最新美国发明专利第2021-12-28期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US11208480B2	Multispecific antigen binding proteins Multimeric multispecific proteins formed from dimerization between CH1 and CK domains and that bind two target antigens are provided. The proteins have advantages in production and in the treatment of disease, notably cancer or infectious disease.
US11208479B2	CX43 hemichannel antibodies and methods of use Methods for identifying compounds that positively regulate connexin 43 hemichannels.
US11208477B2	Antibodies and use thereof The present invention relates to specific antibodies and use thereof, such as for identifying and/or quantifying liraglutide fibrils and/or semaglutide fibrils.
US11208473B2	Antibody binding a linear epitope of human P53 and diagnostic applications thereof The invention relates to an anti-human p53 antibody suitable for specifically binding a linear epitope which is exposed only in a conformationally altered isoform of the characteristic p53 protein of patients with Alzheimer's disease or prone to develop Alzheimer's disease or cognitive impairment during ageing. Methods and diagnostic and prognostic kits are also described.
US11208472B2	Engineered antibody for inhibition of fibrosis A chimeric, humanized or single-chain antibody contains a light chain variable region containing the complementarity determining regions of SEQ ID NO: 1, SEQ ID NO:2 and SEQ ID NO:3, and a heavy chain variable region containing the complementarity determining regions SEQ ID NO:5 and SEQ ID NO:6. The antibody or antibody fragment thereof is capable of binding the C-terminal telopeptide of the α2(I) chain of human collagen I, and is useful in the treatment of diseases or disorders associated with excessive collagen fibril.
US11208471B2	Method for treating infectious diseases using a composition comprising plasma-derived immunoglobulin M (IgM) Compositions and methods of the present invention prevent, inhibit or reduce the toxic effects of proteins and toxins secreted from microbes. A method for neutralizing microbial protein products in a subject comprises administering a composition to the subject, said composition comprising plasma-derived IgM and optionally one or more excipients in a pharmaceutical carrier, wherein the composition is administered in an amount effective to neutralize the microbial protein products.
US11208461B2	Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer The present invention concerns the use of interleukin-8 (IL-8) as a biomarker for predicting the outcome of the treatment with aflibercept, or ziv-aflibercept of a patient suspected to suffer from a cancer.
US11208459B2	Constructs having a SIRP-alpha domain or variant thereof The present disclosure features signal-regulatory protein α (SIRP-α) polypeptides and constructs that are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase phagocytosis of the target cell, to eliminate immune cells such as regulatory T-cells, to kill cancer cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The SIRP-α constructs include a high affinity SIRP-α D1 domain or variant thereof that binds CD47 with higher affinity than a wild-type SIRP-α. The SIRP-α polypeptides or constructs include a SIRP-α D1 variant fused to an Fc domain monomer, a human serum albumin (HSA), an albumin-binding peptide, or a polyethylene glycol (PEG) polymer. Compositions provided herein include (i) a polypeptide including a signal-regulatory protein α (SIRP-α) D1 variant and (ii) an antibody.
US11208450B2	GM-CSF variants and methods of use GM-CSF variants, polynucleotides encoding them, and methods of making and using the foregoing are useful in treatment of immune-related disorders, such as inflammatory bowel disease (IBD).
US11208447B2	Viral vector suitable for gene therapy encoding a variant of a BPIFB4 protein The present invention relates inter alia to a polynucleotide or viral vector encoding a variant of BPIFB4 (Bactericidal/Permeability Increasing protein family B, member 4) protein and to their use for the treatment of pathologies involving impairment of nitric oxide signalling.
US11208444B2	BRCA2-mediated purification of recombinase protein The invention is the products and methods associated with purifying overexpressed recombinant recombinases from a host cell line resulting in an un-tagged protein of interest without any additional, non-native amino acids. The invention employs at least one DNA vector that co-expresses a tagged fusion protein and the recombinase protein with the recombinase protein having an affinity for binding to the tagged fusion protein. Isolation methods of the recombinase protein include the targeting of the tagged fusion protein.
US11208441B2	Immunoglobulin-binding polypeptide An object of the present invention is to provide a polypeptide having a high binding capacity for an immunoglobulin kappa chain, and having excellent alkali stability, by modifying an amino acid sequence of an immunoglobulin-binding domain of Protein L derived from Peptostreptococcus magnus. A polypeptide having a high binding capacity for an immunoglobulin kappa chain, and having excellent alkali stability can be obtained by substituting specific lysine residues in an immunoglobulin-binding domain of Protein L derived from Peptostreptococcus magnus 3316 strain, with a basic amino acid or a hydroxyl group-containing amino acid.
US11208439B2	Mutant fragments of OspA and methods and uses relating thereto The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use as a medicament of in a method of treating or preventing a Borrelia infection) comprising the polypeptide and/or the nucleic acid, a method of treating or preventing a Borrelia infection and a method of immunizing a subject.
US11208435B2	Verticilide enantiomer and methods of inhibiting cardiac ryanodine receptor-mediated intracellular calcium release The non-natural enantiomer (ent-(+)-verticilide) and uses for treatment of RyR2-mediated spontaneous Ca2+ leak, arrhythmia and memory loss.
US11208434B2	Immunotherapy against several tumors including neuronal and brain tumors The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 30 peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
US11208431B2	Stable isotope-labeled compounds Provided are a novel internal standard useful in the measurement of androgens, a method capable of measuring the androgen in a highly selective and highly sensitive (accurate) manner using liquid chromatography mass spectrometry with simplified pretreatments, and a method for diagnosis of a disease using the androgen measurement method. The novel stable isotope-labeled compound is synthesized by performing reduction reaction in a specific solvent. An androgen is measured using this novel stable isotope-labeled compound as an IS.
US11208416B2	Selective inhibitors of protein arginine methytransterase 5 (PRMT5) The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.
US11208414B2	Ectonucleotidase inhibitors and methods of use thereof The invention relates to novel heterocyclic compounds having CD73 inhibitory activity and pharmaceutical preparations thereof. The invention further relates to methods of treating or preventing cancer using the novel heterocyclic compounds of the invention.
US11208411B2	Compositions and methods for treating parasitic diseases Disclosed herein, inter alia, are compositions and methods for treating parasitic diseases.
US11208410B2	Heterocycle-bound condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide In crop production in the fields of agriculture, horticulture and the like, the damage caused by insect pests etc. is still immense, and insect pests resistant to existing insecticides have emerged. To solve the problems, the present invention has been made, and an object of the present invention is to develop and provide a novel agricultural and horticultural insecticide.The present invention provides a heterocycle-bound condensed heterocyclic compound represented by the general formula (1): {wherein R1 represents an ethyl group, R2 represents a haloalkyl group, A1 represents a N-methyl group, A2 and A3 represent a nitrogen atom, n represents 1, m represents 2, and Q represents an oxadiazole}, or a salt thereof; an agricultural and horticultural insecticide comprising the compound or a salt thereof as an active ingredient; and a method for using the insecticide.
US11208404B2	Compounds useful as inhibitors of ALCAT 1 Inhibitors of ALCAT1 are described having the general formula: (I). These compounds offer a treatment for aging and age-related diseases.
US11208394B2	Chemical process to manufacture branched-caprolactone Synthesizing an alkyl-caprolactone includes hydrogenating an alkyl-phenol to yield a first mixture comprising an alkyl-cyclohexanone and an alkyl-cyclohexanol; separating the alkyl-cyclohexanone from the first mixture to yield a first portion of a purified alkyl-cyclohexanone; oxidizing the first portion of the purified alkyl-cyclohexanone to yield a second mixture comprising an alkyl-caprolactone, the alkyl-cyclohexanone, and the alkyl-cyclohexanol; separating the alkyl-caprolactone from the second mixture to yield a third mixture comprising the alkyl-cyclohexanone and the alkyl-cyclohexanol; combining the third mixture and the first mixture in to yield a fourth mixture; separating the alkyl-cyclohexanone from the fourth mixture to yield a second portion of the purified alkyl-cyclohexanone; oxidizing the second portion of the purified alkyl-cyclohexanone to yield a fifth mixture comprising the alkyl-caprolactone, the alkyl-cyclohexanone, and the alkyl-cyclohexanol; separating the alkyl-caprolactone from the fifth mixture; and combining the alkyl-caprolactone from the fifth mixture with the alkyl-caprolactone from the second mixture.
US11208393B2	Methods for extraction, processing, and purification of a selected family of target compounds from cannabis Disclosed are methods for separating, recovering, and purifying tetrahydrocannabinolic acid (THCA) salts from an organic solvent solution comprising a mixture of cannabinoids. The methods comprise solubilizing the mixture of cannabinoids in a selected C5-C7 hydrocarbon solvent, adding thereto a selected amine to thereby precipitate a THCA-amine salt therefrom, dissolving the recovered THCA-amine salt in a selected solvent and then adding thereto a selected antisolvent to thereby recrystallize a purified THCA-amine salt therefrom. The recrystallized THCA-amine salt may be decarboxylated to form a mixture of Δ9-tetrahydrocannabinol (Δ9-THC) and amine. The Δ9-THC amine mixture may be acidified to separate the amine from Δ9-THC. The recovered Δ9-THC may be concentrated to produce a highly purified Δ9-THC. Also disclosed are THCA-amine salts produced with amines selected from groups of diamines, amino alcohols, and tertiary amines.
US11208392B2	N-alkyl-D-glucaro-6 amide derivatives and alkylammonium salts thereof as intermediates for preparing D-glucaro-6,3-lactone monoamide Provided herein is a process for preparing D-glucaro-6,3-lactone monoamide from D-glucaro-6,3-lactone.
US11208384B2	Sulfinylpyridines and their use in the treatment of cancer There is provided compounds of formula I (I) or pharmaceutically-acceptable salts thereof, wherein L, R1, R2, R3, R4 and n have meanings provided in the description, which compounds are useful in the treatment of cancers.
US11208383B2	KCNQ potentiators Small molecule potentiatiors to potassium channels (such as Kv7 potentiators—which are also called KCNQ potentiators), compositions including such compounds, and methods of using such compounds for the treatment of Amyotrophic Lateral Sclerosis and other neurological diseases caused by changes in motor neuron excitability, including, but not limited to, primary lateral sclerosis, pseudobulbar palsy, progressive bulbar palsy, progressive muscular atrophy and epilepsy.
US11208378B2	Alkoxymethyl-substituted bisphenol compound The present invention addresses the problem of providing a novel alkoxymethyl-substituted bisphenol compound having exceptional storage stability and exceptional solvent solubility, heat resistance, and optical properties when used as a resin raw material. This problem can be solved by using an alkoxymethyl-substituted bisphenol compound represented by General Formula (1): (wherein each R independently represents an alkyl group having 1 to 4 carbon atoms).
US11208375B2	Process for making solid methylglycine diacetate (MGDA) alkali metal salt, and solid particles Process for making solid methylglycine diacetate (MGDA) alkali metal salt (a), said process comprising the steps of (A) providing a 35 to 60% by weight aqueous solution of said MGDA salt having a temperature in the range of from 50 to 90° C., (B) adding 0.01 to 2% by weight of a particulate solid with a pore volume in the range of from 0.25 to 0.75 cm3/g, determined by nitrogen adsorption in accordance with 66134:1998-02 (b), the percentage referring to the content of (a), (C) crystallizing (a), (D) removing said crystalline (a) from the mother liquor.
US11208372B2	Hydroxy carboxylic acid esters, manufacturing process thereof and use thereof Disclosed are compounds of formula (I) (R1OOC)a—R2(OH)c—COO—(CnH2n—O)m—OC—R3(OH)d—(COOR4)b (I) wherein R1 and R4 independently of one another are hydrogen, a metal cation, an ammonium cation, C1-C6-alkyl, cycloalkyl with three to nine ring carbon atoms, aryl with five to ten ring carbon atoms, aryl that is substituted with one or two alkyl groups, aryl that is connected via an alkylene group with the carboxyl group, —(CnH2n—O)m—H or —O—R2(COOR1)a+1, R2 and R3 independently of one another are aliphatic hydrocarbon residues with one to eight carbon atoms, a and b independently of one another are integers from 1 to 4, c is an integer from 0 to 4, d is an integer from 1 to 4, n is 2, 3 or 4, and m is 1, 2, 3 or 4, with the proviso that R1 and R4 may be different within a molecule within the given definitions. These compounds are characterized by a very good complexation power for metal cations and can be used in detergents and cleaning agents, in oil extraction and for water softening.
US11208369B2	Hydroformylated triglycerides and uses thereof This disclosure provides methods for the chemical modification of triglycerides that are highly enriched in specific fatty acids and subsequent use thereof for producing functionally versatile polymers.
US11208367B2	Production method for p-xylene A method for producing p-xylene, comprising: a dimerization step of bringing a first raw material comprising isobutene into contact with a dimerization catalyst to generate C8 components comprising diisobutylene; a cyclization step of bringing a second raw material comprising the C8 components into contact with a dehydrogenation catalyst comprising Pt in the presence of water to obtain a reaction product comprising p-xylene; and a collection step of collecting p-xylene from the reaction product.
US11208365B2	Processes and apparatuses for methylation of aromatics in an aromatics complex Processes and apparatuses for benzene and/or toluene methylation under conditions of low temperatures in one of a vapor phase, a liquid phase or a mixed vapor-liquid phase, in an aromatics complex for producing para-xylene are described. More specifically, a process for producing a xylene isomer comprising reacting oxygenates with an aromatic feedstock comprising toluene and/or benzene in a methylation zone operating under alkylation conditions including one of a vapor, a liquid phase or a mixed vapor-liquid phase in the presence of a catalyst to provide a product stream comprising the xylene isomer is described.
US11208364B2	Oxidative coupling of methane implementations for olefin production The present disclosure provides oxidative coupling of methane (OCM) systems for small scale and world scale production of olefins. An OCM system may comprise an OCM subsystem that generates a product stream comprising C2+ compounds and non-C2+ impurities from methane and an oxidizing agent. At least one separations subsystem downstream of, and fluidically coupled to, the OCM subsystem can be used to separate the non-C2+ impurities from the C2+ compounds. A methanation subsystem downstream and fluidically coupled to the OCM subsystem can be used to react H2 with CO and/or CO2 in the non-C2+ impurities to generate methane, which can be recycled to the OCM subsystem. The OCM system can be integrated in a non-OCM system, such as a natural gas liquids system or an existing ethylene cracker.
US11208358B2	Cubic boron nitride sintered body and cutting tool including the same Provided is a cubic boron nitride sintered body including more than or equal to 85 volume percent and less than 100 volume percent of cubic boron nitride particles, and a remainder of a binder, wherein the binder contains WC, Co, and an Al compound, the binder contains W2Co21B6, and, when IA represents an X-ray diffraction intensity of a (111) plane of the cubic boron nitride particles, IB represents an X-ray diffraction intensity of a (100) plane of the WC, and IC represents an X-ray diffraction intensity of a (420) plane of the W2Co21B6, a ratio IC/IA of the IC to the IA is more than 0 and less than 0.10, and a ratio IC/IB of the IC to the IB is more than 0 and less than 0.40.
US11208356B2	Golden ceramic, method for preparing same and ceramic housing A golden ceramic includes: a ceramic matrix in a weight percentage of 80-99% and a colorant in a weight percentage of 1-20%, wherein the ceramic matrix includes zirconium oxide and yttrium oxide, and the colorant includes zirconium nitride.
US11208355B2	Metal oxide ceramic nanomaterials and methods of making and using same Provided are metal oxide ceramic materials and intermediate materials thereof (e.g., nanozirconia gels, nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental articles). The nanozirconia gels are formable gels. Also provided are methods of making and using the metal oxide materials and intermediate materials. The nanozirconia gels can be made using, for example, osmotic processing. The nanozirconia gels can be used to make nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental article. The nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental articles have desirable properties (e.g., optical properties and mechanical properties).
US11208352B1	Lithium-treated calcium aluminate cement (CAC)-based products, concretes, and related techniques Lithium-treated calcium aluminate cement (CAC)-based products, concretes, and related techniques are disclosed. In accordance with some embodiments, a lithium-treated CAC mixture may be produced by intergrinding ground-down CAC, class C fly ash, a lithium compound, and a polycarboxylate material. In accordance with some embodiments, a cementitious material may be produced by intergrinding said lithium-treated CAC mixture with class C fly ash, sodium citrate, and a polycarboxylate material. In accordance with some embodiments, a concrete may be produced by mixing said cementitious material (including said lithium-treated CAC mixture) with rock, sand, and water.
US11208346B2	Processes of making glass with textured surface and 3-D shape A process for forming a textured 3-D glass-based substrate includes texturing a first surface of a glass-based substrate and shaping the glass-based substrate into a three-dimensional shape. The surface profile of the substrate is non-planar. In some embodiments, texturing the first surface of the glass-based substrate provides the first surface with an average roughness of 10 nm to 2000 nm.
US11208344B2	Textured glass articles and methods of making the same A textured glass article that includes: a glass substrate comprising a thickness, a primary surface and a bulk composition at the midpoint of the thickness; and a textured region defined by the primary surface and comprising a textured region composition. The textured region comprises a sparkle of 2% or less. Further, the bulk composition comprises about 40 mol % to 80 mol % silica and the textured region composition comprises at least about 40 mol % silica.
US11208341B2	Sewage treatment device and method for synchronously recovering water and electric energy Provided is a sewage treatment device and method for synchronously recovering water and electric energy, belonging to the field of sewage treatment. The method includes the following steps: providing municipal sewage serving as influent water and a sludge and sewage mixed solution serving as a feed solution to enter a feed solution channel of a membrane component through a peristaltic pump, and allowing brine serving as a draw solution to enter a draw solution channel of the membrane component through a high pressure pump; allowing water to flow from the side of the feed solution to the side of the draw solution by means of the osmotic pressure difference between two sides of an FO membrane, and allowing the mixed draw solution with high pressure to push a turbine to rotate in an outflow process, so as to generate electric energy; and allowing the diluted draw solution to pass through a draw solution recovery system to obtain recycled water, and at the same time, allowing the concentrated draw solution to continue to be applied to the FO membrane.
US11208340B2	Multi-step method for producing algae products A multi-step method for producing an algae product comprising, a microorganism consumption step, another step, and an algae product collection step. The microorganism consumption step comprises, combining a liquid growth medium comprising microorganisms with a phagotrophic algae capable of producing a desired algae product, consuming said microorganisms by said phagotrophic algae, and growing said phagotrophic algae. Another step comprises either a microorganism growth step or a photosynthetic algal growth step. A microorganism growth step comprises providing a liquid growth medium comprising nutrients and microorganisms capable of said consuming said nutrients, consuming said nutrients by said microorganisms, and growing said microorganisms. A photosynthetic algal growth step comprises providing a substantially organic nutrient depleted liquid medium, providing a microorganism population comprising said phagotrophic algae, photosynthetic growth of said phagotrophic algae. An algae product collection step comprises collecting a desired algae product from said phagotrophic algae.
US11208336B2	Fully regenerative distillation system for low-cost water desalination A desalination device includes a sealed desalination chamber with two compartments, an evaporator space that contains saline water, and a condenser space that contains fresh water, a saline water distribution mechanism that directs the saline water into the evaporator space, a vapor compressor that directs a stream of pressurized freshwater vapor into the condenser space, and an integrated regenerative boundary between the evaporator space and the condenser space that has two sides, an evaporation surface and a condensation surface, enabling the pressurized freshwater vapor to condense on the condensation surface to generate freshwater, and where the latent heat of the condensation process transfers across the integrated regenerative boundary into the evaporator space and evaporates a portion of the saline water to produce freshwater vapor.
US11208335B1	Piston valve with annular passages An exemplary valve control system includes a master controller that wirelessly communicates with a plurality of slave controllers. The slave controllers are each associated with respective devices and sensors. In exemplary arrangements a valve slave controller is associated with a motor that controls a condition of a valve. An exemplary control valve includes a valve body with a plurality of ports (A, B, C, D, E, F) and a plurality of annular flow passages. A piston is selectively movable within a bore within the valve body through operation of the motor and valve slave controller. The valve slave controller is selectively operative to control the position of the piston so as to selectively enable liquid flow through the valve.
US11208331B2	Hydrous silica for rubber-reinforcing filler The present invention pertains to a hydrous silica for rubber-reinforcing filler, having a BET specific surface area ranging from 230 to 350 m2/g, and satisfies the following: a) the pore volume of 1.9 nm to 100 nm pore radius measured by the mercury press-in method (VHP-Hg) ranges from 1.40 to 2.00 cm3/g; b) total pore volume in the range of 1.6 nm to 100 nm pore radius by the nitrogen adsorption/desorption method (VN2) ranges from 1.60 to 2.20 cm3/g; and c) the pore volume ratio of (a) and (b) VHP-Hg/VN2 ranges from 0.70 to 0.95. This invention provides a hydrous silica capable of further improving reinforcing properties of a rubber, particularly the wear resistance by improving dispersibility of the hydrous silica in the rubber in addition to rubber reinforcing properties obtained by a high BET specific surface area.
US11208330B2	Identification and optimization of carbon radicals on hydrated graphene oxide for ubiquitous antibacterial coatings In various embodiments functionalized graphene oxide(s) are provided that demonstrate improved antimicrobial activity, where the graphene oxide(s) are functionalized to increase carbon radical (.C) density.
US11208328B2	Method for carbon nanotube purification A method for carbon nanotube purification, preferably including: providing carbon nanotubes; depositing a mask; and/or selectively removing a portion of the mask; and optionally including removing a subset of the carbon nanotubes and/or removing the remaining mask.
US11208327B2	Process for the large-scale manufacture of zeolite-templated carbon A method for the large-scale synthesis of a zeolite-templated carbon (ZTC). The method includes the steps of: introducing a bed material comprising a zeolite to a fluidized bed reactor and heating the bed material to a temperature between 550° C. and 800° C.; fluidizing the bed material with a fluidizing gas and maintaining the temperature of the bed material between 550° C. and 800° C.; introducing an organic carbon precursor while fluidizing the zeolite for a period of time such that carbon is deposited on the zeolite by chemical vapor deposition to produce a zeolite-carbon composite; and treating the zeolite-carbon composite with an acid solution such that the zeolite template is dissolved and the ZTC is obtained.
US11208326B1	Method and apparatus for manufacturing nitrogen tetroxide Dinitrogen tetroxide (N2O4) is synthesized in an apparatus by the reaction of concentrated nitric acid with copper. Oxygen is applied as a carrier gas to convert NO to NO2, and water vapor is removed with a tube dryer. A molecular sieve is applied to reduce and remove impurities.
US11208324B2	Polycrystalline cubic boron nitride and method for manufacturing the same A polycrystalline cubic boron nitride comprising 98.5% by volume or more of cubic boron nitride, wherein the cubic boron nitride has a dislocation density of more than 8×1015/m2, the polycrystalline cubic boron nitride comprises a plurality of crystal grains, and the plurality of crystal grains have a median diameter d50 of an equivalent circle diameter of 0.1 μm or more and 0.5 μm or less.
US11208322B2	Solar fuel generator including a catalytic mesh This disclosure provides systems, methods, and apparatus related to a solar fuel generator. In one aspect, a device includes a photovoltaic cell, the photovoltaic cell having a first surface and a second surface, a mesh disposed on the first surface of the photovoltaic cell, and a polymer disposed on the mesh and on the first surface of the photovoltaic cell. The mesh has a catalyst disposed thereon. The polymer covers the first surface of the photovoltaic cell, with at least a portion of the mesh not being covered with the polymer.
US11208319B2	Method for manufacturing a MEMS unit for a micromechanical pressure sensor A method for manufacturing a MEMS unit for a micromechanical pressure sensor. The method includes the steps: providing a MEMS wafer including a silicon substrate and a first cavity formed therein, under a sensor membrane; applying a layered protective element on the MEMS water; and exposing a sensor core from the back side, a second cavity being formed between the sensor core and the surface of the silicon substrate, and the second cavity being formed with the aid of an etching process which is carried out with the aid of etching parameters changed in a defined manner; and removing the layered protective element.
US11208316B2	Semi-automated beverage dispensing machines and methods Food product dispensing machines and methods for dispensing food product into a cup. The food product dispensing machine includes a cup holder having a target element, a sensor that senses the target element, and a controller. The cup holder is configured to hold a cup such that the cup prevents the sensor from sensing at least a portion of the target element. The controller determines whether a cup is present in the cup holder and/or a size of the cup based on a remaining portion of the target element that is sensed by the sensor when the cup is held by the cup holder. Drive mechanisms are configured to move the first and second cup holders along first and second radial paths, respectively, with respect to the common dispensing position. An indicator is configured to indicate a remaining number of cup dispenses to the user.
US11208314B2	Pressurized beverage concentrates and appliances and methods for producing beverages therefrom The present invention describes methods and devices in which concentrated beverage products, each packaged in a pressurized container, can be combined with liquids and/or other ingredients to produce one or more servings of a beverage. These products provide users with a convenient way to prepare both alcoholic and non-alcoholic beverages (including carbonated beverages) in various serving sizes and quantities by combining the pressurized beverage concentrate with (possibly carbonated) liquids and other ingredients.
US11208312B2	Machine and method for packaging pourable food products The present invention relates to a packaging method for packaging a pourable product in at least one container, by means of which it is obtained an improvement in the flexibility of the packaging machine configured for carrying out the method with regards to the type of the product which is to be packaged, and to a machine configured for carrying out the method.
US11208310B2	Fluid filling systems and methods The present disclosure provides systems and methods for refilling fluid containers. A fluid container may include a bottle and a valve assembly. The valve assembly may include two valves and be configured to engage with the bottle and a filling head or dispensing head. A system is configured to provide pressurized fluid to the refillable container, monitor filling, determine when to stop filling, and determine how much fluid was provided. The valve assembly may include a float mechanism coupled to one of the valves of the valve assembly to ensure fluid flow is stopped when the fluid container is full. The fluid, which can include carbon dioxide, is stored in a storage tank. A flow system provides the fluid to a filling head, which engages with the fluid container. The flow system includes a transfer pump, valves, and sensors configured to provide the fluid to the filling head.
US11208308B1	Load stabilization device An extension system for a bucket tractor includes a boom and a scaffold removably secured to a base configured to be supported with a bucket of a tractor.
US11208306B2	Cable block A cable block including a frame having an upper section and a lower section together defining an inner opening. The lower section has a main sheave rotatably connected thereto, with a section of the main sheave defining a lower portion of the inner opening. The upper section is hingedly connected to the lower section at a pivot point, with a lever extending on an opposite side of the pivot point than the remaining of the upper section. The lever is configured to extend into the inner opening and be engageable with the support cable, when the cable block is configured in the open configuration, and to drive the upper section in rotation upon a force being exerted on the lever by the support cable, to move the cable block from an open configuration to a closed configuration.
US11208304B2	Limited rotation slewing ring crane A limited rotation slewing ring crane may include a pedestal, a column rotatively coupled, about a first rotation axis, to the pedestal by a slewing ring rotative coupling, and stops for limiting the relative rotation of the column with respect to the pedestal. The crane may also include a rotative sensor adapted to measure a rotation angle of the column with respect to the pedestal. The rotation sensor may include a tubular body axially extending from the base of the column, a stationary body connected to the pedestal and a wheel. A second rotation axis of the wheel may be offset with respect to a first rotation axis of the column with respect to the pedestal.
US11208297B2	Power switch device for an oiler of an escalator or a moving walk The present disclosure relates to a power switch device for an oiler of an escalator or a moving walk. The power switch device includes: a power input port, including a first power input terminal and a second power input terminal; a power output port, including a first power output terminal and a second power output terminal, the second power input terminal being connected to the second power output terminal, and a first circuit branch and a second circuit branch connected in parallel being connected between the first power input terminal and the first power output terminal; an electronically controlled on-off apparatus, connected in the first circuit branch; a manual switch, connected in the second circuit branch; and a state indicator, used to indicate a switching state of the manual switch.
US11208292B2	Folding roller and machine comprising said roller The folding roller includes a rotation axis and at least a gripping member extending longitudinally along the folding roller, controlled by at least a piezoelectric actuator. The piezoelectric actuator causes a pivoting movement of the gripping member about its pivoting axis parallel to the rotation axis of the folding roller.
US11208291B2	Post-processing apparatus and image forming apparatus system A post-processing apparatus includes a post-processing unit configured to receive sheets from an image forming apparatus, perform processing on the received sheets, and then discharge the processed sheets through a discharge port. A sensor is configured to detect a presence of an object at the discharge port. The sensor includes a first light emitter on a first side of the discharge port that is positioned to emit a light across a width of the discharge port, a reflector on a second side of the discharge port opposite the first side in a first direction, and a first light receiver positioned to receive light of the first light emitter from the reflector. A controller is configured to terminate the processing on the received sheets by the post-processing unit when the sensor detects the presence of the object at the discharge port.
US11208290B2	Post-processing apparatus, image forming apparatus, and post-processing method Provided are a post-processing apparatus, an image forming apparatus, and a post-processing method capable of avoiding the occurrence of a malfunction due to a failure to discharge a sheet bundle after a binding process. A plurality of sheets is loaded on a stack tray. A staple unit binds the plurality of sheets. A discharge roller discharges the sheet bundle bound by the staple unit from the stack tray. Each time a sheet is conveyed to the stack tray, an aligning unit moves between a first position in contact with the sheet loaded on the stack tray and a second position separating from the sheet. A detection processing unit detects a failure of discharging the sheet bundle by the discharging roller. A stop processing unit can stop the operation of the aligning unit when the discharge failure is detected by the detection processing unit.
US11208283B2	Receiving means for receiving film material The invention relates to a receiving means (200) for receiving film material (250) for use in a winding machine (IO), wherein the receiving means (200) comprises at least one bearing region (210) for attaching the receiving means (200) to a winding unit (20) of the winding machine (IO) and comprises a wall (220) having an outer surface region (230), wherein the wall (220) is designed in such a way that the surface region (230) can be placed onto a transport device (30) of the winding machine (10) and the film material (250) can be received onto the surface region (230).
US11208282B2	Method of initiating a web winding process in a web winding system A system has first and second winding drums and a core feeder for inserting a core into a winding nest for forming a convoluted roll. The leading edge of the web is engaged with a threading belt and directed around the first winding drum and through the winding nest to a position where the leading edge is beyond where the core feeder inserts the core into the winding nest thus providing an excess portion of the web between the leading edge and the core feeder core insertion position. A thread-up core is inserted into the winding nest and rotated with the winding drums so that the excess portion moves around the thread-up core. The leading edge is separated from the threading belt, the excess portion of the web is wound around the thread-up core, and the web from the supply is wound around the thread-up core.
US11208280B2	Tape holder Implementations of a tape holder are provided. In some implementations, the tape holder may be used to secure a roll of tape to a magnetic surface. In some implementations, the tape holder is comprised of a base member and a spool support.
US11208279B2	Medium conveying apparatus for correcting a skew of a medium using three sensors A medium conveying apparatus includes a plurality of feed rollers, each feed roller rotating independently at a respective speed to feed a medium, a first sensor located on a downstream side of the plurality of feed rollers in a medium conveying direction and also in a central part in a direction perpendicular to the medium conveying direction, to detect the medium, a second sensor and a third sensor located on both sides of the first sensor in the direction perpendicular to the medium conveying direction, to respectively detect the medium, and a processor to change the speed of one of the plurality of feed rollers at least until the first sensor detects the medium when any of the second sensor or the third sensor detects the medium and the first sensor does not detect the medium within a predetermined time.
US11208273B2	Method and device for transportation A device and a plurality of methods for transporting are disclosed. One method includes moving a plurality of transport movement devices (14) along a guide track (22) by use of a linear motor system. A long stator (16) of the linear motor system has, along a portion of the guide track (22), a predetermined functional region. The method includes portion-wise varying of a magnetic field generation of the long stator (16) within the predetermined functional region (46) for successive transport movement devices of the plurality of transport movement devices (14). It is thus possible to achieve various advantages, such as for example prolonging the motor service life, preventing emergency shut-offs, increased performance of the long stator linear motor and/or allowing smaller dimensioning of the long stator (16).
US11208272B2	Automated item sortation and container handling systems Systems, methods, and computer-readable media are disclosed for automated item sortation and container handling. In one embodiment, an example method may include determining, by a controller, a first item identifier of a first item at an induction portion of a sortation system, determining an order identifier associated with the first item identifier, and determining a first container associated with the order identifier. The method may include causing a first mobile carrier unit to receive the item, and causing the first mobile carrier unit to deliver the first item to the first container.
US11208271B2	Quick change transfer assembly A quick-change vacuum starwheel assembly including at least one of a quick-change height adjustment assembly or a quick-change vacuum starwheel mounting assembly.
US11208270B1	Systems and methods for scanning and dimensioning items in motion Systems, methods, and computer-readable media are disclosed for scanning and dimensioning items in motion. In one embodiment, an example system may include a first camera oriented along a vertical axis towards a gap between a first surface and a second surface, a first light emitting array positioned to emit light towards the gap, and a first light receiving array aligned with the light emitting array and configured to detect the light. The first light emitting array and the first light receiving array may be offset from the vertical axis, and the system may be configured to determine a first dimension of an item passing over the gap using the first light emitting array and the first light receiving array.
