最新美国发明专利第2021-07-20期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US11066679B2	Closed-ended linear duplex DNA for non-viral gene transfer Aspects of the disclosure relate to a nucleic acid comprising a heterologous nucleic acid insert flanked by interrupted self-complementary sequences, wherein one self-complementary sequence is interrupted by a cross-arm sequence forming two opposing, lengthwise-symmetric stem-loops, and wherein the other of the self-complementary sequences is interrupted by a truncated cross-arm sequence. Methods of delivering the nucleic acid to a cell are also provided.
US11066677B2	Plants with enhanced tolerance to multiple abiotic stresses The present disclosure describes genetically-modified plants having enhanced tolerance to multiple abiotic stressors, such as extreme temperatures (heat or cold) and/or drought. Abiotic stress tolerance is enhanced by ectopic expression of a heterologous glutaredoxin. Abiotic stress tolerance (particularly drought) is also enhanced by inhibited function, activity, or expression of an endogenous glutaredoxin. Methods of producing such genetically-modified plants are also disclosed.
US11066675B2	Increased nucleic-acid guided cell editing in yeast The present disclosure provides methods to increase the percentage of edited yeast cells in a cell population using nucleic-acid guided editing, and automated multi-module instruments for performing these methods.
US11066674B2	Chimeric antigen receptors targeting b-cell maturation antigen The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.
US11066669B2	Oligonucleotides for modulating ATXN2 expression The present invention relates to antisense oligonucleotides that are capable of modulating expression of ATXN2 in a target cell. The oligonucleotides hybridize to ATXN2 mRNA. The present invention further relates to conjugates of the oligonucleotide and pharmaceutical compositions and methods for treatment of neurodegenerative diseases such as spinocerebellar ataxia type 2 (SCA2), amyotrophic lateral sclerosis (ALS), Alzheimer's frontotemporal dementia (FTD), parkinsonism and conditions with TDP-43 proteinopathies using the oligonucleotide.
US11066668B2	Compositions and methods for modulation of IKBKAP splicing The present disclosure provides compounds comprising oligonucleotides complementary to a portion of the IKBKAP gene. Certain such compounds are useful for hybridizing to a portion of the IKBKAP gene, including but not limited to a portion of the IKBKAP gene in a cell. In certain embodiments, such hybridization results in modulation of splicing of the IKBKAP gene. In certain embodiments, the IKBKAP gene includes a mutation that results in defective splicing and a truncated IKAP protein. In certain embodiments, hybridization of oligonucleotides complementary to a portion of the IKBKAP gene results in a decrease in the amount of defective splicing and truncated IKAP protein. In certain embodiments, hybridization of oligonucleotides complementary to a portion of the IKBKAP gene results in an increase in the amount of normal splicing and functional, full-length IKAP protein. In certain embodiments, oligonucleotides are used to treat Familial Dysautonomia.
US11066667B2	Organic compositions to treat APOC3-related diseases The present disclosure relates to compositions and methods for treating APOC3-related diseases such as: hypertriglyceridemia (e.g., Type V Hypertriglyceridemia), abnormal lipid metabolism, abnormal cholesterol metabolism, atherosclerosis, hyperlipidemia, diabetes, including Type 2 diabetes, obesity, cardiovascular disease, and coronary artery disease, among other disorders relating to abnormal metabolism or otherwise, using a therapeutically effective amount of a RNAi agent to APOC3.
US11066666B2	Bioactive renal cells The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.
US11066663B2	Multiplexed deterministic assembly of DNA libraries The present disclosure relates to methods of joining three or more double-stranded (ds) or single-stranded (ss) DNA molecules of interest in vitro or in vivo. The method allows the joining of a large number of DNA fragments, in a deterministic fashion. It can be used to rapidly generate nucleic acid libraries that can be subsequently used in a variety of applications that include, for example, genome editing and pathway assembly. Kits for performing the method are also disclosed.
US11066662B2	Methods for the production of libraries for directed evolution Disclosed herein is an efficient method of generating a library of variants of a sequence of interest, such as may be used in directed evolution, in one embodiment, the method includes an amplification reaction, e.g. error-prone PCR, to generate double-stranded DNA (dsDNA) variants of a sequence of interest, after which one strand of the dsDNA variants may be selectively degraded to produce single-stranded DNA (ssDNA) variants. The ssDNA variants may be hybridized to ssDNA intermediaries, e.g., uracilated circular ssDNA intermediaries, to form heteroduplex DNA, which may be transformed into cells, such as E. coli cells, yielding a library of variants. This method eliminates the inefficient sub-cloning steps and the need for costly primer sets required by many prior methods.
US11066655B2	RNA polymerase, methods of purification and methods of use Cyanophage Syn5 RNA polymerase (RNAP) and methods of purifying it are provided. Cyanophage Syn5 RNAP having one or more promoter mutations are provided. Methods of expressing cyanophage Syn5 RNAP are provided. Novel promoter sequences and in vitro transcription systems utilizing Syn5 RNAP are provided. Methods of making high range ssRNA ladders are also provided. Methods of incorporating 2′-modified dNTPs using Syn5 RNA polymerase are provided.
US11066653B2	Method of transforming bacterial cells The present invention is directed to a producing a DNA methyltransferase in a recombinant host cell, wherein the DNA methyltransferase methylates DNA resulting in a DNA containing 5-methylcytosine within the recognition sequence GCNGC and wherein the DNA methyltransferase comprises less than (35) amino acid residues between amino acid residue (72) and amino acid residue (106) according to the numbering of SEQ ID NO: 33. Furthermore, the present invention is directed to the use of such DNA methyltransferase for the production of bacterial transformants comprising the steps of (a) introducing into a first bacterial host cell a polynucleotide comprising a polynucleotide sequence encoding the DNA methyltransferase to produce a methylated DNA and (b) transferring the methylated DNA from the first bacterial host cell into a second bacterial host cell, wherein the second bacterial host cell comprises a restriction endonuclease able to degrade the DNA but unable to degrade the methylated DNA.
US11066649B2	Method for inducing human cholangiocyte differentiation The invention relates to a method for inducing human cholangiocyte differentiation of progenitor cells called hepatoblasts. More specifically, the invention relates to a method for differentiating hepatoblasts to cholangiocytes by culturing said hepatoblasts with a particular medium having interleukin-6 (IL-6) activity. The differentiation method can specifically induce cholangiocyte differentiation from hepatoblasts, and the human cholangiocytes differentiated according to the invention may be useful for drug discovery for treatment of cholangiopathies and bioengineered livers.
US11066648B2	Compositions and methods for reprogramming adult cells through the stemness of a platelet rich fraction of blood containing platelet-like cells in humans The described invention provides a method of functionally reprogramming adult cells to an immature cell type that expresses one or more embryonic biomarkers with a platelet rich fraction comprising platelet-like cells from umbilical cord blood or peripheral blood, and expanding the immature cell type in vitro under culture conditions to generate an insulin-producing cell population that expresses human beta-cell specific transcription factors and is functionally equivalent to human pancreatic beta-cells. It further provides a pharmaceutical composition comprising a cell product containing a therapeutic amount of an insulin-producing cell population, wherein the insulin-producing cell population expresses human beta-cell specific transcription factors and is functionally equivalent to human pancreatic beta-cells, and a method for treating a recipient subject suffering from a disease characterized by hyperglycemia with the pharmaceutical composition.
US11066647B2	Pluripotent human adipose adult stem cells: isolation, characterization and clinical implications Methods for the efficient isolation and use of pluripotent adipose-derived stem cells (PASCs) are provided. In certain embodiments the methods involve providing an adipose tissue sample from which the stromal vascular fraction is co-cultured with the adipocyte fraction. PASCs can be isolated with a high degree of purification without requiring an additional cell enrichment process (e.g. cell sorting). PASCs and their conditioned media can be used for tissue regeneration within hours of harvesting the adipose tissue, and without requiring cell expansion. PASCs can grow as floating individual cells, as clusters of cells, or attached to surface(s) of the culture vessel. PASCs do not produce teratomas in vivo, nor do they induce immunorejection upon transplantation, and they achieve a high efficiency in grafting. The cells and compositions can be used for cell therapy and to screen new drugs.
US11066646B2	Brown fat cell compositions and methods Methods of developing and using cell lines, such as stem cell lines, for therapeutic or cosmetic use. In one embodiment, the cell lines are used to treat a wide range of degenerative and metabolic disorders including, but not limited to, obesity, diabetes, hypertension, and cardiac deficiency. Also described are methods of using such cell lines to screen for compounds that play a role in regulating a variety of processes.
US11066639B2	Method for the production of a dairy food product and a method for gene transfer by conjugation The present invention relates to the field of microbiology, specifically the field of production of a dairy food product using fermentation and the field of gene transfer by conjugation.
US11066635B2	Method of culturing cells A method of culturing cells including: dividing a culture area into a center area and a plurality of peripheral areas, and designating the center area and the plurality of peripheral areas as measurement positions; calculating: a confluent rate at each of the measurement positions designated; and an average confluent rate which is an average of sum of the confluent rates at the measurement positions designated, the confluent rate being defined as a proportion of an area occupied by cells in a designated area; and determining a timing to perform a subculture of the cells, based on the confluent rate, wherein the determining of the timing further includes determining when the average confluent rate is smaller than a first threshold value, the confluent rate of the center area is larger than a second threshold value, and the second threshold value is larger than the first threshold value.
US11066633B2	Systems and methods for producing micro-engineered models of the human cervix The presently disclosed subject matter provides systems and methods for producing a three-dimensional model of a human cervix. A microdevice is provided for culturing human cervical cells. The microdevice can include an upper microchannel including live ectocervical epithelial cells. The microdevice can include a lower microchannel including a first parallel lane and a second parallel lane including stromal media. The first and the second parallel lanes can be lined with live vascular endothelial cells. The lower microchannel can include a third parallel lane including uterine fibroblasts and live smooth muscle cells embedded in hydrogel. The first, second, and third lanes of the lower microchannel can be separated by protrusion structures. The third parallel lane can be positioned in the lower microchannel in between the first and the second parallel lanes. The microdevice can further include a porous membrane positioned in between the upper microchannel and the lower microchannel.
US11066632B1	Cultivation bag assembly for cultivating microbes A cultivation bag assembly for the cultivation of microbes, fungi and other organisms includes an inner bag for containing a food substrate and an organism to be cultivated. At least one wall of the inner bag is constructed of a layer of water-vapor permeable material. An outer bag of the assembly has first and second walls formed from gas impermeable layers. At least one of the first and second walls of the outer bag has a gas filter patch to allow the passage of oxygen and carbon dioxide gases into and out of the interior of the inner bag to facilitate incubation of the organism within the interior of the inner bag. The inner bag and outer bag are coupled together at a first end of each of the inner bag and outer bag.
US11066631B2	Pack A pack includes at least one stack with Petri dishes which extends in a longitudinal direction, a connecting device which holds the at least one stack together, and an outer packaging which surrounds the at least one stack and which can be opened to remove the at least one stack.
US11066630B2	Device and method for analysis of tissue constructs The present invention provides an integrated microphysiological device and fabrication methods thereof, as well as methods of use to perform biological assays.
US11066629B2	Lipid metabolism-promoting composition including isoxanthohumol The present invention aims to provide a composition for promoting lipid metabolism, a composition for suppressing fat accumulation, and the like, which contain, as an active ingredient, a substance that is thermally stable and adequately water-soluble and that has lipid metabolism-promoting action. The present invention relates to a composition for promoting lipid metabolism containing isoxanthohumol.
US11066618B2	Organic lubricant An organic lubricant composition comprising a vegetable oil; an organic acid; and an organic alcohol, where the organic lubricant composition is substantially free of inorganic compounds.
US11066617B2	Quaternary ammonium compounds as fuel or lubricant additives A quaternary ammonium compound of formula (X): wherein R0, R1, R2 and R3 is each individually an optionally substituted alkyl, alkenyl or aryl group and R includes an optionally substituted hydrocarbyl moiety having at least 5 carbon atoms.
US11066610B2	Systems and processes for suppressing heavy polynuclear aromatic deposition in a hydrocracking process The disclosure describes refinery processes and process units for suppressing the precipitation and deposition of heavy polynuclear aromatic (HPNA) compounds in a process unit of a refinery, by combining the effluent from a hydrocracking unit with an aromatic solvent stream. Certain costly HPNA treatment processes can be eliminated, downtime can be reduced, and overall distillate yield can be increased by suppressing HPNA precipitation. The aromatic bottoms—which are suitable solvents for this purpose—of an aromatic recovery complex can be used in certain embodiments to dissolve HPNAs and suppress HPNA precipitation.
US11066607B1	Process for producing deasphalted and demetallized oil A process and system for producing deasphalting and demetallized oil from an initial feed such as a heavy feed is provided. The feed is contacted with an effective quantity of solvent to promote phase separation, to produce an asphalt phase and a reduced asphalt content phase. The reduced asphalt content phase is contacted with an effective amount of solid adsorbent to remove undesirable metal compounds to produce an oil phase substantially-free of asphalt and substantially-free of metal. The oil phase that is substantially-free of asphalt and substantially-free of metal is subjected to flash separation to produce a solvent fraction for recycle and an oil phase effluent substantially-free of asphalt and substantially-free of metal for recovery as the desired product.
US11066606B2	Systems and methods for catalytic upgrading of vacuum residue to distillate fractions and olefins with steam Systems and methods for upgrading a heavy oil feed to a light product comprising distillate fractions and olefins, the method including combining a heavy oil feed with a naphtha-based cracking additive to produce a mixed heavy oil feed; heating the mixed heavy oil feed with a nano-zeolite catalyst in the presence of steam to effect catalytic upgrading of the mixed heavy oil feed to produce lighter distillate fractions and olefins in an upgraded product, the upgraded product including at least about 30 wt. % olefins; and separating the lighter distillate fractions from the olefins.
US11066602B2	Reactive mesogen and liquid crystal composition including the same Provided are a reactive mesogen that may improve display quality of a liquid crystal display, and a liquid crystal composition including the same. The reactive mesogen is represented by the following Formula: BZ1b1XZ2b2Pa where X, Z1, Z2, B, and Pa are specified in the disclosure, and each of b1 and b2 is independently an integer between 0 to 6, inclusive.
US11066593B2	Microemulsion flowback aids for oilfield uses Flowback aid mixtures and oil-in-water microemulsions produced by combining an aqueous brine with the flowback aid mixtures are disclosed. The flowback aid mixture comprises an oil, a fatty alcohol ethoxylate, and a quaternized fatty amine ethoxylate. The amount of oil is less than or equal to 12 wt. % based on the amount of flowback aid mixture. The microemulsions have a surface tension at 25° C. less than 30 mN/m and a Z-average particle size as determined by dynamic light scattering at 25° C. of less than or equal to 10 nm. Also disclosed are processes that utilize the flowback aid mixtures. In one process, the mixture is introduced into a subterranean formation and is combined prior to or during its introduction into the formation with a formation brine, process water, or both to give the microemulsion. In one hydraulic fracturing process for recovering gas, oil, or both, a fracturing fluid and the flowback aid are co-injected into a subterranean formation to give the microemulsion.
US11066589B2	Use of biodegradable hydrocarbon fluids as drilling fluids The invention is a fluid having a kinematic viscosity from 3 to 6 mm2/s, a flash point of higher than 120° C. and a pour point lower than −40° C., having a boiling point in the range of from 200° C. to 400° C. and a boiling range below 80° C., said fluid comprising more than 95% isoparaffins and less than 3% of naphthens by weight, a biocarbon content of at least 95% by weight, containing less than 100 ppm aromatics by weight. The invention is also a drilling fluid and the use of the fluid to improve the viscosity of the drilling fluid.
US11066586B2	Curable composition, adhesive sheet, cured product, laminate, method for producing adhesive sheet, and device Provided is a curable composition that can, when cured, form a cured product having adhesiveness and adhesion to an adherend at excellent levels. The curable composition contains a polyorganosilsesquioxane and one of (A) a compound represented by Formula (X); and (B) a polymerization stabilizer, where Formula (X) is expressed as follows: wherein r1 represents an integer from 4 to 20; L represents a group containing epoxy, oxetanyl or vinyl ether group; R11 and R12 each represent an optionally substituted hydrocarbon group; s1 represents an integer from 1 to 3; t1 represents an integer from 0 to 2, where s1 plus t1 equals 3; and R13 and R14 are selected from hydrogen and an optionally substituted hydrocarbon group. The polyorganosilsesquioxane has a number-average molecular weight of 1000 to 3000 and a molecular-weight dispersity of 1.0 to 3.0, includes a constitutional unit represented by Formula (1), has a ratio of a constitutional unit represented by Formula (I) to a constitutional unit represented by Formula (II) of 5 or more, and has a total proportion of the constitutional unit represented by Formula (1) and a constitutional unit represented by Formula (4) of 55 to 100 mole percent of all siloxane constitutional units. [R1SiO3/2] (1), [RaSiO3/2] (I), [RbSiO2/2(ORc)] (II), [R1SiO2/2(ORc)] (4), where R1 represents an epoxy-containing group; Ra and Rb are each selected from an epoxy-containing group, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, and hydrogen; and Rc is selected from hydrogen and C1-C4 alkyl.
US11066585B2	Organopolysiloxane composition and method for producing same, and silicone composition for mist suppressor as well as solvent-free release paper or release film An organopolysiloxane composition obtained by dissolving in a solvent an organopolysiloxane crosslinked product obtained by repeating one or more times a process of again introducing an organopolysiloxane and an organohydrogenpolysiloxane to a product, obtained by conducting an addition reaction of an organopolysiloxane of a specific structure and an organohydrogenpolysiloxane of a specific structure using a platinum group metal-based compound in 10-50 times the total mass of these polysiloxanes, and conducting an addition reaction using a platinum group metal-based compound.
US11066579B2	Curable composition and method for reinforcing shaped structure with use of same This curable composition can easily reinforce shaped objects and the reinforced shaped objects have good color developability and excellent texture. The curable composition includes a 2-cyanoacrylic acid ester and a surface conditioner, in which the c content of the surface conditioner is 0.001-10 parts by mass relative to 100 parts by mass of the 2-cyanoacrylic acid ester, and the surface tension of the composition is 28 mN/m or less at 25° C. Preferred surface conditioners are silicone-based and fluorinated surface conditioners. Reinforced shaped objects and a method for reinforcing shaped objects using the curable composition are also provided.
US11066578B2	Pressure sensitive adhesive compositions A pressure sensitive adhesive having improved flame retardancy properties, methods for making same and applications thereof are described. The pressure sensitive adhesive comprises an aqueous based acrylic emulsion and a mixture of halogenated and non-halogenated flame retardants.
US11066574B2	Self-healing coating compositions The present disclosure provides a self-healing coating composition precursor that includes a soft segment precursor, a hard segment precursor, and a diol. The present disclosure also provides self-healing coatings including the same for scratches and deep cracks and/or anti-fouling property, and methods of preparation and use thereof.
US11066566B2	Inkjet printing systems The present disclosure is drawn to an inkjet printing system including an ink composition and a microfluidic ejection assembly. The ink composition can include carbon black pigment, from 50 wt % to 80 wt % water, from 10 wt % to 40 wt % of an organic solvent system, and from 0.5 wt % to 6 wt % polyurethane. The microfluidic ejection assembly can include a drop generator for externally ejecting the ink composition, and a fluid pump for internally inducing microfluidic recirculation flow of the ink composition into the drop generator.
US11066563B2	Radiation curable ink A radiation curable ink comprises a compound represented by the following Formula (I): a compound represented by the following Formula (II): and a compound represented by the following Formula (III):
US11066558B2	Asphalt composition, method for producing same and additive for asphalt The present invention relates to an asphalt composition enabling one to provide an asphalt pavement in which the occurrence of rutting and fatigue cracking is inhibited and a method for producing the same, and to an additive for asphalt. The asphalt composition contains asphalt and cellulose, wherein the content of the cellulose is 0.01 part by mass or more and 10 parts by mass or less based on 100 parts by mass of the asphalt, and a crystallization index of the cellulose is 50% or less.
US11066557B2	Protein-surfactant-monomer/polymer blends and copolymers for protein-based plastics Disclosed are copolymers comprising a modified protein first monomer, a surfactant, and a second monomer. Methods of making copolymers comprising a modified protein first monomer, a surfactant, and a second monomer are described. Also disclosed are articles comprising the copolymers. Disclosed are blends comprising a protein, a surfactant, and a second monomer. Methods of making blends comprising a protein, a surfactant, and a second monomer are described. Also disclosed are articles comprising the blends.
US11066549B2	(Meth)acrylate functionalized poly(meth)acrylate-block-polyimide- block-poly(meth)acrylate copolymer, preparation method and use thereof This invention relates to a (meth)acrylate-functionalized poly(meth)acrylate-block-polyimide-block-poly(meth)acrylate copolymer, preparation method and use thereof. The (meth)acrylate-functionalized poly(meth)acrylate-block-polyimide-block-poly(meth)acrylate copolymer according to the present invention exhibits outstanding thermal stability and excellent optical properties.
US11066539B2	Rubber composition The present invention relates to [1] a rubber composition exhibiting excellent grip force, which contains (A) a rubber component, (B) a lignin degradation product having an aldehyde yield, according to an alkaline nitrobenzene oxidation method, of 12% by mass or more, and (C) an anti-aging agent; [2] a shoe sole using the rubber composition of the above [1]; and [3] a grip force improving agent for rubber compositions, containing (B) a lignin degradation product having an aldehyde yield, according to an alkaline nitrobenzene oxidation method, of 12% by mass or more, as an active ingredient.
US11066535B2	Bio-based binders including carbohydrates and a pre-reacted product of an alcohol or polyol and a monomeric or polymeric polycarboxylic acid An environmentally friendly, formaldehyde-free, aqueous binder composition that includes a carbohydrate, a crosslinking agent, and a pre-reacted product of an alcohol or polyol and monomeric or polymeric polycarboxylic acid or polyglycerol is provided. The pre-reacted product may include glycerol and esters of citric acid such a monoglyceryl citrate, diglyceryl citrate, and triglyceryl citrate as well as other higher molecular weight citric acid-based esters. The inclusion of the pre-reacted product in the binder composition helps to speed the crosslinking reaction, induces faster water evaporation, decreases the viscosity of the binder, helps to reduce the amount of water needed for application of the binder, decreases tackiness, and helps to achieve a maximum vertical expansion of the insulation pack in the transfer zone. The binder composition may be used in the formation of insulation materials and non-woven chopped strand mats.
US11066534B2	Polyether-modified silicone composition, surfactant, foam stabilizer, polyurethane foam forming composition, and cosmetic preparation including said composition, and method for producing said composition Provided is a polyether-modified silicone composition. The composition comprises (A) a polyether-modified silicone, and (B) a monool organic compound. The monool organic compound (B) is selected from (B1) a glycol ether compound having a hydrogen atom substituted by an alkyl group having from 2 to 8 carbon atoms at one end, a secondary alcoholic hydroxy group at the other end, from 2 to 3 repeating oxyalkylene units having from 2 to 4 carbon atoms, and (B2) a tripropylene glycol monomethyl ether. Isopropyl alcohol does not exceed 1 mass % of the entire composition. Applications and manufacturing methods for the composition are also provided.
US11066529B2	Water-soluble matrix, pre-molded article containing resin particles, and method for producing resin particles Provided are: a water-soluble matrix whose melt-kneading temperature can be adjusted according to the melting point or glass transition temperature of a resin; a pre-molded article in which resin particles are dispersed in the water-soluble matrix; and a method for producing resin particles. This production method includes melt-kneading a water-soluble matrix containing a modified polyvinyl alcohol-based resin and a water-soluble saccharide at a weight ratio of the former/the latter=from 99/1 to 50/50 and a thermoplastic resin, and bringing the pre-molded article in which the resin particles are dispersed into contact with an aqueous solvent to elute the matrix. The modified polyvinyl alcohol-based resin contains in a side chain thereof an alkyl group including at least one hydroxyl group (for example, a 1,2-dihydroxyalkyl group).
US11066523B2	Photochromic polyrotaxane compound and curable composition comprising the photochromic polyrotaxane compound A photochromic polyrotaxane compound which comprises an axial molecule and a plurality of cyclic molecules clathrating the axial molecule, wherein at least one side chain containing a photochromic moiety is bonded to at least one of the cyclic molecules, and a curable composition comprising the photochromic polyrotaxane compound and a polymerizable compound.
US11066519B2	Photoresponsive hexahydrotriazine polymers This disclosure describes new compositions and methods related to photoresponsive poly(hexahydrotriazines) and related polymers. In an embodiment, a method of patterning a substrate includes forming a liquid poly(hemiaminal) material by a process that includes forming a reaction mixture comprising a polar solvent, paraformaldehyde, and an aminobenzene compound having photoreactive groups, and heating the reaction mixture at a temperature up to 50° C. The method further includes applying the liquid poly(hemiaminal) material to a substrate; patterning the liquid poly(hemiaminal) material with UV light; and curing the liquid poly(hemiaminal) material to form a cured poly(hexahydrotriazine) polymer.
US11066514B2	Soil release polymer composition comprising an anionic modified polyester A polymer composition that includes a polyester terephthalate. A method of making a liquid laundry detergent composition using the polymer composition.
US11066512B2	Method of preparing oligomeric polyol compositions There is provided an oligomeric polyol composition having (a) an oligomeric network containing residues of at least one polyhydroxylated aromatic compound and residues of at least one polyol having at least three hydroxyl groups; and (b) a plurality of peripheral groups having one or more pendant hydroxyl groups bound to the oligomeric network by a plurality of linking units. The residues of the polyol may optionally contain one or more oxygen ether groups, one or more amino ether groups, or both of one or more oxygen ether groups and one or more amino ether groups. Reaction of the oligomeric polyols with isocyanate monomers affords a new class of polyurethanes having superior heat and water resistance. The new polyurethanes exhibit lower peak exotherms, typically less than 250° F. during in-mold polymerization. Articles prepared from polyurethanes incorporating such oligomeric polyol compositions exhibit flexural strengths and moduli in excess of 10,000 psi and 400,000 psi respectively, and outstanding green strength.
US11066510B2	Epoxy resin composition, process for producing same, and uses of said composition The present invention provides an epoxy resin composition that can produce a cured product maintaining good dielectric characteristics (low dielectric constant and low dielectric loss tangent), and having high adhesion strength to metal; and also provides a process for producing the same, a cured product obtained by curing the epoxy resin composition, and use thereof. The present invention includes an epoxy resin composition comprising an epoxy resin, an acid anhydride-based curing agent, and a curing accelerator, the epoxy resin being represented by the formula (1): wherein X is a divalent group obtained by removing two hydrogen atoms from a hydrocarbon ring, or a divalent group represented by the formula (2): wherein Y is a bond, a C1-6 alkylene group, etc.; R1 is the same or different, and is a C1-18 alkyl group, etc.,R2 is the same or different, and is a C1-18 alkylene group, etc.,R3 is the same or different, and is a C1-18 alkyl group, etc., andn is the same or different, and is an integer of 0 to 3. The present invention also includes a process for producing the same, a cured product of the epoxy resin composition, and use thereof.
US11066509B2	Conductive paste composition, device comprising electrode formed from same, and method for producing conductive paste composition A conductive paste composition includes 1 to 10 parts by weight of a binder (A), 2 to 20 parts by weight of an epoxy monomer (B), 1 to 20 parts by weight of a crosslinking agent (C), and 70 to 95 parts by weight of a conductive filler (D). The binder (A) is a reactive oligomer having a siloxane bond as a main skeleton and including a plurality of oxirane rings as an organic group. The epoxy monomer (B) includes an oxirane ring. The total amount of the binder (A), the epoxy monomer (B), the crosslinking agent (C), and the conductive filler (D) is 100 parts by weight.
US11066507B2	Solid cyanoacrylate compositions A cyanoacrylate composition with thermoplastic polyurethane, formulated as a non-flowable soft solid or semi solid mass, for example in stick form, is reported.
US11066506B2	Polymer composition and coatings prepared from the same The present disclosure relates to a composition comprising: at least one dendritic polymer prepared from hyper-branched polymer with hydroxyl groups, having a plurality of peripheral functional groups, wherein the peripheral functional groups comprising at least one cyclic ether group that is covalently bound to said hyperbranched polymer by urethane linkages; and a melamine-based crosslinker. Such compositions have improved flexibility. The present disclosure further relates to the use of such compositions to form coatings after cure, or as an additive component to binder resins.
US11066503B2	Very soft, non-sticky and transparent styrenic thermoplastic elastomer composition Thermoplastic elastomer compositions can be used for medical skin contact applications, comprising: a) 90.9 to 69.0 wt.-% star-shaped block copolymer A with 4 arms of the general structure [S1—(S/B)k—(S/B)I—(S/B)m—S2]n—X, where S1 and S2 are vinylaro-matic hard polymer and S/B are soft random vinylaromatic/diene copolymer blocks; X is a coupling center; and b) 9.1 to 31.0 wt.-% of a plasticizer B: b1) a mixture of mineral oil B1 and cyclohexane 1,2-dicarboxylic acid C8 to C10 dialkyl ester B2; or b2) a mixture of mineral oil B1 and vegetable oil B3.
US11066499B2	Medium density polyethylene compositions An ethylene alpha-olefin copolymer having (a) a density of from about 0.910 g/cc to about 0.940 g/cc; (b) a weight average molecular weight of from about 150,000 g/mol to about 300,000 g/mol; and (c) a melt index at a load of 2.16 kg of from about 0.01 dg/10 min. to about 0.5 dg/min.; wherein a 1 mil blown film formed from the polymer composition is characterized by (i) a Dart Impact strength greater than about 175 g/mil; (ii) an Elmendorf machine direction tear strength greater than about 20 g/mil; and (iii) an Elmendorf transverse direction tear strength greater than about 475 g/mil.
US11066496B2	Super absorbent polymer and method for preparing same The present invention relates to a super absorbent polymer and a method for preparing the same. According to the method for preparing a super absorbent polymer of the present invention, the super absorbent polymer +having improved absorption capacity and permeability can be prepared.
US11066494B2	Amine bridged anilide phenolate catalyst compounds The present disclosure provides catalyst compounds having an amine bridged anilide phenolate ligand. In at least one embodiment, catalysts of the present disclosure provide catalyst activity values of about 90 gP/mmolCat·h−1 or greater and polyolefins, such as polyethylene copolymers, having comonomer content of from about 4 wt % to about 12 wt %, an Mn of about 90,000 g/mol or more, an Mw of 155,000 g/mol or more, and an Mw/Mn of from 1 to 2.5.
US11066491B2	Cationic polymers and porous materials According to one or more embodiments, cationic polymers may be produced which include one or more monomers containing cations. Such cationic polymers may be utilized as structure directing agents to for mesoporous zeolites. The mesoporous zeolites may include micropores as well as mesopores, and may have a surface area of greater than 350 m2/g and a pore volume of greater than 0.3 cm3/g. Also described are core/shell zeolites, where at least the shell portion includes a mesoporous zeolite material.
US11066489B2	Bis-phenyl-phenoxy polyolefin catalysts having two methylenetrialkylsilicon ligands on the metal for improved solubility Embodiments are directed to a catalyst system comprising metal ligand complexes and processes for polyolefin polymerization using the metal ligand complex having the following structure: where each X is selected from the group consisting of —(CH2)SiRX3.
US11066485B2	Modified starch Described herein is an octenyl succinic acid modified starch (OSA modified starch) degraded by at least one enzyme capable of cleaving 1,4-linkages of a starch molecule from the non-reducing ends to produce short chain saccharides, wherein the content of non-covalently bound, free octenyl succinic acid in the OSA modified starch is less than about 0.50% by weight, based on total weight of the modified starch, and wherein content of alpha-1,6-glycosidic linkages is higher than 12%, a method of preparing same, and an encapsulation agent comprising same as well as a method of encapsulating an active agent with said encapsulation agent.
