最新美国发明专利第2021-10-05期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US11136592B2	CMV resistance allele The present invention relates to an allele designated alpha-CMV which confers resistance to CMV when present in a spinach plant, wherein the protein encoded by said allele is a CC-NBS-LRR protein that comprises in its amino acid sequence: a) the motif “MAEIGYSVC” (SEQ ID NO: 22) at its N-terminus; and b) the motif “KWMCLR” (SEQ ID NO: 23); and c) an LRR domain that has in order of increased preference at least 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 10. The allele has a genomic nucleotide sequence which in order of increased preference has at least 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100% sequence similarity to SEQ ID NO: 1. The invention further relates to plants comprising the allele and to various methods involving the allele.
US11136591B2	Plant cells and plants modified to increase resistance to necrotrophs or drought and methods of selecting and using the same The invention generally relates to plant cells and plants modified to increase resistance to necrotrophs or drought and methods of selecting and using the same. More specifically, the invention relates in part to plant cells and/or plants modified to eliminate or reduce as compared to control plants cell the NADPH oxidase activity or expression of certain respiratory burst oxidase homolog (RBOH) proteins and methods of selecting for and using the same.
US11136580B2	SMN2 element 1 antisense compositions and methods and uses thereof The invention provides methods and compositions for treatment of spinal muscular atrophy (SMA). In one aspect of the invention, a series of compositions comprising an antisense oligonucleotide targeting the Element 1 site on the SMN2 pre-mRNA and a Morpholino backbone is disclosed. In another aspect of the invention, a method of treating SMA patients by modulating the splicing of SMN2 pre-mRNA to increase the amount of full-length SMN is disclosed. Certain embodiments of the inventive method comprise administering an E1-targeting antisense oligonucleotide, such as Morpholino based antisense oligonucleotide, to a SMA subject.
US11136577B2	Methods and compositions for inhibiting PMP22 expression The present embodiments provide methods, compounds, and compositions useful for inhibiting PMP22 expression and for treating, preventing, or ameliorating a disease associated with PMP22.
US11136575B2	TCR libraries The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain comprising an alpha chain variable domain and a beta chain comprising a beta chain variable domain and the library comprises more than one TRAV gene product and/or more than one TRBV gene product, wherein the beta chain variable domain does not comprise one or more of a TRBV5-1, 5-3, 5-4, 5-5, 5-6, 5-7 or 5-8 gene product and wherein the plurality of TCRs do not consist essentially of TCRs comprising a TRAV12-2 gene product from a natural repertoire and a TRBV6 gene product from a natural repertoire and TCRs comprising a TRAV21 gene product from a natural repertoire and a TRBV6 gene product from a natural repertoire.
US11136570B2	Antimicrobial fusion proteins comprising an endolysin and an amphipathic peptide segment The present invention relates to antimicrobial agents against Gram-positive bacteria, in particular to fusion proteins composed of an enzyme having the activity of degrading the cell wall of Gram-positive bacteria and an additional peptide stretch fused to the enzyme at the N- or C-terminus. Moreover, the present invention relates to nucleic acid molecules encoding said fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, the present invention relates to said fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-positive bacterial infections, as diagnostic means or as cosmetic substance. The present invention also relates to the treatment or prevention of Gram-positive bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries. Further, the present invention relates to a pharmaceutical composition comprising said fusion protein.
US11136568B2	Pullulanase variants and polynucleotides encoding same The present invention relates to pullulanase variants comprising substitutions of the parent pullulanase at one or more positions corresponding to positions 393, 143, 150, 243, 244, 345, 346, 368, 370, 373, 381, 382, 385, 387, 402, 429, 430, 431, 432, 456, 486, 492, 610, 624, 631, 632, 665 and 699 of the polypeptide of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
US11136567B2	CRISPR/CPF1 systems and methods This invention pertains to recombinant AsCpf1 and LbCpf1 nucleic acids and polypeptides for use in CRISPR/Cpf1 endonuclease systems and mammalian cell lines encoding recombinant AsCpf1 or LbCpf1 polypeptides. The invention includes recombinant ribonucleoprotein complexes and CRSPR/Cpf1 endonuclease systems having a suitable AsCpf1 crRNA is selected from a length-truncated AsCpf1 crRNA, a chemically-modified AsCpf1 crRNA, or an AsCpf1 crRNA comprising both length truncations and chemical modifications. Methods of performing gene editing using these systems and reagents are also provided.
US11136564B2	Modified polymerases for improved incorporation of nucleotide analogues The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogues bearing substituents at the 3′ position of the sugar moiety that are larger in size than the naturally occurring 3′ hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of DNA sequencing.
US11136559B2	Engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same The invention generally relates to engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same. More specifically, the invention relates in part to compositions including engineered prephenate dehydrogenases (PDH) polypeptides and engineered arogenate dehydrogenase (ADH) polypeptides with altered substrate preferences and tyrosine sensitivities and methods of using the same.
US11136558B2	Compositions and methods for reducing fucosylation of glycoproteins in insect cells and methods of use thereof for production of recombinant glycoproteins Compositions for reducing fucosylation of glycoproteins in insect cells are provided. Also disclosed are methods of use of such compositions for the production of recombinant humanized proteins.
US11136555B2	Compositions and methods for differentiation of human pluripotent stem cells into desired cell types In related-art methods of differentiating pluripotent stem cells into a desired cell type, there has not been established a differentiation induction method using human ES/iPS cells and being stable and highly efficient. The use of complicated culture steps is a large problem. In addition, there are also large problems in, for example, that the speed of cell differentiation is low, and hence long-period culture is required, and that the differentiation efficiency is low, and hence it is difficult to obtain a sufficient number of required cells. A method of inducing differentiation into a desired cell type, which induces differentiation within a short period of time and with high efficiency by the use of a Sendai virus vector capable of expressing a transcription factor, and as required, the use of a pluripotent stem cell in which an expression amount of a POU5F1 protein has been substantially removed or reduced, is provided.
US11136554B2	Methods of reprogramming cells The present invention provides methods of reprogramming cells, for example, directly reprogramming a somatic cell of a first cell type into a somatic cell of a second cell type, are described herein. In particular, the present invention generally relates to methods for reprogramming a cell of an endoderm origin to a cell having pancreatic β-cell characteristics. The present invention also relates to an isolated population comprising reprogrammed cells, compositions and their use in the treatment of diabetes mellitus. In particular, the present invention relates to reprogramming a cell of an endoderm origin to a cell having pancreatic β-cell characteristics by increasing the protein expression of at least one transcription factor selected from Pdx1, Ngn3 or MafA in the cell of endoderm origin to reprogram the cell of an endoderm cell to a cell which exhibits at least one or at least two characteristics of an endogenous pancreatic β-cell.
US11136550B2	Method and system for tissue treatment with critical/supercritical carbon dioxide Methods of decontaminating bone tissue and an apparatus or system for the same are provided. The methods can be multi-batch processes and include contacting the bone tissue having contaminants with carbon dioxide to decontaminate the bone tissue and to form carbon dioxide having contaminants. The contaminated carbon dioxide is collected and the contaminants are removed to obtain purified carbon dioxide which can be recycled to treat contaminated bone tissue. The contaminated carbon dioxide can be purified by bubbling it through water and/or an organic solvent followed by acid treatment, filtering and liquefying the carbon dioxide. Contaminants that can be removed from contaminated bone tissue, and in turn, from contaminated carbon dioxide include infectious organisms, bacteria, viruses, protozoa, parasites, fungi and mold or a mixture thereof.
US11136546B2	Recombinant Escherichia coli and application of the same Disclosed in the present invention is a recombinant Escherichia coli and application thereof. The recombinant Escherichia coli was deposited on Aug. 28, 2018 in the China General Microbiological Culture Collection Center with the preservation number CGMCC No. 16349. The recombinant Escherichia coli is fermented and cultured, and the concentration of Microcin J25 in the supernatant can reach 4000 mg/L or more.
US11136531B2	Cleaning system for a printing press recirculation system A cleaning system is provided for a printing press recirculation system, in which the cleaning system generates a plurality of bubbles within a fountain solution of the printing press recirculation system. The cleaning system includes (i) a first composition comprising a solid blend including (a) a first alkaline cleaning agent having a first alkaline strength, (b) a detergent salt, (c) a non-foaming emulsifying agent, and (d) a second alkaline cleaning agent having a second alkaline strength, in which the first alkaline strength is greater than the second alkaline strength; (ii) a second composition comprising one or more organic acids. Also provided are methods of cleaning a printing press recirculation system.
US11136522B2	Azole derivatives as lubricating additives Lubricating compositions comprising an azole-acrylic adduct formed by contacting an azole compound with an acrylic. The adduct formed has at least one nitrogen-alkyl group comprising at least one acyl. The lubricating composition also comprises an antiwear agent and an antioxidant. Methods of lubricating an internal combustion engine comprising contacting the internal combustion engine with the lubricating composition comprising an azole-acrylic adduct formed by contacting an azole compound with an acrylic. Methods of reducing corrosion and/or seal deterioration in an internal combustion engine. The use of an azole-acrylic adduct in a lubricating composition to reduce corrosion and/or seal deterioration in an internal combustion engine.
US11136518B2	Clean gasoline from a light hydrocarbon fraction and preparation method thereof A method for producing a clean gasoline from a light hydrocarbon fraction is disclosed. The method includes two main steps including desulfurization of a light hydrocarbon fraction along with enhancing octane number of the desulfurized light hydrocarbon fraction. The octane number of the desulfurized hydrocarbon fraction is enhanced by applying a hormone-modified additive.
US11136516B2	Motor gasoline with improved octane and method of use Provided are octane enhancing additives and methods that improve a liquid fuel composition's octane rating. A liquid fuel composition may comprise a liquid fuel and an octane enhancing additive. The octane enhancing additive may comprise an indoline compound with a bicyclic ring structure, wherein the indoline compound comprises a six-membered aromatic ring and a five-membered aliphatic ring that share a carbon-carbon aromatic bond. The five-membered aliphatic ring may be heterocyclic and may comprise a nitrogen positioned in an alpha position to the six-membered aromatic ring.
US11136515B2	Temperature profile in an advanced thermal treatment apparatus and method Applying heat from a heat source to a first region to cause a first pyrolysis process, the first pyrolysis process resulting in a gaseous mixture, and applying heat from the heat source to a second region to cause a second pyrolysis process, the second pyrolysis process being applied to the gaseous mixture, wherein the second region is located closer to the heat source than the first region. Pyrolysis is used to destroy oils, tars and/or PAHs in carbonaceous material.
US11136513B2	Multi-stage device and process for production of a low sulfur heavy marine fuel oil from distressed heavy fuel oil materials A multi-stage process for reducing the production of a Product Heavy Marine Fuel Oil from Distressed Fuel Oil Materials (DFOM) involving a pre-treatment process that transforms the DFOM into Feedstock HMFO which is subsequently sent to a Core Process for removing the Environmental Contaminates. The Product Heavy Marine Fuel Oil complies with ISO 8217 for residual marine fuel oils and has a sulfur level has a maximum sulfur content (ISO 14596 or ISO 8754) between the range of 0.05 mass % to 1.0 mass. A process plant for conducting the process is also disclosed.
US11136502B2	Method of producing thiogallate-based fluorescent material, method of producing light-emitting device, thiogallate-based fluorescent material and light-emitting device Provided are a method of producing a thiogallate-based fluorescent material, a method of producing a light-emitting device, a thiogallate-based fluorescent material, and a light-emitting device. The method of producing a thiogallate-based fluorescent material includes preparing a first solution containing at least one M1 ion selected from the group consisting of Sr, Be, Mg, Ca, Ba and Zn, and at least one M2 ion selected from the group consisting of Eu and Ce, and a second solution containing a sulfite ion, simultaneously supplying the first solution and the second solution to a reactor to obtain a powder containing a sulfite that contains an element M1 and an element M2, mixing a raw material that contains the powder containing the sulfite that contains the element M1 and the element M2 and a powder containing a gallium compound, with lithium chloride to obtain a mixture, and heat-treating the mixture to obtain a thiogallate-based fluorescent material.
US11136500B2	Luminescent particle and compound An object of the present invention is to provide a luminescent particle having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield; and a compound having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield in the particles. According to the present invention, provided is a luminescent particle containing at least one kind of compound represented by Formula (1) (definitions of substituents in the formula are as set forth in the description) and a particle.
US11136499B2	Aqueous composition containing suspended ZnO particles The invention relates to an aqueous composition comprising a suspension of ZnO particles and a polymer stabiliser containing carboxylic acid functions and carboxylic acid salt functions.
US11136494B2	Polymer with internal crosslinking and breaking mechanisms A polymer composition may include one or more monomeric units, with an internal crosslinker, internal breaker, scale control additive or a combination thereof.
US11136479B2	Electrically conductive adhesive film and dicing-die bonding film using the same The electrically conductive adhesive film comprises a metal particle (P), a resin (M) and a prescribed sulfide compound (A), the resin (M) comprises a thermosetting resin (M1), and the metal particle (P) has an average particle size (d50) of 20 μm or less and comprises 10% by mass or more of a first metal particle (P1) having a fractal dimension of 1.1 or more when viewed in a projection drawing in a primary particle state.
US11136477B2	Hand wrap for musical instrument An apparatus, comprising; a piece of material having a first end and a second end and a first side and second side, wherein the piece of material has a predetermined length and width of approximately, an adhesive member having a first side and a second side, wherein each side has adhesive properties, and the adhesive member is attached distal to the first end of the piece of material on the first side, a removable cover, detachably secured to the adhesive member exposed side, and at least one tie attached to the to the second end of the piece of material.
US11136475B2	Articles and components with UV radiation curable elastomeric materials and methods of making the same A method of manufacturing an article that includes providing an element formed of an elastomeric material or composite; placing the surface of the element in contact with a substrate; and affixing the element to the substrate. The element includes an uncured, partially cured, or fully cured UV radiation curable elastomeric material and optionally one or more regions of an adhesive material. The element is affixed to the substrate while the surface of the element is in contact with a surface of the substrate by increasing a temperature of at least a portion of the element, applying pressure to at least a portion of the element, or exposing the uncured or partially cured UV radiation curable material to UV radiation in an amount and for a duration of time that is sufficient to partially cure the uncured material or to fully cure the partially cured material.
US11136474B2	Polishing liquid and polishing method A polishing liquid for polishing a surface to be polished containing a tungsten material, the polishing liquid comprising abrasive grains; a polymer having a cationic group at the terminal; an oxidizing agent; a metal oxide-dissolving agent; and water, in which the polymer has a structural unit derived from an unsaturated carboxylic acid, a weight average molecular weight of the polymer is 20000 or less, and a pH is less than 5.0.
US11136472B2	Multilayer decorative coating composition with low discolouration A coating composition including at least one water-based anionic polyurethane dispersion and 0.1 to 4 weight-% of nanoparticulate TiO2 having an average particle size of not more than 100 nm, based on the solids content of the coating composition. The cured coating composition is suitable as a top coat in a decorative multilayer coating system including at least one polyurethane base coat. The multilayer coating system exhibits improved non-yellowing property and cleanability. The liquid multilayer coating system is particularly suitable for balcony applications.
US11136471B2	UV curable coating composition Provided is a UV curable coating composition, and more particularly, to a UV curable coating composition including: at least one polyfunctional epoxy oligomer; at least one epoxy compound; at least one non-hydrolyzed epoxy silane; at least one polyfunctional acrylic compound; at least two photoinitiators; and at least one surfactant. The UV curable coating composition according to the present invention can be coated on various substrates and provide excellent adhesion and scratch resistance to the coating layer regardless of a substrate type unlike conventional coating compositions.
US11136467B2	Thermal substrate with high-resistance magnification and positive temperature coefficient A printed circuit that comprises a substrate, electrical interconnects and a double-resin ink having a positive temperature coefficient (PTC), wherein the double-resin ink has a resistance magnification of at least 20 in a temperature range of at least 20 degrees Celsius above a switching temperature of the double-resin ink, the resistance magnification being defined as a ratio between a resistance of the double-resin ink at a temperature ‘T’ and a resistance of the double-resin ink at 25 degrees Celsius. The substrate is a fabric or mesh, while the double-resin ink and the electrical interconnects are deposited onto the substrate.
US11136466B2	Inkjet inks Yellow inkjet inks are disclosed. In an example, an inkjet ink composition comprises: at least one colorant comprising at least one yellow pigment; at least one solvent comprising at least one triol; water; and at least one binder. The binder comprises a polyurethane-based binder dispersion, which comprises water and a polyurethane. The polyurethane comprises: (A) a polyisocyanate, (B) a first polyol having a chain with two hydroxyl functional groups at one end of the chain and no hydroxyl groups at an opposed end of the chain, (C) a second polyol having a chain with two hydroxyl functional groups at both ends of the chain, (D) a carboxylic acid functional group with two hydroxyl functional groups, and (E) a sulfonate or sulfonic acid functional group having two amino functional groups.
US11136464B2	Articles subject to ice formation comprising a repellent surface Articles subject to ice formation during normal use are described. The article comprises a repellent surface such that the receding contact angle of the surface with water ranges from 90 degrees to 135 degrees. The repellent surface comprises a fluorochemical material, typically in combination with a non-fluorinated organic polymeric binder. The fluorochemical material is preferably a compound having the formula: (Rf−L−P)nA Rf is a fluorinated group; L is independently an organic divalent linking group; P is a catenary, divalent heteroatom-containing carbonyl moiety, such as —C(O)O—; A is hydrocarbon moiety; and n typically ranges from 1 to 3; also described are methods of making an article comprising providing an article subject to ice formation during normal use and providing a liquid repellent surface, as described herein, on at least a portion of the article.
US11136463B2	One-component aqueous coating compositions containing polyurethane and phyllosilicates for oxygen barrier coatings Described is an aqueous one-component coating composition comprising dispersed polyurethane and phyllosilicate. The polyurethane carries acid groups which are at least partially neutralized with a hydrophilic base selected from inorganic bases and organic mono-amines. The hydrophilic base has a water solubility at 20° C. of at least 150 g/l, preferably of at least 200 g/l. The composition can be used for providing oxygen barrier properties to a polymer film.
US11136461B2	Degradable composite structures Embodiments may generally take the form of a degradable composite structure and a method for controlling the rate of degradation of a degradable composite structure. An example embodiment may take the form of a degradable polymer matrix composite (PMC) including a matrix having: a degradable polymer, a fiber reinforcement, and particulate fillers. The fiber loading is between approximately 10% to 70% by weight and the particulate loading is between approximately 5% to 60%.
US11136459B2	Viscoelastic conductive nanomaterial-polymer nanocomposites and sensing devices comprising the composite material A homogenous composite material with increased tensile strength comprising 2-dimensional nano-sheets exfoliated from a 3-dimensional layered material mixed in a liquid non-Newtonian viscoelastic material to produce the homogenous composite material; and a process for making the same.
US11136458B2	Thermally stable and electrically isolating barrier film A thermoset barrier film including: a reaction product of the formulas (I), (II), (III), (IV), or a mixture thereof, as defined herein. Also disclosed are methods of making and using the thermoset barrier film, and devices incorporating the thermoset barrier film.
US11136456B2	Thermoplastic resin composition and article produced therefrom A thermoplastic resin composition and a molded article formed of the same. The thermoplastic resin composition includes: a polycarbonate resin; an aromatic vinyl copolymer resin; mica having an average particle diameter of about 200 μm to about 400 μm; a modified polyolefin; and a phosphorus flame retardant, wherein the modified polyolefin includes a first modified polyolefin including a repeat unit represented by Formula 1 and a repeat unit represented by Formula 2 as defined in the specification and a second modified polyolefin including the repeat unit represented by Formula 1 and a repeat unit represented by Formula 3 as also defined in the specification. The thermoplastic resin composition can have good properties in terms of rigidity, impact resistance, heat resistance, flame resistance, and balance therebetween.
US11136455B2	Resin composition and molded product manufactured therefrom Provided are resin composition and a molded product manufactured therefrom. The resin composition includes (A) a polycarbonate resin; (B) a rubber-modified vinyl-based graft copolymer; (C) a rubber-modified vinyl-based copolymer; (D) a vinyl-based copolymer including an epoxy group; and (E) a compound represented by Chemical Formula 1. (R1)a(R2)b(R3)c—Si—(OR4)4-a-b-c [Chemical Formula 1] In Chemical Formula 1, each substituent is the same as that defined in the specification.
US11136451B2	Aqueous binder compositions An aqueous binder composition is disclosed that comprises at least one long-chain polyol having at least two hydroxyl groups and a number average molecular weight of at least 2,000 Daltons; a primary cross-linking agent comprising at least two carboxylic acid groups; and a secondary cross-linking agent comprising a short-chain polyol having at least two hydroxyl groups and a number average molecular weight less than 2,000 Daltons.
US11136449B2	Thermoplastic resin composition A thermoplastic resin composition of the present invention comprises: (A) 100 parts by weight of a thermoplastic resin comprising (A1) a rubber-modified aromatic vinyl-based graft copolymer, (A2) an aromatic vinyl-based copolymer resin having a flow index of about 5 g/10 min to about 8 g/10 min as measured by the ASTM D 1238 standard, and (A3) an α-methylstyrene copolymer; and (B) about 0.1 to about 10 parts by weight of zinc oxide, wherein the zinc oxide has a size ratio (B/A) of peak A in the region of 370 nm to 390 nm to peak B in the region of 450 nm to 600 nm of about 0.01 to about 1 in photoluminescence measurement, and has a BET surface area of about 10 m2/g or less as measured by a BET analyzer.
US11136448B2	Rubber composition for torsional damper and torsional damper A rubber composition for a torsional damper has (A) a minimum value of tan δ at −30° C. to 120° C. of 0.140 or more, (B) a ratio of tan δ at −30° C. to tan δ at 60° C. of 3.5 or less, and (C) a ratio of E′ at −30° C. to E′ at 60° C. of 21 or less.
US11136447B2	Polyamide resin composition and molded article containing same A polyamide resin composition includes 100 parts by weight of a polyamide resin (A), 0.1 to 50 parts by weight of a fire retardant (B), 0.001 to 1 part by weight of a metal and/or salt thereof (C), and 0.001 to 1 part by weight of a compound (D) as represented by formula [I]: QX [I] wherein in formula [I], Q represents an aromatic hydrocarbon group or an alicyclic hydrocarbon group and X represents a 5-membered heterocyclic ring group, Q and X forming a covalent bond or a fused ring.
US11136444B2	Polyurethanes having reduced aldehyde emissions Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one polyacetoacetate compound and least one antioxidant. Foams so produced emit low levels of both formaldehyde and acetaldehyde.
US11136443B2	Thermoplastic composite The invention relates to multi-layer thermoplastic composites, and in particular composites having fluoropolymer in the outer layer and a thermoplastic substrate layer. The fluoropolymer outer layer may either be a layer comprising a majority, and preferably 100 percent fluoropolymer, or may be a blend of a thermoplastic matrix with fluoropolymer at a level of from 5 to 60 weight percent, based on the total weight of all polymers. Especially useful thermoplastic matrices include acrylic polymers, and styrenic polymers, especially styrenic copolymers such as acrylonitrile/styrene/acrylate (ASA), acrylonitrile/butadiene/styrene (ABS) and styrene/acrylonitrile (SAN). While the fluoropolymer may be any fluoropolymer, thermoplastic fluoropolymers, such as polymers and copolymers of polyvinylidene fluoride are especially useful. The improved flame retardant composite of the invention is especially useful in cap layers over plastic substrates, such as for flame-retardant plastic decking, railings, posts, fencing, siding, roofing, and window profiles.
US11136442B2	Prepreg and fiber reinforced composite material The objective of the present invention is to provide a prepreg and a fiber reinforced composite material using this prepreg. This prepreg has good handleability, is suitable for producing a reinforced composite material in a short-time and without using an autoclave, and is capable of yielding a fiber reinforced composite material exhibiting excellent impact resistance, wherein the occurrence of voids has been suppressed. To attain the objective, this prepreg comprises a reinforced fiber [A] that is layered and partially impregnated with an epoxy resin composition containing an epoxy resin [B] and a hardener [C], the impregnation rate φ being 30 to 95%. In this prepreg, a thermoplastic resin [D] insoluble in the epoxy resin [B] is distributed unevenly over a surface on one side of the prepreg, and a portion not impregnated with the epoxy resin composition is localized in the layer of the reinforced fiber [A] on the side where the thermoplastic resin [D] is distributed unevenly. This prepreg has a localization parameter σ, which defines the degree of the localization to be in the range of 0.10<σ<0.45.
US11136437B2	Curable particulate silicone composition, semiconductor member comprising curable particulate silicone composition, and method for molding semiconductor member Provided is a curable particulate silicone composition that is hot-meltable, has excellent handling workability, curing properties, and gap fill properties when melted, and gives a cured product having excellent flexibility and resilience from room temperature to high temperatures of about 150° C. Also provided are pellets or the like formed by molding the curable particulate silicone composition. The curable particulate silicone composition comprises: (A) hot-meltable silicone particles that have a softening point of 30° C. or higher and have a hydrosilylatable group and/or a radical reactive group; (B) an inorganic filler (particulates) that is substantially free of coarse particles having an average particle diameter of 10.0 μm or larger; and (C) a curing agent. When cured, the composition gives a cured product having a storage modulus of 2000 Mpa or lower at 25° C. and of 100 Mpa or lower at 150° C.
US11136436B2	Method for condensation polymerization of hydroxyl-terminated polydiorganosiloxanes A method for making long chain hydroxyl terminated polydiorganosiloxanes with low cyclics content via condensation polymerization employs a selective catalyst. The catalyst includes a salt-anion complex and a free acid.
US11136435B2	Method for producing polyimide film, polyimide film, polyamic acid solution, and photosensitive composition A method for producing a polyimide film includes: obtaining a polyamic acid solution having a viscosity of 5 to 150 cps by preparing a raw material mixture liquid containing a solvent, a tetracarboxylic dianhydride represented by a specific general formula, and an aromatic diamine represented by a specific general formula, and has a total content of the tetracarboxylic dianhydride and aromatic diamine of 15% by mass or less, and reacting the tetracarboxylic dianhydride and aromatic diamine with each other in the raw material mixture liquid forming a polyamic acid having a repeating unit represented by a specific general formula; obtaining a polyimide-forming mixture liquid by adding a compound represented by a specific general formula to the polyamic acid solution; and obtaining a polyimide film represented by a specific general formula by forming a film made of the polyimide-forming mixture liquid, followed by imidization of the polyamic acid in the film.
US11136434B2	Polyamines, synthesis method thereof and use thereof for the selective elimination of H2S from a gaseous effluent comprising CO2 Polyamines of formula (I), their preparation method and their use in an absorbing solution based on amines in order to selectively eliminate H2S from a gaseous effluent containing H2S and CO2, which polyamines are obtained by a reaction between piperazine and an epihalohydrin or a 1,3-dihalo-2-propanol
US11136431B2	Crystalline thermoplastic polyurethane article The disclosed technology relates to an article, such as a hose, tube, sheet, film, or filament made from a crystalline thermoplastic polyurethane composition, wherein the crystalline thermoplastic polyurethane composition comprises the reaction product of a polyisocyanate component, a polyester polyol component, optionally a chain extender component, and optionally a catalyst. The article is produced by melt or extrusion processes.
US11136429B2	Method of making polymers A method of making a polymer having the structure (I): wherein L is a linking group, R is a hydrocarbon group or a substituted-hydrocarbon group, and x is 2 or more, preferably from 2 to 100, more preferably from 2 to 50; and wherein each {Q} is an identical polymer block or contains a plurality of polymer blocks. The method comprises reacting a di-halo initiator with a selected monomer one or more times and then reacting the resulting moiety with a dithiol compound of the structure HS—R—SH.
US11136424B2	Preparation method for fluorine- and chlorine-containing conductive polymer resin and single- or double-sided filled composite thin film prepared using same and the preparation method therefor Disclosed are a method for a preparing fluorine- and chlorine-containing conductive polymer resin, a single-side or double-side filled composite film prepared using the fluorine- and chlorine-containing conductive polymer resin, and a method for preparing the film. The fluorine- and chlorine-containing conductive polymer single-side or double-side filled composite film comprises a microporous film skeleton and the fluorine- and a chlorine-containing conductive polymer resin. The composite film is mechanically stronger, more waterproof, more impervious to water and toxic and harmful chemicals, and more moisture permeability. When applied to biochemical protective clothing, it can greatly enhance the combat effectiveness of the soldiers because it is light and more impervious to water and toxic and harmful chemicals, brings about comfort, and keeps the soldiers warm. When applied to fuel cells, it can provide better electrical properties due to its high conductivity and can allow the fuel, such as hydrogen or alcohol, to burn more completely.
US11136418B2	Method for manufacturing hydrogenated nitrile rubber A method produces a hydrogenated nitrile rubber having an iodine value of 120 or less, the method having a first coagulation step of adding a halogen atom-free metal salt as a coagulant to a nitrile rubber latex to form a nitrile rubber coagulum; a solution preparation step of dissolving the nitrile rubber coagulum in an organic solvent to prepare a nitrile rubber solution; a hydrogenation step of subjecting the nitrile rubber solution to a hydrogenation reaction to afford a hydrogenated nitrile rubber solution; and a second coagulation step of adding a divalent metal salt as a coagulant to the hydrogenated nitrile rubber solution to form a hydrogenated nitrile rubber coagulum.
US11136416B2	Rubber composition A rubber composition containing a rubber and modified cellulose fibers, wherein one or more substituents selected from substituents represented by the following general formulas (1) and (2): —CH2—CH(OH)—R1 (1), —CH2—CH(OH)—CH2—(OA)n—O—R1 (2), wherein each R1 in the general formulas (1) and (2) is independently a linear or branched alkyl group having 3 or more carbon atoms and 30 or less carbon atoms; n in the general formula (2) is a number of 0 or more and 50 or less; and A is a linear or branched, divalent saturated hydrocarbon group having 1 or more carbon atoms and 6 or less carbon atoms are bonded to cellulose fibers via an ether bond, wherein the modified cellulose fibers have a cellulose I crystal structure. The rubber composition of the present invention can be suitably used for machine tool parts, household electric appliance parts, automobile parts, and the like.
US11136413B2	PDL-1 antibody, pharmaceutical composition thereof, and uses thereof The present invention belongs to the field of tumor therapy and molecular immunology, and relates to a PDL-1 antibody, a pharmaceutical composition thereof and use thereof. In particular, the present invention relates to a PDL-1 monoclonal antibody or an antigen-binding fragment thereof, wherein the monoclonal antibody has a heavy chain variable region comprising CDRs as set forth in SEQ ID NOs: 15-17; and/or has a light chain variable region comprising CDRs as set forth in SEQ ID NOs: 18-20. The monoclonal antibody of the present invention can bind to PDL-1 specifically, and specifically remove immunosuppressive function of PDL-1 and activate T lymphocytes.
US11136412B2	Antibodies to symmetrically dimethylated arginine analytes and use thereof Disclosed is an antibody which binds to a symmetrically dimethylated arginine analyte that can be used to detect a symmetrically dimethylated arginine analyte in a sample, such as in a homogeneous enzyme immunoassay method.
US11136408B2	Anti-PD-1 antibodies, method for producing same and method for using same The present invention relates to biotechnology and comprises isolated monoclonal antibodies, in particular human monoclonal antibodies, which specifically bind to PD-1 with high affinity. The antibodies according to the invention may be chimeric, humanized or human antibodies, or antigen-binding fragments thereof, and may be used as a medicinal agent in oncology and immuno-oncology, for treating diseases associated with various cell proliferation or development disorders. The invention also relates to methods for producing said antibodies and a method for treating human diseases using said antibodies.
US11136405B2	BAFF-R antibodies and uses thereof Provided herein are BAFF-R antibodies as well as compositions and methods of making and using the same. The antibodies provided herein are, inter alia, useful for the treatment of cancer and autoimmune diseases.
US11136404B2	Anti-OX40 antibodies The present disclosure provides antibodies that specifically bind to human OX40 receptor (OX40) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human OX40 and modulate OX40 activity, e.g., enhance, activate, or induce OX40 activity, or reduce, deactivate, or inhibit OX40 activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., enhances, activates, or induces OX40 activity. Also provided are methods for treating autoimmune or inflammatory diseases or disorders, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., reduces, deactivates, or inhibits OX40 activity.
US11136401B2	Car t-cell therapy directed to LHR for the treatment of solid tumors Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.
US11136395B2	PD-L1 -binding molecules comprising Shiga toxin A subunit scaffolds Provided herein are PD-L1 binding molecules comprising or conjugated to a toxin, e.g. a Shiga toxin A Subunit derived polypeptide. In some embodiments, the PD-L1 binding molecules are cytotoxic. In some embodiments, the PD-L1 binding molecules are capable of delivering a CD8+ T-cell epitope to an MHC class molecule inside a PD-L1 positive cell. The PD-L1 binding molecules described herein have uses for selectively killing specific cells (e.g., PD-L1 positive tumor cells and/or immune cells); for selectively delivering cargos to specific cells (e.g., PD-L1 positive tumor cells or immune cells), and as therapeutic and/or diagnostic molecules for treating and diagnosing a variety of conditions, including cancers and tumors involving PD-L1 expressing cells (e.g., PD-L1 positive tumor cells or immune cells).
