectomy. Occlusion devices can be integrated with a catheter or tube to occlude one or more proximal or distal landmarks of a stomach and a stapling guide may be used to occlude a lateral boundary of the stomach to define a cavity. A volume of the potential resultant sleeve may be determined by inserting fluid or gas into the catheter or tube, measuring pressure, and calculating the volume of the cavity.
US11324619B1 Acute and chronic devices for modifying flow in body lumens and methods of use thereof
The acute and chronic devices and methods described herein include a body lumen fluid flow modulator including an upstream flow accelerator and a downstream flow decelerator. The fluid flow modulator preferably includes one or more openings that define a gap/entrainment region that provides a pathway through which additional fluid from a branch lumen(s) is entrained into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator. Delivery devices including a sheath and inner assembly also are provided for delivering the flow modulator to the body lumen. The delivery device may maintain the flow modulator in its collapsed, delivery state upon retraction of the sheath for ease of readjustment within the body lumen prior to full deployment of the flow modulator within the body lumen.
US11324616B2 System for deploying a capacitive shape memory catheterization device and methods for use therewith
A system for deploying a shape memory catheterization device within a patient, includes a catheter for endovascular insertion of the shape memory catheterization device. A heat source heats the shape memory catheterization device above the transition temperature. A transformation data generator includes a circuit driver for driving a circuit that includes at least one capacitive element of the shape memory catheterization device and a detection circuit for generating transformation data based on a capacitance of the at least one capacitive element, wherein the transformation data indicates a shape transformation of the shape memory catheterization device from a catheterization shape to a transformed shape.
US11324614B2 Balloon expanded polymer stent
A medical device includes a polymer stent (or scaffold) crimped to a catheter balloon. The stent, after being expanded from a crimped state by the balloon, provides a crush recovery of about 90% of its expanded diameter after being pinched or crushed by an amount equal to about 50% of the expanded diameter. The stent has a pattern including a W-shaped or W-V shaped closed cell and links connecting the closed cells.
US11324612B2 Breathable residual-limb socket system
A liner defines a pouch, an opening, a cup, and a first ring positioned on the pouch distal to the opening. The pouch is air-permeable and defines an internal volume for receiving a residual limb. The opening defined by the pouch provides access to the internal volume. The cup is air-impermeable and is positioned on the pouch distal to the opening. The liner is combined with an adapter for connecting a residual limb to a prosthetic limb. The adapter has a socket for receiving the cup, at least one hole positioned within the socket for drainage therefrom and sleeve extending from the socket and surrounding a central space. The adapter also has at least one vent positioned in the sleeve and overlies the air permeable material.
US11324607B2 Surgical method and instrumentation assembly for positioning an ankle prosthesis
This surgical ankle repair method comprises the steps of providing an instrumentation assembly for positioning an ankle prosthesis, the instrumentation assembly including a talar alignment instrument and a cutting block, the talar alignment instrument comprising a front portion and two fins extending from the ends of the front portion, said fins being adapted to be positioned in gutters extending below a tibia of a patient and around a trochlea of a talus of the patient, each fin including a reference marker, the cutting block comprising a tibial alignment structure and a recess which engages a protrusion provided on the talar alignment instrument, positioning the talar alignment instrument such that the fins are disposed in the gutters extending below the tibia and around the trochlea of the talus; aligning the talar alignment instrument so that the fins are parallel to the rotational plane of the talus, perpendicular to the rotational axis of the talus, and so that the reference markers are aligned with a longitudinal axis of the tibia; confirming alignment of the reference markers via imaging technology; mechanically attaching the talar alignment instrument to the talus; fastening the cutting block to the talar alignment instrument such that the recess engages the protrusion locked in a parallel orientation to the rotational plane of the talus; rotating the talus such that the tibial alignment structure is in a parallel alignment to the longitudinal axis of the tibia, thereby correcting any varus or valgus deformity of the talus; attaching the tibial alignment structure to the tibia; and performing a first resection of the talus and at least one resection of the tibia using the cutting block.
