Document Document Title
US11130965B2 Insecticidal proteins
Compositions and methods for controlling plant pests are disclosed. In particular, novel insecticidal proteins having toxicity on coleopteran and/or lepidopteran insect pests are provided. Nucleic acid molecules encoding the novel insecticidal proteins are also provided. Methods of making the insecticidal proteins and methods of using the insecticidal proteins and nucleic acids encoding the insecticidal proteins of the invention, for example in transgenic plants to confer protection from insect damage, are also disclosed.
US11130964B2 Insect inhibitory proteins
Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, TIC11239, TIC11243, TIC11256, TIC4544, TIC4545, TIC6871, TIC7429, TIC7497, TIC7511, TIC7513, TIC7518, TIC7524, TIC7526, TIC7528, TIC7535 and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
US11130960B2 Methods for conferring or enhancing herbicide resistance on plants and/or alga with protoporphyrinogen oxidase variants
Provided are methods for conferring and/or enhancing herbicide resistance on plants or algae including agricultural crops by introducing prokaryote-derived protoporphyrinogen oxidase variants.
US11130959B2 Methods and compositions for combinations of mutations associated with herbicide resistance/tolerance in rice
Rice is described that is tolerant/resistant to herbicides, for example, ACCase inhibitors, and HPPD inhibitors, or both. For ACCase inhibitors, 2 different chromosome regions act synergistically in providing resistance/tolerance to the same herbicide class. Use of the herbicide resistant/tolerant rice for weed control and methods of producing tolerant/resistant rice are also disclosed.
US11130955B2 Applications of CRISPRi in high throughput metabolic engineering
Methods, compositions, and kits for high throughput DNA assembly reactions in vitro. Modular CRISPR DNA constructs comprising modular insert DNA parts flanked by cloning tag segments comprising pre-validated CRISPR protospacer/protospacer adjacent motif sequence combinations. High throughput methods of CRISPRi and CRISPRa.
US11130951B2 Modulating the cellular stress response
Methods of using B2 or Alu nucleic acids, or antisense oligonucleotides that modulate the EZH2/B2 or EZH2/Alu interaction and have the capacity to alter cleavage of B2 and Alu RNA, for increasing or decreasing cell and organismal viability.
US11130945B2 Glucuronosyltransferase, gene encoding same and use thereof
Provided are an enzyme involved in a glycyrrhizin biosynthetic system, a gene of the enzyme and use thereof in order to stably and continuously provide a large amount of glycyrrhizin. Glucuronosyltransferase with an activity of further transferring glucuronic acid to the hydroxy group at the 2-position of glucuronic acid in an oleanane-type triterpenoid monoglucuronide is identified to provide the transferase, a gene for the transferase and use thereof.
US11130943B2 Culture medium
The invention relates to improved culture methods for expanding epithelial stem cells and obtaining organoids, to culture media involved in said methods, and to uses of said organoids.
US11130940B2 Device for in vitro culture of embryos and fabrication method thereof
A device for in vitro culture of embryos includes: an array having at least one well formed therein; and a bottom surface formed in the well and made of polydimethylsiloxane (PDMS). The use of the culture vessel having the well bottom surface made of PDMS has the effect of further increasing the blastocyst formation rate of embryos compared to the use of conventional arrays made of plastic.
US11130939B2 Bacteria for degrading ethylene oxide and uses thereof
The present disclosure relates to strains for degrading ethylene oxide and degradation agents comprising the same, wherein the strains are Acetobacter peroxydans EO-01 strain with Deposit number of CGMCC No. 18431; Lactobacillus fermentum EO-02 strain with Deposit number of CGMCC No. 18432; or Bacillus subtilis EO-03 strain with Deposit number of CGMCC No. 18433. The strains are capable of safely and efficiently degrading ethylene oxide. The present disclosure also provides a method for purifying and producing strains that can degrade ethylene oxide, and a method for biodegrading ethylene oxide.
US11130933B2 Wet wipes containing hydroxy acetophenone and cocamidopropyl PG dimonium chloride phosphate
A cleaning composition including a preservative formulation having hydroxy acetophenone and a phospholipid complex is disclosed. The cleaning composition can be loaded on a cleaning wipe and used for personal care. The hydroxyacetophenone provides a preservative booster to the preservative system for the cleaning composition containing a phospholipid complex, such as cocamidopropyl PG-dimonium chloride phosphate, which has some limited independent preservation activity, depending on the level in the final formulation.
US11130932B2 Body and pet wash organic foaming soap composition and dispenser
An organic liquid and foaming soap composition and dispenser for use as a human hand, body wash and a pet wash, comprising: a) a foam-able organic liquid soap composition comprising the anti-microbial active ingredients of: organic shea butter; USDA approved natural spearmint oil; USDA approved natural lime oil; organic thyme oil; organic rosemary extract; and, b) a portable or fixed, manual or automatic foaming soap dispenser. The organic soap composition may further comprise a base soap comprising: saponified organic coconut oil; organic olive oil; organic sunflower oil; organic jojoba oil; organic aloe vera; and glycerin. And the organic soap composition has a shelf-life of about three years, and able to eradicate about 74.6% through 77.6% of the bacterial strain Staphylococcus aureus after at least one minute of direct contact with the composition. The dispenser is a fixed wall or sink mounted, or a portable bottle, including a mini-foaming leave-on sanitizer.
US11130931B2 Compositions and methods for clearing tissue
A composition and a method for clearing tissue for subsequent three-dimensional analysis. The clearing composition comprises: (1) a homogenizing agent such as N-methylglucamine, urea, or ethylenediamine; (2) a cytoplasmic, water-soluble refractive index adjusting agent such as iohexol, sodium thiosulfate, or polyethylene glycol; and (3) a membrane, lipid-soluble RI adjusting agent such as 2,2′-thiodiethanol (TDE) or propylene glycol. The tissue clearing composition is particularly suitable for use with long-term fixed human tissues.
US11130930B2 Compositions for treatment and methods for making and using the same
A detergent composition, a method of making the detergent composition, and a method of use thereof are provided. The detergent composition comprises at least 0.001% by weight of an antimicrobial agent, based on the total weight of the composition; an enzyme; and at least 0.01% by weight of a hydrotrope, based on the total weight of the composition.
US11130929B2 Functionalized siloxane polymers and compositions comprising same
A siloxane polymer. A composition including the polymer. A method of treating and/or cleaning a situs using the same.
US11130921B2 Process for the preparation of a feedstock for a hydroprocessing unit and an integrated hydrotreating and steam pyrolysis process for the direct processing of a crude oil to produce olefinic and aromatic petrochemicals
Integrated hydrotreating and steam pyrolysis processes for the direct processing of a crude oil to produce olefinic and aromatic petrochemicals.
US11130920B1 Integrated process and system for treatment of hydrocarbon feedstocks using stripping solvent
Separation of asphaltenes from residual oil is carried out with naphtha as solvent. In particular, straight run naphtha obtained from the same crude oil source as the residual oil feed is used as the solvent. The mixture of deasphalted oil and solvent is passed to a hydroprocessing zone, without typical separation and recycle of the solvent back to the solvent deasphalting unit. Asphalt is separated from the residual oil (residue from atmospheric or vacuum distillation); the mixture of deasphalted oil and naphtha solvent is passed to the hydroprocessing unit.
US11130915B2 Methods for methanol-to-gasoline conversion with forwarding methanol processing
Methanol-to-gasoline (MTG) conversion may be performed with forward methanol processing. Methanol may be fed to a first reactor where it may be catalytically converted under dimethyl ether formation conditions in the presence of a first catalyst to form a product mixture comprising dimethyl ether (DME), methanol, and water. The DME may be separated from the methanol and the water and delivered to a second reactor. In the second reactor, the DME may be catalytically converted under MTG conversion conditions in the presence of a second catalyst to form a second product mixture comprising gasoline hydrocarbons and light hydrocarbon gas. The methanol and the water from the first reactor may be separated further to obtain substantially water-free methanol, which may be delivered to the second reactor. The separation of methanol from the water may be performed using the light hydrocarbon gas to effect stripping of the methanol.
US11130911B2 Liquid crystal compound and liquid crystal composition
A compound represented by formula I, a negative liquid crystal composition comprising such a compound, and a liquid crystal display element or liquid crystal display comprising the compound or liquid crystal composition are provided. The compound represented by formula I contains two hydroxy groups. In an ODF process for a panel, due to an intermolecular force between the hydroxyl groups and the surface of the panel (a glass surface or an ITO electrode surface), the compound is spontaneously aligned, in a standing manner, on the panel glass or transparent ITO electrode substrate, causing liquid crystal molecules similar to the compound represented by formula ITO be vertically aligned, and UV light irradiation, a polymer layer with a rough surface is formed on the substrate by means of polymerization, and achieves the effects of PI insulation and vertical alignment of the liquid crystal molecules.
US11130906B2 Brine resistant silica sol
A brine resistant silica sol is described and claimed. This brine resistant silica sol comprises an aqueous colloidal silica mixture that has been surface functionalized with at least one moiety selected from the group consisting of a monomeric hydrophilic organosilane, a mixture of monomeric hydrophilic organosilane(s) and monomeric hydrophobic organosilane(s), or a polysiloxane oligomer, wherein the surface functionalized brine resistant aqueous colloidal silica sol passes at least two of three of these brine resistant tests: API Brine Visual, 24 Hour Seawater Visual and API Turbidity Meter.
US11130904B2 Gravel packing fluids with enhanced thermal stability
Systems and methods for using gellable gravel packing fluids that may comprise polysaccharide gelling agents and gel stabilizers to extend the working temperature range for the polysaccharide gelling agents. A method for placing a gravel pack in a subterranean formation comprising: providing a gravel packing fluid in the form of a linear gel and comprising an aqueous base fluid, a polysaccharide gelling agent, a thermal stabilizer, and a gravel; placing the gravel packing fluid into the subterranean formation; and allowing the gravel packing fluid to form a gravel pack in the subterranean formation.
US11130898B2 Treatment fluids containing high density iodide brines
The present disclosure provides methods and systems for treatment fluids including an iodide brine. In some embodiments of the present disclosure, an oil-based treatment fluid in the form of an invert emulsion comprising an aqueous internal phase and an oil external phase, wherein the aqueous internal phase comprises an iodide brine is provided. The treatment fluid may be introduced into at least a portion of a well bore penetrating at least a portion of a subterranean formation.
US11130897B2 Thermally responsive viscosifiers in subterranean operations
Methods for the use of treatment fluids that include thermally responsive viscosifiers in subterranean formations are provided. In one embodiment, the methods include introducing a treatment fluid including an aqueous base fluid and a thermally responsive hydrogel including at least one thermoresponsive polymer into at least a portion of a subterranean formation; allowing the thermally responsive hydrogel to reach a thickening transition temperature, wherein the thermally responsive hydrogel undergoes a liquid-to-solid phase change at or above the thickening transition temperature; and allowing the treatment fluid to at least partially solidify in the subterranean formation, wherein the solid thermally responsive hydrogel is present in the treatment fluid in an amount from about 0.01 to about 0.2 by volume fraction of solids of the treatment fluid.
US11130887B2 Pressure-sensitive adhesive composition
The present application relates to a pressure-sensitive adhesive composition, an optical laminate, a pressure-sensitive adhesive polarizing plate and a display device. In the present application, a pressure-sensitive adhesive composition having all excellent physical properties such as endurance reliability and interface adhesiveness and being capable of minimizing light leakage occurring under high temperature or high-temperature and humidity conditions can be provided. The pressure-sensitive adhesive composition of the present application can be used for an optical film such as a protective film and a polarizing plate.
US11130884B2 Adhesive composition
An adhesive composition may include 100 parts by weight of a (meth)acrylic polymer (A), 45 to 65 parts by weight of isoboronyl acrylate (B), and 0.1 to 10 parts by weight of a photoradical polymerization initiator (C). Each molecule of the (meth)acrylic polymer (A) may have at least one group represented by the general formula (1) at a molecular terminal: —OC(O)C(R1)═CH2 (1), where R1 is a hydrogen atom or an organic group containing 1 to 20 carbon atoms. The (meth)acrylic polymer (A) may have a number average molecular weight (Mn) of 3,000 to 100,000, and a ratio (Mw/Mn) of a weight average molecular weight (Mw) to a number average molecular weight (Mn) of less than 1.8.
US11130883B2 Polishing composition
Provided is a polishing composition that includes a cellulose derivative and is effective for reducing surface defects after polishing. According to the present application, a polishing composition comprising an abrasive, a basic compound and a surface protective agent is provided. The surface protective agent contains a cellulose derivative and a vinyl alcohol-based dispersant. The surface protective agent has a dispersibility parameter α of less than 100.
US11130881B2 Coating compositions for packaging articles and methods of coating
This invention provides a polymer that is useful in a variety of applications, including as a binder polymer of a coating composition, and especially a packaging coating composition. Packaging articles (e.g., containers) comprising the polymer and methods of making such packaging articles are also provided.
US11130879B2 Dispersants, coating compositions including dispersants, and methods of forming the same
A graft copolymer is provided herein. The graft copolymer includes a polymeric backbone. The polymeric backbone includes a cyclic amine-containing moiety. The graft copolymer further includes a first side chain bound to the polymeric backbone, wherein the first side chain includes an acid-containing moiety. The graft copolymer further includes a second side chain bound to the polymeric backbone, wherein the second side chain includes an alkoxylated moiety. Another graft copolymer is provided herein. The graft copolymer includes a polymeric backbone. The polymeric backbone includes a quaternary ammonium moiety formed from a reaction of an amine-containing moiety and an alkylation agent. The graft copolymer further includes a first side chain bound to the polymeric backbone, wherein the first side chain includes an acid-containing moiety. The graft copolymer further includes a second side chain bound to the polymeric backbone, wherein the second side chain includes an alkoxylated moiety.
US11130876B2 Inkjet primer fluid
An example inkjet primer fluid includes an alkoxysilane, a surfactant, a co-solvent, and a balance of water; and is at least substantially colorless. In an example method, a primer fluid, including an alkoxysilane, a surfactant, a co-solvent, and a balance of water, is thermal inkjet printed from a thermal inkjet printhead to form a silicon dioxide film on a resistor. Then, a jettable composition, including suspended nanoparticles, is thermal inkjet printed from the thermal inkjet printhead. In another example method, suspended nanoparticles, an alkoxysilane, and a growth mediator are combined to form a mixture. The mixture is heated to a temperature ranging from about 60° C. to about 80° C. and stirred for about 12 hours to about 36 hours to form silicon dioxide coated, suspended nanoparticles. Then, a surfactant, a zwitterionic stabilizer, a co-solvent, and a balance of water are added to the mixture to form a stabilized, jettable composition.
US11130874B2 Hybrid photopolymer composition for additive manufacturing
The present invention refers to a hybrid photopolymer composition for additive manufacturing, —comprising 50-95% by weight of a free radically curable-component, farther comprising at least one (meth)acrylate monomer or oligomer, 5-49% by weight of a cationically curable component, further comprising a cycloaliphatic epoxide, an oxetane mixture, containing a monooxetane compound and a polyoxetane compound, and a thermoplastic polycaprolactone with a molecular weight of 20,000-100,000 g/mol, a free radical photoinitiator, a UV blocker, a cationic photoinitiator, optionally a cationic photosensitiser, and optionally a thermal initiator, wherein the percent by weight is based on the total weight of the photopolymer' composition. The invention also relates to the use of a photopolymer composition according to the present invention for producing a three-dimensional object through additive manufacturing and to a three-dimensional object obtained through additive manufacturing using the photopolymer composition—according the present invention.
US11130873B2 Multifunctional polymeric photoinitiators
The present invention relates to novel compounds based on 3-ketocoumarins, which are useful as photoinitiators and sensitizer and to compositions thereof. More particularly, the novel compounds comprise a polyhydroxy polymeric core, which is chemically bonded to 3-ketocoumarin derivatives.
US11130872B2 Red paint for ceramic decoration
The present invention provides a red paint for ceramic decoration, including a glass matrix, and a red colorant and a protective material that are intermingled in the glass matrix. The red colorant contains gold nanoparticles and silver nanoparticles. The protective material contains silica nanoparticles.
US11130869B2 Aqueous copolymer coating compositions for industrial and construction applications
Copolymer dispersions containing polyamide segments in aqueous media form binders for coatings for various industrial and construction materials. The copolymers have a high percentage of amide linkages. The copolymers are linked into higher molecular weight species by reactions with polyisocyanates (which forms urea linkages if the other reactant is an amine or a urethane linkage if the other reactant is a hydroxyl group).
US11130867B2 Curable compositions containing 1,1-di-activated vinyl compounds and related coatings and processes
Curable compositions comprising 1,1-di-activated vinyl compounds are provided herein. Also provided are coatings formed from 1,1-di-activated vinyl compounds. Also provided are processes for coating substrates and articles. Curable compositions including 1,1-di-activated vinyl compounds that function as crosslinking agents are described.
US11130865B2 Rhodamine dyes and conjugates
The present invention relates generally to novel rhodamine dyes which upon conjugation with another molecule form single isomeric conjugation products. These novel rhodamine dyes contain only one single functional group on the rhodomine molecule for conjugation so that their conjugation products are single isomeric conjugation products.
US11130860B2 Thermoplastic composite
A thermoplastic composite comprising a thermoplastic polymer matrix comprising an amorphous polyester containing 1,4: 3,6-dianhydrohexitol units, an alicyclic diol and terephthalic acid, wherein diol component comprises 1,4:3,6-dianhydrohexitol and alicyclic diol in ratio from 0.32 to 0.75; and thermoplastic fibers comprising a semi-crystalline polyester containing 1,4: 3,6-dianhydrohexitol units, an alicyclic diol and terephthalic acid, wherein diol component comprises 1,4:3,6-dianhydrohexitol and alicyclic diol in ratio from 0.05 to 0.30 are disclosed. Methods for producing the polymer composite are also disclosed.
US11130858B2 Curable compositions for cured-in-place pipes
Disclosed is a curable composition with enhanced curing time at ambient temperatures, the curable composition including (a) a resin, e.g., 4,4′-isopropylidenediphenol-epichlorohydrin copolymer and (b) one or more curing agents, wherein a ratio of a weight percentage of the resin to a weight percentage of the curing agent or curing agents is from about 12:1 to about 15:1. Also disclosed is a method of curing a cured-in-place liner, wherein the cured-in-place liner contains the above curable composition.
US11130857B2 Epoxy resin composition, prepreg, and fiber-reinforced composite material
The present invention provides an epoxy resin composition that serves to produce a cured epoxy resin that simultaneously realizes a high heat resistance, a high elastic modulus, and a low color and to produce a molded article having a good appearance without suffering the formation of white spots on the surface thereof when used as matrix resin in a fiber reinforced composite material. The epoxy resin composition includes an epoxy resin as component [A], an aromatic urea [B1] and/or an imidazole compound [B2] as component [B], and a borate ester compound as component [C], containing dicyandiamide in the amount of 0.5 part by mass or less relative to the total quantity of epoxy resins which accounts for 100 parts by mass, wherein the epoxy resin composition meets certain sets of further requirements with respect to its composition.
US11130853B2 Polypropylene composite resin composition including silyated microfibrillated cellulose and vehicle pillar trim using the same
The present invention relates to a cellulose-containing polypropylene composite resin which is environmentally friendly, and can reduce emission of carbon dioxide and contribute to improvement in fuel efficiency, based on reduced vehicle weight, and a vehicle thin film pillar trim including the same.
US11130849B2 Moisture resistant coating for barrier films
A process for making a barrier film having a substrate, a base polymer layer applied to the substrate, an oxide layer applied to the base polymer layer, and a top coat polymer layer applied to the oxide layer is provided. An optional inorganic layer can be applied over the top coat polymer layer. The top coat polymer layer is formed by vapor depositing and curing cyclic aza-silane and acrylate monomer. The use of a silane co-deposited with an acrylate to form the top coat layer of the barrier films provide for enhanced resistance to moisture and improved peel strength adhesion of the top coat layer to the underlying barrier stack layers.
US11130848B2 Laminated optical film and touch panel
An optical layered film includes at least one A layer including a thermoplastic resin [A] and a B layer formed of a thermoplastic resin [B], wherein the at least one A layer is provided on at least one of surfaces of the B layer, a thickness-direction retardation Rthb of the B layer satisfies the following formula (1), and a tensile elongation at break Sa of a 1.5 mm-thick film (a1) formed of the thermoplastic resin [A] satisfies the following formula (2): (1) |Rthb|≤40 nm, and (2) Sa≥100%.
US11130847B2 Externally activated shape changing device
The present invention provides a 4D printed component that uses the photoisomerization stimulus as a method of activation. Other 4D printing methods use heat, moisture, a combination of heat and stress, and the heat from a light source as methods of activation. The present invention takes advantage of 3D printing capability and adds the capability of providing a printable material that dynamically changes shape over time when exposed to an external stimulus. The invention reduces the number of required 3D printed parts to create a moving object. This characteristic reduces the amount of onboard weight of the 3D printed components by reducing the number of parts required to create motion. The present invention removes the need for onboard sensors, processors, motors, power storage, etc. This characteristic will allow for manufacturing of, inter alia, novel medical devices, automated actuators, packaging, smart textiles, etc.
US11130846B2 Aqueous emulsions containing ethylene-vinyl acetate copolymers, preparation process thereof and their use as anti-gelling additives of crude oils
The present invention relates to an aqueous emulsion comprising: a) from 50% to 60% of an organic phase dispersed in an aqueous phase, said organic phase containing a mixture including from 24% to 30%, calculated with respect to the final emulsion, of ethylene-vinyl acetate copolymers and/or polyalkyl(meth)acrylates, indicated in the present description as polymeric component, and a high-boiling organic solvent, or a mixture of said solvents; b) a primary emulsifier at a concentration higher or equal to 0.1% and lower than or equal to 3% by weight, calculated with respect to the final emulsion; c) from 37% to 47% of an aqueous phase; wherein the ratio between said polymer component and said organic solvent in the final aqueous emulsion is at least 1/1 and where the organic solvent and any polymer of the polymeric component have a Hildebrand solubility parameter δ such that, the difference (δsolvent_δpolymer) is lower than 2 in absolute value for any polymer of the polymeric component.
US11130845B2 Thermal interface materials including polymeric phase-change materials
In an embodiment, an article of manufacture includes a first component, a second component, and a thermal interface material. The thermal interface material is disposed between the first component and the second component and includes a polymeric phase-change material. In another embodiment, an article of manufacture includes a first component, a second component, and a thermal interface material disposed between the first component and the second component, the thermal interface material including a polymeric phase-change material, the polymeric phase-change material including a block copolymer formed from a diene, the diene formed from a vinyl-terminated fatty acid monomer having a chemical formula C2H4—R—C(O)OH and an ethylene glycol monomer having a chemical formula C2nH4n+2On+1.
US11130842B2 Process for the preparation of polyether polyols
The invention relates to a method for producing polyether carbonate polyols, wherein (i) in a first step a polyether carbonate polyol is produced from one or more H-functional starter substances, one or more alkylene oxides, and carbon dioxide in the presence of at least one DMC catalyst, and (ii) in a second step the polyether carbonate polyol is chain-extended with a mixture of at least two different alkylene oxides in the presence of at least one DMC catalyst. The invention further relates to polyether carbonate polyols that contain a terminal mixed block of at least two alkylene oxides and to a method for producing soft polyurethane foams, wherein a polyol component containing a polyether carbonate polyol according to the invention is used.
US11130840B2 Aromatic polycarbonate oligomer solid
An aromatic polycarbonate oligomer solid contains a repeating unit represented by formula (1) and a repeating unit represented by formula (2), has a weight average molecular weight of 500 to 10,000, low-molecular-weight components less than or equal to 5.0 area % measured with high-speed liquid chromatography, and a loose bulk density of greater than or equal to 0.25 g/cm3. wherein R1, R2, R3, and R4 are independently a hydrogen atom or an alkyl group with 1 to 4 carbon atoms, and R5 and R6 are independently a hydrogen atom or an alkyl group with 1 to 12 carbon atoms. The aromatic polycarbonate oligomer solid has a substantially reduced amount of low-molecular-weight components, no or a substantially reduced amount of chlorine-containing compounds, high loose bulk density, and ease of handling.
US11130834B2 Polyamide foams which inhibit the spread of fires for filling cavities in mining
Polyamide foams which do not propagate fire are obtained by mixing (i) a liquid isocyanate component which comprises at least one polyisocyanate and in which the molar ratio of aromatic isocyanate groups to the sum of aromatic and aliphatic isocyanate groups is at least 60 mol %, with (ii) at least one liquid isocyanatereactive component which comprises a reactive diluent, and the reactive diluent 10 comprises (a) a chain-extending and/or crosslinking reactive diluent selected from among aliphatic branched C24-66-polycarboxylic acids, alicyclic C24-66-polycarboxylic acids and partial esters of polycarboxylic acids having at least two unesterified carboxyl groups and/or (b) a chain-terminating reactive diluent selected from among aliphatic branched C24-66-monocarboxylic acids, alicyclic C24-66-monocarboxylic acids and partial esters of polycarboxylic acids having one unesterified carboxyl group, wherein the liquid isocyanate-reactive component comprises an aromatic C8-18-polycarboxylic acid and/or an anhydride thereof.
US11130832B2 Modified conjugated diene-based polymer and rubber composition including the same
A modified conjugated diene-based polymer, and more particularly, a modified conjugated diene-based polymer prepared by continuous polymerization and having remarkable processability, narrow molecular weight distribution and excellent physical properties, and a rubber composition including the same.
US11130828B2 Methods for supplying solid catalysts to a solution polymerization reactor
Disclosed is a solution polymerization process, or, alternatively, a method of delivering powder catalysts to a solution polymerization reactor, comprising combining a homogeneous single-site catalyst precursor with α-olefin monomers to form a polyolefin, wherein the homogeneous single-site catalyst precursor is in the form of (i) a dry powder, (ii) suspended in a aliphatic hydrocarbon solvent, or (iii) suspended in an oil or wax, wherein the homogeneous single-site catalyst precursor is at a concentration greater than 0.8 mmole/liter when suspended in the aliphatic hydrocarbon solvent prior to entering the solution polymerization reactor.
US11130827B2 Polyethylene compositions and articles made therefrom
This invention relates to a polyethylene composition, and films therefrom, comprising at least 65 wt % ethylene derived units and from 0.1 to 35 wt % of C3-C12 olefin comonomer derived units, where the polyethylene composition has: a) an RCI,m of less than 85 kg/mol; b) a Tw1−Tw2 value of from −15 to −40° C.; and c) an Mw1/Mw2 value of less than 1.5 where the film has a) a heat seal initiation temperature of X ° C. or less at 5 N of force, where X=0.0015×Y(psi)+62.6 (where Y is the average 1% Secant modulus ((MD+TD)/2)) of the film; b) a dart drop impact of 300 g/mil or more; c) an MD Elmendorf tear of 230 g or more; and d) average 1% Secant modulus ((MD+TD)/2) of 20,000 psi or more.
US11130823B2 Method for producing hydrogels
The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.
US11130819B2 Antibodies
The present invention relates to antibodies binding to 5T4, including bispecific antibodies binding to 5T4 and CD3. The invention further provides pharmaceutical compositions comprising the antibodies and use of the antibodies for therapeutic and diagnostic procedures, in particular in cancer therapy.
US11130817B2 CD73 blocking agents
Provided are antibodies that bind and inhibit CD73, are capable of increasing the proliferation of T cells in the presence of CD39-expressing B cells and ATP. The invention also relates to cells producing such compounds; methods of making such compounds, and antibodies, fragments, variants, and derivatives thereof; pharmaceutical compositions comprising the same; methods of using the compounds to diagnose, treat or prevent cancer.
US11130811B2 ICOS binding proteins
The present invention relates to an ICOS binding protein or antigen binding portion thereof that is an agonist to human ICOS and does not induce complement, ADCC, or CDC when placed in contact with a T cell in vivo and methods of treating cancer, infectious disease and/or sepsis with said ICOS binding protein or antigen binding portion thereof. Further the ICOS binding proteins or antigen binding portions thereof of the present invention are capable of activating a T cell when placed in contact with said T cell; stimulating T cell proliferation when placed in contact with said T cell and/or inducing cytokine production when placed in contact with said T cell. The present invention relates to ICOS binding proteins or antigen binding portions thereof comprising one or more of: SEQ ID NO: 1; SEQ ID NO:2; SEQ ID NO:3; SEQ ID NO:4; SEQ ID NO:5; and/or SEQ ID NO:6.
US11130810B2 Bispecific antibodies specific for PD1 and TIM3
The invention relates to bispecific antibodies comprising a first antigen-binding site that specifically binds to PD1 and a second antigen-binding site that specifically binds to TIM3, in particular to bispecific antibodies, wherein the bispecific antibody binds to 5 TIM3 with a lower binding affinity when compared to the binding to PD1. The invention further relates to methods of producing these molecules and to methods of using the same.
US11130809B2 PD-1 antibody formulation
Provided herein are pharmaceutical formulations for anti-PD-1 antibodies.
US11130807B2 Immunological reagents
This disclosure relates to binding agents with specificity for programmed cell death 1 (PD-1) and to methods for using the same to treat, prevent and/or ameliorate an infectious disease (e.g., human immunodeficiency virus (HIV)), cancer and/or autoimmunity.
US11130801B2 Method for inhibiting platelet derived growth factor signaling with C3aR or C5aR antibodies
A method of modulating growth factor responses of cells expressing C3a receptor (C3aR) and C5a receptor (C5aR) and at least one growth factor receptor includes administering to the cells at least one agent that modulates C3aR and/or C5aR signaling of the cells.
US11130799B2 Cartilage replacement compositions and methods
Described are compositions and methods for cartilage replacement. Also described are collagen scaffolds comprising the composition described herein.
US11130797B2 Covalent modification of biological macromolecules
The present disclosure provides a method of covalently modifying a biological macromolecule, the method comprising subjecting a reaction mixture comprising: (a) a biological macromolecule comprising one or more thiol groups; and (b) a molecule comprising one or more olefin or alkyne moieties to a radical reaction under conditions sufficient to produce the covalently modified biological macromolecule. The present disclosure also provides a method of covalently modifying a biological macromolecule, the method comprising subjecting a reaction mixture comprising: (a) a molecule comprising one or more thiol groups; and (b) a biological macromolecule comprising one or more olefin or alkyne moieties to a radical reaction under conditions sufficient to produce the covalently modified biological macromolecule. The present disclosure further provides a covalently modified biological macromolecule prepared by any of the disclosed methods. The covalently modified biological macromolecules may be further crosslinked to form a scaffold.
US11130792B2 Methods for inhibiting hematopoietic tumor cells with diphtheria tokin-interleukin-3 conjugates
The present invention provides methods for inhibiting interleukin-3 receptor-expressing cells, and, in particular, inhibiting the growth of such cells by using a diphtheria toxin-human interleukin-3 conjugate (DT-IL3) that is toxic to cells expressing the interleukin-3 receptor. In preferred embodiments, the DT-IL3 conjugate is a fusion protein comprising amino acids 1-388 of diphtheria toxin fused via a peptide linker to full-length, human interleukin-3. In certain embodiments, the methods of the present invention relate to the administration of a DT-IL3 conjugate to inhibit the growth of cancer cells and/or cancer stem cells in humans, which cells express one or more subunits of the interleukin-3 receptor. Exemplary cells include myeloid leukemia cancer stem cells. In other embodiments, the methods of the present invention relate to ex vivo purging of bone marrow or peripheral blood to remove cells that express one or more subunits of the interleukin-3 receptor such that the purged bone marrow or peripheral blood is suitable, e.g., for autologous stem cell transplantation to restore hematopoietic function.
US11130789B2 Urine markers for detection of bladder cancer
Early detection of tumors is a major determinant of survival of patients suffering from tumors, including bladder tumors. Members of the BTM or UBTM family can be highly and consistently accumulated in bladder tumor tissue and other tumor tissue, and/or can be accumulated in urine of patients, and thus are markers for bladder and other types of cancer. In certain embodiments, BTMs or UBTMs can accumulate in the urine, and detection of UBTM family members can be an effective diagnostic approach. In some embodiments, quantitative PCR methods have advantages over microarray methods. In other embodiments, detection and quantification of a plurality of BTMs or UBTMs can increase the sensitivity and specificity of detection of bladder cancer, and therefore provides methods for determining the stage and type of bladder cancer. Kits provide easy, convenient ways for carrying out the methods of this invention.
US11130788B2 Modified bacterial microcompartment shell proteins
The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair.