US11136393B2	Methods for treating cancer in patients with elevated levels of Bim Materials and methods for treating cancer, including materials and methods for treating cancer in patients identified as having elevated levels of Bim.
US11136392B2	PD-1 immune modulating agents The present application provides anti-PD-1 antigen-binding proteins or a fragment thereof, as well as nucleic acids encoding anti-PD-1 antigen-binding proteins or CAR T cells expressing such antigen-binding protein or fragment. Also provided are methods of regulating T cells or treating patients using such constructs or cells.
US11136388B2	Biomarkers for anti-IL4-IL13 bispecific antibodies Disclosed herein are safe doses of dual-V-region antibody-like binding proteins or fragments thereof, as well as methods for assessing binding of dual-V-region antibody-like proteins or fragments thereof to their targets, and methods of treating idiopathic pulmonary fibrosis (IPF) by administering safe doses of dual-V-region antibody-like binding proteins or fragments thereof. In some embodiments, the dual-V-region antibody-like binding proteins or fragments thereof bind both IL-4 and IL-13.
US11136387B2	IL-13 antibody and preparation method and use thereof The present invention discloses IL-13 antibody, method of its preparation and use thereof. The IL-13 antibody comprises one or more of heavy chain CDR1, heavy chain CDR2 and heavy chain CDR3 of heavy chain variable region of the IL-13 antibody, and/or one or more of light chain CDR1, light chain CDR2, and light chain CDR3 of light chain variable region of the IL-13 antibody. The IL-13 antibody has a high affinity and can significantly inhibit the secretion of thymus activation-regulated chemokine and periostin as well as the expression of vascular cell adhesion molecule-1 induced by IL-13, it can significantly inhibit airway hyperresponsiveness in mice induced by IL-13, and therefore can be used in the preparation of drugs for preventing or treating IL-13 expression or dysfunction related diseases.
US11136386B2	Methods of treating Crohn's disease or ulcerative colitis by administering inhibitors of tumor necrosis factor-like cytokine 1A (TL1A) Provided are methods, systems, and kits for selecting a patient for treatment with a therapeutic agent based on a presence of a genotype associated with a positive therapeutic response to the therapeutic agent. The therapeutic agent, in some embodiments, is an inhibitor of TL1A activity or expression, such as for example, an anti-TL1A antibody.
US11136382B2	Antibodies and antibody fragments for binding to NAV1.9 polypeptides and methods for using same to treat pain-related disease The present invention provides an antibody or antibody fragment thereof for a targeted cytomembrane voltage-gated sodium channel α subunit Nav1.9. The specific binding target is a S3-4 ring of a voltage sensor paddle of a domain II of the voltage-gated sodium channel α subunit. The antibody or antibody fragment thereof is able to inactivate a voltage sensor valve, to make sodium ions unable to enter nerve cells normally, thereby achieving the effect of treating and relieving pains.
US11136381B2	Anti-C3 antibodies The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.
US11136379B2	Binding molecules directed against influenza hemagglutinin and uses thereof Multimeric binding molecules that are capable of specifically binding to hemagglutinin (HA) of at least two influenza A virus strains, said strains comprising HA of two different HA subtypes from phylogenetic group 2; or capable of specifically binding to hemagglutinin (HA) of at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2; or capable of specifically binding to hemagglutinin (HA) of at least one influenza B virus strain are provided. The binding molecules preferably are also capable of neutralizing at least two influenza A virus strains from phylogenetic group 2; or capable of neutralizing at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2; or capable of specifically neutralizing at least one influenza B virus strain.
US11136377B2	Antibodies and Fc fusion protein modifications with enhanced persistence or pharmacokinetic stability in vivo and methods of use thereof In certain embodiments, this present invention provides antibodies and Fc fusion proteins with enhanced pharmacokinetics, such as biotinylated antibodies or biotinylated Fc fusion polypeptides.
US11136375B2	Method for production of antibody The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.
US11136373B2	Fermentation process for increasing production level of recombinant human collagen The present invention provides a fermentation process for improving the production level of a recombinant human collagen. The process comprises inoculating a sterilized fermentation medium with a Pichia yeast solution, then performing fermentation culturing for 14-18 hrs, adding methanol to induce the expression, upon which sodium pyruvate is added to the fermentation medium, wherein the amount of the sodium pyruvate added is 0.01-10 g/L. In the fermentation process of the present invention, the sodium pyruvate is added in the methanol-induced expression stage, so that the biosynthesis rate of the recombinant human collagen is improved; and a continuous feed-batch mode is adopted, so that the biosynthesis rate of the recombinant human collagen is further improved, and the fermentation time is shortened. Meanwhile, the expression level of the recombinant human collagen is increased, the fermentation level is increased by more than 20%, and the production cost is reduced. The fermentation process is especially suitable for industrialized mass production of recombinant human collagen, and is of huge practical application value in industrial production.
US11136372B2	ApoC-II mimetic peptides The disclosure provides apolipoprotein C-II (apoC-II) mimetic peptides and methods for treating hypertriglyceridemia in a patient with an effective amount of an apoC-II mimetic peptide.
US11136371B2	Peptide compounds for suppressing inflammation Provided herein are peptides that exhibit ApoE biological activity, as well as compositions and pharmaceutical formulations that include the peptides. The peptides, compositions, and methods disclosed herein have broad applications as they can be used to treat a broad spectrum of injury, diseases, disorders, and clinical indications.
US11136370B2	Compositions and methods for thrombin generation assay In various embodiments, disclosed herein are assays for measuring thrombin generated (TG) in a blood sample, comprising: incubating the blood sample with TF, FIXa, and CaCl2; and measuring TG in the blood sample. Also disclosed herein are assays for determining a bleeding risk in a subject, comprising obtaining a blood sample from the subject; adding to the blood sample TF and/or FIXa; determining the amount of coagulation factor VIII (FVIII:C) in the blood sample; and determining (a) a mild bleeding risk in the subject if the amount of FVIII:C in the sample is >5 IU/dL, (b) a moderate bleeding risk in the subject if the amount of FVIII:C in the sample is 1-5 IU/dL, and (c) a severe bleeding risk in the subject if the amount of FVIII:C in the subject is <1 IU/dL.
US11136369B2	Expression of chimeric polypeptide with variable lymphocyte receptors on immune cells and uses for treating cancer This disclosure relates to recombinant cellular expression of chimeric proteins with peptide sequences derived from lymphocyte receptors and uses for treating cancer. In certain embodiments, the disclosure relates to a recombinant vector comprising a nucleic acid that encodes a chimeric protein with a segment with a targeting moiety based on a variable lymphocyte receptor (VLR) capable of binding a tumor associated antigen and a segment with a T cell signal transduction subunit. In certain embodiments, the recombinant vectors are used in immune based cancer treatments.
US11136364B2	Dual function proteins comprising FGF21 mutant protein and pharmaceutical composition comprising same The present invention provides a dual function protein prepared by linking a biologically active protein and an FGF mutant protein to an Fc region of an immunoglobulin, which has improved pharmacological efficacy, in vivo duration and protein stability. A dual function protein according to the present invention exhibits improved pharmacological efficacy, in vivo duration and protein stability, and a pharmaceutical composition containing the dual function protein as an active ingredient may be effectively used as a therapeutic agent for diabetes, obesity, dyslipidemia, metabolic syndrome, non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis or cardiovascular diseases.
US11136363B2	Compositions and methods for diagnosing and/or treating kidney injury One aspect of the technology relates to methods, assays and kits to identify ischemia and ischemic injury, including kidney injury, and are useful in determining efficacy of cancer treatments. In particular, differential phosphorylation of the nucleophosmin (NPM) polypeptide is an early marker of ischemic injuries such as kidney injury, AKI and ischemic renal cell injury. Another aspect of the technology relates to compositions and methods for the treatment of ischemia and kidney injury, including NPM inhibitory agents, including, but not limited to NPM inhibitory peptides for the treatment of ischemia and kidney injury.
US11136359B2	Mutated immunoglobulin-binding polypeptides The invention discloses a polypeptide with improved alkaline stability, which polypeptide comprises a mutant of a B or C domain of Staphylococcus Protein A (SpA), as specified by SEQ ID NO 1 or SEQ ID NO 2, or of Protein Z, as specified by SEQ ID NO 3, wherein at least the glutamine residue at position 9 has been mutated to an amino acid other than asparagine. The invention also discloses multimers of said polypeptide, as well as separation matrices comprising the multimers or polypeptides.
US11136357B2	Modified kappa light chain-binding polypeptides A kappa light chain-binding polypeptide comprising or consisting essentially of one or more mutated binding domains of Peptostreptococcus Protein L.
US11136352B2	Immunotherapy against several tumors including neuronal and brain tumors The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 30 peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
US11136351B2	Alpha conotoxin peptides The invention relates to alpha conotoxin (α-conotoxin) peptides and methods for their preparation. Also described are pharmaceutical compositions comprising alpha conotoxin (α-conotoxin) peptides and their use in the treatment or prevention of indications 5 associated with nicotinic acetylcholine receptors and/or voltage gated calcium channels.
US11136347B2	Crystalline forms of a fatty acid bile acid conjugate, preparation method thereof and use thereof The present disclosure relates to novel crystalline forms of compound (I) and processes for preparation and use thereof. Crystalline forms CS3, CS2, CS5 and CS8 of compound (I) of the present disclosure have advantages in at least one aspect of solubility, stability, melting point, hygroscopicity, particle size, bioavailability, processability, purification effect, flowability, adhesiveness, stability in drug product, in vitro and in vivo dissolution, etc., which provides new and better choices for preparation of drug product containing compound (I) and has significant values for future drug development.
US11136346B2	Asymmetric auxiliary group To provide a chiral reagent or a salt thereof.The chiral reagent has following chemical formula (I). In the formula (I), G1 and G2 are independently a hydrogen atom, a nitro group (—NO2), a halogen atom, a cyano group (—CN), a group of formula (II) or (III), or both G1 and G2 taken together to form a group of formula (IV).
US11136345B2	Large scale preparation of pseudo-trisaccharide aminoglycosides and of intermediates thereof Synthetic pathways for preparing pseudo-trisaccharide aminoglycoside compounds represented by Formula I or Ia as defined in the specification and donor and acceptor compounds useful for preparing such compounds are provided. A process of stereoselectively preparing compounds represented by Formula III as defined in the specification, while avoiding chromatographic separation of stereoisomers are also provided. Compounds prepared by the described processes and uses thereof are also provided.
US11136342B2	Carbonate prodrugs and methods of using the same The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
US11136341B2	Polycyclic aromatic compound and light emission layer-forming composition The objective of the invention is to provide a polycyclic aromatic compound in which solubility to a solvent, film formability, wet coatability, thermal stability, and in-plane orientation are improved. This objective is achieved by a light emission layer-forming composition comprising: as a first component, at least one type of dopant material selected from the group consisting of polycyclic aromatic compounds represented by general formula (A) and polycyclic aromatic oligomer compounds including a plurality of structures represented by general formula (A); as a second component, a specific low-molecular-weight host material; and, as a third component, at least one type of organic solvent. In formula (A), ring A, ring B, and ring C each independently represent an aryl ring or a hetero aryl ring, Y1 is B, and X1 and X2 each independently represent O or N—R wherein at least one of X1 and X2 is N—R.
US11136340B2	Amino-triazolopyridine compounds and their use in treating cancer The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where R1 and R2 have any of the meanings defined herein. The specification also relates to the use of such compounds and salts thereof to treat or prevent DNA-PK mediated disease, including cancer. The specification further relates to pharmaceutical compositions comprising such compounds and salts; kits comprising such compounds and salts; methods of manufacture of such compounds and salts; intermediates useful in the manufacture of such compounds and salts; and to methods of treating DNA-PK mediated disease, including cancer, using such compounds and salts.
US11136338B2	Fused thiazolopyrimidine derivatives as MNKs inhibitors The present invention relates to compounds of formulae I and H, or pharmaceutically acceptable salts or esters thereof. Further aspects of the invention relate to pharmaceutical compositions and therapeutic uses of said compounds in the treatment of diseases of uncontrolled cell growth, proliferation and/or survival, inappropriate cellular immune responses, inappropriate cellular inflammatory responses, or neurodegenerative disorders, preferably tauopathies, even more preferably. Alzheimer's disease.
US11136337B2	Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors The present invention relates to compounds of general formula I, wherein the groups R1 and R2 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.
US11136331B2	Methods of O-demethylation There is provided a novel process for the preparation of a compound of formula I, wherein R1, R2, W, Z and are as described in the description, by demethylation of a corresponding O-methyl derivative with a borohydride-based reagent. This process may be used in the preparation of buprenorphine.
US11136330B2	Synthesis of labeled imidazo[1,2-A]pyrimidines A method of synthesizing comprising a step of making an imidazo-pyrimidine compound by coupling a first compound of formula (II) with a second compound of formula (III) Followed by a deprotection and tosylation step. The methods are able to produce an isotopically substituted molecule having upwards of 95% purity relative to non-isotopically substituted molecules.The invention further comprises compounds of formula:
US11136322B2	Peripherally restricted GABA positive allosteric modulators for the treatment of irritable bowel syndrome and other ailments of the peripheral nervous system The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.
US11136320B2	Fused ring derivative used as FGFR4 inhibitor A compound represented by formula I or a pharmaceutically acceptable salt thereof and a use thereof in preparing a drug for treating, stopping or preventing a disease or disorder mediated by FGFR4 activity.
US11136319B2	Anti-influenza virus pyrimidine derivative The present invention discloses a class of anti-influenza virus compounds, and the use thereof in the preparation of a drug for treating diseases associated with influenza viruses. In particular, the present invention discloses a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.
US11136313B2	Compounds, compositions, and methods for modulating CFTR The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.
US11136311B2	Heteroaromatic derivatives as NIK inhibitors The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-κB-inducing kinase (NIK—also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.
US11136308B2	Substituted quinazoline and quinazolinone compounds and methods of use thereof Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I): (Formula (I)) or a pharmaceutically acceptable salt, stereoisomer thereof, wherein G, Y, R, R1, R2a, R2b, R2c, L, L1 and E are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of G12C mutant KRAS protein for treatment of disorders, such as cancer, are also provided. Preferred compounds are quinazoline and quinazolinone derivatives and in particular 1-(6-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)azetidin-1-yl)prop-2-en-1-one derivatives and similar compounds.
US11136307B1	Crystalline form of tegavivint, method of preparation, and use thereof The present invention relates to crystalline forms of (9E,10E)-2,7-bis((3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime, pharmaceutical compositions comprising the crystalline form, processes for preparing the crystalline form and methods of use therefore.
US11136306B2	Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-peridine-2,6-dione Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed.
US11136305B2	Nicotine salts, co-crystals, and salt co-crystal complexes The invention provides certain nicotine salts, co-crystals, and salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, nicotine salts with mucic acid, 3,5-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid, and crystalline polymorphic forms of nicotine 4-acetamidobenzoate, nicotine gentisate, and nicotine 1-hydroxy-2-naphthoate are described. The invention further provides methods of preparation and characterization of such nicotine salts, co-crystals, and salt co-crystals and polymorphic forms thereof. In addition, tobacco products, including smoking articles, smokeless tobacco products, and electronic smoking articles comprising nicotine salts, co-crystals, and/or salt co-crystals are also provided.
US11136302B2	Single step process for the synthesis of furan derivatives from carbohydrates The present invention discloses a single step process for the synthesis of furan derivative from carbohydrate comprises stirring the reaction mixture of carbohydrate in solvent in presence of catalyst at temperature in the range of 170 to 190° C. for the period in the range of 23 to 25 hrs to afford corresponding furan derivative.
US11136296B2	Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof The present application relates to novel substituted N-arylethyl-2-arylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and inflammatory disorders.
US11136295B2	D-amphetamine compounds, compositions, and processes for making and using the same Disclosed are d-amphetamine compounds and compositions comprising at least one organic acid covalently bound to d-amphetamine, a salt thereof, a derivative thereof, or a combination thereof. Methods of making and using the same are also disclosed.
US11136291B2	Antifungal compounds and uses thereof Provided herein are compounds (e.g., compounds of Formulae (I), (II), and (III)) which are anti-fungal agents and can be used in the treatment of diseases, including infectious diseases. The invention provides methods of treating diseases in a subject (e.g., infectious diseases such as fungal infections), and methods of killing or inhibiting the growth of fungi in or on a subject or biological sample. The compounds may be used in subjects, in clinical settings, or in agricultural settings.
US11136286B2	Diamine compound, and polyimide compound and molded product using the same [Problems to be solved] The present invention provides a novel diamine compound which allows for the synthesis of a polyimide compound having a high solubility in an organic solvent and a high melt moldability.[Solution] The diamine compound according to the present invention is characterized by being represented by the following general formula (1): (wherein R1 to R8 are each independently selected from the group consisting of a hydrogen atom, a fluorine atom, a substituted or unsubstituted alkyl group, and a substituted or unsubstituted aromatic group; and at least one of R1 to R8 is a substituted or unsubstituted aromatic group).
US11136283B2	Recovering and purifying resveratrol produced by microbial fermentation The present invention relates to a process for recovering and purifying resveratrol produced by microbial fermentation. More particularly, the present invention relates to a process for recovering and purifying resveratrol produced by yeast fermentation.
US11136282B2	Method for producing 2,3,3,3-tetrafluoropropene and facility for implementing said method The present invention relates to a process for producing 2,3,3,3-tetrafluoropropene, comprising the steps: i) providing a stream A comprising at least one starting compound selected from the group consisting of 2-chloro-3,3,3-trifluoropropene and 2,3-dichloro-1,1,1-trifluoropropane; and ii) in an adiabatic reactor comprising a fixed bed composed of an inlet and an outlet, bringing said stream A into contact, in the presence or absence of a catalyst, with HF in order to produce a stream B comprising 2,3,3,3-tetrafluoropropene, characterized in that the temperature at the inlet of the fixed bed of said adiabatic reactor is between 300° C. and 400° C. and the longitudinal temperature difference between the inlet of the fixed bed and the outlet of the fixed bed of said reactor is less than 20° C.
US11136279B2	Integrated process for producing olefins from alkanes by hydrogen transfer This application relates to transfer hydrogenation between light alkanes and olefins, and, more particularly, embodiments related to an integrated olefin production system and process which can produce higher carbon number olefins from corresponding alkanes. Examples methods may include reacting at least a portion of the ethylene and the at least one alkane via transfer hydrogenation to produce at least a mixed product stream comprising generated ethane from at least a portion of the ethylene, unreacted ethylene, and an olefin corresponding to the at least one alkane.
US11136273B2	Liquid products having increased solids concentrations The present invention discloses liquid compositions that include an active compound, water, and means for inhibiting crystal formation or precipitation of the active compound in the liquid composition.
US11136272B2	Method of producing fired ceramic article and method of firing ceramic green body The present disclosure is related to a method of producing a fired ceramic article. The method may include: heating a ceramic green body in a kiln, and controlling oxygen concentration in the kiln such that the oxygen concentration swings during the heating of the ceramic green body.
US11136271B2	Aluminum nitride particles Aluminum nitride particles used as a material of an aluminum nitride sintered compact are disclosed. The aluminum nitride particles may have a same crystal orientation. The aluminum nitride particles each have an aspect ratio of 3 or more, a plate-like shape, a planar length of 0.6 μm or more and 20 μm or less, and a thickness length of 0.05 μm or more and 2 μm or less.
US11136267B2	Gypsum panels, methods, and systems Gypsum panels and methods of making gypsum panels are provided. A method of making a gypsum panel includes combining gypsum stucco and a halide salt sequestration agent with water to form a gypsum slurry and setting the gypsum slurry to form at least a portion of a gypsum core, wherein the halide salt sequestration agent is present in an amount effective to sequester at least a portion of halide salt present in the gypsum stucco. A gypsum panel includes a gypsum core that comprises set gypsum and a halide salt sequestration agent, wherein the halide sequestration agent sequesters at least a portion of halide salt present in the gypsum core.
US11136263B2	Functional glazing provided with a permanent protective film A glazing article, includes a substrate made of glass or made of organic substance, on the surface of which are deposited a layer or a stack of layers conferring, on the article, a functionality, in particular solar protection, thermal insulation or anticondensation properties, with a total thickness of between 5 nanometers and 400 nanometers, an organic film covering the layer or the stack of layers, the thickness of the polymer film being between 300 nanometers and 10 micrometers, wherein a texturing element is present under the layer or the stack of layers, the roughness of the surface of the texturing element being such that: the arithmetic mean deviation Ra is between 50 nm and 2 micrometers, limits included, the base length RSm is between 5 micrometers and 300 micrometers, limits included.
US11136262B2	Fitout articles and articles of equipment for kitchens or laboratories with a display device A fitout article or article of equipment for a kitchen or laboratory is provided. The article has a display device, a separating element, and a covering. The covering is on an interior side of the separating element and has a cutout at the separating element. The separating element has a light transmittance of at least 5% and at most 70%. The covering has light transmittance of at most 7% and a colour locus in the CIELAB colour space with coordinates L* of 20 to 40, a* of −6 to 6 and b* of −6 to 6, and the colour locus of D65 standard illuminant light, after passing through the substrate, is within a white region W1 determined in the chromaticity diagram CIExyY-2° by the coordinates: White region W1 xY 0.270.21 0.220.25 0.320.37 0.450.45 0.470.34 0.360.29.
US11136260B2	Radiopaque glass and use thereof The invention relates to a radiopaque glass having a refractive index nd of 1.480 to 1.561, this glass, apart from impurities at most, being free from SrO and PbO. The glass is based on the SiO2, Al2O3 and B2O3 system. The radiopacity can be adjusted using Cs2O in particular in combination with BaO and/or SnO2 optionally in conjunction with fluorine. The glass may be used in particular as dental glass or as optical glass.
US11136259B2	Photosensitive glass paste, electronic component, and method for producing electronic component A photosensitive glass paste contains a photosensitive organic component, and an inorganic component containing a glass powder and a ceramic filler. The glass powder contains a glass powder having a crystallization point. The difference between the crystallization point and the softening point of the glass powder having a crystallization point is from 85° C. to 180° C. The glass powder having a crystallization point is preferably a SiO2—B2O3—BaO—ZnO—Al2O3—MgO—La2O3 glass powder.
US11136255B2	Systems and methods for thermally controlling warp Embodiments disclosed herein include systems and methods for controlling material warp that include placing the shaped mold in a heating device, forming a glass material into a shaped mold, and cooling the glass material and the shaped mold to a predetermined viscosity of the glass material. Some embodiments include, a predetermined time prior to removing the glass material and the shaped mold from the heating device, holding the glass at the mold in the heating device where the heating device temperature is substantially equal to mold and glass temperature just prior to exiting to ambient temperature. Some embodiments include removing the glass material and the shaped mold from the heating device to further cool the glass material and the shaped mold at ambient temperature, where after removing the glass material and the shaped mold from the heating device, the glass material will exhibit controlled or desired material warp.
US11136250B2	Reactor for integral water treatment The invention relates to a simplified modular reactor, where the method of purifying swimming pool waters can be carried out in an integral manner, where said method may comprise simultaneously applying the techniques of: oxidation-disinfection, ultraviolet radiation, and pH adjustment on the water to be treated.
US11136249B1	Destabilization and separation of high stable colloids Provided herein are compositions and methods useful for the treatment of wastewater comprising colloidal impurities. In certain aspects and embodiments, the compositions and methods include a natural deep eutectic solvent (NADES) coagulant including a hydrogen bond acceptor and a hydrogen bond donor, wherein the NADES is a liquid at room temperature.
US11136246B2	Recycling automotive phosphate rinse water stream The present disclosure relates to recycling automotive phosphate rinse water. An apparatus and method is disclosed for treating process water containing phosphate. The apparatus may include a process water line. The process water line may be in fluid communication with a sample process water line. The sample process water line may be in fluid communication with a dilution line. The sample process water line, the dilution line, and a phosphate analyzer may be in fluid communication with a diluted process water line. The apparatus may also include a chemical additive feed line in fluid communication with the process water line downstream from the sample process water line.
US11136245B2	Salt wall in a molten salt reactor Some embodiments include a method comprising: flowing a molten salt out of a molten salt reactor at a first temperature, heating the molten salt reactor to a second temperature above the melding point of the second salt mixture causing the second salt mixture to melt; flowing the second salt mixture out of the molten salt reactor; flowing a third salt mixture into the molten salt reactor; and cooling the molten salt reactor from the second temperature to a third temperature causing the third salt mixture to solidify on the interior surface of the housing. In some embodiments, the molten salt may include a first salt mixture comprising at least uranium. In some embodiments, the first temperature is a temperature above the melting point of the first salt mixture.
US11136238B2	OTM syngas panel with gas heated reformer The present invention generally relates to an oxygen transport membrane syngas panel whereby the reformer layer of the panel is eliminated, and the primary reforming function is integrated into the manifold as a gas heated reformer with product syngas as the source of heat.
US11136237B2	Device for suppressing stray radiation A device for suppressing stray radiation includes a Micro-ElectroMechanical System (MEMS) sensor module and a conductive cage structure. The conductive cage structure may enclose the MEMS sensor module in order to suppress penetration of stray electromagnetic radiation with a stray wavelength λo into the conductive cage structure, and the conductive cage structure may be arranged to be thermally insulated from the MEMS sensor module. The device may also include a connecting line. The connecting line may be connected to the MEMS sensor module and fed through the conductive cage structure by a capacitive element.
US11136232B2	Water discharge device and method for controlling the same A water discharge device includes a case, a microphone, a voice recognition module, a speaker, a first elevation cover connected to the case, a second elevation cover configured to move upward and insert into an inside of the first elevation cover, an elevation motor connected to the second elevation cover, a water discharge nozzle disposed at a lower end of the second elevation cover, a water discharge valve configured to regulate water flow toward the water discharge nozzle, a flow sensor configured to sense a flow rate of the water flow, a sensor disposed at the second elevation cover and configured to, based on the second elevation cover moving downward, sense whether the sensor contacts a container disposed below the second elevation cover, and a controller configured to control operation of the elevation motor and the water discharge valve.
US11136230B2	Apparatus for opening safety locked bottle caps An apparatus for opening safety locked bottle caps is disclosed herein. The apparatus enables users to open safety locked bottle caps in a safe and effective manner. In one embodiment of the invention, the various elements of the inventive apparatus enable a user to remove a bottle cap when sufficient downward force is applied to the handle of the apparatus. In one embodiment, the apparatus is comprised of an engagement mechanism that lodges into the bottom portion of the bottle cap's outer lip. The engagement mechanism is designed to remain lodged within the bottle cap's outer lip through a substantial portion of the opening motion. This feature prevents the inventive apparatus from “slipping-off” from the bottle cap while a user is trying to remove the bottle cap from the bottle.
US11136226B2	Apparatus comprising a pivotable arm and a configurable spring Method and device (1) for lifting loads (7). An arm (2) that is the load or that supports a load (7) is pivotably connected to a reference. The load results in a torque. At least a part of the counter-torque to result in a system supporting the load is provided by a gas or hydro-pneumatic spring (60).
US11136223B2	Vacuum extraction for material sorting applications Systems and methods for vacuum extraction for material sorting applications are provided. In one embodiments, a vacuum object sorting system comprises: a vacuum extraction assembly that includes at least one vacuum extractor device having an inlet and an outlet, wherein the at least one vacuum extractor device is configured to convert a controlled compressed air stream into a channeled vacuum airflow entering the inlet and exiting the outlet; and an object recognition device coupled to sorting control logic and electronics, wherein the controlled compressed air stream is controlled in response to a signal generated by the object recognition device; wherein the at least one vacuum extractor device is configured to capture a target object identified by the sorting control logic and electronics utilizing the channeled vacuum airflow, and further utilizing the channeled vacuum airflow, to pass the target object through the inlet and outlet to a deposit location.
US11136221B2	Radial flux permanent magnet elevator motor A radial flux permanent magnet elevator motor includes a motor frame forming the stator frame having fixing points to be fixed to an elevator guide rail, which frame has a back wall facing and/or abutting with the guide rail, which motor frame includes an axially extending flange protruding away from the back wall in the direction of the rotor, and which motor frame includes at least one axially extending first wall section in a defined radial distance from the axis of the motor frame, which first wall section is configured to support a stator winding of the motor. The rotor includes a central hub protruding into the flange of the motor frame and is rotatively supported within the flange via bearings, which rotor includes a traction sheave in a first radial distance from the motor axis and a ring-like support wall in a second radial distance from the motor axis for supporting permanent magnets, which second distance is larger than the first distance, and whereby the stator winding and the permanent magnets form a radial air gap.
US11136219B2	Connecting device and method for connecting a wall element in an elevator car An elevator car has a connecting device and at least one wall element, wherein the connecting device connects the at least one wall element with a bare ceiling of the elevator car. The connecting device includes a rail element with two legs, of which a first leg bears in the mounted state against the bare ceiling and a second leg has a mounting surface for the at least one wall element. The mounting surface has a first hole for suspending the at least one wall element. The at least one wall element has a suspension element at an edge which faces upwardly in the mounted state for engaging into the first hole of the connecting device.
US11136218B2	Method for fastening a rail of an elevator system in an elevator shaft A method for fastening a rail of an elevator system to a bearing element fixed in an elevator shaft utilizes a clamp set having a clamp and a spacer. The clamp is arranged on a side part of a rail foot arranged on the bearing element whereby the clamp connects to the bearing element in a fastening zone of the clamp and a contact zone of the clamp is situated on a bearing side on an upper face of the side part. The spacer defines a mounting distance between the contact zone and the bearing side such that the clamp is partly elastically and plastically deformed in the fastening zone when connected. The spacer is then at least partially removed so that a distance between the contact zone and the bearing side is reduced.
US11136210B2	Friction transport device and paper sheet transport device To correct a posture of a paper sheet inserted from various positions and angles to a normal transport state without causing any deformation due to contact with a side wall while transporting the paper sheet continuously and non-intermittently. A drive-side unit (20) includes at least one drive roller (25) that is supported rotatably about a shaft orthogonal to a normal paper-sheet transport direction and axially movably, an elastic biasing member (40) that elastically biases the drive roller in an axial direction, and a cam mechanism (50) that transmits a driving force from a driving source to the drive roller, and operates when an external force exceeding a predetermined value in a direction other than a normal transport direction is applied to the paper sheet transported by the drive roller, so as to change an axial position of the drive roller against an elastic biasing force, and a driven-side unit (100) includes a driven roller that changes a transport grip between the drive roller and a paper sheet according to a change of an axial position of the drive roller.
US11136190B2	Automated laboratory system and related systems, methods, and devices An automated laboratory system includes a vertical shelving system including a frame and at least one shelf movably mounted to the frame such that the at least one shelf is movable relative to the frame between a docked position and an undocked position, the at least one shelf being configured to carry at least one instrument. The system also includes a robotic device proximate the vertical shelving system and being configured to access the at least one instrument carried by the at least one shelf.
US11136187B1	Control system for a refuse vehicle A refuse vehicle includes a chassis, a battery, a vehicle body, an electric power take-off system, a lifting system, and a disconnect. The chassis supports a plurality of wheels. The battery is supported by the chassis and is configured to provide electrical power to a first motor. Rotation of the first motor selectively drives at least one of the plurality of wheels. The vehicle body is supported by the chassis and defines a receptacle for storing refuse. The electric power take-off system is coupled to the vehicle body and includes a second motor configured to convert electrical power received from the battery into hydraulic power. The lifting system is coupled to the vehicle body and is movable relative to the receptacle using hydraulic power from the electric power take-off system. The disconnect is positioned between the battery and the electric power take-off and is configured to selectively decouple the electric power take-off system from the battery.
US11136186B2	Trash can assembly Various embodiments of a trash can assembly (e.g., a receptacle configured to receive refuse, recycleable materials, or otherwise), and related methods, are provided. Some embodiments of the trash can assembly include a body component and a lid configured to move between an open position and a closed position. In some variants, the lid can be moved between the open and closed positions by a power operated driving mechanism, such as a motor and/or other drivetrain components. In certain embodiments, the trash can assembly includes a clutch mechanism to facilitate manual operation of the lid while inhibiting or preventing damage to the motor and/or other drivetrain components.
US11136183B2	Container A container includes: an upper container part constituting an upper half of a container body having a horizontally elongate rectangular parallelepiped shape; a lower container part constituting a lower half of the container body; four posts disposed at the four corners of the container body; and hinges 20 rotatably retaining the posts at the four corners of at least one of the upper container part or the lower container part. The container body can be transformed between a first state in which the upper container part is retained at a first height with respect to the lower container part and a second state in which the container body is retained at a second height that is lower than the first height. In the second state, the posts are rotated inward in the lengthwise direction of the container body by the hinges.