US11324602B2 Bionic artificial interphalangeal joint
The present invention discloses a bionic artificial interphalangeal joint. The bionic artificial interphalangeal joint includes three sets of proximal prostheses and distal prostheses matched with the proximal prostheses and respectively corresponding to the three joints from the metacarpal bone to the distal phalanx. According to the specific position of the joint to be replaced, the corresponding artificial interphalangeal joint can be selected for replacement. Among them, the bionic artificial interphalangeal joint that can be installed between the metacarpal bone and the proximal phalanx has multiple degrees of freedom, which allows the proximal phalanx to bent in any direction like a real finger, and the bending angle of the proximal phalanx can be up to about 90 degrees when the proximal phalanx is bent toward the inner side of the finger.
US11324601B2 Talus implant
At least one embodiment comprises a talus implant comprising: a body section; a neck section; a crown, wherein the crown is positioned at a top portion of the body section; at least one wing coupled to the body section, wherein the wing extends out from the body section. At least one embodiment further comprises at least one screw hole positioned in at least one of the neck section and the body section. In at least one embodiment the outer surface of the implant is polished. In at least one embodiment a portion of the outer surface is polished while a portion of the outer surface is roughened.
US11324596B2 Inflatable penile prosthesis with reinforced cylinder
According to an aspect, an implant includes an inflatable member and a pump assembly configured to facilitate a transfer of a fluid from the reservoir to the inflatable member. The inflatable member defining a lumen and including a structural member. The inflatable member includes a coating.
US11324594B2 Prosthetic heart valve
This disclosure relates generally to prosthetic valves and methods and systems for deploying, positioning, and recapturing the same. A prosthetic valve includes one or more support structures. At least one of the one or more support structures defines an elongate central passageway of the prosthetic valve. The prosthetic valve can also include a plurality of leaflet elements attached to at least one of the one or more support structures and disposed within the elongate central passageway for control of fluid flow through the elongate central passageway. At least one of the one or more support structures is configured to biodynamically fix the prosthetic valve within a native valve such as, for example, a native tricuspid valve of a heart.
US11324592B2 Naturally designed mitral prosthesis
A mitral valve prosthesis to be implanted in a heart, comprises an asymmetrical ring, the asymmetrical ring is dimensioned to mimic a native mitral annulus of a patient; an anterior flexible leaflet and a posterior flexible leaflet, said leaflets suspended from the asymmetrical ring and configured to substantially coapt with each other; and at least four sets of cords, each set of cords attached to the anterior or posterior leaflet on a first end and attached into a cap on a second end, the cap is configured to be attached onto papillary muscles of the heart on another end of the cap.
US11324585B2 Method for producing shell and foam filler for a breast implant
A method for manufacturing a breast implant includes producing a silicone shell of the breast implant by rotating a mold containing a silicone material to evenly spread the silicone material over an inner surface of the mold. Subsequently, an elastic filler material including silicone foam is formed in the shell by (i) injecting into the mold a mixture comprising silicone gel and gas bubbles and (ii) rotating the mold to homogenize the mixture.
US11324582B2 Docking graft for placement of parallel distally extending grafts assembly and method
The techniques of this disclosure generally relate to an assembly including a docking graft. The docking graft includes a main graft defining a main lumen, a first internal lumen within the main lumen, a second internal lumen within the main lumen, and a main docking lumen within the main lumen. The first and second internal lumens are configured to receive first and second bridging stent graft therein. The main docking lumen is configured to receive a tube graft therein. The first internal lumen, the second internal lumen, and the main docking lumen being parallel to one another and extending an entire length of the docking graft when the docking graft is in a relaxed configuration. The docking graft forms the foundation, or anchor device, for attachment of the first bridging stent graft, the second bridging stent graft, and the tube graft within the aorta.
US11324580B2 Sterile packaging container
The present disclosure in one aspect provides a sterile packaging container comprising a container body with a cross-sectional shape that is constant along the majority of the longitudinal axis, a cover and a closure assembly that inhibits the passage of microbial contaminants. The container is configured such that the interior of the container can be sterilized. The sterile packaging container described herein allows one to manufacture a sterile packaging tube exercising the smallest possible volume.