US11130783B2 CD40 targeted peptides and uses thereof
The present disclosure is related to compositions comprising peptides that bind CD40 and methods of use in inhibiting interaction of CD40 and CD154 and inducing immunosuppression. Provided herein are methods of transplantation and methods of inhibiting donor specific immune response. Also provided herein are methods of treatment for autoimmune diseases, inflammatory diseases and cancer.
US11130780B2 Inhibitors of growth factor activation enzymes
The present invention generally relates to compounds that are useful for inhibiting one or more of hepatocyte growth factor activator, matriptase, hepsin, Factor Xa, or thrombin. The present invention also relates to various methods of using the inhibitor compounds including treating a malignancy, a pre-malignant condition, or cancer by administering an effective amount of the inhibitor to a subject in need thereof.
US11130779B2 PPAR agonists and methods of use thereof
Provided herein are deuterated compounds and compositions useful in increasing PPARδ activity. The compounds have a formula where L5 comprises at least one deuterium. Exemplary species include The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
US11130773B2 STING agonistic compound
A drug or agent containing a compound having an agonistic activity to STING as an active ingredient, where the compound is represented by the following general formula (I-1): wherein all symbols represent the same meanings as described in the specification, and the compound can be used as an active ingredient of an agent for suppressing the progression of, suppressing the recurrence of and/or treating cancer or infectious disease.
US11130772B2 CYP-eicosanoid derivatives
The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.
US11130769B2 Spiro-sulfonamide derivatives as inhibitors of myeloid cell leukemia-1 (MCL-1) protein
The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I as well as methods of their use and preparation, are also described.
US11130768B2 Bicyclic pyrazole derivatives
The present invention covers bicyclic pyrazole compounds of general formula (I): in which G, A, R1, R2, R3, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.
US11130766B2 Deuterated thienopiperidine derivatives, manufacturing method, and application thereof
The present invention discloses deuterated thienopiperidine derivatives, a manufacturing method and an application thereof. The deuterated thienopiperidine derivatives in the present invention are of a structure of the following formula (I). The present invention also comprises the application of the deuterated thienopiperidine derivatives as a drug for treating and preventing cardiovascular and cerebrovascular diseases.
US11130763B2 Method for preparing a bicyclic guanidine and its derivatives
The present invention relates to a method of producing a bicyclic guanidine and its derivatives. In particular, the present invention relates to a method of producing triazabicyclodecene (TBD) and its derivatives, particularly alkyl derivatives, such as methyl triazabicyclodecene (MTBD), and MTBD-derived ionic liquids. The invention also relates to the use of said compounds in cellulose dissolution and subsequent processing.
US11130761B2 Substituted pyrrolo[2,1-f][1,2,4]triazines as FGFR inhibitors
Disclosed are an FGFR inhibitor and the use thereof in the preparation of a drug for treating FGFR-related diseases. In particular, disclosed are a compound as shown in formula (I) and a pharmaceutically acceptable salt thereof.
US11130758B2 Tetrahydropyrazolopyrimidine compounds
Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
US11130755B2 Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders
The present invention relates to 8-aryl-substituted and 8-heteroaryl-substituted 9H-pyrido[3,4-b]indoles of the formula (I), in which A, E, G, R1 to R6 and R10 are as defined in the claims, which stimulate chondrogenesis and cartilage matrix synthesis and can be used in the treatment of cartilage disorders and conditions in which a regeneration of damaged cartilage is desired, for example joint diseases such as osteoarthritis. The invention furthermore relates to processes for the synthesis of the compounds of the formula (I), their use as pharmaceuticals, and pharmaceutical compositions comprising them.
US11130751B2 Quinoxaline and pyridopyrazine derivatives as PI3K-beta inhibitors
The present invention relates to substituted quinoxaline and pyridopyrazine derivatives of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as pI3Kβ inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
US11130747B2 Plurality of host materials and an organic electroluminescence device comprising the same
The present invention relates to a plurality of host materials and an organic electroluminescent device comprising the same. By comprising a specific combination of a plurality of host compounds, the organic electroluminescent device according to the present invention provides high efficiency and long lifespan.
US11130746B2 Therapeutic compounds
The present invention relates to compounds that are antagonists of the orexin-1 receptor. The compounds have the structural formula (I) defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity.
US11130744B2 Indenyl compounds, pharmaceutical compositions, and medical uses thereof
Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
US11130741B2 Anti-infective heterocyclic compounds and uses thereof
The present invention relates to heterocyclic compounds of Formula I useful as anti-infective agents. The present invention further relates to a method of treating an infection by administering such compounds, and to pharmaceutical compositions comprising such compounds.
US11130737B2 Multifunctional aminoquinoline therapeutic agents
Aminoquinoline compounds useful for treating chronic pain, addiction, and other conditions are provided. The aminoquinoline compound is represented by Formula (I): in which the substituents thereof are defined as set forth in the specification.
US11130736B2 Human TLR8-selective agonists
The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R1, R2, R3, R4, R5, R6, R7, R8 are defined herein.
US11130735B2 Process for the preparation of fluopicolide
The present invention relates to an improved process for the preparation of substituted pyridylmethyl-benzamide derivatives of formula (I), in particular 2,6-Dichloro-N-{[3-chloro-5-(trifluoromethyl)-2-pyridyl]methyl}benzamide (Fluopicolide), from substituted 2-(Aminomethyl)pyridine derivatives which are obtained by Raney-Nickel hydrogenation.
US11130731B2 Sulfonylureas and related compounds and use of same
The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
US11130729B2 CCL2 inhibitors
Compounds, pharmaceutically acceptable salts, and pharmaceutical compositions thereof are disclosed that are useful for inhibition of the biological activity of CCL2, as well as methods of treatment for diseases involving the biological activity of CCL2.
US11130727B2 Process for the production of methyl acrylate from methyl lactate
The present invention is directed to a process for the production of methyl acrylate wherein methyl lactate is contacted with a ZSM-5 catalyst in the presence of methanol. It was found that the presence of methanol is essential to obtain a selective process with a high yield. With the process according to the invention methyl acrylate may be obtained as the major product of the reaction, especially if methanol is used as solvent instead of water, while acrylic acid is detected in minor quantity (usually below 10 C %, but often below 5 C %). Methanol may be used as the sole solvent in the process, but preferably also a small amount of water is present in the solvent. In one aspect of the invention, between 1 and 25 wt % of water, based on the total amount of solvent is present.
US11130725B2 Methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in hydroformylation processes
The present invention relates to methods for slowing deactivation of a catalyst and/or slowing tetraphosphine ligand usage in a hydroformylation process. In one aspect, a method comprises (a) contacting an olefin with carbon monoxide, hydrogen and a catalyst, the catalyst comprising (A) a transition metal, (B) a tetraphosphine having the structure described herein, and, optionally, (C) a monophosphine having the structure described herein, the contacting conducted in one or more reaction zones and at hydroformylation conditions; and (b) adding additional monophosphine having the structure described herein to a reaction zone.
US11130716B2 Organic slow-acting fertilizer using plantaginis semen husk and manufacturing method therefor
The present invention provides organic slow-acting fertilizer using psyllium seed husk and a method for producing the same. Macroelements or secondary elements selected from 12 essential nutrient elements (N, P, K, Ca, Mg, S, Fe, Mn, Cu, B, Mo, and Zn) for edible plants are extracted from each of oil cake (collectively referring to residue remaining after extraction of vegetable oil, and including soybean oil cake, palm oil cake, etc.), blood meal (livestock blood), dead fish or bonefish-containing by-products, bone meal, Dead Sea mineral, egg shell, seashell, oystershell, natural gypsum, dolomite, phyllite, and natural salt, by a predetermined extraction process, and are impregnated in larger amounts into a porous material such as zeolite, and organic fertilizers are produced in the form of psyllium seed husk-bound grains for more rapid and effective impregnation so that suitable proportions of element fertilizers can be supplied to each type of plant.
US11130712B2 Method of producing polycrystalline Y-358 superconductor
A method of producing polycrystalline Y3Ba5Cu8Oy (Y-358) whereby powders of yttrium (III) oxide, a barium (II) salt, and copper (II) oxide are pelletized, calcined at 850 to 950° C. for 8 to 16 hours, ball milled under controlled conditions, pelletized again and sintered in an oxygen atmosphere at 900 to 1000° C. for up to 72 hours. The polycrystalline Y3Ba5Cu8Oy thus produced is in the form of elongated crystals having an average length of 2 to 10 μm and an average width of 1 to 2 μm, and embedded with spherical nanoparticles of yttrium deficient Y3Ba5Cu8Oy having an average diameter of 5 to 20 nm. The spherical nanoparticles are present as agglomerates having flower-like morphology with an average particles size of 30 to 60 nm. The ball milled polycrystalline Y3Ba5Cu8Oy prepared under controlled conditions shows significant enhancement of superconducting and flux pinning properties.
US11130710B2 Roofing tile and method for producing such a roofing tile
A roofing tile composed of concrete material and a method for producing such a roofing tile. The concrete material contains a binder, a gravel, a light-weight aggregate, and added water. The roofing tile has at least one watercourse and a lateral interlocking joint having a covering fold and a water fold. The ratio of water to binder is less than 0.3, the light-weight aggregate is composed of a material that is hydrophobic and/or not hygroscopic, and the roofing tile has a density in the range of 1.6 g/cm3 to 1.9 g/cm3 after the hardening. The roofing tile has a thickness of 5 mm to 9 mm, preferably 7 mm to 8 mm, in the highly loaded regions, preferably in the region of the watercourse.
US11130705B2 Glass-based articles with improved fracture resistance
Glass-based articles are provided that exhibit improved fracture resistance. The relationships between properties attributable to the glass composition and stress profile of the glass-based articles are provided that indicate improved fracture resistance.
US11130702B2 Optical fiber manufacturing method
Provided is an optical fiber manufacturing method that uses a low-cost large optical fiber preform having high precision. The optical fiber manufacturing method includes at least a positioning step of positioning core rods in a hollow carbon pipe that contains carbon as a main component, a soot preform preparation step of filling a gap between the carbon pipe and the core rods with silica powder that contains SiO2 as a main component, thereby producing a soot preform, a consolidating step of introducing the soot preform into a furnace and consolidating the silica powder, thereby producing a transparent intermediate preform from the soot preform, an extraction step of extracting the transparent intermediate preform from the carbon pipe, and a drawing step of drawing the transparent intermediate preform, thereby manufacturing an optical fiber.
US11130700B2 Feedstock gel and method of making glass-ceramic articles from the feedstock gel
A method of making a glass-ceramic article includes synthesizing a feedstock gel that includes a base oxide network comprising Na2O, CaO, and SiO2, in which a molar ratio of Na2O:CaO:SiO2 in the gel is 1:2:3, and then converting the feedstock gel into a glass-ceramic article such as a container or a partially-formed container. The conversion of the feedstock gel into a glass-ceramic container may be performed at a temperature that does not exceed 900° C. and may include the steps of pressing the feedstock gel into a compressed solid green-body, sintering the green-body into a solid monolithic body of a glass-ceramic material, deforming the solid monolithic glass-ceramic body into a glass-ceramic preform, and cooling the preform. A glass-ceramic article having a glass-ceramic material that has a molar ratio of Na2O:CaO:SiO2 that is 1:2:3 is also disclosed.
US11130697B2 Glass manufacturing method and apparatus
A glass manufacturing method. A plurality of stress values in a glass sheet are determined in a plurality of locations of the glass sheet respectively. A plurality of light leakage degrees are determined in the plurality of locations of a polarization-based display provided with the glass sheet, when the polarization-based display is in a state to block light transmissions. The plurality of determined stress values are modified based on the plurality of determined light leakage degrees. At least one additional glass sheet is manufactured in a glass sheet manufacturing process with at least one process condition of the glass sheet manufacturing process being adjusted based on the plurality of modified stress values.
US11130696B2 Methods for reconditioning glass manufacturing systems
A method for reconditioning a glass manufacturing system includes establishing a reducing atmosphere in a glass melting vessel and draining a glass melt composition from the melting vessel while the reducing atmosphere is in the vessel. The pressure of the reducing atmosphere is greater than the pressure of the atmosphere surrounding the melting vessel and the reducing atmosphere is established by operating at least one combustion burner in the melting vessel in a fuel-rich condition.
US11130693B1 Combination biological contactor and self-backwashing filter systems
A combination biological contactor and self-backwashing filter system for water treatment is disclosed. The system may include a treatment vessel defining an upper chamber and a lower chamber. A biological contactor may be disposed within the upper chamber, and a filter may be disposed in the lower chamber. A contactor outlet conduit and inlet manifold may be used to transfer water from the biological contactor to filter cells within the filter.
US11130691B2 Anti-scaling composition for water systems
Techniques are described for preparing a water filtration composition that includes activated carbon having an ash content of at least 10 wt. % and particles of a solubilizing agent. The solubilizing agent forms a water-soluble complex with cations (e.g., calcium ions). This increases the solubility of calcium ions and other scale-forming ions in water, thus suppressing scale formation on interior surfaces of water processing infrastructure. The activated carbon and the solubilizing agent are processed to have particle sizes in a same range, thus enabling the activated carbon and the solubilizing agent to be thoroughly mixed together.
US11130684B2 Water softening device and method of operating a water softening device
A water softening device includes a filter configured to decrease hardness of a first stream of raw water to produce a second stream of water with decreased hardness, a first sensor that measures an electrical property of the first stream, a second sensor that measures an electrical property of the second stream, and optionally, a third sensor that detects a water flow through the filter, wherein the filter includes an ion exchange resin operated in H+-mode, and the filter is buffered with at least one salt selected from the group of a potassium salt (K+), a sodium salt (Na+) and a lithium salt (Li+).
US11130682B2 Alumina abrasive particles used for automotive finishing compositions
The present disclosure is directed to an alpha alumina powder having a specific surface area, a specific crystallite size, and a specific particle size distribution for use in abrasive polishes, and method of making such powder. The method of making the alpha alumina powder can include calcining an aluminum oxide precursor powder at a temperature of 800-1500° C. and milling the calcined powder to the specific particle size distribution. The alpha alumina powder disclosed herein can quickly enable high removal rate with undiminished aesthetic quality when used in abrasive polishes.
US11130680B2 Co-production of methanol, ammonia and urea
Process for the co-production of methanol and ammonia together with urea production from a hydrocarbon feed without venting to the atmosphere carbon dioxide captured from the methanol or ammonia synthesis gas and without using expensive air separation units and water gas shift. Carbon dioxide removal from flue gas from reforming section to convert partially or fully all ammonia into urea. Synergi of having methanol, ammonia and urea production to produce coating material for the urea production.
US11130678B2 Carbon formation reactor and method of using same
A novel carbon formation reactor for forming carbon from a carbon-bearing fluidic stream, and method of using the same, is described. The reactor uses a catalyst bearing surface placed within a heated zone in a carbon-bearing fluidic stream to form carbon, which can then be removed from the reactor, with the process repeatable to achieve high extraction efficiencies.
US11130676B2 Reactor packing with preferential flow catalyst
The present invention relates to reactor tubes packed with a catalyst system employed to deliberately bias process gas flow toward the hot tube segment and away from the cold segment in order to reduce the circumferential tube temperature variation.
US11130675B2 Flame spray synthesis of nanoparticles of monoclinic Lu203 and dopant
A nanoparticle containing monoclinic lutetium oxide. A method of: dispersing a lutetium salt solution in a stream of oxygen gas to form droplets, and combusting the droplets to form nanoparticles containing lutetium oxide. The combustion occurs at a temperature sufficient to form monoclinic lutetium oxide in the nanoparticles. An article containing lutetium oxide and having an average grain size of at most 10 microns.
US11130667B2 Device and method for filling a container with a filling product
A device for filling a container with a filling product includes a filling valve for influencing the supply of the filling product into the container to be filled, generally during the transport, by means of a container transporting device, of the containers to be filled, a dosing valve for dosing a dosing product from a dosing product reservoir into the filling valve, and a main component reservoir for providing a main component at the filling valve. A dosing product changing device is provided for changing the dosing product in the dosing product reservoir during the filling operation.
US11130666B2 Wine opener with interior threads
The industry-standard corkscrew has numerous flaws resulting in broken corks—even in the hands of a professional. The present invention is a radical departure from the traditional corkscrew apparatus. The opener generally consists of the handle and an internally threaded half-pipe. The half-pipe slides between the cork and the bottle, wherein the series of threads engage the cork. Rotating the handle causes the threads to bore deeper into the neck of the bottle until the handles meets the lip of the bottle, and then lift the cork out of the bottle until it disengages and falls away from the opener. It should be appreciated that the elegance of the opener resides in its simplicity.
US11130664B2 Tilting bucket
A tilting support or work bucket, or apparatus for an aerial lift including a support frame for supporting an operator. The support frame can have a seat for supporting the operator when in an upright position and a chest support having a portion above and forward of the seat for supporting a chest of the operator when in a forwardly downward tilted position while allowing arms of the operator to extend forwardly out of the support frame. A support member can be pivotably mounted to the support frame at a pivot joint that is located at an upper portion of the support frame when the support frame is in the upright position, for pivotably supporting the support frame. An actuator can be included for positionably rotating the support frame relative to the support member about the pivot joint between the upright position and the forwardly downward tilted position. Since the pivot joint is located in the upper portion of the support frame, pivoting of the support frame from the upright position to the forwardly downward tilted position moves a center of gravity of the support frame rearwardly in the direction of the support member.
US11130653B1 Strap winding and storage device
A strap winding a storage device that is configured to store both a strap and a securing device, such as a ratchet, in a convenient and transportable manner.
US11130645B2 Medium transporting device, image reading apparatus, and recording apparatus
A medium transporting device includes a driving roller that transports a medium and that is driven to rotate, a driven roller that nips the medium between the driving roller and the driven roller and rotates in accordance with the rotation of the driving roller, a rotary shaft of the driven roller, a first pressing member that presses the rotary shaft in a direction in which the driven roller comes into contact with the driving roller, a second pressing member that presses the rotary shaft in a direction in which the driven roller comes into contact with the driving roller, and a spacer member that is integrally provided with a first spacer interposed between the rotary shaft and the first pressing member and a second spacer interposed between the rotary shaft and the second pressing member.
US11130639B2 Modular pulley for continuous belt conveyor system
A modular pulley assembly for a continuous belt conveyor can be assembly from a plurality of modular pulley disks that can be axially aligned and abut against each other to provide pulleys of differing lengths per demand. The modular pulley disks can be made from a non-metallic material such as a polymer and can manufactured by a suitable molding process. Making the modular pulley disks from non-metallic materials enables the disks to be formed with structural geometries such that the assembled pulley is structurally more rigid and can better distribute torsional loads and momentum from the belt to the support shaft.
US11130637B2 Roller transmission for mesh traction
The present invention refers to a conveyor belt comprising a drive roller with a constant section cylinder and conical tip teeth, a mesh type drive belt, wherein said holes coincide with the teeth of the drive roller and a sliding plate, the drive belt being supported on the sliding plate.Wherein coupling between the drive belt and the teeth allows reducing longitudinal and transversal strain of the mesh type drive belt.
US11130635B2 Event seating delivery system
A sub-seating delivery system for event seating venues. The sub-seating system may include a transfer system between a sub-seating conveyor belt and a lower base conveyor belt associated with a plurality of vendors who place orders thereon. The transfer system may incorporate a lift assembly that elevates orders from the base conveyor belt to a relevant sub-seating conveyor belt passing directly under a row of event seating. A delivery robot may be adapted to move an order from the sub-seating conveyor belt to a sub-seating container under a destination seat along the row of event seating. From the sub-seating container, a seated individual may access their ordered items without leaving their seat from which they electronically placed the order.
US11130634B1 Rejection chute for a conveyor system
A rejection chute for a conveyor system, which receives and redirects rejected parcels, includes: a conduit defined by a plurality of side walls; a door; and an actuator operably connected to the door. The conduit includes an enclosed upper portion defining a first opening for receiving parcels into the rejection chute and a lower portion defining a second opening for discharging parcels from the rejection chute. The door is mounted proximate to the first opening and is configured to transition between a first position to cover the first opening and a second position to uncover the first opening. The rejection chute can be integrated into a walking surface alongside of a conveyor to receive and redirect parcels transferred off of the conveyor to a location below the walking surface. An enclosure can be combined with the rejection chute to regulate access and guide parcels into the rejection chute.
US11130627B2 Receptacle liner
A receptacle liner for gripping the receptacle and method of making. A liner may be formed by one or more panels including at least one resilient segment extending from a bottom to a top of the liner. The liner segment can be coextruded so that the resilient segment is made from resilient material and other portions of the liner are made from another material that is less resilient. When the liner is placed in a receptacle, the liner can be expanded by resiliently stretching the resilient segment so that the liner may apply a gripping force to the receptacle. The liner can include gusseted side panels. A mouth can be formed as a recess in the top ends of front and rear panels and extend through the gusseted side panels to define handle portions and form apertures in the handle portions that open to the mouth.
US11130626B2 Systems and processes for space management of three dimensional containers including weight measurements
Systems and methods for remote monitoring of a container are disclosed. The system includes at least one data collector configured to collect data corresponding to a physical attribute of the container, a wireless transmitter in communication with the at least one data collector and configured to transmit the data corresponding to a physical attribute of the container to a location remote from the location of the container, a server in communication with the wireless transmitter to receive and process the data corresponding to a physical attribute of the container, and a physical attribute analysis engine in communication with the server to receive the data corresponding to a physical attribute of the container and calculate a current value for the physical attribute based upon the received data.
US11130624B2 Array of sanitary tissue products
An array of toilet tissue products. A first toilet tissue product can exhibit a first lint value and a total dry tensile strength of greater than 600 g/in, and a second toilet tissue product can exhibit a second lint value which is at least 20% greater than the first lint value and a total dry tensile strength of less than 600 g/in. The first toilet tissue product can be housed within a first toilet tissue product package and the second toilet tissue product can be housed within a second toilet tissue product package. The packages can be designed to be sold individually and wherein the first and second toilet tissue product packages each comprise a common brand name.
US11130623B2 Valve for a container
A valve for a container for dispensing pressurized fluid includes a housing which is mounted on a valve cup, a hollow stem provided in a passage of the housing which stem has at least one lateral inlet opening at its lower end and an outlet opening at its upper end, and a spring. The housing has a circumferential step-like contour with an outer, lower part and a central, upper part. The valve cup follows essentially the step-like contour line of the housing and ends horizontally on the top of the housing close to the stem and a sealing is provided on the upper side of the housing between the housing and the valve cup and which seals at the same time the valve cup against the housing and the stem against the housing.
US11130622B2 Thermally insulated shipping container with layered articulating vacuum insulated panels
A kit from which a thermally insulated shipping container may be assembled and a thermally insulated shipping container assembled from such a kit. The kit includes an outer shell and four flat stock vacuum insulated panels, each with three articulating sections foldable to form 3-dimensional C-shaped units. The panels are nestable pairs effective for lining a lower portion of the outer shell with a first nested pair and lining an upper portion of the outer shell with a second nested pair so as to form a fully enclosed insulated payload chamber within the outer shell.
US11130616B2 Apparatus for closing a container
Various embodiments of the present disclosure provide an apparatus attachable to a container and usable to secure the container closed. The apparatus is transitionable from a nonuse configuration to a use configuration to form an (at least partially) elastic loop attached to the container and usable to circumscribe the container to secure the container closed.
US11130615B2 Envelope-shaped pocket in gift bag
A gift bag having an envelope-shaped pocket therein for transporting and presenting an envelope, card, or other merchandise with the gift bag is provided. The pocket may be integrally formed with the gift bag, or at least partially formed from a separately attached piece, and may be positioned at various locations within the bag. The pocket may also be formed to look like an envelope.
US11130614B2 Stackable container
The invention relates to a stackable container including a holding body, which has a bottom and a lateral wall, which bound a holding chamber. The holding body has stacking elements, which can be moved from a first position (P1) to a second position (P2) and which alternatively allow at least two such stackable containers to be stacked one inside the other and to be stacked one on the other. The holding body also has at least one drain opening in the region of the bottom of the holding body, and the bottom is designed to hold moisture and/or liquid present in the holding chamber and to guide the moisture and/or liquid toward the at least one drain opening. At least one of the stacking elements has a drain groove, which is designed to hold and to lead away moisture and/or liquid.
US11130613B2 Container adapter
An adapter has a circular body having an outer diameter and a height, a counter-bore concentric with the outer diameter, implemented in a lower extremity of the body, having a first inner diameter from the lowest point of the body to an internal horizontal shoulder, a through bore having a second inner diameter concentric with the outer diameter from an upper extremity of the body to the level of the internal horizontal shoulder, a male thread implemented at the upper extremity of the body adapted to engage a female thread of a commercially-available herb grinder, and a course female thread implemented in the counter-bore from the lower extremity of the body to the internal horizontal shoulder, the course female thread of a form to intimately engage threads under a rim of a regular-mouth Mason jar.
US11130612B1 Pallet display assembly
An apparatus for displaying palleted items arranged on a stack of pallets includes a generally flat main panel under the palleted items, having flaps with the palleted items positioned along fold lines, and with separable side panels configured to engage the flaps at the fold lines. When folded away from the palleted items and engaged together, the side panels securely hide the stack of multiple pallets under the palleted items, and present printed sides for advertising.
US11130611B2 Self-contained continuous carton system with self erecting stacking shoulders
A self-contained continuous PDQ package system is provided for shipment and display of products. The PDQ package includes four adjacent sections of preferably corrugated material each with an inner facing and an outer facing surface, with a cut out within the bottom flap panel. Within the cut out, there is a section where an adhesive is placed adhering the inner facing portion of body panel and the inner facing of a section of bottom of the outer panel flap and adjacent mid-section panel. The self-contained continuous PDQ package system also provides an erectable reinforced shoulder to facilitate display of products in a stack of cartons.
US11130610B2 Merchandise storage and display mount
A merchandise storage and display mount includes a support that fits within a recess of the merchandise to be stored and displayed. The merchandise can be a five-sided protective case for a hand-held electronic device. The case defines an recess that receives a portion of the mount. The mount is formed from a foldable material and can be erected from a flat blank by folding the material and gluing at selected locations. The mount includes stiffeners that add durability to the mount. The mount is durable and can be used in combination with different merchandise storage devices.
US11130609B2 Blank for forming disposable cup and disposable cup
A blank 10 for forming a disposable cup, the blank including a cardboard sheet designed to be formed into a body of a cup, the blank including an edge 12 in a form of a first arc for forming the bottom edge of the cup, and a folding line for forming the rim of the cup, wherein the folding line for forming the rim of the cup contains a first folding line 14 formed by a plurality of interconnected arc-shaped folding lines 16 each arcing to the opposite direction than the first arc, and wherein a foldable wing 18 extends form each arc-shaped folding line, the wings being configured to be folded towards the center of the formed cup to lock onto each other to form a cover over the opening of the cup. The present application also provides a disposable cup formed from the blank, and a method for preparing a disposable cup.
US11130608B2 Square bottle
A peripheral groove is defined by a bottom surface, an upper side surface, and a lower side surface, and, in at least one of the upper side surface and the lower side surface, a radially outer end edge of an end portion positioned at a circumferential end portion of a panel surface portion is further away in a bottle axis direction from the bottom surface toward an adjacent corner surface portion when viewed from the outside in the radial direction.
US11130596B2 Folded package
The technology described herein generally relates to an automated packaging apparatus and system that packages loose particles into a conical container as well as the final folded packages. More specifically, loose plant matter, such as crumbled dried leaves, are supplied to successive paper cones. The apparatus packs the crumbled leaves into the cones, closes the wide top portion of the cone into a precise shape, and then runs a quality control check to ensure that the final filled cone meets preset specifications.
US11130595B2 Twisted strap for restraining passenger floor loads
A twisted strap transfers loads generated by an aircraft passenger floor from the floor to an aircraft fuselage. The twisted strap may be formed of carbon fiber reinforced plastic, fiberglass reinforced plastic, or metal, such as aluminum, stainless steel, or titanium alloy. The twisted strap has first and second ends configured to be twisted between 40 to 120 degrees relative to the other whenever connected to a seat track and a forward-aft extending fuselage stiffener, respectively. In at least one form, the twisted strap has a length ranging from 15 to 30 inches, a width of 1 to 2 inches, and thickness of 0.1 to 0.5 inch. Each end incorporates apertures for accommodating separate connectors spaced at least four-to six diameters apart along the length of the twisted strap, and the twisted strap is configured to accommodate minimums of 9 G's of force in tension and 1.5 G's in compression.
US11130590B2 Catalytic fuel tank inerting apparatus for aircraft
Fuel tank inerting systems for aircraft are provided. The systems include a fuel tank, a catalytic reactor arranged to receive a first reactant from a first reactant source and a second reactant from a second reactant source to generate an inert gas that is supplied to the fuel tank to fill an ullage space of the fuel tank, a heat exchanger arranged between the catalytic reactor and the fuel tank and configured to at least one of cool and condense an output from the catalytic reactor to separate out the inert gas, and a controller configured to perform a light-off operation of the catalytic reactor by controlling at least one light-off parameter and, after light-off occurs, adjusting the at least one light-off parameter to an operating level, wherein the at least one light-off parameter comprises a space velocity through the catalytic reactor.
US11130589B2 Crash force attenuating fuel system
A fuel system for a rotorcraft is provided. The fuel system comprises a housing, a fuel bladder located within the housing, a first fuel reservoir, and a number of pressure relief valves. The first fuel reservoir is in fluid communication with the fuel bladder and stowed within the housing. The number of pressure relief valves are configured to divert fuel from the fuel bladder into the first fuel reservoir at a predetermined pressure such that the first fuel reservoir expands to reduce forces on the housing during a crash event.
US11130586B2 Lane dividing apparatus
An evacuation system may comprise a packboard, an evacuation slide configured to deploy from the packboard, and a lane dividing apparatus attached to the evacuation slide, the lane dividing apparatus comprising a strap having flexible material. The lane dividing apparatus may be a dual wall lane divider. The lane dividing apparatus may be a single lane dividing apparatus. The lane dividing apparatus may comprise a first patch disposed at a proximal end of the evacuation slide and a second patch disposed at a second end distal to the proximal end. The lane dividing apparatus may extend from the proximal end to the second end. The lane dividing apparatus may be taut upon deployment of the evacuation slide.
US11130585B2 Aerial vehicle
An aerial vehicle includes an airframe, a canopy capable of adjusting a speed of falling during falling, a brake cord having one end connected to the canopy, a wind-up apparatus provided in the airframe and being capable of winding up the other end of the brake cord, a sensor unit that detects a distance to an external object, and a controller that controls an operation of the wind-up apparatus based on a result of detection by the sensor unit. The wind-up apparatus includes a gas generator as a drive source. The controller has the wind-up apparatus operate to wind up the other end of the brake cord by activating the gas generator when the distance detected by the sensor unit is equal to or smaller than a prescribed value.
US11130576B2 Aircraft seat
A vehicle seat includes a seat with a seat pan and a backrest with a backrest bottom edge articulately being disposed adjacent to a seat pan rear edge. The seat pan and the backrest are positionable with respect to one another such that the seat is configurable into at least one of a taxi, takeoff and landing position, a napping position, and a sleeping position. A swivel is disposed beneath the seat. Base tracking also is disposed beneath the seat, permitting the seat to move in a lateral and a longitudinal direction. The seat also includes a first control to lock and unlock movement of the seat in lateral or longitudinal directions and a second control to lock and unlock the swivel. The swivel may be unlocked while movement of the seat in the lateral and the longitudinal direction is locked.
US11130575B2 Slim aircraft monument with deployable workstation
A slim aircraft monument includes a structure installable in an aircraft passenger cabin adjacent to a cabin space (e.g., in front of an otherwise unused exit door). The slim monument has an overall width of not more than four to six inches. The slim monument includes a side door with an external handle, the door deployable into the cabin space to reveal a group of nested interconnected panels within. The nested panels are similarly deployable into the cabin space to form a substantially horizontal work surface and, underneath the work surface, vertically stacked bays providing temporary storage for storage drawers and a cart space adjacent to the storage drawers, the cart space capable of accommodating a half-size galley cart.
US11130573B2 Disbursement system for an unmanned aerial vehicle
A disbursement system for a UAV is provided. The disbursement system may include a plurality of disbursement nozzles operable to dispense an agricultural product at variable flowrates, a flow controller responsive to instructions and operable to regulate a volume of the agricultural product dispensed by the disbursement nozzles, and a control system. The control system may include a plurality of sensors operable to monitor a plurality of flight parameters and a processing unit configured to model an effect of the plurality of flight parameters on first flow control instructions corresponding to a prescription coverage of the agricultural product and calculate and output modulated flow control instructions to the flow controller. The control system may modulate the first control instructions to change a flowrate of one or more of the plurality of disbursement nozzles to achieve an actual coverage of the agricultural product that is closer to the prescription coverage.