US11208269B2	Abnormality detecting system, abnormality detecting apparatus, abnormality detecting method, computer program, and chain Provided are an abnormality detection system, an abnormality detection device, an abnormality detection method, a computer program, and a chain that enable detecting of an abnormality not only in a chain but also in equipment using the chain while distinguishing the location at which the abnormality occurs. The abnormality detecting system comprises a sensor unit comprising a sensor, to be fixed to a chain that is to be attached to equipment, and transmitting an output from the sensor, a detection section which detects an abnormality of the chain or the equipment based on the output, and a determining section which determines a location of the abnormality in the equipment, based on a position of a part fixed with the sensor unit in the equipment, the position changes in each time point with moving of the chain.
US11208267B2	Launching system for robotic sausage loading machine A system, and associated method, for launching and delivering separated food product in organized groups to a robotized packaging station for the product. The system initiates the delivery via a metered hopper of food product delivering the product to a launch V-belt that aligns the product end to end. A successive singulator belt, positioned adjacent to and receiving product from the launch belt, further organizes the product into a single file alignment. An optional separator belt may follow the singulator belt to create gaps between successive product units. The product is then delivered to a pick belt for product to be provided to the packaging robot. The system product information is from a single (per product delivery line) sensor, enabling intergrated end-to-end control from hopper to robot, and a nearly continuous motion of said pick belt.
US11208264B2	System for storing and transporting objects stored in racks of a warehouse A storage and transport system in a warehouse for an object intended to be stored in a rack of the warehouse. The system includes: a bin suitable for accommodating the object; and a powered trolley capable of climbing along the rack including a device for gripping and removing the bin. The gripping and removal device includes a support mounted so as to be movable relative to the chassis of the trolley between: an extended position, in which the support extends at least partially on a lateral edge of the carriage out of alignment with the chassis; and a retracted position, in which the support is housed opposite the chassis. The support includes a structural element and a protruding finger fixed with respect to the structural element and facing upward. The bottom of the bin has a fingerprint configured to accommodate a portion of the finger.
US11208262B2	Refuse container engagement A refuse collection vehicle includes a grabber that is operable to engage a refuse container, at least one sensor that is arranged to collect data indicating a relative positioning of a first arm of the grabber and a second arm of the grabber, and a controller having one or more control elements for selecting a target positioning of a first arm of the grabber and a second arm of the grabber. The first arm and the second arm automatically move to the target positioning in response to a signal received by an onboard computing device of the vehicle.
US11208251B2	Valve for a flexible packaging with an aerating and/or venting opening and method for aerating and/or venting a flexible packaging The invention relates to a valve (4) for a flexible packaging (1), comprising a valve housing (11) to be connected to an aerating and/or venting opening (6) of the packaging and having a first opening (22) and an opposite second opening (35), and a flexible membrane (24) movable between a position which closes the first opening and a position which leaves the first opening clear. The valve is provided with guide means (28) for guiding the movement of the membrane, wherein there is space (40) in the housing adjacently of the membrane for the purpose of forming a passage between the first and second opening when the membrane takes up-its open position. The invention also relates to a flexible packaging with an aerating and/or venting opening and a valve arranged therein. The invention further relates to an assembly of an aerating and/or venting device and such a valve. The invention also relates to a method for evacuating a flexible packaging via a venting opening while making use of such a valve and a venting device connected thereto. The invention finally relates to a method for flushing a flexible packaging with gas via an aerating and/or venting opening by making use of such a valve and an aerating and/or venting device connected thereto.
US11208248B2	Container for smoking articles A container for smoking articles has an outer housing including a hinged lid rotatable between open and closed positions. An inner package has an access opening through which smoking articles can be removed. The access opening can be covered by a reclosable flap when the hinged lid is in the closed position. With the lid in the closed position, the reclosable flap forms an overlap region with a surface of the inner package that extends around the periphery of the access opening. The overlap region includes a first adhering region to releasably affix the surface of the inner package and the reclosable flap, and a first non-adhering region. The first non-adhering region includes a portion of the periphery of the access opening.
US11208245B2	Packaging, barrier packaging material, and packaging bag A packaging is provided including: a base layer including at least one layer of a biaxially oriented resin film; and a sealant layer including at least a first thermoplastic resin layer and a second thermoplastic resin layer, in which the base layer, the first thermoplastic resin laser, and the second thermoplastic resin layer are laminated in this order, a density of a first resin forming the first thermoplastic resin layer is higher than a density of a second resin forming the second thermoplastic resin layer, the density of the first resin is 0.90 g/cm3 or higher, the density of the second resin is 0.92 g/cm3 or lower, and the second thermoplastic resin layer contains 200 to 2000 ppm of a lubricant including at least one of a fatly acid amide lubricant and a fatty acid ester lubricant.
US11208243B2	Closure capsule A closure capsule for closing a container, comprising: —a stopper (2) applicable to the container and comprising a first perforable membrane (21); —a first cutter (31) of the first membrane, said first cutter (31) being movable between a start stroke position and an end stroke position; in the start stroke position of the first cutter (31), in combination with at least the first membrane (21), the first cutter (31) delimits a first tank (41) for containing a first substance; in the end stroke position of the first cutter (31) at least a part of the first membrane (21) being perforated to enable passage of the first substance from the first tank (41) to the container. The stopper (2) comprises at least a second perforable membrane (22). The capsule (1) comprises a second cutter (32) for cutting the second membrane, said second cutter (32) being movable between a start stroke position and an end stroke position; in the start stroke position of the second cutter (32), in combination with at least the second membrane (22), the second cutter (32) delimiting a second tank (42) for containing a second substance; in the end stroke position of the second cutter (32) at least a part of the second membrane (22) being perforated and enabling passage of the second substance from the second tank (42) to the container.
US11208241B1	Dispensing cap A child resistant dispensing cap including an inner cover and an outer ring. The inner cover being coaxially nested and retained within the outer ring. The outer ring configured to rotate around the inner cover. The inner cover and the outer ring may be manipulated relative to each other to be in a number of different configurations, including a locked position, an unlocked position and an open position. The inner cover including a lid pivotably mounted to the inner cover from a closed position to an open position. The lid including a free end. The outer ring including a front tab capable of flexing radially inward towards the inner cover. The dispensing cap configured in the unlocked position capable of flipping up the lid when the free end of the lid aligns with the front tab of the outer ring. When the front tab is pushed radially inward, an underside surface at the free end of the lid is exposed to allow the lid to pivot to the open position.
US11208240B2	Filling system for electronic smoking devices A filling system for an electronic cigarette (10) is disclosed in which a nozzle (38) of a liquid dispenser (80) contains a plunger (62) which is biased by a spring (60) into a closed position in which liquid is prevented from flowing through the nozzle (38). In use the nozzle (38) is inserted into an open end (42) of a liquid reservoir (34) for an electronic cigarette containing an air tube (32). The plunger (62) engages with the end of the air tube (32) blocking the air tube (32) and opening the liquid flow path through the nozzle (38). The arrangement of the plunger (62) and nozzle (38) is such that operation of the plunger (62) only occurs when the nozzle (38) engaged within a liquid reservoir (32). A membrane (96) can be provided to prevent leakage from the liquid reservoir (34) when the nozzle (38) is disengaged.
US11208239B2	Selective flow member for a container A flow selector configured for selectively or optionally regulating flow of liquid from a container is disclosed.
US11208234B2	Drinking bottle and valve therefor A drinking bottle includes a first bottle part (10) having an interior (100) for receiving a beverage (G) and a second bottle part (11) having an interior (110) for receiving the beverage (G) and having a bottle opening (13) for dispensing the beverage (G) from the interior (110), wherein the interiors (100, 110) of the two bottle parts (10, 11) are or can be brought into fluid communication with each other. The drinking bottle (1A-1D) has at least one configuration in which the two bottle parts (10, 11) are inclined to each other. The invention also relates to a valve for a drinking bottle. In this way, a drinking bottle can be provided which allows a user to drink in a particularly comfortable position.
US11208230B2	Printing apparatus including optical sensor located at conveying region through which label passes A printing apparatus includes a casing, an optical sensor, a second light receiving portion and an adjustment part. The optical sensor includes a light emitting portion and a first light receiving portion. The optical sensor is provided at a position in the vicinity of the outlet and located within a conveying region. The conveying region is an area through which the print medium passes. The second light receiving portion is provided in the vicinity of the optical sensor and positioned outside the conveying region where external light is perceivable. The adjustment part is configured to adjust a sensitivity in the detection of the presence of the print medium by the first light receiving portion. Adjustment of the sensitivity of the first light receiving portion is performed based on an intensity of the external light received at the second light receiving portion.
US11208229B2	Label inspection system A system, method, and apparatus for inspecting a label for proper application thereof. The system includes a label application apparatus and an inspection apparatus associated with said label application apparatus. The method includes inspecting a spent carrier web for the presence of labels, or portions thereof, that did not transfer to articles being labeled.
US11208224B2	Bag clamping device for material bag filling system A bag clamping device for a material bag filling system is provided. A filling tube portion of a material bag can be blown to be in an upright state from a collapsed state through displacement and lift of an X-axis rail, a Y-axis rail and a Z-axis rail and blow of a pair of blowers. A pair of electric clamps is configured to clamp the filling tube portion. A pair of cantilevers is displaced to the bottom of a material filling device. The filling tube of the material filling device is displaced in a Z direction to enter the material bag for blowing air and filling the material. Through a conveyor belt displaced at the bottom in an X direction to carry the material bag with the filled material to a sealing device for sealing, so as to complete the packaging.
US11208220B2	Filling unit for a manufacturing machine for the production of disposable cartridges for electronic cigarettes Filling unit for a manufacturing machine for the production of disposable cartridges for electronic cigarettes; the filling unit has: a cylindrical tank which is arranged horizontally, is mounted so as to rotate in a stepwise manner around a vertical rotation axis, is delimited, at the bottom, by a base disc having a circular shape, and is delimited, on the sides, by a cylindrical side wall; a feeding duct that feeds a flow of tobacco inside the tank; a plurality of groups of seats, each of which is obtained in the base disc and is adapted to receive and contain a corresponding dose of tobacco; and a transfer device which is arranged in a fixed position and cyclically transfers the doses of tobacco contained inside the seats of a group standing still.
US11208215B2	Method for mounting an aircraft pylon A method for mounting an aircraft pylon connected to a wing includes: a step of pre-positioning first and second contact surfaces respectively provided on the wing and the pylon, a step of installing and tightening temporary connection elements, so as to keep the first and second contact surfaces clamped against one another, a step of installing and expanding at least one radially expandable element in at least one pair of first and second receptacles respectively provided on the wing and the pylon, a step of installing and tightening final connection elements connecting the pylon and the wing in the mounted state, a step of removing the radially expandable element(s) and the temporary connection elements, and of installing the remaining final connection elements and shear pin(s).
US11208213B2	Integrated aircraft fuselage and load-bearing structural base for aircraft seats A fuselage is described that includes a plurality of frames and a plurality of seat rows spaced apart according to a seat pitch. Each frame includes a lateral floor beam, and each seat row of the plurality of seat rows includes a load-bearing structural base with a plurality of legs attached to a proximal lateral floor beam and a distal lateral floor beam. Each seat row also includes a seat or bank of seats attached to the load-bearing structural base, where the seat or bank of seats includes at least one seat bottom and at least one seat back. Further, each seat row includes an interface between (i) the load-bearing structural base and (ii) the seat or bank of seats to allow for attachment and detachment of the seat or bank of seats relative to the load-bearing structural base.
US11208212B2	Contoured armcap for multi-seat occupant usage A contoured armcap for multi-seat occupant usage may include a top surface and a raised surface. The raised surface may be configured to separate the top surface into two areas. The raised surface may be offset from the top surface at a select height. The raised surface may be continuously coupled to the top surface via a set of sides. At least one side of the set of sides may be defined by a contour line. The two areas may include a first area configured to support a portion of an arm of a first seat occupant in a first aircraft seat coupled to a shared armrest including the contoured armcap. The two areas may include a second area configured to support a portion of an arm of a second seat occupant in a second aircraft seat coupled to the shared armrest including the contoured armcap.
US11208211B2	Replaceable connection modules for high use electronic device receptacles The present specification describes a replaceable connection module. The replaceable connection module includes a port to receive signals and power from a controller and at least one receptacle to provide received signals and power to a connected electronic device. The module also includes a plurality of conductors connecting the port with at least one receptacle. Control of the signals and power at the at least one receptacle is performed by the controller.
US11208209B2	UAV, method and system for cleaning a wall body A cleaning method includes controlling an unmanned aerial vehicle (UAV) to fly to a region of a wall body according to a path to be cleaned, and, in response to detecting a cleaning prohibition identifier associated with the region, recognizing the region as a cleaning prohibition region and controlling the UAV to fly over the cleaning prohibition region without cleaning the cleaning prohibition region.
US11208208B2	Systems and methods for synchronizing events in shifted temporal reference systems A system for synchronizing events has a first subsystem that detects, measures, or generates a first set of events and the first subsystem has a first clock for time-stamping each event detected, measured, or generated by the first subsystem. The system further has a second subsystem that detects, measures, or generates a second set of events and the second subsystem has a second clock not synchronized to the first clock. The second clock is for time-stamping events detected, measured, or generated by the second subsystem. The first set of events is related to the second set of events. The system further has a processor that correlates the first set of events with the second set of events to determine a value indicative of a temporal shift between a time of occurrence of the first set of events and a time of occurrence of the second set of events. Also, the processor temporally matches the first set of events to the second set of events and outputs data indicative of the matching between the first set of events to the second set of events to an output device.
US11208206B1	Aircraft for fixed pitch lift An aircraft for fixed pitch lift includes a fuselage, a plurality of flight components attached to the fuselage, wherein the plurality of flight components further comprises at least a lift propulsor component, wherein the lift propulsor component comprises a plurality of blades configured at a fixed angle of attack, and a pusher component, wherein the pusher component is configured to produce a forward thrust.
US11208205B2	System and method for rotorcraft autorotation entry assist A rotorcraft including a main rotor, flight controls connected to the main rotor the main rotor, a plurality of engines connected to the main rotor and operable to drive the main rotor, a main rotor revolutions per minute (RPM) sensor, and a monitoring system operable to determine an engine failure of the plurality of engines. The monitoring system is further operable to engage an automated autorotation entry assist process in response to at least determining the engine failure and according to the measured main rotor RPM, where the automated autorotation entry assist process comprises the monitoring system generating one or more rotor RPM related commands according to at least a target main rotor RPM and the measured main rotor RPM, where the automated autorotation entry assist process further comprises controlling the one or more flight controls according to the one or more rotor RPM related commands.
US11208200B1	Systems and methods for fly-by-wire reversionary flight control Some aspects relate to systems and methods for fly-by-wire reversionary flight control including a pilot control, a plurality of sensors configured to: sense control data associated with the pilot control, and transmit the control data, a first actuator communicative with the plurality of sensors configured to receive the control data, determine a first command datum as a function of the control data and a distributed control algorithm, and actuate a first control element according to the first command datum.
US11208198B2	Composite propeller vane or blade for aircraft integrating a conformation part A vane includes a fiber reinforcement having a three-dimensional weaving densified by a matrix, the fiber reinforcement including in a single woven part a root portion and an airfoil portion extending along a longitudinal direction between the root portion and a vane tip portion and along a transverse direction between a leading edge portion and a trailing edge portion. The airfoil portion includes first and second extrados and intrados faces. The fiber reinforcement includes a non-interlinking forming a housing inside the fiber reinforcement, a conformation part being present in the housing. The non-interlinking extends over a non-interlinked area inside the airfoil portion of the fiber reinforcement included between the root portion and the vane tip portion in the longitudinal direction and between the leading edge portion and the trailing edge portion in the transverse direction, the non-interlinking also opening outside the airfoil portion of the fiber reinforcement.
US11208196B2	Aerodynamic surface for an aircraft An aerodynamic surface for an aircraft, comprising a torsion box, a movable control surface, and a central element, the torsion box comprising a rear spar, upper and lower covers, and the movable control surface comprising a leading edge, a front spar, a hinge line, a beam having a first end and a second end, and a counterweight attached to the second end of the beam. The first end of the beam is attached to the front spar, and the second end is projected beyond at least the hinge line so that the counterweight is arranged between the upper and lower covers extending from the rear spar of the torsion box towards the movable control surface.
US11208195B2	Track over-travel arrestment mechanism for auxiliary supports A system to arrest flap over-travel employs a track extending from a flap and engaging an auxiliary support. The track has a deployment profile determining flap motion relative to the support structure during travel between an extended position and a normal retracted position. The deployment profile has a transition portion extending beyond the normal retracted position and terminating in a detent. A resiliently mounted catcher is configured to be displaced by the transition portion during over-travel of the flap beyond the normal retracted position and captured in the detent in a maximum retracted position thereby restraining the flap.
US11208194B2	Assembly for warping of an aerodynamic structure A spar assembly for an aircraft wing extends between an upper cover and a lower cover and includes linkages spaced consecutively along the length of the spar assembly, each linkage extending from an upper pivot, to a lower pivot, thereby joining upper and lower attachment structures of the spar assembly together. Each linkage includes a pair of fixed-length links pivotably connected at one end about a center pivot and pivotably connected at respective other ends. The spar assembly includes a drive bar connected to the center pivot of each of the linkages, and an actuator arranged to move the drive bar along the length of the spar assembly. When the actuator moves the drive bar along the length of the spar structure, the links in each pair of links are rotated relative to each other about the center pivot, thereby moving the upper and lower covers and warping the wing.
US11208191B2	Flight termination system for tethered aerial vehicles Aspects of the disclosure relate to flight termination systems for tethered aerial vehicles having envelopes. For instance, a flight termination system may include a wire heating element arranged in a loop around the balloon envelope and connected to a strain relief connector, the strain relief connector, and an electrical cable connected to the strain relief connector. The electrical cable is configured to provide current to the wire in order to melt envelope material of the envelope and terminate a flight of the aerial vehicle.
US11208189B2	Outboard motor and marine vessel An outboard motor includes an engine, a propeller shaft that rotates together with a propeller and extends in a forward-rearward direction, and a lower case that houses the propeller shaft. The lower case includes a front case and a rear case separate from the front case and positioned rearward of the front case, and the front case and the rear case are assembled to each other.
US11208185B2	Snorkeling breathing apparatus A snorkeling breathing apparatus includes a mask, a first breathing tube assembly and a one-way exhaust valve. The mask includes an outer mask and a breathing mask arranged in the outer mask, the mask is equipped with a breathing chamber. The breathing tube assembly includes a first breathing tube and a one-way inhaling valve. The breathing tube is connected to the breathing mask through the inhaling valve. The exhaust valve is connected and mounted on the outer mask and the breathing mask. While inhaling, the inhaling valve conducts and air enters the chamber through the breathing tube. While exhaling, the exhaust valve conducts and air flows from the chamber to outside.
US11208183B2	EPIRB having retention carriage strap for hands free carriage An emergency position indicating radio beacon that includes a waterproof rigid housing, antenna, a retention carriage strap securely mounted around its exterior periphery on a spool in a storage position. In an emergency the user can unwind the retention carriage strap and form an adjustable loop in the strap using hook and loop fasteners to firmly attach the strap connected to the EPIRB housing to the user's arm that allows a user to transport the radio beacon with the retention carriage strap in a hands-free configuration.
US11208179B2	Maintenance facility, power generation facility, and maintenance method for device A maintenance facility includes: a first barge; a first connection portion disposed on the first barge and configured to connect the first barge to a second barge mounted with a device including a maintenance target portion; and a building disposed on the first barge and including a wall portion and a roof portion. On the first barge, a temporary placing space in which the maintenance target portion can be placed is disposed between the first connection portion and the building.
US11208175B2	Continuously variable transmission for a bicycle The present invention relates to a continuously variable transmission (1000, 8000) for a bicycle comprising: input means (1100, 2100, 3100), output means (1300, 2300, 3300, 4300, 300, 6300), and transmission means (1200) connecting the input means to the output means, wherein the output means comprise output controlling means (1340, 2340, 3340, 4340, 5340, 6340) controlling a gear ratio of the output means, wherein the continuously variable transmission is a V-belt type continuously variable trans mission.
US11208174B2	Bicycle operating device A bicycle operating device comprises a base member, an operating member, a wireless communicator, and a power supply. The base member includes a first end to be mounted to a bicycle handlebar and a second end opposite to the first end. The operating member is pivotally coupled to the base member about a first pivot axis. The electrical switch is to be activated by an input operation from a user. The wireless communicator is electrically connected to the electrical switch to wirelessly transmit a signal to an additional component in response to the input operation. The power supply is electrically connected to the wireless communicator to supply electrical power to the wireless communicator. The wireless communicator and the power supply are at least partially overlap with each other when viewed from a direction perpendicular to the first pivot axis.
US11208172B2	Suspension pivot assemblies having a retention feature A pivot assembly for a cycle linkage suspension is provided that includes first and second members and a pivot. The first and second members include lateral openings extending therethrough and the pivot includes a rod portion that is configured to be disposed within the lateral openings to pivotably couple the first and second members together. The rod portion further includes an opening that extends through an intermediate portion thereof. The pivot assembly can further include a pin configured to be removably inserted at least partially into the opening in the rod portion to thereby restrict lateral movement of the rod portion within the first and second members.
US11208166B2	Device for positioning vehicle parts A device for positioning motor vehicle parts in the production or manufacture of motor vehicles. The device includes a main frame, at least one main module configured to be disposed on the main frame, at least one interchangeable first docking plate configured for releasable connection to the main module, and a plurality of first receptacles, arranged on the interchangeable first docking plate, configured to hold the motor vehicle parts at a predefined position during the production.
US11208164B2	Spalling resistant track link and roller interface A track link rail surface and roller interface includes a first roller including a cylindrical configuration defining a radial direction, a longitudinal axis, a circumferential direction, and a plane containing the radial direction and the longitudinal axis. The first roller includes a first track link rail engaging surface including a first concave arcuate surface defining a first concave radius of curvature. The interface includes a first track link including a first track link rail surface including a first convex arcuate surface defining a first convex radius of curvature that is less or equal to the first concave radius of curvature.
US11208161B2	Vehicle system In a vehicle system, a driver information acquisition unit acquires information about a driver of a vehicle. A detection unit detects that there is a possibility that the vehicle has been damaged. An identification unit identifies a driver of the vehicle when it is detected that there is a possibility that the vehicle has been damaged, based on the acquired driver information.
US11208157B2	Tailgate assembly with cargo bed access opening and method of providing access to a cargo bed of a vehicle A tailgate assembly according to an exemplary aspect of the present disclosure includes, among other things, a primary tailgate having a cargo bed access opening. The primary tailgate moveable between a closed position and a fully open position relative to a cargo bed of a vehicle. The tailgate assembly further including a secondary tailgate that can move between a blocking position where the secondary tailgate extends into the cargo bed access opening and an accessing position where the secondary tailgate is retracted away from the cargo bed access opening. The secondary tailgate in the accessing position at least partially retracted into a portion of the primary tailgate that is vertically beneath the cargo bed access opening when the primary tailgate is in the closed position.
US11208153B2	Front vehicle-body structure of vehicle A connecting reinforcement is provided between a hinge pillar and a wheel house so as to reinforce at least around a rear face portion of the wheel house. The connecting reinforcement extends in the vertical direction along a rear face portion of the wheel house and has a closed-cross section space, in a sectional view perpendicular to the vertical direction, inside thereof. A gusset including a slant face portion which is provided at a front face thereof and configured to extend obliquely rearwardly-and-outwardly is provided in the closed-cross section space. A gap space which forms a part of the closed-cross section space is provided between the slant face portion and the rear face portion of the wheel house provided on a wheel-house side so as to face the slant face portion.
US11208150B2	Automotive frame member and electric vehicle An automotive frame member includes a hat member and a closing plate, in which the hat member includes a top plate, two vertical walls, and two flanges, the two vertical walls are positioned between the top plate and the flanges, respectively, the two vertical walls face each other, the two flanges are respectively joined to the closing plate, each of the two vertical walls includes plural groove parts extending in a direction vertical to a longitudinal direction of the hat member, the groove part includes a bottom surface and two side surfaces, the two side surfaces face each other, the two side surfaces are positioned on both sides of the bottom surface, and a width a of the groove part and a depth b of the groove part in a cross section parallel to the top plate, and a height c of the vertical wall in a direction vertical to the top plate satisfy relations of 0.2≤a/c≤0.3 and 0.2≤b/c≤0.3.
US11208148B2	Node integrated deflector for a vehicle A vehicle frame assembly includes, among other things, a main rail and a node assembly attached to the main rail. The node assembly includes a forward mounting member, a rear mounting member, and a deflector extending between the forward mounting member and rear mounting member. When a load exceeds a threshold load that is applied to a front of a vehicle, the deflector is configured to engage a tire and deflect the tire from entering a forward vehicle area.
US11208147B2	Parking assistance device, parking assistance method, and non-transitory computer readable medium A parking assistance device includes an imager that captures an image of a surrounding of a vehicle, and a display that displays a guidance image for guiding the vehicle from a parking start position to a target parking position and displays a moving area in which the vehicle can move during a parking operation. An area and dimension of the moving area displayed on the display changes based on a change in a steering angle of the vehicle.
US11208145B2	Automated hitching system with steering acquisition and handoff A vehicle hitching assistance system includes a steering system having steered vehicle wheels mounted on an exterior of the vehicle and a steering motor mechanically coupled with the steered vehicle wheels. The system further includes controller that acquires control of the steered vehicle wheels by connection with the steering motor and, after acquiring control of the steered vehicle wheels, receives a command to execute an automated hitching maneuver and controls the steered vehicle wheels using the steering motor.
US11208143B2	Control device for steering mechanism In a control device for a steering mechanism, the steering mechanism includes a motor that includes a plurality of coils. The plurality of coils include a first coil and a second coil. The control device includes a first control system and a second control system configured to compute a command value for torque of the motor to be applied to the steering mechanism. The first control system and the second control system are each configured to control power supply to the plurality of coils of the motor based on the command value. The first control system includes a first microcomputer that has first characteristics, and the second control system includes a second microcomputer that has second characteristics that are different from the first characteristics.
US11208136B2	Multi child stroller A child stroller includes a stroller frame and a first seat. The stroller frame has two sections capable of being folded and unfolded relative to each other. The first seat is disposed on one of the two sections in a detachable manner. The first seat includes a supporting unit and a first seat frame. The first seat frame is adapted to hold the supporting unit. The first seat frame includes a seat hub, an upper seat tube and a lower seat tube. The seat hub is disposed on the stroller frame. The upper seat tube is disposed on the seat hub, and the supporting unit is slidably disposed on the upper seat tube. The lower seat tube is disposed on the seat hub and detachably connected to the supporting unit.
US11208130B2	Method and apparatus to improve unmonitored switch position reporting A switch reporting device including at least one display screen, a high resolution camera, a code reader, at least one memory and one or more processors, the switch reporting device configured to determine a position of an unmonitored switch in a railway by capturing an image of one or more portions associated with the unmonitored switch, generating switch position data based on the image of one or more portions associated with the unmonitored switch, and updating a switch position record for the unmonitored switch with the switch position data. The switch reporting device includes one or more mobile computers or an EOT device for monitoring and reporting switch position data for an unmonitored switch.
US11208129B2	Vehicle control system and method System includes a controller configured to obtain one or more of a route parameter or a vehicle parameter from discrete examinations of one or more of a route or a vehicle system. The route parameter is indicative of a health of the route over which the vehicle system travels. The vehicle parameter is indicative of a health of the vehicle system. The discrete examinations of the one or more of the route or the vehicle system separated from each other by one or more of location or time. The controller is configured to examine the one or more of the route parameter or the vehicle parameter to determine whether the one or more of the route or the vehicle system is damaged. The system also includes examination equipment configured to continually monitor the one or more of the route or the vehicle system responsive to determining that the one or more of the route or the vehicle is damaged.
US11208126B2	DC feeder voltage computing device, DC feeder voltage control system, and DC feeder voltage computation method A DC feeder voltage computing device includes a model information storing unit, a run history information storing unit, and a voltage setting value computing unit. The model information storing unit stores model information. The run history information storing unit stores, on a per train basis, run history information that indicates locations and power situations of a plurality of trains that run in a DC-electrified section on or before a preceding day. The voltage setting value computing unit computes, on the basis of the model information and the run history information, a voltage setting value for controlling a substation voltage to cause an amount of power consumption in the DC-electrified section to satisfy a preset condition.
US11208125B2	Vehicle control system A control system dictates operational settings of a rail vehicle system based a transitory second speed limit that is no faster than a current first speed limit and which is issued for a determined segment of the track for a determined time period. The control system obtains a current time, determines whether the transitory second speed limit has started, is in effect, or has expired based on the current time relative to the determined time period, and, in response to such determination, performs one or more of (a) generate a prompt to indicate that the determined time period has expired, (b) operate the rail vehicle system at the first speed limit, and/or (c) modify the operational settings of the rail vehicle system to exceed the second speed limit in the determined segment but not exceed the first speed limit for the determined segment.
US11208124B2	Follow-up mechanism and brake caliper unit for gauge-changeable bogie The present application relate to a follow-up mechanism and a brake caliper unit for gauge-changeable bogie, the follow-up mechanism includes a follow-up connector, unlocking members that are located on two sides of the follow-up connector and movably connected to the follow-up connector, a transverse displacement recognition device movably connected to the unlocking members, a toothed locking and positioning device mounted on the follow-up connector, and at least two mutually parallel fixation members; the follow-up connector is in sliding fit with the fixation members, and sliders are fixedly connected at ends of the unlocking members; the toothed locking and positioning device is movably connected to the transverse displacement recognition device and fixation members, respectively; the brake caliper unit comprises a mounting bracket, the follow-up mechanism, and a brake actuator mounted on the mounting bracket, the follow-up mechanism is installed in cooperation with the brake actuator, and the fixation members are fixedly mounted on the mounting bracket. The present application can automatically recognize the orbit change of a train, the follow-up mechanism moves with a wheel by means of its stored elastic force and the unlocking members, and can self-locked at the target gauge position, thus realizing the change in position.
US11208122B2	Suspension device for cables and tubings The invention relates to a railway wagon comprising a load carrier (7) and front and rear bogies (8), each of the bogies being provided with railway track wheels and being electrically, hydraulically and/or pneumatically connected to the load carrier by means of one or more electric cables, hydraulic and/or pneumatic tubings (5). The load carrier is releasably connected to the respective bogies, and in a released state laterally displaceable in relation to the respective bogies by means of a displacement device. The load carrier has a front and a rear end and is at each end provided with a support device and a ramp (13), wherein the support device is adapted to support the load carrier on the ground in a position where it is displaced in relation to the bogie, whereas the ramp is along an inner edge pivotally connected to the end of the load carrier. The ramp is provided with a suspension device on the underside of the ramp including a guide arrangement (1) extending transverse in relation to a longitudinal axis of the load carrier, along which guide arrangement a slider (2) is displaceably movable, wherein the slider is provided with a holder (3) for holding of the one or more cables and/or tubings while allowing transverse movement of the cables and/or tubings together with the slider and holder along the guide arrangement.
US11208120B2	Mobile crane systems and methods Systems and methods for a mobile crane are provided. In particular, systems and methods are provided for a mobile crane that is designed to enable easy transportation on a railcar to and from a job site. The mobile crane facilitates quick changing between a transport configuration and a work configuration to enable increased productivity. The mobile crane is configured to be modular and thereby be configured to include various lifting and object manipulating features, as required by a specific application.
US11208118B2	Travel control device, travel control method, and computer-readable storage medium storing program A travel control device for controlling travel of a vehicle, comprises a device that acquires external information of a vehicle; a travel control unit configured to control travel of the vehicle using an acquisition result by the device; a diagnosis start unit configured to start a diagnosis process of the device; and a restriction unit configured to restrict a function of travel control of the vehicle after the diagnosis process of the device is started by the diagnosis start unit according to a state of travel control of the vehicle before the diagnosis process of the device is started.
US11208115B2	Method of assisting autonomous vehicle, and apparatus therefor A method of assisting an autonomous vehicle includes obtaining first surrounding area information of the vehicle when the vehicle is located at a first distance from a monitored area disposed ahead of the vehicle, providing a first control command for controlling the vehicle to operate in a first operating mode, by using the first surrounding area information, obtaining second surrounding area information of the vehicle when the vehicle has driven toward the monitored area and is located at a second distance less than the first distance from the monitored area, and providing a second control command for controlling the vehicle to operate in a second operating mode, by using the second surrounding area information.
US11208114B2	Sensor control apparatus An executing unit is configured to execute at least one of control of operating performance of a plurality of sensors which monitor different regions around a vehicle and predetermined processing for each of a plurality of output values output from the plurality of sensors. A specifying unit is configured to specify a direction of the vehicle with respect to a reference direction set on the basis of a road around the vehicle. A setting unit is configured to set priorities of the plurality of sensors in accordance with the direction of the vehicle specified by the specifying unit. The executing unit changes at least one of ratios of the operating performance of the plurality of sensors and ratios of amounts of processing performed for the plurality of output values on the basis of the priorities.
US11208108B2	Monitoring biological information of a passenger in a vehicle An information providing system for a vehicle includes: first and second mobile terminals worn by a driver and fellow passenger, respectively of the vehicle, and an information providing device, which are communicated with each other. Further, the information providing device includes a control unit that executes information provision control for generating information indicating that the physical condition of the fellow passenger is the predetermined state and transmitting the generated information to the first mobile terminal, in a case where it is determined that the physical condition of the fellow passenger is the predetermined state.
