Document Document Title
US11214833B2 Profiling microvesicle nucleic acids and uses thereof as signatures in diagnosis of renal transplant rejection
The invention relates generally to the use of microvesicle RNA signatures for diagnosis, predicting, and/or to monitor treatment efficacy, including patients who are candidates for renal transplant and/or who have received a renal transplant.
US11214823B2 Sample-to-answer system for microorganism detection featuring target enrichment, amplification and detection
The present invention relates to sample-to-answer systems, devices, cartridges, and method of using the same for detecting the presence of microorganisms in a sample, such as bacteria.
US11214819B2 Benzylisoquinoline alkaloids (BIA) producing microbes, and methods of making and using the same
Aspects of the invention include host cells that are engineered to produce benzylisoquinoline alkaloids (BIAs). The host cells include heterologous coding sequences for a variety of enzymes involved in synthetic pathways from starting compounds to BIAs of the host cell. Also provided are methods of producing the BIAs of interest by culturing the host cells under culture conditions that promote expression of enzymes encoded by the heterologous coding sequences of the host cells. Aspects of the invention further include compositions, e.g., host cells, starting compounds and kits, etc., that find use in methods of the invention.
US11214814B2 Transformed plant and flowering regulation method using flowering-inducing gene
Novel sugarcane-derived flowering-inducing genes each encoding a protein comprising the amino acid sequence of SEQ ID NO: 2 or 4 (the ScFT6 gene and the ScZCN16 gene), by which the flowering time is accelerated more slowly than conventionally known flowering-inducing genes, are provided.
US11214812B2 Cotton plant with seed-specific reduction in gossypol
A method is disclosed for reducing the level of gossypol in cottonseed. The method generally includes selectively inducing RNA gene silencing in the seed of a transgenic cotton plant, to interfere with expression of the δ-cadinene synthase gene or the δ-cadinene-8-hydroxylase gene in the seed of the cotton plant without substantially affecting expression of that gene in the foliage, floral parts, and roots of the plant. The transgenic cotton plant comprises at least one of a δ-cadinene synthase gene trigger sequence and/or a δ-cadinene-8-hydroxylase gene trigger sequence operably linked to one or more a seed-specific promoter gene sequences, and the trigger sequence(s) is/are able to induce RNA gene silencing when expressed in cottonseed of the plant. Also disclosed are expression cassettes, vectors, cells, seeds, and plants containing at least one of a δ-cadinene synthase gene trigger sequence and/or a δ-cadinene-8-hydroxylase gene trigger sequence operably linked to one ore more a seed-specific promoter DNA sequences.
US11214802B2 RNAi agents for inhibiting expression of alpha-ENaC and methods of use
Described are RNAi agents, compositions that include RNAi agents, and methods for inhibition of an alpha-ENaC (SCNN1A) gene. The alpha-ENaC RNAi agents and RNAi agent conjugates disclosed herein inhibit the expression of an alpha-ENaC gene. Pharmaceutical compositions that include one or more alpha-ENaC RNAi agents, optionally with one or more additional therapeutics, are also described. Delivery of the described alpha-ENaC RNAi agents to epithelial cells, such as pulmonary epithelial cells, in vivo, provides for inhibition of alpha-ENaC gene expression and a reduction in ENaC activity, which can provide a therapeutic benefit to subjects, including human subjects.
US11214801B2 RNAi agents and compositions for inhibiting expression of apolipoprotein C-III (APOC3)
The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, capable of inhibiting Apolipoprotein C-III (also called APOC3, apoC-III, APOC-III, and APO C-III) gene expression, and compositions that include APOC3 RNAi agents. The APOC3 RNAi agents disclosed herein may be conjugated to targeting ligands, including ligands that include N-acetyl-galactosamine, to facilitate the delivery to cells, including to hepatocytes. Pharmaceutical compositions that include one or more APOC3 RNAi agents, optionally with one or more additional therapeutics, are also described. Delivery of the APOC3 RNAi agents in vivo provides for inhibition of APOC3 gene expression, and can result in lower triglycerides and/or cholesterol levels in the subject. The APOC3 RNAi agents can be used in methods of treatment of APOC3-related diseases and disorders, including hypertriglyceridemia, cardiovascular disease, and other metabolic-related disorders and diseases.
US11214800B2 Methods and compositions for altering function and structure of chromatin loops and/or domains
Chromatin 3D structure modulating agents in the context of the present invention are intended to interfere or manipulate the function of loop anchor motifs, such as CTCF motifs. In certain example embodiments, the present invention may block formation of an loop anchor or chromatin domain or induce formation of a loop anchor or chromatin domain at a targeted genomic location. For instance, a loop anchor motif can be altered, such as by mutating (including inverting) a binding motif so as to remove such a motif, or by adding new binding motifs in new locations within a loop domain, so as to reduce the size of an existing loop, so as to modify the size of an existing loop, or combinations thereof. Alternatively, the chromatin 3D structure modulating agent may bind a target region and mask a loop anchor motif, thereby preventing a loop anchor or chromatin domain from forming. The chromatin 3D structure modulating agent may bind a target region and cause a loop anchor of chromatin domain to form.
US11214789B2 Concentration and washing of particles with acoustics
Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the multi-stage acoustophoretic devices are also disclosed. The systems may include multiple acoustophoretic devices fluidly connected to one another in series, each acoustophoretic device comprising a flow chamber, an ultrasonic transducer capable of creating a multi-dimensional acoustic standing wave, and a reflector. The systems can further include pumps and flowmeters.
US11214788B2 Tripterygium wilfordii cryptomeridiol synthase, coding gene thereof and recombinant yeast containing coding gene
Provided are a Cryptomeridiol synthase and a coding gene thereof. Also provided are a Cryptomeridiol synthase and a coding gene, a engineered yeast containing the Cryptomeridiol coding gene, and a use of same in plant breeding and biosynthesis. The cDNA full-length sequence of the Cryptomeridiol synthase gene in Tripterygium wilfordii is obtained by means of polymerase chain reaction cloning. Then, by means of synthetic biology, the engineered yeast containing the Cryptomeridiol synthase gene is constructed to realize the production of Cryptomeridiol in the yeast.
US11214786B2 Penicillin-G acylases
The present invention provides engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes.
US11214784B2 Cysteine protease
The present invention relates to a novel polypeptide which displays IgG cysteine protease activity, and in vivo and ex vivo uses thereof. Uses of the polypeptide include methods for the prevention or treatment of diseases and conditions mediated by IgG, and methods for the analysis of IgG.
US11214780B2 Nucleobase editors and uses thereof
Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing proteins or protein domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing proteins or domains, are provided.
US11214779B2 Activatable CRISPR/CAS9 for spatial and temporal control of genome editing
Disclosed herein is a genetically encoded light- or chemically-activated Cas9 engineered through the site-specific installation of an activatable lysine amino acid. Such activatable Cas9 proteins can be used in CRISPR/Cas9 systems to control gene expression temporally, spatially, or both. Systems, methods, kits, and compositions for manipulation of sequences and/or activities of target sequences are provided. Also provided are methods of directing CRISPR complex formation in cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR/Cas9 system.
US11214773B2 Antibacterial and protective bacteriophage formulations and methods for making and using them
In alternative embodiments, provided are compositions comprising chemically or structurally modified bacteriophages of the genus Caudovirales having an exterior or outer surface comprising at least one heterologous carbohydrate binding domain (CBD) comprising a lectin or a plurality of additional homologous CBDs, or more CBDs than found on a comparable wild type (WT) bacteriophage.
US11214772B2 Production method for retinal tissue
The present invention provides a method for producing retinal cells or a retinal tissue, comprising the following steps (1)-(3): (1) a first step of culturing human pluripotent stem cells in the absence of feeder cells and in a medium comprising a factor for maintaining undifferentiated state, (2) a second step of culturing the pluripotent stem cells obtained in the first step in suspension in the presence of a Sonic hedgehog signal transduction pathway activating substance to form a cell aggregate, and (3) a third step of culturing the aggregate obtained in the second step in suspension in the presence of a 1) a BMP signal transduction pathway activating substance to obtain an aggregate containing retinal cells or a retinal tissue.
US11214768B2 Methods of generating functional human tissue
Methods of tissue engineering, and more particularly methods and compositions for generating various vascularized 3D tissues, such as 3D vascularized embryoid bodies and organoids are described. Certain embodiments relate to a method of generating functional human tissue, the method comprising embedding an embryoid body or organoid in a tissue construct comprising a first vascular network and a second vascular network, each vascular network comprising one or more interconnected vascular channels; exposing the embryoid body or organoid to one or more biological agents, a biological agent gradient, a pressure, and/or an oxygen tension gradient, thereby inducing angiogenesis of capillary vessels to and/or from the embryoid body or organoid; and vascularizing the embryoid body or organoid, the capillary vessels connecting the first vascular network to the second vascular network, thereby creating a single vascular network and a perfusable tissue structure.
US11214764B2 Cleaning and/or rinsing agent molded article
The present invention relates to a cleaning and/or rinsing agent molded article (1, 1′, 1″) which is formed as a roller with a roll surface (2) and comprises two end faces (3, 4) connected by the roll surface (2). The cleaning and/or rinsing agent molded article (1, 1′, 1″) comprises an end face portion (5, 6) on at least one of the two end faces (3, 4), which is designed so that the cleaning and/or rinsing agent molded article (1, 1′, 1″) falls sideways onto the roll surface (2) when the cleaning and/or rinsing agent molded article (1, 1′, 1″) meets the relevant end faces (3, 4) or is placed against a solid surface. A cleaning product comprises a pouch, in which a cleaning and/or rinsing agent molded article of this type is located. A cleaning product (10) is also described, comprising a sealed pouch (11) in which a cleaning and/or rinsing agent molded article (1, 1′, 1″) of this type is located. Also described is the use of a cleaning and/or rinsing molded article (1, 1′, 1″) of this type for cleaning the interior of an appliance and a method for cleaning the interior of an appliance, more particularly an industrial cooking appliance (100) using the cleaning and/or rinsing agent molded article (1, 1′, 1″). Finally described are a method and a device for the production of a cleaning and/or rinsing agent molded article (1, 1′, 1″) of this type.
US11214760B2 Detergent composition
The present invention concerns a detergent and a pharmaceutical composition comprising a deoxyribonuclease (DNase), wherein the DNase is obtained from a fungal source. It further concerns a laundering method and the use of DNase. The present invention further relates to polypeptides having DNase activity, nucleotides encoding the polypeptide, as well as methods of producing the polypeptides.
US11214752B2 Lubricant composition containing copolymers of polyisobutylenemethacrylate
The present invention is directed to the use of poly(polyisobutylenemethacrylate) as viscosity index improving component in lubricating oil compositions. The invention is further related to lubricating oil compositions comprising poly(polyisobutylenemethacrylate) with enhanced shear stability.
US11214750B2 Combinations of phosphorous-containing compounds for use as anti-wear additives in lubricant compositions
The present disclosure relates to a lubricant composition comprising a first phosphorus compound, a second phosphorus compound, and a third phosphorus compound, wherein the first phosphorus compound is present in the lubricant composition in an amount to provide between about 120 and 350 ppm phosphorus. The lubricant composition may provide robust anti-wear and reduced pitting.
US11214747B2 Multi-functional foam concentrate-type agent for inhibiting spontaneous ignition of soft coal
The present invention relates to a multifunctional spontaneous combustion inhibitor for bituminous coal in the form of a foam concentrate, which may inhibit the spontaneous combustion of bituminous coal, prevent the scattering of bituminous coal, prevent the occurrence of problems due to spontaneous combustion, such as a power plant operation failure, bituminous coal waste, and odor generation, enables a bituminous coal power plant to be operated economically, safely and environmentally friendlily through the use of inexpensive bituminous coal, and may be used even at −20° C. by improving the pour point thereof. The present invention is characterized in that a spontaneous combustion inhibitor is prepared in the form of a water-soluble foam concentrate by using an antioxidant, a volatile fraction activation inhibitor, and an emulsifier compound, is mixed with water and air, and is distributed and applied to bituminous coal in a foamed state.
US11214746B2 Power generation system
A power generation system comprises a fuel gas supply device 13 for controlling methane concentration or carbon dioxide concentration in a mixed gas MG containing methane and carbon dioxide within a setting range for the concentration in the fuel gas of a gas engine 11, and for supplying the mixed gas MG to the gas engine 11 as the fuel gas, and a gas concentration sensor 14 for measuring the carbon dioxide concentration or the methane concentration of the mixed gas MG. The fuel gas supply device 13 comprises a carbon dioxide removal device 16 for removing carbon dioxide in the mixed gas MG, and an operating condition control device 17 for controlling an operating condition that affects an increase or decrease of a carbon dioxide removal rate of the carbon dioxide removal device 16, and the operating condition control device 17 controls the operating condition of the carbon dioxide removal device 16 based on the measurement result of the gas concentration sensor 14, thereby controlling the concentration of methane and carbon dioxide in the mixed gas.
US11214744B2 Fuel compositions from light tight oils and high sulfur fuel oils
Methods are provided to prepare a low sulfur fuel from hydrocarbon sources, such as light tight oil and high sulfur fuel oil, often less desired by conventional refiners, who split crude into a wide range of differing products and may prefer presence of wide ranges (C3 or C5 to C20 or higher) of hydrocarbons. These fuels can be produced by separating feeds into untreated and treated streams, and then recombining them. Such fuels can also be formulated by combinations of light, middle and heavy range constituents in a selected manner as claimed. Not only low in sulfur, the fuels of this invention are also low in nitrogen and essentially metals free. Fuel use applications include on-board large marine transport vessels but also on-shore for large land based combustion gas turbines, boilers, fired heaters and transport vehicles and trains.
US11214741B2 Fluid catalytic cracking process for cracking multiple feedstocks
A fluid catalytic cracking (FCC) process for cracking multiple feedstocks in a FCC apparatus comprising a first set of feed distributors having first distributor tips and a second set of feed distributors having second distributor tips is provided. A first feed is injected into the riser from first distributor tips. A second feed is injected into the riser from second distributor tips. The first distributor tips and the second distributor tips are positioned at different radii in the riser. The first feed and the second feed are cracked in the riser in the presence of an FCC catalyst to provide a cracked effluent stream. The first distributor tips and the second distributor tips are located into a region of lower catalyst density and a region of higher catalyst density respectively in the riser.
US11214739B2 Method and system for dynamically charging a coke oven
Systems and methods of dynamically charging coal in coke ovens related to the operation and output of coke plants including methods of automatically charging a coke oven using a charging ram in communication with a control system to increase the coke output and coke quality from coke plants. In some embodiments, the control system is capable of moving the charging ram in a horizontal first direction, a horizontal second direction and a vertical third direction while charging coal into the oven. In some embodiments, the coal charging system also includes a scanning system configured to scan an oven floor to generate an oven floor profile and/or oven capacity. The scanning system used in combination with the control system allows for dynamic leveling of the charging ram throughout the charging process. In some embodiments, the charging ram includes stiffener plates and support members to increase the mechanical strength of the charging ram and decrease the sag of the charging ram at a distal end.
US11214733B2 Surface-passivated quantum dots and method for passivating surface of quantum dots
The present invention provides a quantum dot of which a surface is passivated with a short chain ligand, and a method of passivating a surface of the quantum dot using a ligand exchange reaction.
US11214729B2 Re-crosslinking particle gel for CO2 conformance control and CO2 leakage blocking
The present invention generally relates to the composition of particle gels for CO2-EOR and CO2 storage. More particularly, CO2 resistant particle gels are provided that can re-crosslink at subterranean conditions. These particle gels can be deployed to improve the conformance of CO2 flooding, CO2 huff-puff, or Water-Alternative-Gas (WAG). The applications may also involve CO2 storage, such as the blocking of CO2 leakage and similar CO2 processing.
US11214728B2 Modified MoS2 nano material, and preparation method and use thereof
The invention provides a modified MoS2 nano material and a preparation method thereof. The modified MoS2 nanomaterial is comprised of a hydrophilic MoS2 nanosheet linked with hydrophobic alkyl amine chain, the hydrophobic alkyl amine chain is provided by an alkylamine compound. The modified MoS2 nano material provided by the invention can be formulated into a nanofluid i.e. oil-displacement agent at a lower concentration, and is applied to the tertiary recovery in oil recovery, thereby greatly reducing the environmental pollution in the tertiary recovery, reducing the cost and improving the oil recovery.
US11214726B2 Compositions for drilling applications
Certain examples described herein are directed to a foaming agent for utilization in drilling that has greater environmental desirability due to the elimination of molecular ammonia and ammonium ion and further, has the added feature of greater economy while maintaining nominal to superior functioning in the capacity of lifting and performing at characteristic operating temperature. In some configurations, the compositions may desirably omit toxic or flammable substances to include lighter alcohols, and or environmentally persistent components. Further, various embodiments can achieve an improved level of foam stability.
US11214723B2 Super concentrate additive solution composition
A super concentrate additive solution is disclosed herein. A super concentrate additive solution can be added into a heat transfer fluid to improve corrosion protection performance and to extend the service life of a heat transfer system or the fluids therein. A method includes adding a super concentrate additive solution to a heat transfer fluid to form a super additive heat transfer fluid and adding the mixture to a heat transfer system. A super concentrate additive solution can also be used in flexible production of a high corrosion protection performance heat transfer fluid concentrate, pre-diluted heat transfer fluids, or ready-for-use heat transfer fluids.
US11214721B2 Thermally conductive composite silicone rubber sheet and method for manufacturing same
Provided is a thermally conductive composite silicone rubber sheet formed by laminating an acrylic pressure-sensitive adhesive layer on one side of a non-pressure-sensitive adhesive/high-hardness thermally conductive silicone rubber sheet, wherein the acrylic pressure-sensitive adhesive layer is a cured product of an acrylic pressure-sensitive adhesive composition containing: an acrylic pressure-sensitive adhesive made of a polymer of a monomer mixture in which 5-50 mol % of hydroxyl group-containing monomers are contained in all of the constituent monomers; and 0.05-5 parts by mass of a chelate-based curing agent with respect to 100 parts by mass of the acrylic pressure-sensitive adhesive, and the thermally conductive silicone rubber sheet has a thermally conductive silicone rubber layer which, as a cured product of a thermally conductive silicone composition containing a thermally conductive filler, has a durometer A hardness of 60-96.
US11214716B2 Phenol-based resin adhesive from lignin pyrolysis and its preparation method
The present invention relates to a phenol-based resin adhesive from lignin pyrolysis, comprising a polymer of phenol and formaldehyde from lignin pyrolysis, wherein the phenol from lignin pyrolysis comprises at least two phenols from lignin pyrolysis or at least two lignin-modified phenols from lignin pyrolysis. A repeat unit of the polymer of phenol and formaldehyde from lignin pyrolysis comprises at least two phenol units from lignin pyrolysis or at least two lignin-modified phenol units from lignin pyrolysis. According to the phenol-based resin adhesive from lignin pyrolysis in the present invention, by-products during the pyrolysis of lignin for power generation are used as raw materials, so it is environment-friendly and economical.
US11214707B2 Compositions and methods for fabricating coatings
Aspects of the present disclosure provide coatings and methods for depositing coatings onto surfaces. In one aspect, a method for forming a coating includes applying a composition to a surface of a component, the composition including a first polymer, a second polymer that is a fluoropolymer, an isocyanate, and a curative. The method includes curing the mixture at a first temperature of about 50° C. or greater and increasing the first temperature to a second temperature of about 80° C. or greater. The method includes obtaining a coating disposed on the surface of the component, the coating having a thickness of from about 10 mils to about 50 mils and a void density of less than 5 voids of size 0.5 mm or greater per cm2.
US11214703B2 Coating compositions comprising a silane modified compound
A coating composition comprising an acid functional acrylic resin and a silane modified compound is disclosed. Substrates coated at least in part with such coatings are also disclosed.
US11214702B2 Black coloring composition
The present application relates to the field of black coloring of materials made from wood, such as reconstituted wood panels or paper/cardboard. The black coloring composition for wood-based materials includes a black pigment, a reactive type black dye and water. It is also possible to prepare a dry extract for some special applications.
US11214701B2 Compositions and methods including depositing nanomaterial
An ink composition including a nanomaterial and a liquid vehicle, wherein the liquid vehicle includes a composition including one or more functional groups that are capable of being cross-linked is disclosed. An ink composition including a nanomaterial, a liquid vehicle, and scatterers is also disclosed. An ink composition including a nanomaterial and a liquid vehicle, wherein the liquid vehicle includes a perfluorocompound is further disclosed. A method for inkjet printing an ink including nanomaterial and a liquid vehicle with a surface tension that is not greater than about 25 dyne/cm is disclosed. In certain preferred embodiments, the nanomaterial includes semiconductor nanocrystals. Devices prepared from inks and methods of the invention are also described.
US11214696B2 Multilayer structure and method for producing same, coating liquid, packaging material, and protective sheet for electronic devices
The present invention relates to a multilayer structure including a base (X) and a layer (Y), wherein the layer (Y) includes an aluminum-containing compound (A) and a phosphorus compound (BH) in which a phosphorus atom having at least one hydroxy group and a polar group are bonded via an alkylene chain having 3 to 20 carbon atoms or a polyoxyalkylene chain based on an alkylene having 3 to 20 carbon atoms, and the aluminum-containing compound (A) is a compound (Ab) including a reaction product (D) of an aluminum-containing metal oxide (Aa) and an inorganic phosphorus compound (BI).
US11214693B2 Electrically conductive coating compositions with corrosion resistance
An electrically conductive and corrosion resistant graphene-based coating composition, including a binder, a graphene-filler; and a dispersing agent, wherein the graphene filler comprises a plurality of graphene stacks.
US11214689B2 High chroma flakes
An article including a reflector having a first surface and a second surface opposite the first surface; a first selective light modulator layer external to the first surface of the reflector; a second selective light modulator layer external to the second surface of the reflector; a first absorber layer external to the first selective light modulator layer; and a second absorber layer external to the second selective light modulator layer; wherein each of the first and second selective light modulator layers include a host material is disclosed herein. Methods of making the article are also disclosed.
US11214687B2 Small-molecule organic dyes
The present invention relates to compounds of formula (A), wherein Z is NR10 or O. These compounds represent novel acridinium and xanthylium salts having an unprecedented substituted heterocyclic core. They are useful as fluorescent dyes or precursors thereof in different applications including various imaging and sensing techniques, and, in particular, as photosensitizers and hereby preferably as photocatalysts. The present invention further relates to processes for preparing the inventive compounds via 1,5-organodimetallic reagents from double directed ortho-metalation reactions or combined halogen-metal exchange/directed ortho-metalation reactions.
US11214686B2 Oxygen scavenging polyester compositions for containers
Disclosed herein is an oxygen scavenging composition for containers. The oxygen scavenging composition for containers may comprise at least one polyester component, a transition metal catalyst, an oxygen scavenger, and a vegetable oil. The vegetable oil preferably comprises at least one molecule having a double allylic structure. The polyester component preferably comprises at least one acid unit and at least one diol unit. The concentration of double allylic structures of the vegetable oil in the composition may be greater than 5.0 meq/kg of all of the polyester components. The oxygen scavenger is preferably present in the composition at a level less than 1.0% by weight of the total composition. The vegetable oil is preferably present in the composition at a level greater than 0.3% by weight relative to the total weight of the polyester components, the transition metal catalyst and the vegetable oil.
US11214685B2 Curable organopolysiloxane composition and cured product thereof
A curable organopolysiloxane composition is provided. The curable organopolysiloxane composition comprises: (A) a diorganopolysiloxane having at least two silicon-bonded alkenyl groups per molecule; (B) an organopolysiloxane resin; (C) a mixture of (C1) a diorganopolysiloxane endblocked with silicon-atom bonded hydrogen atoms at both molecular terminals and (C2) an organohydrogenpolysiloxane having at least three silicon-bonded hydrogen atoms per molecule; (D) a polyether having at least one aliphatic unsaturated group per molecule; and (E) a hydrosilylation catalyst.
US11214684B2 Carboxylated vinyl acetate/ethylene copolymer dispersions and uses therof
The present invention relates to preparation of heterogeneous mixtures of (carboxylated) vinyl ester/ethylene dispersions, such as vinyl acetate/ethylene (VAE) dispersions with polyamideamine-epichlorohydrin (PAE) wet strength resins having a reduced amount of halogenated organic compounds, such as less than 1500 ppm. The dispersion offers extremely low free and bound formaldehyde levels combined with wet tensile strength for use in non-woven textile and paper applications.
US11214680B2 Polybutylene terephthalate resin composition and molded article
A polybutylene terephthalate resin composition containing a polybutylene terephthalate resin, a silicone-based compound having a kinematic viscosity at 25° C. of 1,000 to 10,000 cSt in an amount of 0.5 to 1.8% by mass of the total mass of the polybutylene terephthalate resin composition, and an olefin-based elastomer in an amount of 5 to 20% by mass of the total mass of the polybutylene terephthalate resin composition.
US11214679B2 High strength sheet molding composition formed with an interpenetrating polymer network
A polyurea additive is provided that strengthens a given base sheet molding composition (SMC) An isocyanate containing species and an amine containing species are introduced into an uncured polymeric resin of a sheet molding compound (SMC) under conditions suitable for the formation of a polyurea polymer network. Upon cure of the SMC base resin, an interpenetrating network is formed that is stronger than the base SMC absent the polyurea. As a result, an article is formed from the SMC that is stronger at the same dimensions than a conventional article or thinned to achieve the same properties to obtain a lightweight article compared to that formed from conventional SMC. The properties of the article are also attractive relative to aluminum for the formation of vehicle body and exterior panels.
US11214675B2 Aqueous binder composition
The present invention relates to a process for preparing an aqueous binder composition, as well as the aqueous binder composition comprising a carboxylic acid-functional vinyl polymer (polymer A) and vinyl polymer (polymer B).
US11214667B2 Pneumatic tire
The present invention is directed to a pneumatic tire having a tread comprising a vulcanizable rubber composition comprising, based on 100 parts by weight of elastomer (phr), (A) from about 20 to about 100 phr of a solution polymerized styrene-butadiene rubber having a glass transition temperature (Tg) ranging from −85° C. to −50° C.; (B) from 0 to about 40 phr of a natural rubber or synthetic polyisoprene; (C) from 0 to about 30 phr of cis-1,4 polybutadiene having a Tg of from −110° C. to −90° C.; (D) from 0 to 50 phr of a process oil; (E) from 20 to 80 phr of a hydrocarbon resin having a Tg of at least 30° C.; and (F) from 90 to 150 phr of silica.
US11214665B2 Polymerization initiator composition, preparation method therefor, and method for preparing polymer using same
A polymerization initiator composition includes isomers of the polymerization initiator, thereby preventing instability and inertness of the polymerization initiator and physical property degradation of the SSBR, minimizing by-products and unreacted materials, and remarkably improving a conversion ratio. In addition, when the polymerization initiator composition according to the present invention is used, there is no need to add a polar additive separately upon polymer polymerization, since the polar additive is already added at the time of preparing the polymerization initiator. Further, the polymer initiator composition has high polarity so that the hydrophobic SSBR and the hydrophilic silica can be effectively dispersed.
US11214663B2 Method and system for making light-blocking articles
A method is designed to prepare foamed, opacifying elements each having a target light blocking value (LBVT) of at least 3, using a textile fabric substrate with a light blocking value (LBVS). The LBVT-S difference is calculated; a foamable aqueous composition is chosen; a dry coating weight for the foamable aqueous composition (when foamed) is determined to form a single dry opacifying layer that is foamed, dried, and densified to provide a dry thickness at least 20% less than the original dry thickness. The single dry opacifying layer a has light blocking value that is equal to LBVT-S, ±15%. The desired foamable aqueous composition can be chosen from a set of similar compositions to achieve the desired LBVT with the noted textile fabric substrate using suitable mathematical formula relating dry coating weight to light blocking value and a suitable data processor.
US11214661B2 Three-dimensional nanofabrication by patterning of hydrogels
The present invention enables three-dimensional nanofabrication by isotropic shrinking of patterned hydrogels. A hydrogel is first expanded, the rate of expansion being controlled by the concentration of the crosslinker. The hydrogel is then infused with a reactive group and patterned in three dimensions using a photon beam through a limited-diffraction microscope. Functional particles or materials are then deposited on the pattern. The hydrogel is then shrunk and cleaved from the pattern.
US11214660B2 Prepreg, laminate, printed wiring board, coreless substrate, semiconductor package and method for producing coreless substrate
The present invention relates to a prepreg including a fiber base material layer containing a fiber base material, a first resin layer formed on one surface of the fiber base material layer, and a second resin layer formed on the other surface of the fiber base material layer, wherein the first resin layer is a layer obtained through layer formation of a resin composition (I) containing, as a main component of resin components, an epoxy resin (A), and the second resin layer is a layer obtained through layer formation of a resin composition (II) containing, as a main component of resin components, an amine compound (B) having at least two primary amino groups in one molecule thereof and a maleimide compound (C) having at least two N-substituted maleimide groups in one molecule thereof; a laminated sheet obtained by using the prepreg; a printed wiring board; a coreless board; a semiconductor package; and a method of producing a coreless board.
US11214655B2 Method of crosslinking glycosaminoglycans
A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.
US11214654B2 Nanocomposite hydrogel, and preparation method and use thereof
The present invention provides a nanocomposite hydrogel and a preparation method thereof, and relates to the field of nanocomposite materials. The nanocomposite hydrogel is prepared by mixing completely gelatinized short amylose with an aqueous gelatin solution having a mass concentration of 8%-14%, and then cooling. The present invention utilizes the nanoparticles formed by in-situ self-assembly of the short amylose in the aqueous gelatin solution as a reinforcing agent, and the nanoparticles are uniformly distributed in the hydrogel to form a stable crystallization system, such that the prepared nanocomposite hydrogel exhibits optimal mechanical properties in terms of viscoelasticity, hardness, compressive stress, etc. The preparation process of the present invention is green and environmentally friendly, simple and efficient, and can be widely applied to the fields of food, cosmetics and medicine.
US11214647B2 Process for producing a low density free-rise polyurethane foam
There is described a process for producing a free-rise polyurethane foam having a density of less than or equal to about 0.75 pcf. the process comprises the steps of: (a) contacting: (i) an isocyanate, (ii) a first polyol comprising a first polymer chain consisting essentially of propylene oxide units and alkylene oxide units selected from ethylene oxide, butylene oxide and mixtures thereof in a weight ratio of propylene oxide units to alkylene oxide units in the range of from about 90:10 to about 25:75, the polymer chain being terminally capped with the ethylene oxide units, the first polyol having a primary hydroxyl content of at least about 70% based on the total hydroxyl content of the first polyol, (iii) water (iv) a surfactant and (v) a catalyst to form a foamable reaction mixture; and (b) expanding the foamable reaction mixture to produce the free-rise polyurethane foam.
US11214642B2 Liquid crystal elastomers
Shape-programmable liquid crystal elastomers. The shape-programmable liquid crystal elastomers being synthesized by filling an alignment cell with liquid crystal monomers. The liquid crystal monomers align to a surface of the alignment cell and then are polymerized with a dithiol chain transfer agent. The alignment cell is configured to impose a director orientation on a portion of the shape-programmable liquid crystal elastomer. For some embodiments, liquid crystal elastomer laminates are prepared by arranging a plurality of liquid crystal elastomers such that a director orientation of each liquid crystal elastomer of the plurality is in registered alignment with an adjacent liquid crystal elastomer of the plurality. The arrangement is secured and the plurality of liquid crystal elastomers cured.
US11214641B2 Thickening anionic copolymer
The invention relates to a copolymer obtained by polymerisation reaction of at least three comonomers: a first anionic monomer, a second monomer comprising an olefin unsaturation, and a third monomer comprising a hydrophobic group. The invention likewise relates to the use of said copolymer as a thickening agent, in particular in aqueous suspensions of mineral particles with high solids content. The copolymer according to the invention makes it possible to improve the compromise between viscosity with high shear gradient and viscosity with low shear gradient, while also improving water retention inside the suspension.
US11214640B2 Processing aids and polymer formulations containing the same and method for producing the same
A multi-stage emulsion processing aid polymer comprising one or more functionalized ethylenically unsaturated monomer into the emulsion polymerization reactor, wherein the functionality is selected from the group consisting of β-keto esters, β-keto amides, β-diketones, cyanoacetic esters, malonates, nitroalkanes, β-nitro esters, sulfonazides, thiols, thiol-s-triazines, and amine, where the functionality is incorporated into polymers by polymerizing, ethylenically unsaturated monomers containing these functionalities or by post functionalization of a polymer with additional reactions after polymerization in one of the first or second stages. Foamable halogenated polymers comprising the multi-stage emulsion processing aid polymer is also provided. Also provided are methods for making the multi-stage emulsion processing aid polymer and foamable halogenated polymers.
US11214639B2 Copolymer, rubber composition, resin composition, tire and resin product
An object of the present disclosure is to provide a copolymer excellent in fracture resistance, ozone resistance and wear resistance. In order to achieve the object, the present disclosure provides a copolymer containing at least an ethylene unit, a C4-10 non-conjugated olefin unit and a conjugated diene unit, wherein a content of 3,4 or 1,2-vinyl bond in the conjugated diene unit is equal to or larger than 30 mol %.
US11214638B2 Method for producing highly reactive polybutene
A method for preparing polybutene by polymerization of a raw material of a carbon number 4 (C4) compounds having an isobutene amount of 50 to 75% by weight, is disclosed. The raw material of C4 compounds is selected from the group consisting of (a) C4 compound material obtained by adding high purity isobutene to C4 raffinate-1; (b) C4 compound material obtained by adding high amount isobutene mixture which is generated in an olefin conversion unit (OCU) process to C4 raffinate-1; (c) C4 compound material obtained by adding high purity to butane-butene oil (B-B oil); (d) C4 compound material obtained by adding high amount isobutene mixture which is generated in an olefin conversion unit (OCU) process to butane-butene oil (B-B oil); (e) C4 compound material obtained by adding a dilute solvent to high purity isobutene; (f) C4 compound material obtained by adding a dilute solvent to high amount isobutene mixture which is generated in an olefin conversion unit (OCU) process; (g) C4 compound material obtained by adding high purity isobutene to a mixture generated in dehydrogenation reaction that converts isobutane to isobutene; and (h) C4 compound material obtained by adding high amount isobutene mixture which is generated in an olefin conversion unit (OCU) process to a mixture generated in dehydrogenation reaction that converts isobutane to isobutene.