US11324579B2 Gender-specific mesh implant with barrier for inguinal hernia repair
Disclosed herein are gender-specific implantable mesh for inguinal hernia repair in a patient, comprising: a fabric layer comprising a side defining a surface area wherein the fabric layer is configured to enable tissue adhesion to said mesh; an anti-adhesive barrier comprising a shape configured to prevent direct contact between the fabric layer and both a spermatic cord and a genital nerve upon implantation, wherein the shape covers a part of the surface area on the side of the fabric layer, the part being less than 25%, and wherein the shape is oblique to a horizontally-oriented centerline and a vertically-oriented centerline; and a keyhole configured to fit the genital nerve and the spermatic cord of the patient therethrough without constriction, wherein the keyhole is oblique and inferior to a horizontally-oriented centerline and medial to a vertically-oriented centerline.
US11324578B2 Draining biological patch
The present invention relates to an innovative biological prostheses, equipped with a drainage system, designed for all surgical applications where there is any risk of hematomas or seromas, which not only allows to minimize adverse events arising from its application, but allows also to improve the effectiveness of the functional reconstruction. The prosthesis of the present invention is a surgical prosthesis made of animal derived collagen having a peripheral outline and a drainage portion comprising a plurality of drainage holes which are located in one or more independent groups each of which has a regular body-centered polygon layout.
US11324577B2 Dental tool holder
An apparatus and method for a dental tool holder for use with a cassette assembly for cleaning and preparing dental tools for use. The dental tool holder includes a body with a set of openings. A set of slits extend through the exterior of the body to the openings for the insertion of tools. Opposite of the openings, a valley can be formed in the body at each slit. Additionally, slots can be provided between each set of one slit and one opening.
US11324576B2 Suction device
The invention relates to a suction device for intraoral use, comprising a suction line and a tongue protection, said suction line being bent substantially U-shaped, which are configured by a molded part, in particular integrally with one another. The suction tube comprises a connection which points mesially for a suction hose. In the course of the suction tube the connection is adjoined by an upper U-leg, a mesial U-central portion and a lower U-leg, said legs extending distally from the U-central portion. The lower U-leg comprises suction openings and is surrounded by a suction sponge which covers the suction openings. The suction tube terminates at the distal end of the lower U-leg in an end suction opening which is covered by the suction sponge.
US11324575B2 Pump body of oral irrigator
A pump body of an oral irrigator includes a mount, a motor disposed at a rear end away from the mount, a pinion disposed on a shaft of the motor, an annular gear disposed on a shaft member to mesh with the pinion, a cam disposed in the annular gear and adjacent to one side, a linkage secured to the cam, front and rear plungers disposed on a front end of the linkage, and a cylindrical tube disposed on the plungers in the mount. The rotation of the cam only allows the linkage to repetitively move in a back-and-forth linear motion. Wear between the plungers and the cylindrical tube is decreased to a minimum and leakage is prevented.
US11324574B2 Three-dimensional printed bone supported sinus guide for edentulous maxillary arch
An accurate and precise surgical guide for dental procedures, especially a procedure involving a subject with few or no teeth as well as methods for making and use of such guides.
US11324567B2 Expandable tissue cavity marker devices, systems and deployment methods
Embodiments relate to expandable tissue cavity markers and corresponding systems and deployment methods. In one embodiment, an expandable tissue cavity marker comprises a pouch and at least one radiopaque marker element. The pouch can transition between a compressed state, in which a profile or dimension of the tissue cavity marker is reduced such that the tissue cavity marker can be deployed through a minimally invasive surgical procedure incision, and an expanded state, in which a profile or dimension of the tissue cavity marker is increased such that the tissue cavity marker fills or defines a volume of a tissue cavity. In one embodiment, the pouch can be transformed between the compressed state and the expanded state by delivery of a fill material into the pouch. The pouch can comprise one or more functional materials in embodiments, including materials that provide an anti-infection, hemostasis, anti-migration, medicinal, or other function to the tissue cavity marker.