US11208107B2	Systems and methods for selecting among different driving modes for autonomous driving of a vehicle Systems and methods for selecting among different driving modes for autonomous driving of a vehicle may: generate output signals; determine the vehicle proximity information that indicates whether one or more vehicles are within the particular proximity of the vehicle; determine the internal passenger presence information that indicates whether one or more passengers are present in the vehicle; select a first driving mode or a second driving mode based on one or more determinations; and control the vehicle autonomously in accordance with the selection of either the first driving mode or the second driving mode.
US11208106B2	Method for inertia drive control with torque sharing of eco-friendly vehicle A method for inertia drive control with torque sharing of an eco-friendly vehicle includes when an event in which the eco-friendly vehicle being decelerated with the inertia drive control is detected; calculating, by a controller, a distance variable and a speed variable according to the event; calculating, by the controller, a deceleration torque, which is required for an inertia drive of the eco-friendly vehicle, by dividing into a motor torque and a hydraulic braking torque; and performing, by the controller, inertia drive cooperative control in which the deceleration is performed without driver intervention with motor control through the motor torque and hydraulic braking control through hydraulic braking torque.
US11208104B2	Method of providing information to perform inertia driving of vehicle A method of providing inertia drive information to perform inertia driving of a vehicle may include recognizing a target position, where deceleration is required from a current speed of the vehicle, as an inertia drive event on a driving route at which a destination is set by a navigation function, when a plurality of inertia drive events are recognized in the recognizing of the target position as the inertia drive event, determining a predetermined priority with respect to each of the plurality of inertia drive events, determining an inertia drive start position required to reach, at a target speed, a target position of an inertia drive event having a high priority, which is determined by the determining of the predetermined priority, among the plurality of inertia drive events, and providing information on an inertia drive start position through a method which is recognizable by a driver.
US11208103B2	Vehicle control device The present invention relates to a vehicle control device for automatically controlling at least a part of the drive control of the host vehicle. If an external condition detecting unit detects a first other vehicle subject to following control and a second other vehicle which exhibits the traveling movements of cutting in between the first other vehicle and the host vehicle, a deceleration limiter sets limits that differ depending on whether or not the relative speed of the host vehicle vis-a-vis the second other vehicle exceeds a speed threshold having a positive value.
US11208101B2	Device and method for measuring transverse distribution of wheel path A device of measurement of transverse distribution of a wheel path. The device includes a measurement device, a first database, an analysis device, and a second database. The measurement device is configured to measure a shape and size of one side of a horizontal section of each of a plurality of vehicles, and to measure a distance between the one side of the horizontal section of each of the plurality of vehicles and a road shoulder. The first database is configured to store data of the shape and size of one side of the horizontal section of each of the plurality of vehicles, and of the distance between the one side of the horizontal section of each of the plurality of vehicles and the road shoulder, and raw data of a shape and size of one side of a horizontal section of a plurality of wheels.
US11208098B2	Camera system for intelligent driver assistance system, and driver assistance system and method An advanced driving assistance system (ADAS) provides collision avoidance control for a host vehicle. The system can include one or more sensors mounted to the host vehicle and configured to sense a driving lane in which the host vehicle is traveling and to sense an external vehicle partially engaged in the driving lane. A controller controls steering, braking, or acceleration of the host vehicle on the basis of sensing information received from the sensor. The controller determines the external vehicle partially engaged in the driving lane as a target vehicle having at least a part thereof overlapping with a lane mark of the driving lane, and performs longitudinal braking or acceleration control or lateral steering control on the host vehicle based on lateral and longitudinal positional relationships between the host vehicle and the target vehicle.
US11208095B2	Control device and control method for vehicle A control device for a vehicle having a drive shaft, an engagement element, an engine connected to the drive shaft via the engagement element, and an electric motor connected to the drive shaft not via the engagement element includes a control portion adapted to stop the engine after a maintaining period in which the engine is maintained at predetermined rotation speed during travel of the vehicle. The a control portion gradually decreases an engagement volume of the engagement element while gradually increasing a power generation load of the electric motor during the maintaining period to disengage the engagement element, and stops the engine after disengagement of the engagement element.
US11208089B2	Drive-force control apparatus for vehicle A drive-force control apparatus for a vehicle including a first drive apparatus for driving a first pair of wheels and a second drive apparatus for driving a second pair of wheels. Each of the first pair of wheels is one of front and rear wheels of the vehicle, and each of the second pair of wheels is the other of the front and rear wheels. During running of the vehicle on a wave-like road, the control apparatus reduces a drive-force share ratio of one of the first and second drive apparatuses, and to increases a drive-force share ratio of the other of the first and second drive apparatuses, wherein the one of the first and second drive apparatuses includes a weakest part that is to be damaged the most easily among parts composing the first and second drive apparatuses, by resonance caused by the running on the wave-like road.
US11208086B2	Hydraulic pressure controller, straddle-type vehicle brake system, and straddle-type vehicle A hydraulic pressure controller, cost of which can be cut, a straddle-type vehicle brake system, and a straddle-type vehicle are obtained.A hydraulic pressure controller (110) is used for the straddle-type vehicle brake system which includes a single system of a hydraulic circuit capable of controlling a hydraulic pressure and in which brake fluid in a wheel cylinder is released to a master cylinder without increasing the hydraulic pressure. A first coil (112B), a second coil (113B), and a hydraulic pressure detector (116) are erected on the same surface of a base body (111). An axis of the hydraulic pressure detector (116) is offset from a reference plane including an axis of the first coil (112B) and an axis of the second coil (113B), and is located between a first plane that is orthogonal to the reference plane and includes the axis of the first coil (112B) and a second plane that is orthogonal to the reference plane and includes the axis of the second coil (113B).
US11208084B2	Brake assistance apparatus and brake assistance control method for vehicle A brake assistance apparatus for a vehicle is provided. The brake assistance apparatus includes a detecting unit and a brake assistance control unit. The detecting unit detects a state surrounding an own vehicle. The brake assistance control unit performs brake assistance to brake the own vehicle at a first brake timing, based on the detected state surrounding the own vehicle. In response to the own vehicle being determined to be advancing at an intersection based on the detected state surrounding the own vehicle, the brake assistance control unit performs the brake assistance at a second brake timing that is later than the first brake timing.
US11208081B2	Hydrogen station The present application discloses a hydrogen station for supplying hydrogen to a tank of a tank-equipped device. The hydrogen station includes: an integrated controller for integrally controlling devices provided in the hydrogen station; a sensing portion for sensing leaked hydrogen which has leaked inside the integrated controller; a ventilation device performing a high ventilation measure of performing ventilation for air inside the integrated controller or an explosion prevention device performing an internal pressure-based explosion protection measure of creating a pressure-increased state inside the integrated controller; and a compressor unit including a compressor, which is used as one of the devices, and a housing, in which the compressor is stored. The integrated controller is mounted on the housing, and is electrically connected to the compressor via a through-hole formed in the housing to control the compressor.
US11208072B2	Ejector and gas generator An ejector for ejecting a combustion product including, an igniter including an ignition charge and an ignition portion, a pyrotechnic agent, and a cup made of metal, the cup including a bottom surface and a peripheral wall, the peripheral wall being contiguous with a peripheral edge of the bottom surface and disposed to surround the ignition portion, the cup further including an accommodating space accommodating therein the pyrotechnic agent, the bottom surface of the cup including a through hole being defined by a plurality of through-hole peripheral edges, and the adjacent through-hole peripheral edges being connected together at a predetermined connection point, and the through hole including a narrow part, in which a width of the through hole defined by each of parts of the two through-hole peripheral edges of the plurality of through-hole peripheral edges decreases gradually with an increasing distance from a center of the bottom surface toward the peripheral edge of the bottom surface, and the narrow part being located closer to the peripheral edge of the bottom surface than a non-narrow part, which is defined by each of other parts of the two through-hole peripheral edges, is located.
US11208071B2	Airbag Provided is an airbag which further reduces the degree of injury to a vehicle occupant while also exhibiting sufficient occupant protection performance using less output from the inflator, by both preventing airbag internal pressure from rising excessively when making contact with the occupant and increasing the speed of deployment in an occupant-protection area. This hollow-weave airbag has an opening in a main chamber that inflates for the purpose of occupant protection, a structure wherein a first yarn extending separatingly from a first fabric layer of the opening to a non-inflating portion is caught on a float yarn extending on the inside of a second fabric layer and subsequently caught on a float yarn extending on the inside of the first fabric layer, this structure being repeated at least once and forming a pair with another structure wherein a second yarn extending separatingly from the second fabric layer of the opening to the non-inflating portion is caught on the float yarn extending on the inside of the first fabric layer and subsequently caught on the float yarn extending on the inside of the second fabric layer, this structure being repeated at least once.
US11208065B2	Vehicle bumper support assemblies A vehicle is provided including a bumper attachment member, a radiator support beam, and a bumper support assembly coupled to the bumper attachment member and the radiator support beam. The bumper support assembly includes a center stay fixed to the radiator support beam and a center stay support having a receiver, an arm, and an anti-rotation pin. The arm extends in a vehicle-longitudinal direction from the receiver. The receiver is configured to receive and engage the bumper attachment member. The anti-rotation pin extends in the vehicle-lateral direction proximate an end of the arm opposite the receiver and engages the center stay to inhibit movement of the bumper attachment member with respect to the radiator support beam.
US11208064B2	Crash box for a bumper The invention relates to a crash box (3) comprising two generally U-shaped members (11, 12) having legs (11a, 12a) and provided at respective leg with at least two adjacent trigger means (13) and an intermediate portion (14) formed between said trigger means (13). The U-shaped members (11, 12) is welded together at areas along a trim edge (15) except for the trim edge (15) formed between respective legs of respective trigger means (13) so as to form a crash box (3) having aligned trigger means (13) and intermediate portion (14). The trigger means (13) are arranged normal to crash box (3), and the intermediate portion (14) of respective leg (11a, 12a) is welded together at the trim edge (15) thereof by a weld bead (20) having a length (L) which is longer that the shortest length (1) between two adjacent trigger means (13). The invention also relates to a method for producing such a crash box.
US11208060B2	Configurable management system for a vehicle and method of use A configurable management system for a vehicle includes a receiving unit adapted to receive a message associated with a vehicle resource from a communication network of the vehicle. A control unit is adapted to determine a vehicle resource associated with the received message. An integration unit includes an external network connected to the control unit and the integration unit further includes at least one node, wherein the at least one node is configured to send an external message on the external network to the control unit. The control unit converts the external message to a suitable message that is sent to the vehicule resource.
US11208050B1	Expandable cargo carrier A system for an expandable cargo carrier including a carrier assembly, a communication assembly and a vehicle assembly is disclosed. The carrier assembly includes a carrier that is secured to a vehicle of the vehicle assembly with an attaching member. The carrier includes a floor defined by telescopic members. The telescopic members expand or retract to achieve an expanded or retracted configuration, respectively, for the carrier. The carrier is expanded or retracted through manual or automatic means. The communication assembly includes a motor that is engaged to expand or retract the telescopic members automatically. Additionally, communication assembly permits carrier to be sized remotely. Alternatively, telescopic members are expanded or retracted through manual manipulation of the telescopic members. Carrier is sized as necessary by a user to accommodate a cargo load to be transported within carrier.
US11208045B2	Power retractable bumper step A power box step on a vehicle having a safety arrangement that provides noticeable controlled failure of the power box step if damaged. The controlled failure is accomplished by using vertical and horizontal shear pins that are designed to break when the horizontal or vertical load applied to the step is too great. The failure of the step is controlled by vertical and horizontal movement limit pins that prevent the step from moving too far in the vertical or horizontal direction when failure occurs.
US11208042B2	Auto-switch display intelligent rearview mirror system A motor vehicle includes a rearview mirror display system with a visible surface and having a mirror mode and a display mode. The visible surface functions as a mirror in the mirror mode. The visible surface displays an electronically produced image in the display mode. An electronic processor is communicatively coupled to the rearview mirror display system. The electronic processor detects that the display mode is not operating properly, and, in response to the detecting, automatically switches the rearview mirror display system from the display mode to the mirror mode.
US11208040B2	Display system and work vehicle Provided is a display system, which makes it easy for an operator to accurately grasp a traveling situation of a work vehicle. A front camera captures an excavating blade and topography in front of a crawler dozer. A rear camera captures a fuel tank and a ripper apparatus, and a topography behind the crawler dozer. A display image displayed on a monitor is generated by arranging a front image captured by the front camera and a rear image captured by the rear camera so that the excavating blade in the front image may face the fuel tank in the rear image.
US11208039B2	Vehicular surveillance system The invention is a vehicular surveillance system that captures images of road and vehicles in front of a vehicle as well as position and gaze of a driver. The images are captured and stored so as to enable someone to access image data captured prior to and at the time of an accident.
US11208035B2	Lighting apparatus for a motor vehicle A lighting apparatus for a motor vehicle has a lighting module. The lighting module includes a laser light source for generating laser light. The laser light source has one or more laser diodes. The lighting module also includes an optical device on which the laser light is incident and which is designed to generate a defined symbol in the surroundings of the motor vehicle. The optical apparatus includes one or more holographically optical elements which are substantially non-absorbent to the laser light and which are designed to produce an interference of the laser light by phase modulation thereof in order to generate the defined symbol.
US11208034B2	Vehicle lamp assembly A lamp assembly is provided herein. The lamp assembly includes a panel operably coupled with one or more projectors. A light source is disposed within each of the one or more projectors. An optical member is disposed between each of the light sources and the panel. An image interference is disposed between the optical member and an exterior surface of the panel.
US11208032B2	Vehicle capable of projecting light onto road and control method therefor A vehicle projects various types of light beams onto a road using a light-emitting module. The light-emitting module includes: a reflection unit, and a light source unit to emit light to the reflection unit. The reflection unit includes: a first pole magnet and a second pole magnet facing each other while being spaced apart from each other; a plate disposed between the first pole magnet and the second pole magnet, and a wire disposed in a multiple number of turns in one direction along an edge of the plate; and a reflection surface disposed on the upper surface of the plate.
US11208018B1	Headrest assembly for a pivoting headrest A headrest assembly includes a pivot pin rotatably coupled to a support structure. A pivot member extends outward from a headrest body and is coupled to the pivot pin. A lock assembly is disposed about the pivot pin and is operable between a disengaged condition and an engaged condition. In the engaged condition, rotation of the pivot pin relative to the support structure is generally prevented. A pulley wheel is operable to rotate about the pivot pin from a first position to a second position to prompt the lock assembly to enter the disengaged condition.
US11208017B2	Motor vehicle seat, motor vehicle equipped therewith and method for adjusting a cover tension of the motor vehicle seat To improve comfort, a motor vehicle seat has at least one cushion body, at least one cover concealing the cushion body at least in part, and at least one tensioner, which is operatively connected to the cover by a first end and is designed to adjust the cover tension. The tensioner is fixed by a second end to a clamping device. The clamping device is designed to modify and fix the distance of the tensioner from the first end thereof to the second end thereof and the clamping device is designed to be operated after completion of the motor vehicle seat.
US11208016B2	Ventilation device for vehicle seat A device for ventilating the occupant of a vehicle seat, comprising an air inlet receiving air from a ventilation member, and comprising a first duct integrated at least in part into the backrest of the seat, a second duct integrated into a headrest mounted on the seat and supplying at least one air outlet integrated into the headrest and expelling air coming from the ventilation member, the second duct and first duct being connected by a leaktight sliding connection.
US11208014B2	Support base for a child safety seat A support base for a child safety seat includes a shell, a belt clamp, a latching mechanism and a belt retaining structure. The shell is adapted to receive a child seat thereon, and has a panel at an end thereof. The belt clamp is pivotally connected with the shell and is disposed adjacent to the panel, the panel rising above the belt clamp, the belt clamp being operable to clamp a lap belt portion of a vehicle safety belt adjacent to a surface of the shell. The latching mechanism is operable to lock the belt clamp in a clamping state. The belt retaining structure is provided on the panel, and is configured to hold a shoulder belt portion of a vehicle safety belt adjacent to the panel.
US11208011B2	Apparatus for controlling seat of vehicle, system having the same, and method thereof An apparatus for controlling a seat of a vehicle, a system having the same, and a method thereof are provided. The apparatus for controlling a seat of a vehicle includes a digital key positioning device to measure a position of a digital key inside the vehicle and the number of the digital key, an occupant sensor to sense an occupant condition inside the vehicle, a controller to determine a target for seat-controlling based on the position of the digital key, the number of the digital key, and the occupant condition, and a seat controller to control a position of a seat using seat control information, which is received from the digital key, for each user.
US11208007B2	Direct current power supply circuit mounted in working vehicle There is provided a direct current power supply circuit mounted in a working vehicle with increased safety as compared with related art by a configuration where a main power source is used after a battery management system (BMS) determines that the main power source can be used. A direct current power supply circuit includes a first power source, a switch, a second power source and a first relay, in which the first power source is connected to a battery management system through the first relay so as to supply direct current power, the battery management system is activated by supply of direct current power from the second power source when the switch is turned on, and the first relay is on-controlled when determined that the first power source can be used.
US11207999B2	Charger and charging method for charging the battery of an electric motorcycle by using charging stations for cars A charger includes a first connection port, a second connection port, a DC-DC converter, a first microcontroller, and a second microcontroller. The DC-DC converter is configured to convert a first DC voltage into a second DC current/voltage according to a regulation signal, and output the second DC current/voltage through the second connection port. The second DC voltage is lower than the first DC voltage. The first microcontroller is configured to communicate with a DC charging station by handshake via the first connection port. When the handshake between the first microcontroller and the DC charging station succeeds, the first microcontroller generates a regulation indication according to a result of the handshake between the first microcontroller and a battery, the second microcontroller generates the regulation signal according to the regulation indication, and the first DC voltage is supplied by the DC charging station.
US11207997B2	Charging robot and device for controlling same Disclosed is a device for controlling one or more charging robots in a charging station including a plurality of charging sectors. The device includes a communication unit for communicating with the charging robot, an inputter for inputting an image signal, and a controller, wherein the controller may recognize the electric vehicle entering the charging sector based on information inputted through the inputter, select a charging robot that is located at a close distance from the charging sector and is directly movable to the charging sector, and cause the selected charging robot to move to the charging sector. Accordingly, a charging robot and a control device having artificial intelligence and performing 5G communication can be provided.
US11207995B2	System and method for charging machines A method includes causing, with a controller, operation of a first compaction machine at a worksite based at least in part on a worksite plan. The method also includes determining, with the controller, a return path extending from a current location of the first machine to a charging zone located at the worksite, and determining, with the controller, a return power required for the first machine to traverse the return path. The method further includes causing, with the controller, the first machine to traverse the return path, from the current location to the charging zone, based on at least one of the return power and an amount of available power stored in an energy storage device of the first machine.
US11207993B2	Storage-battery charging device for a motor vehicle, method for operating an on-board storage-battery charging device, high-voltage vehicle electrical system and use of a storage-battery charging device A storage-battery charging device for a motor vehicle is configured to be arranged in the motor vehicle. The storage-battery charging device includes a first stage with a power factor correction filter, and a second stage with an inverter. The first stage is electrically connected to the second stage through an intermediate node, the intermediate node being directly electrically connected to a feed-in connection point for direct voltage. The feed-in connection point is designed for direct electrical coupling to a high-voltage vehicle electrical system of the motor vehicle.
US11207986B2	Scaled home energy storage systems and associated uses This disclosure details exemplary home energy storage systems capable of storing electricity locally for later consumption, such as for charging an electrified vehicle, supporting various home energy needs, and supporting alternative energy storage/power source functionality. An exemplary home energy storage system may include a stationary unit, one or more modular units removably connectable to the stationary unit, and a rack mounting and handcart transportation system configured to mount, detach, and transport the modular unit relative to the stationary unit. Once undocked from the stationary unit, the modular unit(s) may be utilized as a portable power source for powering one or more electrical loads. This disclosure further describes various interconnected functionalities (e.g., electrical and wireless communication of state of uses) between the stationary unit and the modular unit of home energy storage systems and between the modular unit and various satellite equipment associated with the modular unit.
US11207985B2	Power supply device A power supply device includes a storage battery; a capacitor unit having first and second capacitor; a three phase power converter, connected in parallel with the storage battery, each phase having first to fourth switching elements in series; three connection terminals electrically connectable to a three-phase AC charger; and a control unit, in a case where the three connection terminals and the three-phase AC charger are electrically connected between the first switching elements and the second switching elements for the respective three phases in the three-level inverter, before the storage battery is charged by means of the three-phase AC charger, charging the first capacitor with use of the storage battery and setting voltage of the second capacitor to 0 V.
US11207976B2	Axle assembly having a multi-speed countershaft transmission An axle assembly having a countershaft transmission. The countershaft transmission may operatively connect an electric motor to a drive pinion. The countershaft transmission may have a first countershaft subassembly that is rotatable about a first countershaft axis and a second countershaft subassembly that is rotatable about a second countershaft axis.
US11207974B2	Multiple gas tank assembly with individual pressure monitoring This disclosure describes an assembly for gas (e.g., compressed natural gas) storage. The assembly includes multiple gas storage tanks, with each tank coupled to a separate sub-assembly that includes a pressure gauge, shutoff valve, and pressure relief device (PRD), providing for independent pressure monitoring, shutoff, and pressure relief for each of the tanks.
US11207970B2	Integrated drive unit having an electric drive and a mechanical brake A drive and deceleration unit has a mechanical brake and an electric drive. The mechanical brake and the electric drive are provided as a unit for acting on a single wheel connection. A method provides for the open-loop and/or closed-loop control of such a drive and deceleration unit.
US11207965B2	Motor vehicle with transmission and transmission fluid pump A motor vehicle includes a transmission and a transmission fluid pump for transport of transmission oil to and within the transmission. The transmission fluid pump has a moving element which is coupled to a summation shaft of a planetary gear train. The planetary gear train has a ring gear which is operated by a first drive, and a sun gear which is operated by a second drive. A freewheel mechanism is arranged between the sun gear or a shaft connected to the sun gear and a further element so that the second drive can be switched off, when the first drive operates at high speeds while yet maintaining proper operation of the transmission fluid pump.
US11207960B2	Self-deploying and self-retracting automobile cover A self-deploying and self-retracting automobile cover system. The system including an actuator mechanism, a housing unit and a cover. The actuator mechanism controls the operation of the cover, wherein the actuator mechanism triggers the automatic deployment of the cover such that the cover expands outward from the housing unit and triggers the automatic retraction of the cover such that the cover collapses into the housing unit. Upon deployment, the deployed cover is configurable to operate as a touchless cover such that each shield member of the pair of coverlets is void of any physical contact with the automobile or is configurable to operate as a touch cover such that each shield member of the pair of coverlets is in physical contact with the automobile.
US11207958B2	Vehicle door arrangement configured to prevent overlap An exemplary motor vehicle includes a first door on a first side of the motor vehicle including a first pad adjacent a rear edge of the first door, and a second door on the first side of the motor vehicle including a second pad adjacent a front edge of the second door. Further, the first pad and second pad are arranged such that, in a first condition, the first pad and second pad are spaced-apart from one another and, in a second condition, the first pad and second pad contact one another to prevent overlap of the first door and second door.
US11207955B2	Front door A front door includes: a door body; a door sash configuring a window frame; a window disposed in the window frame; and a pillar having an upper end connected to a front end of an upper sash of the door sash, the upper sash supporting an upper edge of the window, the pillar having a lower portion fixed to the door body. The pillar includes a frame portion extending downward from a connection position between the upper sash and the pillar. A window supporting portion is coupled to the frame portion above the door body so as to extend frontward from the frame portion. The window supporting portion is located more frontward than the frame portion as the window supporting portion is located more downward. A front end of the window is supported by the window supporting portion at a position more frontward than the frame portion.
US11207950B2	Air vent So as to guide an air current flowing out of an air vent for a motor vehicle, an air deflection element, which can be moved transversely in an air channel of the air vent, is disposed upstream of an air guide body in a flow direction, which includes air passages, for which the air deflection element includes congruent windows.
US11207939B2	Vehicle thermal management system and heat exchangers A vehicle thermal management system includes selective use of a liquid cooled gas cooler (LCGC) and conductive heat exchangers between heating, cooling, battery, and powertrain thermal management loops to increase temperature control and efficiency of the system.
US11207935B2	Electronic control device and control circuit for an air suspension system of a commercial vehicle An air suspension system of a commercial vehicle comprises an electronic control device with a level control valve device. A valve element is coupled to a drive element mechanically coupled to a vehicle wheel or axle. In a first relative position of the valve element and a counter valve element, a port for an air suspension bellow is blocked. In a second relative position, the port for the air suspension bellow is connected to a port for an aeration device. In a third relative position, the port for the air suspension bellow is connected to a port for a deaeration device. Control logic generates a control signal for an actuator which, when a level change is set by an operator, correspondingly changes the relative position of the valve element and the counter valve element or the relative position of the counter valve element and a valve housing.
US11207930B2	Tire pressure control system A tire pressure control system can include a pneumatic line with a first end in fluid communication with an interior of a tire and a pressure sensing device configured to acquire pressure data within the tire measured from the single pneumatic line. A motion sensing device can be configured to acquire motion data of the tire pressure control system. A microcontroller can receive the pressure data from the pressure sensing device and the motion data from the motion sensing device. A pneumatic solenoid in fluid communication with a second end of the single pneumatic line can be in an initial, closed position. The microcontroller can open the pneumatic solenoid and release fluid from the interior of the tire when the pressure data and motion data meet preset conditions.
US11207928B2	Pneumatic tire A pneumatic tire includes: paired bead portions respectively including annular bead cores and bead fillers disposed on an outer side in a tire radial direction of the bead cores; sidewall portions respectively extending outward in the tire radial direction from the bead portions; a tread portion connected to cuter ends in the tire radial direction of the sidewall portions to form a tread; and a carcass layer suspended between the bead portions. The carcass layer has a first ply that continuously extends between the bead portions and that has opposite end portions respectively and a second ply that continuously extends on the outer side in the tire radial direction of the first ply, wherein the first ply has higher tensile strength than that of the second ply, and the end portion is positioned on the outer side in the tire radial direction of the end.
US11207927B2	Pneumatic tire A pneumatic tire includes a pair of sidewall portions. At least one of the pair of sidewall portions is provided with circumferentially spaced protrusions protruding axially outwardly. Each of the protrusions includes a first end in a tire circumferential direction and a recess extending in the tire circumferential direction from the first end and having a terminal end terminating within the protrusion.
US11207925B2	Tire This disclosure aims to provide a tire having excellent braking performance on dry road surface and on wet road surface, and having excellent steering stability. This disclosure is a tire comprising a tread 10, wherein: the tread 10 has a plurality of circumferential grooves extending continuously in a tire circumferential direction C, the circumferential grooves including circumferential main grooves 21a, 21b, 22 with a cross-sectional area in a tire width direction W of 10 mm2 or more, and a groove width Lb at a 95% groove depth position with a groove depth of a groove bottom as 100% of at least the circumferential groove 21a located on an outermost side when mounted to a vehicle among the circumferential main grooves 21a, 21b, 22 being 25% to 60% with respect to a groove width Lt on a tread surface.
US11207920B2	Pneumatic tire The pneumatic tire according to the disclosure includes a resin-coated belt comprising a wire coated with a coating resin. A base ring is formed at a tire radial inside of the resin-coated belt, while being in contact with a tire widthwise outer end of the resin-coated belt. A concavo-convex portion is formed on at least one of surfaces of the base ring.
US11207917B1	Wheel assembly A wheel assembly includes: a wheel set unit including a wheel bracket and a wheel; and a brake unit including a brake element disposed between the wheel bracket and the wheel, a threaded member sleeved movably on the brake element, and a screw extending threadably through the threaded member, extending through the brake element so as to prevent movement of the threaded member on the brake element, and pushable downwardly such that the brake unit moves downwardly to press resiliently against the wheel, so as to arrest rotation of the wheel. Only a single tool is needed to be accessed to a lower end of the screw so as to adjust a distance between the brake unit and the wheel.
US11207913B2	Erasing member and erasing tool using the same Provided are an erasing member which is excellent in erasability for handwritings written by means of a pencil, a mechanical pencil and the like and which does not produce eraser dusts, and an erasing tool in which a part to be erased can be visually recognized in erasing.The erasing member comprises a blend composition containing a liquid-absorbing porous material, and a basic magnesium carbonate porous material and the like can be used as the liquid-absorbing porous material. And in an erasing tool in which an erasing part is formed at one end and in which a transparent or translucent visible part making it possible to visually recognize a writing surface is provided in the vicinity of the erasing part, the erasing member described above is mounted to the erasing part, whereby the erasing tool which does not produce eraser dusts is obtained.
US11207912B2	Writing utensil safety sheath A writing utensil safety sheath comprising a body having a first open end and an internal channel. The internal channel is sized to retain at least a portion of a writing utensil in either a first extended position or a retracted position. The writing utensil safety sheath also has a grip affixed to and extending beyond the first open end of the body. The grip contacts a writing end of the writing utensil when the writing utensil is in the first extended position thus retaining the writing utensil in the first extended position while writing. When a force applied to the writing end exceeds a predetermined amount, the writing utensil retracts back into the body by sliding through the grip into the first open end of the body.
US11207911B2	Folder savers The present technology relates generally to devices and methods for preserving the integrity of folders that are placed into ringed binders or notebooks, preferably folders that are made of paper or other like material, and which are used for example for the transport and storage of papers by students or other types of users.
US11207908B2	Fabric print medium A fabric print medium comprising a fabric base substrate; a primary coating composition with a polymeric binder and filler particles applied to, at least, one side of the fabric base substrate; an image-receiving coating composition with a first and a second crosslinked polymeric network applied over the primary coating composition; and a barrier layer comprising a water-repellent agent and a physical gelling compound. Also disclosed are the method for making such fabric print medium and the method for producing printed images using said material.
US11207906B2	Cleaning device and image forming apparatus A cleaning device includes a cleaning unit which removes foreign matter adhered on a conveyance face of a conveyance member conveying a sheet, by using a belt shaped web; and a unit moving mechanism which displaces the cleaning unit to a cleaning position where the cleaning unit comes into contact with the conveyance face and to a separation position separated away from the cleaning position. The cleaning unit includes a delivery roller delivering the web, a pressure roller bringing the web pressure-contact with the conveyance face and a winding roller winding the web passed the conveyance face. The cleaning unit is tilted such that a cleaning face of the web between the pressure roller and the winding roller faces upward as the cleaning unit is displaced from the cleaning position to the separation position.
US11207903B2	Medium transport device and recording apparatus A medium transport device includes a first roller that applies a transporting force to a medium, a second roller that applies a transporting force to the medium transported from the first roller, a third roller that applies a transporting force to the medium transported from the second roller, a first rotor that transmits rotational torque to the third roller, a first shaft that is provided away from the first rotor at a first interval, and a second shaft that is provided away from the first rotor at the first interval and at a position different from a position of the first shaft. A shaft center of the first shaft and a shaft center of the second shaft are positioned on a circular arc, the center of which is a rotation center of the second roller.
US11207902B2	Printing apparatus having multiple heaters with overlapping heat zones There is provided a printing apparatus including: a transport section that transports a medium in a first direction; a printing section that makes a liquid adhere to the medium transported by the transport section; a heating section provided downstream of the printing section in the first direction, in which the heating section includes a first heater that extends to a first range in a second direction intersecting the first direction and a second range positioned on one side in the second direction from the first range and heats the medium, and a second heater that extends to the first range and a third range positioned on the other side in the second direction from the first range, and heats the medium, and heats the medium by the first heater and the second heater when the printing section made the liquid adhere to the first range on the medium.
US11207900B2	Recording device and recording method for controlling a medium heater A recording device includes a medium placement unit on which a medium is fixedly placed, a recording head configured to discharge liquid toward the medium, a gantry including a discharging unit, the gantry being configured to move relative to the medium placement unit along a first axial direction, a heater provided at the medium placement unit, the heater being configured to heat the medium placed on the medium placement unit, and a control unit configured to control the heater. The control unit controls heating of the medium by the heater in accordance with a condition.
US11207897B2	Printing jig and method for manufacturing printed objects Provided are a printing jig for an inkjet-type printer and a method for manufacturing printed objects therewith, which jig can be easily produced in accordance with the shape and size of an object to be printed and allows the object to be accurately positioned relative to the printer. The printing jig supports an object to be printed, and is placed in an inkjet-type printer when the object is being printed. The printing jig includes a mounting surface on which the object is to be placed, and a positioning part for positioning the object. The positioning part includes a protrusion preformed on the mounting surface so as to be brought into contact with at least part of the object placed on the mounting surface. The protrusion is made of deposited and cured ink used by the inkjet-type printer.
US11207894B2	Bubblers to provide sequential fluid flow An example device includes a first chamber to contain a first fluid and a second chamber to contain a second fluid. The first chamber includes a first fluid outlet, and a first bubbler to ingest bubbles into the first chamber when pressure in the first chamber overcomes a first bubble pressure of the first bubbler. The second chamber includes a second fluid outlet, and a second bubbler to ingest bubbles into the second chamber when pressure in the first chamber overcomes a second bubble pressure of the second bubbler. An outlet node is fluidly connected to the first fluid outlet and the second fluid outlet. The outlet node draws the first fluid from the first chamber when the first bubbler ingests bubbles, and sequentially draws the second fluid from the second chamber when the second bubbler ingests bubbles.
