Document Document Title
US11155846B2 Methods for reducing contamination during enzymatic hydrolysis of biomass-derived cellulose
Some variations provide a method of enzymatically converting biomass-derived cellulose to glucose, comprising exposing the biomass-derived cellulose to (i) cellulase enzymes, to hydrolyze the cellulose to glucose; and (ii) an external sulfur-containing compound, to deter bacterial and/or yeast contamination during cellulose hydrolysis. In some embodiments, the sulfur-containing compound includes sulfur dioxide or lignosulfonates. When the sulfur-containing compound includes lignosulfonates, the lignosulfonates may also function as an enzyme surfactant to assist hydrolysis, in addition to deterring bacterial and/or yeast growth/contamination. This method may be applied to cellulose-rich solids obtained from the AVAP® fractionation process, the GREEN POWER+® pretreatment process, or any other source of cellulose-rich solids.
US11155844B2 Process for the production of ortho-aminobenzoic acid and/or aniline from fermentable substrate using recombinant yeast
The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.
US11155842B2 Process for preparing sphingolipids
The invention provides a process for preparing sphingolipids, compositions comprising sphingolipids and further components, and for the use of the compositions.
US11155841B2 Method for producing sphingoid base or sphingolipid
A method for producing an objective substance such as sphingoid bases and sphingolipids using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture medium containing an additive that is able to associate with, bind to, solubilize, and/or capture the objective substance, and collecting the objective substance from cells of the yeast and/or the culture medium.
US11155837B2 Methods and microorganisms for making 1,4-butanediol and derivatives thereof from C1 carbons
Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 1,4-BDO are disclosed. For example, genetically modified methanotrophs that are capable of generating 1,4-BDO at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed.
US11155832B2 Adenovectors for delivery of therapeutic genetic material into T cells
The invention provides adenoviral vectors and compositions for the highly efficient transduction of T cells.
US11155831B2 AAV-based conditional expression system
The present invention relates to a cell comprising (aa) a nucleic acid comprising in 5′ to 3′ direction (i) at least one adeno-associated virus (AAV) inverted terminal repeat (ITR) sequence; (ii) a promoter which is capable of being activated by (a) helper polypeptide(s) and optionally (a) helper polynucleotide(s); and (iii) a transgenic coding sequence under the control of said promoter of (aa)(ii); and (ab) a nucleic acid comprising in 5′ to 3′ direction (i) a promoter which is capable of being activated by said helper polypeptide(s) and optionally said helper polynucleotide(s); and (ii) at least one AAV rep gene coding sequence under the control of said promoter of (ab)(i); wherein said cell does not comprise an AAV cap gene and/or is not able to express any AAV cap gene product.
US11155828B2 Specific expression promoters in rice and the use thereof
The present invention provides the specific expression promoters in rice and the application. The present invention applies the promoter in the plant genetic engineering. The sequence of the promoter provided in the present invention is composed of the nucleotide sequence shown in SEQ ID No. 1; the nucleotide sequence shown in SEQ ID No. 2; Or the nucleotide sequence shown in SEQ ID No. 3.
US11155827B2 Methods for generating transgenic plants
This invention provides a method for generating transgenic plants with a low copy number. Plant cells are transformed with polynucleotides containing transcriptional cassettes designed to trigger silencing of a gene which is essential for the plant cell to survive the transformation and regeneration process. The present invention enables the recovery of an increased number of transgenic plants which have only one copy of each desired transcriptional cassette.
US11155825B2 Methods and compositions for generating doubled haploid plants and use of same in breeding
The present invention generally provides methods to generate plants with high frequency of spontaneous haploid genome doubling for use in doubled haploid production. The invention relates to the BUBR1 nucleic acid and protein sequences identified, which are associated with spontaneous haploid genome doubling.
US11155822B2 Transposon that promotes functional DNA expression in episomal DNAs and method to enhance DNA transcription during functional analysis of metagenomic libraries
A transposon (TnC_T7) was developed to partially supply the transcriptional machinery during functional analysis of genomic/metagenomic libraries. This transposon was conceived and constructed to have the ability to integrate randomly into any episomal DNA, allowing the inducible expression of the adjacent DNA regions in both directions. In general, this genetic tool included a kanamycin resistance gene, two bidirectional T7 promoters and the T7RNA polymerase-coding gene, the latter under the regulation of the inducible arabinose promoter (PBAD). The experimental validation confirmed the TnC_T7 potential to be used in functional genomic/metagenomic studies, in order to partially overcome the limitations of the bacterial hosts, which prevent them to recognize most of foreign genes from DNA libraries.
US11155818B2 MicroRNA hsa-miR-665 in cardiac hypertrophy
The present invention refers to human microRNA hsa-miR-665 for the treatment or prevention of heart diseases associated with cardiac hypertrophy and consequent pathological remodeling of the heart, in particular for preventing and/or treating heart failure (HF). Vectors and pharmaceutical compositions comprising said miRNA for the disclosed uses are also within the scope of the present invention.
US11155816B2 Oligonucleotide conjugates
The invention relates to the field of oligonucleotide therapeutics, and in particular to the use of a cleavable, e.g. a phosphodiester region covalently attached to a conjugate, a targeting group or blocking group to enhance the properties of the oligonucleotides, for example to improve the therapeutic index.
US11155814B2 Methods for using DNA repair for cell engineering
Methods for gene editing and predicting non-random editing events are described. The methods use Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems to characterize and manipulate DNA repair outcomes at Cas-initiated double-strand breaks (DSBs) to anticipate functional outcomes.
US11155810B2 Single cell analysis of transposase accessible chromatin
Methods and systems for sample preparation techniques that allow amplification (e.g., whole genome amplification) and sequencing of chromatin accessible regions of single cells are provided. The methods and systems generally operate by forming or providing partitions (e.g., droplets) including a single biological particle and a single bead comprising a barcoded oligonucleotide. The preparation of barcoded next-generation sequencing libraries prepared from a single cell is facilitated by the transposon-mediated transposition and fragmentation of a target nucleic acid sequence. The methods and systems may be configured to allow the implementation of single-operation or multi-operation chemical and/or biochemical processing within the partitions.
US11155809B2 Digital PCR barcoding
Methods, compositions, and kits are provided for nucleic acid analysis, including single cell analysis.
US11155803B2 Adenosine deaminase base editors and methods of using same to modify a nucleobase in a target sequence
The disclosure provides compositions comprising novel adenosine base editors (e.g., ABE8) that have increased efficiency and methods of using these adenosine deaminase variants for editing a target sequence.
US11155793B2 Phytase variants YeAPPA having improved gastric protein resistance and acid resistance, and increased catalytic efficiency
The present invention relates to the field of genetic engineering, particularly to phytase variant YeAPPA having improved pepsin resistance and acid resistance, and increased catalytic efficiency, by substituting Leucine at the 162th site of the sequence set forth in SEQ ID NO.1 with glycine or proline or substituting glutamic acid at the 230th site of the sequence set forth in SEQ ID NO.1 with glycine, proline or arginine, in the benefit of the development of economical feed enzyme industry.
US11155792B2 Highly sensitive optical sensor for polymerase screening
The present invention is directed to a polymerase activity assay that produces a strong optical signal when a primer-template complex is extended to full-length product. The assay uses Cy3 as the molecular beacon and Iowa Black® RQ as the quencher. The signal-to-noise-ratio (STNR) of this donor-quencher pairing is ˜200-fold over background, which is considerably better than other donor-quencher pairs (STNRs ˜10-20-fold). The STNR allows for solution-based monitoring of polymerase activity. Because the sensor functions via Watson-Crick base pairing, the polymerase activity assay may also be used to evolve polymerases to accept xeno nucleic acids as substrates.
US11155791B2 Methods for treating anemia in a subject in need thereof
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
US11155788B2 Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
A biological system for generating and preserving a repository of personalized, humanized transplantable cells, tissues, and organs for transplantation, wherein the biological system is biologically active and metabolically active, the biological system having genetically reprogrammed cells, tissues, and organs in a non-human animal for transplantation into a human recipient, wherein the non-human animal does not present one or more surface glycan epitopes and specific sequences from the wild-type swine's SLA is replaced with a synthetic nucleotides based on a human captured reference sequence from a human recipient's HLA.
US11155787B2 Methods for generating stem cell-derived beta cells and methods of use thereof
Disclosed herein are methods for generating SC-β cells, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
US11155781B2 Maintenance of differentiated cells with laminins
The present disclosure describes methods of maintaining the phenotype of differentiated cells. Generally, the natural environment of the body is replicated for the differentiated cell. The differentiated cell is plated on a cell culture substrate comprising a laminin, such as laminin-521 or laminin-511. The substrate may also contain a cadherin. This maintains the phenotype of the differentiated cell.
US11155779B2 Microfluidic sorting with high gradient magnetic fields using opposing arrays of adjacent magnets
Microfluidic devices are described that include a microfluidic channel, a first array of one or more magnets above the microfluidic channel, each magnet in the first array having a magnetic pole orientation opposite to a magnetic pole orientation of an adjacent magnet in the first array, and a second array of one or more magnets beneath the microfluidic channel, each magnet in the second array having a magnetic pole orientation opposite to a magnetic pole orientation of an adjacent magnet in the second array. The first array is aligned with respect to the second array such that magnetic fields emitted by the first array and second array generate a magnetic flux gradient profile extending through the channel. An absolute value of the profile includes a first maximum and a second maximum that bound a local minimum. The local minimum is located within the microfluidic channel or less than 5 mm away from a wall of the microfluidic channel. Methods of using the new devices are also described.
US11155778B2 Closed system device and methods for gas permeable cell culture process
Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
US11155777B2 Bioreactors with multiple or adjustable-position agitator designs
Described herein are bioreactor support structures configured to be used with containers having different designs, and methods for making and using such bioreactors. The support structures described herein may include two or more agitator motors and control systems or an adjustable-position agitator motor, a removable spacer and/or lid, multiple configurations for ports and probes, and multiple exhaust filter heating blankets. Also described herein are methods of manufacturing a multi-agitator motor or adjustable-position agitator motor bioreactor, as well as methods of modifying an existing support structure to be used with a container not originally designed to be used with the existing support structure, and methods for operating these bioreactors.
US11155774B2 Method and apparatus for generating three-dimensional patterned soft structures and uses thereof
A method for generating a three-dimensional patterned soft structure, including the steps of providing a soft supporting substrate, providing a drop-on-demand system with a device for varying the velocity of the jetted droplets, providing a liquid ink, jetting the liquid ink towards the soft supporting substrate with the drop-on-demand system, controlling an injection depth of the liquid ink into the soft supporting substrate by varying a jetting velocity of the liquid ink; and depositing droplets of the liquid ink over a volume of the soft supporting substrate, thereby generating the three-dimensional patterned soft structure.
US11155773B2 Expedited PCR with stirring
Disclosed are an apparatus and methods for rapid amplification of nucleic acids. More particularly, the present disclosure relates to an apparatus for mixing a reaction solution during amplification of nucleic acids and to methods for amplifying nucleic acids. Also disclosed are methods for lysing cells in a sample and amplifying nucleic acids.
US11155772B2 Compounds for a controlled release of active perfuming molecules
The present invention relates to the field of perfumery. More particularly, it concerns compounds comprising at least one β-thio carbonyl or nitrile moiety capable of liberating an active molecule selected from an α,β-unsaturated ketone, aldehyde or nitrile. The present invention concerns also the use of said compounds in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's compounds. (I) wherein: a) m represents an integer from 1 to 6; b) Pro represents a hydrogen atom or a group susceptible of generating an odoriferous α,β-unsaturated ketone, aldehyde or nitrile and is represented by the formulae (II) or (II′) in which the wavy line indicates the location of the bond between said Pro and the sulfur atom S; and at least one of the Pro groups is of the formula (II) or (II′).
US11155771B2 Method for preparing a liquid washing or cleaning agent using a preservative-free dye solution
A continuous method for preparing a liquid washing or cleaning agent which includes at least one surfactant and at least one dye. In this case, the dye solution used in the method according to the invention is free of preservatives. The present invention also relates to washing or cleaning agents which are obtained by way of the method according to the invention.
US11155770B2 Liquid hand dishwashing detergent composition
The present invention relates to a hand dishwashing detergent composition including a surfactant system and at least one triblock co-polymer of Formula (I): (EO)x-(PO)y-(EO)x wherein each x is independently on average between about 5 and about 50.
US11155768B2 Lubricant oil compositions for automotive gears
A lubricant oil composition for automotive gears includes a lubricant base oil including a mineral oil having a kinematic viscosity at 100° C. of 2.0 to 6.5 mm2/s, a viscosity index of not less than 105 and a pour point of not more than −10° C., and/or a synthetic oil having a kinematic viscosity at 100° C. of 1.0 to 6.5 mm2/s, a viscosity index of not less than 120 and a pour point of not more than −30° C.; and an ethylene/α-olefin copolymer having an ethylene content of 55 to 85 mol %, a kinematic viscosity at 100° C. of 10 to 200 mm2/s, a molecular weight distribution of not more than 2.2, and a melting point in the range of −30° C. to −60° C. The lubricant oil composition for automotive gears has a kinematic viscosity at 100° C. of 4.0 to 9.0 mm2/s.
US11155761B2 Synthetic esters derived from high stability oleic acid
A composition comprising a synthetic ester having a fatty acid mixture including: oleic acid in amount of at least about 85 wt % of the fatty acid mixture; linoleic acid in an amount of about 3 wt % of the fatty acid mixture or less; and linolenic acid in an amount of about 0.5 wt % of the fatty acid mixture or less.
US11155758B2 Method of dosing a system with HCL then evacuating and purging
A method of dosing a system with HCL is provided. The method includes at least two parallel trains. The method utilizes a first operating mode, wherein at least one primary train is actively providing HCL to an end user, and at least one secondary train is either inactive or also providing HCL to the end user. The method utilizes a second operating mode, wherein the least one primary train is evacuating the contents of the train to a disposal system, and the at least one secondary train is providing HCL to the end user. And the system utilizes a third operating mode, wherein the at least one primary train is purging the train, and the at least one secondary train is providing HCL to the end user. The first operating mode, the second operating mode, and the third operating mode are controlled by an electronic monitoring and control system.
US11155757B2 Isomerization process using feedstock containing dissolved hydrogen
A process and system is provided including hydroisomerization reaction zone for production of high octane gasoline blending components that provide high selectivity for producing high octane isomers of light paraffins. A light paraffin feed is enriched by incorporation of dissolved hydrogen, thereby permitting a reaction phase that is liquid or substantially liquid to produce high octane gasoline blending components. Accordingly, a substantially two phase isomerization reactor system is provided, with a hydrogen-enriched liquid feedstock phase and a solid phase catalyst.
US11155751B2 Method of treating subterranean formations with composites having enhanced strength
The strength of a proppant or sand control particulate may be improved by coating the proppant to form a composite. The composite has enhanced compressive strength between about 34 to about 130 MPa and minimizes the spalling of fines at closure stresses in excess of 5,000 psi. Conductivity of the proppant pack in the fractures is further enhanced due to the increase in strength of the particles.
US11155744B2 Coated lost circulation materials and methods of using same
A method of reducing fluid loss includes pumping a wellbore fluid including resin coated solid particulate into a wellbore having fractures therein, the resin coated solid particulate forming a substantially impermeable plug in the fractures. A method of drilling a wellbore includes drilling a wellbore through a formation using a first wellbore fluid; and upon experiencing a fluid loss event to the formation, pumping a second wellbore fluid including resin coated solid particulates into the wellbore.
US11155737B2 Nonflammable refrigerants having low GWP, and systems for and methods of providing refrigeration
The present invention provides a refrigerant composition comprising: (a) from about 65% by weight to about 90% by weight of HFO-1234ze(E); (b) from about 10% by weight to about 35% by weight of HFO-1336mzz (E); and optionally (c) from about 0% to about 4.4% by weight of HFC-227ea for use in a variety of refrigeration applications, including air conditioning and/or refrigeration and particularly cooling products such as fruits, vegetables and beverages without exposing those articles to temperatures below the freezing point of water.
US11155731B2 Composition, its production and use thereof
The present invention relates to a composition, a process for its production, and use thereof. The composition comprises water, a polyurethane polymer and a water-soluble salt of a chelating agent, said polyurethane polymer having a hydrolyzable group, said polyurethane polymer is a reaction product comprising the following reactive components: Component A) an isocyanate, Component B) a compound having an isocyanate-reactive group, wherein said compound comprises at least one group that can be converted to said hydrolyzable group, optionally Component C) an emulsifier, optionally Component D) a solvent, and optionally Component E) a reactive diluent; wherein said water-soluble salt of the chelating agent is present in an amount of from 0.04 to 1.8% by weight, relative to 100% by weight of said polyurethane polymer.
US11155729B2 Graft copolymers and compositions thereof
This invention relates to a graft copolymer comprising: a) a macromonomer, wherein the macromonomer comprises in polymerized form a first monoethylenically unsaturated monomer selected from a group consisting of esters of methacrylic acid and acrylic acid with straight or branched alcohols having 1 to 3 carbon atoms and no more than 5 mole % an addition fragmentation chain transfer agent; and b) at least one side chain on the macromonomer, wherein the at least one side chain comprises at least 95 wt.-% of acrylic acid in polymerized form, and its use for improving the dirt pick-up resistance of a paint or coating.
US11155722B2 Preparation of a coatings formulation with alkali swellable polymer particles
The present invention relates to a process for preparing a coatings composition with an open time additive comprising the steps of a) contacting an aqueous dispersion of alkali swellable polymer particles with a rheology modifier and a binder to form a coatings composition with a VOC of less than 50 g/L; and b) neutralizing the alkali swellable particles with a non-volatile base after or upon contact with the rheology modifier and the binder to form swelled multi-staged polymer particles; wherein the alkali swellable polymer particles comprise a shell having a Tg of not greater than 25° C. and an acid functionalized core; and wherein the core-to-shell ratio is in the range of from 1:3.2 to 1:10. The composition arising from the process of the present invention is useful for improving open time, especially for low VOC coatings applications.
US11155720B2 Water-based aerosol paint
The invention relates to a water based paint composition to be used in a pressurized and sealed aerosol can and which composition contains A) up to 24% w/w of propellant gas which is dimethyl ether (DME); B) up to 76% w/w of coating material, consisting nonvolatile content in the range of 65-95% w/w and volatile content in the range of 5-35% w/w; —which volatile content contains water up to 0-100% w/w and additives, co-solvents and dispersing agents which comprise altogether of 0-9% w/w of volatile liquids, having 0-10% w/w preferably less than 5% w/w of volatile organic compounds (VOC) provided that the aggregate amount of dimethyl ether (DME) and the volatile organic compounds (VOC) in volatile liquids is such that VOC concentration is below 186 g/l (responding about 24% w/w, calculated as DME). In the present invention the nonvolatile content comprises color pigments and possible fillers in the range of 0-30% w/w, polyurethane modified alkyd resin or alkyd resin in the range of 25-99% w/w preferably in the range of 35-90% w/w and additives up to 9% w/w, which resin is present as an emulsified dispersion in water miscible solvent comprising water and dimethyl ether (DME).
US11155716B2 Icephobic coating composition
An icephobic coating composition forms a coating layer that melts ice and snow upon contract and remains durable after several exposures to winter storms. The icephobic coating composition includes about 2.5% to about 12.5% by weight of latex polymer solids; about 30% to about 70% by weight of an inorganic halide salt; about 15% to about 50% by weight water; and about 1% to about 15% by weight of an organic co-solvent selected from glycerin, glycols, and glycol ethers. An alternative icephobic coating composition includes about 1% to about 20% by weight of a solution polymer instead of a latex polymer, and about 10% to about 40% by weight of a VOC-exempt organic solvent instead of the foregoing water and co-solvent.
US11155700B2 Tire puncture sealant
The object of the present invention is to provide a tire puncture sealant having excellent sealing property, storage property, and injection property. The tire puncture sealant of the present invention contains a rubber latex and/or a resin emulsion and a cellulose fiber having a maximum fiber diameter of less than 1,000 nm, the cellulose fiber containing cellulose that optionally has a functional group.
US11155699B2 Nanocellulose composite, and method for manufacturing same
Provided are nanocellulose composite and preparation method thereof. The method comprises preparing cellulose nanofiber, mixing the cellulose nanofiber with a silica precursor in a solvent to attach silica particles to the surface of the cellulose nanofiber, or to form a silica coating layer on the surface of the cellulose nanofiber, and mixing the cellulose nanofiber with the silica particles or the silica coating layer with a polymer. According to the present invention, by using surface vitrification-treated nano cellulose, nanocellulose polymer composites that exhibits high mechanical properties such as impact resistance as well as excellent heat resistance can be prepared.
US11155698B2 Method for the production of a film comprising microfibrillated cellulose and a film comprising microfibrillated cellulose
The present invention relates to a method for the production of a film comprising microfibrillated cellulose, wherein the method comprises the steps of; providing a suspension comprising microfibrillated cellulose, applying the suspension on a substrate to form a fibrous web, wherein the web has a first and a second side, conducting the web to a contact drying equipment wherein the first side of said web is in direct contact with of the contact drying equipment at a temperature above 100° C. whereby the web is at least partly dried forming a film. The invention also relates to a film produced according to the method.
US11155696B2 Preparation and uses of bio-adhesives
The present application relates generally to bio-adhesive components isolated from bio-oil prepared from animal waste, methods of preparation of the bio-adhesive components and uses thereof. Such uses include, but are not limited to, asphalt bio-binders, bio-adhesion promoters, asphalt bio-rejuvenators, asphalt bio-extenders, bio-asphalt as well as uses in roofing, soil stabilization, crack and joint sealing and flooring adhesives.
US11155694B2 Polycarbonate resin composition and optical molded article composed thereof
Provided are a polycarbonate resin composition comprising a polycarbonate resin, a black colorant, a yellow colorant, and at least one ultraviolet absorber selected from the group consisting of a benzotriazole-based compound, a benzophenone-based compound, and a triazine-based compound, and an optical molded article composed thereof.
US11155693B2 Flexible crosslinked cable insulation and methods for making flexible crosslinked cable insulation
Crosslinkable polymeric compositions comprising (a) 10 to 99 weight percent of an ethylene-based interpolymer having the following properties: (i) a density of 0.93 g/cm3 or less, (ii) a high-shear viscosity (V100) at 190° C. and 10% strain of 1,200 Pa-s or less, and (iii) a shear thinning ratio (V0.1/V100) at 190° C. and 10% strain of at least 8; and (b) 0 to less than 10 weight percent of a filler, where the ethylene-based interpolymer is not prepared in a high-pressure reactor. Such crosslinkable polymeric compositions may be employed as insulation layers in flexible power cables.
US11155689B2 Polymeric material for an insulated container
A formulation includes a polymeric material, a nucleating agent, a blowing, and a surface active agent. The formulation can be used to form a container.
US11155687B2 High Tg epoxy formulation with good thermal properties
Varnish compositions and prepregs and laminates made therefrom wherein the varnish compositions include at least one first epoxy resin and at least one second epoxy resin that includes a bisphenol-A novolac epoxy resin and a harder wherein the at least one first epoxy resin and the at least one second bisphenol-A novolac epoxy resin are present in the varnish at a weight ratio ranging from about 1:1 to about 1:3.
US11155685B2 Acrylic emulsions modified with functional (meth)acrylates to enable crosslinking
The present invention provides a method for crosslinking an acrylic emulsion with a (meth)acrylate monomer or a (meth)acrylate oligomer including adding a base acrylic emulsion to a vessel, adding at least one (meth)acrylate crosslinker to the vessel, incorporating the at least one (meth)acrylate crosslinker into the base acrylic emulsion to create a two-phase system including water and a phase including crosslinkers of the at least one (meth)acrylate crosslinker inside acrylic emulsion particles of the base acrylic emulsion, applying the two-phase system to a surface, and curing the two-phase system to create a final system including a continuous film and crosslinked crosslinkers.
US11155682B2 Continuous dehydration method and method for producing polyarylene sulfide
The continuous dehydration method for a raw material mixture to be used in the production of PAS includes supply and dehydration of the raw material mixture and extraction of the raw material mixture having a water content reduced by the dehydration, the supply, dehydration and extraction being carried out concurrently in parallel. A dehydration efficiency index determined according to Equation (1) is not less than 0.3. In Equation (1), the dehydration time is a period of time until a moisture content per mole of the sulfur source in the raw material mixture having a reduced water content reaches not greater than 1.7 mol, including moisture consumed by the hydrolysis of the organic polar solvent. Dehydration efficiency index=[Number of moles (mol) of the sulfur source in the raw material mixture having a reduced water content]/[Dehydration time (hr)×(Total internal volume (L) of the dehydration tanks)2/3]  (1)
US11155680B2 Polymeric materials
A polymeric material has a repeat unit of formula —O-Ph-O-Ph-CO-Ph- I and a repeat unit of formula —O-Ph-Ph-O-Ph-CO-Ph- II wherein Ph represents a phenylene moiety; wherein the repeat units I and II are in the relative molar properties I:II of from 65:35 to 95:5; wherein log10 (X %)>1.50-0.26 MV; wherein X % refers to the % crystallinity measured as described in Example 31 and MV refers to the melt viscosity measured as described in Example 30. A process for making the polymeric material comprises polycondensing a mixture of at least one dihydroxybenzene compound and at least one dihydroxybiphenyl compound in the molar proportions 65:35 to 95:5 with at least one dihalobenzophenone in the presence of sodium carbonate and potassium carbonate wherein: (i) the mole % of said potassium carbonate is at least 2.5 and/or (ii) the following relationship applies the ⁢ ⁢ D 50 ⁢ ⁢ of ⁢ ⁢ said ⁢ ⁢ sodium ⁢ ⁢ carbonate ⁢ ⁢ in ⁢ ⁢ μm mole ⁢ ⁢ % ⁢ ⁢ of ⁢ ⁢ potassium ⁢ ⁢ carbonate = < 4 ⁢ 6 .
US11155675B2 Method of regioselective synthesis of polyesters from asymmetric diols
A method for synthesizing regioregular polyesters, starting from asymmetric diols, may provide the polymer ordered structure and advantageous physical-chemical properties. Such methods can make it is possible to obtain regioregular polyesters having high glass transition temperatures Tg and crystalline properties. In the case in which the asymmetric diols are used in a pure enantiomeric form, with respect to the chiral carbon bound to the secondary hydroxyl, through the above-mentioned method it is possible to obtain regioregular and stereoregular polyesters, which may have thermal and crystalline properties further ameliorative with respect to non-chiral regioregular polymers.
US11155674B2 Polymerizable sulfonamide compounds and polymers thereof
Methods, compositions, reagents, and systems that allow for the preparation and utilization of sulfonamide salt polymer electrolytes are disclosed herein. Methods and reagents to prepare sulfonamide salt monomers are also disclosed herein. The sulfonamide salt polymer electrolytes can be used as components in energy storage devices, conductive materials, electrochemical cells, gels, adhesives, and drug delivery vehicles.
US11155670B2 Amorphous thermoset thiourethane polymers, method of synthesis thereof and use in bio-electronic devices
An amorphous thermoset thiourethane polymer, comprising a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiourethane linkages, wherein the first type of monomer includes two or more thiol functional groups and the second type of monomer includes two or more isocyanate functional groups. Methods of synthesizing the polymer, bio-electronic devices comprising the polymer and methods of manufacturing such devices are disclosed.
US11155662B2 Improving the properties in PMMA foams by using methacrylic amides
The present invention relates to novel PMMA foams and the production thereof. Here, polymers which have been obtained by copolymerization of methacrylamides such as N-isopropylmethacrylamide and without styrene are foamed. It has surprisingly been possible to establish that a stable, simple-to-produce PMMA foam which has very good properties, e.g. a very high compressive strength, and can be joined more simply to covering layers, especially in comparison with known PMMA foams, can be obtained according to the invention.
US11155658B2 Mixed catalyst systems for producing multimodal elastomers
Embodiments of the present disclosure are directed to multimodal elastomers produced by olefin polymerization with a mixed catalyst system, specifically, a constrained geometry catalyst and a biphenyl phenol catalyst. The multimodal elastomers may be incorporated as impact modifiers in thermoplastic olefins.
US11155656B2 Functional ethylene and 1,3-butadiene copolymer
An ethylene/1,3-butadiene copolymer containing ethylene units, butadiene units and UD units of cyclic, 1,2-cyclohexanediyl structure, and bearing, at one of its chain ends, an alkoxysilyl or silanol function, functional group F1 is provided. The UD units of cyclic structure are of the following formula:
US11155655B2 Organometal catalyst having cationic transition metal complex and borate-based bulky anion, method for preparing the same, and method for preparing oligomer using the same
The present invention provides an organometal catalyst having a cationic transition metal complex and a borate-based bulky anion, a method for preparing the same, and a method for preparing an oligomer using the same.
US11155653B2 Cyclic polyolefins derived from hexyne, octyne, nonyne, pentadecyne and their copolymers with acetylene
Disclosed are saturated cyclic monopolymers derived from hexyne, octyne, nonyne, pentadecyne and saturated cyclic copolymers derived from acetylene and a second alkyne monomer that is hexyne, octyne, nonyne, or pentadecyne.
US11155651B2 Modified vinyl alcohol polymer and method for producing same
An object of the present invention is to provide a modified vinyl alcohol polymer having a sulfonic acid or a salt thereof, the polymer having notably improved water solubility as compared with a pre-modified vinyl alcohol polymer. A modified vinyl alcohol polymer (A) has in a side chain thereof a sulfonic acid group or a salt thereof, and in the modified vinyl alcohol polymer (A), a degree of modification with the sulfonic acid group or the salt thereof is 0.01 mol % or more and 10 mol % or less, and a block character of residual vinyl ester units is 0.55 or more and 1 or less.
US11155647B2 Water-soluble polysaccharide derivatives, process for their preparation, and their uses
A neutral salt consisting of a polyaminosaccharide cation and an anion, as well as a procedure for the preparation of the neutral salt and uses thereof as a biomaterial and as an ingredient in pharmaceutical compositions are disclosed. Indeed, said neutral salt has surprisingly exhibited high water-solubility and high purity, the preparation procedure having minimised the content of high-risk contaminants in the final product and reduced reaction and purification times.
US11155643B2 Glucan kinases and methods for processing starch using the same
Provided herein are a glucan kinase polypeptide, an isolated polynucleotide, and a method for processing starch. The glucan kinase polypeptide comprises an isolated polypeptide including a sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO:22, fragments thereof, variants thereof, and combinations thereof. The isolated polynucleotide comprises a nucleotide sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 21, a fragment thereof, a variant thereof, and a combination thereof. The method for processing starch comprises providing a glucan dikinase; exposing a starch to the glucan dikinase; and collecting the starch that has been exposed to the glucan dikinase.
US11155642B2 Carboxymethyl cellulose and method of preparation
Provided is a method for producing a cellulose derivative. The method includes forming a first reaction product by reacting non-oxidized cellulose with at least one first alkalization agent in the presence of at least one suitable solvent, wherein the first reaction product includes a non-oxidized alkali-cellulose. The method further includes forming a second reaction product by reacting a monohalo-organic compound with a second alkalization agent in a solution, wherein the second reaction product includes a saturated solution and a sediment. The method further includes increasing a temperature of the saturated solution and dissolving at least a portion of the sediment, and reacting the non-oxidized alkali-cellulose with the second reaction product to form an improved carboxymethyl cellulose.
US11155641B2 Cytosol-penetrating antibody and use thereof
The present disclosure relates to a cytosol-penetrating antibody and the use thereof, and more specifically to identification of a structural mechanism that induces escape from endosomes into the cytosol after cellular internalization into living cells through a cell membrane protein, a light-chain variable region and/or heavy-chain variable region, which is based on this identification and has a significantly improved ability to escape from endosomes into the cytosol, a cytosol-penetrating antibody comprising the same, a method for producing the same, and the use thereof.
US11155640B2 Compositions and methods related to engineered Fc constructs
The present invention relates to engineered IgG Fc constructs and uses thereof.
US11155636B2 PRL3 antibody
The present invention relates to humanised antibodies that bind PRL3.
US11155631B2 Macromolecular compositions that cross the blood-brain barrier and methods of use thereof
The invention provides diagnostic and therapeutic macromolecular compositions that cross the blood-brain barrier, in some embodiments in both directions, while allowing their activity to remain substantially intact once across the barrier. Also provided are methods for using such compositions in the diagnosis or treatment of CNS disorders such as Alzheimer's disease.