US11066484B2	Cellulose acetate and method for producing cellulose acetate Provided is cellulose acetate with which a hollow fiber membrane having excellent salt rejection and water permeability can be produced. The cellulose acetate, in which a total content of calcium and magnesium is 2.8 to 3.5 μmol/g; a 6 percent viscosity is 40 to 80 mPa·s; a degree of filtration Kw is 35 g−1 or less; a molecular weight distribution Mw/Mn is 3.00 or less; and a degree of acetylation is 61.3 to 62.3%.
US11066481B2	Antibodies to coagulation factor XIa and uses thereof In one aspect, antibodies, or antigen-binding fragments thereof, that specifically bind to activated Factor XI (FXIa) are provided. Also provided are methods of obtaining such antibodies and nucleic acids encoding the same. In another aspect, compositions and therapeutic prevention of thrombotic diseases, disorders or conditions are provided. In another aspect, anti-idiotype antibodies that bind anti-FXIa antibodies of the disclosure, as well as compositions comprising the anti-idiotype antibodies, methods of obtaining the antibodies and nucleic acids encoding the same, are also provided.
US11066479B2	Monoclonal antibodies targeting glypican-2 (GPC2) and use thereof A panel of human variable heavy (VH) single domain monoclonal antibodies specific for cell-surface glypican-2 (GPC2) are described. Methods for the diagnosis and treatment and GPC2-positive cancer are also described. Recombinant immunotoxins comprised of a GPC2-specific VH domain antibody and a clinically used form of Pseudomonas exotoxin A (PE38) were generated and shown to inhibit GPC2-positive neuroblastoma tumor cell growth and inhibit neuroblastoma xenograft growth in nude mice, without significant toxicity. Chimeric antigen receptors comprising a GPC2-specific VH single domain antibody are also described. T cells expressing the GPC2-specific CARs potently killed GPC2-positive neuroblastoma cells in a dose-dependent manner.
US11066477B2	Monoclonal antibody against MELK and utilization thereof The present invention relates to monoclonal antibodies against MELK. Furthermore, the present invention provides methods for diagnosing MELK-associated diseases using the antibodies, methods for detecting the MELK protein, methods for determining the drug efficacy following treatment with a MELK inhibitor, methods of screening for subjects to whom a MELK inhibitor has a high therapeutic effect, and diagnostic reagents containing the antibodies.
US11066474B2	Anti-TrkB monoclonal antibodies and methods of use The present invention provides antibodies that bind specifically to TrkB and methods of using the same. According to certain embodiments, the antibodies of the invention are agonist antibodies that are neuroprotective, as shown by their effect on enhancing the survival of retinal ganglion cells in vitro. As such, these agonist antibodies may be used to treat diseases or disorders of the eye, such as, but not limited to glaucoma. In addition, other neuronal diseases or disorders may benefit from treatment with these agonist antibodies, including any disease or disorder characterized in part by neuronal damage. In certain embodiments, the invention includes antibodies that bind TrkB and mediate cell signaling. The antibodies of the invention may be fully human, non-naturally occurring antibodies.
US11066470B2	Humanized antibodies with increased stability The present invention provides antibodies having improved stability. Included are antibodies that are capable of binding to KIR3DL2 polypeptides. The antibodies are suitable for the treatment of disorders characterized by KIR3DL2-expressing cells, particularly CD4+ T cells, including malignancies such as Mycosis Fungoides and Sezary Syndrome, and KIR3DL2-expressing autoimmune disorders.
US11066466B2	Inhibition of SCUBE2, a novel VEGFR2 co-receptor, suppresses tumor angiogenesis An isolated anti-SCL)BE2 (Signal peptide-complement protein Clr/CIs, Uegf: and Bmp 1 (CUB)-epidermal growth factor (EGF) domain-containing protein 2) antibody or a binding fragment thereof is disclosed. The anti-SCUBE2 antibody comprises an antigen binding region that specifically hinds to a target domain located within SCUBE2 (SEQ ID NO: 66) and exhibits a property of inhibiting vascular endothelial growth factor (VEGF)-induced angiogenesis. The target domain is selected from the group consisting of the EGF-like motifs 4 to 6 ranging from a.a. position 175 to 323, or the spacer region ranging from a.a. position 441 to 659, or the first cys-rich motif ranging from a.a. position 668 to 725 of SCUBE2 (SEQ ID NO: 66). The anti-SCUBE2 antibody or binding fragment thereof is for use in treating a disease associated with VEGF-induced angiogenesis, or in treating a tumor or inhibiting tumor angiogenesis and cancer cell growth in a subject in need thereof.
US11066464B2	Anti-malarial antibodies that bind circumsporozoite protein Antibodies that bind to the circumsporozoite protein (CSP) of Plasmodium falciparum. Use of such antibodies as anti-malarial agents, to confer protection against infection by malarial parasites such as P. falciparum by insect vector transmission. Diagnosis of malaria using anti-CSP antibodies. Methods of determining efficacy of candidate vaccine compositions in development and testing of anti-malarial vaccines.
US11066463B2	Anti-polyubiquitin antibodies and methods of use The invention provides anti-polyubiquitin antibodies and methods of using the same.
US11066456B2	Compositions comprising TREM2 and methods of use thereof The present invention provides TREM2 constructs. TREM2 constructs of the invention are polynucleotide sequences encoding a polypeptide, wherein the polypeptide comprises at least one TREM2 or fragment thereof and a targeting moiety and optionally comprising a signal peptide and/or a purification moiety. The present invention also provides isolated polypeptides encoded by TREM2 constructs, vectors comprising TREM2 constructs, isolated cells comprising said vectors, and methods of use thereof.
US11066454B2	Compositions comprising variants and fusions of FGF19 polypeptides The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21), and variants or fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
US11066449B2	Microbial nanowires with increased conductivity and reduced diameters Improved electrically conductive pili were generated from a natural pilus protein from the microorganism Geobacter sulfurreducens. Substituting a tryptophan for the phenylalanine at position F51 and a tryptophan for the tyrosine at position Y57 of the pilus monomer substantially increased the conductivity of the pili and reduced their diameter to 1.5 nm. Substantial improvements in conductivity were also achieved by substituting an additional tyrosine, histidine, and phenylalanine in the pilus monomer to mimic the monomer of Geobacter metallireducens, but the pili retained the typical Geobacter sulfurreducens wild-type diameter of 3 nm.
US11066448B2	Zika as a cell penetrating peptide for delivery to the brain In various embodiments constructs are provided for the delivery of an effector molecule into a cell. In certain embodiments the construct comprises a cell penetrating peptide (CPP) attached to an effector that is to be delivered into a cell, where the cell penetrating peptide comprises a Zika cell penetrating peptide (Zika CPP), and the effector is selected from the group consisting of a protein, a nucleic acid, an organic compound, a nanoparticle, a viral particle, and the like.
US11066444B2	BMP-2-binding peptide amphiphile nanofibers Provided herein are peptide amphiphiles with binding affinity for the bone promoting growth factor BMP-2, and methods of use thereof. In particular nanofibers and gel scaffolds of BMP-2-binding peptide amphiphiles are provided.
US11066441B2	Method for separating and purifying α2-macroglobulin from Cohn Fraction IV precipitation The present invention discloses a method for separating and purifying α2-macroglobulin from Cohn Fraction IV precipitation, in which Cohn Fraction IV precipitation is treated by ammonium sulfate precipitation, zinc ion affinity chromatography, gel filtration, and ultrafiltration and concentration sequentially and thereby α2-macroglobulin is obtained finally. With the method provided in the present invention, purified α2-macroglobulin plasma protein that has a clinical application value is obtained, the Cohn Fraction IV precipitation is changed from a discarded material into a valuable material, and plasma is utilized comprehensively. In addition, the method is easy and simple to use, easy to scale up, and suitable for separation and purification of α2-macroglobulin at a large scale.
US11066439B2	Synthesis of liraglutide The present invention relates to the efficient solid-phase synthesis of liraglutide represented by Formula-I. The present invention relates to an efficient process for the preparation of liraglutide by sequential coupling employing solid phase approach. It involves sequential coupling of protected amino acids to prepare backbone of liraglutide and upon completion of linear sequence, synthesis was extended from lysine side chain by adding γ-glutamic acid and palmitic acid, followed by removal of protective groups, cleavage of the peptide from solid support and purification of crude liraglutide obtained. The present invention also involves the usage of inorganic salts during the coupling, wash with HOBt in DMF solution after Fmoc-deprotection step to suppress the aggregation of peptides and ensure reactions are going for completion, and thus avoid deletion sequences and improve the process yield.
US11066438B2	Squalamine solid forms and methods of making the same Provided herein are crystalline solid forms of squalamine phosphate designated as Form 1 and Form 2, compositions containing one or both forms, and methods of their preparation and of their use.
US11066431B2	Complex and method for producing same A complex has a structure of formula (1A): SnXn·(m)L, wherein X is at least one type of halogen atoms, L is a polar solvent molecule, n is a value from 1.5 to 2.5, and m is a value from 0.3 to 1.9. A perovskite compound has a structure of formula (2A): RSnXj, wherein Sn has an oxidation number from 1.5 to 2.5, R is at least one type of a monovalent cation, X is at least one type of halogen atoms, and j is a value from 2.5 to 3.5, and the perovskite compound is free of tin oxide; or a perovskite compound has a structure of formula (2B): R2M2BiX1, wherein R is at least one type of a monovalent cation, X is at least one type of halogen atoms; M2 is a monovalent metal, and i is a value from 5.0 to 7.0.
US11066429B2	Process for producing acetoxy-bearing siloxanes Described is a process for producing preferably trifluoromethanesulfonic acid-acidified, end-equilibrated, acetoxy-bearing siloxanes which comprises reacting cyclic siloxanes, in particular comprising D4 and/or D5, and/or cyclic branched siloxanes of the D/T type with acetic anhydride using preferably trifluoromethanesulfonic acid as catalyst and with addition of acetic acid, wherein the cyclic branched siloxanes of the D/T type are mixtures of cyclic branched siloxanes of the D/T type which may contain not only siloxanes comprising D and T units but also siloxanes comprising Q units.
US11066428B2	Bis-phenyl-phenoxy polyolefin catalysts having a methylenetrialkylsilicon ligand on the metal for improved solubility Embodiments are directed to a catalyst system comprising metal-ligand complexes and processes for polyolefin polymerization using the metal-ligand complex having the following structure, Formula (I), where X is selected from the group consisting of —(CH2)SiRX3.
US11066427B2	Organosilane compounds having bulky substituent and preparation thereof The invention provides an organosilane compound having a more bulky substituent group than the existing organosilane compounds. The compound is represented by formula (1) wherein R1 is a C4-C10 tertiary hydrocarbon group, R2 is a C1-C10 alkyl group, and LG is halogen or trifluoromethanesulfonyloxy.
US11066423B2	Monomeric bimetal hydroxycitric acid compounds and methods of making and using the same Monomeric bimetal hydroxycitric acid (HCA) compounds are provided. The subject compounds include a divalent metal (X) bonded to the carboxylic acids of C2 and C3 and a monovalent metal (Y) bonded to the carboxylic acid of C1. Also provided are methods of preparing the subject compounds from a dimeric starting material (e.g., X3(HCA)2) which include acidifying the dimer to produce a monomeric intermediate which is subsequently neutralized with YOH base. Methods of alleviating at least one symptom associated with a target disease or condition in a subject are provided. Also provided are compositions including the subject monomeric bimetal HCA compounds which find use in a variety of therapeutic applications.
US11066420B2	Inhibitors of low molecular weight protein tyrosine phosphatase (LMPTP) and uses thereof Protein tyrosine phosphatases (PTPs) are key regulators of metabolism and insulin signaling. As a negative regulator of insulin signaling, the low molecular weight protein tyrosine phosphatase (LMPTP) is a target for insulin resistance and related conditions. Described herein are compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and compositions, and methods of using these compounds and compositions.
US11066417B2	Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulators Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
US11066415B2	Compositions and methods for regulating glucose homeostasis and insulin action The present invention encompasses the use of compounds for a novel approach to treat and prevent diseases, conditions, and disorders such as diabetes and ischemic reperfusion injury. Compounds of the invention, including but not limited to BAM15 ((2-fluorophenyl){6-[(2-fluorophenyl)amino](1,2,5-oxadiazolo[3,4-e]pyrazin-5-yl)}amine), a mitochondrial uncoupler, can improve glucose tolerance, increases cellular oxygen consumption, treat or prevent kidney ischemia reperfusion injury reverse insulin resistance, reverse or treat hyperinsulinemia, and reverse or treat hyperlipidemia. The present invention further provides novel compounds as well as methods for identifying compounds with the same or similar properties as BAM15.
US11066413B2	Aminopyrimidine five-membered heterocyclic compound, and intermediate, preparation method, pharmaceutical composition and application thereof Disclosed in the present invention is an aminopyrimidine five-membered heterocyclic compound, and an intermediate, preparation method, pharmaceutical composition and application thereof. The aminopyrimidine five-membered heterocyclic compound provided by the present invention has a significant antagonistic effect on adenosine A2A receptors, and may be used as an antagonist for adenosine A2A receptors to effectively relieve or treat immune tolerance, diseases of the central nervous system, inflammatory diseases and like related diseases, while the preparation method is simple.
US11066410B2	Fused triazolo-pyrimidine compounds having useful pharmaceutical application A compound and/or a pharmaceutically acceptable salt thereof has the following formula A: These compounds can be PIKfyve kinase inhibitors.
US11066407B2	Preparation of certain substituted 1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof The present invention provides methods for the preparation of certain optionally substituted heterocycle fused gamma-carbolines of Formula 2F, as shown below and as further defined herein:
US11066406B2	Small molecule inhibitors of the JAK family of kinases 2-((1r,4r)-4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)cyclohexyl)acetonitrile compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions mediated by JAK.
US11066398B2	Small molecule c-Myc inhibitors This invention provides small molecule Myc-inhibitors. Also provided in the invention are therapeutic applications of these compounds for treating Myc-driven cancer and other related methods.
US11066397B2	Proteasome inhibitors and uses thereof The compounds of the present invention are represented by the following compounds having Formula (I) where the substituents R, R1-R5, k, m, n, and q are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders, infectious disease, or for providing immunosuppression for transplanted organs or tissues.
US11066395B2	Dimethylaminoethanol salt of a GLP-1 receptor modulator Crystalline 2-hydroxy-N,N-dimethylethanaminium 1-(2-(5-(tert-butyl)-thiophene-2-carboxamido)-3-(4-(5-(4′-ethyl-[1,1′-bi(cyclohexan)]-3-en-4-yl)pyrimidin-2-yl)phenyl)propanoyl)azetidine-3-carboxylate salt, and methods related to synthesis and therapeutic use of the same.
US11066394B2	Solid forms of an HPK1 inhibitor The present invention relates to salt forms of the hematopoietic progenitor kinase 1 (HPK 1) inhibitors N-(2-((2S,4S)-4-Amino-2-(hydroxymethyl)pyrrolidin-1-yl)-5-fluorophenyl)-2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxamide and N-(2-((2S,4S)-4-Amino-2-(hydroxymethyl)pyrrolidin-1-yl)-4-(4-cyanopyridin-3-yl)phenyl)-2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxamide, including methods of preparation thereof, where the compounds are useful in the treatment of HPK1 mediated diseases such as cancer.
US11066392B2	Inhibitors of indoleamine 2,3-dioxygenase and methods of their use There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
US11066391B1	Atorvastatin derived HMG-CoA reductase degradation inducing compound The present invention relates to bifunctional compounds that induce HMG-CoA reductase degradation, in which in which atorvastatin and E3 ubiquitin ligase binding moiety are chemically linked. The present invention also relates to a preparation method of the compounds, a method for degrading HMG-CoA reductase using the compounds, and a composition for the prevention or treatment of HMG-CoA reductase-related diseases comprising the compounds.
US11066389B2	Process for the manufacturing of medicaments The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid
US11066386B2	CGRP receptor antagonists The present invention provides compounds of Formula II or a pharmaceutically acceptable salts thereof, useful as a CGRP receptor antagonist.
US11066379B2	Gracilin A and congeners as immunosuppressive and neuroprotective agents Gracilin A congeners and methods for their use as immunosuppressive and neuroprotective agents.
US11066378B2	Caffeic acid derivatives for anti-angiogenesis The present invention develops a series of methyl caffeate derivatives having biological activity in anti-angiogenesis. The present invention suggests that the compounds of the invention possess inhibiting angiogenesis through regulation of VEGF/VEGFR-2 and its downstream signaling cascades in the vascular endothelial cells (VECs).
US11066377B2	Process for producing aromatic primary diamines The present disclosure relates to a process for the production of aromatic primary amines, by reacting an aromatic dialdehyde with hydrogen and ammonia or an ammonia-liberating compound, in the presence of a hydrogenation catalyst and an amine, wherein the molar ratio of the amine to the aromatic dialdehyde is no less than 1:4 at the start of the reaction.
US11066374B2	Method for producing kakeromycin and derivatives thereof Provided is a production method of kakeromycin and a derivative thereof showing an antifungal activity and cytotoxicity and expected as a new antifungal agent or anticancer agent, by chemical synthesis. A production method of a compound represented by the formula (1): wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; and n is 0 or 1, or a salt thereof, including a step of subjecting a compound represented by the formula (2): wherein R and n are as defined above, or a salt thereof, to an oxidation reaction.
US11066372B2	Deuterated benzimidazole compound and medical use thereof The present invention relates to a medicament for treating or preventing a disease involving Na channel, for example, neuropathic pain, nociceptive pain, inflammatory pain, small-fiber neuropathy, erythromelalgia, paroxysmal extreme pain disorder, dysuria, or multiple sclerosis, comprising a compound of formula (I) wherein R1a, R1b, R1c, and R1d are hydrogen, halogen, cyano, C1-4 alkyl, C1-4 alkoxy, etc., provided that at least one of R1a, R1b, R1c and R1d is the above C6-10 aryl, C6-10 aryloxy, etc., R2 and R3 are hydrogen, C1-6 alkyl, C3-10 cycloalkyl, etc., R4 is hydrogen, C1-6 alkyl, C3-7 cycloalkyl, etc., m is 0, 1, or 2, L is CR7R8, R7 and R8 are hydrogen, hydroxy group, C1-4 alkyl, C1-4 alkoxy, etc., or a pharmaceutically acceptable salt thereof.
US11066366B2	Hydrophilic fentanyl derivatives Various fentanyl derivatives are described. The derivatives exhibit high binding affinity to opioid receptors, but also have decreased blood brain permeability as compared to standard fentanyl. This, the resulting derivatives can be less addictive than standard fentanyl. Methods of making such derivatives are also disclosed in this document.
US11066364B2	NLRX1 ligands Provided are compounds that target the nucleotide-binding oligomerization domain, leucine rich repeat containing X1 (NLRX1) pathway. The compounds can be used to treat multiple conditions, including inflammatory, immune-mediated, and/or chronic inflammatory gastrointestinal diseases; systemic immune-mediated diseases; cancers; and infectious diseases.
US11066362B2	Method for producing pyrrole compound The present invention provides a production method of a 3-cyanopyrrole compound possibly useful as an intermediate for pharmaceutical products. A production method of compound (II) including subjecting compound (I) to a reduction reaction, in which the aforementioned reduction reaction is continuous hydrogenation reaction in a fixed bed reactor filled with a supported metal catalyst. A production method of compound (III) including subjecting compound (I) to a reduction reaction followed by a cyclization reaction, in which the aforementioned reduction reaction is continuous hydrogenation reaction in a fixed bed reactor filled with a supported metal catalyst.
US11066358B1	Compositions of essentially pure form IV of N-((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof The present disclosure relates to: a) a crystalline composition of essentially pure Form IV of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide; b) pharmaceutical compositions comprising the crystalline composition of essentially pure Form IV of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide, and, optionally, a pharmaceutically acceptable carrier; and c) methods of treating a tumor, a cancer, or a Rasopathy disorder by administering the crystalline composition of essentially pure Form IV of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide to a subject in need thereof.
US11066357B2	Benzoannulene derivatives as antiviral agents The present disclosure is concerned with benzoannulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US11066354B2	Process for mono N-alkylation of aminophenol The invention relates to a process for the preparation of a compound represented by formula (I) wherein X is selected from the group consisting of —H, -halogen, linear or branched C1-C7 alkyl group, linear or branched C1-C5 alkoxy group, —NO2 and —CN and Y is a linear or branched C1-C7 alkyl group, comprising the steps of: 10 a) reacting a compound represented by formula (II) with a compound represented by (III) to obtain an intermediate product, wherein X is as defined with respect to formula (I), wherein Z is H, CH3 or C2H5, b) reacting the intermediate product of step a) with a compound represented by Y2SO4 (IV) wherein Y is as defined with respect to formula (I) to obtain a salt and c) hydrolyzing the salt of step b) to obtain the compound of formula (I).
US11066353B2	Antigen delivery vectors and constructs The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
US11066352B2	Processes of making L-ornithine phenylacetate Embodiments of the present disclosure are related to improved processes for making L-ornithine phenylacetate without using any silver salts or forming any L-ornithine intermediate salts, such as a benzoate salt. The present processes may be used in the commercial scale manufacturing of L-ornithine phenylacetate with high yields and low impurities.
US11066346B2	Method and system for obtaining one or more olefins The invention relates to a method (100, 200) of obtaining one or more olefins, in which, using an oxidative coupling of methane (10), a gas mixture comprising hydrogen, methane, carbon monoxide and higher-boiling hydrocarbons than methane is formed and is subjected to a low-temperature separation (1-5), characterized in that the low-temperature separation (1-5) is conducted using a rectification column (2) having a first separation region (21), a second separation region (22) arranged above the first separation region (21), and a condenser-evaporator (23), wherein the gas mixture is cooled, fed at least partly as first separation feed into the first separation region (21) and subjected to a first rectification in the first separation region (21) to form a first tops gas and a first bottoms liquid, wherein, using a first proportion of the first tops gas in the condenser-evaporator (23), a condensate which is recycled to the first separation region and, using a second proportion of the tops gas, a second separation feed which is fed into the second separation region (22) are formed, and wherein the second separation feed is subjected to a second rectification in the second separation region to form a second tops gas and a second bottoms liquid.
US11066342B2	Fertilizer composition and methods of making and using same In accordance with the present invention, disclosed herein is a fertilizer core and fertilizer granule and methods related thereto. The fertilizer core particle has an outer surface and comprising one or more fertilizer additives, one or more binders, and one or more pH buffering agents, and wherein the fertilizer core particle comprises from about 10 wt % to about 99 wt % of the one or more binders.
US11066339B2	Article for high temperature service An article comprises a substrate comprising a ceramic matrix composite; a first layer disposed over the substrate, the first layer comprising a substantially interconnected silicon source material, and a secondary material; and a second layer disposed over the first layer, the second layer comprising a membrane material in mass transfer communication with the silicon source material.
US11066336B2	Honeycomb structure A honeycomb structure includes honeycomb segments, bonding layers and a circumferential wall. The bonding layers include bottomed-hollow voids which extend toward an internal side in an axial direction from an end face of the honeycomb structure and which are formed at at least one of intersections, and a ratio of a depth of each void in the axial direction to a length of each honeycomb segment in the axial direction is 5% or more.
US11066335B2	Articles for creating hollow structures in ceramic matrix composites The present disclosure relates to a method of fabricating a ceramic composite components. The method may include providing at least a first layer of reinforcing fiber material which may be a pre-impregnated fiber. An additively manufactured component may be provided on or near the first layer. A second layer of reinforcing fiber, which may be a pre-impregnated fiber may be formed on top the additively manufactured component. A precursor is densified to consolidates at least the first and second layer into a densified composite, wherein the additively manufactured material defines at least one cooling passage in the densified composite component.
US11066334B2	Binderless cBN sintering with cubic press A method of sintering a binderless cBN body includes providing a boron nitride particle mixture into a pressure chamber, the boron nitride particle mixture having a first type of boron nitride particles and boron nitride filler particles, and the boron nitride filler particles having a different size and/or type than the first type of boron nitride particles, and sintering the boron nitride particle mixture in the pressure chamber to form the cBN body by generating a pressure in the pressure chamber of less than 7.7 GPa and heating the boron nitride particle mixture to a temperature ranging from about 1900° C. to about 2300° C., wherein the cBN body has a density of at least 97 percent.
US11066332B2	Dielectric ceramic composition and ceramic electronic component According to the present invention, a dielectric ceramic composition, which can be fired in a reducing atmosphere, has a high dielectric constant, has an electrostatic capacity exhibiting little change, when used as a dielectric layer of a ceramic electronic component such as a laminated ceramic capacitor even under a condition of 150 to 200° C., and has small dielectric losses at 25° C. and 200° C., can be provided.
US11066330B2	Copolymers having a gradient structure The present invention relates to a copolymer, especially for use as a dispersant for solid particles, in particular for use as dispersant for mineral binder compositions, having a polymer backbone and side chains bonded thereto, comprising at least one ionizable monomer unit M1 and at least one side chain-bearing monomer unit M2, wherein the copolymer has a gradient structure in at least one section A in a direction along the polymer backbone with regard to the ionizable monomer unit M1 and/or with regard to the side chain-bearing monomer unit M2.
US11066329B2	Antireflective glass substrate and method for manufacturing the same A method for manufacturing antireflective glass substrates by ion implantation, comprising selecting a source gas of N2, or O2, ionizing the source gas so as to form a mixture of single charge and multicharge ions of N, or O, forming a beam of single charge and multicharge ions of N, or O by accelerating with an acceleration voltage A between 13 kV and 40 kV and setting the ion dosage at a value between 5.56×1014×A/kV+4.78×1016 ions/cm2 and −2.22×1016×A/kV+1.09×1018 ions/cm2, as well as antireflective glass substrates comprising an area treated by ion implantation with a mixture of simple charge and multicharge ions according to this method.
US11066324B2	Lithium containing glasses A glass article including, on an oxide basis, from 60 mol % to 74 mol % SiO2, from 7 mol % to 18 mol % Al2O3, from 3 mol % to 16 mol % B2O3, from 0 mol % to 6 mol % Na2O, from 0 mol % to 5 mol % P2O5, from 5 mol % to 11 mol % Li2O, less than or equal to 0.2 mol % SnO2, and from 0.5 mol % to 6.5 mol % divalent cation oxides. The glass article has a molar ratio of Al2O3:(R2O+RO) greater than or equal to 0.9, where R2O is a sum of alkali metal oxides in mol % and RO is a sum of divalent cation oxides in mol %.
US11066321B2	Mold, molding apparatus, production method of molded body, and molded body The present invention relates to a mold including a master mold having a first region master mold molding surface having a shape corresponding to a first region of a molded body, and a second region master mold molding surface having a shape corresponding to a second region of the molded body, and in which the master mold includes: an inner mold having the first region master mold molding surface; an outer mold having an accommodating concave portion capable of accommodating the inner mold therein and the second region master mold molding surface on at least a part of an outer edge of the accommodating concave portion; and a buffer material provided between the inner mold and a bottom surface of the accommodating concave portion, the buffer material being pressed and deformed with relative movement of the inner mold and the outer mold.
US11066315B2	Induced sludge bed anaerobic reactor system An induced sludge bed anaerobic reactor system that includes at least two stages of bioreactor processing, a first-stage feeding system, a second-stage feeding system, a pH balancing system, an effluent recirculation system, a gas management system, and a controller. In addition, any given stage of reactor processing may be comprised of a plurality of reactors that are configured to operate in parallel with each other.
US11066306B2	Diatomaceous energy storage devices A printed energy storage device includes a first electrode, a second electrode, and a separator between the first and the second electrode. At least one of the first electrode, the second electrode, and the separator includes frustules, for example of diatoms. The frustules may have a uniform or substantially uniform property or attribute such as shape, dimension, and/or porosity. A property or attribute of the frustules can also be modified by applying or forming a surface modifying structure and/or material to a surface of the frustules. A membrane for an energy storage device includes frustules. An ink for a printed film includes frustules.
US11066304B2	Polymer grafted graphene and method for preparation thereof The present invention provides graphene in which a polymer having a functional group capable of improving the dispersibility of graphene is bonded to the surface of the graphene. The present invention also provides a method for preparing the graphene described above.
US11066298B2	Systems and methods for production and separation of hydrogen and carbon dioxide The present disclosure relates to systems and methods useful for providing one or more chemical compounds in a substantially pure form. In particular, the systems and methods can be configured for separation of carbon dioxide from a process stream, such as a process stream in a hydrogen production system. As such, the present disclosure can provide systems and method for production of hydrogen and/or carbon dioxide.
US11066297B2	MEMS packages and methods of manufacture thereof Microelectromechanical systems (MEMS) packages and methods of manufacture thereof are described. In an embodiment, a method of manufacturing a MEMS package may include attaching a MEMS structure having a capping structure thereon to a device wafer comprising a plurality of first devices formed therein to form a wafer level MEMS package; and singulating the device wafer having the MEMS structure attached thereto to form a plurality of chip scale MEMS packages.
US11066294B2	Micro-electro-mechanical actuator device of piezoelectric type and apparatus integrating the micro-electro-mechanical actuator device A micro-electro-mechanical (MEMS) actuator device includes a frame, and a first functional sub-structure positioned within the frame and mechanically coupled thereto by supporting elements. The first functional sub-structure is subdivided into first and second portions. The first portion is subdivided into first and second sub-portions separated from one another by a first through trench, and the second portion is subdivided into first and second sub-portions separated from one another by a second through trench. First and second piezo-electric structures are respectively carried by the first and second sub-portions of the first portion. Third and fourth piezo-electric structures are respectively carried by the first and second sub-portions of the second portion. A third through trench extends between the frame and the first functional sub-structure except for regions in which the supporting elements are present.
US11066292B2	Device for transferring a fluid to a ship A device (1) for transferring a fluid from a mooring area to a ship is specified. The device (1) comprises an articulated supporting structure (2), which has at least one first and one second support (3, 4, 5), which are connected pivotably to one another by at least one pivot joint (6, 7) and which each have a longitudinal axis, wherein the first support (3) is fixed on the mooring area in such a way that the longitudinal axis of said support can be rotated substantially vertically and the first support (3) can be rotated about the longitudinal axis thereof, and wherein the second support (4, 5) is pivotable in a vertical plane. The device (1) furthermore comprises at least one guide element (8), which is fixed on the supports (3, 4, 5) or on the at least one pivot joint (6, 7), and a first flexible line (9), which is supported by means of the guide element (8) and is guided substantially in the vertical plane. The device furthermore comprises a second flexible line (10), which is arranged substantially in a horizontal plane around the first support (3) and is connected to the first flexible line (9) by means of a rigid tube section (13) connected in a fixed manner to the first support (3).
US11066291B1	Flush and winterizing system A system and parts of a system that can be used to introduce fluid into a closed circuit. The system includes a valve having an inlet, an outlet, a flush inlet; a spool located in a valve body and coupled to a handle, and the spool can selectively, by the positioning of the handle, direct flow between the inlet, outlet, and flush inlet. The system also includes an uptake conduit comprising a valve connector that is configured to couple with the flush inlet, and a conduit, that is configured to allow fluid to flow therethrough. Additionally, the system has a system attachment having a system connector and a valve connector, and the uptake conduit and the system attachment are coupled to the valve.
US11066290B2	Electric fuel shutoff device An electric fuel flow control device for use with oil and gas equipment, such as fueling systems for frac pumps. The electric fuel flow control device includes a battery, control circuitry, an enclosure that encloses the control circuity, and includes an electric fluid sensor, a valve, a beacon light, a status light, a button, an adapter cap enabling connection to a fuel tank, and a mandrel. The electric fuel flow control device may be used as a primary fuel flow control device or a backup fuel flow control device.