US11207890B2	Head array, head module, discharge unit, and liquid discharge apparatus A head array includes heads arranged in a longitudinal direction at different positions shifted in a direction orthogonal to the longitudinal direction. Each head includes: pressure chambers communicating with nozzles; common supply channel tributaries communicating with the chambers; a common supply channel mainstream communicating with the common supply channel tributaries; common collection channel tributaries communicating with the chambers; a common collection channel mainstream communicating with the common collection channel tributaries; a supply port at one end of the common supply channel mainstream; and a collection port at one end of the common collection channel mainstream. The supply and collection ports are on a same side of each head in the longitudinal direction. A direction of flow of the liquid in each common supply channel tributary is opposite between the heads. A direction of flow of the liquid in each common collection channel tributary is opposite between the heads.
US11207886B2	Print head and liquid ejecting apparatus A print head includes ejecting portions ejecting liquid by being supplied with a high voltage signal, a switch group switching between whether or not to supply the high voltage signal to the first ejecting portion group in accordance with a low voltage logic signal, a memory, a high voltage signal input terminal, and a low voltage logic signal input terminal, the print head having a first mode in which the print head executes reading processing of reading information stored in the memory and does not execute ejection control processing of controlling whether or not to supply the high voltage signal to the first ejecting portion group by switching the switch group in accordance with an input signal input from the low voltage logic signal input terminal and a second mode in which the print head does not execute the reading processing and executes the ejection control processing.
US11207881B2	Sheet processing machine with shaping device and upper suction transport means A sheet processing machine has at least one shaping device and at least one sheet delivery unit, arranged downstream of the at least one shaping device along a transport path provided for a transport of sheets. The at least one shaping device has at least one shaping point which is formed by at least one forme cylinder, on one hand, and at least one impression cylinder, on the other hand. At least one separation device, for removing scrap pieces from sheets, is arranged downstream of the at least one shaping point along the transport path provided for the transport of sheets. The at least one separation device has at least one separation transport device. At least one transport device, configured as a selective transport device, is arranged following the at least one separation transport device along the transport path provided for the transport of sheets. The transport device is configured as at least one upper suction transport device for a hanging transport of sheets.
US11207880B2	Device, method and printing press for multiple printing of printing substrate sheets The invention relates to a device for printing sheets of printing substrate (02), having a first printing nip (12) which is formed between a first cylinder (19; 19) that acts as a transport cylinder (19; 19) and a second cylinder (18), and in which the printing substrate sheets (02) can be printed on one or on both sides with one or more collected print image segments, and having a second printing nip (11) lying downstream in the printing substrate path, which printing nip is disposed at a level lying below the first printing nip (12) and is formed between a third cylinder (17) that acts as a transport cylinder (17) and a fourth cylinder (16), and in which the printing substrate sheets (02) can be printed on one or on both sides with one or more collected print image segments, wherein the printing substrate sheets (02) can be conveyed via at least one rotating transport means (33; 38; 39) along a transport path from the cylinder (19; 19) that acts as a transport cylinder (19; 19) of the first printing nip (12) to the cylinder (17) that acts as a transport cylinder (17) of the second printing nip (11), wherein on the transport path, downstream of the cylinder (19; 19) that acts as a transport cylinder (19; 19) of the first printing nip (12) and upstream of the cylinder (17) that acts as a transport cylinder (17) of the second printing nip (11), at least one first electrode (37; 41) directed toward the outer circumference of the at least one rotating transport means (33) is arranged in an angular segment lying in the transport path for the printing substrate sheets (02) in such a way that when an electric voltage is applied, a printing substrate sheet (02) being guided past the electrode (37; 41) can be electrostatically charged.
US11207877B2	Structural rework of cellular core panels Methods for reworking structures and reworked cellular core panels, reworked structures comprising the reworked cellular core panels, and guides and cutting apparatuses for reworking cellular acoustic panels and reworking cellular acoustic and non-acoustic panels are disclosed.
US11207874B2	Methods of making fibrous structures with shaped polymer particles A method of forming a fibrous structure including: providing a first textured substrate that has a first side with first discrete regions and a first continuous region extending between the first discrete regions, and a second side comprising a plurality of first discrete portions corresponding to the first discrete regions and a first continuous portion corresponding to the first continuous region; passing the first textured substrate across a nozzle of a slot coat header, wherein a heated polymer is dispensed from the nozzle; depositing the heated polymer onto one of the first or the second side of the first textured substrate to form a plurality of first polymer particles, wherein the heated polymer is substantially deposited on an area of the first textured substrate that contacts the nozzle such that at least a section of each of the first polymer particles defines a raised edge; and joining the first textured substrate to a second substrate to form the fibrous structure.
US11207867B1	Bio-inspired composite laminate design with high out-of-plane strength and ductility Bio-inspired carbon fiber reinforced polymer (CFRP) composite laminates are provided. The CFRP laminates display high out-of-plane strength and ductility due to the incorporation of defects (e.g. areas of delamination) which are purposefully introduced into the laminate layers.
US11207856B2	Tire vulcanizer and tire manufacturing method A tire vulcanizer is disclosed that has superior durability and in which mold parting surfaces defined by a sector and side plates are less likely to be worn even after repeated use. The tire vulcanizer includes: the sector that shapes a tread of a tire; paired upper and lower side plates that shape sidewalls of the tire; a segment that is fixed to the sector and causes the sector to move in a tire radial direction; paired upper and lower attachment plates that are respectively fixed to the paired upper and lower side plates; and the mold parting surfaces defined by the sector and the side plates. Mold inner ends of the mold parting surfaces are arranged on the tread, and the mold parting surfaces extend outward in the tire radial direction from the mold inner ends.
US11207851B2	Puncture repair liquid holding container Provided is a puncture repair liquid holding container. An outflow channel in a cap mounted to an opening portion of a container body for discharging the puncture repair liquid inside the container interior to a container exterior includes a straight portion including an open end opening toward inside the container body and a closed end terminating inside the cap, and a branching portion including a communicating end communicating with an intermediate area of the straight portion and an open end opening toward the container exterior. A through-hole is at the closed end of the straight portion. A projection on a closing plug and slidably inserted to the straight portion is slidably inserted to the through-hole. States are switchable between open and closed states in which the outflow channel is opened and closed by the closing plug and the projection is positioned in the through-hole or projects from the through-hole.
US11207850B2	Method for conditioning a load bearing surface and a surface formed thereby A method for conditioning a load bearing surface includes positioning an oriented polymeric membrane in a mount and applying a force to the polymeric membrane so as to create a stress in the membrane. The stressed membrane is heated to a temperature no less than about a temperature that the load bearing surface is expected endure in use. The membrane is maintained at the temperature for a first period of time sufficient to heat the entirety of the membrane and the it is cooled while maintaining the stress on the membrane. Following a predetermined cool down period, the applied stress is removed for availability of the end use product. A seating surface for use in a vehicle that is subjected to an elevated temperature is also disclosed.
US11207849B2	Computer controlled system for constructing an architectural component from an architectural material and a method for manufacturing such architectural component with the computer controlled system A method and system for constructing an architectural component from a three-dimensional form, the system including a movable support table for supporting and moving a three-dimensional form, a multi-task robotic arm having a base end configured for controlled movement along a path proximate the support table and a distal end configured to extend, translate, and/or rotate relative to the base and to include an end effector for applying successive layers of material onto a form on the support table, optionally, a linear rail to which said base is attached, and a computer processor for controlling a sequence of movements of the support table, the base, and the distal end of said multi-task robotic arm, and for controlling application of material to the three-diniensional form to form an architectural component of a predetermined shape and dimension.
US11207847B2	Air cushion inflation machine A machine for converting two different types of webs of inflatable material to two different types of inflated cushioning material includes an inflation arrangement, a sealing arrangement, and a tensioning device. The inflation arrangement is configured to provide air at a lower pressure to a first web of a first type of inflatable material to inflate the first type of inflatable material, and to provide air at a higher pressure to a second type of inflatable material to inflate the second type of inflatable material. The inflation arrangement includes a guide pin configured to the first and second webs and align the first and second webs on the machine. The sealing arrangement is configured to seal the first type of inflatable material and the second type of inflatable material to create the two different types of inflated cushioning material. The tensioning device is configured to provide a lower tensioning force to the first web as the first web moves between the inflation arrangement and the sealing arrangement, and to provide a higher tensioning force to the second web as the second web moves between the inflation arrangement and the sealing arrangement.
US11207846B2	Device and method for bonding fuel cell part A bonding device of a fuel cell part is disclosed. The bonding device of the fuel cell part may bond an upper gas diffusion layer and a lower gas diffusion layer to top and bottom surfaces of an MEA base material through adhesive layers, while disposing the MEA base material between the upper gas diffusion layer and the lower gas diffusion layer, and may include: a lower die that supports the MEA base material, the upper gas diffusion layer, and the lower gas diffusion layer to be bonded with each other; an upper die installed in an upper side of the lower die; and an ultrasonic wave vibration source that is installed to be capable of moving in a vertical direction at opposite sides of the upper die, compressing the upper gas diffusion layer, and applying ultrasonic wave vibration energy to the adhesive layer.
US11207845B2	Inductive thermo-crimping apparatus An inductive thermo-crimping apparatus is provided, which is provided for crimping a crimping body which is formed by the contact of the connecting body and the to-be-joined member. The inductive thermo-crimping apparatus includes a driving part, a stamper part, and a heating part, the driving part is connected to the stamper part, and the heating part is fixedly connected to the driving part. After the heating part is activated, the crimping body is disposed on the heating part. The heating part includes an inductive heating coil. The inductive heating coil surrounds in the heating part. The inductive heating coil is provided for heating the crimping body to soften the crimping body, in which the driving part is provided for driving the stamper part to press the soften crimping body, so that the connecting body and the to-be-joined member is crimped and to form a rigid crimping body after cooling. The present invention utilizes the coil with an alternative current to heat the crimping body by an electromagnetic induction, so that the process of the crimping technology is convenient and fast.
US11207841B2	Methods and systems of three dimensional printing Embodiments of the present disclosure provide for systems and methods of three dimensional printing including a precursor build material comprising a hydrogel precursor and a support material, wherein the precursor build material has a gel-like state when a stress applied to the precursor build material is less than a yield stress, wherein the precursor build material has a free-flow state when the stress applied to the precursor build material is above the yield stress, wherein when the stress applied to the precursor build material changes from above the yield stress to below the yield stress, the precursor build material returns to the gel-like state.
US11207839B2	Support material formulation and additive manufacturing processes employing same Novel support material formulations, characterized as providing a cured support material with improved dissolution rate, while maintaining sufficient mechanical strength, are disclosed. The formulations comprise a water-miscible non-curable polymer, a first water-miscible, curable material and a second, water-miscible material that is selected capable of interfering with intermolecular interactions between polymeric chains formed upon exposing the first water-miscible material to curing energy. Methods of fabricating a three-dimensional object, and a three-dimensional object fabricated thereby are also disclosed.
US11207837B2	Method and control command generating unit for an automatic generation of control commands of an additive layer-wise building device A method for providing control commands for producing a number of three-dimensional objects by an additive layer-wise building device. The method can include a step of providing a computer-based model of the number of objects that geometrically describes the objects, a step of modifying the computer-based model such that for the geometric description of the number of objects a location is defined as a common origin of coordinates, and a step of generating control commands for a set of control commands for controlling the production of the number of objects by the additive layer-wise building device on the basis of the modified computer-based model.
US11207834B2	Selective laser sintered fused deposition printing A method of additive manufacturing of an object includes directing laser energy from a laser to a region for material deposition, extruding material using an extruder at the region of material deposition, sensing temperature within the region of the material deposition, and electronically controlling the laser energy using the temperature so as to sufficiently heat the region for material deposition prior to extruding the material to increase strength of the object.
US11207831B2	3D printed core-shell filament and method of 3D printing a core-shell filament A 3D printed core-shell filament comprises an elongated core radially surrounded by an outer shell with a barrier layer in between, where the elongated core comprises a ductile polymer and the outer shell comprises a stiff polymer having a Young's modulus higher than that of the ductile polymer. A lightweight lattice structure may comprise a plurality of the 3D printed core-shell filaments deposited in layers.
US11207828B2	Three-dimensional printer A three-dimensional printer comprising means for build material, a printer carriage and a curtain. The means for depositing the build material deposits same on a printing zone and/or on one or more build material layers deposited on the printing zone. The printer carriage is to move along a first axis over the printing zone and comprises means for treating the build material. The curtain is attached to a first side of the printer carriage with a first side of the curtain and/or configured to move along with the printer carriage such that the curtain covers at least an area of the print zone, wherein the area varies dependent on the moving of the printer carriage over the print zone.
US11207825B2	Localized heating to improve interlayer bonding in 3D printing The present disclosure provides methods for printing at least a portion of a three-dimensional (3D) object, comprising receiving, in computer memory, a model of the 3D object. Next, at least one filament material from a source of the at least one filament material may be directed towards a substrate that is configured to support the 3D object, thereby depositing a first layer corresponding to a portion of the 3D object adjacent to the substrate. A second layer corresponding to at least a portion of the 3D object may be deposited. The first and second layer may be deposited in accordance with the model of the 3D object. At least a first energy beam from at least one energy source may be used to selectively melt at least a portion of the first layer and/or the second layer, thereby forming at least a portion of the 3D object.
US11207824B2	Localized heating to improve interlayer bonding in 3D printing The present disclosure provides methods for printing at least a portion of a three-dimensional (3D) object, comprising receiving, in computer memory, a model of the 3D object. Next, at least one filament material from a source of the at least one filament material may be directed towards a substrate that is configured to support the 3D object, thereby depositing a first layer corresponding to a portion of the 3D object adjacent to the substrate. A second layer corresponding to at least a portion of the 3D object may be deposited. The first and second layer may be deposited in accordance with the model of the 3D object. At least a first energy beam from at least one energy source may be used to selectively melt at least a portion of the first layer and/or the second layer, thereby forming at least a portion of the 3D object.
US11207823B2	Removable extruder cap A cap for an extruder of a three-dimensional printer is removeable and replaceable on the hot end of the extruder, e.g., for cleaning or other maintenance of the cap or extruder. The cap may be formed of a polymer having a lower thermal conductivity than the hot end of the extruder such that the cap forms a thermal barrier between the hot end of the extruder and an external environment. Further, the cap may protect the hot end of the extruder from damaging contact with deposited build material (e.g., spatters) as well as other undesirable contact during a three-dimensional printing process.
US11207821B2	Method of making 3D tube and 3D tube made thereby A method of making a 3D tube and the 3D tube made thereby. The method comprises: inserting a deflated pre-formed bladder into the 3D tube; and inflating the pre-formed bladder to deform the 3D tube and make the 3D tube have a substantially similar shape as that of the pre-formed bladder inflated.
US11207819B2	Trim part for a motor vehicle, as well as method and device for its manufacture The present disclosure pertains to a trim part for a motor vehicle that comprises: a carrier; and a decorative material applied onto an upper surface of the carrier, wherein the decorative material comprises a printed thermoplastic film; and wherein the trim part is shaped by a deep-drawing process and a grain or impression is produced on the visible side of the film, which faces away from the carrier, by the deep-drawing process. A method and a device for manufacturing the trim part is also proposed.
US11207814B2	Method of manufacturing an escalator handrail A method of manufacturing an escalator handrail which has a composite material including a metallic steel wire and a thermoplastic resin, said metallic steel wire having a center elemental wire and a plurality of strands placed so as to surround the center elemental wire, including: a preheating step of heating the metallic steel wire; a composite-material forming step of integrating the metallic steel wire heated in the preheating step with the thermoplastic resin in a molten state to thereby form the composite material; and a cooling step of cooling the composite material formed in the composite-material forming step.
US11207810B2	Liquid additive delivery system and methods for ensuring substantially only a liquid is disposed within a container Methods, apparatuses and systems are disclosed including a method of filling a container with substantially only a liquid. The method can include the removal of a gas from the container prior to, during or after the filling of the container with the liquid. According to one embodiment, the container includes an inner liner and a lid. The method includes providing a volume defined by at least the inner liner and the lid of the container. In such embodiment, the liquid can initially be contained within a first portion of the volume and a remaining portion of the volume can contain a gas. The method can include removing substantially all the gas from the volume via one or more ports that communicate with the volume while retaining substantially only the liquid within the volume.
US11207805B2	Process for manufacturing a resulting pharmaceutical film The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
US11207800B2	Method and installation for producing rotomolded products The invention relates to a method for producing rotomolded products, and to an installation for carrying out such a method. The method is characterized by the simultaneous use of a plurality of spherical receptacle members, each without a dedicated rotary drive, each of which containing at least one molding die that is suppliable with raw material, and by the simultaneous use of a plurality of processing devices which are operated in a mutually independent manner, each for carrying out at least one of a plurality of production steps, using in each case one of the spherical receptacle members, wherein a plurality of processing devices which are configured as rotating stations are used in a temporally parallel or temporally overlapping manner, and/or wherein a plurality of processing devices which are configured as cooling stations are used in a temporally parallel or temporally overlapping manner, and/or wherein a plurality of processing devices which are configured as supply stations are used in a temporally parallel or temporally overlapping manner, and/or wherein a plurality of processing devices which are configured as retrieval stations are used in a temporally parallel or temporally overlapping manner, and wherein the spherical receptacle member conjointly with the content thereof and without the rotary drive is in each case retrieved from the processing device which has just terminated a processing step, said spherical receptacle member thereafter being fed to a processing device that is immediately vacant for the respective next processing step.
US11207799B2	Pelletization gas guide Polymer pellets are formed using laminar gas flow within a downstream gas conduit, as may be implemented consistent with one or more embodiments herein. A gas channel directs gas to an outlet of a polymer extrusion mandrel via which a polymer melt is extruded. A downstream gas conduit extends away from the outlet of the polymer extrusion mandrel, and provides laminar gas flow along the polymer melt extending from the extrusion mandrel, and within the downstream gas conduit. Using this approach, laminar flow can be maintained along an initial portion of the polymer melt, and used to control the subsequent formation of pellets therefrom.
US11207794B1	Systems and methods for trimming powered cards and devices Cards may be manufactured in a lamination process, such that interior portions of the cards may be visible. Punch alignment queues within the card may be scanned by a punch machine and rendered onto a display of the punch machine. The punch alignment queues may be aligned with targets also rendered onto the display so that the card may be properly aligned within a punch machine to prepare the card for a trimming process. A Venturi system may temporarily adhere the card to a punch of the punch machine while the punch is engaged with a die to trim the card. The cutting surface of the die may be offset with respect to a surface of the punch, so that the card may be sequentially trimmed along a perimeter of the card.
US11207791B2	System for material application and cutting A system comprising a material decorating and cutting device used with an alignment apparatus to simultaneously cut and deposit decorating material on arts and crafts materials surfaces such as sheet stock. The cutting device contains a reservoir with decorating material such as paint, glue, ink, pigment, or three-dimensional material such as wax. The cutting device has a tip with a nib and a blade. The nib facilitated the transfer of decorating material to a target material such as paper or wood while the blade cutting edge cuts the target material. The alignment apparatus provides for continuous decorating and cutting on a surface. The system provides an efficient, fun, and safe way to participate in arts and crafts activities.
US11207786B1	Concentric suction cup array for end-of-arm tool An end-of-arm-tool attachment deploys gripper arms to help stabilize picked items. The arms rotate around the lower body of the tool and, depending on the size of the item, will either support the item from below or help reduce swinging by applying pressure to the sides/top. When not in use, the arms are stowed on the upper body of the tool to minimize potential for collision and to provide a smaller profile for maneuverability.
US11207785B2	Tool changer and tool change system A tool changer is included in a manipulator of a robot and selectively fastens to a tool by a magnetic force. The tool changer may include a housing; an inner core embedded in the housing; a coil wound around the inner core, wherein a current is applied to the coil; a pair of connecting cores connected to both ends of the inner core, protruding from the housing to the tool, and inserted into a connecting groove of the tool; a switch configured to regulate the current applied to the coil; and a controller configured to open or close the switch according to a set frequency.
US11207784B2	Hand-held robot operating device combination comprising a basic-control position sensor A hand-held robot operating device combination has: an autonomous safety-related basic control device that includes a housing, a safety-relevant switching means on the housing, and a communication device for connecting the autonomous safety-related basic control device for control purposes to a controller of a robot; an autonomous mobile terminal that includes a terminal controller and at least one terminal position sensor designed to sense positional data in respect of the autonomous mobile terminal in at least one of the degrees of freedom thereof; and a holder designed to mechanically connect the autonomous safety-related basic control device to the autonomous mobile terminal in a manually detachable combined arrangement so as to form the hand-held robot operating device combination; the autonomous safety-related basic control device includes at least one basic-control position sensor which is designed to sense positional data in respect of the autonomous safety-related basic control device in at least one degrees of freedom thereof.
US11207776B2	Device, system, method, and machine-readable medium for conveying an industrial robot A system for conveying an industrial robot includes: a control module, at least one automatic guided vehicle, and at least one electromagnetic base. An industrial robot is installed each electromagnetic base, which may attract a metallic plate fixed to the ground, thereby fixing the industrial robot installed on the electromagnetic base. An electromagnetic base is configured to, according to a first control instruction sent by the control module, stop attracting the metallic plate so that the industrial robot is movable. An automatic guided vehicle is configured to, according to a second control instruction sent by the control module, convey, to a target position, the industrial robot installed on the electromagnetic base that has stopped attracting the metallic plate. Finally, an electromagnetic base is further configured to, according to a third control instruction sent by the control module, attract the metallic plate fixed to the ground in the target position.
US11207772B2	Insulated screwdriver An insulated screwdriver includes: an insulator, a first metal sleeve, a second metal sleeve, an insulated sleeve, and a handle. The insulator has a first connecting portion and a second connecting portion. The first metal sleeve is disposed on the first connecting portion of the insulator. The second metal sleeve is disposed on the second connecting portion of the insulator, and the second metal sleeve and the first metal sleeve are insulated. The insulated sleeve covers the insulator, the first metal sleeve, and the second metal sleeve. The handle has an accommodating hole for accommodating the insulated sleeve. According to the insulated screwdriver of the present invention, because the first metal sleeve and the second metal sleeve are insulated, there is no electric shock danger for a user, and safety in use of the insulated screwdriver of the present invention may be improved.
US11207769B2	Hydraulic hammering device A hydraulic hammering device includes a piston front chamber and a piston rear chamber defined between an outer circumferential surface of the piston and an inner circumferential surface of the cylinder and disposed separately from each other at front and rear, respectively, in an axial direction. A switching-valve mechanism drives the piston by switching at least one of the piston front chamber and the piston rear chamber into communication with at least one of a high pressure circuit and a low pressure circuit. An acceleration piston is disposed behind the piston and is configured to come into contact with the piston during a retreat stroke thereof to urge the piston forward, in which a timing where the acceleration piston itself starts to come in contact with the piston is set to be earlier than a timing where the piston is braked by the switching-valve mechanism.
US11207768B2	Fastener driving machine A fastener driving machine provided with a mechanism to lubricate pins or racks is realized. A fastener driving machine includes a driver blade, pins, and a lubricant feeding mechanism. The driver blade can reciprocate in a first direction and a second direction opposite to each other, and hits a fastener when the driver blade moves in the first direction. The pins respectively engage with racks provided on the driver blade to move the driver blade in the second direction. The lubricant feeding mechanism supplies lubricant to the racks and the pins.
US11207761B2	Socket for driving asymmetric fastener heads A socket having an offset drive keyway for transmitting torque to asymmetric fastener heads to facilitate their rotation by applying torque across the fastener end to minimize stress on the fastener end-fastener shaft joint.
US11207758B2	Printing a chemical mechanical polishing pad A method of fabricating a polishing layer of a polishing pad includes successively depositing a plurality of layers with a 3D printer, each layer of the plurality of polishing layers deposited by ejecting a pad material precursor from a nozzle and solidifying the pad material precursor to form a solidified pad material.
US11207757B2	Composition for polishing pad, polishing pad and preparation method of semiconductor device In the composition according to an embodiment, the weight ratio of toluene 2,4-diisocyanate in which one NCO group is reacted and unreacted toluene 2,6-diisocyanate in the urethane-based prepolymer is adjusted, whereby such physical properties as gelation time can be controlled. Thus, the polishing rate and pad cut rate of a polishing pad obtained by curing the composition according to the embodiment may be controlled while it has a hardness suitable for a soft pad, whereby it is possible to efficiently manufacture high-quality semiconductor devices using the polishing pad.
US11207745B2	Weld wheel cleaning system A weld wheel cleaning system is provided to clean or remove a layer of embedded material and other debris produced from welding from the working surface of a weld wheel. Such a weld wheel cleaning system includes a cleaner with an abrasive material positioned on an outer surface of the cleaner. The cleaner is positionable adjacent to the weld wheel such that the abrasive material is aligned with the working surface of the weld wheel. An actuator can be used to selectively actuate the cleaner with a force sufficient to remove the layer of embedded material from the working surface of the weld wheel with the abrasive material. The debris from the cleaner can be removed by a vacuum.
US11207740B2	Method for producing an internal combustion engine A method for producing an internal combustion engine, includes the steps of providing a cylinder comprising a cylinder wall, wherein a surface of the cylinder wall has a structure which is designed and formed such that it can be penetrated by a coating; generating at least one barrier region by way of at least regional machining of the structure such that the coating cannot penetrate into the structure; and applying a coating to the cylinder wall, which coating does not penetrate into the structure in the at least one barrier region.
US11207738B2	Machine tool driven in an oscillating manner An oscillatingly driven machine tool having a housing in which a motor with a motor shaft is received, on which an eccentric element is accommodated, with a spindle head, with a tool spindle that is rotatably mounted about its longitudinal axis in the spindle head, on which a coupling element is non-rotatably received, which cooperates with the eccentric element for generating a movement of the tool spindle which oscillates about its longitudinal axis such that, in addition to the oscillating movement, a differing, superimposed movement is introduced into the coupling element.
US11207737B2	Inline tool holders An inline tool holder including a shaft collar, a mounting plate, a first enclosure, and a second enclosure. The mounting plate is concentrically arranged around the shaft collar and includes a first surface, a second surface, and an attachment mechanism. The first enclosure is removably coupled to the first surface of the mounting plate and the second enclosure is removably coupled to the second surface of the mounting plate. The attachment mechanism of the mounting plate extends radially beyond an outer edge of both the first enclosure and the second enclosure.
US11207735B2	Apparatus and method for the additive manufacturing of three-dimensional structures An apparatus for the additive manufacturing of three-dimensional structures from a material that is to be solidified by way of location-selective solidification thereof as a result of light-induced chemical and/or physical processes in the material includes a laser source for producing a laser beam, a focusing optical unit for focusing the laser beam so as to form a laser focus, and a beam-splitter optical unit for splitting the laser beam into at least two partial laser beams. The laser source, the focusing optical unit and the beam-splitter optical unit are arranged such that the laser beam, starting from the laser source, passes first through the focusing optical unit and then through the beam-splitter optical unit and the partial laser beams finally are each directed to different locations on the material that is to be solidified.
US11207734B2	Fusing of metallic particles According to an example, an apparatus may include a processor and a memory on which is stored instructions. The instructions may cause the processor to control at least one energy source to apply energy at a certain low energy level onto a layer of metallic particles, in which the metallic particles have micron-level dimensions, and in which application of the certain low energy level may sinter the metallic particles and may cause formation of physical connections between adjacent ones of the metallic particles. The instructions may also cause the processor to control the at least one energy source to apply energy at a certain high energy level onto the layer of metallic particles, in which application of the certain high energy level energy may melt and fuse the sintered metallic particles.
US11207732B2	Integrated method for manufacturing high-temperature resistant thin-walled component by preforming by laying metal foil strip An integrated method for manufacturing a high-temperature resistant thin-walled component by preforming by laying a metal foil strip. The integrated manufacturing method includes: designing a preform, preparing a support die, determining a thickness of a foil strip, determining a width of the foil strip, developing a laying process, laying an A foil strip and a B foil strip, obtaining an AB laminated preform, bulging the preform, performing a reactive synthesis and a densification process of a bulged component, and performing a subsequent treatment of the thin-walled component. Various embodiments obtain an integral thin-walled preform with a complex structure, a uniform wall thickness and a shape close to the final part by continuously laying a metal foil strip with an appropriate width.
US11207725B2	Hot forging die and manufacturing process for forged product using the same, and manufacturing process for hot forging die To provide a hot forging die made of a Ni-based superalloy, which is free from any deteriorations in working environment and die shape during hot forging in the air, and also provide a manufacturing process for a forged product using the same and a manufacturing process for a hot forging die. The hot forging die includes: a base body made of a Ni-based superalloy consisting of, by mass, 10.3 to 11.0% of W, 9.0 to 11.0% of Mo, and 5.8 to 6.8% of Al and balance of Ni with inevitable impurities; and a coating layer of inorganic material that is formed on at least one of a forming surface and a side surface of the die and contains 30 mass % or more in total of one or more of Si, Cr, and Al out of Si and metal elements.
US11207723B2	Straightening apparatus for metal products and method to replace at least one straightening roll of said apparatus Apparatus for straightening metal products comprising:at least one rotation shaft on which at least one straightening roll is installed in a selectively removable manner;a first structure provided with at least a first support member configured to hold and support a first end of the rotation shaft;a second structure provided with at least a second support member configured to selectively support and hold a second end, opposite the first end, of the rotation shaft;a movement member configured to move the second structure toward/away from the first structure and to allow the installation or removal of the straightening roll from the rotation shaft.
US11207722B2	Systems and methods for manufacturing a ring from a metal sheet A method for manufacturing a ring includes clamping a first region of a metal sheet against a mandrel, and, while the first region of the metal sheet is clamped against the mandrel, bending the metal sheet around the mandrel to join opposite end faces of the metal sheet and form the ring shaped to the mandrel. A system for manufacturing a ring from a metal sheet includes (a) a mandrel having a ring-shaped surface, (b) a clamp facing the ring-shaped surface and configured to clamp a first region of a metal sheet to the mandrel, and (c) a plurality of dies configured to bend the metal sheet around the mandrel, while the clamp clamps the first region to the mandrel, to join opposite end faces of the metal sheet and form a ring shaped to the ring-shaped surface.
US11207720B2	Roll body for a hydrostatic rolling tool and hydrostatic rolling tool with the roll body A roll body for a hydrostatic rolling tool includes a center, an axis of rotation running through the center, and a machining zone for rolling a workpiece. The roll body is rotatable about the axis of rotation and the machining zone has a working profile line formed in a cross-section of the roll body. The working profile line has a first working arc extending around a first machining center and a second working arc extending around a second machining center. The first machining center is arranged offset to the center, and the second machining center is arranged offset to the center and offset to the first machining center. In an example embodiment, the roll body has a parallel to the axis of rotation, the first machining center lies in the cross-section on the parallel, and the second machining center lies in the cross-section on the parallel.
US11207714B2	Biological cleanup kit The present disclosure relates to a kit for cleaning biological fluids from a surface. The kit comprises at least one protective article of clothing, absorbent powder, a trash bag, surface sanitizer, an absorbent towel, a scraper, a handle, and a dustpan. The dustpan is configured to be securely coupled to the handle. The dustpan has a lid and a base and can alternate between an open position and a self-sealing closed position. In the closed position the base and lid define an interior volume having a height along a y-axis, a width along an x-axis, and a depth along a z-axis. An adhesive strip is coupled to a lip of the dustpan and is configured to interact with a surface and temporarily engage the dustpan with the surface. The absorbent powder is a mixture of a super absorbent polymer and perlite.
US11207713B2	Disc for use in disc screen A disc for use in a disc screen is disclosed. The disc includes a longitudinal disc axis and a hub extending a length along the longitudinal disc axis. The hub further includes a hub surface and a helical ridge structure extending away from the hub surface and twisting about the longitudinal axis at least 360 degrees. A cross-section of the hub taken perpendicularly to the longitudinal disc axis is non-circular.
US11207708B2	Handheld fluid applicator An applicator for introducing a fluid to a plant includes a first arm and a second arm pivotally connected to one another at one end. The other ends are spaced apart to receive the plant therein when the applicator is in a rest position and are driven together upon pivoting of the arms to place the applicator in an application position. A fluid injector is mounted on the first arm and includes an injector body and a diaphragm defining a plurality of channels. The diaphragm includes a pliable dome defining a reservoir to receive the fluid and a plurality of applicator nodes. A respective applicator node is positioned near a terminus of each channel. A driving member engages the pliable dome when the applicator is pivoted to the application position. The pliable dome is then compressed by the driving member to direct the fluid through the plurality of channels.
US11207705B2	Mask and method of manufacturing mask assembly including the same A mask and a method of manufacturing a mask assembly, the mask including a body, and the body including one end and another end facing each other in a length direction and having a first surface and a second surface facing each other in a thickness direction; and a pattern region between the one end and the other end, the pattern region including a plurality of pattern holes and a plurality of ribs between the plurality of pattern holes, wherein a curl value of the mask, which is defined as a shortest distance from a plane tangent to a center of the body to the one end or the other end of the body, is 1,000 μm to 4,000 μm.
US11207704B2	Installation for spraying a fluid and related methods An installation for spraying a fluid comprising a fluid circulation circuit including a sprayer capable of spraying the fluid, a pump and a circulation pipe for the fluid, the pump being suitable for injecting the fluid into the circulation pipe, the circulation pipe being configured to guide the fluid from the pump to the sprayer, the installation further including at least one injector configured to inject a liquid separate from the fluid into the circuit, wherein the injector is configured to compare a total volume of liquid injected into the circuit to a predetermined volume, and to stop the injection when the total volume of injected liquid is equal to the predetermined volume.