US11324562B2 Latex glove inflation assembly
A latex glove inflation assembly includes a housing that is fluidly coupled to a vacuum source for purging the housing of air. The housing has a pair of glove apertures extending into an interior of the housing. A plurality of engagements is each distributed around a respective one of the glove apertures. Each of the engagements engages a wrist opening on a respective pair of latex gloves when the engagements are turned on. The latex gloves are inflated when the housing is purged of air thereby facilitating a user to insert their hands into the gloves. Each of the engagements releases the latex gloves when the engagements are turned off. A release is coupled to the housing and the release facilitates air to fill the housing when the release is turned on thereby facilitating each of the latex gloves to deflate around the user's hands.
US11324559B2 Robotic-assisted navigation and control for airway management procedures, assemblies and systems
Airway management methods, devices, assemblies and systems. Methods, devices, assemblies and systems may include robotic movement and control of an intubation tube introducer or guide, and may include utilizing image data from one or more image sensors. The methods, devices, assemblies and systems may optionally be used in endotracheal intubation procedures.
US11324558B2 Electromagnetic distortion detection and compensation
Systems and methods for electromagnetic (EM) distortion detection and compensation are disclosed. In one aspect, the system includes an instrument, the system configured to: determine a reference position of the distal end of the instrument at a first time based on EM location data, determine that the distal end of the instrument at a second time is static, and determine that the EM location data at the second time is indicative of a position of the distal end of the instrument having changed from the reference position by greater than a threshold distance. The system is further configured to: determine a current offset based on the distance between the position at the second time and the reference position at the first time, and determine a compensated position of the distal end of the instrument based on the EM location data and the current offset.
US11324556B2 Combining catheter visualization from different coordinate frames
In one embodiment, a medical probe tracking system includes a first probe, a magnetic field generator to generate a magnetic field, and processing circuitry to measure first electrical currents between body surface electrodes and first probe electrodes, receive magnetic position signals from a magnetic field sensor of a second probe, compute first position coordinates of the first probe in a first coordinate frame responsively to distribution of the first electrical currents, render an initial 3D representation of the first probe in the first coordinate frame and then compute a current-position map with respect to a second coordinate frame defined by the magnetic field generator, find a transformation between the first and second coordinate frames, apply the transformation to the first position coordinates yielding second position coordinates, and render a modified 3D representation of the first probe according to the second position coordinates in the second coordinate frame.
US11324555B2 Instrument port including optical bulb secured to port body
An instrument port includes a port body, a bulb disposed at the distal end of the port body, a base body disposed at the proximal end of the port body, a hollow cylindrical body mechanically coupled to the base body, and a plurality of connecting rods disposed parallel to the port body. Each connecting rod includes a distal rod portion that is mechanically coupled to a respective distal-facing exterior surface of a bulb flange and a proximal rod portion that is mechanically coupled to a respective proximal-facing surface of the base body. A spring applies a spring force against the port body to press the port body into the bulb to mechanically secure the bulb to the base body.
US11324553B2 Side fire optical fiber for high power applications
A side fire optical fiber tip is provided for use in high power laser applications having outputs of greater than or equal to 50 Watts. A predetermined length of an output tip on the distal end of the optical fiber is formed with an optical fiber core and cladding layer of preselected thickness wherein the cladding to core diameter ratio is at least as great as 1.2. A side fire surface is formed on the distal end of the core/clad output end. Over this optical fiber output end, a pure silica capillary tube is fused to the predetermined length of exposed cladding where the outermost cladding is also pure silica to reduce thermal mismatch during the fusion process. By having the refractive index at the fusing interface matched, and bubbles or gaps eliminated or prevented, it is possible to substantially eliminate Fresnel reflection losses at this interface.
US11324551B2 Microwave ablation catheter, handle, and system
A handle for longitudinal movement of a first tubular member over a second tubular member includes a handle body, a nose cone, a locking mechanism, and a retraction control. The nose cone has a sleeve and an outer wall that define a control channel therebetween. The nose cone is moveable over the handle body between extended and retracted positions. The locking mechanism has locked and unlocked positions for selectively fixing the nose cone in the extended and retracted positions. A finger of the retraction control is positioned within the control channel of the nose cone. The retraction control has first and second positions relative to the nose cone for transitioning the locking mechanism between the locked and unlocked position and for moving the nose cone between the extended and retracted positions.