US11066284B2	Article transport vehicle An object is to provide an article transport vehicle which includes one or more fall preventing members while reducing any increase in complexity of the arrangement. An article transport vehicle includes a travel portion, a support portion, and a moving mechanism. The moving mechanism is configured to move the support portion to a projected position and to a retracted position. The support portion includes a support member configured to support a container, a movable member configured to be moved along a lateral width direction by the moving mechanism, and a vertically moving mechanism configured to move the support member along the vertical direction with respect to the movable member. The article transport vehicle further includes one or more fall preventing members configured to prevent a lid of a supported container from falling, and a movement coupling mechanism configured to move the one or more fall preventing members when the support member is moved.
US11066277B2	Gap-reducing sill assembly for an elevator car An illustrative example elevator sill assembly includes a sill plate and at least one support arm secured to the sill plate. A mounting bracket is configured to be mounted to an elevator car. The support arm is supported on the mounting bracket to allow the support arm to pivot relative to the mounting bracket. At least one linear actuator has a moving portion that moves in a vertical direction to cause the at least one support arm to pivot relative to the mounting bracket to thereby cause the sill plate to pivot from a stored position to an actuated position.
US11066271B2	Method for operating a textile machine and a textile machine A method for operating a textile machine with several identical workstations which each have a basic requirement for negative pressure for regular production operation and an additional requirement for negative pressure following an interruption to production at the workstation, and with a vacuum system with limited suction force to exert the negative pressure on the workstations. A minimum negative pressure (pmin) is set and the number workstations simultaneously supplied with additional negative pressure is limited so that the minimum negative pressure (pmin) is always met. In accordance with the invention, a sub-negative pressure (psub) is specified which is below the minimum negative pressure (pmin) and, if a specified event occurs, the number of workstations simultaneously supplied with additional negative pressure is temporarily limited so that the sub-negative pressure (psub) is always met.
US11066264B2	Method for automatically replacing reels in an unwinding assembly and relative unwinding assembly A method for automatically replacing reels in an unwinding assembly capable of carrying out the handling operations of the reels, as well as preparing and joining the tail of the web of the finished reel with the head of the web of the new reel in a simple, efficient way, reducing the risk of malfunctions and maintaining the correct orientation of the new web as that of the finished web.
US11066263B2	Sheet conveying device and image forming apparatus incorporating the sheet conveying device A sheet conveying device, which is incorporated in an image forming apparatus, includes a first detector to detect an angle deviation of a recording medium to a sheet conveying direction, a second detector to detect a lateral shift of the recording medium to a width direction, a third detector to detect at least one of the angle deviation and the lateral shift after correction of the angle deviation detected by the first detector and the lateral shift detected by the second detector, and a rotary body to perform a primary movement by (1) rotating in the sheet conveying direction and returning to a reference position and by (2) moving in the width direction and returning to the reference position, and a secondary movement by performing at least one of (1) and (2) after the primary movement.
US11066262B2	Apparatus and method for singling sheet material A singling apparatus and a system for singling sheet material comprises a sheet store for receiving a sheet stack of sheets to be singled. The sheet store includes a singling gap, which is formed and arranged to deliver a sheet out of the sheet store to a transport mechanism. The singling apparatus comprises further a singling device comprising a rotating separation roller wherein the separation roller comprises partially on its rotational surface a contact area to periodically contact and transport the sheet from the sheet store to the transport mechanism. A position control device of the singling apparatus is coupled to the separation roller and comprises an alignment indication being in correlation with an angle position of the contact area of the separation roller and indicates the alignment of the contact area to the singling gap and/or the sheet.
US11066261B2	Sheet container and image forming apparatus A sheet container to contain a sheet includes a support unit including a plurality of engaged portions and supports the contained sheet, a moveable regulation unit that contacts a sheet end to regulate the sheet in position. The regulation unit includes an operating member held by a holding member and a fixing member movable with the operating member covered by a cover. The fixing member is movable between an engaging position at which the fixing member engages with one of the plurality of engaged portions and a non-engaged position at which the fixing member does not engage with one of the plurality of engaged portions. The operating member is engageable with the cover. The regulation unit is kept fixed to the support unit by the fixing member engaging with one of the plurality of engaged portions, with the cover engaging with the operating member.
US11066259B2	Dust control systems for bulk material containers Controlling the dust emissions from the discharge of bulk materials from a container provides many benefits. A container engages a support structure that includes a frame. The frame includes a dust control enclosure coupled to an outlet or a hopper at the top of the frame and the container or a discharge gate of the container. The dust control enclosure comprises a collapsible and flexible material so that a tight seal is formed between the container and the hopper or the outlet of the frame. Dust from the discharged of the bulk material from the container is contained within the support structure. A dust control panel may also be disposed at the top of the frame to prevent any dust from migrating through the frame. The container may comprise a plurality of dust enclosure panels to further prevent the escape of dust during discharge of the bulk material.
US11066258B2	Control system and control method for rotary car dumpers This invention relates to a control system and method for rotary car dumpers comprising a positioning car, silos and feeders. Such control system comprises three integrated and communicating controls in closed grid, that is, the positioning car control, the silos level control and the feeder flow control. In this way, with the data of these controls, the rotary car dumpers control system is configured to maintain the level of silo at maximum, performing changes in the cycle time by controlling the positioning car to maintain the level of silos and thus achieve maximum productivity of the equipment.
US11066257B2	Container transport system A container transport system and method of operation can include: providing a vehicle having a subframe assembly coupled thereto, the subframe assembly including a lifting arm and a clamping arm; clamping the clamping arm onto a corner fitting of a cargo container; raising the lifting arm for raising a portion of the cargo container; inserting a jack stand below the cargo container; lowering the lifting arm for tilting the cargo container on the jack stand, the jack stand configured as a fulcrum; positioning a container trailer below the cargo container; and raising the lifting arm for pivoting the cargo container on the jack stand and lowering the cargo container onto the container trailer.
US11066256B2	Grain bin powersweep with sump shaft aperture sealing cover plate assembly An unload conveyor and a sweep conveyor can be positioned below and above a floor of the grain bin, respectively. A below floor gearbox and an above floor gearbox can be positioned below and above a sloped wall, respectively, of a sump. The sloped wall can be designed to shed grain toward a sump basin. A coupling shaft can extend through a non-circular sump shaft aperture in the sloped wall to couple the below floor gearbox to the above-floor gearbox. The coupling shaft can extend vertically. A pair of seal cover plates can form a horizontal wall extending perpendicular to the coupling shaft. The horizontal wall can have a circular sealing aperture therein and through which the coupling shaft extends. A washer can be provided adjacent the circular sealing aperture that can be free to move laterally with wobbling of the coupling shaft.
US11066253B2	Container dumping module A container dumping module comprises a frame assembly and a conveyor bed with plurality of rollers supported on the frame assembly. A cradle assembly positioned on the frame assembly. The cradle assembly comprises a pair of lower and upper guide support plates to support a container in a home position, a transit position, and a work position. A drive assembly mechanically coupled to the frame assembly and configured to drive the cradle assembly to one of the home position, the transit position, or the work position.
US11066252B2	Suction gripping device A suction gripping device includes a support arm and a head with at least one suction gripping element mounted translatably along the support arm. The head has an inlet and a channelling system to place the inlet and the gripping element in communication. The device further includes a manifold maintained in depression, a seal along a side of the device to maintain the inside of the manifold in depression, and a fluid distributor group interposed between the inlet in the head and the side and borne by the head so as to be slidable along the side. A spacer is provided for distancing and keeping a portion of the seal distanced from the side so as to maintain the channelling system in depression for activation in suction of the gripping element.
US11066250B2	Apparatus for unscrambling randomly arranged containers comprising extraction means independent of each other An apparatus for unscrambling articles, in particular containers fed randomly to an inlet of the apparatus, includes a transport system for transporting the articles fed to the inlet, devices for picking and releasing the articles configured to pick up the articles arranged randomly on the transport system and release them to an extraction system with a predefined orientation and/or position, a detection system designed to detect the position and the arrangement of the articles in transit on the transport system and to provide the information for controlling the pick and release devices, and a unit for processing and controlling the components and the drives of the apparatus. The extraction system includes a plane for supporting the containers being extracted and means for extracting the articles, designed to pick up the articles released by the pick and release devices and transport them on the plane towards the outlet of the apparatus.
US11066246B2	Extendible conveyor with irregular parcel handling An extendible conveyor system having an extendible conveyor configured to extend into a container, at least one belt on the extendible conveyor configured to transport an irregular parcel from the container to a base end of the extendible conveyor, and a transfer mechanism configured to move the irregular parcel from the at least one belt to a shelf. A method includes transporting an irregular parcel on the at least one belt from the container to a base end of the extendible conveyor and moving the irregular parcel from the at least one belt to a shelf using the transfer mechanism.
US11066241B2	Two-stage picking by means of sorter having high-dynamic sorter trays It is disclosed storage and order-picking system, comprising: a control device configured for performing two-stage picking of articles, wherein the two-stage picking comprises a first article-orientated picking stage, and a second order-orientated picking stage; a warehouse, wherein the articles in the warehouse are stored in storage containers in an article-pure manner, and wherein the articles are retrieved in an article-orientated manner from the warehouse in the first picking stage; a sorter comprising: a loop-shaped main line operated continuously; at least one branch line, wherein each of the branch lines is coupled, preferably mesh-shaped, to the main line and is operable discontinuously; and a plurality of sorter trays, wherein each of the trays is configured to be moved along the lines and to be fed into and out from the main line; one or more separation stations, wherein each of the separation stations: is coupled to the main line via one of the branch lines; is coupled to the warehouse for being supplied with storage containers; and is configured for reloading the articles from the storage containers onto the trays for transferring the articles in the first picking stage in accordance with order lines and/or individually onto respectively one of the trays located on the one of the branch lines; and a plurality of automatically and/or manually operated target locations for the second picking stage, wherein each of the target locations is coupled: to one of the branch lines; and/or directly to the main line.
US11066240B1	Automated pharmacy system An automated pharmacy system includes a storage rack; bins to be stored within the storage rack and to store one or more medication packages, each of the bins having a separate bar code; a kiosk having an interface manually manipulated by a user to receive identifying information of the user; a central computer in data communication with the kiosk; a locker unit having lockers, the lockers having an identification reader to unlock the lockers based on receiving correct identifying information and lockers having a bar code; a robotic arm manipulated by the central computer; a rail positioned on a ground surface; and a bar code reader secured to the robotic arm.
US11066234B2	Components and end walls for freight container The present disclosure provides for end walls for a freight container. The end walls include those for a rear wall and a front wall for the freight container. The rear wall includes rear corner posts each having a recess to receive a rear door hinge in the rear corner post and a corner fitting mounting block. The rear wall further includes corner fittings each having a receiving block, a sill member connected to a first rear corner posts by a member hinge, a header member connected to a second rear corner posts by a member hinge, a first rear wall door and a second rear wall door. The front wall includes front corner posts having gussets, anti-racking blocks, corner fittings with receiving blocks, a sill member, a header member and a front wall door.
US11066232B2	Beverage preparation capsule A capsule for preparing beverages in an automatic beverage preparation device, comprising an insert, which divides the capsule inner volume into an upper chamber intended to contain a beverage preparation substance, and a lower chamber for beverage collection and outflow. The insert comprises a relatively rigid disc, which is provided with a number of passages designed to establish a communication between the upper chamber and the lower chamber, and has, on the lower face of the disc facing the lower chamber, some beverage outflow channels communicating with the upper chamber through the passages. The insert further comprises a membrane permanently connected to the lower face of the disc except for one or more areas so as to define, together with the areas, respective membrane valves configured to open under the effect of the beverage pressure, so that the beverage flows out from the upper chamber to the lower chamber, and to close again when the effect of the beverage pressure ends.
US11066221B2	Package with unique opening device and method for opening package A package and method for opening the package are disclosed. The package includes a first film and a second film forming an enclosure and at least one tab area and defining a package periphery, the enclosure defining an interior volume configured to receive a product. The package further includes first and second breachable bubbles formed within first and second tab portions of the at least one tab area. Upon application of pressure by a user, the first and second breachable bubbles breach. The package may be alternated between a first position, wherein the first tab portion and the second tab portion are substantially sealed from each other to facilitate breaching, and a second position, wherein the first tab portion and the second tab portion are in fluid communication with each other.
US11066219B1	Portable drinking bottle with an auxiliary casing for articles The present invention is a portable drinking bottle for carrying re-usable articles like spoons, fork and knives and preventing the need of disposable polymeric articles and hence save environment. Portable drinking bottle includes a main casing and an auxiliary casing, an inner closure and an outer closure. Auxiliary casing is introduced in main casing to form a cavity therebetween so that drinking liquid can be filled therewithin. Main casing and auxiliary casing are enclosed by an inner closure that has a central aperture to insert in and remove articles from auxiliary casing. Inner closure also has a spout which is in connection with cavity and hence enables drinking of liquid. Also, auxiliary casing can be removed for cleaning or when not desired thus providing a simple structure.
US11066217B2	Twist lid for beverage container A lid for a beverage container includes a lid cover, a lid base and a twist ring. The twist ring is rotationally secured to the lid base. The lid cover has a first latch member, the lid base has a first mating member, and the twist ring has a second latch member that mates with the first latch member and a second mating member that mates with the first mating member to allow the twist ring to rotate with respect to the lid base to disengage the second latch member from the first latch member.
US11066216B2	Flip lid and container including the same A flip lid including a lid body is provided. The lid body can include a outlet through the lid body. A flap is rotatably connected to one side of the lid body. A rotating element is rotatably connected to the other side of the lid body. A resetting member urges the rotating element to a sealing position to seal against the outlet. An actuating member is disposed on a side of the rotating element facing the outlet. The flap includes an actuating protrusion. During a rotation of the flap, the actuating protrusion is in contact with the actuating member to cause the rotating element to rotate away from the sealing position to an unsealing position to break the seal with the outlet.
US11066215B2	Tattoo bottle with secure lid A tattoo ink bottle is provided having an openable sanitary cap that is configured for one-handed operation and a tight closed seal.
US11066214B2	Additive container An additive container is configured to contain an additive to be added to a defibrated material therein and to be coupled to an intake port for introducing the additive of an additive supply device. The additive container includes a container that includes a discharge port and contains the additive, and a first shutter member that opens and closes the discharge port. The first shutter member enters an open state by rotating the container in a first direction around a central axis of the discharge port with respect to the first shutter member, and the first shutter member enters a closed state by rotating the container in a second direction opposite to the first direction with respect to the first shutter member from the open state.
US11066206B2	Package, and methods for producing and for using self-adhesive Provided is a method for producing a self-adhesive to be arranged on a package comprising a space to store contents and an opening by which the space and an outside communicate, wherein the opening is repeatedly openable and sealable by the self-adhesive that consists of a cross-linking material of a resin composition containing a (meth)acrylic acid ester copolymer resin having a glass transition temperature of −22.8° C. or more, and a crosslinking agent. The method comprises making the resin composition that contains the (meth)acrylic acid ester copolymer resin, and the crosslinking agent, the resin composition being either emulsion or dispersion; and cross-linking the resin composition.
US11066205B2	Hygienic labeling machine A high speed labeling machine especially designed for use in food or pharmaceutical processing environments. It can be periodically washed down in accordance with applicable governmental standards without entry of washing fluid into an interior of an enclosure assembly containing servo motors and the electronics for driving shafts that penetrate through a wall of the enclosure assembly and on which a label web supply reel and a web take-up reel are removably mounted. A plurality of idler rollers and a pinch roller are used to route the label carrying web from the supply reel, over an edge of a peel plate, where the labels are separated from the web, and back to the web take-up reel. The idler rollers and the pinch rollers are journaled on shafts in a way precluding entry of wash fluids into their interior. The enclosure assembly is cantilever-mounted on a jack stand for vertical adjustment relative to items to be labeled.
US11066202B2	Bagging machine and method A product bagging assembly and method of manipulating a web material bag that is operable to create a bag opening that is greater than six inches and which is operable without substantially detracting from product throughput associated with use and operation of the product bagging assembly. In a preferred embodiment, the bag opening/closing assembly includes a first actuator and a second actuator that are connected to one another such that a position of one of the actuators can be manipulated by operation of the other actuator. The product bagging assembly can be provided as a kit configured for plug and play operation with previously provided bag and product delivery systems.
US11066201B2	Baling press for cotton gin trash and other biomass feedstock and methods of using the same The present invention generally relates to a baling press for baling cotton gin trash and other particulate biomass feedstock. The baling press generally comprises an infeed chute assembly, a compression ram assembly, an extrusion chamber assembly, a strapping storage and dispensing assembly, and a strapping insertion assembly. The present invention also relates to methods of producing a bale with the baling press and a bale generated by said baling press and described methods.
US11066196B2	Weighing and packaging apparatus A weighing and packaging apparatus (10) includes a packaging unit (14), a weighing unit (11), and a frame (70). The packaging unit (14) includes a film transport mechanism (30) that transports a film (F) in a film transport direction, a detachable former (22), a former seat (82) that supports the former (22), and a sealing mechanism (50). The weighing unit (11) is positioned on an upper side in a vertical direction of the packaging unit (14), and supplies articles (A) to be packaged to the packaging unit (14). The frame (70) supports at least the weighing unit (11), and includes legs including a first front leg (71a), a first back leg (71b), a second front leg (72a), and a second back leg (72b). A movable portion (89) including the former seat (82) moves in a maintenance mechanism movable space (PM) when the former (22) is detached. All of the legs are located so as to avoid a leg prohibited space (PP).
US11066191B2	System and method for detecting substances from spectral signatures A system and method for detecting or identifying substances based on spectral response signatures is provided. The system utilizes IR imagery, singularly or stored in a database, in operative communication with a database or library of known spectral response signatures. The system correlates the spectral response signature detected, or inherent, in an image or image library, with the set of known signatures in the spectral database. The system generates a report of the substances or chemical compounds present in at least a portion of the image. The system can also query a database of IR products for an area of interest, and return results in a report or via an interactive tool, for IR products containing specific IR spectral results.
US11066190B2	Method for deploying a satellite constellation A method of deploying a constellation of satellites includes using a single launch vehicle to deploy a plurality of satellites at an initial altitude on a same initial orbit, controlling said satellites such that an altitude of some of the satellites is modified while their inclination relative to an equatorial plane and a type of trajectory, of the some of the satellites, remains identical so that each satellite reaches a drift altitude selected from a drift set, with orbits of various satellites shifting relative to one another, and controlling the satellites to be moved sequentially in order to reach a same final altitude, said sequential movement being performed in such a manner that the satellites describe final orbits having trajectories with a same angle of inclination relative to the equatorial plane, a same apogee and perigee, and the same final altitude but presenting distinct longitudes for ascending nodes.
US11066183B2	Ground handling facility and method for passenger-transporting aircraft A ground handling facility (1) for passenger-transporting aircraft (100), in particular vertical takeoff and landing multicopters, including: at least one first platform (2) which is designed as a landing platform (2) for a passenger-transporting aircraft (100), wherein a) the at least one first platform is simultaneously designed as a takeoff platform for a passenger-transporting aircraft (100), or b) wherein a second platform (3) is provided which is designed as a takeoff platform (3) for a passenger-transporting aircraft (100); at least one region (4) which is designed as weather protection for the passengers and the aircraft (100), in particular by provision of a canopy; and at least one conveying device (5.1; 5.2; 5.3) for the aircraft (100) that is designed to move the aircraft (100) from the landing platform (2) through the region (4) to the takeoff platform (3), in which region there is provided at least one station (6.1-6.4) which is configured for a predetermined interaction with the aircraft (100).
US11066181B2	System and method of determining and displaying procedures for an engine-out takeoff for an aircraft A system and method of displaying an Engine Failure Awareness Chart (EFAC) for aircraft with at least one engine out is shown and described herein. The EFAC may display lines and zones indicative of levels of risk of obstacles on the ground. The obstacles may be either man-made or natural structures. The EFAC may update continuously providing the pilot with a real-time awareness of the risks around the aircraft during an engine failure. Using the EFAC the pilot may navigate the aircraft to a landing area or back to the airport for landing.
US11066175B2	Cinched parachute A cinched parachute is disclosed. In various embodiments, a cinched parachute as disclosed herein includes a canopy comprising one or more sections of canopy material, and a device integrated with the canopy that controls dimensions of the canopy material. For example, in some embodiments the device may be used to control the size of an opening atop the parachute.
US11066174B2	Movable ottoman for an aircraft seat An aircraft seating unit includes a base, a seat coupled to the base, a housing coupled to the base and enclosing frame elements of at least one of the base or the seat, and an ottoman. The housing defines a recess at a location below and to a rear of the seat. The ottoman is disposed within the recess. The ottoman includes a guide coupled to at least one of the frame elements, a slide translatable along the guide, a foot platform coupled to the slide, and an actuator positioned to facilitate selectively translating the slide along the guide to reposition the foot platform between a stowed position and a deployed position. The guide defines a translation axis that is angled relative to a vertical axis such that the foot platform moves both vertically and horizontally as the slide translates along the guide.
US11066170B2	Aircraft passenger seating unit and passenger seating arrangement A layout of passenger seats in an aircraft cabin including a first passenger seat positioned in a forward-facing direction and parallel to an aircraft longitudinal axis, and a second passenger seat positioned to one side of the first passenger seat, in a forward-facing direction, and at an angle with respect to the aircraft longitudinal axis, wherein the second passenger seat is angled toward the first passenger seat.
US11066168B2	Aircraft cargo roller panel A method includes receiving, at a controller, a signal from each load cell of a plurality of load cells coupled to an aircraft cargo roller panel of an aircraft. Each signal is indicative of a load experienced by the load cell when cargo is on the aircraft cargo roller panel. The method also includes determining, based on the signals, a weight of the cargo, a center of gravity of the cargo, or both.
US11066165B2	Self-enclosed air vehicle Vehicles such as unmanned air vehicles that are capable of movement from an open, flight configuration to an enclosed configuration in which all major flight components can be protected by an outer shell are disclosed. In the enclosed configuration, the vehicles can take on standard geometric shapes such as a rectangular prism, sphere, cylinder, or another shape, so as to not be recognizable as an unmanned air vehicle. Embodiments of vehicles can also include interchangeable and/or wireless motor arms, motor arms which are electrically connected to the remainder of the vehicle only when in an open configuration, remote controllers removably attached to the remainder of the vehicle, and clip or other attachment mechanisms for attachment to objects such as backpacks.
US11066162B2	Short takeoff and landing vehicle with forward swept wings A short takeoff and landing (STOL) vehicle which comprises a tail having a surface and a fuselage having a surface, where the tail and the fuselage have a continuity of surfaces where the surface of the tail is directly coupled to the surface of the fuselage. The vehicle further includes a forward-swept wing having a trailing edge and a rotor that is attached to the trailing edge of the forward-swept wing via a pylon, where the rotor has a maximum downward angle from horizontal that is less than or equal to 60° and the STOL vehicle takes off and lands using at least some lift from the forward-swept wing and at least some lift from the rotor.
US11066159B2	EVTOL aircraft using large, variable speed tilt rotors Apparatus, systems, and methods are contemplated for electric powered vertical takeoff and landing (eVTOL) aircraft. Such are craft are engineered to carry safely carry at least 500 pounds (approx. 227 kg) using a few (e.g., 2-4) rotors, generally variable speed rigid (non-articulated) rotors. It is contemplated that one or more rotors generate a significant amount of lift (e.g., 70%) during rotorborne flight (e.g., vertical takeoff, hover, etc), and tilt to provide forward propulsion during wingborne flight. The rotors preferably employ individual blade control, and are battery powered. The vehicle preferably flies in an autopilot or pilotless mode and has a relatively small (e.g., less than 45′ diameter) footprint.
US11066158B2	Low drag high capacity pitch bearing for rigid rotor aircraft A pitch bearing assembly for a rotor blade and a hub assembly of a rotary wing aircraft includes a single inner race. An inboard outer race surrounds an inboard portion of the inner race and includes a first inboard blade connector and a second inboard blade connector that are configured to connect to the rotor blade. An inboard bearing is disposed between the inboard portion of the single inner race and the inboard outer race and includes an elastomer. An outboard outer race surrounds an outboard portion of the single inner race and includes a first outboard blade connector and a second outboard blade connector that are configured to connect to the rotor blade. An outboard bearing is disposed between the outboard portion of the inner race and the outboard outer race and includes an elastomer.
US11066157B2	Constant-velocity joint link with reduced axial stiffness The present application provides a drive link for a constant-velocity joint of an aircraft rotor, the link connecting a drive hub attached to a driveshaft to a rotor yoke. The link comprises a leading bearing connected to the drive hub, a trailing bearing connected to the yoke, a central portion between the bearings, and a tension loop connecting the bearings. The tension loop is formed from a composite material and is formed as a continuous band. The tension loop transfers drive forces from the leading bearing to the trailing bearing for driving the yoke in rotation with the driveshaft.
US11066155B2	Unmanned aerial vehicle An unmanned aerial vehicle includes a housing assembly having a receiving space, a power assembly received in the receiving space, and a controlling assembly received in the receiving space and configured to control the power assembly. The housing assembly is provided with a flow passage penetrating an inside of the housing assembly, and the power assembly partially forms the flow passage. In the UAV, since the power assembly is mounted in the housing assembly, the propeller of the power assembly will not hurt person during the flight, thereby improving the safety performance while flying near the ground.
US11066153B2	Electric nose landing gear architecture A nose landing gear system is disclosed. In various embodiments, the nose landing gear system includes an electro-hydraulic actuator configured to raise and lower a nose shock strut assembly; a first electro-mechanical actuator configured to steer the nose shock strut assembly; and a second electro-mechanical actuator configured to open and close a fairing door.
US11066150B2	Propeller oil control system for aircraft turboprop engines A propeller oil control system for a turboprop engine of an aircraft includes an engine control unit and a propeller oil controller. The engine control unit is operable to determine a flight phase of the aircraft and is configured to supply control commands. The propeller oil controller is coupled to receive a supply of oil and to discharge the oil at a discharge oil pressure. The propeller oil controller includes an electrohydraulic servo valve that receives the control commands moves to a plurality of positions between a first position and a mid-position, and a plurality of positions between the mid-position and a second position. The engine control unit only commands the electrohydraulic servo valve to move out of the first position when the engine control unit determines the aircraft is conducting a take-off roll or the aircraft is in flight.
US11066141B2	Drive arrangement with an arresting element for propelling a boat System and methods are provided that relate to a drive arrangement for propelling a boat, in particular a kayak. In some embodiments, the drive arrangement can include an electric drive motor with a shaft and a receiving device for receiving the shaft. An arresting element can be provided for determining a first desired distance along the shaft between the receiving device and the drive motor.
US11066138B2	Floating structure installation system and floating structure installation method A floating structure installation system includes, on a body capable of traveling on water, a first cradle including a first holding part capable of holding a first portion having a submersible section to be located under the water surface during installation, and a second cradle including a second holding part capable of holding a second portion connectable to the first portion. At least one of the first cradle or the second cradle is movable on the body to connect the first portion held by the first holding part and the second portion held by the second holding part. The first holding part includes a first lifting unit for lifting and lowering the first portion.
US11066137B2	Marine structure The present invention relates to a marine structure comprising an external surface (50), a load (2, 20, 21, 22, 25) comprising a light source, said load having a first load terminal (2a) and a second load terminal (2b) adapted to be powered by an AC power source (1), said AC power source (1) having a first AC terminal (1a) electrically connectable to the surface (50) and a second AC terminal (1b), a first electrode (3) electrically connected to the first load terminal (2a), and a dielectric layer (4). The first electrode (3) and the dielectric layer (4) are arranged to form, in combination with the surface (50), a capacitor (6) for capacitive transmission of electrical power between the first electrode (3) and the surface (50). The second AC terminal (1b) and the second load terminal (2b) are arranged to be electrically connected to an external electrically conductive element (10, 11) insulated from the surface (50). The first load terminal (2a) is electrically insulated from the second load terminal (2b).
US11066135B1	Wave-generating watercraft with a wave forming fin A wave-generating watercraft includes a craft body having an installation space receiving a wave-generating unit. A telescopic drive is mounted within the installation space and is connected to a driven unit. A wave-forming fin is connected to the driven unit and is driven by the telescopic drive to move between extended and retracted positions. The telescopic drive is aligned with a front-rear direction of the craft body and is stretchable and retractable along the front-rear direction. The wave-forming fin protrudes from the installation space when the wave-forming fin moves to the extended position and is received in the installation space when the wave-forming fin retracts.
US11066127B2	Hydraulic valve unit, saddle-type vehicle A hydraulic valve unit includes a main oil passage configured to bring a side of a master cylinder and a side of a slave cylinder to communicate with each other, and a bypass oil passage configured to bypass a valve mechanism of the main oil passage, wherein the main oil passage and a main section of the bypass oil passage are disposed to be arranged with respective axes aligned with each other, and the main section of the bypass oil passage is disposed at the same height as the main oil passage or at a position higher than that of the main oil passage in a state in which a valve body is attached at a predetermined attachment position.
US11066125B2	Drive arrangement of a bicycle having a multi-sprocket arrangement A drive arrangement for a bicycle has a multi-sprocket arrangement for a rear wheel hub of the bicycle. The multi-sprocket arrangement comprises a plurality of sprockets with different diameters, wherein the sprockets each have a plurality of teeth which are separated by tooth spaces and which can be placed in engagement with a drive chain with wide and narrow chain links which follow one another alternatively in succession. On at least one sprocket, a corrective feature is provided which is designed such that the drive chain, as it revolves around a selected sprocket or during a sprocket changeover from a starting sprocket to a selected sprocket, is oriented, with regard to its wide and narrow chain links, in a predetermined chain link plate orientation relative to the teeth of the selected sprocket.
US11066120B2	Heated handgrips for a motorcycle Systems and methods for heating a handgrip of a vehicle. One system includes a first handgrip including a first heating element and a first temperature sensor and a second handgrip including a second heating element and a second temperature sensor. The system further includes a polarity switching circuit configured to provide power, when active in a first polarity, to the second temperature sensor and provide power, when in a second polarity, to the second heating element. The system includes an electronic processor configured to receive, when the polarity switching circuit is active in the first polarity, a temperature signal from the second temperature sensor, compare the temperature signal to a predetermined threshold, and set, in response to the temperature signal failing to exceed the predetermined temperature threshold, the polarity switching circuit to the second polarity.
US11066117B2	Bicycle inductive lock A bicycle inductive lock included a housing, a lock body, and a control circuit device. An annular latch and the lock body are disposed in the housing. A back cover is configured to close the housing. The annular latch has a first engaging groove, a second engaging groove and a third engaging groove. The lock body includes a first baffle that can be engaged in the first engaging groove or the second engaging groove, a second baffle that can be engaged in third engaging groove, and a speed reduction motor having a lever. The lever includes an angle control block and an eccentric paddle. The control circuit device includes an induction unit and a key fob. The key fob is configured to generate induction with the induction unit for transmitting a signal. With the above configuration, the bicycle inductive lock can sense the signal to be locked or unlocked.
US11066116B2	High-density bike rack system A high-density bike rack system includes a rack structure including: a first side configured to releasably engage a first bicycle, and a second side configured to releasably engage a second bicycle. A vertical displacement structure is configured to vertically offset at least one portion of the first bicycle with respect to at least one portion of the second bicycle.
US11066115B2	Training wheel system A training wheel system is provided that can improve packaging, shipping, and installation. The training wheel system includes a bracket for maintaining the orientation of a training wheel arm. In one form, the bracket can nest within a channel of a portion of the training wheel arm.