US11155628B2 Antigen binding proteins that bind c-Met
There is disclosed compositions and methods relating to or derived from anti-c-Met antibodies. More specifically, there is disclosed fully human antibodies that bind c-Met, c-Met-binding fragments and derivatives of such antibodies, and c-Met-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having c-Met related disorders or conditions, including various inflammatory disorders and various cancers.
US11155625B2 Anti-PD-1 antibodies and uses thereof
This disclosure relates to anti-PD-1 (Programmed Cell Death Protein 1) antibodies, antigen-binding fragments, and the uses thereof.
US11155619B2 PD1 and/or LAG3 binders
The present invention provides molecules, such as ISVDs and Nanobodies, that bind to PD1 and LAG3 and, optionally to human serum albumin. These molecules have been engineered so as to reduce the incidence of binding by pre-existing antibodies in the bodies of a subject administered such a molecule. Methods for increasing immune response, treating cancer and/or treating an infectious disease with such molecules are provided.
US11155613B2 Use of anti-FAM19A5 antibodies for treating fibrosis
The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to treat or to diagnose a fibrosis and/or a fibrosis-associated disease in a subject in need thereof.
US11155612B2 vNAR antibody which binds VEGF for use in dogs or cats
The present invention relates to a novel vNAR protein of SEQ ID NO:1 capable of inhibiting the activity of VEGF in carnivorous mammals of the Canis and Felis genera, thereby inhibiting solid tumors growth of both genres.
US11155610B2 Dual PDGF/VEGF antagonists
The invention provides a dual VEGF/PDGF antagonist comprising a VEGF antagonist linked to a PDGF antagonist. The VEGF antagonist is an antibody to a VEGF or VEGFR or is a VEGFR extracellular trap segment (i.e., a segment from the extracellular region of one or more VEGFR receptors that inhibits binding of at least one VEGFR to at least one VEGF). The PDGF antagonist is an antibody to a PDGF or PDGFR or is a PDGFR extracellular trap segment (i.e., segment from the extracellular region of one or more PDGFRs, which inhibits binding of at least one PDGFR and at least one PDGF). The dual antagonist is preferably conjugated to a half-life extending moiety, such as a HEMA-PC polymer. The dual antagonist is particularly useful for treating wet aged related macular degeneration.
US11155606B2 Antibody directed against S. aureus clumping factor a (ClfA)
The present disclosure is directed to a monoclonal antibody, or antigen-binding fragment thereof, that specifically binds to a Staphylococcus aureus clumping factor A protein (ClfA), as well as compositions comprising the monoclonal antibody. The disclosure also is directed to methods of treating a Staphylococcus aureus infection by administering the anti-ClfA monoclonal antibody alone, or in combination with a monoclonal antibody that specifically binds to S. aureus alpha toxin (AT) protein to a subject. Bispecific monoclonal antibodies that specifically bind to both ClfA and AT and methods of using the same also are provided.
US11155599B2 Adenoviruses expressing heterologous tumor-associated antigens
The present invention is directed to adenoviruses for use in cancer therapy which comprise one or more heterologous nucleic acid sequences encoding a tumor antigen, whereby the adenovirus expresses the tumor antigen(s) on its surface.
US11155597B2 Relaxin1 derived peptides for use in immunotherapy
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11155592B2 Protein tyrosine-tyrosine analogs and methods of using the same
PYY analogs are disclosed that include modifications that increase half-life when compared to native, human PYY, as well as additional modifications that increase potency and selectivity to the NPY2 receptor. Pharmaceutical compositions also are disclosed that include one or more of the PYY analogs described herein in a pharmaceutically acceptable carrier. Methods of making and using the PYY analogs also are disclosed, especially for treating obesity and obesity-related diseases and disorders such as type II diabetes mellitus.
US11155591B2 Methods of treating acute pancreatitis using IL-22 fc fusion proteins
The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
US11155589B2 Generation of antigen-specific TCRs
The present invention contemplates methods for the generation of human antigen-specific T lymphocytes. The methods employ MHC class-II targeting signals fused to an antigen or fragment thereof to obtain MHC class presentation of RNA coded proteins. Accordingly, the present invention concerns expression vectors comprising MHC class-II targeting signal and at least one antigen or fragment thereof and its use for the in vitro generation of antigen-specific T lymphocytes. T cell clones and T cell receptors (TCRs) specific for tumor antigens or viral antigens are also described.
US11155585B2 Vaccine against S. suis infection
The present disclosure relates to immunogenic polypeptides, immunogenic compositions and vaccine compositions and use thereof for immunization of mammals susceptible to Streptococcus suis infection. The disclosure also relates to methods for preparing, formulating and administrating such compositions.
US11155581B2 Increasing virus-like particle yield in plants
A method of producing a virus like particle (VLP) in a plant is provided. The method comprises introducing a first nucleic acid and a second nucleic acid into the plant, or portion of the plant. The first nucleic acid comprises a first regulatory region active in the plant and operatively linked to a nucleotide sequence encoding a structural virus protein. The second nucleic acid comprises a second regulatory region active in the plant and operatively linked to a nucleotide sequence encoding a channel protein, for example but not limited to a proton channel protein. The plant or portion of the plant is incubated under conditions that permit the expression of the nucleic acids, thereby producing the VLP.
US11155580B2 Modified proteins and methods of use thereof
This invention is generally related to small proteins, such as miniature proteins, including avian pancreatic polypeptide (aPP), modified so that the small proteins reach the cytosol. In some embodiments, the modified protein molecules deliver an associated cargo molecule to the cytosol. Other embodiments of the invention relate to modified protein fusion molecules that reach the cytosol.
US11155577B2 Thiol-ene based peptide stapling and uses thereof
In one aspect, the invention relates to compositions comprising stapled peptides, methods of making same, pharmaceutical compositions comprising same, and methods of treating various diseases, including, but not limited to, metabolic disorders such as diabetes, and cancers. The disclosed compounds comprise stapled peptides, including, but not limited to, stapled glucagon, axin, and p53 peptide homologues, which are useful as therapeutic agents for a variety of diseases as disclosed herein. The disclosed methods are useful in the preparation of a variety of stapled peptides, including stapled peptide homologues of glucagon, axin, and p53. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US11155574B2 Manufacturing optimization of GL-2045, a multimerizing stradomer
The present disclosure involves optimized methods for production of hiologically active proteins termed optimally manufactured stradomers. The present disclosure further provides compositions and methods useful in the treatment of diseases and conditions including autoimmune diseases, inflammatory diseases, or infectious diseases.
US11155570B2 Methods of preparing steviol glycosides and uses of the same
Methods of preparing steviol glycosides, including Rebaudioside D, Rebaudioside E, Rebaudioside M, Rebaudioside N and Rebaudioside O are provided herein. Sweetener and sweetened consumables containing Rebaudioside D, Rebaudioside E, Rebaudioside M, Rebaudioside N and Rebaudioside O are also provided herein.
US11155569B2 Method of degrading polysaccharide using ozone
The present invention relates to a method for degrading a polysaccharide in the field of food, medicine or chemical industry. In particular, a molecular chain of the polysaccharide is broken by ozone into polysaccharides with smaller molecular weights, oligoses and/or oligosaccharides. The polysaccharides include linear or branched glycans extracted from plants, traditional Chinese medicinal materials, animals, fungi, or microorganisms and sulfated polysaccharides or esterified polysaccharides formed by sulfation or esterification thereof. As an oxidizing agent in the reaction, the ozone can be used alone or can be used under the catalysis of a base, a metal ion, hydrogen peroxide, UV light, or activated carbon to accelerate the reaction. The method for degrading the polysaccharide in the present invention uses milder reaction conditions compared to a conventional acid-catalytic degradation method, has higher reaction efficiency and a controllable reaction process, does not need to use an acid, and reduces environmental pollution.
US11155560B2 Substituted pyrazolo[1,5-a]pyrimidines for modulating CDK9 activity
Inhibitors of CDK9 that are pyrazolo[1,5-a]pyrimidine derivatives and salts thereof, corresponding to formula (I):
US11155559B2 Sulfonyl-substituted isoquinolines as inhibitors of RHO kinase and hERG potassium channel activity
Disclosed are a class of isoquinoline compounds acting as RHO protein kinase inhibitors, and the use thereof in the preparation of a drug for treating diseases associated with RHO protein kinase. Particularly disclosed are compounds as shown in formula (I) and pharmaceutically acceptable salts thereof.
US11155556B2 Pyrimido-diazepinone kinase scaffold compounds and methods for treating PI3K-mediated disorders
The present invention relates to use of pyrimido-diazepinone compounds that are able to modulate protein kinases such as PI3K-γ and PI3K-δ, which are members of the Class I Type IA and Class I Type IB family of phosphatidylinositol-4,5-bisphosphate 3-kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.
US11155554B2 Rigid chiral redox-active isosceles triangular materials
Provided herein are rigid macrocycles comprising a first redox-active subunit and a second redox-active subunit, wherein the first redox-active unit and the second redox-active unit are different subunits. Also provided herein are methods of preparation of the rigid macrocycles and use thereof, for example, in the first of energy generation and storage.
US11155551B2 Nicotinic acetylcholine receptor silent agonists
Derivatives of N,N-diethyl-N′-phenyl-piperazine, a silent agonist of the mammalian α7 nicotinic acetylcholine receptor, are provided. These silent agonists control the desensitization state of the receptor. Further provided are pharmaceutical compositions that allow the administration of the silent agonists of the disclosure to a subject animal or human in need of treatment for a pathological condition arising from such as inflammation. The novel silent agonists also may be co-administered to a patient simultaneously or consecutively with a type II positive allosteric modulator to modulate the activity of the receptor.
US11155546B2 4,6,7-trisubstituted 1,2-dihydropyrrolo[3,4-c]pyridin/pyrimidin-3-one derivatives and uses thereof
The present disclosure relates to 4,6,7-trisubstituted 1,2-dihydropyrrolo[3,4-c]pyridin/pyrimidin-3-one derivatives, and their preparations and medicinal use. Specifically, the present disclosure discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof, wherein the definition of each group is as described in the specification and claims.
US11155545B2 Ribociclib salts and solid state forms thereof
The present disclosure relates to Ribociclib solid state forms, Ribociclib salts including Ribociclib succinate and solid state forms thereof, as well as processes for preparation thereof and pharmaceutical compositions thereof.
US11155543B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same
An embodiment of the present invention provides an organic compound represented by: and an organic light emitting diode and an organic light emitting display device using the organic compound. The organic compound of the present invention includes a phenanthroline core, which has a nitrogen atom of a relatively electron rich sp2 hybrid orbital, and a phosphine oxide moiety, which has an excellent electron transporting property and an excellent thermal stability. The electron transporting property of the organic compound of the present invention is improved based on the chemical structure of the organic compound. Accordingly, when the organic compound is used for the organic light emitting diode and the organic light emitting display device, the driving voltage is reduced, and the lifetime and the emitting efficiency are improved.
US11155539B2 4-pyridinylmethyl-morpholine derivatives and the use thereof as medicament
Disclosed are 4-pyridinylmethyl-morpholines of formula A and pharmaceutically acceptable salts thereof, wherein R1 and R2 are defined herein. Also disclosed are processes for their preparation, pharmaceutical compositions containing the compounds, and their use in therapy, particularly in the treatment or prevention of conditions having an association with NR2B negative allosteric modulating properties.
US11155537B2 Crystal of benzofuran derivative free base and preparation method
This application describes a crystal of a benzofuran derivative free base and a preparation method. Specifically, this application describes crystal A, crystal B, crystal C, and crystal D of N-((4,6-dimethyl-2-carbonyl-1,2-dihydropyridin-3-yl)methyl)-5-ethyl-6-(ethyl(tetrahydro-2H-pyran)4-yl)amino)-2-(piperidin-1-ylmethyl)benzofuran-4-carboxamide and a preparation method for the crystals. The crystals of the compound of formula (I) have great crystal stability and provides improved uses in clinical treatment.
US11155534B2 EGFR inhibitor free base or acid salt polycrystalline form, preparation method therefor, and application
Disclosed are an EGFR inhibitor free base or acid salt polycrystalline form, a preparation method therefor, and an application thereof. The present invention specifically relates to an N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide free base or acid salt polycrystalline form, a preparation method therefor, and an application of the polycrystalline form in preparing a drug for treating an EGFR mutant activity-mediated disease. The present invention is used for inhibiting the activity of an L858R EGFR mutant, a T790M EGFR mutant and an exon 19 deletion activating mutant etc., may be widely applied in preventing and treating cancer, especially non-small cell lung cancer and other related diseases, and is expected to develop into a new generation of EGFR inhibitors.
US11155531B2 N-lipoic-amino acid or peptide, derivatives and their uses
Novel compounds of N-Lipoic-amino acid, N-Lipoic-peptides and their derivatives are described. Also described are compositions and method of compositions containing the derivatives of the amino acids or peptides, and their uses including treating and preventing dermatological or cosmetic conditions or other disorders of the cutaneous system. Compositions and methods of using the compositions for skin lightening and cosmetics are also disclosed.
US11155528B2 Bis-propenamide compounds and methods of treating cancer
A compound of formula (I), wherein R1 is an optionally substituted aryl or an optionally substituted heteroaryl, R2 is an optionally substituted aryl or an optionally substituted heteroaryl, and R3 is an optionally substituted alkylamino, an optionally substituted cycloalkylamino, an optionally substituted arylamino, an optionally substituted heterocyclylamino, an optionally substituted heterocyclyl, and an optionally substituted dialkylamino. A pharmaceutical composition which includes the compound of formula (I) and a pharmaceutically acceptable carrier and/or excipient. A method of treating colorectal cancer in a subject, whereby a therapeutically effective amount of the compound of formula (I) is administered to the subject.
US11155523B2 Biphenyl compound as CCR2/CCR5 receptor antagonist
Provided is a CCR2/CCR5 receptor antagonist and the use thereof in the preparation of a drug for treating diseases associated with the CCR2/CCR5. In particular, disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.
US11155518B2 Peroxyhemiacetal profragrant and proflavor compounds
Provided herein is a compound of Formula I: wherein R represents a terpene hydroperoxyl selected from the group consisting of wherein R′ represents a alkyl group selected from the group consisting: CH3(CH2)8—, CH3(CH2)6—, and CH3—.
US11155517B2 4-substituted phenylamine derivatives and their use to protect crops by fighting undesired phytopathogenic micoorganisms
This invention related to 4-substituted phenylamine derivatives of the general formula (I), wherein R1 to R9 and A have the meanings as defined in description. The invention further relates to methods for their preparation and use of said compounds to fight undesired phytopathogenic microorganisms, and agents for said purpose, comprising said phenylamine derivatives, all according to the invention. This invention further relates to a method for fighting undesired phytopathogenic microorganisms by application of said 4-substituted phenylamine derivatives of general formula (I) to such undesired microorganisms and/or to their habitat, according to the invention.
US11155507B2 Method for producing reaction gas containing (E)-1,2-difluoroethylene
The present disclosure provides a method for producing a reaction gas containing R-1132(E) with selectivity higher than that of known methods. Specifically, the present disclosure provides a method for producing a reaction gas containing (E)-1,2-difluoroethylene (R-1132(E)), (1) the method comprising a step of subjecting a starting material gas containing one or more fluoromethanes selected from the group consisting of chlorodifluoromethane (R-22), difluoromethane (R-32), and fluoromethane (R-41) to a reaction that involves thermal decomposition to obtain the reaction gas, and (2) the starting material gas having a water vapor content of 1 volume % or less.
US11155493B2 Alloy oxide overcoat indium tin oxide coatings, coated glazings, and production methods
The invention provides transparent conductive coatings based on indium tin oxide. The coating has an oxide overcoat, such as an alloy oxide overcoat. In some embodiments, the coating further includes one or more overcoat films comprising silicon nitride, silicon oxynitride, silicon dioxide, or titanium dioxide.
US11155491B2 Multipurpose solution for strengthening and surface modification of glass substrates
Disclosed herein are a composition and one-step method of strengthening glass without heat or chemical processing of the glass itself, while also modifying the surface for improved surface properties. The multifunctional composition is a liquid that can be applied at room temperature and pressure as a topical coating on glass as well as other brittle materials.
US11155485B2 High-purity separation method of iron ions from an aqueous solution containing heavy metal ions
The present invention discloses a high-purity separation method of iron ions from an aqueous solution containing heavy metal ions, wherein after pretreatment of an aqueous solution containing heavy metal ions, sedimentation containing iron ions are collected, nitric acid or sulfuric acid is added for dissolution, and then a reducing agent is added to the dissolved solution; and after heating and sealing reaction, red sedimentation is generated at the bottom, The sedimentation has a high purity, and the residual amount of iron in the solution is less than 0.4 mg/L. In the method, iron ions in the solution can be converted to hematite crystals at a high purity, and the solution has an excellent retention rate of heavy metal ions, the reaction time is short, the separation efficiency is high, the operation is simple, and the cost is low.
US11155482B2 Apparatus and method for aerating wastewater
An aeration apparatus including a tank defining a cavity to receive a liquid, at least one aerator positioned within the tank, and a plenum connected to a bottom surface of the tank and in fluid communication with the at least one aerator, in which an air flow is directed from the plenum into the at least one aerator to deliver air to the liquid in the tank to oxidize the fluid.
US11155479B2 Methods and compositions for removing contaminants from wastewater streams
A chemically modified polysaccharide additive may be introduced to a wastewater stream in an effective amount to remove oil-coated particulates and/or heavy metal contaminants from the wastewater stream. The chemically modified polysaccharide includes at least one sulfur-containing moiety and/or nitrogen-containing moiety and the contaminants may be removed by using this chemically modified polysaccharide to capture the contaminants and separating out the captured contaminants.
US11155478B2 Method for improving overflow clarity in production of coal
A transitional treatment composition and methods of treating coal refuse are provided. The transitional treatment composition comprises an anionic acrylate-acrylamide copolymer having from about 30 mole percent to about 50 mole percent (meth)acrylate, from about 50 mole percent to about 70 mole percent (meth)acrylamide, and a reduced specific viscosity of from about 18 dL/g to about 30 dL/g. The transitional treatment composition can be made down in an aqueous liquid.
US11155472B2 One-dimensional nano-chain structure and preparing method thereof
The present disclosure relates to a one-dimensional nano-chain structure including a single crystal structure as a minimum repeat unit structure.
US11155469B2 Mesoporous composite comprising anhydrous, amorphous magnesium carbonate and calcium carbonate, and methods of production thereof
An X-ray amorphous magnesium carbonate is disclosed that is characterized by a cumulative pore volume of pores with a diameter smaller than 10 nm of at least 0.018 cm3/g, and a specific surface areas of at least 60 m2/g. The X-ray amorphous magnesium carbonate is produced by reacting an inorganic magnesium compound with alcohol in a CO2 atmosphere. The X-ray amorphous magnesium carbonate can be a powder or a pellet and acts as a desiccant in, for example, production of food, chemicals or pharmaceuticals.
US11155467B2 Solidothermal synthesis of a boron-containing zeolite with an MWW framework structure
Described herein is a process for producing a zeolitic material having an MWW framework structure containing YO2 and B2O3, in which Y stands for a tetravalent element. The process includes the steps of (i) preparing a mixture containing one or more sources for YO2, one or more sources for B2O3, one or more organotemplates, and seed crystals, (ii) crystallizing the mixture obtained in (i) for obtaining a layered precursor of the MWW framework structure, and (iii) calcining the layered precursor obtained in (ii) for obtaining the zeolitic material having an MWW framework structure. Also disclosed herein are synthetic boron-containing zeolites obtain by the process and uses thereof.
US11155466B2 Method for preparing graphite sheet
The embodiment relates to a method for preparing a graphite sheet having a high thermal conductivity at a low cost without using an expensive polyimide film.
US11155464B2 Method for producing hydrogen fluoride from its aqueous solutions
Extraction of anhydrous hydrogen fluoride from its aqueous solution is provided. A method provides hydrogen fluoride from aqueous solutions, including the reduction of water component of the aqueous solution at an elevated temperature into carbon oxide, carbon dioxide and hydrogen. The condensation and distillation of the obtained hydrogen fluoride and water vapor are characterized by the fact that the mixture of hydrogen fluoride and water is reduced at a temperature of 800 K and above, the molar ratio of carbon to water in the reducing agent is from 0.5 to 4, and using a reducing agent of the general formula CnHmOk, where k≥0, m>0, and n>0, and the reducing agent may be saturated, unsaturated, aromatic hydrocarbons, oxygen-containing organic compounds, their isomers and their mixtures. The method makes it possible to extract hydrogen fluoride from its mixtures with water in any ratio and from azeotropic mixtures.
US11155461B2 Atomically-precise products and methods and systems for manufacturing the same
Systems, methods, and tools for the synthesis of atomically-precise products via mechanosynthesis are disclosed, including a set of atomically-precise tips and associated reactions, methods for determining build sequences for workpieces, exemplary build sequences, and methods for creating new reactions, build sequences, and tips.
US11155456B2 Intelligent loading for an agricultural machine
An intelligent, automated system for loading agricultural product application equipment is provided in which a control system can determine a necessary amount of product for completing a field operation and can automatically couple with a tendering system to receive such product at an optimal time and location. The control system can determine a current amount of product, a projected amount of product necessary to complete a field operation and a refill amount of product from the current amount and the projected amount, then transmit the refill amount to the tender. The control system can further determine whether a position of the equipment relative to the tender is within a threshold, and whether an intake coupler of the equipment is connected to a supply coupler of the tender, and can control valve(s) to open and close channel(s) for loading fluid into the storage tank.
US11155453B2 Container filling assembly
A container filling assembly that can be used with container filling systems to fill containers during successive filling cycles with the same or different fluid compositions at high rates of speed, with little to no machinery changeover, and/or with little to no fluid waste.
US11155450B2 Vehicle, winch for vehicle and warning control device for winch of vehicle
The present disclosure discloses a vehicle, a winch for the vehicle, and a warning control device for the winch of the vehicle. The warning control device includes: a warning component; and a warning control board, including: a load detector, connected to the motor through a current sensor, and configured to detect load condition of the motor by collecting measured working current of the motor; a processor, connected to the load detector and the warning controller respectively, and configured to output a warning control signal to the warning controller according to the load condition of the motor; and a warning controller, connected to the warning component and the processor respectively, and configured to receive the warning control signal and to control the warning component to produce a warning based on the warning control signal.
US11155443B2 Method for forming a tubular construction element
A tubular construction element and a method for forming a tubular construction element built of longitudinally extending segments in which the segments are joined together in a side-by-side relationship and in which the longitudinal direction of the tubular construction element being greater than the diameter thereof.
US11155438B2 Diagnostics solution for elevators
The invention relates to a solution for diagnosing an operational condition of at least one device of an elevator car. The solution comprises the at least one device, an image capturing device, at least one reflective surface arranged to a position in an elevator car forming a path of reflection between the image capturing device and a portion of the at least one device, and a control device, In the solution the at least one device is caused to set the operating state and the image capturing device is configured to capture an image at least on the portion of the at least one device seen by the image capturing device through the at least one reflective surface, the image data is analyzed and based on that the operational condition of the device is concluded.
US11155435B2 Dispenser
A sheet dispenser system having a roll of sheet material and a housing to receive the roll. The roll of sheet material comprises a first end portion incorporating a key, and the housing comprises a mounting portion arranged to support the first end portion of the roll. The mounting portion comprises a lock arrangement which is movable between a locked condition and a free condition. The lock arrangement comprises a rotatable element configured for rotation about an axis, and a locking element configured for engagement with the rotatable element to inhibit rotation of the rotatable element, such that, when the locking element and the rotatable element are engaged, the lock arrangement occupies the locked condition, and when the locking element and the rotatable element are disengaged, the lock arrangement occupies the free condition. The mounting portion is arranged such that the roll is movable between an engaged condition, in which the key engages the mounting portion, and a disengaged condition, in which the key is disengaged from the mounting portion, such that, when the roll is moved from the disengaged to the engaged condition, the first end portion of the roll moves the lock arrangement into the free condition, thereby permitting rotation of the rotatable element. The locking element and the rotatable element are configured for engagement by relative movement of the locking element and the rotatable element towards each other in a direction along the axis of rotation of the rotatable element.
US11155433B2 Tape machine
A tape machine includes a base, one or more wheels connected to the base, one or more uprights extending upwards from the base, a roller connected to the base, and a tape roll housing connected to the uprights and configured to receive a roll of tape therein to allow for rotational unwinding of the roll of tape. A cutter connected to the base and moveable between an idle position and a cut position. A blade on the cutter is moveable to cut the tape when in cut position.
US11155428B2 Material and hardware to automatically clean flexible electronic web rolls
Novel materials and devices can remove small defects from long rolls of flexible electronics material while they are in continuous motion. The cleaning materials are designed to remove small particles without transferring defects or damaging the flexible electronics. The device generally consists of variable speed, motor-driven cylinders mounted on moveable brackets. The cylinders are capable of matching the speed of the cleaning material such that the cleaning material is always in contact with the web roll to be cleaned. The brackets are capable of rotating so the same material can be used more than once. Another material is used to remove debris from the cleaning material. A similar device consisting of motor-driven cylinders and moveable is used to apply the debris removal film to the cleaning film, allowing the cleaning film to be used multiple times.
US11155427B2 Device for the surface treatment of a substrate, comprising a metallic conveyor belt
A device for the surface treatment of a substrate including a transport device, a vacuum suction device, a corona device and a coating device, is described. The transport device is formed as a conveyor belt. The conveyor belt is formed as a vacuum suction belt of the vacuum suction device, and the conveyor belt is formed as a counter electrode of the corona device.
US11155422B2 Product transfer device
The present invention relates to a method for transferring products (1) between a main conveyor (2) which is configured to convey products in a longitudinal direction and an accumulation surface (3) using an intermediate conveyor (4) and a pushing means (5). The method comprises acceleration of the intermediate conveyor (4) and transfer of products (1) between the intermediate conveyor (4) and the main conveyor (2) via the action of the pushing means (5), and deceleration of the intermediate conveyor (4) and transfer of products (1) between the intermediate conveyor (4) and the accumulation surface (3). The present invention also relates to a device for transferring products (1) between a main conveyor (2) which is configured to convey products in a longitudinal direction and an accumulation surface (3), enabling in particular the method according to the invention to be carried out.
US11155416B2 Conveyor belt monitoring system and method
A conveyor belt monitoring system may utilize one or more ultrasonic sensors to identify variations in the position of the conveyor belt. These variations may be minor variations in belt position, which can be identified by the belt monitoring system well before they would be readily perceptible by a user. The monitoring system may be operated in conjunction with one or more belt adjustment mechanisms which can be used to correct the path of the conveyor belt based on information gathered by the monitoring system.
US11155415B1 Belt clip set, rod belt, and method for affixing the belt clip set on a rod belt
The present disclosure relates to a belt clip set comprising a belt clip and at least two pilot bolts, the belt clip comprising a first leg having at least two guide openings and a second leg having at least two thread openings each associated with the guide openings. Each pilot bolt comprising a threaded region with an external thread, a bolt head for tightening the pilot bolt, and a tapered pin opposite the bolt head, where each pilot bolt can be received with some play in one of the guide openings in the first leg and via its threaded region screwed into the respective associated thread opening in the second leg, where each pilot bolt can be received with some play in one of the guide openings in the first leg and via its threaded region screwed into the respective associated thread opening in the second leg.
US11155413B2 Modular spiral chute
A spiral chute having a center column assembly with a first center column segment is disclosed. The center column segment has a plurality of pairs of opposed apertures. The spiral chute also includes a plurality of chute assembly sections, each including a chute support arm, a chute section coupled to the chute support arm, an outer wall support coupled to a distal end of the chute support arms, an outer wall segment coupled to the outer wall supports, and a support arm bolt having a distal end and a proximal end. The distal end of each support arm bolt passes through a corresponding one of the first plurality of opposing apertures and engages a proximal end of the chute support arm such that the proximal end of the chute support arm abuts the first center column segment. A method of constructing a spiral chute is also disclosed.
US11155410B2 Automatic locker device with at least one buffer zone for the loading/recovery of loads and corresponding method for handling loads
An automatic locker device is configured for handling loads with operations of loading and retrieval. The device includes at least one storage zone for storing loads, at least one retrieval point and a handling mechanism, which is configured to move the loads from the at least one storage zone to the at least one retrieval point, for the retrieval operations. The automatic locker device also includes at least one buffer zone, distinct from the at least one storage zone. The handling mechanism is configured to move the loads from the at least one buffer zone to the at least one storage zone, for the loading operations.
US11155405B2 Waste disposal apparatus
A waste disposal apparatus, such as a waste disposal container or unit that is configured to receive used personal care products in a discreet and sanitary manner. Instances of incontinence, menstruation or uncontrollable bodily functions can be a personal situation that is otherwise unknown to others. However, current receptacles available to dispose of used personal care products fail to provide for a hygienic, easily accessible and discreet that is designed for small spaces, such as a home bathroom or public restroom stall.
US11155400B2 Pill-dispensing package
A pill-dispensing package includes a container and a closure. The container is formed to include an interior product-storage region to store pills therein. The closure is coupled to a filler neck of the container.
US11155399B2 Dual-pump outflowing liquid container
The present disclosure provides a dual-pump outflowing liquid container, comprising an outer tube, an inner tube and a pump core mechanism, wherein the pump core mechanism includes a pump core mounting seat, the first vacuum pump, the second vacuum pump and a pressing head, the embedding connector is connected to the inner tube embedding mounting hole in a sealing manner, the pump core mounting seat is detachably connected to the top end of the outer tube, the first pump core mounting hole corresponds to the first pump core intercommunication hole, the second pump core mounting hole corresponds to the second pump core intercommunication hole, the pressing head is slidably connected to the pump core mounting seat, a passage inlet of the first outflowing liquid passage is abutting with a pump outlet of the first vacuum pump in a sealing manner.
US11155396B2 Multipurpose inflatable package
A precursor for an inflated package comprises an article-receiving pocket for insertion of the article into the pocket. Inflatable panels connected around the article receiving pocket are foldably connected to the article receiving pocket. The precursor is inflated and the article is placed therein before or after inflation. The inflated package is then placed in a box. The panels cushion the pocket part from the sides, wall and floor of the box.
US11155385B2 Container holder
A container holder including a body portion having a first end, a second end, an inner surface, and an outer surface, wherein an interior region of the body portion is defined as a generally axial opening between the first end and the second end, and at least one retaining element disposed along the inner surface of the body portion, wherein a container is received within the generally axially opening of the body portion, and the at least one retaining element exerts a force against the container to retain the container within the generally axial opening. Furthermore, an associated method is also provided.
US11155381B1 Joinable thermoform product packaging
A package for a product that contains a first and a second thermoform container body that are configured to support the product. The first container body includes a first outer wall extending along a side of the first container body and defining a first mating surface and a first interlocking structure proximate the first outer wall and including an outer surface. The second container body includes a second outer wall extending along a side of the second container body, an inner wall disposed inwardly of the second outer wall and defining a second mating surface, and a second interlocking structure intermediate the second outer wall and the inner wall. The first and second interlocking structures are configured to interlock with one another when the outer surface of the first interlocking structure is placed in facing engagement with the inner surface of the second interlocking structure.
US11155380B2 Dispenser bag container and dispenser rack
A bag container dispenser includes a bag container. The container is formed of resilient material and has a bottom, a top, first and second sides, a front, a back and a removable access panel. The access panel has a top segment that includes a portion of the top and a connected front segment. The front segment has a height that extends from the bottom to the top. Stacked bags are sized and shaped to fit within the bag container. Each of the bags has a front wall, a back wall, an open top and a closure mechanism. The bags are dispensable from the container through an opening provided by removal of the access panel which may have a removable cover. A dispenser rack has a horizontal platform sized and shaped to support the bag container. Peripheral guards extend upward from the platform and constrain movement of the container during dispensing.
US11155378B2 Gating system for accumulating items and related filling machine and methods
A filling machine for filling a receptacle with a plurality of items includes a first item drop path having an outlet end, a second item drop path having an outlet end, the second item drop path distinct from the first item drop path and a gating system for selectively accumulating and releasing items. The gating system includes: a single gate mechanism configured for selectively and independently controlling both (i) whether items can exit the outlet end of the first item drop path and (ii) whether items can exit the outlet end of the second item drop path.