US11324546B2 Tissue extraction devices and methods
Tissue may be cut and extracted from an interior location in a patient's body using a probe or tool which both effects cutting and causes vaporization of a liquid or other fluid to propel the cut tissue through an extraction lumen of the cutting device. The cutting may be achieved using an electrosurgical electrode assembly, including a first electrode on a cutting member and a second electrode within a cutting probe or tool. Thus, over a first cutting portion, radio frequency current may help cut the tissue and over a second or over transition region, the RF current may initiate vaporization of the fluid or other liquid to propel the tissue from the cutting device.
US11324542B2 RF generator for an electrosurgical instrument
A device is provided for generating RF power for an electrosurgical instrument, wherein the circuit provides the electrosurgical current according to a specified set of predefined parameters. The invention further includes at least one read and write RFID that reads information from a RFID tag. The circuit changes the parameters based on the information.
US11324541B2 Thermal incision apparatus, system and method
Thermal cutting surgical instruments incorporate a blade incorporating a first substrate of high thermal conductivity material in the heated portion of the blade and a support and, the first substrate of high thermal conductivity material joined to a second substrate of low thermal conductivity material in the support region of the blade; an electrically insulative dielectric layer disposed on the first surface of the first substrate and on the first surface of second substrate; an electrically resistive heating element disposed on the electrically insulative dielectric; electrically conductive power leads and electrically conductive sense leads disposed on the electrically insulative dielectric layer and that are in electrical communication with the electrically resistive heating element; and an electrically insulative dielectric overcoat layer disposed on the electrically resistive heating element and on the distal portion of the electrically conductive power leads and electrically conductive sense leads.
US11324539B2 Method of placing a bone implant in an operative position with respect to a bone part
The combination of: a) a bone implant having a body with a first portion that overlies an outer bone surface and first and second projections; and b) a bone implant handling instrument comprising: a guide assembly; and an implant advancing assembly. With a part of the bone implant handling instrument bearing against at least one bone part, the bone implant can be guided by the instrument in substantially a straight line in a first direction, while being maintained in substantially a same orientation with respect to the straight line, between a starting position and one operative position. The implant advancing assembly has at least one part that is movable against the bone implant to advance it into the operative position wherein the first and second projections are advanced into one or more bone parts and the first portion of the body overlies an outer bone surface. A method of placing the bone implant is also provided.
US11324538B2 Active bone plate
Disclosed herein are bone plates, bone plate systems, and methods of use thereof that can include a bone plate that includes a plate frame and first and second anvils. The plate frame can have a first surface and define a first opening and a second opening. Each of the first and second anvils can include first and second plates, and a body located in between the first and second plates. The first plate can have a first surface arranged to rest against the first surface of the plate frame when the bone plate is implanted. The second plate can be sized to pass into each of the first and second openings. The body can define a through hole sized to receive a fastener. When the bone plate is implanted, the plate frame can be moveable relative to the first and second anvils.
US11324529B2 Handheld surgical device having a rotating portion
A handheld surgical device with a working portion driven by a motor, wherein the working portion is contained in a concave-shaped portion when it is not activated, and the working portion becomes exposed from the concave-shaped portion when it is activated. The activation of the working portion can be controlled by a switch located at a handle portion of the handheld surgical device. The handheld surgical device includes a concave-shaped portion with a cutting edge, which is not driven by the motor.
US11324525B1 Surgical alignment guide assembly for total ankle replacement and method of using the same
A surgical guide assembly is disclosed herein that includes instruments configured to aid in the alignment of surgical instruments. In one aspect, a first and second instrument are provided that are configured to be connected to each other via interfaces and each define bone contact interface. The bone contact interfaces are configured to engage with the tibia and talus, in one embodiment.