US11130569B2 Flying wing aircraft having a two-dimensional thrust array
An unmanned aircraft system having a flying wing orientation includes an airframe having leading and trailing edges, a two-dimensional thrust array coupled to the leading edge, a power system and a flight control system operable to independently control the speed of each propulsion assembly of the two-dimensional thrust array. In the flying wing orientation, the two-dimensional distributed thrust array provides airspeed control responsive to collectively changing the speed of each propulsion assembly, pitch authority responsive to differentially changing the speed of the propulsion assemblies above the airframe relative to the propulsion assemblies below the airframe, roll authority responsive to differentially changing the speed of the propulsion assemblies rotating clockwise relative to the propulsion assemblies rotating counterclockwise and yaw authority responsive to differentially changing the speed of the propulsion assemblies on a port side of the airframe relative to the propulsion assemblies on a starboard side of the airframe.
US11130567B2 Compactly mounted cyclic flight control for rotorcraft
Systems and methods for compactly mounted cyclic flight control for a rotorcraft. One embodiment is an apparatus that includes a stick base assembly coupled with a cyclic stick and configured to rotate with respect to a mounting frame to control a pitch and a roll of the rotorcraft. A cyclic housing is pivotably coupled with the mounting frame for rotation about a pitch axis to control pitch, and coupled with a pitch actuator having a pitch force sensor to measure its resistance to rotation. The cyclic housing supports the stick base assembly for independent rotation of the stick base assembly about a roll axis to control roll, and the stick base assembly couples with a roll actuator having a roll force sensor to measure its resistance to rotation.
US11130566B2 VTOL aircraft using rotors to simulate rigid wing aero dynamics
A vertical take-off and landing aircraft which uses fixed rotors for both VTOL and forward flight operations. The rotors form a synthetic wing and are positioned to achieve a high span efficiency. The rotors are positioned to even out the lift across the span of the synthetic wing. The synthetic wing may also have narrow front and rear airfoils which may provide structural support as well as providing lift during forward flight. The wing rotors are tilted forward and provide some forward propulsion during horizontal flight.
US11130564B2 Strut shrink using accumulator as energy source
Systems and methods for enabling aircraft shock strut shrink are provided. The system may comprise a shock strut comprising a shrink piston, an accumulator comprising a gas piston and a hydraulic chamber, wherein the gas piston is configured to apply gas pressure to the hydraulic chamber, and a first valve in fluid communication with the accumulator. The system may further comprise a second valve, wherein the second valve is in fluid communication with a vent, the pneumatic cylinder, and the gas piston, wherein the first valve is in fluid communication with the hydraulic chamber and the shrink piston.
US11130563B2 Monolithic outboard gear beam support fitting
A breakaway support configured to selectively release an actuator from a fitting and a method of providing the breakaway support. The breakaway support includes a race positioned between the actuator and the fitting. The second end of the actuator is connected to the fitting via a ball joint is positioned within the race. The ball joint permits the actuator to pivot about the ball joint in a vertical plane between a first position and a second position. The breakaway support includes a first knuckle that causes the actuator to release from the fitting when the actuator moves in a first direction beyond the first position. A portion of the fitting or a second knuckle may cause the actuator to release from the fitting when the actuator moves in a second direction beyond the second position. A portion of the actuator may break to release the actuator from the fitting.
US11130555B1 Service door for cowls on outboard marine propulsion devices
A service door for a cowl for an outboard marine propulsion device that includes a door panel that is positionable in an open position and in a closed position. A first hinge rotatably couples the door panel to the cowl. A biasing device operates in conjunction with the first hinge and biases the door panel towards the open position. A second hinge rotatably couples the door panel to the cowl and at least one of the first hinge and the second hinge provides only one shear of rotation between the door panel and the cowl. A damper operates in conjunction with the second hinge and resists rotation of the door panel towards the open position. The inside of the cowl is accessible when the door panel is in the open position and inaccessible when the door panel is in the closed position.
US11130547B2 Systems and methods associated with magnetically activated mechanical binding for pedals
A mechanical binding that is opened and closed via magnetic forces. This may allow for systems to utilize a strong mechanical lock that is activated and deactivated with simple magnetic mechanisms, allowing for a simple and compact design.
US11130545B2 Bicycle control device and bicycle suspension system including bicycle control device
A bicycle control device is provided for a bicycle that includes a front wheel, a drive train and a suspension. The drive train includes an input unit to which driving force is input, a rear wheel to which the driving force is transmitted, and a transmission mechanism that transmits the driving force that is input to input unit to the rear wheel. The bicycle control device includes an electronic controller that changes an operation state of the suspension in accordance with movement of at least one of the input unit, the transmission mechanism, the front wheel and the rear wheel in a state in which the rear wheel is not rotated by the driving force that is input to the input unit.
US11130541B2 Saddle type vehicle
A saddle type vehicle includes two front wheels, a left front wheel supporting member and a right front wheel supporting member which are turned around a left front wheel turning axis and a right front wheel turning axis respectively, an upper lean arm and a lower lean arm which are rotated around an axis perpendicular to a vehicle width direction, and a steering rod. The upper arm is connected to the left and right members via first and second connecting parts which are provided on the left front wheel turning axis. The lower arm is connected to the left and right members via third and fourth connecting parts which are provided on the right front wheel turning axis. The steering rod is arranged forward of the steering spindle. In a front view of the vehicle body, the steering rod is arranged between the upper and lower arms.
US11130535B1 User configurable trailer
Methods, systems, and apparatus, including computer programs encoded on computer storage media, coordinate dynamic adjustments of a trailer based in part on a user profile associated with a user physically present at the trailer and an activity profile associated with an activity selected to be performed at the trailer. A dynamic adjustment may modify a tilt of a lower surface of the trailer. A dynamic adjustment may modify a dimension(s) of the trailer based in part on a detected object(s). Various dynamic adjustments may occur concurrently, individually and/or sequentially. The trailer may be a moveable trailer for temporary attachment with a vehicle.
US11130534B2 Self-propelled trailer
A self-propelled trailer is provided and includes a frame, a pair of rear drive wheels, a steerable wheel, a drive system, a platform and a lifting device. The frame forms an undercarriage chassis upon which the pair of rear drive wheels and steerable wheel secured to an undercarriage chassis along opposite ends thereof. The drive system includes a power system connected to the pair of rear drive wheels and a control system connected to the steerable wheel. The platform is positioned above and secured to the undercarriage chassis, and includes a planar deck and a subframe extending upward from the undercarriage chassis and spacing the planar deck therefrom. The lifting device is secured to the undercarriage chassis and positioned between the steerable wheel and the pair of rear drive wheels with respect to a length of the frame, and includes a crane extending upward from the frame.
US11130530B2 Load-bearing structural
Load-bearing structural component (1) in particular of a motor vehicle including a strut-dome (2) to hold the strut and an engine support (3) to fasten an engine wherein the load-bearing structural component (1) is formed in one-piece as a single part.
US11130529B2 Vehicle body rear structure
A vehicle body rear structure includes: a rear wheel well disposed inside a vehicle body and extending in a longitudinal direction of the vehicle body; a rear pillar disposed rearward of the rear wheel well and extending in an upper-lower direction of the vehicle body; and a rear panel joined to the rear pillar and extending in the upper-lower direction. The rear pillar includes a pillar inner and a pillar outer disposed rearward of the pillar inner in the longitudinal direction of the vehicle body. The rear panel has a joint portion, at which the rear panel and the pillar inner are joined together, and the pillar outer has an opening at a position rearward of the joint portion in the longitudinal direction of the vehicle body.
US11130523B2 Driving supporter
A driving supporter includes a support inhibitor that inhibits support of driving when a steering-operation value is greater than a threshold value. The support inhibitor includes a threshold-value determiner that determines the threshold value to a value greater when a first object and a second object are present than when the first object is present, and the second object is absent. The first object has a relationship in which a relative positional relationship between the object and an own vehicle is a relationship in which a steering operation is estimated to be performed in a first direction in which the own vehicle avoids the object. The second object has a relationship in which the relative positional relationship is a relationship in which the steering operation is estimated to be performed in a second direction reverse to the first direction such that the own vehicle avoids the object.
US11130522B2 Lane departure prevention apparatus
A lane departure prevention apparatus includes a driving support ECU configured to perform a lane departure prevention control. The driving support ECU performs the lane departure prevention control with vibrating a steering wheel when determining that a control performing condition becomes satisfied and a traveling lane is straight. The control performing condition becomes satisfied when a vehicle has a high probability of departing from the traveling lane. The driving support ECU performs the lane departure control without vibrating the steering wheel at least in a case where the vehicle has a high probability of departing from the traveling lane toward an outer side of the curved lane.
US11130521B2 Steering control unit
A steering angle calculation circuit of an ECU includes a neutral point calculation circuit, a correction amount calculation circuit, an adder, and an absolute angle calculation circuit. When started, the neutral point calculation circuit calculates a motor neutral point from a steering angle detected through a steering sensor and a motor rotation angle detected through a relative angle sensor. The correction amount calculation circuit calculates a correction angle that is a difference between a conversion value and an actual value of the motor rotation angle with respect to the steering angle. The conversion value is obtained by converting the steering angle in terms of the motor rotation angle by taking into account a theoretical specific stroke. The adder calculates a final motor neutral point by adding the correction angle calculated by the correction amount calculation circuit to the motor neutral point calculated by the neutral point calculation circuit.
US11130515B2 Cover assembly, motor and electric steering device including same
One embodiment relates to a cover assembly, a motor and an electric steering device including the same, the cover assembly comprising: a disc-shaped cover body; and a plurality of first holes formed at the cover body, wherein a grommet is disposed in the first hole, and the grommet is formed to extend and protrude from the upper surface of the cover body. Therefore, the cover assembly can stably guide the arrangement of the motor coils since the grommet is formed to be integrated with the cover body such that the first holes formed at the cover body are extended.
US11130513B2 Cart adapted for connection to a wheelchair
A cart for connecting or attaching to a wheelchair is provided to assist a wheelchair user to more easily collect and move items, such as groceries. In certain embodiments the cart is further defined as a shopping cart.
US11130511B2 Light weight pick cart
Various configurations of light weight pick carts are disclosed; some embodiments may alternate between a first configuration having two shelf racks and a second configuration having both a shelf rack and a flatbed. A first shelf rack has multiple accessory support units attached, having multiple different configurations to facilitate holding differing shapes, sizes, or weights of accessories. Swivel casters and multiple handle locations can enhance maneuverability; and proper selection of material and use of perforation and wire frames may reduce weight to ease operation. For stability, a removable second shelf rack may engage the first shelf rack using hooks, while a removable flatbed unit may engage the first shelf rack using notches. The second shelf rack provides more discrete storage locations, while the flatbed permits transportation of larger or heavier items. This versatility enhances the utility of the cart.
US11130509B2 System and method for detecting a break in a railway track
The present invention refers to a method for detecting a break in a railway track, system for detecting a break in a railway track (1) and device for detecting a break in a railway track (500), in which a first track (101) and a second track (102) are connected defining measuring sections (302, 303) and electrical detection networks (M1, M2), in which a device for detecting a break in a railway track (500) is coupled to said tracks (101, 102) and arranged to measure at least one electrical parameter of at least one electrical detection network (M1, M2) and selectively promote an output (502) that indicates a state of at least one track (101, 102).
US11130506B2 Rail vehicle
The present invention provides a rail vehicle. The rail vehicle includes: an underframe assembly, a side wall assembly, a vehicle roof assembly, and a vehicle end assembly. The underframe assembly includes a primary energy absorption structure and an underframe edge beam which are connected. The primary energy absorption structure has at least two energy absorbing cavities that are set at interval. The lower end of the side wall assembly is connected with the underframe assembly. The upper end of the side wall assembly is connected with the vehicle roof assembly. The vehicle end assembly includes an end energy absorption structure whose lower end is connected with the primary energy absorption structure, and upper end is connected with the vehicle roof assembly. By using the technical solution of the present invention, that is, the primary energy absorption structure of the underframe assembly, the vehicle roof assembly, and the end energy absorption structure which is installed between the vehicle roof assembly and the primary energy absorption structure form the overall energy absorbing structure at the end of the vehicle body structure, there is no need to add an independent energy absorbing component. The present invention improves impact energy absorbing performance of the vehicle without increasing the overall dimension of the vehicle body structure.
US11130501B2 System, method and apparatus for controlling autonomous driving vehicle
The present disclosure discloses a system, method and apparatus for controlling an autonomous driving vehicle. A specific embodiment of the method comprises: periodically sending a heartbeat signal and/or communication data to a master control terminal device to determine whether the master control terminal device fails; and in response to determining a failure of the master control terminal device, acquiring data collected by a standby sensor, analyzing the data to generate a control instruction, and sending the generated control instruction to an electronic controller to enable the electronic controller to control the autonomous driving vehicle. The implementation improves the reliability of the autonomous driving vehicle.
US11130498B2 Motor vehicle
A motor vehicle sets a front wheel average rotation speed that is an average rotation speed of left and right front wheels, based on a rotation speed of a first motor, and sets a rear wheel average rotation speed that is an average rotation speed of left and right rear wheels, based on a rotation speed of a second motor. When a difference between the front wheel average rotation speed and the rear wheel average rotation speed is larger than a first reference value, the motor vehicle sets a vehicle body speed, based on the lower between the front wheel average rotation speed and the rear wheel average rotation speed. The motor vehicle compares a difference between the vehicle body speed and the wheel speed of each wheel, with a second reference value and thereby determines whether the wheel idles.
US11130497B2 Method and system for ensemble vehicle control prediction in autonomous driving vehicles
The present teaching relates to method, system, medium, and implementation of human-like vehicle control for an autonomous vehicle. Recorded human driving data are first received, which include vehicle state data, vehicle control data, and environment data. For each piece of recorded human driving data, a vehicle kinematic model based vehicle control signal is generated in accordance with a vehicle kinematic model based on a corresponding vehicle state and vehicle control data of the piece of recorded human driving data. A human-like vehicle control model is obtained, via machine learning, based on the recorded human driving data as well as the vehicle kinematic model based vehicle control signal generated based on vehicle kinematic model. Such derived human-like vehicle control model is to be used to generate a human-like vehicle control signal with respect to a target motion of an autonomous vehicle to achieve human-like vehicle control behavior.
US11130491B2 Protection device for a drivetrain of a motor vehicle
A protection device for a drivetrain of a motor vehicle having an engine and an automatic transmission, with at least one hydraulic converter. In order to protect the drivetrain, the protection device has a sensor device and a control device. The sensor device is designed to detect a rolling movement of the motor vehicle counter to the selected direction of travel of an engaged gearspeed of the automatic transmission, and the control device is designed to control a brake system of the motor vehicle as a function of the detected rolling movement, in order to limit a rolling speed of the motor vehicle counter to the selected direction of travel to a maximum speed.
US11130490B2 Vehicle control device
After stop control and before start control, if a situation monitoring unit does not detect predetermined change of a peripheral situation or a host vehicle situation, a travel control unit performs the start control at the normal control amount, and if the situation monitoring unit detects the predetermined change of the peripheral situation or the host vehicle situation, the travel control unit performs the start control at the control amount that is suppressed compared with the normal control amount.
US11130489B2 Driving mode switching device
A driving mode switching device includes a determination section, a notification section, a detection section, and a control section. The determination section is configured to determine whether a state has occurred in which automatic driving needs to be terminated. The notification section is configured to notify a driver of the instruction for performing a switching operation as a predetermined operation of a vehicle in the case of determining, by the determination section, that the state has occurred in which the automatic driving needs to be terminated. The detection section is configured to detect the switching operation. The control section is configured to switch travelling from automatic driving to manual driving in the case of detecting the switching operation by the detection section.
US11130486B2 Limp-home control method for hybrid vehicle
A limp-home control method for a hybrid vehicle may include: a fault determination step for determining, by a controller, whether a solenoid valve battery short circuit fault occurs in a transmission; a first limp-home step for controlling, by the controller, solenoid valves to implement a limp-home gear stage while maintaining a state where power is suppliable to the solenoid valves involved in shifting gears when it is determined that the solenoid valve battery short circuit fault exists; an engine necessity verification step for verifying, by the controller, whether engagement of an engine clutch is needed; and a second limp-home step for driving, by the controller, a solenoid valve controlling the engine clutch to engage the engine clutch, implementing limp-home driving by engine power when the engagement of the engine clutch is needed.
US11130485B2 Systems and methods for improving vehicle driveline operation
Systems and methods for improving operation of a hybrid vehicle driveline are presented. In one example, pressures applied to two different clutches are coordinated such that a pressure boost phase of a driveline disconnect clutch does not occur at a same time as a pressure boost phase of a transmission shifting clutch.
US11130484B2 Control device and control method for hybrid vehicle
A control device for a hybrid vehicle calculates a required drive force based on an accelerator position. The control device also calculates a required torque of the engine based on the required drive force. The control device further calculates a target torque for the engine by subjecting the required torque to a gradual change process for lessening a change in a value and performs an engine control such that an engine torque becomes equal to the target torque. The control device also performs a torque control on the motor such that a drive force of the hybrid vehicle becomes equal to the required drive force in a state in which the engine torque is equal to the target torque.
US11130482B2 Brake chamber stroke sensor
A brake chamber includes a chamber housing having an end, a push rod configured for reciprocal movement in the chamber housing in a first direction and a second direction over a stroke distance, a return spring disposed in the chamber housing configured to urge the push rod in the second direction and a sensor assembly having a sensor and a magnet movable relative to the sensor with movement of the push rod. The sensor is configured to detect a magnetic field strength of the magnet and output sensor data representative of the detected magnetic field strength. The sensor assembly is configured to determine a position of the push rod based on the sensor data over the entire stroke distance.
US11130481B2 Method for electronically controlling a pneumatic braking system in a vehicle, and electronically controllable pneumatic braking system
A method for electronically controlling a pneumatic brake system in a vehicle includes determining that a failure or a defect has occurred in electronic actuation of wheel brakes of the pneumatic brake system, and electronically actuating a pilot valve via a redundancy signal in response to determining that the failure or the defect in the electronic actuation has occurred so as to actuate the wheel brakes in a redundant electropneumatic manner. The redundancy signal is specified in such a manner that the pilot valve alternately turns for a pulse time into a second switch position and for a pause time into a first switch position. The pilot valve outputs, as a pilot pressure, a low pressure level in the first switch position and a high pressure level in the second switch position. The wheel brakes are actuated using a service brake braking pressure that is dependent upon the pilot pressure.
US11130474B2 End piece for a wiper blade
The invention relates to a terminal end piece (8) for a wiper blade. The terminal end piece (8) comprises a peripheral wall (20) which separates an external environment of the terminal end piece (8) from an internal space (11) of the terminal end piece (8). The terminal end piece (8) delimits a first housing (21) which is arranged in the internal space (11) and which extends primarily in a first plane (P1). A second housing (22) is interposed between the peripheral wall (20) and the first housing (21). The terminal end piece (8) comprises at least one locking member (37) which is configured to connect the terminal end piece (8) to a flexible support (6) of the wiper blade (1). The locking member (37) extends at least from the peripheral wall (20) and comprises a stop (46) which is at least partially arranged in the first housing (21), the locking member (37) being configured so that the stop (46) can be displaced in a second plane (P2) transverse to the first plane (P1) when the first end (31) is introduced into the first housing (21).
US11130471B2 Fingerprint recognition vehicle control method and apparatus
A fingerprint recognition vehicle control apparatus according to an embodiment of the present invention includes: a display unit including a hemispherical display, optical fibers provided in the display and connected to the display through one end of the optical fibers, and a light source connected to the other ends of the optical fibers; a fingerprint recognition unit including a fingerprint recognition sensor and a fingerprint pattern light source provided in the display unit; a gearshift including a physical wheel for operating gear stages and indicators indicating gear states; and a controller operating on the basis of information received from the display unit, the fingerprint recognition unit and the gearshift.
US11130468B2 Airbag apparatus with an active vent mechanism
An active vent mechanism for an airbag apparatus that includes a first vent hole formed in an airbag and a patch capable of releasing and closing the first vent hole. A portion of the patch is coupled to the outer surface of the airbag. The airbag apparatus includes a coupling member having one end coupled to the patch and the other end entering the airbag and coupled to the airbag. A portion of the patch or a portion of the coupling member penetrates through an opening in the vicinity of the first vent hole. The airbag apparatus includes a substantially cylindrical regulating member into which the coupling member is inserted inside the airbag. The regulating member has a first end coupled to the inner surface of the airbag so as to surround the opening inside the airbag and a second end coupled to the coupling member in a sealed state.
US11130465B2 Airbag inflator mounting slots
Airbag modules comprising inflator mounting openings and/or slots. Some embodiments may comprise a cover having an inflator coupled thereto and may further comprise a fastener used to couple the inflator with the housing. A mounting opening may be configured to receive the fastener, wherein the mounting opening is configured to allow material defining the mounting opening to flex during installation of the fastener to reduce a force required to advance the fastener through the mounting opening. The mounting opening may be further configured to resist withdrawal of the fastener after being fully seated in the mounting opening such that a greater amount of force is required to withdraw the fastener from the mounting opening than is required to advance the fastener through the mounting opening.
US11130462B2 Airbag module, steering wheel and method for connecting an airbag module to a steering wheel
The invention relates to an airbag module for arranging on a steering wheel, a locking element and a contact element being arranged on the airbag module. The locking element can be moved and can adopt an unlocked state, a locked state and an intermediate state between the two, in relation to a catch element. In the intermediate state, in which there is mechanical contact between the locking element and the catch element, there is no electrical contact between the contact element and the locking element. In the locked state, in which the locking element is mechanically coupled to the catch element, there is electrical contact between the contact element and the locking element. In the locked state, when the catch element and the locking element are locked together, the contact element, the locking element and the catch element are electrically interconnected.
US11130461B2 Collision activated radio-frequency identification recorder
A collision activated RFID recorder for a vehicle having an RFID reader/recorder, the RFID reader/recorder has a transceiver. A transceiver has a receiver capable of receiving signals and a transmitter capable of sending signals. A collision activated RFID reader/recorder is in electrical communication with memory. Imported data may be stored in the memory of the activated RFID reader/recorder. The collision activated RFID reader/recorder has a collision sensor configured to be mounted on a vehicle. The collision sensor has an antenna configured to transmit an activation signal to the transceiver of the RFID reader/recorder, whereby, said collision sensor detects a collision, generates said activation signal, and then transmits the activation signal to the transceiver of said radio-frequency identification recorder. The RFID reader/recorder is configured to be activated when the transceiver of the RFID reader/recorder receives the activation signal from the collision sensor.
US11130456B2 Low pressure generator for gas turbine engine
A gas turbine engine and methods of operation include a low pressure electric motor-generator arranged for selective operation in a generator mode to generate electrical power or a drive mode to assist rotation of a low pressure drive shaft of the engine.
US11130455B2 Vehicle security enhancement
This disclosure describes systems, methods, and devices related to vehicle security enhancement. For example, a vehicle may receive a plurality of data values from an onboard diagnostic system (OBD) of a vehicle, wherein a first data value is received from a first sensor of the vehicle and a second data value is received from a second sensor of the vehicle. The vehicle may determine a third data value received from a controller area network (CAN) bus of the vehicle. The vehicle may determine the third data value is associated with a false message originating from a device external to the vehicle based on performing a correlation analysis between the first value, the second value and the third value. The vehicle may discard the third data value based on the correlation analysis.
US11130438B2 Propane tank tie down system and method of use
A tank tiedown system for securing a tank during transport in a vehicle. The tank tiedown system comprises a perimeter strap assembly, a first hook-and-loop fastener assembly having a first fastener portion and a second fastener portion, a one or more snap hook assemblies, and one or more ring buckles, the one or more ring buckles comprise at least a second ring buckle. The perimeter strap assembly comprises a first end and a second end. The second ring buckle is attached to the second end of the perimeter strap assembly. The first fastener portion and the second fastener portion are attached to the first end of the perimeter strap assembly with the first fastener portion more proximate to the first end than the second fastener portion.
US11130436B2 Vehicle hauling apparatus
A vehicle hauling apparatus for hauling a second vehicle with a first vehicle includes: a hitch bar for attaching the apparatus to a hitch receiver; a first rail mounted and arranged vertically to the hitch bar; a second rail mounted and arranged to slide vertically along the first rail; a jacking mechanism connecting the first rail to the second rail so as to lift and lower the second rail; a first element of a pivot attached to the second rail; a wheel cradle in which a tire of the second vehicle may be seated; and a second element of the pivot attached to the wheel cradle; whereby the tire of the second vehicle may be rolled along a ground surface into the wheel cradle while the wheel cradle rests on the ground surface and then be raised into a position for hauling by the jacking mechanism.
US11130434B2 Trunk cooler
A trunk cooler removably connected under a seat of a vehicle, the trunk cooler including a base cooler receptacle to store at least one item therein, a plurality of retractable legs disposed on a bottom surface of the base cooler receptacle to support the base cooler receptacle in response to moving the plurality of retractable legs from being retracted in a first vertical position to at least partially extended in a second vertical position, and a cooling system to inject cold air into an interior portion of the base cooler.
US11130431B2 Band supported headrest
A passenger seat headrest includes a frame and a support band. The frame includes a main portion, a first side wing connected to the main portion, and a second side wing connected to the main portion distal from the first side wing. The support band is connected to the frame and extends from the first side wing to the second side wing.
US11130430B2 Vehicle seat back and method of manufacturing the same
A vehicle seat back may include an integrated suspension structure including a suspension wire and suspension mounting guides coupled to both sides of the suspension wire; and a seat back pad foamed for integrating with the integrated suspension structure in a state in which the integrated suspension structure is inserted into a mold for seat back pad formation.
US11130429B2 Vehicle seat
A vehicle seat includes: a seat main body that includes a seat cushion and a seatback that is connected to a seat rear side end portion of the seat cushion and that is rotatable in a seat front-rear direction with respect to the seat cushion; and a lifter device that moves the seat main body in a seat up-down direction, wherein the seat main body is moved toward a seat upper side by the lifter device in a case in which a reclining angle of the seatback is greater than a predetermined angle and the seat main body is lower than a predetermined height.
US11130426B2 Seatback rotating device
Provided is a seatback rotating device. The seatback rotating device includes an electric motor and an application mechanism. The electric motor generates a rotational force that is used to rotationally displace a seatback of a vehicle seat. The application mechanism enables application of the rotational force to the seatback. The application mechanism has a configuration that enables the seatback to be self-rotatable with gravity applied to the seatback in response to the rotational force being applied to the seatback.
US11130425B2 Actuation mechanism for a longitudinal adjuster, longitudinal adjuster for a vehicle seat, and vehicle seat
An actuation mechanism for a longitudinal adjuster of a vehicle seat may have at least one actuation arm, a trigger lever, and a positioning element which is arranged on the trigger lever and which is pivotally mounted on a free lever end of the trigger lever.
US11130424B2 Vehicle seating assembly having capacitive proximity sensor
A vehicle seating assembly is provided that includes a seat base, a seat back pivotally coupled to the seat base and having a front portion and a rear portion, and an actuator operable to change a position of the seating assembly. The assembly also includes a capacitive proximity sensor located on the seat back and configured to detect a user touch command and a user pressure command, and a controller for receiving the user touch command and pressure command and controlling the actuator to change a position of the seating assembly based on a user input.
US11130423B2 Battery system having multiple accumulator apparatus for a battery-operated electric vehicle and method for utilizing a remaining range of same
A method and a device includes a first accumulator apparatus and a second accumulator apparatus. The device includes a control apparatus that is configured so as, depending on a first state of charge of the first accumulator apparatus and/or on a second state of charge of the second accumulator apparatus, to selectively either operate the first accumulator apparatus and the second accumulator apparatus in a series connection between a first terminal and a second terminal in order to supply power to a vehicle at a first supply voltage, or, in order to supply power to a vehicle by way of the second accumulator apparatus at a second supply voltage, to electrically disconnect the first accumulator apparatus from the first terminal and/or from the second terminal.
US11130421B2 Method for controlling the electrical charging of a group of vehicles
The electrical charging of a group of vehicles electrically connected to an electricity grid is controlled. A central control system responds to a received increase command by performing a power increase operation according to an increase scheme. The increase command stipulates an amount by which the power draw by the group of vehicles needs to be increased. The increase scheme is ascertained by the central control system based on the increase command and specifies a temporary increase in the charging power for the energy store of one or more vehicles of the group. If the charging operation for the energy store of at least one vehicle is altered by the user after reception of the increase command and before or during the power increase operation, the central control system checks whether the parameters of the altered charging operation does not decrease the amount of power according to the increase command.
US11130419B2 Electric vehicle charging system
An electric vehicle charging system includes a charging station for receiving a charging command and a positioning signal and a charging trolley connected to the charging station and provided with a license plate recognition module. The charging trolley receives power from the charging station and charges the electric vehicle, wherein, after receiving the charging command and the positioning signal, the charging station controls the charging trolley to go to a parking space in which the electric vehicle is parked to charge the electric vehicle.
US11130415B2 Methods and apparatus for powering a vehicle
This application is directed to an apparatus for providing electrical charge to a vehicle. The apparatus comprises a driven mass, a generator, a charger, a hardware controller, and a communication circuit. The driven mass rotates in response to a kinetic energy of the vehicle and is coupled to a shaft such that rotation of the driven mass causes the shaft to rotate. The driven mass exists in one of (1) an extended position and (2) a retracted position. The generator generates an electrical output based on a mechanical input coupled to the shaft such that rotation of the shaft causes the mechanical input to rotate. The charger is electrically coupled to the generator and: receives the electrical output, generates a charge output based on the electrical output, and conveys the charge output to the vehicle. The controller controls whether the driven mass is in the extended position or the retracted position in response to a signal received from the communication circuit.
US11130414B2 Utility vehicle with vehicle control module
A utility vehicle includes an electric motor constructed to provide motive power to the utility vehicle; a lithium ion battery pack coupled to the electric motor at a first voltage and operative to provide electrical power at the first voltage to the electric motor for driving the utility vehicle, the lithium ion battery pack including a DC/DC converter constructed to output electrical power at a second voltage; and a vehicle control module (VCM) coupled to the DC/DC converter, constructed to operate at the second voltage and constructed to control at least some operations of the utility vehicle.
US11130411B2 Hybrid powertrain system and method
A hybrid powertrain system and method includes a prime mover driving a generator/motor to produce an AC power output. The AC power output is applied to a rectifier which is controlled to transform the applied AC power to DC power to supply a DC Power bus at a selected voltage and current. An energy storage device is also connected to the DC power bus and the current flow between the energy storage device and the DC power bus is monitored and compared to preselected values and the results of that comparison are used to alter the operation of the rectifier to increase or decrease, as needed, the current provided to the DC power bus as electrical loads on the DC power bus change.
US11130401B2 Hub wheel for tandem axles
A wheel hub for tandem axles including a housing, a reduction system, sun gears, planetary gears and a connection sleeve. The housing contains the reduction system, which is formed by the conical sun gears and the conical planetary gears that are accommodated in a supporting structure. The sun gears are mounted in a yoke that is attached to the supporting structure. The conical planetary gears are attached, respectively, to a differential housing in a fixed way and to an end of a semi-draft having free rotation. The connection sleeve is mounted in the end of the semi-draft having concentric mobility in relation to the conical planetary gear through an actuator system placed in an end of the supporting structure. The connection sleeve is formed by a body having a surface with double connection toothing disclosing a toothing of the yoke, and the toothing of the conical planetary gear.
US11130395B2 Vehicle covering apparatus
The embodiments provide a vehicle covering apparatus and a vehicle cover. The vehicle covering apparatus includes a base, an upright member, an arm, an extension rod a coupler assembly and support line.
US11130394B2 Vehicular window trim assembly and decorative molding assembly for vehicle door frame
A vehicular window trim assembly includes a decorative outer trim member having upper and lower outer boundary mating portions formed on the perimeter of the trim member. The assembly also includes a channel-shaped window seal having a mouth to receive a panel-like member and upper and lower outer boundary mating portions formed on the perimeter of the seal mateable in sealed relationship with the upper and lower outer boundary mating portions, respectively, of the trim member to form an outer boundary. Mating portions of the trim member and the seal are joined together to form an outer boundary.