US11155374B2 Method of forming multi-compartment tobacco pouch
Methods of forming a tobacco pouch having two or more compartments are disclosed. The methods include forming a multi-compartment tobacco pouch with a vertical form fill seal machine.
US11155373B2 Headspace modification method for removal of vacuum pressure and apparatus therefor
To modify the headspace in a container to remove vacuum pressure, a container has a seal or cap which may provide a temporary opening into the container which is sealable under compression to provide a controlled raising of the internal pressure as the heated contents of the container cools. A sealing chamber (84) may enable the introduction of a fluid into the headspace (23b) to force the fluid level (40) lower. Other methods and apparatus are described.
US11155372B2 Tray sealing machine and method for gently picking up a tray
The present disclosure relates to a tray sealing machine and, in addition, to a method for gently picking-up trays and for gently depositing sealed packages.
US11155371B2 Device for the dosed filling of a container with a filling material
A device for the dosed filling of a container with a filling material has a holding unit for holding the container and a filling unit by which a defined amount of filling material is withdrawn from a material store and transferred into the container. The filling unit has a dosing chamber. The dosing chamber is mounted displaceably alternately between a first position and in a second position. In its first position, the dosing chamber is in contact with the material store so that filling material can be transferred out of the material store into the dosing chamber. In its second position, the dosing chamber is situated above the container so that the filling material in the dosing chamber can be emptied into the container. The material store is in the form of a separate container and can be fastened detachably to the device by a fastening unit.
US11155369B2 Artificial satellite and method of controlling the same
Provided are an artificial satellite and a method of controlling the same. The artificial satellite includes a main body flying along an orbit of a planet, an optical payload arranged on the main body to photograph a ground surface of the planet, and a pair of solar cell panels rotatably arranged on both sides of the main body in a first direction, wherein the first direction and a flight direction of the main body form an acute angle with each other.
US11155368B1 Multiple thruster firing on a single articulable module
A spacecraft includes a propulsion subsystem including at least two electric thrusters, an electrical interface assembly that couples electrical conductors from the thrusters to a spacecraft harness, a pneumatic interface assembly that controls flow rate of propellant to the thrusters and a thruster support module (TSM) including a pointing arrangement and a mounting arrangement. A proximal portion of the mounting arrangement is coupled with a distal portion of the pointing arrangement; the at least two electric thrusters are disposed on a distal portion of the mounting arrangement; the electrical interface assembly and the pneumatic interface assembly are disposed on the proximal portion of the mounting arrangement. The mounting arrangement is configured to limit heat transfer between the thrusters and (b) one or more of the proximal portion of the mounting arrangement, the electrical interface assembly and the pneumatic interface assembly.
US11155367B2 Single-axis pointing pure magnetic control algorithm for spacecraft based on geometrical analysis
Provided is a single-axis pointing pure magnetic control algorithm for a spacecraft based on geometrical analysis to realize single-axis pointing control of the spacecraft through the pure magnetic control algorithm in which a magnetic torque is only output by a magnetorquer to interact with a geomagnetic field to generate a control torque. The algorithm uses a spatial geometry method to obtain an optimally controlled magnetic torque direction, thereby designing a PD controller. The problem that the traditional magnetic control method is low in efficiency and even cannot be controlled is overcome. The algorithm is simple and easy, can be used in the attitude control field of spacecrafts, and achieves the pointing control in point-to-sun of a solar array and point-to-ground of antennae.
US11155366B2 Interlocking, reconfigurable, reconstitutable, reformable cell-based system with nested ring structures
Cell-based space systems with nested-ring structures that interlock and can change configuration to support a mission are provided. The cells may self-assemble into a larger structure to carry out a mission. Multiple rotatable rings may be included in a cell, with a payload/control section in the center. The rings may provide power and/or data to trams that move about the rails. Trams may interlock with other cells, carry sensors or other devices, etc. Cells may be stowed in a cell stack that is deployable. Such cell-based systems may have various applications in space, on Earth, other celestial bodies, and underwater.
US11155362B2 Hybrid air transportation
Provided is a transportation system comprising (a) a ground-based powered tug vehicle, (b) an airborne vehicle, and (c) a towline with end links connecting the ground-based vehicle and the airborne vehicle. Also provided are methods of transportation utilizing the transportation system.Additionally provided is a transportation system comprising a hybrid vehicle that is propelled on a highway by a linear induction electric motor comprising a stationary motor element (“stator”) and a moving motor element (“rotor”), where the stator is incorporated into a groove in the highway and the rotor is incorporated into the hybrid vehicle and protrudes into the groove in the highway; and where the hybrid vehicle further comprises at least one wing that elevates the hybrid vehicle when propelled to a take-off speed on the highway. Methods of transportation utilizing this hybrid vehicle transportation system are further provided.
US11155360B2 Method for monitoring aircraft engines
A method for monitoring at least one engine of an aircraft wherein the aircraft includes a passenger cabin. The method includes a step of acquiring a signal that is at least in part representative of the activity of the engine, using a sensor during a flight of the aircraft, and searching for a defect in the engine by a processing unit using data obtained from the signal. In some embodiments, the sensor is in a mobile device located in the passenger cabin. In some embodiments, the health of the at least one engine uses the signal acquired by a plurality of mobile devices.
US11155359B2 Aircraft fuel tank pressurization systems and methods
Systems and methods are provided for storage in at least one on-board fuel tank of aircraft fuel under a predetermined pressure and at an internal ambient tank temperature. A passive heat exchanger having an exchanger inlet is fluid-connected to a propulsion engine of the aircraft to receive heated pressurized bleed air therefrom while an exchanger outlet is fluid connected to the fuel tank. The passive heat exchanger is configured to cool the heated pressurized bleed air from the engine by heat transfer to a surrounding environment by radiation and convection so as to supply pressurization air to the fuel tank at the predetermined internal tank pressure and the internal ambient tank temperature. A system controller is provided to provide the fuel tank with pressurized air at a predetermined temperature during various aircraft flight phases.
US11155356B2 Thrust allocation using optimization in a distributed flight control system
Thrust values for motors in an aircraft are generated where each flight controller in a plurality of flight controllers generates a thrust value for each motor in a plurality of motors using an optimization problem with a single solution. Each flight controller in the plurality of flight controllers passes one of the generated thrust values to a corresponding motor in the plurality of motors, where other generated thrust values for that flight controller terminate at that flight controller. The plurality of motors perform the passed thrust values.
US11155355B2 Mounting assembly
A mounting assembly for coupling an accessory to a frame including a base configured to be coupled to the frame; the base having a hollow portion; the hollow portion including a receiving end including a tapered socket; an internal interlocking portion adjacent to the tapered socket; and a securing end opposite from the receiving end; a shaft configured to be connected to an accessory at a first end and received in the hollow portion of the base in an engaged position, the shaft including a tapered boss adjacent to the first end, the tapered boss configured to engage the tapered socket; an external interlocking portion adjacent to the tapered boss configured to engage the internal interlocking portion; and a second end opposite from the first end, the second end including a threaded surface; wherein when the shaft is in an engaged position, the shaft is static in the hollow portion.
US11155352B2 Aircraft mounted hoist system having a multi-stranded wire rope cable
A hoist system includes a wire rope cable having a first end and a second end. The wire rope cable further including multiple strands twisted into a helical shape. The hoist system further including a lifting mechanism configured to attach to the first end of the wire rope cable. The lifting mechanism including at least one of a rotating drum and a set of frictional rollers. The hoist system further including a motor configured to rotate the lifting mechanism; and a housing configured to house the lifting mechanism, the motor, and at least part of the wire rope cable.
US11155347B2 Rotorcraft blade grip
An embodiment rotorcraft main rotor system, including a yoke, a rotor blade, and a grip assembly attaching the rotor blade to the yoke. The grip assembly includes a grip body formed from a contiguous laminated composite and has a substantially constant thickness, where the grip body has an upper extension, a lower extension and a connecting portion connected between an inboard end of the upper extension and an inboard end of the lower extension. An inside surface of the upper extension faces, and is substantially parallel to, an inside surface of the lower extension, and the upper extension has first features and the lower extension has second features that are aligned with the first features, where the first features and second features each include at least one of an edge contour, attachment holes, or first protective elements.
US11155338B2 Encryption and security in a distributed control network
Methods and systems are provided for controlling a component of an aircraft engine by communicating data over an inner control loop portion of a distributed engine control network for an aircraft; and controlling an operation of the aircraft engine by communicating encrypted data over an outer control loop portion of the distributed engine control network, wherein the data communicated over the inner control loop portion is unencrypted or encrypted with weaker encryption than the data communicated over the outer control loop portion.
US11155334B2 Fan blade support assembly
A fan blade support assembly for an aircraft is generally disclosed. The fan blade support assembly includes a fan assembly having a plurality of fan blades, a power shaft extending between the fan assembly and an engine of the aircraft, and a housing assembly positioned around the power shaft. The housing assembly includes a convergent housing and a sealing shroud. The convergent housing includes a cap, a base, and a middle portion extending therebetween. The base defines a first diameter, and the cap defines a second diameter less than the first diameter. The sealing shroud is positioned between the convergent housing and the power shaft. A gap is defined between the sealing shroud and the power shaft.
US11155330B2 Foldable wing extensions for aircraft
A propulsion and lift system for an aircraft includes a wing having an outboard end and a pylon assembly coupled to the outboard end of the wing. The propulsion and lift system also includes a wing extension rotatably coupled to the outboard end of the pylon assembly. The wing extension is rotatable between a flight position in a flight mode and a stow position in a storage mode. The wing extension folds inboard in the stow position, thereby reducing a wingspan of the aircraft in the storage mode.
US11155328B1 Air vehicle with a controlled buoyancy lifting system and method thereof
An air vehicle comprises a payload vessel, a propulsion system, and a buoyancy lifting unit anchored on said payload vessel. The buoyancy lifting unit comprises a plurality of balloons and a plurality of buoyancy gas reservoirs arranged in horizontal rows and vertical columns, a protractible rod, and a control system. Each of the balloons and buoyancy gas reservoirs is tethered to a lifting-joint on the protractible rod through a cable. The control system controls vertical move of the air vehicle to ascend through directing buoyancy gas flow from the buoyancy gas reservoirs into the balloons, and to descend through directing buoyancy gas flow from the balloons into the buoyancy gas reservoirs. The propulsion system controls horizontal move of the air vehicle to go forward and make turns.
US11155327B1 Trolling motor and foot pedal for trolling motor
A trolling motor has a steering motor transmitting torque to a steering shaft, which is coupled to a lower propulsion unit such that rotation of the steering shaft rotates the propulsion unit about a steering axis. A controller is in signal communication with the steering motor. A foot pedal in signal communication with the controller has a foot pad pivotable about a pivot axis and sends electrical steering signals to the controller (and thus steering motor) in response to pivoting of the foot pad. A variable resistance device is coupled to the foot pedal and controllable to vary resistance to pivoting of the foot pad about the pivot axis based on a position, velocity, acceleration, and/or jerk of the steering shaft. Additionally or alternatively, the variable resistance device provides haptic feedback to a user via the foot pad to inform the user about information related to the trolling motor system.
US11155326B2 Bio-inspired underwater robot
A bionic underwater robot for achieving a variety of motions is disclosed. The bionic underwater robot includes a head and one or more tail structures. Each of the one or more tail structures includes one or more joint structures. Each of the one or more joint structures includes a connection plate, and a modular assembly, comprising an upper servo motor, a lower servo motor, and a bevel gear mechanism, is motorized for performing various movement motions of the joint structure. The bevel gear mechanism is integrally formed by an intermediate bevel gear, a first bevel gear, and a second bevel gear. The upper servo motor drives the first bevel gear from a first side of the modular assembly, while the lower servo motor drives the second bevel gear from a second side.
US11155324B2 Methods and systems for wave slam monitoring of water vessels
A method of monitoring wave slam on a vessel includes measuring acceleration forces from mechanical shocks on the vessel using one or more sensors communicatively coupled to a computing unit. Generating real-time acceleration information representative of the wave slam based at least in part on the data obtained from the sensors. Generating acceleration prediction information representative of a predicted wave slam based at least in part on the generated real-time acceleration information. Presenting at least one of the generated real-time acceleration information or acceleration prediction information to an intended recipient.
US11155318B2 Device for selective rotation of vehicular handlebar
Apparatus is for, or is included with, a vehicle having a vehicular handlebar, and also having first and second pipe portions. The first elongated portion is configured to receive and support a vehicular handlebar, and to be slidably received, at least in part, in the second elongated portion. An engagement device is configured to selectively engage the first and second pipe portions with each other. The engagement device, in use, prevents the first and second pipe portions from rotating relative to each other. The engagement device is also configured to selectively disengage the first and second pipe portions from each other. The engagement device, in use, permits the first and second pipe portions to rotate relative to each other. A clamp assembly is configured to selectively clamp the first elongated portion and the second elongated portion with each other.
US11155317B2 Bike frame
A bike frame includes including a seat tube (10) for receiving a seatpost (2), a front portion comprising a top tube (13) connecting the seat tube (10) to a head tube (16), the seat tube (10), the top tube (13). The head tube (16) extends in a plane of symmetry of the bike frame (1). A rear portion has two chain stays (11a, 11b) and two seat stays (12a, 12b) arranged symmetrically relative to the plane of symmetry of the bike frame (1). The two seat stays (12a, 12b) are independent of each other and the two seat stays (12a, 12b) have a preform that is curved along at least one arc in a plane passing through the two seat stays, so as to enable the two seat stays to move away from or closer to each other under the action of a vertical load.
US11155316B2 Saddle-type vehicle
This saddle-type vehicle includes an occupant protection device (21), a plurality of acceleration sensors (S1 and S2) which detect translational acceleration in a forward and backward direction acting on a vehicle, and a control device (25) which controls an operation of the occupant protection device (21) on the basis of detection values of the acceleration sensors (S1 and S2). The plurality of acceleration sensors (S1 and S2) include a first acceleration sensor (S1) and a second acceleration sensor (S2). The first acceleration sensor (S1) is disposed above a center of gravity (G) of the vehicle. The second acceleration sensor (S2) is disposed below the center of gravity (G). The control device (25) averages a detection value (de1) detected by the first acceleration sensor (S1) and a detection value (de2) detected by the second acceleration sensor (S2) and controls an operation of the occupant protection device (21) on the basis of the averaged value.
US11155315B1 Bicycle frame lighting system
A bicycle frame lighting system comprising a top light assembly and a bottom light assembly. The top light assembly is assembled to left and right sides of a top tube of a bicycle, wherein the top light assembly includes a pair of top light assembly components that can be detached and re-attached such that top tube is secured between a cavity formed between the top light assembly components. The bottom light assembly is assembled to left and right sides of a bottom tube of the bicycle, wherein the bottom light assembly includes a pair of bottom light assembly components that can be detached and re-attached such that bottom tube is secured between a cavity formed between the bottom light assembly components. The bicycle frame lighting system further comprises a battery housing holding a power source for powering the top light assembly and the bottom light assembly.
US11155314B1 Virtual stop station
A virtual stop station is provided having a carriage straddling an assembly line operation. This provides an independently moving platform upon which one or more manufacturing robots are affixed. The carriage is coordinated with and tracked to the linear motion of the assembly line. A vision guidance system centers the workpiece, and lifting arms mounted on the moving carriage will locate the workpiece and lift the workpiece up off of the conveyor, while being coordinated with it. The workpiece and robots thus are now fixtured to the same frame, thus eliminating movement relative to one another creating a virtual stop station. Once subassembly is complete, the coordinated robotic gantry will disengage from the conveyor and return home. The instant abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
US11155311B2 Vehicle aerodynamic improvement apparatus and system
System and apparatus for improving aerodynamics of a vehicle including: a plurality of stiffeners offset from each other; a first airfoil configured as a thin-form sheet; a second airfoil coupled to the first airfoil using the plurality of stiffeners, wherein a trailing edge of the first airfoil overlaps a leading edge of the second airfoil; an airflow inlet defined by a leading edge of the first airfoil and a pair of stiffeners of the plurality of stiffeners; and an airflow outlet defined by the trailing edge of the first airfoil, the leading edge of the second airfoil, and the pair of stiffeners.
US11155306B2 Vehicle side outer structure
A vehicle side outer structure includes a master side outer panel having a front door opening and a rear door opening, and a quarter garnish panel joined to a rear edge of the master side outer panel, wherein the quarter garnish panel is configured to be changeable in response to a partial design change of a vehicle.
US11155304B2 Utility vehicle
A utility vehicle includes a vehicle body frame, a pair of right and left front wheels disposed at a front end of the vehicle body frame, and a pair of right and left rear wheels disposed at a rear end of the vehicle body frame. The vehicle body frame has, at a bottom thereof, a bottom main frame extending in an anteroposterior direction at a center in a vehicle width direction, and a pair of right and left bottom side frames located width direction extending in the anteroposterior direction between the front wheels and the rear wheels at outer ends in the vehicle, and the bottom side frames are located above the bottom main frame.
US11155302B1 Dynamically balanced in-line wheel vehicle
A family of vehicles is presented which exploit dynamic controls to stabilize in-line two wheeled vehicles. The stabilization results in improved safety at high speeds and on uncooperative surfaces. Stabilization affords balance at zero speed without auxiliary support means. Transformational wheel base length affords high visibility at low speeds and low drag at high speeds. In wheel chair configurations transforming wheel base length allows navigation up and down stairs.
US11155298B2 Modified steering angle at completion of hitch assist operation
A vehicle maneuvering apparatus comprises a steering control system configured to control a steering angle of a plurality of steered wheels of a vehicle. The controller is further configured to control the vehicle to stop in a stopped position upon completing a vehicle alignment routine and identify an alignment error distance between the hitch and the coupler position in the stopped position. The controller is further configured to calculate a change distance of the hitch based on the steering angle and calculate an aligned steering error distance. The aligned steering error distance is calculated by comparing the change distance to the alignment error. Based on the aligned steering error distance, the controller may selectively suppress the steering angle alignment routine.
US11155296B2 Systems and methods for correcting steering offsets
A system for correcting a steering offset generated by an active steering system of a vehicle includes a vehicle comprising a pair of steered road wheels. The system also includes a controller configured to direct a change to an angle of the steered road wheels when a determined steering state of the vehicle is a steering slowly state.
US11155295B2 Hydraulic steering unit
A hydraulic steering unit includes a pressure port connected to a main flow path and a tank port connected to a tank flow path, left and right working ports connected to left and right working flow paths, respectively, a bridge arrangement of variable orifices having a first left orifice connected to the main flow path and to the left working flow path, a first right orifice connected to the main flow path and to the right working flow path, a second left orifice connected to the left working flow path and to the tank flow path, and a second right orifice connected to the right working flow path and to the tank flow path. A variable diagonal orifice is connected to the main flow path and to the tank flow path. The bridge arrangement orifices being closed in neutral position and the diagonal orifice being open in neutral position.
US11155283B2 Insert and wear ring for a railway roller bearing
In accordance with one aspect of the present disclosure, a wear ring assembly is provided for a railway roller bearing. The wear ring assembly includes a wear ring having a central opening for receiving a journal of a railway wheel assembly and an insert including a plurality of spacers configured to extend in the opening of the wear ring to separate the wear ring from the journal. The spacers are spaced apart from each other about the wear ring. The insert may include one or more flanges that separate the wear ring from a bearing cone.
US11155281B2 Vehicle guidance system
Vehicle guidance system that includes a first guidance bogie selectively positionable in a first position for travel and a second position for direction change and a second guidance bogie selectively positionable in a third position for travel and a fourth position for direction change. At a common crossing, one of: the first guidance bogie is selectively positioned into the second position, or the second guidance bogie is selectively positioned into the fourth position.
US11155280B2 Freight car truck bolster
A novel freight car truck bolster comprising a top member with a center bowl and support shelves for side bearers, a bottom member with bearing surfaces for swing suspension springing elements, going into diagonal tension members, side walls joining the top and bottom members, vertical longitudinal ribs located between the top and bottom members with their thickness increased in the center bowl area, pockets to install friction wedges. The bottom member has increased thickness in the transition areas of the bearing surfaces into the diagonal tension members, and the vertical ribs have thickness increased at the top of the center bowl area, the rounded transitions of the sloping walls into the bottom member bearing surfaces have a radius exceeding the radius of the rounded transitions of the vertical walls into the said bearing surfaces.
US11155278B2 Bogie, rail vehicle having same, and rail transport system
The present disclosure provides a bogie, a rail vehicle having same, and a rail transport system. The bogie includes: a bogie frame, where the bogie frame has a straddle recess straddling a rail; a first running wheel and a second running wheel, where the first running wheel and the second running wheel are pivotably mounted onto the bogie frame respectively and are coaxially spaced apart; a third running wheel and a fourth running wheel, where the third running wheel and the fourth running wheel are pivotably mounted onto the bogie frame respectively and are coaxially spaced apart; a driving device, where the driving device is located between the first running wheel and the second running wheel, and the first running wheel and the second running wheel are driven by the driving device; and/or the driving device is located between the third running wheel and the fourth running wheel, and the third running wheel and the fourth running wheel are driven by the driving device. The bogie according to this embodiment of the present disclosure facilitates optimization of the structure of an escape passage, and has advantages such as high space utilization, high stability, and strong weight bearing capability.
US11155276B2 Cable transportation system for transporting people and method for operating the same
A cable transportation system extends along a track and has two haul cables driven respectively by respective motors and having respective mutually aligned end portions; a vehicle with two clamping devices configured to attach the vehicle to the haul cables; a passenger station at the end sections of the haul cables; two control cams arranged respectively at the end sections of the haul cables; and two actuators configured to bring the control cams into an operating position to open the clamping devices and into a resting position in which they do not interfere with the clamping devices, the control cams being spaced apart by a distance equal to the distance between the clamping devices in such a way that when the clamping device is at the control cam, the clamping device is at the control cam.
US11155274B2 Vehicle travel control method and vehicle travel control device
A travel-lane determination unit determines whether a vehicle is going to enter a traffic lane on which a toll booth is provided. After it is determined that the vehicle is going to enter the traffic lane, a travel control unit stops the vehicle at a position before the toll booth in a travel direction of the vehicle.
US11155273B2 Method and apparatus for assessing comfort level of driving system
Illustrative embodiments of the disclosure provide a method and apparatus for assessing a comfort level of a driving system. A method for generating an assessment model for comfort level in a driving system comprises acquiring a first assessment from a user on a comfort level of at least one traveling operation of the driving system, and acquiring a measurement of a traveling indicator of the driving system when performing the at least one traveling operation. The method further comprises generating the assessment model for the comfort level in the driving system based on the first assessment, the measurement of the traveling indicator, and a second assessment from the user on an overall comfort level of the driving system.
US11155272B2 Estimating apparatus
An odometry acquiring unit acquires odometry information including a yaw rate applied to a vehicle and a steering angle of the vehicle. An estimate calculating unit calculates an estimate of a turning radius based on the steering angle and the yaw rate acquired by the odometry acquiring unit. A change rate calculating unit calculates a yaw change rate representing a degree of change in the yaw rate acquired by the odometry acquiring unit. A contribution adjusting unit makes an adjustment of decreasing a contribution of the yaw rate and increasing a contribution of the steering angle, to calculation of an estimate performed by the estimate calculating unit, as the yaw change rate increases.
US11155269B1 Apparatuses, systems and methods for determining distracted drivers associated with vehicle driving routes
Apparatuses, systems and methods are provided for determining vehicle driver distractions. More particularly, apparatuses, systems and methods are provided for determining distracted drivers associated with vehicle driving routes based on postures of vehicle occupants.
US11155266B2 Active roll control apparatus and method
An active roll control apparatus is provided. The apparatus includes a first actuator that is disposed adjacent to front wheels or rear wheels and is configured to adjust roll stiffness. A controller operates the first actuator in a reverse phase control manner in a roll angle increasing direction when a vehicle is in a low-friction turning driving state.
US11155264B2 Systems and methods for determining driving action in autonomous driving
The present disclosure relates to systems and methods for determining a driving action in autonomous driving. The systems may obtain driving information associated with a vehicle; determine a state of the vehicle; determine one or more candidate driving actions and one or more evaluation values corresponding to the one or more candidate driving actions based on the driving information and the state of the vehicle by using a trained driving-action model; select a target driving action from the one or more candidate driving actions based on the one or more evaluation values; determine a target driving path based on the target driving action; and send signals to a control component of the vehicle to direct the vehicle to take the target driving action to follow the target driving path.
US11155261B2 Vehicle control device, vehicle control method, and recording medium
A vehicle control device receives a collision detection signal indicating that a vehicle collides with an object from a collision detection device. The vehicle control device measures a distance that the vehicle moves from a collision point when the collision detection signal is received. The vehicle control device limits a running of the vehicle when the movement distance from the collision point exceeds a predetermined threshold value, and does not limit the running of the vehicle when the movement distance from the collision point is the predetermined value or less.
US11155258B2 System and method for radar cross traffic tracking and maneuver risk estimation
A risk maneuver assessment system and method to generate a perception of an environment of a vehicle and a behavior decision making model for the vehicle; a sensor system configured to provide the sensor input in the environment for filtering target objects; one or more modules configured to map and track target objects to make a candidate detection from multiple candidate detections of a true candidate detection as the tracked target object; apply a Markov Random Field (MRF) algorithm for recognizing a current situation of the vehicle and predict a risk of executing a planned vehicle maneuver at the true detection of the dynamically tracked target; apply mapping functions to sensed data of the environment for configuring a machine learning model of decision making behavior of the vehicle; and apply adaptive threshold to cells of an occupancy grid for representing an area of tracking of objects within the vehicle environment.
US11155254B2 Braking device for vehicle
A braking device includes a stroke simulator, a hydraulic pressure generation unit, a reaction hydraulic pressure detection unit, a master hydraulic pressure detection unit, and a bottoming determination unit. The stroke simulator includes a cylinder and a piston slidably movable inside the cylinder in conjunction with an operation of a brake operation member. The stroke simulator causes a reaction force chamber to generate a reaction hydraulic pressure and applies a reaction force. The hydraulic pressure generation unit generates a master hydraulic pressure by driving a master piston and supplies a hydraulic pressure to a wheel cylinder. The reaction hydraulic pressure detection unit detects the reaction hydraulic pressure. The master hydraulic pressure detection unit detects the master hydraulic pressure. The bottoming determination unit determines whether the master piston is in a bottoming state based on the reaction hydraulic pressure and the master hydraulic pressure.
US11155253B2 Electropneumatic parking brake unit having a pneumatically switchable piston valve
An electropneumatic parking brake system for a utility vehicle includes a pilot module configured to control at least a first control pressure. The pilot module has a pilot store connection configured to receive a store pressure from a compressed air device and at least one pilot valve combination. The electropneumatic parking brake system further includes at least one manually actuatable piston valve connected to a valve store connection and having a parking brake connection. The parking brake connection is ventilated in a first switching position of the piston valve and a parking brake pressure at the parking brake connection is controllable in a second switching position of the piston valve. The piston valve has a first pneumatic control connection at which the first control pressure is configured to be controlled in order to pneumatically switch the piston valve.
US11155249B2 Systems and methods for causing a vehicle response based on traffic light detection
A traffic light detection system for a vehicle is provided. The system may include at least one processing device programmed to receive, from at least one image capture device, a plurality of images representative of an area forward of the vehicle, the area including a traffic light fixture having at least one traffic light. The at least one processing device may also be programmed to analyze at least one of the plurality of images to determine a status of the at least one traffic light, and determine an estimated amount of time until the vehicle will reach an intersection associated with the traffic light fixture. The at least one processing device may further be programmed to cause a system response based on the status of at least one traffic light and the estimated amount of time until the vehicle will reach the intersection.
US11155245B2 Method and system for washing a vehicle
A wash equipment assembly for a car wash and method of operating the equipment are described. For example, the assembly includes a cleaning element configured to clean a vehicle, an arm assembly operably attached to the cleaning element and configured to move the cleaning element to a vehicle cleaning position, the arm movably fixed to a support at a first end and the cleaning element mounted on the arm at a second end, a controlled locator for positioning the arm relative to the support such that the cleaning equipment is moved to the vehicle cleaning position, and a sensor for evaluating an actual orientation of the cleaning element relative to a default orientation of the cleaning element. In certain implementations, the controlled locator can modify the position of the arm in response to a signal from the sensor, thereby providing a closed loop control system.
US11155244B2 Foreign material removing device and vehicle provided with this foreign material removing device
A foreign matter removal device (1) is configured to remove foreign matters on a lens (101) of an in-vehicle camera (100) attached to a vehicle so that the lens (101) of the in-vehicle camera (100) is exposed toward an outside of a body panel of the vehicle. The foreign matter removal device includes a single-cylinder type reciprocating pump (5) configured to generate high-pressure air and a nozzle (22) configured to inject the high-pressure air toward the lens (101). A volume of an internal space of the pump is 10 cm3 or less. Exhaust time (t1) per cycle required for exhausting the air in the internal space is 0.03 seconds or less.
US11155243B2 Optical system to facilitate vehicle operation, cleaning system to clean an optical element of the optical system and hollow protective plastic enclosure for use therein
An optical system to facilitate vehicle operation, a cleaning system to clean an optical element of the optical system and a hollow, protective plastic enclosure for use therein are provided. The cleaning system includes a flexible house having first and second ends, a nozzle fluidly coupled to the hose at the first end of the hose and a hollow protective plastic enclosure having a passageway extending through the enclosure and housing a portion of the hose within the passageway. The enclosure is configured to receive a camera assembly within an interior of the enclosure. The nozzle is configured and positioned at the first end of the hose to direct the flow of a cleaning fluid therethrough to an exterior surface of a transparent optical element to clean the exterior surface to allow the camera assembly to have an unobstructed view of an environment outside the vehicle.
US11155241B2 Windshield wiper blade
A wiper blade including an elongate wiper strip, an elastic backing element and a mounting base. The wiper strip including a lip, a wide portion, and narrower intermediate portion between the lip and the wide portion. The backing element having a top portion from which two legs descend, such that each leg includes a claw that extends towards the opposite leg and has ends that define a gap sized to receive the intermediate portion of the wiper strip. The top portion, legs and claws of defining a wiper strip cavity where the wide portion of the wiper strip is disposed. The mounting base disposed on a section of the backing element and capable of connecting the wiper blade to a wiper arm and receiving force from same, such that the mounting base applies the force from the wiper arm to the backing element, which distributes same along the wiper strip.
US11155238B2 Systems and methods for determining device location for passive entry and vehicle startup
A transceiver is configured to: pair with a mobile device; and transmit a predetermined signal from an antenna to the mobile device. A zone module is configured to: receive a signal from the mobile device in response to the predetermined signal; and based on the signal, select a zone within which the mobile device is present from a group consisting of: a first zone that is defined by a first radius from the antenna; a second zone that excludes the first zone and that is defined by a second radius from the antenna, where the second radius is greater than the first radius; and a third zone that is radially outward of the second zone and that excludes the first and second zones.
US11155237B2 Perimeter alert defense system
Perimeter alert defense systems and methods are described.
US11155234B2 Gas generator, airbag module and motor vehicle safety system
The invention relates to an inflator (10) comprising an ignition unit (30) having an igniter (31), a chamber (20) arranged axially downstream of the ignition unit (30) and a diffuser chamber (40) arranged axially downstream of the chamber (20) which is comprised by a diffuser (42), wherein a combustion chamber screen (50) having an igniter-side end (51) and a diffuser-side end (52) is disposed in the chamber (20), the combustion chamber screen (50) being tapered, especially conically, in the longitudinal direction (L) of the inflator (10) from the igniter (31) toward the diffuser (42).
US11155232B2 Folding method of far-side airbag apparatus
A folding method of a far-side airbag apparatus may include: a first folding step of folding an upper portion of an airbag sheet toward an inboard side; a second folding step of folding both widthwise sides of the airbag sheet toward an outboard side; a third folding step of folding the upper portion of the airbag sheet toward the inboard side; and a fourth folding step of roll-folding the airbag sheet.
US11155231B2 Curtain airbag device for vehicle
A restraint performance improvement portion of a curtain airbag device for a vehicle is provided at a location of a lower end portion of a curtain airbag which location corresponds with a vehicle seat when the vehicle seat is in a comfortable state. The restraint performance improvement portion inhibits a head area of a vehicle occupant from slipping past the curtain airbag to a vehicle width direction outer side thereof when the vehicle occupant is being restrained.