US11136176B2	Contact lens blister package with lens cradle A blister package for a contact lens is provided. The blister package includes a body defining a handle and a well, a flexible top contacting the body and closing the well, and a lens cradle that includes a lens support bowl. The lens cradle is attached to the inner surface of the flexible top. By peeling away the flexible top, the lens cradle is lifted away from the bottom surface of the well and the lens is raised out of the well, cradled by the lens support bowl, and presented for easy fingertip manipulation by a user.
US11136175B2	Pack made of polyester with a thermoformable lower film and a sealable and peelable upper film, use thereof, and process for its production The invention relates to transparent packaging for vacuum forming, inter alia, formed from a biaxially oriented, thermoformable polyester film as lower film (A) and a biaxially oriented polyester film as upper film (B) that is both heat-sealable and peelable (at least when the material is hot) in relation to the lower film (A). The present invention further relates to the use of such packaging to produce sealed, thermoformed packs, and to the processes for their respective production.
US11136174B2	Container lid assembly A container lid assembly includes a movable lid, a ratchet ring, a rotary symbol ring, an inner cover, and an annular housing. Once coupled to a container, the container lid assembly can automatically and accurately record the number of times for which it has been opened, thereby reminding the user of whether the contents of the container (e.g., medicine) have been used, lest the user miss a dose of the medicine or retake the medicine unnecessarily. The container lid assembly also allows a plurality of containers to be connected in series to facilitate carrying and management.
US11136173B2	Child-resistant storage container The technology disclosed herein includes methods and apparatus of a childproof storage container, which includes a lid and a base portion with seesaw-style latches. The seesaw-style latches are configured to unlock a childproof storage container in a locked position upon simultaneously release. Each seesaw-style latch may include a flared end. In a locked position, the childproof storage container may be unlocked and opened upon depression of the flared end of the seesaw-style latch, which rotates the seesaw-style latch from the lid. Each seesaw-style latch may include a standing rib to prevent over-rotation of each seesaw-style latch and/or a chamfer to facilitate closure. The base portion may include a base portion flange, which includes a plurality of female recesses to receive the plurality of male teeth of a lid flange. The base portion and the lid may include opposing walls that interlock during a closed position and/or a gasket for sealing.
US11136171B1	Lid A lid is disclosed having a spring mechanism that pushes up an activator lever while also lifting up a flow stopper that keeps fluid from the mug and out through the lid. Due to the design of the lid, a mug can be filled without having to remove the lid. Similarly, the user does not have to touch any part of the lid from which water flows. This makes the use of this lid more sanitary.
US11136166B2	Pouch with flexible self-sealing dispensing valve The present invention is directed to fluid-dispensing flexible pouches having at least a first wall portion, a second wall portion and a means to manually discharge a fluid product from inside the pouch. The means to manually discharge a fluid from inside the pouch comprises an orifice formed in either one of the first or second wall portions or a patch, and a flexible self-sealing dispensing valve having at least two intersecting lines of weakness formed in either one of the first or second wall portions or the patch.
US11136165B1	Modular shipping base A re-usable, returnable, stackable, modular shipping base incorporates replaceable components to make the base relatively quick and cost effective to repair. The shipping base is formed from a number of stamped or cut sheet materials (e.g., sheet metal) that are then folded and attached to one another using a tab system. When a component is damaged, the damaged component may be removed from the base and replaced with another mass produced, stamped sheet material component. Components are attached to one another via adhesive, stitch welding, skip welding, spot welding, or any other applicable process. Some components (e.g., a center support) may also be assembled using a tab (from the center support) and slot (in a deck pan) system.
US11136156B1	Retaining collapsible totes Aspects described herein include an apparatus for retaining a collapsible tote. The apparatus includes a wall member and one or more engagement members projecting from one or more surfaces of the wall member. The one or more engagement members are arranged and dimensioned to removably engage respective portions of the collapsible tote, suspending the collapsible tote beside a first surface of the one or more surfaces. The wall member is inclined such that, when the collapsible tote is suspended beside the first surface, the collapsible tote is gravitationally urged toward an uncollapsed configuration.
US11136154B2	Packaging machine for bedding products A packaging machine for packaging a product. The machine has a frame for supporting the product and a source of packaging material for supplying packaging material into a position to be engaged by and at least partially surround the product. At least one upper sealing assembly is adapted to move between an actuated position and a non-actuated position. The upper sealing assembly comprises at least one sealing element for forming a seal along adjacent edges of the packaging material. At least one lower sealing assembly is adapted for cooperating engagement with the upper sealing assembly in its actuated position. The at least one upper and lower sealing assemblies are positioned for clamping engagement of the packaging material therebetween for forming the seal when the upper sealing assembly is moved to its actuated position in engagement with the lower sealing assembly.
US11136153B2	Method and system for order fulfilment A method of fulfilling an order comprising at least one product is provided. The method includes receiving an order comprising at least one product, determining a suitable case from a plurality of available cases for holding the at least one product, said determining being a function of one or more characteristics of each product of the at least one product and one or more characteristics of the plurality of available cases; forwarding information identifying the suitable case to a case former; providing a case blank corresponding to said suitable case to said case former; erecting a suitable case from said case blank corresponding to said suitable case with said case former; and prior to the loading said suitable case with said at least one product, labelling said suitable case with at least one label.
US11136151B1	Orbital wrapping machine An orbital wrapping machine includes a rotatable wrapping wheel and a drive system, with one or more roll mounts arranged circumferentially around the wrapping wheel and each configured to rotatably support a roll of stretch film. Rotation of the wrapping wheel about an object causes the stretch film to be wrapped around the object. A tensioning system applies a frictional resistance to rotation of each roll of stretch film as the firm is drawn off each roll during rotation of the wrapping wheel. The tensioning system includes a friction material and an adjuster that is capable of urging the friction material against an outer surface of the roll of stretch film at different levels of pressure to adjust the frictional resistance of each roll of stretch film.
US11136150B1	Apparatus for installing a bung plug in and/or extracting a bung plug from a container Apparatus for installing a bung plug in and/or extracting a bung plug from a container positioned below the apparatus includes a carrier selectively movable up and down relative to the container, a bung plug engagement tool carried by the carrier and including a bung plug wrench and a centering collar carried by the carrier and at least partially surrounding the bung plug wrench.
US11136140B2	Methods and apparatus to project aircraft zone indicators Methods and apparatus to project aircraft zone indications are disclosed. A disclosed example projection system for displaying an indicator pertaining to an aircraft includes a condition analyzer to determine a condition of at least one of the aircraft or a zone surrounding the aircraft, and a projector to project the indicator on or proximate the zone based on the determined condition.
US11136138B2	Aircraft control method and apparatus and aircraft This invention discloses an aircraft control method, apparatus and an aircraft. The invention relates to the field of aircraft control technologies. The method includes: obtaining ambient luminance data by a luminance sensing apparatus of an aircraft; determining whether the ambient luminance data satisfies a luminance value required for normal running of a vision system of the aircraft; and adjusting, when the ambient luminance data does not satisfy the luminance value required for normal running of the vision system of the aircraft, a working status of a light emitting apparatus on the aircraft to change light emitting luminance of the light emitting apparatus. The foregoing aircraft control method, apparatus and the aircraft can accurately learn a flight environment in which the aircraft is located, thereby effectively implementing vision positioning on the aircraft and more conveniently controlling the aircraft.
US11136137B2	Non-intrusive passenger rest cabin monitoring system A passenger cabin monitoring system includes infrared cameras disposed in respective passenger rest compartments, a flight attendant information system including at least one display and at least one speaker, and a computing device in communication with the infrared cameras and the flight attendant information system. The computing device is configured to detect a temperature of a portion of passenger rest compartment based on one or more thermal images generated by a respective infrared camera of the passenger rest compartment. The computing device is further configured to compare the temperature of the portion of the passenger rest compartment with a predetermined critical temperature and provide an audible alert and/or a visual alert via the flight attendant information system to indicate a critical status of the passenger rest compartment when the temperature of the portion of the passenger rest compartment is above the predetermined critical temperature.
US11136136B2	System and method for flight mode annunciation In an embodiment, a method of indicating flight modes of a rotorcraft includes: detecting a change in flight mode of the rotorcraft from a previous flight mode to an active flight mode, the active flight mode and the previous flight mode each being from one of a first subset or a second subset of a plurality of flight modes; determining whether the active flight mode and the previous flight mode are from different subsets of the plurality of flight modes; and updating one or more flight mode indicators on an instrument panel of the rotorcraft in response to the active flight mode and the previous flight mode being from different subsets of the plurality of flight modes.
US11136133B2	Passenger door arrangement for an aircraft segment A passenger door arrangement for an aircraft segment, which arrangement comprises a passenger door, which is configured to assume a raised state and a lowered state, and a “girt bar,” for arming and disarming an escape slide, the girt bar not altering its position relative to the passenger door in the transition from disarming to arming, when the passenger door is in the lowered state. Additionally an aircraft segment, which comprises the passenger door portion and a fuselage portion, an external engagement arrangement being fixed to the fuselage portion.
US11136130B2	Aircraft enviromental control system with series bleed air turbines An environmental control system of an aircraft includes a ram air circuit including a ram air shell having at least one heat exchanger positioned therein, at least one dehumidification system arranged in fluid communication with the ram air circuit, a compressing device arranged in fluid communication with the ram air circuit and the dehumidification system, and an expansion device separate from the compressing device and arranged in fluid communication with the ram air circuit and the at least one dehumidification system. The environmental control system receives a flow of a first medium and a flow of a second medium. The environmental control system is operable in a plurality of modes and in a first mode, a flow of the first medium is provided to the compressing device and the expansion device in series.
US11136129B2	Seat track fittings and methods for installing passenger seats in aircraft cabins using seat track fittings Provided are seat track fittings and methods for installing passenger seats in aircraft cabins using these seat track fittings such that the same seat can be installed on different types of seat tracks. A seat track fitting comprises a leg support, a pin, and a base interconnecting the leg support and pin. During installation of the seat track fitting, the pin is inserted into an attachment opening of the seat track. The attachment opening is selected based on the desired position of a seat. A removable fastener then protrudes through the base of the seat track fitting and is inserted into another attachment opening of the seat track. The seat is then attached to the seat track fitting by inserting the stud end of the seat into the leg support of the seat track fitting and fixing the stud end within the leg support.
US11136126B2	Platform first class Described are examples of a seating arrangement for an aircraft with a first seat in a first accommodation space and a second seat in a second accommodation space, wherein the first and second accommodation spaces are configured to share a common floor space at a floor level of the aircraft. One seating arrangement includes a divider screen located between the first and second accommodation spaces, moveable, by sliding in a direction along the common floor space, between a stowed position permitting passenger egress between the first and second accommodation spaces across the common floor space, and a deployed position preventing passenger egress between the first and second accommodation spaces across the common floor space.
US11136122B2	Arrangement and method with a flyable unmanned transporting device The disclosure relates to an arrangement comprising a flyable unmanned transporting device and a movable catch arm, which is provided at a ground station, for holding the transporting device at the ground station, wherein at least one recess is provided on the transporting device, and the catch arm, at its end facing away from the ground station, has at least one expansion element which can be introduced into the at least one recess and, in the introduced state, can be expanded in order to produce a form fit between the at least one recess and the at least one expansion element.
US11136115B2	Tilted propellers for enhanced distributed propulsion control authority An aircraft comprises a fuselage, one or more support structures connected to the fuselage, one or more engines or motors disposed within or attached to the one or more support structures or the fuselage, and a distributed propulsion system. The distributed propulsion system comprising two or more propellers symmetrically distributed in an array along the one or more support structures with respect to a center of gravity of the aircraft and operably connected to the one or more engines or motors, wherein each propeller has a rotation direction within a tilted plane of rotation, and a summation of horizontal force vectors created by the tilted plane of rotation of all the propellers is substantially zero when all the propellers are creating a substantially equal thrust magnitude. Movement of the aircraft is controlled by selectively increasing or decreasing a thrust of at least one of the two or more propellers.
US11136114B2	Control system and method for landing gear extension/retraction A control system has first and second processing modules for controlling retraction and extension of an aircraft landing gear assembly. The processing modules operate independently providing redundancy. Each processing module is configured to perform a first sequence of steps for retracting the landing gear assembly and a second sequence of steps for extending the landing gear assembly. A step of switching control from one processing module to the other (e.g. an avionics side changeover step) is performed (a) as part of the first sequence of steps, but only after the landing gear assembly has been retracted, or (b) as part of the second sequence of steps. By ensuring that the step of switching control is performed at such times, and not for example between initiation of the first sequence of steps and the retraction of the landing gear assembly, the landing gear assembly may be retracted sooner after such initiation.
US11136113B2	Single axle, semi-levered landing gear with shortening mechanism A landing gear including a shock strut assembly including an outer cylinder coupled to an airframe, a wheel movably coupled to the outer cylinder so as to reciprocate substantially along a longitudinal axis of the outer cylinder, and a shrink mechanism including a pivot arm pivotally coupled to the shock strut assembly, a drive member coupling the pivot arm to a landing gear retract mechanism, a driven member coupled to the pivot arm, a first shrink link member coupled to the pivot arm by the driven member, and a second shrink link member coupled to the first shrink link member and to the shock strut assembly. Rotation of the pivot arm by the drive member, effects a folding movement between the first shrink link member and the second shrink link member, and the folding movement effects at least a retraction of the wheel relative to the outer cylinder.
US11136109B2	Airfoil for a rotary machine including a propellor assembly In some embodiments, an airfoil comprises a proximal end; a distal end opposite said proximal end; a distal portion extending adjacent said distal end; an edge extending between said proximal end and said distal end; and a surface extending between said proximal end and said distal end, said edge and said surface defining a sweep and a cahedral through said distal portion, wherein the distal portion extends over an acoustically active portion of the airfoil.
US11136108B2	Composite structural element A composite structural element comprising a substantially planar main section defining a coordinate system with a first axis extending along a longitudinal axis of the structural element and a second axis extending perpendicular to the longitudinal axis within the planar main section. The structural element contains a basic lay-up of single plies, each comprising a fiber-reinforced composite material with a substantially unidirectional fiber orientation. The lay-up comprises N plies arranged from top to bottom in the following form: [[α, β]M; [γ]K; [β, α]M], wherein α, β and γ represent one ply having an angle enclosed between the first axis and the unidirectional fiber orientation of the one ply, respectively, [x]y means y plies each having angle x; [x, y]z means z pairs of plies, K and M are both positive integers equal to or greater than 1: N=4·M+K.
US11136096B2	Unmanned aerial vehicle search and rescue system A search and rescue drone system includes a buoyant body member, a frame attached to the buoyant body member for carrying a motor and propeller, and an electronic array including a camera, GPS, an EPIRB radio distress beacon, and a transmitter/receiver for remote control flying the drone and communicating with an operator. A laser guidance system may provide coordinates for landing near a swimmer in distress. The search and rescue drone may also be programmed to simply fly to the location of an electronic wearable device, like a bracelet, that is worn by a man overboard. In another embodiment, the search and rescue drone includes pivoting motor mounts, so that it can take off and land vertically with propellers rotating in a horizontal plane, and then the propellers may pivot to rotate in a vertical plane for propulsion across water similar to a fan boat with rescued people aboard.
US11136094B2	Construction method for column platform barrel deck and topsides, and column platform A construction method for a column platform barrel deck and topside facilities, and a column platform. The construction method includes: prefabricating topside facilities in form of modules one by one, lifting each module to a predetermined position on the topmost deck of the upright barrel, and then connecting the modules to each other and forming a module-integration bottom deck at the bottom; during construction of the upright barrel, a skylight opening is reserved on the barrel topmost deck for the installation of the topsides, and the skylight opening allows the modular-integration bottom deck to be placed inside; an on-site closing gap is formed between the edge of the skylight opening and the outer edge of the modular-integration bottom deck perimeter; using the on-site closing gap connection structures to fill the on-site closing gap, so that the modular-integration bottom deck and the barrel topmost deck jointly form an integrated platform deck.
US11136090B2	Disc brake rotor adapter, disc brake rotor including adapter, magnetism generation device A magnetism generation device is attachable to a disc brake rotor adapter for a bicycle hub. The magnetism generation device comprises a magnetism generation portion and a holder. The holder has a first portion and a second portion. The first portion supports the magnetism generation portion. The second portion is releasably attached to the first portion with a portion of the disc brake rotor adapter disposed between the first and second portions while the magnetism generation device in an installed state on the disc brake rotor adapter.
US11136089B2	Transforming electric scooter having a stand-on configuration and a ride-on configuration An electric transformable scooter that can transform between a stand-on configuration and a ride-on configuration. The scooter has a fixed frame member at the front to which the front wheel and handlebar are mounted, and movable frame member that extends between the rear wheel and the fixed frame member. The front end of the movable frame member slides or otherwise adjusts to either a lower position or an upper position on the fixed frame member. When the movable frame member is at the lower position and locked thereat, it is generally horizontal, and its top surface defines a stand-on floorboard for stand-on operation. When the movable frame member is slid to its upper position and locked thereat, it is inclined from front to rear, and portion rotates away and locks thereat to become a seat for ride-on operation.
US11136087B2	Leaning vehicle An increase in the size of a leaning vehicle that has a double wishbone-type link mechanism is suppressed. A caliper is supported by a vehicle body frame. A disk includes: a disk contact part with which pads are allowed to be brought into contact; and a disk support part that, when the vehicle body frame is in an upright state, is supported by a support arm at a position that is further upward in an upward direction than an arm central shaft. When seen from a frontward direction, the disk support part supports the disk contact part so that an arm passing region through which a portion located between the arm central shaft in the support arm and a second end part of a left shock absorber and a second end part of a right shock absorber passes overlaps with the pads.
US11136084B2	Self-balancing scooter The present invention discloses a self-balancing scooter, including a scooter body, wheels, a driving motor, a power supply, a circuit board provided with a sensor, a controller and a light emitting lamp. The controller is electrically connected to the circuit board, the power supply and the driving motor respectively. The scooter body includes: an upper shell, pedals, a middle shell, a lower shell and a lampshade. The middle shell is located between the upper shell and the lower shell. The lampshade is provided with at least two spaced lamp strips for transmitting light. The scooter body is provided with lamp holes for placing the lamp strips. A quantity of the lamp holes is identical with a quantity of the lamp strips. Waterproof rings are sleeved on the lamps strips.
US11136080B2	System and method for mounting tailgate A system for automatically mounting a tailgate on a vehicle body includes: an X-direction regulation jig that measures an X-direction position of the tailgate and regulates the X-direction position; a Y-direction regulation jig that measures a Y-direction position of the tailgate and regulates the Y-direction position; a tailgate loading and mounting robot that corrects the X-direction position and the Y-direction position of the tailgate and mounts the tailgate on a side of a roof panel of the vehicle body; and a nut assembly robot that automatically assembles a nut to a hinge of the tailgate.
US11136078B2	Vehicle track shoe pad In some examples, a shoe pad for a grouser of a vehicle track defines a slot configured to receive a bracket that is configured to attach the shoe pad to a grouser. For example, a first arm of a bracket may be inserted into the slot and a second arm of the bracket may be configured to contact an interior side of a grouser of a vehicle track to attach the shoe pad to the grouser. In some examples, the shoe pad and the bracket may be held to the grouser with the aid of a bolt, which bolt may not extend through the grouser, but, rather, may merely engage with an exterior side of the grouser. In this way, the shoe pad may be able to be attached to a grouser without requiring one or more holes to be present in the grouser, while still providing a relatively tight fit with the grouser the shoe pad is configured to cover.
US11136077B2	Adjustable spare tire carrier Disclosed herein are embodiments of a spare tire carrier for a vehicle that can be adjustable for moving the spare tire into different positions. The spare tire carrier can be attached to existing components of a vehicle in order to move the spare tire's position, which can be advantageous for avoiding environmental hazards when off-roading.
US11136072B2	Cargo body with recessed logistics track A cargo body panel includes an interior side, an exterior side, a primary recess, a secondary recess positioned within the primary recess, and a logistics track. The interior side defines an interior plane. The exterior side defines an exterior plane. The primary recess includes a primary recess interior side defining a primary recess interior plane and a primary recess exterior side defining a primary recess exterior plane. The primary recess interior plane is recessed from the interior plane in a direction toward the exterior plane. The secondary recess includes a secondary recess interior side defining a secondary recess interior plane and a secondary recess exterior side defining a secondary recess exterior plane. A distance between the secondary recess interior plane and the interior plane is greater than a distance between the primary recess interior plane and the interior plane. The secondary recess exterior plane is non-coplanar with the exterior plane.
US11136067B2	Vehicle roof structure A vehicle roof structure has a roof panel and a roof side rail joined at a joint part that extends substantially in a vehicle body front-rear direction, and a recessed groove which opens to an upper side of the vehicle body and extends substantially along the vehicle body front-rear direction is provided in an upper part of the joint part. The roof side rail has a rail main part that is disposed on an outer side in a vehicle width direction of the roof panel across the joint part, and a rail extension part that extends forward from a front end part of the rail main part. The rail extension part is provided with a glass-receiving part that is disposed to be offset to the outer side in the vehicle width direction from the joint part when viewed from above, and receives the upper end side part of the windshield glass. The rail main part has a rail main face that forms the outer surface of the vehicle, and a shelf face that is provided in the front end part of the rail main face to be recessed downward, and to which a lower face of the side end part of the windshield upper molding abuts.
US11136066B2	Vehicle side body structure To improve bending rigidity of a side sill against an inward load during a lateral collision while suppressing a weight increase of the side sill, a vehicle side body structure includes a side sill that has a closed cross-sectional space extending in a vehicle longitudinal direction and a center pillar. A pillar inner provided in the center pillar has a pillar inner upper and a pillar inner lower. In a longitudinal direction of the side sill, an overlapping portion in which the pillar inner upper and the pillar inner lower overlap each other in side view in the closed cross-sectional space of the side sill is provided. The closed cross-sectional space further includes sections, each of which partitions the closed cross-sectional space in the longitudinal direction. These sections are joined to the overlapping portion and an inner surface, which faces the closed cross-sectional space, in the side sill.
US11136065B2	Extended roof reinforcement structure This disclosure relates to a motor vehicle, and in particular a vehicle body structure for a motor vehicle, with an extended roof reinforcement structure. An example vehicle includes an A-pillar, a roof side rail, a dash panel, and a reinforcement structure extending at least partially through the roof side rail and the A-pillar to a front end forward of the dash panel.
US11136064B2	Rotation detection device and steering system A rotation detection device includes a plurality of detectors each including a plurality of calculators respectively calculating a detection value. A control unit of the rotation detection device monitors abnormality of detection values respectively detected by the plurality of detectors, and, when determining abnormality, identifies a calculator calculating an abnormal detection value based on a result of comparison between the detection values of the plurality of calculators. Then, the control unit continues calculation of an absolute angle by using the detection values from the calculators other than the identified calculator.
US11136059B1	Contactless absolute rake position sensor for power adjustable columns Embodiments described herein are for a position sensor system integrated into a steering column assembly of a vehicle. The position sensor includes an elongated target comprising a sloping top surface, a first arcuate lateral surface, a second arcuate lateral surface, and an attachment feature for connecting the elongated target to a moveable part of the steering column assembly. The position sensor also includes a sensor device comprising an attachment feature for connecting the sensor device to a stationary part of the steering column assembly and a sensor situated over the sloping top surface of the elongated target. The sensor is configured to detect a position of the elongated target relative to the sensor, where the position of the elongated target corresponds to a position of a steering column of the steering column assembly.
US11136054B1	Lever assist for transport dolly A foot lever assist mechanism permits transport dollies to be more heavily loaded, saving the worker additional trips to deliver the entire supply. The lever assist is preferably secured to the axle using at least one boss. An auxiliary feature of this lever assist is the provision of a telescoping ladder-like extender for supporting beverage kegs. A toe grab allows the workman to tilt the stack of cases off of the hand truck's support platform and pull the bottom of the hand truck from beneath the load. Brakes are also provided to resist the hand truck's tendency to move rearwardly when tilting is attempted.
US11136046B2	Method and system of vehicle alarm that alarm area is changed by visible distance, and vision system for vehicle The present disclosure relates to a system and method of alarm for a vehicle. The present disclosure describes a alarm system for a vehicle for allowing a driver to practice a defensive drive in a weather environment which is hard to recognize the situation around the vehicle. An embodiment provides a alarm system for a vehicle including a camera operable to be disposed at the vehicle so as to have a field of view exterior of the vehicle, where the camera configured to capture image data, an image processor operable to process image data captured from the camera; a plurality of sensors disposed at the vehicle for sensing at least one of a front, side, or rear so as to capture sensing data, an alarm device for alerting a driver when detecting an object located in blind spot of the rear of the vehicle, and controller including at least one of processor configured to process at least one of (i) processing result of the captured image data and (ii) sensing data captured by the plurality of sensors.
US11136042B1	Assessing driver ability to operate an autonomous vehicle A method of assessing driver capability for operating an autonomous vehicle includes identifying, by one or more processors, a human operator of the vehicle, the human operator being associated with a driving capability profile. The method also includes determining human operator parameters associated with the human operator and determining an alertness level of the human operator based on the human operator parameters. The method further includes signaling, by a notification server of the vehicle, to the human operator with the signal, the signal requesting a response from the human operator. The method also includes updating, based on the response from the human operator to the signal, the driving capability profile to indicate a level of skill of the human operator at responding to the signal at the determined alertness level.
US11136037B2	Vehicle control device and vehicle control method In a vehicle control device and a vehicle control method, the vehicle control device comprises a lane recognition unit adapted to recognize a lane type of an adjacent lane adjacent to a host vehicle lane in which a host vehicle is traveling, a determination condition setting unit adapted to set a determination condition for permitting a lane change of the host vehicle from the host vehicle lane to the adjacent lane depending on the lane type of the adjacent lane that was recognized by the lane recognition unit, a lane change determining unit adapted to permit the lane change in the case that the determination condition is satisfied, and a vehicle control unit adapted to carry out a travel control or an assist control in relation to the lane change, in the case that the lane change determining unit has permitted the lane change.
US11136032B2	Vehicle and method for controlling the same A vehicle and a method for controlling the same are provided to induce inertial driving of a driver by guiding the inertial driving of the vehicle and controlling an accelerator pedal so that a pedal effort is applied to the accelerator pedal. The vehicle includes a display configured to display an object guiding the inertial driving, and a controller configured to apply a pedal effort to an accelerator pedal when guiding the inertial driving to induce the inertial driving.
US11136031B2	Motor-driven trailer and a method for controlling a motor-driven trailer A method for controlling a trailer driven by an electric motor comprises defining a distance between the trailer and a towing vehicle as a neutral position and determining an actual distance between the trailer and the towing vehicle. A deviation between the actual distance and the neutral position is determined and output as a distance value. The braking of the trailer is electrically-actuated when the actual distance is decreased relative to the neutral position by at least a first distance value. The braking of the trailer is mechanically-actuated when the actual distance is decreased relative to the neutral position by at least a second distance value, wherein the second distance value is greater than the first distance value. The trailer is accelerated by the electric motor when the actual distance is increased relative to the neutral position by a third distance value.
US11136030B2	Method and device for controlling vehicle, and storage medium The present disclosure provides a method and a device for controlling a vehicle. The vehicle is in a vehicle queue, the vehicle queue includes n vehicles {vehicle 0, vehicle 1, . . . , vehicle n−1} arranged in order along a traveling direction, the method is performed by a computing device of the vehicle i, i is from 1 to n−1. A vehicle-following subsystem model is established based on the relative speed and the relative vehicle distance error between the vehicle i and a vehicle i−1, and the acceleration of the vehicle i, a state trajectory of the vehicle-following subsystem model on a Δv-ΔR plane is determined, a plurality of division graphs of the vehicle i−1 in a plurality of travelling phases are combined to obtain a switching control graph for the vehicle i, and the travelling phase of the vehicle i is adjusted.
US11136029B2	Method for controlling a vehicle The invention relates to a method for controlling a subject vehicle (1) travelling along a road behind a vehicle transmitting wireless signals representative of at least one parameter affecting the velocity and/or acceleration of the transmitting vehicle (2), the method comprising—receiving said wireless signals from the transmitting vehicle (2), —controlling (S6) the velocity and/or acceleration of the subject vehicle (1) in dependence on the received signals, —during said control (S6) in dependence on the received signals, monitoring (S3) by means (111) other than means for wireless communication a distance (DSF) between the subject vehicle (1) and a further vehicle (3) travelling between the subject vehicle (1) and the transmitting vehicle (2), —and determining in dependence on the monitoring of the distance (DSF) between the subject vehicle (1) and the further vehicle (3) whether or not to control (S5) the velocity and/or acceleration of the subject vehicle (1) in dependence on the monitored distance (DSF).
US11136027B2	Vehicle control device This vehicle control device is provided with: a detection unit; and an external environment recognition unit that extracts a target object and left and right recognition lines of a traveling path. Additionally, a local environment map creation unit of the vehicle control device calculates an area of activity of an own vehicle and left and right border lines which indicate a limit of non-interference with the target object. Furthermore, the local environment map creation unit calculates left and right recommended border lines during traveling of the own vehicle by adding a margin interval that narrows the left and right border lines toward the inside.
US11136021B1	Independent control of vehicle wheels An over actuated system capable of controlling wheel parameters, such as speed (e.g., by torque and braking), steering angles, caster angles, camber angles, and toe angles, of wheels in an associated vehicle. The system may determine the associated vehicle is in a rollover state and adjust wheel parameters to prevent vehicle rollover. Additionally, the system may determine a driving state and dynamically adjust wheel parameters to optimize driving, including, for example, cornering and parking. Such a system may also dynamically detect wheel misalignment and provide alignment and/or corrective driving solutions. Further, by utilizing degenerate solutions for driving, the system may also estimate tire-surface parameterization data for various road surfaces and make such estimates available for other vehicles via a network.
US11136019B2	Method for monitoring a drive belt of a continuously variable transmission and method for preventing damage to the drive belt Monitoring is provided for a drive belt of a continuously variable transmission (CVT) mounted in a vehicle having a motor driving the CVT. A rotational speed of the motor and a power level of the motor are sensed. An abuse indicator for the drive belt is set when, concurrently, the rotational speed of the motor increases at a rate that exceeds a change threshold and the power level of the motor exceeds a power threshold. A level of abuse of the drive belt is calculated based on a speed of the vehicle and on a drive belt temperature. Damage to the drive belt may be prevented by limiting a power output of the motor when an accumulated level of abuse exceeds an abuse threshold. A vehicle having an electronic control unit configured to perform the method is also disclosed.
US11136010B2	Motor with a cone clutch motor brake A brake assembly comprising: (a) a caliper including: (i) one or more pistons, (b) one or more rotary to linear actuators that provides an axial force to move the one or more pistons, (c) a motor gear unit in communication with the one or more rotary to linear actuators, the motor gear unit including: (i) a motor; and (b) a motor brake that prevents movement of the motor gear unit, the pistons, or both when the motor is turned off so that a brake apply is maintained, the motor brake including: (i) housing; (ii) an engaging element; (iii) a sleeve, and (iv) a solenoid that is in communication with the sleeve so that when the solenoid moves the sleeve, the engaging element is moved into contact with the housing creating a braking force.
US11136007B2	Tire inflating device The present invention is an apparatus for tire inflation designed to allow users to properly inflate, maintain, and monitor the condition of vehicle tires. The tire inflation device of present invention is comprising of: a carrying case having a housing, a lid attached to the housing using a hinge, a plurality of locking latches to lock the lid over the housing and a handle configured over the lid to allow easy transport of the tire inflating device. The tire inflation device further comprises, a control head assembly to control the working of the device, an air compressor coupled with the control head assembly to provide compressed air for inflation of tires, a hose assembly to connect the device with the vehicle tires and a plurality of power adapters to connect the device with the power source. The control head assembly of the inflation device is further comprising of, a program control module, an auto level manifold, a plurality of output modules, an air release valve, a pressure release valve, a plurality of buttons and switches, and a display unit.
US11136006B2	Device for inflating a tire The invention is directed to a device for inflating a tire that includes a housing with at least one first connection port and at least one second connection port. The second connection port includes connecting means to interconnect the device with a pressure tank. The first connection port is fluidically connected to the second connection port by means of a fluid passage. Furthermore the device comprises a first valve. When a pressure tank is connected to the second connection port and when the first valve is in a closed state, the first valve is suited to prevent air from flowing from inside of the pressure tank out of the first connection port. When the first valve is in an open state, it is suited to allow passage of air from inside of the pressure tank through the fluid passage to the first connection port. The device further includes a second valve that is connectable to an inflator for pressurizing the tank.
US11136005B2	Vehicle wash system with side brushes having three or more axial orientations A vehicle wash system includes a vehicle treatment area and an overhead frame portion supporting a pair of side brushes. The side brushes are configured to treat the lateral sides of the vehicle and may also treat the front and back of the vehicle. The side brushes are configured to pivot between a vertical position, an outwardly angled position, and inwardly angled position. The side brushes may travel along the side of the vehicle in both the vertical and pivoted orientations. The side brushes may make multiple passes along the side of the vehicle, and the side brushes may change orientation during or between passes to treat different segments of the vehicle. The side brushes may be actively pivoted or may pivot in response to contacting the vehicle when shifted laterally into contact with the vehicle.