US11130393B2 Vehicle cargo cover system and related componentry
A vehicle cargo cover system, including a cover frame slider configured to be slidable along a slider axis and a ratchet strap assembly coupled to the cover frame slider. The ratchet strap assembly includes: a ratchet strap pivotably coupled to the cover frame slider about a strap axis generally parallel to the slider axis and a ratchet latch configured to accept the ratchet strap therethrough. The ratchet latch includes: a base, an advancement lever pivotable with respect to the base to advance the ratchet strap, and a releasable pawl movably coupled to the base to releasably latch the ratchet strap with respect to the base, and a hook carried by the base of the ratchet latch.
US11130389B2 Compressor, air conditioning system and vehicle
The present disclosure discloses a compressor, an air conditioning system and a vehicle. The compressor comprises a compression cavity, and further comprises a flash cavity capable of flashing a liquid refrigerant, and a communicating passage that communicates a flash cavity gas outlet of the flash cavity and an enthalpy increasing gas supply port of the compression cavity; the flash cavity is provided with an inlet and a liquid outlet, the inlet of the flash cavity is configured to be communicated with an outlet of a condenser, and the liquid outlet of the flash cavity is configured to be communicated with an inlet of an evaporator. The air conditioning system comprises the compressor, the evaporator, the condenser, a flasher, and various pipelines for connecting the entire system. The compressor comprises the flash cavity with a flash function, so that the entire enthalpy increasing system is simpler, the space for an additional flasher structure is saved, and the enthalpy increasing system is more suitable for a vehicle-mounted air conditioning system with a limited space. The present disclosure also discloses a vehicle, particularly an electric vehicle, using the air conditioning system.
US11130383B2 Roll stabilizer for a motor vehicle
An electromechanical roll stabilizer for a motor vehicle includes a housing, a rotor position sensor board, and an actuator torque sensor board. The housing has a motor unit that has a stator and a rotor integrated therein. The rotor position sensor board and the actuator torque sensor board are arranged between two stabilizer halves. The actuator torque sensor board has a digitization and transmission unit for digitizing the sensed torque and transmitting the digitized torque to a data forwarding module arranged on the rotor position sensor board. The rotor position sensor board has a rotor position detection unit for sensing and digitizing the rotor position and a data processing unit. The sensing of the rotor position can be triggered by at least one command signal of a controller to the rotor position detection unit. The data processing unit is provided to process the sensed measured values.
US11130381B2 Air spring unit with short cardanic fold
An air spring unit for a vehicle is described. The air spring unit forms a rolling fold and a cardanic fold. A type of bellows guidance of the air spring, the cardanic fold begins, at the rolling fold side, below that end of the external guide of the air spring unit which is at the air spring cover side. A cardanic fold of axially short construction is realized which, despite a small axial structural space, has the elasticity of a cardanic fold of tall construction.
US11130377B2 Amphibious vehicle provided with a faired running gear
An amphibious vehicle such as a tug boat, comprising a running gear configured to be at least positioned in a deployed position suited to the rolling of the vehicle, and at least one retracted position suited to the navigation of the vehicle. The running gear comprises a fairing element rigidly connected to the running gear, so that the fairing element advantageously serves as an anti-projection device in the deployed position of the running gear. According to one option, the vehicle comprises a semi-rigid shell.
US11130374B2 Pneumatic tyre with elements for the easy removal of additional layers
Pneumatic tyre (1) comprising a carcass ply (11), two ring beads (12), a tread strip (10), a tread belt (15) comprising at least two tread plies (16), an innerliner (2) and an additional functional material layer (4,5) arranged between the innerliner (2) and the inner cavity (17) of the pneumatic tyre (1), wherein between the innerliner (2) and the layer of additional functional material (4,5) a net layer (3) is interposed, which facilitates the removal thereof during disposal at the end-of-life of the pneumatic tyre.
US11130368B2 Caster
The invention provides a caster comprising a bracket, a first transmission device and two wheels. The two wheels are connected by a transmission screw and are fixed to the bracket. The first transmission device comprises an annular retaining portion and a plurality of first balls, the plurality of first balls are equiangularly arranged in a circumferential direction of the annular retaining portion, and opposite sides of the annular retaining portion are respectively embedded in the respective wheels. The caster of the invention can solve the problems in the prior art that it is difficult to control the gap between the two wheels, the resistance generated between the two wheels is large and noise is easily generated.
US11130360B2 Seal-type thermal transfer image-receiving sheet
Provided is a seal-type thermal transfer image-receiving sheet capable of providing a seal section having novel designability. A seal-type thermal transfer image-receiving sheet includes a release section and a seal section integrated. The seal section is provided peelably from the release section. The seal section has a layered structure in which a pressure-adhesive layer and a receiving layer capable of receiving a sublimable dye are layered in the order mentioned from the side of the release section. When the seal section is peeled off from the release section, a reference plate and the seal section peeled off are superposed together, and a reflection density of the reference plate is measured from the side of the seal section, the value of the reflection density is 15% or more, on the presupposition that the reflection density of the reference plate before the superposition with the seal section is set to 100%.
US11130358B2 Audio data compression
In one example of the disclosure, subject audio data, indicative of a subject audio captured via a transducer during an operation of a subject electromechanical device, is accessed. Baseline audio data, indicative of a baseline audio captured during an operation of a baseline electromechanical device, is accessed. An electronic file that includes differences between the subject audio data and the baseline audio data is created.
US11130353B2 Thermoformable overcoat in roll-to-roll format printers for thermoforming applications
A system for printing at least one stretchable ink on a thermoformable substrate including a first surface and a second surface opposite the first surface. The system includes an unwinder, a printing module and a rewinder. The unwinder is arranged to feed the thermoformable substrate from a first roll into a printing module. The printing module includes a flood coater arranged to deposit a coating layer on the first surface of the thermoformable substrate. The rewinder is arranged to receive the thermoformable substrate and to form the thermoformable substrate into a second roll.
US11130350B2 Application apparatus and image forming system incorporating same
An application apparatus includes a first roller configured to apply a treatment liquid to a recording medium conveyed; and a second roller disposed in contact with the first roller and forming, with the first roller, a conveyance nip in which the recording medium is nipped. The application apparatus further includes a third roller disposed in contact with the first roller at a position different from the conveyance nip, and a fourth roller disposed in contact with the second roller at a position different from the conveyance nip. The third roller has a rigidity higher than a rigidity of the first roller, and the fourth roller has rigidity higher than a rigidity of the second roller.
US11130348B2 Inkjet printer
A printer can comprise an ink head for discharging ink toward a printing medium, and a blowing device for blowing air against the printing medium. The blowing device can comprise a first case that is disposed further rearward, in a direction of movement, than the ink head. The first case can have a first air intake opening for taking in air of the vicinity of the printing medium, a first fan for drawing in air from the first air intake opening and expelling air from a first outlet opening. A second case can be positioned further rearward, in the movement direction Y1, than the first air intake opening, and can have a second air intake opening that opens facing upward and a second fan for drawing in air from the second air intake opening and expelling air toward the printing medium from a second outlet opening. The magnitude of the airflow of the first fan can be less than the magnitude of the airflow of the second fan.
US11130346B2 Combination including carbon powder replenishing bottle and carbon powder storage member
A combination includes a carbon powder replenishing bottle and a carbon powder storage member combined together. The carbon powder replenishing bottle includes: a hollow body storing carbon powder; and a bottle mouth, which is connected to the hollow body and has a stopper portion, wherein the stopper portion restricts a depth, by which the bottle mouth is placed into a carbon powder entrance of the carbon powder storage member, so that the bottle mouth is only partially inserted into the carbon powder entrance to form a hermetic connection with the carbon powder entrance through the stopper portion. The stopper portion is entirely accommodated within an outer housing of the carbon powder storage member, In the carbon powder storage member, a fluid in the housing is discharged through a fluid discharge mechanism when a user performs a refilling operation.
US11130345B2 Liquid ejecting head and liquid ejecting system
A liquid ejecting head has a supply opening toward which a liquid is supplied, a collection opening through which the supplied liquid is collected, a nozzle that ejects the liquid supplied from the supply opening, and a filter disposed at an intermediate point in a flow path that couples the supply opening and the nozzle together. The liquid ejecting head further has a plurality of outlets leading from an upstream chamber disposed upstream of the filter to the collection opening.
US11130339B2 Molded fluid flow structure
In one example, a fluid flow structure includes a micro device embedded in a monolithic molding having a channel therein through which fluid may flow directly to the device.
US11130338B2 Liquid discharge head and liquid discharge apparatus
A liquid discharge head includes a plurality of nozzles from which a liquid is discharged in a discharge direction, a plurality of individual chambers communicating with the plurality of nozzles, respectively, a common chamber communicating with each of the plurality of individual chambers, a drive element configured to change a volume of each of the plurality of individual chambers to discharge the liquid in the plurality of individual chambers from the plurality of nozzles, and a refrigerant channel through which a refrigerant flows, the refrigerant channel facing the common chamber via a partition in the discharge direction.
US11130337B2 Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head includes a first-nozzle-row set in which a pair of first-nozzle-rows is disposed in a second direction intersecting a first direction so that the first-nozzle-rows are symmetrical about a reference line extending in the first direction and a second-nozzle-row set in which a pair of second-nozzle-rows is disposed in the second direction so that the second-nozzle-rows are symmetrical about the reference line. In the second direction, the distance between the second-nozzle-rows is longer than the distance between the first-nozzle-rows. First nozzles constituting the first-nozzle-row set communicate with a first liquid supply source via a first supply flow path. Second nozzles constituting the second-nozzle-row set communicate with a second liquid supply source via a second supply flow path. Compliance capacity of the second supply flow path is larger than compliance capacity of the first supply flow path.
US11130335B2 Piezoelectric thin-film element, liquid discharge head, head module, liquid discharge device, liquid discharge apparatus, and method for manufacturing piezoelectric thin-film element
A piezoelectric thin-film element includes a diaphragm plate on a substrate; a lower electrode on the diaphragm plate; a piezoelectric film on the lower electrode, the piezoelectric film containing Pb; and an upper electrode on the piezoelectric film. The diaphragm plate is a laminate in which a silicon oxide layer, a silicon nitride layer, and an amorphous layer containing a metal oxide to trap Pb of the piezoelectric film are laminated in turn on the substrate. The amorphous layer has a thickness of preventing Pb of the piezoelectric film from reaching the silicon nitride layer.
US11130333B2 Inkjet head and inkjet recording apparatus
Provided is an inkjet head including: ink discharge sections with pressure chambers, nozzles, and first individual ink ejection flow paths and second individual ink ejection flow paths; a first common ink ejection flow path which communicates to the first individual ink ejection flow paths and into which ink flows through the first individual ink ejection flow paths in a first flow-in section; and a second common ink ejection flow path which communicates to the second individual ink ejection flow paths and into which ink flows through the second individual ink ejection flow paths in a second flow-in section. As a position of the nozzles is nearer to a one end, corresponding positions at which ink ejected from the ink end respectively in the first flow-in section and the second flow-in section. A first direction of ejection of ink in the first flow-in section of the first common ink ejection flow path has a component opposite to a second direction of ejection of ink in the second flow-in section of the second common ink ejection flow path.
US11130332B2 Head unit and liquid discharging apparatus
A head unit comprising: a first line through which a driving signal is supplied; a first discharging section that has a first piezoelectric element having a first electrode, the first discharging section discharging liquid according to the displacement of the first piezoelectric element, the displacement being caused when the driving signal is supplied to the first electrode; a detection circuit that detects the potential of a second line; a first switch that makes a switchover as to whether to electrically couple the first electrode and first line together; a second switch that makes a switchover as to whether to electrically couple the first electrode and second line together; a third switch that makes a switchover as to whether to electrically couple the first line and second line together; and a first resistor provided in series with the third switch between the first line and the second line.
US11130331B2 Printing apparatus
According to the invention there is an apparatus for printing onto cylindrical structures comprising: a plurality of inker devices each comprising a print cylinder and one or more servomotors for adjustably controlling the position or orientation of a print cylinder; a blanket device comprising a plurality of print blankets, in which the blanket device is configured to bring each print blanket into contact with the print cylinders to transfer ink from the print cylinders to the print blanket, and to bring each print blanket into contact with a cylindrical structure to achieve printing thereon; a transporter for transporting the cylindrical structures into and out of contact with the print blankets; and an automatic print correction system comprising a print inspection device for detecting a misregistration of ink transferred from one or more of the print cylinders onto a print blanket, and a controller for controlling the servomotors of the print cylinders to correct the misregistration in response to data received from the print inspection device.
US11130330B2 Multiple printing plate mounting system
The multiple printing plate mounting system of the present disclosure may be used to mount multiple flexible printing plates simultaneously onto a printing sleeve. The system has a back rotary vacuum plate with a plurality of distinct vacuum zones and may be controlled via valve by a computer control system. A filler plate may also be controlled with the same vacuum patterns. The filler plate will move minutely side-to-side. A front plate with match-controlled vacuum patterns may also have a servo to control front-to-back-movement. The distinct vacuum zones are used together with the movable front, back, and filler vacuum plates to selectively, individually, and independently align the flexible printing plates prior to mounting.
US11130326B2 Wrappable protective sleeve with closure and locating feature and methods of construction and use thereof
A wrappable protective sleeve for providing protection to at least one elongate member contained therein and methods of construction and use thereof are provided. The sleeve includes a flexible textile wall having opposite inner and outer faces bounded by opposite edges and opposite ends. The opposite edges extend generally parallel to one another between the opposite ends. A pair of adhesive layers is bonded to the inner face, with each of the adhesive layers being spaced from one another. The adhesive layers extend between the opposite ends adjacent the opposite edges. Further, a release paper is releasably adhered to the pair of adhesive layers for subsequent removal and use of the sleeve.
US11130323B2 Moldable polyester sheet materials and recyclable barrier packages made therefrom
Moldable sheet materials include a first layer including a first polyester, a second layer including a second polyester, and, optionally, a third layer including a third polyester. The first polyester, the second polyester, and the third polyester are the same as or different from each other of the first polyester, the second polyester, and the third polyester. The sheet materials exclude one or more of adhesives, ethylene vinyl alcohol, polyvinyl alcohol, polyvinylidene chloride, polyamides, polyolefins, polystyrenes, and the like. Molded packages made from the sheet materials exhibit desirable oxygen and water vapor barrier properties while also being suitable for recycling in a polyethylene terephthalate recycle stream.
US11130321B2 Multi-layer composite material containing special copolycarbonates as a matrix material
The present invention relates to a composite material comprising one or more fibre layers of a fibre material, and a silicon-containing copolycarbonate as matrix material. The fibre layer(s) is/are embedded in the matrix material. The present invention further relates to a process for producing these composite materials and to the use thereof for production of construction or housing parts, and to the construction or housing parts themselves.
US11130319B2 Multilayer article suitable for use as a fumigation barrier
A multilayer article (such as a film) suitable for use as a fumigation barrier, the multilayer article comprising at least one an ethylene vinyl alcohol (EVOH) based barrier layer formed from a resin composition predominantly comprising an EVOH component of one or more specific types of ethylene-vinyl alcohol copolymers as described herein.
US11130317B2 Hybrid underlayment for non textile floor covering
A hybrid underlayment including a compliant material layer and a rigid material layer affixed to the compliant material layer. The compliant material layer exhibits a compression deflection as measured according to ASTM standard D-1056-14 in the range of from about 0.14 kilogram force per square centimeter to about 1.76 kilogram force per square centimeter, and a thickness of at least about 2 millimeters. The rigid material layer exhibits a thickness of at least about 0.5 millimeters and a flexural modulus of at least about 600 MPa and flexural strength of at least about 35 MPa in both the length and width directions, both flexural modulus and flexural strength as measured according to ASTM D790-17.
US11130315B2 Heat ray shielding fine particles, heat ray shielding fine particle dispersion liquid, heat ray shielding film, heat ray shielding glass, heat ray shielding dispersion body, and heat ray shielding laminated transparent substrate
Heat ray shielding fine particles, heat ray shielding fine particle dispersion liquid, heat ray shielding film, heat ray shielding glass, heat ray shielding dispersion body, and heat ray shielding laminated transparent substrate that exhibit heat ray shielding properties and suppress scorching sensation on skin when employed in window materials and the like, also enable usage of communication devices, imaging devices, sensors, etc. that employ near-infrared light across these structures. The particles are composite tungsten oxide fine particles having a heat ray shielding function; and when a visible light transmittance is 85% when computed for light absorption by the particles alone, the average value of transmittance in the wavelength region from 800 nm to 900 nm is 30%-60%, and the average value of transmittance in the wavelength region from 1200 nm to 1500 nm is 20% or lower, and the transmittance at a wavelength of 2100 nm is 22% or lower.
US11130312B2 Electrical wire and wire harness using the same
An electrical wire includes an aluminum element wire that has an aluminum base material and carbon nanotubes dispersed in the aluminum base material, in which the aluminum element wire has an electrical conductivity of 62% IACS or more and a tensile strength of 130 MPa or more. The aluminum base material is a polycrystal having a plurality of aluminum crystal grains. Further, a carbon nanotube conductive path, which is composed of the carbon nanotube, and forms a conductive path allowing electricity to conduct therethrough in a longitudinal direction of the aluminum element wire by being present in a part of grain boundaries between the plurality of aluminum crystal grains in a transverse cross section of the aluminum base material, and being present along the longitudinal direction of the aluminum element wire, is formed in the aluminum base material.
US11130311B2 Vapor deposition film, black metallic product, vehicle interior/exterior member, container, and casing
Provided are a vapor deposition film, a black metallic product, a vehicle interior/exterior member, a container, and a casing, which are capable of expressing a jet black metallic design having a luxurious appearance on items of various dimensions by a method simpler than a case of applying black plating and are excellent in physical properties such as light resistance. The vapor deposition film comprises: a protection layer; a decoration layer; and a vapor deposition layer, wherein the vapor deposition layer includes a metal including at least any one of indium and tin, wherein the decoration layer includes a resin and a black pigment, and wherein the black pigment includes carbon black and manganese ferrite having a spinel structure ((Fe,Mn)(Fe,Mn)2O4).
US11130304B2 Thorn assembly for seed oil press
A low speed seed oil expeller press with the capability of extracting oil through a new seed compression design that eliminates the need for filtration, and maintains the captured seed oil at a temperature below 130 degrees F. It has a seed preheating capability and controls the pressure and extraction oil temperature by adjustments of the expeller speed, the head volume and the size of the pressed seed exit orifice in the thorn. The seed oil expeller press eliminates seed rotation within the head volume so as to eliminate crushing, grinding or tearing of the seed by a symmetrical knived press head. The seed oil expeller press regulates seed temperature, seed feed rate, seed pressure, seed rotation and extracted seed oil temperature so as to compensate for the seed size, seed hardness and seed oil content.
US11130302B2 Bead core coating method and bead core coating apparatus
A bead core coating method for coating an annular bead core with a belt-shaped rubber sheet including the steps of: winding the rubber sheet extruded on an outer circumferential surface of a rotary drum; sticking a part of the rubber sheet to an outer surface of the bead core which is in rotation; and winding a remaining part of the rubber sheet stuck on the outer surface of the bead core while sequentially sticking the remaining part along the outer surface of the bead core, wherein air is blown to a sheet portion including the end that is not stuck to the outer surface of the bead core in the currently-winding rubber sheet in a first direction toward the end along a sheet surface or a second direction inclined toward an outer surface side of the bead core as compared with the first direction.
US11130298B2 Method for repair of a stiffened panel of isogrid type and stiffened panel of isogrid type thus repaired
A method for repair of a damaged stiffened panel of isogrid type, wherein the repair method comprises a step of removal of material with the aim of removing at least one damaged rib and also steps of fitting at least one structural reinforcement connecting at least two nodes positioned about the damaged zone and of at least one wall reinforcement connecting the wall of the stiffened panel and the structural reinforcement.
US11130295B2 Resin transfer molding systems and control logic for manufacturing fiber-reinforced composite parts
Presented are manufacturing control systems for fabricating composite-material structures, methods for making/operating such systems, and resin transfer molding techniques for ameliorating race-tracking effects in fiber-reinforced polymer panels. A method for forming a composite-material construction includes confirming, via a system electronic control unit (ECU), that a fiber-based preform is placed in a mold cavity and that opposing mold segments of the molding apparatus are sealed together. A filler, such as a compressible bladder, a cluster of spring-biased pins, or a spray-chopped fiber bed, is introduced into a void between the fiber-based preform and a tool face of one mold segment to thereby eliminate an unwanted resin race track. The system ECU commands a resin pump to inject resin through a primary gate of the molding apparatus and into the mold cavity to thereby impregnate the fiber-based preform with the resin. One or more vents operate to evacuate air from the mold.
US11130294B2 Injection molded composite blank and guide
This specification discloses an article of manufacture. The article of manufacture has at least one structural blank and at least one guide. The structural blank has a plurality of oriented fiber plies in a thermoplastic matrix. The guide has a plurality of random dispersed fibers in a thermoplastic matrix. The guide is affixed to the structural blank by injection molding and over molding the guide onto the structural blank. The article of manufacture can take a number of forms for use in industries such as aircraft, automobiles, motorcycles, bicycles, trains or watercraft.
US11130292B2 Estimating physical property of 3D printed parts
Methods, systems, and apparatus, including medium-encoded computer program products, for estimating the physical properties of 3D printed objects that include: obtaining a three dimensional (3D) model of a 3D object to be manufactured by a 3D extrusion printer; obtaining at least a portion of tool path data for the 3D extrusion printer to build the 3D object in accordance with the 3D model; creating unit cell geometry from the at least a portion of tool path data using at least one limitation on one or more unit cells of the unit cell geometry with respect to an aspect of the 3D extrusion printer's build of the 3D object; generating a numerical simulation of one or more microstructural properties of the 3D object to be built using the unit cell geometry; and estimating one or more macroscale properties, of the 3D object to be built, from the numerical simulation.
US11130291B2 Composite-based additive manufacturing (CBAM) use of gravity for excess polymer removal
Apparatus and methods are disclosed for reclaiming unused powder in a composite-based additive manufacturing process. According to aspects of the embodiments, there is provided process and apparatus that use a substrate layer frame inversion mechanism that can flip the substrate over 180 degrees. The excess powder will simply drop into a waste reclaim container for later reuse. An optional mechanical vibrator may be used to completely loosen any remaining powder.
US11130289B2 Device for the generative production of a three-dimensional object
An apparatus for the generative production of a three-dimensional object by successive, selective layer-by-layer solidification of construction material layers of a solidifiable construction material by means of at least one energy beam, comprising at least one device for generating at least one energy beam for selective layer-by-layer solidification of individual construction material layers of a solidifiable construction material, wherein the device is configured to generate an energy beam directed directly onto a construction plane, and an exhaust device which is configured to exhaust non-solidified construction material detached from the construction plane during processing and/or process gases arising during processing, wherein the exhaust device comprises at least one exhaust element through which a suction flow may or does flow, wherein at least one passage opening is formed in the at least one exhaust element for passage of an energy beam generated by the device and directed directly onto the construction plane.
US11130286B2 Three-dimensional manufacturing apparatus, three-dimensional manufactured object producing method, and container for three-dimensional manufacturing apparatus
There is provided a three-dimensional manufacturing apparatus which is characterized by comprising: a container configured to hold a liquid photocurable resin; a base configured to support a solid manufactured object obtained by curing the liquid photocurable resin; a moving unit configured to move the base; and a light source unit configured to irradiate light for curing the liquid photocurable resin. The container comprises a light transmission portion which is provided between the light source unit and the base, and is in contact with the liquid photocurable resin. The three-dimensional manufacturing apparatus further comprises a flow facilitating unit configured to facilitate a flow of the photocurable resin which is in contact with the light transmission portion, the flow being attended by the movement of the base.
US11130282B2 Electrostatic 3-D development apparatus using cold fusing
Layers of build and support material on an intermediate transfer surface are exposed to a solvent using a solvent application station to make the build material tacky, without affecting the support material. Then, the intermediate transfer surface moves past a transfuse station (the transfuse station is positioned to receive the layers after exposure to the solvent) and a platen moves relative to the intermediate transfer surface to contact the platen to one of the layers on the intermediate transfer surface. The intermediate transfer surface transfers a layer of the build material and the support material to the platen each time the platen contacts the layers on the intermediate transfer surface at the transfuse station to successively form a freestanding stack of the layers of build and support material on the platen.
US11130278B2 Print head, method and system for 3D printing having variable discharge rate
The invention relates to a print head (100) for an additive fused deposition modelling method having a thermoplastic construction material, comprising:—at least one inlet (10) for receiving a construction material (11) into the print head;—at least one melt region, for melting the construction material (11), which is arranged downstream of the inlet (10) and is fluidically connected, at least temporarily, to the inlet (10); and—at least one first outlet (30) that is fluidically connected, at least temporarily, to the melt region (20), for discharging melted construction material (12) out of the melt region (29) at a first discharge rate; wherein—the print head (100) also comprises at least one second outlet (40) that is fluidically connected, at least temporarily, to the melt region (20) for discharging melted or non-melted construction material (11, 12) out of the melt region (20) at a second discharge rate; and—the first discharge rate can be influenced by a first discharge rate influencing device (50) for the melted construction material (12).
US11130277B2 Systems, apparatus and methods for cryogenic 3D printing
Systems, apparatus and methods for producing objects with cryogenic 3D printing with controllable micro and macrostructure with potential applications in tissue engineering, drug delivery, and the food industry. The technology can produce complex structures with controlled morphology when the printed 3D object is immersed in a liquid coolant, whose upper surface is maintained at the same level as the highest deposited layer of the object. This ensures that the computer-controlled process of freezing is controlled precisely and already printed frozen layers remain at a constant temperature. The technology controls the temperature, flow rate and volume of the printed fluid emitted by the dispenser that has X-Y positional translation and conditions at the interface between the dispenser and coolant surface. The technology can also control the temperature of the pool of liquid coolant and the vertical position of the printing surface and pool of coolant liquid.
US11130274B2 Filament winding apparatus
A filament winding apparatus includes a working area in which an operator performs an operation to at least one bobbin and/or liner on a conveyance path, an operation area in which a winder is driven, a buffer area between the working area and the operation area in a conveyance direction on the conveyance path, and an outside area that is neither the working area, the operation area, nor the buffer area being provided; and first fixed fences provided at borders between (i) the operation area and the buffer area and (ii) the working area and at the borders between (I) the operation area and the buffer area and (II) the outside area; and a first door provided at a border between the working area and the buffer area, and wherein the buffer area includes an accumulator portion capable of accumulating the at least one bobbin and the liner.
US11130271B2 Blow molding device and blow molding method
A blow molding device including: an injection molding unit manufacturing a bottomed preform made of resin; a blow molding unit; a support part supporting the preform; and a conveying unit conveying the support part to the blow molding unit, wherein the blow molding unit includes: a first mold for performing a first step of subjecting the preform to heat-set blowing at a first temperature; a second mold for performing a second step of blow-molding an intermediate molded article, which has been blow-molded by the heat-set blowing, at a second temperature lower than the first temperature, thereby manufacturing a container; and a movement unit capable of moving the first mold and the second mold relative to the support part so as to perform the first step and the second step continuously.
US11130264B2 Label handling system in an in Mould labelling machine
A transfer device with unrolling device, intended for providing a label handling system in an IML machine (In Mould Labelling) with IML labels. The transfer device comprises at least four holders, which are movable between a first and a second position, wherein the first position has a first predetermined relationship between the four or several holders regarding the distance in the X-direction. The holders are intended for retrieval of IML labels from the unrolling device, which comprises a label web, the length of which extends in the Y-direction, with partially stamped out labels, connected to the web with micro connections. The second position has a second predetermined relationship between the four or several holders regarding distance in the X-direction. The holders are intended to deliver the IML labels to the label handling system. The unrolling device comprises adjustment means to make possible the retrieval of labels in the Y-direction, so that the distance in the Y-direction between delivered labels has a different distance in the Y-direction than between two adjacent labels in the web. Further, a method of providing an IML machine with IML labels.
US11130258B2 System and a method for processing material
A system for processing material, for example recycled material, comprises a compacting device (101) for compacting the material and a treatment device (102) for agglomerating, pelletizing, or nozzle-extruding the compacted material. The compacting device comprises a compacting chamber (103) and a compacting element (104) that is moveable in the compacting chamber to reduce the volume of the compacting chamber so as to compact the material to be delivered to the treatment device. As the material is compacted prior to being agglomerated, pelletized, or nozzle-extruded, supply of the material to the treatment device can be more reliable especially when the material is chopped waste plastic or other fluffy material including much air. Furthermore, efficiency of the agglomeration, pelletizing, or nozzle-extruding is improved because the compacting increases density of the material prior to the agglomeration, pelletizing, or nozzle-extruding process.
US11130256B2 Strong and tough structural wood materials, and methods for fabricating and use thereof
A super strong and tough densified wood structure is formed by subjecting a cellulose-based natural wood material to a chemical treatment that partially removes lignin therefrom. The treated wood retains lumina of the natural wood, with cellulose nanofibers of cell walls being aligned. The treated wood is then pressed in a direction crossing the direction in which the lumina extend, such that the lumina collapse and any residual fluid within the wood is removed. As a result, the cell walls become entangled and hydrogen bonds are formed between adjacent cellulose nanofibers, thereby improving the strength and toughness of the wood among other mechanical properties. By further modifying, manipulating, or machining the densified wood, it can be adapted to various applications.
US11130254B2 Handheld power tool
A sprocket arrangement (5) for a handheld power tool such as a saw, comprising a drive unit configured to rotate a drive shaft and cutting tool configured to be driven by the drive shaft (21) via the sprocket arrangement. The sprocket arrangement (5) comprises a gear (1) and at least one flexible element (6a, 6b) arranged such that the drive shaft (21) in the handheld power tool is resiliently connected to the cutting tool in the handheld power tool. A handheld power tool comprising a drive unit, a drive shaft, driving means, and a sprocket arrangement is also provided.
US11130248B2 Multi-material pivot return for shaving systems
Replaceable shaving assemblies are disclosed that include a blade unit, an interface element configured to removeably connect the blade unit to a handle, on which the blade unit is pivotably mounted, and a return element disposed between the blade unit and interface element. The return element provides resistance during shaving and positions the blade unit in a rest position when not in use.
US11130239B2 Method for automatically generating waypoints for imaging shelves within a store
One variation of a method for automatically generating waypoints for imaging shelves within a store includes: dispatching a robotic system to autonomously generating a map of a floor space within the store; accessing an architectural metaspace defining target locations and addresses of the set of shelving structures within the store; distorting the architectural metaspace into alignment with the map to generate a normalized metaspace representing real locations and addresses of the set of shelving structures in the store; defining a set of waypoints distributed longitudinally along and offset laterally from a first shelving structure represented in the normalized metaspace based on a known position of an optical sensor in the robotic system; and dispatching the robotic system to record optical data while occupying the set of waypoints during an imaging routine.
US11130238B2 Mobile control method, mobile robot and computer storage medium
The present application provides a method for controlling a movement of a mobile robot, a mobile robot and a computer storage medium. The method for controlling a movement of a mobile robot, the mobile robot is provided with an image acquisition device, and the method comprises the following steps: identifying a border line between a first obstacle and a ground from an image captured by the image acquisition device; determining a first relative position between a physical position corresponding to the border line and the mobile robot based on preset physical reference information; and controlling the movement of the mobile robot based on the first relative position. Through the technical solution disclosed in the present application, the localization accuracy of the mobile robot can be improved.
US11130236B2 Robot movement teaching apparatus, robot system, and robot controller
A robot movement teaching apparatus including a movement path extraction unit configured to process time-varying images of a first workpiece and fingers or arms of a human working on the first workpiece, and thereby extract a movement path of the fingers or arms of the human; a mapping generation unit configured to generate a transform function for transformation from the first workpiece to a second workpiece worked on by a robot, based on feature points of the first workpiece and feature points of the second workpiece; and a movement path generation unit configured to generate a movement path of the robot based on the movement path of the fingers or arms of the human extracted by the movement path extraction unit and based on the transform function generated by the mapping generation unit.
US11130225B2 Working device and double-arm type working device
A working device includes: a linear motion unit having three degrees of freedom and obtained by combining three linear motion actuators; and a rotary unit having three degrees of freedom and obtained by combining a plurality of rotating mechanisms each having one or more rotational degrees of freedom. The linear motion unit is mounted on a mount such that a base portion of the linear motion unit is fixed to the mount. A base portion of the rotary unit is fixedly mounted on an output portion of the linear motion unit. End effectors are mounted on both the output portion of the linear motion unit and an output portion of the rotary unit.