US11155230B2 Pivoting center display for minimizing airbag interaction
A system and method for deploying an airbag includes an instrument panel and an airbag assembly disposed within the instrument panel. The airbag assembly includes the airbag and a door disposed within the instrument panel. A center display screen is pivotally disposed relative to the instrument panel. The airbag assembly includes a first state wherein the door is closed and the airbag is folded and a transitional state wherein the door is opened, a least a portion of the airbag is unfolded and contacts the display to rotate the center display screen relative to the instrument panel.
US11155229B2 Device for removably mounting an airbag module
A device for removably mounting an airbag module includes at least two hooks connected to one of the airbag module or the steering wheel. The hooks cooperate with insertion elements located on the other of the airbag module or the steering wheel. A resilient ring forms elements for holding the hooks in zones of interaction. The resilient ring includes: first portions that extend in the interaction zones, and a second portion. The mounting device further includes elements for guiding the resilient ring that cause displacement of the first portions out of the zones of interaction, during displacement of the second portion in a direction away from an axis of rotation of the steering wheel.
US11155228B2 Vehicle safety device
A vehicle safety device has a connective rod having a proximal end and a distal end, the solenoid assembly connected with the distal end of the connective rod, and the solenoid assembly comprising a solenoid. The vehicle safety device includes a reinforced pad comprising a rigid support plate and a pad portion, the reinforced pad connected with the solenoid assembly. The vehicle safety device further includes an activation assembly comprising a relay device configured to transmit an activation signal to the solenoid.
US11155227B2 Occupant monitoring device for vehicle and occupant protection system for vehicle
An occupant monitoring device for a vehicle is configured to monitor an occupant sitting on a seat provided in the vehicle and includes a light projector, an imaging device, and a processor. The light projector is configured to project light toward the occupant sitting on the seat. The imaging device is configured to capture an image of the occupant sitting on the seat. The processor is configured to control the light projector and the imaging device to capture the image of the occupant sitting on the seat. In a case where a collision of the vehicle is neither predicted nor detected, the processor causes the imaging device to capture an image of behavior of the occupant corresponding to either one of travel control and behavior of the vehicle so as to change occupant protection control.
US11155226B2 Vehicle cabin monitoring system
A system and method for calibrating a vision system includes a selective wavelength interactive material located within the cabin of the vehicle and a control system in communication with the camera. The material is arranged as a pattern having pattern elements configured to reflect or absorb infrared light from an infrared light source. The control system is configured compare a captured image from the vision system that shows the pattern elements and calibrate the vision system based on a comparison of the captured image. Additionally or alternatively, the selective wavelength interactive material is disposed on a surface of a safety belt and the control system is configured to determine that an occupant seated in a seat is wearing a safety belt associated with the seat when the captured images show that the selective wavelength interactive material on the surface of the safety belt extending across the occupant seated.
US11155224B2 Bumper reinforcement for automobile
To compensate for a decrease in reaction force of a bumper reinforcement, which is made of an aluminum alloy extrusion having two end portions subjected to bend forming and crushed portions on the respective end portions, against an impact load in end impact involved in crushing, and compensate for a decrease in energy absorption amount of the bumper reinforcement. Assuming a space between two flanges includes a first region from a center line of the thickness between the flanges to an outer flange and a second region from the center line to an inner flange in a cross section of the crushed portion perpendicular to an extrusion direction, area of the webs located in one (for example, the first region) of the two regions is larger than area of the webs located in the other region (for example, the second region).
US11155221B2 Power supply device for vehicle
A power supply device for a vehicle includes first and second systems, a switch disposed between the systems, and first and second controllers. The first system includes a first power supply and a first electrical apparatus. The second system includes a second power supply and a second electrical apparatus. The first mode controller executes a low power mode where the switch is turned on to supply electric power from one of the first and second power supplies to the first and second electrical apparatuses. The second mode controller executes a high power mode where the switch is turned off to supply electric power from the first and second power supplies to the first and second electrical apparatuses, respectively. When a discharge electric current of the second power supply exceeds a threshold during the low power mode, the second mode controller switches the power supply mode to the high power mode.
US11155219B2 Automobile door trim
There is provided a door trim including: an armrest; an ornament member coupled to the armrest; and a planar heater configured to warm the armrest or the ornament member. The planar heater is disposed between a resin core member and a surface member which form the armrest or the ornament member, and includes a nonwoven fabric and a heating wire fixed to the nonwoven fabric. The nonwoven fabric includes first and second bonded parts and a connection part connecting between the first and second bonded parts. The second bonded part is routed to be disposed on the back surface side of the armrest (the back surface side of the ornament member) by the connection part being inserted into an interface gap between the armrest and the ornament member. A thermostat is mounted on the second bonded part.
US11155217B2 Vehicular rack having modular design with outside handle and quick release
A bicycle carrier convertible between a first configuration in which one or more bicycles are accommodated and a second extended configuration in which one or more additional bicycles are accommodated for transport on a carrying vehicle. The bicycle carrier can include a vehicle engaging frame configured to be mounted on a carrying vehicle. An elongate rearward extending support member can be coupled to the frame at a proximate end of the support member by a variably configurable hub configured to set the support member in a plurality of orientations relative to the frame. A manual actuator can be operably coupled to the variably configurable hub by a linkage. A distal end of the support member can be positioned away from the frame and configured to be alternately coupled to the actuator, or an add-on support member that accommodates one or more additional bicycles coupled to the bicycle carrier.
US11155216B2 Retaining device for vehicle racks
A retaining device for securing one or more accessory racks to a base rack on a vehicle is provided herein. The device comprises a housing member that extends through the one or more accessory racks and into the base rack, a head, secured to the housing member that engages one or other of the racks, a detent that engages the other of the racks, and an engagement mechanism that extends the detent and pulls it toward the head. The device may further comprise a lock that secures the detent in a clamping position. The lock may comprise a ratchet and pawl arrangement defined by first and second levered tabs disposed on the head, the first tab being operably connected to the engagement mechanism. An ATV comprising one or more accessory racks secured to a base rack by a retaining device as described herein is also provided.
US11155214B2 Roof rack and vehicle including the same
A roof rack mounted on a roof panel of a vehicle includes a main body including a rail that extends along a lengthwise direction and forms the main body and support parts provided on opposite longitudinal end portions of the rail in the lengthwise direction, a hollow profile that extends along the lengthwise direction of the rail and that is integrally formed inside the rail, and a cap mounted on at least one of opposite longitudinal end portions of the hollow profile or disposed inside the main body.
US11155210B2 Vehicular driving assist system including multiple cameras and radar sensor
A vehicular driving assist system includes a rearward viewing camera, a driver-side camera, a passenger-side camera and at least one radar sensor. Image data captured by the cameras is provided to a control and radar data captured by the radar sensor is provided to the control. The control processes the provided captured data to determine a potential hazard presented by rear-approaching traffic. The control outputs video image data for display by a display device of the equipped vehicle. The display device includes a video display screen that displays video images for viewing by a driver of the equipped vehicle during operation of the equipped vehicle. The control processes provided captured image data and provided captured radar data to alert the driver to the determined potential hazard presented by the rear-approaching traffic in the side traffic lane adjacent to the traffic lane being traveled by the equipped vehicle.
US11155208B2 Image display unit
In order to achieve an image display unit having excellent degree of freedom in designing the position of a display image, an image display unit (1A) is provided with: an imaging unit (10) configured to capture an image of a space to be viewed; an image display device (11) configured to display an image captured by the imaging unit (10) in a display area in real time; and an image forming unit configured to form an image in a space where there is no screen by projecting the image displayed by the image display device (11).
US11155207B2 System and method for vehicle image collection
The present document describes a vehicle-side image capturing system and method that is capable of improving qualities of images captured at vehicle-side. The system includes: a controller, a plurality of cameras, a light sensor and an encoder each connected to the controller. The controller is configured to: receive an illumination intensity of a current environment from the light sensor, select one of the plurality of cameras that is adapted to the illumination intensity as a target camera, activate when the target camera is different from a currently operating camera, deactivate the currently operating camera then configure the target camera as an operating camera for image capturing, and receive images captured by the operating camera and transmit the received images to the encoder. The encoder is configured to encode the received images and transmit the encoded images.
US11155206B2 Proximity sensor
A proximity sensor installed inside a vehicle can include: an outer frame formed of a first non-conductive substance and including a first metal layer; an inner frame formed of a second non-conductive substance, including a second metal layer, and disposed in an interior of the outer frame; a sensor electrode contacting the second metal layer; and a sensor Integrated Circuit (IC) connected to the sensor electrode and configured to detect an approach or a contact of a user's hand. The first metal layer can be connected to the ground (GND) so as to confine a sensing field of the sensor electrode to the interior of the outer frame.
US11155204B2 Gas hauler with an awning with a built in light
A tank trailer includes a tank having an outer surface face and an inner surface and a central longitudinal vertical plane extending between the first end and the second end. The outer surface faces away from the central longitudinal vertical plane and the inner surface faces towards the central longitudinal vertical plane. The outer surface and the inner surface define an interior volume adapted to be filled with material. The tank trailer may further include a set of ground-engaging wheels supporting the tank trailer from below, a bar positioned proximate the outer surface of the tank and a light source provided on the bar. The tank may further include a frame member operatively engaged with the bar and a sheet material extending between the bar and the frame member. The frame member is movable between a first position and a second position.
US11155203B2 Predictive control system for intelligent head lamp and method thereof
A front imaging unit configured to obtain a front image by capturing an image of a view in front of a host vehicle, a detection sensor configured to simultaneously monitor front lateral and rear lateral blind spots of the host vehicle, a head lamp configured to radiate a high beam in front of the host vehicle on the basis of a radiation region set through the front imaging unit and the detection sensor, a vehicle control unit configured to generate a control command to control, in advance, a radiation form of the head lamp on the basis of information of the front imaging unit and the detection sensor, and a driving unit configured to drive the head lamp on the basis of the control command of the vehicle control unit.
US11155202B2 Vehicle having a rear light having a screen with tab with visible markings
A motor vehicle has a rear light to which a screen, which covers a light housing of the rear light is attached in the region of a water channel arranged or formed adjacent to a rear opening of the motor vehicle. Advantageously, the screen has a passage opening or a cutout that, in the mounted state of the screen, is occupied by a tab of the light housing of the rear light whose shape is complementary to that of the passage opening or the cutout of the screen. The marks relating to the rear light are applied to a tab surface of the tab, and/or are introduced into the tab surface, that is visible from outside the vehicle when the screen is in its mounted state.
US11155200B2 Load hauler
A mat hauler, comprising a fifth wheel tractor having a chassis and a fifth wheel hitch. A mat elevating mechanism is secured to the chassis. A frame is supported by the mat elevating mechanism. The frame provides a minimum of four mat contacting elements. The mat elevating mechanism may be pneumatic.
US11155196B2 Child restraint with cupholder
A child restraint includes a juvenile seat having a seat bottom and a seat back extending upwardly from the seat bottom. The juvenile seat further includes a cupholder coupled to the seat bottom.
US11155182B2 Computing systems and methods for controlling current in vehicle motors
A motor controller is described that is coupled to a drive motor and a battery pack of a vehicle. The motor controller is configured to determine a maximum discharge current of the battery pack and a rotational velocity of the drive motor. Based on the determined rotational velocity of the drive motor, the motor controller is configured to identify a curve that defines a relationship between the maximum discharge current of the battery pack and a drive current limit of the motor controller. Based on the identified curve and the determined maximum discharge current of the battery pack, the motor controller is configured to determine the drive current limit of the motor controller. The motor controller is further configured to convert a discharge current from the battery pack to a drive current subject to the determined drive current limit and supply the drive current to the drive motor.
US11155177B2 Charging station monitoring system
A charging station monitoring system comprising: a sensing device, a digital camera and a communication device which are arranged at a charging apparatus of a charging station, the sensing device and the digital camera each having a sensing range covering a parking lot associated with the charging apparatus and an area around the parking lot; and a controller configured to determine an occupation state of the parking lot and/or detect and record an action of a third party or foreign object based on sensed information from the sensing device and the digital camera.
US11155173B2 Electric vehicle
An electric vehicle disclosed herein may include an AC inlet connectable with an AC power supply outside the vehicle, a main battery, and a power unit. The power unit may be connected to the main battery by a first battery power cable and a second battery power cable, and connected to the AC inlet by an AC inlet power cable. Inside the power unit, the AC inlet power cable may be connected to the second battery power cable via an AC/DC converter. Further, the first battery power cable may be connected to a power cable of a device other than the AC/DC converter.
US11155172B2 Power supply system for driving vehicle
The present invention discloses a power supply system capable of supplying electric power to a vehicle, in particular, an electric vehicle, while reducing the number of components and improving stability. An embodiment of the present invention discloses a power supply system comprising: a battery comprising battery cells; a first switching device formed between one electrode of the battery and a power load unit comprising a motor that receives power from the battery; a pre-charge resistor having one end electrically connected to the other electrode of the battery; and a second switching device formed between the other end of the pre-charge resistor and the other electrode of the battery.
US11155157B2 Locking system for a fuel compartment assembly of a work vehicle
A locking system for a fuel compartment assembly of a work vehicle, the locking system having a housing at least partially defining a fuel access compartment, a door pivotally coupled to the housing and movable between an opened position, at which the door provides access to the fuel access compartment, and a closed position, at which the door blocks access to the fuel access compartment, and a locking assembly configured to lock the door at the closed position. The locking assembly includes a catch fixed to the housing and positioned within the fuel access compartment, and a latch arm pivotably coupled to the door at a pivot point defined between first and second ends of the latch arm, the pivot point defining a first pivot axis, where the latch arm is configured to be pivoted about the first pivot axis to be selectively engaged and disengaged with the catch.
US11155154B1 Multi-pump driven single-motor hydro-mechanical hybrid transmission device and control method thereof
A multi-pump driven single-motor hydro-mechanical hybrid transmission device includes an input shaft, a planetary gear split mechanism, a hydraulic transmission system, a planetary gear convergence mechanism, and an output shaft. The input shaft is connected to the hydraulic transmission system and the planetary gear convergence mechanism through the planetary gear split mechanism. The hydraulic transmission system and the planetary gear convergence mechanism are both connected to the output shaft. The hydraulic transmission system includes a multi-pump driving mechanism, a fixed displacement motor mechanism, and a hydraulic transmission output mechanism. The multi-pump driving mechanism is connected to the fixed displacement motor mechanism. The fixed displacement motor mechanism is connected to the planetary gear convergence mechanism and is connected to the output shaft through the hydraulic transmission output mechanism.
US11155149B2 Battery and fuel tank arrangement structure of hybrid vehicle
A battery is mounted in front of the vehicle along a longitudinal direction of the vehicle and mounted on the vehicle body, and the fuel tank is mounted in the vehicle body by disposing the fuel tank at the rear side in the longitudinal direction of the vehicle such that expansion of passenger compartment and vehicle body stability may be achieved.
US11155147B2 Auxiliary power device
An auxiliary power device includes a housing, a motor supported by the housing, and a wheel engaged with the motor. The wheel has a rotational axis and a spindle on the rotational axis. The housing defines a track adjustably supporting the spindle of the wheel. The adjustability of the spindle supported by the track in the housing allows for the wheel to adjust relative to the housing and allows the auxiliary power device to be used on a variety of vehicles.
US11155146B2 Automated tarping device and system
An automated tarping device and system is provided, wherein the at least two swing arm devices of the tarping system are configured to be enclosed within the side walls and frame of the trailer, when the automated tarping system is in a fully closed position so as to cover the opening of the trailer with the tarp assembly. When the system is in a closed position, the swing arm devices themselves are covered by the tarp. The system also includes a tarp assembly comprising a flexible tarp and first and second resilient actuating ribs. The attaching member of each swing arm device releasably couples to an actuating rib, and the tarp and the first and second actuating ribs of the tarp assembly are transversely disposed across, so as to cover, the opening of the trailer when the arm devices are in the closed position.
US11155135B2 Traction system for railcar movers
A traction system is provided for a rail draft vehicle including an engine with a driveshaft, at least a pair of rubber-tired traction wheels, and at least one rail guide wheel pressurized relative to the vehicle by at least one fluid-powered cylinder. Included in the system are a programmable processor connected to a driveshaft speed sensor, a rail guide wheel speed sensor, an engine throttle controller, a fluid-powered cylinder controller and a vehicle control panel. The processor is constructed and arranged for automatically adjusting the engine throttle controller in coordination with the fluid-powered cylinder controller for achieving movement of the rail draft vehicle from a dead stop position by increasing applied vehicle weight upon the traction wheels by the at least one fluid-powered cylinder and adjusting engine RPM's until the vehicle begins movement as detected by the rail guide wheel speed sensor.
US11155132B2 Weight distribution tag trailer
The present invention comprises a weight distribution tag trailer, having at least some of the following features: (a) a frame assembly, including beams and cross beams and side axle beams, (b) an axle coupled to the frame assembly, (c) shims for optional position between an axle assembly and the side axle beams to allow adjustment of load and balance (d) at least two wheels rotatably mounted to the axle, wherein at least one beam includes an end complementarily sized to be received by a vehicle receiver hitch assembly, and at least one other beam includes a clamp for coupling the beam to a cross frame of the vehicle receiver hitch.
US11155129B2 Wheel clamp assembly for semi-autonomous tire changer machine
A tire changer machine, and method of operation, configured with a tire-engaging wheel clamp assembly to secure a wheel assembly consisting of a wheel rim and tire mounted thereon to a drive assembly, and for demounting of the tire from the wheel rim. Upon dismounting of the tire from the wheel rim, a recessed surface and annular flange of the tire-engaging wheel clamp assembly is configured to catch and retain a rim or bead of the demounted tire, restricting movement of the tire upon dismounting from the wheel rim, until retrieved by an operator.
US11155128B2 Wheel monitoring device
The invention relates to a wheel monitoring device (D) of the type comprising a housing (100) formed from a hollow core (101) containing different components including an electronic board (500) and a power supply battery (600) for said board (500), said housing (100) being positioned inside the tire and fixed to the internal portion (220) of the valve (200) fitted on the wheel, a polymer material filling in the free volume. The device is remarkable in that the housing (100) is preformed so as to provide at least two different superposed parallel installation planes (P1, P2) on which the different components are distributed, said housing (100) being preformed with a lateral opening to enable the different components to slide laterally into their appropriate installation plane (P1, P2).
US11155122B2 Pneumatic tire
A pneumatic tire includes a tread portion being provided with blocks which are provided with sipes. When the tread portion is virtually divided into a crown area having a ¼ tread ground-contact width centered on a tire equator, a pair of middle areas each having a ⅛ tread ground-contact width and being adjacent to axially each side of the crown area and a pair of inner shoulder areas each having a ⅛ tread ground-contact width and being adjacent to axially outside the middle areas, the sipes comprise crown sipes having main portions included in the crown area, middle sipes having main portions included in the middle areas and shoulder sipes having main portions included in the inner shoulder areas. Depths of the crown sipes are smaller than depths of the middle sipes, and depths of the shoulder sipes are smaller than the depths of the middle sipes.
US11155119B2 Traction wheel apparatus with non-uniform tread teeth
The present disclosure relates to a wheel apparatus that includes a rim module coupleable to an axle and a solid tire module that extends from the rim module. The solid tire module includes a plurality of tread teeth that form a peripheral edge. The peripheral edge forms at least a portion of a tire profile. Each tread tooth of the plurality of tread teeth has a spatial specification that includes a circumferential width, a radial height, an edge shape, and a circumferential gap width. The spatial specifications of the plurality of tread teeth are non-uniform. In one embodiment, the solid tire module has a non-circular rotational trace. In another embodiment, at least a circumferential region of the peripheral edge comprises a sequence of tread teeth having sequentially increasing radial height.
US11155116B2 Cap or hat decoration system and method
Embodiments include a cap or hat decoration method by providing a press including a lower platen and upper platen, and coupling a pad to the lower platen, where the pad is dimensioned based on one or more dimensions of the cap or hat, and positioning the cap or hat onto at least a portion of the pad. Further, the method includes positioning at least one decoration onto at least a portion of the cap or hat, where the at least one decoration includes a heat-activated adhesive, and heating and compressing the decoration onto the cap or hat by compressing the cap or hat and decoration between the lower platen and upper platen.
US11155115B2 Lettering film
A lettering film includes a lettering layer, a middle layer and a substrate layer. The lettering layer, the middle layer and the substrate layer are separably adhered to each other. The lettering layer has cutting stripes. The lettering film can be cut into characters and/or figures. The cutting marks of the characters and/or figures cut the lettering layer and the middle layer without cutting off the substrate layer. The lettering layer of the lettering film is adhered to an article and then the substrate layer and the middle layer are peeled off, whereby the lettering layer is adhered to the article and the cut characters and/or figures are adhered to the surface of the article.
US11155110B2 Inkjet printer with flow adjuster
An inkjet printer includes: a conveyer configured to convey a print medium; an inkjet head configured to eject ink to the print medium conveyed by the conveyer; a flow adjuster configured to adjust strength of an air flow in an under-head space which is a space between the inkjet head and the conveyer; and a controller configured to control the flow adjuster such that the smaller a satellite droplet generated from the ink ejected by the inkjet head is, the stronger the air flow in the under-head space is.
US11155109B2 Processing device, control method of processing device, and recording system
A processing device includes a medium supporting portion having a support surface for supporting at least a front end portion of a transported medium, an aligning portion for aligning the medium supported by the medium supporting portion, a stacking portion provided below the medium supporting portion in a vertical direction, having a stacking surface on which the medium dropped from the medium supporting portion is stacked, and configured to move up and down, and a pressing portion having a pressing surface facing the support surface, the pressing surface being configured to move between a first position and a second position closer to the support surface than the first position, in which the pressing portion is disposed at the first position when the medium is transported to the medium supporting portion, and is disposed at the second position after the aligning portion aligns the medium on the medium supporting portion.
US11155108B2 Image recording apparatus
An image recording apparatus includes: a casing having an internal space; a conveying passage formed inside the casing; a first roller pair positioned in the conveying passage, having a driving roller and a driven roller, and configured to pinch a sheet and to convey the sheet in a conveying orientation; a platen positioned on a downstream side in the conveying orientation of the first roller pair, and having a supporting surface supporting the sheet; a recording part positioned above the platen and configured to record an image on the sheet supported by the platen; a second roller pair which is located on the downstream side in the conveying orientation of the supporting surface of the platen, and which is configured to pinch the sheet and to convey the sheet; and a moving mechanism configured to move the platen to a printing position and to a release position.
US11155106B2 Image forming apparatus
Provided is an image forming apparatus in which paper is stably transferred from a belt transportation unit on an upstream side to a belt transportation unit on a downstream side. Problems as described above are solved by using the image forming apparatus including a first belt transportation unit, a second belt transportation unit, and a third belt transportation unit that transports a recording medium received from the first belt transportation unit to transfer the recording medium to the second belt transportation unit, in which a diameter of an upstream side pulley of the third belt transportation unit is smaller than a diameter of a downstream side pulley of the first belt transportation unit and a diameter of a downstream side pulley of the third belt transportation unit is smaller than a diameter of an upstream side pulley of the second belt transportation unit.
US11155094B2 Rotatable service assembly for fluid ejection die
A fluid ejection device includes a fluid ejection assembly including a fluid ejection die, and a service assembly to be rotated to different positions relative to the fluid ejection assembly for different service operations of the fluid ejection die.
US11155088B2 Liquid ejection head
A liquid ejection head includes: individual passages each having a nozzle; supply liquid passages each communicating with an individual inlet of a corresponding one of the individual passages; return liquid passages each communicating with an individual outlet of a corresponding one of the individual passages; a first supply coupling liquid passage coupling the supply liquid passages to each other and communicating with a first inlet of each of the supply liquid passages; and a second supply coupling liquid passage coupling the supply liquid passages to each other and communicating with a second inlet of each of the supply liquid passages. In each of the supply liquid passages, the individual inlet of the corresponding one of the individual passages is located between the first inlet and the second inlet.
US11155087B2 Liquid discharge head
There is provide a liquid discharge head including: a supply manifold; a feedback manifold; and a plurality of individual flow channels having: a supply portion, a descender portion, and a feedback portion. The supply manifold has a plurality of supply ports, and the feedback manifold has a plurality of feedback ports. At least part of the supply manifold overlaps with the feedback manifold in the second direction. The plurality of pressure chambers have first pressure chambers forming a first pressure chamber array and second pressure chambers forming a second pressure chamber array. The first pressure chamber array is arranged at one side, of the supply manifold, in a third direction and the second pressure chamber array is arranged at the other side, of the supply manifold, in the third direction. The first pressure chamber array and the second pressure chamber array are connected to the supply manifold.
US11155083B2 Member transfer method and manufacturing method for liquid ejection head
A member transfer method includes sticking a member supported at a support to an object, thinning the support after the sticking of the member to the object, and removing the support from the member after the thinning of the support.
US11155079B2 Data-driven and customized predictive resource replenishment
Current usage metrics are maintained for a consumable of a resource. A history of usage metrics associated with consumable and other consumables used by the resource are acquired for the resource. A predicted date for which the consumable will need a replacement consumable is predicted based on one or more of the current usage metrics and the history of usage metrics. The replacement consumable is ordered on a second date that precedes the predicted date ensuring that the replacement consumable arrives at a site where the resource is located before the predicted date.
US11155078B2 Printing apparatus and inspection method therefor
A printing apparatus prints by discharging ink to a transfer member from a first printhead, discharging a transfer accelerator to the ink from a second printhead, and transferring an image formed on the transfer member to a print medium. When inspecting a discharge state of each of plural nozzles provided in each of the first and second printheads, the apparatus controls the second printhead so as to discharge the transfer accelerator from at least one nozzle of the second printhead to a discharge area of the transfer member to which the ink is discharged by the first printhead for inspection of the discharge states of the plural nozzles of the first printhead, while inspecting a discharge state of a nozzle different from the at least one nozzle of the second printhead by discharging the transfer accelerator from the nozzle.
US11155071B2 Methods and keyway supports for additive manufacturing
The present disclosure generally relates to methods for additive manufacturing (AM) that utilize support structure in the process of building objects that may be removed by rotating the support structure to a second orientation before removal, as well as novel support structures to be used within these AM processes. The support structures are fabricated in a first orientation and then rotated to the second orientation. The support structures are removed by passing through an outlet of the object.
US11155070B2 Prepreg debacker and method of layup
A method of removing backing film from a sheet element is provided. The sheet element has a preimpregnated layer, and sheets of backing film are adhered to the top and bottom of the preimpregnated layer. The backing film has a different coefficient of thermal expansion than the preimpregnated layer, and a plane of the sheet element is defined by the peripheral edge. A shear strain is created between the backing films and the preimpregnated layer by cooling the sheet element. A fluid stream is directed at a portion of the peripheral edge, the fluid stream being directed in the plane of the sheet element. The fluid stream causes the backing films to separate from the top and bottom of the preimpregnated layer. A differential pressure is simultaneously applied to the backing films relative to the fluid stream to cause the backing films to be removed from the preimpregnated layer.
US11155069B2 Method and system of forming a composite laminate
A method and associated system for forming composite materials is presented, including providing a composite charge having applied release films to top and bottom surfaces and positioned on a contoured forming tool such that a portion of the composite charge over hangs a second upper surface of forming tool. A fairing bar abuts the forming tool that has an uppermost surface positioned above the second upper surface of the forming tool. The combination of the positioning of the failing bar and the use of release film in contact with the composite charge allows the composite charge to conform to the contoured forming tool without bridging or wrinkling the composite charge when a forming membrane and applied vacuum are used.
US11155065B2 Compositions having a matrix and encapsulated phase change materials dispersed therein, and electronic devices assembled therewith
Provided herein are compositions made from a matrix and encapsulated phase change material particles dispersed therein, and electronic devices assembled therewith.
US11155063B2 Stretchable structure, multilayered stretchable sheet, spun yarn, and fiber structure
An object of the present invention is to provide a stretchable structure that has stretchability together with high stress relaxation properties, and provides fit feeling with less tightening by recovering slowly after stretching. The object is achieved by a stretchable structure having the following characteristics: a tensile permanent set (PS10M) of 1% or more and 50% or less, wherein the tensile permanent set (PS10M) is a value obtained 10 minutes after 150% elongation at a tension rate of 200 mm/minute in accordance with JIS K7127, and a ratio PS1M/PS10M of 1.10 or more, wherein the PS10M is the tensile permanent set obtained 10 minutes after the elongation and the PS1M is the tensile permanent set obtained 1 minute after the elongation.
US11155062B2 Interlayer film for laminated glass and laminated glass
The present invention provides an interlayer film for laminated glass which has excellent sound insulating properties even when the thickness is reduced, and also has a low degree of orientation and low shrinkability.The invention relates to an interlayer film for laminated glass which includes at least one layer A containing a thermoplastic elastomer, wherein the thermoplastic elastomer includes a hard segment block and a soft segment block, the layer A has a sea-island phase separated structure in which the hard segment block is included as an island component and the soft segment block is included as a sea component, and the degree of orientation (1) defined by (maximum intensity value−minimum intensity value)/(maximum intensity value+minimum intensity value) based on the maximum intensity value and the minimum intensity value in an arbitrary azimuth range of 180° including the azimuth at which the intensity reaches the maximum in the azimuthal intensity distribution of periodic scattering or coherent scattering by the hard segment block or the soft segment block obtained for the layer A by small-angle X-ray scattering measurement is 0.9 or less.
US11155058B2 Laminated fabrics and protective covers with post-industrial and/or post-consumer content and methods of making laminated fabrics and protective covers with post-industrial and/or post consumer content
A method of recycling laminated fabrics and laminated fabric products and producing new laminated fabrics and laminated fabric products includes the steps of shredding scrap or used laminated fabric material, melt separating the polymers, pelletizing the melt separated polymers, extruding the pelletized material with at least one virgin material to form a film, and laminating the film to a nonwoven material to form a new laminated fabric. The scrap or recycled laminated fabric products can include plastic/polymer materials having different melting temperatures. The new laminated fabric can be utilized to produce new products, such as protective covers.
US11155051B2 Tire vulcanizing method and device
A tire vulcanizing method comprises: a step of causing a connecting body, at which an upper mold of a vulcanization mold is supported and that connects together upper end portions of upper tubes of a plurality of supporting pillars, the supporting pillars being disposed so as to be apart in a peripheral direction at a periphery of the vulcanization mold, which is formed from a lower mold and the upper mold, which is set above the lower mold, and the supporting pillars having lower tubes that are hollow and the upper tubes, which are hollow and are slidably engaged with the lower tubes, and the supporting pillars extending in a vertical direction, to, together with the upper tubes and the upper mold, approach the lower mold, and close the vulcanization mold; and a step of vulcanizing an unvulcanized tire that is accommodated at an interior of the vulcanization mold that is closed, wherein the causing the connecting body, the upper tubes and the upper mold to approach the lower mold is carried out by operating raising/lowering mechanisms that are accommodated at interiors of the supporting pillars.
US11155049B2 Composite material shaping device and composite material shaping method
According to one implementation, a composite material shaping device includes three rollers and an angle adjusting structure. The three rollers apply pressures on a laminated body of prepregs, from different directions. The prepregs are laminated in a bar shape. The angle adjusting structure continuously changes an angle of a rotating axis of at least one roller out of the three rollers. Further, according to one implementation, a composite material shaping method includes applying pressures on a laminated body of prepregs laminated in a bar shape, from different directions, using three rollers; and producing a shaped laminated body of the prepregs by continuously changing an angle of a rotating axis of at least one roller out of the three rollers.
US11155045B2 Drive system for automatic welding machine
A drive system for driving an automatic welding machine for joining the edges of sealing sheets, comprising pressing/advancing rollers located vertically opposite one another and driven by a shared drive motor, downstream of which a transmission gear mechanism is connected, and an upper pressing/advancing roller is disposed rotatably about a roller rotational axis on a tensioning arm of the automatic welding machine, which is pivotable about a tensioning arm axis, and a lower pressing/advancing roller is disposed rotatably about a roller rotational axis on a frame of the automatic welding machine, which is supported by at least two drive rollers, wherein the drive motor and the transmission gear mechanism are rigidly attached to the frame, and the drive motor comprises a motor armature including a protruding rotational shaft, and the transmission gear mechanism comprises a rotatable protruding input shaft and output shaft.