US11207703B2	Discharge pump A discharge pump (2) includes a stationary suction part (A) which includes a cylinder (A1) having a first check valve (V1) at a lower part thereof, and a mounting member (A3) to be mounted on a neck part of a container body, and an actuating member (B) which includes a discharge head (B4), a stem (B2), a piston guide (B1), and an annular piston (B3), a second check valve (V2) being formed between a lower end part of the annular piston and a lower part of the piston guide, and in a fitting part between the stem and the piston guide, an engaging unit (E) which is configured to restrict the stem and the piston guide from idling each other when screwing of the actuating member to the stationary suction part is released and the actuating member is raised from the stationary suction part is provided.
US11207697B2	Adjustable flow nozzle system Various embodiments for an adjustable flow nozzle system having a manifold with a plurality of adjustable flow nozzles in which the flow rate of each adjustable flow nozzle may be individually adjusted are described herein.
US11207694B2	Packaging dry leaves in sealed capsules A system for packaging tea in a sealed casing. the system includes a machine for breaking dried tea leaves, said machine comprising an inlet for supplying dried tea leaves, an outlet for releasing the broken tea leaves, and at least one breaker device including a first breaker member and a second breaker member that can be removed relative to the first breaker member, said first and second breaker member being configured to bend the dried tea leaves until they break.
US11207692B2	Reagent cartridge Provided is a reagent cartridge configured to be set in a genetic testing device and the reagent cartridge includes a plurality of reagent containers in which a reagent is filled, and a holder formed with a plurality of opening parts in which the reagent containers are loaded and configured to hold the reagent containers loaded in the opening parts, in which the holder holds the reagent containers with an allowance in a vertical direction in a state in which the reagent cartridge is set in the genetic testing device.
US11207689B2	Cartridge for extracting nucleic acid There is provided a cartridge for nucleic acid extraction comprising: a first body having a plurality of chambers in which ports are formed at the bottom; a second body coupled to a lower region of the first body; and a piston disposed rotatably in the centers of the first body and the second body and having a port formed at the bottom thereof; and characterized in that the cartridge comprises a plurality of flow paths formed on the upper region of the second body, one end overlapping the port of the piston and the other end overlapping the port of the first body.
US11207684B2	Method and system for studying biological cells A method of manipulating and/or investigating cellular bodies (9) is provided. The method comprises the steps of: providing a sample holder (3) comprising a holding space (5) for holding a fluid medium (11); providing a sample (7) comprising one or more cellular bodies (9) in a fluid medium (11) in the holding space (5); generating an acoustic wave in the holding space exerting a force (F) on the sample (7) in the holding space (5). The method further comprises providing the holding space (5) with a functionalised wall surface portion (17) to be contacted by the sample (7) and the sample (7) is in contact with the functionalised wall surface portion (17) during at least part of the step of application of the acoustic wave. A system and a sample holder (3) are also provided.
US11207682B2	Flow distributor A distributor is described for distributing a fluid flow from a smaller to a more broad fluid flow. It comprises a fluid input and a plurality of fluid outputs, and a channel structure in between the fluid input and the plurality of fluid outputs. The channel structure comprises alternatingly bifurcating channel substructures and common channel substructures wherein the substructures are arranged so that fluid exiting different channels from a bifurcating channel substructure mixes in a subsequent common channel substructure, and whereby fluid channels of the bifurcating channel substructure are arranged such that these do not contact the subsequent common channel substructure at the edges thereof.
US11207679B2	DNA extraction device A DNA extraction device may include a substrate, at least one first side channel electrode, at least one second side channel electrode, optionally, at least one elongate central channel electrode, and a voltage source connected between the electrodes. The substrate defines an elongate central channel defining a major axis. A width of the elongate central channel is greater than its depth, and its depth is less than about 15 times a diameter of a cell to be introduced in the elongate central channel. The substrate also defines first and second side channels adjacent to the elongate central channel on opposite sides of the major axis. The substrate further defines first and second trapezoidally shaped connecting channels connecting the elongate central channel and the first and second side channels, respectively. The smaller parallel sides of the first and second trapezoidally shaped connecting channels open to the respective side channels.
US11207677B2	Devices, systems, and methods for detecting substances A microfluidic device for the detection of drugs, explosives, chemical warfare, or other substances which is able to directly accept a swab into the device for testing. This device additionally contains on-board reagents to perform colorimetric testing for threshold determination directly in the device. These features are useful in a wide array of situations, such as at security checkpoints, environmental monitoring, clinical analysis, which require testing completely unknown substances and therefore must test for multiple different substances in one test. This is especially useful for police and other law enforcement officials who often must use field-deployable platforms making accurate field-testing critical for safety.
US11207676B2	Lab-on-a-chip (LOC) for biomimetic bone remodeling analysis A lab-on-a-chip (LOC) for the biomimetic study of the multicellular interactions of bone cells includes a PDMS substrate and cap, which together form one or more wells that are fluidly coupled by tubes. The wells are configured to support various bone cells and related cellular support substrates therein, while the tubes allow conditioned medium (CM), including soluble signals, and various other co-factors to be communicated among the various wells. By controlling the configuration among and between various bone cells in the wells, the temporal and spatial limitations associated with traditional in vivo bone tissue models is removed. In addition, the LOC enables a particular research objective to be studied by allowing the user to configure the arrangement of the wells/tubes of the LOC, so as to control the manner in which bone cell soluble signals, bone cell contact, and bone cell matrix interaction interplay.
US11207674B2	Method of customizing a universal reagent cartridge with a lyophilized target-specific reagent Customization of a universal reagent cartridge with a lyophilized target-specific PCR component reagent is disclosed. The universal reagent cartridge includes multiple chambers populated with predetermined non-target-specific reagents therein. A custom reagent storage device that stores a lyophilized, target-specific reagent is provided and is configured to be end user insertable into the universal reagent cartridge to customize the universal reagent cartridge with the target-specific reagent.
US11207671B2	Mixtures for the adsorption of acidic gases The invention relates to mixtures containing basic anion exchangers and flow regulators, the use thereof for the adsorption of acidic gases and of carbon dioxide in particular, a process for continuous gas adsorption, and heat exchangers that contain the mixtures containing basic anion exchangers and flow regulators.
US11207664B2	Heterogeneous catalyst A heterogeneous catalyst comprising a support and a noble metal. The catalyst has an average diameter of at least 200 microns and at least 90 wt % of the noble metal is in the outer 50% of catalyst volume.
US11207663B2	Compositions and methods relating to molecular cerium-oxide nanoclusters Described herein are compositions and methods relating to molecular cerium-oxide nanoclusters. In an aspect, described herein are methods of synthesizing molecular cerium-oxide nanocluster compositions and compositions thereof. In an aspect, described herein are methods of scavenging reactive oxygen species utilizing molecular cerium-oxide nanoclusters as described herein. Also described herein are pharmaceutical compositions and methods of use. Pharmaceutical compositions as described herein can comprise a therapeutically effective amount of a compound (such as a composition comprising one or more molecular cerium-oxide nanoclusters), or a pharmaceutically acceptable salt of the compound, and a pharmaceutically acceptable carrier. Methods of treating oxidative stress are also described herein, comprising administering pharmaceutical compositions as described herein to a subject in need thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
US11207662B2	Mixed-metal oxide based catalysts One or more embodiments relates to a method of catalytically converting a reactant gas mixture for pollution abatement of products of hydrocarbon fuel combustion. The method provides substituted mixed-metal oxides where catalytically active metals are substituted within the crystal lattice to create an active and well dispersed metal catalyst available to convert the reactant gas mixture. Embodiments may be used with gasoline and diesel fueled internal combustion engine exhaust, although specific embodiments may differ somewhat for each.
US11207659B2	Method for preparing monolithic coated surfaces A carrier for adsorption a compound, comprising a support; and a shrink-fitted monolithic body attached to and surrounding at least a portion of the support. The monolithic body can be porous and configured to bind compounds in a solution either for the isolation or depletion of the compounds from the solution.
US11207647B2	Rotary shaft for processing foodstuffs, industrial device comprising such a rotary shaft, a method of manufacturing such a rotary shaft and a method for processing foodstuffs The invention relates to a rotary shaft for processing foodstuffs, the rotary shaft has a rotation axis and the rotary shaft comprises at least one tool which extends along the rotation axis. The tool has an airfoil profile such that the tool comprises a leading edge, a trailing edge, an upper surface and a lower surface. Further, the tool comprises at least one fluid channel between the mean camber line of the airfoil profile and the upper surface of the tool.
US11207644B2	Filter medium with improved backwashing durability, method for manufacturing same, and filter unit comprising same A filter medium is provided. The filter medium according to an embodiment of the present invention comprises a second support body and a nanofiber web layer which are sequentially stacked on each of both surfaces of a first support body, and is a filter medium having a flow path through which a filtrate filtrated in the nanofiber web flows in the direction of the first support body, wherein the nanofiber web has a basis weight of 30 g/m2 or less, the first support body has a basis weight of 250 g/m2 or more, and a thickness of 90% or more of the total thickness of the filter media. Accordingly, even in a backwash process performed at high pressure, as the shape, structural deformation, and damage of the filter medium can be minimized, the use period can be extended. In addition, as the flow path is smoothly secured at high pressure applied at the time of filtration and/or backwashing, the filtration water is quickly discharged to the outside from the inside of the filter medium or the backwashing efficiency is very excellent, and accordingly it is possible to be applied in various ways in various water treatment fields.
US11207642B2	Catalyst article and the use thereof for filtering fine particles The present invention provides catalyst article, and its use in an exhaust system for internal combustion engines, is disclosed. The catalyst article catalyst article comprises: a substrate which is a wall-flow filter having an inlet end and an outlet end and an axial length L therebetween, a plurality of inlet channels extending from the inlet end and a plurality of outlet channels extending from the outlet end, wherein the plurality of inlet channels comprise a first catalyst composition extending from the inlet or outlet end for at least 50% of L and the plurality of outlet channels comprise a second catalyst composition extending from the outlet or inlet end for at least 50% of L, wherein the first and second catalyst compositions overlap by at most 80% of L, and wherein the first and second catalyst compositions each independently comprise a particulate oxygen storage component (OSC) having a first D90 and a particulate inorganic oxide having a second D90 and: i) the first D90 is less than 1 micron and the second D90 is from 1 to 20 microns; or ii) the second D90 is less than 1 micron and the first D90 is from 1 to 20 microns.
US11207640B2	System and method for adjusting carbon dioxide concentration in indoor atmospheres An electrochemical device suited to modifying a carbon dioxide concentration in an interior space includes a cathode chamber with an inlet which receives a feed gas containing carbon dioxide. A reduction catalyst layer in the cathode chamber reduces carbon dioxide in the gas to form an ionic carrier species. An anode chamber with an outlet outputs a gas comprising carbon dioxide. A solid electrolyte membrane spaces the anode chamber from the cathode chamber and transports the ionic carrier species between the cathode chamber and the anode chamber. The membrane includes an ionic liquid. An oxidation catalyst layer in the anode chamber oxidizes the ionic carrier species to form carbon dioxide. A voltage source provides a voltage difference across the membrane.
US11207637B2	Gas separating system Separation efficiency of a gas in a gas separator mounted on a vehicle is improved. The gas separation system mounted on the vehicle provided with an internal combustion engine includes the gas separator configured to separate a predetermined component in the gas under the existence of water, a first passage connected to the gas separator so as to introduce an atmosphere into the gas separator, and a second passage connecting between an exhaust passage of the internal combustion engine and the first passage so as to introduce exhaust gas of the internal combustion engine into the gas separator.
US11207636B2	Membrane permeate recycle system for use with pressure swing adsorption apparatus A system that is used for the treatment of a net gas stream is disclosed. The system includes a compressor to produce a compressed gas stream from a net gas stream. The compressor is connected to a pressure swing adsorption unit where the net gas stream is separated to produce a hydrogen product stream and a tail gas stream. Tail gas stream from the pressure swing adsorption unit is sent to a first membrane unit to produce a first permeate stream and a first non-permeate stream. A portion of the tail gas stream is sent to a second membrane unit to produce a second permeate stream and a second non-permeate stream.
US11207635B2	Process for dehumidifying moist gas mixtures A process and an apparatus for dehumidifying a moist gas mixture are provided. The apparatus for dehumidifying a moist gas mixture can be used and in the process. The absorption medium used in the process and the apparatus is also provided.
US11207627B2	Filter assembly and scrubber section for a continuous miner A filter assembly includes a first screen, defining a first flow passageway, a second screen, defining a second flow passageway, and a third screen defining a third flow passageway. The second screen is positioned between the first screen and the third screen. The first flow passageway is aligned with the third flow passageway and the second flow passageway is offset from the first flow passageway and the third flow passageway.
US11207617B2	Shearing member and filtration device A shearing blade is used in a filtration device including a filtering element having a filtering surface and a plurality of filter pores provided on the filtering surface for filtering unfiltered fluid introduced into a primary side, a scraper abutting the filtering element for cleaning the filtering surface by rotating in a rotational direction, a pillar provided in the primary side to which the scraper is attached, and a tube body. The front end portion of the shearing blade is at least disposed between the filtering surface and a circle defined by the outer circumferential end of the pillar in the radial direction, and the distance between the front end portion and the filtering surface in the radial direction is shorter than the distance between the rear end portion of the shearing blade and the filtering surface in the radial direction.
US11207610B2	Amusement device with writing/drawing surface An amusement device includes a housing and a light unit positioned on the housing. A mounting ring is rotatably positioned on the housing, encircling the light unit. The amusement device also includes a rotatable, dome-shaped cover sized and shaped so as to be mounted on the mounting ring for conjoint rotation therewith. The rotatable, dome-shaped cover has an outer hemispherical surface adapted for covering the light unit and for placement of markings thereon. The light unit is adapted to illuminate the rotatable cover and any markings placed thereon. A motor unit is positioned in the housing for rotating the mounting ring and hence the cover and any markings thereon. Optionally, the amusement device may be provided with a stationary, dome-shaped cover having an outer hemispherical surface which is sized and shaped so as to be positioned over the rotatable cover and in spaced relationship thereto. The outer hemispherical surface of the stationary cover is adapted to receive markings thereon, whereby any markings placed on the rotatable cover are rotatable relative to any markings placed on the stationary cover upon rotation of the rotatable cover.
US11207609B2	Magnetic toy construction block with ring-type magnet A magnetic toy construction block has an interior configured to house a radially magnetized ring magnet, which is rotatably supported within the block by a pair of pedestals extending into the interior of the block from opposite ends thereof. The positions of the poles of the ring magnet are variable relative to the sides of the block in response to the rotation of the ring magnet.
US11207604B1	Systems and methods to incentivize particular in-game user behaviors and particular user activities within an online game Systems and methods to enable users to incentivize particular in-game user behaviors and particular user activities within an online game are disclosed. Exemplary implementations may: effectuate presentation of an incentive interface that enables a first user to define a social agreement of a set of activities for a second user to perform and incentives for the set of activities that the second user can earn, and specify the second user to propose the social agreement to; effectuate presentation of the social agreement to the second user via an online gaming platform; receive an indication of acceptance to the social agreement; generate instructions to form the social agreement as a smart contract and transfer such to a decentralized ledger server for recordation; and receive indication of execution of the set of activities and, in responsive, provide the incentives to the second user.
US11207602B2	Information processing device and control method for executing a battle game including a field Instructions recorded on a non-transitory recording medium cause an information processing device that executes a battle game to execute the steps of storing different attribute information in association with each of at least two players; displaying a field including a plurality of regions, a predetermined event being set for each region, and attribute information being associable with each region; upon a player selecting at least one region from among the plurality of regions, executing processing for the event of the selected region; based on a processing result for the event, determining whether newly to associate the attribute information of the player with the selected region; and determining victory and defeat for the plurality of players based on at least one of a count, a total area, and a total volume of regions with which each piece of attribute information is associated.
US11207594B2	State stream game engine The present disclosure provides a state stream game engine for a video game application. The state stream game engines can decouple the simulation of a video game application from the rendering of the video game application. The simulation of the video game is handled by a simulation engine. The rendering of the video game is handled by a presentation engine. The data generated by the simulation engine can be communicated to the presentation engine 124 using a state stream.
US11207592B2	3D immersive method and device for a user in a virtual 3D scene A position and an orientation of a user in a virtual 3D scene is determined (22), an action is executed (24) in the virtual 3D scene for the user in function of the position and orientation of the user with respect to a given place, and a result of the action is outputted (25). For at least one event in the scene consisting in a presence of at least one determined virtual content, metadata linking the event(s) and at least one place of the event(s) are obtained (21). A given event and the given place linked by those metadata are determined (241), in function of the above position and orientation and of a relationship between that event and a user profile of the user. The action regarding the determined given event and place is executed.
US11207590B2	Video game controller A video game controller can automatically operate as a video game controller with audio capability and a video game controller without audio capability based upon a signal received via a switch in communication with an audio jack of the video game controller when a headset is coupled to the audio jack. Connection of the headset to the controller automatically causes video game audio to be communicated from the video game console to the headset via the controller. The video game audio is communicated at a default volume level to the headset upon coupling of the headset to the video game controller. The volume level of the audio communicated to the headset can be adjustable up or down via a directional pad of the video game controller while an audio control button on the video game controller is pressed.
US11207575B2	Golf club heads and methods to manufacture golf club heads Embodiments of golf club heads, golf clubs, and methods to manufacture golf club heads and golf clubs are generally described herein. In one example, a golf club head may include a body portion comprising a first material. The body portion may have a toe portion, a heel portion, a top portion, a sole portion, a back portion, a front portion having a face portion. The golf club head may include an interior cavity partially, substantially, or entirely filled with a first filler material and a second filler material. Other examples and embodiments may be described and claimed.
US11207574B2	Golf club head A golf club head includes a striking face, a crown and a sole. The crown and/or the sole includes an FRP member formed by a fiber reinforced plastic that contains a fiber and a matrix resin. The FRP member has an average flexural modulus of greater than or equal to 25 GPa. The fiber may contain a carbon fiber. The carbon fiber may have a tensile elastic modulus of greater than or equal to 300 GPa. The fiber may contain a metallic fiber. The FRP member may have a resin content of less than or equal to 40% by weight. The matrix resin may have a glass transition temperature of higher than or equal to 150° C.
US11207570B2	Dimple patterns for golf balls The present invention provides a method for arranging dimples on a golf ball surface in which the dimples are arranged in a pattern derived from at least one irregular domain generated from a regular or non-regular polyhedron. The method includes choosing control points of a polyhedron, generating an irregular domain based on those control points, packing the irregular domain with dimples, and tessellating the irregular domain to cover the surface of the golf ball. The control points include the center of a polyhedral face, a vertex of the polyhedron, a midpoint or other point on an edge of the polyhedron and others. The method ensures that the symmetry of the underlying polyhedron is preserved while minimizing or eliminating great circles due to parting lines.
US11207568B2	Dimple patterns for golf balls The present invention provides a method for arranging dimples on a golf ball surface in which the dimples are arranged in a pattern derived from at least one irregular domain generated from a regular or non-regular polyhedron. The method includes choosing control points of a polyhedron, generating an irregular domain based on those control points, packing the irregular domain with dimples, and tessellating the irregular domain to cover the surface of the golf ball. The control points include the center of a polyhedral face, a vertex of the polyhedron, a midpoint or other point on an edge of the polyhedron and others. The method ensures that the symmetry of the underlying polyhedron is preserved while minimizing or eliminating great circles due to parting lines.
US11207566B2	Balance trainer, mold assembly for making the same, and manufacturing process thereof A balance trainer having a dome and a base formed integrally is provided. Also, a mold assembly for manufacturing the balance trainer that has a dome mold, a girdle, and a cover is provided. The girdle is sleeved on the dome mold and the cover is fixed on the girdle and thereby a cavity is formed in the mold assembly. Furthermore, a manufacturing process of the balance trainer is also provided. The process has the following steps: preparing ingredients of the dome and the base; feeding the ingredients of the dome into the dome mold; fixing a membrane on the dome mold via the girdle; feeding the ingredients of the base; sealing the ingredients via the cover; and then rotational molding. With the process and the mold, the rotational molding step can mold two materials at the same time, so the product can have two parts with different hardness.
US11207564B2	Interactive exercise machine system with mirror display An interactive exercise system includes a mechanical support system and a display module held by the mechanical support system. A mirror element is attached to at least partially cover the display module. At least one movable arm is connected to the support system and at least one force-controlled component is connected to the mechanical support system. The force-controlled component can be graspable by a user and allows for a range of exercise types and programs.
US11207561B1	Portable pushup grips The present invention is described as one set containing a pair of pushup grips. Each grip includes a longitudinal hand support connected to two separate base supports. Each base support has a spring-loaded connection mechanism for rotation between a compact storage position and an active engaged position. The base supports are identical configurations, with a channel through the top of the length for the storage position, a channel through the top of the width for the active position, with a dampening tread covering the bottom of each base support. The longitudinal hand support optionally includes padding for added hand comfort and ring connectors on each end cap to attach to a resistance band.
US11207558B2	Low friction rehabilitation board with an integral band retaining feature and methods of rehabilitation A low friction rehabilitation board having an integral band retaining feature is described. The rehabilitation board may have a coefficient of static friction of no more than about 0.5 and in some embodiments no more than about 0.06. The rehabilitation board has a plurality of band retaining feature configured along one or both ends and may be an integral band retaining features being formed in the board. Additionally, the rehabilitation may include one or more band retaining features on one or both sides of the board. The unique configuration of the band retaining features enables rehabilitation method heretofore not possible with a single board. Resistance bands may be retained in the band retaining features and coupled to a user's limb, such as a foot or ankle, to resist motion, such as sliding or extending the foot along the low friction surface of the rehabilitation board.
US11207552B2	Fire suppression systems A fire suppression system for an aircraft (cargo) compartment comprises a source of fire suppression agent and a supply line for conducting the fire suppression agent to the compartment. The supply line comprises a pressure regulating device arranged between the source and the compartment and a pressure relief valve arranged downstream of the pressure regulating device. The pressure relief valve has an outlet which distributes the agent externally of the cargo compartment.
US11207543B2	Photobiomodulation therapy device accessories A light therapy device mounting system may include an elongate pole comprising a plurality of holes, a first end and a second end, a mounting device slideably coupled to the elongate pole via at least one hole of the plurality of holes, a top bracket slideably coupled to the first end of the elongate pole, and a bottom bracket slideably coupled to the second end of the elongate pole. The top bracket may include a top hook for receiving a top portion of a door, and the bottom bracket may include a bottom hook for receiving a bottom portion of the door.
US11207536B2	Method and apparatus for enhancing atrial fibrillation detection An example of a system may include a sensing circuit and an atrial fibrillation (AF) detection circuit. The sensing circuit may be configured to sense a cardiac signal indicative of atrial and ventricular depolarizations. The AF detection circuit may be configured to detect AF using the cardiac signal and may include a detector and a detection enhancer. The detector may be configured to detect the ventricular depolarizations using the cardiac signal, to measure ventricular intervals each between two successively detected ventricular depolarizations, and to detect the AF using the ventricular intervals. The detection enhancer may include a respiratory sinus arrhythmia (RSA) detector configured to detect RSA using the cardiac signal and may be configured to verify each detection of the AF based on whether the RSA is detected.
US11207533B2	Implantable medical device with proximal capture feature The present subject matter includes an implantable medical device with a capture feature at or near the proximal end. In some cases, the capture feature includes a hold that is configured to facilitate a releasable connection with a delivery device that is used to deliver the implantable medical device to a target implant site.
US11207530B2	Relatively compact implantable medical devices and associated methods for loading the devices into a delivery catheter An implantable medical device includes an improved tether catch formed by a relatively rigid structure that has a hook surface extending between first and second ends thereof. The second end of the structure is spaced apart from another portion of the device by a gap of a size no greater than a thickness of a tether, for which the tether catch is formed to engage, when the tether is looped within a delivery catheter. The device may be loaded into the catheter by: positioning the looped portion of the tether in close proximity to the gap of the tether catch; creating tension in the positioned tether to bring the looped portion into a perimeter of the hooked surface; and then pulling the tether so that the looped portion thereof bears against the hooked surface, thereby bringing the device into engagement with a distal-most end of the delivery catheter.
US11207528B2	Atrioventricular conduction guided His-bundle pacing Systems and methods for dynamically controlling HBP delivery based on patient AV conduction status are disclosed. An exemplary medical system includes an electrostimulation circuit to generate HBP pulses to stimulate a His bundle or a bundle branch of the heart. An AV conduction monitor circuit continuously or periodically assesses AV conduction status, and detects an indication of presence or absence of AV conduction abnormality. If an AV conduction abnormality is indicated, a control circuit may control the electrostimulation circuit to deliver the HBP pulses. Ventricular backup pacing may be delivered if HBP fails to capture and elicit ventricular activation. When the AV conduction become normal, the control circuit may withhold HBP delivery and promote patient intrinsic ventricular activation.
US11207524B2	Method and apparatus for intrachamber resynchronization Methods, apparatus, and systems are provided to control contraction of the heart. At least one sensing element receives signals indicating electrical activity of sinus rhythm of the heart. Based on the received signals, the progress of contraction of the heart is determined. Based on the progress of contraction, the chamber of the heart may then be stimulated at a plurality of locations. In another embodiment, a plurality of electrodes are implanted in the left ventricle to stimulate at multiple locations in the left ventricle for the purpose of improving hemodynamic performance and increasing cardiac output in a patient who is suffering from congestive heart failure.
US11207523B2	His-bundle pacing for rate regularization Systems and methods for pacing cardiac conductive tissue are described. An exemplary system includes an electrostimulation circuit that may generate HBP pulses to stimulate patient physiologic conduction pathway, such as a His bundle or a bundle branch. The system includes an arrhythmia detector to detect an atrial tachyarrhythmia (AT) with intermittent ventricular conduction. A control circuit may sense ventricular activation and, in response to the detected AT indication, determine or update a His-bundle pacing (HBP) configuration. The HBP may be recursively updated on a beat-by-beat basis using the sensed ventricular activation. The electrostimulation circuit may deliver HBP according to the determined or adjusted HBP configuration to regularize ventricular rate during AT.
US11207522B2	Notification indicative of a change in efficacy of therapy In some examples, a processor is configured determine whether efficacy of therapy delivered by a medical device to the patient may have changed and generate a notification based on the determination. For example, a processor may be configured to determine whether a bioelectrical brain signal indicative of activity of a brain of a patient includes a biomarker that indicates efficacy of therapy delivered by a medical device to the patient may have changed, and generate notification based on determining the bioelectrical brain signal includes the biomarker. In some examples, the processor modifies the therapy delivered to the patient prior to generating the notification.
US11207518B2	Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway Described herein are methods for treating a subject suffering from or at risk for a condition mediated by an inflammatory cytokine cascade, by electrically or mechanically stimulating vagus nerve activity in an amount sufficient to inhibit the inflammatory cytokine cascade.
US11207514B2	Male connector, medical device, and connection method A male connector is connectable to a female connector and includes: a flow path tubular member that has an opening at an end portion; a valve body that closes the opening; a housing main body; and a moving body that moves with respect to the housing main body and deforms the valve body so as to change a mode between a first mode in which the opening is closed by the valve body and a second mode in which the opening is open from the valve body. The moving body includes a locking portion that locks the female connector in a state in which the valve body and an elastic valve body of the female connector abut on each other.
US11207511B2	Methods for treating baldness and promoting hair growth The invention relates to methods of treating baldness, treating alopecia, promoting hair growth, and/or promoting hair follicle development and/or activation or stimulation on an area of the skin of a subject (for example, a human) by subjecting said area of the skin to integumental perturbation. Integumental perturbation can be used in combination with other treatments for promoting hair growth. The invention provides devices for integumental perturbation for promoting hair growth, and provides pharmaceutical compositions for use in combination with integumental perturbation for promoting hair growth.
US11207509B2	Method and device for delivery of a solution into a body orifice A diffusing applicator is provided and generally includes a head unit, and extension shaft, and a dispensing device. The head unit includes a fluid receiving space and a plurality of dispensing passageways in communication the fluid receiving space. The extension shaft is securely connected to head unit. The dispensing device holds a fluid and is connected to the extension shaft. The dispensing device is in communication with the plurality of dispensing passageways.
US11207506B2	Balloon catheter, method of manufacturing a balloon catheter, and treatment method A balloon catheter is disclosed capable of effectively delivering a drug to living body tissue and a manufacturing method of the balloon catheter, and a treatment method. The balloon catheter has a balloon at a distal portion of a catheter shaft, and is provided on a surface of the balloon with elongate bodies which are crystals of a water-insoluble drug extending in a longitudinal direction. The surface of the balloon is provided with crystal conjugates formed of a plurality of elongate bodies united to one another while being in a tilted state.
US11207503B2	Systems and methods for percutaneous intravascular access and guidewire placement A device for creating intravascular access and guidewire placement includes a main body having a lumen and a piercing member disposed in the lumen. The piercing member moves distally out of the lumen and pierces tissue while moving. A needle guide is provided for guiding the piercing member, the needle guide having a distal end which comprises a first alignment member. A guidewire has a distal tip with a second alignment member disposed on the guidewire distal tip. The first alignment member may comprise a magnetic attachment, at least one magnetic implant, a proximity sensor, an ultrasonic sensor, or other suitable system for alignment of devices disposed on opposing sides of opaque tissue. Similarly, the second alignment member may comprise a magnetic attachment or implant, a proximity sensor, or an ultrasonic sensor.
US11207500B2	System and method for underactuated control of insertion path for asymmetric tip needles A needle steering system and apparatus provides active, semi-autonomous control of needle insertion paths while still enabling a clinician ultimate control over needle insertion. A method and system controls the needle path as the needle is inserted by precisely controlling the rotation of the needle as it continuously rotates during insertion. This enables underactuated 2 degree-of-freedom (DOF) control of the direction and the curvature of the needle from a single rotary actuator. Control of the rotary motion is therefore decoupled from the needle insertion. The rotary motion controls steering effort and direction, while the insertion controls needle depth or insertion speed. In one implementation, the proposed method does not require constant velocity insertion, interleaved insertion and rotation, or known insertion position or speed. The insertion may be provided by a robot or other automated method, may be a manual insertion, or may be a teleoperated insertion.
US11207495B2	Catheter assembly with seal member A catheter assembly includes a catheter hub defining an interior cavity and a catheter tube extending distally thereof. A rigid actuator is positioned to extend proximally in the interior cavity and support a seal member positioned thereon in the interior cavity. The seal member includes a central membrane, a distal portion, and a proximal portion. An hourglass shaped actuator cavity is formed in the distal portion and receives a barbed end of the actuator. The outer surface of the seal member is in partial circumferential engagement with the catheter hub to define an air path that allows fluid communication between areas of the interior cavity distal and proximal of the seal member. The seal member may be configured for multi-use and include a biasing member that moves the seal member to force the membrane back over the actuator to close the membrane.
US11207494B2	Medical device delivery member with flexible stretch resistant distal portion A delivery member is provided for delivering and deploying an intravascular medical device. The delivery member includes a flexible distal portion including a wound wire coil surrounded by a flexible sleeve and inhibited from extending lengthwise by a stretch resistant member positioned through the lumen of the coil. The delivery member can include hypotubes positioned on either side (distally and proximally) from the wound wire coil to which the stretch resistant member and the wound wire coil can be attached.
US11207488B2	Local cooling anesthesia device, method of controlling local cooling anesthesia device, and cooling temperature regulator of local cooling anesthesia device Disclosed is a local cooling anesthesia device for spraying a coolant on a treatment site. The local cooling anesthesia device includes a housing which forms an outward form and from which the coolant is sprayed and a spraying unit installed in the housing to spray the coolant. The device also includes a cooling temperature regulator connected to the spraying unit to apply thermal energy to the sprayed coolant for temperature regulation and a control unit connected to the cooling temperature regulator to control the cooling temperature regulator. The cooling anesthesia device has functions of measuring and regulating the temperature of the coolant, and thus can apply the coolant to the treatment site within a safe temperature range according to the purpose of treatment, thereby enabling a desired treatment purpose such as local anesthesia to be safely and rapidly accomplished without side effects such as cytoclasis.
US11207487B2	System for humidification of medical gases A humidifier for delivering humidified gases to a patient includes an inlet, an outlet, a gases flow path extending from the inlet to the outlet, a permeable wall, a liquid reservoir, and a heater. The permeable wall separates the gases flow path from the liquid reservoir. The heater heats liquid stored in the liquid reservoir to form vapour, and the vapour passes through the permeable wall to the gases flow path to humidify gases in the gases flow path. Another inline humidifier for delivering humidified gases to a patient includes an inlet and an outlet and holds a tape made of hydrophilic or hygroscopic material. The tape is pre-soaked with water and can include a heating element. The heating element heats the tape and the stored water to release the stored water as vapour and thereby humidify gases passing through the inline humidifier.
US11207485B2	Humidification arrangement for a respiratory apparatus An air delivery tube for a CPAP system includes a first end configured to connect to a flow generator of the CPAP system and a second end configured to connect to a patient interface of the CPAP system. The air delivery tube also includes a central lumen that is formed by an inner wall of the air delivery tube and is configured to convey pressurized breathable gas from the first end to the second end. In addition, a circumferential chamber surrounds the central lumen and is configured to retain a supply of water. A wick is located within the central lumen and is connected to the inner wall.