US11136004B2	Dual device cleaning apparatus Disclosed is a dual squeegee apparatus that may be sold to fuel station chains to replace the previous single squeegee designs, and thus offer patrons the ability to clean exterior automotive mirrors, lights and smaller windows in addition to the rest of the windows. This may enable fuel station chains to benefit from offering a competitive advantage to their customers to ideally secure more fuel sales and customer attention. This idea has very important benefits: It allows customers to clean the exterior of their vehicles mirrors, lights and smaller windows in addition to the rest of the windows. Never previously offered by any fuel station chains, and by facilitating extra customer service for the purchasing fuel station chains, this may in turn secure more sales and suggests increased profits.
US11136002B2	Wiper blade A wiper blade is presented having a wiper strip, a primary frame, and a pair of secondary frames. The primary frame having a connection device capable of connecting the wiper blade to a wiper arm disposed on a top side of the primary frame, and a connection structure disposed, on opposite ends of the primary frame. The pair of secondary frame, each have a central pivot connection portion and two leg portions extending from the central pivot connection portion, a pivot structure disposed on the central pivot connection portion of the secondary frames wherein the pivot structure of the secondary frames are connected to the connection structures on the ends of the primary frame. A wiper blade is also presented having a wiper strip, a force distribution structure having opposite ends, and a cover.
US11136000B2	Touch and gesture pad for swipe/tap entry verification system A system and method for providing access to a vehicle is provided. The system includes a plurality of capacitive sensors circumferentially spaced from one another in a circular arrangement defining a plurality of sensor nodes for receiving a touch input from a user in the form of a touch or a swipe. A controller unit is coupled to the plurality of capacitive sensors and a power source and is in communication with a plurality of vehicle systems and a latch mechanism. The controller unit detects a plurality of changes in capacitance of the plurality of capacitive sensors due to the touch input and determines whether the plurality of changes in capacitance matches a gesture sequence within a predetermined amount of time. The controller unit controls the latch mechanism in response to the communication with vehicle systems and changes in capacitance matching the gesture sequence within the predetermined amount of time.
US11135998B2	Seat belt for vehicle A seat belt for an occupant sitting on a seat in a vehicle includes a tongue part provided at a first side portion of the seat and a buckle part provided at a second side portion of the seat. The tongue part includes at least one first guide part that is operable between extended and contracted configurations, and at least one first webbing with a tongue wound therein. In addition, the tongue of the first webbing is connected with an end portion of the first guide part. The buckle part includes a second guide part that is operable between extended and contracted configurations, and the second webbing with a buckle wound therein. In addition, the buckle of the second webbing is connected with an end portion of the second guide part. The tongue of the tongue part is fastened to the buckle of the buckle part.
US11135997B2	Buckle device, seat mounting structure for buckle device, and vehicle seat belt device A buckle device includes: a buckle body to which a tongue portion mounted on a three-point seat belt is to be connected; a connecting member that is flexible and that has a first longitudinal end portion connected to the buckle body; and a force limiter mechanism including a take-up shaft around which a second longitudinal end portion of the connecting member is wound, the take-up shaft being supported below the buckle body in a vertical direction of a vehicle so as to be rotatable relative to a vehicle seat or a vehicle body, and an energy absorbing member that is deformed by rotation of the take-up shaft.
US11135995B2	Force-limiting device and seat belt system A force-limiting device, especially for a seat belt system (10) in a vehicle, has a force transducer (20) interacting with webbing (14) for which a normal webbing path is provided. The force transducer (20) includes a webbing track (30) that in a non-force-limiting position extends in parallel to the normal webbing path and in a force-limiting position extends inclined relative to the normal webbing path so that the force transducer (20) in the force-limiting position sets a predetermined extension force (F) required to move the webbing (14) vis-à-vis the force transducer (20) in a direction of belt extension (R).
US11135994B2	Pyrotechnical gas generator for an airbag A pyrotechnical gas generator includes at least one pyrotechnical charge, at least one ignitor, and a cylindrical casing enclosing the at least one charge and the at least one ignitor, the cylindrical casing having an axial direction and a radial direction and including an annular wall extending along the axial direction of the casing, and gas ejection holes arranged on the annular wall. Each gas ejection hole extends in a output plane forming a non-zero angle with a tangential plane which is tangent to the annular wall at the gas ejection hole.
US11135990B2	Accessory support systems and methods for landscaping equipment A method of using a support accessory rack includes aligning a first mounting portion of the support accessory rack with a first pin of a rollover protective structure. The method includes aligning a second mounting portion of the support accessory rack with a second pin of a second rollover protective structure. The method includes actuating the first pin to secure the first mounting portion to the rollover protective structure. The method further includes actuating the second pin to secure the second mounting portion to the rollover protective structure. The method includes pivoting a rotating support member of the support accessory rack away from the first mounting portion and the second mounting portion, and supporting the rotating support member onto a lateral bar of the rollover protective structure.
US11135989B2	Vehicle security divider The vehicle security divider can be installed in a back seat compartment of a vehicle to provide a confinement area in a portion of the back seat compartment for confining a passenger therein. The divider includes a front panel, a back panel, and a side panel. The side panel extends orthogonally to the front panel and the back panel. The divider includes brackets that are designed to secure the divider to anchoring points already present in a vehicle. Windows can be provided on or more of the panels to allow observation of the confined passenger.
US11135986B2	Vehicle body structure A bumper beam of a vehicle body structure (1) is provided with a laterally extending laterally middle part (55) and a pair of end parts (56) each extending from a corresponding lateral end of the middle part in an outboard direction with a certain inward slant with respect to a fore and aft direction, and each end part curves at a laterally middle point thereof so as to have a concave side facing outward with respect to the fore and aft direction.
US11135982B2	Interior trim of a motor vehicle An interior trim covers sections of door cutouts (1a, 1b) of a motor vehicle body facing a floor. The interior trim has a first trim panel (2a) for covering a section (3a) of the first door cutout (1a) facing the vehicle floor, a second trim panel (2b) for covering a section (3b) of the second door cutout (1b) facing the vehicle floor (31), and a third trim panel (8) that extends in the direction of the B pillar between the door cutouts (1a, 1b). The trim panels (2a, 2b, 8) compensate for tolerances during assembly of the interior trim so that the first and second trim panels (2a, 2b) can be shifted relative to each other in the longitudinal direction, and the third trim panel (8) and the first and second trim panels (2a, 2b) can be shifted relative to each other in the vertical direction.
US11135972B2	Heat index sensing system The subject invention relates to temperature and Heat Index sensing system, and in particular to a system suited for use in a K9 Police Vehicle that both monitors the temperature and heat index and provides an alert if pre-set maximum values are exceeded.
US11135970B2	Vehicle display device, method of controlling vehicle display device, and computer-readable non-transitory storage medium A vehicle display device mounted on a vehicle and configured to display an image to an outside of the vehicle includes: a self-luminous display unit configured to display an image to the outside of the vehicle by emitting light emitted from a light source to the outside of the vehicle; a reflective display unit configured to display an image to the outside of the vehicle by reflecting light from the outside of the vehicle; an information acquisition unit configured to acquire environment information indicating an environment outside the vehicle; and a controller configured to switch between image display by the self-luminous display unit and image display by the reflective display unit based on the acquired environment information.
US11135967B1	Large vehicle signaling system A large vehicle signaling system utilizing at least two signals in conjunction with the vehicle's lighting system to mirror the vehicle's brake and turn signals. The at least two signals may be attached to the rear face of the vehicle or brackets that allow them to pivot and move away from the rear face when not in use. The at least two signals should be positioned at a height of at least 80 inches from the ground so that they may be seen by a driver even if there are other vehicles between the driver and the large vehicle. When positioned in this way, the signaling system may allow for drivers of large vehicles to maneuver more safely as other drivers will be more aware of their signals.
US11135965B2	Optical axis control apparatus for headlight An optical axis control apparatus includes: an optical axis controlling unit for calculating, during stop of the vehicle, a pitch angle using an acceleration sensor provided in a vehicle and controlling, using the pitch angle, optical axis angles of headlights provided in the vehicle; and a rolling motion determination unit for determining, when the vehicle has started traveling, whether there has been a rolling motion during the stop of the vehicle. When the pitch angle has been changed during the stop of the vehicle and the rolling motion determination unit determines that the rolling motion exists, the optical axis controlling unit corrects, when the vehicle has started traveling and the rolling motion has been terminated, the amount change in pitch angle, using the amounts of correction set for each roll angle, and controls the optical axis angles using the corrected pitch angle.
US11135964B2	Apparatus and method for controlling intelligent headlamp An apparatus for controlling an intelligent headlamp may include: a capturing unit configured to capture a forward image of a vehicle; a lamp driving unit configured to independently drive LEDs of a headlamp configured as a matrix LED; a storage unit configured to store an initial origin point, a changed origin point and an offset for adjusting the position of the headlamp; and a control unit configured to control the lamp driving unit to turn on the headlamp, detect an origin point from the forward image inputted from the capturing unit, set the offset for adjusting the position of the headlamp by comparing the detected origin point to the initial origin point or the changed origin point stored in the storage unit, and store a changed origin point, newly set based on the detected origin point, and the offset in the storage unit.
US11135962B2	Modular system for a room, for a living, work or storage area, or for other three-dimensional spaces A modular flooring system comprises a modular floor surface and a plurality of stackable, three-dimensional modular interior design components (MIDCs). The modular floor surface can comprise an array of discrete, raised, low-profile, receiving panels that can be rectangular in shape. MIDCs can be securely and interchangeably placed on any group of one or more adjacent unoccupied receiving panel and they can also be stackable, such that various different floor layouts can be created. Each of the MIDCs may comprise a lower surface recess that fits over a group of one or more adjacent raised receiving panels. A first MIDC may have an raised lip on a top surface such that the lower surface recess of a second MIDC fits over, separately and interchangeably, one (or more) of the raised receiving panels and the raised lip on the top surface of the first MIDC. The MIDCs can comprise a storage cube MIDC (square or rectangular cube) as well as specialized MIDCs, such as a commode MIDC, a sink MIDC, a cooler MIDC, and a tile MIDC, etc. In such a manner, a user of the modular flooring system could locate the MIDCs on the floor surface and/or stack them to configure a preferred layout. Moreover, the MIDCs could be rearranged later to design a new layout.
US11135959B2	Dump trailer A dump trailer comprises a frame that is supported by at least one axle coupled to two wheels. The dump trailer includes a hitch operatively coupled to the frame and is configured to be attached to a tow vehicle. The dump trailer further includes a dump box pivotably coupled to the frame. The dump box has a front wall and is moveable between a lowered position and a raised position. The dump trailer also includes a storage unit supported by the frame and positioned adjacent to the front wall when the dump box is in the lowered position. The storage unit has at least one door and an interior configured to store items placed therein. The door is openable and the interior of the storage unit is accessible when the dump box is in either the lowered position or the raised position.
US11135957B2	Continuously adjusting headrest device A headrest adjustment mechanism is provided and includes a housing receptive of a rod and gripping jaws disposable in the housing to grip the rod such that the rod is securable and primarily adjustable in a height-wise dimension defined along a longitudinal axis of the rod and such that the rod is movable and pivotable in lateral dimensions defined transversely relative to the longitudinal axis of the rod.
US11135956B2	Vehicle console assembly with hinge assembly and method of assembly A vehicle console assembly with a hinge assembly includes a console body, an armrest lid, and a pivotable hinge assembly. The console body includes first and second spring arm engagement portions and a pair of slots. The armrest lid includes an armrest lid engagement portion. The pivotable hinge assembly includes a double torsion spring with a center linkage bar that extends outward between a pair of helical coil portions and between first and second hook locking features. The pivotable hinge assembly includes a hinge pin that extends through the pair of helical torsion coil portions of the double torsion spring to connect the pivotable hinge assembly to the console body.
US11135953B2	Seat back frame for vehicle A seatback frame for a vehicle is capable of preventing a passenger seated on a seat from being injured by a sharp edge of a side frame in the event of a collision of the vehicle. The seatback frame includes side frames installed to extend longitudinally in a vertical direction at opposite sides of the seatback frame, respectively, an upper frame joined to the side frames, and a lower frame joined to the side frames. Protrusions are formed at a surface of the upper frame while being spaced apart, by a predetermined distance, from edges present at edge portions of the side frames, respectively, to prevent the passenger from being injured by the edges.
US11135952B2	Cover adaptable to foldable vehicle seats A seat cover for a vehicle may include a lower or bench portion sized and configured to extend over a horizontally-oriented top of a bench of a vehicle seat. The lower portion may include a first section and a second section separated by a slit. The seat cover for the vehicle may also include an upper or backrest portion coupled to the lower portion. The upper portion may be sized and configured to extend upwardly over a backrest of the vehicle seat.
US11135950B2	Therapeutic technology fusion A system having a controller includes one or more thermal generation element assemblies, or a plurality of air bladder assemblies, or a plurality of electromagnetic coil assemblies, or a combination thereof, that are in communication with the controller and are configured for activation by the controller. The one or more thermal generation element assemblies, or the plurality of air bladder assemblies, or the plurality of electromagnetic coil assemblies, or a combination thereof are configured to provide a holistic mitigating effect on a vehicle occupant confined within the interior space of a vehicle for long periods of time.
US11135949B2	Seat with blower A seat comprises a seat cushion pad (20) including an air flow passage (21), and a blower connected to the air flow passage (21). The seat cushion pad (20) comprises a pad body (100), and a cover member (200) disposed on an upper surface of the pad body (100) to form the air flow passage (21) between the pad body (100) and the cover member (200). The cover member (200) comprises a first cover member (210) disposed on the upper surface of the pad body (100), and a second cover member (220) disposed on an upper surface of the first cover member (210). The first cover member (210) is fixed to the pad body (100), and the second cover member (220) is fixed to the first cover member (210) and to the pad body (100).
US11135946B2	Extensively reconfigurable vehicle seat design An extensively reconfigurable seat design can include a vehicle seat system including: a vehicle seat defining a vehicle occupant accommodating space, the vehicle seat including a seat cushion portion including multiple individually adjustable bladders, where each of the multiple individually adjustable bladders has a connected valve that controls fluid communication with an internal space of the individually adjustable bladder to adjust a pressure level within the internal space of the individually adjustable bladder, and an associated sensor configured to detect the pressure level within the internal space of the individually adjustable bladder. A computer can actively sense and control the pressure levels within the bladders, using the sensors and valves, to provide customization, adaptive, ride-active and intelligent control over a reconfigurable cushion for a vehicle.
US11135944B2	Vehicle seat A seat cushion is swingable about an axis A with respect to a seat cushion support frame that is a part of a main frame. A cushion return spring that is a flat spring is disposed between the seat cushion and the seat cushion support frame so that an elastic force of the cushion return spring returns the seat cushion to a neutral position. A pair of clamp rollers that clamps the cushion return spring is disposed. The clamp rollers are movable along a longitudinal axis of the cushion return spring. Changing of a clamping position by moving the clamp rollers changes an effective length of the cushion return spring. In this way, a swingable range of the seat cushion and a force to return the seat cushion to the neutral position are changed.
US11135943B2	Vehicle seat having internal support member A vehicle seat includes an internal support member for supporting a seat occupant. The internal support member includes a main body in plate or sheet form positioned within a seat cushion frame and first and second mounting portions engaged by first and second cross members of the seat cushion frame. A pressure sensor is mounted on a part of an upper surface of the internal support member which is closer to the first cross member than the second cross member. The main body of the internal support member is formed with a pair of openings positioned on either side of a central longitudinal line. A sensor mounting portion supporting the pressure sensor is defined between mutually adjoining edges of the openings. The first mounting portion includes a central first mounting piece which is positioned laterally centrally and has a greater width than the sensor mounting portion.
US11135941B2	Systems and methods for automated signaling for networked personal mobility vehicles The disclosed computer-implemented method may include automated signaling for networked personal mobility vehicles (PMVs). In some embodiments, a system may identify a PMV in use by a transportation requestor taking a trip. The system may also predict one or more actions of the PMV based on navigational data for the trip. Additionally, the system may select one or more signals corresponding to a predicted action of the PMV. In some embodiments, the system may determine, based on a current state of the PMV, that the predicted action of the PMV will be initiated within a time frame. Furthermore, the system may send a start command to the PMV to initiate a signal in response to determining the predicted action will be initiated. Various other methods, systems, and computer-readable media are also disclosed.
US11135939B2	System and method for hybrid-electric vehicle battery capacity estimation An electrified vehicle includes a powertrain that includes an engine and an electric machine. The vehicle includes a traction battery that is charged and discharged by operation of the engine and the electric machined. The vehicle includes a controller programmed to operate the engine and the electric machine to satisfy a driver power demand. The controller is also programmed to initiate an estimated of a capacity of the traction battery under predetermined conditions. The controller operates the engine and the electric machine to satisfy the driver power demand and charge and discharge the traction battery in a predetermined manner to create conditions favorable for estimating the capacity.
US11135936B2	Methods for using temperature data to protect electric vehicle battery health during use of bidirectional charger The present invention describes a method using temperature data to protect battery health during bidirectional charging in conjunction with monetization activities. The method includes receiving temperature data and determining anticipated energy needs of a building. The temperature data includes at least the temperature of one or more electric vehicle batteries or information required to determine the temperature of the one or more electric vehicle batteries while the anticipated energy needs are relative to ambient air temperature. The method includes determining an amount of discharge of the one or more electric vehicle batteries required to offset the anticipated needs of the building by a predetermined amount and determining based on the temperature data whether discharging the one or more electric vehicle batteries would be harmful to the health of the one or more electric vehicle batteries. The method includes discharging the one or more electric vehicle batteries to offset the anticipated needs of the building.
US11135935B2	Vehicle charging system An ECU included in a vehicle performs a first charging control when a minimum output voltage of a direct-current (DC) charger obtained through an information exchange process is less than or equal to a lower limit charging voltage for a power storage device, and performs a second charging control when the minimum output voltage is higher than the lower limit charging voltage of the power storage device. In the second charging control, initially, the ECU electrically connects a pre-charge circuit to a charging path from the DC charger to the power storage device, starts DC charging, and checks a voltage that is actually applied from the DC charger to the vehicle. If a voltage applied from the DC charger to the vehicle is a value corresponding to the voltage of the power storage device, the ECU permits the DC charging and performs the first charging control.
US11135933B2	Eco-friendly vehicle and charging control method therefor A charging control method of an eco-friendly vehicle for effectively determining an amount of charge of a battery for supplying power to a driving electric motor includes acquiring charging base information, determining a charging range depending on at least one of an upper charging limit or a lower charging limit using the acquired charging base information, and determining a target amount of charge within the determined charging range, wherein the determining of the charging range includes determining the upper charging limit based on an available charging time, and determining the lower charging limit based on a predicted remaining driving distance.
US11135931B2	System for charging a battery electric vehicle or a plugin hybrid vehicle using a mobile fuel cell A mobile fuel cell system includes a fuel cell generator generating a stack output signal. Multiple boost converter circuits converting the stack output signal into multiple recharge signals while in a first mode. A boost converter circuit converting the stack output signal into a local signal while in a second mode. Multiple charging handles connectable to multiple electric vehicles. A switch circuit presenting the recharge signals to the charging handles, remove the recharge signals from the charging handles and present the local signal while in the second mode. An auxiliary load may be connected to the fuel cell generator and the switch circuit. A rechargeable energy storage circuit powers the auxiliary load while in the first mode and stores energy received in the local signal while in the second mode. The auxiliary load is powered with the local signal while in the second mode.
US11135927B2	Four wheel drive vehicle A four wheel drive vehicle includes: main driving wheels and auxiliary driving wheels; a first driving motor that provides power to the main driving wheels; a second driving motor that provides power to the auxiliary driving wheels; a battery that stores electrical energy; an inverter that converts and provides the electrical energy stored in the battery to the first driving motor; and a bidirectional power converter that generates charging electric power for charging the battery by converting power supplied from the outside of the vehicle and converts and provides the electrical energy stored in the battery to the second driving motor.
US11135922B2	Control apparatus for rotary electric machine A system includes a rotary electric machine, wiring, a battery that is connected to the rotary electric machine by the wiring, and an upper limit value setting section which sets an output upper limit value that is an upper limit of an output command for the rotary electric machine. A control apparatus which controls the rotary electric machine is provided with a temperature acquisition section which acquires the temperature of at least one of the battery and the wiring, an allowable output value calculation section which calculates an allowable output value that is the upper limit allowed for the output command of the rotary electric machine, based on the temperature that is acquired by the temperature acquisition section, and a transmitting section which transmits the allowable output value calculated by the allowable value calculation section to the upper limit value setting section.
US11135921B2	Battery management method and apparatus Disclosed is a battery management method including calculating a safety of a battery unit based on physical quantity data of the battery unit, monitoring for a threshold adjusting event to occur, performing a comparing with respect to the calculated safety and a threshold based on the monitoring indicating that the threshold adjusting event has occurred, the comparing being based on reference information corresponding to the threshold adjusting event, and selectively performing a feedback process to output a feedback dependent on a result of the comparison.
US11135920B2	Adaptive operating device and method for adapting an operating device An adaptive operating device (1) for agricultural tractors includes two or more operating regions (2), each of which includes at least one manually operable operating element (3). The operating device (1) includes a detecting device (4) to detect the type of working apparatus (5) coupled to the tractor during use, a configuration device (6) cooperating with the detecting device (4) for configuring the functionality of an operating element (3) or operating region (2) for the type of coupled-on working apparatus (5), and at least one indicating element (7) of indicating a configuration of an operating region (2). Depending on the configuration, at least one operating element (3) can be changed with regard to its spatial position or can be configured with regard to direction or extent of movement.
US11135919B2	Steering wheel interface module with retained presets A steering wheel control interface module that can automatically detect the type of vehicle it is installed in and automatically detect the type of aftermarket radio it is sending messages to. In addition, the interface module can retain certain user pre-selects and use those to properly set the state of an aftermarket radio.
US11135918B2	Error detection IC of vehicle AV system The present disclosure relates to an error detection IC including: a first interface unit configured to receive a first signal for outputting a specific fixed image to a display apparatus provided in a vehicle; a memory in which data for one or more fixed images are stored; a signal processing unit configured to select a fixed image to be output to the display apparatus from among the one or more fixed images, based on the first signal, and to output a second signal for outputting the selected fixed image to the display apparatus; an image determination unit configured to provide a signal informing an error of the fixed image to a controller of the vehicle, when it is determined that the error exists in data for the selected fixed image included in the second signal, based on the data stored in the memory; and a second interface unit configured to provide the second signal to a display module.
US11135917B2	Forward collision avoidance display A head-up-display (HUD) device is disclosed and includes a plurality of light-emitting diodes (LEDs) configured to emit light beams in response to a control module of a vehicle generating a safety warning. The control module includes a processor that is configured to execute instructions stored in a nontransitory computer-readable memory. The HUD device also includes a first mirror that includes a transparent portion on a first side of the first mirror and a diffusive portion on a second side of the first mirror, and the light beams are configured to pass through the first mirror. The HUD device also comprises a second mirror that is configured to reflect the light beams toward a first reflective surface, and the second mirror is configured to reflect the light beams subsequent to the light beams passing through the first mirror.
US11135915B2	System and method for providing implement-based speed control for a work vehicle In one aspect, a system for providing implement-based speed control for a work vehicle may include a planter controller provided in operative association with a planter towed by the work vehicle and a vehicle controller provided in operative association with the work vehicle. The planter controller may be configured to access an input associated with at least one predetermined threshold value for an operating parameter of the planter and monitor the operating parameter relative to the predetermined threshold value(s) as the planter is being towed at a current ground speed of the work vehicle. In addition, when the operating parameter differs from the predetermined threshold value(s), the planter controller may be configured to adjust a speed control request transmitted to the vehicle controller to cause the current ground speed of the work vehicle to be automatically increased or decreased between predetermined maximum and minimum speed values set for the work vehicle.
US11135914B2	Drive axle for electric vehicles A drive axle of an electrically drivable vehicle including first and second drive wheels (R1, R2), first and second manual transmissions (G1, G2) and first and second electrical machines (EM1, EM2) which each have a respective drive shaft (1a, 1b). The first electrical machine (EM1) drives the first drive wheel (R1), via the first manual transmission (G1), and the second electrical machine (EM2) drives the second drive wheel (R2), via the second manual transmission (G2). The manual transmissions are each designed as three-speed transmissions (G1, G2) which have identical transmission ratios (i1, i2, i3).
US11135913B2	Fuel tank valve device A valve device includes: a housing having a valve chamber and a ventilation chamber divided by a dividing wall, the dividing wall having an opening, and the housing having a discharge opening formed at a peripheral surface on the ventilation chamber side; a float valve coming into and out of contact with the opening; and a fuel vapor pipe connected with the discharge opening outside the housing. The ventilation chamber is provided with a tubular wall which communicates with the discharge opening and which extends from the discharge opening toward the inside of the ventilation chamber. The tubular wall has a surface on the dividing wall side which is provided with a ventilation hole communicating with the ventilation chamber. An end portion on the extending direction side of the tubular wall is closed.
US11135910B2	Electric kart and battery An electric kart has a frame, a seat, four wheels, an electric motor operatively connected to two of the wheels, and at least one battery operatively connected to the electric motor. The at least one battery has a support structure mounted to the frame of the electric kart, and battery cells positioned on the support structure such that there is at least one air passage defined between the battery cells. Air passes through the at least one air passage when the electric kart is in motion to cool at least some of the battery cells. A battery for an electric kart is also disclosed.
US11135907B2	Bodywork for a two-wheeled vehicle A bodywork for a two-wheeled vehicle, in particular a scooter, has a roof element and a storage compartment. The roof element has at least two roof struts and a cover for the storage compartment. The roof element is mounted so as to pivot around an axis of pivot between at least two positions. In a first, lower position of the roof element, the roof struts are arranged in a stored position, the storage compartment has a reduced volume and is closed by the cover. In a second, upper position, the roof struts are arranged above a driver's seat and the storage compartment has an enlarged volume.
US11135905B2	Modular half door A side door assembly is provided for an automotive vehicle body having a side opening. The side door assembly includes a front casting for hinged connection to the vehicle body. A rear casting is also provided for latch connection of the vehicle door assembly to the vehicle. An extrusion and/or extrusions connect the front and rear castings providing a side door assembly that is extremely light, enhancing the ability of the driver to enjoy the vehicle.
US11135904B2	Door presenter with hold open and power cinching function A vehicle door presenting system includes an actuator striker positioned at one of a vehicle body surface or a vehicle door, and an actuator positioned at the other of the vehicle body surface or the vehicle door and engagable with the actuator striker. The actuator is configured to move the vehicle door between a fully closed position and a partially open position via interaction between the actuator and the actuator striker. The actuator includes a retaining portion to maintain engagement with the actuator striker. The retaining portion retains the vehicle door in the partially open position to prevent the vehicle door from moving toward a fully open position.
US11135900B2	Thermal request mediating device A thermal request mediating device includes a calculation unit configured to calculate amounts of heat for thermal circuits, a mediation unit configured to determine amounts of absorbed heat or amounts of discharged heat which are allocated to the thermal circuits based on amounts of heat transferable between the thermal circuits, and a distribution unit configured to distribute amounts of absorbed heat or amounts of discharged heat to units which are included in each thermal circuit based on the determined amounts of absorbed heat or amounts of discharged heat.
US11135899B2	Device, system and method for CO2 monitoring The present invention relates to a device, system and method for CO2 monitoring. To enable continuous monitoring at low cost and in a simple manner, the device comprises a signal input (10) for obtaining one or more monitoring signals (20) of a monitored area, a breathing monitor (11) for determining one or more breathing parameters (21) of one or more subjects present in the monitored area from the obtained one or more monitoring signals, and a CO2 estimation unit (12) for estimating the CO2 level (22) in the monitored area based on the determined one or more breathing parameters.
US11135897B2	Air duct system and measurement system and method for determining at least one parameter of an air flow emanating from an air outlet An air duct system for passing an air flow emanating from an air outlet to a measurement device for detecting parameter measurement values for at least one parameter of the air flow, includes at least one collecting unit for collecting the air flow emanating from the air outlet. That one collecting unit can be disposed on the air outlet so that a contact surface of the collecting unit encloses at least one outlet opening of the air outlet circumferentially. The collecting unit includes a wall defining a continuous air duct with an inlet end section and an outlet end section. In order to improve the measurement of the parameter of the air flow, the air duct system includes at least one measurement chamber that is communicatively connected to a section of the air duct enclosed by the inlet end section, which, as a measurement chamber that is otherwise closed relative to the surroundings, either contains at least one pressure sensor or comprises at least one connection for communicatively connecting the measurement chamber to a pressure measurement device.
US11135896B2	Heating, ventilation, and air conditioning system of a work vehicle A heating, ventilation, and air condition (HVAC) system of a work vehicle includes a housing configured to mount to a structure of a cab of the work vehicle. The housing includes at least one mounting assembly configured to support at least one heat exchanger within the housing, and the at least one mounting assembly is configured to position the at least one heat exchanger such that the at least one heat exchanger extends through the structure from an interior of the cab to an exterior of the cab while the at least one heat exchanger is coupled to the at least one mounting assembly.
US11135890B2	Position dependent damper for a vehicle suspension system A damper assembly for a vehicle suspension system includes a first damper and a second damper. The second damper includes a housing having a wall that at least partially surrounds at least a portion of the first damper, the volume between the wall and the first damper defining a chamber, and the wall defines an aperture. The second damper also includes a piston positioned within the chamber, a conduit defining a flow path that includes the aperture, and a flow control device disposed along the flow path. The second damper is configured to provide a damping force that varies based on the position of the piston within the chamber.
US11135889B2	Latch assembly for raising and lowering the height of a vehicle A latching assembly includes a lift housing extending along a center axis between a first and a second opened ends and defining a chamber extending therebetween. A support tube is disposed in the chamber and extends between a first and a second end. A moving member is disposed between the support tube and the lift housing for moving the lift housing between an extended position and a lowered position. The moving member includes an inner ring and an outer ring. The inner ring extends about the support tube. The outer ring is attached to the lift housing for translating an axial movement of the support tube into a rotational movement. A plurality of engagement members located between the inner ring and the outer ring for moving the inner ring and said outer ring axially along the center axis from the extended position to the lowered position.
US11135881B2	Trailer and a tow vehicle path optimization The invention is a system for optimizing a trailer path and a tow vehicle path. The system includes image sensors configured to capture images of a trailer and images of a path of travel both in front of and behind the trailer and tow vehicle, a weight determination system, accelerometers that sense acceleration of the tow vehicle and/or the trailer, a data input device configured to receive input data, and a processing device. The processing device includes a processor and non-volatile memory. The processor is configured to receive image data from the image sensors, receive weight data from the weight determination system, receive accelerometer data from the one or more accelerometers and receive the input data from the data input device. Additionally, the processor is configured to determine a trailer path and a tow vehicle path based on the image data, accelerometer data, and the input data. The processor is also configured to determine a safety parameter, communicate the trailer path and tow vehicle path to a user or vehicle control system, thereby prompting adjustments to the tow vehicle path and or acceleration when the trailer path or tow vehicle path is not optimum.
US11135878B2	Tire A tire 1 comprises a tread portion 2 comprising shoulder blocks 3 and crown blocks 4. The shoulder blocks 3 each has a ground contacting surface (3t) comprising an axially outer portion 6 extending axially inwardly from one of tread edges (Te) and a steeply oblique portion 7 extending axially inwardly from the axially outer portion 6 with a larger inclination angle with respect to the tire axial direction than the axially outer portion 6. The crown blocks 4 each has a ground contacting surface (4t) comprising a first oblique portion 10 inclined oppositely to the steeply oblique portion 7 and a second oblique portion 11 extending from and obliquely and oppositely to the first oblique portion 10. In a development view of the tread portion 2, longitudinal directions of the steeply oblique portion 7 and the first oblique portion 10 intersect at an angle from 70 to 110 degrees.
US11135867B2	Book block conveying device The device includes a first conveyor 1 and a second conveyor 12. The first conveyor transports the book blocks B to the bookbinding apparatus and can accumulate the book blocks on a transport surface 4. A first stopper 23 is arranged at an entrance of the second conveyor and a second stopper 28 is arranged in the middle of a path of book block on the transport surface of the first conveyor. The first and second stoppers can take a block position and a retracted position. The second conveyor and the first stopper operate in synchronization with an operation of the bookbinding apparatus. The second stopper takes the block position when the number of book blocks accumulated on upstream side of the first stopper exceeds a predetermined limit value, or when a thickness difference between the book blocks transported side by side exceeds a predetermined reference value.
US11135865B2	Method for producing printed matter A method for producing printed matter that includes applying one of a first pretreatment liquid and a second pretreatment liquid, the other of the first pretreatment liquid and the second pretreatment liquid, and then an aqueous ink, in this order, to a recording region of a substrate using an inkjet recording apparatus, wherein the first pretreatment liquid and the second pretreatment liquid are jetted so as to land on the substrate in a fixed order, the first pretreatment liquid contains a coagulant, and the second pretreatment liquid does not contain a coagulant, but contains a penetrant.