US11155043B2 Sonotrode and anvil for ultrasonic welding of plastics, method for producing a plastic container
A combination of a sonotrode and anvil, includes a sonotrode/anvil surface and a first row of sonotrode/anvil welding contact elements. The first/second series of each of the sonotrode/anvil welding contact element of a first row includes a first/second adapted lateral surface that joins at least one part of the first/second plateau surface with at least one part of the sonotrode/anvil surface side. The first/second adapted lateral surface includes a first/second curved surface positioned between the first/second plateau surface and the first/second substantially straight surface. The first/second curved surface has a convex outward arch. The welding contact element is positioned in relation to the anvil welding contact element such that the sonotrode welding contact element is positioned during welding next to the anvil welding contact element and is provided to form at least one part of a weld seam.
US11155037B2 Printer system
A printer comprising an electrical load, a control system and an electrical circuit to switchably connect the electrical load to a first phase and a second phase of a polyphase power supply. The control system monitors a first electrical current drawn by the printer on the first phase and a second electrical current drawn by the printer on the second phase. When a difference between the first electrical current and the second electrical current satisfies a threshold condition, the control system controls the electrical circuit to disconnect the electrical load from the first phase and connect the electrical load to the second phase.
US11155027B2 Layer-by-layer production of molded articles
The invention relates to a method for manufacturing molded articles consisting of at least one molded article layer, said method comprising the steps of a) putting a layer support in place for accommodating at least one molded article layer; b) applying a molded article layer to a printing plate using a shaping tool; c) positioning the printing plate and the layer support or a previously produced molded article layer relative to one another; d) curing the molded article layer such that said layer becomes a previously molded article layer, and transferring the molded article layer; e) if necessary, putting the printing plate in place for accommodating additional molded article layers and repeating steps b) to d). The invention further relates to an apparatus for carrying out the disclosed method as well as to the use of molded articles obtained thereby.
US11155026B2 Film pasting tool and film pasting method
A film pasting tool is used to paste one surface of a film on a member-to-be-pasted at a predetermined position. The tool comprises a flexible tabular body, a first adhesive part, a front surface thereof being adhesive, provided on one surface of the body, and a second adhesive part, a front surface thereof being adhesive, provided on a part of a region other than a region where the first adhesive part is provided out of one surface of the body. An other surface of the film is pastable on the front surface of the second adhesive part, and when the other surface of the film is pasted on the front surface of the second adhesive part, the front surface of the first adhesive part is exposed in such a manner that the front surface of the first adhesive part is pastable on the member-to-be-pasted.
US11155015B2 Synthetic resin microporous film and manufacturing method thereof, and separator for power storage device and power storage device
The present invention provides a synthetic resin microporous film which has excellent permeability of lithium ions, can constitute high performance power storage devices, and is less likely to cause a short circuit between a positive electrode and a negative electrode as well as rapid decrease in discharge capacity due to a dendrite even when used in high power applications. The synthetic resin microporous film of the present invention is a synthetic resin microporous film comprising a synthetic resin, the synthetic resin microporous film being stretched, the synthetic resin microporous film having, in a cross section along a thickness direction and a stretching direction of the synthetic resin microporous film: a plurality of support portions extending in the thickness direction of the synthetic resin microporous film; a plurality of fibrils formed between the support portions; and the support portions having the number of branch structures of 150 or less per 100 μm2; and the synthetic resin microporous film being configured such that micropore portions are formed in areas surrounded by the support portions and the fibrils.
US11155014B2 Injection molding apparatus and injection molding method
An injection molding apparatus includes an injection-molding mold including a fixed mold and a movable mold, the fixed mold having a gate opening into which a molding material flows, the movable mold having a cavity and being configured to be separated from the fixed mold during mold opening; a hot runner including a nozzle having a channel that guides the molding material to the gate opening, and a heater, the hot runner being disposed in the fixed mold; and a control unit that controls a temperature of the heater to adjust a temperature of the hot runner. The control unit controls the temperature of the heater to a first temperature when the molding material is injected from the hot runner to the cavity, and after the injection of the molding material is completed, controls the temperature of the heater to a second temperature that is higher than the first temperature.
US11155007B2 Nanostructures from laser-ablated nanohole templates
Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate.
US11155005B2 3D-printed tooling and methods for producing same
Techniques for 3-D printing a tooling shell for use in producing panels for a transport structure, such as an automobile, boat, aircraft, or other vehicle, or other mechanical structure, are disclosed. A 3-D printer may be used to produce a tooling shell containing Invar and/or some other material for use in molding the panels. A channel may be formed in a 3-D printed tooling shell for enabling resin infusion, vacuum generation or heat transfer. Alternatively, or in addition to, one or more hollow sections may be formed within the 3-D printed tooling shell for reducing a weight of the shell.
US11154998B2 Dual sided razor
One embodiment of a dual sided razor comprises a handle and a cartridge attached to the handle, the cartridge further comprising a first shaving side and a second shaving side, the cartridge being switchable relative to the handle between the first and second shaving sides.
US11154996B2 Shaving unit having cutting units with a flush hole for cleaning a hair collection chamber
The invention relates to a shaving unit for a shaving apparatus The apparatus including at least a first cutting unit and a second cutting unit, where each of the first and second cutting units respectively include external cutting members having a plurality of hair entry openings and further respectively include internal cutting members which are rotatable relative the respective external cutting members about respective axes of rotation. The first and second internal cutting members being connected to a transmission unit via, respective first and second drive spindles. Each of the first and second cutting units including a housing having a bottom wall including an opening in fluid communication with a hair collection chamber in the housing. In each cutting unit opposed sealing surfaces are provided between the opening and the hair collection chamber, arranged to prevent cut hairs from escaping from the hair collection chamber via the opening and to allow water to flush via the opening to the hair collection chamber.
US11154994B2 Work device and dual-arm work device
A work device is configured to perform a work with use of an end effector and have six degrees of freedom. The work device including: a linear motion unit obtained by combining three linear motion actuators, to have three degrees of freedom; and a rotation unit obtained by combining a plurality of rotation mechanisms each having one or more degrees of rotational freedom, to have three degrees of freedom. A base portion of the linear motion unit is fixed to a mount. A base portion of the rotation unit is fixed to an output portion of the linear motion unit. The end effector is mounted to an output portion of the rotation unit.
US11154988B2 Robot hand, control method of robot hand, and robot apparatus
There is provided a robot hand that grips and positions a work with a certain gripping force, and that rapidly conveys the work to execute assembling after gripping the work.
US11154987B2 Robot
A robot includes a robot body including a base, a first movable section provided turnably with respect to the base, and a second movable section provided turnably with respect to the first movable section, a first proximity sensor for detecting contact with or approach of an object to the first movable section, and a second proximity sensor for detecting contact with or approach of the object to the second movable section. The first proximity sensor includes a first electrode section having a capacitance that changes according to the contact or approach of the object, and a first circuit section for detecting the capacitance of the first electrode section. The second proximity sensor includes a second electrode section having a capacitance that changes according to the contact or approach of the object, and a second circuit section for detecting the capacitance of the second electrode section.
US11154986B2 Local replanning of robot movements
Systems, methods, devices, and other techniques for planning and re-planning robot motions. The techniques can include obtaining a schedule that defines an execution order for a plurality of plans, each plan defining a sequence of tasks; providing instructions to the robotic system to execute plans from the plurality of plans according to the schedule; obtaining measurements for one or more parameters that represent a state of the robotic system or its environment that results from execution of at least one plan from the plurality of plans; determining, based on the measurements, that a particular plan from the plurality of plans, which has not completed execution, is to be revised; generating, using the measurements, a revised version of the particular plan; and adjusting the schedule so as to resolve a conflict between the revised version of the particular plan and at least one other plan in the plurality of plans.
US11154981B2 Robot user interface for telepresence robot system
A robot system that includes a remote control station and a robot that has a camera, a monitor and a microphone. The robot includes a user interface that allows a user to link the remote control station to access the robot. By way of example, the user interface may include a list of remote control stations that can be selected by a user at the robot site to link the robot to the selected control station. The user interface can display a connectivity prompt that allows a user at the robot site to grant access to the robot. The connectivity prompt is generated in response to a request for access by a remote control station. The robot may include a laser pointer and a button that allows a user at the robot site to turn the laser pointer on and off.
US11154979B2 Workbench
Embodiments of the invention provide a workbench, includes: a workbench unit (110), including a first workbench unit (112) and a second workbench unit (114), the first workbench unit (112) and the second workbench unit (114) are rotatably connected; the first table unit (112) is provided with a first working surface (1120), and the second workbench unit (114) is provided with a second working surface (1140); a bracket (120), including a plurality of support legs (122) and detachably connected to the workbench unit (110); when the workbench unit (110) is in the first state, the first working surface (1120) and the second working surface (1140) together form a working surface supporting the workpiece; when the workbench unit (110) is in the second state, the first workbench unit (112) and the second workbench unit (114) form a bracket placement cavity (140) for at least partially accommodating the bracket (120).
US11154977B2 Grip for a handheld instrument
A system, method, and apparatus may be provided for gripping a handheld instrument. A spherical body may be configured to support at least a portion of the handheld instrument. A working portion of the handheld instrument may be oriented below a body of the gripping device. A top opening may be provided at a top of the gripping device, wherein the top opening may be configured to receive a portion of the handheld instrument. A bottom opening at the bottom of the gripping device may be provided, wherein the bottom opening may be configured to receive a portion of the handheld instrument. A convex surface may receive a palmar surface of a user's fingers, thumb, and/or hand.
US11154973B2 Modular tool apparatus
A modular tool apparatus includes at least one handle, at least one utility tool, at least one attachment channel, at least one pivot pin, and at least one lever. The pivot pin includes a D-shaped cross section and rotatably connected to the handle thus enabling the foldable connection between the handle and the utility tool. The lever is terminally connected to the pivot pin and allows the pivot pin to be configured in between a locked position and an unlocked position. The attachment channel laterally traverses into the utility tool as the attachment channel is rotatably engaged around the pivot pin. The utility tool is foldably attached to the handle through the attachment channel and the pivot pin, wherein the D-shaped cross section of the pivot pin and a matching profile of the attachment channel allow the utility tool to be installed or removed from the pivot pin.
US11154972B2 Switch device for nail gun
A switch device for a nail gun includes a body having a main chamber and a cylinder is received in the main chamber. A main path communicates with the cylinder. A recess is formed in the body and a valve is received in the recess. An end member is connected to the rear end of the body. An air way communicates between the recess and the end member. A first release path communicates the recess and outside of the body. A communication path communicates between the main chamber and the recess. A switch member is located at the communication path. By operating the switch member, the features of single mode and automatic mode of the nail gun is controlled.
US11154970B2 Nail supply device for pneumatic nail gun
A nail supply device for pneumatic nail gun, including a piston seat, a longitudinal slideway, a transverse slideway connected to the longitudinal slideway, nail guide plates, and a slide clearance; the lower surface of the piston seat having a nail output interface; the upper surface of the piston seat having a nail inlet hole vertically connected to the nail output interface, the front side of nail inlet hole is connected to the rear side of longitudinal slideway; the front sidewall of the piston seat having a piston hole and a nail push hole adjacent to the piston hole, the nail push hole is connected to the longitudinal slideway. The nail supply device for pneumatic nail gun of the present invention can supply nails automatically when the pneumatic nail gun is nailing, the nailing efficiency and nailing quality are guaranteed effectively.
US11154964B2 Abrasive particles having particular shapes and methods of forming such particles
An abrasive article comprising a first group including a plurality of shaped abrasive particles overlying a backing, wherein the plurality of shaped abrasive particles of the first group define a first non-shadowing distribution relative to each other.
US11154963B2 Twist-lock assembly for a centrifugal blasting wheel
A twist-lock assembly for locking and unlocking a feed spout and control cage in their respective operative positions on a centrifugal blasting wheel. The twist-lock assembly includes a stationary control cage adapter and a rotatable clamping plate. The control cage adapter is mounted on a side wall of the centrifugal blasting wheel housing and located at an access opening in the housing. The clamping plate is rotatable with respect to the control cage adapter for locking and unlocking the control cage and the feed spout in their respective operative positions in response to rotation thereof between a clockwise locking position and a counterclockwise unlocking position. The result is an improved assembly for quickly dis-connecting and re-connecting the feed spout and control cage to provide ease of maintenance.
US11154961B2 Correction of fabricated shapes in additive manufacturing
A method of fabricating a polishing pad using an additive manufacturing system includes receiving data indicative of a desired shape of the polishing pad to be fabricated by droplet ejection. The desired shape defines a profile including a polishing surface and one or more grooves on the polishing pad. Data indicative of a modified pattern of dispensing feed material is generated to at least partially compensate for distortions of the profile caused by the additive manufacturing system, and a plurality of layers of the feed material are dispensed by droplet ejection in accordance to the modified pattern.
US11154956B2 Method of repairing turbine component using ultra-thin plate
Methods of manufacturing or repairing a turbine blade or vane are described. The airfoil portions of these turbine components are typically manufactured by casting in a ceramic mold, and a surface made up of the cast airfoil and at the least the ceramic core serves as a build surface for a subsequent process of additively manufacturing the tip portions. The build surface is created by removing a top portion of the airfoil and the core, or by placing an ultra-thin shim on top of the airfoil and the core. The overhang projected by the shim is subsequently removed. These methods are not limited to turbine engine applications, but can be applied to any metallic object that can benefit from casting and additive manufacturing processes. The present disclosure also relates to finished and intermediate products prepared by these methods.
US11154950B2 Method for creating a welded steel part with uniform microstructure
A method for creating a welded steel part includes providing a first steel plate having a first base, a first intermetallic alloy layer on the first base and a first metal alloy layer on the first intermetallic alloy layer; providing a second steel plate having a second base, a second intermetallic alloy layer on the second base and a second metal alloy layer on the second intermetallic alloy layer; butt welding the first and second steel plates at a weld so as to melt material from at least the first base, the first intermetallic alloy layer, the second base and the second intermetallic layer to form a molten weld material; austenizing the welded steel plates at a temperature between Ac1 and Ac3+100 degrees C. for a time greater than or equal to 20 seconds; and cooling the welded steel plates so as to render a uniform microstructure to the weld.
US11154949B2 System, apparatus and method for hybrid function micro welding
An apparatus, system and method for micro welding, wherein insulated object, such as a wire, that includes a metallic conductor that is at least partially covered by one or more layers of insulation, is positioned across a termination point. A laser beam may be applied to an area of the insulated object overlapping the termination point, wherein the applied laser beam is configured to substantially simultaneously (i) ablate the one or more layers of insulation in a first region of the area, (ii) weld the metallic conductor to the termination point in a second region of the area, and (iii) detach a portion of the object from the termination point in a third region of the area.
US11154948B2 Laser beam machining device and a process of laser machining comprising a single lens for light focussing
A laser beam machining device (1) is provided, in which unfocused light (A) from a light exit point (B) is radiated onto a single lens (8), where in the lens (8) focuses the laser light (A) and guides it onto a machining point of a work piece (7). A distance (ma, mb) between the lens (8) and the light exit point (B) and a distance (la, lb) between the lens (8) and the machining point of the workpiece (7) and a distance between the light exit point (B) and the aforementioned machining point can be varied. Moreover, a process of usage of a laser beam machining device (1) is provided.
US11154947B2 Laser processing system
There is provided a laser processing system including: a robot; a laser emission section provided on the robot; an irradiation path calculation section configured to calculate an irradiation path of a laser beam emitted from the laser emission section using information on a position of the robot; a determination section configured to determine whether the irradiation path calculated passes through an allowable irradiation region that is predetermined; and a laser-output reduction section configured to reduce output of the laser beam to be emitted to the irradiation path to a second output lower than a first output for processing in accordance with a determination by the determination section that the irradiation path does not pass through the allowable irradiation region.
US11154946B2 Systems and methods for the control of welding parameters
A welding system includes a welding torch, a power supply, one or more sensors, and a controller is provided. The welding torch advances an electrode toward a workpiece in a first direction. The power supply provides a flow of electricity to the electrode for generating a welding arc between the electrode and the workpiece. Generating the welding arc generates a weld puddle behind the welding arc as the electrode moves in the first direction. The sensor generates a voltage output signal based on the amount of light received from the weld puddle. The controller is communicatively coupled with the sensor to receive the voltage output signal, and the sensor controls a welding parameter of the welding system based the voltage output signal.
US11154945B2 Method for producing a gas-tight metal-ceramic join and use of the gas-tight metal-ceramic join
A method for producing a gas-tight metal-ceramic join is disclosed. In an embodiment a method includes providing at least one ceramic main body having a first end face and a second end face, applying a metallization to at least a partial region of the end faces of the main body, applying a nickel layer to the metallized partial region of the end faces, applying a brazing paste to the metallized partial region of the first end face and/or the second end face of the main body, drying the brazing paste, and firing the brazing paste.
US11154944B2 Blade with removable working surfaces and methods of making and using
Tools are described having removable working elements, include saws having removable cutting elements. Interface geometries on one or more of a core structure and removable elements may be simple or complex geometries. Securement elements releasably hold the removable elements in place.
US11154943B2 Chainsaw
Disclosed is a chainsaw capable of making it less likely that vibrations due to driving of an electric motor and a endless movement of a saw chain are transmitted to a worker, thereby enabling the worker to become less likely to be fatigued even in work using the chainsaw. The chainsaw includes an electric motor provided inside a body casing; a guide bar provided in a front portion of the body casing in such a manner as to protrude forwardly; a saw chain provided around an outer periphery of the guide bar in an endlessly movable manner, and configured to be endlessly moved along the outer periphery of the guide bar under driving of the electric motor; a handle section provided with respect to the body casing, and configured to be gripped by a worker; and an anti-vibration member interposed between the body casing and the handle section.
US11154940B2 Hole saw arbor assembly
A cutting tool includes a hole saw, a pilot bit, and an arbor assembly. The arbor assembly includes a shank, a sleeve, a first ball bearing moveable relative to the shank, the first ball bearing engaging the hole saw to releasably secure the hole saw to the shank, and a second ball bearing moveable relative to the shank, the second ball bearing engaging the pilot bit to releasably secure the pilot bit to the shank. The sleeve is moveable to a first position where the hole saw and the pilot bit are secured to the arbor assembly, to a second position where the first ball bearing disengages the hole saw, allowing removal of the hole saw from the shank, and to a third position where the second ball bearing disengages the pilot bit, allowing removal of the pilot bit from the shank.
US11154937B2 Tool holder
A tool holder includes a tubular body having a shank on a first axial end portion, a tool gripping portion on a second axial end portion, and an elastic segment interposed between the shank and the tool gripping portion in the axial direction of the body. The elastic segment is more elastically deformable along the axial direction and around a circumferential direction of the tubular body than the shank and the tool gripping portion owing to a plurality of voids that extend through the elastic segment from an outer peripheral side of the tubular body to an inner peripheral side of the tubular body. Each of the voids includes segments that extend around the circumferential direction and along the axial direction of the tubular body.
US11154934B2 Build material application device
Build material application device (5) for an apparatus (1) for additively manufacturing at least one three-dimensional object (2) by means of successive layerwise selective irradiation and consolidation of layers of build material (3) which can be consolidated by means of at least one energy beam (4), the build material application device (5) comprising: —at least one build material application element (8) configured to apply an amount of build material (3) in a build plane (E) of a respective apparatus (1) for additively manufacturing at least one three-dimensional object (2); —at least one spatter removal element (9) configured to remove spatters (10) present in a layer of build material (3) of a respective apparatus (1) for additively manufacturing a three-dimensional object (2), particularly to remove spatters (10) originating from a selective irradiation of the respective layer of build material (3).
US11154933B2 Three-dimensional shaped article production method, three-dimensional shaped article production apparatus, and three-dimensional shaped article
A three-dimensional shaped article production method according to the invention is a method for producing a three-dimensional shaped article by stacking layers formed in a predetermined pattern, wherein a series of steps including a composition supply step of supplying a composition containing a plurality of particles to a predetermined part, and a bonding step of bonding the particles by irradiation with a laser light is performed repeatedly, and the composition supply step includes a step of forming a first region using a first composition containing first particles as the composition, and a step of forming a second region using a second composition containing second particles which are different from the first particles as the composition, and the bonding of the particles in the first region and the bonding of the particles in the second region are performed by irradiation with laser lights with a different spectrum.
US11154930B2 Method for producing a porous shaped body
A method for producing a porous shaped body may include providing a mixture of a powder including at least one of a metal, a metal alloy, and a ceramic, with a resin/activator mixture. The method may then include introducing the mixture by core shooting into a cavity formed in a forming tool, and solidifying the mixture in the forming tool to give a shaped body. The method may then include heating the shaped body to remove at least one of organic constituents and gases present in the shaped body. The method may further include resolidifying the shaped body by a sintering operation.
US11154917B2 Pig pumping unit
A pig pumping unit is provided that allows eight passes to be made simultaneously with a single pumping unit. A single engine is used to drive three or four pumps, each connected into separate pumping units. Two engines may thus be used to drive up to eight pumps in a single trailer.
US11154916B2 Method for cleaning a solder nozzle of a soldering system
The invention relates to a method for operating a soldering system for selective wave soldering comprising at least one solder crucible, the solder crucible comprising a solder reservoir, a solder nozzle and a solder pump, the solder pump being designed to guide the liquid solder out from the solder reservoir through the solder nozzle for generating a standing wave from liquid solder. The invention relates, in particular, to a method for cleaning a solder nozzle comprising the following steps: conveying solder from the solder reservoir at a first pump capacity which is adjusted in such a way that a standing wave of liquid solder is generated at a solder level which is below an upper edge of the nozzle outlet of the solder nozzle; introducing a cleaning agent into the nozzle outlet of the solder nozzle; increasing the pumping capacity of the solder pump to a second pump capacity such that the cleaning agent flows over the upper edge of the nozzle such that the cleaning agent is guided to an outer side of the solder nozzle.
US11154915B2 Pine straw cleaning machine
A machine for removing debris from pine straw is described. The machine comprises a conveyor system, a doffer, a debris-pine straw separation zone, and a clean pine straw zone. The conveyor system and doffer thin, spread and fluff the pine straw, as well as control the flow of pine straw to the separation zone. A system of air is directed through the separation zone and engages pine straw and debris discharged into the separation zone and effectively separates the debris from the pine straw, after which the pine straw is directed from the separation zone to the clean pine straw zone.
US11154912B2 Denuder
A denuder, such as a bone stock denuder container, is disclosed. The denuder includes a nozzle and a container body. The nozzle is configured to be fluidically coupled to a source of fluid and to direct a fluid stream. The container body includes curved chamber wall that forms a wash chamber. The wash chamber is configured to receive a bone stock. The nozzle is configured to direct the fluid stream to impact the curved chamber wall.
US11154909B2 Electric brush for sand removal
A foldable, compact electric brush for removing dirt and sand from a body including a brush, a handle with at least one handle extension; a tubular component with two swivel joints on opposite sides for attaching the brush and handle extension; a motor to turn the brush; a rechargeable power source and a power button to power on and off.
US11154906B2 Receive operation of an ultrasonic sensor
An ultrasonic sensor includes a two-dimensional array of ultrasonic transducers including a plurality of sub-arrays of ultrasonic transducers, wherein a sub-array of ultrasonic transducers of the plurality of sub-arrays of ultrasonic transducers is independently controllable, and wherein a sub-array of ultrasonic transducers has an associated receive channel. A plurality of shift registers is configured to select a receive pattern of ultrasonic transducers of the two-dimensional array of ultrasonic transducers to activate during a receive operation. An array controller is configured to control selection of the ultrasonic transducers during the receive operation according to the receive pattern and configured to shift a position of the receive pattern within the plurality of shift registers such that the ultrasonic transducers activated during the receive operation moves relative to and within the two-dimensional array of ultrasonic transducers.
US11154903B2 Apparatus and method for surface coating by means of grid control and plasma-initiated gas-phase polymerization
An apparatus and a method for surface coating by means of grid control and plasma-initiated gas-phase polymerization. The method comprises: dividing a vacuum chamber into a discharging cavity (2) and a processing chamber (3) by using a metal grid mesh (1), the metal grid mesh (1) being insulated from the vacuum chamber; separately feeding carrier gas and monomer steam into the discharging cavity (2) and the processing chamber (3) through different pipes (4, 5), putting a substrate to be processed (11) in the processing chamber (3), and generating in the discharging cavity (2) plasma that continuously discharges; and applying pulse positive bias to the metal grid mesh (1), to release the plasma into the processing chamber (3) to initiate monomer polymerization.
US11154902B2 Transparent conductive substrate and method for producing same
To provide: a transparent conductive substrate containing silver nanowires and having excellent optical characteristics, electrical characteristics and light resistance; and a method for producing the same. A transparent conductive substrate characterized by comprising: a substrate; a transparent conductive film formed on at least one principal surface of the substrate, and containing a binder resin and conductive fibers; and a protective film formed on the transparent conductive film, wherein the thermal decomposition starting temperature of the binder resin is 210° C. or higher, and the protective film is a thermal-cured film obtained using a thermosetting resin.
US11154900B2 Display apparatus and manufacturing method thereof
A display device according to one or more exemplary embodiments of the present invention includes: a display panel; a window on the display panel; an active surface layer on the window; and a hard coating layer on the active surface layer and having a curved surface.
US11154892B2 Coating device for applying coating agent in a controlled manner
The disclosure concerns a coating device for coating components with a coating agent, in particular for painting motor vehicle body components with a paint, with a printhead for applying the coating agent to the component, and with a coating agent supply for supplying the printhead with the coating agent to be applied, wherein the coating agent flows from the coating agent supply to the printhead at a specific coating agent pressure and a specific flow rate. The disclosure provides that the coating supply will control the coating agent pressure and/or the flow rate of the coating agent. Furthermore, the disclosure includes an associated operating method.
US11154891B2 Using an accumulator to improve delivery of liquid through a valve on an agricultural machine
An accumulator is added in-line with a valve on an agricultural machine and downstream of the valve. The valve is controlled to apply liquid material to a field over which the machine is traveling.
US11154886B2 Metered and active sprayer devices with aerosol functionality (“Flairosol II”)
In exemplary embodiments of the present invention, “Flairosol” dispensing devices can be provided. Such devices utilize a combination of Flair® technology, pre-compression valves and aerosol-like pressurization of the dispensed liquid. Such a dispensing device has, for example, a main body comprising a pressure chamber, the latter being provided with a pressure piston and a pressure spring. The device further has a piston and a piston chamber which draws liquid from a container, for example, the inner container of a Flair® bottle, and fills the pressure chamber with that liquid as a user operates a trigger in various compression and release strokes. The piston chamber has both an inlet valve and an outlet valve, which serve to prevent backflow. Liquid exiting the piston chamber under pressure (supplied by, a user pumping the trigger) enters a central vertical channel which is in fluid communication with both the pressure chamber (above the pressure piston) and a dome valve provided near the outlet channel at the top of the dispensing head. The dome valve has a preset pressure, such that once exceeded by the liquid, opens and allows for a spray. If the liquid pressure drops below such preset pressure, the dome valve closes off the outlet channel, which serves to regulate the strength of the flow and preclude leakage. Alternatively, in an activated embodiment, for example, once the liquid is sufficiently pressurized, it can be dispensed by a user allowing the dome valve to open by pressing on an activation button that removes a dome lock.
US11154882B2 Cage design with modified struts including oriented fins
A sprinkler body for a rotating sprinkler includes a base securable to a source of water under pressure, a plurality of support struts connected to and extending from the base, and a deflector plate support connected to the plurality of support struts and disposed spaced from the base by the support struts. At least one of the plurality of support struts is wedge-shaped with an inward-facing apex. The support struts are configured to create a void in the water spray pattern away from a center pivot pipe and to direct the water spray downward to limit the effect of wind on the spray pattern.
US11154881B2 Rotary nozzle
An irrigation nozzle with a rotating deflector is provided whose rotational speed may be controlled by a friction brake. The nozzle may also include an arc adjustment valve having two portions that helically engage each other to define an opening that may be adjusted at the top of the sprinkler to a desired arcuate length. The arcuate length may be adjusted by pressing down and rotating a deflector to directly actuate the valve. The nozzle may also include a radius reduction valve that may be adjusted by actuation of an outer wall of the nozzle. Rotation of the outer wall causes a flow control member to move axially to or away from an inlet.
US11154877B2 Rotary strip nozzles
A specialty nozzle is provided having a pattern adjustment valve that may be adjusted to irrigate a substantially rectangular irrigation area. The nozzle may be further adjusted to irrigate three different substantially rectangular irrigation areas. The nozzle is adjustable to function as a left strip nozzle, right strip nozzle, and side strip nozzle. The strip irrigation setting may be selected by pressing down and rotating a deflector to directly actuate the valve. The nozzle may also include a flow reduction valve to set the size of the rectangular irrigation areas and may be adjusted by actuation of an outer wall of the nozzle. Other specialty nozzles are provided having a fixed pattern template to irrigate a rectangular area, such as left strip, right strip, or side strip.
US11154875B2 Pulsating device with two preset pressure-responding normally closed valves
A pulsating device with two preset pressure-responding normally-closed valves is disclosed. The first valve is used for accumulating fluid. The second valve is used for creating resistance so as to force the first valve to open widely. The second valve may be configured so it creates little to no resistance once opened. In some embodiments, the pulsating device converts a low controlled and/or continuous flow of fluid, such as water and/or air, to a high pulsating and/or intermittent flow. A pulsating device may operate, for example, one or more drip lines, pop ups, sprinklers, misters and/or other irrigation devices.
US11154870B2 Method for grinding silicon-containing solids
The object of the invention are methods for the production of silicon particles by grinding silicon-containing solids in a jet mill using a grinding fluid containing water vapor.
US11154869B2 Device for pulverization and explosion suppression of low carbon gas hydrate
The present invention discloses a device for pulverization and explosion suppression of low carbon gas hydrate (LCGH). A feeding chamber connects with a pulverizing chamber, and the chambers communicate through a feed port. A pulverizing air pipe and the feeding chamber communicate through a feeding air pipe; two ends of a venturi connect with an entrainment chamber and a disperser respectively; and a gas-solid separation membrane (GSSM) is disposed on a discharging port and used for preventing LCGH powder from entering the entrainment chamber from the pulverizing chamber. When an explosion is triggered, the GSSM is opened to make the LCGH powder enter the entrainment chamber. The device can store and pulverize the LCGH and spray LCGH powder to achieve combustion and explosion suppression.
US11154866B2 Systems and methods for facilitating fluid flow during enhanced detection and quantification of analytes
Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.
US11154864B2 Microfluidic device with vented microchambers
A microfluidic device with a microfluidic circuit including an array of fluidly coupled microchambers. Each microchamber includes a reaction chamber and an associated vent chamber. The microfluidic circuit may be arranged so that a fluid sample introduced to microfluidic device flows into the reaction chamber and air or other gas present in the reaction chamber is vented from the microchamber through the vent chamber. The microchamber may be configured to allow only the flow of air into the vent chamber from the reaction chamber until the air has been displaced from the reaction chamber by the fluid sample and/or a predefined volume of the fluid sample has been received in the reaction chamber. The microchamber may be further configured to release the fluid sample to thereafter flow from the reaction chamber into the vent chamber.
US11154863B2 Systems and methods for optically processing samples
A system for processing a sample includes a chamber having at least one inlet and at least one outlet, where the chamber is configured to accommodate flow of the sample from the at least one inlet toward the at least one outlet, and an imager array configured to image the flow of the sample in the chamber, where the imager array includes at least one lensless image sensor configurable opposite at least one light source.
US11154862B2 Methods for using multi-sheath flow and on-chip terminating electrode for microfluidic direct-blotting
Devices and methods are provided for the separation and dispensing of material using a microfluidic separation column connected via an exit channel to one or more sheath flow channels. The flow of separated material through the separation column is at least partially driven by a voltage potential between a first electrode within the separation column and a terminating electrode within at least one of the sheath flow channels. The separation column, exit channel, sheath flow channels, and electrodes are all within a single monolithic chip. The presence of an on-chip terminating electrode allows for separated material to be entrained in the sheath fluids and ejected onto a surface that can be non-conductive. The presence of multiple sheath flows allows for sheath flow fluids to have different compositions from one another, while reducing the occurrence of sheath flow fluids entering the separation column.