US11066114B2	Method for manufacturing automobile and compression holding jig A method for manufacturing an automobile includes placing a body on a pre-assembled underside part set, and then assembling the underside part set onto the body. The underside part set includes a rear suspension in which a spring and a shock absorber are arranged side by side, and the spring is brought into a compressed state in the underside part set before the body is placed on the underside part set.
US11066113B2	Galvanized wire ply for rubber track Endless elastomeric tracks include guide lugs disposed on an inner circumference, rubber tread lugs disposed on an outer circumference, and a thin band continuously extending in the circumferential direction which is disposed adjacent the outer circumference. The thin band has an exterior peripheral surface and an inner peripheral surface, and at least one galvanized wire ply is disposed between the exterior peripheral surface and an inner peripheral surface. The endless track further includes at least one primary cable of galvanized steel circumferentially reinforcing the thin band. In some aspects, the at least one galvanized wire ply includes a plurality of galvanized wires having a diameter of from about 0.15 mm to about 1.5 mm, from about 0.175 mm to about 1.3 mm, from about 0.20 mm to about 1.25 mm, from about 0.22 mm to about 1.2 mm, or even from about 0.25 mm to about 1.1 mm.
US11066112B2	Rear spoiler device for a utility vehicle A rear spoiler device for a utility vehicle has: a first roof air-guiding element for attaching to a first rear door and a second roof air-guiding element for attaching to a second rear doo. The two roof air-guiding elements are adjustable between a folded-in basic position and a driving position for the aerodynamic extension of the contour of a roof surface. A manual adjustment device for adjusting the first roof air-guiding element between the basic position and driving position. A coupling device is provided for coupling the pivoting movements of the roof air-guiding elements. The coupling device carries along the second roof air-guiding element during the adjustment of the first roof air-guiding element. The coupling device may be an overlapping element.
US11066108B2	Damper housing for vehicle A damper housing includes an upper-wall-plate and an upper-wall-reinforcement-plate. A plurality of collars through which fastening members for attaching a damper are interposed between the upper-wall-plate and the upper-wall-reinforcement-plate. The collars are disposed on a circumference around the damper. An upper section of the damper is fastened and fixed to the upper-wall-reinforcement-plate and the upper-wall-plate by the fastening members. A concave section is formed in at least one of the upper-wall-plate and the upper-wall-reinforcement-plate which are facing each other, the concave section being formed so as to protrude toward the facing upper-wall-plate or the upper-wall-reinforcement-plate. The concave section is disposed between the neighboring collars on the circumference on which the collars are disposed. The upper-wall-plate and the upper-wall-reinforcement-plate are coupled to the facing upper-wall-plate or the upper-wall-reinforcement-plate at the concave section.
US11066105B2	Utility vehicle A utility vehicle includes a plurality of ground engaging members and a frame supported by the plurality of ground engaging members. Additionally, the utility vehicle includes an operator area having a front seating section and a rear seating section.
US11066094B2	Steering column assembly A steering column assembly for a vehicle, with a vehicle-fixed storage element and on which a storage element is stored, wherein the receiving element is in operative connection with a steering wheel arrangement, an energy absorption device, an effective connection with the storage element and the receiving element and which provides for at least one elongated absorption member as well as at least one reduction member with a passage for the absorption member, through which the absorption member extends and which at least partially has a smaller Q1 cross section compared to a Q2 cross section compared to a cross section of at least one portion of an end-section of the absorption member.
US11066093B2	Steering column assembly having a locking assembly A steering column assembly includes a jacket assembly and a locking assembly. The jacket assembly is operatively connected to a mounting bracket. The jacket assembly is locking assembly operatively connected to at least one of the jacket assembly and the mounting bracket. The locking assembly includes a first member defining a first plurality of engagement members and a second member defining a second plurality of engagement members. Responsive to the locking assembly moving between an unlock position and a lock position, at least one of the first member and the second member moves along an arcuate path relative to the other of at least one of the first member and the second member.
US11066088B2	Detection and positioning method for train water injection port A detection and positioning method for a train water injection port includes: acquiring train water injection port video images, and performing threshold segmentation on the train water injection port video images to obtain binarized train water injection port video images; processing the binarized train water injection port video images and matching the processed binarized train water injection port video images with a train water injection port template image; detecting a position of the water injection port in the train water injection port video image and comparing the position with a pre-set position range where the water injection port is located; and if the position and the pre-set position range have been matched, then transmitting a matching valid signal to a mechanical device control module to control a mechanical device to move or stop and start or stop water injection.
US11066074B2	Control of an engine of a machine based on detected load requirements of the machine An electronic control unit to control an engine control module of an engine is disclosed. The electronic control unit may receive, from a load monitoring device, power command information associated with a load of an engine. The electronic control unit may determine, based on the power command information, a total power command of the engine. The electronic control unit may determine, based on the total power command, a target engine speed for the engine. The electronic control unit may cause an engine control module to control the engine to operate in association with the target engine speed.
US11066073B2	Vehicle control system, vehicle control method, and vehicle control program A vehicle control system includes a controller that sets a target area, and that executes a lane change of the host vehicle toward the set target area, the target area being an area which is a target for the host vehicle when performing the lane change to an adjacent lane which is adjacent to an own traffic lane on which the host vehicle is traveling, and a direction indicator controller that determines a timing for operating a direction indicator installed on the host vehicle on the basis of a relative relationship between the host vehicle and a vehicle that is traveling in front of or at rear of the target area set by the controller and the host vehicle.
US11066071B2	Coasting control method based on overspeed response and eco-friendly vehicle employing the same A coasting control method based on an overspeed response and an eco-friendly vehicle employing the same are provided. The coasting control method includes performing an active coasting control when an event for a section speed enforcement area is determined while a vehicle is traveling to allow the vehicle to pass through the section speed enforcement area based on a vehicle position at an event occurrence time.
US11066066B2	Hybrid vehicle drive apparatus A drive apparatus of a hybrid vehicle including an internal combustion engine, a first motor-generator, a power division mechanism, a second motor-generator and a mode switching unit. The mode switching unit includes a hydraulic pressure source, a planetary gear mechanism, a clutch actuator, a brake actuator, a parking lock actuator, control valves, a failure detecting part and an electronic control unit, A microprocessor of the electronic control unit is configured to perform controlling the control valves so that hydraulic oil is supplied to the clutch actuator, the brake actuator and the parking lock actuator, respectively, when a parking brake is operated in a state that the failure of the third control valve is detected by the failure detecting part.
US11066064B2	Systems and methods for operating a hybrid vehicle with a manual shift transmission Systems and methods for operating a vehicle that includes a manual transmission are presented. In one example, a speed rate of change of a driveline torque source is adjusted during a shifting of gears of the manual transmission responsive to a gear that is being disengaged and a gear that is being engaged during the shifting of gears. The torque source may be an electric machine and/or an internal combustion engine.
US11066063B2	Method for controlling torque of diesel hybrid vehicle A method can be used for controlling torque of a diesel hybrid vehicle. The method includes calculating energy consumptions of an engine for respective engine torques within an engine torque range and calculating energy consumptions of a battery for respective motor torques within a motor torque range. A plurality of total energy consumptions can be calculated based on the energy consumptions of the engine and the energy consumptions of the battery. The torque of the diesel hybrid vehicle can be controlled based on an engine torque and a motor torque that are relevant to the minimum of the plurality of total energy consumptions. The energy consumptions of the engine are calculated based on a lower heating value of fuel, fuel consumption rates, and nitrogen oxide (NOx) emissions.
US11066062B2	Systems and methods for reducing engine compression torque Methods and systems are provided for reducing engine compression torque when an engine having a split exhaust system is spun unfueled. In one example, a method may include maintaining closed a blowdown exhaust valve of a cylinder, the blowdown exhaust valve coupled to a first exhaust manifold that directs gases from the cylinder to a catalyst, and opening a scavenge exhaust valve of the cylinder, the scavenge exhaust valve coupled to a second exhaust manifold that directs gases from the cylinder to an exhaust gas recirculation system. In this way, compression of gases within they cylinder is reduced while gas flow to the catalyst is prevented.
US11066057B2	Method for operating a motor vehicle hydraulic brake system A method for operating a hydraulic brake system of a motor vehicle having a brake booster and a hydraulic brake boost wherein a brake pressure is detected and an underpressure, prevailing in an underpressure chamber of the brake booster is estimated on the basis of the detected brake pressure. The hydraulic brake boost controlled based on the estimated underpressure, with the estimated underpressure taking into account an actuation of the hydraulic brake boost.
US11066053B2	Brake pedal weight device and related methods The present invention provides methods and apparatus for engaging the brake pedal of a vehicle using only the weight of the device, allowing a single person to check for proper functioning of the vehicle's brake lights without having to further attach the device to a seat or steering wheel of the vehicle, and methods of using the same. The device may include an elongated arm or lever, an attachment member at one end of the arm for engaging it with the brake pedal, and a weighted member at the opposite end of the arm for providing downward force against the brake pedal. The attachment member may comprise a bracket with one or more widths, allowing the device to securely engage with brake pedals of varying sizes and thicknesses, such that the same bracket may be used to engage a relatively small and thin brake pedal of a car, or a larger, thicker brake pedal of a commercial vehicle such as a bus or a semi-truck.
US11066049B2	Chamois drying device An improved chamois drying device includes a malleable chamois body having a pocket that is interposed between a front surface, a rear surface, a pair of opposing side edges, a bottom edge and a top edge. An absorbent sponge is positioned within the pocket of the chamois body and functions to remove water accumulated by the chamois body. The chamois body is constructed from one or more pieces of water repellant chamois and includes an opening that is in communication with the pocket for receiving and positioning the absorbent sponge. One or more connectors are positioned along either side of the opening to secure the opening into an open or a closed position.
US11066044B2	Key-shape data management system and key-shape data management method A key-shape data management system includes a storage server, an acceptance server, and a transmission server. The storage server stores vehicle identification information capable of identifying a vehicle, mechanical lock identification information capable of identifying a mechanical lock mounted on the vehicle, key-shape data of a mechanical key used in combination with the mechanical lock, and information on multiple manufacturing bases capable of manufacturing the mechanical key. The acceptance server accepts a request for acquiring the mechanical key together with determining information and delivery location information indicating a delivery location of the mechanical key. The transmission server determines the vehicle identification information based on the determining information, determines the key-shape data based on the vehicle identification information, determines one of the manufacturing bases corresponding to the delivery location, and transmits the delivery location information and the key-shape data to the determined manufacturing base.
US11066043B2	Vehicle and method of controlling the same Provided is a vehicle including: a communication unit configured to communicate with a user terminal; and a control unit configured to, upon receiving a response signal including terminal information of the user terminal from the user terminal, determine an authentication allowed time for authenticating the user terminal on the basis of the terminal information, generate user information including the terminal information and the authentication allowed time corresponding to the terminal information, and authenticate the user terminal on the basis of the generated user information.
US11066042B2	Webbing take-up device A webbing take-up device is provided with a spool, a first rotor and a second rotor. A webbing to be applied to a vehicle occupant is taken up onto the spool by the spool rotating in a take-up direction. The first rotor is provided to be rotatable together with the spool, includes first engaging teeth with which a moving member that is moved engages, and is rotated when the moving member that is moved engages with the first engaging teeth. The second rotor is provided to be rotatable together with the spool, includes second engaging teeth with which the moving member that is moved engages, and is rotated when the moving member that is moved engages with the second engaging teeth. The second engaging teeth are disposed so as to overlap with the first engaging teeth in a rotation circumference direction of the first rotor.
US11066036B2	Far side airbag apparatus for vehicle A far side airbag apparatus for a vehicle for installation at a side of a frame of a backrest of a seat directed toward an inner center portion of the vehicle such that the far side airbag is expanded and deployed between at least two backrests arranged widthwise along the vehicle. The far side airbag includes an inner part directed toward an occupant seated in a direction opposite to a collision side of the vehicle upon vehicle collision and an outer part directed toward the inner center portion of the vehicle upon vehicle collision. When a vehicle collision occurs, for example, when a side inclination collision of the vehicle occurs, the occupant seated in opposition to the collision side of the vehicle may be prevented from abruptly moving toward the front portion and the inner center portion of the vehicle out of the protection range of the far side airbag. Thus, collision between occupants seated on a driver seat and an occupant seat can be effectively prevented.
US11066035B2	Airbag module and method for mounting an airbag module An airbag module (10) comprises a housing (12), a folded airbag (16) and a flexible fixation (14) which fixes the folded airbag (16) on the housing (12). There is provided a tensioning device (24) by which the fixation (14) can be brought from an initial state to a tensioned state. Moreover, a method of mounting an airbag module (10) is provided.
US11066032B2	Dash mounted airbag An assembly includes a dash and an airbag supported by the dash. The airbag is inflatable to an inflated position. The airbag in the inflated position has a first end and a second end spaced from each other in a cross-vehicle axis and an inflation chamber between the first end and the second end. The airbag includes a tube extending through the inflation chamber from the first end to the second end.
US11066028B2	Side barrier and hinge A side barrier for a truck or trailer, the side barrier comprising at least one barrier member and at least two support arms between which the at least one barrier member hingedly extends, the at least two support arms being provided with hinges one for connection to the at least one barrier member and the other for connecting the side barrier to the vehicle in a position lying parallel to the longitudinal length of the vehicle, wherein all the said hinges are arranged with respectively parallel axes. Usually a second barrier member is present via which the other hinges connect the support arms to the truck or trailer. The side barrier is for lowering the window below pre-existing side barriers for preventing or reducing accidents involving vulnerable people such as pedestrians or cyclists and vehicles.
US11066027B2	In-vehicle power supply apparatus configured to charge a plurality of batteries An in-vehicle power supply apparatus includes a converter that outputs DC power. A first power storage device and a second power storage device are charged via the converter. A first switch selects on/off between the converter and the first power storage device. A second switch selects on/off between the converter and the second power storage device. A voltage monitoring circuit detects a DC voltage on the output side of the converter, at a point closer to the converter than are the first switch and the second switch.
US11066025B2	Electric vehicle drive system and operation method of the same An electric vehicle drive system includes a controller area network (CAN) bus, a plurality of sensors, a vehicle functional module, a database device, an artificial intelligence (AI) computer and an intermediate agent device electrically connected to the database device, the vehicle functional module and the AI computer, and used to identify the kind of the vehicle functional module, match out a communication format corresponding to the kind of the vehicle functional module, produce an instruction complying with the communication format by simulating another instruction received from the AI computer, and send the instruction to the vehicle functional module for performing a specific function for a vehicle.
US11066020B2	Vehicle body structure A vehicle body structure that includes a storage structure, at least one fixed cover and at least on sliding cover. The storage structure defines at least one opening and at least one storage space, the at least one opening exposing the at least one storage space. The fixed cover is non-movably fitted to the storage structure covering a first portion of the opening. The sliding cover is installed to the storage structure for sliding movement along the opening such that in a closed orientation, the sliding cover covers a second portion of storage space such that the fixed cover and the sliding cover completely conceal the storage space, and, in an open orientation the sliding cover exposes the second portion of the storage space. The storage structure is dimensioned and contoured to removably install to a rear interior cargo area of a passenger vehicle.
US11066018B1	Customizable vehicle side mirror trim A customizable vehicle side mirror trim as provides a subtle yet distinctive trim accent to create a clean, custom appearance for any vehicle make or model, without covering the entire mirror housing. The customizable vehicle side mirror trim can be quickly installed to add a flash of color or a touch of polished texture to the user's side mirrors, for a strong, stylish look that will set the vehicle apart. The customizable vehicle side mirror trim easily clips onto the edge of the mirror housing and attaches securely with adhesive foam. This way the customizable vehicle side mirror trim will not obstruct the side mirror's movements.
US11066017B1	Geometrically shaped ellipsoid vehicular mirror Cross-view mirrors for buses and other vehicles which provide modified image sizes. The mirror assemblies have lens members created from the shape of a portion of an elliptical or circular toroid volumetric shape with an elliptical or circular cross-sectional shape. A first embodiment has an elliptical toroid volumetric shape with an elliptical cross-sectional shape. A second embodiment has an elliptical toroid volumetric shape with a circular cross-sectional shape. A third embodiment has a circular toroid volumetric shape with an elliptical cross-sectional shape.
US11066014B1	360 degree trailer camera view system Systems and methods for receiving a video feed from a trailer control module disposed in a vehicle trailer are described. One method includes aggregating a trailer front view, a trailer rear view, a trailer left view, and a trailer right view into an aggregated birds-eye view at a first control module disposed on the trailer, and sending the aggregated view to a vehicle towing the trailer via a single auxiliary video channel integrated into a trailer hitch wiring harness. The method further includes receiving the feed of the birds-eye view at the second control module disposed in the vehicle via the single auxiliary camera input channel, and displaying the trailer birds-eye view video feed at an output display disposed in a cabin of the towing vehicle. The birds-eye view may be output on a split screen in conjunction with a rear-view of the trailer, obtained from a vehicle camera system.
US11066013B2	Viewing device for vehicle A viewing device for a vehicle has: a monitor that displays a captured image of a vehicle rear side; and a control device that carries out display control that compresses the captured image such that a compression rate gradually becomes higher from a vehicle inner side toward outer sides, and displays an image on the monitor.
US11066007B1	Intelligent car lamplight control device The disclosure discloses an intelligent car lamplight control device, including an ambient light intensity sensor, a speed sensor, a microprocessor control unit (MCU), a wireless transmitter, and a main lamplight control system. The ambient light intensity sensor is configured to automatically monitor a light intensity outside a car; the speed sensor is configured to detect a driving speed of the car; the MCU is configured to acquire a light intensity signal transmitted from the ambient light intensity sensor and a speed signal transmitted from the speed sensor; the wireless transmitter is configured to wirelessly transmit a control command transmitted from the MCU to the main lamplight control system; and the main lamplight control system is configured to receive the control command transmitted from the wireless transmitter and correspondingly control lamplight according to the control command.
US11066001B2	Construction barrier moving device and method An device for moving a construction barrier includes a connection member, an alignment member, and an engagement member. The connection member is configured to removably attach the device to a vehicle. The alignment member is configured to attach to the connection member and to the engagement member, and the engagement member extends at an angle away from the vehicle. When the device is attached to the vehicle and engages a construction barrier, the engagement member is configured to move the construction barrier behind the vehicle and toward a path of travel of the vehicle.
US11066000B2	Systems, methods, and apparatuses for engaging and transporting objects Systems, methods, and apparatuses for engaging, lifting, and moving objects such as wheeled cargo trailers are provided. In one embodiment, a mobile apparatus includes a transport mechanism, a frame, and one or more lift assemblies. The lift assemblies may be adjusted using one or more attached actuators that position the lift assemblies and/or components thereof for engaging and lifting an object. The transport mechanism may be autonomously operated. A vision system may be used to locate and identify objects and/or guide the mobile apparatus into position to engage and lift the objects. An adapter for a pneumatic braking system of a wheeled cargo trailer is also provided. The adapter provides a pneumatic attachment for a pressurized air source that is separate from a glad hands connector attached to the braking system.
US11065999B2	Liftgate alert apparatus A liftgate alert apparatus for alerting drivers when a liftgate is down before driving includes a pressure switch configured to be coupled to an air line of an airbrake system of a truck or a trailer. The pressure switch is closed when the airbrake system is activated. A roller switch is in operational communication with the pressure switch and is configured to be coupled to a liftgate. The roller switch is closed when the liftgate is in a down position. An alarm is in operational communication with the pressure switch, the roller switch, and a power source. The alarm has an alarm ground wire. The alarm is configured to be coupled within a cab of the truck or on a front end of the trailer and activates an audio and or visual alert when both the pressure switch and the roller switch are closed.
US11065996B2	Vehicle seat A vehicle seat includes a seat cushion, an ottoman, a driving unit, and a power transmission mechanism. An ottoman frame formed as a framework of the ottoman is pivotably attached to a cushion frame formed as a framework of the seat cushion. The driving unit has an output shaft capable of outputting a rotational driving force, and the ottoman frame has a pantograph mechanism that allows the ottoman to deform between an extended state and an unextended state. The power transmission mechanism has a pinion gear fixed to the output shaft, and a first sector gear meshing with the pinion gear. The first sector gear is connected to a driving link of the pantograph mechanism, to implement pivoting and deformation of the ottoman.
US11065991B2	Insert for integration into trim layer and providing conditioning An insert comprising: (a) a cover layer; (b) a spacer layer located below the cover layer; (c) a connection material that is adapted to extend between and connect the cover layer to a trim layer so that the insert is fixed to the trim layer.
US11065989B2	Scissor lift assembly A vehicle seat includes a seat base operably coupled with a seatback and having a seat pan. An upper connector is positioned on the seat pan. A lift assembly is operably coupled with the seat pan and includes a bracket defining a bracket slot. An outer link has a first end rotatably coupled with the seat pan and a second end that includes a lower connector. The lower connector is slidably received by the bracket slot. An inner link has a first end rotatably coupled with the bracket and a second end that defines a link slot. The link slot is configured to receive the upper connector. A sector gear is configured to facilitate vertical translation of the seat base.
US11065985B2	Vehicle seat device A vehicle seat device includes a seat main body having a seat cushion and a seatback, and a tilt device configured to exert a tilt function to tilt the seatback towards a seat front side. The tilt device includes an electric motor and a spring. The electric motor is configured to exert a rotational force to rotationally displace the seatback. The spring is configured to exert a resilient force to rotationally displace the seatback towards the seat front side.
US11065982B2	Method and system of installation of a plurality of droppers of an overhead contact system section A method including measuring a distance between two successive supporting poles delimiting a section to be realized, inputting data into a computer programmed to output a layout plan indicating a position and a length for each dropper to install, preparing each dropper with a dedicated machine, moving a first platform along the section, which is equipped with a position unit and a marking device to set a mark on the contact wire at each position where a dropper is to installed, moving a second platform along the section, the second platform being loaded with the droppers that have been prepared, and fixing manually each dropper between the messenger wire and the contact wire in registration with a corresponding mark set on the contact wire.
US11065979B1	Aircraft monitoring system and method for electric or hybrid aircrafts This disclosure describes at least embodiments of an aircraft monitoring system for an electric or hybrid airplane. The aircraft monitoring system can be constructed to enable the electric or hybrid aircraft to pass certification requirements relating to a safety risk analysis. The aircraft monitoring system can have different subsystems for monitoring and alerting of failures of a component, such as a battery pack, a motor controller, and/or a motors. The failures that pose a greater safety risk may be monitored and indicated by one or more subsystems without use of programmable components.
US11065978B2	Systems, methods, and storage media for adapting machine learning models for optimizing performance of a battery pack Systems, methods, and storage media for optimizing performance of a vehicle battery pack are disclosed. A method includes receiving data pertaining to cells within a battery pack installed in each vehicle of a fleet of vehicles, the data received from at least one of each vehicle, providing the data to a machine learning server, and directing the machine learning server to generate a predictive model. The predictive model is based on machine learning of the data. The method further includes providing the predictive model to each vehicle, the predictive model providing instructions for adjusting configuration parameters for each of the cells in the battery pack such that the battery pack is optimized for a particular use, and directing each vehicle to optimize performance of the vehicle battery pack based on the predictive model.
US11065976B2	Docking and recharging station for unmanned aerial vehicles capable of ground movement The techniques introduced here include a system to perform an efficient docking and recharging of unmanned aerial vehicles capable of ground movement, which makes use of a platform, a ramp, a circuitry and an interface integrated in the platform that are capable of recharging said vehicles, and through which it is possible to shield from adverse weather conditions and to recharge multiple unmanned aerial vehicles capable of ground movement at the same time, without incurring in unwanted disturbances and delays.
US11065965B2	Method and system for configuring regenerative braking energy recovery devices in urban rail transit A method and system for configuring regenerative braking energy recovery devices in urban rail transit provided by the present application, successively including the following steps: calculating a preliminarily configured capacity Pn of a regenerative braking energy recovery device predetermined for the traction substation n, then obtaining an optimally configured capacity Qn of the regenerative braking energy recovery devices; further, configuring the total number of the regenerative braking energy recovery devices; finally, configuring the type of the regenerative braking energy recovery devices. By reasonably configure the capacity and number of regenerative braking energy recovery devices in traction substations, the configuring method of the present application allows the regenerative braking energy generated by a train during braking to be completely absorbed, thus reduce the energy consumption of braking resistors. Meanwhile, the waste of idle regenerative braking energy recovery devices is avoided, and the acquisition cost of devices is reduced. By reasonably configuring the type of regenerative braking energy recovery devices, the deficiencies of a single regenerative braking energy recovery device can be avoided.
US11065964B2	Method for operating a motor vehicle A method for operating a motor vehicle, including an electric machine and a coupling device, which, in a first coupling state, couples the electric machine to a drivetrain and, in a second coupling state, decouples the electric machine from the drivetrain, wherein the method includes the following steps: a) registering an item of coupling information, which specifies whether the coupling device is in the first or second coupling state, b) analyzing a recuperation condition, the fulfillment of which is dependent on the coupling information, wherein the recuperation condition is fulfilled or can only be fulfilled if the coupling device is in the second coupling state, and c) braking the electric machine by operating the electric machine as a generator if the recuperation condition is fulfilled.
US11065963B2	Diagnostic system for a DC-DC voltage converter A diagnostic system for a DC-DC voltage converter includes a microcontroller having a first diagnostic handler application and first and second applications. The first application sets a first non-recoverable diagnostic flag associated with the DC-DC voltage converter to a first encoded value having each nibble thereof selected from an odd Karnaugh set of binary values. The second application sets a second non-recoverable diagnostic flag to a second encoded value having each nibble thereof selected from an even Karnaugh set of binary values. The first diagnostic handler application sets a first master non-recoverable diagnostic flag to a first encoded fault value if the first non-recoverable diagnostic flag is equal to a second encoded fault value, or the second non-recoverable diagnostic flag is equal to a third encoded fault value.
US11065960B2	Curved vehicle displays Embodiments of a curved vehicle display including a display module having a display surface, a curved glass substrate disposed on the display surface having a first major surface, a second major surface having a second surface area, and a thickness in a range from 0.05 mm to 2 mm, wherein the second major surface comprises a first radius of curvature of 200 mm or greater, wherein, when the display module emits a light, the light transmitted through the glass substrate has a substantially uniform color along 75% or more of the second surface area, when viewed at a viewing angle at a distance of 0.5 meters from the second surface. Methods of forming a curved vehicle display are also disclosed.
US11065959B2	Condition-based determination and indication of remaining energy range for vehicles Systems and methods for determining and indicating an energy range of a host vehicle. A sensor can be positioned to acquire data corresponding to an amount of energy stored in an energy storage system of the host vehicle. An anticipated operating condition for a forthcoming location of the host vehicle can be determined based on at least one operating condition provided from at least one of a plurality of vehicles that 1) has a vehicle type that is the same as a vehicle type of the host vehicle and 2) is located at a respective location that is proximate to the forthcoming location of the host vehicle. The remaining energy range can be determined based on 1) the amount of energy stored in the energy storage system and 2) the anticipated operating condition, and an output system of the host vehicle can indicate the remaining energy range for the host vehicle.
US11065954B2	Fuel fill opening structure for fuel tank A fuel fill opening structure for a fuel tank includes a fuel filler pipe, a fuel fill opening, and a flow guide. The flow guide includes a main guide wall which partitions a fuel introduction region inside the fuel filler pipe into an upper space communicating with a tank main body side and a lower space communicating with the fuel fill opening side, and a partition wall provided to be continuous with the main guide wall and configured to close a space between an upper surface side of the main guide wall and an inner surface of the fuel filler pipe. The main guide wall includes a bent inclined part that is bent and inclined downward from a middle portion in running from the fuel fill opening side toward the tank main body side. The bent inclined part has a shape in which a width thereof becomes smaller when viewed from above as it inclines downward.
US11065953B1	Method and system for forming a self-sealing volume using a breather system A fabric and elastomeric material (referred to as a fabric trilayer) combined with a sealant may be applied in such a fashion so as to eliminate or minimize air entrapment in an elastomeric composite structure that forms a seal-sealing volume. The performance of the self-sealing volume is dramatically improved with this minimizing of air entrapment. Surprisingly and unexpectedly, this construction approach may be accomplished without significantly adding to the weight or thickness of the volume and without affecting the outer dimension of the self-sealing volume. Thus, a method and system for forming a self-sealing volume are described. The system includes an elastomeric composite structure comprising at least one layer of an elastomeric material derived from a neat (no solvent) elastomeric material that does not substantially react at room temperature.
US11065948B2	Vehicle powertrain A vehicle powertrain includes a first electric machine and a second electric machine, a transmission arranged to transmit torque from the electric machines to a pair of driven wheels of a vehicle, where the first electric machine is drivingly connected to a first input shaft of the transmission and a second electric machine is drivingly connected to a second input shaft of the transmission, a first torque path for transmitting torque includes only one gear ratio between the first input shaft and an output shaft of the transmission, and a second torque path for transmitting torque includes two selectable and separately engageable gear ratios between the second input shaft and the output shaft of the transmission, and where the three gear ratios of the first and second torque paths are different from each other.
US11065947B2	Apparatus and method for tracking location of sunroof blind An apparatus for tracking the location of a sunroof blind includes: a motor connected to the sunroof blind by a cable; and a controller for determining whether or not a wake-up is performed according to an electromotive force of the motor, and for correcting location information of the sunroof blind according to a determination result.
US11065946B2	Utility vehicle half door A utility vehicle half door includes a unitary molded plastic body that is symmetrical and identical on both a first surface and second surface. Hinge knuckles are integral with the unitary molded plastic body for hinged mounting to the left or right side of a utility vehicle. An interior panel subassembly with the door release handle and door latch may be attached to one of the first and second surfaces.
US11065945B2	Vehicle door structure A vehicle door structure includes an inner panel, an outer panel, a guard beam and a reinforcing member. The guard beam extends laterally in a cavity between the inner and outer panels. The reinforcing member disposed in the cavity and being positioned on a floor of the vehicle door structure below the guard beam.
US11065944B2	Door for vehicle A door of a vehicle may include a first door module forming a door skeleton; a second door module coupled with the first door module and forming a door window; and a door frame coupled to the first door module and engaged with the second door module; wherein the second door module may include a relatively lightweight material as compared to the first door module, reducing weight and cost of the door for the vehicle.
US11065943B2	Vehicle windshield and vehicle component using same Provided are a vehicle windshield equipped with a transparent film at a visual field area, where a negative effect on a driving visibility due to a boundary line between a forming area and a non-forming area of the transparent film is improved, and a vehicle component having the vehicle windshield. The vehicle windshield includes: a window plate; and a transparent film provided at a surface on a vehicle-interior side of the window plate, wherein the vehicle windshield includes a first area where the transparent film is not provided and a second area where the transparent film is provided, at a central area when viewed from a front side, and a boundary between the first area and the second area has no perspective distortion and is constituted by a boundary line having line width visually recognized by scattering of irradiated light of 10 μm to 200 μm.
US11065942B2	Environmental air cleaning device, road vehicle having environmental air cleaning device, and filter element An environmental air cleaning device for a road vehicle removes dust, particulate matter, and/or gases from environmental air. The environmental air cleaning device has one or more filter elements. The environmental air cleaning device is provided with a mounting device that rigidly couples to a vehicle-side mounting device for roof loads. A road vehicle with such an environmental air cleaning device is provided.
US11065939B2	Motor-driven air vent device for vehicle A motor-driven air vent device for a vehicle is provided. The motor-driven air vent device connects a horizontal wing of an air vent to an output shaft of a driving motor through a link structure and rotatably operates the driving motor in the forward direction or the reverse direction by a touch type switch operation. Accordingly, the vertical angular rotation operation for the horizontal wing is automatically performed by the operation of the link structure delivering the torque of the driving motor.