US11214637B2 Processes for making polyisobutylene compositions
Methods of making polyisobutylene and catalyst systems are described. Polyisobutylene compositions and catalyst system compositions are also described. In some embodiments, a method of making a catalyst system includes: providing a support material; calcining the support material; and forming a catalyst system by adding to the support material (a) a mixture comprising BF3, (b) a mixture comprising BF3 and a complexing agent, or (c) both. In some embodiments, a method of making a polymer composition includes providing a catalyst system comprising: (a) a support material selected from the group consisting of Al2O3, ZrO2, TiO2, SnO2, CeO2, SiO2, SiO2/Al2O3, and combinations thereof; and (b) BF3; providing a feedstock comprising isobutylene; forming a reaction mixture comprising the feedstock and the catalyst system; contacting the isobutylene with the catalyst system; and obtaining a polymer composition.
US11214636B2 Rigid non-cyclopentadienyl group 4 transition metal and rare earth metal catalysts for olefin polymerization
The present application provides a catalyst component for alkene polymerization. The catalyst component contains: (a) a group 4 transition metal or rare earth metal, (b) a rigid non-cyclopentadienyl ligand with a tricyclic backbone composed of three ortho-fused 6-membered rings in a linear arrangement (as is the case in xanthene), with or without additional fused rings; the tricyclic backbone contains at least one donor atom within the central ring (as is the case for xanthene, oxanthrene, or acridan); furthermore, donor atoms/groups or aryl rings are attached directly (i.e. via the donor atom in the case of donor groups) to both of the bondable carbon atoms adjacent to at least one of the donor atoms within the central ring (e.g. xanthene with two donor groups, or two aryl rings, or one donor group and one aryl ring adjacent to oxygen), and (c) two or more activatable ligands, such as chloro, alkyl, aryl, allyl or hydride ligands, attached to the central metal if the complex is neutral or anionic, or one or more activatable ligand if the complex is monocationic or dicationic. The rigid non-cyclopentadienyl ligand has a charge of 0, 1- or 2- (considering all donor atoms of the ligand to have an octet of valence electrons). The catalyst component is optionally combined with an activator, typically for the purpose of generating a highly active monocationic or dicationic polymerization catalyst, and the catalyst and/or catalyst components may be in solution, precipitated from solution, or optionally carried on a support.
US11214634B2 Lewis base catalysts and methods thereof
The present disclosure relates to Lewis base catalysts. Catalysts, catalyst systems, and processes of the present disclosure can provide high temperature ethylene polymerization, propylene polymerization, or copolymerization as the Lewis base catalysts can be stable at high polymerization temperatures and have good activity at the high polymerization temperatures. The stable catalysts with good activity can provide formation of polymers having high melting points, high isotacticity, and controllable molecular weights, and the ability to make an increased amount of polymer in a given reactor, as compared to conventional catalysts. Hence, the present disclosure demonstrates highly active catalysts capable of operating at high reactor temperatures while producing polymers with controlled molecular weights and or robust isotacticity.
US11214630B2 Process for preparing a (meth)acrylate additive, a method of improving the sag resistance of a polyolefin and a sag resistant polyolefin
A process for preparing a (meth)acrylate comprising preparing an aqueous phase by combining water, one or more stabilizing agents, and one or more surfactants; preparing an oil phase by combining one or more free radical initiators, one or more monomers capable of undergoing radical polymerization, one or more crosslinking and/or graft-linking monomers, and stearyl methacrylate and/or lauryl methacrylate, wherein the free radical initiator is capable of partitioning preferentially into the oil phase; combining the aqueous and oil phases and mixing to form a suspension having oil droplets ranging in size from 1 to 10 microns; raising the temperature of the suspension to effect an initial polymerization forming a core polymer is provided.
US11214629B2 Method for preparing short-clustered dextrin
The present disclosure discloses a method for preparing short-clustered dextrin, and belongs to the field of bio-modified starch. The method includes: collaboratively modifying to-be-modified starch by adopting Ro-GBE and Gt-GBE. The present disclosure utilizes two starch branching enzymes from different microorganism sources to collaboratively modify corn starch. The Ro-GBE is firstly added for pretreatment, then the Gt-GBE is added. The Ro-GBE catalyzes the to-be-modified starch to form a chain segment structure which is more conducive to further utilization for the Gt-GBE, thin and long starch molecule is transformed into short-clustered structure under the catalysis of Gt-GBE, and thus the slow digestibility of modified products is more obvious. Further, by changing the addition amount of Ro-GBE, modification time and the state of to-be-modified starch, the synergistic effect between the two branching enzyme is promoted, and the branching degree is improved, thus the SDS content and the RS content are further improved.
US11214627B2 Anti-IgE antibodies
The present invention relates to the area of improved anti-IgE antibodies and antigen binding agents, and compositions thereof, which target IgE, for instance: for use in treating disorders caused by IgE (such as allergic responses, or certain autoimmune responses); and, in particular, disorders caused by the interaction of IgE with the FcεRI receptor. In particular, this invention relates to improved anti-IgE antibodies and antigen binding agents related to novel mutants of omalizumab (Xolair®). The improved anti-IgE antibodies and antigen binding agents of the invention may have improved affinity for IgE and/or an improved interaction with the Cε2 domain of IgE and/or an improved modified epitope on IgE (for instance further involving the Cε2 domain of IgE) and/or the ability to disassociate IgE from the FcεRI receptor for instance at pharmaceutically-relevant concentrations. In one aspect, improved or novel treatments for IgE mediated disorders are disclosed in which IgE is targeted (for instance free IgE and/or IgE complexed with the FcεRI receptor).
US11214623B2 Antibody capable of neutralizing substance having activity alternative to function of coagulation factor VIII (FVIII)
The present inventors attempted to produce antibodies that neutralize the activity of a substance having an activity of functionally substituting for FVIII to be used for the method of measuring the reactivity of FVIII in the presence of a substance having an activity of functionally substituting for FVIII. As a result, the inventors discovered that by using the produced antibodies, FVIII activity in the plasma of a hemophilia A patient can be evaluated accurately by one-stage clotting assay based on APTT, and also that FVIII inhibitor titer in the plasma of a hemophilia A patient carrying a FVIII inhibitor can be evaluated accurately by Bethesda assay based on APTT.
US11214621B2 Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist
The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
US11214620B2 Binding molecules binding PD-L1 and LAG-3
The present invention relates to antibody molecules which bind to programmed death-ligand 1 (PD-L1) and lymphocyte-activation gene 3 (LAG-3). The antibody molecules preferably comprise a CDR-based antigen binding site for PD-L1, and a LAG-3 antigen binding site which may be located in two or more structural loops of a CH3 domain of the antibody molecule. The antibody molecules of the invention find application, for example, in cancer therapy.
US11214618B2 LAG-3 binding members
The present invention relates to specific binding members which bind to lymphocyte-activation gene 3 (LAG-3). The specific binding members preferably comprise a LAG-3 antigen-binding site which may be located in two or more structural loops of a CH3 domain of the specific binding member. The specific binding members of the invention find application, for example, in cancer therapy.
US11214614B2 LTBP complex-specific inhibitors of TGFβ and uses thereof
Disclosed herein are inhibitors, such as antibodies, and antigen-binding portions thereof, that selectively bind complexes of LTBP1-TGFβ and/or LTBP3-TGFβ. The application also provides methods of use of these inhibitors for, for example, inhibiting TGFβ activation, and treating subjects suffering from TGFβ-related disorders, such as fibrotic conditions. Methods of selecting a context-dependent or context-independent isoform-specific TGFβ inhibitor for a subject in need thereof are also provided.
US11214612B2 Anti-gliadin antibodies, encoding nucleic acids and methods of detecting gliadin
The present invention provides anti-gliadin antibodies and antibody fragments, and polypeptides encoding the antibodies or fragment. Also disclosed are methods and Kits for the use of such antibodies, fragments, or polypeptides in detection of gliadin. Further provided are heavy chain and light chain variable sequences and associated sequences of complementarity-determining regions (CDRs).
US11214611B2 Antibody capable of binding to influenza virus intranuclear protein, complex, detection apparatus and detection method using same
The present disclosure provides an antibody capable of binding to an intranuclear protein of an influenza virus and an application thereof. The present disclosure provides an antibody capable of recognizing a peptide consisting of the 205th-231st amino acid sequence in SEQ ID NO: 24.
US11214608B2 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11214607B2 Glucagon-receptor selective polypeptides and methods of use thereof
This invention relates to isolated polypeptides that are glucagon-receptor selective analogs and peptide derivatives thereof. These analogs are selective for human glucagon receptor with improved solubility, thermal stability, and physicochemical properties as compared to native endogenous glucagon. This invention also relates to methods of using such polypeptides in a variety of therapeutic and diagnostic indications, as well as methods of producing such polypeptides. These analogs are useful, alone or in combination with other therapeutic peptides, in methods of treating obesity, diabetes, metabolic disorders, and other disorders or disease.
US11214606B2 Compositions, formulations and interleukin production and purification
Described herein are cholix-IL-10 fusion proteins, and methods of use thereof, which can be characterized by a distinct response in an individual when administered. This distinct response can comprise changes in levels of one or more markers in the individual and/or co-localization of IL-10 in the Lamina propria of the individual. Further described herein, in some embodiments, are oral formulations of the cholix-IL-10 fusion proteins. Described herein are methods for the purification of an IL-10 delivery construct, including methods for refolding and enrichment, which can result in maintenance of a high percentage of the IL-10 delivery constructs in the biologically active dimer form. Described herein are oral formulations configured for site-specific release of a therapeutic protein in the small intestines or colon. In some cases, the therapeutic protein is in the form of a dimer, such as an IL-10 delivery construct capable of crossing the gut epithelium.
US11214605B2 Light single-chain fusion polypeptides, encoding nucleic acid molecules and host cells
The present invention refers to single-chain fusion proteins comprising three soluble TNF superfamily (TNFSF) cytokine domains and nucleic acid molecules encoding these fusion proteins. The fusion proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
US11214602B2 Coversin variants lacking C5 binding
The invention is directed to modified Coversin polypeptides which exhibit leukotriene or hydroxyeicosanoid binding activity and reduced or absent C5 binding relative to the unmodified Coversin polypeptide; to nucleic acid molecules encoding said modified Coversin polypeptides; vectors and host cells comprising said nucleic acid molecules; and methods of treating or preventing diseases or conditions mediated by a leukotriene or hydroxyeicosanoid in a subject comprising administering said modified polypeptides or nucleic acids to a subject.
US11214599B2 Recombinant simian adenoviral vectors encoding a heterologous fiber protein and uses thereof
The present invention relates to novel adenovirus strains with an improved seroprevalence. In one aspect, the present invention relates to isolated polypeptides of adenoviral capsid proteins such as hexon, penton and fiber protein and fragments thereof and polynucleotides encoding the same. Also provided is a vector comprising the isolated polynucleotide according to the invention and adenoviruses comprising the isolated polynucleotides or polypeptides according to the invention and a pharmaceutical composition comprising said vector, adenovirus, polypeptide and/or polynucleotide. The invention also relates to the use of the isolated polynucleotides, the isolated polypeptides, the vector, the adenoviruses and/or the pharmaceutical composition for the therapy or prophylaxis of a disease.
US11214594B2 Antimicrobial peptide having synergistic antibacterial effect with antibiotics on multidrug resistant bacteria, and use thereof
The present invention relates to an antimicrobial peptide having an improved antibacterial effect through glutamic acid substitution and, more specifically, to a use of the antimicrobial peptide as an active ingredient in an antibacterial pharmaceutical composition, a food additive, a feed additive, an antiseptic composition, and an antibacterial quasi-drug composition. Not only does the antimicrobial peptide of the present invention exhibit significant antibacterial activity against gram-negative bacteria, but it also exhibits a significant synergistic effect when combinedly treated with antibiotics which have strong antibacterial activity only against gram-positive bacteria and has no or low antibacterial activity against gram-negative bacteria, thereby exhibiting excellent antibacterial effects on gram-positive bacteria, E. coli and Acinetobacter bacteria among gram-negative bacteria, and antibiotic-resistant strains thereof.
US11214593B2 Anticancer peptides and uses thereof
The present invention provides a peptide of formula (I), or a pharmaceutically acceptable salt thereof, wherein the N-terminal group of the peptide is a monoradical of formula —NHR1; the C-terminal group of the peptide is a monoradical of formula —C(O)—R2; R1 is a monoradical selected from hydrogen and —C(O)—(C1-C20)alkyl; R2 is a monoradical selected from —OH and —NR3R4 radical; R3 and R4 are independently selected from hydrogen and (C1-C10)alkyl; “a” to “j” are integers from 0 to 1, provided that at least one of “a” to “j” is 1; and X1 represents any amino acid. The present invention also provides conjugates and compositions comprising the peptide of formula (I). The peptide can be used in the treatment or prevention of neoplastic diseases such as pancreatic cancer. CaCbCcCdCeFEX1SKYCfCgChCiCj  (I)
US11214591B2 Enzyme compositions, steroid derivatives, enzyme inhibitors, and methods of making same for pharmaceutical applications
The present disclosure provides for a synthetic strategy to incorporate a C12α-hydroxy group from the methylene (—CH2-) in a steroid backbone, combining synthetic chemistry and enzymology techniques to develop a selective inhibitor for cytochrome P450 8B1, and developing a selective P450 8B1 inhibitor, which can be used as a tool to study P450 8B1 and treat health issues.
US11214588B2 Synthesis of oligosaccharides
This invention relates to a method for the enzymatic synthesis of oligosaccharides, preferably human milk oligosaccharides (HMOs) The method comprises the enzymatic transfer of a glycosyl moiety and subsequent removal of by-products, such as lactose, by nanofiltration using a membrane comprising an active polyamide layer.
US11214587B2 Organic electroluminescent materials and devices
Novel phosphorescent OLED emitters based on metal complexes with indolizine-derived heterocycles as ligands are disclosed. Structural variations of the ligands provide access to a variety of green, yellow and red emitters.
US11214582B2 4-substituted benzoxaborole compounds and uses thereof
Substituted benzoxaboroles whose structure comprises Formula (III), wherein R3 is selected from —CH3, —CII2CII3, —CII2═CII2, —CII2CII2CII3, —CH(CH3)2, —CH2CH2═CH2, and cyclopropyl, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, and —CH(CH3)2; compositions containing such compounds, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
US11214578B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof
Disclosed are compounds of general formulas I-III that may be used to inhibit the action of fatty acid amide hydrolase (FAAH), monoacylglycerol lipase (MAGL) or dual FAAH/MAGL.
US11214577B2 Morphinans useful for treating medical disorders
The present invention related to novel morphinans, compositions comprising the novel morphinans, and their uses as agonists of the kappa opioid receptor.
US11214573B2 Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors
The present invention provides azetidinyl phenyl, pyridyl, or pyrazinyl carboxamide derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase (JAKs) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
US11214567B2 Small molecule inhibitors of MYC and uses thereof
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having an oxadiazole-oxadiazolone structure (e.g., oxadiazole-phenyl-oxadiazolone compounds, oxadiazole-pyridine-oxadiazolone compounds, oxadiazole-indole-oxadiazolone compounds, oxadiazole-quinoline-oxadiazolone compounds, oxadiazole-pyrrole-oxadiazolone compounds, and oxadiazole-vinyl-oxadiazolone compounds), and their use as therapeutics for the treatment of cancer and other diseases.
US11214566B2 Substituted pyridine derivatives useful as C-FMS kinase inhibitors
The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives in the treatment of disorders mediated by c-fms kinase. The present invention is further directed to a process for the preparation of said substituted pyridine derivatives.
US11214565B2 Compound, compositions, and methods
Compounds having activity as LRRK2 inhibitors are disclosed. The compounds are of formula (I) including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds are also disclosed.
US11214562B2 Cyclohexyl benzamide compounds
A compound of the Formula (1) is below provided where R1-R5 are as described in the description and each “*” represents a chiral center.
US11214561B2 Histone methyltransferase EZH2 inhibitor, preparation method and pharmaceutical use thereof
The invention relates to a histone methyltransferase EZH2 inhibitor, a preparation method and pharmaceutical use thereof. In particular, the invention relates to a compound represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the same, and a use thereof as a histone methyltransferase EZH2 inhibitor for treating diseases associated with the histone methyltransferase EZH2, especially cancer. The definition of each substituents in the general formula (I) is same as the definition in the specification.
US11214560B2 Modulators of P97 AAA ATPase activity
The present technology is directed to methods of inhibiting or modulating p97 and compounds and compositions useful in such methods Diseases and conditions that can be treated with the compounds and compositions of the present technology include, but are not limited to, antibacterial infection, antiviral infection, cancer and neurodegenerative disorders susceptible to treatment by inhibition or modulation of p97.
US11214555B2 Method for depleting 2-methoxyethanol (MOE)
A process for the depletion of 2-methoxyethanol (MOE) from a mixture comprising predominantly morpholine (MO) (crude morpholine), wherein crude morpholine is distilled in a distillation column in the presence of an alkali metal compound of the general formula M+[RO−] (M+ is alkali metal cation and R is hydrogen (H), methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl, sec-butyl or tert-butyl), where MO and a compound of the general formula R—OH are distilled off and an alkali metal methoxyethoxide of the general formula M+[MeOEtO−] is obtained in the bottom of the column.
US11214550B2 Bis-cyclic guanidines as antibacterial agents
Provided are novel bis-cyclic guanidine compounds, and the use thereof for treating bacterial infection.
US11214549B2 Process for making higher ethylene amines
Urea derivatives, methods for preparing ethylene amines, and methods of polymer manufacturing are provided. An exemplary method for preparing ethylene amines with n ethylene units and n+1 amine groups wherein n is at least 4, or urea derivatives of said ethylene amines, includes reacting an ethanolamine-functional compound, an amine-functional compound, and a carbon oxide delivering agent, wherein the ethanolamine-functional compound is of the formula HO—(C2H4-NH-)qH, q is at least 1, the amine-functional compound is of the formula H2N—(C2H4-NH-)rH, r is at least 1, the sum q+r is at least 4 and wherein optionally one or more of the ethanol-amine functional compound or amine-functional compound are at least partly used as their cyclic carbamate derivative, or linear or cyclic urea derivative.
US11214546B2 Dithioester compound
An object of the present invention is to provide a dithioester compound capable of generating an alkoxy radical having high hydrogen abstraction ability. The present invention provides a dithioester compound represented by a formula (1). The dithioester compound according to the present invention is capable of generating an alkoxy radical (R1R2R3CO.) having high hydrogen abstraction ability. Thus, the dithioester compound according to the present invention can be suitably used as an additive (RAFT agent) when synthesizing a polymer material having a crosslinked structure. [In the formula (1), R1 to R3 each independently represent an alkyl group having 1 or more carbon atoms, an alkenyl group having two or more carbon atoms, an alkynyl group having two or more carbon atoms, a hydrogen atom, or a halogen atom.]
US11214545B2 Industrial process of mono-alkylating piperidine nitrogen in piperidine derivative with deuterated-lower-alkyl
The present invention relates to a method of mono-alkylating a piperidine nitrogen in a piperidine derivative with a deuterated lower-alkyl, which comprises protecting the piperidine nitrogen with an aralkyl protective group, lower-alkylating the piperidine nitrogen with a deuterated-lower-alkylating agent under neutral or basic condition, and then deprotecting the aralkyl protective group.
US11214544B2 Dextrorphan prodrugs and processes for making and using them
The presently described technology provides compositions of one or more of oxoacids, polyethylene glycols, and/or vitamin compounds chemically conjugated to dextrorphan, (+)-17-methylmorphinan-3-ol), to form novel prodrugs and compositions of dextrorphan.
US11214542B2 Histone demethylase inhibitors
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or amidopyridazine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
US11214541B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof
Compounds of formula (I): wherein R1 and R2 represent hydrogen or deuterium atoms; R3 represents a hydrogen atom or a —COOH, a —OH or a —OPO(OH)2 group; R4 represents a hydrogen atom or a fluorine atom; R5 represents a hydrogen atom or a —OH group; wherein at least one of R3 or R5 is different from a hydrogen atom; when R3 represents a —COOH, —OH or —OPO(OH)2 group, then R5 represents a hydrogen atom; when R5 represents a —OH group, then R3 and R4 represent hydrogen atoms; and R6 is selected from an optionally substituted phenyl, heteroaryl, cycloalkyl and heterocycloalkyl group; and the preparation and the therapeutic uses of the compounds of formula (I) as inhibitors and degraders of estrogen receptors, useful especially in the treatment of cancer.
US11214538B2 Farnesoid X receptor agonists and uses thereof
Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
US11214537B2 Method for making anti-cancer compounds
Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
US11214535B2 Method for producing ethyleneamines
The invention relates to processes for preparing alkanolamines and ethyleneamines in the liquid phase, by reacting ethylene glycol and/or monoethanolamine with ammonia in the presence of an amination catalyst comprising one or more active metals selected from Sn and the elements of groups 8, 9, 10 and 11 of the Periodic Table of the Elements, wherein the amination catalyst is obtained by reductive calcination of a catalyst precursor. The catalyst precursor here is preferably prepared by contacting a conventional or catalytic support material with one or more soluble compounds of the active metals and optionally one or more soluble compounds of added catalyst elements. The present invention further relates to a process for preparing an amination catalyst comprising one or more active metals selected from Sn and the elements of groups 8, 9, 10 and 11 of the Periodic Table of the Elements, the amination catalyst being obtained by reductive calcination of a catalyst precursor, wherein the reactor in which the catalyst precursor is reductively calcined is connected to a denox plant, and to the use of a denox plant in the preparation of amination catalysts.
US11214534B2 Acrylic acid purification via dividing wall columns
The present disclosure relates to a process for producing high-purity acrylic acid using a dividing wall distillation column and in some instances using water as an entrainer and azeotroping agent. This disclosure provides a process for separating acrylic acid from recovered feed streams which comprise saturated organic acids including propionic acid. The resulting acrylic acid product is of sufficient purity to produce acrylate esters and high molecular weight acrylic acid polymers.
US11214533B2 Readily biodegradable alkoxylate mixtures
A mixture of octanols, nonanols and decanols is useful for the preparation of alkoxylates, which alkoxylates may be used as surfactants, which surfactants have surprisingly good biodegradability.
US11214531B2 Alphaolefin oligomer having uniform structure and method of preparing same
The present invention relates to an alphaolefin oligomer having a uniform structure and a method of preparing the same, in which the alphaolefin oligomer has a uniform molecular structure with a low branch ratio, thereby exhibiting improved thermal and oxidative stability, a long service life, low volatility, a low pour point and a high viscosity index.
US11214527B2 Solvent systems for dicyandiamide and/or alkyl thiophosphoric triamide and use in agricultural applications
An inhibitor composition contains dicyandiamide as a nitrification inhibitor, alkyl thiophosphoric triamide as a urease inhibitor, or a combination thereof, dissolved in a liquid medium comprising an organic solvent selected from, among others, one or more polar aprotic solvents, including one or more organophosphates, amine solvents, heterocyclic alcohol solvents, and mixtures thereof, is useful in making fertilizer compositions and in a method of fertilizing target plants.
US11214526B2 Use of calcium sulfate in an inorganic mortar system based on aluminous cement to increase load values
An inorganic mortar system for a chemical fastening of an anchor in a mineral surface includes calcium sulfate, a component A, and a component B for initiating a curing process. Component A includes water, aluminous cement, at least one plasticizer, and at least one blocking agent selected from phosphoric acid, metaphosphoric acid, phosphorous acid, and a phosphonic acid. Component B includes an initiator, at least one retarder, at least one mineral filler, and water. Component A is also a curable composition.
US11214524B2 Honeycomb structure
A honeycomb structure includes a plurality of prismatic columnar shaped honeycomb segments; a bonding layer bonding side faces of the honeycomb segments; and a circumferential wall disposed to surround a honeycomb segment bonded body having the honeycomb segments arranged in a grid pattern and bonded with the bonding layer, wherein the honeycomb segments has a porous partition wall disposed to surround a plurality of cells, the cells in other than outermost circumference have a hexagonal shape in a section orthogonal to the cell extending direction, the honeycomb segments include first and second honeycomb segment, the second honeycomb segment is different from the first in at least one of: a shape in the section; a size; and an arrangement direction of the cells and an extended line of one diagonal line imaginarily depicted in the cells in the first honeycomb segment and that in the second are configured to be orthogonal.
US11214518B2 Fastening system and use thereof
A fastening system for chemically fastening an anchor, the fastening system including a chemical anchor that is a ready-for-use two-component mortar system based on albuminous cement, and an anchor rod comprising an attachment region and an anchoring region. The anchor rod is insertable into a borehole and has a profiled section including a plurality of expansion sections disposed axially in a row which are conically shaped.
US11214515B2 Glass-based articles having stress profiles with high stored energy and methods of manufacture
Glass-based articles having defined stress profiles and methods for manufacturing such glass-based articles are provided. A non-limiting glass-based article comprises an outer region extending from the surface to a depth of compression, wherein the outer region is under a neutral stress or a first compressive stress, a core region under a second compressive stress, the second compressive stress defining a compression peak having a maximum compression value and a maximum width at zero stress in a range of from about 1 micrometer to about 200 micrometers, and an intermediate region disposed between the surface and the core region, wherein the intermediate region is under a tensile stress.
US11214501B2 Combined electrochemical impinging stream reaction apparatus
Disclosure is combined electrochemical impinging stream reaction apparatus with addition of ultrasonic of the invention and is used for illustrating the structure and the mutual position relationship of components of the apparatus. The combined electrochemical impinging stream reaction apparatus with addition of ultrasonic comprises a container frame to hold all the components, an electrocoagulation unit which is attached to the hopper type casing. The hopper type casing contains a conical filter arrangement. The combined electrochemical impinging stream reaction apparatus is configured for the removal of contaminants from water and wastewater.
US11214500B2 Spiral wound assembly with integrated flow restrictor and sensor
A spiral wound assembly including a pressure vessel including an inner chamber, feed inlet, concentrate outlet and permeate outlet and a spiral wound membrane module located within the inner chamber of the pressure vessel; wherein the assembly is characterized by including: i) a flow restrictor comprising: a first and second plate in sealing contact with one another; and a fluid channel located between the first and second plate and including a first end in fluid communication with at least one of the concentrate outlet and the permeate outlet, and a second end adapted for discharging fluid from the spiral wound assembly; and ii) a sensor sheet comprising at least one sensor element located between the first and second plates and in contact with the fluid channel, wherein the sensor sheet is adapted for measuring a property of fluid passing through the fluid channel.
US11214498B2 Refrigeration facility cooling and water desalination
The present disclosure provides systems for refrigeration facility cooling and water desalination. In certain aspects, the systems include a refrigeration facility having a water cooling subsystem configured to receive cool water and output warm water and a desalination plant co-located with the refrigeration facility and configured to receive and desalinate the warm water. Aspects of the invention also include methods for cooling a refrigeration facility using a water cooling subsystem and desalinating water with a desalination plant that is co-located with the refrigeration facility.
US11214496B2 Electrolytic manganese dioxide and method for its production, and its application
To provide electrolytic manganese dioxide excellent in packing property and high-rate discharge characteristics when used as a cathode material for alkaline dry cells. Electrolytic manganese dioxide in which the half-value width of the (110) plane in XRD measurement using CuKα line as the radiation source is at least 1.8° and less than 2.2°, the peak intensity ratio of X-ray diffraction peaks (110)/(021) is at least 0.70 and at most 1.00, and the JIS-pH (JIS K1467) is at least 1.5 and less than 5.0; a method for producing the electrolytic manganese dioxide; and its application.
US11214495B2 Preparation method of phosphotungstic acid
A preparation method of phosphotungstic acid includes mixing a mixed solution containing tungsten, phosphorus and an inorganic acid with an organic-alcohol-containing oil phase for extraction, stripping the obtained supported organic phase and distilled water according to an oil phase:aqueous phase volume ratio of 3:1 to 10:1 to obtain a stripping solution; and carrying out thermal evaporation crystallization or spray drying on the stripping solution to obtain a phosphotungstic acid crystal, wherein the organic alcohol is a C7-C20 alcohol. The inventors have found out that the addition of an inorganic acid to a solution of phosphorus or tungsten and the use of an organic alcohol as an extractant can achieve simultaneous and efficient extraction of phosphotungstic acid. It has also been found that the organic-alcohol-containing oil phase has excellent selectivity for phosphotungstic acid molecules in the mixed solution.
US11214494B2 Spinel compound oxide particle, method for producing the same, resin composition including spinel compound oxide particle, and molded article
A spinel compound oxide particle includes metallic atoms, aluminum atoms, oxygen atoms, and molybdenum atoms, wherein the metallic atoms are selected from the group consisting of zinc atoms, cobalt atoms, and strontium atoms, and a crystallite size in a [111] plane is 100 nm or more. Included are a step (1) of firing a first mixture including a molybdenum compound and a metallic-atom-containing compound or a first mixture including a molybdenum compound, a metallic-atom-containing compound, and an aluminum compound to prepare an intermediate; and a step (2) of firing, at a temperature higher than a temperature selected in the step (1), a second mixture including the intermediate or a second mixture including the intermediate and an aluminum compound.
US11214492B2 Silica particles
The object of the present invention is to provide silica particles which can provide a silica particle dispersion exhibiting excellent uniformity. The present invention is silica particles having an average primary particle diameter dBET calculated from a specific surface area by a BET method of 1 nm or more and 100 nm or less and a ratio (dDLS/dBET) of an average secondary particle diameter dDLS measured by a dynamic light scattering method to the dBET of 1.2 or less. The silica particles of the present invention preferably have a coefficient of variation in a particle diameter measured using a transmission electron microscope at a magnification of 200,000 of 20% or less.
US11214484B2 Planar quantum structures utilizing quantum particle tunneling through local depleted well
Novel and useful quantum structures having a continuous well with control gates that control a local depletion region to form quantum dots. Local depleted well tunneling is used to control quantum operations to implement quantum computing circuits. Qubits are realized by modulating gate potential to control tunneling through local depleted region between two or more sections of the well. Complex structures with a higher number of qdots per continuous well and a larger number of wells are fabricated. Both planar and 3D FinFET semiconductor processes are used to build well to gate and well to well tunneling quantum structures. Combining a number of elementary quantum structure, a quantum computing machine is realized. An interface device provides an interface between classic circuitry and quantum circuitry by permitting tunneling of a single quantum particle from the classic side to the quantum side of the device. Detection interface devices detect the presence or absence of a particle destructively or nondestructively.
US11214481B2 MEMS element
According to one embodiment, a MEMS element includes a base body, a supporter, a film part, a first electrode, a second electrode, and an insulating member. The supporter is fixed to the base body. The film part is separated from the base body in a first direction and supported by the supporter. The first electrode is fixed to the base body and provided between the base body and the film part. The second electrode is fixed to the film part and provided between the first electrode and the film part. The insulating member includes a first insulating region and a second insulating region. The first insulating region is provided between the first electrode and the second electrode. A first gap is provided between the first insulating region and the second electrode. The second insulating region does not overlap the first electrode in the first direction.
US11214479B2 Probe assembly for use in a closed transfer system
Embodiments of the invention provide a probe assembly configured to selectively restrict fluid flow through an outlet of a closed transfer system. The probe assembly has an elongate probe body with a top end portion, a bottom end portion, an outer wall, and an internal structure defining a fluid chamber extending from the bottom end portion to the top end portion. The fluid chamber has a fluid chamber inlet at the bottom end portion extending through the outer wall into the fluid chamber and a fluid chamber outlet at the top end portion extending from the fluid chamber through the outer wall. A probe tip with a cylindrical bore is configured to engage the top end portion of the elongate probe body and a probe tip outlet is configured to be in fluid communication with the fluid chamber outlet. A rotating head located circumjacent to the probe tip and adjacent to the probe tip outlet is configured to rotate about the probe tip. The rotating head having an inner surface, an outer surface, and a vane extending from the inner surface through the outer surface.
US11214478B2 Fluid interface to receive removable container
A fluidic interconnect includes a first interface including a liquid port, a gas port, and a cradle; a second interface including a liquid port, a gas port, and a swing bar to engage the cradle, a weight of a container attached to one of the first or second interfaces to drive the liquid port of the first interface into connection with the liquid port of the second interface and the gas port of the first interface into connection with the gas port of the second interface.
US11214477B2 Cock for carbonated water
A cock (10) that receives and discharges the carbonated water from a nozzle (70) includes: a first flow path (4S); and a second flow path (46). A flow path transverse Closs-section has an annular shape. The second flow path has an outer diameter larger than that of the first flow path and having a flow path cross-sectional area smaller than that of the first flow path; and a shaft (50) which forms the inner circumferential surface of the second flow path. the shaft having a ring-shaped groove (52) formed over the outer circumference of the shaft in a part of the second flow path that is connected to the first flow path, wherein a longitudinal center axis line (C1) of the first flow path is nonparallel to and does not intersect with a longitudinal center axis line (C2) of the second flow path.
US11214476B2 System and method for generating a drive signal
A method and computer program product for defining a PWM drive signal having a defined voltage potential. The PWM drive signal has a plurality of “on” portions and a plurality of “off” portions that define a first duty cycle for regulating, at least in part, a flow rate of a pump assembly. At least a portion of the “on” portions of the PWM drive signal are pulse width modulated to define a second duty cycle for the at least a portion of the “on” portions of the PWM drive signal. The second duty cycle regulates, at least in part, the percentage of the defined voltage potential applied to the pump assembly.
US11214474B2 Domestic beverage dispensing device having cooling means and method of using same
A domestic beverage dispensing device includes a conduit for supplying the beverage from keg to a tap and a cooling member. The cooling member has a passage surrounded by heat conductive material. A disposable tube of deformable material forms at least a part of the conduit and extends through the passage. The deformability of the material of the disposable tube is such that the outer surface of the wall of the tube abuts against the inner surface of the passage when the beverage is pressurized.
US11214472B2 Beverage dispensing system
A beverage dispensing system is provided. The beverage dispensing system can include a nozzle module connected to a beverage dispenser housing. The nozzle module can be vertically and/or horizontally spaced from a beverage dispenser valve and nozzle.