US11154858B2 Microfluidic tissue development systems
Disclosed herein are various bioreactor devices and systems for growing cellular material, and related methods of growing cellular material. In some cases, a system can include a bioreactor system having one or more wells with at least one fluidic passageway coupled to each well to feed fluids to biological material being developed inside the well. In some cases, a bioreactor system can include a main body comprising the perimeter of the well and the fluidic passageways, a cover that forms the top of the well and provides optical access into the well, and a base that forms the bottom surface of the well. The cover and base can be attached and detached from the main body to seal the well closed and to physically access the contents of the well.
US11154856B2 Test device
A test device includes a housing and a lid. The housing encloses an internal space, has a hole supporting a container accommodating liquid, and includes a perforation/incision part. The lid covers a hole-formed part of the housing. The housing and/or the lid includes a guide that guides the housing and the lid, so that the lid can migrate from the first position to the second position while covering the hole-formed part of the housing. In the first position, the lid covers the hole-formed part of the housing and the container and the container is not incised. During the migration of the lid from the first position to the second position, the container is pushed toward the perforation/incision part by the lid, and the container is incised to leak liquid into the internal space.
US11154853B2 Generation of data for use with antimicrobials
An assay is performed so as to identify a pathogen in a sample taken from a patient. The identity of the pathogen in the patient sample is used to select an antimicrobial for treatment of the patient. The antimicrobial can be selected in less than 7 hours after the patient sample is taken from the patient. For instance, when the sample is blood, the antimicrobial can be selected in less than 7 hours after the patient sample is taken from the patient. When the sample is urine, the antimicrobial can be selected in less than 4 hours after the patient sample is taken from the patient.
US11154850B2 Cr6 reduction in fluidized bed
Disclosed is a process for the manufacture of a chromium-containing catalyst with a reduced amount of chromium-(VI)-oxide which process comprises the steps: a) preparing a solid particulate chromium-containing oxidic catalyst comprising Cr-(VD-oxide, b) introducing the solid particulate catalyst into a reactor in which the catalyst particles are mixed using process gas and/or mechanical means, c) introducing a reducing agent for chromium-(VI) into the reactor, d) treating the solid particulate catalyst with the reducing agent in the reactor for a time, at a temperature and at a pressure, so that the chromium-(VI) content in the particulate catalyst is considerably reduced by the reducing agent, and e) discharging the solid particulate catalyst comprising a reduced chromium-(VI) content from the reactor. The disclosed process is simple and efficient and allows manufacture of chromium-containing oxidic catalysts with low content of Cr-(VI)-oxide on an industrial scale.
US11154849B2 Method of manufacturing a honeycomb metal structure using aluminum powder
A method of manufacturing a honeycomb metal structure includes providing a substrate comprising iron (Fe) and a container containing water; coating at least a part of the substrate with a viscid material whose viscidity is increased by moisture; attaching metal powder onto the viscid material; adhering the metal powder to the substrate due to an increase in viscidity of the viscid material by evaporating a portion of the water in the container and supplying moisture to the viscid material; and generating an uneven structure made of the metal powder bonded to the substrate by performing a heat treatment on the substrate to which the metal powder is adhered. The heat treatment may include performing a first heat treatment on the substrate to generate an intermetallic layer at an interface between the substrate and the metal powder; and performing a second heat treatment to dissolve the intermetallic compound layer.
US11154844B2 Cobalt carbide-based catalyst for direct preparation of olefin from synthesis gas, preparation method therefor and application thereof
A cobalt carbide-based catalyst for direct production of olefin from synthesis gas, a preparation method therefor and application thereof are disclosed. The method for preparing the catalyst comprises the following steps: 1) mixing a cobalt source with water, or mixing a cobalt source, an electron promoter and water to obtain a first solution; and mixing a precipitant with water to obtain a second solution; 2) adding the first solution and the second solution to water, or water and a structure promoter for precipitation, crystallizing, separating, drying and calcination; and 3) reducing a solid obtained in Step 2) in a reducing atmosphere, and then carbonizing in a carbonizing atmosphere. The prepared catalyst has high activity and high selectivity to olefins for direct production of olefins via syngas conversion.
US11154843B1 Methods of forming nano-catalyst material for fabrication of anchored nanostructure materials
Methods of producing a nano-catalyst material including forming a plurality of nano-scale features on a surface of a substrate material. The nano-catalyst material may be used for forming anchored nanostructure materials by heating the nano-catalyst material under a protective atmosphere to a temperature ranging from about 450° C. to about 1500° C. and exposing the heated nano-catalyst to an organic vapor to affix a separate nanostructure to each of the plurality of nano-scale features. The nano-scale features may be formed on the surface of the substrate material by mechanical or thermal processes.
US11154842B2 Exhaust gas purification underfloor catalyst and catalyst system
An exhaust gas purification underfloor catalyst characterized in having a catalyst layer having a lower layer and an upper layer, the lower layer containing alumina and CeO2, the noble metal content of the lower layer being at most 0.5 mass % in relation to the mass of the lower layer, the upper layer containing Rh, alumina, and CeO2, the amount of noble metals other than Rh contained being 1 mol % or less in relation to the total amount of noble metals contained in the upper layer, the total amount of CeO2 contained in the lower layer and the upper layer being 14 g/L to 30 g/L, the amount of CeO2 contained in the upper layer being 7 g/L to 25 g/L, and the amount of CeO2 contained in the lower layer being 20% or more of the amount of CeO2 contained in the upper layer.
US11154832B2 Fluidizing plate and apparatus comprising such a fluidizing plate
The invention relates to a fluidizing plate, comprising a supporting structure and plate segments, the plate segments respectively having openings through which gas flows during operation. The plate segments are respectively releasably connected to the supporting structure and two neighboring plate segments respectively overlap and are releasably connected to one another in the region of the overlap. The invention also relates to an apparatus with such a fluidizing plate.
US11154830B2 Device for limiting entrainment of solid particles at the outlet from a three-phase fluidized bed
The present invention concerns a device for limiting the entrainment of solid particles placed inside a three-phase fluidized reactor, said device being constituted by an assembly of flat or truncated cone-shaped plates ranked vertically in one or more rows, and the maximum horizontal cross section area of the device being in the range 1 to 10 times the horizontal cross section area of the outlet pipework for the gas effluents. It also concerns a three-phase process employing said device.
US11154829B2 Method and metering device for metering a liquid or pasty product in a pressure-regulated manner
A method for metering a liquid or pasty product in a pressure-regulated manner, has the following steps: metering the product into a mixing chamber using a metering pump; ascertaining a product pressure of the product according to the mixing chamber; ascertaining a deviation of the product pressure from a specified target pressure; and opening or closing a pressure regulating valve provided on an outlet nozzle of the mixing chamber based on the pressure in order to equalize the product pressure and the target pressure, wherein the product pressure is reduced when the pressure regulating valve is opened and increased when the pressure regulating valve is closed.
US11154825B2 Enhanced micro bubble device, system and methods related thereto
Systems and methods for enhanced filtration and separation of fluid from microorganisms, toxins and other particles in a more efficient manner is provided. The system may include a selectively removeable fitting or replaceable filter media and is suitable for use with liquid dispensing devices such as hydrotherapy jets, shower heads, liquid nozzles, and bathtub faucets.
US11154821B2 Nanofiber containing composite membrane structures
A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.
US11154819B2 Anti-fouling chiral surfaces for membrane filtration and methods therefor
The present disclosure relates to, inter alia, a modified surface comprising an optically active monomer, a polymeric material having a surface onto which the optically active monomer is covalently bound. In one aspect, a membrane comprising an optically active monomer, a poly(aryl sulfone) membrane having a surface onto which the optically active monomer is covalently bound. The present disclosure also relates to a method of modifying a surface, the method comprising applying sufficient energy to a surface to induce covalent bonding with an optically active monomer, and contacting the optically active monomer with the surface. In one aspect, a method of modifying a surface of a poly(aryl sulfone) membrane is disclosed. In another aspect, a method of synthesizing an optically active monomer is disclosed. In one aspect, a method of filtration of chiral compounds is disclosed.
US11154818B2 Tubular membrane with spiral flow
A permeable membrane tube to separate mixed fluids is provided, including a cyclone generator configured to cause fluid entering the permeable tube to flow in a spiral direction. The cyclonic generator may be a plug positioned at the fluid entrance of the membrane tube. The fluid passes through the permeable membrane tube, which has a center axis along a length of the tube, and flows in the spiral direction thereby separating the fluid into first and second portions, wherein the first portion comprises fluid having a greater density than the second portion and the first portion is directed to an inner surface of the tube.
US11154817B2 Formed sheet membrane element and filtration system
A piece of substrate material is formed under heat and pressure by a roller against a cavity or platen into a shaped substrate sheet having one or more depressions. Two substrate sheets are bonded together to form a substrate wherein the one or more depressions form one or more interior channels. The substrate is coated with a dope in a casting device having a guide portion corresponding to the shape of the substrate sheets and quenched to form a filtering membrane.
US11154807B2 Fan scrubber and controlling method of fan scrubber
According to one embodiment, a fan scrubber includes an inlet pipe to be connected to a post-stage side of a vacuum pump, in a state where a film preparation apparatus is arranged at a pre-stage before the vacuum pump, a process chamber connected to the inlet pipe, and containing a fan connected to a main shaft of a motor, a heater configured to heat the inlet pipe, and a controller configured to control turning on/off of the heater. The controller turns off the heater, when a signal received from the film preparation apparatus has been switched from a film preparation signal to a cleaning signal.
US11154806B2 Method for controlling filtering efficiency of a filter for an exhaust aftertreatment system
A method for controlling a filtering efficiency of a filter including a filtering area between an inflow area and an outflow area. Determining a present exhaust mass flow into the filter. Determining a pressure drop across the filter from the inflow area and the outflow area of the filter. Normalizing the measured pressure drop to provide a normalized pressure drop according to a predetermined normalization pressure level at a predetermined temperature for a model filter. Comparing the normalized pressure drop to a pressure drop model including a relation between the pressure drop across a filter and exhaust mass flow to the filter. Determining a pressure deviation between the normalized pressure drop and a pressure drop value calculated based on the pressure drop model and the present exhaust gas flow. Controlling the pressure drop across the filter for reducing the pressure deviation.
US11154804B2 Water extractors and methods of making water extractors
A water extractor for an environmental control system includes a primary duct having an inlet and an outlet, a scupper with a scupper inlet extending about the inlet of the primary duct, and a supply duct. The supply duct is in fluid communication with the primary duct and has a wall with an interior surface terminating at the scupper inlet. The interior surface defines one or more one swirl groove within the wall for gathering and conveying liquid water entrained in an airflow traversing the inlet duct to the scupper inlet. Environmental control systems, methods of making water extractors, and methods of removing water from air flows are also described.
US11154794B2 Sampling pumps and closed loop control of sampling pumps to load traps
Certain configurations of devices and systems which are configured to draw a selected volume of an air sample into a trap are described. In some examples, the devices and systems comprise a pump and a mass flow sensor to draw a selected volume of the air sample through a trap even where variable restriction occurs.
US11154792B2 Methods and systems for generating process gases
Methods for the gas-phase delivery of gases, such as process gases, from the gas phase of a multicomponent source liquid are provided. The methods are generally directed to the generation of process gases having mass flow rates which are proportional to the input power delivered to the multicomponent source liquid containers. The methods may be used to deliver process gases to critical process applications.
US11154786B2 Systems and methods for a network-based video game application
Embodiments of the systems and methods disclosed herein provide a game that includes at least two users that each have a preconfigured set of playable virtual entities. The users draw playable virtual entities from each of their respective sets of playable virtual entities, and can play the playable virtual entities in one or more battles to facilitate moving a virtual positional marker towards a goal or shooting a goal, wherein the battle procedures are based on a turn priority. Certain attributes are associated with the playable virtual entities so that playable virtual entity effects, OVR values, and salary values can affect which playable virtual entities are in a deck and how the playable virtual entities are affected by the location of the virtual positional marker and/or other playable virtual entities.
US11154783B1 Systems and methods for player-initiated proof of in-game participation by unique digital articles
Systems and methods to support player-initiated proof of in-game participation by unique digital articles in in-game events are disclosed. Exemplary implementations may execute instances of a game; manage player accounts associated with the players; record usage information pertaining to player-owned unique digital articles on a permanent registry; present a player interface for a player to select an in-game event; store video information of the selected in-game event; and record references to the stored video information on the permanent registry such that the video information is accessible for viewing by users of the permanent registry.
US11154781B2 Game device, game method and game program
A game device for reducing the processing load of a redraw process, including a storage module storing game content information associated with identification information for one or more users, and a module for processing a lottery, in which multiple types of game contents may each be associated with an index value corresponding to the relative values of the types of game contents. The module for processing the lottery may include a module for executing redrawing that may execute new lottery processing for drawing, via the lottery, a type of game content that differs from game content drawn by a first lottery process, when the game content drawn by the first lottery process related to one user's identification information is associated with an index value which is equal to or greater than a predetermined standard value, and when said game content has a predetermined relationship with the game content information related to the user's identification information.
US11154776B2 Semantic gaming and application transformation
A gaming system comprises a handheld user input device, a processor for receiving input data from the handheld user input device and a gaming application for receiving data from the processor based on the received input data from the handheld user input device. The handheld user input device emulates one of a plurality of different devices associated with the gaming application. Each of the plurality of different devices have a set of input commands associated therewith. The set of input commands associated with the one of a plurality of different devices includes a command based on one of motion and orientation of the handheld device.
US11154775B2 Synchronized gaming and programming
To encourage viewer participation, games, contests and social interactions are able to be synchronized with programming such as television shows or commercials utilizing a second screen such as a cell phone, iPad® or laptop computer. The programming is able to be television programming, Internet programming (e.g. a video displayed on a webpage or mobile device) or any other programming. The gaming is able to be any game such as a game of skill or chance, for example, a scavenger hunt or a treasure hunt.
US11154773B2 Game event recognition
A game-agnostic event detector can be used to automatically identify game events. Game-specific configuration data can be used to specify types of pre-processing to be performed on media for a game session, as well as types of detectors to be used to detect events for the game. Event data for detected events can be written to an event log in a form that is both human- and process-readable. The event data can be used for various purposes, such as to generate highlight videos or provide player performance feedback.
US11154772B2 Handheld controller grip attachment
Embodiments of the present disclosure include a grip attachment that changes the shape of a handheld controller, allowing individual users to comfortably hold the controller while they interact with the controlled system. For example, some embodiments include a video game controller grip attachment having features that conform to fit securely with the video game controller, allow the user to hold the video game controller, and/or enable a user to grip a handheld controller in different configurations. In other embodiments, the grip for interfacing with one hand (e.g., the right hand) may be different than the grip for interfacing with the other hand (e.g., the left hand). In some embodiments, the grip has a palm swell element including a controller interface surface configured to at least partially accommodate a back surface of a handheld controller, and/or an outer surface extending an overall depth of the palm area of the handheld controller.
US11154766B2 Tracked personal snow transport system
The present disclosure provides a snow transport system with a frame comprising a base plate, a pair of opposed side plates mounted on opposed sides of the base plate, and a plurality of cross members extending between the side plates. A pair of convex lower track slides are mounted on lower portions of the pair of opposed side plates, and a pair of convex upper track slides are mounted on upper portions of the pair of opposed side plates. A drive wheel is mounted at an upper front portion of the frame, and an idler wheel mounted at a lower rear portion of the frame. A continuous track is wrapped around the drive wheel, the convex lower track slides, the idler wheel and the convex upper track slides. A motor assembly is mounted within the frame, and connected to the drive wheel through a transmission assembly. A push arm assembly is mounted to one side of the frame, the push arm assembly extending forwardly from the frame and having a push bar portion and user controls at a forward end thereof.
US11154764B2 Brake device
A brake device for a sliding board, including: a base for connecting the brake device to the sliding board; and a brake, including: at least one brake paddle; a latching element which can be moved back and forth between a first position in which the brake paddle can be released in order to slow the sliding board and a second position in which the brake paddle can be fixed in a non-braking position; and a pedal which includes a bearing area for a boot and a functional element which can be moved relative to the bearing area, wherein moving the functional element releases the latching element to be moved from the first position to the second position.
US11154758B2 Pocket stabilizer for lacrosse head
A pocket stabilizer for maintaining the spacing between the sidewalls of a lacrosse rim, comprising: a pair of ears each including an upper helix, a lower lobe and a medial segment disposed therebetween. The upper helix of the pair define a first dimension corresponding to a first sidewall spacing and the lower lobes of the pair define a second dimension corresponding to a second sidewall spacing. A stabilizing member is disposed between and integrates the medial segments of the pair of ears. The pocket stabilizer is placed within the pocket of the lacrosse head and slid downwardly into the throat such that the lower lobes and medial segments are wedged between the sidewalls of the lacrosse head rim to retain the shape of the rim and prevent plastic deformation thereof while the lacrosse head is not in use.
US11154750B2 Motor assisted split-crank pedaling device
Split-crank pedaling devices and methods of operation support patient use and rehabilitation, particularly for stroke patients. A split-crank pedaling device includes first and second crank assemblies. First and second motors are operably connected to the first and second crank assemblies. A first shaft sensor produces an indication of a position of the shaft of the first crank assembly. A second shaft sensor produces an indication of a position of the shaft of the second crank assembly. A controller is communicatively connected to the first and second motors and the first and second shaft sensors and calculates a phase error between the positions of the first and second shafts and a predetermined phase relationship between the first and second shafts. The controller operates at least one of the first motor or the second motor to provide a supplemental torque to one of the first crank assembly and the second crank assembly.
US11154748B2 Elliptical trainer
An embodiment of the present invention provides an elliptical trainer including structures featuring a first amplitude, a second amplitude, and a third amplitude. By the driving of cranks and the combination of the three amplitudes, the elliptical trainer's pedals move along a closed ellipse path. In addition, the first amplitude is more than twice or three times of the third amplitude, resulting in a wide adjustment range of the stride of the pedal. Accordingly, the elliptical trainer is applicable to users of various heights.
US11154743B2 Weight delay device for weight training equipment
A weight delay device for weight training equipment includes a delay member vertically movable between a second top dead point and a second bottom dead point, and a locking assembly vertically movable with the main weight device of the weight training equipment and having a positioning member selectively locatable at a first position or a second position. When the positioning member is located at the second position and the main weight device starts to move from the first bottom dead point to the first top dead point, the positioning member and the delay member are combined with each other, so that the delay member moves with the main weight device to the first top dead point.
US11154740B2 Exercise device for squat movement
An exercise device for performing squat movement including a base part for supporting the device against a surface, a first tube member attached to the base part, a second tube member movable with respect to the first tube member, an elastic member resisting the downward movement of the second tube member and moving upward the second tube member with respect to the first tube member, and a seat member for pressing down the second tube member, the seat member being attached to the second tube member.
US11154739B2 Plyometric exercise ladder
A plyometric exercise ladder. A frame has two, spaced-apart, upright posts. A fixed arm is mounted to each upright post, each fixed arm being adjustable along the length of the frame. A removable pull-up bar is supported by the fixed arms. Two spring-loaded arms disposed above the fixed arms are pivotally mounted to the upright posts of the frame. An electromagnet is connected to each spring-loaded arm for initiating movement. A freestanding bracket having at least one scissor arm is connected to the frame and to a wall or other solid structure to support the ladder. In place of the spring-loaded arms and electromagnet, a set of pegs can be removably placed along the length of the upright posts for retaining the pull-up bar as an athlete progresses upwardly. The ladder frame itself can be replaced with a skeletal frame when the ladder is used in conjunction with a conventional squat rack.
US11154737B2 Flame retardant porous plastic resins
Described are flame retardant, porous plastic flame arrestors. The flame retardant, porous plastic flame arrestor is formed by irradiating a flame retardant polymer resin to achieve a fractional melt index, grinding the flame retardant polymer resin into a powder, and sintering the flame retardant polymer resin to form a porous structure. Irradiating the flame retardant polymer resin increases the resin's molecular weight and reduces the resin's melt index through crosslinking.
US11154736B2 Fire or smoke barrier
A fire or smoke barrier (1) having a head box (2) for housing a curtain (4) which is open at its underside to allow the curtain to be deployed and withdrawn. The head box (2) houses a roller (3) for the curtain (4) to be rolled from for deployment and rolled back onto for withdrawal and attached at the bottom of the curtain (4) is a bottom bar (7) for weighing down the curtain (4) when deployed. The head box (2) has one or more apertures (14, 15) for cleaning air circulation and being provided at the, or each, aperture (14,15) with a spring (22) loaded trap (16,17) normally held open by a fusible link (31), the link fusing (31) in event of fire.
US11154733B2 Respiratory protection hood
A respiratory protection hood having a sealed flexible shell including a pressurized oxygen vessel provided with a calibrated output opening leading into the inside space of the flexible shell and a device for trapping at least one portion of the carbon dioxide exhaled by the user that includes a cartridge for adsorbing carbon dioxide having a perforated tube arranged around a volume of carbon dioxide absorbing material. At least one portion of the perforated tube being arranged around the volume of absorbent material in direct communication with the inside space of the hood.
US11154723B2 Laser patch and laser patch procedure set including same
Provided is a laser patch including a patch body having a through hole for laser transmission, a circuit substrate disposed in the patch body, a built-in battery facing the circuit substrate and disposed in the patch body, a laser diode element electrically connected to the circuit substrate and emitting a low-output laser beam to the outside of the patch body by using its own power coming from the built-in battery, and a charging terminal provided in the patch body for selectively supplying electricity to the built-in battery from an external charger.
US11154715B2 Methods for electrical stimulation of the mesencephalic locomotor region for the treatment of gait impairment after stroke using a neurostimulation device
Methods for treating, reducing or reversing a motor deficit in a subject after a stroke comprising administering continuous electrical stimulation to the mesencephalic locomotor region (MLR) of the subject under sufficient conditions so as to treat, reduce or reverse the motor deficit of the subject are provided.
US11154706B1 Pill pacemaker with Bi-V pacing, DDD pacing and AAI with DDD backup pacing
Pill-sized pacemaker system including a pill-size pacemaker and a lead connector, the pacemaker having a distal end including a first screw hook and a proximal end including a first magnetic coupler, the lead connector having a distal end including a second screw hook and a proximal end including a second magnetic coupler, the first and second magnetic couplers being disc-shaped, each including at least one depth-wise electrode, wherein the first screw hook is for screwing the pacemaker to inner heart tissue and for sensing at least one signal from the inner heart tissue, the second screw hook is for screwing the lead connector to inner heart tissue and for sensing at least one signal from the inner heart tissue, and the pacemaker and the lead connector are electrically coupled via each depth-wise electrode of the first and second magnetic couplers when the first and second magnetic couplers are magnetically coupled.
US11154700B2 Ventricular assist device and method
A ventricular assist device includes a stent for placement within a cardiac artery and arranged for placement, the stent arranged to have an open configuration defining a flow path, a rotor sized to fit within the stent and arranged for percutaneous placement the flow path, the rotor including a surface disposed about a central portion and angled with respect to the flow path and having a first plurality of magnets. A collar is sized for placement about the cardiac artery and includes a stator. A power source is coupled to the stator, and the stator and the rotor are arranged to rotate the rotor about an axis. A timing control module controls a rotational speed of the rotor. Accordingly, the surface of the rotor is arranged to move blood along the flow path in response to rotation of the rotor.
US11154699B2 Enteral feeding connector
Embodiments of the application are directed toward an enteral feeding connector, comprising a stem member of a male enteral feeding connector configured to fit inside a shroud skirt of a female enteral feeding connector, wherein an end of the stem member comprises a positive taper funnel-shaped opening. In some cases, an outer radial surface of the end of the stem member is shaped to match a profile of an inner radial surface of the shroud skirt, such that the outer radial surface of the end of the stem member is flush with the inner radial surface of the shroud skirt when the stem member is disposed within the shroud skirt.
US11154695B2 Apparatus for minimally-invasive prevention and treatment of hydrocephalus and method for use of same
An apparatus (10) for minimally-invasive, including non-invasive, prevention and/or treatment of hydrocephalus and method for use of the same are disclosed. In one embodiment of the apparatus (10), a housing (50) is sized for superjacent contact with a skull having a fontanel. Within the housing (50), a compartment (12) includes a pressure applicator (88), such as a fluid-filled bladder (22), under the control of a pressure regulator (14). The pressure applicator (88) is configured to selectively apply an external pressure to the fontanel. The compartment (12) includes a pressure sensor (90) configured to measure intracranial pulse pressure of the fontanel. Further, in one embodiment, the apparatus (10) can cause pulse pressure modulation by adjusting the intracranial pulse pressure via the pressure applicator (88). This enables a non-invasive measurement of the pulse pressure and modulation thereof in infants, for example.
US11154693B2 Balloon catheter having a retractable sheath
An intravascular balloon catheter device is disclosed having an inner member, an outer member disposed about the inner member and further comprising a balloon. A sheath is disposed about the outer member that moves relative to the balloon so as to selectively expose a first portion of the balloon for inflation. A clamp may be used to selectively secure the sheath at a desired position relative to the balloon wherein the desired position is less than full retraction such that a second portion of the balloon remains within the sheath.
US11154690B2 Devices and methods for endovascular access and therapy
The present invention provides for devices and methods for providing endovascular therapy, including facilitating establishment of vascular access, placement of endovascular sheaths, catheter tip localization, and administration of vascular occlusion. The invention includes a vessel cannulation device, an expandable sheath, an occlusion catheter, and a localizer each of which may be provided separately or used as part of a system. One embodiment of the invention is a vessel cannulation device including: a housing having a distal end with a distal tip and a proximal end; a guidewire lumen passing through the housing and at least the distal tip; a sensor coupled to the guidewire lumen; and an advancing member, which is configured for advancing at least one of a guidewire or a sheath and which is operably coupled to the sensor.
US11154689B2 Vascular interventional instrument control device with double guide wires or balloons
A vascular interventional instrument control device capable of operating double guide wires or balloons, includes a main finger assembly, a first sub-finger assembly, a second sub-finger assembly, a driving assembly and a clamping assembly, wherein the main finger assembly, the sub-finger assembly, the driving assembly and the clamping assembly are separately installed to the body structural member and separately connected to the controller through a communication link, one of the operated double guide wires or balloons is clamped by the main finger assembly and the first sub-finger assembly, and the other is clamped by the main finger assembly and the second sub-finger assembly; and the operated double guide wires or double balloons can be separately moved axially or rotated about its own axial direction.
US11154687B2 Catheter patency systems and methods
A patency system for maintaining a patency of an indwelling medical device including an elongated shaft configured to be at least partially received within a portion of the indwelling medical device, and at least one cleaner configured to at least partially dislodge debris formed within the indwelling medical device.
US11154683B2 Humidifier and airway pressure support system including same
A humidifier is for an airway pressure support system for delivering a humidified flow of breathing gas to an airway of a patient. The humidifier includes a water chamber, a conduit, a nozzle, a heater plate, and a number of heating elements. The nozzle is fluidly connected to the water chamber and has an outlet configured to produce a water droplet from water received from the water chamber. The heater plate is coupled to a wall portion of the conduit and is exposed to an interior pathway of the conduit. The heater plate has a first side facing the nozzle and an opposite second side facing away from the nozzle. The first side is positioned to receive the water droplet from the nozzle. The number of heating elements are coupled to the second side of the heater plate.
US11154680B2 Headgear for a respiratory mask
A headgear for a respiratory mask has first and second straps configured to be connected to each other by first and second buckles. The straps are configured to overlap in a region that contacts the rear of a user's head. The overlapping regions of the first and second straps can be positioned in a bifurcated configuration to improve stability on a user's head. The first and second buckles can feature a glider end through which one of the first and second straps can slide and a strap attachment end to which the other strap is permanently connected. In some embodiments, the first and second buckles have two components that are pivotally connected to allow adjustment of the headgear size whilst in a bifurcated configuration.
US11154677B2 Method and apparatus for cleaning a tube
An umbrella-like scraper for cleaning tubes and pipes may include a scraper, an actuator and a hinge configured for selective deployment of the scraper by manipulation of the actuator.
US11154675B2 Anesthesia ventilator for automatic ventilation as well as for the detection of an operating state concerning the automatic ventilation
An anesthesia ventilator, for the automated ventilation of a patient, includes an expiratory port and an inspiratory port for connecting a patient ventilation tube for a breathing gas, a breathing gas delivery unit, a breathing gas volume flow sensor, a breathing gas sensor for detecting a carbon dioxide concentration, a pressure sensor for detecting a pressure of the breathing gas, and a computer. The computer is configured to actuate the breathing gas delivery unit in a first mode of operation as a function of a preset ventilation rate, of the detected pressure and of a preset desired pressure value. The computer is configured to detect the presence of a desired operating state concerning the automated ventilation on the basis of the detected volume flow and of the detected carbon dioxide concentration and to make possible a transition to a second mode of operation in case of detection.
US11154671B2 Nasal devices
A nasal device comprises a first component and a second component and a connector for coupling the first component to the second component and configured to span a nasal septum of the user. The first component comprises a body for insertion into a nasal cavity of a nose of a user. The body comprises a loop structure having an inner surface defining an aperture and a reverse outer surface, the loop structure being configured for alignment with an interior contour of a nasal passage of the nose, a platform spanning the aperture defined by the inner surface of the loop structure, and a valve mechanism disposed on the platform for controlling fluid flow through the aperture. The first component further comprises at least one mount extending from the body.
US11154668B2 Containers for aerosol-generating devices
A container for an aerosol-generating device is provided, including a first compartment including a nicotine source, a second compartment including a delivery enhancing compound, and a transfer section disposed between the first compartment and the second compartment, the first and second compartments being formed from a laminate material including at least one layer of cardboard material and at least one layer of polymeric material, the layer of polymeric material forming an internal surface of the compartments. There is also provided a container where at least one of the first compartment and the second compartment comprises a recessed end, wherein the transfer section is formed by a recess when one end of the first compartment abuts one end of the second compartment. An aerosol-generating system is also provided, including an aerosol-generating device configured to receive the container.
US11154665B2 Hemostatic powder delivery devices and methods
The present invention is directed to a device for expression of a hemostatic powder having an elongated reservoir with a manual air pump, such as a bellows, at a proximal end and an expression port at a distal end. A porous filter is slidably disposed within the reservoir between the bellows, a plunger and the expression port, and a spring is disposed within the reservoir between the air pump and the plunger. The powder is disposed within the reservoir between the porous filter and the expression port, and the pump is in a fluid communication with the expression port through the porous filter and through the powder.
US11154664B2 Interface of needle of medical syringe
An interface of the needle of a medical syringe and realizes that a conical fitting and a conical inclined surface of a syringe barrel and a conical lip and a conical hole of the needle form an interface of the needle; when the conical hole of the needle is plugged onto the conical fitting of the syringe barrel, the needle is fixed onto the conical fitting of the syringe barrel to achieve the purpose of preventing a needle tip from swinging when the needle pierces a muscle or a blood vessel of a human body, so as to avoid misoperation; and after the medical syringe is used, the conical lip of the needle distal away from the needle tip only needs to be pinched flat, the needle can then be separated from the conical fitting of the syringe barrel of the medical syringe.
US11154663B2 Pre-filled safety needle and syringe system
A needle and pre-filled syringe system that provides ultra-low dosage waste and automatic needlestick protection. A syringe assembly is pre-filled with an injection material. A needle head assembly attaches to the syringe assembly. A spacer is disposed between the needle head assembly and the syringe assembly. The spacer has a central opening. The needle head assembly supports a needle with a needle base. When assembled, the needle base passed into the central opening of the spacer. The needle head assembly also contains a safety slide that can selectively cover the needle. During an injection, pressure and/or contact with the plunger head causes the spacer to contact and move the safety slide. The safety slide moves to cover the needle during the injection procedure, therein rendering the needle safe before the injection process is even complete.
US11154660B2 Diabetes therapy management systems, methods, and devices
Diabetes management systems include an insulin delivery device and a monitoring device for detecting at least one characteristic relating to the insulin delivery device. Monitoring devices may comprise pen caps.
US11154653B2 Syringe barrel and syringe-confirmation assembly
A syringe barrel includes a barrel body having a passage extending along a longitudinal axis between a tip opening and a load opening. The passage is configured to permit a plunger to advance therethrough along the longitudinal axis for driving a liquid through the tip opening. The barrel body includes a base portion that is configured to operably engage an injection system. The base portion has a body surface that is shaped to form a light-propagating space alongside the body surface. The light-propagating space extends to reflective ramps of the body surface. The reflective ramps have predetermined sizes and positions to reflect light signals radially away from the barrel body.