US11207483B2	Tracheostomy tube with filleted flange Various embodiments of a tracheostomy tube having neck flanges with filleted ends are provided. In certain embodiments, the neck flange may include a fillet extending from a bottom surface of the neck flange to a tip of the neck flange. In addition, the filleted end may also be tapered from a top surface of the neck flange to the tip of the neck flange. The neck flange may also include several curved edges, such as curved edges from the tip of the neck flange to side surfaces of the neck flange, and a curved bottom surface from side surface to side surface of the neck flange.
US11207482B2	Device and method for the dynamically sealing occlusion or space-filling tamponade of a hollow organ A device (1) for the tracheal intubation of and the administration of ventilation to a patient for rapid volume-compensating sealing of the trachea, wherein the sealing surfaces of a preferably fully and residually formed balloon-like film body (4) abut the wall of the trachea with a sealing pressure of the balloon (4) which is as constant as possible and follow the thoracic pressure acting on the balloon with the least possible time latency with regard to corresponding fluctuations of the balloon inflation pressure, and the trachea is kept sealed under such dynamic fluctuations or respiration synchronously alternating fluctuations of the balloon inflation pressure. This is enabled by a defined large lumen (7, 5) supply of the balloon inflation medium, the supplying lumen being measured in such a way that a sealing pressure-maintaining extracorporeal volume compensation that works in a time synchronous manner can be achieved in the sealing balloon element.
US11207478B2	Aerosol production assembly including surface with micro-pattern The present disclosure relates to an aerosol production assembly. The aerosol production assembly may include a reservoir that contains an aerosol precursor composition and an atomizer that receives the aerosol precursor composition from the reservoir and heats the aerosol precursor composition to produce an aerosol. The aerosol production assembly may additionally include a body that directs the aerosol through an outlet. The body may include a surface including a micro-pattern that defines at least one of hydrophobic and anti-microbial properties. The surface including the micro-pattern may not include a chemical coating that provides these properties. Rather, the surface may define a three-dimensional structure that provides hydrophobic and/or anti-microbial properties. A related assembly method is also provided.
US11207476B2	Flexible bag spacer device for an inhaler The invention relates to a valveless spacer device for a metered dose inhaler (MDI), the spacer device comprising a body having an inlet and an outlet opposed from the inlet, a demountable, flexible bag attached to the body, the bag and body together defining a chamber, such that the inlet and outlet are in fluid flow communication with an interior of the chamber, wherein the inlet is configured to be connected to an MDI containing a drug to be inhaled and wherein the flexible bag, following actuation of the MDI, serves as a reservoir allowing for the formation of a cloud or mist of the drug therewithin which is then ready for inhalation, the flexible bag being configured to be at least partially deflatable and at least partially inflatable commensurate with a single breath and/or rebreathing.
US11207475B2	Method and system for delivery of an aerosolized medicament The method and system according to preferred embodiments of the present invention allows an effective delivery of aerosolized medicament (e.g., a surfactant) to the patient's lungs. According to a preferred embodiment, the method of the present invention provides an efficient delivery of the aerosol medicament (possibly breath synchronized). A glass vial in which medicaments are usually stored and shipped is used directly as a component of the system. Its function in the system is that of an intermittently pressurized chamber that can inject the surfactant into the catheter of the atomizer device. According to a preferred embodiment the delivery can be done in phase with the beginning of each inspiration. The main elements of the system are: a source of compressed gas, the already mentioned medicament vial, a catheter, and optionally means to detect the breathing pattern and a control unit.
US11207468B2	Syringe A syringe is provided, including a syringe barrel, a needle set and a push rod. A front end part is provided in the syringe barrel. An end of the needle set has an open area, the open area is transversely provided with a first snap part. The push rod is slidably disposed within the syringe barrel, and an end of the push rod facing the front end part has a second snap part. When the push rod is slidingly moved to the front end part, the second snap part is engaged with the first snap part.
US11207465B2	Cartridge insertion for drug delivery device A method and assembly are disclosed for interfacing between a drug cartridge and a drug delivery device. Optionally, the drug delivery device includes a compartment that retains the cartridge during drug delivery and/or a stopper pushing assembly mounted to the device behind (proximal to) the compartment. In some embodiments, the cartridge may be inserted laterally into the compartment in front of the pushing assembly. For example, the delivery device may include a moving cartridge bay. The cartridge is optionally inserted into the bay and/or the bay and cartridge optionally move into the cartridge compartment. Alternatively or additionally, the cartridge compartment may have a proximal opening into which the cartridge is inserted and/or the pushing assembly may be moved into position after insertion of the cartridge. In some embodiments the cartridge may have a distal seal that is broken by a longitudinal movement.
US11207463B2	Apparatuses, systems, and methods for identifying an infusate in a reservoir of an infusion device Apparatuses and methods for identifying an infusate in a reservoir of an infusion device and systems for use in filling fluid delivery devices are provided. An exemplary apparatus for identifying an infusate in a reservoir of an infusion device includes a chamber in selective fluid communication with the reservoir. Further, the apparatus includes an indicator located in the chamber. The indicator exhibits a visual change when contacted by an infusate. The apparatus also includes a detector arrangement to identify the infusate by detecting the visual change in the indicator. An exemplary detector arrangement may include a camera to capture an image of the infusate and indicator in the chamber, and an identifier element to compare image data to a library of stored image data.
US11207460B2	Drug delivery storage device and system A drug delivery system includes a storage container defining one or more storage compartments and having at least one container sensor coupled thereto, a container condition change mechanism coupled to the storage container for imparting a change on one or more conditions of the one or more storage compartments, at least one drug delivery device adapted to deliver a drug to a user and adapted to be at least partially disposed within one or more of the one or more storage compartments, at least one delivery device sensor, a delivery device condition change mechanism coupled to the drug delivery device, and a controller coupled to the storage container. The storage container may be adapted to hold a number of drug delivery devices within a number of sealable storage compartments. The container sensor is adapted to sense a condition of the storage container, and the delivery device sensor is adapted to sense a condition of the at least one drug delivery device. The controller is adapted to instruct the container condition change mechanism and/or the delivery device change mechanism to impart a change on at least one condition of the storage container and/or the drug delivery device.
US11207456B2	Method and device for infusion of pharmacologic agents and thrombus aspiration in artery A catheter device and method for treating an artery with thrombus, the catheter comprising an inflatable member. A carrier catheter has a proximal end and a distal end adapted to be inserted percutaneously into an artery, the carrier catheter having a tubular body adjacent to a rear end of the inflatable member. An inflating tube passes through the tubular body and having an open front end in fluid communication with the inflatable member to inflate same. An infusion tube is adapted to infuse pharmacologic agents, the infusion tube passing through the tubular body and having an open front end extending beyond the inflatable member. An aspiration tube is adapted to aspire the thrombus, the aspiration tube passing through the tubular body and having an open front end between the carrier catheter and the inflatable member.
US11207455B2	Membrane device for blood separation and methods of making and using the same Disclosed herein are membrane device embodiments that can be used for separating blood plasma and/or blood serum from blood samples. The membrane device embodiments comprise built-in features that facilitate blood plasma and/or blood serum separation and also provide the ability to detect, quantify, and qualify analytes present in a blood sample. The membrane device embodiments are portable and just a single membrane can be used for a plethora of detection and analysis techniques. Also disclosed herein are embodiments of methods for making and using the membrane device.
US11207449B2	Methods and materials for treating blood vessels This document provides methods and materials for treating a mammal (e.g., a human) having one or more stenotic blood vessels. For example, amnion coated balloons that can be used in balloon angioplasty are provided.
US11207446B2	Decellularized placental membrane and methods of preparing and use thereof A method of preparing a decellularized placental membrane is provided. The method comprises removing cells from a pre-decellularized placental membrane comprising an amnion layer and a chorion layer to produce a decellularized placental membrane without separating the amnion layer from the chorion layer. The pre-decellularized placental membrane is obtained from an amniotic sac, and the decellularized placental membrane comprises the amnion layer and the chorion layer. Also provided is a decellularized placental membrane and a placenta-derived graft comprising the decellularized placental membrane. Further provided are the uses of the decellularized placental membrane or the placenta-derived graft.
US11207445B2	Allograft bone putty and methods of making the same A method of preparing a reconstitutable implantable bone putty includes combining a bone matrix derived from human bone and gelatin particulates derived from human tissue at a concentration of the bone matrix by dry weight of 20 to 60 percent to form the reconstitutable implantable bone putty. Preparing the gelatin particulates includes supplying a gelatin precursor of bone or soft tissue from a human, treating the gelatin precursor with phosphoric acid to generate a gelatin-acid mixture, neutralizing the gelatin-acid mixture with an alkali to a pH between 6 and 8 to allow a gelatin-rich solution and a waste solution to separate, removing residual salts from the gelatin-rich solution to obtain purified gelatin, drying the purified gelatin, and reducing the purified gelatin to particulates having a largest dimension less than 300 μm. A method of preparing an implantable bone putty includes adding a reconstitution media to the reconstitutable implantable bone putty.
US11207440B2	Volatile composition dispenser with increased membrane exposure and volatile composition weight loss A volatile composition dispenser includes a housing having opposing first and second walls that are joined along their peripheries to one another. The first wall has an aperture and the second wall has a plurality of apertures. Within the housing, rests a volatile composition cartridge and a gap, which exists between the cartridge and a bottom surface of the housing, wherein said bottom surface is formed from a joinder of a base portion of one or both of the first and second walls, and wherein, upon activation, the exposure percentage of the dispenser is from about 40% to about 90%; wherein at least about 60% of the total surface area of the plurality of apertures results from individual apertures of said plurality that each have an area of at least 30 mm2 and an aspect ratio of at least about 1:2. Dispenser of a similar housing, cartridge, and gap when is activated by a user and thirty days after said activation, exhibits about 70% to 90% weight loss of said volatile composition of a partially exposed membrane of a fully exposed membrane.
US11207438B2	Low wattage powered wax warmers A wax warmer assembly includes a housing having an outermost edge defining an opening and an annular ridge below the outermost edge. The wax warmer assembly further includes a dish with a peripheral edge, a heater affixed to the dish, and a power cord in electrical communication with the heater. The heater is operable to only draw 10 Watts of power or less from a power source. Further, the dish is disposed in the opening of the housing and the peripheral edge of the dish engages with the annular ridge of the housing.
US11207433B2	Imaging agents and uses thereof The present invention relates to various compositions and methods of using these compositions for imaging natriuretic peptide receptors using, for example, positron emission tomography.
US11207426B2	Compositions and methods for selective inhibition of grainyhead-like protein expression In some aspects, the disclosure relates to methods and compositions for modulation of miR-122 expression in a cell or a subject. In some embodiments, methods and compositions described by the disclosure are useful for the treatment of liver-associated diseases (e.g., chronic liver disease, alcoholic liver disease).
US11207425B2	Guide RNA molecule and method for treating cancer A gRNA molecule includes a first domain complementary to at least a portion of TCOF1 gene, and a second domain for binding with Cas9 protein, and a kit includes the gRNA molecule. A method of treating a subject suffering from a cancer associated with an elevated expression of TCOF1 gene includes the step of administering an effective amount of a first recombinant vector comprising the gRNA molecule of the invention to the subject. A method of inhibiting the expression of TCOF1 gene in cancer cells associated with an elevated expression of TCOF1 gene includes contacting the cancer cells with a first recombinant vector, wherein the first recombinant vector comprises a gRNA molecule comprising a first domain complementary to at least a portion of TCOF1 gene and a second domain binding with Cas9 protein.
US11207423B2	Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs Disclosed are biodegradable nanocarriers that have a net positive surface charge and zeta potential between about +2 to about +20 mV. The positive surface charge of the nanocarriers is provided by peptides that are covalently attached to the surface of the nanocarriers. The nanocarriers may comprise a drug and may be administered for localized and sustained delivery of the drug.
US11207422B2	MOMP telonanoparticles, and related compositions, methods and systems A telodendrimer-nanolipoprotein particle (t-NLP), comprising one or more membrane forming lipids, one or more telodendrimers, and a scaffold protein and a Chlamydia major outer membrane protein (MOMP) comprising a MOMP hydrophobic region, and related compositions methods and systems.
US11207419B2	Cadherin-17 specific antibodies and cytotoxic cells for cancer treatment Embodiments of the present disclosure relate to cadherin-17 specific antibodies and cytotoxic cells for cancer treatment. For example, an antibody may have specificity for cadherin-17 and include an amino acid sequence having at least 70% similarity with an amino acid sequence selected from SEQ ID NO: 1-21.
US11207417B2	Drug-polymer conjugate A polymer-prostaglandin conjugate comprising: a polymer backbone comprising a plurality of moieties of formula (I): where: T represents a triazole moiety; Q is independently selected at each occurrence and may be present or absent and when present represents a linking group; R is selected from the group consisting of linear or branched hydrocarbon; D is selected from prostaglandins; and L is a group of formula (II) wherein R5 is selected from hydrogen and C1 to C6 alkyl; (R) indicates the end of the group bonded to the R group; and (D) indicates the end of the group attached to the group D.
US11207415B2	Peptide drug improvement using vitamin B12 and haptocorrin binding substrate conjugates The invention involves the coupling of compounds that can be bound by Haptocorrin (R-binder; Transcobalamin I; HC) to a target drug to improve pharmacokinetics, avoid undesirable side effects, and/or modify CNS access and localization. The pharmaceutical effect may be improved by conjugating the drug to haptocorrin binding substrate. This allows the conjugate to become bound to unsaturated haptocorrin in the blood, thereby protecting the drug from metabolism or excretion to increase protein half-life while not interfering with the efficacy of the protein drug. The conjugation may additionally prevent the drug from reaching the central nervous system or modify where the drug localizes and produces undesirable side effects such as nausea or hypophagia. Such a route also would prevent, in all case save for actual vitamin B12, binding by serum transcobalamin II (TCII), and thus not cause B12 deficiency with long term use.
US11207414B2	Cannabinoid glycoside prodrugs and methods of synthesis The present invention relates to cannabinoid glycoside prodrugs suitable for site- and tissue-specific delivery of cannabinoid molecules. The present invention also relates to methods of forming the cannabinoid glycoside prodrugs through glycosyltransferase mediated glycosylation of cannabinoid molecules.
US11207413B2	Succulent extract and alginate combined solutions and products incorporating them The invention provides a composition including a succulent extract and an alginic acid component consisting of alginic acid and/or one or more salts thereof, wherein the succulent extract is present in an amount in a range from 0.1 wt % to 1000 wt % relative to the alginic acid component, both on a dry basis.
US11207409B2	X-RAY psoralen activated cancer therapy (X-PACT) with associated treatments A system (and associated method) for treating a human or animal body. The system has a photoactivatable drug for treating a first diseased site, a first pharmaceutically acceptable carrier including one or more phosphorescent or fluorescent agents which are capable of emitting an activation energy into the body which activates the photoactivatable drug, a first device which infuses the first diseased site with a photoactivatable drug and the first pharmaceutically acceptable carrier, a first energy source which irradiates the diseased site with an initiation energy to thereby initiate emission of the activation energy into the body, and a supplemental treatment device which administers one or both of a therapeutic drug or radiation to the body at a second diseased site or the first diseased site, to provide an immune system stimulation in the body.
US11207408B2	Biophotonic compositions, methods, and kits for inhibiting and disrupting biofilms The present document describes methods of using compositions for inhibiting biofilm formation, or disrupting existing or developing biofilms in a subject, which composition comprises at least one chromophore and a pharmacologically acceptable carrier.
US11207406B2	Anti-LAG3 antibodies and antigen-binding fragments The present invention includes antibodies and antigen-binding fragments thereof that specifically bind to human or cynomolgous monkey LAG3 as well as immunoglobulin chains thereof and polynucleotides encoding the same along with injection devices comprising such antibodies or fragments. Vaccines including such antibodies and fragments as well as compositions comprising the antibodies and fragments (e.g., including anti-PD1 antibodies) are included in the invention. Methods for treating or preventing cancer or infection using such compositions are also provided. In addition, methods for recombinant expression of the antibodies and fragments are part of the present invention.
US11207404B2	Compositions and uses The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
US11207403B2	Human cytomegalovirus immunogenic composition The invention relates to an immunogenic composition comprising an HCMV gH/gL/UL128/UL130/UL131 pentameric complex antigen and a TH1-inducing adjuvant. It further relates to the immunogenic composition for use as an HCMV vaccine.
US11207399B2	Influenza virus mutants and uses therefor Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
US11207393B2	Regulatory T cell PD-1 modulation for regulating T cell effector immune responses The present invention is based, in part, on the identification of methods of modulating PD-1 expression and/or activity in regulatory T cells (Tregs) to thereby regulate effector immune responses in effector T cells (Teffs).
US11207391B2	Anti-ICOS agonist antibodies and uses thereof The present invention provides isolated monoclonal antibodies (e.g., humanized and human monoclonal antibodies) that bind to human Inducible T Cell COStimulator (ICOS) and exhibit therapeutically desirable functional properties, e.g., the ability to stimulate human ICOS activity. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells, and methods for expressing the antibodies of the invention are also provided. Immunoconjugates, bispecific molecules, and pharmaceutical compositions comprising the antibodies of the invention are also provided. The antibodies of the invention can be used, for example, as an agonist to stimulate or enhance an immune response in a subject, e.g., antigen-specific T cell responses against a tumor or viral antigen. The antibodies of the invention can also be used in combination with other antibodies (e.g., PD-1, PD-L1, and/or CTLA-4 antibodies) to treat, for example, cancer. Accordingly, the antibodies can be used in therapeutic applications and methods to detect ICOS protein.
US11207389B2	Composition for treatment or prevention of infectious inflammatory diseases, or composition for immune enhancement, comprising tryptophanyl-tRNA synthetase as an active ingredient The present invention relates to a composition for treatment or prevention of infectious inflammatory diseases comprising tryptophanyl-tRNA synthetase as an active ingredient, and a composition for immune enhancement. More specifically, the present invention relates to a pharmaceutical composition for treatment or prevention of infectious inflammatory diseasess comprising tryptophanyl-tRNA synthetase as an active ingredient, a food composition for preventing or improving, a veterinary composition for preventing or treating, and a composition for immune enhancement comprising a tryptophanyl-tRNA synthetase as an active ingredient, respectively.The composition of the present invention can be effectively used for preventing or treating diseases of humans and animals caused by infection from bacteria, viruses or fungi and the like by inhibiting infections such as bacterial, viral, and fungal infections at an early stage particularly through activating innate immune response.
US11207385B2	Melanocortins and methods of use thereof In some aspects, the present disclosure provides compositions and methods for treating disease, e.g., inflammatory disease. Compositions herein comprise one or more polypeptide fragments of proopiomelanocortin or variants thereof. The one of more polypeptide fragments of proopiomelanocortin or variants thereof may be linked by a linker, e.g., a peptide linker, to form a fusion polypeptide.
US11207380B2	Molecular signature of cancer The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme.
US11207374B2	Lantibiotics, lantibiotic-producing bacteria, compositions and methods of production and use thereof The present disclosure relates to novel lantibiotics, lantibiotic pharmaceutical compositions, isolated and recombinant lantibiotic-producing bacteria, bacterial pharmaceutical compositions, methods of producing novel lantibiotics from lantibiotic-producing bacteria, and methods of using such lantibiotics, lantibiotic pharmaceutical compositions, and bacterial pharmaceutical compositions to treat gram-positive bacteria infections, including vancomycin resistant enterococci infections, in patients, and to treat food and other objects to avoid gram-positive bacteria contamination.
US11207373B2	Agitation process for preparing a carbetocin drug product The present disclosure includes a method of making an improved carbetocin drug product. The disclosed method for making an improved carbetocin drug product comprises agitating a carbetocin preparation containing an aqueous solution of carbetocin and one or more excipients for a period of time to initiate the formation of aggregate-forming solids and filtering off the aggregates that form before further processing the remaining carbetocin into a final drug product. The present disclosure also relates to an improved carbetocin drug product, wherein the drug product is substantially free of aggregate-forming solids. The disclosed carbetocin drug product can be used for the treatment of a neurodevelopmental disorder, such as Präder-Willi syndrome. Additionally, the disclosed carbetocin drug product shows content uniformity of carbetocin over long periods of time before and after one or more freeze/thaw cycles, provides enhanced convenience and patient compliance, and/or are highly concentrated.
US11207366B2	Traditional Chinese medicine composition comprising dried tangerine peels and dark tea for treating diabetes and preparation method thereof A traditional Chinese medicine composition for treating diabetes and a preparation method thereof, the composition comprises dried tangerine peels and dark tea. The preparation method utilizes Pu'er tea to shuffle placement with the dried tangerine peels to preserve the dried tangerine peels, mixes different kinds of dried tangerine peels of different aging years, adds the mixed dried tangerine peels with pile-fermented black tea, presses the mixed black tea into tea bricks, and secondarily-ferments the tea bricks, then ages the secondary fermented tea bricks for two years.
US11207363B2	Pharmaceutical composition for prevention or treatment of Alzheimer's disease, comprising mountain-cultivated ginseng extract The present invention provides a pharmaceutical composition for preventing or treating Alzheimer's disease and a food composition for relieving symptoms of Alzheimer's disease, which comprise a mountain-cultivated ginseng extract. The composition comprising the mountain-cultivated ginseng extract of the present invention is beneficially used as a pharmaceutical composition for preventing or treating Alzheimer's disease in the medical field for the treatment of Alzheimer's disease or as a food composition for relieving the symptoms of Alzheimer's disease.
US11207353B2	Immunocompatible amniotic membrane products Provided herein is a placental product comprising an immunocompatible amniotic membrane. Such placental products can be cryopreserved and contain viable therapeutic cells after thawing. The placental product of the present invention is useful in treating a patient with a tissue injury (e.g. wound or burn) by applying the placental product to the injury. Similar application is useful with ligament and tendon repair and for engraftment procedures such as bone engraftment.
US11207351B2	Materials and methods for engineering cells and uses thereof in immuno-oncology Materials and methods for producing genome-edited cells engineered to express a chimeric antigen receptor (CAR) construct on the cell surface, and materials and methods for genome editing to modulate the expression, function, or activity of one or more immuno-oncology related genes in a cell, and materials and methods for treating a patient using the genome-edited engineered cells.
US11207349B2	Combined chimeric antigen receptor targeting CD19 and CD20 and application thereof The present invention provides a combined chimeric antigen receptor targeting CD19 and CD20 and application thereof. Specifically, the present invention provides a combined chimeric antigen receptor targeting CD19 and CD20, which comprises a scFv targeting CD19 and CD20, a hinge region, a transmembrane region, and an intracellular signaling domain. The present invention provides a nucleic acid molecule encoding the chimeric antigen receptor and a corresponding expression vector, a CAR-T cell, and applications thereof. The experimental results show that the chimeric antigen receptor provided by the present invention shows extremely high killing ability against tumor cells. The chimeric antigen receptor of the present invention targets CD19 and/or CD20 positive cells and can be used to treat CD19 and/or CD20 positive B-cell lymphoma, leukemia and other diseases.
US11207344B2	Solubilization enhancer for pyrroloquinoline quinone, composition comprising same and method for enhancing solubilization Provided is a solubilization enhancer for pyrroloquinoline quinone or a salt thereof in an aqueous solvent, comprising resistant dextrin as an active ingredient.
US11207342B2	High density lipoprotein binding protein (Hdlbp/Vigilin) iRNA compositions and methods of use thereof The invention relates to double stranded ribonucleic acid (dsRNA) agents and compositions targeting a High Density Lipoprotein Binding Protein (Hdlbp/Vigilin) gene, as well as methods of inhibiting expression of Hdlbp/Vigilin and methods of treating subjects having a disorder of lipid metabolism, such as mixed hyperlipidemia, hypertriglyceridemia or hypercholesterolemia, using such dsRNA agents and compositions.
US11207335B2	Methods of using human milk oligosaccharides for improving airway respiratory health Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to preterm infants, term infants, toddlers, and children for improving airway defense mechanisms.
US11207331B2	Agents, compositions and methods for enhancing neurological function Neuro-enhancing agents, compositions and methods are disclosed herein. Preferred neuro-enhancing agents of the present invention include progesterone and metabolites of progesterone, such as 3α-hydroxy-5α-pregnan-20-one (THP). These agents yield neuro-enhancing effects on neural cells that include neural progenitor and/or stem cells, whereby the agents stimulate mitosis of neural progenitor cells, stimulate neurite growth and organization, protect against neural loss, or one or more of these neural processes. Thus, the neuro-enhancing agents, compositions and methods disclosed herein are useful to reverse or prevent neurological disease or defects associated with neural loss or degeneration, such as Alzheimer's disease, neurological injuries, including injuries resulting from radiation therapy, and age-related neurological decline, including impairments in memory and learning.
US11207330B2	Mirtazapine for use in medication overuse headache based on tension-type headache Mirtazapine is useful for the treatment and/or prophylaxis of medication overuse headache based on tension-type headache. Moreover, a pharmaceutical composition and/or the use of mirtazapine for the manufacture of a medicament, are useful against medication overuse headache based on tension-type headache, and the treatment of medication overuse headache based on tension-type headache.
US11207324B2	Treatment of HER2 positive cancers In one aspect, the present invention provides a method for treating or ameliorating the effects of a HER2 positive cancer in a subject. In some embodiments, the method comprises administering a combination therapy comprising an anti-HER2 antibody and tucatinib. In some embodiments, the method further comprises administering a chemotherapeutic agent (e.g., an antimetabolite) to the subject. Pharmaceutical compositions and kits are also provided herein.
US11207322B2	Method and composition related to combination therapy for addiction Certain embodiments are directed to methods of treating or preventing an addictive behavior in a subject by administering to the subject an effective amount of a 5-HT2C receptor agonist in combination with a DA D3/D4 receptor antagonist.
US11207320B2	Compositions and methods for cancer expressing PDE3A or SLFN12 The present invention features improved methods of identifying patients having cancer (e.g., melanoma, adenocarcinoma, lung, cervical, liver or breast cancer) using biomarkers (e.g., PDE3A, SLFN12) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., DNMDP, zardaverine, and anagrelide).
US11207316B2	Ketamine or dextromethorphan formulations and methods of use The present invention provides a method of treating depression disease in a patient comprising administering to a mucosal membrane of a patient an effective amount of a pharmaceutically acceptable composition comprising an effective amount of ketamine or dextromethorphan, or both ketamine and dextromethorphan, wherein the mucosal administration of the ketamine or dextromethorphan containing composition allows for the mucosal absorption of the composition eliminating the digestive tract of the patient for effecting a rapid acting antidepressant treatment of the patient. Preferably, this method includes administering the composition to the oral cavity, and more preferably to the buccal cavity, of the patient. A pharmaceutically acceptable composition comprising ketamine or dextromethorphan and a vehicle is disclosed. A biomarker for identifying a depressive disease is set forth. A method of treating depressive illness in a patient using dextromethorphan via the oral route is provided.
US11207308B2	Pharmaceutical compositions for combination therapy This invention relates to novel pharmaceutical compositions comprising a therapeutically effective combination of a dopaminergic stabilizer known as Pridopidine, and an inhibitor of the vesicular monoamine transporter type 2 (VMAT) known as Tetrabenazine. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for improving the symptomatic therapeutic effects, and for reducing the adverse effects, of Tetrabenazine in the treatment of movement disorders, and in articular movement disorders associated with Huntington's disease, Gilles de la Tourette's syndrome, or tardive dyskinesia.
US11207305B2	Antibiotic combination therapies The invention provides antibiotic combination therapies for treating an A. baumannii infection in a subject. The combination therapies include rifabutin and a second antibiotic, such as colistin and cefiderocol.
US11207303B2	Therapeutic agent for fibrodysplasia ossificans progressiva The present invention relates to a prophylactic or therapeutic agent for fibrodysplasia ossificans progressiva comprising as an active ingredient, at least one compound selected from the group consisting of rapamycin, temsirolimus, everolimus, ridaforolimus, TAFA93, umirolimus, olcorolimus, zotarolimus, and pharmaceutically acceptable salts thereof.
US11207302B2	1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase The present invention is directed to 1, 2, 5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2, 3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1, 2, 5-oxadiazole derivatives.
US11207301B2	Sphingosine 1 phosphate receptor agonists for neuroprotection Methods of treating conditions for which S1P-mediated neuroprotection is medically indicated, comprising administering to a subject in need thereof an agonist of the sphingosine 1-phosphate receptor (S1P receptor); such as a compound having the following structure (See Formula 1): or a pharmaceutically acceptable salt, stereoisomer, homolog, hydrate or solvate thereof.
US11207300B2	Method of treatment of Shwachman-diamond syndrome The invention relates to compounds for the treatment of ribosomopathies. In particular, it refers to compounds for the treatment of Shwachman-Diamond Syndrome (SDS) and other ribosomopathies, such as Diamond-Blackfan Anemia (DBA), X-linked dyskeratosiscongenita (DKC) and Treacher Collins syndrome (TCS).
US11207297B2	Liquid pharmaceutical composition of clonidine The present invention relates to liquid pharmaceutical composition suitable for oral administration comprising clonidine or pharmaceutically acceptable salts thereof with at least one buffer and at least one preservative. The present invention also relates to process for preparing the said liquid pharmaceutical composition.
US11207294B2	Methods of treating generalized pustular psoriasis with an antagonist of CCR6 or CXCR2 The present disclosure provides, inter alia, methods of treating generalized pustular psoriasis (GPP) by administering an effective amount of a Chemokine Receptor 6 (CCR6) antagonist and/or a C—X—C motif chemokine receptor 2 (CXCR2) antagonist. Also provided herein are methods of modulating dysregulated IL-36 signaling in a subject in need thereof and methods of reducing neutrophil, inflammatory dendritic cell (iDC), and/or CD4 T cell accumulation in a subject in need thereof, said methods, include administering an effective amount of a Chemokine Receptor 6 (CCR6) antagonist and/or a C—X—C motif chemokine receptor 2 (CXCR2) antagonist. In some embodiments, the CCR6 and/or CXCR2 antagonist has the formula:
US11207293B2	Therapeutic compositions and uses thereof The present invention discloses a composition and method of use for the general improvement of hypertension, high cholesterol, and cardiovascular health. The novel composition is comprised of thiamin (vitamin B1), vitamin B2 (as riboflavin-5′-phosphate), niacin (vitamin B3, as niacinamide), vitamin B6 (as pyridoxine hydrochloride), folic acid, vitamin C, vitamin D, calcium (as calcium carbonate), magnesium (as magnesium taurate), aged garlic extract, olive leaf extract (as 20% oleuropein), coenzyme Q10 (as ubiquinol), L-Arginine (as hydrochloride), L-Citrulline (as malate), and lycopene.
US11207291B2	Antimicrobial compositions comprising cannabinoids and methods of using the same The invention relates is directed to antimicrobial compositions comprising cannabinoid compounds and methods of utilizing the antimicrobial compositions to inhibit the growth of microorganisms, to treat and/or prevent microbial infections.
US11207287B2	Combination comprising N-acetyl-L-cysteine and its use A combination of N-acetyl-L-cysteine, selenium in the form of selenomethionine and melatonin, and a medical product or pharmaceutical composition comprising such combination, useful for the treatment of a variety of diseases and conditions is described. The combination of N-acetyl-L-cysteine, selenium in the form of selenomethionine and melatonin is also useful for cosmetic treatment of skin and as an antibacterial agent.
US11207281B2	Bupropion as a modulator of drug activity Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.
US11207275B2	Treatment of addiction and impulse-control disorders using PDE7 inhibitors This disclosure is directed to treatment of addictions and primary impulse-control disorders using phosphodiesterase 7 (PDE7) inhibitors, alone or in combination with other therapeutic agents.
US11207270B2	Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances Controlled release dosage forms are described herein. The controlled release formulations described herein provide prolonged delivery of high dose drugs that are highly water soluble and highly hygroscopic. In specific embodiments, controlled release dosage forms for delivery of a drug selected from GHB and pharmaceutically acceptable salts, hydrates, tautomers, solvates and complexes of GHB. The controlled release dosage forms described herein may incorporate both controlled release and immediate release formulations in a single unit dosage form.
US11207264B2	Cosmetics composition having improved water absorbability and oil absorbability A cosmetics composition having improved water absorbability and oil absorbability is provided. The cosmetics composition effectively controls sweat and sebum, thereby making it possible to improve persistence of make-up and to keep skin from looking dull.
US11207263B2	Cosmetic compositions This invention relates to a cosmetic composition comprising: (A) a film forming composition that can produce a tack free surface comprising: (I) a hydrosilylation reaction product of: (a) a silicone resin having the formula: (R1R22SiO1/2)w(R1R2SiO2/2)x(R2SiO3/2)y(SiO4/2)z wherein R2 is a C1 to C10 hydrocarbon group free of aliphatic unsaturation, R1 is R2 or an alkenyl group, w is from 0.3 to 0.6, x is from 0.0 to 0.2, y is 0, z is from 0.4 to 0.7, w+x+y+z=1.0, and w+z is from 0.85 to 1.0, with the proviso that the silicone resin (a) has at least two silicon-bonded alkenyl groups per number average molecule; (b) a polyether compound having the formula: R3O(C2H4O)c(C3H6O)dR3 wherein R3 is a monovalent unsaturated aliphatic hydrocarbon group containing 2 to 12 carbon atoms, c is from 0 to 50, d is from 0 to 50, and the value of c+d is greater than zero; (c) an SiH functional organopolysiloxane having the general formula: HcR3-cSiO(R2SiO)a(RHSiO)bSiR3-cHc wherein c is 0 or 1, R can be identical or different and is a monovalent, optionally substituted hydrocarbon group with 1 to 18 carbon atoms per molecule, a and b are integers, with the proviso that the sum of a+b is 0 to 300, and wherein the organopolysiloxane contains SiH in amounts from 0.01 to 0.4 wt %; (d) a hydrosilylation catalyst; and (e) carrier solvent; and (II) a silicone resin having the formula: (R43SiO1/2)u(SiO4/2)v wherein R4 is a C1 to C10 to do hydrocarbon group free of aliphatic unsaturation, u is from 0.3 to 0.6, v is from 0.4 to 0.7, and the value of u+v is 1.0; and (B) at least one cosmetic ingredient.