US11130220B2 Apparatus and method for installation of door checker
An apparatus for installation of a door checker is provided. The apparatus includes a handle, an actuator coupled to the handle, and a hook member having a first end coupled to the actuator and a second end configured to engage with a bolt-hole of a door checker. The actuator includes a body, a push mechanism coupled to the body, a pin member at least partially disposed within the body and coupled to the push mechanism, and a locking element radially disposed within the pin member.
US11130216B2 Selectively adjustable torque indicating tool
A selectively adjustable torque indicating tool is provided for rotating a mechanical fastener to a predetermined torque setting. The tool includes a pair of supports and a tool bit positioned between the pair of supports and engageable with a mechanical fastener such that when the tool bit, a rotational force is imparted on the mechanical fastener. A spring is coupled to the pair of supports, and operatively coupled to the tool bit. The spring includes a first end portion movable relative to the pair of supports between a neutral position and a torqued position in response to the rotational force being imparted on the mechanical fastener by the tool bit. An adjuster is coupled to the spring to adjust a stiffness of the spring such that movement of the first end portion of the spring from the neutral position to the torqued position corresponds to a predefined rotational force.
US11130215B2 Methods and systems for increasing the efficiency of a remote wrench
Methods and systems for increasing the efficiency of a remote wrench. The remote wrench can include a flexible plate within the tool housing or as part of the housing that is more flexible than the rigid housing in conventional remote wrenches that has been shown to limit efficiency. Additionally, a fixed support and a base can be provided that are collectively capable of being coupled to the remote wrench, preferably at the flexible plate, to increase efficiency. The remote wrench operation is therefore improved by reducing inefficiencies and providing a maximum torque output.
US11130212B2 Infinitely directional translating clamp for welding a fan blade cover
A directional translating clamping device comprises a housing that includes a distal housing end and proximate housing end separated along a central axis, and a housing recess at the proximate housing end and extending along the central axis end. The device also includes a slide located in the housing recess, and the slide comprises a slide recess at a slide proximate end co-axial with the housing recess, and a detent in a radial sidewall of the slide prevents the slide from translating beyond a predetermined axial distance along the central axis. A spring is located in the housing recess and exerts an axial force on the distal end of the slide. A stub shaft extends from the distal end of the housing. A roller ball assembly includes a threaded sidewall that engages with the slide recess to removably and replaceably secure the roller ball assembly to the slide.
US11130207B2 Transport tool used for transporting object
A transport tool capable of carrying out attaching an object to an attachment position while positioning the object in a predetermined positional relationship with the attachment position. The transport tool includes a base, a holding section movably supported by the base in a predetermined direction and configured to hold an object, and a positioning section that is provided to the base and configured to arrange the object held by the holding section in a preparation position having a predetermined positional relationship with the attachment position, the positioning section allowing the execution of an attachment operation of attaching the object, which has been arranged in the preparation position, to the attachment position by movement of the holding section relative to the base.
US11130203B2 Systems and methods for welding electrodes
The invention relates generally to welding and, more specifically, to welding wires for arc welding, such as Gas Metal Arc Welding (GMAW) or Flux Core Arc Welding (FCAW). In one embodiment, a tubular welding wire for joining steel workpieces via arc welding includes a steel sheath disposed around a core. The core includes iron powder, iron titanium powder, silico-manganese powder, iron silicon powder, iron sulfide, graphite, rare earth compound, and a frit. The frit includes a Group I or Group II compound, silicon dioxide, and titanium dioxide. The graphite and the frit together comprise less than 10% of the core by weight.
US11130197B2 Laser brazed component and method therefor
In various examples, a component is for use in an implantable medical device. The component includes a pin including a first material attached to a lead including a second material different from the first material of the pin. At least a portion of the lead includes a channel in which at least a portion of the pin sits, the channel including a channel opening defined at least partially by opposing first and second channel sides extending a channel length. At least a first joint is formed along at least a portion of the first channel side. The first joint includes the second material of the lead deformed to at least partially close the channel opening to retain the pin within the channel to attach the lead to the pin. In some examples, the first material includes molybdenum and the second material includes aluminum.
US11130194B2 Friction stir welding tool member, friction stir welding apparatus using the same, and friction stir welding method
The friction stir welding tool member according to the present invention is made of a ceramic member in which a shoulder portion and a probe portion are integrally formed, wherein a root portion of the probe portion and an end portion of the shoulder portion have a curved surface shape; and the friction stir welding tool member has a ratio (R1/D) of 0.02 or more and 0.20 or less when a curvature radius of the end portion of the shoulder portion is defined as R1 (mm) and an outer diameter of the shoulder portion is defined as D (mm). In addition, the ceramic member is preferably made of a silicon nitride sintered body having a Vickers hardness of 1400 HV1 or more. According to the above-described configuration, a friction stir welding tool member having excellent durability can be provided.
US11130193B2 Friction stir welding tool and friction stir welder
A friction stir welding tool includes a housing and a stir pin. The housing includes a first surface, a housing hole formed in the housing and having a housing hole opening on the first surface, and a discharge hole through which the housing hole is in communication with an outside of the housing. The stir pin includes a pin holder and a pin body. The pin holder has a first end portion and a second end portion. The first end portion is configured to be connected to a rotation spindle. The pin body is provided in the housing hole, is detachably attached to the second end portion, and is rotatable together with the pin holder around the rotation axis. The pin body includes a stir portion that protrudes from the first surface via the housing hole opening.
US11130181B2 Surface-coated cutting tool and method for manufacturing the same
A surface-coated cutting tool includes a substrate and a coating formed on a surface of the substrate, the coating including one or two or more layers, at least one of the layers being an Al-rich layer including hard particles, the hard particle having a sodium chloride type crystal structure, and including a first unit phase in a form of a plurality of lumps and a second unit phase interposed between the lumps of the first unit phase, the first unit phase being composed of a nitride or carbonitride of AlxTi1-x, the first unit phase having an atomic ratio x of Al of 0.7 or more and 0.96 or less, the second unit phase being composed of a nitride or carbonitride of AlyTi1-y, the second unit phase having an atomic ratio y of Al exceeding 0.5 and less than 0.7.
US11130179B2 Method for managing a powder in an additive manufacturing facility comprising a plurality of machines
An additive-manufacturing facility and a method for managing a powder transported to and from additive-manufacturing machines of the facility are provided. According to the method, a volume of feedstock powder is stored, and the machines are automatically fed with powder from the volume of feedstock powder. For each machine, the powder fed to the machine undergoes at least one layering operation during an additive-manufacturing cycle, and excess powder in the layering operation is moved away and conveyed from the machine to the volume of feedstock powder. For each machine, recovered powder, which is derived from cleaning rough components produced by the machine, is reintroduced into the volume of feedstock powder. A same collection circuit is used to convey the excess powder and the recovered powder to the volume of feedstock powder.
US11130178B2 Composite processing machine, machining tool, and composite processing method
A machining tool includes a light irradiator, a cover, and a light blocking filter. The light irradiator is to irradiate a workpiece to process the workpiece. The cover covers the light irradiator and the workpiece in the cover. The light blocking filter is configured to change light transmissivity of the light blocking filter in accordance with light from an inside of the cover, which the light blocking filter receives.
US11130176B2 Techniques for producing SMA materials and powders
Embodiments of the present disclosure provide improved techniques for creating SMA materials and SMA powders. SMA materials and powders formed may be used to form porous structures suitable for applications such as biomaterials, damping applications, actuators, and/or sensors. Embodiments for performing hydriding and dehydriding of SMA wires at low pressure and low temperature are provided. Methods may be used to produce a shape memory alloy (SMA) powder. Such methods may include hydriding a length SMA wire under low pressure for a period of time to produce a length of hydrided SMA wire, crushing the length of hydrided SMA wire to form a hydrided SMA powder, and dehydriding the hydrided SMA powder to form a dehydrided SMA powder.
US11130175B2 Spherical metallic powder blends and methods for manufacturing the same
A method for manufacturing a spherical metallic powder blend using a metallic starting material, the method including steps of grinding the metallic starting material to yield an intermediate powder, spheroidizing the intermediate powder to yield a first spherical powder component, and mixing the first spherical powder component with a second spherical powder component, wherein the first spherical powder component and the second spherical powder component have substantially the same chemical composition.
US11130172B2 Continuous casting method and corresponding apparatus
Method for the continuous casting of a product (P), chosen from billets or blooms, along a curved casting line (18), the method providing to cast a liquid metal (M) in a crystallizer (11) having a tubular cavity (12) with an octagonal cross section.
US11130170B2 Integrated casting core-shell structure for making cast component with novel cooling hole architecture
Integrated core-shell investment casting molds that provide tongue or groove structures corresponding, respectively, to groove or tongue structures in the surface of the turbine blade or stator vane, including in locations that are otherwise inaccessible provide a pathway to restrict cooling flow between turbine blades to the flowpath.
US11130169B2 Use of a feeder insert and method for manufacturing a casting mold having a vertical mold separation
A use of a feeder insert, having a volumetric center of gravity which is offset in relation to the opening axis of the passage opening of said feeder insert, in the manufacture of a casting mold having a vertical mold separation and a feeder insert which for dense feeding of the mold cavity during the casting procedure is attached to the casting mold, is described, wherein the feeder insert is positioned in a prefabricated mold part of the casting mold such that the opening axis of said feeder insert runs below the volumetric center of gravity of the latter.
US11130167B2 Axial thread rolling
The present invention is directed to an axial thread rolling process that utilizes a thread rolling head that includes a clutch, that prevents full disengagement of the clutch during thread rolling, and that reverses the direction of rotation used for thread rolling to escape a threaded workpiece from the thread rolling head.
US11130165B2 Electronic servo powered pilot release mechanism
In a roller-style feed mechanism, a feed roll is opened and closed for the purpose of pilot release using a direct-coupled servo motor as opposed to pneumatic or hydraulic cylinders. The electronically controlled servo motor drives a rotating shaft with eccentric cams that interact with cam followers causing the feed rollers separate for pilot release. The cam followers produce a force sufficient to overcome nip pressure when separating the feed rollers during pilot release. The electronically controlled servo motor is preferably operative to sense the point where the cams contact the cam followers after the upper feed roller is closed on the feed material, and automatically sense resistance to determine where the upper roll begins to lift so as to compensate for different material thicknesses.
US11130161B2 High-strength corrosion-resistant composite chequered iron and manufacturing method therefor
Disclosed are a high-strength corrosion-resistant cladding chequered steel and a manufacturing method therefor. The high-strength corrosion-resistant cladding chequered steel includes a substrate and a chequered cladding layer cladded on the substrate by single-sided or double-sided rolling. The mass percentages of the chemical elements of the substrate are: C: 0.01% to 0.20%, Si: 0.10% to 0.5%, Mn: 0.5% to 2.0%, Al: 0.02% to 0.04%, Ti: 0.005% to 0.018%, Nb: 0.005% to 0.020%, 0
US11130159B2 Scanning probe microscope for cleaning nanostructures
The present invention relates to a scanning probe microscope. The scanning probe microscope can be configured to remove a polymeric material from a surface of a nanostructure. The scanning probe microscope includes a metal coated probe tip and a voltage source. The voltage source can be configured to apply a bias voltage between the probe tip and a sample. The bias voltage can be between 0.5 V and 2 V. The scanning probe microscope further includes a sample positioner configured to position the sample in relation to the probe tip and a system controller configured to control the scanning probe microscope.
US11130151B2 System and method for coating a body
At least a part of at least one body is coated. At least one processor determines a respective resulting coating layer based on simulating moving the respective body at least partially through a coating fluid of a dipping bath along different trajectories. The at least one processor determines a first trajectory out of the different simulated trajectories fulfilling one or more pre-defined conditions and causes at least one drive component for moving the respective body to move the respective body at least partially through the coating fluid of the dipping bath along the first trajectory.
US11130145B2 Adjustable escutcheon assembly
An adjustable escutcheon assembly is provided which can be installed flush against a ceiling, wall, or other surface where a supply pipe exits the ceiling, wall, or surface at various angles. The assembly includes a fitting having a curved bearing surface and an aperture for receiving the supply pipe, a retainer which bears against and is adjustable with respect to the curved bearing surface of the fitting, and an escutcheon plate mountable to the retainer. During installation, the retainer and escutcheon plate can be rotated with respect to the pipe and fitting in order to allow flush installation of the retainer and escutcheon against the ceiling, wall, or surface at a variety of angles.
US11130135B2 Microfluidic system and driving method thereof
A microfluidic system is disclosed, including: a first substrate, a second substrate and a droplet flow channel arranged therebetween; a droplet driving unit configured to drive a droplet to move; a first control circuit electrically connected to the droplet driving unit and configured to input a first driving signal to the droplet driving unit to enable the droplet to move along the predetermined movement trajectory; a droplet detection unit configured to detect the droplet and output a detection signal; a second control circuit electrically connected to the droplet detection unit and configured to receive the detection signal and acquire an actual movement trajectory of the droplet; and a signal adjustment unit configured to compare the actual movement trajectory with the predetermined movement trajectory, and if the actual movement trajectory is different from the predetermined movement trajectory, adjust in real time the first driving signal into a second driving signal.
US11130134B2 Method of performing droplet-based assays
Method of performing a droplet-based assay. The method may include obtaining droplets encapsulated by an immiscible liquid and packed closely together in a monolayer, performing a reaction in the droplets while packed closely together in the monolayer; and collecting data related to an analyte from a plurality of the droplets while the droplets remain closely packed together in the monolayer.
US11130130B2 Fluid flow device
A micro-fluidic flow device and method. The device includes a conduit having an inlet and an outlet distal from the inlet. The conduit further includes a plurality of constrictions each having a reduction in a cross-sectional area of the conduit in a direction from the inlet to the outlet. The constrictions are arranged in series and the reduction in cross-sectional area at each of the constrictions is sufficient to induce extensional flow in a fluid travelling therethrough, such that the maximum strain rate in the extensional flow region is at least 500 s−1.
US11130125B2 Prevention and bubble removal from microfluidic devices
A method for manufacturing a fluidic device is provided. The method comprises providing a capillary, providing a structure having a fluidic channel and an opening, reducing an outer diameter of a portion of the capillary to be smaller than the opening of the structure. Furthermore, the method comprises inserting, at least partly, the portion of the capillary through the opening of the structure into the fluidic channel and applying heat to the structure to expand the inserted portion of the capillary to fit the capillary to the structure.
US11130120B2 Micro-pipette tip for forming micro-droplets
A micro-droplet-emulsifier to generate a micro-droplet-emulsion for application on digital polymerase chain reaction is provided. This device includes a micropipette to hold a dispersed-phase-liquid; a droplet generator that attaches to the micro-pipette and has a plurality of substantially flat micro-channels. The dispersed-phase-liquid is forced through the micro-channels to form micro-droplet-emulsion of dispersed-liquid-phase in the continuous-liquid-phase inside the chamber. The size of the micro-droplets is controlled by the shape and the aspect ratio of the micro-channels, the depth of the micro-channels and the material of the micro-droplet-generator-head that dictates the contact angle of the droplet on the micro-channels.
US11130117B2 Catalytic article comprising combined PGM and OSC
The present disclosure provides catalytic materials and catalytic articles formed therewith. The catalytic materials particularly can include an oxygen storage component comprising a solid solution of at least one platinum group metal and at least one rare earth metal oxide. In one or more embodiments, catalytic materials can include a solid solution of a platinum group metal (e.g., palladium) and a mixed metal oxide (e.g., ceria/zirconia).
US11130116B2 Sulfur-tolerant catalytic system
Disclosed in certain embodiments is a sulfur tolerant catalytic system that includes a catalytic material coated onto a substrate.
US11130111B2 Air-cooled heat exchangers
A plant or refinery may include equipment such as reactors, heaters, heat exchangers, regenerators, separators, or the like. Types of heat exchangers include shell and tube, plate, plate and shell, plate fin, air cooled, wetted-surface air cooled, or the like. Operating methods may impact deterioration in equipment condition, prolong equipment life, extend production operating time, or provide other benefits. Mechanical or digital sensors may be used for monitoring equipment, and sensor data may be programmatically analyzed to identify developing problems. For example, sensors may be used in conjunction with one or more system components to detect and correct maldistribution, cross-leakage, strain, pre-leakage, thermal stresses, fouling, vibration, problems in liquid lifting, conditions that can affect air-cooled exchangers, conditions that can affect a wetted-surface air-cooled heat exchanger, or the like. An operating condition or mode may be adjusted to prolong equipment life or avoid equipment failure.
US11130102B2 Mixer with wireless power transmission
A mixer for mixing and degassing fluids includes a revolution device having a revolution base to be driven for rotation; a first spin device connected to the revolution base of the revolution device; a first barrel connected to the first spin device to be spun by the first spin device; an transmitting coil electrically connected to a power source to generate a time-vary magnetic field; and a receiving coil connected to the revolution base of the revolution device and electrically connected to the first spin device, wherein the receiving coil rotates with the revolution base. The receiving coil receives the power from the time-vary magnetic field of the transmitting coil and produces an electromotive force to be supplied to the first spin device.
US11130094B2 Cyclic amine for selectively removing hydrogen sulphide
The use of an amine of the formula (I) in which the R1 to R5 radicals are each as defined in the description, and an absorbent and a process for removing acidic gases from a fluid stream, especially for selectively removing hydrogen sulfide over carbon dioxide. The invention also relates to particular amines suitable for selective removal of hydrogen sulfide. Absorbents based on amines of the formula (I) have high selectivity, high loading capacity and good regeneration capacity.
US11130092B2 Method for concentrating ozone gas and apparatus for concentrating ozone gas
Provided is method for concentrating ozone gas the method including the steps of: allowing ozone gas to be adsorbed onto the adsorbent by introducing ozone gas-containing raw material mixed gas into an adsorption vessel (20) that houses an adsorbent for adsorbing ozone gas; reducing a pressure in a concentration vessel (30) in a state where the concentration vessel (30) does not communicate with the adsorption vessel (20), the concentration vessel (30) being configured to be connected to the adsorption vessel (20) so as to be interswitchable between a state where the concentration vessel (30) communicates with the adsorption vessel (20) and a state where the concentration vessel does not communicate with the adsorption vessel (20); and introducing concentrated mixed gas including ozone gas with a higher ozone gas concentration than the ozone gas concentration in the raw material mixed gas into the concentration vessel (30) by desorbing the ozone gas adsorbed onto the adsorbent using a pressure difference between the internal pressure of the concentration vessel (30) and an internal pressure of the adsorption vessel (20) in a state where the concentration vessel (30) having a reduced internal pressure communicates with the adsorption vessel (20) that houses the adsorbent onto which the ozone gas is adsorbed, and delivering the desorbed ozone gas into the concentration vessel (30). Also provided is an apparatus (1) for concentrating ozone gas for implementing the method.
US11130091B2 Apparatus and method for solvent recovery from drying process
Method and apparatus for condensing a majority of the solvent in a process gas stream at low temperatures, e.g., below the freezing point of water, ca. −5° C. The gas stream exiting the condenser step may be further processed in one or more emission control devices, such as a single or multi-step series of concentrator devices, such as zeolite concentrator devices. One or more emission control operations can be carried out downstream of the single or multi-step concentrators. The aforementioned condensing process enables the one or more concentrators to operate in a favorable temperature range for removal of 99% or more of VOC, thereby meeting or exceeding strict environmental regulations.
US11130089B2 Waste collection unit with a control system for regulating levels of vacuums being drawn in waste containers
A waste collection unit for collecting waste material. First and second waste containers are supported on a portable cart. A control panel is configured to receive one or more inputs of selectively set vacuum levels in the first and/or second waste containers. A control system controls operation of vacuum regulators based on the input(s) to regulate levels of vacuums being drawn in each of the waste containers. Pressure sensors in communication with the control system may be positioned to monitor pressure in the waste containers. A back up port support on the portable cart may be provided to receive a vacuum line for coupling a vacuum manifold to a remote vacuum source not located on the portable cart. Container lamps may be coupled to the first and/or second waste containers and configured to illuminate the waste material within the waste containers to be viewed through transparent windows.
US11130084B2 Multilayer rotomolded grease trap
A grease trap or solids collector for separating waste from waste water has a tank having a multilayer outer wall made of an outer layer of un-foamed plastic, an intermediate layer of foamed plastic, and an inner layer of unfoamed plastic; an inlet invert in the tank for receiving incoming waste water; and an outlet invert for removing water from the tank. An extension collar made up of segments can be included.
US11130081B2 Filter device
A filter device may include a filter housing and a ring filter element arranged upright in the filter housing in an installed state. The ring filter element may include an upper end disc, a lower end disc, and at least two projecting pins, each of which in the installed state may engage in an associated draining passage. One of the connecting pins may be arranged offset relative to another of the connecting pins by at least 120° in a circumferential direction of the ring filter element.
US11130079B2 Filter insert of a fuel filter, filter insert, and fuel filter
A filter material for a filter insert of a fuel filter for separating solid particles and water droplets from fuel. The filter material comprises a particle filter medium layer through which the fuel flows first during use and at least one coalescer medium layer which lies on the particle filter medium layer on the outflow side. At least one coalescer medium layer is gradient-free in the flow direction with respect to the geometrical structure and/or physical properties and/or chemical properties of the layers. The at least one coalescer medium layer has a thickness measured in the flow direction which is maximally as large as the thickness of the particle filter medium layer measured in the flow direction.
US11130077B2 Composite loop chain
A settling basin of a wastewater treatment system includes a collector chain including chain links having a plurality of side bars, stepped connecting pins configured to join the plurality of side bars and including a first end including a head portion having a cross-sectional area larger than portions of the plurality of side bars through which the stepped connecting pin extends, end caps configured to receive second ends of the stepped connecting pins, and apertures defined in the end caps and second ends of the stepped connecting pins configured to receive a retaining element that holds the end caps in position on the second ends of the stepped connecting pins.
US11130076B2 Oil-gas separators comprising non-concentric fluid channels
Oil-gas separators and methods of using the oil-gas separators are disclosed. An exemplary oil-gas separator comprises a first fluid channel for receiving a well fluid, the first fluid channel having an open proximal end, a sealed distal end, and a plurality of perforations in a distal portion of the first fluid channel's exterior wall for expelling well fluid comprising oil and entrained gas into an annular space between the oil-gas separator and a well casing to produce gas-reduced oil and a second fluid channel for receiving the gas-reduced oil, the second fluid channel having a sealed proximal end, an open distal end for expelling the gas-reduced oil to the Earth's surface, and a plurality of perforations in a proximal portion of the second fluid channel's exterior wall for receiving fluid from the annular space.
US11130072B2 Reactive still and methods of using
A method of batch distilling including providing a first substrate that upon distillation releases vapour having deleterious sulfur compounds, providing an inert still, adding the first substrate to the still, installing at least one first reactive article in the still and subsequently performing a first distillation run on the first substrate, such that the installed at least one first reactive article has a first exposed area that is exposed to the distillate, and collecting a first desired fraction from the first run. The distillation during the collection of the first desired fraction is performed at a rate of less than 5 L/(hr*m2) of collected first fraction per first exposed area. Compatible still and kit are also provided.
US11130071B1 Frisbee with a sinusoidal shape
A frisbee balanced to spin about a central axis has a central portion with a top surface and an opposing bottom surface. The central portion terminates peripherally with a circular rim having a sinusoidal curvature. The central portion conforms to the sinusoidal curvature of the rim forming radial variations of peaks and valleys. Plural sinusoidal cycles of radially directed, convex peaks impart thrust enabling it to float in a chosen direction when thrown and to rotate about its central axis developing lift due to air passing over the generally domed top surface.
US11130070B2 Snowman making apparatus
A snowman making apparatus having a hemispherical bowl element, wherein the bowl element has an open top, and an aperture at a base of the bowl element to facilitate collection of snow in the bowl element, via dragging the bowl element over a surface of snow. In a preferred embodiment, the snowman making apparatus comprises three bowl elements of differing sizes, for making a snowman comprising a base segment; a mid-section segment; and a head segment, of different sizes.
US11130067B2 Swing ride attraction with control means for controlling the swing
The invention relates to an attraction (1) for amusement rides, such as a fairground attraction or an amusement park attraction, comprising a mast (10), a base frame (13), which is rotatably attached to the mast and which extends radially from the mast, means for rotating the base frame, a plurality of subframes (20), each comprising a stiff connecting arm to which a gondola with one or more passenger seats is attached. The subframes (20) are circumferentially distributed, each pivotably suspended by means of the connecting arm on the base frame (13), such that the subframes with gondolas swing upon rotation of the base frame under the influence of the centrifugal force. The attraction is further provided with control means for controlling the swing of the subframes with gondolas relative to the base frame, which control means are arranged to move the center of gravity of the subframe (20) relative to the base frame (13).
US11130066B1 System and method for synchronization of messages and events with a variable rate timeline undergoing processing delay in environments with inconsistent framerates
System and method that handles the inconsistent processing of interactive media (e.g. digital games, music visualization software, video playback software, animation software, etc.) and the generally consistent timeline delay to enable synchronization of messages and events with the playback of potentially variable-rate timelines.
US11130064B2 Systems and methods for biofeedback gameplay
Techniques are disclosed for deploying game-based therapy correlated with, but independent from, an executing game program. In general, game content within a display can be improved with an overlay of visual therapeutic content such as a visual indicator of a current emotional or physiological state, along with visual features or effects that alter game difficulty. A variety of visual effects can usefully be integrated with third-party game content with requiring direct computation access to the executing game code. For example, effects such as dimming, fading, pixelating, or fogging can be rendered within active regions of a game window independently from, but correlated with the visual content of, the current game. This is suitable for delivering treatment for a range of cognitive and similar disorders and permits rendering of user-specific therapeutic content in combination with third-party games and gaming platforms.
US11130058B2 Game machine and storage medium
The present invention provides a game machine that is capable of utilizing movements of at least a part of the body of the player as play actions. A game machine provides a dance game that advises of a performance timing at which an action constituting a dance is to be executed, and, evaluates the actual performance timing of that. The game machine includes a camera which detects either a crouching action that causes the head of a player to move lower than a lower-limit position or a return movement that causes the head to move higher than an upper-limit position. The game machine advises of a timing at which such crouching action or the like is to be executed so that the crouching action or the like function as the actions of the dance, and, when such crouching action or the like is detected, evaluates the actual timing of that.
US11130055B2 System and method for granting remote access to a video game executed on a video game console or network client
Systems for granting remote access to, and methods of playing, a video game executing on a video game console coupled to a computer network or video games executing on hosting clients of a computer network. One embodiment of the system includes: (1) a stream distributor configured to receive a video stream conveying a view of a gamespace of the video game from the video game console via the computer network and transmit the video stream toward a remote client via the computer network and (2) a response receiver associated with the stream distributor and configured to receive a response stream from the remote client via the computer network and transmit the response stream toward the video game console.
US11130053B2 Game contacting smart objects
An interactive game can include a first target object comprising a first body, a first controller, and a first sensor coupled to the first controller, where the first sensor measures a parameter that indicates when the first body is contacted. The interactive game can also include an initiating object, and a first player positioned a distance from the first target object, where the first player propels the initiating object toward the first target object. The first controller, based on the first parameter measured by the first sensor, can determine when the initiating object contacts the first target object and awards a point to the first player for contacting the first target object. The first controller can communicate a score of the first player to the first player.
US11130051B2 Server device, and storage medium used in same
Provided is a server device that is capable of reflecting a game activity track record in evaluation results of a game video. A center server is connected via a network to a user terminal that displays videos and manages evaluation results of each user when the videos are evaluated by the users. In addition, if a game video related to a game provided by the user terminal is displayed on the user terminal, the center server stores play data described so as to associate a user ID with information on the presence or absence of each user's play track record of the game. The center server classifies the evaluation results, on the basis of the information on the presence or absence of a play track record, into mutually separate special evaluation results and general evaluation results, and provides the evaluation results so as to include the special evaluation results.
US11130048B2 Three-dimensional puzzle containing moveable elements
Systems, devices, and methods including one or more code rings, each code ring comprising one or more sides on an outer surface and one or more code ring alignment indentations on an inner surface; and one or more inner combination rings, each inner combination ring comprising one or more inner combination ring alignment protrusions on an outer surface and a combination indentation on an inner surface; where each of the one or more code ring alignment indentations receive each of the one or more inner combination ring alignment protrusions, where each inner combination ring may be removable and rotatable relative to each code ring of the one or more code rings, and where the combination indentation may be proximate an unlocked side of each of the one or more code rings.
US11130046B2 Dual axle skateboard and truck with outboard secondary wheels and method
Improved skateboards and methods of obtaining or providing skateboards with improved trucks. Trucks have two axles or axes, two primary wheels, and two secondary wheels, and skateboards have eight wheels, four in front and four at the rear portion of the skateboard. The four primary wheels support most or all of the weight of the skateboard when the skateboard is on a flat surface, and the two secondary wheels support the weight of one portion of the skateboard (e.g., front or rear) when the primary wheels cross a crack (e.g., a sidewalk contraction joint). In various embodiments, the secondary wheels are located outboard of the primary wheels. Further, in a number of embodiments, the axis of rotation or axle of the primary wheels remains parallel to that of the secondary wheels, whether the skateboard is going straight or turning.
US11130042B2 Smart device
An Internet of Thing (IoT) device includes a sensor coupled to a processor; and a transceiver coupled to the processor. Blockchain smart contracts can be used with the device to facilitate secure operation.
US11130040B2 System and method for evaluating team game activities
A system and method are provided for creating and evaluating computational models for games (e.g., individual or team sports games, etc.), team performance, and individual player performance evaluation. The method comprises obtaining data associated with the team game, the information comprising at least one individual player activity, at least one team activity, at least one game event, and a location in space and time for each of the events and activities; generating quantitative values for the data associated with the team game; and evaluating either or both an individual player and a team using the quantitative values.
US11130039B1 Wheelchair accessible fitness equipment
Fitness equipment is installed in or on a ground surface for enabling an exercise by a user in a wheelchair. The fitness equipment includes a base operably installed adjacent a wheelchair space. The equipment includes an upwardly extending post the base to an upper end, and includes a front facing surface which faces the wheelchair space, and an opposed rear facing surface. A pneumatic cylinder has a first pivot connected to the rear facing surface, and a second pivot attached to a cam, the cam being pivotally attached to a pivot mount of the upwardly extending post. A U-shaped arm assembly that extends from the cam, around the upwardly extending post, to a pair of laterally spaced ends positioned on either side of the wheelchair space without extending into the wheelchair space.
US11130037B2 Boxing fitness device and detection method thereof
The present invention relates to a boxing fitness device and a detection method thereof, the boxing fitness device of the present invention includes a frame, punching zones, prompting devices, sensing devices, a first wearable device, a second wearable device and a computation unit. The punching zones are disposed in the frame and the prompting devices are disposed on the punching zones, respectively. When a left hand or a right hand of a user touches one of the punching zones, the sensing devices can sense a first to-be-sensed part of a first wearable device or a second to-be-sensed part of a second wearable device worn on the hands of the user. As a result, the boxing fitness device and the detection method thereof of the present invention can sense the first to-be-sensed part and the second to-be-sensed part to detect the user's correct punching action.
US11130034B2 Sports game with slot clip system
A roundnet game and components are provided. The roundnet includes a plurality of legs. Each of the plurality of legs contains a first leg socket and a second leg socket. The roundnet further includes a plurality of slotted tubing attached to the plurality of legs forming a perimeter of the roundnet. The roundnet further includes each of the slotted tubing with at least one slot. The roundnet further includes a plurality of track of clips. The roundnet further includes at least one track of clips attached to the at least one slot in each of the plurality of slotted tubing. The roundnet further includes a net forming a playing surface about the perimeter of the roundnet.
US11130029B2 Support structures for golf club head
A golf club head, preferably a putter head, comprising at least one structural support member is disclosed herein. The structural support member has a smooth, organic-looking aesthetic, with a continuously changing curvature along its spline and at least one surface, and preferably connects one portion of the golf club head to another portion. Where the support member connects to other portions of the golf club head, the surfaces of the member have a curvature that changes smoothly and continuously, lacking any sharp corners.
US11130027B2 Golf club head
A golf club head includes a head body having a crown, sole and skirt therebetween, the head body defining an opening in a front portion and having a frame support around the periphery of the opening. A face plate is mounted within the opening and has a transition radius along one or more edges to at least partially wrap around one or more of the crown, sole and skirt. The head includes thin wall zones in the crown and skirt, a hosel flush with the crown and a weight mounted in the sole proximate to the face plate, such that the golf club head has a center of gravity located relatively low and forward in proximity to the face plate.