US11135862B2	Tape cassette with indicator portion having pressing and non-pressing portion for indentifying tape type A cassette case includes a bottom case and a top case. A tape is housed in the cassette case. A tape discharge portion discharges, from the cassette case, the tape that has been guided in the cassette case along a predetermined feed path. A first indicator portion indicates a type of the tape. A second indicator portion indicates a type of the tape, which is different from that indicated by the first indicator portion. An indicator member is a member independent from the top case and the bottom case, and is provided with the second indicator portion. An attachment portion is provided on the cassette case. The indicator member is removably attached to the attachment portion.
US11135861B2	Method for manufacturing printing apparatus, and printing apparatus A printing apparatus provided with a detection circuit executes: printing a first undercoat color on a printing medium; performing a calibration with respect to the printed first undercoat color; printing an adjustment pattern using a first pattern color that has a complementary-color relationship with the first undercoat color; detecting the adjustment pattern using the detection circuit; and making an adjustment based on the detected adjustment pattern.
US11135859B2	Grounding for media Some examples include a grounding system for an image forming apparatus. The grounding system includes a lifting plate having a top surface for storing media and an interface, a cable having a first end and an opposing second end, the first end attached at the interface, a retainer attached to the lifting plate at the interface, the retainer releasably securing the cable to the lifting plate, and a winding spool coupled to the second end of the cable, the winding spool to transfer torque to the cable and to accommodate a length of cable wound around the winding spool. Each of the lifting plate, the cable, and the winding spool are electrically conductive to release electrostatic energy from the media.
US11135857B2	Partially dried inkjet media conditioner A system for a partially dried inkjet media conditioner can include a heated pressure roller to apply pressure to a first side of partially dried inkjet media and apply heat to a second side of the partially dried inkjet media.
US11135855B2	Image forming apparatus, and non-transitory computer readable recording medium that records image forming program An image forming apparatus includes: a line head including multiple ink jet nozzles arrayed in a line direction; a storage device; and a controller circuit configured to determine an image width, the image width being a width of an image to be formed in the line direction, mandatorily eject ink from an ink jet nozzle group before forming the image, the ink jet nozzle group including multiple ink jet nozzles used to form the image having the image width out of the multiple ink jet nozzles, and store the image width in the storage device as a mandatory ejection width.
US11135850B2	Head cleaning device, inkjet image forming apparatus, and cleaning method A head cleaning device includes: a cleaning member that comes into contact with a nozzle surface of an inkjet head from which ink is ejected, and performs a cleaning operation of cleaning the nozzle surface; and a hardware processor that controls the cleaning operation, wherein the hardware processor brings the nozzle surface of the inkjet head heated and the cleaning member into contact with each other, the hardware processor maintains the contact until a temperature of the nozzle surface that has decreased to a temperature below a threshold due to the cleaning member being brought into contact therewith reaches a temperature equal to or higher than the threshold, and the hardware processor controls the cleaning operation after the temperature of the nozzle surface has reached a temperature equal to or higher than the threshold.
US11135845B2	Liquid discharge head, liquid discharge device, and liquid discharge apparatus A liquid discharge head includes a plurality of nozzles to discharge liquid, a plurality of pressure chambers communicating with the nozzles, a plurality of individual flow paths communicating with the plurality of pressure chambers, and a common flow path communicating with the plurality of individual flow paths. Further, each individual flow path includes a first flow path portion and a second flow path portion each having a fluid resistance higher than a fluid resistance of a pressure chamber of the plurality of pressure chambers that communicates with the individual flow path, and a third flow path portion disposed between the first flow path portion and the second flow path portion, the third flow path portion having a fluid resistance lower than the fluid resistance of the first flow path portion and the third resistance of the second flow path portion.
US11135843B2	Liquid ejection head In a liquid ejection head, an ejection pressure is applied to a pressure chamber for liquid ejection from a nozzle. A descender extends in a first direction and includes a first end connected to the pressure chamber and a second end. A communication passage is connected to the second end, extends in a second direction crossing the first direction, and has a first dimension in the first direction. The nozzle is positioned at the communication passage such that a shortest distance between an outer periphery thereof and a center of the second end is greater than 0.5 times a second dimension of the second end in the second direction. When viewed in the first direction, the center of the second end and a center of a cross-section defined by the nozzle to be orthogonal to an extending direction of the nozzle intersect an axis of the communication passage.
US11135842B2	Piezoelectric element, liquid ejecting head, and printer A piezoelectric element includes a first electrode disposed at a base body, a second electrode, and a piezoelectric layer disposed between the first electrode and the second electrode. The piezoelectric layer includes a first piezoelectric layer containing a complex oxide having a perovskite structure that contains lead, zirconium, and titanium and a second piezoelectric layer containing a complex oxide having a perovskite structure that is denoted by formula (1) below. The first piezoelectric layer is disposed between the first electrode and the second piezoelectric layer and is preferentially oriented to (100) when the crystal structure of the first piezoelectric layer is assumed to be pseudo-cubic, xPb(Mg,Nb)O3-yPbZrO3-zPbTiO3 (1) where in formula (1), 0
US11135841B2	Liquid discharge head and manufacturing method of the same A liquid discharge head includes a discharge port member including a discharge port, a flow path member including a pressure chamber and a liquid flow path, a substrate, and a structure that is arranged on the substrate on an upstream side of a center of the discharge port and that is configured to generate a flow of the liquid toward the discharge port. The liquid in the pressure chamber circulates. A position corresponding to a portion of the structure having a greatest height from a surface of the substrate is located on the upstream side of the center of the discharge port in a flow direction of the liquid. A thickness of the structure in a discharge direction of the liquid is 0.1 times or greater than a thickness of the liquid flow path in the discharge direction of the liquid.
US11135835B2	Ejection control using substrate alignment features and print region alignment features In a printing method, at least one image of a substrate supported in a printing system is acquired. An actual position of a first alignment feature on the substrate in a frame of reference of the printing system is determined based on the at least one image. Expected positions of second alignment features on the substrate are determined based on the actual position of the first alignment feature. Actual positions of the second alignment features in the frame of reference of the printing system are determined based on the at least one image and the expected positions of the second alignment features. Target positions of print regions on the substrate are determined based on the actual positions of the second alignment features. Ejection of print material onto the substrate in the print regions is controlled based on the target positions of the print regions.
US11135834B1	Interferential patterns for printer calibration Certain examples describe a method of calibrating a printer and a printing system. An interferential pattern is printed in the form of a print calibration image on a print medium. Data representative of the interferential pattern as printed on the print medium is detected using an optical sensor. The printer is calibrated based on the captured data. The interferential pattern is based on a waveform that varies in amplitude along an axis perpendicular to a printing axis under calibration and has repeated sets of multiple patterns based on the waveform, the repeated sets having a varying pattern spacing in the printing axis under calibration.
US11135830B2	Sinterable feedstock for use in 3D printing devices The present invention relates to a filament suitable to be used in a 3D printing device, wherein the filament comprises a metal and/or ceramic powder, a thermoplastic binder and additives. The invention also relates to a process for producing a shaped body comprising the step of printing a shaped green body using the filament according to the invention. Also provided is the use of a filament according to the invention in a 3D printing device and a green body producible by mixing a metal and/or ceramic powder and a thermoplastic binder. The invention also relates to the use of a binder of the invention for the production of a filament for 3D printing devices.
US11135825B2	Metal/fiber-reinforced resin material composite body and method for producing same According to the present invention, a surface of a prepreg (104), said surface being provided with a partially fused structure (102A), and a surface of a metal member (110) are brought into contact with each other, and heat and pressure are subsequently applied thereto. After completely melting a resin containing a thermoplastic resin and adhering to the prepreg (104) so that a reinforcing fiber substrate (101) is impregnated with the molten resin, the resin is cured to obtain a matrix resin (105), thereby forming a CFRP layer (120) that serves as a fiber-reinforced resin material, and the CFRP layer is simultaneously compression-bonded to the metal member (110), so that a metal-CFRP composite body (100) in which the CFRP layer (120) and the metal member (110) are firmly bonded to each other is formed.
US11135823B2	Method of laminating absorbable semi-crystalline polymeric films The invention relates to novel processes for the lamination of semi-crystalline, high-melting point, low glass transition polymeric films, which are extruded and subsequently laminated on various thermally sensitive substrates to form laminated medical device constructs in a specific time interval to allow low processing temperatures to avoid polymer film and/or substrate degradation or heat-related distortions. Also disclosed are laminated medical device constructs made from such processes.
US11135820B2	EVOH-coated, biaxially oriented, high-density, polyethylene films with metal-oxide deposition Disclosed are compositions and methods for multilayer films, which, in one embodiment may include a core layer comprising a polyethylene stabilizer optionally in a masterbatch solution and at least 50 wt. % of high-density polyethylene. Further, the multilayer film may include a first skin layer comprising at least 90 wt. % ethylene-propylene polymer and antiblock, and a second skin layer consisting of an ethylene-propylene copolymer or terpolymer. Further still, the multilayer film may include a primer layer on the second skin, an aqueous barrier layer of ethylene vinyl alcohol polymer, polyvinyl alcohol polymer, or combinations thereof on the primer layer. And, further still, multilayer film may include a metallization layer on the aqueous barrier layer, wherein the multilayer film may be oriented in at least one direction.
US11135816B2	Vehicle components formed with epoxidized chopped glass bonded to a thermoset matrix A process is provided for molding a resin matrix around a distribution of well distributed epoxy coated glass fibers to produce an article. The article is mass produced by the molding process based on a one or more layer structure, with an outer panel having a high degree of surface smoothness common to automotive body panels and a comparatively high tensile strength joinder thereto. The epoxy coated glass fibers are present in a single panel of an article or all such panels of a multiple layer article. The epoxy coated glass fibers can be present in an articles in a form of: chopped glass fibers that are intermixed and vary in orientation, a woven roving containing predominately epoxy glass fibers with carbon fibers dispersed there through, or non-woven fiber mats.
US11135814B2	Method of producing a building panel and a building panel A method of producing a building panel, including: providing a core, applying a balancing layer having a first moisture content on a first surface of the core, the balancing layer comprising a sheet impregnated with a thermosetting binder, applying a surface layer having a second moisture content on a second surface of the core, the surface layer comprising a thermosetting binder, adjusting the first moisture content of the balancing layer such that the first moisture content of the balancing layer is higher than the second moisture content of the surface layer prior to curing, and curing the surface layer and the balancing layer by applying heat and pressure. Also, a semi-finished product adapted to be cured for forming a building panel.
US11135813B2	Wood-based material insulated for combustion resistance A fire retardant article has a wood-based material with a polyisocyanurate foam article attached thereto, where the polyisocyanurate foam article covers 90% or more of the exposed portion of the wood-based material, has a thickness greater than 1.8 centimeters, a foam core having a density of 28-128 kg/m3, a trimer concentration characterized by at least one of (i) a trimer level in a range of 12-25 weight-percent and (ii) a molar ratio of trimer to sum of urethane and urea in a range of 1-8, a phosphorous concentration of at least 0.3 wt %, a combined concentration of phosphorous and bromine of at least 0.5 wt %, and a vapor permeable and non-combustible facer on at least one primary surface of the foam core.
US11135811B2	Interlayer for laminated glass, and laminated glass An interlayer film for laminated glass having a one-layer structure or a two or more-layer structure includes a first layer containing a polyvinyl acetal resin and a plasticizer, wherein the first layer further contains silica particles, and the ratio of a content of the silica particles in the first layer to a total content of the polyvinyl acetal resin and the plasticizer in the first layer is from 0.03 to 0.4.
US11135809B2	Thermally-bondable multi-layered composite film for manufacturing outdoor clothing, and method for manufacturing same Provided are a multi-layered composite film that may be thermally-bonded to a fabric by using a hot melt adhesive that is dot-coated on the surface thereof, and a method of manufacturing the same. In particular, the present invention relates to: a thermally-bondable multi-layered composite film which can be used in the manufacture of outdoor clothing, has excellent breathability and waterproofing properties, and can simplify the process of manufacturing the outdoor clothing; and to a method for manufacturing same.
US11135808B2	PET release liner A multilayer release liner for use in a roofing system, that includes a roofing membrane and an asphalt or bitumen adhesive. The multilayer release liner contains a core layer including PET, surrounded by several outer layers including at least two tie layers adhered to the core layer, and at least two polyolefin layers adhered to the tie layers. The multilayer release liner of the present invention is highly compatible with silicone and does not contain any ingredients that may interfere with the adhesion or cure of a silicone coating. The liner of the present invention also provides an effective oil barrier and minimizes oil migration and discoloration of the multilayer release liner from the adhesives used in roofing systems.
US11135807B2	Filler-containing film A filler-containing film has a structure in which fillers are held in a binder resin layer. The average particle diameter of the fillers is 1 to 50 μm, the total thickness of the resin layer is 0.5 times or more and 2 times or less the average particle diameter of the fillers, and the ratio Lq/Lp of, relative to the minimum inter-filler distance Lp at one end of the filler-containing film in a long-side direction, a minimum inter-filler distance Lq at the other end at least 5 m away from the one end in the film long-side direction is 1.2 or less. The fillers are preferably arranged in a lattice form.
US11135804B2	Film for display device and display device including the same A display device according to an exemplary embodiment includes: a display panel that includes a substrate and an emission layer; and a support film that overlaps the display panel, the display panel and the support film including a bending area, and the support film including a first groove disposed in the bending area and a first crack prevention layer disposed in the first groove.
US11135803B2	System for impressing a relief pattern on a substrate A die and counter die system for impressing a relief pattern onto a substrate, including at least one male die including a contact surface and defining a relief pattern, a compressible counter film including a base layer, a contact layer disposed opposite the contact surface of the at least one male die and spaced therefrom, and a compressible layer disposed between the base layer and the contact layer and attached thereto. The contact layer is featureless in a region thereof opposing the relief pattern on the at least one male die. The compressible counter film has a compressibility, in a direction perpendicular to a broad face of the compressible counter film, in the range of 5-30% at 1.35 MPa. The system further includes a compression mechanism adapted to move the at least one male die and the compressible counter film towards one another in an operative mode.
US11135795B2	Joining apparatus and joining method for a cord ply for a tire Cord ply joiner for a tire includes a first pressurizer having first pressing member and first pressure receiving member in upper and lower sides, and a second pressurizer having second pressing member and second pressure receiving member in the upper and lower sides. A first code ply positioning mechanism positions a first code ply by bringing a tail end of the first code ply into contact with a side surface of the second pressure receiving member, a first code ply fixing mechanism lowers the cord end pressing member so the first cord ply is fixed, and a second code ply positioning mechanism positions the tip of the second code ply by bringing the tip into contact with a side surface of the cord end pressing member. The first pressurizer and the second pressurizer are brought close to each other, whereby a shearing force is applied to an overlapped portion.
US11135793B2	Method for filling surface imperfections in an aircraft wing A filling method for filling surface imperfections on a surface of a wing comprising a scanning step in which a control unit controls a movement of a scanner past the surface of the wing to scan the surface and transmit the collected data to the control unit, a computation step in which the control unit computes a digitized surface from the data, a determination step in which the control unit determines each surface imperfection by comparing the reference surface and the digitized surface, a generation step in which the control unit generates a digital model of the patch intended to fill the surface imperfection, and a printing step in which the control unit controls the movement of a 3D printer past each surface imperfection and commands the activation of the 3D printer in order to make it print the patch.
US11135791B2	Glass restoration apparatus and method A damaged glass surface restoring tool comprises a replaceable, hermetically sealed container of glass fluid restoring substance aligned within a vacuum chamber perpendicularly to the glass surface. A method of restoring a damaged glass surface creates a vacuum in a chamber aligned over a crack in the glass and applying to the crack a glass restoring substance before being exposed to external air in a straight line path of application.
US11135789B2	Methods and devices of forming a tensioned stringer for a vehicle Methods and devices of fabricating a stringer for a vehicle. The stringer can be constructed from two charges that are formed together into the stringer. During fabrication, the charges are placed over support members with the ends of each charge extending over a die cavity. The charges are secured and a punch die forces the first ends into the die cavity forming blades of the stringer. The charges are secured thus tensioning the charges during the punch process.
US11135788B2	System of continuous pultrusion method for manufacturing of bio-composite products; process and products thereof Bio-composite pultruded products (100, 104, 107, 110, 114, 117) either in “I” profile or “Plate” profile of higher cross sectional area where said products consisting essentially natural fibres selected from hemp, jute, sisal and. flex as core impregnated with a resin system comprise of at least one resin, curing system comprising a curing agent and an accelerator, a filler, a thinner, pigment or any other additives; encapsulated between bi-directionally and/or uni-directionally oriented synthetic fabric selected from polyester, carbon, aramid, glass, basalt and mixtures thereof impregnated with said resin system are provided. in another bio-composite pultruded products either of “I” profile or “Plate” profile of higher cross sectional area where said products consisting of plank of short fibers bagasse premixed with the said resin system as core is enclosed between the natural fibers selected from hemp, jute, sisal and flex impregnated with the resin system which is further enclosed between bi-directionally and/or uni-directionally oriented synthetic fabric selected from polyester, carbon, aramid, glass, basalt and mixtures thereof impregnated with the resin system. The system and method for the preparations of said bio-composite pultruded products, are also illustrated herein. These products lead to a significant reduction in weight and reduction in density with higher stiffness and bending strength. The present bio-composite products are encapsulated by fabrics in the peripheral area brings more integrity uniformity of jute materials. This leads to a significant cost reduction in a without sacrificing much tensile strength.
US11135786B2	Adding a segment of fiber-reinforced thermoplastic filament in a curve In additive manufacturing, a method of adding a segment of fiber-reinforced thermoplastic filament. Adding a segment of filament involves three tasks: (1) determining where the segment of filament should be added, (2) depositing the segment of filament at the desired location, and (3) tamping the segment of filament to ensure adhesion and eliminate voids. Tamping the segment of filament is performed by steering a wheel along the filament. In accordance with the illustrative embodiment, the wheel is steered around a yaw axis that is offset from the wheel's axis by a distance s, where s is a positive real number.
US11135782B2	Manufacturing method and device of carbon fiber sheet molding compound Provided is a method of manufacturing a carbon fiber sheet molding compound, the method including: performing sizing treatment on a carbon fiber using a sizing agent; cutting the sizing-treated carbon fiber into pieces; spraying the pieces of carbon fiber onto a first resin coated on a surface of a first carrier sheet; and uniting together a second resin coated on a second carrier sheet and a surface of the first resin, wherein the sizing agent, the first resin, and the second resin include the same compounds.
US11135777B2	Poylmeric composition for use as a temporary support material in extrusion based additive manufacturing The polymeric composition of this invention can be used as a temporary support material in the additive manufacturing of three dimensional articles without compromising the quality of the ultimate product, reducing printing speed, increasing cost, increasing the incidence of printer jamming, or requiring printers of increased complexity. This invention more specifically discloses a polymeric composition which is particularly useful as a temporary support material for utilization in three-dimensional printing, said polymeric composition being comprised of a first polymeric component which is suitable for use as a modeling material and a second polymeric component which is immiscible with the first polymeric component, wherein the polymeric composition has a continuous phase, wherein the continuous phase is comprised of the second polymeric component, and wherein the polymeric composition has a Shore A hardness of at least 80.
US11135771B1	System and method of manufacturing a medical implant A system and method for forming a medical implant using a printing device. The printing device includes a print head having a heated nozzle, a heated build plate for receiving the printed material thereon, and a reflective plate having an active heater. A method for forming a medical device includes extruding a printing material by contiguous deposition to form a porous object having a lattice-like structure. The medical device, such as a spinal implant, may have interconnected pores and different regions, each having a different porosity for encouraging bone growth therein. The printed medical implant may be designed to be patient-specific, customized, and printed on-demand.
US11135768B2	Production system for the simultaneous additive manufacturing of several components Methods of additively manufacturing components include providing a first control command and/or a second control command to a cart selected from among a plurality of carts. The first control command may be configured to cause the selected cart to autonomously drive or fly to a construction container selected from among a plurality of construction containers and to receive automatically the selected construction container, and, upon the selected cart receiving automatically the selected construction container, to autonomously drive or fly the selected cart to a construction apparatus selected from among a plurality of construction apparatuses. The second control command may be configured to cause the selected cart to autonomously drive or fly to the selected construction apparatus and to receive automatically a construction container containing a component having been additively manufactured by the selected construction apparatus upon the selected construction apparatus automatically discharging the construction container containing the component.
US11135766B2	Products containing nylon 6 produced by stereolithography and methods of making the same Provided herein according to some embodiments is a method of forming a three-dimensional object comprising nylon 6 by additive manufacturing, as well as objects so produced. Also provided is a polymerizable liquid composition useful for producing a three-dimensional object comprising nylon 6 by additive manufacturing, which composition may include: (a) a light polymerizable first component, and (b) a heat polymerizable second component; said heat polymerizable second component comprising: (i) caprolactam monomers, (ii) a catalyst for anionic polymerization of caprolactam, and (iii) an initiator for anionic polymerization of caprolactam.
US11135764B2	Additive manufacturing system implementing hardener pre-impregnation A method is disclosed for additively manufacturing a composite structure. The method may include directing a continuous reinforcement into a print head, and coating the continuous reinforcement with a first matrix component inside of the print head. The method may further include coating the continuous reinforcement with a second matrix component, discharging the continuous reinforcement through a nozzle of the print head, and moving the print head in multiple dimensions during the discharging. The first and second matrix components interact to cause hardening of a matrix around the continuous reinforcement.
US11135762B2	Shaped article, and manufacturing method for the shaped article A manufacturing method for a shaped article is provided and includes manufacturing the shaped article by stacking a plurality of layers on one another, wherein the shaped article comprises a light reflective layer, being formed from an ink having light reflectiveness; a decorative layer; and a transparent layer, being formed from a transparent ink, wherein the decorative layer is formed on an outer side of the light reflective layer, and the transparent layer is formed on an outer side of the decorative layer; and a layer forming process, forming a part of the transparent layer and a part of the decorative layer in this order from an end side toward a center side of at least two of the plurality of layers.
US11135760B2	Process for forming articles from extruded polymer sheet Method for forming a transparent article comprising: heating a polymer sheet 40 to form a heated sheet; creating a pressure differential across the heated sheet; pushing the heated sheet onto the contoured surface 20 to form a shaped article; and releasing the shaped article from the mold 12. Also included herein are articles made therefrom.
US11135756B1	Composite useful for molded articles A wearable container containing a composite which has an alternating pattern containing groupings of woven fabric and groupings of biaxially oriented thermoplastic films. The composite has a thickness of less than about 5 mm. Each grouping of woven fabric contains at least one woven fabric layer, each woven fabric layer containing tape elements having a base layer of a strain oriented olefin polymer disposed between covering layers of a heat fusible olefin polymer. Each grouping of biaxially oriented thermoplastic films contain at least one biaxially oriented thermoplastic film which has a core layer of thermoplastic disposed between covering layers of a thermoplastic able to bond to polypropylene.
US11135755B2	Laminate, molded article in which laminate is used, and method for manufacturing same A method of manufacturing a molded article, which comprises: (a) a step of manufacturing the molded article by use of a laminate that has a first layer comprising polypropylene, and a second layer comprising one or more selected from the group consisting of polyethylene, polyamide, an ethylene-vinyl alcohol copolymer, and an ethylene-vinyl acetate copolymer.
US11135749B2	Filling apparatus for foamable material and filling method therefor In order to provide a filling apparatus which is capable of advantageously delivering a foamable material having a necessary amount into a closed cross section of a vehicle body, in an embodiment of the present invention, there is provided a filling apparatus for filling a closed cross section of a vehicle body with a foamable material is provided, wherein the foamable material is a foamable two-liquid polyurethane material, wherein the filling apparatus comprises a delivering part for delivering the foamable material into the closed cross section of the vehicle body, and wherein the filling apparatus further comprises an input part into which a delivery command value and correction values to set a real delivery amount are input.
US11135734B1	Compact hand axe Compact hand axe that can chop along multiple axes is disclosed. While utilizing the tool in the hand axe configuration the forward-facing, mid-grip trigger allows for axial rotation to occurs in user's hand around the middle finger, enabling it to achieve a far greater edge velocity/impact than would ordinarily be expected from a blade of this length. Furthermore, working in conjunction with the channeled mounting wedge, the trigger also enables the present hand axe to be mounted securely to a haft of the users choosing so that the tool's broad front edge can provide the functional yield of a full-size, dedicated axe.
US11135733B2	Shaving device A device for shaving and dispensing material therefrom. The shaving device has a shaving head removably attached to a handle. The shaving head includes at least one blade to allow a user to cut hair. The handle has an internal cavity, wherein the internal cavity can be separated into two parts to allow insertion of a capsule containing a dispensable material, such as shaving cream or aftershave. The handle includes an opening adjacent to the shaving head and an outlet at the opposing end of the handle. The opening and the outlet allow the material from the capsule to be dispensed therethrough. The dispensable material may be dispensed at will by the user.
US11135731B2	Cutting device having a locking member A cutting device is disclosed. The cutting device has a housing and a carriage that is movably disposed in the housing, the carriage being movable between a retracted position and an extended position. The cutting device also has a cutting member that is removably disposable in the carriage and a cover member that is removably attachable to the housing. The housing has a locking member. When the carriage is in the extended position and the cover member is attached to the housing, the locking member locks the cover member to the housing. When the cutting member is disposed in the carriage in the extended position, the cutting member is retained in the housing by the locked cover member.
US11135727B2	Autonomously acting robot that performs a greeting action Empathy toward a robot is increased by the robot emulating human-like or animal-like behavior. A robot includes a movement determining unit that determines a direction of movement, an action determining unit that selects a gesture from multiple kinds of gesture, and a drive mechanism that executes a specified movement and gesture. When a user enters a hall, an external sensor installed in advance detects a return home, and notifies the robot via a server that the user has returned home. The robot heads to the hall, and welcomes the user home by performing a gesture indicating goodwill, such as sitting down and raising an arm.
US11135726B2	Autonomously acting robot that accepts a guest A guest robot acquires a right of access to a resource a host robot can access after accreditation by the host robot. The host robot accredits the guest robot on condition that the guest robot is positioned within a predetermined distance. The guest robot receives behavioral characteristic information from a server that determines behavioral characteristics of the host robot, and selects a motion in accordance with the behavioral characteristic information. A behavioral restriction that is not imposed on the host robot may be imposed on the guest robot.
US11135725B2	Robot control system, robot control method and user apparatus for robot control system A robot control system, including: a mobile robot having a situation-detecting unit detecting surrounding situations; a user apparatus operating in a manner recognizable by a user based on signals detected by the situation-detecting unit; an action-detecting unit detecting a predetermined action of the user; a brain-activity-detecting unit detecting a brain activity of the user; and a robot-controlling unit controlling the robot. The user apparatus has a computing unit analyzing the brain activity of the user detected by the brain-activity-detecting unit to output a first-action instruction from the user to the robot. The robot controlling unit further controlling the robot in accordance with the first-action instruction output by the computing unit and controlling, when the predetermined action is detected by the action-detecting unit during operation of the user apparatus, the robot in accordance with a second-action instruction different from the first-action instruction output by the computing unit.
US11135720B2	Method and system for programming a cobot for a plurality of industrial cells Systems and a method are provided for programming a cobot for a plurality of cells of an industrial environment. A physical cobot is provided within a lab cell comprising physical lab objects. A virtual simulation system receives information inputs on a virtual cobot representing the physical cobot, regarding a virtual lab cell comprising virtual lab objects, and on a plurality of virtual industrial cells comprising virtual industrial objects. Inputs are received from the physical cobot's movement during teaching whereby the physical cobot is moved in the lab cell to the desired position(s) while providing, via a user interface, a visualization of the virtual cobot's movement within a meta cell generated by superimposing the plurality of virtual industrial cells with the virtual lab cell, so that collisions with any object are minimized. A robotic program is generated based on the received inputs of the physical cobot's movement.
US11135716B2	Minimally actuated serial robot The present invention relates to a robot device comprising a chain comprising a plurality of fixedly connected links and a mobile actuator movable thereon configured to change a position of a link relative to a position of an adjacent link; wherein said mobile actuator comprises at least a first motor to drive it along said chain of connected links; and wherein said mobile actuator is engageable with a position-determining element in said link.
US11135715B2	Robot arm A robot arm permitting a more sensitive and precise operation in the offline programming of a robot having a robot arm with a number of arm components, which can be connected to a robot body via a number of actuator-drivable joint connections.
US11135713B2	Socket holding frame assembly A socket holding frame assembly has a track base, multiple holding bases, and multiple fasteners. The track base has a bottom panel, a track channel, and a connection portion. The track channel is defined in the bottom panel. The connection portion is formed through the bottom panel. The holding bases are mounted slidably and rotatably in the track channel in the track base. Each holding base has a connection hole defined in a bottom of the holding base. The fasteners are mounted through the connection portion in the bottom panel from a bottom surface of the bottom panel and are screwed respectively into the connection holes in the holding bases.
US11135712B2	Driving tool A driving tool drives a fastener by a striking mechanism. The driving tool includes a trigger, a contact arm, a contact lever and a regulator. The trigger and the contact arm receive manipulations which operate the striking mechanism. The contact lever is movable according to operations of the trigger and the contact arm and switches operating states of the striking mechanism. The regulator regulates a movement of the contact lever according to a movement of the contact arm in which another manipulation is released. The regulator operates with a fluid for operating the striking mechanism, and keeps the contact lever at an operation standby position where the contact lever is operated by manipulation of the contact arm for a predetermined time period by controlling a flow rate of the fluid.
US11135706B2	Industrial tool and drive system for same A drive system for an industrial tool (e.g., a hydraulic torque wrench) includes a cylinder, a first piston, a first rod, a second piston, and a second rod. The cylinder includes a first end, a second end, and a longitudinal axis extending therebetween. The first piston is disposed within the cylinder and movable along the longitudinal axis. The first rod is coupled to the first piston and extends toward the first end of the cylinder. The second piston is disposed within the cylinder and movable along the longitudinal axis. The second rod is coupled to the second piston and extends toward the first end of the cylinder.
US11135705B2	Adapter for turning a knob and methods for making and using the adapter Adapters for use with a driving device for turning a knob, and methods for making and using such an adapter are provided. In one example, an adapter includes a shaft that extends distally from a proximal end portion to a distal end portion and that defines a longitudinal axis. The proximal end portion is configured to operatively couple to the driving device for rotating the shaft about the longitudinal axis. An adapter body is coupled to the distal end portion of the shaft. At least one engaging member is disposed radially outward from the longitudinal axis and is configured for removably engaging the knob. A collar surrounds at least a portion of the at least one engaging member.
US11135703B2	Device used to temporarily restrain parts and assemblies through manufacturing processes A temporary restraining device is provided that includes a head portion, a central body positioned below the head portion, an upper gap defined between the head portion and the central body, and a base portion positioned below the central body, a lower gap defined between the base portion and the central body. The temporary restraining device maintains a predetermined offset between workpieces disposed within the upper and lower gaps for subsequent manufacturing operations.
US11135698B2	Processing apparatus, processing method, and storage medium Disclosed is a processing apparatus that includes a chamber accommodating a workpiece, a nozzle provided within the chamber, a measuring unit measuring the supply flow rate of the processing fluid supplied to the nozzle, an opening/closing unit performing opening/closing of the flow path of the processing fluid, and a controller. The controller sends an opening/closing operation signal that causes the opening/closing unit to perform an opening/closing operation according to recipe information that indicates processing contents. After sending the opening/closing operation signal to the opening/closing unit according to the recipe information, the controller starts the integration of the supply flow rate based on the measurement result of the measuring unit, monitors the rise of the supply flow rate based on the calculated integrated amount, and when supplying a specific flow rate, monitors the supply flow rate based on a value actually measured by the measuring unit.
US11135689B2	Tool blades and their manufacture There is provided a tool blade, comprising a backing strip particles of abrasive material and a binder layer of binding material which binds the abrasive particles along an edge of the backing strip, wherein the edge of the backing strip is pre-formed with teeth, on which the abrasive particles are bound by the binding material. A profiled cutting portion extends beyond the pre-formed teeth. The pre-formed teeth are shaped as generally triangular waves or are flattened at least partially along an upper edge on which the cutting portion is at least partially disposed. A method of making such a blade is also provided.
US11135682B2	Method for manufacturing a clad sheet product The invention concerns a method for the manufacturing of a clad sheet product comprising a core layer (6) and at least one cladding layer, the method comprising rolling an assembly of a core layer and at least one cladding layer and reducing the thickness to a desired gauge, the core layer being made of an aluminium alloy, the at least one cladding layer comprising a centre section (2) and at least two edge sections (4, 5) positioned at opposite sides of the centre section (2) along the edges of the at least one cladding layer, the centre section being made of a material being an aluminium alloy or a composite material comprising a matrix of aluminium or an aluminium alloy, the edge sections along (4, 5) the edges being made of a material different from the material of the centre section, wherein the edge sections (4, 5) are cut off during or after the rolling. The invention further concerns a cladding plate useful in the method.