US11154652B2 Fluid management system
The invention provides a fluid management system (1) for providing fluid from a fluid source (20) to the body of a patient. The fluid management system (1) includes a compressible chamber (10). A fluid conduit (30) is in fluid communication with the fluid source (20) and with an interior of the compressible chamber (10). A bypass conduit (40) has an inlet end (43) in fluid communication with the fluid source (20) and an outlet end (44) for providing fluid to a trocar (70). The bypass conduit 40 passes either through or around the compressible chamber (10). A first one way valve (80) can admit fluid from the fluid conduit (30) into the interior of the compressible chamber (10). A second one way valve (90) can admit fluid within the interior of the compressible chamber (10) into the bypass conduit (40). A portion (46) of the bypass conduit (40) upstream of the second one way valve (90) is collapsible under the force of selectively applied external pressure when the compressible chamber (10) is at least partially filled with fluid from the fluid source (20), so as to selectively close off the bypass conduit (40) upstream of the second one way valve (90).
US11154650B2 Condensate absorbing and dissipating system
A dressing for treating a tissue site may include a base layer, a sealing member, a first and a second wicking layer, and an absorbent layer. The base layer may have a plurality of apertures and may be adapted to cover the tissue site. The sealing member and the base layer may define an enclosure. The first and the second wicking layer may each be disposed in the enclosure with the absorbent layer positioned between the first and the second wicking layer. A conduit comprised of an absorbent material that is vapor permeable and liquid impermeable may be in fluid communication with the dressing for providing reduced pressure to the dressing. Other dressings, systems, and methods are disclosed.
US11154649B2 Fluidic connector for negative pressure wound therapy
Disclosed herein are several embodiments of a wound treatment apparatus employing a fluidic connector for negative pressure wound therapy and methods of using the same. Some embodiments are directed to improved fluidic connectors for connecting to a wound site, for example a fluidic connector including a reinforcement, and methods of using the same.
US11154646B2 Hemodialysis systems and methods
Hemodialysis systems are described. A hemodialysis system may include a dialysate flow path through which dialysate is passed from a dialysate reservoir, which includes a valved vent to atmosphere, to an ultrafilter. The dialysate flow path includes a pneumatically actuated diaphragm-based dialysate pump for pumping fluid from the dialysate reservoir to the ultrafilter. The hemodialysis system may include a controller for controlling pneumatic actuation pressure delivered to the dialysate pump and at least one valve connecting the dialysate reservoir vent to the atmosphere. The hemodialysis system may be configured to actuate the dialysate pump and the at least one valve to introduce air into the dialysate flow path and expel liquid from the dialysate flow path to a drain.
US11154643B2 Platelet-activated bioadhesive stent coating as an anti-migration mechanism
A stent having an inner surface and an outer surface, the stent comprising a coating composition comprising a platelet-activated adhesive on at least a portion of the outer surface thereof.
US11154641B2 Translucent, dehydrated placental tissue and methods of producing and using the same
Compositions comprising translucent, dehydrated placental tissue and methods of preparing and using those tissues are provided. Repeated dehydration techniques may produce translucent, dehydrated placental tissues, including translucent, dehydrated placental membrane and umbilical cord, with improved visualization and/or handling characteristics. The present invention also includes methods of healing a wound of the skin, eye, nerve, tendon, muscle, dental region, or dura, including burns, comprising applying the translucent, dehydrated placental tissues of the invention to the wound.
US11154637B2 Biodegradable sealant and use of a biodegradable sealant in manufacture of an agent for biological tissue adhesion or repair
A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.
US11154635B2 Porous polyester material
A polymeric material that includes a thermoplastic composition containing a continuous phase that includes a polyester and a copolyetherester elastomer is provided. The copolyetherester elastomer is dispersed within the continuous phase in the form of discrete domains. A porous network is defined within the thermoplastic composition that includes a plurality of nanopores.
US11154630B2 Disinfection device having disinfection light source
A disinfection device includes: a container having a wall that defines a chamber for containing liquid therein; and a light source for transmitting disinfection light to the liquid. The light source is in a spatial relationship with the container so that a distance between the light source and the first light receiving surface of the liquid remains unchanged regardless of a volume of the liquid.
US11154620B2 Compositions, combinations and related methods for photoimmunotherapy
Provided herein are conjugates, compositions and methods for use in photoimmunotherapy, such as photoimmunotherapy induced by activation of a phthalocyanine dye conjugated to a targeting molecule that binds a protein on cell, for example, an IR700-antibody conjugate. In some embodiments, the phthalocyanine-dye conjugate can be activated by irradiation with near-infrared light. Features of the conjugates, compositions and methods, including the dose of the conjugate, provide various advantages, such as lower toxicity and/or improved efficacy. In some embodiments, also provided is a dual label phthalocyanine-dye conjugate in which the targeting molecule is conjugated to an additional fluorescent dye, which can be used for photoimmunotherapy while, for example, also exhibiting improved performance for imaging or detection. Also provided are therapeutic methods using the conjugates and compositions for treatment of diseases and conditions, including tumors or cancers.
US11154619B2 Liposomal compositions with light illumination-induced drug release
Provided herein is a small molecule delivery system with illumination-induced small molecule release based on the binary combination of charged liposomes containing small molecules and oppositely charged conjugates of a peptide with a photosensitizer attached to one end of peptide chain, providing binding to liposomes and their permeabilization upon light illumination.
US11154607B2 Genetically attenuated nucleic acid vaccine
The disclosed compositions and methods provide an approach for the rational development of a nucleic acid vaccine. Methods are disclosed to deliver a viral genome, and/or a representative or derivative of such, that is attenuated but can, when co-delivered with unreplicable compensatory translational tools to a host cell, initially generate phenotypically wild-type, genetically attenuated viruses which infect subsequent cells and elicit a relevant and robust immune response. However, progeny of this initial generation, lacking the compensatory tools delivered to the initial host cells, are both phenotypically and genetically attenuated, thereby compromised in their ability to induce disease.
US11154604B2 Adjuvant compositions and related methods
The present disclosure provides for an adjuvant composition that is suited for injectable as well as transdermal administration. The adjuvant composition generally comprises a lipophile, a polymer of acrylic or methacrylic acid, saline, cholesterol, a saponin, and sodium hydroxide. A vaccine composition is also provided for that generally includes the vaccine composition of the present disclosure and an antigen. A method for vaccinating animals and humans utilizing the adjuvant composition of the present disclosure is also provided.
US11154602B2 Cancer vaccines targeting mesothelin and uses thereof
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen are disclosed. Methods of treating a subject with a mesothelin-expressing tumor and methods of preventing a mesothelin-expressing tumor are disclosed. Modified consensus mesothelin antigen is disclosed.
US11154599B2 Her2/neu immunogenic composition
The invention provides for an immunogenic composition comprising a. a directed adjuvant comprising at least an anti-CD32 moiety linked to a TLR9 ligand and a first peptidic alpha-helix; and b. an immunogen comprising an extracellular Her2/neu domain that is linked to a second peptidic alpha-helix coiled to the first alpha-helix; The invention further provides a kit for producing such immunogenic composition, a vaccine comprising such immunogenic composition and its medical use, such as for treating Her2/neu positive tumor diseases.
US11154596B2 Methods for thrombolysis
Provided herein are methods for use in safe and effective thrombolysis, e.g., in therapy for a potential stroke or acute myocardial infarction (“AMI”) at a maximum arterial patency rate with minimal associated hemorrhagic side effects.
US11154593B2 CNP prodrugs with large carrier moieties
The present invention relates to a CNP prodrug or a pharmaceutically acceptable salt thereof comprising a CNP moiety -D; and a carrier moiety —Z that is conjugated through a moiety -L2- to a reversible prodrug linker moiety -L1-, which reversible prodrug linker moiety -L1- is covalently and reversibly conjugated to -D; wherein -L2- is a chemical bond or a spacer; and —Z is a polymer having a molecular weight of at least 10 kDa. It further relates to pharmaceutical compositions comprising the CNP prodrug or a pharmaceutically acceptable salt thereof, their use as a medicament and to methods of treatment.
US11154592B2 Method of treating Rett Syndrome (RTT) with ghrelin
A method of treating Rett Syndrome (RTT) comprising administering ghrelin to a subject in need thereof.
US11154591B2 Methods of treating alcohol abuse disorder
The invention provides for methods of treating alcohol abuse disorder.
US11154588B2 Use of chelating agent and peptide antimicrobial compounds
The inventors provide the use of a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism to inhibit the growth of and/or kill a plant pathogenic microorganism on a plant; the use of a chelating agent to increase the activity of an antimicrobial that is effective against a plant pathogenic microorganism; a method of inhibiting the growth of and/or killing a plant pathogenic microorganism comprising administering to a plant in need thereof a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism; and a method of increasing the activity of an antimicrobial that is effective against a plant pathogenic microorganism comprising using said antimicrobial with a chelating agent. Also provided is a composition comprising a chelating agent and an antimicrobial agent that is effective against a plant pathogenic microorganism, use of said composition to inhibit the growth of and/or kill a plant pathogenic microorganism on a plant, and a method of inhibiting the growth of and/or killing a plant pathogenic microorganism comprising administering to a plant in need thereof said composition. Further provided is the use of a composition comprising an antimicrobial polypeptide comprising Blad or an active variant thereof to kill, or inhibit the growth of, a plant pathogenic bacterium on a plant, and a method of killing, or inhibiting the growth of, a plant pathogenic bacterium on a plant, said method comprising administering to said plant a composition comprising an effective amount of an antimicrobial polypeptide comprising Blad or an active variant thereof.
US11154584B2 Method and composition for a protein transduction technology and its applications
A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.
US11154581B2 Method for improvement of stiff neck and shoulders
A composition and method for the prevention and/or improvement of dry eye syndrome, dryness of eye and/or stiff neck and shoulder, which contains bilberry fruit extract and is effective with less intake are provided. As one aspect of the present invention, the composition for the prevention or improvement of dry eye syndrome or dryness of eye contains a freeze-dried bilberry fruit extract. As another aspect of the present invention, the composition for the prevention or improvement of stiff neck and shoulder contains a freeze-dried bilberry fruit extract. As another aspect of the present invention, a composition for the prevention or improvement of dry eye syndrome, dryness of eye, and stiff neck and shoulder, contains a freeze-dried bilberry fruit extract. As another aspect of the present invention, a method using a bilberry fruit extract for the improvement of stiff neck and shoulder is provided.
US11154580B1 Composition for preventing, ameliorating or treating acne symptoms using natural extracts as active ingredients
Proposed is a composition for preventing, ameliorating or treating acne symptoms including a Sesamum indicum seed extract, a Quercus robur bark extract and a Houttuynia cordata extract as active ingredients, and at least one natural substance of a Cirsium japonicum extract and Thuja orientalis as an additional active ingredient. The composition for preventing, ameliorating or treating acne symptoms contains, as active ingredients, natural extracts having the effects of prevention, amelioration or treatment of acne by exhibiting high antibacterial activity against C. acnes, which is a strain causative of acne.
US11154578B2 Compositions and methods of use
The present invention provides a composition comprising honey, a preservative and an aqueous carrier, wherein the honey is present in an amount in the range of from 2 to 50% w/w. Uses of the compositions of the invention for the management, treatment or prevention of a respiratory, ophthalmic, ear or vaginal condition in a subject, and for wound management are also described.
US11154575B2 Cancer immunotherapy using CD19-directed chimeric antigen receptors
Several embodiments provided for relate to methods of using of anti-CD19 CAR expressing immune cells in immunotherapy. Provided for herein in several embodiments are immune cell-based (e.g., natural killer (NK) cell) compositions comprising CD19-directed chimeric antigen receptors. In some, embodiments the anti-CD19 binder portion of the CAR is humanized. In several embodiments, the humanized anti-CD19 CAR expressing cells exhibit enhanced expression of the CAR as well as enhanced cytotoxicity and/or persistence.
US11154574B2 Tumor infiltrating lymphocytes and methods of therapy
Genetically modified compositions, such as non-viral vectors and tumor infiltrating lymphocytes, for the treatment of gastrointestinal cancer are disclosed. Disclosed are methods of utilizing a CRISPR system to generate genetically modified compositions. Also disclosed are the methods of making and using the genetically modified compositions for the treatment of gastrointestinal cancer.
US11154572B2 Methods of treatment with natural killer cells matched for killer immunoglobulin receptor type
The present invention concerns methods of treating a disease such as leukemia in a subject by administering natural killer (NK) cells. In particular aspects, HLA-C1-licensed KIR2DL2/3 and KIR2DS2 NK cells are administered to a subject with an HLA-C genotype either homozygous or heterozygous for the C1 allele, or HLA-C2 licensed cells are administered to a subject with an HLA-C genotype homozygous for the C2 allele. In further aspects, the NK cells are genetically modified to express a chimeric antigen receptor and interleukin 15.
US11154570B2 Iron-polysaccharide complexes and methods for the preparation thereof
The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
US11154567B2 Method for treating liver disease with kinsenoside
A method for treatment of a liver disease, the method including administering kinsenoside to a patient in need thereof.
US11154564B2 Composition for cough
The present invention relates to a new composition for use in the treatment of cough comprising one or more polysaccharide fractions of plantain, one or more polysaccharide fractions of marshmallow, honey, brown sugar, one or more polyphenolic fractions of agrimony comprising tannins.
US11154563B2 Immunoproteasome inhibitors
Provided herein are compounds, such as a compound of Formula (I), as described herein, or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
US11154562B2 Methods of reducing risk of preterm birth
This disclosure generally relates to methods for reducing the risk of preterm birth in a pregnant human female patient that include subcutaneous administration of HPC. The disclosure relates in part to the discovery that subcutaneous administration of HPC is actually feasible and can result in sufficient plasma levels of HPC in pregnant patients that can reduce the risk of preterm birth.
US11154560B2 Methods for treating ocular inflammatory diseases
A method of treating blepharitis includes administering to the affected eye of a subject an effective amount of an active ingredient in an ophthalmically acceptable vehicle for a sufficient period of time to treat blepharitis. The active ingredient consists essentially of a glucocorticoid in an ophthalmically acceptable vehicle that includes an aqueous polymer suspension that when mixed with tear fluid provides a sustained release of said active ingredient. The aqueous polymer suspension includes a carboxyl-containing polymer having less than about 5% by weight cross-linking agent and has a viscosity in a range from about 1,000 to about 30,000 centipoises. A kit includes: (a) a composition comprising about 0.1% by weight dexamethasone in this ophthalmically acceptable vehicle and (b) instructions for using the composition of (a) for the treatment of blepharitis.
US11154559B2 Methods and compositions of bile acids
Methods and compositions are provided for treating metabolic disorders by modulating bile acid levels. Generally, the methods and compositions can modulate bile acid levels, such as serum bile acid levels, to treat a metabolic disorder. In one embodiment, a method of modulating a bile acid level includes measuring a bile acid level and delivering a composition effective to modulate the bile acid level. A method for modulating a bile acid profile includes comparing a bile acid profile to a target profile and delivering a bile acid cocktail to increase bile acid levels. In another embodiment, a pharmaceutical composition for increasing bile acid levels includes a bile acid cocktail effective to increase bile acid levels. The composition is further useful as part of an implantable system.
US11154557B2 Antiviral prodrugs and nanoformulations thereof
The present invention provides prodrugs and methods of use thereof.
US11154555B2 Treatment of cancer
Provided herein are compositions and methods for the treatment of a hematological malignancy. Also disclosed herein are compositions and methods for the treatment of Ewings Sarcoma. Said compositions comprise isoform selective pyrrolo-pyrazole PKC inhibitors.
US11154554B2 Therapeutic combinations of a MEK inhibitor and a BTK inhibitor
Therapeutic combinations of a MEK inhibitor and a Bruton's tyrosine kinase (BTK) inhibitor are described. In some embodiments, the invention provides pharmaceutical compositions comprising combinations of a MEK inhibitor and a BTK inhibitor and methods of using the pharmaceutical compositions for treating a disease, in particular a cancer.
US11154551B2 HDAC1,2 inhibitors and methods of using the same
Disclosed herein are methods for treating a cancer and a method for sensitizing a cancer to a chemotherapeutic agent. Each method administers an agent that selectively inhibits HDAC1 and HDAC2 to a subject in need thereof. Also disclosed herein are methods for determining if a cancer is sensitive to an agent that selectively inhibits HDAC1 and HDAC2 and methods for monitoring the efficacy of a treatment for a cancer that includes administration of an agent that selectively inhibits HDAC1 and HDAC2.
US11154550B2 Treatment for neurodegeneration
Provided is a method of treating and/or preventing Wolfram Syndrome (WS)-related neurodegeneration (i.e. of Wolfram Syndrome-Associated Neuronal Degeneration), by increasing the expression and/or functional activity of p21. A method of screening for pharmacological agents useful in treating and/or preventing such conditions is also provided.
US11154548B2 Monosubstituted or polysubstituted amphiphilic hypocrellin derivative, and preparation method and application thereof
The invention discloses a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, and a preparation method and application thereof. The amphiphilic hypocrellin derivative substituted by a group containing PEG, a quaternary ammonium salt or the like prepared according to the invention has an obvious red shift in its absorption spectrum and a significantly enhanced molar extinction coefficient, compared with the parent hypocrellin, can efficiently produce singlet state oxygen and other reactive oxygen species under photosensitive conditions; has different amphiphilicities and increased biocompatibility with cells or tissues by regulating its hydrophilicity and hydrophobicity; can meet the requirements of different clinical drugs, and solves the requirements of different drug delivery methods for different drug hydrophilicity and lipophilicity. Under identical conditions, the amphiphilic hypocrellin derivative photosensitizer according to the invention has higher ability to photodynamically inactivate tumor cells than the first and second generation commercial photosensitizers.
US11154547B2 Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
Methods of use, formulations, and devices for delivering therapeutic drugs locally to the region of the spleen are described herein. A method for treating sepsis and other inflammatory disease conditions can include inserting a drug delivery system inside the body, advancing the device to the spleen through the splenic artery, splenic vein or other blood vessel adjacent to the splenic nerves, or within a ligament associated with the spleen, such as the splenorenal or gastrosplenic ligaments.
US11154543B2 P38 MAP kinase inhibitors for wound healing
Methods of the invention treat, reduce, or reverse fibrosis of a bodily tissue by administering to the local affected tissue a composition comprising an inhibitor of p38 MAP kinase, which treatment leads to a reduction or reversal of fibrosis.
US11154539B2 Pharmaceutical compounds
The invention provides a compound for use in the treatment of T-Cell Acute Lymphoblastic Leukaemia (T-ALL), the compound having the formula (1): or being a pharmaceutically acceptable salt thereof; wherein: n is 0, 1 or 2; Ar1 is selected from an optionally substituted phenyl, pyridyl, thienyl and furanyl; Q1 is selected from C(═O), S(═O) and SO2; A is absent or is NR2; R1 is selected from: hydrogen; an optionally substituted C1-6 non-aromatic hydrocarbon group; and optionally substituted 3- to 7-membered non-aromatic carbocyclic and heterocyclic rings containing one or two heteroatom ring members selected from O, N and S, and bridged bicyclic heterocyclic rings of seven to nine ring members of which one or two are nitrogen atoms, the carbocyclic and heterocyclic rings and bridged bicyclic heterocyclic rings; R2 is selected from hydrogen and C1-4 alkyl; or NR1R2 forms an optionally substituted 4- to 7-membered non-aromatic nitrogen-containing heterocyclic ring optionally containing a second heteroatom ring member selected from nitrogen and oxygen.
US11154526B2 Methods of treating mixed dyslipidemia
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
US11154524B2 Therapeutic compositions of decanoic acid and arginine
Compositions including a complex of fatty acids (e.g., including one or more C4 to C40 fatty acids, such as a C4 to C20 fatty acid) and one or more amino acids (and particularly one or more amino acids having electrically charged basic side chains, e.g., Arginine, Lysine, etc.) for use as an anti-pathogenic composition. In particular, described herein are compositions of decanoic acid:Arginine in which the decanoic acid and Arginine for a complex having a lamellar supramolecular structure.
US11154520B2 Combination therapy for metastatic cancer
The present invention relates to methods and sets of drugs for the effective treatment of metastatic cancer and the administration of a set of drugs that overcome mechanisms of resistance to DNA-damaging agents, thereby sensitizing cancer cells to said DNA-damaging agents. The methods involve the administration of a set of drugs comprising melphalan, BCNU, hydroxocobalamin, and ascorbic acid. In a preferred embodiment, ethanol is also added to the set of drugs and bone marrow toxicity is reversed with an infusion of bone marrow stem cells. The methods also involve the depletion of GSH in tumors and the selective delivery of drugs to solid tumors. The methods also involve preventing the loss of catalase function and preventing oxidant-induced hemolysis and/or methemoglobin formation in subjects treated with oxidant drugs or agents that generate hydrogen peroxide, wherein said methods comprise the systemic administration of ethanol.
US11154519B2 Inhibitors and their uses
The present invention relates to inhibitors of PPP1 R15A and PPP1 R15B and their use in therapy, particularly in the treatment of a disease state alleviated by the inhibition of PPP1 R15A and PPP1 R15B, for example a disorder associated with accumulation of misfolded proteins or proteostatsis disorder. Compounds of the invention include compounds having the formula IA or a pharmaceutically acceptable salt thereof, wherein R1a, R3a, R5a, Xa and Ya are as defined herein.
US11154517B2 Use of cannabinoids in the treatment of epilepsy
The present disclosure relates to the use of cannabidiol (CBD) for the treatment of atonic seizures. In particular the CBD appears particularly effective in reducing atonic seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; Aicardi syndrome; CDKL5 and Dup15q in comparison to other seizure types. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).
US11154516B2 Use of cannabinoids in the treatment of epilepsy
The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of “treatment-resistant epilepsy” (TRE). In particular, the disclosure relates to the use of CBD of treating TRE when the TRE is Dravet syndrome; myoclonic absence seizures or febrile infection related epilepsy syndrome (FIRES). The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).
US11154513B2 Semifluorinated compounds
The present invention is directed to certain semifluorinated compounds and to compositions comprising such compounds. The invention further provides the use of the compounds and of the compositions as medicaments for topical administration to the eye.
US11154511B2 Albumin pharmaceutical composition and preparation method therefor
Disclosed herein is an albumin pharmaceutical composition, comprising albumin and at least one amino acid having a relative molecular mass of 145-175. Clinically, the albumin pharmaceutical composition can effectively reduce undesirable responses, such as rash, urticaria, anaphylaxis and possible immune responses in the human body caused by albumin polymers and dimers, thereby further ensuring the safety in clinical medication.
US11154507B2 Freeze-dried aripiprazole formulation
An object of the present invention is to provide a freeze-dried aripiprazole powder formulation that exhibits good dispersibility and is easily dispersed into a homogenous suspension when reconstituted with water. The present invention provides a freeze-dried aripiprazole formulation obtained by a process comprising the steps of spraying for freezing an aripiprazole suspension containing (I) aripiprazole, (II) a vehicle for the aripiprazole, and (III) water for injection, and drying.
US11154497B2 Method for manufacturing medicated chewing gum without cooling
An improved method for manufacture of chewing gums containing active ingredient(s) that preserves the efficacy of the active ingredient(s) by avoiding exposure to high heat and extreme cold during milling that can otherwise degrade the active's efficacy. A chewing gum base is used, along with one or more therapeutically-active ingredients, one or more sweeteners (alcohol-based and/or natural), and one or more flavorings and optional flavor modifiers. The method generally comprises heating the gum base in ovens to melt the gum base. Separately, the active ingredient(s), sweeteners and flavorings are combined in a mixer. The melted gum base is added to the mixer and cools to produce a particulate mixture. As mixing continues the mass cools to room temperature and forms granular pieces. The granular pieces are ground into a powder at room temperature, mixed at room temperature with tableting excipients, and tableted. Several variations on the foregoing are also described.
US11154488B2 Cosmetic compositions containing oxazoline functionalized polymers and amino silicone compounds
Disclosed are compositions, systems and methods for treating keratinous fibers such as hair. The compositions and systems comprise an oxazoline functionalized polymer and an amino silicone compound. The compositions and methods are employed to improve the quality of the keratinous fibers.
US11154487B2 Oral care compositions and methods for the same
A film forming composition and methods for preventing acid erosion of teeth and preventing the formation of caries on teeth are disclosed. The film forming composition may include a hydrophobic copolymer, a fluoride compound, and an orally acceptable solvent. The film forming composition may also include a cellulose derivative, a rosin, a fluoride compound, and an orally acceptable solvent.
US11154485B2 Chitosan-containing antiperspirant cosmetic agents which are free of halides and/or hydroxy halides of aluminum and/or zirconium
The invention relates to an antiperspirant cosmetic agent which includes at least one specific chitosan and which is free of aluminum-containing compounds, in particular free of halides and/or hydroxy halides of aluminum and/or zirconium. The present invention further relates to the use of a specific chitosan and to a non-therapeutic method for reducing body perspiration. Adding or using the at least one specific chitosan ensures that the sweat gland(s) is/are effectively influenced, thus resulting in a significant reduction in underarm perspiration even in the absence of antiperspirant aluminum-containing compounds.
US11154482B2 Peptide, composition and method for anti-hair graying
An isolated peptide consisting of FKCRRWQWRMKKL (SEQ ID NO: 1) for preserving the natural color of the hair, or slowing the decay in the natural pigment production of the hair follicle, or reducing the appearance of hair graying is provided. Also disclosed herein are methods and compositions for preserving the natural color of the hair, or slowing the decay in the natural pigment production of the hair follicle, or reducing the appearance of hair graying in a mammal subject.
US11154474B2 Chemical formulations and their use in neutralizing or eliminating odors
The present invention is a chemical formulation and method of using the chemical formulation to neutralize or eliminate odors on a surface. In one aspect, the chemical formulation is an aqueous solution of multi-valent citrate salts and a surfactant that may further comprise a fragrance and/or a color and/or a chelating agent. The method comprises the steps of applying this formulation in sufficient volume to saturate the surface thereby neutralizing or eliminating the odor. In another aspect, the formulation of multi-valent citrate salts may be applied in solid form to an odorous aqueous solution or may be used to coat an absorbent matrix that is expected to receive an odorous aqueous solution.
US11154472B2 Compositions comprising solvent, a monoalcohol, glycerin, and thickener
Compositions are provided for removing nail polish that include a co-mixture of monoalcohol, glycerin, and solvent consisting of C2-C3 monoalcohol, glycerin, and a solvent selected from acetone, a C2-C4 alkyl acetate, and combinations thereof. The composition for includes a co-mixture of monoalcohol, glycerin, and solvent that consists of C2-C3 monoalcohol; glycerin; and less than 55% by weight of solvent selected from acetone, a C2-C4 alkyl acetate, and combinations thereof. The glycerin and the C2-C3 monoalcohol are present in a glycerin to C2-C3 monoalcohol weight ratio of greater than about 0.6. If the solvent includes C2-C4 alkyl acetate then the concentration of C2-C4 alkyl acetate is less than 30% by weight. The composition further includes polyacrylamide and water. The concentration by weight of water in the composition is less than the concentration by weight of glycerin. Methods are also provided.
US11154470B1 Anti-inflammatory and senolytic dental care product with tooth whitening characteristics
The present invention relates to the field of dental care, e.g., with toothpaste, tooth gel, mouth-wash, mouth spray or oral care foam. In particular, it provides an anti-inflammatory and senolytic dental care product with tooth whitening characteristics. The dental care product comprises calcium phosphate particles of a specific size, the self-assembling peptide P11-4 or oligopeptide 104 of SEQ ID NO: 1, an extract of a plant of the genus Rhododendron, preferably, an alpine rose or Alpenrose such as Rhododendron ferrugineum or Rhododendron hirsutum, and an extract of a plant of the genus Leontopodium, such as Leontopodium nivale, which is also called Edelweiss. The dental care product may further comprise an extract of a plant of the genus Eleutherococcus, such as Eleutherococcus senticosus, which is also designated Siberian ginseng or Acanthopanax senticosus. In addition to the proven tooth whitening characteristics of said product, which can be a medicinal product or a pharmaceutical composition, it further has a senolytic and anti-inflammatory effect. Thus, the invention provides a method for tooth whitening as well as a method of treating periodontal disease, and/or for eliminating or reducing the number of senescent cells in the gums of a subject. The gums of a subject can thus be rejuvenated, potential loose teeth stabilized, and the well-being increased.
US11154468B2 Oral care compositions and methods of use
This invention relates to oral care compositions comprising a zinc source comprising zinc oxide and zinc citrate; a stannous source comprising stannous pyrophosphate; a fluoride ion source comprising sodium fluoride; and an organic buffer, as well as to methods of using and of making these compositions.
US11154467B2 Concentrated shampoo dosage of foam designating hair conditioning benefits
Described herein is a dosage of foam including from about 5 cm3 to about 70 cm3 of the foam. The foam includes from about 0.5 g to about 4 g of a detersive surfactant; from about 0.001 g to about 4 g propellant, a foam density of from about 0.05 g/cm3 to about 0.35 g/cm3; a bubble size distribution including an R32 of from about 5 μm to about 100 μm; and a gloss unit measurement of from about 4 to about 40 GU. The propellant is selected from 1,3,3,3-tetrafluoroprop-1-ene, 1,1 difluoroethane, and mixtures thereof.
US11154464B2 Aerosol device for hair shaping and/or hairstyle hold
The present invention relates to an aerosol device comprising: —a container containing a cosmetic composition which comprises one or more powders in a content of less than 7% by weight relative to the total weight of the composition, and—a dispensing head comprising a body and an end part comprising at least two outlet orifices configured to allow spraying of the composition about a longitudinal axis of the end part in at least two different directions, the dispensing head comprising at least first and second chambers, through which the composition stream successively passes before it exits via the outlet orifices.
US11154460B2 Personal prescription dispenser
Disclosed is a method and apparatus for transporting and dispensing medications for a patient according to a medication schedule for the patient. A smart container from a pharmacy is received at the patient's site and the container is checked to make sure that the container was delivered to the correct patient site. The smart container contains a memory device that contains identification information of the patient, dosage and treatment instructions for the patient. This information and the medication were checked for compatibility before the smart container was delivered. The identity of the patient at the patient's site is then checked and the patient performs on or more biometric tests before the medication is dispensed by the smart container. Upon taking the medication and providing video proof thereof, the smart container is returned to the pharmacy.
US11154455B2 Portable massage device
An improved portable massage device includes a first housing including a plurality of acupressure protrusions formed on an upper surface thereof and spaced apart from each other. The portable massage device further includes a battery supplying power, a motor connected to the battery to be turned on/off, and a rotating member mounted to surround the motor. In addition, the portable massage device includes a shield plate provided on the rotating member, at least one magnet detachably attached to the shield plate so that the shield plate vibrates when the motor rotates, a case accommodating the motor, a first switch connected to and controlling the battery to be turned on/off, and a second housing detachably combined with the first housing. The battery and the case are accommodated in the first housing or the second housing.
US11154454B2 CPR chest compression device with releasable base member
A CPR device having a base member configured to be placed underneath a patient, a chest compression mechanism configured to deliver CPR chest compressions to a patient, a support leg configured to support the chest compression mechanism at a distance from the base member, a clamp mechanism coupled to the support leg, and a release mechanism coupled to the support leg and the clamp mechanism. The clamp mechanism may be configured to attach the support leg to a lock component of the base member in a latch-closed configuration and to release the support leg from the lock component in a latch-open configuration. The clamp mechanism may further be configured to transition from the latch-closed configuration to the latch-open configuration when the lock component of the base member impinges upon an external portion of the clamp mechanism.
US11154451B2 Compression device for the foot
A compression device for the foot including a wrap adapted to surround the foot, the wrap including at least two bladders which when inflated conform to the shape of the foot to provide compression, the bladders being positioned on the wrap so that a first bladder focuses compression on the heel of the foot and a second bladder focuses compression on the arch of the foot; a channel attached to each bladder for independently delivering fluid to each bladder; and a controller attached to the channels that generates and independently controls the flow of fluid to the bladders.