US11065935B2	Thermal management system for electric vehicle An electric vehicle thermal management system is provided. The system includes an inside AC unit having an air inlet unit and an air outlet unit and a cooling core embedded therein. A heating core is disposed between the air outlet unit of the inside AC unit and the cooling core and a control door is disposed inside the inside AC unit to adjust air supply to the heating core. A first flow path circulates to pass through the heating core and includes an electric heater. A branch flow path is branched from downstream point of the heating core of the first flow path and passing through a high voltage battery heat exchange unit. A control valve is disposed in a branch point between the first flow path and the branch flow path and a second flow path circulates between a compressor and a condenser and the cooling core.
US11065934B2	Heat pump system for vehicle with battery and electronic component cooling A heat pump system for a vehicle is provided. The system includes a battery coolant line connected to a battery module. A cooling device selectively connected to the battery coolant line includes a radiator and a first water pump, to circulate a coolant therein. A first chiller is disposed in the battery coolant line and connected to a refrigerant line of an air conditioner to adjust a temperature of a coolant. A second chiller is selectively connected to the coolant line and selectively connected to the refrigerant line to increase a temperature of a coolant by selectively exchanging heat between the coolant and a refrigerant flowing into the second chiller. An integrated control valve is connected to the refrigerant line, the first connecting line, and the second connecting line to adjust a refrigerant flow direction and to selectively expand a refrigerant passing through the integrated control valve.
US11065928B2	Amphibian An amphibious motorcycle with a hull that provides desirable buoyancy for the vehicle to float while in the water and yet allows the vehicle to lean/turn during use on land is provided. The amphibious motorcycle has a front wheel with a front suspension system and a rear wheel with a rear suspension system. Also included can be at least one wheel retraction system that is operable to move the front wheel and/or the rear wheel between a deployed position for use of the amphibious motorcycle on land and a retracted position for use of the amphibious motorcycle on or in the water. The amphibious motorcycle also has a hull that can have a center portion with a center bow and two oppositely disposed and spaced apart side portions each with a side bow.
US11065927B2	Power train for an amphibian A power train for an amphibian operable in land and marine modes includes a prime mover, at least a first land propulsion unit, a first marine propulsion unit, a second marine propulsion unit, and at least one speed change transmission. The prime mover is arranged to drive the at least first land propulsion unit through/via the at least one speed change transmission in land mode, and the prime mover is arranged to drive the first marine propulsion unit and the second marine propulsion unit through/via the at least one, or another, or combinations of, speed change transmission in marine mode. In addition, the present invention provides an amphibian comprising the power train.
US11065925B2	Valve stem apparatus, assemblies and methods for use The present invention provides a tire valve stem assembly for a pneumatic tire having a valve stem for inflating the tire and having a member extending from the valve stem into an interior of the tire to prevent clogging or minimize clogging of the valve stem by leak sealing material.
US11065920B2	Tire-mounted sensor, diagnosis history memory device and diagnosis notification device A condition in which an abnormality can occur in a tire is accurately detected on the basis of a detection signal from an acceleration sensor used to detect a road surface state and a possibility that an abnormality has occurred in the tire is also detected. In addition, the detection result is stored as a diagnosis history. The diagnosis history or the possibility that an abnormality has occurred in the tire are notified through a notification device in a vehicle body side system so that a user is informed in advance of the possibility that an abnormality has occurred in the tire. In addition, when the diagnosis history is checked through a tool in a car repair shop, etc., the diagnosis history stored in a tire-mounted sensor is read out. Accordingly, the possibility of abnormality of the tire can be informed also in the car repair shop, etc.
US11065919B1	Sealing device for tubeless tires A sealing device comprising a flexible holding strip having an adhesive layer on a first surface, wherein the strip is configured for attachment to an inner surface of a tubeless tire via the adhesive layer, and a plurality of flexible flags attached to a second surface of the flexible holding strip opposite the first surface, wherein the plurality of flags is attached to the second surface at a fixed widthwise edge of each of the plurality of flags and wherein the plurality of flags are configured to seal a hole in the tubeless tire when the strip is attached to the inner surface of the tubeless tire is provided. Methods of protecting tires by attaching a sealing device are also described.
US11065915B2	Pneumatic tire A pneumatic tire includes cross belts and one or more protective belts provided in the tire radial direction. A width of a widest protective belt is greater than a width of any of the cross belts. In the tire profile, a maximum projection position of the widest protective belt is A, an end position of the widest protective belt is B, a position at which a straight line a passing through position A extending in the direction normal to a tread surface intersects with the tread surface is A′, and a position at which a straight line b passing through position B extending in the direction normal to the tread surface intersects with the tread surface is B′. An angle formed between a first straight line that links position A and position B and a second straight line that links position A′ and position B′ is from 0° to 15°.
US11065906B2	Assemblies and processes for producing optical effect layers comprising oriented non-spherical oblate magnetic or magnetizable pigment particles The present invention relates to the field of optical effect layers (OEL) comprising magnetically oriented non-spherical oblate magnetic or magnetizable pigment particles on a substrate, spinneable magnetic assemblies and processes for producing said optical effect layers (OEL). In particular, the present invention relates to spinneable magnetic assemblies and processes for producing said OELs as anti-counterfeit means on security documents or security articles or for decorative purposes.
US11065905B2	Method for the insertion of guilloche patterns, method for the extraction of guilloche patterns, method for the authentication of these guilloche patterns and devices for implementation A method of inserting guilloche patterns in a document, each guilloche pattern being capable of encoding variable alphanumeric data ensuring a different aspect at each guilloche pattern so as to render said document secure using an operation of determining an insertion intensity of each guilloche pattern previously generated on the basis of a mid-gray level of the document near said guilloche pattern. A device for implementing this insertion method. The method further provides for extracting guilloche patterns from a secure document likely to be degraded by determining a contrast card of at least one portion of the secure document that includes the guilloche patterns, identifying, on this contrast card an optimal percolation trajectory, and extracting the optimal percolation trajectory, said trajectory corresponding to the guilloche pattern. The method further provides for authentication of the guilloche patterns of a secure document likely to be degraded, by the extraction operations, and comparing each extracted guilloche pattern with a corresponding theoretical guilloche pattern.
US11065903B2	Gravure printing plate, gravure printing method, and manufacturing method for electronic component A gravure printing plate includes a cylindrical or substantially cylindrical gravure roller with a peripheral surface. Plural cells corresponding to a pattern to be printed are disposed on the peripheral surface of the gravure roller. First and second regions are provided on the peripheral surface of the gravure roller. The pattern to be printed includes at least two patterns. Plural cells corresponding to one of the two patterns are disposed in the first region. Plural cells corresponding to the other one of the two patterns are disposed in the second region.
US11065902B2	Recording medium According to an example, a recording medium may include a substrate; a first coating including an inorganic pigment, a first binder, and a fixative agent; and a second coating including inorganic nanoparticles and a second binder; in which the inorganic pigment may be a plate-shaped pigment.
US11065901B2	Transfer method A transfer method is provided and includes a disposing step of disposing a transfer sheet and a medium in an inside of a sealed space formed by using a pressure welding sheet having flexibility in at least one part; a pressure welding step of suctioning the inside of the sealed space by a negative pressure and pressure welding the pressure welding sheet and the medium by the negative pressure to closely attach the transfer sheet and the medium; an irradiating step of softening an adhesive layer of the transfer sheet by irradiation of a light ray in a state in which the transfer sheet is closely attached to the medium by the pressure welding sheet and adhering the adhesive layer to the medium by a pressure welding force from the pressure welding sheet; and a peeling step of peeling off the transfer sheet from the medium after the irradiating step.
US11065897B2	Information processing apparatus generating display screen data based on information on residual quantity of printing agent In an information processing apparatus, a processor acquires first and second information on residual quantities of printing agent stored in first and second cartridges respectively. The first cartridge is mounted on a portion including a tank. The processor generates display screen data including first and second objects. The first object has a first position corresponding to a minimum residual quantity of the printing agent in a first state where the printing agent remains in the first cartridge. The second object has a second position corresponding to a maximum residual quantity of the printing agent, and a third position corresponding to a minimum residual quantity of the printing agent in a second state where the printing agent does not remain in the first cartridge but remains in the tank. The first position and one of the second and third positions are aligned at a reference position.
US11065896B2	Arrangement with a receipt printer arranged in a housing An arrangement includes a receipt printer for printing a receipt arranged in a housing. The housing includes a pivoting lid which in an open state allows access to the receipt printer and in a closed state prevents access to the receipt printer. The lid has an opening through which a receipt printed by the receipt printer can be output in the closed state. The arrangement has a receipt output unit which in the closed state is arranged in the opening of the lid opposite to the receipt printer, at least a first receipt guiding unit and at least a first elastically deformable element for spring-mounting at least one component of the first receipt guiding unit. The receipt printer has a second receipt guiding unit. The first receipt guiding unit is engaged with the second receipt guiding unit when the lid is moved from the open state into the closed state.
US11065891B2	Image recording device An image reading device includes a tray unit, a recording unit disposed above the tray unit, an outer guide defining a curved path extending from the tray unit to the recording unit, a sheet feeder configured to feed a sheet from the tray unit to the curved path, and a return guide disposed between the recording unit and the tray unit. The return guide pivots about a shaft and guides the sheet having an image recorded thereon back to the curved path. The tray unit includes at least one supporting portion. The return guide includes at least one supported portion. The at least one supporting portion of the tray unit engages the at least one supported portion of the return guide such that the return guide takes a guiding position in which the return guide defines a return path extending to the curved path.
US11065886B2	Printer A printer includes a print head that performs printing on a recording medium, a frame, a platen roller attached to the frame, a head spring that biases the print head toward the platen roller, a hook provided on a facing surface of the frame facing a back surface of the print head, and a support provided at an end of the head spring and attached to the hook. The head spring is rotatable about the support.
US11065885B2	Recording method, ink set, and printing apparatus Provided is a recording method including: a first applying step of applying anionic first processing liquid on a medium; a second applying step of applying cationic second processing liquid on the medium, causing the first processing liquid and the second processing liquid to react with each other, and generating mixed liquid, subsequently to the first applying step; and a first drying step of drying the mixed liquid subsequently to the second applying step, in which the mixed liquid is cationic.
US11065882B2	Image-recording device having first sensor for detecting liquid in cartridge and second sensor for detecting liquid in tank In an image-recording device, a cartridge has a first chamber, a first outlet, and a first sensor. A mount body includes a tank in connection with the cartridge, and a second sensor. The tank has an inlet, and a second chamber. The liquid in the first chamber is capable of flowing into the second chamber via the first outlet of the cartridge and the inlet of the tank. The first sensor outputs a first signal when a level of the liquid in the second chamber is higher than a first position, and outputs a second signal when the level is lower than the first position. The second sensor outputs a third signal when the level is higher than a second position, and outputs the fourth signal when the level is lower than the second position.
US11065880B2	Liquid cartridge provided with liquid supply portion having guide groove A liquid cartridge configured to be inserted into a cartridge attachment section includes: a cartridge body having a liquid storage chamber, and a liquid supply portion configured to supply the liquid stored in the liquid storage chamber to an outside. The liquid supply portion includes: a front end face facing frontward, an outer peripheral surface extending rearward from the front end face, and at least one guide provided at the outer peripheral surface. Each of the at least one guide is guided by corresponding at least one projection of the cartridge attachment section during attachment of a liquid supply tube of the cartridge attachment section to the liquid supply portion at a time of attachment of the liquid cartridge to the cartridge attachment section. Each of the at least one guide includes: a first guide portion, and a second guide portion.
US11065879B2	Ink refill container and ink refill system An ink refill container 31 includes a container body 61 including an inner tube portion 62 constituting an ink containing chamber 41, an inner bottom 64 joined to the inner tube portion 62, an ink-outlet forming portion 38 that is provided in the inner tube portion 62 and that includes an ink outlet 46, and a cover 75 including an outer bottom 76 covering the inner bottom 64 from below. The cover 75 includes a receiving recess 95 that is configured of the outer bottom 76 and a tubular receiving wall 93 integrally coupled to the outer bottom 76 and that receives an ink IK leaked from the ink containing chamber 41 through a junction of the container body 61 and the inner bottom 64.
US11065874B2	Method of manufacturing a liquid ejection head A method of manufacturing a liquid ejection head including a first step of having a molten resin becoming a first portion flow in between a first position in a first mold and a first position in a second mold and the molten resin becoming a second portion flow in between a second position in the first mold and a second position in the second mold; a second step of relatively moving the first and second molds, after opening the molds; a third step of closing the molds; a fourth step of joining the first and second portions, a fifth step of taking out the first and second portions and the sealing portion from the molds and mounting a recording element substrate; and a step of forming a space portion between a liquid supply path surface and a mounting surface.
US11065873B2	Liquid ejection apparatus A liquid ejection apparatus includes a supply manifold, a return manifold, and a plurality of individual channels. The supply manifold and the return manifold are elongate and vertically overlap each other, and liquid flows therein. Each individual channel connects the supply manifold and the return manifold and includes a supply throttle connected, at a supply-manifold-side opening thereof, to the supply manifold, a return throttle connected, at a return-manifold-side opening thereof, to the return manifold, a nozzle from which liquid is ejected, and a descender connecting the supply throttle and the return throttle, and connected to the nozzle. The supply-manifold-side opening of the supply throttle is positioned to vertically overlap a central area of the supply manifold in a width direction, and the return-manifold-side opening of the return throttle is positioned to vertically overlap a central area of the return manifold in the width direction.
US11065870B2	Liquid ejection head having plurality of sets of rows of pressure chambers, and capable of avoiding mixture of different kinds of liquid A liquid ejection head includes a plurality of sets of a first row, a second row, and a flow path in communication with the first row and the second row. Each of the plurality of sets is provided for each respective one of a plurality of kinds of liquids different from one another. The first row includes a plurality of first pressure chambers. The second row includes a plurality of second pressure chambers. The second row is positioned beside the first row. The flow path is in communication with the plurality of first pressure chambers and the plurality of second pressure chambers. The flow path includes a plurality of first communication passages, a plurality of second communication passages, a plurality of third communication passages, a plurality of fourth communication passages, a first manifold, a second manifold, and a common manifold.
US11065869B2	Liquid discharge control device and liquid discharge apparatus A control device includes circuitry to generate a drive waveform applied to an electromechanical transducer element that changes pressure in a liquid chamber communicating with a nozzle to discharge liquid. The drive waveform includes, in a pulse unit of one discharge cycle, a first discharge pulse waveform including a damping element to damp a vibration of the liquid, and a second discharge pulse waveform subsequent to the first discharge pulse waveform. The circuitry selects at least one of the first and second discharge pulse waveforms in the pulse unit, in accordance with a volume of the liquid to be discharged, to cause the nozzle to discharge different volumes of the liquid. A pulse interval between the first and second discharge pulse waveforms is from Phlm×(N±⅛) to Phlm×(N±¼), where Phlm represents a Helmholtz period of the liquid chamber and N represents an integer of 1 or greater.
US11065866B2	Apparatuses for producing optical effect layers The apparatus and methods of the present disclosure relate to devices comprising spinning magnets driven by electric motors for use with printing or coating equipment. These devices and methods are for orienting magnetic or magnetisable pigment particles in an unhardened coating composition on a substrate. Specifically, these devices and methods are for producing optical effect layers. The apparatus comprises a holder, onto which is mounted a motor and a permanent magnet assembly. The motor is configured to spin the permanent magnet assembly. The holder is configured to be removably fixed to a base of a rotating magnetic cylinder (RMC) or a flatbed printing unit.
US11065864B2	Hybrid polymeric structure, a method for fabricating a hybrid polymeric structure and a method for connecting two polymeric layers with the hybrid polymeric structure A hybrid polymeric structure, a method for fabricating a hybrid polymeric structure and a method for connecting two polymeric layers with the hybrid polymeric structure, the hybrid polymeric structure including a first polymeric material arranged in a first three-dimensional network, wherein the first three-dimensional network defines a cavity with a plurality of interconnected portions within the first three-dimensional network; and a second polymeric material substantially occupies the cavity of the first three-dimensional network, and defines a second three-dimensional network; wherein the first three-dimensional network and the second three-dimensional network are arranged to physically engage with each other so as to form a unified structure combining the first polymeric material and the second polymeric material.
US11065861B2	Methods for composite filament threading in three dimensional printing Various embodiments related to three dimensional printers, and reinforced filaments, and their methods of use are described. In one embodiment, a void free reinforced filament is fed into an conduit nozzle. The reinforced filament includes a core, which may be continuous or semi-continuous, and a matrix material surrounding the core. The reinforced filament is heated to a temperature greater than a melting temperature of the matrix material and less than a melting temperature of the core prior to applying the filament from the conduit nozzle.
US11065856B2	Industrial machine for applying temporary or permanent protective films to planar surfaces acting simultaneously on two faces, having a system for cutting the film and positioning edge-to-edge or with a margin, automatically adapting to suit changes in the parts that are to be treated, using an electrostatic method The invention relates to an industrial machine for vertically applying temporary or permanent protective films on plane surfaces and having an automatic system for cutting the film, positioning it edge-to-edge or with a margin (in particular in the context of film-coating sheets of glass for the purposes of glazing any window frames without damaging the temporary protection; the glass being film-coated while leaving a setback) by acting simultaneously on both faces and adapting automatically to changes in the format of the parts for treatment, using an electrostatic method for holding the film in position on the applicator roller.
US11065853B2	Polyimide film layered body A laminate mainly made of polyimide with low thermal expansion, high mechanical strength, and high heat resistance, and a method for manufacturing the same are provided. A surface of a polyimide film is activated and then treated by a silane coupling agent. Subsequently, the obtained silane coupling agent-treated polyimide films are superimposed, and pressure and heat are applied to the superimposed polyimide films so as to manufacture a polyimide film laminate. The obtained polyimide film laminate has a cross-sectional structure of superimposing polyimide film layers and silane coupling agent condensate layer(s) alternately to each other. Adhesive strength between the polyimide films of the polyimide film laminate of the present invention does not change largely from initial adhesive strength even after heat treatment at 400° C. for 15 minutes. Further, the polyimide film laminate exhibits a high bending elastic modulus and impact resistance.
US11065847B2	Method for the production of multilayer laminated board and resulting board The method is carried out by means of the stacked deposition of a series of layers of fibers and/or particles with a binder material and/or other chemical additives on a conveyor belt until a multilayer mat is produced, in which the layers are physically different from one another. The method comprises: defining the final thickness and density of the board; defining the number of layers forming the board and the type of material to be used for each layer; selecting and preparing the constituent material of each layer to be formed; depositing, in a stacked and staggered manner, the layers previously defined according to weight per m2 of each layer; pre-compacting and, optionally, pre-heating the mat; compacting the mat using pressure and heat. The invention also relates to the board produced using said method for the production of a symmetrical or asymmetrical, stable board.
US11065844B2	Laminated glass A laminated glass according to the present invention includes an outer glass sheet, an inner glass sheet that is arranged opposite to the outer glass sheet and has a smaller thickness than that of the outer glass sheet, and an interlayer sandwiched between the outer glass sheet and the inner glass sheet. A transmittance with respect to light having a wavelength of 850 to 950 nm is 30 to 80%. The outer glass sheet has a thickness of 1.8 to 2.3 mm. The inner glass sheet has a thickness of 0.6 to 2.0 mm. The interlayer includes a plurality of layers including at least a core layer. The core layer has a Young's modulus of 1 to 20 MPa at a frequency of 100 Hz and a temperature of 20° C., the Young's modulus being lower than the Young's modulus of the other layer.
US11065838B2	Shaped object and shaped object manufacturing method A shaped object includes a thermally expandable sheet including (i) a base, (ii) a thermal expansion layer disposed on a first surface of the base and including a thermally expandable material, and (iii) a thermal conversion member disposed on at least one of a second surface of the base or the thermal expansion layer, and including a thermal conversion material for conversion of electromagnetic waves into heat. The thermal conversion member further includes thermal conversion layers disposed on an entire region corresponding to an expansion region for expansion of the thermal expansion layer. At least part of one of the thermal conversion layers is disposed at a location separated from an adjacent other thermal conversion layer. Upon expansion of the thermal expansion layer, (i) the thermal expansion layer partially peels away from the thermal expansion layer in a region where the thermal conversion layer is disposed, and (ii) the thermal expansion layer also expands in a region between the one thermal conversion layer and the other thermal conversion layer.
US11065834B2	Mold for manufacturing a midsole for an article of footwear A method of manufacturing a midsole includes placing first and second preforms into a midsole recess of a mold, with first and second portions of the mold defining a first overflow chamber connected to the first recess; closing the mold by positioning the first and second portions in contact with one another; heating the mold for a predetermined period of time at a predetermined temperature such that the first and second preforms melt and bond together to form a midsole, with a portion of each of the first and second preforms flowing into the first overflow chamber to form a first overflow portion; removing the midsole from the mold; allowing the midsole to expand; and cutting away the first overflow portion.
US11065833B2	Flexible core for machine processing or production of composite parts or materials The invention is directed to a core material, suitable for use in a closed mold system, based on at least one fibrous web containing a foam-structure within the web, said foam-structure being formed of a plurality of members that are separated from each other by channels, wherein said core material has a compression-resistance of greater than 40% at a pressure of 4 bar and at a temperature that is greater than or equal to 80° C.
US11065828B2	Method and system for fabricating a composite structure A method and system for fabricating a composite structure is disclosed. A composite preform (10) has an upper surface (14) and an opposing lower surface (15). The upper and lower surfaces (14, 15) each define a preform major surface. A heat sink (120) is located in proximity to one of the preform major surfaces so as to extend across only a portion (16) of the composite preform (10). A resin is cured in the composite preform (10) to form the composite structure. The resin cures exothermically. During curing of the resin, heat is conducted away from the portion (16) of the composite preform (10) into the heat sink (120).
US11065820B2	Optimization approach to load balancing and minimization of build time in additive manufacturing According to some embodiments, system and methods are provided comprising receiving input including: coordinates of one or more regions to be fabricated on a build plate, a laser boundary for each of two or more lasers, wherein the lasers fabricate the one or more regions, and a processing time for each region; deriving a prioritized sequence of the one or more regions to be fabricated; determining, based on the received coordinates and received laser boundary, one or more potential lasers assignments for each region; determining, based on the determined potential laser assignments, the prioritized sequence of the one or more regions, and the processing time for each region, a laser-to-region sequence for the one or more lasers to fabricate the one or more regions; assigning the determined laser-to-region sequence to the one or more lasers for fabrication of the one or more regions. Numerous other aspects are provided.
US11065817B2	Extrusion orifice cleaning Described is a self-cleaning extrusion orifice assembly including an enclosure, a cylindrical body inserted into the enclosure and terminated by an extrusion orifice. The self-cleaning extrusion orifice assembly is operated by a pressurized air flow. The pressurized air flow flushes surfaces of some elements of self-cleaning extrusion orifice assembly removing debris that could be deposited on these surfaces. In addition, some elements of self-cleaning extrusion orifice assembly are configured to scrape extrusion process debris from the same surfaces.
US11065810B2	Additive manufacturing system and method An additive manufacturing system including a two-dimensional energy patterning system for imaging a powder bed is disclosed. Improved optical systems supporting beam combining, beam steering, and both patterned and unpatterned beam recycling and re-use are described.
US11065807B2	Method of manufacturing a heat-shrink elastomeric element Provided are methods and systems for manufacturing and using heat-shrink elastomeric. An example method of manufacturing a heat-shrink elastomeric element comprises providing a thermoplastic elastomeric element having a first shape; modifying the thermoplastic elastomeric element to produce a thermoset elastomeric element having the first shape; heating the thermoset elastomeric element to a temperature of at least the glass transition temperature of the thermoset elastomeric element; adjusting the first shape of the thermoset elastomeric element to produce a second shape with at least one dimension greater than that of the first shape; and cooling the thermoset elastomeric element to a temperature below that of the glass transition temperature of the thermoset elastomeric element to produce the heat-shrink elastomeric element.
US11065805B2	Warpage reduction device and warpage reduction method A warpage reduction device the present disclosure includes a jig having a warped shape capable of distributing stress of a workpiece, a light source heating the workpiece so as to be flat, a pressurizer applying pressure to the heated workpiece to be pressed against the jig so as to be deformed, a cooler cooling the deformed workpiece, and a controller controlling operations of the light source, the pressurizer, and the cooler.
US11065804B2	Energy efficient blow molder control Blow molder system and associated method optimizes the performance, energy efficiency and/or operating costs of the blow molder. A blow molder controller executes a system model that relates blow molder input parameter changes to the characteristics of containers generated by the blow molder. Equipped with energy and/or operating cost data for operating the blow molder, the blow molder controller can select a set of blow molder input parameter changes for the blow molder that: drives the containers produced by the blow molder toward desired container characteristics, in an efficient amount of time, and in cost effective manner, considering the energy costs involved in implementing the changes.
US11065803B2	Preform conveying device, preform conveying method, and blow molding device A preform conveying device (100) of the invention includes a control unit that detects an arriving time at which a conveyor jig arrives at a reference position based on an output of a first encoder, and commands a second motor to move a conveyor arm to a target position at regular intervals from the arriving time. The target position in each command is a position obtained by adding, to a current position of the conveyor jig which is obtained based on a latest output of the first encoder which was obtained when the command has been issued, a moving distance by which the conveyor jig has advanced during a delay time T which spans from a time when the latest output is outputted from the first encoder to a time when the command is received by the second motor.
US11065802B2	Blow molding method and apparatus for forming squeezable plastic container A blow mold system including a mold body and a base portion. The mold body includes a central bore extending from a first end of the mold body to a second end of the mold body along a longitudinal axis. The first end is configured to receive a mold preform. The base portion includes a recess, and the base portion is arranged at the second end of the mold body such that the central bore and recess define a blow mold cavity in which a container may be formed from the mold preform. In embodiments, the blow mold system has at least two interchangeable base portions that allow for containers with differently-sized or differently-shaped necks to be formed.
US11065800B2	Granulator, nozzle arrangement for a granulator, and relevant operating method A nozzle arrangement for a granulator has a nozzle body with an inlet side as well as an outlet side, a nozzle plate with nozzle holes arranged on the outlet side for forming melt strands, and flow channels formed in the nozzle body and connected to the inlet side and the outlet side in a fluid-conducting manner for supplying a melt flow to a nozzle plate. An annular connection channel connects a plurality of flow channels in a fluid-conducting manner. A method for separating a melt flow into melt strands is also described.
US11065799B2	Adjustable venturi ring An apparatus includes an upper lip positioned with respect to an air flow passage. The upper lip is to direct air flow from the air flow passage around a bubble of blown film. The apparatus further includes a Venturi ring movably mounted with respect to the upper lip and adjustable in position with respect to the upper lip. The Venturi ring is to adjustably lock the bubble of blown film.
US11065796B2	System and method for continuously manufacturing cured membranes A method of continuously manufacturing a cured membrane includes continuously compounding and mixing a vulcanizable rubber composition in a mixing extruder while continuously removing gasses from the vulcanizable rubber composition during mixing with a vacuum. The vulcanizable rubber composition may be continuously extruded to form an extrudate, which may be continuously calendered to form a green membrane. The green membrane may be continuously cured, such as by a hot air conveyor curing system, to form a cured membrane.
US11065795B1	Molding system for preparing thermoplastic composite article The present disclosure provides a molding system for preparing an injection-molded plastic article. The molding system includes a molding machine; a mold disposed on the molding machine and having a mold cavity for being filled with a molding resin including a plurality of polymer chains; a processing module configured to generate an anisotropic viscosity distribution of the molding resin in the mold cavity based on a molding condition for the molding machine; wherein the anisotropic viscosity distribution of the molding resin is generated based in part on consideration of an integral effect of a volume fraction and an aspect ratio of the plurality of fibers; and a controller coupled to the processing module and configured to control the molding machine with the molding condition using the generated anisotropic viscosity distribution of the molding resin to perform an actual molding process for preparing the injection-molded plastic article.
US11065792B2	Injection moulding apparatus and method for injection moulding and IR-compatible display frame An injection moulding apparatus and method for producing a moulded article is disclosed herein. In a described embodiment, the method comprises: (i) securing a layer of film to a part of a first mould half at step 504; (ii) adjusting relative position of the first mould component and a second mould component to an initial moulding position at step 506 to define a mould cavity; (iii) injecting molten moulding material into the mould cavity at step 508 to enable the molten moulding material to contact the layer of protective film; (iv) moving a movable core at step 510 to compress the molten moulding material in the mould cavity; and (v) cooling the compressed molten moulding material at step 514 to bond the layer of film to the cooled moulding material to form the moulded article.
US11065790B2	Fluorinated copolymer composition, method for its production, and molded product To provide a fluorinated copolymer composition having improved impact resistance and excellent moldability without impairing the excellent heat resistance and mechanical properties inherent to a thermoplastic heat-resistant resin. This fluorinated copolymer composition comprises a thermoplastic resin A being a melt-moldable heat-resistant thermoplastic resin and a fluorinated elastomer B being a fluorinated elastic copolymer, wherein the fluorinated elastomer B is dispersed in the thermoplastic resin A, the number average particle diameter of the fluorinated elastomer B is from 1 to 300 μm, the volume ratio of the thermoplastic resin A to the fluorinated elastomer B is from 97:3 to 55:45, and the fluorinated copolymer composition has a flexural modulus of from 1,000 to 3,700 MPa.
US11065788B2	Method for manufacturing gloves A method for producing a glove includes a step of forming a dip-molded layer by dip-molding a latex composition containing a latex of a carboxyl group-containing conjugated diene rubber (A) that does not have an isoprene-derived monomer unit, and a metal compound (B) including a divalent or higher metal, and a step of irradiating the dip-molded layer with radiation.
US11065786B2	Mold for forming a joint spacer device or a part thereof A mold for forming a joint spacer device or a part thereof includes a rigid container body having a first perimeter profile delimiting a first molding surface configured to shape a first portion of the joint spacer or part thereof; and a rigid cover provided with a second perimeter profile delimiting a second molding surface configured to shape a second portion of the joint spacer or part thereof. The rigid container body and the rigid cover are removably engageable to each other, at the first and the second perimeter profile, so as to delimit a cavity corresponding to the external configuration of the joint spacer or part thereof. The mold includes a weakening system on the rigid container body and on the rigid cover, making them separable into parts to enable the extraction of the spacer device or part thereof, molded therebetween.
US11065774B2	Slicing guide apparatus A slicing guide apparatus for reducing perishable foods into small, bite-sized pieces, the apparatus having a hollow cylindrical frame defining an open top end, an open bottom end, at least a first set of pair of elongated, vertical slots, at least a second set of pair of elongated, vertical slots that are perpendicular in orientation to the at least first set of pair of elongated, vertical slots, wherein the width of the at least first set of pair of elongated, vertical slots and of the at least second set of pair of elongated, vertical slots permits a cutting utensil to pass therethrough, at least one elongated, vertical rib that protrudes outward from the exterior of the frame and indicia affixed to the frame.
US11065769B2	Robot, method for operating the same, and server connected thereto A method of operating a robot includes detecting movement of a video call counterpart using a video call counterpart robot included in image data received from the video call counterpart robot; canceling movement of a user from detected movement of the video call counterpart; and determining motion corresponding to the canceled movement of the video call counterpart.
US11065768B2	Automatic calibration for camera-robot system with tool offsets A method is provided for automatically calibrating a camera-robot system having tool offsets.