US11135680B2	Irradiation devices, machines, and methods for producing three-dimensional components Methods and computer-readable media for producing at least one portion of a layer of a three-dimensional component by irradiating at least one powder layer by at least one high-energy beam, e.g., a laser beam are disclosed. The methods include irradiating the powder layer by the at least one high-energy beam in a processing field, wherein the at least one high-energy beam is moved in a continuous oscillating movement over the powder layer in a first direction to produce a line-shaped irradiation region in which the powder layer is melted, and wherein the line-shaped irradiation region is moved over the powder layer in a second direction that differs from the first to produce the portion of the layer of the three-dimensional component.
US11135679B2	Apparatus for additive manufacturing of a product with a calibration device and method for calibration of an apparatus of this kind An apparatus for layered manufacture of a three-dimensional product includes a build chamber having a window, a build platform within the build chamber, a calibration device that is physically separated from the build chamber, an optical system including a beam source and a scanning apparatus, and a mobile base. The mobile base is configured to position the scanning apparatus at two spaced part positions including a (1) production position and a (2) calibration position. At the production position the scanning apparatus is configured to receive an energy beam from the beam source and to reflect and scan the energy beam through the window and to a build surface over the build platform to create a layer of the three-dimensional product. At the calibration position the scanning apparatus is configured to reflect the energy beam to the calibration device but not through the window.
US11135677B2	Laser welding of component Methods of repair of a component or adding material to a component using laser welding are disclosed. One method may include repairing or adding material to the component by laser irradiating a wire material with a laser in an inert gas in a vicinity of the component. The laser irradiating the wire material includes modulated pulsing the laser through: a warm up phase during which an on-power of the laser is increased over time to a maximum target on-power, a melt and bond phase during which the wire material is melted and during which the on-power is less than the maximum target on-power, and a stress releasing phase during which the on-power of the laser is less than the on-power during the melt and bond phase. The laser irradiated wire material forms a weld material to repair a damaged area or add material to the component.
US11135668B2	Wire electrical discharge machine A wire electrical discharge machine includes a first voltage applying circuit, a second voltage applying circuit, and a switch controller. The first voltage applying circuit includes a first DC power source for applying a positive polarity voltage across an electrode gap, and a first switch for on/off-switching of application of the positive polarity voltage. The second voltage applying circuit includes a second DC power source for applying a reverse polarity voltage to the electrode gap, and a second switch for on/off-switching of application of the reverse polarity voltage. The switch controller controls the first switch and the second switch so that the first switch and the second switch are not turned on simultaneously. The first DC power source and the second DC power source are set up so that the absolute value of the reverse polarity voltage is lower than the absolute value of the positive polarity voltage.
US11135667B2	Machining position correcting device and electrochemical machining device A machining position correcting device is configured to be applied to an electrochemical machining device configured to make an electrolyte flow out of a distal end part of an electrode bar extending along an axis while rotating the electrode bar about the axis to electrochemically machine a material to be machined in a range from the distal end part of the electrode bar. The machining position correcting device includes a position detector configured to detect a rotational position of a feature point of the electrode bar.
US11135661B2	Method for introducing a balancing mark into the compressor wheel of a turbocharger, and turbocharger comprising a compressor wheel which has a balancing mark The invention relates to a method for introducing a balancing mark into the compressor wheel of a turbocharger. According to the method, a milling tool is firstly moved in a first direction in order to introduce a recess into the compressor wheel, and the milling tool located in the recess then runs out in a second direction in order to convert the recess into a pear segment-shaped balancing mark. The invention furthermore relates to a turbocharger which comprises a compressor wheel that has one or more pear segment-shaped balancing marks.
US11135660B2	Cutting processing system and performance test paper for evaluating discharge responsiveness thereof A cutting processing system includes: a spindle mounted with a cutting tool in which a lubrication discharge path is formed along the central axis thereof for rotating the cutting tool; a lance provided inside the spindle in order to supply oil and air to the cutting tool; and a rotary union mounted on the end portion of the spindle for supplying the oil and the air to the lance in a non-mixed state.
US11135653B2	DMLM build release layer and method of use thereof A method for additive manufacturing utilizing a build plate with a release layer is provided. The method includes irradiating a first layer of powder in a powder bed to form a first fused region over a support. The first release layer is provided between the first fused region and the support. The method also includes providing a given layer of powder over the powder bed and irradiating the given layer of powder in the powder bed to form a given fused region. Providing the given layer of powder over the powder bed and irradiating the given layer of powder in the powder bed to form a given fused region are repeated until the object is formed in the powder bed. The object may be formed fusing individual layers with irradiation by laser or ebeam, or by binder jetting. The method further includes separating the object from the support by melting or dissolving the first release layer.
US11135647B2	Iterative learning control for periodic disturbances in twin-roll strip casting with measurement delay A twin roll casting system where the casting rolls have a nip between the casting rolls, each roller having a circumference and a rotational period. The casting roll controller adjusts the nip between the casting rolls in response to control signals. The sensor measures at least one parameter of the cast strip. The ILC controller receives strip measurement signals from the sensor and provides control signals to the casting roll controller. The ILC controller includes an ILC control algorithm to generate the control signals based on the strip measurement signals and a time delay estimate based on circumference, rotational period, and a length of cast strip between the nip and the sensor to compensate for an elapsed time from the cast strip exiting the nip to being measured by the cast strip sensor.
US11135643B2	System and method for manufacturing a part A mould-forming and sacrificial materials are printed into a plurality of layers. The sacrificial material is removed to leave a void defined by a mould structure formed by the mould-forming material. The void is filled with a part-forming material to form the part defined by the shape of the mould structure. The mould structure is removed from the part to free the part from the mould structure. According to a further method, the part-forming material serves the purpose of supporting the mould-forming material and then forming the part. In this case, the part-forming material can be printed together with a mould-forming material as described above and are then heated to a temperature of approximately 700° C. to activate a binder and then heated to a temperature that melts the part-forming material.
US11135642B2	Method for manufacturing ring-rolled product A method for manufacturing a ring-rolled product, which manufactures the ring-rolled product from a ring material, includes a step of rolling the ring material, which has an operation of rolling the ring material from both inner and outer circumferential sides thereof between a mandrel roll and a main roll in a state of rotating the ring material toward one side in a circumferential direction thereof, and induction-heating the ring material by induction heating elements. An induction heating element is disposed on only an outer circumferential side of the ring material or is disposed on each of both the inner and outer circumferential sides in a region immediately before the rolling, or an inclined portion is provided in an outer-peripheral edge portion of a coil in the induction heating element.
US11135640B2	Press-type composite internally and externally threaded portion forming system for manufacture of drum bungs The present invention relates to a press-type composite internally and externally threaded portion forming system. In this case, the press-type composite internally and externally threaded portion forming system includes an expansion-type collet core unit (10) and a contraction-type collet core unit (20) as its principal components so that internally and externally threaded portions are formed by means of a press method in a composite manner in such a way that the expansion forming force of the expansion-type collet core unit (10) and the contraction forming force of the contraction-type collet core unit (20) simultaneously act on the inner and outer circumferential surfaces of a workpiece in opposite directions.
US11135637B2	Method for determining the quality of a joint, and control method for a process of joining a plurality of metal sheets by means of a joining device A method for determining the quality of a joint fabricated in a plurality of metal sheets by a joining device and a control method. The joining device comprises a drive element, and a hold-down device The method may have the following steps: moving the drive element to move the punch and, via at least one first and one second spring, the hold-down device; recording of a force applied by the drive element with a first sensor and of a distance covered by the drive element with a second sensor during a movement of the drive element in a mating direction and opposite thereto as a force/displacement curve; and comparing a linear relief range in the recorded curve with a reference curve.
US11135630B2	Method for producing a densified material from a complex film, production installation and use A method for producing a densified material includes: obtaining a film including at least one first layer of plastic material and one second layer with a composition distinct from the first layer, the first layer having a first melting temperature, or obtaining pieces of such a film; compressing the obtained film or the obtained pieces of film through at least one die of at least one extruder, and obtaining a profile of densified material, the extruder including at least one rotary endless screw pushing the obtained film or pieces of film along a screw axis; and optionally cutting the profile in order to obtain granules of densified material, the compression step being carried out at a maximum compression temperature for the obtained film or pieces of film, the maximum compression temperature being less than the first melting temperature. Also disclosed are installation and use of the densified material.
US11135628B1	Method and apparatus for cleaning an oil and gas well riser assembly with multiple tools simultaneously The present invention relates to a method and apparatus for cleaning an oil and gas well riser section or assembly on location offshore that includes a larger diameter central pipe and a plurality of smaller diameter pipes that are spaced radially away from the central larger diameter pipe. Even more particularly, the present invention relates to an improved method and apparatus for cleaning oil and gas well riser sections wherein a specially configured cap or pair of caps are fitted to the ends of the riser which enable pressure washing cleaning tools (or a camera) to be inserted into and through a selected one of the pipes including either a smaller diameter of the pipes or the central larger diameter pipe and wherein the cap continuously collects spent cleaning fluid and debris, allowing the cleaning process to be done on location without transporting the riser section back onshore.
US11135626B2	Contamination removal apparatus and method A substrate dry cleaning apparatus, a substrate dry cleaning system, and a method of cleaning a substrate are disclosed. The substrate dry cleaning system includes a substrate support and a reactive species generator. The reactive species generator includes a first conduit defining a first flow channel that extends to an outlet of the first conduit, the outlet of the first conduit facing the substrate support, a first electrode, a second electrode facing the first electrode, the first flow channel disposed between the first electrode and the second electrode, a first inert wall disposed between the first electrode and the first flow channel, and a second inert wall disposed between the second electrode and the first flow channel.
US11135621B2	Remote-controlled gasoline cleaner A remote-controlled gasoline cleaner including a main unit, sprayer, and remote control. The main unit includes a controller, start switch device, stop switch device, and gasoline engine start/stop apparatus. The remote control sends a start remote control signal or stop remote control signal to the main unit. The controller controls the start switch device in response to the start remote control signal received, and controls the stop switch device in response to the stop remote control signal received. The start switch device receives a start command of the controller to connect to a power supply circuit of a starter motor in the gasoline engine start/stop apparatus. The starter motor starts a gasoline engine. The stop switch device receives a stop command of the controller to connect to a short circuit of an ignition coil in the gasoline engine start/stop apparatus, thereby blowing out the gasoline engine.
US11135620B2	Autonomous data collection and system control for material recovery facilities Disclosed embodiments include methods and systems for autonomous data collection and system control of a material recovery or recycling facility. In some embodiments, a central control system receives inputs in the form of at least one data stream from each of one or more environmental sensors that reflect the status of a material recovery facility (MRF). The inputs are used to determine the operating status of one or more components of the MRF, and/or composition of a waste stream being processed by the MRF. At least one material handling unit is controlled in response to the inputs to optimize the recovery and/or purity of recyclable or recoverable materials from the waste stream. A service unit or mechanism may also be controlled in response to the inputs indicating that a component of the MRF requires servicing.
US11135617B2	Omniphobically coated fluid channels and related methods The disclosure relates to an omniphobically coated fluid channel including a channel defining an interior channel surface and a flow volume, and a thermoset omniphobic composition as a coating on the interior channel surface. The thermoset omniphobic composition (such as an omniphobic polyurethane or epoxy composition) includes a thermoset polymer with first, second, and third backbone segments. The first, second, and third backbone segments can correspond to urethane or urea reaction products of polyisocyanate(s), amine-functional omniphobic polymer(s), and polyol(s), respectively, for omniphobic polyurethanes. Similarly, the first, second, and third backbone segments can correspond to urea or beta-hydroxy amine reaction products of polyamine(s), isocyanate-functional omniphobic polymer(s), and polyepoxide(s), respectively, for omniphobic epoxies. The thermoset omniphobic composition coating protects the underlying channel material (such as metal material) from corrosion, and it can further reduce the pressure drop of fluid flowing through the channel. The omniphobically coated fluid channel can be used as a component of a heat transfer apparatus.
US11135616B2	Methods of reducing sinuous flow during machining and products formed thereby Methods of machining a body to produce a chip wherein the body is formed of a material and in a state such that the material exhibits sinuous flow during a machining operation. The methods include providing a layer located on a surface of the body, and machining the body by causing engagement between a cutting tool and the body in a contact region below an area of the surface having the coating layer thereon and moving the cutting tool relative to the body to produce the chip having the layer thereon. The layer reduces sinuous flow in the material of the body.
US11135614B1	Golf club head with polymer coated face Methods of applying a polymeric coating to a rear face surface of golf club heads with variable face thickness are disclosed herein. The coating, which preferably comprises polyurea, improves the durability of the face and reduces the hits to failure ratio of the golf club head. The coating improves the performance of the golf club head because it allows for reduction in overall face thickness and easy post-process manipulation to allow for fine-tuning of mass properties after production. The reduction in thickness leads to overall weight reduction, because the polymer is roughly a quarter of the density of titanium or stainless steel, and also reinforces the face, thereby increasing the lifespan of the club.
US11135611B2	System for spraying a wall surface of a building and method therefor The present invention provides an automated system for spraying an wall of a building. The automated system comprises a carrier; a robotic mechanism mounted on the carrier, the robotic mechanism further having an end effector adapted to support a spray nozzle thereon; a visual monitoring system configured to scan structural characteristics and profiles of the wall; a computing device disposed in communication with the visual monitoring system and the robotic mechanism, wherein the computing device is configured to receive the scanned structural characteristics and profile of the wall from the visual monitoring system; and a controller communicably coupled to the computing device, the controller configured to independently control operation of respective ones of the robotic mechanism, and the spray nozzle according to the scanned structural characteristics and profiles of the wall.
US11135608B2	Dispensing device for paste products A dispensing device for paste products, including toothpaste, is provided. The dispensing device includes a container, a pumping diaphragm and a head applied to the container. The head is equipped with a tube and a button for acting on the diaphragm and deforming it for dispensing. The button has a pressure surface for a user's dispensing action. An extension element which, in an active position, is arranged as an extension of the pressure surface of the button, increases a leverage effect.
US11135604B2	Pretreated wastewater spray system A sprayer system for spraying water, onto and for absorption by, a surrounding area, such as used in wastewater treatment. The sprayer system includes a substantially vertical tubular housing extending from a well base to a distal end from which water communicated to the sprayer system is discharged. The tubular housing includes an inner tubular casing slidably supporting a piston assembly which is movable from the well base to the distal end in response to water communicated from a source to the well base. The piston assembly includes a primary check valve that is biased into engagement with an associated seat and includes a spray nozzle located downstream of the main check valve. When water from the source is applied to an effective pressure area on the piston assembly, an upwardly directed force is applied to the piston assembly when water is delivered to the well base. At least one bypass passage communicates bypass water to a region defined between the piston housing and an inside wall of the tubular casing so that warming water is delivered from the well base and flows around the outside surface of the piston assembly, whereby icing, which would otherwise block movement of the piston assembly, is inhibited.
US11135603B2	Cyclone separator apparatus and methods of production There is provided a method of forming a hydrocyclone body including assembling sintered alumina blocks (27) against a form (37), holding the blocks (27) in place with tape (40), locating a hydrocyclone housing over the blocks (27), filling a space between them with settable epoxy/ceramic composite to secure the blocks (27) to the casing, and removing the form (37), resulting in a substantially continuous, wear resistant surface.
US11135602B2	Surface cleaning apparatus, cyclonic air treatment member and surface cleaning apparatus including the same A surface cleaning apparatus comprises an air treatment member having an air treatment chamber. A moveable member is positioned in the air treatment chamber. A driving assembly is drivingly connected to the moveable member wherein an end wall of the air treatment chamber is openable in response to the moveable member being longitudinally translated through at least the portion of the air treatment chamber.
US11135598B2	Apparatus for performing contactless optically-induced dielectrophoresis for separation of circulating tumor cells An apparatus for performing contactless ODEP for separation of CTCs comprises an ODEP device including a first conductive glass, a bio-compatible membrane, and a second conductive glass, the bio-compatible membrane includes a transverse main channel and a longitudinal micro channel perpendicular to the main channel and joining the main channel at a cell separation zone; the first conductive glass includes a first hole and a second hole aligned with two ends of the main channel respectively, and a third hole aligned with one end of the micro channel that is distal to the cell separation zone; a sample receiving member disposed on and aligned with the first hole; an exhaust discharge member disposed on and aligned with the second hole; a target collection member disposed on and aligned with the third hole; and a controller including an optical projection device and an image fetch device.
US11135597B2	Method and system for releasing mineral from synthetic bubbles and beads A synthetic bead for use in mineral separation is described. The synthetic bead has a surface made of a synthetic material such as polymer and the synthetic material is functionalized with molecules having a functional group for attaching mineral particles to the surface in a separation process. The synthetic beads can be placed in flotation cell containing a mixture of water, valuable material and unwanted material or in a pipeline where the mixture is transported from one location to another. The enriched synthetic beads carrying the mineral particles are separated from the unwanted materials in the mixture. The mineral particles are then released from the synthetic beads by means of low pH treatment, ultrasonic agitation, thermal or electromagnetic treatment.
US11135590B2	Cassette and analyzer device A cassette for loading into a bay of an analyzer device, the cassette having a supply chamber for a test tape, an uptake chamber to receive used tape and a test zone between the chambers, where the tape is positioned at a test site for testing purposes, wherein the cassette includes a frame that extends across the test zone on a loading side of the tape, the frame being in a protective position relative to the tape, parallel to and aligned with the tape in the test zone, to protect the tape as the cassette is inserted into the bay of the analyzer device.
US11135589B2	Large microfluidic bioreactor and manufacturing method thereof Large bioreactors based on microfluidic technology, and methods of manufacturing the same, are provided, The big microbioreactor can include a chip or substrate having the microfluidic channels thereon, and the chip can be manufactured by forming a master mold, forming a male mold from a photopolymer plate using replica molding with the Fmold, and transferring features of the male to a polymer material.
US11135585B2	Fluid control device, microparticle measurement device, and fluid control method The present technology is mainly directed to providing a technology that enables smooth setting of sheath liquid. Provided is a fluid control device including at least a support portion that supports a sheath liquid storage unit and a sealed portion that houses the support portion. The support portion is detachable from the sealed portion, and the sealed portion is controlled by pressurization in order to feed sheath liquid stored in the sheath liquid storage unit to a microparticle measurement device.
US11135581B2	Methods and assemblies for molecule recovery According to the present invention there is provided a method of molecule recovery using an assembly which comprises a first flow cell (2) which comprises comprising first ligands (4) which can bind to molecules, and a conduit which can selectively fluidly connect the first flow cell to a collection reservoir (39); the method comprising the steps of (a) flowing a sample fluid along the conduit into the first flow cell (2); (b) flowing a buffer fluid through at least a portion of the conduit, without flowing any of the buffer fluid through the first flow cell (2) so that sample fluid is maintained in the first flow cell (2) but said at least a portion of the conduit is cleaned by the buffer fluid; (c) flowing a buffer fluid through the first flow cell (2) to flush the sample fluid out of the first flow cell (2); (d) lowing a fluid through the first flow cell (2), along the conduit, and into the collection reservoir, so that molecules of the sample fluid which were bound to first ligands (4) and which have become dissociated from the ligand (4) are collected into the fluid which flows through the first flow cell (2) and are brought to the collection reservoir. There is provided a corresponding method for recovering molecules which passively dissociate from first ligands (4), and, a corresponding method for recovering molecules which actively dissociate from first ligands (4). There is further provided corresponding assemblies which can be used to implement the above-mentioned methods.
US11135577B2	Exhaust-gas-purifying metal substrate and exhaust gas purification device using same The invention provides: an exhaust-gas-purifying metal substrate capable of achieving both low pressure loss and high purification performance; and an exhaust gas purification device using the metal substrate. The invention relates to an exhaust-gas-purifying perforated metal substrate in which a corrugated foil and a flat foil are layered and made into a cylindrical shape, wherein: the perforated metal substrate includes from 50/in2 to 800/in2 of cells; the corrugated foil includes a plurality of first holes having an area that is from 2.0 to 50 times the average opening area of the cells; the flat foil includes a plurality of second holes having an area that is from 3.0 to 100 times the average opening area of the cells; and the average value of the area of the first holes in the corrugated foil is smaller than the average value of the area of the second holes in the flat foil.
US11135575B2	Apparatus for regeneration of acidic ionic liquid without addition of a hydrogenation catalyst We provide a process for regenerating a spent acidic ionic liquid, comprising contacting the spent acidic ionic liquid with hydrogen and without an addition of a hydrogenation catalyst; wherein a conjunct polymer content is decreased in the spent acidic ionic liquid to produce regenerated acidic ionic liquid. We also provide a process for making an alkylate gasoline blending component, comprising: a) alkylating a mixture of isoparaffins and olefins using an acidic ionic liquid and an alkyl halide or a hydrogen halide, wherein a conjunct polymer accumulates in a spent acidic ionic liquid; and b) feeding the spent acidic ionic liquid and a hydrogen, and without an addition of a hydrogenation catalyst, to a regeneration reactor operated under selected hydrogenation conditions to produce a regenerated acidic ionic liquid that is used for the alkylating, wherein the conjunct polymer in the regenerated acidic ionic liquid is decreased by at least 50 wt %.
US11135571B2	SCR catalyst The present invention relates to a catalyst comprising at least one oxide of vanadium, at least one oxide of tungsten, at least one oxide of cerium, at least one oxide of titanium and at least one oxide of antimony, and an exhaust system containing said oxides.
US11135567B1	Microcrystalline cellulose particle supported sol-gel sorbents and methods of manufacturing the same Solid phase extraction (SPE) sorbents and liquid chromatography (LC) stationary phases are provided, as well as methods of fabricating the same. The SPE sorbents and LC stationary phases can use microcrystalline cellulose particles as the substrate and sol-gel sorbent coating technology as the polymer/sorbent immobilization technology. The SPE sorbents and LC stationary phases are stable in a pH range of 1-13 and at a temperature of up to 350° C.
US11135566B2	Porous fiber and adsorption column The present invention provides: a porous fiber that exhibits both improved adsorption capacity, and suppressed exposure and detachment of particulates; an adsorption column filled with said porous fiber; and a blood purification system in which an adsorption column is connected to a water removal column. The porous fiber according to the present invention has a three-dimensional pore structure formed by a solid fiber, and satisfies all of the following conditions. (1) The porous fiber has particulates having a diameter of not more than 200 μm, and the percentage of area occupied by said particulates having a diameter of not more than 200 μm in a horizontal cross section of the three-dimensional pore structure is at least 3.0%. (2) The porous fiber does not contain said particulates having a diameter of not more than 200 μm in the region within 1.0 μm in the depth direction from the outermost surface.
US11135564B2	Porous polymer compositions for the synthesis of monolithic bimodal microporous/macroporous carbon compositions useful for selective CO2 sequestration The present invention discloses novel porous polymeric compositions comprising random copolymers of amides, imides, ureas, and carbamic-anhydrides, useful for the synthesis of monolithic bimodal microporous/macroporous carbon aerogels. It also discloses methods for producing said microporous/macroporous carbon aerogels by the reaction of a polyisocyanate compound and a polycarboxylic acid compound, followed by pyrolytic carbonization, and by reactive etching with CO2 at elevated temperatures. Also disclosed are methods for using the microporous/macroporous carbon aerogels in the selective capture and sequestration of carbon dioxide.
US11135563B1	Method for making a water treatment adsorbent filter A method of removing an organic pollutant from water by contacting the water with a ball milled and sonicated oil fly ash powder to adsorb the organic pollutant onto the ball milled and sonicated oil fly ash powder. A method of producing a ball milled and sonicated oil fly ash powder involving ball milling oil fly ash to provide ball milled oil fly ash particles with an average particle size of less than 1 μm and sonicating the ball milled oil fly ash particles in an aqueous medium to form the ball milled and sonicated oil fly ash powder. A method of improving recovery of valuable metals/elements from oil fly ash.
US11135562B2	Magnetic adsorbent for removing arsenic and antimony by means of adsorption-superconducting magnetic separation and preparation method therefor A magnetic adsorbent, preparation method therefor and application thereof. The magnetic adsorbent is made by loading a weakly material with high adsorption capacity, an iron-based gel, onto a strongly magnetic ferrite material with low adsorption capacity by means of in-situ reaction. The magnetic adsorbent is used for removing heavy metal pollutants and phosphate pollutants from water.
US11135560B1	Aqueous leaching solutions and methods of leaching at least one interstitial constituent from a polycrystalline diamond body using the same In an embodiment, a polycrystalline diamond table includes a plurality of bonded diamond grains and a plurality of interstitial regions defined by the plurality of bonded diamond grains. The polycrystalline diamond table may be at least partially leached such that at least a portion of at least one interstitial constituent has been removed from at least a portion of the plurality of interstitial regions by exposure to a leaching agent. The leaching agent may include a mixture having a ratio of weight % hydrofluoric acid to weight % nitric acid of about 1.0 to about 2.4, and water in a concentration of about 50 weight % to about 85 weight %. Various other materials, articles, and methods are also disclosed.
US11135558B2	Oil-water-vacuum-mixed fuel production apparatus The present invention relates to an apparatus for producing a fuel made by mixing water with oil in a vacuum state. The apparatus includes: a vacuum tank adapted to seal an internal space thereof to allow the internal space to be maintained to a vacuum state; a vacuum pump located on one side of the vacuum tank to suck the air from the interior of the vacuum tank, so that the vacuum tank is kept in the vacuum state; a stirring vessel located inside the vacuum tank in such a manner as to communicate with the vacuum tank through a bypass pipe, the water and oil being supplied thereto; and stirrers rotating by the drive of motors to stirringly mix the water with the oil.
US11135547B1	Air cooled condensing heat exchanger system with acid condensate neutralizer An air-cooled condensing heat exchanger system (“ACHX”) installed in a fossil power plant flue gas treatment system recovers water and low temperature waste heat from boiler flue gas for advanced coal fired power plant applications. More particularly, the ACHX system recovers water from combustion flue gas by phase change. To recover water from flue gas, the ACHX system uses ambient air from an air intake installed on the stack to cool down the flue gas in the ACHX.
US11135546B2	Graphene based filter Two-dimensional material based filters, their method of manufacture, and their use are disclosed. The filters may include at least one active layer disposed on a porous substrate. The at least one active layer may include intrinsic and/or intentional formed pores. In some embodiments, the flow resistance of the porous substrate may be selected to limit flow through defects and intrinsic pores in the at least one active layer.
US11135541B2	Folding air filter assembly and apparatus This document presents an apparatus for a flexible air filter media that can be configured for shipping and storage having one or more flexible inserts mounted to the filter media along one or more portions of the accordion folds of the air filter material. The current invention permits the air filter apparatus to fold along both X and Y axes, create a tri-fold, and bend in a manner that provides for a much smaller volume for shipping purposes. The invention also permits attaching the flexible material to the center of the filter media and also inserts which allow sections of the air filter media to be nested one into another to reduce both shipping and storage volume.
US11135533B2	Oil filter An oil filter assembly is disclosed for a machine, such as an internal combustion engine, that has an oil output port and an oil input port. A mounting plate may be fixed with an outer enclosure and may be adapted for securing to the machine. The mounting plate may be further adapted to conduct oil from the machine into a peripheral portion of the outer enclosure, and then returning oil from a central portion of the outer enclosure back to the machine. Oil may pass from the peripheral portion to the central portion through a primary filter having a first porosity. A pressure-actuated valve may be fixed fluidly between the peripheral portion and central portion of the outer enclosure. Oil may pass through the pressure-actuated valve only when an oil pressure differential between the peripheral portion and the central portion of the outer enclosure exceeds a predetermined threshold pressure. A secondary filter may have a second porosity greater than the first porosity, and may be fixed fluidly between the pressure-actuated valve and the central portion of the outer enclosure.
US11135525B2	Accordion fold play structure with easy-up assembly device Embodiments may relate to a foldable play structure which may be easily assembled and which may be form of four or more panels each connected to another to provide an accordion fold structure; corner hinges comprising a first hinge portion attached to one panel of the at least four panels; a second hinge portion attached to another panel of the at least four panels; and a fastener configured to be retained within either the first portion or the second portion; and mid-wall hinge(s) attached to two of the panels and located between the corner hinges. Typically, in a first configuration, the panels of the accordion fold structure are folded to be stacked in substantially parallel planes, and in a second configuration, the panels are unfolded forming a play structure. The retained fastener may be used to secure the corner panels together.
US11135519B2	Storage medium, information processing apparatus, information processing system and information processing method A non-limiting example game system includes a processor incorporated within a main body apparatus, and the processor creates, based on operation inputs of a player, a game stage by selecting components corresponding to a virtual room and by arranging panels corresponding to the components on a grid-shaped arrangement area. In the virtual room, a passage, a stairs, a door with lock blocking the passage and a treasure chest are arranged. A key for releasing the door with lock is contained in the treasure chest. The player creates the game stage by connecting all of the passages and the stairs from a start room that a game is started to a room where a boss enemy object is arranged and by taking arrangement of the doors with lock and the treasure chests containing the key into consideration.
US11135517B2	Computer-readable non-transitory storage medium having image processing program stored therein for displaying game with curved-surface game field, image processing system, image processing apparatus, and image processing method A plurality of terrain/background objects each including at least a part of a cylindrical curved surface are arranged within a virtual space, and an operation object to be operated on the basis of an operation input on an operation device is controlled within the virtual space. Furthermore, the plurality of terrain/background objects are rotated about rotation center axes on the basis of a movement instruction input to the operation device such that a relative positional relationship between each of the plurality of terrain/background objects and the operation object is changed. Then, an image of the virtual space to be displayed on a display device is generated using a virtual camera.
US11135514B2	Data processing method and apparatus, and storage medium for concurrently executing event characters on a game client A data processing method includes obtaining sample data of event execution of a game client, and performing preprocessing on the sample data to obtain a plurality of layers of data combinations. Each layer of the plurality of layers of data combinations corresponds to a target event object in a same target event, different layers correspond to different target event objects in the target event, and the target event objects are event objects on the game client to be executed concurrently. The method also includes performing processing on each layer of data combinations according to a preset processing algorithm, to obtain a processing result of each layer of data combinations, and performing consolidation processing on the processing result to obtain a target instruction. The target instruction is used for instructing the game client to concurrently execute the different target event objects corresponding to the different layers of data combinations.
US11135509B2	Systems and methods of directing remote player interactions A method of providing gameplay experiences for users includes communicating with a plurality of game clients via a network, where each of the game clients is running a game application. The method further includes identifying a plurality of users of the game applications on the game clients, assigning each of the users to a team in a game instance, and assigning the users to one of a plurality of squads on the team. The method continues by initiating an activity mode in the game instance, where the activity mode includes assigning a different activity to each of the squads and tracking progress toward completion of each activity by users of the assigned squad. Upon satisfaction of the completion criteria of the activity mode, the method ends the activity mode and initiates an objective mode. The objective mode includes assigning an objective to the team.
US11135508B2	Information processing system, storage medium storing information processing program, information processing method and information processing apparatus An example of an information processing system includes a vibrator. The information processing system is configured to store a frequency model function representing a model of vibration frequency transition, wherein the frequency model function includes, as variables thereof, a frequency variable representing a frequency for a period in the model and a period variable for that period. The information processing system is configured to determine a value of the frequency variable and a value of the period variable. The information processing system is configured to generate vibration information representing a vibration pattern that is defined by a frequency transition obtained by applying the value of the frequency variable and the value of the period variable to the frequency model function. The information processing system is configured to control vibration of the vibrator based on the vibration information.
US11135499B2	Convertible fitness bag A fitness apparatus is described which can be configured to operate both as a bag for carrying and storing exercise equipment and as a fixed anchor to which the exercise equipment can be connected. When operated as a bag, the apparatus can be filled with accessories and attachments that are utilized while performing exercises. These accessories can include, for example, Yoga Ropes, Pilates Springs, or Pulley Ropes. The fitness apparatus is converted to a fixed anchor by unzipping a zipper and turning the bag inside out, thereby exposing straps which are sewn onto the inside of the bag, and wrapping the straps around a door to provide fixed anchor points to which the accessories can be affixed. The straps which are wrapped around the door can be connected to one another on the opposite side of the door from the bag, thereby securing the apparatus to the door.
US11135486B2	Multi-component golf club head Embodiments of golf club heads with enclosed weight members are described herein. In many embodiments, the club head comprises a body having a front end, a back end, a heel end, a toe end, a top rail, and a sole; the body further including a front body defining the front end; a rear body coupled to the front body, wherein the rear body is formed of a second material having a second density; a plurality of weight receptacles defined in one or both of the front body and the rear body and one or more weight members received into the weight receptacles, the one or more weight members being formed of a third material having a third density; and wherein the one or more weight members are fully enclosed between the front body and the rear body.