US11130025B2 Golf club heads with energy storage features
Embodiments of a golf club head with a plurality of energy storage features are presented herein. In some embodiments, a golf club head comprises a body comprising a strike face, a heel region, a toe region opposite the heel region, a sole, a crown, a channel, a chamfer spanning between a strike face and the crown, and an internal radius transition feature from the strike face to at least one of the sole or the crown.
US11130022B1 Randomized exercise system
According to one example, an exercise system includes a base, a vertical housing extending vertically outward from the base, a first weighted touchpoint moveably coupled to the vertical housing, a second weighted touchpoint moveably coupled to the vertical housing, and one or more weight systems configured to provide weight to the weighted touchpoints. The exercise system further includes a control system that determines randomized workouts that include a random selection of a muscle group, a weight amount, a weight differential, a number of sets of an exercise, and/or a number of repetitions in the set. The control system may also cause the weight system to adjust the weight of the weighted touchpoints based on the randomized workout.
US11130021B2 Trampoline for use as an input device for an electronic game
A trampoline as a controller or an input device for playing games, including a frame having a flexible mat divided into input zones and one or more neutral zones, a sensor arrangement to detect activity on the flexible mat, a controller configured to determine the bounce location and bounce zone of the activity and provide this information to a feedback generator for playing games on the trampoline, such that a user uses the trampoline to play games by jumping on the input and neutral zones.
US11130019B2 Sports events broadcasting systems and methods
A system and method for recording and broadcasting motion of a sports ball and individual players includes a sports ball with cameras embedded within for recording trajectory and locomotion, a sensor module for storing video footage and telemetry metadata, and cameras mounted on the sports equipment of individual players. The sensor module includes an Inertia Measuring Unit, a transceiver, a memory, a power source, and a processor, all operatively connected to one another. The sports ball sends data to a wireless data transmission grid mounted under a sports pitch and/or to antennas for transfer to a data processing server which determines a real ball direction thereafter sent to a stadium camera system that generates further 360 degree action-focused broadcasting data. The data is sent to the processing server which processes the raw footage received from the sports ball and individual players to produce clean footage for various applications.
US11130011B2 Closed trampoline frame and trampoline with the closed trampoline frame
A closed trampoline frame includes multiple frame pipes which are connecting in turns, the adjacent frame pipes are connected by a frame connector. The frame connector is a T-pipe composed of a horizontal pipe and a vertical pipe. Its outer diameter of the horizontal pipe is smaller than that of the frame pipe; its two ends of the horizontal pipe are inserted into the adjacent frame pipes. The top and the bottom of the frame pipe are provided with upper frame holes and lower frame holes. The top and the bottom of the horizontal pipe are provided with upper holes and lower holes. When its two ends of the horizontal pipe are inserted into the adjacent frame tubes, each of the upper holes coincides with one of the upper frame hole, and each of the lower holes coincides with one of the lower frame hole.
US11130009B2 Rotorcraft fall restraint protection attach points and mechanism systems
The present invention includes a safety apparatus and method for protecting users during maintenance operations for a rotorcraft comprising: at least one permanent, semi-permanent, or detachable safety bar, strap, fastener, hook, or loop that is attached or attachable to a rotorcraft, wherein the safety bar, strap, fastener, hook, or loop is positioned in an area or surface between a windshield of the rotorcraft and a tail boom of the rotorcraft and is connectable to a user safety device to provide fall protection from the area or surface.
US11130007B2 Breathing tube retainer and method of using same
Various embodiments of a breathing tube retainer and a respirator that utilizes the breathing tube retainer are disclosed. In one or more embodiments, the breathing tube retainer can include a mask attachment portion configured to connect the retainer to a face mask of a respirator, and a tube attachment portion including an arm that connects the tube attachment portion to the mask attachment portion. The tube attachment portion can further include a tube receiver configured to receive a breathing tube of the respirator.
US11130004B2 Brachytherapy apparatus and methods for using them
Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
US11130001B2 Display apparatus including a lens
A display apparatus providing light therapy includes a display panel configured to display an image to a display region based on input image data, and a lens part disposed on the display panel, the lens part configured to focus the image displayed by the display panel toward a first region in a therapy mode, in which the first region is smaller than the display region, and the first region may correspond to a position of a user's face.
US11129997B2 Adaptive self-testing and stress analysis of medical devices
An improved self-testing method is described which is incorporated into a defibrillator. The method performs a self-testing protocol which operates on a first frequency until a threshold condition is reached. When the threshold condition is reached, the self-testing protocol switches to a second frequency. Such a method enables quicker identification of a failure mode in a population of defibrillators, while maintaining acceptable battery life in the device.
US11129994B2 Sensor-based phrenic nerve stimulation detection
A method and device for detecting phrenic nerve stimulation (PNS) in, or using, a cardiac medical device. A test signal sensitive to contraction of a diaphragm of a patient may be sensed and signal artifacts of the test signal within each of a first window of the test signal prior to a predetermined cardiac signal and a second window of the test signal subsequent to the predetermined cardiac signal may be determined. The PNS beat criteria may be evaluated, for example, using the test signal, which may be a heart sounds signal.
US11129985B2 Devices, systems, and methods for stimulation therapy
Generally discussed herein are systems, devices, and methods for providing a therapy (e.g., stimulation) and/or data signal using an implantable device. Systems, devices and methods for interacting with (e.g., communicating with, receiving power from) an external device are also provided.
US11129984B2 Method and apparatus to provide safety checks for neural stimulation
In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.
US11129981B2 Disc therapy
Apparatus is provided that includes one or more intra-pulposus exposed electrode surfaces, and a support structure along which the one or more intra-pulposus exposed electrode surfaces are disposed. The support structure is configured to be implanted within a nucleus pulposus of an intervertebral disc of a subject, and to be shaped as a partial ring or a complete ring after implantation. The apparatus further includes one or more extra-pulposus exposed electrode surfaces, which are configured to be implanted outside the nucleus pulposus, in electrical communication with the disc. Control circuitry is provided, which is configured to: configure the intra-pulposus exposed electrode surfaces to be cathodes, and the one or more extra-pulposus exposed electrode surfaces to be one or more anodes, and drive the intra-pulposus exposed electrode surfaces and the one or more extra-pulposus exposed electrode surfaces to electroosmotically drive fluid into the nucleus pulposus. Other embodiments are also described.
US11129977B2 Systems and methods for therapeutic agent delivery
According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject.
US11129964B2 Trapping sheaths and guide catheters
Introducer sheaths and (e.g., guide) catheters with inflatable trapping elements for trapping and/or stabilizing devices (e.g., guidewires, catheters, and/or the like) in a primary lumen of the sheath or catheter. Such sheaths and catheters may be configured for endovascular, endoscopic, laparoscopic, and/or urological procedures.
US11129958B2 Sleep-inducing device
A sleep-inducing device, including: 1) a probe including a heart rate sensor detecting a heart rate of an infant's mother; 2) a sampling module collecting data with regard to the heart rate detected by the probe; 3) a first microcontroller unit (MCU) calculating the data transmitted from the sampling module and outputting a heart rate signal; 4) a second microcontroller unit (MCU) receiving and processing the heart rate signal transmitted from the first MCU; 5) a keyboard inputting, controlling and adjusting parameters of the second MCU; 6) a display displaying an operation/control state of the device; 7) a loudspeaker playing audio data of the heart rate signal processed by and transmitted from the second MCU; 8) a first memory storing the audio data of the heart rate signal; 9) a low dropout regulator (LDO) providing a constant voltage to the second MCU; and 10) a power supply.
US11129953B2 Foam respiratory mask
A patient interface for delivering breathable gas to a patient includes a foam interfacing portion adapted to provide a nasal interface to contact under and around the patient's nose in use and including an orifice adapted to surround both the patient's nares in use, and a positioning and stabilizing structure to support the foam interfacing portion in an operative position on the patient's face. The positioning and stabilizing structure is structured to provide a range of rotational, axial, and/or lateral movement to the foam interfacing portion while maintaining a sufficient interface and resisting the application of tube drag and/or headgear tension to the foam interfacing portion.
US11129951B2 Medical vaporizer
A medical vaporizer includes a liquid drug reservoir configured to receive and hold a liquid drug. A low power graphical display is configured to intermittently receive power. The low power graphical display is operable to visually present information and maintain the visual presentation of information in the absence of power. A controller is configured to intermittently receive power and upon receiving power the controller operates to determine a status of a medical vaporizer. The controller operates the low power graphical display to present the status of the medical vaporizer as visually presented information.
US11129947B2 Mask for administration of inhaled medication
A breathing mask for use in administering inhalable medications to a patient in need of an inhaled drug is provided. The mask disclosed herein is particularly useful for use with very young children. The mask is made from a flexible molded plastic silicone or elastomeric material, and has an anthropometrically/anatomically/ergonomically contoured shape to provide a good seal, a comfortable fit, and minimal dead space within the mask. The airway is aligned with nose. There may be an orifice for use with a soother device to calm a child using the mask. Also provided is a visual flow indicator to provide an indication of the quality of the seal of the mask on the face.
US11129946B2 Guiding device for dental anesthesia
The invention provides a device for the practice of oral medicine, including dentistry. Specifically, the invention relates to a guiding device that helps to prevent injecting beyond the pterygomandibular space during inferior alveolar nerve block for which purpose the injection is administered in the vicinity of the inferior alveolar nerve. The device has a retro-mandibular tip (12) operably linked to a guide tube (14) by a connecting unit (20, 22, 24), the guide tube (14) is adapted to receive a syringe and has a stopper mechanism (19) to stop the advancement of the syringe such that its needle is located at a predetermined distance from the posterior edge of the mandibular ramus.
US11129945B2 Auto-injector device
An auto-injector device comprising an injector body having a proximal end and a distal end; a syringe received in the injector body; a needle disposed in a first end of the syringe to extend toward an opening in the distal end of the injector body; and a sealing element disposed at the distal end of the injector body for making a seal against a patient's skin. The auto-injector is configured to generate a reduced pressure to draw the auto-injector device against the patient's skin. The auto-injector device comprises a pressure-reducing mechanism configured to generate the reduced pressure within the injector body during an injection process. The pressure reducing mechanism comprises a moveable member configured such that movement of the moveable member from a first position to a second position enlarges a closed volume within the injector body to generate the reduced pressure within the closed volume.
US11129944B2 Method for producing needle-equipped outer tube and needle-equipped outer tube
A method of manufacturing a needle-equipped outer tube includes a preheating step comprising heating a distal end connecting section to a temperature at or below a softening point of a material forming an outer tube member with a joint member inserted in a distal end connecting section of the outer tube member, and with a needle being inserted or inserted and fixed in the needle insertion hole; and a joint member welding step, performed after the preheating step, comprising thermally welding the joint member to the distal end connecting section of the outer tube member with a distal end portion of the joint member pressed toward the proximal end of the joint member by a pushing member with a pressing force in a range of 4 N to 30 N.
US11129938B2 Ambulatory medical device update without interruption of therapy delivery
Systems and methods are disclosed herein for updating an application controlling an ambulatory medical device such that application updates can be identified, downloaded and installed without interrupting therapy provided by the ambulatory medical device to a subject. The ambulatory medical device may receive an indication that an update to an application executing on the ambulatory insulin pump is available, establish a communication connection to a host computing system configured to host the application update, and download the application update. The disclosed systems and methods can determine an execution time of an installation and install the downloaded application update without interrupting therapy provided by the ambulatory medical device to the subject.
US11129933B2 Syringe pump, and related method and system
A method for discharging fluid from a syringe and for mitigating occlusion conditions includes actuating the plunger of a syringe into a barrel. The method monitors fluid pressure within the barrel of the syringe and determines that an occlusion exists when the fluid pressure exceeds a predetermined threshold. The method actuates the plunger out of the barrel by a predetermined amount in response to the detected occlusion and actuates the plunger of the syringe into the barrel until a measured fluid pressure within the barrel of the syringe exceeds another predetermined threshold.
US11129932B2 Fluid drug cartridge type identification
This disclosure provides a method of determining a cartridge type of a cartridge used with a fluid drug injection system having a pump that receives a fluid drug cartridge. The fluid drug cartridge has a barrel filled with a fluid drug solution and a plunger within the barrel that forces the fluid drug solution through an outlet. An actuator of the pump is moved to contact or to move the plunger and a force sensor is used to measure force data during the movement. The force data is descriptive of the force applied to the plunger. A feature signal is determined from the force data. The feature signal can be a force modulation amplitude, a force modulation duration or a force modulation number. The cartridge type is assigned using the feature signal. Also disclosed is a fluid drug injection system and a cartridge for use therewith.
US11129930B2 System and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma (PRP)
A system for obtaining plasma enriched in platelets is disclosed which is closed to the atmosphere. The system includes: a collection tube containing an anticoagulant portion and a separation gel; a first collection syringe adapted to collect a portion of fluid relatively depleted in platelets from said collection tube after centrifugation; and a second collection syringe adapted to collect plasma enriched in platelets from said collection tube after centrifugation, said second collection syringe further comprising a filter unit adapted to filter cells included in said plasma enriched in platelets.
US11129927B2 Method for forming hydrogels and materials therefor
The present invention provides a dry powder that is suitable for use in forming a hydrogel and characterized by a stable composition at ambient conditions. The dry powder includes a prepolymer including a straight chain polyethylene glycol, and a thermally activated free radical initiator selected from the group consisting of sodium persulfate, potassium persulfate, and ammonium persulfate. The present invention also provides a method of forming the dry powder, and a method of preparing a hydrogel where a reaction mixture is formed including the dry powder and a buffered aqueous solution.
US11129922B2 Xenotransplantation products and methods
A biological product for clinical xenotransplantation into a human and a method of preparing biological product for clinical xenotransplantation into a human involving producing a non-wild type, biologically engineered swine having a biologically engineered genome such that the swine does not express one or more extracellular surface glycan epitopes, is free of certain pathogens, is reared according to a bioburden-reducing procedure in a closed designated pathogen free herd, wherein the biological product is harvested following the swine being euthanized and the product is aseptically removed from the swine, the biological product is processed involving sterilization and storing the product in a sterile container, and the product does not contain one or more extracellular surface glycans, is free of certain designated pathogens, is biologically active and comprises live cells and tissues capable of vascularizing after xenotransplantation.
US11129921B2 Concentrated aqueous silk fibroin solution and use thereof
The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
US11129920B2 Tissue-adhesive biomedical materials
The invention is directed to a biodegradable tissue-adhesive polyurethane polymer comprising at least one amorphous segment and at least one polyurethane segment, wherein at least one of said polyurethane segment comprises a tissue-reactive functional group. A further aspect of the invention is directed to biodegradable tissue-adhesive medical devices, based on the polyurethane polymer, having the structure of a sheet, foam, stent, tube or gel. The polyurethane polymer and the device can be used in medical application.
US11129919B2 Absorbent article with activatable material
Material webs suitable for use in conjunction with disposable absorbent articles are disclosed herein. The material webs comprise a melt additive that when subjected to thermal energy may be encouraged to bloom across the entirety of the web or in localized areas of the web where localized thermal energy is applied.
US11129911B2 Assessment of coronary heart disease with carbon dioxide
There are provided methods for diagnosing coronary heart disease in a subject in need thereof comprising administering an admixture comprising CO2 to a subject to reach a predetermined PaCO2 in the subject to induce hyperemia, monitoring vascular reactivity in the subject and diagnosing the presence or absence of coronary heart disease in the subject, wherein decreased vascular reactivity in the subject compared to a control subject is indicative of coronary heart disease. There are also provided methods for increasing sensitivity and specificity of BOLD MRI.
US11129908B2 Gene therapy vectors for treating heart disease
The present disclosure provides methods and compositions useful for the treatment or prevention of heart disease. In particular, the present disclosure provides a vector comprising a modified troponin T promoter operatively linked to a therapeutic gene product for the treatment or prevention of heart disease, e.g., cardiomyopathy. The gene product may be MYBPC3. The disclosure also provides recombinant adeno-associated virus (rAAV) virions, rAAV viral genomes, and expression cassettes and pharmaceutical compositions thereof. The disclosure further provides methods for treating a disease or disorder, such as heart disease.
US11129907B2 Self-assembled ribonucleoprotein nanoparticles
Provided are a self-assembled polyribonucleotide-protein complex including a polyribonucleotide including a plurality of first repeating units having a single guide RNA (sgRNA) region and a small interfering RNA (siRNA) region; and one or more nuclease proteins binding to the sgRNA region, and use thereof.
US11129905B2 Bivalent, bispecific binding proteins for prevention or treatment of HIV infection
Provided herein are bivalent, bispecific binding proteins that specifically bind to two different HIV-1 Env protein epitopes.
US11129897B2 Fast-acting plant-based medicinal compounds and nutritional supplements
Plant-based medicinal compounds or nutritional supplements in various carrier combinations are described. The carriers can include N-acylated fatty amino acids, penetration enhancers, and/or various other beneficial carriers. The plant-based composition/carrier combinations can create administration benefits.
US11129896B2 Topical formulations and treatments
Provided is a pharmaceutical formulation and a method associated therewith for treating bacterial vaginosis. The pharmaceutical formulation includes from 10 to 25 weight parts of poloxamer F127, from 0.5 to 3.0 weight parts of xanthan gum, from 70 to 90 weight parts of water, and a therapeutically effective amount of a pharmaceutical active ingredient. The pharmaceutical formulation may also include from 0.5 to 1.5 weight parts of benzyl alcohol.
US11129894B2 Sensitizing cells to proton radiation
Materials and methods for enhancing the effectiveness of proton radiation therapy (e.g., high linear energy transfer (LET) proton radiation therapy) against tumor cells are provided herein.
US11129893B2 Pharmaceutical composition for treating and/or preventing cancer
An object of the present invention is to identify a cancer antigen protein specifically expressed on the surface of cancer cells and provide use of an antibody targeting the cancer antigen protein as a therapeutic and/or prophylactic agent for cancer. A pharmaceutical composition for treating and/or preventing cancer comprising an antibody or a fragment thereof having immunological reactivity with CSPG5 protein consisting of any one of amino acid sequences represented by SEQ ID NOs: 8, 4, 6, 10, and 12 and an amino acid sequence having an amino acid identity of 80% or more to the amino acid sequence, or a fragment thereof consisting of 7 or more consecutive amino acids, as an active ingredient.
US11129891B2 Cytomegalovirus surface protein complex for use in vaccines and as a drug target
Immunogenic compositions and prophylactic or therapeutic vaccines for use in protecting and treating against human cytomegalovirus (CMV) are disclosed. Subunit vaccines comprising a human CMV protein complex comprising pUL128 or pUL130, and nucleic acid vaccines comprising at least one nucleic acid encoding a CMV protein complex comprising pUL128 or pUL130 are described. Also disclosed are therapeutic antibodies reactive against a CMV protein complex comprising pUL128 or pUL130, as well as methods for screening compounds that inhibit CMV infection of epithelial and endothelial cells, methods for immunizing a subject against CMV infection, methods for determining the capability of neutralizing antibodies to inhibit CMV infection of cell types other than fibroblasts, and methods of diminishing an CMV infection.
US11129890B1 Non-integrating HIV-1 comprising mutant RT/IN proteins and the SARS-CoV-2 spike protein
The present invention is directed to recombinant lentiviral particles that array the SARS-CoV-2 spike (S) protein on their surface (“SARS-CoV-2 S Protein Lentiviral Particles”), and that optionally comprise an additional copy of a polynucleotide encoding the SARS-CoV-2 spike (S) protein in their viral genome, and to methods for the production of such lentiviral particles. The invention particularly pertains to such SARS-CoV-2 S Protein Lentiviral Particles that have been engineered to be incapable of mediating the integration of their lentiviral genome into the chromosomes of infected cells and/or to be incapable of mediating the reverse transcription of their lentiviral genome. The present invention is also directed to “SARS-CoV-2 S Protein Lentiviral Vaccine” pharmaceutical compositions that comprise such SARS-CoV-2 S Protein Lentiviral Particles. The present invention is additionally directed to the use of such SARS-CoV-2 S Protein Lentiviral Vaccine pharmaceutical compositions for providing immunity to COVID-19 infection to humans and other mammals, either directly or as an inactivated form.
US11129887B2 Influenza hemagglutinin proteins and methods of use thereof
In some embodiments the present invention provides influenza hemagglutinin (“HA”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
US11129885B2 Virus like particle of hepatitis B virus pre-S protein
As disclosed herein, the preS antigen on infectious hepatitis B virus (HBV) particles can provide B and T ceil epitopes that promote the humoral and cellular responses and enhance the seroprotection rate by overcoming non-responsiveness to the S antigen-only vaccines. Therefore, compositions and methods are disclosed using the preS antigen to develop vaccines and immune therapies for treating or preventing hepatitis B infection, in particular, virus-like particles (VLPs) are disclosed that contain the preS antigen on its surface. These VLPs can be used alone or in combination with vaccines containing the hepatitis B surface antigen (HBsAg) to vaccinate subjects against HBV as well as to activate T ceils for adoptive T cell therapy to eradicate HBV infected hapatocytes.
US11129884B2 Bacterial vaccine components and uses thereof
Agents, compositions, methods and kits useful for the treatment and diagnosis of Staphylococcal intramammary infection are disclosed. The agents, compositions, methods and kits are derived from genes expressed during Staphylococcal intramammary infection, and more particularly genes SACOL0029, based on the gene nomenclature from the Staphylococcus aureus COL (SACOL) genome.
US11129880B2 Method for promoting insulin secretion
The present invention relates to a method for promoting insulin secretion comprising administering an effective amount of plasminogen to a subject; furthermore, the present invention relates to a medicament for promoting insulin secretion.
US11129875B2 Osteoarthritis treatment with chemokine-loaded alginate microparticles
The present invention provides microparticles that induce the migration of multipotent stem cells to the anatomical site of the microparticles. Various release profiles are demonstrated that depend upon the relative concentration of alginate in the chemokine-loaded microparticle. Local administration and/or intraarticular injection of the microparticles are useful in conditions such as osteoarthritis. Targeted systemic delivery of the alginate chemokine microparticles to distant anatomical sites subjected to autoimmune disease symptomology can be performed by encapsulation within liposomes having targeting ligands. Consequently, upon the creation of the appropriate chemokine gradient, multipotent stem cells will migrate to the distant anatomical site where the liposomes are attached.
US11129874B2 Nucleic acids encoding FGF21-Fc fusion proteins
The invention relates to nucleic acids encoding fusion proteins comprising polypeptide and protein variants of fibroblast growth factor 21 (FGF21) with improved pharmaceutical properties. Also disclosed are vectors and host cells comprising the same and methods of producing the fusion proteins.
US11129872B2 Methods of making and using soluble MHC molecules
Provided herein are methods of making a detectably-labeled, soluble MHC molecule that can be used in a novel Kon-rate assay and an improved TCR ligand koff-rate assay.
US11129871B1 Compositions and methods for treating and preventing endoplasmic reticulum (ER) stress-mediated kidney diseases
Among the various aspects of the present disclosure is the provision of methods and compositions to treat or prevent an endoplasmic reticulum (ER) stress-mediated kidney disease in a subject, the method comprising administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of an ER calcium channel stabilizing agent or an ER stress modulating agent (e.g., mesencephalic astrocyte-derived neurotrophic factor (MANF), compound K201).
US11129869B2 Pharmaceutical compositions
The present invention relates to an ionic complex comprising a cationic polypeptide and an anionic excipient selected from: a PEG-carboxylic acid; a fatty acid having 10 or more carbon atoms; an anionic phospholipid; and a combination thereof. The invention also relates to a pharmaceutical composition comprising the ionic complex of the invention and a pharmaceutically acceptable carrier. The cationic polypeptide of the ionic complex has pharmacological activity and the complex can provide a more desirable pharmacokinetic profile for the cationic polypeptide of the complex as compared to the cationic polypeptide alone following administration. As such, the invention also relates to the use of the ionic complex and pharmaceutical composition comprising same to treat a subject suffering from a disease or disorder that is responsive to the cationic polypeptide of the ionic complex.
US11129867B2 Method of treating cancer cells
The present invention discloses a method of treating cancer cells. The method comprises administrating a composition comprises a rhodamine or rhodamine derivative conjugated to a peptide comprises an amino acid sequence of SEQ ID NO: 1 to a subject in need, and activate the composition with light.
US11129865B2 NEUPANEX®: neuroprotective, neuroregenerational, and neurogenesis supporting supplement combination
The present invention provides a dietary supplement that contains necessary ingredients for neurological protection and neurogenesis in one formulation. This dietary supplement comprises combinations of vitamins and substances that are naturally endogenous to the brain, are known to decline with age, injury and disease and are essential for membrane structure, mitochondrial respiration and stem cell differentiation.
US11129864B2 Method for obtaining a plant extract and associated compositions
The invention relates to a tablet or capsule containing a plant extract, to assist in the treatment or prevention of disorders or diseases. The tablet or capsule includes bioconverted products provided by fermenting Withania Somnifera extract, Emblica officinalis extract, and Bacopa monnieri extract.
US11129861B2 Methods for treating inflammatory diseases
The present invention provides a composition containing, as active ingredients, Panax ginseng, Adenophora triphylla, Wolfiporia extensa, Rehmannia glutinosa, and Mel for an antitussive, expectorant, or anti-inflammatory action, and a composition for preventing, alleviating, or treating a respiratory disease. The present invention provides a compositions having excellent effects compared with an existing antitussive agent and expectorant agent. The compositions of the present invention are a naturally derived material and has little cytotoxicity, and thus is expected to be safely used as a medicine or food composition having antitussive, expectorant, and anti-inflammatory effects.
US11129853B2 Processes for making and using a mesenchymal stem cell derived secretome
The present application provides methods and processes for making and using a mesenchymal stem cell secretome, as well as methods for treating ocular conditions and/disorders with the mesenchymal stem cell secretome described herein.
US11129851B2 Stem cell therapy in endometrial pathologies
The invention generally relates to the ability of autologous CD133+ bone marrow stem cells (BMDSC) to induce endometrial regeneration and treat endometrial pathologies such as Asherman's syndrome and endometrial atrophy. Methods to induce endometrial regeneration are provided, which comprises administering an effective amount of autologous CD133+ bone marrow derived stem cells (BMDSC) into uterine arteries of a subject in need thereof to induce endometrial regeneration.
US11129846B2 Dosage form for treating severe asthma
Methods are provided for treating corticosteroid-resistant asthma in a patient, comprising decreasing Interferon Regulatory Factor 5 (IRF5) activity in the patient. Antisense or RNA interference reagents and methods can be used to decrease IRF5 activity in the patient.
US11129845B2 Compositions and methods for the delivery of nucleic acids
A compound comprising formula (I): wherein R1 is an akylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted akyl group, an akenyl group, an acyl group, an aromatic group, polymer, a targeting group, or a detectable moiety; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.
US11129842B2 Methods and compositions for treating diseases related to imbalance of essential fatty acids
This invention relates to compositions containing combinations of a balanced phosphatidylcholine composition and one or more cannabinoids, a natural or synthetic derivative thereof, or a salt thereof, and kits containing such combinations and methods of using such combinations to treat subjects suffering from an imbalance of fatty acids and related diseases or disorders. This invention also relates to the synergistic effect of such combination therapies in humans.
US11129840B2 Methods for identifying novel dosing regimens
Methods of treating a Gram negative bacterial infection comprising a co-administration regimen of an effective amount of fosfomycin together with at least one antimicrobial agent selected from the group consisting of piperacillin-tazobactam, ceftazidime and meropenem to an infected subject. A further method of treating a subject with a bacterial infection that includes infection with a “resistant” mutant subpopulation selected from the group consisting of Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Acinetobacter baumannii and E. coli, the method comprising (a) obtaining a sample from a subject suffering from a bacterial infection; (b) identifying the presence of the “resistant” mutant subpopulation in said sample; and (c) co-administering fosfomycin and at least one antimicrobial agent to the subject, wherein after the co-administration, the bacterial density is effectively reduced and the “resistant” mutant subpopulation is inhibited.
US11129839B2 Minocycline compounds for biodefense
Methods of treating or preventing a bacterial infection in a subject are disclosed herein, wherein the bacterial infection is caused by a bacterium which can be used as a biological weapon. Also disclosed is a pharmaceutical composition comprising the compound of the present invention for treating or preventing a bacterial infection in a subject, wherein the bacterial infection is caused by a bacterium which can be used as a biological weapon.
US11129838B2 Methods of inhibiting pathological angiogenesis
This invention is based on the discovery that many eye conditions associated with aging are mediated at least in part by cells bearing a senescent phenotype. Senescent cells accumulate with age, and express factors that contribute to the pathophysiology of age related conditions. The data show that in age-matched patients, the severity of age-related conditions correlates with the abundance of senescent cells, and that clearing senescent cells can help abrogate the condition. Small molecule drugs that remove senescent cells from affected tissue in the eye are provided that have special efficacy in treating ophthalmic conditions. They not only inhibit progression of the disease, they can also reverse some of the pathophysiology—such as neovascularization and vaso-obliteration—that lead to vision loss. These senolytic agents have an appropriate dose and specificity profile to be effective in the clinical management of previously intractable ophthalmic conditions.
US11129834B2 Combinations and methods comprising a capsid assembly inhibitor
The present disclosure is directed to capsid assembly inhibitor compositions and methods for use in the treatment of hepatitis B virus infection.
US11129833B2 Methotrexate formulation
A liquid pharmaceutical composition comprises methotrexate free acid and a buffer, wherein the pH of the composition is in the range of 6.5 to 8.2. Processes for preparation of the liquid pharmaceutical composition are also described. The liquid pharmaceutical composition is useful in therapy.
US11129832B2 Biheteroaryl compounds and uses thereof
The present invention provides for compounds of Formula I-I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases). R1, R2, R3, X1, X2, A and Cy variable in Formula I-I all have the meaning as defined herein.
US11129831B2 Identification of agents displaying functional activation of dopamine D2 and D4 receptors
A method of treating psychosis, and the underlying antipsychotic formulation. The method includes administering a therapeutically effective amount of synthetic agents that selectively recruit β-arrestin to D2 receptors and have little-to-no binding to culprit receptors associated with weight gain and Type II diabetes. The synthetic agents can include SYA16263 and SYA16264, and/or derivatives or analogs thereof. The 1-(pyridin-2-yl)piperazine moiety was found to play a significant role in recruiting β-arrestin to D2 receptors. In other embodiments, the current invention relates to synthetic agents that are selective of D4 receptors for treatment of psychosis and erectile dysfunction. The synthetic agents can include SYA27287 and/or derivatives or analogs thereof. In all embodiments, extrapyramidal side effects are eliminated or minimized.
US11129828B2 Pyridazinone compounds and their use as DAAO inhibitors
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
US11129825B2 Polysubunit opioid prodrugs resistant to overdose and abuse
The invention provides compositions and methods for the treatment or prevention of pain. The invention provides constructs whereby hydrolysis of the construct by a specified gastrointestinal enzyme directly, or indirectly, releases an opioid when taken orally as prescribed. The gastrointestinal enzyme mediated release of opioid from constructs of the invention is designed to be attenuated in vivo via a saturation or inhibition mechanism when overdoses are ingested. The invention further provides constructs that are highly resistant to oral overdose, chemical tampering, and abuse via non-oral routes of administration.
US11129824B2 Small molecules for inhibiting chemokine activity and/or cancer cells growth
Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or inhibiting a kinase and/or in treating a disease or disorder associated with an activity of a kinase, such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B D, E, G and R1-R5 are as defined in the specification.
US11129822B2 Treating of side-effects resulting from chemodenervation
The present disclosure relates generally to methods of restoring neuromuscular transmission by locally administering an effective dose of a composition comprising an anticholinesterase to a non-responsive muscle. The disclosure also relates to methods of reversing a neurotoxin-induced muscle paralysis or muscle weakness, the method comprising locally administering a composition comprising an anticholinesterase to the patient.
US11129817B2 Solid dispersion forms of rifaximin
Provided herein are solid dispersions comprising rifaximin and pharmaceutical compositions and uses thereof.
US11129807B2 Methods of treating schizophrenia
Provided herein are methods for determining if a compound has potential efficacy for the treatment for a specific symptom domain of schizophrenia, such as for example, the treatment of a negative symptom of schizophrenia. In addition, provided herein are methods of determining the prominent symptom domain of a subject suffering from schizophrenia. Further, provided herein are various methods for the treatment of the negative symptoms, cognitive dysfunction symptoms, or both, associated with schizophrenia comprising administering to a subject a therapeutically or prophylactically effective amount of various compounds.