US11065763B2	Clamp installation apparatus, clamp installation system and method of installing a clamp A clamp installation apparatus includes a robot arm pedestal having a rotary table; a robot arm installed on the rotary table of the robot arm pedestal and having a plurality of arms and a plurality of joints; a robot hand installed to a forefront arm of the plurality of arms; and a control device. The robot hand includes: a clamp holding section configured to hold the clamp; a fastening section configured to fasten an engaging section of the clamp to give a clamp force to a work; and a measuring section configured to collect position data of a predetermined member of the clamp. The clamp can be automatically installed and removed. Also, the heat curing can be carried out in the condition to have installed the clamp.
US11065761B2	Robotic picking training technique A method of training a robot to pick a plurality of articles includes determining an identity of an article and determining if the article has a uniform distribution of weight. If the article has a uniform distribution of weight, a three-dimensional (3D) model of the article is created and stored in a database record associated with the identity. If the article does not have a uniform distribution of weight, a 3D model is created, two-dimensional (2D) images of each side of the article are created, and a 3D center of gravity of the article is determined. The 3D model, the 2D images, and the 3D center of gravity of the article are stored in a database record associated with the identity of the article.
US11065759B2	Articulated arm apparatus A hermetically sealed multi-axis articulated arm apparatus for use within a sealable isolator chamber is disclosed. In one general aspect, it comprises a rotational shaft that passes through an opening in the chamber, a sealing member disposed within the chamber for sealing the shaft to an inner surface of the chamber, interconnected hermetically sealed arm segments operably attached to the linear motion shaft; an end effector operably attached to a terminal arm segment among the arm segments, and at least one fully enclosed drive system for driving and controlling the shaft and the arm segments. The rotational shaft can further be a linear motion shaft for which the sealing member is a bellows. The materials for the parts of the apparatus exposed to the atmosphere of the chamber can be compatible with an aseptic and cleanable environment and the surfaces of the arm segments can be shaped to avoid pooling of contaminants.
US11065756B2	Tool bag carrying assembly A tool bag carrying assembly comprising a supporting clip for clamping a tool bag to a mounting structure. The clip includes a first frame and a second frame that are pivotably connected to one another, such as by a friction hinge. The first frame can include a pair of sloped arms and a support bar. A rotatable cylinder can slide over the support bar and rotate freely about a transverse axis over the support bar, so as to reduce friction between tool bag and clip. The sloped arms can form an open segment that enables ingress and egress of the tool bag onto the rotatable cylinder. The second frame can include a pair of mount legs and a mount bar that slide into the mounting structure as the first frame presses against the mounting structure from an opposing side.
US11065745B2	Fastener cartridge A fastener cartridge can be used with a shaft of a tool during an orthopedic procedure. The fastener cartridge can have a main housing that can be attached to fastener housing including a fastener chamber and a backstop component. The fastener chamber includes a plurality of non-flexible tabs and the backstop component includes a plurality of resiliently flexible tabs. The fastener housing is configured to include a plurality of fasteners that are arranged therein such that the longitudinal axes of the fastener chamber and the plurality of fasteners are collinear. The plurality non-flexible tabs prevent one of the fasteners from inadvertently passing entirely out of an outlet of the fastener chamber and the plurality of resiliently flexible tabs allow the fasteners to move axially in the first direction and restrict movement of the fasteners in a second direction opposite the first direction.
US11065742B1	Rotation and removal tool for airless sprayer tips A rotation and removal tool for airless sprayer tips aids in manually manipulating sprayer tips of airless paint sprayers. The rotation and removal tool is provided with an elongated body and a tip receptacle traversing into and within the elongated body. The tip receptacle is configured to releasably receive a sprayer tip of an airless paint sprayer to be retained therein so that the elongated body may be used as a handle to rotate, pull, push or otherwise manipulate a sprayer tip, facilitating easier removal or other maintenance is the sprayer tip has become clogged or jammed. At least one angled grip feature may be provided for ergonomic. A pry lip may be provided to enable can opening functionality. A wrench feature, driver feature, and cleaning prongs may also be included.
US11065740B2	Fixed adjustable wrench A fixed adjustable wrench. The fixed adjustable wrench includes a handle having a fixed jaw and an adjustable jaw forming a gap therebetween. The adjustable jaw is slidable along a shoulder and is adapted to cooperate with the fixed jaw to secure an object within the gap. An engagement member having a first set of teeth is configured to selectively interlock with a second set of teeth of the adjustable jaw. A second end of the engagement member is operably connected to a lever that is selectively moveable between an engagement position and a disengagement position. In the engagement position, the engagement member is coupled to the adjustable jaw via an interlocking of the first set of teeth and the second set of teeth. In the disengagement position, the engagement member is disengaged from the adjustable jaw allowing selective positioning of the adjustable jaw.
US11065736B2	Tote tray Plumbers are often required to carry out various tasks on water pipes including measuring, cutting, bending, threading, joining, soldering and marking positions on pipes. Each of these activities requires the pipe to be held securely by the plumber (for instance in one hand, or under one foot, while the task itself is carried out using the free hand(s). The present invention is a tote tray provided with a clamp 15 connected to the open-top box, the clamp configured for releasably gripping a pipe 17. In this way, a plumber may place a pipe 17 within the clamp 15 and securely grip it therein, and may then carry out various types of work on the pipe 17 without the need to hold the pipe 17 manually in position. Once work on the pipe 17 has been completed, the user may release the clamp's grip on the pipe 17.
US11065734B2	Film thickness measuring device and polishing device The present invention improves versatility of a film thickness measuring device. The trigger sensor 220 includes a proximity sensor 222 and a dog 224, and outputs a trigger signal indicating that a polishing table 110 makes one revolution. The eddy current sensor 210 measures a film thickness of a subject to be polished 102 at a timing based on the trigger signal output from the trigger sensor 220. The dog 224 is disposed in an opposite region 250 located at the opposite side of a rotation axis CW of the top ring 116 with respect to a rotation axis CT of the polishing table 110. Further, the eddy current sensor 210 and the proximity sensor 222 are disposed at the polishing table 110 so as to be located in the opposite region 250 when the trigger signal is output from the trigger sensor 220.
US11065733B2	Methods and tool for maintenance of hard surfaces, and a method for manufacturing such a tool A method is disclosed for treating or maintaining a hard surface comprising a stone or stone-like material, the method comprising treatment of the surface with a flexible pad, in the presence of abrasive particles, bonded to the pad, on a contact surface between the pad and the hard surface, wherein the abrasive particles comprise diamond particles, and the treatment is performed in the absence of an effective amount of crystallization agent on the contact surface. The treatment is performed on a substantially regular basis, such as daily, weekly or monthly, and the treatment is performed using a pad comprising an open, lofty, three dimensional non-woven webs of fibers. A tool for use in the method is also provided, as well as a floor-surfacing machine comprising such a tool and a method for manufacturing such a tool. Furthermore, methods for treating or maintaining hard, smooth surfaces such as wood, polymer material, lacquer, linoleum, gelcoat, glass and automotive enamel are disclosed.
US11065727B2	System for assembling a cartridge for a smoking article and associated method The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. The cartridges may be assembled by coupling a base of the cartridge to a carriage that is transported via a track. The track transports the carriages between various substations at which one or more parts are added to the base. The carriage may be lifted from the track by a lifter mechanism at each substation in order to perform assembly operations on the base. An inspection system may inspect the cartridges at various stages of completion at or between the various substations.
US11065722B2	Laser processing apparatus and laser processing method A laser processing apparatus includes: a light flux separating-and-combining device configured to polarize and separate a laser light into two polarized light fluxes having polarization orthogonal to each other and emit the two light fluxes with their optical paths matching each other toward different regions of a spatial light modulator, and configured to combine the two polarized light fluxes modulated by the spatial light modulator and emit the two light fluxes toward a condenser lens; and a controller configured to control hologram patterns presented by the spatial light modulator for respective regions of the spatial light modulator irradiated with the two polarized light fluxes such that the laser light is condensed by the condenser lens at two positions different from each other in a thickness direction inside of the wafer and the same as each other in a relative movement direction of the laser light to form modified regions.
US11065719B2	Laser-interference surface preparation for enhanced coating adhesion A coated article includes a substrate having an interference laser-treated surface portion, and a single-stage coating adhered directly to the interference laser-treated surface portion. A system and method for making a coated article are also disclosed.
US11065712B2	Resistance spot welding method A resistance spot welding method of squeezing parts to be welded, which are a plurality of overlapping metal sheets, by a pair of electrodes and passing a current while applying an electrode force to join the parts to be welded comprises: a first step of passing a current by constant current control to form a fusion zone having a diameter of not less than 2√{square root over (t)}, expressed in mm, between the metal sheets, where t, expressed in mm, is a sheet thickness of a thinnest metal sheet of the metal sheets; a second step of cooling the fusion zone to have a diameter of not greater than 80% of D, where D, expressed in mm, is a diameter of the fusion zone formed in the first step; and a third step of performing adaptive control welding by controlling a current passage amount according to a target that is set.
US11065711B2	High aspect ratio weld face design for dissimilar metal welding An electrical resistance spot welding electrode is disclosed for contact with a narrow or other selected spot weld region in a steel workpiece in a stack-up with an aluminum alloy workpiece for use in a spot welding method in which the weld nugget is carefully formed in the aluminum workpiece at the interface of the stack-up. The welding face of the welding electrode for contact with the steel workpiece is shaped with an aspect ratio greater than one, which fits against the contact surface of the steel workpiece, while the welding face for the aluminum-contacting weld electrode is circular (with an aspect ratio equal to one). The stack-up of workpieces may include a single steel workpiece facing two aluminum workpieces in a sandwich type stack-up or two steel workpieces facing a single aluminum workpiece with the outer steel workpiece having the narrow contact surface for the steel welding electrode.
US11065709B2	Metal analyzing plasma CNC cutting machine and associated methods A plasma computer numerically controlled (CNC) cutting machine is controlled by a computers. In an embodiment, the computer executes a CNC program to control movement of a plasma torch to cut parts from a workpiece while a spectrometer determines emissions spectra of light emitted in a brief time window as the torch begins to cut the workpiece. The spectrometer cooperates with the computer to analyze the metal as it is being cut by the CNC cutting machine and determine a composition. In embodiments, the composition is compared to an expected composition and saved in a database with identifying information; in a particular embodiment the database is queried to provide identifying information of metal having similar composition to the workpiece.
US11065708B2	Methods and systems for plasma machine processing of steel beams and other long products using a pantograph plate bevelling gantry-type plasma cutting machine A plasma-torch cutting machine gantry moves in a first axis and the torch mounted through a pantograph to a drive box moves along the gantry in a second axis. The drive box rotates the torch about a third axis, and tilts the torch about a fourth axis. The drive box moves vertically in a fifth axis. The torch is mountable with tip at pantograph focal point or in an extended position. A controller firmware computes and apply offsets in the first, second and fifth axis to maintain the plasma torch tip in desired position despite the torch being mounted in extended position, rotation and tilt of the torch. In embodiments the torch is rotatable −/+90 degrees from vertical; and a laser scanner maps surfaces and edges of beams to determine movements and rotations for cutting beams.
US11065707B2	Systems and methods supporting predictive and preventative maintenance Embodiments of systems and methods for supporting predictive and preventative maintenance are disclosed. One embodiment includes manufacturing cells within a manufacturing environment, where each manufacturing cell includes a cell controller and welding equipment, cutting equipment, and/or additive manufacturing equipment. A communication network supports data communications between a central controller and the cell controller of each of the manufacturing cells. The central controller collects cell data from the cell controller of each of the manufacturing cells, via the communication network. The cell data is related to the operation, performance, and/or servicing of a same component type of each of the manufacturing cells to form a set of aggregated cell data for the component type. The central controller also analyzes the set of aggregated cell data to generate a predictive model related to future maintenance of the component type.
US11065706B2	Hybrid manual and automated welding Hybrid manual and automated welding systems and methods are described. A hand-held welding tool is manually positioned to engage a workpiece. A weld is started from an initial position based on a first manual operator event. A welding heat source is automatically or autonomously moved along the weld relative to the workpiece from the first position to a second position relative to the workpiece during welding.
US11065703B1	Emissions collection system and methods An emissions collection system that includes a containment system, the containment system including a plurality of walls and a roof structure that together form an internal chamber; wherein chamber inlets are formed in one wall of the plurality of walls; and wherein chamber outlets are formed in either another wall of the plurality of walls or the roof structure. A filter assembly includes a filter that collects emissions generated within the internal chamber; and a duct system that places the chamber outlets in fluid communication with the filter assembly; wherein the filter assembly is sized and configured to move air through the chamber inlets, the internal chamber, the chamber outlets, the duct system, and the filter to collect emissions generated within the internal chamber.
US11065699B2	Method and apparatus for cutting true with a round saw Process accuracy and throughput in a system for processing timber and lumber with a circular gang saw can be improved by measuring a sawing force and a guide friction force near an end of one or more saw arbors and incorporating the force measurement into a process control system to adjust the workpiece feed speed (or other process parameters) to achieve better results.
US11065696B1	System, apparatus, and method for removing a portion of a structure A method for removing a portion of a structure is disclosed. The method includes attaching a first elongated member to the portion of the structure, receiving a second elongated member of a drilling assembly with the first elongated member, drilling into the structure with the drilling assembly while receiving the second elongated member with the first elongated member, and removing the portion of the structure that is attached to the first elongated member while urging the first elongated member with the second elongated member.
US11065693B2	Cutting tool shim and cutting tool A cutting tool shim is to be disposed between a cutting insert and a holder and to be fixed to the holder. The ridgeline between the flank face and the rake face forms a cutting edge. The cutting edge includes an arc-shaped portion. A coolant supply path for jetting coolant to the arc-shaped portion is provided in the cutting tool shim, the coolant being supplied from the holder. The coolant supply path includes a lead-in port for leading the coolant from the holder to the coolant supply path, and a jetting port for arc-shaped portion for jetting the coolant to the arc-shaped portion. The jetting port for arc-shaped portion has a curved shape along the arc-shaped portion. The distance between the jetting port for arc-shaped portion and the arc-shaped portion is not less than 2.2 mm and not more than 8.1 mm.
US11065689B2	Additive manufacturing with polygon and galvo mirror scanners An additive manufacturing system includes a platform, a dispenser to dispense a plurality of layers of feed material on a top surface of the platform, a light source to generate a first light beam and a second light beam, a polygon mirror scanner, a galvo mirror scanner positioned adjacent to the polygon mirror scanner, and a controller. The controller is coupled to the light source, the polygon mirror scanner and the galvo mirror scanner, and the controller is configured to cause the light source and polygon mirror scanner to apply the first light beam to a region of the layer of feed material, and to cause the light source and galvo mirror scanner to apply the second light beam to at least a portion of the region of the layer of feed material.
US11065687B2	Method for manufacturing metal product with two blanks A method for manufacturing hollow and other metal products of irregular shape provides metal powder and binding agent, and the two are feed-mixed and heated to a plastic state. The feed-mix is injected in a mold cavity of a first injection mold to form a first blank, and injected in a mold cavity of a second injection mold to form a second blank. The first blank and the second blank are welded together to form a built-up blank which is degreased to remove the binding agent therein. The degreased built-up blank is sintered to obtain the metal product of irregular shape.
US11065686B2	Method for sintering metals, non-oxide ceramics and other oxidation-sensitive materials A method for sintering metallic and/or non-oxide components includes completely encapsulating, in a metal halide salt, a green body comprising at least one metallic and/or non-oxide powder, and compressing the encapsulated green body so as to be gastight. The method further includes heating, together with a metal halide salt in the presence of oxygen up to sintering temperatures, the compressed, encapsulated green body. The method additionally includes at least partially dissolving, after cooling, the metal halide salt in a liquid so that the sintered component can be removed.
US11065684B2	Magnesium oxide powder, production method therefor, thermally-conductive resin composition, thermally-conductive grease, and thermally-conductive coating material A magnesium oxide powder has: a median diameter (D50) of 5 to 100 μm; a MgO purity of 98% by mass or more; a Ca compound content of 2% by mass or less in terms of CaO; and when the magnesium oxide powder is immersed in pure water and allowed to stand at 95° C. for 24 hours, a mass ratio of calcium ions to magnesium ions, Ca/Mg, in an aqueous solution of 10 or less.
US11065682B2	Forming of battery components A mould for forming battery components includes a first mould body having a first plurality of mould cavities and a second mould body having a second plurality of mould cavities. The first mould body and the second mould body are configured to be moveable between a moulding position in which the first plurality and second plurality of mould cavities are aligned, and a fill position in which the first plurality and second plurality of mould cavities are displaced from the aligned position and are proximal to a molten metal feed.
US11065681B2	Brake carrier casting and a method of making a brake carrier casting A brake carrier casting and a method of making a brake carrier casting. The brake carrier casting may have a first side portion and a second side portion that may be connected by a first bridge and a second bridge. The first side portion, second side portion, first bridge, and second bridge may define an opening of the brake carrier casting.
US11065675B2	Orbital forging device, method for orbital forging, method for manufacturing hub unit bearing using method for orbital forging, and method for manufacturing vehicle Provided is construction which is able to downsize an orbital forging device comprising a spherical seat with shaft that swings and rotates with a molding die. The end section on the other side in the axial direction of the swinging shaft 13 is supported with respect to the driving mechanism 17 in a state where the movement toward one side in the axial direction (lower side) is prevented, and a member for preventing the swinging shaft 13 from moving toward the one side in the axial direction with respect to the frame 10 is not assembled in a section which is located between the convex spherical seat 14 and the driving mechanism 17 in the axial direction of the swinging shaft 13.
US11065669B1	Forward stroke pipe fitting swage machine systems and methods Techniques for implementing and/or operating a system that includes a pipe fitting to be secured to a pipe segment, in which the pipe fitting includes a grab ring having a grab notch and a fitting jacket to be conformally deformed around tubing of the pipe segment to facilitate securing the pipe fitting to the pipe segment. Additionally, the system includes a swage machine, which includes a grab plate having a grab tab that matingly interlocks with the grab notch on the grab ring to facilitate securing the pipe fitting to the swage machine, a die plate in which a die is loaded, and a swaging actuator secured to the die plate. The swage machine operates the swaging actuator to push the die plate over the fitting jacket of the pipe fitting to facilitate conformally deforming the fitting jacket around the tubing of the pipe segment via a forward stroke.
US11065668B2	Method and apparatus for forming a nacelle leading edge An apparatus for forming a nacelle leading edge includes an actuation assembly, a punch, and a die. The punch is in communication with the actuation assembly and annularly disposed about a first axis. The punch is configured to mate with an interior surface of a preform. The die is in communication with the actuation assembly and disposed within the first axis. The die is configured to retain an exterior surface of the preform. The actuation assembly is configured to effect relative motion between the punch and the preform. The actuation assembly is configured to offset the punch so that the punch is annularly disposed about a second axis, different than the first axis.
US11065666B2	Burring method and burring device A burring method includes: a placement process of disposing a sheet-shaped workpiece formed with a through hole such that a punch is positioned on one sheet thickness direction side of the workpiece and a pad is positioned on the opposite side to the one sheet thickness direction side of the workpiece; and an extrusion process of forming a flange by moving the punch toward the opposite side relative to the workpiece and extruding a peripheral rim of the through hole in the workpiece with the punch in a state in which the peripheral rim of the through hole is pressed by the punch and the pad in the sheet thickness direction of the workpiece.
US11065665B2	Progressive die machine and method for manufacturing laminated iron cores by using same When provisionally blanking a lamination sheet by using a punch for provisional blanking and a counter punch, the displacement of pilot holes located around the lamination sheet is minimized. The progressive die machine (1) comprises a pilot hole punch (72), a punch (9) for provisionally punching an iron core laminate (2) from a strip (W) formed with pilot holes (P), a counter punch (31) provided in a lower die assembly (5) and configured to push the iron core laminate (2) against the punch (9), a stripper plate (13) for separating the strip (W) from the provisional blanking punch after a provisional punching, a punch (10) for completely separating the iron core laminate from the strip. At least a part of the stripper plate (13) associated with the provisionally blanking is not in contact with the strip, and at least a part of an outer peripheral part of the provisionally blanked lamination sheet is formed with a connecting portion (79) connected to the strip.
US11065660B2	Production installation having a clamping tool and method for adapting a total length of a bending edge of the clamping tool A production installation for producing workpieces from sheet metal by forming in a bending operation includes a bending machine and a clamping tool having at least one lower clamping jaw and an upper clamping jaw set including first upper clamping jaws and a second upper clamping jaw. The second upper clamping jaw has a clamping jaw part at each of the two second upper clamping jaw end sections, the clamping jaw parts being movable from a working to a pull-out position. At least one first upper clamping jaw is arranged on both sides of the second upper clamping jaw. The first upper clamping jaws have a first horn at each of the first end regions of the first upper clamping jaws facing away from the second upper clamping jaw. A method adapts a total length of a bending edge of a clamping jaw set of this production installation.
US11065659B2	Harsh environment enclosure A harsh environment enclosure for use with sensor systems, such as cameras. The enclosure can include a housing having an end wall, sidewalls, a top wall, and a bottom wall. A door is hinged to the top wall. The enclosure can have a linkage assembly including a door lever having an elongate first end portion connected to the door, a laterally extending second end portion, and an elbow positioned therebetween. A pivot arm having a proximal end is connected to an interior surface of the housing and a distal end of the pivot arm is connected to the elbow. An actuator can be connected between the housing and the laterally extending second end portion. The linear actuator can be positioned with respect to the door lever and pivot arm to move the door to an open position when extended and a closed position when retracted.
US11065658B2	Notching equipment for steel strip, method of notching steel strip, cold rolling facility, and method of cold rolling Notching equipment for a steel strip, a method of notching a steel strip, a cold rolling equipment, and a method of cold rolling that make it possible to perform cold rolling on a material without weld breaks, even if the material is a brittle material or a high alloy material such as a silicon steel sheet or a high-tensile steel sheet with high Si and Mn contents. The notching equipment includes a shearing device and a grinding device. The shearing device performs shearing on both edge portions in the steel-strip width direction including the joint to form a first notch. The grinding device grinds end surfaces of both the edge portions of the joint in the steel-strip width direction to form a second notch.
US11065656B2	Method and apparatus for producing a product The present invention relates to a method and apparatus for producing a product by hydrolyzing a raw material containing vegetable waste comprising, a hydrolysis treatment step of subjecting the raw material to a hydrolysis treatment with steam by a hydrolysis treatment apparatus, a washing step of washing the hydrolyzed raw material with a washing liquid by a cleaning apparatus, and a solid-liquid separation step of separating the washed raw material into a solid component and a liquid component by a solid-liquid separation apparatus, wherein at least one of the solid content or the liquid con-tent is used as the product.
US11065655B2	Apparatuses, systems, and methods for cleaning A cleaning apparatus includes a nozzle assembly and an arm supporting the nozzle assembly. In some embodiments, the arm includes a first rotatable arm member defining a first axis and a second rotatable arm member defining a second axis and connected to the first rotatable member. In certain examples, the first rotatable arm is rotatable about the first axis and the second rotatable arm is rotatable about the second axis. The cleaning apparatus also includes at least one sensor on the arm and configured to detect a position of the nozzle assembly based on rotation of the first rotatable arm or the second rotatable arm
US11065647B2	Adjustable vibratory drive system A vibratory drive system, suitable for a material screening apparatus, includes rotatable drive shafts each having a centre of mass offset from its rotational axis. A respective drive mechanism is coupled to each drive shaft and is controlled by a controller. The controller adjusts the relative rotational speed of the drive shafts to adjust the relative angular position of the respective centre of mass of the drive shafts. This adjustment allows the vibratory characteristics of the drive system to be changed without having to halt the drive system.
US11065643B2	Ultrasonic imaging and energy delivery device and method An ultrasonic device includes a driving circuit to provide drive power, a first transducer array to generate ultrasonic waves, the first transducer array being connected to receive power from the driving circuit, and a second transducer array to detect reflected or elicited ultrasonic waves incident on the device from a target and generate a signal based on those waves, the second transducer array being acoustically transmissive and disposed over the first transducer array such that the generated ultrasonic waves pass through the second transducer array. The second array is tuned to operate on top of the first. The functions of the two arrays may be reversed and the array tuned to operate with the first array receiving and the second array transmitting.
US11065640B2	System, method, and apparatus for hot melt adhesive application A hot melt adhesive applicator with one or more air outlets configured to direct a pressurized heated air stream transversely toward hot melt adhesive discharged through a discharge port of the applicator. A controller can switch between two modes, a discharge completion mode where the heated air stream pressure is temporarily increased to automatically eliminate or reduce hot melt adhesive stringing and an application mode where the heated air stream assists in heating or maintaining the hot melt adhesive at or above melt temperature.
US11065638B2	Application device A sealing agent (25) sent from a nozzle tube (36) to a nozzle main body (37) is passed through a main body flow channel portion (37a), a connecting portion (37c), a first flow channel portion (37b), and plural second flow channel portions (37d), sent to a chamber (37e), and discharged from a nozzle port (37f) to the outside. Since the second flow channel portions (37d) are smaller than a downstream end of the first flow channel portion (37b), the sealing agent (25) in the first flow channel portion (37b) is vigorously sent to the chamber (37e), and discharged from the nozzle port (37f) to the outside. As a result, substantially the same quantity of the sealing agent (25) is discharged in the entire range of the chamber (37e).
US11065635B2	Container appendage A container appendage is disclosed comprising a mounting ring having an upper surface, a lower surface, an exterior edge and an interior edge for defining a mounting aperture. A platform member is coupled to the mounting ring. The mounting ring is coupled between the bottle and the spray body for defining a mounting ring couple. The platform member cantilevers above the handling neck and adjacent to the rear surface for defining a rear ergonomical handling member for conforming to the hand and improving ergonomical grasping of the handling neck, actuating the trigger and lifting the spray bottle by the hand.
US11065633B2	Spraying apparatus A spraying apparatus includes a spraying apparatus main body, a liquid introduction portion, a gas-liquid spout portion, a gas introduction portion, a liquid inlet, a first gas inlet passage, a second gas inlet passage, and a spout. The first gas inlet passage is provided at at least one place of the annular gas introduction portion so as to communicate with the gas flow passage and the gas-liquid mixer, and allows a gas flow flowing through the gas flow passage to enter the gas-liquid mixer. The second gas inlet passage has a gas inlet having a predetermined area ratio, is provided on a downstream side of the first gas inlet passage of the gas introduction portion, and communicates with the gas flow passage and the gas-liquid mixer.
US11065631B2	Spraying nozzle with pre-atomization narrowing, and spraying head and spraying device comprising such a nozzle A spraying nozzle, intended for spraying a product, defines a passage for the circulation of the product through the nozzle, wherein the passage opens through a wide connection orifice to the outside of the nozzle at an upstream end thereof, and through a narrow spraying orifice at a downstream end of the nozzle in order to spray the product; the passage has, between the connection orifice and the spraying orifice, at least one pre-atomization narrowing capable of atomizing the product, followed by a broadening downstream of the pre-atomization narrowing.
US11065626B2	Monitoring and control device for the automated optimization of the grinding line of a roller system and corresponding method A self-optimizing, adaptive product processing system and a corresponding method for grinding and/or crushing cereals and seeds. The grinding and/or crushing takes place in at least one roller mill which includes a roller pair. So as to detect the temperature of the surfaces of the rollers, at least two temperature sensors are disposed on at least one of the rollers. The detected temperature measurement values are used for optimal adjustment and signal generation of the roller setting.
US11065620B2	Removing bubbles in a microfluidic device Methods of removing bubbles from a microfluidic device are described where the flow is not stopped. Methods are described that combine pressure and flow to remove bubbles from a microfluidic device. Bubbles can be removed even where the device is made of a polymer that is largely gas impermeable.
US11065618B2	Flow balancing A device for controlling a fluid flow in an array of fluid pathways on a microfluidic chip is provided. The device comprising: two or more resistors provided upstream of the chip wherein each upstream resistor is configured to provide a resistance at an upstream end of a fluid pathway; two or more resistors provided downstream of the chip wherein each downstream resistor is configured to provide a resistance at a downstream end of a fluid pathway, wherein the values of the resistances are selected in order to control a proportion of fluid that flows through each fluid pathway.
US11065615B2	Assay modules having assay reagents and methods of making and using same We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays. Reagents may be present in free form or supported on solid phases including the surfaces of compartments (e.g., chambers, channels, flow cells, wells, etc.) in the assay modules or the surface of colloids, beads, or other particulate supports. In particular, dry reagents can be incorporated into the compartments of these assay modules and reconstituted prior to their use in accordance with the assay methods. A desiccant material may be used to maintain and stabilize these reagents in a dry state.
US11065613B2	Pipetting device, pipette tip coupler, and pipette tip: devices and methods Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, a discrete segment assembly, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the discrete segment assembly abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
US11065607B2	Vinylpyridine resin for catalyst supports, production method therefor, and catalyst for methanol carbonylation reaction A vinylpyridine resin for a catalyst support; a method for producing thereof; and a catalyst for carbonylation of methanol are disclosed. The vinylpyridine resin has: content of nitrogen derived from a pyridine group of 3.00% by mass or more and 8.00% by mass or less; degree of crosslinking of 35% by mole or more and 70% by mole or less; molar ratio C/N of carbon atoms to nitrogen atoms of 12.00 or more and 36.00 or less; total pore volume of 0.20 cc/g or more and 0.45 cc/g or less; specific surface area of 70.0 m2/g or more and 280 m2/g or less; average pore diameter of 5.0 nm or more and 25.0 nm or less; and proportion of a volume of pores having a pore diameter of 10 nm or more to a volume of the whole pores of 4.0% or more and 90.0% or less.
US11065605B2	Method of preparing a multi-component alloy catalyst A method for preparing a multi-component alloy catalyst on which a catalytic metal is supported includes preparing a carbon composite having a carbon support coated with a cationic polymer, supporting a catalytic metal containing at least two metal elements on the carbon composite to prepare an alloy catalyst precursor, and washing the alloy catalyst precursor to remove the cationic polymer.
US11065604B2	Catalyst for producing light aromatics with heavy aromatics, method for preparing the catalyst, and use thereof A catalyst for producing light aromatics with heavy aromatics, a method for preparing the catalyst, and a use thereof are disclosed. The catalyst comprises a carrier, component (1), and component (2), wherein component (1) comprises one metal element or more metal elements selected from a group consisting of Pt, Pd, Ir, and Rh, and component (2) comprises one metal element or more metal elements selected from a group consisting of IA group, IIA group, IIIA group, IVA group, IB group, IIB group, IIIB group, IVB group, VB group, VIB group, VIIB group, La group, and VIII group other than Pt, Pd, Ir, and Rh. The catalyst can be used for producing light aromatics with heavy aromatics, whereby heavy aromatics hydrogenation selectivity and light aromatics yield can be improved.
US11065599B2	Resin beads and use in processing of aqueous solutions Provided is a resin bead comprising functional groups of structure (S1).
US11065597B2	Xenon adsorbent A xenon adsorbent capable of efficiently adsorbing xenon, even at a low concentration, from a mixture gas is Provided.A xenon adsorbent comprising a zeolite having a pore size in the range of 3.5 to 5 Å and a silica alumina molar ratio in the range of 10 to 30.
US11065594B2	Continuous flow process for preparing conducting polymers The present disclosure relates to a continuous flow process for preparing conducting polymers, for example polyaniline. The continuous flow process can provide a controlled synthesis of a conducting polymer from an emulsion comprising a polymerizable organic monomer and a free radical initiator in flow within a temperature controlled continuous flow reactor comprising at least one mixing element. The present disclosure also relates to the conducting polymers prepared by the continuous flow process.
US11065593B2	Microcapsules encapsulating a reflective agent Microcapsules encapsulating a reflective agent are provided herein. The microcapsules are comprised of an inner core, which comprises the reflective agent and optionally an oily substance, and an outer shell formed of wall-forming polymeric materials. The microcapsules may further comprise an opaque substance and/or a fatty acyl salt in the outer shell. Processes of preparing the microcapsules are also provided.