US11135473B2	Media holder for exercise machine A media holder for an exercise machine in accordance with some examples herein may include a first portion, a second portion movable relative to the first portion; and a size adjustment mechanism movably connecting the second portion to the first portion to enable resizing of a media holding region independent of whether a media item is present in the media holding region. The size adjustment mechanism may include an arm pivotally coupled to the second portion and configured to selectively engage the first portion in a plurality of positions.
US11135470B2	Exercise apparatus A piece of exercise equipment particularly for improved strength training exercises. More particularly, the invention relates to equipment that allows the user to vary tension when performing different exercises. The present invention is specifically designed for improved exercise through the variability of a tension component for use in such exercises as the plank exercise, sit-ups, push-ups and supine pull-ups that includes a core support, a guide arm, a head support, and a foot support that work in conjunction to most optimally support the user. The core support, the head support and the foot support are all connected, supported, and elevated from the floor by a central support system.
US11135468B2	Weight bar stopper A exercise equipment includes a weight bar, a plurality of weight plates slidably coupled at two ends portions of the weight bar from two free ends thereof respectively, and a weight bar stopper built-in at each of the end portions of the weight bar to increase a peripheral size of the weight bar at the end portion thereof to block the weight plate being slid out of the free end of the weight bar. When the weight bar stopper is actuated to adjust the peripheral size of the weight bar back to its original size, the weight plate is allowed to be slid in and out the end portion of the weight bar.
US11135462B2	Trampoline A trampoline has a side frame supported by support legs, multiple fiberglass guardrail poles joined to the side frame or the support legs, and a guardrail netting held open by the guardrail poles. Each guardrail pole includes two fiberglass rods joined together by a connector that includes two nested securing tubes, where two respective ends of the two fiberglass rods are inserted in the internal securing tube. The external securing tube is secured outside of the internal securing tube. The guardrail netting has multiple securing fabric sleeves stitched to its top end. Each sleeve has a first part with a sealed top and a width matching that of a wider top section of the fiberglass guardrail pole, and a second part connected to the first part with a width matching that of the fiberglass guardrail pole, where the second part has a gap in the middle.
US11135459B1	Dual filtration COVID-19 mask A mask includes: an intake valve panel comprising one or more intake valves, the intake valve panel further comprising an intake filter configured to filter the user's intake breath, the intake valve panel positioned in a center of the mask; one or more exhaust tubes, at least one of the one or more exhaust tubes comprising at least one of the exhaust valves, at least one of the exhaust tubes configured to conduct the user's exhale breath through the at least one of the exhaust valves and then out of the mask, at least one exhaust tube holding the at least one exhaust valve tightly while allowing the at least one exhaust valve to open and close freely; and a soft foam lining configured to tightly hold the mask against the user's face.
US11135454B2	Histotripsy therapy systems and methods for the treatment of brain tissue A histotripsy therapy system configured for the treatment of brain tissue is provided, which may include any number of features. In one embodiment, the system includes an ultrasound therapy transducer, a drainage catheter, and a plurality of piezoelectric sensors disposed in the drainage catheter. The ultrasound therapy is configured to transmit ultrasound pulses into the brain to generate cavitation that liquefies a target tissue in the brain. The drainage catheter is configured to detect the ultrasound pulses. An aberration correction algorithm can be executed by the system based on the ultrasound pulses measured by the drainage catheter to automatically correct for an aberration effect caused by the ultrasound pulses passing through a skullcap of the patient.
US11135448B2	Streamlined, guided on-couch adaptive workflow Systems and methods for implementing an adaptive therapy workflow that minimizes time needed to create a session patient model, select an appropriate plan for the treatment session, and treat the patient.
US11135445B2	Antimicrobial photodynamic inactivation procedure and system A problem of incomplete inhibition of harmful cells/bacteria and short duration of time, after the photodynamic treatment, during which such cells may re-grow, is solved by exposing the target bacteria with a multi-component photosensitizer material formed by adding a predetermined potentiating chemical to a conventional single-component photosensitizer at the target, prior to irradiating the target with light. The multi-component photosensitizer is effectuated by forming a mix of the two chemical compositions or by sequential exposure of the bacteria to a single-component photosensitizer and the potentiating chemical of choice.
US11135443B2	System for treatment by photodynamic therapy of a cavity of a patient's body and method for preparation of such system System (1) for treatment by photodynamic therapy comprising an illuminating member (6) which comprises: —a core (35) carrying a light emitting surface (37), and —a hollow sheath (10) adapted to receive the core (35) with the light emitting surface (37) arranged within a balloon (11), the balloon (11) comprising a wall (12) which has an inner surface delimiting an internal space, and an outer surface, the wall (12) being flexible, wherein the internal space of the balloon (11) has a variable capacity, the wall (12) of the balloon (11) being elastically extendible and the balloon (11) presenting a plurality of inflated states in each of which the internal space is filled with a volume of light diffusing solution, and wherein the system further comprises a support provided with a transfer function relating the volume of light diffusing solution of each inflated state with at least one of a corresponding distribution of light power at the outer surface of the wall (12) of the balloon (11) and a corresponding time of illumination for providing a determined dose of light energy.
US11135439B2	Implantable pulse generator for providing a neurostimulation therapy using complex impedance measurements and methods of operation Embodiments are directed to an implantable medical device comprising therapeutic stimulation circuitry for controlling delivery of a medical therapy to a patient, the therapeutic stimulation circuitry having at least one lead having electrodes for delivering the medical therapy. The implantable medical device further comprises measurement circuitry for determining characteristics of the at least one lead, a processor for controlling the IMD according to executable code, and memory for storing data and executable code, wherein the executable code comprises instructions for causing the processor to receive a plurality of voltage measurements associated with the electrodes, and calculate values for an impedance model of the electrode/tissue interface.
US11135436B2	System, device, and method for generating stimulation waveform having a paresthesia-inducing low-frequency component and a spread-spectrum high-frequency component A pulse generator includes charging circuitry configured to provide electrical power to the pulse generator. The pulse generator includes communication circuitry configured to conduct wireless telecommunications with external programming devices. The telecommunications contain programming instructions sent from the external programming devices. The pulse generator includes stimulation circuitry configured to generate electrical pulses based on the programming instructions. The electrical pulses include a first component that is paresthesia-inducing and a second component that is non-paresthesia-inducing.
US11135434B2	Systems and methods for improved damage protection during electrostatic discharge and cardiac defibrillation, and for substantially improved stimulation interference mitigation in implantable pulse generators The present disclosure provides systems and methods for protection circuitry for an implantable pulse generator (IPG) of a neurostimulation system. The protection circuitry is coupled to an IPG ground, a plurality of electrodes, and an IPG case, and operable to protect IPG stimulation and sensing circuitry from damage during electrostatic discharge and cardiac defibrillation, and to mitigate unintended stimulation during electromagnetic interference. The protection circuitry includes an IPG ground connection, a plurality of protection Zener diodes, wherein one of the protection Zener diodes is electrically coupled between the IPG case and a float Zener diode, and wherein the remaining protection Zener diodes are electrically coupled between the plurality of electrodes and the float Zener diode, and the float Zener diode electrically coupled between the plurality of protection Zener diodes and the IPG ground.
US11135433B2	Systems and methods for ranking and selection of pacing vectors Approaches to rank potential left ventricular (LV) pacing vectors are described. Early elimination tests are performed to determine the viability of LV cathode electrodes. Some LV cathodes are eliminated from further testing based on the early elimination tests. LV cathodes identified as viable cathodes are tested further. Viable LV cathode electrodes are tested for hemodynamic efficacy. Cardiac capture and phrenic nerve activation thresholds are then measured for potential LV pacing vectors comprising a viable LV cathode electrode and an anode electrode. The potential LV pacing vectors are ranked based on one or more of the hemodynamic efficacy of the LV cathodes, the cardiac capture thresholds, and the phrenic nerve activation thresholds.
US11135431B2	Implantable pulse generator with multiple stimulation engines An implantable medical device (IMD) includes multiple stimulation engines for independently stimulating respective electrode sets of a lead system while avoiding collisions and/or channel contention during stimulation delivery. A first voltage multiplier is configured to generate an adjustable target voltage having sufficient headroom at an output node that is commonly coupled to anodic nodes of respective stimulation engines. Each stimulation engine includes a secondary voltage multiplier to drive the respective anode and a current regulator powered by a floating voltage supply, wherein the current regulator is coupled to a cathodic node and configured to control how much stimulation current is pulled from the patient tissue.
US11135429B2	Neural oscillatory signal source location detection Techniques are described to determine a location of at least one oscillatory signal source in a patient. Processing circuitry may determine expected electrical signal levels based on a hypothetical location of the at least one oscillatory signal source. Processing circuitry may determine the electrical signal levels and determine an error value based on the expected electrical signal levels and the determined electrical signal levels. Processing circuitry may adjust the hypothetical location of the at least one oscillatory signal source until the error value is less than or equal to a threshold value, including the example where the error value is minimized.
US11135425B2	Device for suppressing inflammation and hyperimmunity, and method for suppressing inflammation and hyperimmunity Provided is a new means for suppressing inflammation or suppressing inflammatory cytokine production. Provided is a device in which a weak pulse current is passed through a living body or living tissue to suppress inflammation in the living body or the living tissue. This device is provided with a power supply means, and a current control means for receiving a supply of power to intermittently apply a direct current at prescribed intervals, and is configured such that the current control means includes a pulse width modulation control means, and the pulse width modulation control means generates a pulse wave that is a rectangular wave, and in which the time indicating a peak value for rising in one cycle of the pulse wave (“pulse duration”) is at least 0.1 millisecond, the peak value is 1.0-20 V, inclusive, and the duty ratio of the pulse wave is at least 5.5%.
US11135423B2	Medical lead with segmented electrodes A medical lead system includes a lead body, a plurality of electrical conductors, and a plurality of electrodes. The lead body may include a distal end and a proximal end defining a longitudinal axis of the lead body. The plurality of electrical conductors extending about the longitudinal axis of the lead body. The plurality of electrodes is positioned around an outer perimeter of the lead body. An inner surface of each of the plurality of electrodes defines an inner perimeter. Each respective electrode of the plurality of electrodes is electrically coupled to a respective electrical conductor of the plurality of electrical conductors. Each electrode of the plurality of electrodes includes at least one electrode locking feature extending into the lead body from the inner perimeter.
US11135419B1	Single chamber intracardiac balloon pump A method, apparatus and computer system product for improving cardiac output from the heart is presented. A balloon is placed within a chamber of a heart wherein the balloon encloses a mechanical expansion device and air. During a first time epoch in which the heart chamber is volumetrically contracting (during emptying), a mechanical expansion device causes the balloon to increase in size, which improves ejection fraction. During a second time epoch in which the heart chamber is volumetrically expanding (during filling), the mechanical expansion device causes the balloon to decrease in size, which improves filling.
US11135416B2	Systems, methods, and components for transferring medical fluids An example of a method of enabling medical fluid transfer between a source container and a destination container can comprise the steps of providing a closed-system fluid transfer module comprising a first closeable, resealable medical connector and a second closeable, resealable medical connector, a multidirectional fluid control valve with a driving interface configured to interface with an electromechanical driver of an electronic medical fluid transfer device, and an intermediate container or an intermediate pumping region; and instructing a user to couple the closed-system fluid transfer module to the electronic medical fluid transfer device.
US11135415B2	Microneedle using biodegradable metal A microneedle using a biodegradable metal is represented by Chemical Formula 1 and is absorbed and degraded after subcutaneous or epithelial insertion to thus release metal ions and degradation products into the body. In Chemical Formula 1, a, b, and c represent wt % of respective ingredients, a+b+c=100 wt %, a or b has the highest value in the range of 0≤a≤100, 0≤b≤100, and 0≤c≤10, and X is one or more selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P.
US11135412B2	Skin therapy systems The disclosed invention provides a skin therapy system for skin conditioning or treatment of a body part. The skin therapy system includes a body part shaped encaser including a first and second film substrate and an encaser liner disposed between the first and second film substrates. An outer peripheral edge of the encaser liner is sealed between outer peripheral edges of the first and second film substrates to create a hermetic seal forming a first fillable space between the first film substrate and a first layer of the encaser liner, a second fillable space between the second film substrate and a second layer of the encaser liner, and an internal volume defined by the first and second layers of the encaser liner and disposed between the first and second fillable spaces. The skin therapy system further includes a therapeutic composition contained within the first and second fillable spaces.
US11135409B2	Balloon wrapping apparatus and balloon wrapping method A balloon wrapping apparatus for folding a balloon at a distal portion of an elongated shaft includes: a pleating section that forms the balloon with pleats; a folding section that folds the pleats formed in the balloon, along a circumferential direction; and a support base that supports the shaft and can be moved toward and away from the pleating section. The pleating section includes an insertion hole through which the balloon can be inserted, and a back surface hole provided in a back surface on the side opposite to the side on which the insertion hole is provided. The pleating section includes an assisting shaft which can be inserted into the back surface hole from the rear surface side, and an interlock portion interlocking the assisting shaft with the support base. The assisting shaft is formed with a cavity portion.
US11135407B2	Expandable intubation assemblies Expandable intubation assemblies and methods for using and making the same are provided.
US11135401B2	Urinary catheter support A urinary catheter support configured to support an indwelling urinary catheter such that the urinary catheter is secured relative to the penis of a male patient includes a flexible main body having an interior size and configured to receive and accommodate the penis of the male patient. A catheter support is located at a front end of the main body and is configured to support a catheter adjacent a longitudinal axis of the main body. A slot extends along the longitudinal axis through the main body and the catheter support. A strap includes first and second end segments and a middle segment between the first and second end segments. The first and second end segments respectively extend through first and second openings in the main body, and the middle segment extends through an interior of the main body.
US11135392B2	Mechanical ventilator A ventilator includes a bidirectional breath detection airline and a flow outlet airline. The flow outlet airline includes an airline outlet. The flow outlet airline is configured to be connected to an invasive ventilator circuit or a noninvasive ventilator circuit. The breath detection airline includes airline inlet. The airline inlet is separated from the airline outlet of the flow outlet airline. The ventilator further includes a pressure sensor in direct fluid communication with the breath detection airline. The pressure sensor is configured to measure breathing pressure from the user and generate sensor data indicative of breathing by the user. The ventilator further includes a controller in electronic communication with the pressure sensor. The controller is programmed to detect the breathing by the user based on the sensor data received from the pressure sensor.
US11135391B2	Breathing tube Condensation or “rain-out” is a problem in breathing circuits and especially neonatal breathing circuits. The subject patent provides an improved breathing tube component for managing rain-out particularly in neonatal applications. In particular the breathing tube has a smooth inner bore, and an outer insulating layer containing stagnant gas and a heater wire.
US11135388B2	Patient interface, system and method This invention relates to a patient interface, a system and/or method for providing a dedicated or sole inspiratory line or conduit for provision of inspiratory gases to a patient, and a dedicated or sole expiratory line or conduit for provision of expiratory 5 gases to a downstream device, where the inspiratory line or conduit is sealing engageable with the first of a user's nares and the expiratory line or conduit is sealing engageable with the second of the user's nares.
US11135384B2	Method, apparatus and system for automatically controlling inspired oxygen delivery Provided herein is a method for automatically controlling inspired oxygen delivery, including: receiving signals representing a plurality of input oxygen saturation (SpO2) values for a patient; generating control values based on the input SpO2 values and a target SpO2 value; and generating output inspired oxygen concentration (FiO2) values based on the control values and reference inspired oxygen concentration (rFiO2) values; wherein the control values include: immediate control values, generated based on the input SpO2 values, the target SpO2 value, and an immediate gain coefficient; accumulation control values, generated based on the input SpO2 values, the target SpO2 value, and an accumulation gain coefficient; and predictive control values, generated based on the input SpO2 values, the target SpO2 value, and a predictive gain coefficient; wherein the immediate gain coefficient is determined based on the rFiO2 value; and wherein a non-linear compensation weighting is applied to the accumulation control value based on a predetermined non-linear relationship between partial pressure of arterial oxygen (PaO2) and SpO2.
US11135383B2	Resuscitation device with onboard processor A resuscitator has a patient airway interface device, a bag, a fluid passage coupled between the bag and patient airway interface device, and a sensor module. The patient airway interface device may be a mask or an endotracheal tube. The sensor module can have a display, at least one sensor coupled to the flow passage and configured to provide a measurement of at least one parameter, and a processor coupled to the display and the at least one sensor. The processor is configured to receive the measurement from the sensor and provide information on the display based on the received measurement. The information may include a current breath rate, a pressure-vs-time curve, and guidance to the user to assist in achieving a target breath rate.
US11135382B2	Medical device and process for alarm organization A medical device is provided with an alarm organization. A process for alarm organization of a medical device is also provided. Based on pressure measured values and flow measured values and with a comparison criterion, it is determined whether an elevation of an airway pressure of an anesthesia device or of a ventilator is caused by a coughing event. A visual and/or acoustic output of a warning or alarm is adapted, indicating the elevated airway pressure PAW_High.
US11135380B2	Device for cell spraying The invention provides a description of a method and a device suitable for producing a cell suspension spray with living cells, and the produced cell preparation, suitable for grafting to a patient. In contrast to other methods, the spraying is performed through a disposable needle which is inserted into a disposable air tube; which provides a cell distribution avoiding spray nozzles. Small suspension droplets are provided instead of cell nebulization. By using medical grade sterile Luer-lock disposables from medical routine praxis, biocompatibility and easy application is addressed. In applying the method and/or in using the device, cells suitable for grafting to a patient are dispersed in a solution and sprayed with the device for distribution over the recipient graft site.
US11135376B2	Dosing mechanism for multi-shot injection device comprising flexible ratchet element The disclosure provides a dose controlled multi-shot injection device comprising a housing and a dose setting mechanism, wherein the dose setting mechanism includes a drive spring, a rotatable dose setting handle adapted to set a dose of medicament, thereby biasing the drive spring, and a ratchet mechanism for maintaining the drive spring in a biased state against a spring force at a set dose. The ratchet mechanism includes a fixed ratchet element coupled to the housing and having a circumferential teething, a movable flexible ratchet element provided with at least two teethed portions configured to engage the circumferential teething at least pairwise at any one of a plurality of engaging positions, which respectively represent a set dose, and a rotational element coupled to the dose setting handle configured to translate torque from the dose setting handle into a number of forces radially acting on the flexible ratchet element resulting in an elastic deformation of the flexible ratchet element, thereby releasing the engagement between the teethed portion and the circumferential teething.
US11135375B2	Volume monitoring systems A method of determining an amount of medium injected into a patient includes receiving an injection signal from a sensor associated with an injection syringe. A diversion signal is received from a sensor associated with a diversion reservoir. The amount of medium injected is determined based at least in part on the injection signal and the diversion signal.
US11135374B2	Medicament delivery and simulation system with a removable disposable container for medicament delivery and training Embodiments of the invention include a medicament device configured to provide stepwise instructions for using the device to a user in a particular sequence is provided. The device includes a device housing configured to receive a container, the housing including a control interface, the control interface including at least one responsive member reactive to a user input, an actuation mechanism configured to interact with the container, a signal output component associated with the device housing, and circuitry associated with the device housing configured to control a provision of the stepwise instructions to the user in the particular sequence. The container includes a first housing for containing a medicament, a second housing, and an injection member, wherein the first and second housings are movable relative to one another. The container further includes an injection member which is retractable within the second housing to prevent an unintentional contact with the injection member.
US11135372B2	Medical plunger pump and cavity structure thereof A medical plunger pump and a chamber structure thereof. The chamber structure includes a barrel, where the barrel is provided with at least one cylindrical chamber which includes a piston working section in which a piston is able to reciprocate and a joint section where the piston is connected to a push rod. The joint section includes a first arc section that protrudes from the piston working section, where a first end of the first arc section is smoothly connected to a side wall of the piston working section, and a second end of the first arc section is bent and extendable along an axis of the piston working section. The medical plunger pump includes the above-mentioned chamber structure.
US11135368B2	Estimation of future insulin sensitivity distributions A method and device for using insulin sensitivity values to estimate the distribution of future insulin sensitivity values for a given patient based on dimensional relationships between current, prior and delta insulin sensitivity values, and observed future insulin sensitivity values for similar patients or subjects, or based on an individual patient or subject's historical values.
US11135365B2	Ambulatory medicament device with security override passcode An ambulatory medicament device can generate a dose control signal for delivery of medicament to a subject and secure at least some functionality of a user interface of the ambulatory medicament device. The ambulatory medicament device can have a locked state that restricts modification of at least one control parameter. The ambulatory medicament device can have an unlocked state that allows modification of at least one control parameter. The ambulatory medicament device can accept a user input of a security code that is validated against a passcode to enter from the locked state to the unlocked state.
US11135363B2	Ambulatory medicament device alarm system Systems and methods relate to an ambulatory medicament device that can generate a dose control signal to cause a medicament pump to infuse medicament into a subject. The system can analyze status to determine whether an alarm condition for the ambulatory medicament device or for a subject is already present in a list of pending alarm conditions. If the alarm is not present, the system can determine a severity level of the alarm condition from among a plurality of severity levels and annunciate the alarm condition using one or more annunciation patterns selected based on the severity level of the alarm condition for the medicament device or for the subject. The system may maintain an indication of the alarm condition on the list of pending alarm conditions until the alarm condition is resolved.
US11135362B2	Infusion pump systems and methods Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.
US11135360B1	Concurrent infusion with common line auto flush An infusion pump system and method provide concurrent infusion with common line auto flush. The infusion pump system has a first reservoir, a second reservoir, a junction, a mixing chamber, a common line having one end in fluid connection with the mixing chamber and having a terminal fluid delivery end, and an infusion pump. The method includes infusing the first fluid at a first rate along a first flow path; determining a common line flush volume value for the common line; switching to a concurrent infusion mode to drive a combination of the first fluid and the second fluid at the first rate along a second flow path including the common line; monitoring a volume of the combination of the first and second fluids driven at the first rate; and driving the combination of the first and second fluids at a combined rate along the second flow path when the monitored volume is equal to or greater than the common line flush volume value.
US11135354B2	Fluid delivery pump A pump controllably moves a small quantity of fluid from a fluid chamber to an outlet port with a small inexpensive actuator powered for a very short amount of time, thereby optimizing cost, size, and battery efficiency. Multiple pumps can be housed in a single enclosure, allowing multiple drugs to each be injected through a single cannula or needle.
US11135352B2	End effector including a gradually releasable medical adjunct An end effector for use with a surgical system is disclosed. The end effector comprises a medical adjunct gradually releasable from the end effector, a pair of jaws configured to grasp tissue therebetween, a firing member, and a cutting member configured to cut the tissue and gradually release the medical adjunct from the end effector in an overlapping timeframe, based on advancement of the firing member.
US11135351B2	Systems and methods for applying reduced pressure therapy Embodiments disclosed herein are directed to the treatment of wounds using negative pressure. Some embodiments disclosed herein provide for a hydrophilic drainage layer, which may be suitable for use in abdominal wound sites, and which may be sized in a dimensionally-independent manner. Additional embodiments provide for an organ protection layer, as well as a system for the treatment of abdominal wounds.
US11135350B2	Catheter anchor drain The disclosure relates to a system of circumferentially (preferably helically) arranging indicia on the elongate body of a medical device such as a catheter. The disclosure also relates to an anchor drain for securing a surgical drain to a fluid collection device. The anchor drain resists disconnection of the surgical drain from the fluid collection device and also resists occlusion of the conduit connecting the surgical drain and the fluid collection device, even when a suture is tied about a portion of the anchor drain inserted within the surgical drain, and resists unintentional withdrawal of the surgical drain from the body or a body cavity.
US11135347B2	Dialysis device and method of dialysis The present disclosure relates to dialysis devices. In some embodiments, a dialysis device may include a disposable housing having a storage chamber in fluid communication with a dialysate flow path. Also included may be a controller, an interface capable of operably coupling the controller and the disposable housing, a fluid displacement structure, a pump configured to actuate a deformable diaphragm, and a pressure sensor to trigger the reversal of the pump. The flow path may be fluidly sealed from the controller and the interface.
US11135344B2	Dialysis system for ultra-low total chlorine detection in at least partially purified water A dialysis system for determining an amount of total chlorine in a partially purified water sample is disclosed. The system includes a water machine that produces at least partially purified water including an at least partially purified water sample and a dialysis machine that provides a dialysis treatment to a patient. The dialysis machine receives the at least partially purified water from the water machine to prepare dialysis fluid for the dialysis treatment. The system also includes a total chlorine detector configured to receive the at least partially purified water sample, at a first time apply a source voltage to the at least partially purified water sample, and at a second time stop applying the source voltage to the at least partially purified water sample and instead monitor a sensed electrical parameter to determine an amount of total chlorine in the at least partially purified water sample.
US11135343B2	Blood component pooling device, system and method A device for pooling a blood component stored in source containers includes a pump or pumps configured to pump a fluid in a first direction and a second direction and receive a pump line having a first end connected to the source containers. A pool clamp is configured to receive a pool line having a first end connected to a second end of the pump line and a second end connected to a pool container. A wash clamp is configured to receive a wash line having a first end connected to the second end of the pump line and a second end connected to a wash media container. A controller is configured to open the pool clamp, close the wash clamp and operate the pump in the first direction and to alternatively close the pool clamp, open the wash clamp and operate the pump in the second direction.
US11135341B2	Platelet-derived growth factor composition and methods for the treatment of tendon and ligament injuries The invention provides compositions and methods for treatment of tendon and ligament injuries and/or repair of damaged tendons and ligament. The invention provides compositions comprising a biocompatible matrix and platelet-derived growth factor (PDGF).
US11135339B2	Orthopaedic implant An orthopaedic implant comprising a titanium substrate having silver deposited thereon, wherein the silver is operable to be eluted at a rate of at least 0.25 μg/cm2 24h-1, for at least 14 consecutive days, in use. The invention also extends to a method of producing an orthopaedic implant and use of the same.
US11135336B2	Thin-film vehicles that stabilize highly reactive active ingredients A method of protecting an active ingredient before using as a skin treatment includes packaging the active ingredient in a water soluble polysaccharide. The package includes a substrate, comprising a first and second side configured to bring together the water soluble polysaccharide with the active ingredient and a hydrogel, wherein the first side includes the water soluble polysaccharide with the active ingredient on the exterior, and the second half includes the hydrogel on the exterior. Once brought into contact for a sufficient time to allow the polysaccharide to dissolve, at least the hydrogel layer with the infused active ingredient can be peeled from the substrate to use as a facial mask for treating the skin with the active ingredient.
US11135335B2	Elastomeric films having low tear propagation Multilayer thermoplastic films, and laminates and articles comprising the films, wherein the film comprises at least one inner layer and at least two outer layers, wherein the inner layer comprises a polymeric composition comprising from about 55% to about 95% of one or more non-hydrogenated styrenic block copolymers, olefinic block copolymers, or combinations thereo; and each outer layer comprises at least 20% polypropylene and has a thickness of from about 5% to about 15% of the total film thickness, and further wherein the film has a constant force tear propagation of about 20% or less.
US11135334B2	Method of air disinfection and an air disinfection apparatus comprising an unipolar corona discharge zone and an electrical field In a method and apparatus (10) for air disinfection a unipolar corona discharge zone (26) is formed between an ionizing portion (15) of a first electrode (14) and a non-ionizing second electrode (18) by applying high DC voltage (22′, 22″) across the first and second electrodes and water molecules in an air flow (25) conveyed through the corona discharge zone are converted to hydrogen peroxide molecules. An electric field (27, 27′, 27″) is generated across the air flow close to the corona discharge zone for preventing ions escaping from the corona discharge zone into the atmosphere. This allows a higher corona discharge current to be applied than would be permitted if ions were able to escape into the atmosphere, which results in a higher yield of hydrogen peroxide and increases the efficiency of disinfection. It also helps to prevent dust from settling on the ionizing portion (15).
US11135332B1	Chemosensory disorder trigger and management system A system for chemosensory disorder testing includes a scanner for scanning a unique identifier associated with a test subject. A scent dispensing unit dispenses a predetermined scent for the test subject responsive to receipt of a dispensing control signal. A user interface receives a test response input from the test subject based on a perception of the test subject of the predetermined scent dispensed by the scent dispensing unit. A central controller generates the dispensing control signal responsive to the unique identifier scanned by the scanner. The central controller further determines at least one of a pass test result or a fail test result responsive to a comparison of the test response input to a predetermined response associated with the predetermined scent. A relational database stores the pass test result or the fail test result at a location associated with the unique identifier associated with the test subject.
US11135330B1	System and method for disinfecting a structure A disinfecting system for sanitizing a structure having a fire suppression sprinkler system includes a main conduit positioned in the structure and that is in fluid communication with a water source and operable to carry a water stream downstream from the water source. The disinfecting system includes a disinfectant conduit having in fluid communication with a disinfectant reservoir and operable to carry a disinfectant stream downstream from the disinfectant reservoir, the disinfectant conduit being in fluid communication with the main conduit. A control valve is in fluid communication with the disinfectant main conduits, the control valve allowing one of the disinfectant or water streams to flow downstream in the main conduit. A master nozzle defining outlet holes is in fluid communication with the main conduit, is positioned downstream of the control valve, and is operably configured to spray a liquid into an interior area of the structure.
US11135329B2	Systems and methods for spraying of sanitizing or disinfecting compositions with improved compatibility This invention relates to systems, methods, and disinfecting compositions for spraying onto surfaces to be sanitized or disinfected. Methods may include providing an aqueous hypohalite disinfecting composition, and providing a spraying system that may include a hand-held spray nozzle through which the composition is sprayed during use, and a pump and associated tubing for conveying the composition to the hand-held spray nozzle. The tubing may be specifically selected to exhibit at least a 65% recovery (no more than 35% loss) of hypohalite after 24 hours of contact between the composition and the tubing. The method may further include conveying the composition from the reservoir to the spray nozzle, and spraying the composition through the nozzle, e.g., onto the target surface. A related system may include similar components. A dilute hypohalite disinfecting composition may be provided for use with the system and/or method. The system may allow interchangeable use of a quaternary amine disinfecting composition.
US11135324B2	Portable and disposable FAR-UVC device A handheld portable device for sanitizing a surface or air surrounding a surface. The handheld portable device includes a body that comprises a user input and a far-UVC illumination source disposed at the body. The handheld portable device also includes a power source for providing power to the far-UVC illumination source. Responsive to actuating the user input, such as by a user holding the handheld portable device, the far-UVC illumination source emits far-UVC illumination to sanitize the surface or the air surrounding the surface of pathogens.
US11135323B2	Production of Re-188/186 particles Provided is a process of producing activated particles comprising 188Re-isotopes and/or 186Re-isotopes by irradiating non-volatile and water-insoluble starting particles comprising a rhenium compound with neutrons. Further provided is a process of producing corresponding non-volatile and water-insoluble starting particles. Further provided are respective starting particles and activated particles, respectively, and a composition comprising a plurality of activated particles. The activated particles, and the composition comprising same are suitable for use in radionuclide therapy, and for cosmetic applications.
US11135320B2	Radioligands for pretargeted pet imaging and methods of their therapeutic use Described herein are Tz/TCO-based pretargeting strategies using an Al[18F]-NOTA-labeled tetrazine radioligand. This imaging strategy enables delineation of cancer at earlier time points compared to other imaging strategies and further decreases the radiation dose to healthy tissues compared to directly labeled antibodies. Al-based 18F imaging of small molecules, such as tetrazine, has not been previously achieved due to the decomposition of tetrazine during radiofluorination. Radiofluorination is advantageous over other radiolabeling methods because, in addition to having a shorter half-life, 18F is more readily available to produce and therefore integrated into hospital workflows.
US11135318B2	Half-curcuminoids as amyloid-beta PET imaging agents Provided herein are curcumin analogues that are able to interact with amyloid beta (Aβ) and to attenuate the copper-induced crosslinking of Aβ. Also provided herein are methods of using the compounds as imaging agents of amyloid beta and for the treatment of diseases associated with amyloid beta. Methods of preparing unlabeled and radiolabeled compounds useful for interacting with amyloid beta and pharmaceutical compositions are also provided.
US11135315B2	Composition for detecting biofilms on viable tissues A staining composition for use in making biofilm detectable on viable tissue wherein the composition preferentially stains the biofilm and comprises a staining agent in a quantity effective to stain the biofilm and render it detectable.
US11135314B2	Making and using in vitro-synthesized ssRNA for introducing into mammalian cells to induce a biological or biochemical effect The present invention relates to compositions, kits and methods for making and using RNA compositions comprising in vitro-synthesized ssRNA inducing a biological or biochemical effect in a mammalian cell or organism into which the RNA composition is repeatedly or continuously introduced. In certain embodiments, the invention provides compositions and methods for changing the state of differentiation or phenotype of a human or other vertebrate cell. For example, the present invention provides mRNA and methods for reprogramming cells that exhibit a first differentiated state or phenotype to cells that exhibit a second differentiated state or phenotype, such as to reprogram human somatic cells to pluripotent stem cells.
US11135311B2	Preparation of solid cyclodextrin complexes for ophthalmic active pharmaceutical ingredient delivery The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 μm.