US11214471B2 Pallet truck with brake release and lower brake zone detection mechanism
A pallet truck has a brake release mechanism. The pallet truck has a break release mechanism operably coupled to a brake for stopping rotation of a drive wheel. The brake release mechanism includes a brake release sensor and a profile feature that is detectable by the brake release sensor. The profile feature is fixedly coupled to a pivot shaft of a tiller arm of a tiller, and configured to rotate with the pivot shaft as the tiller arm is pivoted. The brake release sensor is positioned adjacent to the pivot shaft and configured to output a signal that causes the brake to release when the profile feature is detected.
US11214470B2 Rope maintenance system
A method of spooling a crane rope (2) onto a crane drum through a crane rope spooling system (1) from a reel (31) under a predetermined back tension is described and includes the steps of: unspooling the crane rope (2) from a reel (31) and passing the crane rope through a tensioning system (10) comprising a primary back tensioner (12) and a secondary back tensioner (16); gripping the crane rope (2) within the secondary back tensioner (16) and thereby preloading the crane rope (2) with tension prior to the crane rope (2) passing through the primary back tensioner (12); and applying a predetermined back tension to the crane rope (2) with the primary back tensioner (12) as the crane rope (2) is being spooled onto the crane drum under the predetermined back tension. A crane rope spooling system (1) for spooling crane rope (2) onto a crane drum under a predetermined back tension is also described, said system (10) comprising a tensioning system (10) comprising at least a primary back tensioner (12) and a secondary back tensioner (16) and a reel (31).
US11214469B2 Lifting devices
The present inventions provides a lifting device 101 comprising a main body 105 being of a generally elongate form, said main body 105 having at one end thereof a transport means 102, 120 to allow said device to translate relative to the ground, a boom portion 103 cooperating with said main body 105 and adapted to support a load at its end, a motive power means 115 to lift or lower said load, said main body 105 being able to be pivoted by a user with respect to a fulcrum 102, 120 formed by either said transport means 102, 120 and a ground location or said transport means 102, 120, around an axis generally parallel to the ground, to transfer or arcuately move a load carried by said boom portion 103, thereby providing a functionally variable horizontal reach 1013 to said device 101.
US11214466B2 Monitoring systems for passenger conveyors
A monitoring system for a passenger conveyor including: at least one acceleration sensor provided on a movable component of the passenger conveyor, wherein the moveable component moves in a closed loop path (P) when the passenger conveyor is in use; a fault detection sensor associated with the or each acceleration sensor and configured to provide data indicative of a fault in the moveable component. The monitoring system includes a controller configured to: receive data from the or each acceleration sensor; monitor a gravity vector (V) of the or each acceleration sensor; determine a direction of travel of the or each acceleration sensor; determine a current location of the or each acceleration sensor based on the monitored gravity vector (V) and the determined direction of travel; detect a fault from the data received from the or each fault detection sensor; identify a location of the detected fault.
US11214465B2 Elevator system suspension member
A belt for suspending and/or driving an elevator system component include one or more metallic cord tension elements extending along a length of the belt, and one or more non-metallic tension elements extending along a length of the belt. Each non-metallic tension element is formed from a non-metallic material. The one or more metallic cord tension elements and the one or more non-metallic tension elements are arrayed laterally across a lateral width of the belt. The belt may be used in an elevator system including a hoistway, a drive machine having a traction sheave coupled thereto, an elevator car movable within the hoistway. The belt is operably connected to the elevator car and interactive with the traction sheave to suspend and/or drive the elevator car along the hoistway.
US11214464B2 Elevator seismic performance apparatus
An elevator car of an elevator system includes a car body, and a car frame supportive of the car body. The car frame includes two or more opposing upright assemblies, a crosshead assembly located above the car body, and a plank assembly located below the car body. A plurality of seismic retainers are located at each of the upright assemblies. The plurality of seismic retainers are configured for a non-contact relationship with a guide rail of the elevator system during normal operation of the elevator system, and configured to react guide rail loads during a sway event via contact with the guide rail.
US11214463B2 Peak traffic detection according to passenger traffic intensity
A method and a control device for controlling an at least one elevator are described, by which an arriving traffic intensity is detected, the traffic intensity being a number of passengers arriving at the at least one elevator during a traffic intensity determination period, a traffic amount value is determined by comparing the traffic intensity to a maximum building population, wherein the maximum building population is a maximum number of people in a building, and the at least one elevator is controlled based on the determined traffic amount value.
US11214459B1 Tape wrap dispenser
A tape wrap dispenser comprising an outer enclosure having a first side with a first aperture, a center section with a tape exit slot, and a second side with a second aperture. Also included are a first release/cut button which is attached to the first side, a second release/cut button which is attached to the second side, and a neck lanyard having a safety quick release routed through both the first aperture and the second aperture. There is a central hub inside the outer enclosure and a tape wrap roll mounted on the central hub and which extends through the tape exit slot. A mechanical linkage connected to the first and second release/cut buttons moves a cutter that cuts the tape at the tape exit slot. The outer enclosure should have a flat surface to prevent rolling.
US11214457B2 Media puller barrier devices
In one example, a media puller device can include a snowplow device coupled to a first end of a hinge, a leading end of the media puller device coupled to a second end of the hinge, and a tension device coupled between the snowplow device and the media puller device.
US11214456B2 Method and arrangement for detecting a filling level in a tissue dispenser
A method and an arrangement for detecting a filling level in a tissue dispenser for dispensing portions of a continuous web of tissue from a tissue roll is adapted for use with. a tissue dispenser for dispensing portions of the continuous web of tissue from the tissue roll. The method comprises the steps of counting portions of the tissue dispensed by the tissue dispenser, determining an initial filling level depending on the counter data and an initial tissue type information, and determining a verified filling level depending on the counter data when a roll exchange of a tissue roll from a first tissue roll position to a second tissue roll position in the tissue dispenser has occurred.
US11214454B2 Medium feeding device and image reading apparatus
A medium feeding device includes a medium feeding mechanism switching between a first state in which the medium is fed from the feeding tray and a second state in which the medium is not fed from the feeding tray, a feeding roller rotationally driven in a forward rotation direction, and a separation roller that is rotationally driven in the reverse rotation direction when the feeding roller is rotationally driven in the forward rotation direction, wherein when the separation roller is rotationally driven in the forward rotation direction, the feeding roller is configured to be passively rotatable with respect to the separation roller, and wherein a rotation direction of the first motor when the cam member switches the medium feeding mechanism from the first state to the second state is the same as a rotation direction of the first motor when the separation roller rotates in the forward rotation direction.
US11214449B2 Glass processing apparatus and methods
A glass processing apparatus to convey a glass sheet along a conveyance path can include a plurality of air bars spaced apart from each other along a first direction extending perpendicular to a central axis. Each air bar can include a surface with a plurality of fluid outlet ports. The glass processing apparatus can include a plurality of plates, and at least one of the plurality of plates can be positioned between ones of the plurality of air bars. Each plate can include a surface with a plurality of fluid inlet ports. The plurality of air bars and the plurality of plates can be symmetrically arranged relative to the central axis. Methods of processing a glass sheet can include emitting fluid from the plurality of fluid outlet ports of each of the plurality of air bars, thereby providing a cushion of fluid.
US11214434B2 Container for flowers and method of operation thereof
Disclosed is a container suitable for holding objects such as flowers and which may include a body having at least one wall defining a cavity. The at least one wall may include openings separated apart from each other. A tensioner may pass through the openings. A platform may be situated within the cavity and coupled to the tensioner so as to receive a force from the tensioner when a tension is applied to the tensioner. This force may be operative to lift the platform and the flower coupled thereto so that the flower partially or fully extends from the cavity while at least a portion of the platform remains in the cavity.
US11214432B2 Solid matter valve for pressurized cans
The invention relates to a solid matter valve for pressurized cans, in particular for the dispensing/discharging of assembly foams, with a valve disk (1), a valve body (2) arranged in the valve disk (1), a stem (3) mounted in a central cuts out (21) of the valve body (2) and having at least one inlet opening (33) for the contents of the pressurized can, said opening being cleared by actuation of the stem (3), with at least one discharge opening, a duct (34) connecting the inlet opening (33) with the discharge opening, at least one sealing element (23) acting between the valve body (2) and the stem (3), as well as a spring element (40), wherein the stem (3) is designed so as to form two parts, the upper part (3a) being connected to the lower part (3b) in a form-closed or force-closed manner, a circumferential elastic diaphragm (22) integrally connecting the valve body (2) to the upper part (3a) of the stem (3), and the two parts (3a, 3b) of the stem (3) forming a functional unit which accommodates the duct (34).
US11214427B2 Repulpable container
A repulpable insulated container assembly having a container formed of paper such as corrugated cardboard or varying paper materials and defining an interior; and a repulpable insert placed within the interior of the container and formed of a first paper layer; and a paper fiber pad coupled to the first paper layer.
US11214426B2 Packaging system for oxygen-sensitive drugs
Described herein are pharmaceutical packaging systems which prevent oxidative degradation of oxygen-sensitive drugs, such systems including a primary packaging container with an oxygen permeable component, a secondary packaging with very low permeability to oxygen and an oxygen absorber.
US11214420B2 Twist-tie dispensing assembly
A twist-tie dispensing assembly for dispensing of loose twist-ties in bulk form comprises a base defining a rear wall and an open front, wherein a flexible portion of the rear wall is configured to elastically deflect through a cut-out provided on the rear wall in a direction from the rear wall toward the open front. A box is mounted to the base, the box defining a back wall and a storage compartment configured to hold twist-ties, the back wall of the base defining a slot exposing the storage compartment to an exterior of the box, wherein the slot is configured to receive at least partially the flexible portion of the rear wall of the base from the exterior of the box toward the storage compartment when the box is mounted to the base.
US11214417B2 Valve assembly for a beverage container
A valve assembly for a beverages container with two components, of which one external container and one internal container, closed at the upper part by a closing device, comprises a valve body made in a single body and a spring device, wherein a mobile sealing unit is present between the valve body and the spring device, configured to selectively open and close a passage aperture of the valve assembly.
US11214415B2 Liquid pouring member and container
A liquid pouring member capable of effectively preventing the liquid from spouting upon opening. An inner plug includes a nozzle, a base to be engaged with an opening of a container, and a hollow cylindrical skirt. The nozzle includes a nozzle upper part extending from an upper surface of the base and a nozzle lower part extending from a lower surface of the base. The nozzle upper part includes an outlet port, and the nozzle lower part includes an inlet port. An inner passage is formed from the inlet port to the outlet port while penetrating therethrough. The nozzle lower part is formed in a radial inner side of the hollow cylindrical skirt, and includes an end portion with an inclined surface. The inlet port is formed in the inclined surface.
US11214413B2 Tethered flip closure
A closure includes a hinged sealing element including a top wall and a first skirt. The first skirt has a sealing formation allowing engagement of a mating sealing formation of a bottle. A second skirt has an attachment formation engageable with a mating attachment formation of the bottle. A plurality of frangible members is attached to each of the skirts. A pair of hinge members is attached between the first and second skirts. A biasing member is attached to the first skirt between the hinge members and extending downwardly from the first skirt to interact with a neck portion of the bottle such that the sealing formation of the first skirt and the mating sealing formation of the bottle are biased toward each other.
US11214407B2 Ventilatable valve bag
The invention relates to a ventilatable valve bag with a wall material (4) comprising at least one gas-permeable inner layer (6) that is impermeable to a filler material and at least one gas-impermeable outer layer (8) as well as two closing sides (10), a first closing side (10) being formed by closing the valve bag (2) and a second closing side (10) being arranged opposite the first closing side (10). An intermediate space (14) is formed between a part of the inner layer (6) defining an inner space (12) of the bag and the outer layer (8), and at least one ventilation channel (18) leading out of a wall material edge section (16) is arranged on at least one closing side (10) of the valve bag (2), between the inner layer (6) and the outer layer (8) of a wall material region, such that the intermediate space (14) can be ventilated to the surroundings.
US11214404B2 Measuring device assembly
A measuring device assembly having a container and measuring receptacle. The container includes a self-supporting base structure with a plurality of projections extending downward therefrom, wherein each projection of the plurality of projections includes a fastener receiving groove extending inward thereof. The measuring receptacle includes a receptacle base, a side wall extending from an upper surface of the receptacle base, and a fastener extending inward and secured in the fastener receiving groove.
US11214403B2 Pallet and logistic system
A pallet has a deck, a skid and a plurality of blocks, spacing the skid from the deck. The blocks comprise spacer portions and sleeve portions, wherein the sleeve portions may extend above and below the spacer portions. The pallet constructed in this way can advantageously be made in any conventional size to meet the relevant norm or standard, while benefitting from the fact that the sleeve portions protect the edges of the deck and/or skid from impact. Furthermore, any impact imparted on the blocks is transmitted by the respective sleeve to the deck and/or skid. A logistic system is also described.
US11214400B2 Package and a slide for such a package
A package comprises a housing and a slide. The slide is slidably accommodated in the housing in a sliding direction. The slide comprises a bottom wall, side walls connected to the bottom wall as well as at least one flange-shaped upper edge spaced from the bottom wall, which is connected to the side walls. The flange-shaped upper edge comprises two parts that extend parallel to the sliding direction. Each part is provided with at least one hook-shaped element. The housing comprises two side walls. Each side wall is provided with at least one recess in which one of the hook-shaped elements connected to the slide can be positioned for at least locking the slide in position in the housing The hook-shaped elements can be moved out of the recesses against spring force, after which the slide can be moved in the sliding direction in the housing. The slide is provided with a box being connected to the bottom wall of the slide. The box comprises walls located at a distance from the side walls of the slide. The walls of the box bound an opening being sealable by means of a foil.
US11214394B2 Apparatus and process for packaging a product
A process for packaging a product (P) arranged in a support (4) comprising unrolling a film (10a), transversely cutting the unrolled portion of film (10a) and preparing cut film sheets (18), moving the cut film sheets (18) to a packaging assembly (8) defining at its inside a packaging chamber (24), progressively moving a number of supports (4) inside the packaging chamber (24) of a packaging assembly (8), keeping the packaging chamber (24) open for a time sufficient for a number of supports (4) and for a corresponding number of film sheets (18) to properly position inside said packaging chamber (24), hermetically closing the packaging chamber (24) with the film sheets held above the respective support (4) and at a distance sufficient to allow gas circulation inside the support (4), optionally causing one or both of: a gas withdrawal from the hermetically closed packaging chamber (24) and gas injection of a gas mixture of controlled composition, heat sealing the film sheet (18) to said support (4), wherein the cutting of the film (10a) into film sheets (18) takes place outside the packaging chamber (24) at a station remote from the location where the film sheets are coupled to the supports. An apparatus (1) for performing the above process is also disclosed.
US11214387B2 Assembly method for an air intake of a jet engine of an aircraft
An assembly method for an air intake of a jet engine of an aircraft, comprising providing an acoustic panel, an outside panel, flanges and a collar, arranging a rear edge of the acoustic panel on an assembly chassis. The flanges and the collar are attached at the rear edge of the acoustic panel. A rear edge of the outside panel is attached to the attached collar. A first set of geometric data of a front edge of the acoustic panel is measured and a second set of geometric data of a front edge of the outside panel is measured. A U-shaped lip as a single element is produced based on the two sets of geometric data. An inside leg of the lip is attached to the front edge of the acoustic panel and an outside leg of the lip is attached to the front edge of the outside panel.
US11214375B2 Spring sealed pneumatic servo valve
A servo valve for an actuator is described. The servo valve comprises a housing having a plurality of ports, a sleeve disposed within the housing, the sleeve comprising an axis (A), an inner surface defining a cavity for the servo valve and a plurality of metering holes, each in communication with one of the ports, and a metering rod extending axially in the cavity for reciprocation along the axis to meter flow through the metering holes. The servo valve additionally comprises a first spring seal extending between the metering rod and the sleeve to close off a first end of the cavity and a second spring seal extending between the metering rod and the sleeve to close off a second, opposite end of the cavity.
US11214366B2 Wind measurement by means of a multicopter
A multicopter including motors driving propellers, a first interface providing parameters including: a position of a center of gravity of the multicopter, time derivatives, an orientation of the multicopter and its time derivative; a second interface providing power generated by respective propellers; a first unit, based on the parameters, a provided model that describes dynamics of the multicopter, and an estimation of a force wrench acting externally on the multicopter, the estimation based on based on the model, determines horizontal components of a relative speed of the multicopter in relation to air; a second unit which, based on the horizontal components and power, determines a vertical component of the relative speed; a third unit which, based on the horizontal components, vertical component, and parameters, determines a wind speed in an inertial system; and a storage unit to store wind speeds and/or a transmission unit to wirelessly transmit the wind speeds.
US11214364B2 Main rotor blade and helicopter
A main rotor blade 1, which is the main rotor blade 1 for a high-velocity helicopter, includes: a blade root part 10 having a length of 30% or more of a rotor radius R; and a blade main body 20 continuous with the blade root part 10. Preferably, a cross-sectional shape of the blade root part 10 satisfies (x/a)m+(y/b)m=1 and a>b, where m: arbitrary number, x: chord length direction, and y: blade thickness direction.
US11214362B2 Vibration isolation systems for advancing blade concept rotorcraft
An advancing blade concept rotorcraft includes an airframe and a pylon assembly subject to vibration. The pylon assembly includes a dual rotor system having coaxially disposed top and bottom rotor assemblies that counter rotate relative to one another. The advancing blade concept rotorcraft includes a vibration isolation system including at least one pylon link coupled to the airframe and the pylon assembly. The pylon link includes a Liquid Inertia Vibration Eliminator unit operable to reduce transmission of the pylon assembly vibration to the airframe. The advancing blade concept rotorcraft includes active force generators adjacent to the pylon assembly. The active force generators include a first active force generator producing a force in a first direction and a second active force generator producing a force in a second direction to counteract multidirectional oscillations of the pylon assembly, thereby reducing vibration of the advancing blade concept rotorcraft.
US11214359B2 Flow control system, flow control method, and aircraft
A flow control system includes a movable wing attachable to a wing of an aircraft, and a plasma actuator mountable on a surface of the movable wing. The flow control system is configured to control air flow around the wing by having the changing of the steering angle of the movable wing work in conjunction with the operation of the plasma actuator.
US11214356B2 Fiber sheet stacked rotor design
A rotor unit is disclosed. The rotor unit includes a hub and a stacked rotor blade. The hub is configured to rotate about an axis in a first rotation direction. The stacked rotor blade is rotatable about the axis and further includes a first blade element and a second blade element. The first blade element has a first leading edge and the second blade element has a second leading edge. The blade elements are arranged in a stacked configuration. A leading edge of the stacked rotor blade is formed by at least a portion of the first leading edge of the first blade element as well as at least as portion of the second leading edge of the second blade element. In some embodiments, the rotor unit is coupled to an unmanned aerial vehicle.
US11214354B2 Control surface actuation mechanism
A control surface actuation mechanism for moving a control surface relative to a fixed aerofoil portion of an aircraft is disclosed including an articulating support, a sliding member on the articulating support and coupled to the control surface, the sliding member arranged to slide relative to the articulating support, a track with a path for attachment on the fixed aerofoil portion, and a rigid connecting element connected to the first track and to the sliding member. The first end of the first rigid connecting element is configured to move passively along the path, as the sliding member is driven to slide relative to the articulating support by an actuator.
US11214352B2 Control surface for an aircraft, and aircraft having a flexible control surface
A control surface of an aircraft comprises a fixed skin panel, a first flexurally elastic skin panel and a second flexurally elastic skin panel, which is connected to the first flexurally elastic skin panel and is configured to at least partially overlap the fixed skin panel. Furthermore, the control surface comprises an actuator system, which is configured to move the second flexurally elastic skin panel parallel to the fixed skin panel, wherein the actuator system has a fixed structural element arranged in a root region of the control surface, and a structural element that is movable relative to the fixed structural element.
US11214350B2 Sound attenuation panel and methods of constructing and installing the same
A sound attenuation panel that includes an incident wall and a frame unit connected to the incident wall. The incident wall defines an aperture therethrough. The frame unit includes multiple spoke members spaced apart from one another and radially extending from one or more central hub openings of the frame unit. The one or more central hub openings align with the aperture of the incident wall. The frame unit defines channels between adjacent pairs of the spoke members. The channels fluidly connect to the one or more central hub openings. The frame unit is configured to receive sound waves into the central hub opening through the aperture of the incident wall to dissipate the sound waves through the channels between the spoke members.
US11214349B2 Stringers for aircraft skin structures and related methods
Stringers and aircraft skin structures and related methods are disclosed. An example apparatus includes a skin structure and a support. The support includes a first surface, a second surface opposite the first surface, and a tapered edge extending from the first surface. The example apparatus includes a first material disposed between a first portion of the support and a first portion of the skin structure to couple the second surface of the support to the skin structure and a second material disposed between a second portion of the support and a second portion of the skin structure. The second material is different than the first material. The second portion of the support includes at least a portion of the tapered edge.
US11214343B2 Autonomous underwater vehicle
An autonomous underwater vehicle (AUV) for sensing at a seabed is provided. The AUV is configured to be grounded in a stationary condition on the seabed. The AUV comprises a body (100), a sensing module configured to acquire data when the vehicle is grounded on the seabed, and a multiplane wing configuration (200) extending from the body. The multiplane wing may be a box wing.
US11214336B2 Rotational leash plug system for surf boards
The invention discloses a rotational leash plug system for surf boards including an outer ring housing, a spherical or cylindrical element, in particular a ball or a cylinder, a stainless steel or brass pin attached to the rolling element and a bottom cap. A safety surf leash is attached to the pin centered in the ball to achieve a safety connection between surfer, in particular attached to the leg of the surfer, and a surfboard. The rotational element is free to rotate in x, y, and z axis inside the outer ring housing and the bottom cap. The spherical element is able to follow the force vector of the leash pulling the pin. The surf plug system can therefore follow the movement of the safety surf leash and or the surfer attached to the leash as soon as there is a pull force applied to the pin inside the surf plug system.
US11214335B2 Wake-modifying device for a boat
A recreational sport boat includes a hull having starboard and port sides and a transom, a generally horizontal platform, and a pair of wake-modifying devices positioned aft of the transom. The generally horizontal platform extends aft of the transom and is configured to support a human weighing at least 100 lbs. on an upper surface thereof. The pair of wake-modifying devices are attached to the platform. One of the wake-modifying devices is positioned on a port side of the platform's centerline, and another of the wake-modifying devices is positioned on a starboard side of the platform's centerline. Each wake-modifying device is moveable between a non-deployed position and a deployed position in which the wake-modifying device is angled downwardly at an angle relative to the top surface of the generally horizontal platform.
US11214326B2 Footrest with integrated tow handle for portable conveyance
A portable conveyance footrest has a support portion having a substantially planar base surface to receive a foot. A tow handle portion is connected to an end of the support portion and forms a substantially planar tow handle that is within a same plane as the substantially planar base surface. The tow handle is spaced apart from the end of the support portion to define a void between the tow handle and the second end of the support portion. The tow handle is disposed within the same plane as the substantially planar base surface so that a user's fingers, when gripping the tow handle, extend into the void between the tow handle and the end of the support portion and through the plane of the substantially planar surface.
US11214321B1 Vertical non-linear automotive assembly
A manufacturing system for assembling a vehicle includes a structure having a plurality of levels and including a plurality of manufacturing cells distributed among the plurality of levels. The manufacturing system includes a plurality of manufacturing capsules disposable at the plurality of manufacturing cells and configured to support a vehicular manufacturing process to assemble the vehicle, where the vehicular manufacturing process includes a plurality of manufacturing operations. The manufacturing system includes a transport system configured to move the plurality of manufacturing capsules to the plurality of manufacturing cells, where the transport system includes a vertical transport system configured to longitudinally move the plurality of manufacturing capsules between the plurality of levels. The manufacturing system includes a control system configured to control movement of the manufacturing capsules with the transport system.
US11214318B1 Automotive vehicle with folding tailgate
An illustrative folding tailgate for an automotive vehicle includes a first wall portion and a second wall portion that are rotatably connected to one another. A first latch may be attached to the first wall portion and configured to engage with a complementary latch part at a first portion of a vehicle to lock the tailgate in a closed position. A guide member may be attached to the first wall portion and configured to move along a rail disposed at a rear of the automotive vehicle, the guide member configured to move along the rail in a manner constrained by the rail. A rotatable connection mechanism may be attached to the second wall portion and configured to attach to a second portion of a vehicle. The tailgate may be configured to open and close via folding movement of the first and second wall portions relative to one another.
US11214315B2 Underbody structure of vehicle
A floor center member extends through a central part of a body floor of a vehicle and a longitudinal direction of the vehicle, and a first floor cross member penetrates the floor center member to extend in a lateral direction of the vehicle. The floor center member includes a coupling flange counter to a top wall of the first floor cross member. The coupling flange is coupled to the first floor cross member, by a bolt and a nut.
US11214310B2 Vehicle body on which a high voltage battery is mounted
A vehicle body on which a high voltage battery is mounted is provided. The vehicle body includes a vehicle body floor on which a battery is placed stably, side sills disposed on both lateral sides of the vehicle body floor, respectively, to extend in forward and backward directions, a plurality of coupling members, wherein front portions of the coupling members are combined with respective front side members, rear portions of the coupling members are combined with the side sills, respectively, and each coupling member connects, in an extension line, between the respective front side member and the respective side sill in the forward and backward directions, and a cross member that extends across the vehicle body floor and couples the coupling members, wherein each end of the cross member is combined with the respective side sill.
US11214305B2 Steering system for a vehicle
A vehicle steering system has a pitman arm being pivotable about a pitman arm pivot axis in response to pivoting of a steering column, a link pivotally connected to the pitman arm, an idler arm pivotally connected to the link and being pivotable about an idler arm pivot axis, the link extending between the pitman arm and the idler arm, a first tie rod pivotally connected to the pitman arm and extending from the pitman arm in a first direction, and a second tie rod pivotally connected to the idler arm and extending from the idler arm in a second direction, the second direction being opposite the first direction. A vehicle having the vehicle steering system is also described.
US11214302B2 Method for the control of vehicle steering
Methods of controlling a feedback torque actuator in a steering system that includes the feedback torque actuator and an assistance actuator incorporate, for feedback torque control, generating at least one input signal with a sensor, determining a steering angle from the input signal, transforming the steering angle to a target steering-wheel torque, and controlling the feedback torque actuator via a closed loop current control to achieve the target steering-wheel torque. The assistance actuator has a high gain, thereby resulting in a low torque in the axle above the assistance actuator such that the steering-wheel torque is close to the target steering-wheel torque, whereby acceptable steering feel is achieved.
US11214294B2 Retractable steering wheel
A steering wheel assembly has a central hub configured to connect to a steering column, at least one retractable hand grip attached to the central hub, one or more control cables disposed internal of each retractable hand grip, and a drive mechanism connected to the control cables. The drive mechanism is located either at or in the central hub or remotely relative to the steering wheel assembly. The drive mechanism when activated can selectively move one or more of the control cables to move the retractable grips to a retracted position or a non-retracted position. Optionally, the hand grips can be connected directly to the central hub and/or to one or more spokes extending form the central hub. Each of the retractable hand grips has at least one and up to four control cables.
US11214291B2 Wagon with adapter for installing child seat
A seat adapter removably mounts a child seat to a wagon having two opposing walls and an interposed connecting wall, and includes two latch components that mount to the wagon's opposing walls. In some embodiments, the seat adapter includes a cross-member extending between the latch components so that the cross-member provides structural integrity to the wagon if the connecting wall is displaced from its upright use position. In some embodiments, the seat adapter and the child seat can be mounted to the wagon for use with the connecting wall in its upright use position, and in some embodiments the seat adapter and the child seat can be mounted to the wagon for use whether the connecting wall is in its upright use position or its displaced position, with no mechanical interference between any part of the wagon and any part of the adapter or the child seat mounted to it.
US11214289B2 Multi-functional folding trolley
A multi-functional folding trolley comprises a trolley frame including a front wall, two side walls, and a rear wall, wherein the front wall and the rear wall are formed by frames composed of connection rods, and the two side walls are formed by scissor-shaped connection rod assemblies. The multi-functional folding trolley further comprises an angle-adjustable trolley pushing mechanism connected to a rear upper part of the frame of the rear wall and an axle mechanism located at a rear lower part of the frame of the rear wall and having two sides respectively provided with tires capable of being assembled and disassembled rapidly. The two-wheeled multi-functional folding trolley of the invention is suitable for various occasions.
US11214288B2 Method and apparatus for a train control system
A method and an apparatus for a train control system are disclosed, and are based on virtualization of train control logic and the use of cloud computing resources. A train control system is configured into two main parts. The first part includes physical elements of the train control system, and the second part includes a virtual train control system that provides the computing resources for the required train control application platforms. The disclosed architecture can be used with various train control technologies, including communications based train control, cab-signaling and fixed block, wayside signal technology. Further, the disclosure describes methodologies to convert cab-signaling and manual operations into distance to go operation.
US11214283B2 Tank system and vehicle
A tank system includes an extraction device and a tank. The extraction device has an extraction line and an attachment device. The tank includes a tank top side having a fastening wall and a first tank top side section. The fastening wall and the first tank top side section delimit a tank interior space at the top side. The tank interior space can be filled with an exhaust-gas after-treatment liquid, the fastening wall is disposed obliquely to the first tank top side section, the fastening wall has a fastening surface and a tank opening, the attachment device is fastened to the fastening surface, and the extraction line is guided through the tank opening. A vehicle having the tank system is also provided.
US11214280B2 Autonomous vehicle providing driver education
A method is disclosed for using an autonomous vehicle to teach a student how to drive. The method may include generating, by the autonomous vehicle during a training session, a plan for navigating a section of road. During the training session, the autonomous vehicle may receive control instructions from the student regarding how the student would like to navigate the section of road. If the autonomous vehicle determines that implementing the instructions would be safe and legal, it may implement those instructions. However, if the autonomous vehicle determines that implementing the instructions would not be safe and legal, it may execute the plan. During a training session, an autonomous vehicle may provide on a head-up display to the student certain visual feedback regarding a driving performance of the student.
US11214279B2 Controlling the operation of a head-up display apparatus
A method (900, 1000, 1200, 1300) of controlling the operation of a head-up display apparatus (302), a control apparatus (801), a system (302), a vehicle (101), a computer program (804) and a non-transitory computer readable medium (806) is disclosed. The method (900, 1000, 1200, 1300) comprises: obtaining first directional data indicative of a path of a vehicle (101, 101A, 101B); and adjusting the position of a graphical element (106) presented by the head-up display apparatus (302) in dependence on the first directional data.
US11214277B2 Control device for vehicle
A control device for a vehicle capable of switching between an automated driving mode in which driving force of a vehicle having a transmission is automatically controlled and a manual driving mode in which the driving force of the vehicle is controlled on the basis of a driver's operation on the vehicle includes: an operation element to which the driver's operation is input; and a travel control unit that outputs a command value for selecting a gear range of the transmission. The travel control unit selects which of ordinary gear change control and gear change restricting control is to be performed on the basis of an operation performed on the operation element when there is an automated driving release request in which the automated driving mode is released and the automated driving mode is switched to the manual driving mode during traveling of the vehicle in the automated driving mode.
US11214276B2 Operating method for an emergency vehicle
In an operating method for an emergency vehicle, especially a fire truck, having a vehicle body, a drive unit having a drive motor and a motor controller, front-wheel and rear-wheel pairs, an emergency aggregate, a signaling device, an illuminating device, and a mode-of-operation controller having a mode-of-operation selector switch having selectable operation modes and a memory with saved operating-data sets, by a sequence controller of the mode-of-operation controller, selecting a first operation mode corresponding to an emergency trip transmits from the memory to the target systems, and activates, first operating-data data sets. Selecting a second operation mode corresponding to an emergency mode deactivates the transmitted first operation mode operating-data sets, and transmits from the memory to the target systems, and activates, second operating-data sets. Selecting a third operation mode corresponding to a standard operation mode deactivates the transmitted data sets of the first, second or any further operation modes.
US11214274B2 Transmission schedule segmentation and prioritization
In one embodiment, a computing system receives sensor data from one or more sensors of a vehicle. The computing system determines a metric associated with the vehicle based on the received sensor data. The computing system determines, based on the metric, a length of a transmission cycle of a communication network of the vehicle. The transmission cycle comprises one or more scheduled time periods dedicated for transmitting data from respective first nodes in the communication network. The computing system configures the communication network of the vehicle based at least in part on the length of the transmission cycle to adjust respective occurrence frequencies of the scheduled time periods over multiple instances of the transmission cycle.
US11214273B2 Method of using a single controller (ECU) for a fault-tolerant/fail-operational self-driving system
In a self-driving autonomous vehicle, a controller architecture includes multiple processors within the same box. Each processor monitors the others and takes appropriate safe action when needed. Some processors may run dormant or low priority redundant functions that become active when another processor is detected to have failed. The processors are independently powered and independently execute redundant algorithms from sensor data processing to actuation commands using different hardware capabilities (GPUs, processing cores, different input signals, etc.). Intentional hardware and software diversity improves fault tolerance. The resulting fault-tolerant/fail-operational system meets ISO26262 ASIL D specifications based on a single electronic controller unit platform that can be used for self-driving vehicles.
US11214272B2 Autonomous vehicle system for determining a pullover spot in response to detected local failure
The disclosure provides for a method for determining a pullover spot for a vehicle. The method includes using a computing device to detect information related to a system of the vehicle or an environment surrounding the vehicle using a sensor of a vehicle and determine a local failure of the vehicle based on the information. The computing device may then be used to determine that the vehicle should pullover before completing a current trip related to transporting a passenger or good by comparing vehicle requirements for the trip with the local failure and determine a pullover spot by identifying a first area for the vehicle to park in part based on a second area being available for a second vehicle to pick up the passenger or good. The computing device may operate the vehicle to the pullover spot and transmit a request for a second vehicle.
US11214270B2 Systems and methods for navigating vehicles with redundant navigation systems
Systems, methods, and non-transitory computer-readable media can receive sensor data providing information about an environment surrounding a vehicle to a first computing system and a second computing system associated with the vehicle, wherein the first computing system and the second computing system are each capable of generating navigation instructions for the vehicle based on the received sensor data. A first planned trajectory is determined based on the sensor data by the first computing system. The vehicle is navigated by the first computing system based on the first planned trajectory. Control of the vehicle is transitioned from the first computing system to the second computing system based on a failure associated with the first computing system. An emulated trajectory is determined based on data describing a current motion of the vehicle by the second computing system. The vehicle is navigated by the second computing system based on the emulated trajectory.