US11065586B2	Porous support-zeolite membrane composite and process for producing porous support-zeolite membrane composite The present invention relates to a process for producing a porous support-zeolite membrane composite, which comprises forming a CHA type zeolite membrane on a porous support by a hydrothermal synthesis in the presence of seed crystals, wherein an FAU type zeolite is used as the seed crystals.
US11065585B2	Synthetic membranes and methods of use thereof The present invention relates to synthetic membranes and use of these synthetic membranes for isolation of volatile organic compounds and purification of water. The synthetic membrane includes a hydrophobic polymer layer located on a polymeric membrane support layer. The invention includes a method of isolating volatile organic compounds with the synthetic membrane by contacting a volatile organic mixture with the hydrophobic polymer layer of the synthetic membrane and removing volatile organic compounds from the polymeric membrane support layer of the synthetic membrane by a process of pervaporation. The invention also includes a method of purifying water with the synthetic membrane by contacting an ionic solution with the hydrophobic polymer layer of the synthetic membrane and removing water from the polymeric membrane support layer of the synthetic membrane by a process of reverse osmosis. The invention also relates to methods of isolating non-polar gases by gas fractionation.
US11065582B2	Computer-readable recording medium on which clogging location specification program for separation membrane module is recorded, water production system, and water production method The present invention relates to a computer-readable recording medium having recorded thereon a clogging location determination program for a separation membrane module, in which, in order to determine a clogging location of a separation membrane module in a fresh water generation system for obtaining treated water by filtrating water to be treated by a separation membrane module having a separation membrane, a computer is caused to function as a clogging location determination means for determining a clogging location of the separation membrane module from a resistance in a lower part of the separation membrane module, a filtration resistance of a hollow-fiber membrane, and a resistance in an upper part of the separation membrane module.
US11065579B2	Catalytic combustion in low temperature, humid conditions Methods are disclosed for achieving the catalytic combustion of a gaseous species in low temperature humid environments. The methods comprise the steps of obtaining a combustion catalyst composition comprising an amount of a precious metal supported on an ion-exchangeable alkali metal titanate substrate, and then exposing the species to the combustion catalyst composition in the presence of an oxygen containing gas and water vapour at a catalysis temperature below 200° C. and at a relative humidity above 0.5%. A novel desiccant-coupled catalytic combustion process and system are also disclosed.
US11065578B2	Control of wet scrubber oxidation inhibitor and byproduct recovery The present disclose is directed to a method for controlling iodine levels in wet scrubbers, and, in particular, recirculating wet scrubbers by removing the iodine from the scrubbing solution, such as by using ion exchange, absorption, adsorption, precipitation, filtration, solvent extraction, ion pair extraction, and an aqueous two-phase extraction.
US11065577B2	Process for the production of copper sulfide A process for preparing a copper sulfide of the formula CuxSy, wherein the process comprises the following steps: (i) reacting an aqueous solution of a copper salt with a molar excess of a sulfiding agent so as to precipitate copper sulfide from the solution; (ii) isolating the copper sulfide precipitate from the reaction mixture; and (iii) drying the copper sulfide precipitate at a temperature of less than 100° C., wherein x and y are integer or non-integer values.
US11065572B2	Integrated treatment system for composite waste gas including nitrogen oxides, chlorofluorocarbons, hydrochlorofluorocarbons, hydrofluorocarbons, and perfluorinated compounds Disclosed is a system for integrally treating a composite waste gas including nitrogen oxides (NOx and N2O), chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), and perfluorinated compounds (PFCs). The system includes a first wet processor configured to wash and adsorb dust including gases, SOx, and ash dissolved in water, a decomposing reactor configured to receive waste gas processed in the first wet processor and process nitrogen oxides (NOx and N2O), fluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), and perfluorinated compounds (PFCs) in the waste gas, and a second wet processor configured to receive the waste gas processed in the decomposing reactor and wash and adsorb the received waste gas. The system can efficiently treat a large amount of composite waste gas.
US11065571B2	Honeycomb filter Provided is a honeycomb filter, including: a pillar-shaped honeycomb substrate having an inflow end face and an outflow end face and including a porous partition wall surrounding a plurality of cells; and a plugging portion disposed at any one of ends of the cells at the inflow end face and at the outflow end face. In a cross section orthogonal to an extending direction of the cells, inflow cells have a pentagonal or a hexagonal shape, and outflow cells have a square shape. The cells are configured that the inflow cells surround one outflow cell and one side of an inflow cell and one side of an adjacent outflow cell are parallel to each other. The partition wall is configured that thickness of a first partition wall disposed between the inflow cells and the outflow cells is larger than thickness of a second partition wall disposed between the inflow cells.
US11065568B2	Smart filter module analysis system and associated methods A filter module analysis system configured for the analysis of a filter module having a filter element contained within a housing, the housing having an inlet, a clean outlet and a waste outlet. A clean outlet sensor assembly can be provided about the clean outlet, and a waste outlet sensor assembly can be provided about the waste outlet. A data collection and network communication mechanism can be configured to receive process and receive data from the clean and waste outlet sensor assemblies and transmit the data over a network to a server form storage and processing filter module statuses based on flow detected flow parameters.
US11065564B2	Pressure control device A pressure control device reliably preventing foreign matter from flowing beyond a filter unit to the downstream side. The pressure control device includes a body and a cylindrical filter unit. The body has a flow path including a groove and a widened part. A depth of the groove from an upper surface to a bottom is a first depth. The widened part is connected to the groove, extends from the upper surface to the bottom, and has a width larger than a width of the groove. The filter unit is housed along a depth direction of the widened part to capture foreign matter mixed in a fluid passing through the flow path. A depth of the widened part from the upper surface to a bottom surface is a second depth larger than the first depth. The widened part includes a receiving part that a part of the filter unit enters.
US11065561B2	Sample degasser dilution control system A degasser system may comprise a mass flow controller device and a sample pump coupled to a sample degasser for controlling the dilution of gases extracted from drilling fluid in the sample degasser by a dilution fluid, such as nitrogen gas. The mass flow controller may inject the dilution fluid into the tank of the sample degasser to dilute the gases extracted from the drilling fluid. The dilution fluid may be aspirated or sparged into the sample degasser. The sample pump may extract a sample of the gases separated from the drilling fluid by the sample degasser. The rate of injection of the dilution fluid into the sample degasser and the rate of extraction of the gas sample from the drilling fluid may be adjustable to control the dilution of the gas sample for analysis.
US11065559B2	Cyclonic inlet diverter A cyclonic inlet diverter for initiating the separation of a multi-phase inlet fluid flow comprises an enclosed tubular body mounted crosswise within a larger separator vessel. The inlet diverter includes a splitter plate positioned within a center portion of the tubular body and configured to split the inlet flow into a first stream and a second stream, and a swirl plate positioned on each side of the splitter plate with angled surfaces configured to increase the cyclonic motion of the first and second streams within the tubular body. The inlet diverter further includes elongate apertures formed through bottom sidewall portions of the tubular body on each side of the splitter plate, an axial aperture formed through opposing end caps of the tubular body, and at least one radial aperture formed through lateral sidewall portions of the tubular body proximate each opposing end cap.
US11065554B2	Toy with ejectable fitting A toy (1000) includes a toy body (100) and an accessory (200). The toy body (100) includes an accessory locking member (4) which cooperates with or is separated from the accessory (200) to position or eject the accessory (200). The accessory (200) is provided with a first clamping part (204) configured to clamp a toy disc (300).
US11065553B2	Systems and methods for securing a movable arm of a ride vehicle The ride vehicle system includes a ride vehicle having a ride vehicle base configured to interface with a ride track and move along the ride track. The ride vehicle also has a movable arm having a base end and a free end. The moveable arm moves along one or more motion-controlled axes. The movable arm is mounted to the ride vehicle at the base end. A ride seat is attached to the free end of the movable arm. A coupling device couples a first portion of the movable arm to the ride vehicle base, the ride seat to a second portion of the movable arm, the ride seat to the ride vehicle base, or some combination thereof.
US11065551B2	Virtual reality presentation of real world space Methods and systems are provided for delivering a virtual reality (VR) experience of a real world space to a remote user via a head mounted display (HMD). A method provides for sending a request for the VR experience of the real world space and identifying a viewing location made by the user. The method includes operations for mapping the viewing location to a real world capture system for capturing video and audio at a location that corresponds to the viewing location and receiving real world coordinates for the real world capture system. Further, the method accesses a user profile of the user and receives a video stream of the real world space captured by the real world capture system. The method is able to identify and reskin a real world object with a graphical content element by overlaying the graphical content item in place of the image data associated with the real world object.
US11065546B1	Distributed authority for peer gaming An application can be executed for multiple peers using a peer-to-peer network structure. State data for the peers can be compared to provide for authority on the session even though there is no dedicated authority component. Such an approach can help to maintain consistency across the distributed network, as well as to minimize the occurrence of cheating or manipulation of the data on the session. A set of state variables is selected, and peers use their local values for those variables to generate hashes to be sent to the other peers. The hash values are compared and any variations addressed accordingly. For any outlier peers that report different hash values, their state values can be adjusted to attempt to bring those outliers back in sync with the other peers. This can involve updating or rolling back specific parameter values for the outlier or all peers.
US11065542B2	Method and apparatus for determining user engagement in a videogame A method of determining user engagement in a game includes: receiving data from a plurality of remote entertainment devices at a server, the data from a respective entertainment device associating at least a first feature state of the game with an action by a user of that respective entertainment device indicative of a predetermined degree of engagement by the user with the game, aggregating the data received from the plurality of entertainment devices, and determining a level of correspondence between one or more feature states and user actions indicative of the predetermined degree of engagement.
US11065532B2	Split-screen presentation based on user location and controller location A method for managing multi-player interactivity with an interactive application is provided, including the following operations: determining locations of a first controller, a second controller, a first user, and a second user; pairing the first controller to the first user based on the location of the first controller and the location of the first user; pairing the second controller to the second user based on the location of the second controller and the location of the second user; presenting a split-screen view of the interactive application, wherein presenting the split-screen view includes setting positions of a first view and a second view within the split-screen view based on one or more of the locations of the first user, the second user, the first controller, or the second controller.
US11065531B2	Multi-layered game board A portable board game that allows the player to journey through different terrains, providing a fun and educational foundation for learning all types of information with a unique game board; the multidimensional game board allows for choice within the gaming experience. The polarities of game components all have a secure, designated spot within the board game case. This platform provides an addition outlet for absorbing information while having fun at the same time.
US11065530B2	Overlay for collectible trading cards An overlay having artwork printed thereon in a strategic location such that when placed over the front face of a card changes the look and appearance of the original artwork on the front face of the card. The overlay may be used with any type of card, but is preferably used with playing cards and trading cards, and is most preferably used with collectible trading cards.
US11065529B2	Method of and apparatus for changing a shape of a gliding surface of a gliding device A method of changing a shape of a gliding surface of a gliding device may involve, in response to longitudinal deflection of the gliding device, causing at least one force transfer element to move longitudinally relative to the gliding device. Causing the at least one force transfer element to move longitudinally relative to the gliding device may involve causing the at least one force transfer element to deflect first and second laterally opposite side elements of the gliding device along a portion of the gliding device extending longitudinally along a binding region of the gliding device. Apparatuses and gliding devices are also disclosed.
US11065524B2	Systems, methods, and articles of manufacture to measure, analyze and share golf swing and ball motion characteristics Disclosed herein is an electronic device holder comprising a body having a back portion, a first body end, a second body end, and a first and second side portion. The device holder further comprises a clamp on the back portion of the body that is configured to removably attach and secure the body of the electronic device holder to a golf club shaft. The clamp comprises a first and second arm portion each comprising a support portion, an arcuate portion, and a guide portion. The guide portions assist in aligning and inserting the electronic device holder onto the golf club shaft. Furthermore the first body end, the first side portion, and the second side portions of the holder body comprise curved portions that assist in securing the electronic device into the holder. Other embodiments and systems are described herein.
US11065518B2	Handle grip control device A handle grip control device configured to be removably secured to a handle of an instrument includes a body having a first outer surface and an inner surface, and a protrusion extending radially outwardly from a respective proximal end at the first outer surface of the body to a distal tip. The inner surface defines a cavity configured to receive handles of instruments, and the protrusion can define a second outer surface that includes a first and second sloped surfaces opposite to a bottom surface. A slope of the first sloped surface defines a first angle relative to a plane that is perpendicular to a longitudinal axis of the body, and a slope of the second sloped surface defines a second angle relative to the plane that is greater than the first angle.
US11065517B2	Golf club and golf club head structures A golf club head has a body having a ball striking face, a rear opposite the ball striking face, a crown, a sole, a heel, and a toe, the body having a void defined by a peripheral edge on the sole. The body further defines a cover that extends over the void and forms at least a portion of the crown. At least a portion of the peripheral edge of the void includes a lip extending from the peripheral edge inwardly into the void. The golf club head may additionally or alternately include one or more weight receptacles connected to the sole and having an opening in the sole, such that each weight receptacle is configured to receive insertion of a weight through the opening.
US11065513B2	Set of golf club heads and method of manufacture A co-forged iron type golf club is disclosed. More specifically, the present invention discloses an iron type golf club head from a pre-form billet that already contains two or more materials before the actual forging process resulting in a multi-material golf club head that doesn't require any post manufacturing operations such as machining, welding, swaging, gluing, and the like. The resultant golf club head may be capable of achieving center of gravity locations previously unachievable without utilizing this co-forging technique. The resultant golf club head may be used to create a set of golf club heads with center of gravity locations that are more advantageous throughout a set of golf clubs.
US11065512B2	Golf club head with heel-side weight plug A golf club head comprising a body with a heel-side sole opening in communication with a hosel bore, a removable shaft sleeve with a tip sized to fit within the hosel bore, and a weight plug sized to fit within, and at least partially fill, the heel-side opening is disclosed herein. The weight plug, which has a base end with a through-opening, a tip end with a flange, and a side opening in communication with the through-opening, is connected to the shaft sleeve with a screw. When the golf club head is fully assembled, a hosel flange is trapped between the weight plug and the tip end of the shaft sleeve, and tightening the screw causes the weight plug and the shaft sleeve to move towards one another.
US11065510B2	Golf ball An object of the present invention is to provide a golf ball having a low spin rate on driver shots. The present invention provides a golf ball comprising a spherical core and at least one cover layer covering the spherical core, wherein the spherical core is formed from a rubber composition containing (a) a base rubber, (b) a co-crosslinking agent, (c) a crosslinking initiator, and (d) a RAFT agent, (b) the co-crosslinking agent contains an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms and/or a metal salt thereof, and (d) the RAFT agent is a compound represented by the formula (1): in the formula (1), R represents a monovalent organic group, and Z represents a monovalent organic group.
US11065509B2	Golf ball An object of the present invention is to provide a golf ball having improved ball speed or aerodynamic performance on a rainy day or the like by controlling the formulation of the paint film. The present invention provides a golf ball comprising a golf ball body and a paint film covering the golf ball body, wherein a paint film surface of the golf ball has a water contact angle A1 of 70° or more and a water sliding angle B1 of less than 50°. The present invention also provides a golf ball comprising a golf ball body and a paint film covering the golf ball body, wherein when a sheet consisting of a slab formed from a composition constituting a golf ball body surface and a coating film formed by applying a paint constituting the paint film on the slab is prepared, a coating film surface of the sheet has a water contact angle A2 of 90° or more and a water sliding angle B2 of less than 52°.
US11065507B2	Multifunctional balance exercise machine A multifunctional balance exercise machine comprises a balancing mechanism including loading board, spring, elastic column, and motion-tracking sensor; a first display unit and an electronic control device loaded with motion sensor game program arranged on the exercise equipment; whereby when the fitness user stands on the loading board, the user body weight and the stress applied by feet transmit to the elastic column and the spring via the loading board, cause the elastic column and the spring compressed or stretched, and force the loading board to oscillate, then achieve the effect of balance exercise; furthermore, the motion tracking sensor transmit signal of oscillation data to electronic control device, the processor unit operates the data, and present the image of the motion sensor game via the first display unit to achieve entertaining effect of virtual reality game.
US11065504B2	Variable-resistance exercise machine with wireless communication for smart device control and interactive software applications A variable-resistance exercise machine with communication for smart device control and interactive software applications, comprising a network interface that receives input from a user device and provides output to a user device; a plurality of moving surfaces that each provide an independent degree of resistance to movement based on received input and that detect movement and provide output to a user device based on the movement; and a plurality of rigid rails that provide a rigid support for a human user to grasp, and that provide attachment points for a user to affix a variety of devices.
US11065502B2	Position adjusting device for exercising apparatus A height adjustment mechanism for exercising apparatus includes a first frame body and a second frame body being slidable relative to the first frame body in an adjusting direction. The second frame body has a series of positioning holes. A pressing member is disposed at one side of the first frame body for tightening or loosening the second frame body. A slidable block is limitedly movable along the first frame body in the adjusting direction. A pin member is received in the slidable block and operable to be engaged in a selected one of the positioning holes so that movement of the second frame body causes movement of the slidable block within a limited range. When the slidable block moves toward bottom of the limited range, the pressing member is pulled inward by at least one connecting arm to a tightening position to clamp the second frame body.
US11065499B2	Adjustable dumbbell An adjustable dumbbell assembly includes a dumbbell mechanism having two or more weight members engaged in a receptacle, and a handle bar engaged between the weight members, two catches slidably engaged in the handle bar and extendible out and engageable with the weight members for detachably attaching the weight members to the handle bar, two followers slidably engaged in the receptacle and each having a protrusion for engaging with the catches and for moving the catches to engage with the weight members, and for detachably attaching the weight members to the handle bar, and an actuating member engaged with the followers for actuating the followers to move the catches to engage with the weight members.
US11065495B1	Spring anchor bar and carriage stop assembly A coil spring anchor bar and carriage stop is disclosed for use in a reformer exercise apparatus to fasten ends of one or more coil springs extending from the movable carriage to the foot end of the reformer frame. The anchor bar and carriage stop includes an elongated metal plate having a longitudinally flat straight portion extending between first and second ends, a first longitudinally straight curved portion curved in a first direction and extending between and forming part of the first and second ends, and a second curved portion between the first and second ends curved in a direction opposite the first direction. A pair of spaced apart carriage stops extend orthogonally from the straight portion engage the movable carriage to maintain a predetermined minimum distance between the anchor bar and the carriage when the anchor bar is supported from the foot end of the reformer frame.
US11065492B2	Controlled medication denaturing composition and method In one aspect, a composition for decomposing pharmaceutically active agents comprises an oxidizer comprising a permanganate, and an isocyanurate; and an immobilizer. In another aspect, a composition comprises up to 50 wt. % of an oxidizer comprising potassium permanganate and sodium dichloroisocyanurate dehydrate, wherein the wt. % is based on a total weight of the composition.
US11065489B2	Fire protection sprinkler assemblies and installations with adjustable push-to-connect fittings Adjustable fire protection assemblies and methods are provided. The assembly includes a sprinkler having a body with an outer encasing surface and a deflector supported from the body. An escutcheon having a receiver and a rim surround the fire protection sprinkler to define an aperture between the receiver and the sprinkler. A push-to-connect fitting of the assembly includes a tubular member with an end for connection to a pipe and an internal conduit that receives the sprinkler body. A seal member and a retaining ring are disposed within the tubular member to form an adjustable seal and grip about the sprinkler body. A releasing member translates to disengage the retaining ring from the sprinkler body; and the escutcheon translates with respect to the tubular member in a sliding surface engagement to define an adjustable deflector-to-rim distance between the rim of the escutcheon and the deflector of the sprinkler.
US11065488B2	Repositionable console A vehicle includes a turntable rotatably coupled to a chassis, a platform coupled to the turntable, and a railing coupled to the platform. A control console includes a base section coupled to the turntable and spaced from the railing and a movable section that is movably coupled to the base section. An access opening is defined between the railing and the base section. The platform is accessible by an operator through the access opening. The movable section of the control console is selectively repositionable relative to the base section between a stowed position and an operating position. An operator interface of the movable section is configured to be accessed by the operator when the movable section is in the operating position. The movable section of the control console extends across the access opening when in the operating position, thereby limiting operator accessibility through the access opening.
US11065485B2	Fixed systems and methods for extinguishing industrial tank fires, with and without fixed roof, including aerated foam projecting nozzles and center directed nozzles Fixed systems and method for extinguishing large scale industrial tank fires, with and without fixed roofs, and featuring aerated foam projecting nozzles and including fixed center directed nozzles.
US11065483B2	Systems and methods for fire containment An apparatus for containing fires including a fire containment pouch that includes an upper portion and a lower portion, the fire containment pouch is a flame-resistant material. The upper portion includes a pouch section that is coated with an intumescent material and the lower portion including a cuff section. The upper portion and the lower portion juxtaposed one against each other to define an outer containment portion of elongate length from a top of the pouch section and a bottom of the cuff section. The fire containment pouch is adaptable to be pulled inside out thereby transforming the outer containment portion to an inner containment portion and a fastener secured to the bottom of the cuff section to seal an object within the inner containment portion after the fire containment pouch has been pulled inside out.
US11065474B2	Patient alignment method and system using light field and light reflector during radiation therapy A system to align an object using a light reflector, including: an input unit for pre-setting a first region in which radiation is to be emitted to the object; a display unit for displaying information on the first region; a radiation unit for emitting radiation to the first region; a reflector formed to correspond to the shape of the first region and configured to be attached to the first region; a light unit for emitting light in the same direction as the radiation to the first region; a camera for photographing a region of the reflector when the reflector reflects light emitted by the light unit; and a control unit for controlling the display unit to display the region of the light reflector which reflects light photographed by the camera, and determining whether the radiation is aligned to the first region of the object based on whether the region of the light reflector is included in the shape of the first region.
US11065473B2	Methods and systems for checking alignment of components of a radiotherapy system A method of operating a radiotherapy system mounted on a gantry surrounding a magnetic resonance imaging system is provided, the radiotherapy system comprising a radiotherapy beam generator, and a radiotherapy imaging system, wherein the gantry is arranged to rotate the radiotherapy beam generator around the magnetic resonance imaging system. The method comprises obtaining a reference image, the reference image including a predetermined feature of the magnetic resonance imaging system located near the radiotherapy imaging system; rotating the gantry relative the magnetic resonance imaging system; obtaining a second image, the second image including the predetermined feature of the magnetic resonance imaging system located near the radiotherapy imaging system; and determining changes in the relative positions of the radiotherapy beam generator, the radiotherapy imaging system, and the magnetic resonance imaging system based on differences in the position of the predetermined feature in the reference image and in the further image.
US11065471B2	Systems and methods for automatic, customized radiation treatment plan generation for cancer Systems and methods for automatic, customized radiation treatment plan generation for cancer are disclosed. According to an aspect, a method includes receiving data indicating anatomy information of a patient and radiation beam characteristics of a radiation therapy system. Further, the method includes determining energy levels for application of radiation beams to the patient.
US11065470B2	Tissue sampling and catheter selection cancer treatment methods A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.
US11065466B2	Shock determination based on prior shocks A system for managing care of a person receiving emergency cardiac assistance is disclosed that includes one or more capacitors for delivering a defibrillating shock to a patient; one or more electronic ports for receiving signals from sensors for obtaining indications of an electrocardiogram (ECG) for the patient; a patient treatment module executable on one or more computer processors to provide a determination of a likelihood of success from delivering a future defibrillating shock to the person with the one or more capacitors, using (a) information about a prior defibrillating shock, and (b) a value that is a function of current ECG signals from the patient.
US11065464B2	Methods for wearable system A wearable system includes a support structure with optionally one or more electrodes in an unbiased state. Different sensor modules may monitor, for the long-term, different patient parameters such as the patient's motion, a physiological parameter, a patient sound etc., other than the patient's ECG. The sensor modules can be worn by the patient concurrently, or only one at a time as convenient, and may provide respective sensor signals. The system may determine from one or more of the available received signals whether a certain threshold has been reached, such as when the patient is having an actionable episode. If so, at least one electrode may become mechanically biased against the patient's body, for making good electrical contact. Then, an ECG reading may be taken and/or therapy may be administered.
US11065462B2	Wireless recharging system and method for flexible implantable subcutaneous medical device Subcutaneous implantable medical device (IMD) recharging system, including a flexible rechargeable subcutaneous IMD and a charger transmitter, the flexible rechargeable subcutaneous IMD implanted in a patient and including at least one receiver antenna and at least one rechargeable battery, the charger transmitter including at least one transmitter antenna and a modulator, the charger transmitter for providing electromagnetic (EM) radiation to the receiver antenna wirelessly for recharging the rechargeable battery, the transmitter antenna being encased in a structure for temporarily coupling the transmitter antenna to the skin of the patient and the modulator being for modulating the EM radiation and for simultaneously transmitting programming information to the flexible rechargeable subcutaneous IMD as modulated EM radiation.
US11065461B2	Implantable power adapter An apparatus includes a power adapter having a housing and a circuit at least partially disposed in the housing. The housing is configured to be coupled to an implantable device for disposition in a body. The circuit is configured to be electrically connected to a power circuit of the implantable device when the housing is coupled to the implantable electrical conductor. When the housing is coupled to the implantable electrical conductor and implanted in a body, the circuit is configured to (1) receive, transcutaneously from a power supply, a first energy, (2) convert the first energy to a second energy, and (3) transfer, to the implantable device, the second energy such that the second energy powers the implantable device.
US11065459B2	Implantable medical device with pressure sensor An implantable medical device (IMD) is configured with a pressure sensor. The IMD includes a housing and a diaphragm that is exposed to the environment outside of the housing. The diaphragm is configured to transmit a pressure from the environment outside of the housing to a piezoelectric membrane. In response, the piezoelectric membrane generates a voltage and/or a current, which is representative of a pressure change applied to the housing diaphragm. In some cases, only changes in pressure over time are used, not absolute or gauge pressures.
US11065456B2	Apparatus and method for implanting an implantable device In various examples, an apparatus is configured for subcutaneously inserting an implantable device within a patient. The apparatus includes a dilator portion including a dilator including a dilator length. The dilator portion is configured to separate tissue to create a subcutaneous pocket within the patient sized and shaped to accommodate an implantable device within the subcutaneous pocket. A sheath portion includes a sheath sized and shaped to accommodate the dilator within a sheath lumen. The sheath is configured to accommodate an antenna of the implantable device with the dilator removed from within the sheath. The sheath includes a sheath length that is at least substantially as long as an antenna length. The sheath is configured to separate to allow removal of the sheath around the implantable device to remove the sheath from and leave the implantable device within the subcutaneous pocket within the patient.
US11065453B2	Extra-cardiovascular cardiac pacing system An extra-cardiovascular medical device is configured to select a capacitor configuration from a capacitor array and deliver a low voltage, pacing pulse by discharging the selected capacitor configuration across an extra-cardiovascular pacing electrode vector. In some examples, the medical device is configured to determine the capacitor configuration based on a measured impedance of the extra-cardiovascular pacing electrode vector.
US11065449B2	Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters. Stimulation signals providing reduced power consumption with at least adequate symptomatic relief may be applied prior to moderate or significant power source depletion.
US11065445B2	Transcranial stimulation with real-time monitoring Closed-loop transcranial stimulation and monitoring is disclosed that includes generating a stimulation signal having a set of first oscillation parameters; applying the stimulation signal transcranially to a patient; monitoring the stimulation signal as applied to the patient; receiving a brain activity signal from the patient; generating a feedback signal based on the monitored stimulation signal as applied to the patient; and generating a modified activity signal by subtracting the feedback signal from the brain activity signal; determining one or more second oscillation parameters of the modified activity signal; and adjusting the set of first oscillation parameters of the stimulation signal based on the one or more second oscillation parameters of the modified activity signal. Closed-loop transcranial stimulation and monitoring is also disclosed in which the patient is engaged in a cognitive task.
US11065442B2	Implantable medical device which may be controlled from central station An implantable electrical stimulating device and system provides for a remote determination of the identity of the person in whom the stimulating device is implanted. The stimulating device may be a pacemaker, a defibrillator, another medical device or a non-medical device. The bases for the remote identification are (1) the comingling of (A) biologic identification information of the person linked to the stimulating device, and (B) information pertaining to a physiologic parameter (e.g. heart rate information) of that person, and (2) the modulation of the physiologic parameter by external information. Embodiments of the invention in which the stimulating device is external to the person are possible. By utilizing the apparatus providing for the remote identification of a person plus stimulating device, one aspect of secure communication—that based on reliable mutual identification of each participant in a communication—is achieved.
US11065441B2	Electrode fixation in interventional medical systems An implantable medical device assembly includes a mounting structure, an electrode protruding from a surface of the structure, between opposing sides thereof, and tissue-penetrating fixation tines, each extending from a corresponding shoulder of the structure surface, adjacent to the opposing sides. In a relaxed condition, each tine extends away from the surface and then bends toward a proximal end of the structure and back toward the surface. In an extended condition, each tine bends toward a distal end of the structure and extends along the corresponding shoulder. A holding member of a delivery tool has opposing sidewalls defining a cavity, wherein each sidewall includes a rail-like edge that fits in sliding engagement with a corresponding shoulder, to deform a corresponding tine into the extended condition, when an operator passes the assembly into the cavity. Applying a push force, to move the assembly back out form the cavity, releases the tines.
US11065439B1	Conforming modular neural interface system Disclosed herein are systems, devices, and methods for better conforming to biological tissue, reducing the temperature and irritation of tissue, modulating tissue, and/or wirelessly sending and receiving power through tissue. Devices can include panels movable with respect to each other to allow the body to move between a flattened and non-flattened state. Devices can include movable parts or structures that enable improved conformance to three-dimensional surfaces of tissue.
US11065428B2	Microneedle array with active ingredient Microneedle arrays for introducing an active ingredient through a skin surface of a subject can include a base layer, a plurality of microneedles projecting from the base layer, and an active ingredient. Each of the microneedles comprises an elongate body having a proximal portion and a distal portion, in which the proximal portion is attached to the base layer. Each of the microneedles comprises at least one dissolvable polymer. The active ingredient is incorporated in the elongate body, and the active ingredient is present only in the distal portion and at least internally in the distal portion.
US11065422B2	Devices, systems, and methods useful to engage tissue using suction and to perform medical procedures during suctional engagement Devices, systems, and methods useful to engage tissue using suction and to perform medical procedures during sectional engagement. The present disclosure includes disclosure of a tension apparatus, comprising an elongated portion; and a head portion at a distal end of the elongated portion, the head portion comprising one or more arms, whereby a suction lumen extending along the elongated portion and the one or more arms terminates at one or more suction openings at each of the one or more arms.
US11065418B1	Bladder storage anomaly assessment A method of assessing bladder storage anomalies via utilization of an indwelling urinary drainage catheter is provided. A urodynamic assessment assembly is provided, the assembly characterized by a pressure sensor for vesical pressure measurement, a processor/controller for receiving, processing and/or displaying select urodynamic patient parameters comprising sensed/monitored pressure data, and a catheter balloon adaptor for operably uniting the pressure sensor of the urodynamic assessment assembly to a balloon inflation valve of the indwelling urinary drainage catheter, the indwelling urinary drainage catheter operably linked with the urodynamic assessment assembly. Vesical pressure is sensed via the vesical pressure sensor during a bladder emptying event, the bladder emptying event characterized by an application of variable resistance to fluid flow from the bladder via the indwelling urinary drainage catheter with vesical pressure/outlet resistance/flow rate relationships established based upon sensed vesical pressure values.