US11135310B2	Gold porphyrin-PEG conjugates and methods of use Disclosed are conjugates, compositions, and methods that include or use one or more gold(III) porphyrin complexes. Preferred conjugates are gold(III) porphyrin-poly(ethylene glycol) (PEG) conjugates. Preferred compositions and methods include or use such gold(III) porphyrin-PEG conjugates. Disclosed is a method for treatment of cancer comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of gold(III) porphyrin-poly(ethylene glycol) (PEG) conjugates. The gold(III) porphyrin-PEG conjugates can be in the form of nanostructures formed by self-assembly of the gold(III) porphyrin-PEG conjugates; or nanocomposites formed by encapsulation of other therapeutic agents by the nanostructures of gold(III) porphyrin-PEG conjugates.
US11135309B2	Poly(vinyl alcohol) nanocarriers The present invention provides a nanoparticle including at least one poly(vinyl alcohol) (PVA) having a molecular weight of from about 10 kDa to about 200 kDa, substituted with one or more moieties selected from: a therapeutic agent having a boronic acid moiety, wherein the therapeutic agent is covalently linked to the PVA via a boronate ester bond; a crosslinking group having a disulfide moiety, wherein the crosslinking group is covalently linked to the PVA, and a porphyrin, wherein the porphyrin is covalently linked to the PVA. Use of the nanoparticles for tumor detection and the treatment of diseases, including methods for photodynamic therapy and photothermal therapy, are also described.
US11135303B2	Pyrrolobenzodiazepines and conjugates thereof A conjugate of formula (A): where Y is selected from a single bond, and a group of formulae A1 or A2: where N shows where the group binds to the N10 of the PBD moiety; RL1 and RL2 are independently selected from H and methyl, or together with the carbon atom to which they are bound form a cyclopropylene group; CBA represents a cell binding agent; Q is independently selected from O, S and NH; R11 is either H, or R or, where Q is O, SO3M, where M is a metal cation.
US11135302B2	IGA FC-folate conjugates, pharmaceutical compositions and methods to treat cancer IgA-based Fc-folate conjugates as a treatment for cancer are provided. The conjugates utilize only the Fc portion of IgA to target its receptor on neutrophils (FcαR1) to elicit antibody-dependent cellular-cytotoxicity (ADCC).
US11135301B2	Triblock polypeptide-based nanoparticles for the delivery of hydrophilic drugs Described herein are compositions that may include a triblock self-assembling polypeptide and a molecule attached to the polypeptide. Also described herein are methods of making the compositions and methods of using the compositions.
US11135296B2	Pharmaceutical compositions of fumaric acid esters Pharmaceutical compositions and dosage forms of (N,N-diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and/or methyl 4-morpholin-4-ylbutyl (2E)but-2-ene-1,4-dioate, containing low levels of certain impurities are disclosed.
US11135293B2	Methods for photodynamic therapy A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.
US11135292B2	Multi-specific antibodies for cross-neutralization of multiple filovirus glycoproteins Methods for treating and for preventing filovirus infections are disclosed, as well as compositions therefor.
US11135286B2	Composition for treating and/or preventing Hepatitis B virus infection and the use thereof A composition for treating and/or preventing Hepatitis B virus infection and Hepatitis B virus infection mediated diseases and the method thereof are provided. In some embodiments, the composition includes a polyriboinosinic acid-polyribocytidylic acid (PIC), at least one antibiotic or polyamide compound, at least one positive ion, and Hepatitis B virus surface antigen. In some embodiments, the composition includes PIC, at least one antibiotic or polyamide compound, at least one positive ion, Hepatitis B virus surface antigen and Hepatitis B virus core antigen. The present disclosure also relates to a method of treating and/or preventing Hepatitis B virus infection, particularly for treating chronic HBV infection.
US11135283B2	Retroviral vector for the administration and expression of replicon RNA expressing heterologous nucleic acids The present disclosure relates generally to gene delivery using a chimeric, retroviral-RNA replicon vector particle for increased expression of transgenes in a host cell. In particular, the chimeric vectors described herein can be used in any of a variety of settings including gene therapy and vaccine settings.
US11135278B2	Pharmaceutical composition comprising attenuated Streptococcus pneumoniae strains and use thereof Provided is a pharmaceutical composition including attenuated Streptococcus pneumoniae strains, and a method thereof for prevention or treatment of inflammatory diseases, respiratory viral infections, bacterial infectious diseases, or allergic diseases.
US11135276B2	Method of making PDIA2 and compositions containing PDIA2 A method for producing soluble PDIA2, compositions containing it, and methods for its use.
US11135274B2	MRNA for use in treatment of human genetic diseases Compositions for modulating the expression of a protein in a target cell comprising at least one RNA molecule which comprises at least one modification 5 conferring stability to the RNA, as well as related methods, are disclosed.
US11135273B2	Sequence specific antimicrobials Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.
US11135265B2	Vasopressin formulations for use in treatment of hypotension Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time at temperatures higher than room temperature when formulated with the polymers. The polymers used in the present invention can decrease the degradation of the constituent peptides of the peptide formulations.
US11135256B2	Pharmaceutical composition and use thereof for ischemia treatment A pharmaceutical composition for ischemia treatment of a patient includes a ginkgo extraction and a pharmaceutically acceptable carrier. The dosage form of the pharmaceutical composition is gel, transdermal patch, cream or paste. The patient is a neonate, an infant, or an early child. A use of the pharmaceutical composition for ischemia treatment of a patient is disclosed.
US11135248B2	Stem cells from urine and methods for using the same Provided herein are stem cells and methods for producing a culture of stem cells from urine. The stem cells may be differentiated into an osteogenic, chondrogenic, adipogenic, endothelial, neurogenic or myogenic lineage. Methods of use of the cells are provided, including methods of treating a subject in need of a cell based therapy.
US11135246B2	Peptides and combination of peptides for use in immunotherapy against leukemias and other cancers The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11135244B2	Stem cell culture media and methods of enhancing cell survival The invention provides improved methods for preparing hematopoietic cells for transplantation and the resulting improved hematopoietic cell compositions. The invention further relates to improved culture media and methods of culturing, processing, modulating, and expanding blood cell products for hematopoietic transplantation.
US11135234B2	Effective aminoglycoside antibiotic for multidrug-resistant bacteria A compound represented by the following general formula (I) or a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutical composition thereof, and the use thereof to prevent or treat infectious diseases and a method to prevent or treat infectious diseases using those regimen are disclosed. The compound represented by formula (I) has an antibacterial activity against both gram-positive and gram-negative bacteria, and is useful in the prevention or treatment of infectious diseases caused by these bacteria.
US11135233B2	Methods for preventing or mitigating acute allergic responses using human milk oligosaccharides A method for preventing or mitigating an acute allergic response in a subject is disclosed. The method includes a step of administering a nutritional composition to the subject. The nutritional composition includes at least one of an acidic or a neutral HMO, but does not include an N-acetyl-lactosamine.
US11135232B2	Compositions for use in the prevention or treatment of necrotizing enterocolitis in infants and young children The invention discloses a composition comprising an oligosaccharide mixture, said oligosaccharide mixture comprising from 40 to 80 wt % of fucosylated oligosaccharide(s), from 10 to 50 wt % of N-acetylated oligosaccharide(s), from 5 to 40 wt % of sialylated oligosaccharide(s) and from 0 to 20 wt % of precursor(s) of human milk oligosaccharide, for use in preventing and/or in treating necrotizing enterocolitis in infants and young children.
US11135228B2	Cysteinyl-proresolving mediators that promote resolution of infection and organ protection A family of bioactive compounds identified in self-resolving inflammatory exudates is disclosed. The compounds give UV chromophores characteristics of a conjugated triene double bond system coupled to an auxochrome allylic to the triene. Further elucidation of the compounds reveals that they have an oxylipin backbone conjugated to a peptide or amino acid moiety via an auxochrome. In some embodiments the auxochrome is sulfur. However, the auxochrome may be NH, CH2 or O. The compounds have potent bioactivity, in vitro, and, in vivo, including promoting resolution of infection, stimulating macrophage phagocytosis of bacteria; protecting tissues from neutrophil mediated damage, promoting tissue repair and regeneration and preventing or limiting second organ reflow/reperfusion damage.
US11135224B2	Methods of sensitizing estrogen receptor positive (ER+) breast cancer cells to endocrine therapy Aspects of the technology are directed to a method of increasing sensitivity of estrogen receptor positive (ER+) breast cancer cells to treatment with an endocrine therapy. The method involves selecting ER+ breast cancer cells, and administering to the selected cells (i) one or more mammalian target of rapamycin (mTOR) inhibitors and (ii) one or more MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1) inhibitors in an effective amount to increase the sensitivity of the ER+ breast cancer cells to treatment with the endocrine therapy. Methods of treating a subject having ER+ breast cancer are also disclosed.
US11135220B1	Methods of treating viral infections with formulated compositions comprising 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione This disclosure provides, among other things, formulated oltipraz compositions comprising stabilized oltipraz crystals, for use in treating a patient who has a viral infection or is at risk of incurring a viral infection. Such viral infections can include a viral infection caused by a coronavirus such as one associated with MERS or SARS, e.g., SARS-CoV-2.
US11135212B2	Method for treating osteoporosis, osteopenia or low bone mineral density A method for treating osteoporosis and related methods are disclosed. The methods generally comprise administering to a patient in need of treatment an effective amount of tris(8-quinolinolato)gallium(III) or an analog thereof.
US11135211B2	Pimavanserin for treating impulse control disorder A method for treating a impulse control disorder in a patient comprising administering to the patient an effective amount of pimavanserin or a pharmaceutical acceptable salt thereof.
US11135207B2	Inhibitors of dihydroceramide desaturase for treating disease Disclosed herein are dihydroceramide desaturase 1 (Des1) inhibitor compounds and compositions, which are useful in the treatment of diseases, such as metabolic, cardiovascular, fibrotic, autoimmune/chronic inflammatory diseases, cystic fibrosis, various cancers, neurodegenerative diseases, lipid storage disorders, and ischemia/reperfusion injury, where inhibition of Des1 is expected to be therapeutic to a patient. Methods of inhibition of Des1 activity in a human or animal subject are also provided.
US11135206B2	Pyrazolo[4,3-c]quinoline derivatives for inhibition of β-glucuronidase The present invention provides novel pyrazolo[4,3-c]quinoline derivatives exhibiting specifically inhibition activity to microbiota β-glucuronidase, whereby providing potent activities to prevent chemotherapy-induced diarrhea (CID) of cancers. Therefore, the compounds of the present invention can be used as (1) chemotherapy-adjuvant to prevent chemotherapy-induced diarrhea (CID) and enhance chemotherapeutic efficiency of cancers; (2) health-food supplement to prevent the carcinogens induced colon carcinoma.
US11135201B2	Compositions to improve the therapeutic benefit of bisantrene and analogs and derivatives thereof The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof. Such methods and compositions are particularly useful for treatment of malignancies.
US11135200B2	Antimicrobial drug synthesis and therapeutic compositions This invention relates to the medical use of an antimicrobial agent, racemic Ornidazole, its (R) and (S) enantiomers, or pharmaceutically acceptable salts or esters thereof, and to methods of treatment which involve treating a subject with Ornidazole. The racemic (rac)-ornidazole, its enantiomers, or pharmaceutically acceptable salts or esters thereof, may be used in combination with other actives. The invention also relates to pharmaceutical formulations and compositions comprising (rac)-ornidazole, (R)-ornidazole, (S)-ornidazole, or pharmaceutically acceptable salts or esters thereof, and/or other actives as well as methods to stereoselectively manufacture the enantiomers.
US11135199B2	Sublingual pharmaceutical compositions of edaravone and (+)-2-borneol A sublingual tablet pharmaceutical composition containing edaravone and (+)-2-borneol, and a preparation method thereof. The sublingual tablet pharmaceutical composition includes edaravone, (+)-2-camphanol, an excipient, a filler, a binder, a disintegrant, and a lubricant. The excipient is selected from one or more of mannitol, lactose, dextran, cysteine, glycine, copovidone, and beta-cyclodextrin.
US11135192B2	Inhibitors for treating diseases characterized by atrial enlargement or remodeling The present invention relates to the NEP inhibitor pro-drug N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid ethyl ester, or a pharmaceutically acceptable salt thereof; or the NEP inhibitor N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid, or a pharmaceutically acceptable salt thereof, pro-drug for use in the treatment, prevention or delay of progression of a disease characterized by atrial enlargement and/or remodeling; a method for treatment, prevention or delay of progression of a disease characterized by atrial enlargement and/or remodeling comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of the NEP inhibitor or the NEP inhibitor pro-drug, or a pharmaceutically acceptable salt pro-drug thereof, to a subject, e.g. a human subject, in need of such treatment. The present invention further relates to a pharmaceutical composition or a commercial package comprising the NEP inhibitor or the NEP inhibitor pro-drug, or a pharmaceutically acceptable salt thereof, pro-drug for use in the treatment, prevention or delay of progression of a disease characterized by atrial enlargement and/or remodeling.
US11135188B2	Method and composition to improve absorption of therapeutic agents A tablet with an enhanced dissolution profile for a medicinally active ingredient such as aspirin and methods for making the tablet. The tablet comprises a blend of crystals of the medicinally active ingredient and a dissolution aid such as sodium or calcium carbonate or bicarbonate that coats the crystals upon co-milling. The blend is then compressed to form tablets that have an enhanced dissolution profile for the medicinally active ingredient.
US11135184B2	Formulations for epidermal repair The present disclosure is directed to dermatological formulations and their use for treating a variety of dermatological diseases and disorders, and for repairing and restoring a disrupted epidermal barrier, inhibiting inflammation, restoring a proper environment for maintaining a balanced symbiotic microbiome, and inhibiting the growth of pathogenic microorganisms in the epidermis—the outer layer of mammalian skin.
US11135178B2	Thymol and carvacol for use in medicine The invention provides therapeutic methods comprising the administration of thymol or carvacrol, or a pharmaceutically acceptable salt or prodrug thereof. The methods are useful for modulating muscle atrophy, performance, recovery, generation, or maintenance in animals.
US11135177B2	Methods of making and using compositions comprising flavonoids The subject invention relates to novel micoparticulate and soluble forms of flavonoids, and their synthesis. The invention also includes novel formulations of such flavonoids. Further, the invention includes novel methods of manufacturing the flavonoid formulations. The invention also relates to a wide variety of applications of the flavonoid formulations.
US11135176B1	Formulations of topical ibuprofen SLN gel using HME technique A continuous process for preparing a solid lipid nanoparticle of ibuprofen utilizing hot melt extrusion which avoids additional steps such as high-pressure homogenization, ultrasonication, or solvent evaporation. The continuous process includes preparing a pre-emulsion comprising a lipid, and continuously processing the pre-emulsion through a hot melt extruder device.
US11135174B2	Coated mesoporous nanoparticles Provided are methods for producing mesoporous nanoparticles that can, once loaded, retain small or large molecules (e.g., molecules having a molecular weight that is less or greater than about 900 Da) until release is desired, upon which time the mesoporous nanoparticles can release the loaded molecule in a controlled manner for a desired period of time, including an extended period of time. Also disclosed are methods for treating a subject comprising administering to the subject a mesoporous nanoparticle according to the present disclosure.
US11135173B2	Prolonged release pharmaceutical composition comprising cysteamine or salt thereof A prolonged release multiple unit dosage form, preferably pellets, of cysteamine, cystamine or a pharmaceutically acceptable salt thereof, preferably cysteamine bitartrate, with a non gastro-resistant coating is described. The dosage form is particularly indicated for the administration to patients once or twice a day and it can be used also for pediatric administration.
US11135164B2	Reloadable hydrogel system comprising an anti-PEG antibody for treating myocardial infarction A drug delivery system and methods of using such for delivering a peglyated therapeutic agent to heart. The drug delivery system may comprise an antibody embedded in a hydrogel, comprising one or more biodegradable polymers, up to about 60% of which contain inter-chain or intra-chain covalent crosslinks.
US11135159B2	Optimized high-dose mesalazine-containing tablet The present invention relates to an oral enteric high-dose tablet comprising mesalazine as the active substance as well as its use.
US11135157B2	Oral tablet for delivery of active ingredients to the throat The invention relates to an oral tablet for delivery of active ingredients to the throat comprising a population of particles and an active ingredient to be delivered to the throat, the population of particles comprising directly compressible (DC) and non-directly compressible (non-DC) sugar alcohol particles, the non-DC particles providing the tablet with a plurality of discrete non-DC areas, the non-DC areas resulting in induced saliva generation upon mastication of the tablet, wherein the tablet is designed to be masticated and designed to deliver the active ingredient to the throat as part of the saliva generated upon mastication of the tablet.
US11135156B2	Pharmaceutical tablet for use in administering one or more pharmaceutically active ingredients A pharmaceutical tablet for use in administering one or more pharmaceutically active ingredients, comprising a polymer system, the one or more pharmaceutically active ingredients, a flavor, and a sweetener, wherein at least 20% by weight of the pharmaceutical tablet comprises substantially non-elastomeric polymer and less than 5% by weight of the pharmaceutical tablet comprises one or a combination of elastomeric polymers, and wherein the pharmaceutical tablet comprises at least 70% by weight of said polymer system comprising polyvinyl acetate (PVA) and less than 10% by weight of said polymer system comprising polymer having a molecular weight (Mw) greater than 50,000 g/mol.
US11135155B2	Liquid naloxone spray The invention provides stable liquid formulations containing naloxone, a pharmaceutically acceptable salt or a derivative thereof. The invention further provides methods for treating opioid overdose, opioid dependence, and congenital insensitivity to pain with anhidrosis by administering the liquid formulations of the present invention intranasally to a patient in need thereof. Further, the invention provides a method of treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering intranasally the naloxone formulations of the present invention.
US11135153B2	High penetration composition and uses thereof The present invention relates to compositions and uses of novel high penetration compositions or high penetration prodrugs (HPP), in particular HPPs for 4-aminophenol derivatives, which are capable of crossing biological barriers with high penetration efficiency. The HPPs herein are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, due to the ability of penetrating biological barriers, the HPPs herein are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPPs herein can be administered to a subject through various administration routes. For example, the HPPs can be locally delivered to an action site of a condition with a high concentration due to their ability of penetrating biological barriers and thus obviate the need for a systematic administration. For another example, the HPPs herein can be systematically administer to a biological subject and enter the general circulation with a faster rate.
US11135151B2	Cosmetic compositions containing oxazoline functionalized polymers and compound having at least one nucleophilic site capable of reacting with the at least one oxazoline functionalized compounds Disclosed are compositions, systems and methods for treating keratinous fibers such as hair. The compositions and systems comprise an oxazoline functionalized polymer and a compound having at least one nucleophilic site capable of reacting with the at least one oxazoline functionalized compound and chosen from hydroxyl group-containing compounds, thiol group-containing compounds, and a mixture thereof. The compositions and methods are employed to improve the quality of the keratinous fibers.
US11135150B2	Compositions and methods for improving the quality of chemically treated hair The present disclosure relates to hair care compositions for chemically treating hair, to kits comprising the compositions, and to methods for treating hair with the compositions. The compositions include one or more polymeric acid compounds and/or polymeric acid anhydride compounds in addition to one or more active agents for chemically treating the hair. Additionally, the compositions can optionally include one or more non-polymeric, mono-, di-, and/or tri-carboxylic acids and/or one or more mono- and/or di-amines and/or polyamines. Hair treated with the compositions exhibits improved softness, smoothness, and discipline.
US11135146B2	Peroxide-less biophotonic compositions and methods The present disclosure provides biophotonic topical compositions, kits and their uses. In some aspects, the biophotonic topical compositions of the present disclosure comprise a first chromophore, a salt selected from one or more bicarbonate or carbonate salts or a combination of the foregoing salts, and one or more gelling agents. In some aspects, the biophotonic topical compositions of the present disclosure comprise a first chromophore, one or more polyols, and one or more gelling agents. The biophotonic compositions of the present disclosure do not include an oxidant selected from the group consisting of a peroxide, a peroxy acid, hydrogen peroxide, carbamide peroxide, an alkali metal peroxide, an alkali metal percarbonate, peroxyacetic acid, and an alkali metal perborate. The biophotonic compositions are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
US11135142B2	Dentifrice compositions comprising tin ions A dentifrice composition with tin, calcium, and a pH of greater than 7. A dentifrice composition with tin, fluoride, calcium abrasive, water, and a pH of greater than 7. Dentifrice compositions with a high tin ion availability. Dentifrice compositions comprising stannous fluoride and/or stannous chloride in combination with calcium carbonate.
US11135140B2	Aerosol device based on sebum-absorbing powder and calcium carbonate The present invention relates to an aerosol device comprising a container containing: one or more propellants, and a composition comprising: one or more sebum-absorbing powders with a sebum uptake of greater than or equal to 35 ml/100 g; one or more styling powders comprising calcium carbonate; less than 10% by weight of one or more C2-4 monoalcohols relative to the total weight of the composition, the propellant(s) possibly being present in the composition or, in the container, separate from the composition. The invention also relates to a process for the dry-washing and cosmetic treatment of keratin materials, comprising a step of applying to the hair the cosmetic composition, sprayed from the aerosol device.
US11135120B2	System and device for guiding and detecting motions of 3-DOF rotational target joint Examples of a device for guiding and detecting a motion of a target joints and a motion assistance system such motion guiding devices are described. The motion guiding and detecting device comprises a motion generator and a motion transfer and target interfacing unit to transfer the motion generated by the motion generator to the target joint. The system further includes a motion detection and feedback unit that interfaces with the target, and a controller that interfaces with both the feedback unit and the motion generator to control and coordinate the motion of the motion generator and the target joint.
US11135119B2	Adaptable robotic gait trainer A gait training system has a motor connected to a first linkage system by an actuator. The first linkage system has multiple linkage members connected to multiple joints and an endpoint that is configured to produce a cyclic gait motion when the motor is activated. First and second linkage members have an adjustable length. A method of customizing a gait pattern on a gait training system is also described.
US11135114B2	Medical shelf A medical shelf for holding surgical instruments in a convenient location during obstetric care. The medical shelf includes a tray having pair of arms extending from opposing ends of a rear side thereof, wherein the arms can mount to an end of a birth delivery bed. In a mounted position, the tray provides a surface that can receive surgical instruments to allow a medical professional the ability to conveniently access the instruments while performing a procedure on a patient positioned on the bed. A first brace secures each arm to the tray in a perpendicular position and a second brace secures each arm in an L-shaped configuration. A lip is disposed around a perimeter of the tray. A gap is disposed between the arms to allow the medical professional positioned on a front side of the tray to access the patient positioned on the opposing side of the tray.
US11135113B2	Bodyweight decompression table Decompression table embodiments are described that provide body weight support distributed along the body by providing a lumbar support harness as well as separate foot and leg attachment elements, Other embodiments may either alone or in combination with body weight support elements may provide elements for placing the body in a pre-stretched configuration during decompression by curving the body support portion of the table and strategically adding controlled spacing from the cervical and lumbar areas to the table surface.
US11135107B2	Absorbent, disposable, re-fastenable undergarment The present invention protects a refastenable disposable absorbent pant, comprised by a chassis, left and right front side panels, and left and right rear side panels, in such a way that the left and right front side panels are joined to the left and right rear side panels, respectively, by means of a refastenable seal, such that the pant has an arrangement suitable to be pulled up and down through the legs, with a waist opening and a pair of leg openings, such that the left and right front panels are wider than the left and right rear panels, and the refastenable seal is placed at the rear part of the pant, between the side flanks thereof and the longitudinal edges of the chassis.
US11135103B2	Apertured webs and methods for making the same A patterned apertured web includes a plurality of land areas in the patterned apertured web and a plurality of apertures defined in the patterned apertured web. At least some of the land areas surround at least some of the apertures. The patterned apertured web has an Effective Open Area in the range of about 5% to about 50%, according to the Aperture Test. The patterned apertured web has a plurality of Interaperture Distances, according to the Aperture Test. The Interaperture Distances have a distribution having a median and a mean. The mean is greater than the median.
US11135100B2	Absorbent articles comprising stretch laminates An absorbent article includes a chassis comprising a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet, and at least one elastically elongatable panel joined to the chassis. The elastically elongatable panel includes an ultrasonically bonded stretch laminate. The stretch laminate includes a first nonwoven and a second nonwoven, and an elastomeric film sandwiched between the first and second nonwovens. The elastomeric film has two surfaces and a skin on at least one of the surfaces. The stretch laminate further incudes a first zone and second zone. In the second zone, the laminate is elastically extensible in a stretch direction. In the first zone, the laminate is unactivated and the elastomeric film comprises activation stripes.
US11135093B2	Patient interface for ophthalmic surgery In certain embodiments, a patient interface apparatus for ophthalmic surgery comprises an annular member and an evacuation conduit. The annular member has an outer side, an inner side, a distal side, and a proximal side. The inner side defines an opening that allows for a laser beam to reach a treatment region of an eye free from reflection or refraction. The proximal side has a contact surface shaped to affix to a surface of the eye, and a groove that defines a suction chamber with the surface of the eye. The evacuation conduit is capable of fluid communication with the suction chamber, and conducts fluid away from the suction chamber to affix the contact surface to the surface of the eye.
US11135087B2	Devices, systems, and methods for the treatment of clogged glands of the eye A heated eye mask for treating clogged glands of an eye includes a mask body. The mask body includes an outer layer of surface material configured to be positioned away from an eye region of and an inner layer of surface material configured to contact the eye region, a heating element assembly disposed between the outer and inner layers of surface material in a therapeutic region of the mask body, and a thermally conductive material in contact with the heating element and disposed between the heating element and the second layer of surface material to evenly distribute heat across the therapeutic region of the mask body. The heated eye mask further includes an electrical cord configured to be coupled with a power source and in communication with the heating element and an adjustable strap to maintain contact of the mask body with the eye region of the user.
US11135081B2	Method for automating custom-fitting joint brace An automated method for applying specific geometric constraints to a starter file and considering external specifications outside of fit to achieve an optimized, restorative joint brace or orthotic device. External specifications may include indications of the patient, biometric data, data from prescribing doctors, X-ray data, MRI data, joint geometry to restore optimized function, and envelope of motion. After the fitting process, the starter file undergoes a process of exact commands in order to finish and/or add additional features. With a vertical integration from scanning an object to producing the custom fitted device, the product can be manufactured at scale more rapidly and at lower cost, improving access to superior devices at a reasonable price to the consumer.
US11135076B2	Tubular sleeve and system for the atraumatic treatment of hollow organs The invention relates to a tubular sleeve for the atraumatic treatment of hollow organs, wherein the sleeve is folded in an initial state and can be unfolded in order to lie against an inner wall of a hollow organ in a final state. The sleeve is characterized in that the sleeve is formed of an outer wall and an inner wall, which are arranged concentrically to each other, wherein the outer wall and the inner wall are tightly connected to each other at ends thereof in such a way that an approximately tubular compartment is formed in the region between the outer wall and the inner wall and the folding of the sleeve is directed about a sleeve longitudinal axis.
US11135068B2	Interbody fusion implant An intervertebral implant can include a core and a flexible end plate. The core can have a core body that is elongate along a first direction and defines first and second outer surfaces. The flexible end plate can define an inner surface and an opposed bone facing surface that is configured to abut a vertebral body. The flexible end plate can be coupled to the core such that at least a portion of the inner surface faces the first outer surface and is spaced from the first outer surface. The flexible end plate is configured to resiliently flex toward a compressed configuration such that as the flexible end plate flexes toward the compressed configuration, a first end moves relative to the core along the first direction and the portion of the inner surface moves toward the first outer surface.
US11135067B2	Orthopedic augments having recessed pockets Systems, devices and methods for providing orthopedic augments having recessed pockets that receive a fixation material. The orthopedic augments include an outer surface that interfaces with a patient's tissue or bone, an inner surface that interfaces with an implant and having a recessed pocket configured to receive a fixation material, a rim around at least a portion of the recessed pocket, and a port in the rim, wherein the recessed pocket extends along the inner surface in at least a lateral direction from the port.
US11135065B2	3-D printed orthopedic implants A spinal interbody implant is fabricated using 3-D printing to provide an engineered structure of one or more porous, permeable, or non-solid portions with or without one or more solid, dense, or micro-dense portions. The porous, permeable, or non-solid structure can be a mesh, lattice, web, weave, honeycomb, simple cubic, tetrahedral, diamond, or otherwise with the number and size of its pores, holes, perforations, or openings, as well as the distance or thickness between them, can vary accordingly. Some portions of the porous, permeable, or non-solid structure(s) may have porosities and/or thicknesses different than other portions. The solid, dense, or micro-dense structure may be constant throughout the body of the implant or may be a range of densities throughout the body of the implant. Alternately, one or more portions of the implant may have a range of densities throughout its body ranging from solid to a maximum porosity.
US11135053B2	Implantation method of artificial heart valve The present application provides an implantation method of an artificial heart valve. The implantation method can include forming an incision in the left chest to expose the ventricle; advancing a guide wire kept away from chordae tendineaes through the atrium into the ventricle; advancing a guide wire catcher into the ventricle from the incision to pull out the distal end of the guide wire from the ventricle; and advancing the artificial heart valve into the ventricle from the distal end of the guide wire with a valve deliverer, and placing the artificial heart valve at a primary valve between the ventricle and the atrium along the guide wire. The artificial heart valve may avoid the chordae tendineaes in the heart system through the guide wire track during implantation.
US11135046B2	Animal splint An animal splint for immobilizing a leg of an animal receives the back and sides of the injured leg and is angularly adjustable to the normal angle of the upper and lower part of the injured leg prior to sustaining the leg injury. The splint includes a lower leg assembly, an upper leg assembly, an adjustment member configured for setting the angle between the lower leg assembly and the upper leg assembly, and a leg retaining means that extends across the lower leg open front and the upper leg open front where the lower leg assembly and the upper leg assembly receives the back and sides of the injured leg.
US11135040B2	Dental device A dental device comprising: a handle and; a stem. The stem having a tip with an end. The tip has a first groove winding therearound extending from a first distal point proximate the end towards the handle at least one complete turn around the tip to a first-groove termination point. The stem has a first flange projecting outward therefrom and winding therearound. The first flange extends away from the handle from a first proximal point towards the end of the tip to a first-flange termination point. At least a portion of the stem having the first groove and at least a portion of the first flange is suitable for insertion into an area between two teeth, whereby the area between the teeth may be cleaned by the at least a portion of the stem inserted between the teeth.
US11135039B2	Intraoral scanner that compensates for optical inaccuracies A non-transitory medium includes instructions for generating a three-dimensional virtual model of an intraoral object by receiving surface scan data of the intraoral object while changing a position of at least one lens of focusing optics of an intraoral scanner, wherein the surface scan data comprises data for a plurality of points of the intraoral object, and adjusting the data for one or more of the plurality of points to compensate for one or more inaccuracies associated with at least one of a) different temperatures or b) different positions of the at least one lens. A three-dimensional virtual model of the intraoral object is generated using the adjusted data.
US11135036B2	Computer-based method for measuring positional relationship between two teeth In one aspect, the present application provides a computer-based method of measuring positional relationship between two teeth, comprising: obtaining a second 3D digital model representing a plurality of teeth under a second tooth arrangement, wherein the plurality of teeth comprise a first tooth and a second tooth; and measuring a value of a collision or a size of a gap between the first tooth and second tooth based on the second 3D digital model and in a predetermined first direction.
US11135034B2	Signal tag detection components, devices, and systems Provided herein are systems, devices, assemblies, and methods for localization of a tag in a tissue of a patient. For example, provided herein are systems, devices, and methods employing a detection component that is attached to or integrated with a surgical device, where the detection component detects a signal from a tag in a patient, where the tag is activated by remote introduction of a magnetic field.
US11135025B2	System and method for registration between coordinate systems and navigation Disclosed is a system for assisting in guiding and performing a procedure on a subject. The subject may be any appropriate subject such as inanimate object and/or an animate object. The guide and system may include various manipulable or movable members, such as robotic systems, and may be registered to selected coordinate systems.
US11135023B2	Robotic surgery system including position sensors using fiber bragg gratings An apparatus comprises a surgical instrument mountable to a robotic manipulator. The surgical instrument comprises an elongate arm. The elongate arm comprises an actively controlled bendable region including at least one joint region, a passively bendable region including a distal end coupled to the actively controlled bendable region, an actuation mechanism extending through the passively bendable region and coupled to the at least one joint region to control the actively controlled bendable region, and a channel extending through the elongate arm. The surgical instrument also comprises an optical fiber positioned in the channel. The optical fiber includes an optical fiber bend sensor in at least one of the passively bendable region or the actively controlled bendable region.
US11135016B2	Augmented reality pre-registration The disclosed method encompasses pre-registering an anatomical body part with a coordinate system used by an augmented reality device (such as augmented reality glasses) for outputting (e.g. displaying or projecting) augmentation information. An example of the augmentation information is the position (in the real image captured by the augmented reality device) of a fine registration area on the anatomical body part which a user is supposed to identify for fine registration of the anatomical body part with a tracking coordinate system used by a medical position tracking system. The disclosed method is usable in a medical environment such as for surgery or radiotherapy.

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