US11129803B2 Methods and compositions to inhibit tolerance to opioids
The present invention provides a method of inhibiting tolerance to an opioid by a human subject in need thereof. The method comprises administering an effective amount of a pharmaceutical composition to the subject during opioid therapy. The pharmaceutical composition comprises a) a non-steroidal anti-inflammatory drug (NSAID); and b) a co-agent selected from the group consisting of: fexofenadine, ketotifen, desloratadine, cetirizine, salts thereof and combinations thereof.
US11129802B2 Compositions and methods for delivering cannabidiol and ketone bodies
Disclosed herein are “ketonnabidiol” or “ketannabidiol” compositions including a combination of: (1) cannabidiol (CBD) and/or cannabidiolic acid (CBDA); (2) a ketone body component such as beta-hydroxybutyrate (BHB) and/or acetoacetate; and (3) a dietetically or pharmaceutically acceptable carrier. Also disclosed herein are methods of using such ketonnabidiol compositions for producing desired physiological effects, such as fat loss, in a mammal. The ketonnabidiol compositions beneficially enhance fat loss through ketosis while also reducing the duration and/or severity of unpleasant “keto flu” symptoms typically associated with ketosis.
US11129798B2 Fibrous dosage form
At present, the most prevalent pharmaceutical dosage forms, the oral immediate-release tablets and capsules, are granular solids. The problem of such solids is that their microstructure and properties are not predictable from physical models. As a consequence, product development and manufacture are resource-intensive and time-consuming, and quality control is statistical by testing instead of by design. Furthermore, the range of the drug release rate, and the variety of active ingredients that can be processed to a functional product, are limited in such dosage forms. Presented herein, accordingly, is a fibrous dosage form suitable for immediate-release applications prepared by a predictable liquid-based process. The fibrous dosage form includes a drug-containing solid comprising a three dimensional structural network of one or more drug-containing fibers.
US11129793B2 Retentive devices and systems for in-situ release of pharmaceutical active agents
Gastric retentive devices and systems including a gastric retentive element including at least one expandable compartment and a dosage form element including at least one active agent are provided. The devices and systems, as well as kits thereof are used in a method for in-situ release and delivery of the at least one active agent.
US11129789B2 Stabilized cosmetic compositions
A cosmetic composition includes a non-acid-resistant-grade ultramarine dye, a stabilizing agent, at least one additive, and water. The ultramarine dye may be present at a concentration of about 0.1% to about 0.4%, by weight, of the cosmetic composition and may include a trisulfur radical anion. The stabilizing agent may include baicalin and may be at a concentration of about 0.2% or less, by weight, of the cosmetic composition. The cosmetic composition may have a pH in the range of 6.5 to 8.0. A method of stabilizing a cosmetic composition includes forming a cosmetic composition including a non-acid-resistant-grade ultramarine dye, a stabilizing agent, at least one additive, and water. The method also includes adjusting a pH of the cosmetic composition to a predetermined value. The stabilizing agent inhibits degradation of the ultramarine dye, thereby stabilizing the cosmetic composition and inhibiting generation of an odor caused by degradation of the ultramarine dye.
US11129788B1 Sprayable film forming compositions for improving the performance of topical preparations
A spray-on film forming composition is designed to work with another topical preparation, such as a conventional cosmetic foundation or skincare product. The film forming composition is in direct contact with the cosmetic or skincare product. The spray-on film forming composition may be applied underneath a topical preparation (as a primer), on top of a topical preparation (as a mask), or both, depending on the benefit conferred. The spray-on film forming compositions of the invention are able to improve wearability and removability, increase shine, and deliver active ingredients. They are very clear, flexible and comfortable.
US11129786B2 Sulfate-free personal care compositions and methods for using such compositions
The present invention relates to sulfate-free aqueous personal care composition comprising a surfactant system comprising at least one methyl oleoyl taurate, one isethionate and one alkoxylated sulfosuccinate, and from about 0.2 pbw to about 15 pbw of a conditioning agent. It is also directed toward the use of such a composition for washing keratin substrates, in particular the hair or the scalp.
US11129783B2 Stable compact shampoo products with low viscosity and viscosity reducing agent
The invention relates stable compact low viscosity hair care compositions comprising: from about 20 weight % to about 45 weight % total surfactant; from about 2 weight % to about 25 weight % branched anionic surfactant with a tail having an alkyl chain with 12 to 18 carbon atoms; from about 5% weight % to about 30 weight % linear anionic surfactant with a tail having an alkyl chain with 12 to 18 carbon atom; from about 0.1 weight % to about 8 weight % of a viscosity reducing agent; from about 40 weight % to about 80 weight % of water; wherein the concentrated shampoo has Ratio of Linear anionic surfactant to Branched anionic surfactant of about 0.3 to about 5, wherein the concentrated shampoo has a viscosity of less than 3000 cP at 26.5° C.
US11129779B2 Thickening system in a percarbonate-containing blonding agent
The present disclosure relates to blonding agents which serve as a lightening agent for keratinic fibers, in particular human hair. Furthermore, the present disclosure relates to a cosmetic product comprising the blonding agent contained in a packaging impermeable to water vapor. Furthermore, the present disclosure relates to a method for blonding human hair. The blonding agent is an anhydrous, powdered cosmetic composition, wherein the cosmetic composition contains at least one oxidizing compound and a mixture of thickening agents.
US11129776B2 Compositions for cosmetic raw material and methods for making the same
The instant invention relates to a composition for cosmetic raw material containing microcapsule containing at least one encapsulated material comprising at least one core and at least one layered coating surrounding said core, and the encapsulated material being at least one reflective particle. The invention further relates to a process for preparing the composition for cosmetic raw material containing microcapsule containing at least one encapsulated material comprising at least one core and at least one layered coating surrounding said core, and the encapsulated material being at least one reflective particle.
US11129773B2 Pressure-regulating vial adaptors
In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.
US11129772B2 Fluid container devices, methods and systems
A drug container assembly for use with a parenteral drug delivery device is disclosed. The container assembly includes a container configured to hold the medication and an intermediate port connector. The port connector may be fixedly coupled to the container and removably coupled to the delivery device in a convenient, reliable, and sealed manner. In use, the port connector may convey the medication from the container to the delivery device for delivery to the patient.
US11129771B2 Intravenous fluid bag with an integrated valve having a seal with a compressed state that permits fluid flow into the bag and a relaxed state preventing fluid flow
An intravenous fluid bag comprising: a primary chamber configured to retain a liquid; a valve in fluid communication with the primary chamber, the valve including a housing, a spike element, and a seal, with the housing surrounding the seal, which surrounds the spike element; the spike element having a first end culminating in a tip, a second end having an inner conduit, and one or more through holes between the tip and the second end in fluid communication with the inner conduit forming part of a continuous liquid passageway in fluid communication with the primary chamber; the seal having a relaxed state preventing fluid flow through the valve, and the seal having a compressed state through which the through holes of the spike element extend allowing fluid flow from a source external the intravenous fluid bag, through the through holes, through the inner conduit, and into the primary chamber.
US11129768B1 Foot-massaging device
The foot-massaging device is a medical device adapted for use with a patient. The foot-massaging device is adapted for use with the left foot and the right foot of the patient. The foot-massaging device is adapted for use with the person lying in a prone position. The foot-massaging device massages, warms and provides therapeutic services to both the left foot and the right foot. The foot-massaging device comprises a chevron, a left foot apparatus, a right foot apparatus, and a control system. The left foot apparatus, the right foot apparatus, and the control system are mounted on the chevron. The left foot apparatus and the right foot apparatus massages, warms and provides electrical stimulation to the left foot and the right foot respectively.
US11129766B2 Flexibly driven robotic hands
Systems and methods for robotic and exoskeleton hands are provided. An exoskeleton hand can include a flexible actuator having a cavity and a reinforcement band. The cavity can be filled with a fluid from a pressure source, forcing the actuator to deform, bend or extend. The fluid that fills the cavity as a driving force can be a gas or liquid, which can be recyclable or disposable.
US11129761B2 Modular adjustable bed system facilitating assembly in a manual, partially-electric, or fully-electric configuration
A bed system includes a fixed frame, a movable frame, and first and second end boards disposed at the head and foot ends of the fixed frame, respectively. The system may be assembled and/or configured such that: a first electric or manual actuator is coupled between the fixed frame assembly and a first linkage assembly of the movable frame assembly for powered or manual movement of a first movable section of the movable frame assembly; a second electric or manual actuator is coupled between the fixed frame assembly and a second linkage assembly for powered or manual movement of a second movable section of the movable frame assembly; and/or a third electric or manual actuator is coupled between the first and second end boards for powered or manual height adjustment of the head and foot ends of the fixed frame assembly.
US11129753B2 Methods and apparatuses for making elastomeric laminates
The present disclosure relates to methods for making elastomeric laminates that may be used as components of absorbent articles. Aspects of the methods for assembling elastomeric laminates may utilize elastic strands supplied from beams that may be joined with first and second substrates, and may be configured to carry out various types of operations, such as bonding and splicing operations.
US11129748B2 Curved eye protection shield for welding protection
A curved eye protection shield for welding protection. The eye protection shield has an electrically switchable darkening filter and a protective cover. The darkening filter has eye facing major inner and outer surfaces, and the protective cover has major inner and outer surfaces. The protective cover is provided for arrangement on the inner surface of the darkening filter. The inner and outer surface of the darkening filter are equidistant, whereas the inner and outer surface of the protective cover are non-equidistant. The invention is advantageous in that it provides an eye protection shield having a minimized refractive power.
US11129747B2 Modifying humidity to glabrous tissue for the treatment of migraine and other conditions
Systems and methods for improving or preventing a condition, such as the treatment of pain syndromes and migraine headaches are disclosed. A method for treating pain can include one or more of the steps including identifying a region of the patient comprising glabrous tissue; positioning the region of the patient comprising glabrous tissue into an enclosed chamber; adjusting the relative humidity of the enclosed chamber sufficient to create a physiologic effect. The method need not involve altering the temperature within the enclosed chamber.
US11129744B2 Systems and methods for providing ostomy faceplates in close proximity with negative pressure wound devices
In general, the present invention is directed to systems and methods for providing ostomy faceplates in proximity to negative pressure wound devices. This may be achieved, for example through the use of an ostomy appliance or faceplate with a non-circular flange for attachment of a bag or pouch. In accordance with some embodiments, this non-circular flange may be substantially “D”-shaped, and/or have at least one substantially straight edge. In some embodiments, the ostomy faceplate may itself be noncircular and/or “D”-shaped; may include a cutting guide for cutting materials used with an NPWD; may contain an asymmetrically located aperture; and/or may comprise one or more tapered edges.
US11129743B2 Set of nose-modelling instruments, production method and a method for modelling the nose
An external modelling method, including applying to a nose of initial external shape F0, at least two modelling instruments I, to guide the growth of the nose cartilage and thus obtain a target final external nose shape Ff when the individual has stopped growing, which differs from a natural external shape Fn, which would be obtained naturally in the absence of intervention. A set of modelling instruments is provided, the successive shapes of which are determined to represent an evolving succession of one or more target intermediate shapes F, from the initial external nose shape F0 through to the target final external shape Ff. A method of producing the modelling instruments is provided, during which method, starting from the initial external nose shape F0, a target final shape Ff and at least one target intermediate shape F are determined. The instruments corresponding to each target shape are manufactured.
US11129737B2 Locking assembly for coupling guidewire to delivery system
A locking assembly for releasably coupling a first elongate member to a second elongate member is provided. The locking assembly can include a first lumen for anchoring the locking assembly to a catheter and a second lumen for releasably retaining a guidewire to the locking assembly. A release member can interface with the locking assembly and apply a force that decouples the guidewire from the locking assembly.
US11129734B2 Ankle-foot prosthesis for automatic adaptation to sloped walking surfaces
An ankle-foot prosthesis includes a foot plate, an ankle frame attached to the foot plate, a yoke pivotally connected to the ankle frame and including a member for attaching to a leg, a damper having a first end connected to the yoke and a second end connected to the ankle frame, and a control mechanism for switching the damper between low and high settings.
US11129733B2 Hip arthroplasty trial systems and associated medical devices, methods, and kits
Hip arthroplasty trial systems and associated medical devices, methods, and kits are described that can be utilized in situ to complete a femoral head trial. An example embodiment of a hip arthroplasty trial system includes a medical device and a femoral stem. The medical device has a head member, a spacer, a shaft, and a locking member. The spacer is disposed within the head member and is moveable from a first position to a second position. The shaft is disposed within the head member and contacts the femoral stem. The shaft is moveable from a first position to a second position. Movement of the shaft from the first position to the second position moves the spacer from its first position to its second position. The locking member is disposed within the head member and releasably attaches the shaft to the head member.
US11129730B2 Spinal fusion cage system with inserter
The present disclosure relates to a spinal fusion impactor tool that includes an attachment means for securing an implant device to the distal end of the tool, a means for adjusting the angle of the distal head relative to the handle to better position the implant for introduction into the implant site, means for remotely releasing the implant device at the distal end and a clamp device on the shaft of the tool to secure tabs, attachments and other devices. The impactor tool is preferably used in conjunction with implantation of an intervertebral fusion cage that is equipped with shims having tabs or other removing means, but may also be used to introduce, for example, an implant, graft, fusion device, wedge or distractor device into any joint space or bony region in preparation for implantation.
US11129726B2 Facet distraction and fusion prosthesis
A facet distraction prosthesis (10, 30) includes an array of facet distraction base elements (12, 32) connected to each other by one or more connector elements (14, 34). A pair of diagonally adjacent base elements (12, 32) are connected to each other by a set of or more connector elements (14, 34) which intersects with another set of one or more connector elements (14, 34) that connects another pair of diagonally adjacent base elements (12, 32). The connector elements (14, 34) are flexible so that the base elements (12, 32) can flex with respect to each other and adapt to a geometry of a facet joint.
US11129724B2 Stemless prosthesis anchor component
A prosthesis assembly is provided that includes a base member (104) that has a helical structure (224) and one or more pathways. The helical structure extends between a first end and a second end. The pathway is accessible from the second end and is directed toward the first end through the helical structure. The pathway is located inward of an outer periphery of the helical structure, e.g., adjacent to an inner periphery of the helical structure. The pathway extends in a space between successive portions of the helical structure. The prosthesis assembly includes a locking device (108) that has a support member and an arm (110) I/O that projects away from the support member. The arm is configured to be disposed in the pathway when the support member is disposed adjacent to the second end of the base member. The arm is disposed through bone in the space between successive portions of the helical structure when the prosthesis assembly is implanted.
US11129722B2 Meniscus prosthetic device selection and implantation methods
Methods of selecting and implanting prosthetic devices for use as a replacement meniscus are disclosed. The selection methods include a pre-implantation selection method and a during-implantation selection method. The pre-implantation selection method includes a direct geometrical matching process, a correlation parameters-based matching process, and a finite element-based matching process. The implant identified by the pre-implantation selection method is then confirmed to be a suitable implant in the during-implantation selection method. Methods of implanting meniscus prosthetic devices are also disclosed.
US11129720B2 Cruciate replacing artificial knee
A knee joint prosthesis is capable of moving between an extended position and a flexion position. The knee joint prosthesis includes a femoral component that is configured to be mounted to a femur, a tibial component that is configured to be mounted to a tibia, a post fixedly connected to one of the femoral component and the tibial component, and a cam recess defined on the other of the femoral component and the tibial component that is configured to be engaged by the post in either the extended position or the flexion position of the knee joint prosthesis. The knee joint prosthesis may also include an artificial ligament that extends between the femoral component and the tibial component. The post and the ligament mimic one of the ACL and PCL.
US11129719B2 Trial radial head implant
A trial orthopedic implant having a plurality of bearing component augments of differing heights, where each augment releasably, slidably connected to the trial implant.
US11129714B2 Hydraulic delivery systems for prosthetic heart valve devices and associated methods
Systems, apparatuses, and methods for treating native heart valves are disclosed herein. A system for delivering a prosthetic device into a heart of a patient includes an elongated catheter body and a delivery capsule. The delivery capsule can be hydraulically driven to deploy at least a portion of a prosthetic heart valve device. The delivery capsule can release the prosthetic heart valve device at a desired treatment site in a patient.
US11129712B2 Prosthetic heart valves with elastic support structures and related methods
Prosthetic heart valves having elastic leaflets and an elastic support structure are described. The support structure can store a load transferred from the leaflets as potential energy and then release it in the form of kinetic energy to exhibit a precursory transition from the closed position to the open position. The support structures can exhibit a sinusoidal movement profile at a base edge during the precursory transition.
US11129711B2 Double component mandrel for electrospun stentless, multi-leaflet valve fabrication
Provided herein is a mandrel for use in electrospinning prosthetic valve devices. Also provided are prosthetic valve devices for implantation in an animal or a human. Methods of making and using the valve devices are also provided herein.
US11129710B2 Prosthetic heart valve having improved commissure supports
A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.
US11129705B2 Sensing apparatus, artificial skin, method of detecting touch, and sensor
A sensing apparatus includes a base substrate; a plurality of sensing units on the base substrate, a respective one of the plurality of sensing units including a first component configured to emit light and a second component configured to detect light; and an elastic layer on a side of the plurality of sensing units distal to the base substrate and configured to undergo a deformation upon a touch, at least a portion of light emitted from the first component being reflected by a surface of the elastic layer. The second component is configured to detect light reflected by the surface of the elastic layer and output a sensing signal, an intensity of which being correlated to a degree of the deformation of the elastic layer at a local position.
US11129703B2 Intraluminal device and method of fixation
An intraluminal device and method of fixation of an intraluminal device at a recipient having an esophagus, a stomach with a cardiac portion and a GE junction between the esophagus and the cardiac portion of the stomach includes deploying the intraluminal device to the recipient. The intraluminal device has a wall defining a cardiac member that is configured to the size and shape of the cardiac portion of the stomach and deployed to the cardiac portion of the stomach and an esophageal member that is configured to the size and shape of a portion of the esophagus and deployed to the esophagus. The intraluminal device having a connector connected with the esophageal portion and cardiac portion and deployed to the GE junction. The wall is fixed to the recipient to resist distal migration of the wall. The fixing includes the wall having a wall characteristic that is configured to facilitate tissue ingrowth. The wall is temporarily fixed to the recipient to resist distal migration of the wall while tissue ingrowth occurs at the wall characteristic.
US11129701B1 Lip implant and associated surgical method
The embodied invention is a lip implant that includes small eyelets on either end of a small diameter rod located inside, and extends beyond, the cosmetic volume of the implant. Sutures connected to eyelets on the rod ends, allow the implant to be pulled into a minimal lip cavity that is created for the implant. The implant is readily positioned by using the sutures. Only two small incisions are needed as well as the creation of a small cavity needed for the implant. The use of the embodied invention is also extended to vein implants to enhance the appearance of veins on arms, legs, or to other surfaces.
US11129699B2 Dental treatment instruments
A dental instrument is configured to reduce user discomfort and increase control over the surgical edge of the instrument. The invention further discloses a dental instrument having a replaceable blade.
US11129697B2 Measuring system and method for measuring an implant-implant situation
The invention relates to a measuring system for measuring an implant-implant situation for planning an implant-supported tooth replacement part supported on at least two implants, comprising a scanning template and the at least two set implants. The scanning template has cut-outs for the individual implants, wherein first markings are arranged on surface regions around the cut-outs.
US11129693B2 Methods of improving dental restoration margins and articles
A method is provided for placing a preformed dental article. The method comprises: providing a preformed dental article; providing an uncured self-supporting dental article having a first shape, wherein the uncured dental article comprises: a polymerizable resin system; at least 50 wt-% of filler; placing the preformed dental article onto a tooth structure such that the uncured dental article is provided at an interface between the preformed dental article and tooth structure; and forming the uncured dental article into a second shape thereby improving the continuity of the interface. Further, a dental article for use at an interface between a dental restoration and tooth structure having a first self-supporting shape are provided in accordance with the invention.
US11129692B2 Bone bed drilling template
A method and device for ensuring better placement of an implant, such as an implant that is affixed via bone bed drilling to a recipient's skull. In particular, the technology comprises an apparatus and method of deploying the same that can lead to an improved goodness of fit of the implant. The apparatus and process of the present disclosure are particularly applicable to affixing auditory prostheses such as cochlear implants. The implant is provided with a template that has the same dimensions as the implant that is to be affixed. This template has a dye-impregnated material on its distal surface that is used during bone bed drilling to identify bony spots that have to be drilled away to get a flat surface and a better alignment of the implant with the bone bed. The template may also be provided in kit form.
US11129687B2 Sheathes for surgical instruments, and related devices and methods
A sheath for a surgical instrument may include a sleeve having a distal end and proximal end, and a retention mechanism at a proximal end portion of the sleeve. The retention mechanism may comprise a sleeve attachment portion configured to be attached to the sleeve at the proximal end portion, and a locking collar extending from the sleeve attachment portion, wherein the locking collar is configured to receive a connector portion of a surgical instrument. The locking collar further may include a locking feature movable between a first configuration, in which the sheath is moveable relative to the surgical instrument, and a second configuration, in which the locking feature is configured to engage with the connector portion to retain the sheath in position on the surgical instrument.
US11129682B2 Medical robot arm apparatus, medical robot arm control system, medical robot arm control method, and program
Provided is a surgical imaging apparatus that includes a multi-link, multi joint structure including a plurality of joints that interconnect a plurality of links to provide the multi-link, multi joint structure with a plurality of degrees of freedom, at least one video camera being disposed on a distal end of the multi-link, multi-joint structure; at least one actuator that drives at least one of the plurality of joints; and circuitry that detects a joint force experienced at the at least one of the plurality of joints in response to an applied external force, and controls the at least one actuator based on the joint force so as to position the video camera.
US11129679B2 Fiber optic tracking system
A fiber optic tracking system includes a light source, a first optical fiber, a second optical fiber, a sensing unit, and a controller operatively coupled to the sensing unit. Each optical fiber includes a plurality of sensing sections and has a fixed sensing point located along its respective length that is fixed relative to tissue. Each optical fiber is configured to receive an optical signal from the light source. The sensing sections are configured to modify the optical signals in response to a deformation of the respective optical fiber. The sensing unit is configured to receive modified optical signals from the first optical fiber and the second optical fiber. The controller is configured to determine locations in a working coordinate system of the fixed sensing points using the modified optical signals and determine a pose of the tissue based on the locations of the fixed sensing points.
US11129677B2 Light based tissue treatment device
A light based treatment device comprises an optical arrangement at a light exit end of an optical fiber. The optical arrangement includes a master oscillator power amplifier based on a semiconductor optical laser and a crystal optical amplifier. In this way, the peak power provided along the optical fiber can be reduced to prevent damage to the optical fiber, while enabling a sufficiently high pulse power to be delivered for tissue treatment.
US11129671B2 Energy control device, treatment system and actuating method of energy control device
A controller carries out a single outputting phase in which only first electric energy is supplied to an electrode, and transitions the single outputting phase to a simultaneous outputting phase in which the first electric energy and second electric energy are simultaneously output and treated target is denatured due to both of a high-frequency current and treatment energy generated in a functioning element. The controller sets a control pattern relating to the treatment energy in the simultaneous outputting phase, based on an impedance at a certain time point in the single outputting phase and/or a variation with time of the impedance in the single outputting phase.
US11129664B2 Systems and methods for delivering energy into a target tissue of a body
An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.
US11129663B2 High-temperature cryosurgery system and methods of using the same
A high temperature cryosurgery system and method of operation comprising a refrigeration assembly, a cryoprobe and a refrigerant wherein the cryoprobe and the refrigeration assembly are fluidly coupled in a closed loop configured to cycle the refrigerant in a fluid state from the refrigeration assembly to the cryoprobe and further configured to cycle the refrigerant in a vapor state from the cryoprobe to the refrigeration assembly. A method for treating cancer tumors and metastatic cancer cells by disrupting the tumor by sequentially or concurrently administering an ablative energy in combination with immunomodulation and/or pharmacological application, in one or more cycles, where the physical disruption is applied at levels sufficient to create the abscopal effect. That effect is generated by stimulating the immune cells in the microenvironment. The tumor is treated in a way permitting the remaining cells or elements in the tumor microenvironment to exert net immune stimulation with also long-term memory cells to fight subsequent appearing tumor in the future. Adding immune modulators injected in situ systemically or embedded in slow releasing means locally or systemically will boost the immune response to the cancer.
US11129662B2 Ablation probe with deployable sensors
The present disclosure relates to a thermal ablation probe device that integrates deployable sensors with a freezing probe or heating probe for use in ablating tissues. The ablation probe includes a longitudinal body including a thermal ablation energy source which may be, e.g., a cryosource or a heat source. The longitudinal body has a proximal end and a distal end terminating at a probe tip; and at least one deployable assembly disposed within the longitudinal body. The deployable assembly includes a flexible and substantially rigid deployment member, and at least one sensor affixed to a distal end of the deployment member. The ablation probe further includes a control mechanism for controlling deployment and retraction of the deployable assembly.
US11129660B2 Electrosurgical generator and methods
The disclosed technology is directed to a RF power generator and feedback control system used to regulate the electrical power delivered to a cutting filament (i.e., a cutting electrode) of an electrosurgical instrument. The electrosurgical instrument uses the delivered energy to form a cutting arc for ablating a tissue mass to access a target tissue therein. The instrument forms a basket-like receptacle around the target tissue to excise the target tissue from the ablated tissue mass. As the instrument forms the receptacle, the length of exposed filament ablating the tissue changes. To this end, the RF power generator described herein is configured to vary the total power delivered during the deployment of the instrument based on a measurement of output power derived from a differential phase angle between a current sense output and a voltage sense output, in some embodiments, to maintain a uniform power density along the length of exposed filament.
US11129659B2 Flow diverter for bone cement delivery systems
A bone cement delivery system includes a plunger configured to selectively displace bone cement from a cement reservoir through an exit port. Additionally, the system includes a flow diverter comprising a diverter inlet, a first diverter outlet, and a second diverter outlet. The system also includes a cannula coupler configured for connection to a delivery cannula for directing the bone cement to a target site, and a drool accumulator defining a drool volume for receiving residual bone cement. The flow diverter includes a valve arranged for selective movement between a first configuration where fluid communication is established between the cement reservoir and the drool volume; and where fluid communication is interrupted between the cement reservoir and the cannula coupler; and a second configuration where fluid communication is established between the cement reservoir and the cannula coupler; and where fluid communication is interrupted between the cement reservoir and the drool volume.
US11129655B2 System and method for bone fusing implants
A bone fusing implant device includes an elongated body extending along a longitudinal direction. The elongated body includes a first segment having an outer surface with cortical threads, a second segment having an outer surface with cancellous threads, a top segment and a bottom segment. The first segment is adjacent to the second segment along the longitudinal direction and is configured to engage a cortical bone with the cortical threads and the second segment is configured to engage a cancellous bone with the cancellous threads. The elongated body has one or more elongated fusing gutters extending along the longitudinal direction on an outer surface of the elongated body covering the first and second segments, a central opening extending along the longitudinal direction through the elongated body's center and one or more through-openings that extend horizontally and intersect with the one or more fusing gutters.
US11129654B2 Adjustable suture-button construct for ankle syndesmosis repair
An adjustable, knotless button/loop construct for fixation of ankle syndesmosis tibio-fibular diastasis and an associated method of ankle repair using the same. The knotless construct comprises a pair of buttons attached to a flexible, continuous, self-cinching, adjustable loop integrated with two splices that are interconnected. The knotless construct is passed through fibular and tibia tunnels and the buttons are secured on the cortical surfaces of tibia and fibula. One of the buttons (for example, an oblong button) is secured on the medial side of the tibia by passing the button and the flexible, adjustable loop though the fibular and tibia tunnels and then flipping and seating the button outside the tibia. The length of the flexible adjustable loop is adjusted so that the second button (for example, a round button) is appropriately secured on the lateral fibula.
US11129651B1 Pop-on-cap assemblies having opposing splay-resisting features and opposing anti-rotation features for spinal surgery
A spinal-surgery system having a rod receiver and/or a cap for use insertion and removal from the receiver. The cap has a generally cylindrical body, a set of opposing splay-resisting flanges, and set of opposing rotation-preventing wings, the flanges extending radially from the body along a first radial line of the body, and the wings extending radially away from the body along a second radial line of the body generally orthogonal to the first radial line. Each cap flange has a proximal-facing cap splay-resisting surface, and a distal-facing cap pop-on surface. Each receiver proximal protrusion has a proximal-facing sloped receiver pop-on surface, and a distal-facing sloped receiver splay-resisting surface. The receiver pop-on surfaces are spaced such that each cap pop-on surface contacts a respective receiver pop-on surface when the cap is centered, with the cap wings aligned between receiver arms, and moved distally to contact the receiver.
US11129650B1 Spinal plate
The present invention provides a spinal plate which is used to perform fixation surgery on a spine in orthopedic surgery and neurosurgery. According to the present invention, a rotation device and a locking device may be installed so as to be used by fixing any one or more of longitudinal ends of the plate with being rotated at any angle, thereby allowing a doctor to modify a shape of the spinal plate to the shape desired by the doctor, and to perform the surgery by coping with various spin shapes of patients. In addition, according to the present invention, since the shape of the spinal plate may be rotated at any angle, it is possible to cope with various spin shapes of the patients.
US11129649B2 Joint fusion implant and methods
An implant for fusing a joint between first and second bone portions. The implant includes a screw member, and a washer polyaxially rotatable relative to the screw member. The screw member includes a head, a lag zone, and a threaded engagement zone. The implant includes a fusion zone for joint compression, extending from the washer to the proximal end of the engagement zone. Fenestrations may be present in the fusion zone. The length of the fusion zone ranges from about 10 mm to about 37 mm. Different surface finishes including roughened and non-roughened may be applied selectively to selected portions of the implant. In an embodiment, the joint is a sacro-iliac joint, and upon implantation the implant extends from the exterior of the ilium, across the joint and into the sacral vertebral body. Instrumentation and methods for preparing the joint and implanting the implant are disclosed.
US11129648B2 Spinal stabilizing and guiding fixation system
In one example, an implant holder supports a guiding connector that attaches to a vertebrae and that secures to an elongated support member by a cable tie. The implant holder has a handle portion that has a shaft that extends between proximal and distal ends of the handle portion. The distal end of the handle portion can be positioned proximate to the guiding connector when the guiding connector is supported by the implant holder. The implant holder has at least one holder defining a channel therethrough that receives the shaft of the handle portion such that the at least one holder is slidable along the shaft. The at least one holder secures the cable tie and at least one wing of the guiding connector to the handle portion.
US11129646B2 Medical implant threaded plug having a start structure with symmetrically shaped concave and convex leading surfaces
A medical implant assembly including a receiver and a plug. The receiver can be configured with first and second arms having helically wound thread extending up to a top surface thereof. The plug being at least partially threadably positioned within the channel. The plug having an axis of rotation and a continuously helically wound thread form. The continuously helically wound thread form having a start structure and an upper surface extending between a root and a crest of the continuously helically wound thread form. The start structure having a leading face extending below the upper surface. The leading face including a partial concave surface adjacent the root and a partial convex surface adjacent the crest. The partial concave and partial convex surfaces each defined by a radius of curvature that can be substantially equal with respect to each other.
US11129645B2 Methods of securing a fastener
Embodiments may include an attachable fastener, which may include a bondable material that may be secured to the end of an end effector. Vibration may be tuned to occur at a distal end of the fastener. Accordingly, the fastener may be used to generate heat at a distal point of contact. If the contact surface contains bondable material, that material may be softened. If the fastener includes bondable material at the point of contact, that material may also be softened by heat produced by vibration at the contact area. A hard implant or another polymeric material may function as the anvil.
US11129643B2 Neurosurgical apparatus
A neurosurgical apparatus includes a guide device and a neurosurgical instrument is disclosed. The guide device includes a tube for insertion into the brain and a head attached to the proximal end of the tube for affixing the guide device to a hole formed in the skull. The head has a passageway therethrough in communication with the bore of the tube such that the bore of the tube and the passageway through the head define an internal channel through which a neurosurgical instrument can be passed into the brain of the subject. The neurosurgical instrument is for insertion to a desired brain target through the internal channel of the guide device. The apparatus includes one or more sealing elements for providing a fluid tight seal between the internal channel of the guide device and the exterior of the neurosurgical instrument to prevent fluid leakage from guide tube.