US11214267B2 Driving assistance system
A driving assistance system includes a target sensor; an operation amount sensor; a speed sensor; and an electronic control unit. The electronic control unit is configured to perform pre-collision control when a predetermined control start condition is satisfied, and not to perform, even when the predetermined control start condition is satisfied, the pre-collision control when a permission condition has not been established by a point in time at which the predetermined control start condition is satisfied. The permission condition is that the accelerating operation amount is equal to or larger than a first operation amount threshold value and the vehicle speed is equal to or less than a speed threshold value.
US11214266B2 Vehicle telematics based driving assessment
Aspects of the disclosure relate to using vehicle telematics data to assess parameters associated with vehicle operation. In some instances, a driving assessment system may include a first computing device associated with a user in a vehicle and a second computing located remotely from the first computing device. The first computing device may collect, by way of one or more of an accelerometer and global positioning system (GPS), vehicle operational data and vehicle locational information associated with the vehicle and corresponding to a trip of the vehicle and may transmit such information to the second computing device. The second computing device may identify actionable and second order actionable trip data from the vehicle operational data and vehicle locational information and may calculate a behavior score for the trip.
US11214260B2 Method to control the execution of a shift to a lower gear with a released accelerator pedal in a drivetrain provided with a dual-clutch, servo-assisted transmission
A method to control the execution of a shift to a lower gear with a released accelerator pedal in a drivetrain provided with a dual-clutch, servo-assisted transmission; the following steps are provided: opening, in a first instant, an outgoing clutch; closing, in the first instant, an incoming clutch; completing the opening of the outgoing clutch with a first linear ramp in a second instant; synchronizing, between the second instant and a third instant, a rotation speed of the internal combustion engine with a rotation speed of the incoming clutch; closing of the incoming clutch with a second linear ramp starting from a fourth instant, which is prior to or coincides with the second instant; completing the closing of the incoming clutch in a fifth instant, which coincides with or is subsequent to the second instant; and activating the internal combustion engine so as to generate a torque between the fourth instant and the third instant.
US11214259B2 Method for managing wheel slip in a vehicle
A method of managing wheel slip in a vehicle. The vehicle has a frame, an internal combustion engine, front and rear wheels operatively connected to the engine, a throttle valve for controlling a supply of air to the engine, a steering assembly operatively connected to at least the front wheels for steering the vehicle, and an unassisted continuously variable transmission (CVT) operatively connecting the front wheels and the rear wheels to the engine. The method includes: determining a sensed deceleration of the vehicle; comparing the sensed deceleration of the vehicle to a threshold deceleration; and increasing a torque output of the engine from a current engine torque output value to an increased engine torque output value when the sensed deceleration of the vehicle is greater than the threshold deceleration. A method for managing wheel slip in accordance with a drive mode of the vehicle is also disclosed.
US11214257B2 Vehicle operation on an on-ramp
It is determined that (a) a first vehicle is driving on a curve on a first road or, (b) by detecting a second road, a road boundary of the first road. It is further determined that there is (c) parallel traffic by determining that a second vehicle is moving in a lane of the second road adjacent to the first road, or (d) tangential traffic by detecting a third vehicle is moving tangentially to the curve. Upon determining that there is simultaneously at least one of (a) the first vehicle driving on the curve on the first road or (b) the road boundary of the first road, and at least one of (c) parallel traffic or (d) tangential traffic, then it is determined that the first vehicle is driving on an on-ramp.
US11214256B2 Apparatus and method for controlling lane change in vehicle
An apparatus for controlling a lane change of a vehicle includes: a sensor to sense an external vehicle, an input device to receive a lane change command from a driver of the vehicle, and a control circuit to be electrically connected with the sensor and the input device. The control circuit may receive the lane change command using the input device, calculate a minimum operation speed for lane change control, and determine whether to accelerate the vehicle based on a distance between a preceding vehicle which is traveling on the same lane as the vehicle and the vehicle, when a driving speed of the vehicle is lower than the minimum operation speed when receiving the lane change command.
US11214250B2 Travel support device and non-transitory computer-readable medium
A travel support device including a memory that stores section information including information on a position along a traveling direction of a lane and connection information, sign information indicating contents indicated by a sign, and related information including information associating the section information with the sign information, the related information further including specifying information and regulation information, and processing circuitry that specifies a current location of a vehicle using the sign information in response to determining that the specifying information indicates that the sign can be used to specify the position of the vehicle traveling at the predetermined point, and guides the vehicle using the sign information in response to determining that the regulation information indicates that the sign contents correspond to the regulation on the vehicle traveling at the predetermined point.
US11214245B2 Vehicle control apparatus
A vehicle control apparatus includes a traveling controller and a determination unit. The traveling controller is configured to control driving force when a vehicle travels. The determination unit is configured to determine, in a case where an obstacle is detected on a road surface on which the vehicle travels, appropriateness of the vehicle passing over the obstacle. The traveling controller is configured to control the driving force of the vehicle to prevent the vehicle from passing over the obstacle in a case where the determination unit determines that it is inappropriate to pass over the obstacle.
US11214244B2 Vehicle collision avoidance control device and method for controlling same
The present disclosure provides a vehicle collision avoidance control device including: at least one first sensor configured to sense a first direction of a driver vehicle and to sense a first target vehicle in the first direction of the driver vehicle; at least one second sensor configured to sense a second direction that is opposite to the first direction of the driver vehicle and to sense a second target vehicle in the second direction of the driver vehicle; and a controller configured to output a vehicle control signal at least partially on the basis of processing of the first sensor and the second sensor, wherein the controller is configured to generate a primary vehicle control signal for avoiding a primary collision when a primary collision with the first target vehicle is predicted according to a first direction sensing result by the at least one first sensor, to modify the primary vehicle control signal into a secondary vehicle control signal on the basis of a result of sensing the second target vehicle by the at least one second sensor, and to output the secondary vehicle control signal.
US11214239B2 Driving support apparatus
A driving support apparatus is provided with: a recognizer configured to obtain information indicating a surrounding environment of a host vehicle, and configured to recognize a deceleration required target, which is a target that requires deceleration of the host vehicle; and a supporter configured to perform a driving support operation for supporting the deceleration of the host vehicle, on condition that the deceleration required target is recognized by the recognizer. If a recognition situation, which is recognized by said recognizer, of the deceleration required target that causes the driving support operation to be performed becomes uncertain while performing the driving support operation, said supporter is configured to maintain a preceding operating state of the driving support operation, which is an operating state immediately before the recognition situation becomes uncertain.
US11214233B2 Electronic key device, electronic key system, and computer readable recording medium
An electronic key device includes: a communication device; and a processor including hardware, the processor being configured to determine whether the electronic key device is in a predetermined state, excluding a stationary state and a state where the electronic key device is positioned far away from a vehicle by a predetermined distance or more, disable execution of a function of locking or unlocking the vehicle through information communication with the vehicle via the communication device when the electronic key device is in the predetermined state, and enable execution of the function when the electronic key device is not in the predetermined state.
US11214230B2 Belt guide system
A belt guide system of a vehicle guides a restraining belt between an automatic belt mechanism and a passenger area in which the restraining belt can be placed onto an occupant of the vehicle. The belt guide system includes a belt slide on which the restraining belt bears at least in part. The belt slide has a deflection region on which the restraining belt is guided to change the angle. A friction-reducing element, by which the friction of the restraining belt is reduced on the deflection region relative to the rest of the restraining belt, is provided on the deflection region.
US11214229B2 Tablet, gas generator and gas generating device and manufacturing method thereof
A tablet, a gas generator and a gas generating device are provided, wherein the tablet comprise a tablet body, the tablet body comprises opposite first and second sides, the tablet body is provided with a vent hole running from the first side to the second side, the first side is provided with a first positioning structure, and the second side is provided with a second positioning structure that cooperates with the first positioning structure. By the smart design of the tablet structure, the present disclosure can effectively simplify the structure of the gas generator and reduce the manufacturing cost.
US11214227B2 Airbag with deployment or movement controlling tensioner
An apparatus for helping to protect an occupant of a vehicle includes a curtain airbag inflatable from a stored condition adjacent a roof of the vehicle to a deployed condition in which the curtain airbag is positioned between a side structure of the vehicle and the vehicle occupant. A tensioner is positioned adjacent to the vehicle roof and spaced inboard from the vehicle side structure. A tether has a first end portion connected to the tensioner and a second end portion connected to the curtain airbag. The tensioner is configured to pay-out and/or retract the tether. The tensioner is configured to control pay-out and/or retraction of the tether to control deployment of the curtain airbag and/or to control movement of the curtain airbag once deployed.
US11214226B2 Passenger protection apparatus
A passenger protection apparatus for a vehicle includes: an inflator configured to generate gas upon receiving a predetermined actuating signal; and an airbag body folded and configured to deploy by supplying the gas from the inflator to the airbag body. The airbag body includes a predetermined area on which adhesive is applied. The predetermined area adheres to an adherend when the airbag body is deployed. An adhesive force of the adhesive is decreased by a predetermined action.
US11214225B2 Passenger protection apparatus
[Problem] To provide a side airbag apparatus capable of quickly and properly restraining a passenger in the initial stage of deploying an airbag, along with a passenger protection apparatus including this side airbag apparatus.[Resolution means] A side airbag apparatus employed in a passenger protection apparatus according to the present invention includes: an airbag for restraining a passenger when expanded and deployed; and an inflator for supplying expansion gas to the airbag. The airbag includes: a first chamber which houses the inflator and is deployed outside in the vehicle width direction of the frame side wall part; a second chamber which is deployed inside in the vehicle width direction of the frame side wall part with respect to this first chamber; and an internal expanding part which is arranged in the second chamber and expands at least on the rear side of the vehicle in the second chamber via the gas flowing out from the first chamber. In addition, the first chamber is deployed such that at least a portion thereof, as seen from the vehicle side, overlaps the frame side wall part, while the second chamber is configured to be expandable via the gas flowing out from the internal expanding part.
US11214223B2 Side airbag device
[Problem] To provide a side airbag apparatus capable of efficiently improving passenger protection performance and passenger restraining force.[Resolution means] A side airbag apparatus 100 includes: a cushion 108 which is bag shaped, wound, or folded in a storage form; a holding plate 118 with the cushion 108 attached thereto; and an inflator 110 which is embedded in the cushion 108 and attached to a side frame 112 along the side of a seat back 104 of a seat 102 together with the cushion 108 and the holding plate 118. The holding plate 118 includes: a base part 120 formed between the cushion 108 and the side frame 112; and a side wall part 122 which extends in the front-back direction of the vehicle in front of the side frame 112 in the front-back direction of the vehicle and supports the expanded and deployed cushion 108 from the side.
US11214221B2 Hard cover for side airbag
Disclosed herein is a hard cover for a side airbag. The hard cover includes a housing accommodating a cushion, a cover unit covering an opening of the housing and having a cut part formed to be cut when the cushion is deployed, a hinge connecting the cover unit and a rear of the housing, a first restraint unit provided on a front of the housing, a first hook unit provided on a front of the cover unit to be caught and restrained by the first restraint unit, a second restraint unit provided on each of upper and lower sides of the housing, and a second hook unit provided on each of upper and lower sides of the cover unit to be caught and restrained by the second restraint unit and separated from the second restraint unit when the cushion is deployed.
US11214220B2 Air bag device
An air bag device to be installed in a vehicle provided with a front seat and a rear seat disposed away from each other in a front-rear direction of the vehicle, and a reclining mechanism provided in the front seat to allow a seat back to pivot about a reclining pivot axis includes an air bag that deploys from a back surface of the seat back of the front seat toward the rear seat. At least an upper rear portion of the air bag in a deployed state is formed into an arc shape about the reclining pivot axis in a side view of the vehicle.
US11214210B2 Vehicle device with fastening system for critical areas
The invention relates to a motor vehicle device including a one-piece fastening system of the motor vehicle. This fastening system includes a fastening flange, a guiding member having at least one supporting member and a supporting surface participating in maintaining the guiding member in a first position, and an elastically deformable portion exerting a restoring force adapted to restore the guiding member into said first position.
US11214209B2 Rack of unitary one-piece construction
A rack of unitary one-piece construction for mounting to a vehicle is disclosed. The rack may be made of plastic, and may be manufactured by injection moulding. The rack may be mounted and fastened to and fastened to a truck bed. The rack protects the rear window and the roof of the truck cab when the rack is mounted to the truck bed. A connector that is received in a stake pocket and fastened to a rail of the truck bed may be used to fasten the rack to the rail of the truck bed. The injection-moulded one piece plastic rack may allow for flexibility of ease of installation and uninstallation at leisure. Line of sight from the cab through the rear window may be provided with the rack mounted to the vehicle. The load supported by the rack may be distributed to its base.
US11214208B2 Traction voltage system in a vehicle and method for controlling such a system
A traction voltage system in a vehicle includes a junction box with multiple connectors for electrical components, which components include electrical supplies and electrical loads, and an electronic control unit arranged to monitor current flowing flow to or from the components. A controller or a circuit breaker is arranged to control the supply of power to each respective component, and at least all but one of the connectors are provided with a current sensor arranged to transmit a signal representing detected current values to the electronic control unit. The electronic control unit is arranged to determine an instantaneous current value flowing to or from each component, to compare the instantaneous current value with a predetermined limit value for each connector, and to take action in response to the comparison. A method for controlling the traction voltage system is also provided.
US11214204B2 Multi-function convertible truck cargo bed liner
A single-piece foldable cargo area liner includes a floor portion, a front wall portion foldably connected to the floor portion, and a first sidewall portion foldably connected to the floor portion. A first foldable intersection portion has a first section and a second section foldably connected to the first section. The first section is foldably connected to the first sidewall portion, and the second section is also foldably connected to the front wall portion. The first foldable intersection portion is structured to facilitate folding of the first and second sections with respect to each other so as to form a first flap extending between the front wall portion and the first sidewall portion. The first flap is structured to be rotatable to enable contact between the first flap and any of the front wall portion and the first sidewall portion.
US11214202B2 Automated self-loading cargo carrier for vehicles
The invention involves a cargo carrier for vehicles that facilitates loading and unloading of items onto an enclosure; the cargo carrier may be automated and self-loading via actuators and a motorized mechanism that may be remotely controlled. The actuators may be configured to tilt the enclosure or a component thereof and one or more motors may be configured to deploy a deployable tray housed within the enclosure, which minimizes user loading or unloading labor. Typically, on a front end of the enclosure, one or more actuators may couple the enclosure to a portion of a vehicle support structure. The deployable tray may include a tiltable mechanism to further facilitate loading or unloading.
US11214199B2 Interior rearview mirror assembly with display and tilt mechanism
An interior rearview mirror assembly includes a mirror head pivotally mounted at a mirror mount, and a display device disposed in the mirror head and behind the reflective element. An actuator is disposed at the mirror head and, when actuated, pivots the mirror head upward or downward to pivot the mirror head between a mirror mode orientation and a display mode orientation. The actuator includes at least one cam follower that is pivotable and that has an arcuate groove that receives a pin at the mirror head. Actuation of the actuator pivots the cam follower to move the pin along the groove and to pivot the mirror head relative to the mirror mount. The arcuate groove of the cam follower has a spiral form having a non-uniform radius of curvature at a middle region and a constant radius of curvature about the pivot axis at each end region.
US11214196B1 Apparatus, system and method for enhanced driver vision based on road level characteristics
A system, apparatus and method for enhancing a driver's field of view in a vehicle. Sensor data may be generated, via one or more first sensors, relating a pitch angle of the vehicle and received in a processing apparatus, which further determines if the pitch angle of the vehicle exceeds a configured pitch angle threshold for a configured period of time. One or more control signals may be transmitted to activate one or more cameras configured to capture image data at least in a front area of the vehicle if the processing apparatus determines that the pitch angle exceeds the configured pitch angle for the configured period of time. The captured image data may then be displayed on a display unit.
US11214189B2 Vehicle lamp system, vehicle lamp control device and vehicle lamp control method
A vehicle lamp system includes an imaging unit which images a front of an own vehicle to generate image information, an imaging control unit which controls the imaging unit to perform an operation of generating image information with a first time period and an operation of generating image information with a second time period, a luminance analysis unit which detects luminance of individual regions in front of the own vehicle, an illuminance setting unit which determines a light distribution pattern. The illuminance setting unit, for an individual region whose luminance is within a high luminance range, sets an illuminance value such that luminance of the individual region decreases due to formation of the light distribution pattern, and for an individual region whose luminance is within a low luminance range, sets an illuminance value such that luminance of the individual region increases due to formation of the light distribution pattern.
US11214188B1 Dekhand
An illustrated view of an exemplary dekhand device for securing items while being transported is presented. The dekhand device is ergonomically shaped for easy use. Also, the dekhand device is useful for limiting the number of tools required for securing items. The dekhand device is useful for reducing arm strain. The dekhand device is useful for saving time and effort while increasing security, confidence and public safety.
US11214186B2 Hoist for vehicle with interchangeable body
Provided in this disclosure is a hoist for raising and mounting an interchangeable vehicle body onto a vehicle chassis. The hoist includes a hoist frame having a pivot end and an elevated end for slidably supporting the interchangeable body. A subframe with a bolt-on assembly is provided for fixedly connecting to the vehicle chassis. A linkage connects the hoist frame to the subframe. The linkage also includes a hinge joint member for raising the elevated end of the hoist frame. A mounting bracket pivotally connects to the pivot end of the hoist frame. The mounting bracket has a bolt-on assembly for fixedly connecting to the vehicle chassis. A winch assembly is retained in the elevated end of the hoist frame and extending to the pivot end for raising the interchangeable body onto the hoist frame.
US11214185B2 Electric vehicle
An electric vehicle includes: a vehicle main body; and a cooling box provided in the vehicle main body. A passenger compartment in which a passenger gets, and a front accommodation compartment provided more frontward than the passenger compartment are formed in the vehicle main body. The cooling box is disposed in the front accommodation compartment. Thus, the cooling box mounted on the electric vehicle can be easily accessed even when the electric vehicle is parked reversely.
US11214182B2 Headrest
A headrest includes a frame made of metal, the frame includes a base plate supported by a headrest fixing device, and a cover plate disposed on an occupant head side of the base plate. The cover plate includes a cover panel portion, and a cover frame portion extending from an outer circumferential edge of the cover panel portion toward the base plate. The base plate includes a base panel portion, and a base frame portion extending from an outer circumferential edge of the base panel portion toward the cover plate, and fitted into the cover frame portion. A first part of the cover frame portion is joined to the base frame portion, and a remaining second part of the cover frame portion is enjoined to the base frame portion.
US11214179B2 Pivoting seat assembly
A seat assembly includes a base frame supporting a lift mechanism. A seatback is operably coupled to a seat portion. The seatback and the seat portion are vertically adjustable as powered by the lift mechanism. The seat portion is pivotally coupled to the seatback by a support bracket for rotational movement between first and second positions. A seat frame of the seat portion is vertically juxtaposed over the lift mechanism when the seat portion is in the second position.
US11214175B2 System comprising a vehicle seat track and a support
A system comprising a vehicle seat track, in particular automotive vehicle, and a support, where the track comprises a fixed profile intended to be added onto the chassis of the vehicle and a mobile profile configured for sliding relative to the fixed profile. The support comprises an engaging part forming a hook, where the engaging part is configured for engaging with the mobile profile in case of impact of the vehicle.
US11214171B2 Mixed battery pack control
A vehicle system is provided with a battery and a controller. The battery includes a first module having a first capacity and a second module. The controller programmed to responsive to indication that the second module has been replaced by a new module with a second capacity that is greater than the first capacity for a corresponding state of charge (SOC), adjust a second SOC of the new module such that a maximum SOC value of the new module aligns with a maximum SOC value of the first module. The controller is further programmed to balance the first module and the new module separately.
US11214167B2 Energy supply device for a motor vehicle
An energy supply device for a motor vehicle has a high-voltage energy storage device and a control device for controlling the charging and discharging operations of the high-voltage energy storage device. The control device is designed to determine a temperature of the high-voltage energy storage device and to adjust a predetermined working range of the high-voltage energy storage device, which is defined by an upper limit and a lower limit, as a function of the determined temperature.
US11214164B2 Method and apparatus for controlling wireless power transfer to electric vehicle using bridgeless rectifier
A method for controlling wireless power transfer to an EV using a bridgeless rectifier may include detecting a phase difference between an input voltage of a transmission-side resonance circuit and an output voltage of a reception-side resonance circuit; after detecting the phase difference, predicting a resonance frequency change direction according to a preconfigured design condition; and controlling switching time points of switches included in the bridgeless rectifier in a direction compensating for the predicted change direction.
US11214160B2 System for automated charging of autonomous vehicles
The present disclosure provides a method comprising, subsequent to arrival of a vehicle at a charging station, establishing communications between a vehicle side autonomous charging system associated with the vehicle and a charging station side autonomous charging system associated with the charging station; receiving by the charging station side autonomous charging system at least one signal from the vehicle side autonomous charging system, wherein the at least one signal is indicative of a location of a charging port of the vehicle; and using the received at least one signal to guide a robotic extension arm of the charging station to a location proximate the vehicle charging port.
US11214157B2 Electric vehicle charging to reduce utility cost
A method for controlling the charging of one or more electric vehicles at one or more charging stations in a geographic locality includes determining if the charging event of an electric vehicle of the one or more electric vehicles increases a demand billing rate. The demand billing rate may be a cost per unit of energy in the locality. The method also includes charging the electric vehicle at the charging event such that the demand billing rate is not increased.
US11214156B2 Inductive charging device
An inductive charging device for an electrically operated vehicle includes a housing, at least one induction coil and at least one magnetic conductor each arranged at least partially in the housing, and a supporting structure arranged at least partly in the housing. The housing includes a bottom and a cover. The support structure includes a first structure portion and a second structure portion. The second structure portion lies at least partly against a cover portion of the cover.
US11214155B2 Device for charging at least one battery
A device for charging at least one battery has an electronics module and at least one charging pillar with a charging point. The electronics module has at least one power electronics unit having an AC/DC converter and a DC/DC converter, wherein the electronics module and the at least one charging pillar are spatially separate from one another.
US11214154B2 Battery support of modular construction
The invention relates to a battery support for an electric motor vehicle, having a tray for holding batteries, with a base and a peripheral side wall and a cover, wherein the cover is formed as a hood and the peripheral side wall is formed by a peripheral frame composed of hollow profiles, wherein the frame is coupled to a base, wherein the hood, in the closed state, is mounted on the hollow profile, and a cooling system is formed below the base, and in that a protective base is arranged below the base, in particular below the cooling system.
US11214145B2 In-vehicle GPS geo-fencing route planning, GPS proximity based advertising, infotainment system advertising and infotainment system picture or video emergency alert display
Static OEM hard-wired in-vehicle infotainment system method to capture and transmit vehicle route data for a defined geo-fenced area. Collects and transmits vehicle data to cloud server and maps geo-fenced area using GPS coordinates to produce report and vehicle route onto infotainment screen. Collective summery report and graphical display for all vehicles within a defined GPS Geo-Fenced area can also be displayed. Additional methodology includes GPS Proximity Based Advertising and Infotainment System Advertising. GPS Proximity Based Advertising defines radius around a GPS location, displaying advertisement when vehicle enters the radius. Infotainment System Advertising receives advertisement via software or firmware, onto the OEM hard-wired in-vehicle infotainment system memory. Additional methodology includes receiving and displaying emergency alert emanating from integrated public alert and warning system compliant common alert protocol alert origination tool onto static OEM hard-wired in-vehicle infotainment system, GUI to display an image, picture, video or hologram.
US11214143B2 Visually obstructed object detection for automated vehicle using V2V/V2I communications
An object-detection system for an automated vehicle includes an object-detector, a receiver, and a controller. The object-detector detects detectable-objects proximate to a host-vehicle. The receiver receives an indication of an object-presence from other-transmitters proximate to the host-vehicle. The controller is in communication with the object-detector and the receiver. The controller is configured to operate the host-vehicle to avoid interference with a hidden-object when the hidden-object is not detected by the object-detector and the object-presence is indicated by at least two instances of the other-transmitters.
US11214139B2 Motorcycle
There is provided a motorcycle which includes an engine including an exhaust port; an exhaust pipe connected to the exhaust port of the engine; and a catalyst disposed within the exhaust pipe. The exhaust pipe includes a catalyst case accommodating the catalyst, and a pipe connecting the exhaust port of the engine and the catalyst case. The catalyst is disposed in front of the engine. An occupied area of the catalyst in a direction orthogonal to a flow direction of exhaust gas is larger than an opening area of the pipe in a direction orthogonal to a flow direction of exhaust gas. A central axis of the catalyst is inclined with respect to a vehicle width direction in a vehicle front view. And the central axis of the catalyst and a center line of the engine in the vehicle width direction intersect at a position overlapping with the catalyst in the vehicle front view.
US11214138B2 Utility vehicle
Provided is a utility vehicle that can efficiently take the traveling wind into a vehicle and discharge muddy water and earth and sand that enter a passage for taking in the traveling wind to the outside of the vehicle. The utility vehicle includes an opening formed on the vehicle body, the opening through which a traveling wind can be taken into the vehicle body when the vehicle body travels, a radiator capable of cooling a coolant for cooling a driving source by exchanging heat with the traveling wind taken in from the opening, a passage that is provided between the opening and the radiator and guides the traveling wind taken in from the opening to the radiator, and a discharge mechanism that performs discharge operation to discharge foreign matter to outside when the foreign matter enters inside of the passage together with the traveling wind.
US11214134B2 Linkage flap arrangement and convertible vehicle having a linkage flap arrangement
A linkage flap arrangement of a convertible vehicle is provided, having a blind arrangement that may have a first blind and a second blind that can be driven using a common drive. The first blind, upon an actuation of the common drive, performs a pivoting movement between a covering position and a cleared position and the second blind performs a translatory movement via a coupling between the first blind and the second blind.
US11214130B2 Glazing for motor vehicles
The invention relates to a laminated glass panel for an automobile, having a curved shape resulting from the assembly of a first glass sheet, which is curved before said assembly, with an intermediate thermoplastic sheet and a second glass sheet, the thickness of which does not exceed one third of that of the first sheet, the second glass sheet not being curved, or having a curvature that is substantially smaller than that of the first sheet before the assembly thereof with the latter and the intermediate thermoplastic sheet.
US11214129B2 Windshield and windshield manufacturing method
A windshield according to an aspect of the present invention is a windshield for an automobile on which an information acquisition device capable of acquiring information from the outside of a vehicle by emitting and/or receiving light can be arranged. The windshield includes; a glass plate including an information acquisition region that is opposite to the information acquisition device and through which the light passes; and an antifog laminate that includes a heat blocking layer and an antifog layer with antifog properties layered on one surface of the heat blocking layer, and that is layered on a surface on a vehicle interior side of the information acquisition region while the other surface of the heat blocking layer faces the surface on the vehicle interior side of the information acquisition region.
US11214128B2 Air nozzle device for a vehicle
The present invention relates to an air nozzle device for a vehicle comprising a housing defining an interior volume and having an air inlet at one side, an air discharge opening at a second side and an air flow channel through the housing for transporting a flow of air between the air inlet and the air discharge opening, the device further comprising an air flow regulator mechanism comprising a rod member comprising a rack, at least one flap member comprising a pinion, and an assembly guide mechanism arranged to be moveable between an assembly position and a non-assembly position, wherein the rack and pinion is arranged to, in an assembled state, interact to rotate the at least one flap member about an axis between an open and a closed position to regulate the flow of air in the air flow channel, the assembly guide mechanism is, in the assembly position, arranged to interact with the at least one flap member and the rod member to assemble the rack and pinion, and the assembly guide mechanism is, in the non-assembly position, arranged to obstruct the assembly of the rack and pinion.
US11214124B2 Extraction device for a motor vehicle
An extraction device is provided for a motor vehicle, in particular for a motor bike or for a motor vehicle similar to a motor bike. The extraction device includes at least one duct-like air-guide which has at least one opening which is arranged in or at an exhaust-air region of a ventilated vehicle component of the motor vehicle, such as engine, gearbox or the like, and which is extended between the used-air region of the vehicle component and a rear wheel of the motor vehicle, and at least one suction apparatus which is connectable or is connected to the air-guide and in which a negative pressure can be produced in order to suck air out of the exhaust-air region via the at least one air-guide.
US11214123B2 Electric auxiliary heating device
The present invention relates to an electric auxiliary heating device (1) for heating a flow of air passing through in particular a conduit of a ventilation, heating and/or air conditioning installation of a motor vehicle, the auxiliary heating device comprising a casing that houses at least one heating module, said casing comprising: ∘a heating compartment of which a first end (61) comprises an opening (600) and ∘a connection interface (8) comprising: ▪a first plate (86) that is essentially planar and extends essentially parallel to the opening so as to cover said opening, and ▪a sheath (88) that extends in projection from the first plate (86) opposite the heating compartment, ▪slots (80) passing through the first plate (86) and opening inside the sheath (88), the connection interface (8) comprising, on its internal face (89) that is oriented toward the heating compartment, at least one insertion stub (85) of which at least one of the edges facing the slots (80) is chamfered.
US11214120B2 Distributed fiber optic sensing system
A disclosed vehicle sensing system includes an optic fiber disposed adjacent to a vehicle panel, a transmitter/receiver disposed at an originating end of the optic fiber, the transmitter/receiver configured to emit a beam through the optic fiber at a defined originating frequency, and a reflector disposed at a terminal end of the optic fiber for reflecting the beam back through the optic fiber to the transmitter/receiver. Dimensional changes to the optic fiber change the originating frequency reflected back to the transmitter/receiver and the change in the originating frequency is indicative of a physical change in the vehicle panel.
US11214119B2 Methods and apparatus for vehicle HVAC control using portable devices
Methods and apparatus for vehicle HVAC control are disclosed. A disclosed example apparatus includes a portable device interface of a vehicle, the portable device interface to be communicatively coupled with a portable device, a heating, ventilation and air conditioning (HVAC) control system of the vehicle, where the HVAC control system is to be communicatively coupled to the portable device interface. The example apparatus also includes a processor to control the HVAC control system based on signals received at the portable device interface from the portable device.
US11214115B2 Temperature management systems and methods for electric vehicle
A temperature control system for an electric vehicle includes a cabin temperature control system configured to control flow of a refrigerant through one or more heat exchangers to control a temperature of a cabin of the electric vehicle, a battery temperature control system configured to control the flow of a coolant through one or more heat exchangers to control a temperature of a battery system of the electric vehicle, and a power electronics temperature control system configured to control the flow of coolant through one or more heat exchangers to control a temperature of one or more power electronics. In a first configuration of the temperature control system, the battery temperature control system and the power electronics temperature control system may be thermally isolated, and, in a second configuration, the battery temperature control system and the power electronics temperature control system may thermally interact.
US11214114B2 Electric vehicle thermal management system
A traction battery thermal management system is provided. The thermal management system includes a battery loop for regulating the traction battery temperature. A motor loop is provided for regulating a motor temperature. The thermal management system also includes a radiator. A radiator valve selectively controls fluid flow through the radiator. A battery valve selectively couples the battery loop and the motor loops. The battery loop, the motor loop are in fluid communication and arranged in parallel to be cooled by the radiator.
US11214113B2 Vehicular air conditioning device
A vehicular air conditioning device includes an air conditioning case having first, second case introduction ports and first, second case discharge ports, and a fan. The first, second case discharge ports are offset upward and downward in an up-down direction relative to a rotation axis, respectively. A first inner guide surface of an inner guide plate is located on the one side of a second inner guide surface in the left-right direction. Air introduced through the first case introduction port is guided by the first inner guide surface to be drawn from a first passage into the fan, the air being blown upward to flow through the first case discharge port. Air introduced through the second case introduction port is guided by the second inner guide surface to be drawn from a second passage into the fan, the air being blown upward to flow through the second case discharge port.
US11214110B2 Working machine and a method for suspending a working machine
The invention relates to a working machine comprising a working machine frame, at least one propulsion axle having an elongated main body comprising a first end portion, a second end portion and a center portion arranged between the first and second end portions. The elongated main body has a main body length (MBL) extending from the first end portion to the second end portion. The working machine further comprises a propulsion axle suspension arrangement arranged between the working machine frame and the propulsion axle, the propulsion axle suspension arrangement comprising a first suspension device and a second suspension device arranged on opposite sides of a center of the elongated main body. The first and second suspension devices are arranged in the center portion of the elongated main body.
US11214109B2 Vehicle suspension arm
A vehicle suspension arm includes: a wheel support portion which supports a wheel through a ball joint serving as a joining member; a front side vehicle body installation portion serving as a vehicle body installation portion which is installed in a vehicle body; and a wheel side portion which joins the wheel support portion to the front side vehicle body installation portion. The wheel side portion includes an offset portion, which has a cross-sectional shape with a gravity center being offset upward or downward from a straight line that connects the ball joint to the front side vehicle body installation portion.
US11214108B2 Suspension system for vehicle
A suspension system for a vehicle may include a knuckle configured of rotatably supporting a wheel, and a lower control arm mounted along a vehicle's width direction and connecting the knuckle and a vehicle body, wherein the lower control arm may include a wheel-side end portion connected to a lower portion of the knuckle through a lower external joint, a vehicle body-side front end portion connected to the vehicle body through a front lower inner joint, and a vehicle body-side rear end portion connected to the vehicle body through a rear lower inner joint, wherein one of the vehicle body-side front and rear end portions is connected to a portion of the vehicle body through a compliance control arm.
US11214107B2 Vehicle front-end assembly
A vehicle front-end assembly includes a vehicle frame, a first tow hook and a skid plate. The first tow hook has a forward portion and a rearward portion. The rearward portion of the first tow hook is attached a front-end portion of a first front side member of the vehicle frame by a mechanical fastener. The skid plate has a main section and a first attachment flange that extends from the main section. The first attachment flange is attached to the front-end portion of the first front side member by the mechanical fastener. The first attachment flange has a first alignment projecting surface. During installation of the skid plate to the first front side member, the first alignment projection contacts a surface of the rearward portion of the first tow hook moving the first tow hook into alignment with the first front side member.