US11154450B2 Exoskeleton structure
An exoskeleton structure includes a leg part to be fastened to a leg of a user, a foot part to be fastened to a foot of a user, a mechanical linking assembly linking the leg part to the foot part, and including a first pivot allowing the foot part to rotate relative to the leg part about a first axis when the foot of the user makes an internal/external rotation movement relative to the leg, and a second pivot allowing the foot part to rotate relative to the leg part about a second axis when the foot of the user makes a pronation/supination movement relative to the leg. The first pivot is at a height greater than or equal to 20 centimetres from the ground, and the distance between the first axis of rotation and the second axis of rotation is less than or equal to 5 centimetres.
US11154448B2 Funerary viewing system and method
A funerary method includes disposing a deceased on an insert, the insert constructed primarily of paper material, and having side and end walls. At least one side wall and the end walls all have approximately the same height. The insert is provided on a tray having two end panels and a plurality of wood or metal side panels affixed to a bottom panel. The method also includes employing at least a first fabric segment to cover at least a portion of a top edge of at least one sidewall of the insert and at least a portion of the deceased human body, such that the deceased human body is sufficiently visible for identification. The method also includes later removing the insert and the deceased human body from the tray. A second insert having a second deceased human body is then disposed thereon on the tray.
US11154445B2 Bed systems and methods
A bed is provided. The bed may include a lift system which raises and lowers a support deck of the bed. The lift system may include multiple individually actuatable lift systems. The bed may include a powered bed mover system.
US11154442B1 Federated sensor array for use with a motorized mobile system and method of use
A motorized mobile system includes a human machine interface (HMI) to provide control instructions to the system. A controller in the system receives the control instructions and generates a control signal, wherein the generated control signal causes one or more components of the motorized mobile system to respond. One or more sensors generate health data related to a user, wherein the health data is stored in a secure memory connected to the controller, and wherein the stored user health data is used to bias the control signal for the motorized mobile system.
US11154439B2 Absorbent article with strong and weak bonded portions
An absorbent article includes an absorber having a front surface side sheet, a back surface side sheet disposed on the back surface side of the front surface side sheet, cells each of which is surrounded by bonded portions of the front surface side sheet and the back surface side sheet and inside each of which the front surface side sheet and the back surface side sheet are not bonded, and particulate materials which include superabsorbent polymer particles and which are contained in each of the cells. The bonded portions are arranged in continuous line shapes or dotted line shapes so as to form same-sized regular hexagons, which connect each other as unit shapes to be a honeycomb shape. All the cells are the same-sized regular hexagonal cells each of which is surrounded by the bonded portions.
US11154435B2 Absorbent products having improved packaging efficiency
A package comprising an interior space and an exterior surface may have a plurality of disposable absorbent articles disposed within the interior space of the package. Each of the disposable absorbent articles may have a topsheet; a backsheet; an absorbent core located between the topsheet and the backsheet. The absorbent products may exhibit an In-Bag Stack Height of less about 80 mm as measured according to an In-Bag Stack Height Test.
US11154430B2 Tampon pledget for increased bypass leakage protection
The present invention provides a tampon pledget with one or more of the following properties: increased absorbency rate; high absorbent capacity and fluid retention; rapid expansion potential; and ease of ejection of the pledget from the applicator. Surprisingly, the one or more properties are achieved by using a modified dual cross-pad, folded, compressed tampon pledget design.
US11154429B2 Method for fabricating absorbent articles
The present invention relates to a method for fabricating absorbent article having multiple layers, and deformed zones of targeted performance, and colored regions, the method comprising the steps of forming discrete features on at least one layer, printing colored regions on at least one layer, integrating multiple layers to form an absorbent assembly, and cutting the absorbent assembly into individual absorbent articles, wherein the steps are carried out continuously.
US11154423B2 Systems and methods for cross-linking treatments of an eye
A system for corneal treatment includes a light source that activates cross-linking in at least one selected region of a cornea treated with a cross-linking agent. The light source delivers photoactivating light to the at least one selected region of the cornea according to a set of parameters. The system includes a controller that receives input relating to the cross-linking agent and the set of parameters. The controller includes computer-readable storage media storing: (A) program instructions for determining cross-linking resulting from reactions involving ROS including at least peroxides, superoxides, and hydroxyl radicals, and (B) program instructions for determining cross-linking from reactions not involving oxygen. The controller executes the program instructions to output a calculated amount of cross-linking in the at least one selected region of the cornea. In response to the calculated amount of cross-linking, the light source adjusts at least one value in the set of parameters.
US11154422B2 Surgical cassette manifold, system, and methods thereof
Eliminating leaks of molded fluid channels by providing a front housing, rear housing, and a gasket, wherein the front housing has one or more molded fluid channels and one or more seal channels, and wherein at least a portion of the gasket is located between the front and rear housing; molding the gasket onto the rear housing to create a single unit, wherein the gasket has one or more seal lips configured and dimensioned to couple with the one or more seal channels; and assembling the front housing to the rear housing having the gasket, wherein the one or more seal lips couple with the seal channels. A surgical cassette manifold having a front and rear housing, and a gasket therebetween. The front housing having molded fluid channels that mate with the gasket and the gasket having multiple valves and a sensor/diaphragm accessible through the rear housing.
US11154421B2 System and method for providing pressurized infusion transfer reservoirs
Apparatus, system and method for providing pressurized infusion of liquids and, more particularly, providing a stable and pressurized flow of fluid to the eye during surgery. Aspiration fluid may be received via an aspiration line at a first peristaltic pump, where aspiration fluid is transferred to a Venturi tank reservoir coupled to a second peristaltic pump. Fluid from a fluid source is provided via a third peristaltic pump to a pressurized infusion tank. A determination is made if the pressure in the pressurized infusion tank is at a predetermined level, where fluid may be transferred from the pressurized infusion tank to an irrigation line when pressure in the pressurized infusion tank is determined to be at the predetermined level. Alternate activation of a plurality of aspiration and irrigation lines are also provided.
US11154420B2 Ophthalmic injection device
A device for controlled delivery of an injection material to tissue spaces of an eye that are not normally open, such as the subconjunctival space, the suprachoroidal space and the subretinal space. The device comprises an elongated body with a hollow cannula at the distal end, a slidable plunger at the proximal end, and a reservoir for the material to be injected residing between the cannula and the plunger. The plunger is mechanically coupled to a source of force such as a spring or pressurized gas reservoir such that an injection force is applied to the injection material within the device prior to delivery of the injection material into an eye. A valve that is normally closed to prevent flow of the injection material during application of the injection force is placed in the flow path between the cannula and reservoir. Due to the injection force placed on the injection material, actuation of the valve allows controlled flow from the reservoir through the cannula and into the tissue space.
US11154417B2 Hand-held cryotherapy device including cryogen temperature controller and method thereof
This application relates to a hand-held cooling device for supplying a cryogen to a target region for cryotherapy. The device can include a cryogen transfer unit configured to receive a first cryogen from an external cryogen reservoir, the first cryogen including i) a first amount of a liquid phase cryogen and ii) at least one of a first solid phase cryogen and a first gas phase cryogen. The device can also include a nozzle configured to spray a first modified cryogen to the target region. The device can further include a cryogen liquefier disposed between the cryogen container and the nozzle and configured to cool the first cryogen received from the cryogen transfer unit and output the first modified cryogen to the nozzle, the first modified cryogen including at least a second amount of the liquid phase cryogen more than the first amount of the liquid phase cryogen.
US11154416B2 Menstrual cup
A menstrual device with a reservoir portion attached to a rim portion where the rim of the device is configured to improve use and comfort. The edge of the reservoir portion may be molded into the defined geometry of the rim portions. Additionally, the rim may have one or more channels and/or elements positioned within the defined geometry of the rim.
US11154414B2 Apparatus and methods for treating venous occlusive disorders
Apparatus, methods and systems for treating venous occlusive disease are provided. Generally, devices include a soft extension member that is adapted to be mounted at a proximal end of a therapeutic vacuum device. The soft extension member includes a proximal end composed of a tissue contacting portion configured to receive a tissue to be treated, and a distal end composed of a collar configured to be mounted onto an exterior surface of a vacuum chamber. Apparatus, methods and systems for increasing clitoral and cavernosal tumescence by application of a vacuum are also provided.
US11154412B2 Medical device release system
A medical device system may include an elongate shaft having a lumen extending from a proximal end to a distal end, a release wire disposed within the lumen of the elongate shaft configured to releasably attach a medical device to the distal end of the elongate shaft, and a securement member fixedly attached to the proximal end of the elongate shaft and to a proximal end of the release wire. A proximal portion of the securement member may be configured to translate proximally away from the proximal end of the elongate shaft upon application of a proximally-directed force to the proximal portion of the securement member while the elongate shaft is maintained in a fixed position, wherein the proximal portion remains connected to the proximal end of the elongate shaft after proximal translation away from the proximal end of the elongate shaft.
US11154408B2 Management of wireless transmission rate of control signals for power assistive devices
A system and method for transmission of a signal for a powered assistive device has a sensor node with a wireless transmitter adapted for digitally transmitting a transmitted signal, the sensor node adapted for receiving and monitoring a sensor signal from a sensor attached to a user, and a master node with a controller and a wireless receiver for receiving the transmitted signal from the wireless transmitter. The master node processes the transmitted signal and communicates a control signal to the powered assistive device. The wireless transmitter transmits the transmitted signal at a first rate when the wireless transmitter adapted to transmit the transmitted signal at a first rate when the sensor signal is indicative of the rest state and to transmit the transmitted signal at a second rate when the sensor signal is indicative of the active state, the second rate being greater than the first rate.
US11154404B2 Spinal fixation system
A spinal fixation system includes an expandable disc replacement body and an adjustment mechanism. The expandable disc replacement body includes a first wall, a second wall, a hinge connecting the first wall and the second wall, and a first bone-screw receiving section at a proximal end of the first wall. The adjustment mechanism is positioned between the first wall and the second wall, and an angle between the first wall and the second wall can be varied by movement of the adjustment mechanism.
US11154400B2 Delivery system and methods for reshaping a heart valve annulus, including the use of magnetic tools
Delivery systems, methods and associated devices to facilitate delivery and deployment of a heart implant. Such delivery systems and methods of delivery include use of a pair of magnetic catheters, including an anchor delivery catheter carrying an anchor, which can be stacked with or can be axially offset from the magnetic head. Such systems further include use of a puncturing guidewire advanceable through the magnetic head of the anchor delivery catheter to establish access to a chamber of a heart and which is attached to a bridging element such that continued advancement of the guidewire draws a bridging element attached to the first anchor across the chamber of the heart while the bridging element remains covered by the magnetically coupled catheters. Methods and devices herein also allow for cutting and removal of a bridge element of a deployed heart implant.
US11154396B2 Assembly for replacing the tricuspid atrioventricular valve
An assembly for the tricuspid orifice of a human heart, comprises an external frame connected to an internal stent carrying a tricuspid valve bioprosthesis and a sealing skirt. The external frame is configured to hold its position in the native tricuspid annulus. The internal stent is connected to the external frame by one or more fixing strands. The sealing skirt covers the interstitial space existing between the external frame and the internal stent. Developments are described which comprise in particular the use of a deformable region of the frame, various alternative embodiments of the sealing skirt, the use of a frame composed of multiple sub-sections, the use of fixing strands between the stent and the frame and of fixing elements for fixing the assembly to the native tissue, the use of sensors and/or actuators, and also the use of a stent in the inferior vena cava. Method aspects are described.
US11154392B2 Stent graft with internal tunnels and fenestrations and methods of use
A thoraco-abdominal branch graft prosthesis includes a lumen main graft component that defines a lumen and at least one main graft wall fenestration. An open distal end of the main graft component is tapered and has a smaller diameter than the proximal end of the main graft component. At least one tunnel graft component of the branch graft prosthesis defines at least one tunnel graft fenestration. The tunnel graft component is within the main graft lumen defined by the luminal main graft component. A luminal wall of the tunnel graft component is fixed to the luminal wall of the main graft component. The fenestration of the tunnel graft wall is aligned with the fenestration of the main graft wall. The thoraco-abdominal branch graft prosthesis can be implanted in a patient at a site of a thoraco-abdominal aneurysm.
US11154391B2 Ureteral stent for placement in a kidney and bladder
Provided is a ureteral stent for placement in a bladder, a kidney and a ureteral passageway connecting the bladder and the kidney. The ureteral stent includes a solid bladder portion free of a lumen positionable in the bladder, a tubular kidney portion positionable in the kidney and the ureteral passageway, and a tether connecting the bladder portion and the ureter portion to allow the bladder portion to float in the bladder and to allow a ureter orifice connecting the ureteral passageway to the bladder to move between a compressed state and an uncompressed state. By not having a lumen, the solid bladder portion allows the bladder to have a smaller diameter while maintaining a necessary uncoil force. The smaller diameter also allows the bladder portion to be inserted into a scope alongside a pusher tube, thereby avoiding loading the bladder portion onto a guidewire.
US11154389B2 Assemblies and methods of sterilizing a wet stored implant
Aspects of the disclosure relate to “wet” transcatheter prosthetic heart valve or other implant packaging and assemblies in which a prosthetic heart valve or other implant is loaded into a first portion of a delivery device and positioned within a container in which sterilizing fluid is retained to sterilize inside of the container as well as provide moisture to prevent the implant from drying out. The disclosure also relates to methods of sterilizing the disclosed assemblies. Some disclosed methods include at least two sterilizing steps and adjustment of a shaft seal or formation of multiple seals maintaining sterilizing fluid within the container so that areas underneath the shaft seal(s) can also be sterilized.
US11154388B2 Surgical instruments and methods of use
Surgical instruments suitable for use during surgical procedures. The surgical instruments include first and second halves coupled together at a pivot so that the halves define a handle and functional portions at proximal and distal ends of the instrument, respectively. The functional portion terminates at a blunt distal end and includes scissors, a base section disposed between the scissors and blunt distal end and having a first clamping feature, a tapering section disposed between the first clamping feature and blunt distal end and having gripping features, and opposing tips disposed between the tapering section and distal end of the instrument and having second clamping features.
US11154387B2 Assistance system for dental treatment, in particular by changing a tooth color
An assistance system for dental treatment, particularly for changing tooth color, is provided herein, including a measuring device for determining tooth data. The data captured is transmitted from the measuring device to a data processing means. The data processing means includes a camera for capturing a tooth mage. Using a selection means, a color change level for the tooth image or the teeth is specified and, thereafter, the tooth image is adapted based on the selected color change level using an adaptation means. Thus, it is possible to show the patient an image of a color change of his teeth caused by the dental treatment in relation to the appearance of his face, so the patient can judge a color change in relation to his or her face.
US11154380B2 Dental restoration scalpel
A scalpel that safely and efficiently removes excess dental composite from the surfaces of teeth. A method for removing excess dental composite from a dental surface using this dental scalpel.
US11154373B2 Control of computer-assisted tele-operated systems
An instrument system includes an instrument, a drive system, and a controller operably connected to a first drive mechanism and a second drive mechanism of the drive system. The controller is configured to operate the first drive mechanism and the second drive mechanism drive a flexible tensioning member of the instrument to cause movement of an end effector of the instrument while maintaining a tension applied to the flexible tensioning member of the instrument in a tension range.
US11154369B2 Environmental mapping for robotic assisted surgery
A system and method of use thereof are provided for dynamically generating an environmental map for use in robotic assisted surgery. The generated environmental map is used to plan a recovery tool path that an end-effector tool can safely and efficiently follow to re-position the tool back to a cutting position following the displacement of the tool from the cutting position. Additionally, the environmental map is used to update a virtual representation of a bone to provide a user with visual feedback as to the progression of the end-effector tool as the tool removes material from the bone during a surgical procedure.
US11154367B2 Robotic devices and systems for performing single incision procedures and natural orifice translumenal endoscopic surgical procedures, and methods of configuring robotic devices and systems
Example embodiments relate to devices, systems, and methods for performing a surgical action. The system may include a port assembly and instrument arm assembly. Port assembly includes proximal and distal ends, central access channel, and anchor ports formed at the distal end of the port assembly. Instrument arm assembly is configurable to be inserted through the central access channel and secured to an anchor port in a reverse-directed configuration. Instrument arm assembly includes an instrument arm and securing portion. Instrument arm includes a serially connected arrangement of a shoulder section, first arm section, elbow section, second arm section, wrist section, and end effector. Securing portion is an elongated member having proximal and distal ends. Distal end of the securing portion is securable to the shoulder section. Proximal end of the securing portion is for guiding the instrument arm assembly through the central access channel of the port assembly.
US11154360B2 Device and method for in vivo detection of clots within circulatory vessels
A device and method of using the device to detect the presence and composition of clots and other target objects in a circulatory vessel of a living subject is described. In particular, devices and methods of detecting the presence and composition of clots and other target objects in a circulatory vessel of a living subject using in vivo photoacoustic flow cytometry techniques is described.
US11154355B2 Bendable catheter arms having varied flexibility
In various embodiments, a catheter comprising an expandable electrode assembly or basket is provided. In specific embodiments, the basket is particularly useful for mapping electrical activity at one or more locations within the heart. The basket can comprise a plurality of bendable or deflectable arms. At least one of the arms may have varied flexibility over its length in the form of one or more discontinuities of stiffness or flexibility at an elbow region or other variances in flexibility over the arm's length. Such variance in flexibility may allow the arm to assume a different bent configuration or respond to external factors more positively than possible with an arm having a static or near static flexibility or stiffness over its length.
US11154353B2 Neuromodulation catheters having jacketed neuromodulation elements and related devices, systems, and methods
A neuromodulation catheter in accordance with a particular embodiment includes an elongate shaft and a neuromodulation element operably connected to the shaft. The shaft includes a proximal hypotube segment at its proximal end portion and a jacket disposed around at least a portion of an outer surface of the hypotube segment. The jacket may be made at least partially of a polymer blend including polyether block amide and polysiloxane. The neuromodulation element includes a distal hypotube segment and a tubular jacket disposed around at least a portion of an outer surface of the distal hypotube segment. The jacket has reduced-diameter segments spaced apart along its longitudinal axis. The neuromodulation element further includes band electrodes respectively seated in the reduced-diameter segments and respectively forming closed loops extending circumferentially around the jacket.
US11154352B2 Power controlled short duration ablation with varying temperature limits
Apparatus, consisting of a probe with a temperature sensor and a transducer in contact with a living subject's tissue. A power supply delivers electrical power to the transducer for tissue ablation. A controller receives a signal from the temperature sensor and in response outputs a tissue temperature. During a first time period the power supply delivers no more than a first target power to the transducer, and reduces the power when a first maximum allowable temperature of the tissue is exceeded. During a transition time period the power supply delivers no more than a second target power, while reducing the delivered power when the first maximum allowable temperature of the tissue is exceeded. During a second time period the power supply delivers no more than the second target power, while reducing the delivered power when a second maximum allowable temperature, less than the first maximum allowable temperature, is exceeded.
US11154351B2 Catheter apparatuses for modulation of nerves in communication with the pulmonary system and associated systems and methods
Devices and systems for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. The therapeutic assembly is configured for delivery within a blood vessel. The therapeutic assembly can include a pre-formed shape and can be transformable between a substantially straight delivery configuration; and a treatment configuration having the pre-formed helical shape to position the therapeutic assembly in stable contact with a wall of the body vessel. The therapeutic assembly can also include a mechanical decoupler operably connected to the therapeutic assembly that is configured to absorb at least a portion of a force exerted on the therapeutic assembly by the shaft so that the therapeutic assembly maintains a generally stationary position relative to the target site.
US11154346B2 Firing and lockout assembly for knife for electrosurgical shears
A surgical instrument includes an end effector, a handle assembly, and a knife drive assembly. The end effector includes a first jaw, a second jaw, a knife, and an electrode assembly. The handle assembly includes a housing, and an arm. The arm may pivot the second jaw between the open position and the closed position. The knife drive assembly includes an input assembly, and output assembly coupled with the knife, and a compound pulley assembly. The compound pulley assembly includes a pair of pulley wheels each having an input track, an output track, an input cable, and an output cable. The input assembly can drive the input cable a first proximal distance in order to rotate the pair of pulley wheels in a first angular direction, thereby driving the output cable a first distal direction to actuate the knife from the pre-fired position toward the fired position.
US11154345B2 System and method for tissue sealing
An electrosurgical system includes an energy source adapted to supply energy to tissue. The energy source includes a microprocessor configured to execute a tissue treatment algorithm configured to control the supply of electrosurgical energy to tissue and process a configuration file including at least one parameter of the tissue treatment algorithm. The at least one parameter is adjustable to effect a tissue seal result. The microprocessor generates a target impedance trajectory based on at least one parameter of the tissue treatment algorithm and is further configured to drive tissue impedance along the target impedance trajectory by adjusting the supply of energy to tissue to substantially match tissue impedance to a corresponding target impedance value. The system also includes an electrosurgical instrument including at least one active electrode adapted to apply electrosurgical energy to tissue.
US11154341B2 Staple and plate hard tissue fixation
A hard tissue fixation staple-plate interlocking device can include a recess in a staple body or a plate. The device can also include a locking part of the other of the staple body or plate. The device can be reconfigurable between an insertion configuration and an interlocked configuration. In the insertion configuration, the locking part can slide into the recess in a translation sliding motion that is parallel to a sliding motion of the legs of the staple, as the legs of the staple slide through the holes in the plate. In the interlocked configuration, the locking part can be at least partially in the recess, and recess surface portions can engage part surface portions and inhibit movement of the staple and plate out of the interlocked configuration. Also, multiple staples and screws can be interlocked with the plate, with staples being at non-parallel angles to each other.
US11154336B2 Retractor/compression/distraction system
A minimally invasive system for retraction, compression and distraction includes a tap having a shaft with threads and a head, a blade having a proximal end and a distal end and a base removably mountable to the proximal end. The tap is configured to form screw threads in a bone. The distal end is mountable to the head. The blade is pivotable relative to the head in a mounted configuration. The blade is configured to facilitate soft tissue retraction in the mounted configuration. The base is configured to manipulate the blade to retract and compress segments of the bone. The base is configured to provide distraction and/or compression using the provisional taps either directly or through the use of blades, insertion devices or tubes. The blades may be used to retract tissue and provide a visual field either independent or in conjunction with the provisional taps, insertion devices or tubes.
US11154334B2 Polyaxial bone anchoring device with enlarged pivot angle
A bone anchoring device includes a bone anchoring element with a spherical segment-shaped head, a receiving part configured to couple a rod to the bone anchoring element, and having a top end, a bottom end, a first passage at the bottom end with a first longitudinal axis, and a second passage at the top end with a second longitudinal axis that intersects the first longitudinal axis, a compression element, and a locking element. The receiving part also has a recess for the rod, the recess extending from the top end towards the bottom end and having a bottom that extends along an axis that is perpendicular to the second longitudinal axis. The receiving part or the compression element further has a seat. The compression element is configured to move along the first longitudinal axis while the locking element is configured to move along the second longitudinal axis.
US11154329B2 Semi-constrained anchoring system
Systems, devices, and associated methods for correcting spinal column deformities that help minimize a number of attachment anchors utilized for correction, facilitate use of straight or contoured rods, and/or help promote a more natural, physiologic motion of the spinal column.
US11154327B2 Vaginal surgical apparatus
This invention relates generally to a medical device, and more specifically, to a vaginal surgical apparatus. In one embodiment, an apparatus includes, a vaginal manipulator probe that is at least partly insertable into a vagina, the vaginal manipulator probe including an end portion that includes a bullous tip and that includes a space that accommodates a cervix therewithin; and at least one prominence incorporated with the vaginal manipulator probe operable to assist with identifying one or more positions of at least one anatomical structure or orienting the vaginal manipulator probe.
US11154326B2 Methods and devices for sonographic imaging
The present invention comprises methods and devices for providing contrast medium for sonography of structures such as ducts and cavities. The invention provides for creation of detectable acoustic variations between two generated phases of a gas and a liquid to make a contrast medium. Sonography is the primary means of imaging but other conventional detection means may also be employed with the present invention.
US11154320B2 Cutting balloon basket
A cutting balloon catheter including a balloon mounted on a distal portion of a catheter shaft. An expandable frame may be disposed over the balloon. The expandable frame may include a plurality of struts extending from a proximal end region to a distal end region. One or more cutting members may be secured to the expandable frame.
US11154317B2 Rongeur with cutting implement that is selectively driven by a motor so the cutting implement performs either power assisted or manual cutting of tissue
A rongeur cutting system and method of operating said system. The rongeur cutting system may comprise a cutting unit that includes an outer tube and a cutting implement capable of both oscillation and longitudinal movement within the outer tube. The rongeur cutting system may also comprise a handpiece including a power source and spindle for actuating the cutting implement. The spindle is designed to allow the cutting implement to oscillate while simultaneously moving longitudinally relative to the spindle. The handpiece may further comprises an advancement and retraction assembly that selectively displaces the cutting implement so the distal end of the cutting implement can be advanced towards and retracted away from the distal end of the outer tube. The method of operating the rongeur cutting system may comprise manually operating the system to move the cutting implement longitudinally while periodically actuating the power source to simultaneously oscillate the cutting implement.
US11154313B2 Vibrating guidewire torquer and methods of use
The invention provides a method of intravascular intervention that includes inserting a guidewire comprising an extended body into a lumen within tissue of a patient, advancing the guidewire into a chronic total occlusion, vibrating a proximal end of the guidewire with a mechanical vibrator, and crossing the chronic total occlusion while a distal end of the guidewire is vibrating.
US11154305B2 Patient specific surgical guide locator and mount
A resection guide locator includes a bone engagement portion with surfaces that are complementary to the surface topographies of a bone to be resected during surgery. A housing includes a socket defined by a resilient annular wall that is sized and arranged so to accept a resection guide by press-fit to thereby position and hold the resection guide within he socket. The resection guide is maintained in a predetermined, preferred position while the surfaces are releasably locked in position on the bone. A method is disclosed for forming and using the resection guide locator.
US11154302B2 Aneurysm occlusion device
An occlusion device suitable for endovascular treatment of an aneurysm in a blood vessel in a patient, including a substantially tubular structure having a proximal end region and a distal end region, having a first, expanded condition and a second, collapsed condition. The device has dimensions in the second, collapsed condition suitable for insertion through vasculature of the patient and through a neck of the aneurysm. The device further includes a control ring having a substantially annular body disposed on the proximal end region of the structure and at least substantially circumscribing the proximal end region to prevent radial expansion of the proximal end region and to provide an engagement feature during manipulation of the occlusion device.
US11154300B2 Surgical instrument comprising separate tissue securing and tissue cutting systems
A surgical instrument is disclosed which comprises a staple firing system and a tissue cutting system. In various instances, the instrument is configured to prevent the tissue cutting system from being operated before the staple firing system has been fully actuated. In certain instances, the instrument is configured to prevent the tissue cutting system from being operated before the staple firing system has been actuated to sufficiently deform the staples.
US11154299B2 Stapling assembly comprising a firing lockout
A stapling assembly comprising a first jaw, a second jaw, an elongate channel configured to receive a staple cartridge, a firing member, a biasing member, and a lock member movable between locked and unlocked positions is disclosed. One of the first jaw and the second iaw is movable relative to the other of the first jaw and the second jaw between an open position and a closed position. The staple cartridge comprises staples and a sled configured to be advanced by the firing member during a firing stroke. The firing member comprises a cutting edge, a first camming member configured to engage the first jaw during the firing stroke, and a second camming member configured to engage the second jaw during the firing stroke. The firing member is prevented from performing the firing stroke when the stapling assembly is in one of a plurality of lockout states.
US11154298B2 Stapling system for use with a robotic surgical system
A stapling system for use with a robotic surgical system is disclosed. The stapling system comprises a housing removably attachable to the robotic system, a plurality of rotatable inputs rotatably supported in the housing, and an end effector comprising first and second jaws. The first jaw is movable relative to the second jaw between an open position and a closed position. A tissue gap is defined between the first jaw and second jaws when the first jaw is in the closed position. The stapling system further comprises a pre-clamping member, a dynamic clamping member, a first rotary drive, and a second rotary drive. The first rotary drive is coupled to the pre-clamping member and is actuable to move the first jaw into the closed position and move the first jaw into the open position. The second rotary drive is coupled to the dynamic clamping member.
US11154296B2 Anvil layer attached to a proximal end of an end effector
An anvil-attachable layer for use with a surgical stapler, or fastening instrument, wherein a proximal end portion of the layer is attached to a staple cartridge assembly, for example. The layer may be attached to the staple cartridge assembly by an adhesive, weld, or a staple-cartridge-based clamp, wherein the attachment is weak enough to allow the layer to pull away from the staple cartridge assembly with stapled tissue. Alternatively, the layer can include two or more lateral slits that define a connector region that can be cut by a knife of a surgical stapler to release the layer.
US11154291B2 Surgical medical suture needle with surgical suture and anchor system
A cervical retraction system includes a suture having a first end and a second end, a cervical anchor secured to the first end of the suture and a curved needle secured to the second end of the suture. A method of retracting a cervix includes providing the cervical retraction system, inserting the curved needle through tissue of a cervix of a patient, advancing the needle along a trajectory of a curve of the needle until it emerges through an external os of the cervix and applying counter tension by pulling the needle out through the external os.
US11154290B2 Dual expansion anchor
A bone anchor, including: a bone engaging member including: a first proximal bone engaging portion and a second distal bone engaging portion; and an expansion feature configured to allow radial expansion of the first bone engaging portion and the second bone engaging portion; an expander having a first proximal expansion portion and a second distal expansion portion and displaceable between a first position relative to the bone engaging member and a second position relative to the bone engaging member; a tissue capture feature; and wherein the first expansion portion of the expander is configured to expand the first bone engaging portion of the bone engaging member and the second expansion portion of the expander is configured to expand the second bone engaging portion of the bone engaging member when the expander is in the second position.
US11154288B1 Method and apparatus for performing spinal fusion surgery
Implants, instruments, and methods for performing surgical procedures on the spine, including one or more of creating an operative corridor to the spine, delivering implants to the spine, fusing one or more segments of the spine and fixing one or more segments of the spine.
US11154285B2 Laparoscopic port site closure tool
A device is provided to assist in closing an incision through body tissue that comprises a tubular body sized for introduction through the incision and carrying a plurality of stabilizer elements at the distal end thereof. The stabilizer elements are configured to be deployed within the body cavity to engage the lowermost tissue layer. In one method, the device is pulled with the stabilizer elements deployed to retract the body tissue away from adjacent body structure. In another method, a plurality of needle tips carrying sutures are guided through the body tissue to a retention device at the ends of the stabilizer elements. With the needle tips captured in the retention devices, the device is withdrawn from the incision so that the sutures form ligatures that can be tied off to close the incision.
US11154284B2 Occlusion device for closing anatomical defects
An occlusion device for closing an anatomical defect in tissue comprising a conduit connecting an opening on a first tissue and an opening on a second tissue is provided. The occlusion device comprises a scaffold comprising a) a proximal support structure comprising at least two arms; b) a distal support structure comprising at least two arms, wherein the arms are adapted to provide anchorage for the device in the tissue; and c) a waist portion adapted for extending through the opening on the first tissue and connecting the proximal support structure with the distal support structure, wherein the scaffold consists essentially of a biodegradable polymer, wherein the proximal support structure and the distal support structure comprise or consist of polycaprolactone (PCL), poly-(D,L-lactide-co-caprolactone) (PLC), or a mixture thereof. A method of closing an anatomical defect using the occlusion device is also provided.
US11154278B2 Ultrasound signal processing device, ultrasound diagnostic device, and ultrasound signal processing method for calculating blood flow and tissue information
An ultrasound signal processing device that generates, for each detection wave, a first complex Doppler signal sequence through quadrature detection of a reception signal sequence; generates tissue velocity data by calculating velocity values for each set of coordinates of observation points in a region of interest from the first complex Doppler signal sequence; generates a second complex Doppler signal sequence by performing clutter removal filter processing on the first complex Doppler signal sequence; generates first velocity data by calculating velocity values for each set of coordinates of the observation points from the second complex Doppler signal sequence; and generates, for each set of coordinates of the observation points, second velocity data based on the first velocity data and the tissue velocity data, and third velocity data by applying a correction to velocity values of the second velocity data that have an absolute value equal to or less than a threshold.
US11154277B2 Tissue viscoelastic estimation from shear velocity in ultrasound medical imaging
For viscoelastic estimation with ultrasound, shear wave speed is measured for different locations in a region of interest. For each location, the shear wave speed is estimated without frequency band division. A distribution of shear wave speeds in the region of interest is matched a modeled distribution corresponding to a particular value of the viscoelastic property.