US11324524B2 Foot and ankle surgical method and apparatus therefor
A weight-bearing stance corrected foot orthotic (12) is adapted to be used on the foot (2) of a anaesthetised patient in the supine or prone position, the weight bearing stance corrected foot orthotic (12) adapted to dorsiflex the toes of the forefoot of the patient an angle of between 30° to 50° to the plane of the foot (2). A surgical foot orthotic (12) is formed by the steps of disposing a patient's foot (2) or both feet in a weight bearing neutral position and dorsiflexing the forefoot or forefeet of the patient such that patient's foot (2) or feet are in or towards the Windlass configuration. A first orthotic (5) correcting the stance of the patient in the weight bearing position with dorsiflexed forefoot is formed and this is scanned to form an electronic image of the corrective load bearing surface. The electronic image is modified to include one or more guide apertures or cut-outs (9) and a surgical corrected weight-bearing orthotic from the modified electronic image is 3-D printed with the one or more guide apertures or cut-outs.
US11324522B2 Patient specific alignment guide with cutting surface and laser indicator
A patient-specific guiding system for guiding an instrument relative to a portion of an anatomical feature of a patient. The patient-specific guiding system includes a patient-specific guide. The guide includes a first portion having a first patient-specific inner surface that conforms to a first surface of the anatomical feature and an outer surface opposite the first patient-specific inner surface. The first portion also includes a guide surface for use in guiding the instrument relative to the anatomical feature. The guide also includes a second portion having a second patient-specific inner surface that conforms to a second surface of the anatomical feature and an outer surface opposite the second patient-specific inner surface. The second portion is removably connected to the first portion.
US11324513B2 Devices, systems, and methods for the treatment of vascular defects
Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, includes an occlusive device comprising a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising a first end portion, a second end portion, and a length extending between the first and second end portions, and a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges. The mesh may have a predetermined shape in the deployed state in which (a) the mesh is curved along its width, (b) the mesh is curved along its length, and (c) the mesh has an undulating contour across at least a portion of one or both of its length or its width. The mesh is configured to be positioned within the aneurysm in the deployed state such that the mesh extends over the neck of the aneurysm.
US11324512B2 Magnetic sphincter augmentation device for urinary incontinence
A sphincter augmentation device includes a plurality of bodies and a flexible band coupled with the bodies. The bodies define a first circumferential portion of the device and are magnetically biased toward one another. The flexible band defines a second circumferential portion of the device such that the bodies are arranged non-axisymmetrically about a central axis of the device. The device is sized to be positioned around a human urethra so that the bodies and the flexible band bear inwardly against the urethra. The device is configured to transition between a radially expanded state and a radially contracted state by the magnetic bias of the bodies to constrict the urethra.
US11324509B2 Spline crash correction with motor oscillation
A method for obviating spline crash in a surgical stapler that utilizes a motor of the surgical stapler includes oscillating an anvil retainer of the surgical stapler in a first oscillation pattern, oscillating the anvil retainer in a second oscillation pattern that is different from the first oscillation pattern after the first oscillation pattern, and retracting the anvil retainer until an anvil of the surgical stapler is in a clamped position relative to a shell assembly after the second oscillation pattern. Oscillating the anvil retainer in the first oscillation pattern includes oscillating the anvil retainer in a longitudinal direction between extension and retraction with the motor such that the anvil moves towards and away from the shell assembly. Oscillating the anvil retainer in the second oscillation pattern includes moving the anvil towards and away from the shell assembly.
US11324505B2 Reload assembly with spent reload indicator
A reload assembly is disclosed that includes a proximal body portion having an indicator that is movable from a retracted position to an advanced position to provides a visual indication to a clinician of the state of the reload assembly, i.e., whether the reload assembly is loaded with staples and ready for use or depleted of staples. A tool assembly of the presently disclosed reload assembly may also include a cartridge assembly, an anvil and a drive assembly. In embodiments, one or both of the cartridge assembly, the anvil, and/or the drive assembly may support an illuminating device. In embodiments, the illuminating device, which may be an LED, is adapted to change color when the reload assembly has been fired to provide an indication to a clinician that the reload assembly is spent. Since the illuminating device is illuminated when reload assembly is in both the unused and spent states, the illuminating device also improves visualization during placement and use of the reload assembly.