US11214106B2 Pivoting trailer hitch
A trailer coupling mechanism includes a first end, a second end, a height adjustment assembly, a first swivel assembly, and a second swivel assembly. The first end is adapted to couple to one of a trailer and a vehicle. The second end is adapted to couple to the other of the trailer and the vehicle. The height adjustment assembly is coupled between the first and second ends and is operative to adjust the relative height between the first and second ends. The first swivel assembly is coupled between the height adjustment assembly and the first end and facilitates rotation of the first end with respect to the height adjustment assembly about a first axis. The second swivel assembly is coupled between the second end and the height adjustment assembly and facilitates rotation of the height adjustment assembly with respect to the second end about a second axis parallel to the first axis.
US11214104B2 Gearbox brake trailer apparatus
A gearbox brake trailer apparatus for safe downhill towing includes a frame having a front end, a left side, a right side, and a rear end. The front end has a trailer hookup configured to selectively engage a trailer hitch of a truck. A trailer deck is coupled to the frame. Each of a plurality of wheel pairs has an axle rotatably coupled between the left side and the right side of the frame and a pair of tires coupled to the axle. A gearbox is coupled to the frame and has a wiring harness configured to selectively engage with an electrical control plug of the truck. A drive linkage is coupled to the gearbox and is in operational communication with the gearbox and with the axle of a front most wheel pair of the plurality of wheel pairs to brake the rotation of the front most wheel pair.
US11214103B2 Method for mounting and demounting a tyre to and from a wheel rim
The invention relates to a method for mounting/demounting a tyre (T) on a rim (R). The method comprises the steps of: determining an initial reference position for the mounting/demounting device (U1, U2), said initial reference position being proximal to an edge (E) of the wheel rim (R); linking the position of the mounting/demounting device (U1, U2) with the initial reference position; adjusting the position of the mounting/demounting device (U1, U2) with respect to either the first or the second direction; continuously detecting the position of the mounting/demounting device (U1, U2) with respect to said either first or second direction; and continuously and automatically adjusting the position of the mounting/demounting device (U1, U2), with respect to the other one of said either first or second direction, at least in dependence of the initial reference position.
US11214101B2 Pneumatic tire
A pneumatic tire according to the present technology is a pneumatic tire provided with a tread section, sidewall sections, and bead sections, a belt-shaped sound-absorbing member being bonded via an adhesive layer to an inner surface of the tire in a region corresponding to the tread section along the circumferential direction of the tire, wherein a bonding surface of the sound-absorbing member is provided with a bonded region that is bonded to the inner surface of the tire and an unbonded region that is not bonded to the inner surface of the tire, and the bonded region is divided by the unbonded region into a plurality of divisions along the circumferential direction of the tire.
US11214098B2 Pneumatic tire
A pneumatic tire includes at least four circumferential main grooves extending in a tire circumferential direction and at least five land portions defined by the at least four circumferential main grooves. A center land portion includes a plurality of center lug grooves extending through the center land portion in a tire lateral direction and disposed at predetermined intervals in the tire circumferential direction, and a plurality of center blocks that are defined by the plurality of center lug grooves. The center blocks each include a narrow shallow groove that extends through the center block in the tire lateral direction and that remains open when the tire comes into contact with the ground.
US11214091B2 Secure packs for transaction cards
A secure packaging system for a stored value card. The secure packaging system including a front panel and a back panel sealed via a non-rewettable polymer to the front panel at a non-rewettable sealing section, the sealing section arranged continuously around at least a periphery of the stored value card, wherein the sealing section cannot be reactivated or unsealed with heat to access the contents therein.
US11214090B1 Binding device and method of using
A binding device and method that allows pages or documents to be secured in a binder while providing a recyclable, transparent and printable cover. The binding device includes a flexible sheet having a front surface, a rear surface, a first, second, third and fourth edge, a fold parallel to the first edge on the flexible sheet that extends from the second edge to the fourth edge, a plurality of spaced apart die cuts adjacent the fold shaped to form tabs, a transparent flexible front cover having a front surface, rear surface, a first, second, third and fourth edge, the first edge of the front cover overlapping and affixing to the front surface of the flexible sheet.
US11214087B2 Automatic drawing system and method of operating automatic drawing system
An object of the present invention is to provide an automatic drawing system capable of drawing a figure having a smooth and clear contour, in which a control apparatus, based on figure data of a planned drawing figure, by operation of a cartesian coordinate robot, moves a paint discharging apparatus parallel to a contour line of the planned drawing figure to be drawn at a planned drawing location, and along with this movement, the control apparatus executes contour parallel drawing control that causes the paint discharging apparatus to continuously perform a paint discharging operation, thereby drawing a contour portion of the planned drawing figure.
US11214084B2 Recording apparatus
A recording apparatus includes a recording section that performs recording on a medium, a housing that houses the recording section, a tray configured to move to a loading position in which to load the medium to be subjected to recording and ejected and a stowage position in which the tray is stowed in the housing, and a switching unit that switches between an automatic mode in which to automatically move the tray to the loading position and the stowage position and a manual mode in which to manually move the tray to the loading position and the stowage position.
US11214083B2 Stepper motor-based print adjustments
In one example in accordance with the present disclosure, a printing system is described. The printing system includes a media sensor to detect a presence of media at a particular point within the printing system. A stepper motor moves media through the printing system. A controller 1) monitors, for at least one pass of the media, a number of steps of the stepper motor to pass the media between the media sensor and a print position, 2) stores the number of steps of the stepper motor in a memory device, and 3) adjusts operation of subsequent passes of the media based on stored number of steps. A memory device of the printing system stores the number of steps of the stepper motor, for at least one pass of the media.
US11214073B2 Printing apparatus and a liquid circulation method in a printing apparatus
The liquid L flowed into the bypass communication pipe 93 from the feed reservoir 91f can be returned to the feed reservoir 91f by way of the return reservoir 91r by carrying out the bypass circulation of circulating the liquid L along the bypass circulation channel Cb. Since this bypass communication pipe 93 bypasses the discharge heads H, the liquid L does not pass through the discharge heads H in the bypass circulation. As a result, the liquid L can be circulated between the feed reservoir 91f and the return reservoir 91r while the mixing of foreign substances into the discharge heads H from the respective reservoirs 91f, 91r is suppressed.
US11214071B2 Printer and ink supply unit
A printer is provided that includes a first ink storage unit storing ink, a second ink storage unit storing ink supplied from the first ink storage unit, a discharge head configured to discharge ink, a carriage configured to move the discharge head and the second ink storage unit, and a tube coupling the first ink storage unit and the second ink storage unit. The second ink storage unit includes an ink supplying port to which the tube is coupled, a communication hole communicating making inside and outside of the second ink storage unit communicate with each other, and a light-transmissive surface which is transparent or translucent. The communication hole and a portion of the light-transmissive surface are located at a position vertically higher than a front surface of the carriage in a state where the second ink storage unit is mounted on the carriage.
US11214068B2 Printhead servicing
There is provided a maintenance apparatus to, while in a service zone, perform a cleaning operation of a set of printheads within a carriage. The maintenance apparatus comprises a cleaning structure and an actuation mechanism. The actuation mechanism is arranged to position the cleaning structure between an engaged configuration and a disengaged configuration. The disengaged configuration is activated by a first triggering element associated to the carriage interacting with the actuation mechanism subsequent to a cleaning operation. The engaged configuration is activated by a second triggering element as the carriage moves away from the service zone.
US11214066B2 Recording device and recording head error determining method
A recording device includes a recording head including a plurality of nozzle rows of a plurality of nozzles for ejecting a same color ink, a detector configured to detect, from among the plurality of nozzles, a defective nozzle having an ejecting defect, and a control unit configured to determine whether the recording head is in an error state, based on a detection result from the detector. The control unit determines that the recording head is in the error state when, among the plurality of nozzles having a specific positional relationship in which the nozzles are configured to compensate for each other's ejection, at least a predetermined number the nozzles, which is greater than one, is the defective nozzle.
US11214062B2 Liquid discharging apparatus
A liquid discharging apparatus includes: a drive unit that includes a discharging head that discharges liquid; a first board that includes a control circuit that controls the discharging head; a first cable for electrical coupling between the control circuit and the drive unit; a second cable for electrical coupling between the control circuit and the drive unit; and housing inside which the drive unit, the first board, the first cable, and the second cable are housed. The second cable includes a shield layer containing a conductive material. The position of the first cable is between the housing and the second cable.
US11214061B2 Microfluidic MEMS device with piezoelectric actuation and manufacturing process thereof
The microfluidic device has a plurality of ejector elements. Each ejector element includes a first region, accommodating a first fluid flow channel and an actuator chamber; a second region, accommodating a fluid containment chamber; and a third region, accommodating a second fluid flow channel. The fluid containment chamber is fluidically coupled to the first and to the second fluid flow channels. The second region is formed from a membrane layer, from a membrane definition layer, mechanically coupled to the membrane layer and having a membrane definition opening, and a fluid chamber defining body, mechanically coupled to the membrane definition layer and having a chamber defining opening, with a width greater than the width of the membrane definition opening. The width of the membrane is thus defined by the width of the chamber defining opening.
US11214060B2 Gaps between electrically conductive ground structures
In some examples, a fluid dispensing die includes a plurality of fluid actuators to cause dispensing of a fluid from respective nozzles of the fluid dispensing die, and an electrically conductive layer including electrically conductive ground structures to connect respective fluid actuators of the plurality of fluid actuators to a ground, wherein the electrically conductive layer includes gaps provided between the electrically conductive ground structures of the electrically conductive layer.
US11214056B2 Driver circuit
A driver circuit for receiving a voltage supply at a supply input and driving a load through a load output, the circuit comprising: a charge inductor and a discharge inductor; a switching array comprising a plurality of switches; and a load switch coupled between a first terminal of the charge inductor and the load output; the switching array being arranged so that: in a first mode it can couple a second terminal of the charge inductor to the supply input and the first terminal of the charge inductor to ground to load a flux on the charge inductor; in a second mode it can decouple the first terminal of the charge inductor from ground so that, when the load switch is closed, flux can flow from the inductor to the load output; and in a third mode it can couple the discharge inductor between the load output and ground so that flux can be loaded on the discharge inductor from the load output.
US11214055B2 Actuator drive circuit with trim control of pulse shape
A drive circuit (100) for driving actuators of a printhead (97) from a common drive waveform has a switching circuit (32) for coupling the common drive waveform to an actuator (1,2), and a timing circuit (10) to control the switching circuit to form a drive pulse from the common drive waveform. The drive pulse is trimmed by controlling a duration (TTRIM) of a step at an intermediate level (VHOLD) in the drive pulse. This can improve the trade-off between available range of trimming and thermal efficiency because the voltage drop across the switching circuit can be reduced, compared to trimming only the height. Decoupling during a flat portion of the common drive waveform can enable the timing of the decoupling to be more relaxed compared to decoupling during a slope. Such relaxing can enable costs, complexity and thermal loading to be reduced.
US11214054B2 Sheet-fed printing machine for different printing methods
A sheet-fed printing unit has a first impression cylinder and a second impression cylinder, which are arranged directly and interactingly in contact and which each have an axis of rotation. An axial plane contains the axes of rotation. A reference plane is a plane which contains an axis of rotation of a cylinder of this type and has a horizontal surface normal. These two cylinders are arranged such that an intersection angle between the axial plane and the reference plane is a maximum of 15°. A transport path is provided for a transportation of sheets, which transport path has a region for the respective impression cylinder in which there is contact between sheets and a casing surface. This region of the transport path for the respective impression cylinder extends over an angular range of at least 270°. A sheet-fed printing machine has a sheet-fed printing unit of this type.
US11214044B2 Multilayer film comprising polyalkylene carbonate and manufacturing method of the same
The present disclosure relates to a multilayer film including polyalkylene carbonate, and more particularly to a multilayer film including a core layer prepared by blending polyalkylene carbonate and an ethylene vinyl acetate copolymer in a predetermined ratio, and an outer layer of polyolefin. The multilayer film does not have delamination behavior because two layers are adhered each other with a simple process without an additional step for introducing an oxygen-barrier layer even without adhesive or tie layers, and has an excellent oxygen barrier property. In addition, since an additional process for imparting barrier properties and a separate adhesive or tie layer are not required in the manufacturing method, the cost can be reduced and the layer structure can be simplified, which may greatly reduce the manufacturing cost.
US11214043B2 Intermediate film for laminated glass, and laminated glass
Provided is an interlayer film for laminated glass capable of effectively enhancing the sound insulating property of laminated glass having the interlayer film, in the interlayer film including a layer prepared with a thermoplastic component other than a polyvinyl acetal resin. An interlayer film for laminated glass according to the present invention has a one-layer structure or a two or more-layer structure, and includes a thermoplastic elastomer layer containing a thermoplastic elastomer and a plasticizer, and the thermoplastic elastomer is an aliphatic polyolefin, the thermoplastic elastomer layer has a glass transition temperature in a temperature range of −10° C. to 10° C., and a maximum value of tan δ in a temperature range of −10° C. to 10° C. of the thermoplastic elastomer layer is 1.5 or more.
US11214040B2 Resin molded body
A resin molded body includes a body having a surface, and a decorative sheet adhered to the surface of the body. The decorative sheet has a metallic luster layer, a transparent protective layer positioned on an outer side of the metallic luster layer, and a welding layer adhered to the surface of the body. The body is formed from a fiber-reinforced resin having reinforcing fibers defining an anchor structuring layer such that the reinforcing fibers of the body bite into the welding layer at a boundary portion between the welding layer and the body such that the boundary portion has an uneven shape.
US11214039B2 Process for manufacturing textured laminate sheet
A process for producing a textured laminate sheet includes a) positioning a substrate material adjacent a barbed face of a metal sheet. The barbed face has a plurality of barbs, and the metal sheet has an opposed face opposite the barbed face. The process further includes b) forcing the metal sheet and the substrate material together to impale the substrate material on the barbs and secure the substrate material and the metal sheet together as a laminate sheet, and c) debossing the opposed face to form a plurality of depressions in the laminate sheet and texture the laminate sheet.
US11214038B2 Wavelength conversion sheet protective films and methods of producing the same, wavelength conversion sheets and backlight units
The present invention provides a wavelength conversion sheet protective film having a structure in which a first film, which includes a first substrate and a first barrier layer, and a second film, which includes a second substrate, are bonded to each other at a surface of the first barrier layer and one surface of the second substrate via an adhesive layer, wherein a thermal expansion coefficient in a TD direction in a temperature range of 30 to 90° C. is about 1.0×10−4/K or less.
US11214035B2 Marine decking with sandwich-type construction and method of making same
A marine deck member and the process for forming the same. The marine deck member comprises a sandwich-type composite panel made by a compression molding process. In such a process, the panel is made by subjecting a heated stack of layers of material to cold-pressing in a mold. The cellular core has a 2-D array of cells, with end faces open to the respective layers or skins. The surface traction of this type of composite panel can be enhanced for marine deck applications by controlled debossing, or embossing, of the first skin while it cools in the compression mold. The debossing effect can be affected by applying pressurized gas, e.g., pressurized air, onto the outer surface of the first skin while in the compression mold. The embossing can be affected by applying vacuum pressure on the outer surface of the first skin while in the compression mold.
US11214034B2 Seals for stretchable films
In one example, a plastic product such as a plastic bag includes one or more seals. One of the seals includes respective portions of first and second plastic films that are arranged one on top of the other. The respective portions are joined together and are aligned generally parallel to a direction of elongation associated with the plastic films, where the direction of elongation is a direction in which the plastic films elongate when under load. As well, the respective portions extend along a length of the joined plastic films and have a length that is greater than a length of the plastic films.
US11214032B2 Box template production system and method
A method and a box template production system comprising a converting part which is configured for converting a fanfolded sheet material into box templates, wherein said converting is accomplished to the sheet material when a feed direction of the sheet material through the converting part of the system is along an axis having an angle towards a plane of a floor onto which the system stands, wherein said angle is between 20 and 90 degrees.
US11214027B2 Process for the multi-stage production of a traction or carrying means
A process for the production of a traction or carrying means built up from a plurality of components or assemblies of extruded elastomeric material, wherein, in a first substep, a first component, provided with reinforcing members or cables, of the traction or carrying means is produced and, in further substeps, a traction or carrying means, which is connected to further components or provided with further layers of elastomeric material, fabric layers or reinforcing-member layers, is successively completed, and optionally said traction or carrying means is shaped on one or more sides, wherein the individual substeps follow one another such that a component processed or completed in the respectively preceding substep is fed at room temperature (Rt), after a maximum of 1 to 10 minutes, to the subsequent substep, and such that the temperature of the component does not drop below 30° C. between a respectively preceding substep and the subsequent substep.
US11214025B2 Fibre-reinforced components
A method for forming a composite component, comprising: locating a rigid composite element comprising a matrix interspersed with long fibre reinforcement in a mould that is shaped to define a cavity about the rigid element; loading a material comprising a matrix precursor interspersed with short fibre reinforcement into the cavity; and curing the matrix precursor.
US11214024B2 Method for forming three-dimensional structures with different material portions
A system and method for forming 3D printed structures includes printing an outer shell portion and filling an interior of the outer shell portion to form an inner portion. The outer shell portion and inner portion may have differing material properties. The outer shell portion may be anchored to the base component.
US11214020B2 Fabrication method and apparatus for creating large and/or complex thermoplastic composite components
This disclosure is directed to a thermoplastic composite material forming method and tooling used to perform the method. More specifically, this disclosure is directed to a method of fabricating large, complex thermoplastic composite part shapes with a consolidation tool having a conformable tooling bladder that heat thermoplastic material in the tool and provide thermoplastic material consolidation pressure in directions in the tool to form a part shape of thermoplastic composite material. A novel tooling concept is used to fabricate large, complex thermoplastic composite part shapes which are not easily producible using traditional methods. The tooling concept employs a consolidation tool that provides a method to apply thermoplastic material consolidation pressure by a conformable tooling bladder that provides thermoplastic material consolidation pressure in directions in the tool that are not achievable by conventional clamshell type molds where the mold parts move in substantially vertical tool opening and tool closing directions.
US11214019B2 Surface engineering of thermoplastic materials and tooling
A prepared mold tool having a thermoplastic surface layer polymer coating on the mold surface of the mold tool or prepared prepreg having a thermoplastic surface layer polymer coating on the surface of the thermoplastic fiber reinforced prepreg are described that enhance first ply laydown of thermoplastic fiber reinforced composite prepregs onto mold tools for prepreg forming or in situ tape placement. Resulting thermoplastic fiber reinforced composite parts from a thermoplastic fiber reinforced thermoplastic composite material having structural reinforcement fibers with one or more high performance polymers, and a thermoplastic surface layer polymer coating which forms a polymer blend with the high performance polymers of the thermoplastic fiber reinforced composite material thereby imparting improved properties, and methods for making and using same, are provided herein.
US11214015B2 Methods and systems for controlling temperature across a region defined by using thermally conductive elements
An approach is provided for separating a selected component from a plurality of components in a multi-component medium. A multi-component medium is created, including thermally conductive layer into which a template of patterned thermally conductive elements that are thermally separated from each other, a thermally active adhesion layer in thermal communication with the thermally conductive template, and a set of components attached to the thermally active adhesion layer in substantially the same pattern as thermally conductive template. The medium allows a selected component to be released by applying energy to a selected thermally conductive element corresponding to the selected component, inducing a temperature differential reducing the adhesion of the thermally active adhesion layer, without releasing non-selected components.
US11214012B2 Ultrasonic welding method, structure welded by ultrasonic welding method, and ultrasonic welding device
A pair of thermoplastic resin members are placed on an anvil. A pressing force of a tool horn vibrating ultrasonically in a direction not perpendicular to but along upper surfaces of the pair of thermoplastic resin members is applied to the upper surfaces. The application of the pressing force of the tool horn vibrating ultrasonically allows melting of a vicinity of the upper surfaces of the pair of thermoplastic resin members. A welded structure part is formed on an unwelded structure part, thereby welding the pair of thermoplastic resin members as an overlap structure including the welded structure part arranged on the unwelded structure part. The distance and positional relationship between the pair of thermoplastic resin members after the welding are unchanged before and after the welding. The surfaces, placed on the anvil, of the thermoplastic resin members are neither burned nor discolored.
US11214011B2 Method and sealing device for sealing the edges of composite fiber components
A sealing device for sealing edges of composite fiber components includes a strip feeder to apply a thermoplastic semifinished product to a cut edge of a composite fiber component, and an ultrasonic welding apparatus to thermoplastically or integrally join the thermoplastic semifinished product to the cut edge of the composite fiber component by ultrasonic welding.
US11214006B2 Methods and apparatus for additive manufacturing utilizing multifunctional composite materials, and articles made therefrom
A method of depositing a multiphase material. The method includes providing a Continuous Multifunctional Composite (CMC) phase containing at least one continuous element in a polymeric matrix, passing the CMC phase through a feeding system containing a cutting system, producing a predetermined length of the CMC phase, providing a flow a molten polymer such that the molten polymer and the CMC phase are merged into a continuous co-extrusion nozzle so as to produce a co-extruded multiphase material, and depositing the co-extruded multiphase material onto a surface. An apparatus for depositing a multiphase material. The apparatus contains a co-extrusion nozzle, a means to introduce a CMC phase and a molten polymer into the co-extrusion nozzle, such that the molten polymer and the CMC phase are co-extruded and deposited on a surface. An article containing a CMC phase containing continuous elements embedded in a polymer resin forming a multiphase structure.
US11214004B2 Build compartment with self-sealing design
The present invention relates to a build compartment used in 3D printing systems based on powder beds. The build compartment is the volume in a 3D printing apparatus where 3D objects are formed by successive consolidation of thin layers of powder. The build compartment is designed with at least two vertical wall structures movable in relation to each other. The movable wall structures are at least partly overlapping in the movable direction, providing self-sealing for a variable volume for enclosing powder. Contrary to other available designs, this solution does not need a compressible sealing material, for example an elastomer, a textile felt or a braided rope, to prevent powder leakage from the build compartment. The advantages are more reliable sealing and no risk of contamination of the powder by debris from sealing material.
US11214002B2 Additively manufacturing of amorphous structures
An additive manufacturing system configured to additively build an article can include an energy applicator, a build platform, and a powder nozzle configured to eject powder toward the build platform to be acted on by the energy applicator. The system can include a control module configured to control the energy applicator to create an amorphous structure forming at least a portion of the article.
US11214001B2 Fusion inhibiting agents with colorants
In an example, a method includes providing a build material. Print agent comprising colorant may be applied to a first portion of the build material to be fused in additive manufacturing, wherein the print agent is applied according to a target color for the first portion. A combination of a fusion inhibiting agent and colorant may be applied to a second portion of the build material, wherein the print agent is applied according to the target color of the first portion and the second portion is adjacent to the first portion. The method may further include heating the build material by exposing the build material to radiation so as to cause fusing of the first portion.
US11214000B2 Apparatus and method for fabricating multi-sided printed composite sheet structures
An additive manufacturing system for fabricating multi-sided printed composite sheet structures includes a roll fed duplex architecture that prints polymer images on both sides of a substrate sheet to form two-sided 3D composite layers. A substrate web is fed into the machine, and a top side is printed with a wetting agent, powdered, and the excess powder is removed. The image may be pinned to the substrate in a fusing step so that the web can be inverted to print a second image on the other side. The inversion architecture could include inverting rollers, tubes or a Mobius strip that may flip the substrate for backside printing using a single imaging station. The resulting two-side powdered and pinned substrate would then be cut, stacked, heated and compressed to create a 3-D object with more polymer in the stack, resulting in better adhesive binding characteristics at a much higher production speed.
US11213998B2 Liquefier assemblies for additive manufacturing systems, and methods of use thereof
A liquefier assembly for use in an additive manufacturing system to print three-dimensional parts. In one aspect, the liquefier assembly includes a liquefier that is transversely compressible, and having an inlet end configured to receive a consumable material in a solid or molten state and an outlet end, a nozzle at the outlet end, and an actuator mechanism configured to transversely compress and expand the liquefier in a controlled manner In another aspect, the liquefier assembly is self heating.
US11213994B2 Method and forming tool for hot-forming a flat thermoplastic laminate
A flat laminate element made of thermoplastic is hot-formed in a two-stage method. In a first stage, the flat laminate which includes film(s) and/or panels(n) is placed on a flat frame-shaped pallet and is heated to a forming temperature in a heating zone between two flat heat screens in a contactless manner. The edge zone of the hot flat laminate element lies on the pallet such that the laminate piece cannot be clamped in a first laminate direction but rather can be slide on the pallet in this direction. Two non-flat rigid contours which are identical or largely identical act on two opposing parallel laminate edge sections uniaxially and perpendicularly to the laminate plane and only in the first laminate direction, i.e. monodirectionally, and shape the entire heated laminate element into a monodirectionally molded blank.
US11213992B2 Composite preform, method for manufacturing same, composite container, method for manufacturing said composite container, and heat shrinkable plastic member
A method for manufacturing a composite preform is provided, including preparing a preform that is formed from a plastic material, preparing a tubular heat shrinkable plastic member that is longer than the preform and has a margin for thermocompression bonding at one end, inserting the preform into the plastic member having the plastic member undergo thermal shrinkage by heating the preform and the plastic member, and bonding the margin of the plastic member by thermocompression.
US11213989B2 Downhole probe sleeves and methods for making probe sleeves
A downhole probe of a drilling rig has a probe sleeve for protecting the downhole probe. The probe sleeve may be made of a metal or a polymer such as polyphenylene sulfide. The probe sleeve may be heat-shrinkable to provide a tight fit between the downhole probe and the probe sleeve. The probe sleeve may include one or more protrusions shaped to engage a centralizer surrounding at least part of the downhole probe. The one or more protrusions may be arranged to prevent rotation of the centralizer relative to the probe sleeve. The probe sleeve may be made using a modified extrusion process and may include reinforcement to add strength to weld-lines along the length of the probe sleeve. The protrusions may also be used as reinforcement.
US11213988B2 Methods and machines for making oral products
A method of forming an oral product includes extruding a mixture, conveying the extruded mixture through one or more pairs of forming rollers, and cutting the extruded mixture into one or more oral products. The mixture can include polymer and at least one flavorant, sweetener, active ingredient, or combination thereof. The extruded mixture forms an extrudate having a predetermined cross-sectional shape. The one or more pairs of forming rollers abut to define a passage there between as each forming roller rotates. The passage has a cross-sectional shape corresponding to the predetermined cross-sectional shape. The method can be performed using a machine including an extruder, one or more pairs of forming rollers, and a cutting device.
US11213979B2 Or relating to three dimensional mouldings
The invention relates to a blank for compression moulding a part in a compression mould comprising one or more moulding recesses, said blank comprising a body formed from a first moulding compound comprising a fibrous reinforcement material and a thermo-curable resin material, and a region located on the surface of the body formed from a second moulding compound; said second moulding compound comprising a fibrous reinforcement material and a thermo-curable resin material, and exhibiting increased flow at one or more temperatures between 20° C. and the cured Tg of the first moulding compound compared to the flow of the first moulding compound at the same temperature.
US11213974B2 Method for making polyethylene/graphene composite
A method of forming a polyolefin-carbon nanomaterial composite which contains oriented electrically conductive pathways. The method involves milling a polyolefin with particles of a carbon nanomaterial, molding to form a composite plate, and subjecting the composite plate to an AC voltage. The AC voltage forms oriented electrically conductive pathways by partial dielectric breakdown of the composite. The presence of the oriented electrically conductive pathways gives the polyolefin-carbon nanomaterial electrical and thermal conductivity higher than the polyolefin alone.
US11213973B2 Systems and methods for rapidly producing concrete structures
A three-dimensional printing system that includes a nozzle and means for positioning the nozzle. The nozzle is configured to dispense a concrete mix. The means for positioning the nozzle may include cable and control systems. The cable system includes positioning cables that are connected to the nozzle. The control system includes control modules each connected to a different corresponding one of the positioning cables. Each of the control modules controls a distance that the corresponding positioning cable positions the nozzle from the control module. Alternatively, the means for positioning the nozzle may include first and second flying drones.
US11213968B2 Bread cutting machine with blade guard
A bread cutting machine has a circular blade that is moveable in a guide gap through an extension gap of a machine housing from a waiting position into a cutting space. When the blade is in the waiting position, the guide gap is coverable by a rocker displaceable away from the guide gap simultaneously with the extension of the blade from the waiting position, whereby the guide gap is opened. A cover plate is rigidly fastened to a side surface of the rocker, projects vertically away from the rocker, and covers the extension gap whenever the blade is in the waiting position. By a positive guide, the cover plate is moveable away from the extension gap simultaneously with the movement of the rocker, whereby the extension gap is opened.
US11213967B2 Material compression and portioning
An apparatus includes channel assemblies in a rotatable section, a cutting assembly, a discharge assembly, and a cleanout assembly. The channel assembly holds a bulk instance of compressible material extending through upper and lower channels of a continuous channel. The cutting assembly moves in relation to the channel assembly to isolate the upper and lower channels, severing upper and lower material portions of the bulk instance. The discharge assembly directs gas into the lower channel of a channel assembly to discharge the lower material portion from the lower channel, based on radial alignment of a conduit assembly of the channel assembly with a conduit assembly of the discharge assembly. The cleanout assembly supplies a fluid through the conduit assembly of the channel assembly, based on radially alignment of the conduit assembly of the channel assembly with a conduit assembly of the cleanout assembly.
US11213966B2 Cutting device
A cutting device includes a platen, a mounting portion, a first movement mechanism, a second movement mechanism, a detector, a processor, and a memory. The memory is configured to store computer-readable instructions that, when executed by the processor, instruct the processor to perform processes. The processes include acquiring cutting data, acquiring a contact position output by the detector when the cutting blade comes into contact with the holding member, and controlling the first movement mechanism in accordance with the cutting data to move the mounting portion and the holding member to a cutting start position. The processes include controlling the second movement mechanism, at the cutting start position, to move the mounting portion in the third direction to a cutting position set on the basis of the contact position, and controlling the first movement mechanism in accordance with the acquired cutting data to perform cutting processing.
US11213964B2 Programmable hair trimming system
A hair trimming device arranged to detect positions of the hair trimming device in relation to a client's head and to adjust its trimming length automatically and dynamically according to preprogrammed values at any given point during a hair trimming session.
US11213962B2 Thermal insulative barrier blade cap
A blade cap is provided to shield a user from heat generated by operation of a blade assembly. The blade cap provides an insulative barrier between the blade assembly and the skin of the user. The blade cap may prevent discomfort or burns from the heat generated by the blade assembly. The blade cap includes openings, channels, projections, tabs, and other formations to allow the flow of air through the passageways between the blade cap and the blade.
US11213958B2 Transferring system and method for transferring an object
A transferring system for transferring an object disposed in a storage area includes telescopic units, sucking disc units respectively connected to the telescopic units, and a control unit. The control unit calculates an area related to an object according to an image obtained by an imaging unit, and calculates a value of N based on the area. The value of N is a number of the sucking disc units used for picking up the object and is equal to or greater than one. The control unit determines N positions on the object, controls N telescopic units to move N sucking disc units toward the N positions, and controls the N sucking disc units to adhere respectively to the N positions so as to pick up the object from the storage area.
US11213954B2 Workpiece identification method
Whether or not workpieces are present in a workpiece storage area is determined based on an image acquired by image capturing. When the workpieces are determined to be present, whether or not a crossing part is present in the workpiece storage area is determined based on the image, the crossing part being a part where soft body portions of a plurality of workpieces cross each other in an overlapping manner. When the crossing part is determined to be present, an uppermost soft body portion placed at an uppermost position among the soft body portions crossing each other is determined based on the image. A workpiece including the uppermost soft body portion thus determined is determined as an uppermost workpiece placed at an uppermost position.
US11213952B2 Articulated robot and articulated robot system
An articulated robot includes a lumbar portion including a first joint that rotates about a first axis which is a vertical axis and rotating about the first axis, a second joint connected to the lumbar portion and rotating about a second axis parallel to a horizontal plane, a first arm connected to the second joint and rotating about the second axis, a third joint connected to the first arm and rotating about a third axis parallel to the second axis, and a second arm connected to the third joint and rotating about the third axis. When the first arm extends parallel to the first axis, a clearance through which the second arm rotating about the third axis can pass in a planar area between the second axis and the third axis is provided between the second arm and the first arm and between the second arm and the lumbar portion.
US11213950B2 Proximate robot object detection and avoidance
Systems and methods for proximate robot object detection and avoidance are provided herein which include a receiver in electronic communication with an autonomous robot and configured to receive a broadcast message from a beacon, a processor, and a memory, the memory storing instructions that, when executed by the processor, cause the autonomous robot to detect, based on the received broadcast message, a proximity of the beacon to the autonomous robot, determine, from the received broadcast message, a beacon status, the beacon status indicating whether the beacon is stationary, approaching the autonomous robot, or withdrawing from the autonomous robot, identify, according to the detected proximity and the determined beacon status, a corresponding proximity operation, and control the autonomous robot to stop an ordinary operation and operate according to the identified proximity operation.
US11213946B1 Mitigating reality gap through optimization of simulated hardware parameter(s) of simulated robot
Mitigating the reality gap through optimization of one or more simulated hardware parameters for simulated hardware components of a simulated robot. Implementations generate and store real navigation data instances that are each based on a corresponding episode of locomotion of a real robot. A real navigation data instance can include a sequence of velocity control instances generated to control a real robot during a real episode of locomotion of the real robot, and one or more ground truth values, where each of the ground truth values is a measured value of a corresponding property of the real robot (e.g., pose). The velocity control instances can be applied to a simulated robot, and one or more losses can be generated based on comparing the ground truth value(s) to corresponding simulated value(s) generated from applying the velocity control instances to the simulated robot. The simulated hardware parameters and environmental parameters can be optimized based on the loss(es).
US11213945B2 Robot simulator, robot system and simulation method
A robot simulator includes a storage device that stores model information related to the robot and an obstacle in the vicinity of the robot, and an acquisition device that obtains first input information defining a start position and an end position of operation of the robot. A processing device generates a path for moving the distal end portion of the robot from the start position to the end position while avoiding collisions between the robot and the obstacle based on the first input information and the model information. The processing device also generates image data including an illustration of the obstacle and an index indicating a via-point of the path.
US11213943B2 Moving robot and operating method for the same
A method of operating a robot includes providing position information about a destination; receiving a request for an escort service to the destination in response to the position information; determining whether the escort service is available based on information related to the destination, the information related to the destination including at least one of state information of the destination or time information related to the destination; causing the robot to move and provide guiding to the destination in response to the request when the escort service is available; and notifying that the escort service is not available when the escort service is not available.