US11207262B2	Styling composition for curly hair The present application discloses a hairstyling composition, particularly for curly hair, which produces tight, long-lasting curls without requiring the use of high heat applied to the hair. The composition comprises a sulfonate-based copolymer (such as sodium polystyrene sulfonate), an aqueous polyurethane dispersion (such as polyurethane-34) and a cosmetically-acceptable carrier (such as water). The method of styling hair using the defined composition, without requiring the application of high heat to the hair, is also disclosed.
US11207261B2	Personal care compositions with two benefit phases Methods of enhancing deposition of a high viscosity benefit agent can include manufacturing a personal care composition comprising the high viscosity benefit agent and a low viscosity benefit agent by adding the high viscosity benefit agent and the low viscosity benefit agent separately to a cleansing phase.
US11207260B2	Phosphonic ethylenic polymer and cosmetic uses thereof The invention relates to a cosmetic process for caring for or making up keratin materials, comprising the topical application to the keratin materials of a cosmetic composition comprising a phosphonic polymer derived from the polymerization of: (a) 45% to 95% by weight of ethylenic monomer bearing an at least C8 linear or branched alkyl group; (b) 5% to 25% by weight of vinylphosphonic acid monomer; (c) 0 to 50% by weight of additional monomer chosen from linear or branched C1C6 alkyl (meth)acrylates, C6-C12 cycloalkyl (meth)acrylates, and polydimethylsiloxanes bearing a mono(meth)acryloyloxy end group, optionally combined with an additional compound chosen from polyamine compounds bearing several primary amine and/or secondary amine groups, aminosilanes, salts of divalent or trivalent metal ions, clays and metal oxides. The process makes it possible to obtain a film-forming deposit that has good resistance to water, to oil and to sebum. The film is also non-tacky and transfer-resistant. The invention also relates to polymers containing the three monomers (a), (b) and (c).
US11207258B2	Capsule containing functional substance and method for manufacturing said capsule It is an object of the present invention to provide a capsule comprising a functional substance and having good shape stability and a good feeling of use. A method for producing a capsule, comprising steps of mixing gelatin and a functional substance; adding a carbodiimide crosslinking agent to crosslink the gelatin with the carbodiimide crosslinking agent; solidifying the crosslinked gelatin; and grinding the solidified gelatin.
US11207252B2	Synergistic preservative blends A synergistic preservative composition comprises sorbic acid or a salt thereof, benzyl alcohol, and a mixture of (i) 1,2-propanediol and/or 1,3-propanediol, and (ii), 4-butanediol and/or 1,3-butanediol. The composition is particularly suited for the preservation of cosmetics and personal care products.
US11207251B2	Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and chlorphenesin, and cosmetic composition containing same The invention relates to an antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and chlorphenesin, and also to a cosmetic composition containing such a mixture. Use in caring for, making up and cleansing keratin materials.
US11207250B2	Elastomeric articles having skin care properties and methods for their production The present application provides elastomeric articles that are able to deliver skin care properties to a person wearing or coming into contact with the article. The articles comprise an elastomeric film a plant stem cell material. The plant stem cell material may be in the form of a bilayer membrane-encapsulated plant stem cell material. The plant stem cell material may be present as a layer or coating on a surface of the elastomeric film. Also provided are methods for the production of the articles.
US11207249B2	Non-petrochemically derived cationic emulsifiers and related compositions and methods The invention includes a neutralized amino acid ester emulsifier, emulsions and compositions containing the emulsifier, and related methods. The emulsifier is a neutralized amino acid ester that is a reaction product of a neutral amino acid with a fatty alcohol and is represented by formula (I): wherein R1 is an alkyl group that has 6 to 24 carbon atoms; R2 is an alkyl group that has 6 to 36 carbon atoms; and the amine group of the amino acid is neutralized with an acid. The emulsifier is cationic. Also included are stable emulsions and compositions, preferably personal care compositions, that include the emulsifier and which may have pH levels of 5.5 or greater. Encompassed within the scope of the invention are methods of increasing the substantivity of a composition to a negatively charged substrate using the emulsifier, methods of emulsifying and methods of preparing a personal care composition using the emulsifier.
US11207246B2	Glass ionomer compositions and methods including inorganic fibers Disclosed herein are curable glass ionomer compositions that include a first paste and a second paste, and methods for using the disclosed compositions. The first paste includes water, a polyacid, and a non acid-reactive filler. The second paste includes water and an acid-reactive filler. At least one of the first paste and the second paste further includes substantially crystalline inorganic fibers. In some embodiments, the water content of the first paste and the second paste of the paste/paste GI composition disclosed herein is less than 20% by weight, based on the total weight of the composition.
US11207245B2	Composite for dental pattern resin To provide a composite for a dental pattern resin whose shrinkage when curing and expansion when heated can be both suppressed as its usability is kept, the composite for a dental pattern resin includes a liquid formulation and a powder formulation, wherein the liquid formulation includes a polymerizable monofunctional (meth)acrylate, a polymerizable polyfunctional (meth)acrylate, and a polymerization accelerator, and the powder formulation includes more than 5 mass % of a (meth)acrylate copolymer on the basis of the total powder formulation.
US11207244B2	Baby bottle with flexible nipple regions According to a first embodiment, a feeding bottle comprises a vessel, collar, and nipple. The nipple comprises a base portion, a teat portion, an areola portion allowing movement of the teat portion towards and away from the base portion. According to a second embodiment, a feeding bottle comprises a vessel, collar, nipple and handle portion removeably secured to the vessel by the collar. The invention includes a flexible region or regions to provide a more natural feeding by closely mimicking the human breast.
US11207236B2	Method and system for providing information to a user A method for providing information to a user, preferably including: determining environmental information; determining a set of features based on the information; determining output parameters based on the features; and controlling a sensory output system to generate outputs based on the output parameters. A sensory output device, preferably including a plurality of sensory output actuators. A system for providing information to a user, preferably including one or more: sensory output devices, sensors, and computing systems.
US11207232B2	Magnetic suspension system A magnetic suspension system for a medical device is provided. The magnetic suspension system comprises a support structure having an area provided with a ferromagnetic characteristic, and a carriage comprising a magnet exerting a magnetic attraction force between the carriage and the support structure. The carriage comprises a friction reducing device and a drive device configured to drive a motion of the carriage upon the support structure in an arbitrary predetermined direction, the drive device being separate from the friction reducing device.
US11207229B2	Care bed combining wheelchair The invention discloses a care bed including a bed frame and a wheelchair. A head panel, a tail panel, a foldable first lateral connecting portion and a second lateral connecting portion of the bed frame constitute an accommodating space of the bed frame. The bed frame has a notch formed at the folded first lateral connecting portion. The wheelchair is moved by the carriage base into the accommodating space through the notch. The backrest, the first armrest, the second armrest, the leg-rest and the footrest of the wheelchair are regulated into a co-plane with the seat to constitute a mattress. The mattress fits the accommodating space of the bed frame.
US11207227B1	Human stabilization platforms and related mattresses Mattresses for human stabilization may include a mass of foam material. A cover including a fabric material may at least partially surrounding the mass of foam material. Head blocks including a foam material may be located proximate to one end of the mattress. The fabric material of the cover may at least partially cover the head blocks, and the head blocks may be foldable relative to the mass of foam material to enable the head blocks to be positioned against lateral sides of a person's head. Human stabilization platforms may include a litter having a surface sized and shaped to support a person thereabove. Straps may be configured to restrain a person's head, the straps having releasable connectors at ends thereof. A track may be located on the surface of the litter, and may be configured to receive the connectors to affix the straps to the litter.
US11207226B2	Lightweight human transport device A compact, portable sled for transporting a person comprises a flexible panel, sheet portions and strapping. The flexible panel has head and foot portions, first and second sides, a sled length, and a sled width. The flexible panel is constructed of a wear resistant material for dragging over rough terrain. The sheet portions made of limp material that is less resistant to wear than the flexible panel. One sheet portion is attached to and extends laterally outward from the first side of the flexible panel. Another sheet portion is attached to and extends laterally outward from the second side of the flexible panel. The flexible panel and sheet portions are collapsible to a compact configuration and expandable from the compact configuration to a use configuration in which the person may be received on the sled for transporting. The strapping is used to secure the person in the sled.
US11207224B1	Portable sanitary staging assembly A portable sanitary staging assembly is utilized to place an infant or a baby on while changing a diaper, or to stage an injured person or animal, such as for triage or emergency medical treatment in the field, or for a person or animal receiving medical attention outside of a typical medical environment. A portable sanitary staging assembly includes a sanitary paper dispenser assembly having a dispenser/protector tube dimensioned to receive sanitary paper therein, the dispenser/protector tube having a dispenser slot formed through a portion of the dispenser/protector tube to facilitate dispensing the sanitary paper. A sanitary pad assembly having a main sanitary pad is interconnected to a portion of the sanitary paper dispenser assembly. A cutter mechanism is affixed to a portion of the portable sanitary staging assembly to facilitate removal and disposal of soiled sanitary paper after use.
US11207223B2	Absorbent articles with multi-pieces acquisition layer An absorbent article having a front side, a back side, a longitudinal axis notionally extending in a longitudinal direction from the middle of the front side to the middle of the back side. The absorbent article has a length L measured along the longitudinal axis. The absorbent article comprises a liquid permeable topsheet on the wearer-facing side, a liquid impermeable backsheet on the garment-facing side, an absorbent core between the topsheet and the backsheet, and an acquisition layer comprising two or more discrete longitudinally-orientated stripes of an acquisition material between the topsheet and the absorbent core. The topsheet forms recesses at the surface of the absorbent article in the gaps between the stripes.
US11207213B2	Lacrimal plug inserter A medical instrument and method is described for facilitating lacrimal occlusion. The instrument has two arms for holding a plug being inserted through the punctum, each arm having a distal end and a proximal end. Attached to the proximal end of the arms is a dilator oriented in the opposite direction along the longitudinal axis of the instrument. The instrument is conveniently rotated in the hand of the practitioner to alternately present the functioning end of the instrument as either the distal end of the arms (for holding a plug) or the distal end of the dilator (for enlarging the punctum prior to attempting to inserting the plug). The instrument has a means for moving the two arms near to each other and away from each, and a means for holding the two arms near to each other without requiring closing pressure applied by the practitioner.
US11207211B2	Lacrimal drug delivery device A lacrimal drug delivery device includes a reservoir configured to hold a drug. The reservoir is moveable between a relaxed state and an expanded state. A connector is fluidly coupled to the reservoir and a lumen is formed in the connector wherein the drug is configured to flow from the reservoir to an delivery site through the lumen. A hydrogel is within the lumen and configured to absorb the drug from the reservoir and deliver the drug from the lumen at the delivery site. The hydrogel includes a first section which absorbs the drug at a first rate of absorption. A delivery guide is detachably coupled to the reservoir to deliver the reservoir into a lacrimal sac of a patient.
US11207210B2	Device and method for fractional RF treatment of the skin A system and method for treating the skin by heating at least one discrete skin volume, comprising at least one treatment tip reversibly connectable to at least one applicator. The treatment tip comprises one or more electrodes, with the electrodes having one or more spaced apart protruding conducting elements. The protruding conducting elements are characterized by dimensions of height A and hypotenuse B, where the ratio A/B is in a predetermined range, and the protruding conducting elements penetrate the skin surface at discrete locations. The electrodes are configured to apply energy to skin volumes around the discrete locations so as to heat the skin volumes. The applicator comprises an energy generator configured to apply energy to the skin volumes by means of the electrodes and the spaced apart protruding conducting elements.
US11207209B2	Intrauterine device with retrieval thread An intrauterine contraceptive system may include a contraceptive intrauterine device, a retrieval thread permanently attached to the intrauterine device and an insertion device for inserting the intrauterine device into a uterus. The system may also include a release thread releasably coupled with the intrauterine device. The intrauterine device may be deployable out of a distal end of the insertion device and may be configured to change from a delivery configuration when housed in the insertion device to a deployed configuration when deployed in a uterus. The retrieval thread and the optional release thread may be at least partially housed within the insertion device during insertion of the intrauterine device into the uterus. The release thread may extend from the intrauterine device through the insertion device to an attachment point at or near a proximal end of the insertion device.
US11207206B2	Fluid removal device A urine removal device includes a pouch with a proximal opening that provides access to an internal compartment of the pouch that is suitable to contain urine. A fluid diverter system is disposed inside of the pouch and extends from the proximal portion of the pouch, where it interfaces via an outlet conduit member to the environment outside of the pouch, to the distal end of the pouch where it draws in urine from the pouch. The pouch has at least one air port to allow air flow through the device to support suction that is applied inside of the pouch. The fluid diverter system has at least one conduit member configured to draw urine from the distal portion of the pouch up to the proximal end of the pouch, and into the outlet conduit member where it exits the fluid collection device.
US11207201B2	Thumb orthosis An orthosis for fastening to a human hand for immobilizing the carpometacarpal joint and metacarpophalangeal joint of the thumb of the hand has a stiff body which can be of multi-piece or single-piece design. The rigidity of the body enables the latter to support, to stabilize and to immobilize the hand and dimensional stability is provided such that the body can be placed in a simple manner with a defined shape onto the hand.
US11207197B2	Orthopaedic surgical instrument for total hip arthroplasty and associated orthopaedic surgical method of use An orthopaedic surgical instrument includes an assembly collar having a cavity extending between a superior opening and an inferior opening. The cavity is sized to receive a tapered trunnion of an implanted femoral stem. A bore extends between an inferior end and a superior end of the assembly collar and is configured to align with an implant bore formed in the implanted femoral stem. The bore and the implant bore are configured to receive a fastener to secure the assembly collar to the implanted femoral stem. A method of utilizing the orthopaedic surgical instrument is also contemplated.
US11207196B2	Devices and methods for bone fixation Devices and methods for bone fixation including a bone fixation system including a bone plate or intervertebral spacer including a plurality of apertures dimensioned to receive bone fasteners and at least one polymeric element capable of transitioning from a solid state to a flowable state. The polymeric element transitions to a flowable state as a result of exposure to ultrasonic vibration. The polymeric element is placed on the bone plate or intervertebral spacer adjacent a fastener in an aperture and acts to prevent rotational and/or translational movement of the fastener relative to the bone plate or intervertebral spacer.
US11207193B2	Oblique expanding fusion cage device and method An oblique expanding fusion cage device including a body with a superior portion and an inferior portion. The superior portion and the inferior portion have a proximal end and a distal end. The fusion cage device also includes a pathway, an opening, and an expanding member. The pathway travels from the proximal end to the distal end of the device between the superior and inferior portions. The opening in the proximal end of the body enables access to the pathway. The expanding member may be re movably inserted into the opening and is moveable toward the distal end of the body, wherein the expanding member engages the superior portion and the inferior portion as the expanding member moves distally within the pathway.
US11207185B2	Splitting attachment for graft containment cage A bone graft containment device includes a body extending longitudinally from a first end to a second end. The body is defined via a strut framework sized and shaped to correspond to an outer surface of a target bone. The strut framework defines an interior space configured to receive a bone graft or bone graft substitute material. The device also includes a first grasping structure and a second grasping structure extending from an exterior of the body. The first and second grasping structures are configured to receive a bone fixation plate therebetween.
US11207184B2	Treatment catheter member with encircling function A catheter member for interacting with a circumferential tissue structure includes: an elongate primary catheter having at least one inner lumen and extending along a longitudinal axis; first and second elongate secondary catheters, each having an inner lumen, and each positionable in an inner lumen of the primary catheter to be moveable relatively thereto and exposable therefrom; and a first flexing mechanism to provide a distal end portion of the first and/or second secondary catheter with a tendency to assume a first secondary bent shape. The distal end portion of the first and/or second secondary catheters is provided so as to be able to be flexed by the first flexing mechanism to form an arm portion substantially transverse to the direction of the longitudinal axis of the primary catheter so as to assume the first secondary bent shape when exposed from a distal end portion of the primary catheter.
US11207182B2	Heart valve therapeutic device A heart valve therapeutic device (1) comprises a coaptation assist valve (20) comprising a conduit (2) with an outer surface (3) for coaption with the native leaflets, and a prosthetic flow valve (5) mounted within the conduit (2) to allow one-way flow through the conduit (2). Support for the coaptation assist valve (20) is provided by a support (10) for positioning the conduit (2) across the native leaflets, and connectors (15) attaching the conduit (2) to the support (10).
US11207181B2	Heart valve sealing devices and delivery devices therefor A valve repair device for repairing a native heart valve of a patient includes a pair of clasps, where each clasp is configured to attach to native valve leaflet. The ends of the pair of clasps can move away from one another to a partially open position when the native valve leaflets open during a diastolic phase of a cardiac cycle, and the ends of the pair of clasps can move toward one another when the native valve leaflets close during a systolic phase of a cardiac cycle.
US11207179B2	Valve insertion tool A valve insertion tool is disclosed. The valve insertion tool may be used in a minimally invasive cardiac surgery. The valve insertion tool includes a housing and a cover, the housing having at least one valve recess and a suture channel. The valve insertion tool is suitable for use in delivering a prosthetic heart valve into a thoracic cavity of a patient during a minimally invasive cardiac surgical procedure. One or more valve insertion tools may be stackable and be pre-loaded with one or more prepared prosthetic heart valves. These one or more valve insertion tools may be packaged as a valve insertion kit.
US11207177B2	Mitral valve prosthesis implantation A heart valve prosthesis and methods of its implantation are described herein. The prosthesis can be implanted in a heart of a patient by positioning an upper support of an anchoring element into a left atrium of the patient. The upper support can expand adjacent to a native valve structure of the patient. Further, the upper support can be moved against the native valve structure in a direction toward a left ventricle of the patient. A lower support of the anchoring element can be positioned into the left ventricle, spaced apart from the upper support, the lower support being separate from the upper support and coupled to the upper support by a flexible connector. Finally, the lower support can expand within the left ventricle, and engagement members of the lower support can engage with tissue of the native valve structure.
US11207176B2	Transcatheter stent-valves and methods, systems and devices for addressing para-valve leakage Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.
US11207175B2	Prosthetic heart valve having improved commissure supports A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.
US11207172B2	Stent designs to cover catheter access site Methods, apparatuses and systems are described for delivering a stent through an access hole of a body lumen and covering up the access hole after deploying the stent, Stents are described that include a stent body defining a body lumen contact surface area and a deployable member configured to deploy from the stent body and increase the body lumen contact surface area of the stent. Deployable members that hinge, unroll, extend, expand, and coaxially translate with respect to the stent body are described. A system for delivering a stent into a body lumen are described that may include a coverage member configured to at least partially cover the hole in the wall of the stent upon withdrawing a tubular member through the hole in the wall of the stent. Coverage members may include a self-sealing membrane, a flap valve, or a hinged valve.
US11207170B2	Systems, methods and devices for embolic protection Embodiments of the present disclosure are directed to systems, methods and devices for providing embolic protection in a patient. In some embodiments, the device is configured for implantation in a body vessel including fluid flow. The device may assume, or be constrained to assume, an undeployed state and a deployed state. In the undeployed state, the device or a portion thereof has a substantially linear shape configured to reside in the lumen of a thin needle having a diameter of less than about 0.5 mm (for example), in the deployed state, the device has a primary axis. When the device is implanted the primary axis is approximately perpendicular to the fluid flow. In some embodiments, the device comprises a thin filament body. In the deployed state the filament takes a helical shape. Emboli that are larger than the distance between consecutive turns or windings of the helix are thus filtered by the device and are prevented from causing deleterious conditions such as stroke or pulmonary embolism. The device may be made of a super-elastic alloy. Thus, the device may transition between the undeployed and the deployed states without plastic deformation. Delivery systems and method for implanting such devices are also disclosed.
US11207168B2	Skirted hernia repair device The present disclosure relates to skirted hernia repair devices which includes at least a first mesh layer having a first side, a second side, and an outer peripheral edge, a skirt mesh layer positioned on the first side of the first mesh layer, the skirt mesh layer having an inner peripheral edge defining an opening in the skirt mesh layer, and, at least one reinforcement member that prevents the skirt mesh layer from inverting.
US11207167B2	Segmented skirted surgical mesh A segmented skirted surgical mesh for use in reconstructing a soft tissue defect, the segmented skirted surgical mesh comprising: a base layer of surgical mesh, the base layer of surgical mesh comprising an outer edge; and a segmented continuous skirt of surgical mesh comprising an outer edge and an inner edge which defines a central opening, the segmented continuous skirt of surgical mesh being secured to the base layer of surgical mesh at the outer edge of the continuous skirt of surgical mesh, and the segmented continuous skirt of surgical mesh comprising a plurality of slits formed in the segmented continuous skirt of surgical mesh, wherein the plurality of slits extend outwardly from the inner edge of the segmented continuous skirt of surgical mesh, whereby to form a plurality of flaps of surgical mesh in the segmented continuous skirt of surgical mesh, such that at least one of the flaps of surgical mesh can be lifted away from the base layer of surgical mesh and secured to soft tissue without causing distortion of the base layer of surgical mesh.
US11207160B2	Intermediate attachment part A substantially tubular intermediate attachment part with a first through-hole for attaching a screw-retained dental prosthetic component or a dental tool to a dental implant or to a dental implant analog, extending along a first longitudinal axis between a first end and a second end. Each end is provided with a set of longitudinal fins intended for snap-fitting into the dental prosthetic component or into the dental tool on the one hand and into the dental implant on the other hand.
US11207159B2	Fixed detachable dental attachment device, assembly and methods of using the same A fixed, detachable dental attachment device has a cap for securing a dental appliance, a ring, and an abutment to attachment to a tooth root or implant. Also described herein are methods of securing a dental appliance in a subject's mouth by means of the dental attachment device. Further described herein is a dental attachment device for immediate load on a provisional denture and then incorporated into the final restoration.
US11207156B2	Method and system for designing and producing dental prosthesis and appliances A virtual model of an intraoral cavity is provided, wherein this process is initialized by a dental clinic, and the design and manufacture of a suitable dental prosthesis for the intraoral cavity is shared between a dental lab and a service center.
US11207155B2	Method for treating exposed dental pulp The invention relates to the application of a composition containing recombinant amelogenin and propylene glycol alginate (“PGA”) on to cut dentin tubules followed by installation of a definitive restorative in a single visit.
US11207153B2	Components for use with a surgical guide for dental implant placement The present invention is a surgical guide for guiding the insertion of a dental implant into a desired location in a patient's mouth. The implant includes a non-rotational structure. The surgical guide includes a structure and a master tube. The structure has a negative impression surface to be fitted on and placed over gingival tissue, bone, and/or teeth in the patient's mouth. The structure includes an opening through which the dental implant is placed. The master tube is located at the opening. The master tube includes indicia for alignment with the non-rotational structure on the implant such that the non-rotational structure of the implant is at a known angular orientation with respect to the master tube. The present invention includes kits of various components used with the surgical guide and with the dental surgery using the surgical guide.
US11207150B2	Displaying a virtual model of a planned instrument attachment to ensure correct selection of physical instrument attachment A virtual model a planned instrument attachment can be provided to ensure correct selection of a physical instrument attachment. An XR headset controller can generate a shape and a pose of the virtual model of the planned instrument attachment based on predetermined information associated with the planned instrument attachment and based on a pose of an instrument relative to the XR headset. An XR headset can display the virtual model on a see-through display screen of the XR headset that is configured to allow at least a portion of a real-world scene to pass therethrough.
US11207149B2	Thermal MRI safe tissue expander port Improvements for use with tissue expanders are provided. A tissue expander includes: a selectively inflatable and deflatable shell that is configured to be implanted; and an access port for selectively inflating and deflating the shell, the access port comprising a sidewall, a base at a first end, and a membrane at a second end opposite the first end wherein the sidewall and the base of the access port are constructed of a material that is non-reactive with a magnetic resonance imaging (MRI) machine; and a structure of the access port is composed of a material that has a rate of temperature change lower than that of human tissue.
US11207146B2	Surgical instrument drive systems with cable-tightening system A surgical instrument drive system is disclosed including a shaft assembly configured to be inserted into and attached to an attachment interface, a pulley drive system, an actuation member comprising a linear rack portion, and a bracket attaching the actuation member to the pulley drive system. The pulley drive system comprises a first cable driver, a second cable driver, a pulley, and a cable supported by the pulley and actuatable by the first cable driver and the second cable driver. The pulley drive system is configured to move the actuation member through an actuation stroke. The bracket comprises a mounting portion and a pawl configured to ratchet relative to the linear rack portion while the actuation member is held in position to allow the bracket to move relative to the actuation member to eliminate previously induced cable slack in the pulley drive system.
US11207136B2	Spinal balance assessment The present application describes computer apparatus and software programs useful to the field of corrective spinal surgery. The apparatus and software implement and facilitate methods for assessing the degree of balance and alignment achieved through corrective measures applied to the spine prior to completing a surgical procedure. The apparatus and software facilitate pre-operative planning and virtual testing of the corrective measures to be applied. The apparatus and software further facilitate intra-operative reconciliation with the pre-operative plan prior to completing the surgery.
US11207132B2	Systems and methods for performing spinal surgery A method is provided for correcting a curvature or deformity in a patient's spine based on the digitized locations of implanted screws. The method is implemented by a control unit through a GUI to digitize screw locations, accept one or more correction outputs, and generate one or more rod solution outputs shaped to fit at locations distinct from the implanted screw locations.
US11207130B2	RF energy enabled tissue debridement device A bipolar electrosurgical device including an outer shaft, an inner shaft, first and second electrode surfaces, and an irrigation channel. The outer shaft defines a lumen, a proximal end and a distal end forming a cutting window. The inner shaft is rotatably disposed within the outer shaft, and defines a distal portion forming a cutting tip. The cutting tip and the cutting window combine to define a cutting implement. The first and second electrode surfaces are electrically isolated, and are formed at the cutting implement. The irrigation channel extends parallel to the outer shaft, and terminates in at least one outlet port. The outlet port is proximally spaced from the cutting window and is located radially outside of the outer shaft. Fluid (e.g., saline) is emitted at the exterior surface of the device near the cutting window and is readily present for interacting with the electrode surfaces.
US11207121B2	Coagulation device comprising an energy control A device (10) for tissue coagulation, in particular for fusion, encompasses an electric source (18), which is connected or which can be connected to electrodes (12, 13) for influencing biological tissue (11) with current. A control unit (22) controls the source (18) during phases I and II of the tissue fusion. These phases I and II correspond to operating phases I, II and III of the device (10). During operating phase I, a monitoring unit (23) determines the energy E1, which is applied into the tissue (11). In the subsequent operating phases II and III, the control unit (22) controls the source (18) by means of the determined energy E1. Such a device turns out to be particularly reliable and to be robust in use.
US11207118B2	Medical system and method of use An instrument and method for applying thermal energy to targeted tissue. An instrument and method for tissue thermotherapy. In one embodiment, a method includes providing a vapor source comprising a pump configured for providing a flow of liquid media from a liquid media source into a vaporization chamber having a heating mechanism, actuating the pump to provide the liquid into the vaporization chamber, applying energy from the heating mechanism to convert a substantially water liquid media into a minimum water vapor level for causing an intended effect in tissue. For examples such levels can comprise at least 60% water vapor, at least 70% water vapor, at least 80% water vapor or at least 90% water vapor for causing an intended effect in tissue.
US11207117B2	Systems and methods to ensure gas egress during cryotherapy The present disclosure relates generally to the field of cryotherapy. In particular, the present disclosure relates to cryotherapy systems that ensure egress of cryogen gas delivered within a patient's body during cryotherapy procedures and, more particularly, sensors for use with cryotherapy systems that include delivery catheters wherein the systems ensure that egress of cryogen gas from the patient's body is possible whenever the catheter is operating.
US11207111B2	Clavicle segmental plate system A medial plate for treating fractures along a clavicle, comprising a plate body including a longitudinal component extending from a first end to a second end and an extension extending from the second end, the second end configured to be mounted over a medial head, a first set of variable angle holes extending through a portion of the longitudinal component including the second end of the longitudinal component and the extension, each of the first set of variable angle holes extending through the plate body along a central axis so that a bone screw is insertable therethrough at a user-selected angle relative to the central axis, and a plurality of combination holes extending through the longitudinal component, each of the plurality of combination holes includes a first portion configured to receive a bone screw at a user-selected angle and a second portion configured to receive a compression screw.
US11207105B2	Device and method for treatment of spinal deformity The present invention generally relates to methods and device for treatment of spinal deformity, wherein at least one tether is utilized to maintain the distance between the spine and the an ilium to (1) prevent increase in abnormal spinal curvature, (2) slow progression of abnormal curvature, or (3) impose at least one corrective displacement and/or rotation.
US11207103B2	Methods and systems for adjusting an external fixation frame A tool for implementing a correction plan in an external fixation frame having a plurality of adjustment elements or screws, for example, generally includes a driver, a motor, a controller, and a processor. The driver is adapted to engage and rotate each of the screws. The motor is coupled the driver and adapted to rotate the driver. The controller is connected to the motor and configured to control operation of the motor. The controller may determine whether the tool is engaged with a strut and which strut is engaged, and may determine how much the strut has rotated, taking into account intentional or unintentional manual rotation of the tool. The tool may also include features to help ensure proper engagement between the drive and the strut. Variations may be provided in which similar functionality is provided with manual rotation of a motorless tool.
US11207098B2	Blunt tip obturator A surgical obturator comprising an elongate shaft extending along an axis between a proximal end and a distal end includes a bladeless tip disposed at the distal end of the shaft. The tip has a blunt point and a pair of shorter side surfaces separated by a relatively longer pair of opposing surfaces to form in radial cross-section a geometric shape that has a longer length and relatively narrower width. The side surfaces and opposing surfaces terminate in end surfaces located proximally from the blunt point. The end surfaces extend radially outwardly from opposite locations of the outer surface. A conical surface facilitates initial insertion of the obturator and the geometric shape facilitates separation of consecutive layers of muscle tissue having fibers oriented in different directions and provides proper alignment of the tip between the layers of muscle.
US11207096B2	Devices systems and methods for cutting and removing occlusive material from a body lumen A vascular device is provided having a catheter body and a rotatable cutter assembly located at the distal end of the catheter body. The cutter assembly has at least one helical cutting surface within a housing that is coupled by a torque shaft to a drive mechanism. A conveyor mechanism helically wound about the torque shaft conveys occlusive material conveyed into the housing by the helical cutting blade further proximally along the catheter body for discharge without supplement of a vacuum pump. The catheter body is manipulated to insert the distal end of the catheter body within a body lumen and advance the distal end of the catheter body toward the occlusive material. The drive mechanism is operated to rotate the helical cutting surface to cut and convey the occlusive material from the body lumen proximally into the housing and to convey the occlusive material conveyed into the housing by the helical cutting surface further proximally along the catheter body by the conveyor mechanism for discharge without supplement of a vacuum pump. The distal end of the catheter body is deflected and rotated to sweep the cutter assembly in an arc about the center axis of the catheter body to cut occlusive material in a region larger than the outside diameter of the cutter assembly.
US11207093B2	Tissue resecting systems and methods A tissue resecting system includes an assembly having first and second tubular members. An electrical motor drive and controller moves the second member to resect tissue received in a window of the first member. A tachometer sends motor drive rotational signals to the controller, and the controller modulates a motor voltage in response to the signals from the tachometer both to drive the second member at a predetermined speed and to calculate resistance to driving the second member at the predetermined speed.
US11207089B2	Apparatus for endoscopic procedures An electromechanical surgical system having an instrument housing for connecting with a shaft assembly, a shaft assembly, and an end effector. The end effector is an articulating end effector and the system includes a cable tensioning system for tensioning the articulation cables. The system includes a clutch mechanism for preventing slippage of a drive cable.
US11207087B2	Guide system with suction A guide catheter for use in treating sinuses, the catheter including a catheter shaft configured to provide suction about a balloon catheter and a distal portion shaped for navigating body anatomy. In one embodiment, the guide catheter includes a valve for sealing the balloon catheter and a vent for controlling suction.
US11207085B2	Surgical instruments and methods of surgically preparing a patient's tibia A method of surgically preparing a proximal end of a tibia includes inserting an intramedullary orthopaedic surgical instrument into a medullary canal of the tibia, securing an attachment device to the intramedullary orthopaedic surgical instrument, attaching a cutting block to the attachment device, resecting the proximal end of the tibia using the cutting block to form a surgically-prepared surface, positioning a tibial base trial on the surgically-prepared surface, and inserting a keel punch through a slot defined in the tibial base trial and into the surgically-prepared surface of the tibia.