US11324504B2 Cartridge based lockout mechanism for right angle surgical stapler
A surgical stapler includes a body, a shaft assembly, and an end effector configured to receive a staple cartridge. The end effector is actuatable between an open state for receiving tissue and a closed state for clamping the tissue. A closure system operatively coupled with the end effector is operable to actuate the end effector from the open state to the closed state. A firing system operatively coupled with the end effector is actuatable to fire the end effector to staple and cut the clamped tissue. A lockout member operatively coupled with the closure system and the firing system is configured to inhibit actuation of the closure system to prevent closure of the end effector when an unspent staple cartridge is absent from the end effector. The lockout member is also configured to inhibit actuation of the firing system to prevent repeated firing with the same staple cartridge.
US11324503B2 Surgical firing member arrangements
A surgical stapling assembly is disclosed comprising a firing member comprising a vertically extending body portion comprising two lateral sides, a first jaw engagement member configured to slidably engage a first jaw as the firing member moves through a staple-firing stroke, and a second jaw engagement member extending laterally from each lateral side of the body portion, wherein the second jaw engagement member is configured to slidably engage a second jaw as the firing member moves through the staple-firing stroke. The second jaw engagement member comprises a vertical thickness and a lateral width defined as the distance between the body portion and an outer edge of the second jaw engagement member, wherein the vertical thickness and the lateral width comprise a ratio between about 1:2 and about 1:1.
US11324502B2 Surgical loading unit including an articulating end effector
A surgical loading unit includes an elongate body, an end effector pivotably coupled to the elongate body, and a flexible knife bar extending through a distal portion of the elongate body and a proximal portion of the end effector. Articulation of the end effector relative to the elongate body in a first direction moves a first segment of the knife bar in the first direction and moves a second segment of the knife bar in a second direction, opposite the first direction.
US11324499B2 Powered surgical instrument
A surgical instrument including a housing, an endoscopic portion, a shaft portion and an end effector is disclosed. The endoscopic portion extends distally from the housing and defines a longitudinal axis. The shaft portion is selectively connectable to a distal end of the endoscopic portion. The end effector is selectively connectable to a distal end of the shaft portion.
US11324494B2 Device and method for cutting-to-length surgical suture material
A device and method for cutting-to-length surgical suture material uses a thread spool having a continuous thread of the surgical suture material, a thread advancing gripper for drawing off a defined length of surgical suture material, and a cutting unit for cutting the surgical suture material. By way of a deflection installation, the surgical suture material is placeable so as to be angled to the primary transport direction in at least one open loop. The length of the open loop can be variably adjusted. The cutting unit is positioned between the thread spool and the deflection installation.
US11324492B2 Multifunctional surgical instrument
A multifunctional surgical instrument for extension of laparotomic, laparoscopic, robotic and thoracotomic incisions allows at the same time the spreading apart of the cutaneous/subcutaneous corners, pinching and lifting of the deep parietal layer, its dissection with the electrosurgical knife and protection of the surrounding and underlying tissues, particularly the intestinal ansae in the peritoneal cavity, during the dissection itself.
US11324490B2 Biopsy device tissue sample holder with removable tray
A biopsy device comprises a body, a needle, a cutter, and a tissue sample holder. The tissue sample holder comprises an outer cup and a cap. A tray retains severed tissue samples from a biopsy procedure. In some versions, the tray is selectively detachable from the cap in a one-handed operation by the user. The tray may be ejected into a sample container, such as a formalin cup. The cap may include a threaded portion that is configured to engage a complementary threaded portion of a sample container to seal the sample container once the tissue samples have been transferred to the sample container from the tissue sample holder of the biopsy device. One or more ports may be provided in the cap to manage excess fluid within the outer cup of the tissue sample holder, and/or to provide integrated access for a marker delivery device.