US11213942B1 Tool organizer and tool organizer module
In an example, a tool organizer module includes a base including an opening formed at a first side of the base and a feature formed at a second side of the base, to receive a portion of a tool and a magnet disposed in the opening of the base, wherein the feature includes a recession in the second side of the base, and wherein the magnet is disposed to impart, on the second side of the base, a magnetic retention force at least substantially centered about the feature to retain the tool to the second side of the base in the feature for any orientation of the portable tool organizer module and to impart, on the first side of the base, a magnetic retention force to retain the base to a selected surface.
US11213940B2 Dual ended handle for an implement
A dual ended handle such as that used with cleaning implements is provided. The dual ended handle comprises a pole with a first end and a second end, the first end having a first threaded fastener and an implement connecting feature having a tapered cone, the second end having a second threaded fastener and a locking member. A grip having a first end is configured to releasably engage at least one of the first threaded fastener or the implement connecting feature, and a second end configured to releasably engage the second threaded fastener.
US11213938B2 Pressing tool
A pressing tool is described for plastically deforming a workpiece. The pressing tool comprises a piston pump driven by a motor that rotates in operating rotation direction RA and a pressure release valve and a coupling arrangement, which mechanically couples the motor to the pressure relief valve, so that the motor opens the pressure relief valve when operated in a loosening rotation direction RL opposite to the operating rotation direction RA. Also described is a corresponding method of operating a pressing tool.
US11213932B2 Diamond bodies and tools for gripping drill rods
Infiltrated diamond bodies for use in gripping drill rods and other tubulars. One example of such an infiltrated diamond body is a cast diamond roller having a plurality of pads that are separated by channels. Another example of such an infiltrated diamond body is a cast wrench jaw having at least one raised jaw pad.
US11213928B2 Shot processing device
First guide pipes are disposed on both sides of blasting areas, and second guide pipes are disposed on both sides of the blasting area. A wire rod W is inserted through the first guide pipes and the second guide pipes, penetrating in a conveying direction of the wire rod W. The diameter of each of first insertion holes of the first guide pipes and second insertion holes of the second guide pipes is gradually reduced toward the downstream side in the conveying direction. The second guide pipe is installed in a state in which the downstream-side end portion in the conveying direction is inserted into the first insertion hole from the inlet side of the first guide pipe.
US11213927B2 CMP polishing pad conditioner
A method of processing chemical mechanical polishing (CMP) pad conditioners includes providing the CMP pad conditioner including conditioner substrate that is a metal, ceramic or a metal-ceramic material with a plurality of hard conditioner particles with a Vickers hardness greater than 3,000 Kg/mm2 bonded to a top surface of the conditioner substrate, and a slurry including an aqueous medium and a plurality of hard slurry particles having a hardness greater than 3,000 Kg/mm2. The surface of the pad conditioner is polished in a CMP apparatus using a polishing pad. After the polishing each conditioner particle has at least one exposed facet, and the plurality of hard conditioner particles have a maximum average protrusion-to-protrusion flatness (PPF) difference of 20 microns, and a sharpest edge measured by a value of a cutting edge radius (CER) that lies at an edge of the facet for at least 80% of the facets.
US11213925B2 Device for removing burrs from riser of aluminum alloy wheel
Disclosed is a device for automatically removing burrs from a riser of an aluminum alloy wheel. The device is composed of a frame, a clamping gear rack structure, a support plate, a servo motor and the like. When a clamping cylinder drives a first sliding plate to move, clamping wheels are controlled to center and clamp the wheel, and the servo motor controls the rotation of the clamping wheels, so that the wheel may rotate while being clamped. When a distance adjusting cylinder drives a second sliding block to move, a first sliding block and the second sliding block move synchronously under the action of a feed gear rack structure, so that a first deburring tool and a second deburring tool move synchronously to adjust the distance between them according to the diameter of a cap slot.
US11213922B2 Method for producing a piston
A method for producing a piston may include providing a blank of a piston base member with an outer peripheral joining face, an inner peripheral joining face which may be expanded in a direction of a base region of a combustion bowl, and a lower cooling channel portion which may extend between the outer and inner peripheral joining faces, wherein at least one of (i) at least one of the outer and inner peripheral joining faces and (ii) the lower cooling channel portion may be not subsequently processed. The method may then include providing a blank of a piston ring element with an outer annular joining face, an inner annular joining face, and an upper cooling channel portion which may extend between the outer and inner annular joining faces, wherein at least one of (i) at least one of the outer and inner annular joining faces and (ii) the upper cooling channel portion may be not subsequently processed. The method may then include joining the blanks via the outer and inner peripheral joining faces and the outer and inner annular joining faces to form a piston blank in such a manner that, at least in the base region of the combustion bowl, a part-region of the expanded inner peripheral joining face of the blank of the piston base member may remain free. The method may further include subsequently at least partially processing the piston blank to form the piston with the part-region of the expanded inner peripheral joining face being removed.
US11213917B2 Fusion welding of ferrous alloy component parts using low carbon steel band
A method of fusion welding two ferrous alloy component parts, at least one of which is considered unweldable, involves placing a low carbon steel band into a groove defined in part by each of the ferrous alloy component parts and then conveying a concentrated energy source along a welding line that overlaps the low carbon steel band to melt the steel band along with adjacent portions of the ferrous alloy component parts to form a blended alloy weld pool. The blended alloy weld pool solidifies behind the forward movement of the concentrated energy source into a weld joint that fusion welds the ferrous alloy component parts together. The ferrous alloy component parts may include a differential casing and a ring gear. In that regard, a differential casing and ring gear assembly that includes a weld joint is also disclosed.
US11213916B2 Laser machining method
A laser welding apparatus (1) includes a laser welding head (5) configured to irradiate a workpiece (10) with laser light, a welding filler feeding mechanism (6) configured to supply a welding material to a position on which laser welding is performed, and a hollow structural moving mechanism (100) configured to move a welding unit (50) including the laser welding head and the welding filler feeding mechanism. The hollow structural moving mechanism has an insertion portion (3a) through which wire materials (41 and 62) of the laser welding head and the welding filler feeding mechanism are inserted.
US11213915B2 Joining method
Provided is a welding method that can enhance joining quality between an upper plate and a lower plate. One aspect of the present disclosure is a joining method including joining the upper plate to the lower plate that is overlapped with the upper plate by applying energy to a top surface of the upper plate to thereby melt the upper plate and the lower plate together. A joining path designed to apply the energy to the top surface of the upper plate crosses an axis along a joining-travel direction and includes a turn-point. An amount of the energy includes a first energy applied in the vicinity of the turn-point and a second energy amount applied in an area other than the vicinity of the turn-point. The first energy amount is smaller than the second energy amount.
US11213914B2 Laser processing method and method of manufacturing display apparatus
Provided are a laser processing method capable of performing various types of processing while reducing a need to change components and method of manufacturing a display apparatus by using the laser processing method. The laser processing method includes: splitting a laser beam emitted from a laser beam source into a plurality of laser beams by using a laser beam splitter; and transmitting at least two of the plurality of laser beams through a position adjustment equipment that is on paths of the at least two laser beams in order to adjust a distance between the at least two laser beams by using a difference between a refractive index of an element of the position adjustment equipment and a refractive index of a peripheral environment.
US11213909B2 Motor assembly for a push-pull welding torch
Motor assemblies and methods for a push-pull torch are disclosed. An example method includes: rotating a mechanical component about a first axis in a welding torch using a drive motor aligned with the first axis; and feeding a welding wire through the welding torch via a first feed roll and a second feed roll, wherein the first feed roll is operatively coupled with the mechanical component, the first and second feed rolls define a plane through which the welding wire passes, and the plane is generally parallel to and offset from the first axis.
US11213907B2 Methods and systems for selecting welding schedules in a welding-type torch
Systems and methods are provided for selecting welding schedules in welding-type torches. A welding-type torch configured for use during welding-type operations, with the welding-type torch comprising an input device configured for setting a welding-type parameter, such as welding schedules, associated with a welding-type device that is used in conjunction with the welding-type torch during the welding-type operations. The welding-type device may be a welding-type power source. The welding-type torch is connected to the welding-type device via a welding-type connector, with the setting of the welding-type parameter occurring via the welding-type connector and without requiring a change to structure of the welding-type connector. The welding-type parameter is set to one of a plurality of available values, with the input device causes setting the welding-type parameter to a specific value from the plurality of available values only in response to receiving a corresponding specific input associated with that value.
US11213905B2 Wire electrical discharge machining system, wire electrical discharge machining method, and workpiece measurement method
A wire electrical discharge machining system allows a wire electrical discharge machining device and a robot to operate in conjunction with each other with high efficiency. A wire electrical discharge machining system 1 includes wire electrical discharge machining devices 7, 11, and 15, and a robot unit 17 that mounts a workpiece on the wire electrical discharge machining device. The wire electrical discharge machining devices 7, 11, and 15 may each perform either rough machining with supported cores or finishing machining after the cores are removed. Subsequently, core processing may be performed by a corresponding dedicated apparatus. Also, the core processing may be performed by a single common apparatus. The robot unit 17 mounts and collects the workpiece so as to allow these wire electrical discharge machining apparatuses to effectively operate, thereby providing wire electrical discharge machining with improved efficiency for the overall system.
US11213904B1 Apparatuses, systems, and methods for removing and installing a slasher tooth in a saw blade
An apparatus, system, and method for removing and installing slasher teeth in a saw are provided. The apparatus has a first body and a second body having a space formed therebetween, wherein a slasher tooth is positionable within the space. At least one locator pin is connected to at least one of the first and second body, the at least one locator pin contactable to the slasher tooth to locate the first and second body relative to the slasher tooth. At least one engagement device is positioned on one or both of the first and second bodies, the at least one engageable device being actuatable, whereby actuation of the at least one engagement device moves it relative to the first and second bodies and into the space where the at least one engagement device contacts a rivet positioned between the slasher tooth and a saw body.
US11213899B2 Drill, drilling unit, and drilling method
According to one implementation, a drill includes: a drill includes: a body without a back taper; and a cutting edge part integrated with the body. The body has a flow path of a cutting oil inside. The cuffing edge part has a first supply port that supplies the cutting oil toward a workpiece, The body has at least one second supply port that supplies the cutting oil to a clearance formed between a bush for positioning and the body. The bush is used by being inserted in the body.
US11213888B2 Additive manufactured powder processing system
A system for treatment of atomized powder including a fluidized bed operable to treat feedstock alloy powders. A method of treating atomized powder including communicating an inert gas into a fluidized bed; communicating an atomized powder into the fluidized bed; and heating the atomized powder in the fluidized bed, eject the treated powders out of the fluidized bed to quench the powders.
US11213885B2 Castings and manufacture methods
A method includes casting a metallic material (56) in a mold (20) containing a core, the core having a substrate (40, 44) coated with a coating (42). A removing of the metallic material from the mold and decoring leaves a casting having a layer formed by the coating. The coating has a ceramic having a porosity in a zone (50) near the substrate less than a porosity in a zone (52) away from the substrate.
US11213884B1 Stationary vacuum valve
A vacuum valve includes first and second blocks. The first block includes a base portion and a frustoconical guiding portion connected to the base portion and tapering away from the base portion to form a shoulder, and defines a discharging channel extending in the base portion and through the guiding portion, in spatial communication with ambient surroundings, and adapted to permit air to flow therethrough and into the ambient surroundings. The second block has an end surface cooperating with the shoulder to define an opening communicated spatially with the ambient surroundings, and an inner surface connected to the end surface and cooperating with the frustoconical guiding portion to define a spiral fluid channel therebetween. The spiral fluid channel is in spatial communication with the discharging channel and the opening, and is for introducing air into the discharging channel via the opening.
US11213881B2 Component system for producing cores and molds
The object of the invention is a component system for producing a binder for metal casting on the basis of phenolic resins of the benzyl ether type and isocyanates containing non-polar solvents.
US11213879B2 Device and method for producing a component
A device and method for producing a component are provided. The device or method includes steps or units for providing a first component element having a recess in or on a first surface of the first component element, and for positioning a second component element in the region of the recess. The device or method also includes a step or unit for pressing the first component element and the second component element together, and as a result forming a material fit, positive fit and/or non-positive fit between the first and the second component elements at least in the region of the recess. The positioning and the pressing can be carried out or are carried out functionally, in particular, spatially and/or temporally, in terms of equipment, separately from each other.
US11213877B2 Manufacturing method for a finished product of a heat sink composite having heat dissipation function
The invention relates to a manufacturing process for a heat dissipation heat sink composite having heat dissipation function and a manufacturing method for a finished product thereof. It comprises the steps of rolling a first heat conductive material and a substrate to adhere the first heat conductive material to the substrate for fixation; adhering a second heat conductive material to the substrate for combination; and rolling the second heat conductive material and the substrate for firmly combination and fixation to complete the manufacturing of a composite material.
US11213869B2 Solid waste treatment system
A solid waste treatment system includes: a solid-liquid separator module configured to receive mixed solid and liquid waste and separating solid material from the mixed solid and liquid waste; an accumulator and macerator module configured to receive and macerate the solid material from the solid-liquid separator module; a drying module configured to receive and dry the macerated solid material from the accumulator and macerator module; and a combustion module configured to receive and combust the dried macerated solid material from the drying module.
US11213865B2 Cleaning method for workpiece and cleaning apparatus
A cleaning method capable of eliminating cleaning unrequired cleaning points is disclosed. The cleaning method is for a workpiece with foreign matter adhered, and the cleaning method includes: identifying cleaning points of the workpiece with the foreign matter adhered; substituting a true value to a cleaning variable for the identified cleaning points; generating a cleaning liquid jet from a main nozzle; skipping a first cleaning section if the cleaning variable has a false value; and executing the first cleaning section to direct the main nozzle toward the cleaning points if the cleaning variable has a true value.
US11213864B2 Pressure washing system and method
Disclosed herein are various embodiments of a system and method for operating a surface pressure washer with a wand component. The method may include the steps of cleaning a first surface through a first fluid path, where the first fluid path includes a pump, a pressure regulating valve, a diversion block, and a spray gun, while spray nozzles are not discharging fluid to a second surface, actuating a valve connected to the diversion block, thereby reducing the pressure available to the first fluid path and creating a second fluid path, where the second fluid path includes the pump, the pressure regulating valve, the diversion block and the spray nozzles, where the spray nozzles are configured to rotate above the second surface when the second fluid path is open, and cleaning a second surface underneath the pressure washer system through the second fluid path.
US11213863B2 Filling machine and method for filling packages with a fluid product
The invention relates to a filling machine (1, 1′) for filling packages (2) with fluid products with a continuously circulating transport device (14) for transporting the packages (2) through the filling machine (1, 1′), comprising a plurality of cells (15) for receiving the packages (2), wherein a supply device (13) for supplying packages (2) to be filled is assigned to a supply region (16) of the transport device (14), and an output device (27) for outputting the packages (2) is assigned to an output region (28) of the transport device (14), wherein a filling region (17) is provided between the supply region (16) and the output region (28) in the transport direction (14) of the transport device (14), and a return region (29) of the respective transport device (14) is provided between the output region (28) and the supply region (16), and wherein at least one nozzle (38, 38′) for spraying the cells (15) with a cleaning fluid (40) is associated with the return region (29) of the transport device (14). According to the invention, so that the accumulation of impurities and the contamination of the filled product with microorganisms can be better prevented, a spray wall (39) is arranged on the side of the transport device (14) facing away from the at least one nozzle (38, 38′) and opposite the nozzle (38, 38′) in order to catch and discharge cleaning fluid (40) sprayed from the nozzle (38, 38′) and passing the cells (15).
US11213860B2 Automatic magnetic core sorting system based on machine vision
This invention discloses an automatic magnetic core sorting system based on machine vision, which comprises an image acquisition and detection mechanism, a digital conversion module, an image processing module, and a workpiece sorting mechanism. The digital conversion module communicates with the image acquisition and detection mechanism. The image processing module receives the digital signals of images of each workpiece taken from various angles and compares the digital signals with a preset value. Afterwards, the results of comparison are sent to the central control module which judges and controls the operations of the workpiece sorting mechanism according to the results sent from the image processing module. This invention adopts the machine vision-based automatic identification technology to automatically identify color and appearance defects of magnetic sheets on conveyor line. With advantages of real-time and accurate detection with high precision, it greatly improves the efficiency and the degree of automation of production.
US11213859B2 Method for classifying light-emitting semiconductor components and image sensor application having an image sensor and a semiconductor element
The invention relates to a method for classifying a light-emitting semiconductor component (301) for an image sensor application, wherein the semiconductor component (301) is designed as a light source for an image sensor (302), comprising the following steps: providing the light-emitting semiconductor component (301); determining at least one of the following parameters of the light emitted with an emission spectrum by the light-emitting semiconductor component (301) during operation: R=∫qR(λ)·S(λ)dλ·texp, G=∫qG(λ)·S(λ)dλ·texp, B=∫qB(λ)·S(λ)dλ·texp, wherein qR(λ), qG(λ), and qB(λ) are spectral sensitivities of a red, green, and blue color channel of the image sensor (302), S(λ) is the emission spectrum of the light-emitting semiconductor component (301), texp is an exposure time, and λ designates a wavelength; classifying the light-emitting semiconductor component (301) into a class from a group of classes, which are characterized by different value ranges of at least one parameter that depends on at least one of the parameters R, G, and B. The invention further relates to an image sensor application.
US11213858B2 System for processing fruit or vegetable products of the type of blueberries and the like
A system for processing fruit or vegetable products of the type of blueberries and the like, includes a first unit, in its turn having in series at least one loading station, at least one pre-sizing station, at least one pre-selection station and at least one first alignment station. The system further includes a second unit, in its turn having in series at least one second alignment station, at least one optical sizing station and at least one distribution station. Each of the first unit and the second unit has dimensions and space occupation compatible with its accommodation and transport in a single container.
US11213856B2 Method and apparatuses for screening
Methods and apparatuses for screening are provided. Embodiments include a screen basket apparatus for screening material, comprising a grid frame having a plurality of openings arranged in a lattice and a plurality of screening cartridge assemblies affixed to the grid frame to cover the respective openings of the grid frame. The screening cartridge assembly includes a case and a screen assembly fitted into the case, and may be affixed to a set of transversal member of the grid frame. The case may be an injection molded thermoplastic polyurethane or a thermoset polymer. The screening elements together form a generally continuous screening surface across an exterior portion of the grid frame.
US11213854B2 Method of forming multilayer coating film
A method of forming a multilayer coating film with excellent flip-flop properties and smoothness and allowing formation of a high-design multilayer coating film. In a method of forming a multilayer coating film comprising: a low-brightness intercoating film; a first base coating film; a second base coating film formed on an object to be coated; and a clear coating film formed on the second base coating film; the first base coating film is obtained by applying a first aqueous base coating material, the second base coating film is obtained by applying a second aqueous base coating material containing a brightness pigment, the clear coating film, with specific compositions and properties, is formed on a low-brightness intercoating film by a wet-on-wet method and the multilayer coating film is heat cured to form a cured multilayer coating film.
US11213853B2 Selective deposition of metals, metal oxides, and dielectrics
Methods are provided for selectively depositing a material on a first surface of a substrate relative to a second, different surface of the substrate. The selectively deposited material can be, for example, a metal, metal oxide, or dielectric material.
US11213852B2 Photocatalyst layer, photocatalyst, and method for manufacturing photocatalyst
Provided is a photocatalyst layer that improves the photocatalytic performance while suppressing detachment of photocatalyst particles. The photocatalyst layer has a front surface and a rear surface on the opposite side of the front surface. The photocatalyst layer includes photocatalyst particles and a binder. The photocatalyst layer has a first region containing the photocatalyst particles and a second region containing the binder and not containing the photocatalyst particles. The photocatalyst particles include tungsten oxide particles. The photocatalyst particles have contact points being in contact with the rear surface. The ratio of the thickness of the second region to the number-average secondary particle diameter of the photocatalyst particles is 0.20 or more and 0.80 or less.
US11213851B2 High speed granule delivery system and method
A high speed granule delivery system and method is disclosed for dispensing granules in intermittent patterns onto a moving asphalt coated strip in the manufacture of roofing shingles. The system includes a granule hopper and a rotationally indexable pocket wheel in the bottom of the hopper. A series of pockets are formed in the circumference of the wheel and the pockets are separated by raised lands. A seal on the bottom of the hopper seals against the raised lands as the wheel is indexed. In use, the pockets of the pocket wheel drive through and are filled with granules in the bottom of the hopper. As each pocket is indexed beyond the seal, it is exposed to the moving asphalt coated strip below and its granules fall onto the strip to be embedded in the hot tacky asphalt. The speed at which the wheel is indexed is coordinated with the speed of the asphalt coated strip so that granules and strip are moving at about the same forward speed or at a preselected ratio of speeds when the granules fall onto the strip. Well defined patterns of granules are possible at high production rates.
US11213847B1 Cover for spray a gun
An apparatus is disclosed for covering an airless spray gun for the purpose of protecting the gun while preventing unintended triggering. Protecting the gun prolongs the life of the tool while preventing unintended triggering helps prevent injection injuries. In one embodiment a semi-rigid elastomeric form encloses the top, front, bottom and at least a portion of the sides of an airless spray gun, or air assisted spray gun, while a flexible elastomeric material covers a significant portion of the sides of the tool.
US11213840B2 Mixer design for a plural component system
A mixer for a plural component spray gun is presented. The mixer has a mixer body comprising a mixing chamber with an outlet. The mixer also has a first fluid component inlet, coupled to a first fluid conduit, configured to introduce a first fluid component into the mixing chamber. The mixer also has a second fluid component inlet, coupled to a second fluid conduit, configured to introduce a second fluid component into the mixing chamber. The first and second fluid component inlets are offset with respect to a centerline of the mixing chamber and positioned such that a first fluid flow from the first inlet is directed toward the outlet, and a second fluid flow from the second inlet is directed toward the outlet.
US11213836B2 Nutating sprinkler head
A sprinkler head for irrigation having a sprinkler body. The sprinkler body surrounds a fluid delivery tube. The sprinkler body includes an upper plate and a lower plate. A and exits out the fluid nozzle. A fluid distribution cage is positioned on the sprinkler body and around the fluid delivery tube. The fluid distribution cage has one or more arms connecting an upper plate and a lower plate. The lower plate is configured to direct fluid sprayed onto it from the fluid delivery tube. When fluid is sprayed on the lower plate the upper plate begins to nutate around the fluid delivery tube between the upper sprinkler body plate and lower sprinkler body plate. The upper and lower sprinkler body plates have races configured for receiving one or more resilient cushions positioned on the upper plate of the fluid distribution cage. The upper cage plate or the lower sprinkler body plate has one or more projections positioned such that the fluid distribution cage hangs at an angle to facilitate initiation of nutation of the fluid distribution cage.
US11213832B2 Surface cleaning apparatus, cyclonic air treatment member and surface cleaning apparatus including the same
A surface cleaning apparatus comprises an air treatment member having an air treatment chamber. A moveable member is positioned in the air treatment chamber. A driving assembly is drivingly connected to the moveable member wherein the driving assembly is operable between a stored position is which the surface cleaning apparatus is operable to clean a surface and a cleaned position in which the moveable member has been translated through at least a portion of the chamber, wherein, in the stored position, a portion of the driving assembly is longitudinally spaced from the first and second axially spaced apart ends of the air treatment chamber.
US11213831B2 Centrifugal separator having an outlet channel of varying height
A centrifugal separator having a device for the transformation of kinetic energy of a liquid rotating in a discharge chamber around a rotational axis to pressure energy includes a discharge element for the discharge of liquid out of the discharge chamber, which discharge element has a radially outer part shaped as a body of revolution about the rotational axis and is arranged to be located in a rotating liquid body in the discharge chamber, and at least one outlet channel formed in the discharge element and having an inlet opening located in a surface of the body of revolution and elongated in the liquid flow direction, the inlet opening connecting to the interior of an outlet tube via the outlet channel. The outlet channel has a defined axial height and a defined width which vary along their extension from the inlet opening to the connection to the outlet tube in such a way that a defined aspect ratio h/w decreases along at least a part of the extension of the outlet channel. A defined aspect ratio h/w is larger than 1 in an outer first part of the outlet channel and decreases to smaller than 1 in an inner second part of the outlet channel and the height decreases inwardly along the length of the outlet channel.
US11213829B2 High slurry density hydraulic disassociation system
A comminution system for heterogeneous materials includes pumps, a source of liquid in fluid communication with the pumps, a source of heterogeneous material, a mixer to combine the heterogeneous material and the liquid, and nozzles in fluid communication with the pumps, respectively. The pumps are in straight-line alignment with the nozzles. The nozzles receiving the heterogeneous material combined with the liquid direct the combined slurry to an impact zone where the fractions of the heterogeneous material are disassociated.
US11213828B2 Device and method for comminuting bulk material grains
A device for comminuting bulk material grains (K) having a first element, designed as a rotor having a cylindrical circumferential surface with a first surface (31) and a first receiving portion (41), and a second element designed as a shear strip (51) having a second surface (61) and a second receiving portion (71), and a supply unit. The first and the second surfaces (31, 61) lie parallel to and face one another. The first and second elements are relatively movable between first and second positions (P1, P2) in a plane of the first and the second surfaces (31, 61). In the first position (P1), the first and second receiving portion (41, 71) communicate with one another, via a passage (9) forming a receptacle, in which the bulk material grain (K) can be positioned, and, upon moving to the second position (P2), a cross section of the passage (9) is narrowed.
US11213823B2 Microfluidic in situ labelling on stable interfaces
A method of trapping constituents of interest in a fluid sample flowing through a microfluidic channel by vibrating an interface of the fluid sample and a gas occupying a lateral channel adjacent the microfluidic channel is described. A marker is flowed into the microfluidic channel such that the marker bonds with constituents of interest. The constituents of interest bonded to the marker can help identification of the constituents of interest.
US11213821B2 Microfluidic device and manufacturing method therefor
The present invention relates to a microfluidic device and a manufacturing method therefore and, more particularly, to a microfluidic device comprising: a first substrate layer; a second substrate layer formed on at least one surface of the first substrate layer; and a plurality of transducers formed on the surface of the first substrate layer and embedded in the second substrate layer, wherein the transducer comprises a conductive microfluidic channel. The present invention can provide an elastic wave substrate microfluidic device capable of controlling an elastic wave according to a property of a microparticle and capable of being manufactured without expensive equipment and complicated process procedures.
US11213820B2 Microfluidic chip, device and method for chemiluminescence immunoassay
The present disclosure provides a microfluidic chip, a device and a method for chemiluminescence immunoassay. The microfluidic chip includes a base plate, as well as a first liquid inlet channel, a second liquid inlet channel, a third liquid inlet channel, an immune reaction cell, and a luminescent reaction cell formed on a first surface of the base plate. An outlet end of the immune reaction cell is in communication with a liquid inlet end of the luminescent reaction cell, and a primer is disposed in the immune reaction cell for immobilizing an antigen-antibody complex generated in the immune reaction cell.
US11213818B2 Systems and devices for microfluidic instrumentation
Various embodiments herein disclose a device, comprising one or more fluid interfacing components and a cartridge holder, wherein the one or more fluid interfacing components are fixed while the cartridge holder moves along a linear guide. Also disclosed herein are methods of using the device to analyze a sample containing particles, and methods of diagnosing a disease in a subject by using the device.
US11213817B2 Digital microfluidic dilution apparatus, systems, and related methods
Example methods, apparatus, systems for diluting samples are disclosed. An example method includes depositing a first fluid droplet on a first electrode of a plurality of electrodes. The first electrode has a first area. The first fluid droplet has a first volume associated with the first area. The example method includes depositing a second fluid droplet on a second electrode of the plurality of electrodes. The second electrode has a second area. The second fluid droplet has a second volume associated with the second area. The second volume is different than the first volume. The example method includes forming a combined droplet by selectively activating at least one of the first electrode or the second electrode to cause one of the first fluid droplet or the second fluid droplet to merge with the other of the first fluid droplet or the second fluid droplet.
US11213814B2 Detection apparatus for detecting analyte in a liquid sample and method thereof
The present invention discloses a detection apparatus, comprising a base layer, wherein the base layer comprises a groove for containing a testing element and a sample chamber for collecting a fluid sample. The detection apparatus can achieve fast, efficient and accurate detection of analytes in liquid samples, make operators to perform testing conveniently and freely, without causing incorrect results. In some preferred modes, the sample chamber comprises a liquid channel.
US11213812B2 Hybrid sorbent
Hybrid sorbent on the base of anion-exchange polymeric matrix with HFO for selective sorption of arsenic characterized in that, HFO exists in matrix as particles, which at most are amorphous ferrihydrite, fraction of which is not less than 80%, preferably more than 90% from total mass of HFO.The object of the invention and the technical result achieved with the use of the invention is to develop new hybrid sorbent with HFO with increased sorption kinetics of two arsenic forms As(III) and As(V) simultaneously.
US11213811B2 Preparation method for olefin epoxidation catalyst and applications thereof
Disclosed in the present invention are a preparation method for an olefin epoxidation catalyst and applications thereof. The method comprises: loading an auxiliary metal salt onto a silica gel carrier, and carrying out a drying treatment to the silica gel carrier; loading a titanium salt (preferably TiCl4) onto the silica gel carrier by a chemical vapor deposition method; calcining to obtain a silica gel on which the auxiliary metal oxide and Ti species are loaded; obtaining an catalyst precursor (Ti-MeO—SiO2 composite oxide) by water vapor washing; loading alkyl silicate (preferably tetraethyl orthosilicate) onto the surface of the catalyst precursor by a chemical vapor deposition method and calcining the catalyst precursor to obtain a Ti-MeO—SiO2 composite oxide with the surface coated with a SiO2 layer; and carrying out a silylanization treatment to obtain the catalyst. The catalyst can be applied to a chemical process of propylene epoxidation to prepare propylene oxide, and has an average selectivity to PO up to 96.7%, the method of the present invention and the applications thereof have industrial application prospects.
US11213809B2 Germanosilicate compositions of CIT-14 topology and methods of preparing and using the same
The present disclosure is directed to novel germanosilicate compositions and methods of producing and using the same. In particular, this disclosure describes new germanosilicates of CIT-14 topology. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.
US11213805B2 Catalyst for the conversion of natural or associated gas into synthesis gas in an autothermal reforming process and method for preparing the same
A catalyst in a calcined state has a specific surface area of 20-50 m2/g of catalyst, and a specific surface area of nickel metal after reduction of the catalyst of 8 to 11 m2/g, wherein the average particle size of nickel metal is 3-8 nm, the dispersion of the particles is 10-16%, and the content of nickel is 5-15 wt. % based on the weight of calcined catalyst. A support has a specific surface area of 40-120 m2/g with a pore volume of the support of 0.2-0.4 cm3/g, wherein the support is selected from a mixture of zirconium oxide and cerium oxide or magnesium oxide, cerium oxide and the ballast being zirconium oxide. The catalyst further contains a promoter selected from the group consisting of palladium and ruthenium, in an amount of from 0.01 to 0.5 wt. %. The catalyst is prepared by co-precipitation with ammonium hydroxide from a solution containing nickel, cerium and zirconium precursors and distilled water or from a solution containing nickel, cerium, zirconium, and magnesium precursors and distilled water, and having a pH of 8.0-9.0. The process is carried out under agitation at a temperature of 40-45° C. for 1-2 hours, followed by filtration, drying at a temperature of 100-110° C. for 6-8 hours, and calcining at a temperature of 400-650° C. for 4-6 hours. The invention provides a high average conversion of natural/associated gas of at least 90% in an autothermal reforming reaction of natural or associated gas, and a high synthesis gas output of at least 7000 m3/m3cat·h.
US11213794B2 CO rich synthesis gas production
The invention relates to a chemical reactor and reformer tubes for reforming a first feed stream comprising a hydrocarbon gas and steam. The chemical reactor comprises a shell with a heat source and one or more reformer tubes. The reformer tube is arranged to house catalyst material and is arranged to being heated by the heat source. The reformer tube comprises a first inlet for feeding said first feed stream into a first reforming reaction zone of the reformer tube, and a feed conduct arranged to allow a second feed stream into a second reforming reaction zone of the reformer tube. The second reforming reaction zone is positioned downstream of the first reforming reaction zone. The feed conduct is configured so that the second feed stream is only in contact with catalyst material in the second reforming reaction zone. The invention also relates to a process of producing CO rich synthesis gas at low S/C conditions.
US11213788B2 Method of flue gas denitrification
A method for flue gas denotation includes the step of, in the presence of ammonia, enabling flue gas in a denitration reactor to pass through a plurality of catalyst beds from the bottom to the top to participate in a denitration reaction. Each catalyst bed contains a catalyst support component and a granular denitration catalyst stacked on the catalyst support component, and, in every single catalyst bed, the granular denitration catalyst moves along a same direction on the catalyst support component. Between every two adjacent catalyst beds, the granular denitration catalyst falls from the tail of a previous catalyst support component to the head of a next catalyst support component, making the granular denitration catalyst travel along the catalyst support components reciprocatively.
US11213787B2 Method and system for controlling mercury emissions from coal-fired thermal processes
The present disclosure is directed to the use of elemental or speciated iodine and bromine to control total mercury emissions.
US11213786B2 Methods and systems for managing gas purification
A method for extending useful life of a sorbent for purifying a gas by sorption of an impurity is provided. The method generating a electrical discharge within the gas to obtain a spectral emission representative of a concentration of the impurity. The method also includes monitoring the concentration of the impurity according to the spectral emission. The method also includes lowering the concentration of the impurity by conversion of at least a portion of the impurity into a secondary impurity having a greater affinity to the sorbent than the impurity. The method also includes comparing the concentration of the impurity to a polluting concentration and managing the sorption of the gas onto the sorbent according to the comparison.
US11213781B2 Pattern-plugged honeycomb bodies, particulate filters, and extrusion dies therefor
A honeycomb body having intersecting porous walls which includes first through fourth cells, wherein the cells extend from inlet to outlet face and are plugged to define a repeating structural unit with three inlets and one outlet channel. Repeating structural unit includes a first channel including length L1, width W2, and area A1, a second channel including length L2, the width W2, and area A2, a third channel including the length L1, width W1, and area A3, and a fourth channel including the length L2, the width W1, and A4, wherein the first through third channels are inlets and the fourth channel is a rectangular outlet and at least one of W1≥W2 and L1≠L2, i.e. W1≥W2, or L1≠L2, or W1≥W2 and L1≠L2. Repeating structural unit has a quadrilateral outer perimeter. Particulate filters including the honeycomb body, honeycomb extrusion dies, and methods of manufacturing the honeycomb body are provided.