US11129636B2 Surgical instruments comprising an articulation drive that provides for high articulation angles
A surgical instrument is disclosed comprising a shaft, an end effector, and an articulation joint rotatably connecting the end effector to the shaft. The surgical instrument further comprises an articulation drive system configured to permit high degrees of articulation.
US11129634B2 Surgical instrument with rotary drive selectively actuating multiple end effector functions
Surgical instruments having a rotary drive that can selectively actuate multiple end effector functions are described herein. In at least one embodiment, a surgical instrument includes a shaft, an end effector coupled to the shaft, a rotatable drive shaft coaxially disposed within an inner lumen of the shaft, and a plurality of selectively engageable clutches configured to transfer torque from the rotatable drive shaft to the end effector. Each of the clutches is configured to convert the rotation of the drive shaft into one of a plurality of movements of the end effector relative to the outer shaft.
US11129622B2 Devices and methods for occlusion of an atrial appendage
Various aspects of the present disclosure are directed toward apparatuses, methods, and systems as relating to occlusion. In certain instances, the apparatuses, methods, and systems may include a device for placement in vessels, appendages, and openings in a body. The device may include a unitary frame having a face portion that includes a center frame portion a plurality of elongate members.
US11129621B2 Devices, systems, and methods for the treatment of vascular defects
Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, includes an occlusive device comprising a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising a first end portion, a second end portion, and a length extending between the first and second end portions, and a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges. The mesh may have a predetermined shape in the deployed state in which (a) the mesh is curved along its width, (b) the mesh is curved along its length, and (c) the mesh has an undulating contour across at least a portion of one or both of its length or its width. The mesh is configured to be positioned within the aneurysm in the deployed state such that the mesh extends over the neck of the aneurysm.
US11129620B2 Adapter assembly including a removable trocar assembly
An adapter assembly for connecting a loading unit to a handle assembly is provided. The adapter assembly includes a sleeve, a removable trocar assembly releasably securable with the sleeve, and a locking assembly configured to releasably secure the trocar assembly within the sleeve. The locking assembly includes first and second button members and corresponding first and second locking members for releasably securing the trocar assembly.
US11129617B2 Tissue anchor for securing tissue layers
Tissue anchors comprise a woven filament braid body having an elongated tubular configuration and a foreshortened configuration where proximal and distal ends of the body expand radially into double-walled flange structures while leaving a cylindrical saddle region therebetween. The tissue anchors are deployed through penetrations between adjacent tissue layers, where the flanges engage the outer surfaces of the tissue layers and the saddle region resides within the tissue penetrations.
US11129616B2 Surgical stapling system
A surgical stapling system comprising a robotic interface and a surgical stapling attachment assembly configured to be attached to the robotic interface is disclosed. The robotic interface comprises motor-driven output drives. The surgical stapling attachment assembly comprises a closure member configured to be actuated by one of the motor-driven output drives, a firing bar configured to be actuated by another one of the motor-driven output drives, an end effector, and a shaft comprising an articulation joint. The end effector comprises a first jaw, a second jaw, and a pivot pin coupling the first jaw and the second jaw and defining a pivot axis. The closure member is actuatable through a closure stroke to move the second jaw relative to the first jaw.
US11129610B2 Needle harvesting devices, systems and methods
A suturing system including an elongate distal member, an elongate proximal member proximal the elongate distal member, and a needle guide disposed between the elongate distal member and the elongate proximal member. A plurality of needles with a needle tip of each needle of the plurality of needles are orientated generally proximally toward a single opening in a distal end of the elongate proximal member. When the needle tip of each of the plurality of needles is at least partially disposed within the single opening, a portion of each needle of the plurality of needles, proximal a distal end of the needle guide, being radially separated by a distance less than a diameter of the elongated proximal member.
US11129607B2 Anchored loop-in-loop suture anchor
A system and method for securing a target body to a bone mass with a loop-in-loop suture anchor. The system generally includes suture material passing through a substrate (e.g., suture anchor). The suture material includes a splice that allows the suture material to be passed through the splice and around a target body, ultimately creating three loops in the suture material. By tensioning the loops and/or ends of the suture material, the loops bring the target body into a desired position relative to the bone mass and secure it in that position.
US11129606B2 Method and apparatus for intercondylar notch distraction knee arthroplasty
A method and apparatus for distracting a joint during a procedure are disclosed. The apparatus can include bone engaging portions and an articulating bearing. The bone engaging portions can engage the bone and then the articulating portions can allow joint motion. The method can use the apparatus to perform a procedure with the apparatus.
US11129597B2 Adaptive medical image transmission device and method
The present invention relates to an adaptive medical image transmission device and method which consider communication state and residual power. The adaptive medical image transmission method induces an image receiving device to post-process a result of medical image processing performed by a medical image transmission device by: receiving medical image data by means of a probe; sensing communication throughput indicative of a communication state between the image transmission device and the image receiving device; variably determining a data rate required to transmit data on the basis of a preset data rate based on the sensed communication throughput; performing medical image processing by selecting a signal path which satisfies the determined data rate with respect to the medical image data; and transmitting the result of the medical image processing to the image receiving device according to the determined data rate.
US11129585B2 Computed tomography system and patient table including a contactless transfer of electrical signals
A computer tomography installation having contactless data signal transmission is provided. The device includes a conductor element that is longitudinally slit coaxial, at least one high-frequency transmitting unit that feeds a high-frequency carrier signal modulated with a data signal to be transmitted into the conductor element, and at least one longitudinally slit coaxial coupling conductor element that is configured to receive the emitted modulated high-frequency carrier signal from the near field of the conductor element. The device also includes a high-frequency receiving unit that is electrically connected to the coupling conductor element and is configured to extract the data signal from the received modulated high-frequency carrier signal. The conductor element and the coupling conductor element are arranged to be movable relative to each other. The conductor element is arranged on a rotatable gantry part, and the coupling conductor element is arranged on a stationary gantry part.
US11129583B2 Apparatus and system for rule based visualization of digital breast tomosynthesis and other volumetric images
The invention provides, in some aspects, a system for implementing a rule derived basis to display volumetric image sets. In various embodiments of the invention, the selection of the images to be displayed, the generation of the 3-D volumetric image from measured 2-D images including the rendering parameters and styles, the choice of viewing directions and 2-D projection images based on the viewing directions, the layout of the projection images, and the formation of a video can be determined using a rule derived basis. In an embodiment of the present invention, the user is presented with sequential images making up a video displayed based on their preferences without having to first manually adjust parameters. The present invention allows for novel ways of viewing such images to detect microcalcifications and obstructions when reviewing Digital Breast Tomosynthesis and other volumetric mammography images.
US11129580B2 Intraoral sensor and method for producing intraoral sensor
An intraoral sensor includes an image sensor, an FOP, a scintillator, a case, and a signal cable. The FOP includes a first main surface, a second main surface, and a plurality of lateral surfaces. The first main surface and the second main surface have a polygonal shape. An edge of the second main surface is constituted by a plurality of corner portions, and a plurality of side portions. The scintillator is provided on the second main surface and the plurality of lateral surfaces in such a manner that a second corner portion out of the plurality of corner portions and a second ridge portion are exposed. The second corner portion located on a second direction side opposite to a first direction in which the signal cable extending beyond, and the second ridge portion constituted by the lateral surfaces adjacent to the second corner portion adjacent to each other.
US11129571B2 Cardiac waveform sensing
A sensing device that may include sensing elements that elements comprise a first sensing element, a second sensing element; wherein each sensing element comprises one or more piezoresistive materials; and a sensing circuit that is coupled to the sensing elements, wherein the sensing circuit is configured to sense a resistance of the first sensing element and of the second sensing element, and to determine, based on the resistance of the first sensing element and of the second sensing element, a first parameter of a cardiac waveform of a living being, wherein the cardiac waveform (a) is sensed by the first sensing element, and (ii) is not sensed by the second sensing element.
US11129567B2 Portable nystagmus examination device
A portable nystagmus examination device includes: a main body which is provided in the form of goggles and comes into contact with the face of a subject so that the visual field of the subject is blocked from the outside; a camera unit which is provided on the inner side of the main body and captures eyeball image information on the subject; a monitor unit which is provided on the outer side of the main body and displays, to a user, the eyeball image information on the subject captured through the camera unit; and a control unit which is provided in the main body, collects the eyeball image information on the subject captured by the camera unit, and controls the monitor unit to output the eyeball image information. Thus, the user can perform the nystagmus examination regardless of a place.
US11129565B2 Method for representations of network-dependent features of the hemoglobin signal in living tissues for detection of breast cancer and other applications
A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb−oxyHb).
US11129564B2 Methods for aiding in diagnosing and evaluating a mild traumatic brain injury in a human subject using cardiac troponin I
Disclosed herein are methods that aid in the diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild or moderate, severe, or moderate to severe traumatic brain injury (TBI), using cTnI. Also disclosed are methods for determining whether to perform a head computerized tomography on a subject by detecting levels of cTnI. Finally, also disclosed are methods of outcome in subjects suffering from a mild TBI.
US11129563B2 Eye-mountable device with muscle sensor
An ophthalmic device includes an enclosure, an electromyography sensor, and a controller. The enclosure is configured to mount in or on an eye. The enclosure further includes a first material and a second material disposed within the first material. The electromyography sensor is adapted to measure electrical activity of a muscle of the eye proximate to a first annular region of the ophthalmic device when the ophthalmic device is mounted in or on the eye. The electromyography sensor includes a first electrode and a second electrode, each positioned within the first annular region between the first material and at least a portion of the second material. The controller, coupled to the electromyography sensor, stores instructions that when executed causes the ophthalmic device to perform operations including acquiring a first signal representative of the electrical activity of the muscle by measuring the electrical activity with the electromyography sensor.
US11129561B2 Modular device and method for analog electroencephalography synchronization with oscillating electrical light-related events, and motor behaviors
This invention relates to a device that is intended to synchronize electroencephalograms (EEGs), recorded by any digital equipment, to physical events (sensorial, visual or auditory stimuli) and behavioral events (motor response, vocal response), in order to allow EEG signal mediation for the purpose of visualizing Evoked Potentials or Event-Related Potentials, which are important research subjects in the neurosciences and clinical investigations into neurological and psychiatric pathologies. This invention allows any digital EEG device to be transformed into equipment that can record Evoked Potentials. This invention also provides a method for analog synchronization of EEGs with oscillating electric light-related events and motor behaviors.
US11129560B2 Systems and methods for filtering ECG artifacts
Systems and methods of processing raw electrocardiogram (ECG) waveform data of a patient into estimated real-time ECG waveform data. The method includes sensing at least one physical non-cardiac influence on the raw ECG waveform data, constructing a time domain computer model of the at least one physical, non-cardiac influence on the raw ECG waveform data, and adaptively filtering the raw ECG waveform data in the time domain using the constructed time domain computer model of the at least one physical non-cardiac influence on the raw ECG waveform data to form the estimated real-time ECG waveform data. The system can include an ECG device for collecting raw ECG waveform data, at least two ECG electrodes positioned on the patient and electrically coupled to the ECG device, and a processor coupled to the ECG device and configured to compute a time domain model of an artifact created by chest compressions.
US11129552B2 Estimation method, information processing apparatus, and non-transitory computer-readable storage medium for estimating motion of animal
An estimation method performed by a computer includes: executing a first identifying process that includes identifying a candidate for a limb having a problem by evaluating left and right balance at the time of movement based on measurement data of a motion sensor attached to an animal moving on four limbs, and executing a second identifying process that includes identifying the limb having a problem among the limbs which are considered as the candidates for a limb having a problem based on a detection result of a nutation movement by detecting the nutation movement from the measurement data.
US11129551B2 Method for providing age-related gait motion trasnformation based on biomechanical observations and an appratus using it
An apparatus for motion transformation according to an embodiment of the present disclosure includes a basic data input unit through which basic motion data is inputted, a pre-processing unit which acquires a parameter through pre-processing of the inputted basic motion data, a motion transformation unit which performs biomechanical observations-based gait motion transformation processing based on the pre-processed parameter and age input information, and an output unit which outputs the transformation processed motion.
US11129548B2 Method, apparatus, and computer readable medium for generating a set of recommended orthotic products
In an embodiment, the present invention is an apparatus, comprising: a foot mat; a depth sensing camera; an elevated foot platform that reduces or prevents rotational movement of a foot; a processor in communication with the depth sensing camera, the processor further configured to calculate the circumference of a user's leg based on data from the depth sensing camera while the user has one foot on the foot mat and one foot on the elevated foot platform, the processor further configured to select a recommended product for the user's knee or ankle from among a set of pre-manufactured candidate products for knees or ankles based at least in part upon the leg circumference of the user; and an output device to display information received from the processor, the information identifying the recommended product to the user.
US11129546B1 Portable unit for metabolic analysis
A portable unit for metabolic analysis includes a manifold in fluid communication with a mouth of a test subject. A conduit extends from the manifold and defines a flow channel through which the breaths of the test subject travels. A carbon dioxide sensor is attached to the conduit. The carbon dioxide sensor includes an intermediate support housing enclosing a volume disposed along the flow channel to define a first part of the flow channel, an inner support housing attached to a first side of the intermediate support housing, a plurality of IR LEDs mounted to an interior surface of the inner support housing, an outer support housing attached to a second side of the intermediate support housing, and a photodetector attached to the outer support housing. The photodetector faces the flow channel and receives IR radiation emitted by the plurality of LEDs.
US11129545B1 Systems and methods for detecting alcohol, acetone, and carbon monoxide in breath
A breath collection device can detect changes associated with pathogenesis of a disease, such as COVID-19, including biomarkers of immune response for respiratory symptoms, central nervous system injury, and/or peripheral nervous system injury in user breath and/or odor. The breath collection device can detect concentrations of alcohol, acetone, and carbon monoxide in user breath samples. A breath sample can be received in an internal bladder of the device for sensor analysis. Concentrations of alcohol, acetone, and carbon monoxide can be determined by calibrated calculation. A detection method for alcohol, acetone, and carbon monoxide can provide a non-invasive, rapid, and selective detection of gases in a variety of applications in virus detection as well as agricultural and homeland security.
US11129543B2 Soft tissue matrix characterization using stretched exponential relaxation modeling
A process for more sensitive characterization of tissue composition for generating a quantitative MRI (qMRI) map and corresponding delta analysis. Intervertebral disc degeneration (IVDD), resulting in the depletion of hydrophilic glycosaminoglycans (GAGs) located in the nucleus pulposus (NP), can lead to debilitating neck and back pain. Magnetic Resonance Imaging (MRI) is a promising means of IVD assessment due to the correlation between GAG content and MRI relaxation values. T1 and T2 relaxation data were obtained from healthy cervical IVDs, and relaxation data was modeled using both conventional and stretched exponential (SE) decays. Normalized histograms of the resultant quantitative MRI (qMRI) maps were fit with stable distributions. SE models fit relaxation behavior with lower error compared to monoexponential models, indicating anomalous relaxation behavior in healthy IVDs. SE model parameters T1 and T1 increased with IVD segment, while conventional monoexponential measures did not vary. The improved model fit and correlation between both SE T1 and T1 with IVD level suggests these parameters are more sensitive biomarkers for detection of GAG content variation.
US11129541B2 Method for recording diagnostic measurement data of a head of an examination object in head imaging via a magnetic resonance device
A method is proposed for recording diagnostic measurement data of a head of an examination object in head imaging via a magnetic resonance device. The method comprises performing an overview scan of the head of the examination object, wherein overview measurement data is acquired in the overview scan and performing various diagnostic scans of the head of the examination object based on the acquired overview measurement data, wherein diagnostic measurement data is acquired in the various diagnostic scans.
US11129539B2 Pulse measuring device and control method thereof
A pulse measuring device includes: an image acquisition unit that acquires plural pieces of time-series photographed image data obtained by photographing a living body; an image processor that generates plural pieces of transformed image data corresponding to the plural pieces of photographed image data by performing a multiple resolution analysis on each of the plural pieces of photographed image data a plurality of times, each of the plural pieces of photographed image data being decomposed into a high-resolution component and a low-resolution component on the multiple resolution analysis; and a pulse measuring unit that calculates a feature quantity indicating luminance of a predetermined area in each of the plural pieces of transformed image data, calculates a variation period of the feature quantity by analyzing time-series data of the feature quantity, and calculates a pulse of the living body based on the variation period of the feature quantity.
US11129537B2 Body-worn sensor for characterizing patients with heart failure
The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.
US11129534B2 Sedentary period detection utilizing a wearable electronic device
Systems and methods for determining a sedentary state of a user are described. Sensor data is collected and analyzed to calculate metabolic equivalent of task (MET) measures for a plurality of moments of interest. Based on the MET measures and a time period for which the MET measures exceed a threshold value, it is determined whether the user is in a sedentary state. If the user is in the sedentary state, the user is provided a notification to encourage the user to perform a non-sedentary activity.
US11129526B2 Devices, method, and computer programs for determining the refraction of the eye
A device and computer program for determining the spherocylindrical refraction of an eye are disclosed. A component having adjustable optics is provided, the refractive power of which can be adjusted via a refractive power adjustment device. The spherocylindrical refraction is then determined from the adjustment of the refractive power adjustment device at different orientations of a typical direction of the optics or a typical direction of eye test characters.
US11129522B2 Method and measurement system for optically measuring an object
The invention relates to a measurement system for optically measuring an object, comprising a dental camera and an optical attachment. In this case the optical attachment comprises at least one lens, which is shaped and arranged in such a way that the optical attachment has a negative focal length so that a measurement field or a measurement volume of the dental camera is enlarged by the optical attachment.
US11129521B2 Optics for video camera on a surgical visualization system
A surgical device includes a plurality of cameras integrated therein. The view of each of the plurality of cameras can be integrated together to provide a composite image. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the composite image generated by the plurality of cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as transparent on the composite image. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices.
US11129518B2 Portable system and method for position and orientation of remote objects
The present invention describes an electromagnetically positioning system, which can measure a position and orientation of a remote object in an isolated targeted examination area with time. Specifically, the remote object is a remote miniaturized examination device. During the location process, both the electromagnetically positioning system and the remote miniaturized examination device can have expected or unexpected, controlled and can-not-be-controlled movement. By implementing the electromagnetically positioning system, disclosed herein, position and orientation information of the remote miniaturized examination device can be linked with time, any information collected by the remote miniaturized examination device, for example, the photo images collected, can be associated kinetically with time and positioning information of the examination device, when the remote miniaturized examination device travels inside an isolated target examination area.
US11129515B1 Arthropod prevention footwear mat assembly
A footwear mat assembly for preventing arthropods from entering footwear stored thereon includes a base including a base top surface including a footwear storage location adapted to receive a pair of footwear, and a raised barrier including a barrier bottom surface adhesively and removably secured to the base top surface, a barrier top surface carrying an arthropod-securing adhesive composition layer, and a barrier inner perimeter defining an opening adapted to receive the pair of footwear therethrough for placement on the footwear storage location.
US11129513B2 Scrub glove for cleaning various articles
A scrub glove (G′) has an inner layer (IL) fitting over a wearer' thumb, fingers, palm, and back of their hand, the wearer's wrist and a portion of their forearm. The glove further has an outer layer (OL) of an abrasive, woven mesh material formed to fit over the inner layer and enclosing the wearer's thumb, fingers, palm, the back of their hand, and their wrist. A band (D) fits over an open end of the outer layer where it fits over the open end and a cuff portion of the inner layer and is permanently secured to both the inner and outer layers. While the outer layer fits over the inner layer, it does not adhere to the inner layer whereby when the glove is used fin cleaning, the outer layer is free to move separately from the inner layer.
US11129509B2 Robot cleaner
There is provided a robot cleaner having an improved dust-collecting capability and an improved suction force and capable of being manufactured in a small size. The robot cleaner includes a main body comprising a fan motor and having a suction port provided in one side thereof; a plurality of cyclone units configured to separate foreign substances in air suctioned through the suction port; and a plurality of suction flow paths connecting the plurality of cyclone units and the suction port.
US11129507B2 Roller cover toilet system and method
The roller cover toilet system provides users with a portable roll-on cover for public toilets designed to keep the seat surface sanitary while sitting. The device features a dustpan-like carrying system designed to house the roll of covers. It allows users to simply roller the cover over the seat and apply it via a light adhesive, ensuring the cover remains stable as the user sits. The device prevents germs and bacteria from being contracted, ensuring the user stays clean even while using a public toilet. The device eliminates the need to use flimsy paper covers commonly found in public restrooms.
US11129506B2 Removable toilet seat system for a walker
A removable toilet seat system for a walker, including a seat portion removably connected to at least a portion of the walker to facilitate a user being disposed thereupon, and at least one seat-holding tab rotatably disposed on at least a portion of the walker to move from retracted in a first position to at least partially extracted in a second position, such that the seat portion is prevented from falling in response to a bottom surface of the seat portion contacting the at least one seat-holding tab.
US11129505B2 Hand dryer having managed air flow
A method and apparatus for drying objects in low-volume enclosed spaces is disclosed. In one embodiment, the apparatus is a hand dryer that comprises a dryer cavity including an input port, an exhaust port, and an opening for insertion of a hand having moisture thereon, an air channel, pneumatically coupling the exhaust port of the dryer cavity to the input port of the dryer cavity, the air channel substantially isolated from an interior volume of the lavatory, and a blower, communicatively coupled to the air channel, for moving air through the air channel and the dryer cavity.
US11129503B2 Abrasive hygiene apparatus and method of use
An abrasive non-pliable hygiene apparatus for smoothing a foot and method of use. The apparatus includes an abrasion sheet, frame, and engagement sheet. The abrasion sheet is composed of a non-pliable, corrosion-resistant material with a roughened top surface designed to increase abrasion efficiency between the sheet and an epidermal surface of a foot. The abrasion sheet also has bracketing members designed to engage the frame. The frame has ridge structures designed to retain the abrasion sheet and allow for user grip. Attached to the bottom of the frame, the engagement sheet facilitates friction, retaining the placement of the apparatus during use. The frame and abrasion sheet may be one structure, having at least one additional channel disposed along a side, allowing other abrasion sheets to be attached thereto.
US11129502B1 Touchless sanitizing apparatus
The present disclosure refers to a touchless and motion-sensing hand sanitizing dispenser that also engages a switch. In some embodiments the hand-sanitizing dispenser functions as a door-opening pushbutton for an automatic door system. The embodiment may be used with existing systems or configured for new installations.
US11129501B2 Cutting board
A cutting board is configured to be suspended above a sink basin. The cutting board includes a top, cutting surface, and a bottom surface opposite the top surface. The cutting board also includes a bevel, an upper ledge, and a bumper. The bevel is disposed along a first edge of the bottom surface. The upper ledge extends outwardly beyond the bevel to support the cutting board along a rim of the sink or countertop. The bumper is disposed on the bevel and engages with the sink to prevent movement of the cutting board in one direction. The cutting board is configured to be used in both a mounted configuration above a basin of the sink and an unmounted configuration on a flat surface away from the sink.
US11129497B2 Baked good handling system
A baked goods handling system includes a holding cabinet operable to create a controlled environment therein. A dispenser receives a baked good from the holding cabinet and directs the baked good away from the holding cabinet. A treatment device receives the baked good from the dispenser to perform a treatment on the baked good.
US11129496B2 Grill grate cleaner and oiler
A device for cleaning and oiling grill grates including a roller fashioned from an absorbent material rotatably mounted to a head plate, which in turn is mounted to a handle. The roller is used to apply cleaning or seasoning oil to grill grates. The plate includes a scraping element for scouring grill grates and an aperture through which a user may apply oil to the roller. The absorbent material may alternatively be mounted as a rectangular pad rather than a roller. A bottle opener attached to the handle of the device allows for the device to be conveniently hung and stored in a downward position.
US11129490B2 Beverage-making apparatus
A beverage-making apparatus includes: an ingredient package accommodation portion. The ingredient package accommodation portion includes: an ingredient package accommodation body including a plurality of ingredient package receiving parts configured to accommodate a plurality of ingredient packages; and an ingredient package accommodation cover configured to couple with and cover the ingredient package accommodation body and secure the plurality of ingredient packages in the ingredient package accommodation portion. Each of the plurality of ingredient package receiving parts, which is configured to accommodate a corresponding ingredient package among the plurality of ingredient packages, includes: at least one discharge channel configured to discharge contents of the ingredient package provided in the ingredient package receiving part, and at least one water supply channel configured to supply water to the ingredient package provided in the ingredient package receiving part.
US11129488B1 Single-serving communion container
The single-serving communion container comprises a fluid container filled with grape juice. The fluid container may be cross-shaped and may be opened during a religious service so that the grape juice may be consumed. The single-serving communion container may further comprise a communion wafer that may be coupled, either directly or indirectly, to the fluid container. The single-serving communion container may further comprise a decorative holder. The decorative holder may be a figurine that holds the fluid container in a non-horizontal position. The figurine may represent a lamb where a leg of the lamb is lifted and wraps around the upright of the fluid container to hold the fluid container in position.
US11129487B2 Theft-resistant deposit box
A wall mount deposit box is provided. A housing includes a front side and a back side. A rotatable content deposit includes a content delivery door and an inner panel affixed on a proximate end at an angle to a bottom of the content delivery door, and is pivotably attached to the front side of the housing. A content slot is formed as an opening within a front surface of the housing when the rotatable content deposit is in a fully open position allowing content to be deposited through the opening over each of the inner panel and the safety arm. A content retrieval door is located below the rotatable content deposit and is pivotably attached to the front side of the housing.
US11129486B2 Combination pillow and sleeping bag or blanket or comforter
A combination pillow and sleeping bag is described. The combination pillow and sleeping bag is configurable between a first configuration and a second configuration. The combination pillow and sleeping bag includes a first pillow portion and a second pillow portion detachably coupled to the first pillow portion. The second pillow portion defines a cavity. The combination pillow and sleeping bag also includes a sleeping bag having a first end coupled to the first pillow portion and a second end coupled to the second pillow portion. When in the first configuration, the first and second pillow portions are coupled together and the sleeping bag is positioned within the cavity of the second pillow portion. When in the second configuration, the first and second pillow portions are detached from one another and spaced apart such that the sleeping bag extends between the first and second pillow portions.
US11129481B2 Inflatable mattress with air leak repair hose
An air leak repair hose for inflatable air mattress, particularly when the hose or tubing system, or its fittings, break because of forceful handling, but can be repaired through the application of a supplemental hose to the remaining portion of any broke fitting, or glued in place within the opening into the air chamber of the mattress, with a new fitting applied to the opposite end of the segment of the supplemental hose, that can be connected with the air pump, in preparation for refilling of the air mattress(s) to the firmness desired by the user.
US11129480B2 Footrest for chair and armchair
A footrest for a chair or an armchair, includes a support platform for the feet of a user of said chair. Said platform is configured to be rotatably fastened to a leg of the chair or armchair, enabling the rotational movement of said platform in a horizontal plane. The platform includes at least one wheel which serves as a support on the ground, preventing the feet from being loaded on the cantilevered platform. In this manner, the footrest moves with the chair, always being available for the user, regardless of whether the chair moves, being able to be retracted underneath the legs of said chair when the platform is not being used by the user.
US11129478B2 Travel pillow
The present invention discloses a U-shaped travel pillow having a base cushion and raised cushion fixed to the top side of the base cushion. The inner peripheral walls of the base and raised cushions are mutually flush, while the rear walls are mutually flush and substantially flat for better contact with flat surfaces, such as a headrest, seat, or chair. Furthermore, the rear wall of the raised cushion is thinner than the sides, providing more liberty to adjust head position by easily adapting to the shape of the headrest, seat or chair. A removable cover is adapted to cover the base and raised cushions, while a drawstring with an adjustable cinch mechanism can be used for adjusting the travel pillow around the neck.
US11129471B1 Mobile computer workstation
The mobile computer workstation is a cart. The mobile computer workstation is configured for use with a computer. The mobile computer workstation forms a mobile station on which the computer is placed. The mobile computer workstation allows the computer readily moved between locations without requiring the disassembly and assembly of the various components of the computer. The elevation of the superior surface of the mobile computer workstation is adjustable such that the computer can be used while standing or sitting. The mobile computer workstation comprises a pedestal, a telescopic master stanchion, and a pivoting desk. The telescopic master stanchion attaches the pedestal to the pivoting desk. The pivoting desk forms the working horizontal surface of the mobile computer workstation. The pedestal: a) is a rolling structure used to move the computer; and, b) stores the elements of the computer not associated with interface functions with a user.
US11129468B2 Cleaning device having a hood with a sweeper and an air knife
A cleaning device including a covering hood having a lower surface facing a surface to be cleaned and an inlet on an upper surface thereof, through which contaminants are sucked; an air knife provided on a circumference of the covering hood and having an outlet for spraying high pressure air to the surface to be cleaned; a sweeper installed inside the covering hood and rotated by a driving motor to guide foreign objects swept away from the surface to be cleaned and contaminants floated by the high pressure air injection of the air knife to the inlet; a rotary member including a shaft passing through a circumferential surface of the covering hood and the air knife, and a rotary knob coupled to one end of the shaft to rotate the air knife to adjust an air spray angle.
US11129465B1 Telescoping arrangement with illuminable rings
An arm wearable apparatus includes a telescoping arrangement having a plurality of sections, a user interface system that removably attaches the telescoping arrangement with an arm of a wearer, and a plurality of illuminable rings. Each ring of the plurality of illuminable rings is attached with a respective section of the plurality of sections and has an inner diameter such that the plurality of illuminable rings form an opening to receive the arm when the telescoping arrangement is in a retracted configuration. At least some of the plurality of illuminable rings are arranged beyond an extent of the arm when the telescoping arrangement is in an extended configuration.
US11129462B2 Container with a brush applicator
A combination container and applicator for a fluid includes a container having a top end open to an internal volume that has a tapered floor. A cap adapted to engage the top end has a brush applicator projecting downwardly therefrom into the internal volume of the container. The brush applicator includes a brush and a sheath, the brush extending beyond the sheath when the brush applicator is in the extended position, and the brush retracting fully inside the sheath when the brush applicator is in the retracted position. The cap includes a brush extension mechanism that is adapted to move the brush applicator between a retracted portion, such that the brush and brush applicator do not contact the floor of the container when the cap is engaged with the container, and an extended position such that the brush is able to reach all areas of the floor of the container.
US11129461B2 Brush integrated capsule with film-forming polymer for nail polishing
A capsule integrated with a nail polish applying element for usage by a nail polish application apparatus comprising a capsule compartment and a pressure applying element, the capsule comprising a container defining a reservoir containing nail polish fluid, the container comprising an upper face with an opening sealed with a sliding gasket and a bottom face, wherein a volume of the reservoir is reduced and an internal pressure is built in the reservoir when pressure application slides the sliding gasket towards the bottom face, and a container housing comprising a body portion shaped to receive and accommodate the container, one or more conveying tunnels having a proximal end mechanically fixated to a bottom side of the body portion and a nail polish applying element mounted to receive the nail polish fluid from a distal end of the conveying tunnel(s) for applying the nail polish fluid on a nail surface.
US11129460B2 Opening/closing nozzle of discharge pump for cosmetic container
An opening/closing nozzle of a discharge pump for a cosmetic container is configured such that it is advantageous in that inflow of air into a nozzle of the cosmetic container can be prevented such that not only degeneration of the content and hardening of the content inside the nozzle, which would otherwise occur if air flows into the nozzle, can be prevented, but the reliability of the product can also be improved.
US11129456B2 Rollable luggage assembly
A rollable luggage assembly for piggybacking a second suitcase on a first suitcase includes a plurality of first rollers that is coupled to a bottom of the first suitcase. A first handle is selectively extensible from the first suitcase so that the first handle is positioned above and perpendicular to a top of the first suitcase. The first handle is configured to be grasped in a hand of a user to urge the first suitcase to roll across a surface. A plate, which is coupled to and is selectively extensible from the bottom of the first suitcase, is selectively positionable in a retracted configuration, wherein the plate is stowed adjacent to the bottom, and an extended configuration, wherein the plate extends from and is perpendicular to a front of the first suitcase. The plate is configured to position an article so that the article is locomoted with the first suitcase.
US11129453B2 Hand-mounted illumination method, system, and devices
A compact precision illumination source mounts on a finger of a user for providing localized illumination for precision tasks such as surgical procedures and other tasks performed in dark or confined spaces. A frame having a circular or arcuate shape engages the finger, and secures an enclosure having a small but powerful bright, light focused on a predetermined region defined by the end of the digit that is likely the activity region for an instrument grasped by the digit.