US11324488B2 Systems and methods of establishing a secondary connection at an ultrasound imaging machine, for providing access to an ultrasound image feed
The present embodiments relate generally to methods for providing viewing access to an ultrasound image feed generated at an ultrasound imaging machine. A multi-use display device may form a first link-layer connection with the ultrasound image machine for transmitting commands that control imaging parameters of the ultrasound image feed. The multi-use display device may then: determine link-layer connection parameters that allow the ultrasound imaging machine to form a second link-layer connection with a receiving device (the receiving device having no link-layer connection with the ultrasound imaging machine), and provide the connection parameters to the receiving device. The ultrasound imaging machine forms a second link-layer connection with the receiving device, based the connection parameters. The second link-layer connection is then used for receiving, at the receiving device, the ultrasound image feed controlled by the multi-use display device.
US11324485B2 Ultrasound imaging system with a neural network for deriving imaging data and tissue information
An ultrasound system according to some embodiments may include an ultrasound transducer configured to transmit ultrasound pulses toward tissue and generate echo signals responsive to the ultrasound pulses, a channel memory configured to store the echo signals, a beamformer configured to generated beamformed signals responsive to the echo signals, a neural network configured to receive one or more samples of the echo signals or the beamformed signals and produce a first type of ultrasound imaging data, and a processor configured to generate a second type of ultrasound imaging data, wherein the one or more processors may be further configured to generate an ultrasound image based on the first type of ultrasound imaging data and the second type of ultrasound imaging data and to cause a display communicatively coupled therewith to display the ultrasound image.
US11324482B2 Ultrasound diagnostic apparatus
An ultrasound diagnostic apparatus includes an ultrasound probe including a plurality of transducers arranged in a plurality columns and a switching element which switches input of a driving signal to the transducers and output of a receiving signal, a transmitter which outputs the driving signal to the transducers, a receiver which acquires the receiving signal corresponding to the transducers, and a hardware processor which generates ultrasound image data corresponding to each of the columns from the receiving signal, makes partial images in the ultrasound image data respectively have representations, synthesizes the ultrasound image data respectively including the partial images to generate composite image data, generates first identification information indicating to which position in a depth direction of the composite image data each of the representations of the partial images in the composite image data corresponds, and displays the generated first identification information and composite image data on a display.
US11324479B2 Shape injection into ultrasound image to calibrate beam patterns in real-time
A system for highlighting an instrument in an image includes a probe (122) for transmitting and receiving ultrasonic energy to and from a volume and a marker device (120) configured to respond to a received ultrasonic signal and emit an ultrasonic signal after a delay. The ultrasonic signal includes one or more pulses configured to generate a marker, when rendered, of a given size at a position within an image. A medical instrument (102) is disposed in the volume and includes the marker device. A control module (124) is stored in memory and is configured to interpret the ultrasonic energy received from the probe and from the marker device to determine a three dimensional location of the medical instrument and to highlight the three dimensional location of the marker device with the marker in the image.
US11324477B2 Multi-purpose instrument guide
An instrument guide (104) for a probe head (702) of an ultrasound imaging probe (106) that includes a transducer array (114) with a plurality of transducer elements (116) and an image plane. The instrument guide includes a probe support region (122) having a long axis (202) and configured to receive the probe head. The instrument guide further includes a first guide bracket (212) extending from a first side of the support region in a direction of the long axis. The instrument guide further includes a second guide bracket (230) extending from a second side of the support region in a direction transverse to the long axis. The instrument guide further includes a first guide (128) disposed in the first guide bracket. The instrument guide further includes a second guide (126) disposed in the second guide bracket.
US11324475B2 Handheld surgical devices with tactile operable controls
Disclosed are devices, systems and methods for providing sterile and cost-affordable handheld surgical devices with tactile operable controls. In some aspects, a surgical device includes a surgical probe including a probe detector and a set of operable controls; an exterior shell casing including an opening at one end leading to an interior cavity structured to have a size and shape to fit the surgical probe within and position the probe detector in a first region and a handle of the surgical probe in a second region, in which the first region of the exterior shell casing is configured to be inserted into an incision of a patient's body and the second region is configured to provide a user of the surgical device utilization of the operable controls of the surgical probe through the exterior shell casing; and a cap attachable to the exterior shell casing to close the opening.