US11213780B2 Air filter with passivated filter life indicator
An air filter including a visually uniform filter life indicator (30), the air filter (1) comprising: a conformable, unframed air filter media (10) that is installable on at least a portion of an upstream face (11) of a filter-support layer of an air-handling system, wherein the conformable, unframed air filter media comprises at least one passivated area (20) that provides a visually uniform filter life indicator of the air filter. Filter life indicators are used in order that aspects of the filtration performance of an air filter can be monitored.
US11213779B2 Low-gravity water capture device
An apparatus to separate water droplets from an air stream includes an elongated tube having a first end and a second end. The elongated tube includes an opening at a first end of the elongated tube, the opening may be positioned to accept the air stream. A reservoir is positioned at a second end of the elongated tube. A helix structure is positioned within the elongated tube. The helix structure includes an upper surface, a lower surface arranged opposite the upper surface, an outer edge, and a variable pitch along a length of the elongated tube. The variable pitch may provide a variable interior angle between an inner wall of the elongated tube and the upper surface of the helix structure.
US11213777B2 Titanium oxide-comprising fibrous filter material
A filter may remove PM2.5 and/or other airborne pollutants, which filter has fibers of an average diameter of no more than 500 nm, the fibers of at least 90 wt. % polyacrylonitrile, relative to all fibers in the filter; and a catalyst of at least 90 wt. % TiO2, relative to all catalytic metals in the filter, dispersed onto the fibers. The fibers need not be charged. The TiO2 may be condensed or precipitated onto the fibers out of a liquid containing the TiO2 and the fibers by simple methods. The catalyst may be activated by UV irradiation to decompose particulate matter having an average particle size of 2.5 μm or less, i.e., PM2.5, and/or other airborne pollutants from air. Such filters may be implemented around areas of vehicle traffic, e.g., as elements of traffic lights, and may be used to controllably purify polluted air.
US11213776B2 Leukocyte removal filter material and leukocyte removal method
There is disclosed a leukocyte removal filter material comprising a nonwoven fabric having polybutylene terephthalate fiber. The average fiber diameter of the nonwoven fabric is 0.9 to 1.5 μm, the formation index corresponding to a thickness of 0.3 mm of the nonwoven fabric is 15 to 70, and when the average fiber diameter of the nonwoven fabric is X and the specific surface area of the nonwoven fabric is Y, X and Y satisfy the following relational expression (1): Y≥−0.65×X+1.75  (1).
US11213775B2 Fuel filter cartridges with automated air-bleeding internal features
A filter assembly includes a housing having an outer cavity and an inner cavity, and a gasket disposed within the housing. The gasket includes an inner surface, an outer surface, and a vent passage. The gasket forms a first seal with a central tube at the inner surface. The central tube extends into the inner cavity and includes an opening. A filter element is positioned within the housing and includes a filter media configured to filter a fluid and an endcap including an annular tab portion that forms a second seal with the outer surface of the gasket when the filter element is positioned in an operating position within the housing. The vent passage circumvents the first seal and the second seal, allowing air to flow from the inner cavity of the housing to the opening in the central tube.
US11213765B2 Method for recovering transition metal tetrahalide and hydrocarbons from a waste stream
The present invention provides a process for recovering transition metal tetrahalides from a waste stream coming from a catalyst manufacturing process by (a) establishing a mixed stream comprising transition metal tetrahalide and transition metal alkoxyhalides; (b) forming a falling liquid film from the mixed stream of step (a) at a temperature of from 25 to 85° C. and an absolute pressure of from 0.05 to 0.6 bar; and (c) establishing from the film of step (b) a first vapour stream containing from 90 to 100% of recoverable components and a second liquid stream containing about 10 to 80% of titanium haloalkoxides.
US11213761B2 Comforting device
A comforting device for soothing and comforting a user includes a shell, which defines an interior space. The shell is pliable and can be grasped by the user. A filler, which is resiliently compressible, is positioned in and substantially occupies the interior space. An audio module, which is positioned in the interior space, selectively emits a first sound, which mimics a heartbeat, and a second sound, which mimics a respiratory sound, such as breath sounds and snoring. The audio module broadcasts the first sound and the second sound to comfort the user.
US11213760B2 Managing game sessions in a social network system
This disclosure is directed to enabling access to a game instance through a social network system. A client-side player component facilitates communication between a game instance on the client device and a backend server of a social networking system. The communication information can be stored in or retrieved from a social graph of the social networking system. The game instance can be initialized from a social platform of the social networking system, and the game can be played without leaving a social network application.
US11213758B2 Methods, systems, and devices for identifying a portion of video content from a video game for a player or spectator
Aspects of the subject disclosure may include, for example, obtaining portions of video content from a video game from video game server(s) associated with a video game provider, selecting a first portion of video content from the portions of the video content, and providing the first portion to device(s) associated with viewer(s). Each device presents the first portion of the video content. Further embodiments include obtaining popularity information from the device(s) according to feedback based on presenting the first portion of the video content to the device(s), determining that the popularity information satisfies a popularity threshold associated with the video content, determining a subject matter corresponding to the first portion of the video content, and identifying a second portion of the video content from the video game to be recorded according to the subject matter. Other embodiments are disclosed.
US11213752B2 System and method for synchronizing and predicting game data from game video and audio data
Systems and methods for capturing and utilizing multimedia-based analytics to generate predictions about game-play in computer-based games and contests. In an embodiment, a video feed analyzes one or more video feeds frame by frame to determine one or more features within each video frame. Each feature may be collected in a central data collector and converted to one or more metrics about each collected parameter or feature. These metrics may be used to analyze and predict various aspects of the underlying game or contest, such as probability of winning by one side or the other. Further, the predictive data and analytical data may be displayed on a display separate from actual gameplay or may be overlaid upon the game play video feed. In this manner, the overlay video may be synchronized with the original video feed to present predictive data in conjunction with the video data used to influence the predictive data at the time.
US11213749B2 Networked memory enhancement game using customizable images
The present invention is a networked, customizable game for exercising and improving memory and recall that can be played by from one to multiple players. The game is easily played by young and old players alike. The game can be customized by creators as well as sponsored by commercial ventures. The game is dimensioned and configured so as to create and to play a highly individualized, memory-exercising protocol via mobile “smart” phones and over the Internet. The game can also be configured to limit the players to those potential players within pre-selected geographic distance from the player initiating the game.
US11213747B2 Systems of stacking interlocking blocks
A system of stacking interlocking blocks can be configured into a series of states in order to capture and display both physical and virtual events or content. In some examples, the system includes the stacking interlocking blocks, a grid base having the stacking interlocking blocks stacked on top of the grid base in a physical configuration, and a user system. Each stacking interlocking block includes a block circuit. The grid base includes an embedded computing system configured, by virtue of communicating with each of the block circuits, to determine a position of each stacking interlocking block with respect to the grid base and in some cases both the grid base and the other blocks which have been detected by the grid base.
US11213745B1 User interface rendering and post processing during video game streaming
Systems and methods for conservation of bandwidth and improved user experience via enhanced streaming of video games. An example method includes receiving a request to remotely play a video game, the video game being executed by the system and streamed to a user device for presentation. The video game is executed, and rendered image frames are generated. Geometry data associated with the rendered image frames is generated, with the geometry data representing locations of geometric elements that form geometry utilized, by the video game, to generate the rendered image frames. The rendered image frames are encoded into a gameplay stream. A first stream comprising the encoded gameplay stream and a second stream comprising the geometry data are provided to the user device. The user device is configured to perform post-processing effects on the rendered image frames encoded in the gameplay stream prior to display on the user device.
US11213743B2 Method, system and electronic device for achieving remote control of computer game by game controller
The present disclosure provides a method for remote control of computer game by a gamepad, including: remotely accessing, by the client-side, the virtual cloud desktop provided by the server-side, and sending message to the server-side when detecting gamepads; creating or enabling by the virtual cloud desktop server-side, a corresponding number of virtual game devices; capturing, by the client-side, the operation instruction data of the gamepads, and sending the operation instruction data to the server-side; causing each virtual game device to output a KeyCode value corresponding to each operation instruction data by the server-side, such that the virtual cloud desktop server runs the computer game according to each KeyCode value and the relative movement value of the joystick; sending the data of the running results of the computer game on the virtual cloud desktop to the client-side for display.
US11213742B2 Gaming machine controller and method of use
An application enabling a player to utilize a portable computing device, such as a Smartphone, to function as a game controller for a gaming machine. The user would receive and return an associating link code to initiate a communication link between the gaming machine and the portable computing device by way of tapping, manually entering the code, or scanning an image of the code. The portable computing device enables manual user input or use of motion controllers for controlling skill based games in a casino environment. The application can receive a configuration from the gaming machine to replicate or mimic the controls and the gaming images, thus enabling the player to play the game at a short distance from the machine. The gaming machine can suspend play or terminate play when the portable computing device becomes distant or disconnected from the gaming machine.
US11213741B2 Board game
A method of playing a board game includes a game board arranged as a grid. The board is set up before play where certain playing squares include first or second indicia such that respective numbered tiles with matching indicia may be randomly placed on the certain playing squares. Players may then perform a series turns placing tiles having a third indicia on the board in a single straight line using at least one of the numbered tiles already placed on the board. The tiles must create one or more linear sequences wherein the sum of the numbered tiles within each linear sequence equals a predetermined value. Points are awarded to the player based at least in part on the number of linear sequences created during the turn. The winner may be the player with the highest total awarded points at the end of the game. Other aspects are also provided.
US11213737B2 Figure skating boot with monocoque structure
A figure skating boot has a monocoque structure formed of monocoque material including a sole portion to receive the foot thereon, inner and outer side wall portions, a heel cup portion about the heel, two ankle portions extending over the ankles, and front and rear mounting surfaces below the sole portion for connection to front and rear ends of a mounting frame, for example the mounting frame of a skate blade. A heel member is formed separately from the boot and is supported by the monocoque material to extend downwardly from the heel end of the sole portion so that the rear mounting surface is at the bottom of the heel member. Each ankle portion is joined to the respective side wall portion by a relief junction enabling the ankle portions of the monocoque structure to be flexed relative to the side wall portions of the monocoque structure.
US11213736B2 System and methods for designing and manufacturing a bespoke protective sports helmet
A bespoke protective sports equipment to be worn by a player engaged in a sporting activity is provided. The bespoke sports equipment system includes methods for acquiring, storing and processing a player's unique data, namely the anatomical features of the body part against which the bespoke equipment is worn. The systems also includes methods of using the player's unique data to manufacture the bespoke protective equipment with a custom formed internal padding assembly that substantially corresponds to the player's unique data. The system and method allows for the design and manufacture of bespoke protective sports equipment that is purposely designed and manufactured to match the anatomical specifications of the player's body part.
US11213733B1 Surface interactions in a virtual reality (VR) environment
A virtual reality (VR) system comprising a head-mounted display (HMD) and handheld controller set is enhanced to provide a more realistic end user VR experience, e.g., for generalized surface interactions in the VR environment. The techniques herein leverage controller-less calibration with any type of surface, followed by surface interactions in the VR environment. An example use case is an interactive fitness training session.
US11213731B1 Adjustable target system
An adjustable target system for use on a goal having a first post, a second post, and a crossbar. The adjustable target system includes a frame and a bracket configured and arranged for adjustably attaching the frame to one of the first post, second post, and crossbar. The bracket is configured and arranged for removably attaching to one of the first post, second post and crossbar without the use of tools.
US11213729B2 Golf club head
A golf club head includes a cover member, and a club head main body comprising a crown portion, a sole portion and a back-side outer rim portion. The club head main body is made of a first material. The club head main body is provided with a crown opening and a cutout. The cutout is made up of a first opening on the crown portion side and a second opening on the sole portion side, and these opening are connected with each other in the back-side outer rim portion. The width of the cutout and the contour length of the back-side outer rim portion in the top view of the club head are relative with each other. The cover member is made of a second material having a specific gravity lower than the first material. The crown cover closes the crown opening and the first opening. The sole cover closes the second opening.
US11213722B2 Swimming speedometer system with near-eye display
An apparatus and method for measuring a swimmer's speed and conveying the speed to the swimmer in real time includes a plurality of ultrasonic beacons each having a transducer configured to emit ultrasonic signals in a pool or other body of water within which the swimmer is swimming. A wearable, waterproof, ultrasonic receiver worn by the swimmer, receives the ultrasonic signals and generates corresponding signal data. The receiver's microcontroller captures and uses the signal data to calculate the swimmer's position and speed in real time, and conveys this information to a wearable, waterproof, user interface device worn by the swimmer, the user interface device including a near-eye display disposed on the swimmer's goggles.
US11213719B1 System and method of using two exercise machines
A system and method of using two exercise machines for performing a wide range of exercise movements that utilize both of the exercise machines in concert. The system and method of using two exercise machines generally includes first exercise machine and a second exercise machine which are used in concert to perform a wide range of exercise movements. The first exercise machine may include a track, a carriage movably connected to the track, and an end platform. The second exercise machine may include its own separate track, a carriage movably connected to the track, and an end platform. The exercise machines may be positioned side-to-side in parallel orientation such that an exerciser may perform various exercise moves by positioning different limbs on the respective carriages, end platforms, and/or tracks of the exercise machines, in addition to the surface underlying the exercise machines.
US11213714B2 Weightlifting device
The invention relates to a weightlifting device comprising a longitudinally extending bar, the bar comprising at least one weight bearing section adapted for accommodating one or more free weights comprising an opening adapted for surrounding the weight bearings section. The weight bearing section comprises an end stop for the one or more free weights at a first end of the weight bearing section, a recess at or adjacent to a second opposite end of the weight bearing section and a free weight locking member for locking the free weights and for preventing the free weights from unintentionally falling off from the second end. The free weight locking member is movable in a longitudinal direction of the weight bearing section between the recess and at least one free weight locking position located between the recess and the end stop. The free weight locking member is further movable in a second direction at the recess between an immersed position and an elevated position, the immersed position being a position where the free weight locking member is completely, or at least mainly, immersed into the recess, and the elevated position being a position where the free weight locking member is elevated with respect to the immersed position and extends at least partly outside the recess.
US11213710B2 Ergonomic yoga block and method of use
A system and method for a yoga block having molding on the outer surfaces of the block to fit the hand of a user and support the hand in a neutral wrist position so as to prevent pain and discomfort in the wrist, in particular, when the user is performing yoga exercises.
US11213705B2 Fall-protection apparatus with protective shroud and with sleeve assembly
A fall-protection apparatus with a movable protective shroud and with a sleeve assembly, the sleeve assembly including an informational sheet that is compactable and extendable.
US11213702B1 Hygiene mask with seal forming structure
A mask for use at an operating pressure substantially equal to atmospheric pressure includes a body with a three-dimensional shaped chamber that is configured to receive a user's mouth and nares and operate at the operating pressure. The mask also includes a seal forming structure with a nose seal portion that extends around at least a portion of the user's nares on an inferior side of the user's nose inferior to the user's nasal ridge, and a mouth seal portion that forms a seal at least partially around the user's mouth and between the user's chin and lip inferior. The nose seal portion is directly connected to the mouth seal portion. The mask also includes a positioning and stabilising structure to provide a force to hold the seal forming structure in position against the user.
US11213701B2 Neuroprotective quinoline sulfonamides
Disclosed herein are methods and compositions comprising compounds capable of activating and increasing protein SUMOylation. Disclosed herein are methods and compositions comprising compounds capable of showing neuroprotective and cytoprotective effects when administered to injured cells. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, chronic traumatic encepholopathy, traumatic brain injury, or stroke.
US11213700B2 Brachytherapy afterloader device
A brachytherapy afterloader device, comprises at least one transmit wire that is suitable for being inserted and driven in an advance or retract motion in an external first delivery channel and for delivering drive energy to a test field source, which is arranged at a distal end region of the transmit wire, for generating a magnetic test field; at least one receive wire that is suitable for being inserted and driven in an advance or retract motion in an external second delivery channel for a measurement of the magnetic test field, the receive wire having a transducer that is configured to detect magnetic-field changes in the magnetic test field; and a wire driving unit which is configured to controllably advance or retract the transmit wire and the receive wire in response to a corresponding test drive control signal.
US11213697B2 Adaptive aperture
An example particle therapy system includes a particle accelerator to output a particle beam having a spot size; a scanning system for the particle accelerator to scan the particle beam in two dimensions across at least part of a treatment area of an irradiation target; and an adaptive aperture between the scanning system and the irradiation target. The adaptive aperture includes structures that are movable relative to the irradiation target to approximate a shape to trim part of the treatment area. The part of the treatment area has a size that is based on an area of the spot size.
US11213696B2 Method, system and computer program product for ion radioitherapy
A method of performing dose calculations for ion radiotherapy compensating for tissue in which the density within a voxel may be inhomogeneous by approximating a portion of the voxel as an air cavity. For each dose voxel, the voxel is inscribed in a three-dimensional grid comprising a number of cells and the propagation of ions through the voxel is calculated based on the cell pattern in the at least one cell overlapping the voxel. Preferably, the voxel is inscribed in the three-dimensional grid in such a way that it overlaps at least one cell fully. Each cell comprises a first portion representing a first density corresponding to a density of a tissue and a second portion representing a second density corresponding to the density of air, the first and second portions forming a cell pattern.
US11213695B2 Illuminated bandage and method for disinfecting a wound
An illuminated bandage and method of disinfecting a wound. The illuminated bandage includes a power source, a light source coupled to the power source to generate light and a patch. The patch includes a supporting medium and at least one light diffusing element in the supporting medium and optically coupled to the light source. The light diffusing element outputs light to promote a photochemical reaction to disinfect a wound surface proximate thereto.
US11213693B2 Light source for eye therapy and light emitting device having the same
A light source for eye therapy configured to emit light having a wavelength range from about 380 nm to about 780 nm, and has a spectrum area that overlaps at least about 55% of an area of a normalized solar spectrum, in which a peak wavelength of light has a deviation equal to or less than about 0.14 from the normalized solar spectrum in a wavelength range from about 380 nm to about 490 nm.
US11213692B2 Body-conforming, micro-coil, web apparatus and method
A PEMF web using immersive, flux-guided, micro-coils to direct intense, deeply penetrating, magnetic flux into a subject from each micro-coil capable of pointing in an arbitrary direction. Micro-coils are spooled around iron cores, insulated properly, and soldered to connecting wires, all embedded in a polymeric resin, such as cold-cured silicone resin. Nodes protect, enclose, insulate electrically, and otherwise protect the micro-coils. Connectors between nodes provide mechanical stability against breaking of wires, while permitting folding, bending, buckling, and otherwise deflecting to position the nodes as desired with three degrees of freedom.
US11213690B2 Wafer level packages of high voltage units for implantable medical devices
A multi-chip modular wafer level package of a high voltage unit for an implantable cardiac defibrillator includes one or more high voltage (HV) component chips encapsulated with other components thereof in a polymer mold compound of a single reconstituted wafer, wherein all interconnect segments are preferably located on a single side of the wafer. To electrically couple a contact surface of each HV chip, located on a side of the chip opposite the interconnect side of the wafer, the reconstituted wafer may include conductive through polymer vias; alternately, either wire bonds or layers of conductive polymer are formed to couple the aforementioned contact surface to the corresponding interconnect, prior to encapsulation of the HV chips. In some cases one or more of the components encapsulated in the reconstituted wafer of the package are reconstituted chips.
US11213689B2 Estimating shock success by monitoring changes in spectral data
This document presents a system for managing treatment for an emergency cardiac event. The system includes memory, one or more electronic ports for receiving ECG signals, and a treatment module executable on one or more processing devices. The module is configured to perform a number of transformation on portions of an ECG signal into frequency domain data, obtain one or more previous values derived from one or more time segments of the ECG, and determine, based on the frequency domain data a first value and a second value, determine a probability of therapeutic success. The module is further configured to cause one or more output devices to present an indication of the probability of therapeutic success.
US11213688B2 Utilization of a non-wearable coil to remotely power a cochlear implant from a distance
An exemplary system includes a sound processor configured to wirelessly communicate, while operating in a first mode, with a cochlear implant by way of a wearable headpiece coil configured to be worn on a head of a recipient of the cochlear implant, a non-wearable coil configured to be located away from the recipient, and an interface device configured to provide operating power to the non-wearable coil and communicatively couple to the sound processor while the sound processor is operating in a second mode. While the sound processor is coupled to the interface device and operating in the second mode, the non-wearable coil is configured to provide radio frequency (RF) power to the cochlear implant to keep the cochlear implant listening for commands from the sound processor.
US11213683B2 Systems and methods for selective memory enhancement and/or disruption
Systems and methods are disclosed for selectively reinforcing or weakening memory associations. At least one current generator provides an electrical current including a plurality of oscillating pulses with at least one predetermined frequency. A user interface includes at least one output device for delivering a sensory stimulus to a user and at least one user input device for registering a response to the stimulus. At least one processor determines from the response, based on at least one predetermined standard, whether an underlying memory association is desired or undesired and respectively sets the at least one predetermined frequency to be a beta or theta frequency. Consequently, the electrical current is generated and administered, via at least one electrode pair, thereby stimulating at least one specific portion of the user's brain so as to reinforce or weaken the underlying memory association.
US11213678B2 Method of manufacturing a medical device for neuromodulation
Catheter apparatuses, systems, and methods for achieving neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a therapeutic assembly that includes an elongated tubular shaft having a pre-formed spiral shape when in a deployed state (e.g., a radially expanded, generally spiral/helical shape) and a thermocouple assembly helically wrapped about the shaft. In one embodiment, the thermocouple assembly comprises first and second wires composed of dissimilar metals with the first wire including a plurality of exposed and insulated regions along the distal portion of the treatment device. The exposed regions of the first wire define a plurality of energy delivery portions positioned to deliver electrical energy (e.g., RF energy, pulsed energy, etc.) to target tissue adjacent a wall of an artery (e.g., a renal artery) to heat or otherwise electrically modulate neural fibers that contribute to physiological function (e.g., renal function).
US11213673B2 Diffusion bonded lead connector
A medical device lead connector includes electrically conducting contact rings spaced apart by an electrically insulating ring and in axial alignment. The electrically conducting contact ring and the insulating ring having an interface bond on an atomic level.
US11213672B2 Wound healing electrode set
The set for the electrical stimulation of a patient, comprises a backing, at least one electrically active zone and a wire connected to said electrically active zone for connection to a stimulator. Said backing has the shape of a bandage or of a plaster.
US11213671B2 Electroporation system for controlled localized therapeutics delivery
Embodiments of the present invention provide an electroporation system comprising an electroporation probe having at least two contiguous electrodes configured to be inserted into biological tissue for electroporation treatment, and a pulse generator electrically connected to the probe and configured to drive the electroporation probe using a sequence of one or more electric pulses to cause current transmission through the probe and induce a non-uniform electric field in the biological tissue proximate the probe electrodes. Treatment tissue can be targeted by controlling the probe configuration, carrier solution characteristics and parameters of the electroporation pulse sequence to achieve predictable electroporation outcomes. This electroporation control method can also reduce potentially toxic effects of electroporation treatment.
US11213669B2 Pinch clamp devices, methods, and systems
A tube clamp closes a flexible tube by applying a pinching force to walls of the flexible tube. The clamp includes a housing connected to a circular flange, the circular flange including a tubular wall surrounding a central bore and including at least one slot in the tubular wall sized to accept the flexible tube. A pinching element is positioned inside the central bore and is rotatable about a central axis of the circular flange. The pinching element includes a pinching projection that has a cross-sectional shape bound by a partial circle, and the partial circle has a radius substantially same as an inner radius of the tubular wall.
US11213668B2 Male Luer with fluid path and vent path seals
A needleless connector includes a body having a fluid path, a vent path, and a male fitting. The needleless connector also includes a valve disposed within the male fitting. The valve is configured to move between a first configuration, in which the fluid path is blocked, and a second configuration, in which the fluid path is open. The needleless connector further includes a seal disposed around the valve. The seal is configured to separate the fluid path from the vent path in the first and second configurations. Moving the valve from the first configuration to the second configuration also opens the vent path. The seal maintains the separation between the fluid path and the vent path when the valve moves from the first configuration to the second configuration.
US11213666B2 Method for administering a medicament suitable for treating a migraine or cluster headache
A method for administering a medicament to a patient includes placing a fluid delivery apparatus with the medicament in contact with a portion of the skin of said patient. A flow rate of the medicament from the fluid delivery apparatus is adjusted such that the medicament is delivered to the patient for a predetermined time period. The fluid delivery apparatus includes a controller assembly having a body component defining an axis and a plunger component slidably coupled to the body component. The plunger is positionable between a first position in which the plunger is nearest to the body component and a second position in which the plunger component is furthest from the body component. A bias assembly is positioned between the body component and the plunger component. The bias assembly is configured to apply a two stage force profile to the plunger component.
US11213660B2 Non-compliant medical balloon
A non-compliant fiber-reinforced medical balloon comprises a first fiber layer and a second fiber layer embedded in a continuous matrix of thermally-weldable polymer material defining a barrel wall, cone walls and neck walls. The fibers of the first fiber layer have a pattern of different lengths and are divisible into a first group and a second group based on length. The length of the fibers of the second group varies progressively in accordance to their proximity to the fibers of the first group; the fibers of the second group closest to the fibers of the first group being longer than the fibers of the second group further from the fibers of the first group. The fiber of the second fiber layer winds circumferentially around the longitudinal axis of the balloon substantially over the entire length of the balloon.
US11213655B2 Control handle with rotational cam mechanism for contraction/deflection of medical device
A medical device has a distal member with a configuration that can be changed by means of a control handle with a control assembly employing a rotational cam, a shaft, and a pulley, where the rotational cam is rotationally mounted on a portion of the control handle for rotation by a user. The rotational cam operates on the shaft to move it proximally or distally depending on the direction of rotation which in turn rotates the pulley to draw or release a puller wire to change the configuration of the distal member of the medical device. The shaft is oriented along a diameter of the control handle. The shaft has two ends which extends through two axial guide slots in the portion of the control handle to sit two opposing helical tracks formed on inner surface of the rotational cam. The guide slots are parallel with the longitudinal axis of the control handle and therefore maintain the shaft's diametrical orientation as the rotational cam is rotated to move the shaft proximally or distally. Actuation of the puller wire by means of the control assembly can result in a change of the distal member's configuration, including deflection, contraction and/or expansion.
US11213654B2 Robotic catheter system with variable speed control
A robotic catheter procedure system includes a bedside system that has a percutaneous device, and an actuating mechanism configured to engage and to impart movement to the percutaneous device. The system also includes a workstation coupled to the bedside system. The workstation includes a user interface configured to receive a user input, ma display device configured to display an image, a control system operatively coupled to the user interface and the actuating mechanism. The control system is configured to generate a control signal and the actuating mechanism causes movement of the percutaneous device in response to the control signal. The control system is configured to slow movement of the percutaneous device via the actuating mechanism as an identified point on the percutaneous device approaches a structure requiring a change in direction of the percutaneous device.
US11213650B2 Process as well as gas heater for heating a carrier gas stream
A gas heater (1) and gas heater method heat a carrier gas flow. The gas heater includes a gas inlet (2) a gas outlet (3) and a connecting gas channel (4). A heating system (5), arranged in the gas channel, includes a heat exchanger (12) surface. The carrier gas at least partly flows over the surface to heat the carrier gas flow. The gas channel includes a first section (6), arranged upstream of the heat exchanger in a flow direction, and a second section (7) arranged downstream of the heat exchanger. A respective sensor (8a, 8b), for detecting a pressure value, is in the first and the second section or directly adjacent thereto. Pressure values are transmitted to a control and analysis unit (9) which ascertains a mass and/or volume flow of the carrier gas in the gas channel based on a pressure difference between the two pressure values.
US11213648B2 Cushion member with engaging element
A cushion member (10) is for use in a pressure support system (2) for delivering a flow of breathing gas to an airway of a patient. The cushion member includes an annular body (12) comprising a first end (14) and a second end (16) disposed opposite the first end, the body defining a passage (18) therethrough; a sealing portion (20) extending from the second end of the body into the passage, the sealing portion having an outer surface (21) structured to sealingly engage about the airway of the patient and an inner surface (23) disposed opposite the outer surface; and a support portion (22,24) extending from the second end of the body into the passage and terminating at a distal end (26,28). The distal end of the support portion engages a portion of the body at or about the second end.
US11213647B2 Full face respirator mask
A full face respirator mask includes a ring-shaped frame, a transparent face plate connected to an inner periphery of the frame, an air inlet extending through the face plate, and a cushion integrally molded to the frame and having an abutment portion. The frame has top, bottom, left and right parts. At least one protruding plate extends rearwardly and horizontally from the top part. The at least one protruding plate is embedded in the cushion body to push the abutment portion to abut tightly against the face of a user when the full face respirator mask is positioned on the face of the user.
US11213646B2 Breathable respiratory mask
A patient interface is disclosed which is comfortable for the user to wear and includes at least in part a moisture permeable or breathable area in the body of the patient interface. In another embodiment the patient interface is a strapless mask that is moulded to fit the contours of a user's face and maximise the mask-to-skin seal. An adhesive material is bonded to the mask cushion and is stamped in place to form substantially the same shape as the cushion such that it fits the facial contours of the user.
US11213641B2 Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat
A therapeutic device for treating conditions of a user's nasal cavities, sinuses, and/or ear canals includes a housing which the user may hold to apply the therapeutic device to the user, the housing including an inlet that allows air to enter the therapeutic device. An acoustic vibrator located within the housing provides an acoustic vibration to the user, and a power supply located within the housing provides power to the acoustic vibrator. A mask is connected to the housing and includes a nasal interface that is appliable around the nose of the user. A valve of the mask opens to allow the user to breathe through the inlet and closes to prevent the user from exhaling through the inlet. The mask further includes a diaphragm and a nasal cavity in which a user's nostrils are located when the nasal interface is applied to the user.
US11213640B2 Methods and devices with leak detection
Automated methods provide leak detection that may be implemented in a respiratory treatment apparatus. In some embodiments, the detection apparatus may automatically determine and score different types of leak events during a treatment session, including, for example, continuous mouth leak events and valve-like mouth leak events. The detection methodologies may be implemented as a data analysis of a specific purpose computer or a detection device that measures a respiratory airflow or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected leak. In some embodiments, the leak detector may determine and report a leak severity index. Such an index may combine data that quantifies different types of leak events.
US11213635B2 Receptacle section
A receptacle section for an aerosol provision article is described. The aerosol provision article is for generating a flow of aerosol in use. The receptacle section is arranged for having installed therein an activatable element for modifying, once activated, a property of the flow of aerosol. The receptacle section is arranged to apply, on installation of the activatable element in the receptacle section by a user, a force to the activatable element to activate the activatable element.
US11213633B2 Pen needle magazine
An attachable needle assembly (2) for use on a medication delivery pen (4), the needle assembly (2) comprising a housing (16) that engage the medication delivery pen (4), the housing (16) enclosing a plurality of needles (34) that pierce a reservoir septum (6) of the medication delivery pen (4), a plurality of needle posts (24) each securing one of the plurality of needles (34), and a needle assembly septum (60) enclosing the plurality of needles (34). The needle assembly (2) further including a plurality of integrated peel tabs (70) each detachably connected to one of the plurality of needle posts (24), wherein in a first position of the needle assembly (2), the plurality of needles (34) is disposed in the needle assembly septum (60), and in a second position of the needle assembly (2), one of the plurality of integrated peel tabs (70) is drawn out of the housing (16) to cause a selected needle (40) of the plurality of needles (34) to pierce the needle assembly septum (60) and be exposed for medication delivery.
US11213632B2 Safety syringe and safety mechanism for use in the same
The present invention discloses a safety syringe and a safety mechanism for use in the safety syringe. In one example, the safety syringe comprises: a barrel having a proximal end, a distal end and a cavity being between the proximal end and the distal end and defining a longitudinal axis, a needle holder extending distally from the distal end; a plunger having a distal portion inserted inside the barrel from the proximal end of barrel and a proximal portion located outside the barrel; a needle having a proximal portion inserted into a needle passage of the needle holder from the distal side of the needle holder and a distal portion located outside the needle holder, the needle being hollow and in fluid communication with the cavity of the barrel; and a safety mechanism mounted at least partially around the needle holder; at an unactuated position of the safety mechanism, the distal portion of the needle is not covered by the safety mechanism; at an actuated position of the safety mechanism, at least distal tip end of the needle is covered by the safety mechanism to prevent accidental contact with the distal tip end of the needle. According to the present disclosure, it is feasible to, upon assembling the syringe, first duly mount the safety mechanism, and then mount the needle. As such, the needle needs to be calibrated only once, and furthermore, the safety mechanism, before being actuated, does not interfere with the needle.
US11213627B2 Medicament injection device
A medicament injection device comprising a main body arranged to receive a medicament cartridge; a needle carrier carrying a needle, wherein the needle carrier is axially movable with respect to the main body; and a rotatable cap at a distal end of the device, wherein the cap is removably coupled to the needle carrier, a releasable arrangement between the main body and the cap comprising a guide element and a slotted link, wherein the slotted link is arranged to cause the guide element to follow a predefined path at least partly in an axial direction during rotational movement of the cap, thereby causing the needle carrier to move axially towards a proximal end of the device as the cap is rotated up to a predefined point, wherein the main body comprises a medicament cartridge holder comprising the guide element depending therefrom for engagement with the cap.
US11213624B2 Controllable drug delivery system and method of use
A drug delivery system is disclosed that includes a drug delivery device having a reservoir, a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient, and one or more controllable elements. The drug delivery system may further include one or more sensors coupled to the drug delivery device, and a controller coupled to the one or more sensors and the one or more controllable elements. The controller may be configured to use the one or more sensors to determine a condition or an operational state of the drug delivery device. Furthermore, the controller may be configured to control the controllable element based on the condition or the operational state of the drug delivery device and/or identity information stored in a memory onboard the device. A method for use with a drug delivery device is also disclosed.