US11207084B2	Tool bit for an ultrasonic osteotome Disclosed is a tool bit for an ultrasonic osteotome, comprising a cutting portion (1) located at a front end of the tool bit for an ultrasonic osteotome, a connecting portion (2) located at a rear end of the tool bit for an ultrasonic osteotome and connected with the cutting portion (1). The cutting portion (1) has a grinding part (3) for grinding and a blade part (4) for cutting at a front end thereof, and the grinding part (3) and the blade (4) are integrally formed. The tool bit for an ultrasonic osteotome is of an integral structure formed by grinding part (3) and blade (4). During an operation, a medical worker can use the tool bit for an ultrasonic osteotome for multiple uses with no need to replace the tool bit frequently, thus reducing the operation time, greatly improving the efficiency of surgery, reducing the risk of surgery and the sufferings of a patient. At the same time, the integration of two different types of tool bits can also lower production costs and save manpower and material resources. The tool bit for an ultrasonic osteotome of the disclosure can be operated conveniently and comfortably with high safety.
US11207082B2	Surgical drill type cutting tool A surgical drill type cutting tool includes a shank and an active portion extending in the extension of the shank, with chip areas extending along the active portion, and a ring surrounding a part of the active portion, an inner surface of the ring engaging the active portion without closing off the chip areas, allowing irrigation fluid to provides useful irrigation over most of the length of the active portion of the surgical drill bit.
US11207075B2	Element for producing a vascular clip and vascular clip produced in that way Disclosed are elements for producing a vascular clip and vascular clips produced with these elements. The element is essentially characterized by the fact that it includes a support plate, a clip tab including a gripping face, a unit for securing the clip tab and the edge face of the plate, two substantially identical brackets, each bracket substantially having the shape of a cylinder sector with a thickness Ep and including a through hole with an axis parallel to the generatrix of the cylinder, and a unit to secure the two brackets and the plate in such a way that the axes of the two holes are located on the same straight line perpendicular to the tab and that the opposite faces of the two brackets are set apart from each other by a value equal to the thickness Ep.
US11207074B2	Methods, devices and systems for filling body cavities In various aspects, present disclosure is directed to methods, devices and systems whereby one or more low viscosity fluids may be introduced into a catheter and whereby the one or more low viscosity fluids may be converted into a high viscosity fluid in the catheter, which high viscosity fluid may be delivered from an exit port of the catheter.
US11207063B2	Method and apparatus for passing suture through tissue A suture passer comprising: a hollow tube, the hollow tube comprising a distal end, a proximal end, and a lumen extending from the distal end to the proximal end; and a clamping rod slidably received in the lumen of the hollow tube, the clamping rod comprising a distal end and a proximal end, the distal end being bifurcated into a first arm and a second arm, one of the first and second arms extending distally of the other of the first and second arms and including a clamping surface; wherein at least one of the first arm and the second arm comprises a friction-enhancing surface for facilitating manipulation of a suture via engagement of the suture with the friction-enhancing surface.
US11207062B2	Suture and soft anchor assembly and method of making the same A method of anchoring a suture into a pilot hole in bone utilizing a suture anchor. A lumen-defining circular soft wall, having a first and second end, is slidably engaged to a piece of suture, a first length of which extends from the first end of the wall and is threaded through the lumen from the second end, and a second length of which extends from the second end and is threaded through the lumen from the first end. The suture anchor is introduced into the pilot hole so that the first length and second length of suture material extend out of the pilot hole. The first length and second length are pulled on alternately, thereby permitting the suture anchor structure to slide on the piece of suture material, and to be compacted evenly by the pulling, until the suture anchor is set in the pilot hole.
US11207061B2	Cannula with cap Various devices, systems, and methods are provided for allowing surgical instruments to access a body cavity through an access device, such as a cannula. In one embodiment, a cap can be removably and replaceably coupled to a proximal end of cannula and can have an opening therethrough that communicates with an inner passageway of the cannula. Various surgical elements can be passed through the cap and cannula and into a patient when the cannula is positioned within the patient. The cap can have a side slot formed therein. The slot can be configured to allow surgical elements, such as sutures, to pass through the cap and into the cannula. At least one surgical seal can be in the cap and can be configured to receive surgical elements therethrough.
US11207060B2	Systems and methods relating to medical applications of synthetic polymer formulations Systems, methods and compositions relating to delivering synthetic polymer formulations to the body are described, which can be used by a range of medical personnel including those with minimal experience and training. Under some embodiments, the present invention relates to systems and devices for delivering polymer formulations to a body cavity (e.g. peritoneal cavity) to reduce or stop bleeding. Under some embodiments, an initial percutaneous access pathway is first formed using a delivery device with a probe and needle mechanism that automatically stops the advance of the device upon insertion into a body cavity or space, thus minimizing user error and improving patient safety. The hollow probe then allows transmission of polymer, mixed with gas and/or additional substances, from a holding chamber or canister to flow through the device and hollow probe into the patient's anatomic cavity or space of interest, stopping expansion when the device senses the appropriate pressure. Once reaching the body cavity, the polymer formulation functions to reduce and/or stop bleeding.
US11207058B2	Apparatus for removing intact cells from a surgical site A surgical treatment apparatus comprises a waterjet configured to fragment tissue and provide intact cells such as stem cells with the fragmented tissue. The intact cells can be used in one or more of many ways such as for genetic or other testing, and the intact cells can be identified as stem cells. In many embodiments, the intact cells comprise stem cells. In many embodiments, a waterjet is configured to fragment tissue. The fragmented tissue can be collected with a filter having pores sized smaller than the tissue fragments. In many embodiments cavitation with a waterjet is used to fragment the tissue comprising the intact stem cells. The waterjet may comprise a waterjet immersed in a liquid comprising water so as to form a plurality of shedding pulses. The plurality of shedding pulses can be generated with a frequency sufficient to fragment the tissue. The shedding pulses can generate cavitations that fragment the tissue.
US11207057B1	Nasopharyngeal sample collection devices and methods Kits, devices, systems and related methods for obtaining a nasopharyngeal sample utilize a rinsing fluid supply component and a collecting component, which may be used as separate modules or integrated with a housing to form a handheld unit that may be operated with a single hand. The dispensing component may include a flexible reservoir pump containing a supply of rinsing fluid, and a first nostril interface adapted to engage a first nostril of a patient and guide a stream of rinsing fluid into the patient's nasal cavity. The collecting component may include a collection container and a second nostril interface adapted to engage a second nostril of a patient and collect effluent. An absorbent shield may be arranged on the integrated unit to absorb stray fluid.
US11207053B2	Blood volume assessment using high frequency ultrasound The present disclosure generally relates to using high frequency ultrasound to assess blood volume changes in a subject. A baseline blood volume value can be determined based on a weight of a subject or based on an initial/previous assessment test value. An image taken with the high frequency ultrasound can be retrieved. A test blood volume value can be measured in a field of view of the image. For example, the test blood volume can be determined based on a destruction/replenishment of a contrast agent during imaging by the high frequency ultrasound. A change in blood volume in the subject can be estimated by comparing the test blood volume value to the baseline blood volume value. The estimate of the change in blood volume can be used to assess a condition of the subject.
US11207050B1	Probe and system for use with an ultrasound device Disclosed are ultrasound devices and methods for use in guiding a subdermal probe during a medical procedure. A device can be utilized to guide a probe through the probe guide to a subdermal site. In addition, a device can include a detector in communication with a processor. The detector can recognize the location of a target associated with the probe. The processor can utilize the data from the detector and create an image of a virtual probe that can accurately portray the location of the actual probe on a sonogram of a subdermal area. In addition, disclosed systems can include a set of correlation factors in the processor instructions. As such, the virtual probe image can be correlated with the location of the actual probe.
US11207048B2	X-ray image capturing apparatus and method of controlling the same A method of controlling an X-ray image capturing apparatus, including acquiring, using a camera, a first image by photographing a detector configured to receive X-rays emitted from an X-ray emission surface, generating a second image by performing a correction on the first image, wherein the correction includes changing a first detector shape in the first image to match a second detector shape photographed in a direction perpendicular to the X-ray emission surface, and displaying the second image.
US11207045B2	Systems and methods for estimating healthy lumen diameter and stenosis quantification in coronary arteries Systems and methods are disclosed for predicting healthy lumen radius and calculating a vessel lumen narrowing score. One method of identifying a lumen diameter of a patient's vasculature includes: receiving a data set including one or more lumen segmentations of known healthy vessel segments of a plurality of individuals; extracting one or more lumen features for each of the vessel segments; receiving a lumen segmentation of a patient's vasculature; determining a section of the patient's vasculature; and determining a healthy lumen diameter of the section of the patient's vasculature using the extracted one or more features for each of the known healthy vessel segments of the plurality of individuals.
US11207043B2	Myocardial CT perfusion image synthesis The present invention relates to image processing devices and related methods. The image processing device (10) comprises a data input (11) for receiving spectral computed tomography volumetric image data organized in voxels. The image data comprises a contrast-enhanced volumetric image of a cardiac region in a subject's body and a baseline volumetric image of that cardiac region, e.g. a virtual non-contrast image, wherein the contrast-enhanced volumetric image conveys anatomical information regarding coronary artery anatomy of the subject. The device comprises a flow simulator (12) for generating, or receiving as input, a three-dimensional coronary tree model based on the volumetric image data and for simulating a coronary flow based on the three-dimensional coronary tree model. The device comprises a perfusion synthesis unit (13) for generating a perfusion image representative of a blood distribution in tissue at at least one instant in time taking at least the baseline volumetric image and said coronary flow simulation into account.
US11207041B2	X-ray CT system and medical processing apparatus An X-ray CT system according to an embodiment includes processing circuitry configured to: execute first scanning of acquiring a first subject data set corresponding to first X-ray energy by irradiating a first region of a subject with X-rays; execute, after the first scanning, second scanning of acquiring a second subject data set corresponding to second X-ray energy and a third subject data set corresponding to third X-ray energy different from the second X-ray energy by irradiating a second region included in the first region with X-rays; and perform material decomposition among a plurality of reference materials based on: a fourth subject data set obtained based on the first subject data set and one of the second subject data set and the third subject data set; and the other of the second subject data set and the third subject data set.
US11207040B2	Dental imaging apparatus with improved patient positioning The invention concerns a dental imaging apparatus comprising: —a support frame, —a movable gantry that comprises two opposite arms respectively supporting an x-ray source and an x-ray sensor facing the x-ray source, —a movable patient positioning arm connected to the support frame, —two cameras positioned on the gantry arm supporting the x-ray source and on the positioning arm so as to respectively acquire side and front images of a patient's head, —a display assembly configured to simultaneously display in real time a side image and a front image of the patient's head taken by the two cameras.
US11207036B2	System and method for cabinet x-ray systems with automatic specimen/sample alert The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and an optical camera for the production of organic and non-organic images. The computing device receives data including video data from an optical camera, a laser detector, an infrared detector, an ultrasonic detector, or a weight scale or pressure sensor, and determines automatically, based on the resultant data, if a sample/specimen has been left in the sample chamber. In particular, the disclosure relates to a system and method with corresponding apparatus for automatic detection if a sample/specimen has been left in the sample chamber without having to open the chamber door.
US11207035B2	Sensor-based patient treatment support A framework for sensor-based patient treatment support. In accordance with one aspect, one or more sensors are used to acquire sensor data of one or more objects of interest. The sensor data is then automatically interpreted to generate processing results. One or more actions may be triggered based on the processing results to support treatment of a patient, including supporting medical scanning of the patient.
US11207034B2	Self-calibrating systems and methods for blood pressure wave form analysis and diagnostic support Indirect, oscillometric, digital blood pressure monitoring systems and methods enabling self-calibration to obtain absolute blood pressure values using algorithmic analysis of arterial pressure pulses to establish an oscillometric profile and compensate for intervening effects on digital arterial pressure. Proper algorithmic analysis is dependent upon proper positioning and maintained engagement of a digital cuff on the digit of a user and subsequent hydraulic coupling of the cuff to the arteries within the digit.
US11207029B2	Method for denoising time series images of a moved structure for medical devices Embodiments provide a method for denoising time series images of a moved structure for a medical device. A movement detector detects the moved structure. The movement detector obtains a measurement of the similarity of two images that each represent the same section of the moved structure. The two images originate from two different time series images. A ratio between spatial and temporal denoising is defined for the section as a function of the measurement of the similarity.
US11207028B2	Method and system for monitoring physiological signals/health data, defibrillation, and pacing in the presence of electromagnetic interference A system and method adapted for at least one health-related application selected from physiological monitoring, defibrillation, and pacing in the presence of electromagnetic interference (EMI) using the time-domain features of EMI patterns and physiological waveforms. The invention enables EMI detection and identification in a plurality of signals, including various physiological signals, which may contain both physiological information and EMI-generated artifacts. The system utilizes adaptive and versatile modular architecture with a set of modules for various filtering, conditioning, processing, and wireless transmission functions, which can be assembled in different configurations for different settings. In some preferred embodiments, the method and system of this invention are incorporated into (or attached to) an external cardiac defibrillator/monitor or cardiac pacing device. Other preferred embodiments include a wireless monitoring system that provides reliable wireless data transmission during patient table (bed) movement.
US11207024B2	Vascular imaging apparatus and vascular imaging method A vascular imaging apparatus and a vascular imaging method are disclosed. The vascular imaging apparatus includes: a light source device, an image acquisition device, a projection device and an image processor. The light source device is configured to emit visible light and infrared light to a body portion to be tested in a time-sharing manner; the image acquisition device is configured to receive the visible light and the infrared light reflected by the body portion to be tested to acquire a visible image and an infrared image respectively; the image processor is configured to perform image processing on the infrared image and the visible image, to acquire a vascular enhancement image of the body portion to be tested; the projection device is configured to project the vascular enhancement image onto the body portion to be tested.
US11207022B2	System and method for determining sleep stages based on cardiac activity information and brain activity information in EEG signals The present disclosure pertains to a system configured to determine sleep stages in a subject based on cardiac artifact information and brain activity information in EEG signals. Cardiac artifacts present in EEG signals can cause erroneous sleep stage determinations which may result in inopportune sensory stimulation during sleep, no stimulation at all, discarding long periods of EEG signal information, and/or other events. The present system enhances real-time sleep stage determinations compared to prior art systems and/or provides other advantages because the present system determines the current sleep stage of the subject based on both cardiac activity information and brain activity information included in the EEG signals.
US11207021B2	Methods and systems for labeling sleep states A system, computer-readable storage medium, and a method capable of, directly or indirectly, estimating sleep states of a user based on sensor data from movement sensors and/or optical sensors.
US11207020B2	Fetal monitoring hub In the present invention, a system and associated method is provided for monitoring fetal vital parameters. The system includes a base unit, a monitoring hub including a digital signal processor/controller and operably connected to the base unit by a single channel digital signal protocol cable, e.g., a USB cable, and a number of fetal monitoring sensors operably connected to the monitoring hub. The controller processes the signals from the sensors into a single USB protocol which can be sent along a single cable to the base unit. The USB cable allows power to be supplied to the hub in order to charge a battery used to operate the hub and the sensors connected to the hub when disconnected from the base unit to allow the patient using the hub to move freely about the base unit, with all sensor signals from the hub being wirelessly transmitted to the base unit.
US11207018B2	Stimulation progamming aid using a sensory projection This document discusses, among other things, systems and methods to map an electrical waveform to a user-perceivable input. Some system examples include at least one electrode configured to sense neural activity in a patient, a mapping controller configured to receive an electrical waveform from the at least one electrode and map the sensed neural activity to a user-perceivable output based on the sensed neural activity, and a user interface operably connected to the mapping controller and configured to provide the user-perceivable output to a user.
US11207015B2	Systems and methods for processing and displaying patient electrocardiograph data A method is disclosed for displaying patient ECG data. The method includes receiving ECG data including an ECG waveform; receiving analyzed ECG data including arrhythmic events; generating an indicia of the detected arrhythmic event; and displaying the indicia of the detected arrhythmic event in relation to the ECG waveform at a position associated with a time of the detected arrhythmic event. A system for displaying patient ECG data is also disclosed.
US11207014B2	Automatic sensor selection Automatic electromyography (EMG) electrode selection for robotic devices is disclosed. A plurality of signals from a corresponding plurality of sensors coupled to a skin of a user is received. For each pair of at least some pairs of the plurality of sensors, a sensor pair signature is generated based on differences in signals that are generated by the respective pair of sensors. Each of the sensor pair signatures is compared to a predetermined sensor pair signature to identify a particular pair of sensors. A signal difference between two signals generated by the particular pair of sensors is subsequently utilized to generate a command to drive a motor.
US11207013B2	Systems and methods for estimating a volume of a hollow organ The present disclosure relates generally to estimating an interior diameter of a hollow organ. As such, one aspect of the present disclosure relates to a system that can include a light-based distance sensor and a device housing the light-based distance sensor located within the hollow organ. The light-based distance sensor can include an emitter and a detector. The emitter can transmit a conical beam of light to an inner surface of a hollow organ. The detector can receive a portion of the light back-reflected from the inner surface of the hollow organ. The device can determine a volume of the hollow organ based on a signal related to the back-reflected portion of the light, which can be based on a distance between the light-based distance sensor and the inner surface of the hollow organ.
US11207011B2	Systems and methods for assessing user physiology based on eye tracking data Systems and methods are disclosed for assessing user physiology via eye tracking data. One method includes determining a plurality of visual assessments; determining, for each assessment of the plurality of visual assessments, a data schema, where at least one data schema is associated with more than one assessment of the plurality of visual assessments; storing the determined data schema; receiving user eye tracking data associated with a selected visual assessment of the plurality of visual assessments; determining, of the stored data schema(a), a selected stored data schema associated with the selected visual assessment; categorizing the received eye tracking data based on the selected stored data schema; computing quantitative data based on the categorized data and data related to one or more individuals other than the user; generating a report of user physiological function based on the computed quantitative data; and outputting the report to a web portal.
US11207007B2	Apparatus and method for creating a stable optical interface A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.
US11207004B2	Apparatus for collecting fingerprints and buccal swabs Disclosed are devices and methods for collection, labeling and matching biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature such as a fingerprint or footprint of an individual. Such devices and methods are used in forensic, human identification, paternity, tissue typing, and screening technologies to rapidly process an individual's identity, determine the identity of an individual along with the genotype profile of the individual.
US11207002B2	Fetal health monitor A wearable sensor apparatus is disclosed that includes a flexible substrate adapted to be coupled with a skin surface of an expectant mother. A conductor is disposed on the flexible substrate. The conductor can include micron-scale invaginations. The conductor can be capable of repeatable variation in resistance when subject to a strain. Also disclosed is a system for monitoring the health of a fetus in utero that includes a wearable sensor apparatus. The wearable sensor apparatus is configured to output a signal responsive to an electrical input. The system includes a computing system with one or more hardware processors. The computing system is programmed to implement a signal processing module configured to access the output signal from the wearable strain gauge and generate an output indicative of health of the baby in utero. The output can be based in part on the received output signal and previously stored correlations between signal data from the wearable strain gauge and observations of the system or of the mother. A user interface module can be provided and can be configured to display an output indicative of health of the baby in utero.
US11206999B2	Flexible instrument channel insert for scope with real-time position tracking An apparatus, system and method for determining a position of an instrument (100) includes a sheath (104) configured to fit within an instrument channel of a medical scope. An optical fiber (112) is disposed within the sheath and a plurality of sensors (106) is integrated in optical fiber. The sensors are configured to measure deflections and bending in the optical fiber. A fixing mechanism (140) is sized to fit within the instrument channel in a first state and fixes the sheath within the instrument channel in a second state such that the fixing mechanism anchors the sheath and the optical fiber so that the deflections and bending in the optical fiber are employed with a pre-procedural volumetric image to determine a position of the instrument.
US11206998B2	Optical tracking system for tracking a patient and a surgical instrument with a reference marker and shape measurement device via coordinate transformation An optical tracking system may comprise a reference marker unit stationarily disposed relative to a patient, a shape measurement unit configured to measure the three-dimensional shape of a specified part of the patient corresponding to a three-dimensional image, a tracking sensor unit configured to sense the reference marker unit and the shape measurement unit, and a processing unit. The processing unit may acquire a coordinate transformation relationship between the reference marker unit and the tracking sensor unit and a coordinate transformation relationship between the shape measurement unit and the tracking sensor unit based on a sensing result of the tracking sensor unit, acquire a coordinate transformation relationship between the specified part of the patient and the shape measurement unit based on a measurement result of the shape measurement unit, and define a coordinate system of the patient relative to the reference marker unit from the acquired coordinate transformation relationships.
US11206990B2	Deep tissue flowmetry using diffuse speckle contrast analysis Blood flow rates can be calculated using diffuse speckle contrast analysis in spatial and time domains. In the spatial domain analysis, a multi-pixel image sensor can be used to detect a spatial distribution of speckles in a sample caused by diffusion of light from a coherent light source that is blurred due to the movement of scatterers within the sample (e.g., red blood cells moving within a tissue sample). Statistical analysis of the spatial distribution can be used to calculate blood flow. In the time domain analysis, a slow counter can be used to obtain time-series fluctuations in light intensity in a sample caused by diffusion of light in the sample that is smoothened due to the movement of scatterers. Statistical analysis of the time-series data can be used to calculate blood flow.
US11206987B2	Method and apparatus for concurrent imaging at visible and infrared wavelengths A method of operating a fluorescent imaging system during an open surgery procedure includes concurrently illuminating a tissue with NIR excitation light and visible light, wherein NIR fluorescent light is emitted from the tissue and collecting the NIR fluorescent light and reflected visible light that is reflected from the tissue. The method also includes blocking at least a portion of the NIR excitation light reflected from the tissue and attenuating the reflected visible light. The method further includes imaging, using a camera, the NIR fluorescent light and the attenuated reflected visible light.
US11206986B2	Miniature quantitative optical coherence elastography using a fiber-optic probe with a fabry-perot cavity A miniature quantitative optical coherence elastography system with an integrated Fabry-Perot force sensor for in situ elasticity measurement of biological tissue is provided. The technique has great potential for biomechanics modeling and clinical diagnosis. The qOCE system contains a fiber-optic probe that exerts a compressive force to deform tissue at the tip of the probe. Using the space-division multiplexed optical coherence tomography signal detected by a spectral domain optical coherence tomography engine, probe deformation in proportion to the force applied is quantified, as well as the tissue deformation corresponding to the external stimulus. Simultaneous measurement of force and displacement allows for calculation of Young's modulus from the biological tissue. The provided system has had its effectiveness validated on tissue mimicking phantoms, as well as biological tissues, with the advantages of being minimal invasive and also not requiring the use of external agents or substantial pre-measuring preparation.
US11206985B2	Non-invasive optical detection systems and methods in highly scattering medium A non-invasive optical detection system and method are provided. Sample light is delivered into a target volume of interest, whereby the sample light is scattered by the target volume of interest, resulting in a sample light pattern that exits the anatomical structure. Reference light is combined with the sample light pattern to generate at least one interference light pattern, each of which may have a time varying interference component that integrates to a first value in the absence of the physiological event, and that integrates to a second greater value in the presence of the physiological event. Intensities of spatial components of each interference light pattern are detected during a measurement period. A function of the detected spatial component intensities of the interference light pattern(s) is analyzed, and a presence of the physiological event in the target volume of interest is determined based on the analysis.
US11206979B2	Use of a progressive compression encoding of physiologic waveform data in an implantable device to support discontinuing transmission of low-value data An external data retrieval apparatus receives a low resolution version of a physiological signal from an active implantable medical device and determines if the physiological signal represents a clinically significant event. The apparatus provides an indication of such determination to the implantable medical device. If the physiological signal does represent a clinically significant event, the apparatus receives a full download of the physiological signal from the implantable device.
US11206977B2	Vision test for determining retinal disease progression The present invention provides a reading test to measure vision loss. In one embodiment, the vision loss is due to disease progression. The tests are useful in evaluating the effects of intervention in vision deterioration. The tests are non-invasive, simple, quick, sensitive, reproducible, and easy to administer. The tests measure the subject's reading speed and accuracy under defined conditions of illumination and contrast. The results of these tests may be used to determine if treatment of a disease should be initiated, terminated, altered, or remain unchanged.
US11206976B2	Method and system for simultaneous decomposition of multiple hyperspectral datasets and signal recovery of unknown fluorophores in a biochemical system A system and method are for analyzing fluorescence of fluorophors in an eye using a non-negative matrix factorization (NMF) method. The NMF method may be initialized with Gaussian mixture model fits and may optionally be constrained to provide identical abundance images for data obtained in response to two or more excitation wavelengths.
US11206973B1	Laryngoscope A laryngoscope that includes a low-profile, straight laryngoscope blade that is thin and tapered in width and height, and designed to be intuitive in use and function. A distal tip of the blade may be configured to be placed in the anterior oropharynx with the angled camera (e.g., 10 degrees-40 degrees), thereby providing views of the airway and facilitating blade advancement. Real-time image data collected during a laryngoscopy may be communicated to a medical professional for immediate and ongoing feedback during a laryngoscopy or communicated to an electronic medical record. The laryngoscope provides first responders and airway managers of varying abilities a unique, portable, wireless laryngoscope to optimally manage airways and provide the greatest likelihood of safe, atraumatic airway access. The laryngoscope with the transformational laryngoscope blade design having an angled camera and wireless video forms a singular, effective instrument for airway managers and medical professionals.
US11206971B2	Optical spectroscopy circuitry for assessing ear health A diagnostic tool, such as an otoscope or other hand-held diagnostic device features a handle, a head portion and a circuit. The handle includes a controller and the head portion includes one or more optical spectroscopy (OS) components including at least one light detection element. The circuit includes one or more portions configured to be contorted at acute through reflex angles while maintaining electrical connectivity between the controller and the one or more OS components. The circuit includes a first contact area for the at least one light detection element.
US11206968B2	Actuation handle for accessory devices The present disclosure provides an actuation device that comprises: (a) a device body that comprises a first fixation mechanism configured to affix a proximal end of a first elongate member of an accessory device to the device body, (b) an actuator that comprises an operable mechanism and a second fixation mechanism configured to affix a proximal end of a second elongate member of the accessory device to the actuator, wherein the operable mechanism is configured to move the second elongate member relative to the first elongate member, and (c) a fastener configured to attach the device body to an endoscope. The present disclosure further provides endoscopic systems comprising an actuation device of this type in an assembly with an endoscope and an accessory device, and also provides kits that comprise an actuation device of this type and one or more accessory devices.
US11206967B2	Compact binocular image capture device An image capture device includes a plurality of stacked ceramic circuit boards, an image sensor, signal conditioning electronics, and a connector. Each ceramic circuit board is parallel and directly coupled to at least one other circuit board. The image sensor is mounted to a first ceramic circuit board. The signal conditioning electronics are mounted to one or more of the stacked ceramic circuit boards and are coupled to receive electrical signals generated by the image sensor. The image capture device is enclosed by a shaft and the stacked ceramic circuit boards are stacked along a length of the shaft. The connector is mounted to a second ceramic circuit board that is on an opposite side of the plurality of stacked ceramic circuit boards from the first ceramic circuit board. The connector is mounted to a side of the second ceramic circuit board facing away from the first ceramic circuit board.
US11206965B1	Adjustable rack An adjustable rack suitable for storing lids or other items vertically includes a base platform in two sections telescopically attached to one another and having pluralities of slots formed in sidewalls of the base sections. A plurality of dividers are selectively attached to the rack at any of the plurality of slots. A lock allows the base sections to be secured in a selected position which is either extended or collapsed.
US11206962B1	Brushroll and floor cleaner The present disclosure provides a floor cleaner that includes a replaceable component, such as a brushroll or a filter. The floor cleaner has a detection mechanism comprising a magnet on the replaceable component and a Hall Effect sensor positioned to detect the permanent magnet when the replaceable component is correctly installed on the floor cleaner. Operation of one or more electrically-powered components of the floor cleaner is prevented when the permanent magnet is not detected by the Hall Effect sensor.
US11206960B2	Surface cleaning apparatus A surface cleaning apparatus comprises a brushroll that rotates about an axis. The brushroll defines a cylindrical portion and the axis extends centrally through the cylindrical portion. The brushroll also includes a rib that extends in a direction away from the axis. The rib includes a face extending along a line that is collinear with a secant through the cylindrical portion. A brush member extends from the face.
US11206959B2	Systems and methods for transporting bio-waste A remote-controlled vehicle for collecting and transporting bio-waste that is capable of compacting bio-waste, dumping the waste in a variety of ways, and that has a rechargeable battery, among other functions, is disclosed. A system for collecting the bio-waste material also is provided. The system includes a plurality of collection receptacles associated with a structure, each of the plurality of collection receptacles receiving the bio-waste material without the use of water as a carrier. A transport network extends from each of the plurality of collection receptacles to at least one storage receptacle located at the structure. A plurality of vehicles, or carts, is disposed within the transport network and collect the bio-waste material.
US11206955B2	Upright standing travel soap dish The present invention comprises an upright standing soap hosting device with a holder/brackets for soap that rest on and allows the soap to stand and never touch the bottom of the soap dish/case. The hosting device is configured in different sizes to accommodate different shapes and molds of soap.
US11206951B2	Blending apparatus and methods Blending devices can be used to blend material directly in a container such as a disposable container, such as a paper or plastic cup. In some instances, a disposable container can be coupled to an adapter that includes a blade assembly to blend a food product. The food product can be blended directly within the container when the container is coupled to the adapter and supported with a support sleeve that at least partially surrounds an exterior of the disposable container. In further instances, a stand can selectively couple with multiple different sizes of sleeves and disposable containers to the adapter. The food product can be blended directly within the disposable container without causing damage or flex to the disposable container.
US11206946B2	Heat transfer system A heat transfer system and a broiler that includes a heat transfer system include a heat source. The heat transfer system includes a mixing chamber that surrounds the heat source. An air inlet provides a flow of pressurized air into the mixing chamber. The mixing chamber directs the flow of air past the heat source for direct heating of the flow of air by the heat source. The flow of air is further directed out of the mixing chamber through an outlet to impinge upon a food product.
US11206939B2	Methods, apparatus and systems for accepting, returning or exchanging parcels and deliveries This invention involves a novel method, device, system and apparatus to receive return or exchange goods and services at one's doorstep securely. The invention involves a novel security apparatus and a parcel receptacle. The security apparatus is connectable to any fixture, including to one or more parcel receptacles. The parcel receptacles can be of many types. The parcel receptacles can be secured via a physical cable and a security apparatus, or secured via connectivity to the wireless network of a parcel recipient. The parcel receptacles can also be secured via a novel GPS module, accelerometer and other technological devices inside parcel receptacle. The locking mechanism in the security apparatus and/or on the parcel receptacle can be of technological in nature using the latest advancements in wireless technology, or alternatively, involve simple physical lock and key mechanisms. The apparatus allows access to parcels to authenticated users only, and involve many safety features including an audible alarm and other tamper-proof mechanisms to ensure safety of parcels.
US11206932B2	Play yard having adjustable bassinet A play yard includes a frame body having first and second sides, a bassinet, a strap and a connecting unit. The bassinet is disposed between the first and second sides, includes a backrest and has a lower end portion attached to the frame body, and an upper end portion mounted with the backrest. The strap has a fixed end fastened to the first side, and a free end connected to the second side, and supports the upper end portion. The connecting unit connects the free end to the second side such that an effective length of the strap between a portion of the strap disposed within the connecting unit and the fixed end is adjustable to change an inclination of the backrest when the free end moves relative to the connecting unit.
US11206931B2	Convertible bedside bassinet and changing table A convertible bassinet including a mobile support enabling selective movement about a supporting surface and a braking apparatus providing the ability to secure the mobile support in a laterally fixed position on the surface. The mobile support also includes a vertical adjustment mechanism enabling the height of the bassinet to be altered by a user. The bassinet further includes a top perimeter frame with a position actuator for varying the height of the top perimeter frame above a child supporting surface. When in an uppermost position the perimeter frame defines a bassinet. A changing table surface is defined when the perimeter frame is repositioned to a lowermost position. Resilient connectors between the position actuator and the perimeter frame members allow the top perimeter frame to move from the uppermost position to the lowermost position independent of movement of the position actuator.
US11206930B2	Multi-stage linkage interlocking structure of swing dining chair A multi-stage linkage interlocking structure of a swing dining chair comprising a swing arm and a chair body. The chair body comprises a seat and a backrest. A multi-stage included-angle adjustment device is arranged between the seat and the backrest. The swing arm is provided with a mounting base, and the seat is rotatably connected with the mounting base. A first locking device is arranged between the seat and the mounting base for locking the seat. The seat is provided with a second locking device for locking the first locking device. A sliding connection rod in linkage with the backrest is provided for unlocking the second locking device. A third locking device in linkage with the mounting base and interacting with the multi-stage included-angle adjustment device is arranged between the seat and the mounting base. The present disclosure has a simple structure, achieves convenient operation and safety, and avoids mal operation.
US11206927B2	Collapsible rocking chair with improved folding mechanism A chair comprising preferably including a seat frame coupled to a back frame; a seat panel coupled to the seat frame and a back support panel coupled to the back frame; a front leg frame coupled to a back leg frame; a first arm rest coupled at one end thereof to a first segment of the back frame; a second arm rest coupled at one end thereof to a second segment of the back frame; a front leg crossbar coupled between a first segment of the front leg frame and a second segment of the front leg frame; a rear leg crossbar coupled between a first segment of the back leg frame and a second segment of the back leg frame; and an assembly that permits a collapsing the chair from at least an open position to a collapsed position and flexing members that will flex during a rocking of the chair between at least one of a rearward and forward position to the other of the forward and rearward position.

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