US11213623B2 Infusion systems and related personalized bolusing methods
Infusion systems, infusion devices, and related operating methods are provided. A method of operating an infusion device involves determining a reference insulin absorption curve for the patient based at least in part on demographic data associated with the patient, determining a contextual adjustment factor based at least in part on a current patient context, calculating an adjusted insulin absorption curve for the patient as a function of the reference insulin absorption curve and the contextual adjustment factor, and determining a bolus dosage of the insulin based at least in part on the adjusted insulin absorption curve.
US11213622B2 Usability features for integrated insulin delivery system
Methods and systems for delaying alarms that include detecting an analyte level using an analyte sensor; and delaying the annunciation of an analyte alarm after the analyte level crosses an analyte threshold, wherein the delay is based on one or both of (1) a magnitude of difference between the analyte level and the analyte threshold and (2) a duration of time in which the analyte level has crossed the analyte threshold.
US11213620B2 Drug delivery devices with partial drug delivery member retraction
Methods, devices, and components are provided to reduce tissue resistive pressure during a subcutaneous drug delivery operation by increasing the size of the injection cavity by partially retracting the drug delivery member after inserting the drug delivery member to a subcutaneous position. The drug delivery devices described herein include a magnetic actuator operably coupled to a primary container assembly including a drug delivery member. Power can be selectively provided to the magnetic actuator by a controller to retract the drug delivery member a predetermined distance to relieve pressure in an injection cavity in a patient. A force sensor can provide the controller with a drug delivery member insertion force. The controller can then estimate a tissue resistive pressure based on the drug delivery member insertion force and determine the predetermined distance for the drug delivery member retraction based on the tissue resistive pressure.
US11213618B2 System for tissue dissection and aspiration
A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes. A tool is provided to aspirate excess fluid and tissue from the treatment area.
US11213616B2 Recharge solution for zirconium phosphate
The invention relates to devices, systems, and methods for mixing one or more solutions to generate a recharge solution having specified concentrations of a sodium salt and acid for recharging and disinfecting zirconium phosphate in reusable sorbent modules. The devices, systems, and methods can generate a recharge solution by a sorbent recharger that is introduced through the sorbent module to recharge and to disinfect the zirconium phosphate.
US11213614B2 Vascularized biphasic tissue constructs
Biphasic tissue constructs that include a scaffold having one or more channels, a vascular portion comprising a hydrogel at least partially disposed in the one or more channels, and a first bioactive growth factor and a second bioactive growth factor different from the first bioactive growth factor, the first bioactive growth factor localized to the scaffold and the second bioactive growth factor localized to the vascular portion. The first bioactive growth factor may be bone morphogenetic protein 2 (BMP2) peptide and the second bioactive growth factor may be vascular endothelial growth factor (VEGF) peptide.
US11213612B2 Hybrid scaffold suitable for regenerating animal tissues and process for producing the scaffold
A hybrid scaffold is disclosed which is made of materials that define peripheral layers designed to interface with the tissues in the implant site and one or more intermediate layers. The materials are combined to give the scaffold mechanical properties suitable for withstanding the stresses of the implant site. The materials are fibroin for the peripheral layers and polyurethane combined with fibroin for each intermediate layer.
US11213610B2 Biopolymer scaffold implants and methods for their production
Compositions and blends of biopolymers and bio-acceptable polymers are described, along with the use of benign solvent systems to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries.
US11213608B2 Compositions including gelatin nanoparticles and methods of use thereof
Described herein are gelatin nanoparticles including their use in a composition. The composition may comprise a plurality of gelatin nanoparticles, at least one polymer, and water. In some embodiments, the composition comprises cells. The composition may be in the form of a hydrogel. Methods of using such gelatin nanoparticles and/or compositions are also described.
US11213606B2 Soft hydrophobic acrylic materials
Soft hydrophobic acrylic materials with improved resistance to fluid diffusion and suitable mechanical properties that allow deformation upon application of force are disclosed. The acrylic materials are particularly suitable for use in fluid-based accommodating intraocular lenses and comprises combination of a perfluoro-substituted alkyl (meth)acrylate and an alkyl (meth)acrylate, and a cross-linking agent.
US11213604B2 Composition for dressing cutaneous lesions and manufacturing method thereof
The invention relates to a composition for dressing cutaneous lesions, in particular cutaneous leishmanial lesions or cutaneous lesions due to actinic keratosis, comprising, based on the total weight of the composition:—10.0 weight percent to 35 weight percent of a one or more diols, selected from the group comprising 1,2-propylene glycol, 1,2-pentanediol, 1,3-butanediol and 2,2′-[Ethane-1,2-diylbis(oxy)]di(ethan-1-ol),—2.0 weight percent to 20 weight percent of at least one first film-forming agent, selected from one or more of a cellulose derivative, hemicellulose, a hemicellulose derivative, chitosan, a chitosan derivative, or oligoglucosamines,—0.2 to 25.0 weight percent of at least one elastic second film-forming agent, selected from one or more thickening agents,—0.2 to 25.0 weight percent of one or more polymeric surfactants,—0.005 to 0.5 weight percent chlorate-free chlorite,—water adding up to 100.0 weight percent.
US11213603B1 Ultraviolet-c (UV-c) light emitting diode (LED) irradiated forced airflow face shield
Disclosed herein is a forced irradiated air shielding mechanism that is an effective protective measure against Covid-19. The UV-C irradiated forced air flow face shield described herein is compact enough to be camouflaged under a cap. In this work it is mathematically proven that the described UV-C irradiated forced air flow face shield by itself provides more effective protection against the Covid-19 or similar airborne pathogens. The shield can be enabled using a mercury discharge tube or light emitting diode (LED) irradiator. Computational fluid dynamics is presented to show that positive irradiated air pressure ensures that the only air breathed by the wearer is irradiated. Also presented is a face shield testing apparatus.
US11213602B2 Multi-oil diffuser
An essential oil reflux-type atomizer comprising the following structures: a chassis, housing, atomization chamber, gas pump, gas tube, gas nozzle, oil nozzle, and filter atomization mechanism. Oil and gas flow together at the gas and oil nozzles to disperse and atomize the oil in the gas flow. A heater is used to raise the temperature of the oil where it is atomized, either by heating the oil itself or by heating the gas flowing into the oil. Thus, the atomizer can have improved performance, especially with essential oils having high viscosity and molecular weight.
US11213595B2 Antigen responsive antibody-fluorescent dye conjugate and method for fluorescence detection and imaging of target cell using the same
The present invention relates to an antibody-fluorescent dye conjugate capable of cancer cell-specific fluorescence imaging diagnosis. The fluorescent dye comprises a covalently labeled antibody and is quenched by interaction with an amino acid residue such as tryptophan, tyrosine, histidine, and methionine in the antibody and upon binding of the antibody to an antigen present on a cell surface to emit fluorescence, whereby cells having a target antigen thereon can be imaged for diagnosis. When using the antibody-fluorescent dye conjugate according to the present invention during in vitro cell assays, high-throughput screening of cells, and cytodiagnosis based on microfluidics, the presence of cancer cells having a specific antigen expressed thereon can be detected at high specificity and sensitivity without a washing process, and the position of primary and metastatic cancer cells can be detected at high contrast within a short time.
US11213594B2 Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids
Disclosed are compositions for delivering gene editing molecules to a cell. Exemplary compositions comprise a micelle assembled from a plurality of triblock copolymers, wherein each triblock copolymer having at least one hydrophobic block, at least one hydrophilic block, and at least one poly(L-histidine) block, wherein: the at least one poly(L-histidine) block complexes with the at least one gene editing molecule; and the at least one poly(L-histidine) block is capable of a pH dependent release of the at least one gene editing molecule.
US11213592B2 Antibody-sting agonist conjugates and their use in immunotherapy
The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.
US11213589B2 Additive systems for use in protein PEGylation
The present disclosure provides an additive system for use in protein PEGylation. The additive system includes p-aminobenzoic hydrazide used either alone or in combination with aromatic amines, such as 3,5-diaminobenzoic acid, or with ammonium salts such as ammonium chloride or ammonium acetate. The disclosed additive combination provides several benefits including increased reaction rates, higher yields and reduction in the aminoxy-PEG equivalents required to complete the conjugation reaction. Typical reactions can be run by combining the additive or additive system with a solution of a protein and aminoxy-PEG reagent. The solution is adjusted to pH 4 and held at 20-25° C. without stirring until completion, typically within 24 hours.
US11213586B2 Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR)
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
US11213585B2 Vaccines for use in treating various diseases and disorders
Various diseases and disorders associated with cellular senescence may be treated by immunizing a subject in need thereof against AGE-modified proteins or peptides of a cell Immunizing a subject includes administering a vaccine that comprises an AGE antigen. Vaccines against AGE-modified proteins or peptides contain an AGE antigen, an adjuvant, optional preservatives and optional excipients.
US11213577B2 Treatment of cancer using recall antigens delivered by attenuated bacteria
Methods, pharmaceutical compositions and vaccines comprising an attenuated bacteria that expresses a recall antigen are disclosed for treatment of cancer.
US11213576B2 Vaccine comprising allogeneic T-cells
The invention disclosed herein relates generally to immunotherapy and, more specifically, to the use of immunotherapy for treating tumors and pathogen infected tissues by first priming patients with allogeneic cells designed to be rejected by a Th1 mediated mechanism, then inducing necrosis or apoptosis in a tumor or pathogen infected lesion by methods such as cryotherapy, irreversible electroporation, chemotherapy, radiation therapy, ultrasound therapy, ethanol chemoablation, microwave thermal ablation, radiofrequency energy or a combination thereof applied against at least a portion of the tumor or pathogen infected tissue, and then delivering one or more doses of allogeneic cells (e.g., Th1 cells) within or proximate to the tumor or pathogen-infected tissue in the primed patient. The present invention provides an immunotherapeutic strategy to develop de-novo systemic (adaptive) immunity to a tumor or pathogen.
US11213571B2 Modulation of cancer immunity with type 2 innate lymphoid cells, interleukin 33, and/or interferon induced protein 44
The present invention provides methods of modulating of cancer immunity using type 2 innate lymphoid cells (IL-C2s), interleukin 33 (IL-33), IFI44 or combination thereof. Also provided are methods of preventing tumor metastasis and/or cancer progression by treatment with therapies comprising type 2 innate lymphoid cells (ILC2s), interleukin 33 (IL-33), IFI44 or combination thereof. Also provided are diagnostic methods for assessing cancer prognosis.
US11213570B2 Use of C1q/TNF-related protein-1 (CTRP1) to treat fatty liver disease
Methods for the treatment or prevention of disease, such as fatty liver disease and obesity, are described including the modulation the amount of CTRP1 in a subject. Novel mouse strains are also described.
US11213568B2 Nerve growth factor mutant
Provided is a nerve growth factor mutant, wherein same is an amino acid sequence as shown by any one of SEQ ID No: 3 to SEQ ID No: 21 in the sequence listing. The advantage of the nerve growth factor mutant lies in that the mutation of a nerve growth factor can alleviate side effects such as pain, falling within the field of biological pharmacy.
US11213566B2 Oral care compositions and methods
Provided herein is a pharmaceutical or oral care product for treating or preventing oral diseases that is prepared with proteoglycan 4 (PRG4) as an active ingredient, the preparing method thereof and the use thereof in manufacturing medicaments or oral care products for treating or preventing oral diseases and maintenance of oral health. PRG4 may have efficacy in maintaining oral health and treating or preventing oral disease. This secreted glycoprotein, which is also called lubricin and superficial zone protein, is known to protect against frictional forces, cell adhesion and protein deposition.
US11213561B2 Herbal methods for the improvement of sleep, social interaction, concern or worry
Methods for, among other things, improving sleep, energy and social interaction and reducing concern or worry in mammals are provided. In one embodiment, the method includes administering a tablet, capsule or caplet of 190 mg to 3200 mg of compositions that include extracts of Crateva nurvala, Equisetum arvense, Lindera aggregata, and Zea mays daily.
US11213560B2 Method of promoting wound healing with sinetirucallol
The present disclosure provides compositions and dosage forms comprising sinetirucallol, and methods of using such compositions, such as to treat an inflammation-associated disease, liver fibrosis, wound healing, and/or an autoimmune disease. In some embodiments, the composition comprises a Spiranthes sinensis extract.
US11213559B2 Formulation for treatment of irritable bowel disease
The present invention relates to an effective formulation for the treatment or the prevention of irritable bowel syndrome, a method for treating irritable bowel syndrome, and processes for preparing such formulations.
US11213555B2 Intravenous injection for enhancing immune function
An intravenous injection for enhancing immune function is provided, belonging to the field of biomedicine. The main ingredient of the drug is inactivated lactic acid bacteria, which is prepared by inactivating living lactic acid bacteria.
US11213554B2 Composition for improving the health of livestock
A method for the prevention or treatment of infections contracted by newborns of livestock mammals, which includes applying a composition that includes a mixture of bacterial strains to the perineum and/or the teat(s) of female livestock mammal that is going to give birth or has given birth to the newborn livestock mammals. Also, a kit for preventing digestive, respiratory or other infections in newborn livestock mammals, which includes at least one composition and at least one application element for applying the composition to the perineum and/or to the teats of the female livestock mammals.
US11213553B2 Hypolipidemic effects of Bacillus coagulans
Disclosed is the hypolipidemic potential of Bacillus coagulans. More specifically the invention discloses the cholesterol lowering potential of Bacillus coagulans MTCC 5856 and therapeutic/biological indications thereof.
US11213548B2 Modulatable switch for selection of donor modified cells
The disclosed methods are generally directed to preventing, treating, suppressing, controlling or otherwise mitigating side effects of T-cell therapy, the T-cell therapy designed to accelerate immune reconstitution, induce a GVM effect, and/or target tumor cells.
US11213544B2 Application of alginic acid sulfate in preparation of drugs and health care products for preventing and treating diseases caused by human papilloma viruses
An application of alginate sulfate in the preparation of drugs and health care products for preventing and treating diseases caused by human papillomavirus. Alginate sulfate has a strong dose-dependent inhibitory effect on HPV infection through experiments, and alginate sulfate inhibited the expression of E6 and E7 genes and proteins in HPV-transformed Hela and Caski cells in a dose-dependent manner. The alginate sulfate can be developed into a drug or a health care product against human papillomavirus by systematic scientific experiments, which will have a good market application prospect.
US11213535B2 Composition containing phytic acid, magnesium and polyphenols for the treatment or prevention of renal lithiasis
The present invention is related to a composition comprising phytic acid or a phytate salt, magnesium in the form of salt, hydroxide or oxide and optionally at least one polyphenol. These components may be in isolated form or be part of an enriched plant extract. The invention is also related to the use of this composition for the treatment of renal lithiasis, preferably calcium or calcium oxalate lithiasis, either in the form of a medicament, a nutraceutical or functional food or food supplement.
US11213532B2 Therapy and prevention of prion protein complex infections in non-human animals
There are disclosed therapies and preventions of prion protein complex infections. The transcription of the amyloid precursor protein gene and PrP gene and the RNA transcript are the rate-limiting steps and are most susceptible for blockage and control of the process of amyloid protein formation and PrPsc formation. Thus, therapies and prevention regimes for prion protein complex infections interrupt this process at the level of DNA transcription to RNA, RNA transport to the mitochondrion for protein synthesis and deposition in the cerebral cortex neurons.
US11213529B2 Salt of substituted urea derivative and use thereof in medicine
A salt of a substituted urea derivative of formula (I) and use thereof in the pharmaceutical field. Also, a pharmaceutical composition containing the salt or a combination thereof, and use of the salt or the pharmaceutical composition in the manufacture of a medicament for treating, remitting or preventing a disorder related to tyrosine kinase activity.
US11213528B2 Salts of the janus kinase inhibitor (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
US11213525B2 Linear glycosidase inhibitors
Compounds of formula (I), wherein A, R, W, Q, L, n and m have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.
US11213524B2 Pharmaceutical compositions for subcutaneous administration of levosimendan
A composition containing levosimendan, one or more solubilizing and/or stabilizing agents, and one or more additional pharmaceutically acceptable additives. The one or more solubilizing and/or stabilizing agents may be a cyclodextrin or a cyclodextrin derivative. The cyclodextrin derivative may be a derivative of an alpha-cyclodextrin, or beta-cyclodextrin, or a gamma-cyclodextrin. The cyclodextrin derivative may contain a butyl ether spacer group, an alkyl ether space group, or both. The one or more additional pharmaceutically acceptable additives may be a non-citrate buffer. The composition may be used in a method of treating a health condition, such as heart failure, pulmonary hypertension, chronic kidney disease, amyotrophic lateral sclerosis, stroke, in advance of a planned cardiac surgery, or other health conditions for which a minimally invasive or repeated administration of levosimendan may be beneficial. The composition may be administered subcutaneously.
US11213523B2 Substituted pyrido[1,2-a]pyrrolo[1,2-d]pyrazines for treating viral infections
Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein L, R1, R5, W, X, Y1, Y2, and Z are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
US11213522B2 Autoimmune-induced glutamatergic receptor dysfunction methods and treatments
This invention provides a method of enhancing NMDAR-mediated neurotransmission in a disease associated with NMDAR antibody production, said method comprising administering an NMDAR agonist, an alanine-serine-cysteine transporter inhibitor, a D-amino acid oxidase inhibitor, a glycine transport inhibitor or a combination thereof to said subject. This invention also provides a method of mitigating the severity of, mitigating the pathogenesis of, lowering the incidence of or treating a disease associated with NMDAR antibody production, said method comprising administering an agent, which is an NMDAR agonist, an alanine-serine-cysteine transporter inhibitor, a D-amino acid oxidase inhibitor, a glycine transport inhibitor or a combination thereof to said subject.
US11213521B2 Bupropion as a modulator of drug activity
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.
US11213512B2 Bis-amino acid based compound and use thereof
Compositions comprising bis(tryptophan) derivatives are provided that act as antimicrobials. Also provided are methods for reversing antibiotic resistance in a bacterium, or recovering or enhancing antimicrobial activity of an antibiotic against a variety of microbes, by co-administration with a bis(tryptophan) derivative.
US11213510B2 Thioindirubins
Disclosed herein inter alia are compositions and methods for treating cancer using thioindirubin derivatives.
US11213506B2 Combination therapy for the treatment or prevention of tumours
The present invention relates to a combination therapy for tumours comprising the administration of an epoxytigliane compound and an immune checkpoint inhibitor. In particular embodiments, there is a method of treating a tumour and/or treating or preventing one or more bystander tumours with the therapy. Pharmaceutical compositions and kits containing epoxytigliane compounds and immune checkpoint inhibitors are also described.
US11213505B2 Product based on iron bis-glycinate chelate and alginic acid and/or water-soluble salts thereof, formulations thereof, and pharmaceutical uses thereof
The object of the present invention is a product obtainable by spray-drying an aqueous solution comprising iron bis-glycinate chelate and alginic acid and/or water-soluble salts thereof, preferably sodium alginate, potassium alginate and/or magnesium alginate, the use of said product for the prevention and/or treatment of anaemia, preferably sideropenic anaemia, in humans, the pharmaceutical formulations containing it, and the use of said formulations for the prevention and/or treatment of anaemia, preferably sideropenic anaemia, in humans.
US11213499B1 Use of 3,3′-diselenodipropionic acid (DSePA) as an anticancer agent
The present invention describes the method of using a synthetic organoselenium compound, DSePA for management of non-small cell lung carcinoma (NSCLC) and chronic myelogenous leukemia (CML). The method comprises administering DSePA orally at a dosage of 1 mg/Kg body weight daily for inhibiting the growth of A549 (representative of NSCLC) and K562 (representative of CML) tumor in mice models. Additionally, the said compound also inhibits the proliferation of other cancer cells of NSCLC (HOP-62 and H460), breast (MDA-MB-231), white blood cells (JURKAT and U-937), oral (SCC-40), colon (HT-29), kidney (A498) and cervix (SiHA) origins in cellular models at a much lower concentration than that needed to inhibit the growth of normal cells.
US11213497B2 Antibiofilm formulations
Methods and compositions related to molecules and formulations comprising antibiofilm materials are provide, including new formulations of Deep Eutectic Solvents (DES) that are chemically related to choline geranate. Specifically, geranic acid (a component of choline geranate DES) is a molecule from the isoprenoid/terpene family of compounds. Other members of this family as DES components include isoprenoid acids and chemical derivatives thereof.
US11213495B2 Method and composition for decreasing the psychotomimetic side effect and addictive disorder of ketamine
The present invention relates to a method for decreasing the psychotomimetic side effects and enhancing the antidepressant-like effects of ketamine by the combination of ketamine with a methylglycine derivative. The present invention also relates to a method for depression treatment comprising administrating ketamine combined with a methylglycine derivative. The present invention further provides a method for preventing or treating addictive disorders of ketamine by administrating a methylglycine derivative.
US11213494B2 Compositions and methods for the treatment of pervasive development disorders
A method of treating a pervasive development disorder in a subject includes administering to the subject a therapeutically effective amount of an NMDAR antagonist, with an intermittent dosing regimen.
US11213492B2 Antiseptic composition comprising unithiol and dimethylsulfoxide, use of the composition and method of wound treatment with its use
Colloidal antiseptic compositions for treating wounds and/or for use in surgical operations are provided. The compositions form an elastic air- and water-permeable biodegradable film on the wound surface and have antiseptic, hemostatic, anti-inflammatory, wound-healing, and especially anesthetic and antitoxic effects. The compositions include a collagen hydrolysate, one or more salts of alginic acid and one or more antiseptics, and additionally include unithiol and dimethylsulfoxide. The compositions may also optionally include one or more anesthetics.
US11213487B2 Negatively charged self-assembling supported lipid bilayer on mesoporous silica nanoparticles, method of synthesis and use as a nanovector
A method for manufacturing a negatively charged supported lipid bilayer. The method comprises the steps of preparing a formulation comprising at least three lipids (1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS), cholesterol and at least one lipid different from DOPS and cholesterol) dissolved in a first solvent, of evaporating the first solvent, of adding an aqueous formulation of mesoporous silica nanoparticles, of performing an ultra-sonication and of performing a centrifugation. The method is remarkable in that the number of equivalents of cholesterol relative to one equivalent of DOPS is comprised between 2.30 and 2.70. Additionally, negatively charged supported lipid bilayer on a mesoporous silica nanoparticle comprising cholesterol, 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) and at least one lipid different from DOPS and cholesterol.
US11213484B2 Dipivefrin orally disintegrating tablet formulations
This disclosure provides orally disintegrating dipivefrin tablet (ODT) formulations, including ODT formulations containing L-dipivefrin HCl. The ODT formulations of the disclosure include 10 to 70% binder (wt %), 5 to 50% matrix former (wt %), and 1 to 20% taste masking agent (wt %). The ODT formulations of the disclosure rapidly provide epinephrine to a patient when administered. The disclosure also provides a method of treating a patient who has a condition responsive to epinephrine such as a cardiac event, asthma, croup, cancer, a microbial infection, Addison's disease, or an allergic reaction, particularly anaphylaxis by administering an orally disintegrating dipivefrin tablet formulations to the patient.
US11213480B1 Phenylephrine hydrochloride ready-to-use solution
This invention relates to a dilute, ready-to-use solution of phenylephrine hydrochloride having improved stability and utility. In a particular embodiment, the formulation consists of an injectable form of phenylephrine hydrochloride with edetate disodium chelating agent in place of any sodium metabisulfite antioxidants to improve the solution's ability to remain stable and active in a dilute state after prolonged storage. This invention also relates to a form for injection of the solution that includes packaging the solution in a single-use container, as well as a form for containing the ready-to-use solution in a sterile, sealed container. Lastly this invention relates to methods of making the injectable solution for use in a single-use container, as well as for containment in a sterile, sealed container.
US11213477B2 Cosmetic composition comprising a Chaga extract and use thereof
The present invention relates to a cosmetic composition comprising an extract from Inonotus obliquus (Chaga) and in particular to a cosmetic composition comprising: (i) a chaga extract at a concentration of at least about 2.5 mg/ml; and (ii) one or more physiologically or pharmaceutically acceptable excipients and/or diluents, wherein the chaga extract comprises at least about 1% (w/w) of β-glucans and/or at least about 0.10% (w/w) of polyphenolics.
US11213475B2 Multi-layer peelable nail polish
A method and system for a multi-layer peelable nail cosmetic compositions are disclosed. The multi-layer system includes a water-washable, non-UV curable nail basecoat composition in a hand-held, non-pressurized container. The basecoat composition includes a hydrophilic poly(N-vinyl)lactam polymer, at least one alcohol, and at least one plasticizer. The multi-layer system also includes a colored non-UV curable nail colorcoat composition that includes a primary film former, a secondary film former, a plasticizer, and a colorant.
US11213473B1 Skin brightening composition
A composition to improve hyperpigmentation is disclosed. The composition has one or more active ingredients such as tranexamic acid, niacinamide, arbutin, and Vitamin C. The composition has water, caprylic/capric triglyceride, C12-15 Alkyl Benzoate, Isononyl Isononanoate, Silica, Glyceryl Stearate and PEG-100 Stearate, Cetearyl Alcohol and Ceteareth-20, Xylitylglucoside and Anhydroxylitol and Xylitol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Phenoxyethanol and Ethylhexylglycerin, Citric Acid, Titanium Dioxide, Citrus oil, sh-Polypeptide-22, and sh-Oligopeptide-1. The composition is a non-HQ formulation that provides equal or greater efficacy with a reduced adverse reaction profile to improve skin hyperpigmentation, such as melasma, post-inflammatory hyperpigmentation, and solar lentigines. The composition reduces skin damage and provides toning to the skin.
US11213470B2 Compositions for treating the hair
The disclosure relates to compositions for treating keratinous substrates, such as the hair, comprising at least one monoamine and at least one carboxylic acid, as well as systems and methods for treating keratinous substrates with the compositions.
US11213469B1 Effervescent foot bath and method
An effervescent foot bath which employs an acid in combination with a carbonated base to produces a effervescing effect in a closed foot tub. The reaction has been designed to function externally to soften and begin the process of removing dry, rough peeling skin from the feet.
US11213458B2 System and method for monitoring intake compliance
A product interaction monitor includes sensors for measuring characteristics related to the product and/or product package or other type of container. The product interaction monitor can be installed in a container cap and used to monitor events associated with the container such as product usage. The product interaction monitor can utilize multiple sensor outputs to increase the accuracy of the detection of the events. The product interaction monitor can be used to estimate product inventory or product usage and communicate information regarding the product and/or product usage to a local display or a remote computer.
US11213453B2 Treatment for large volume biological targets with a high pressure shockwave instrument
The present invention relates to a device, system and a method for high pressure shockwave treatment of biological tissue having a large treatment zone and in particular to such a device, system and method in which a large biological treatment area in treated in a non-drug, non-surgical treatment protocol utilizing ballistic shockwave generating device.
US11213450B2 Travel motion assist device
Provided is a travel motion assist device capable of assisting a travel motion of a user without causing any discomfort, and has a high level of versatility. A travel motion assist device includes an assist drive unit configured to be worn on a prescribed joint of the user required for the travel motion of the user, and to be driven in a corresponding manner, a torso motion detection unit configured to be worn on a torso of the user, and to detect the displacement of a center of gravity C indicating the movement of the torso, and a control unit configured to control an operation of the assist drive unit, wherein the control unit estimates a phase of the travel motion of the user according to a detection result of the torso motion detection unit, and drives the assist drive unit at a prescribed phase.
US11213443B2 Indication system to identify open space beneath patient support apparatus
A patient support apparatus includes a support structure having a base and further includes an indication system having one or more clearance sensors configured to detect clearance within a clearance zone between the patient support surface and a floor surface and are also configured to generate one or more clearance signals corresponding to the detected clearance. The indication system also includes a controller coupled to the clearance sensors that is configured to receive the one or more clearance signals and generate an output based upon the received clearance signals. A display coupled to the controller is configured to receive the generated output and generate a visual clearance indication corresponding to the detected clearance within the clearance zone, or in specific predefined portions of the clearance zone, that is viewable in a viewing area of the display.
US11213439B2 Modular stretcher or litter
A stretcher which comprises a bed, and a frame having first and second parallel frame members coupled to first and second lateral frame members is disclosed. A securement track is define by an upper surface of at least one of the first parallel frame member, the second parallel frame member, the first lateral frame member, and the second lateral frame member, the securement track having a plurality of alternating open regions and necked down regions along a length. A bed mount configured to both support the bed and be releasably secured in the securement track in a secure condition, and configured to be repositionable along the length of the securement track in an unsecured condition.
US11213438B2 Disposable wearable absorbent article
A disposable wearable absorbent article comprises a chassis having an absorbent core and first and second side panels extending transversally outwards towards respective outer edges. Each of the first and second side panels comprises a mechanical fastening material affixed to an outer end portion of the panel whereby, in use, the first and second side panels can extend around a user's waist to couple the first and second side panels to the chassis. Each of the side panels is gathered in a longitudinal direction to form at least one pleat extending in the transverse direction, and comprises a binding material affixed to respective side panels to maintain each of the first and second side panels in a gathered configuration. A method for forming disposable wearable absorbent articles is also disclosed.
US11213435B2 Underpants-type disposable diaper
A cover nonwoven fabric covers a back surface of an inner member from between a front side outer member and the inner member to between a back side outer member and the inner member. In this cover nonwoven fabric, a large number of holes are provided at intervals. The holes penetrate the front surface and back surface from between the front side outer member and the inner member to between the back side outer member and the inner member. The front side outer member and the back side outer member have, at least at portions overlapping with the cover nonwoven fabric and not having any elastic member, a total luminous transmittance of 50% or more.
US11213432B2 Transparent cover dressing application system and inclusion of label strip
A dressing having a multilayer assembly in which dressing includes a polyurethane dressing layer that is adhesively secured over a wound or other location on a user's skin. Label strips that can be incorporated into the dressing. The label strips can include text, indicia, logos, or other markings which are applied to the strip prior to or after application of the dressing.
US11213430B2 Inner ear plug
Embodiments are generally directed to a securable inner drug delivery plug or stopper that is configured to be inserted into, and secured (retained) within, an opening of the inner ear of an recipient. The securable inner drug delivery plug is configured to deliver drugs directly into the inner ear.
US11213426B2 Thermally robust multi-spot laser probe
A laser probe includes a cannula, at least one optical fiber positioned within the cannula, and a lens positioned within the cannula at a distal end of the fiber. The lens is adapted to receive a laser beam from the optical fiber at a proximal end of the lens and to transmit the laser beam towards a distal end of the lens. The laser probe includes an optical element configured coupled to the cannula by a brazed joint and to receive the laser beam from the distal end of the lens and emit the laser beam from the probe. The brazed joint may form a hermetic or liquid-tight seal between the optical element and the cannula.
US11213421B1 Device and method for reducing urinary retention
A device to facilitate urination by a male includes a vessel having a contact surface area at and adjacent a top edge of the vessel configured to be placed in contact with the penis. The contact surface area includes a thermally conductive material and has a shape configured to reduce hydrostatic pressure requirements for urination from a standing position as compared with urinating into a toilet from a standing position. A method of reducing urinary retention in a male includes contacting the penis of the male with a contact surface area of a device, which may be as described above, and urinating while the male is in a standing position with the penis in contact with the contact surface area, wherein the contact surface area comprises a thermally conductive material and is at an initial temperature at least 14° F. lower than a temperature of the penis.
US11213420B2 Coupling system for an ostomy appliance
Embodiments provide a coupling system (3) for an ostomy appliance (1) comprising a sealing wafer (5) and a collecting bag (7). The coupling system comprises a first coupling part (9) and a second coupling part (11). The first and second coupling parts each encircle a stoma-receiving opening (17). The first and second coupling parts are configured to connect the sealing wafer to the collecting bag. The first coupling part comprises a first base portion (33), a second base portion (35) and a connecting portion (37) extending between the first and second base portions. The first base portion is arranged radially closer to the stoma-receiving opening than the second base portion. The first coupling part comprises an enclosed volume of air (10). The enclosed volume of air is enclosed at least in part by the first base portion, the second base portion and the connecting portion.
US11213415B2 Medical device delivery systems and methods
Medical device delivery systems and methods are disclosed. In various examples, the medical device delivery system (1000) includes an elongate element (1100) including an olive (1200). The olive (1200) includes an opening that exposes a lockwire (1300) extending through a lumen of the olive (1200) such that a linking element (1500) can be coupled to the portion of the lockwire (1300) exposed by the opening, wherein the linking element (1500) provides a coupling to a medical device (1400).
US11213414B2 Controlled extension stent
The present disclosure relates generally to controlled extension medical stents, and more particularly to controlled extension devices positioned in the body to stent the ureter and facilitate drainage from the kidney to the bladder.
US11213408B2 Linear actuator for asymmetric power generation and dissipation
An asymmetric linear actuator is provided which integrates a hydraulic dissipater and an electric motor and power screw which generates small forces. The actuator is configured so that an electric motor drives a power screw which drives a rod through a cylinder to provide linear actuation. The cylinder is fluid-filled and incorporates a piston that separates the cylinder into a first and second fluid chamber which are filled with a first and second volume of working fluid. Movement of the piston and rod assembly results in fluid movement between the first and second volumes of working fluid and through the fluidic restriction. The fluidic restriction can be proportionally controllable via an electric motor which enables controllable power dissipation via control of the fluidic restriction motor and controllable power generation via control of the power screw motor.
US11213405B2 Implant with structural members arranged around a ring
An implant for use in a spine includes a body and a plurality of structural members. The superior and inferior surfaces each include a ring and structural members arranged in a web-like pattern around the ring. Bone contacting members are arranged radially away from the ring and support members are arranged in a circumferential direction around the ring.
US11213403B2 Devices and methods for optimized spinal fixation
Devices and methods are provided for optimized spinal fixation using additive manufacturing techniques to create implants with optimized structure for various surgical approaches, anatomies, etc. One exemplary embodiment includes a cage having an X-shaped connection that can bear a load during cage impaction. The cage can be additively manufactured to incorporate features such as variable wall thickness or material density to adjust properties of the cage, including load bearing capability, flexibility, radiolucency, etc. The cage can further include one or more of the connectors disposed between upper and lower endplates. In some embodiments, the cage can include a feature for coupling an insertion device thereto for introducing the cage into the body of a patient. In some embodiments, a plate can be appended to or integrally formed with a proximal end of the cage to assist with securing the cage to vertebral bodies.