US11065417B2	Method for manufacturing catheter and catheter manufactured by this manufacturing method A catheter manufacturing method includes positioning a shaft in a cavity of a mold. The shaft is an elongated tubular body configured to be inserted into a living body. The mold includes a first mold die and a second mold die that contact one another to define a closed space which is the cavity. The method includes injecting a molding material into the cavity from a gate at a position between the proximal end and the distal end of the shaft in the axial direction. The injecting position is offset from the center of the shaft in the transverse direction. The method includes molding a hub onto the shaft by solidifying the injected molding material in the cavity onto the outer surface of the shaft.
US11065416B2	Therapeutic device A therapeutic device that can diffuse essential oils, infuse frequency into liquids, emit frequency-driven lights, and produce solfeggio tones. The therapeutic device includes an enclosure, at least one oil-diffusing device, at least one frequency-infusing device, at least one frequency-tone generator, a first plurality of ambience lights, at least one vent, and a first controller. The enclosure is used to conceal and protect the electronic components. The at least one oil-diffusing device is used to diffuse fluids. The at least one frequency-infusing device is used to infuse frequency by vibration into fluids. The at least one frequency-tone generator is used to generate tones of different frequencies. The first plurality of ambience lights is used for aesthetic and therapeutic aspects. The at least one vent is used as an escape for the mist produced by the diffusion of the fluids. The first controller is used to manage the electronic components.
US11065412B2	Valsalva mask An interface for positive pressure therapy includes a mask assembly and a headgear assembly. The mask assembly comprises a mask seal that is adapted to underlie the nose. The mask seal extends up the lateral sides of the nose. The mask seal has a primary seal below the nose and a secondary seal alongside the nose.
US11065410B1	Dental appliance using airway dialation for treating covid related breathing disorders A molded breathing appliance for supporting a nasal oxygen tube having an upper bite rim, a lower bite rim, a moldable material disposed within the upper bite rim and lower bite rim for conforming to a patient's maxillary bite impression and mandibular bite impression, respectively, an L-shaped member extending outwardly perpendicular to the upper bite rim, and a transverse support disposed on the L-shaped member and configured with a plurality of sets of oxygen tube finger clamps to retain a nasal oxygen tube in proximity with a patient's nostrils.
US11065407B2	Resuscitation bag Resuscitation apparatuses and methods for assisted ventilation are described herein. The apparatuses may include functional elements that allow the manual delivery of a prescribed volume to an adult or an infant lung. Furthermore, the apparatuses may inform and assure an emergency worker that an appropriate volume is being delivered and therefore lessen the possibility of barotrauma from over-delivery, or ventilatory distress from under-delivery. In some embodiments, the apparatuses include biomechanical and ergonomic functional elements that allow an adult hand to hold it in place during operation, while at the same time, allowing the user to actuate the apparatus to deliver only the necessary amount of volume suitable for an infant lung. In other embodiments, a volume-controlled design is applied to pediatric and adult resuscitation.
US11065405B2	Electronic cigarette, and method of cleaning an electronic cigarette An electronic cigarette includes a ceramic heating element having a current conducting heating member on and/or in a body of ceramic material which is impenetrable to the liquid; a liquid delivery member to deliver liquid from a liquid storage to the heating element; a battery; and an electric circuit for electrically connecting the heating element to the battery. The body of ceramic material is to contact or be in close proximity to the liquid delivery member, to vaporize the liquid when the ceramic heating element produces heat. The electronic cigarette further includes a cartomizer part, having the liquid storage and the liquid delivery member, and a battery holding part, having the battery, the ceramic heating element, and the electric circuit. In an assembled state, the cartomizer part and the battery holding part are assembled. In a disassembled state, the cartomizer part and the battery holding part are separated.
US11065399B2	Nebulizer vibrating aperture plate drive frequency control and monitoring A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
US11065397B2	Inhalation device, inhalation device set, and nozzle plate therefor An inhalation device including a housing, which encloses a liquid reservoir in which the liquid is stored before discharge, and an applicator head with a nebulization chamber and an applicator piece connected thereto, wherein the applicator piece is designed either as a mouthpiece, to be received in the mouth of a patient, or as an inhalation mask, to sealingly cover the mouth, the nose, or the mouth and the nose. The inhalation device furthermore has a discharge channel which connects the liquid reservoir to the applicator head. The inhalation device includes at the end of the discharge channel a nozzle plate with a large number of nozzle openings which serve to generate an inhalation mist and through which the liquid from the liquid reservoir is conveyed into the nebulization chamber.
US11065395B2	Contact trigger release needle guard with elastic spring A needle guard device mountable to a pre-filled syringe in its ready-to-fill state. The device includes a device shield interconnected to a lock collar with flexible member and biased to move relative to the lock collar. The lock collar interfaces with the syringe neck to attach the device to the syringe. As the device shield moves proximally, rotation arms of the lock collar interact with angled cutouts in the device shield, causing the device shield to rotate relative to the lock collar and disengaging one or more keys on the device shield from one or more keyways in the lock collar triggering the device shield to move from a first configuration in which the device shield is retractable to expose a syringe sharp to a second configuration in which the device shield is fixedly positioned to cover the syringe sharp.
US11065394B2	Syringe with retractable needle The invention relates to a syringe with a retractable needle comprising a barrel (2) having a nozzle (19) integrated in a male Luer adapter element (26); a piston (3) slidably arranged in the barrel (2) and coupled to a sealing element (16), said sealing element (16) having a central channel (20); a needle assembly comprising a needle (4), a needle holder (6) and a female Luer adapter element (7); a spring assembly arranged in the piston (3) comprising a spring sleeve (12), a spring (13) mounted on the spring sleeve (12), a spring tensioning element (14) located on the spring sleeve (12) and held in position by the piston wall, and a plunger (15) mounted within the spring sleeve; and a piston cap (10); said piston (3) being coupled to the sealing element (16) by means of the spring tensioning element (14); said spring sleeve (12) being held in position within the piston (3) by a ring element (18) protruding from the inner wall of the piston (3) and supporting the proximal end of the spring sleeve (12), the spring sleeve extending into the channel (20) of the sealing element (16) to the distal end thereof; said spring sleeve (12) comprising at its distal end a circular protrusion (21) on the inside designed to engage a circular recess (22) at the proximal end of the needle holder (6); wherein the piston (3) comprises a holding ring (11) on its inner surface designed to engage with an outer flange (17) of the spring sleeve (12) after actuation of the spring (13).
US11065387B2	Activation mechanism for a medicament delivery device and a medicament delivery device using the activation mechanism An activation mechanism for a medicament delivery device is provided having a housing elongated along a generally longitudinal axis, a spring-biased drive member, a locking unit, movable from a locked position, preventing longitudinal movement of said drive member, to an unlocked position, a first activation member movable relative to the housing; a second activation member movable relative to the housing, and wherein the locking unit comprises a key member, movable relative to the locking unit, wherein the first activation member and the second activation member are configured to move the locking unit from the locked position to the unlocked position, wherein upon actuation, the first activation member and the second activation member cooperate in interacting with the key member to move the key member to the cooperating position and to move the locking unit from the locked position to the unlocked position.
US11065385B2	Fluid bolus detection The present disclosure provides systems that include a flow probe that senses fluid flow or mass flow of fluid delivery to a patient. Based at least in part on the sensed fluid or mass flow, the flow probe provides flow-related data (e.g., volume or mass flow rate) that the system uses to derive a volume of fluid being delivered. The fluid can be delivered from an IV bag, another in-line port, or a combination of the two. The disclosed systems provide fluid volume and/or fluid rate for display to a clinician and an informative understanding of what volume of fluid/mass a patient has received.
US11065384B2	Administration set detection and authentication using CAM profiles An administration set for an infusion pump includes a free-flow prevention device having a movable plunger that includes a cam surface defining an uneven profile along a direction of movement of the plunger, wherein the shape of the cam surface profile indicates the administration set is authorized for use with the infusion pump and may further indicate the specific type of administration set. A sensor in the infusion pump senses movement of the plunger as a platen of the infusion pump is latched and generates a profile signal in the time domain representative of the cam surface profile. A processor evaluates the profile signal and controls operation of the pump to protect a patient from improper loading of an administration set, use of an unauthorized administration set, and/or use of an invalid type of administration set for a chosen infusion protocol.
US11065383B2	Connector and transfusion set A connector provided with a housing which defines an insertion section into which a male connector is inserted from the outside and a flow path communicating with the insertion section and an elastic valve body which has a slit and blocks the insertion section. The housing includes a tip receiving section formed on an inner wall defining the flow path, the tip receiving section receiving a tip of the male connector inserted through the slit of the elastic valve body. The tip receiving section is formed on only a part of the inner wall in a cross section that is perpendicular to an insertion direction of the male connector and includes at least a part of the tip receiving section.
US11065382B2	Apparatus to inject fluids into bone marrow and other target sites The present disclosure relates to an apparatus for providing access to bone marrow and delivering a quantity of fluid to an intraosseous space. The apparatus may include a driver having a housing and a drive shaft, and a plunger operating and cartridge drive mechanism for releasably retaining a portion of a cartridge assembly having a plunger assembly. A plunger operating assembly may be disposed within a longitudinal bore of the plunger operating and cartridge drive mechanism. The plunger operating assembly may include a plunger barrel having a chamber configured to receive a portion of the plunger assembly of the cartridge assembly. The apparatus may also include a drive housing for transmitting rotational forces from the drive shaft to the cartridge assembly.
US11065379B2	Method and system for controlled hyperthermia Methods and for treatment of cancer and other diseases including complications from late stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed. The method can also be effective in treating rheumatoid arthritis, scleroderma, hepatitis, sepsis, the Epstein-Barr virus, and patients with life threatening complications from other viruses, including the COVID-19 virus. A method for removing viruses from the blood supply in an external circuit is also presented.
US11065378B2	Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood The present invention relates to a method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from mammalian blood/use of a device comprising a carbohydrate immobilized on a solid substrate, said carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, for extracorporeal removal of said pathogenic microbe, inflammatory cell or inflammatory protein from mammalian blood/use of a carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, wherein said carbohydrate is immobilized on a solid substrate, in the preparation of a device for treatment of a condition caused or aggravated by said pathogenic microbe, inflammatory cell or inflammatory protein and a method for treatment of a mammalian subject suffering from a condition caused or aggravated by a pathogenic microbe, an inflammatory cell or an inflammatory protein.
US11065375B2	Blood oxygenator A blood oxygenator is disclosed comprising a housing, a blood inlet, a blood outlet, a spiral volute, a gas inlet, an oxygenator fiber bundle, and a gas outlet. The housing encloses the fiber bundle and provides the structure for the blood flow path and connectors. The fiber bundle comprises gas-exchange membranes which transfer oxygen to the blood and remove carbon dioxide when the blood flows across the membranes. The spiral volute guides the blood to flow through the fiber bundle. A gas flow chamber receives sweep gas containing oxygen and distributes the sweep gas into the fiber membranes, which gas is then exchanged with the blood being oxygenated.
US11065374B2	Renal failure therapy system and method of cleaning using citric acid A renal failure therapy system (10a, 10b) includes a dialysis fluid circuit (30) including a dialysis fluid pump (54, 58); a source (86, 90) of physiological cleaning, disinfecting, and/or decalcifying substance in fluid communication with the dialysis fluid circuit; a source (22) of purified water in fluid communication with the dialysis fluid circuit; and a logic implementer (20) in operable communication with the dialysis fluid pump (54,58), the logic implementer (20) causing the physiological cleaning, disinfecting, and/or decalcifying substance from its source (86, 90) to be added to purified water from the purified water source (22) to form a mixture and to circulate the mixture within the dialysis fluid circuit using the dialysis fluid pump (54,58) to at least one of clean, disinfect or decalcify at least a portion of the dialysis fluid circuit (30) without a subsequent rinse.
US11065373B2	Water preparation system for dialysis treatments The invention relates to a water treatment system (1) for dialysis treatments, wherein the water treatment system (1) comprises a permeate circuit with a reverse osmosis system (RO) and at least one tap (ES1, 2 . . . N) for permeate, whereby the reverse osmosis system (RO) is fed by the reflux of the at least one tap (ES1, 2 . . . N) for dialysis treatments and/or a raw water inflow (RZ), whereby the water treatment system further comprises a heat exchanger (WT), whereby a primary circuit (PK) of the heat exchanger (WT) is connected with a buffer tank (PT) for storing thermal energy, whereby a second circuit (SK) of the heat exchanger (WT) is integrated into the permeate circuit, whereby heat is transferred in a controlled manner from the buffer tank (PT) via the heat exchanger (WT) to permeate in the permeate circuit.
US11065370B2	Device for drainage, in particular for the drainage of a chronic subdural hematoma A device for drainage includes a tubular reservoir having a tubular pliable wall, a rigid cover, and a rigid bottom, and also includes at least one spring which applies a force that presses the cover and the bottom apart, wherein the cover is movable in the direction of the bottom in order to place the spring into a start position. One or more magnets are configured such that the magnets apply an additional force on the reservoir in such a way that a resulting force pressing the cover and the bottom apart is substantially constant across as the spring is deflected.
US11065366B2	Method for producing a fibrin-based bioartificial, primarily acellular construct, and the construct itself The invention relates to a method for producing a bioartificial and primarily acellular fibrin-based construct, wherein a mixture of cell-free compositions containing fibrinogen and thrombin is applied to a surface and subsequently pressurised. An additional aspect of the invention is directed to such fibrin-based bioartificial acellular constructs obtained according to the invention, with improved biomechanical properties, as well as to the use of same in the field of implantology, cartilage replacement or tissue replacement.
US11065365B2	Preparation and/or formulation of proteins cross-linked with polysaccharides Therapeutic compositions and/or formulations are provided, comprising: at least one cross-linked protein matrix, wherein the at least one cross-linked protein matrix comprises at least one protein residue and at least one saccharide-containing residue, and methods of producing the same. The cross-linked protein matrix may be derived from cross-linking a full length or substantially full length protein, such as tropoelastin, elastin, albumin, collagen, collagen monomers, immunoglobulins, insulin, and/or derivatives or combinations thereof, with a saccharide containing cross-linking agent, such as a polysaccharide cross-linking agent derived from, for example, hyaluronic acid or a cellulose derivative. The therapeutic compositions may be administered topically or by injection. The present disclosure also provides methods, systems, and/or kits for the preparation and/or formulation of the compositions disclosed herein.
US11065362B2	Viscoelastic hydrogels with fast stress relaxation Provided are fast relaxing hydrogels that are useful for regulating cell behavior and enhancing tissue regeneration, e.g., bone regeneration.
US11065358B2	Air-blade, silencer and separator apparatus and method Silencing and separation in a cold-air, essential-oil, diffuser apparatus and method pass flow through a channel having comparatively high aspect ratios of length to thickness and width to thickness. Curved, tapered, non-parallel, and quasi random surfaces reduce probability and power of resonant frequencies. Offsetting flow through a channel is followed by impingement against an obstructing surface, redirection elsewhere within a drift (separation) chamber, and exiting through a smaller, and differently oriented exit port. Silencing is improved by changes of cross-sectional area creating high-pass and low pass acoustic filters, changes of direction, and absorption of acoustic energy in fluid-droplet-laden air.
US11065357B2	Water dispersible fragranced film and use thereof Fragranced films containing a water soluble a/o water dispersible polyvinyl alcohol polymer are disclosed. Uses of the fragranced films in providing a fragrance benefit and/or in controlling malodours is also disclosed, including when used in conjunction with lavatory appliances, dishwashing machines and in laundry washing machines.
US11065349B2	18F labeled BODIPY dye and its derivatives for PET imaging of heart perfusion and others This invention provides a class of dual mode imaging tracer capable of acting both as a fluorescent imaging tracer and a positron emission tomography imaging tracer. Tracers in accordance with this invention generally have a fluorescent core with a boron-fluoride element embedded therein. Exemplary embodiments of the tracer include 18F-labeled BODIPY compounds and derivative thereof. Also provided are tracer kits containing a sterile formulation of a BODIPY dye either in a radio-labeled or pre-labeled state, and methods for imaging heart perfusion using the 18F-labeled dual mode tracers.
US11065347B2	Methods for the treatment of Danon disease and other disorders of autophagy This disclosure provides gene therapy vectors comprising a polynucleotide encoding one or more isoforms of lysosome-associated membrane protein 2 (LAMP-2), and methods of using such gene therapy vectors for the treatment of Danon disease and other autophagy disorders.
US11065346B2	RNA for use in the treatment of ligament or tendon lesions Described is a liquid composition containing naked RNA, such as mRNA encoding a polypeptide, for use in the treatment or prevention of ligament or tendon lesions as well as a method for treating ligament or tendon lesions comprising the administration of a liquid composition containing naked RNA, such as mRNA encoding a polypeptide, which is beneficial in the process of healing the ligament or tendon lesions.
US11065345B2	Methods for assembling scavenging particles The disclosure provides, methods for preparing scavenging particles, as well as methods for attaching capture agents to the particles. The disclosure further provides compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.
US11065344B2	Nanocluster capped mesoporous nanoparticles, methods of making and use Embodiments of the present disclosure describe a conjugate comprising a mesoporous nanoparticle having a plurality of pores, wherein the mesoporous nanoparticle is positively charged, wherein an active agent is disposed in the pore; and a plurality of metal nanoclusters, wherein the metal nanocluster has a negative charge, wherein a gate agent is attached to the metal nanocluster. Embodiments of the present disclosure also describe a method of using a conjugate comprising exposing a conjugate to microbes sufficient to release an active agent and treating the microbes with the released active agent. Embodiments of the present disclosure further describe a method of using a conjugate comprising exposing a conjugate to microbes and detecting a presence of the microbes.
US11065343B2	Compound bearing beta-galactoside-introduced self-immolative linker The present invention relates to a compound bearing a self-immolative linker having β-galactoside-introduced thereto. In a compound bearing a β-galactoside-introduced self-immolative linker according to the present invention, particularly, the self-immolative linker may form a glycosidic bond with a protein (e.g., an oligopeptide, polypeptide, an antibody, etc.) or ligand which has specific affinity for a desired target or with an active agent (e.g., a drug, a toxin, a ligand, a detection probe, etc.), which has a specific function or activity so as to allow the selective release of the active agent within a target cell.
US11065341B2	DE-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy The present invention generally provides compositions methods and composition relating to the diagnosis and/or treatment of cancers having a cell surface de-N-acetylated sialic acid antigen, e.g., an at least partially de-N-acetylated ganglioside and/or a de-N-acetylated sialic acid-modified cell surface protein.
US11065340B2	Polyoxazoline antibody drug conjugates In the present disclosure, polymer conjugates, including polymer-antibody-drug conjugates (polymer ADCs) are described, as well as the use of such conjugates to treat human disease. The polymer conjugates can contain a large number of polymer-bound agents, thus effectively increasing the drug antibody ration (DAR) of the antibody significantly beyond the currently available technology. This may be of particular importance when antibodies to low density antigens are used as target antibodies. The described polymer-ADCs have improved pharmacokinetics and solubility relative to traditional ADCs. The linker between agent and the polymer can be tailored to provide release of toxin at the desired site and under the desired conditions within the tumor. An additional feature of the polymer-ADCs of the current disclosure is that a purification moiety can be attached to the polymer backbone to provide ease of purification of the polymer-ADCs.
US11065339B2	FAP-activated proteasome inhibitors for treating solid tumors Disclosed are proteasome inhibitors, fibroblast activation protein (FAP)-activated prodrugs of proteasome inhibitors, and pharmaceutically acceptable salts of the inhibitors and prodrugs. Also disclosed are related pharmaceutical compositions, and methods of using the inhibitors and prodrugs and compositions thereof, for example, in treating cancer or other cell proliferative diseases. In vitro and in vivo methods of quantifying the expression of FAP in a biopsy sample and a mammal, respectively, are also disclosed.
US11065336B2	Conjugates for targeting and clearing aggregates In some embodiments, the disclosure provides for a conjugate comprising: a) a peptide that competes with an Fc fragment of an IgG for binding to an Fc receptor; and b) a targeting moiety that targets molecular aggregates. In some embodiments, the disclosure provides for methods of using the conjugates for treating a disease or disorder associated with aggregate formation.
US11065329B2	Human herpesvirus immunotherapy An isolated protein comprises respective amino acid sequences of each of a plurality of CTL epitopes from two or more different herpesvirus antigens and further comprises an intervening amino acid or amino acid sequence between at least two of said CTL epitopes comprising proteasome liberation amino acids or amino acid sequences and, optionally, Transporter Associated with Antigen Processing recognition motifs. The isolated protein is capable of rapidly expanding human cytotoxic T lymphocytes (CTL) in vitro and eliciting a CTL immune response in vivo upon administration to an animal as an exogenous protein. Typically, the isolated protein comprises no more than twenty (20) CTL epitopes derived from cytomegalovirus and/or Epstein-Barr virus antigens.
US11065319B2	Methods for diagnosing and reducing incidences of cardiac allograft rejection Methods and products for diagnosing, treating and/or delaying onset of chronic allograft rejection, including cardiac allograft vasculopathy. In an exemplary embodiment of a noninvasive method of screening a cardiac allograft recipient for being at-risk for developing cardiac allograft vasculopathy of the present disclosure, the method comprises the steps of withdrawing at least one biological sample from a cardiac allograft recipient; and analyzing the at least one biological sample for one or more biomarkers indicative of the presence of fibrin deposits within the cardiac allograft microvasculature; wherein detection of the one or more biomarkers indicates that the cardiac allograft recipient is at-risk for or developing cardiac allograft vasculopathy.
US11065318B2	Yeast-MUC1 immunotherapeutic compositions and uses thereof Disclosed are yeast-based immunotherapeutic compositions comprising mucin-1 (MUC1), as well as methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of mucin-1 (MUC1).
US11065311B2	Retroviral vector with mini-promoter cassette This disclosure provides a retroviral replicating vector for gene delivery comprising a therapeutic cassette containing at least one mini-promoter linked to a gene to be expressed.
US11065307B2	Therapeutic fusion protein comprising an alpha-n-acetylglucosaminidase and a lysosomal targeting moiety Among other things, the present invention provides methods and compositions of treating Sanfilippo syndrome type B (Sanfilippo B) by, e.g., intrathecal (IT) administration of a Naglu protein. A suitable Naglu protein can be a recombinant, gene-activated or natural protein. In some embodiments, a suitable Naglu protein is a recombinant Naglu protein. In some embodiments, a recombinant Naglu protein is a fusion protein containing a Naglu domain and a lysosomal targeting moiety. In some embodiments, the lysosomal targeting domain is an IGF-II moiety.
US11065306B2	Methods for treating hypophosphatasia in children The disclosure features methods for treating hypophosphatasia (HPP) in a patient (e.g., a child having HPP) exhibiting physical impairments, disability in activities of daily living (ADL), pain, and/or delayed motor development by administering a soluble alkaline phosphatase (sALP) to the patient.
US11065304B2	Peptide pharmaceuticals for insulin resistance Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
US11065301B2	Pharmaceutical composition for ameliorating the symptoms and disease of the respiratory infection caused by human metapneumovirus (HMPV), which comprises at least one agent that neutralizes the function of TSLP and/or TSLPR and/or OX40L and/or CD177 molecules, and a pharmaceutically acceptable excipient, and use thereof The present invention relates to a pharmaceutical composition for ameliorating the symptoms and disease of the respiratory infection caused by human Metapneumovirus (hMPV), which comprises at least one agent that neutralizes the function of TSLP and/or TSLPR and/or OX40L and/or CD177 molecules, and a pharmaceutically acceptable excipient, wherein the agent is selected from monoclonal antibodies, biological or synthetic molecules. More specifically, the neutralizing agents are humanized anti-TSLP, anti-TSLPR, anti-OX40L and anti-CD177 monoclonal antibodies. The use of said composition for preparing a medicament for treating or ameliorating the symptoms and disease of patients infected with human Metapneumovirus (hMPV) is also described.
US11065299B2	Compositions and methods for modulation of immune response Provided herein are compositions and methods for modulation of immune response via PYRIN domain-only proteins POP1 and/or POP3. In particular, POP1 and/or POP3 are inhibited to enhance an immune response (e.g., to treat or prevent infection), or POP1 and/or POP3 are administered or activated to reduce an immune response (e.g., to treat or prevent autoimmune or inflammatory disease).
US11065298B1	Compositions and methods for treating or preventing viral infections Compositions and methods disclosed herein may be used for treating or preventing viral infections. The compositions may be administered orally to subjects in need of preventative or therapeutic treatment and/or the compositions may be used to disinfect surfaces in order to prevent or limit the spread of disease through surface contact.
US11065296B2	Antimicrobial peptide, its analog and use In various embodiments, a pharmaceutical composition comprising an effective amount of a peptide having the amino acid sequence represented by Formula (I) or an analog thereof, and a pharmaceutically tolerable excipient is described. In some embodiments, the analog of the peptide of Formula (I), comprises the peptide sequence of Formula (I) wherein one or more of the amino acids residues are modified by a) C-terminal modification; b) D-amino acid substitution; and/or c) deletion of one or more amino acid residues. A method of inhibiting the growth of a microorganism comprising contacting the microorganism in a medium with an effective amount of the peptide of Formula (I) or an analog thereof is also described, as are similar methods of treating a disease or disorder associated with microbial activity in a subject by administering an effective amount of a peptide of Formula (I) or an analog thereof and a pharmaceutically tolerable excipient to the subject.
US11065292B2	Feijoa fruit extract The invention relates to a feijoa fruit extract. In particular the invention relates to therapeutic uses of a feijoa fruit extract, processes for preparing the extract, and compositions comprising the extract. The feijoa fruit extract of the invention can be used in the treatment and prevention of rheumatoid arthritis and Type-2 diabetes.
US11065284B2	Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them The present disclosure provides for acid-resistant capsules comprising compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon. Compositions of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection.
US11065282B2	Coral composite extract, composition including the same and method of producing the same The present invention relates to a coral composite extract, a composition including the same and a method of producing the same. The coral composite extract includes at least two briarane-type diterpenoid compounds from corals of Briareum violaceum, B. excavatum and B. stechei, thereby being applied as an effective ingredient of a skin external use composition, a cosmetic composition and a medicinal composition.
US11065279B2	Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11065275B2	Cross-linking agents and associated methods An ophthalmic composition or dosage form can include a therapeutically effective amount of a cross-linking agent and a pharmaceutically acceptable carrier. The composition or dosage form can be used to treat an ophthalmic condition by administering a therapeutically effective amount of the composition to an eye of a subject during a treatment period.
US11065267B2	Lysophosphatidylcholine compositions The present invention provides marine lysophosphatidylcholine compositions for use in pharmaceuticals, nutraceuticals and functional foods, as well as methods for making marine lysophosphatidylcholine compositions.
US11065266B2	Method of treating melanoma using an inhibitor of an atypical protein kinase C The invention pertains to a method of treating melanoma by administering to a subject in need thereof, a composition comprising a therapeutically effective amount of an inhibitor of PKC-ζ and/or PKC-ι. Non-limiting examples of an inhibitor of PKC-ζ and/or PKC-ι include ICA-1 and ACPD. The invention also provides PKC-ζ and/or PKC-ι as biomarkers for identifying a melanoma in a subject as likely to be responsive or non-responsive to a therapy using an inhibitor of PKC-ζ and/or PKC-ι. Accordingly, a method of identifying a subject having a melanoma as being responsive or non-responsive to a melanoma therapy with an inhibitor of PKC-ζ and/or PKC-ι based on the levels and/or activity of PKC-ζ and/or PKC-ι mRNA or protein in the melanoma cells from the subject are also provided.
US11065265B2	Compositions of fosaprepitant and methods of preparation The present application and its embodiments teach stable compositions of fosaprepitant or a pharmaceutically acceptable salt thereof with such compositions lacking polysorbate 80 and containing dual functional excipients of hydrolysis inhibition and solubility enhancement. Further described are methods of preparation of such compositions. Among other advantages of contemplated compositions, fosaprepitant hydrolysis degradation is kept low and the compositions maintain physically and chemically stable for prolonged period.
US11065253B2	Arylquinazolines The invention relates to novel compounds of the formula (I) which can be used for the inhibition of serine-threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation.
US11065252B2	Treatment of rosacea with P38 and Erk kinase pathway inhibitors A treatment for ocular rosacea using p38 and Erk kinase pathway inhibitors, which are believed to block the initial reaction to rosacea triggers and thus make it possible to prevent or minimize the skin reaction. The treatment is premised on a careful analysis of the alteration of cell-signaling pathways that facilitate the development of rosacea, which led to the identification of discrete targets for highly specific therapeutic intervention in the management of rosacea.
US11065249B2	Diacylglycerol acyl transferase 2 inhibitor Described herein are compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are defined herein, their use as diacylglycerol acyltransferase 2 (DGAT2) inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, NASH.
US11065246B2	Glucomannan containing pharmaceutical compositions with extended release and abuse deterrent properties A pharmaceutical composition comprising at least one active pharmaceutical ingredient (API) or a pharmaceutically acceptable salt thereof, a glucomannan, a first polyalkylene oxide having an average molecular weight of no more than 300,000, and a second polyalkylene oxide having an average molecular weight of at least 1,000,000 and methods of making. The pharmaceutical composition provides extended release of the API and has abuse deterrent features.
US11065242B2	Antibiotic solution and method of injection to prevent ophthalmic infections A method of preventing post-operative endophthalmitis involves injecting a colored antibiotic solution into the anterior segment of the eye during surgery, the antibiotic solution having moxifloxacin, cefuroxime, vancomycin, or some combination thereof, and the coloring agent being preferably a cobalamin (e.g., cyanocobalamin).
US11065240B2	Drug combinations to treat multiple myeloma This invention relates to the combination of a C-Met inhibitor and a proteasome inhibitor to treat cancer, particularly multiple myeloma.
US11065239B2	Use of EZH2 inhibitor combined with BTK inhibitor in preparing drug for treating tumor This application describes a use of an EZH2 inhibitor combined with a BTK inhibitor in preparing a drug for treating a tumor is described.
US11065233B2	Estrogen receptor modulators Compounds of Formula (I) are estrogen receptor alpha modulators, where the variables in Formula (I) are described in the disclosure. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions that are estrogen receptor alpha dependent and/or estrogen receptor alpha mediated, including conditions characterized by excessive cellular proliferation, such as breast cancer.
US11065232B2	Dihydrotetrabenazine for the treatment of anxiety and psychoses This invention relates to pharmaceutical compositions containing (−)-β-dihydrotetrabenazine, processes for making them and their therapeutic uses.
US11065231B2	Compounds and methods for the targeted degradation of interleukin-1 receptor- associated kinase 4 polypeptides The present disclosure relates to bifunctional compounds, which find utility as modulators of Interleukin-1 Receptor-Associated Kinase 4 (IRAK-4); the target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a Von Hppel-Lindau, cereblon, ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.
US11065230B2	Methods and pharmaceutical compositions for the treatment of systemic mastocytosis The present invention relates to methods and pharmaceutical compositions for the treatment of systemic mastocytosis. The inventors showed the effect of KPT-251 treatment on SCF-dependent human Mast cell (MC) line without KIT mutation (WT ROSA) and on two factor-independent MC lines with KIT mutations : ROSA Δ 417-419 insY and ROSA D816V. KPT is a Selective Inhibitor of Nuclear Export (SINE) that specifically inhibits the activity of the exportin-1 (XPO1). KPT-251 treatment induces minimal toxicity in non-cancerous hematopoietic cells both in vitro and in vivo. In particular, the present invention relates a method of treating systemic mastocytosis in patient in need thereof comprising administering to the patient a therapeutically effective amount of a XPO1 inhibitor.
US11065223B2	Antimicrobial compositions and uses thereof In some aspects, provided herein are antimicrobial compositions comprising partially esterified polygalacturonic acid and certain fatty acids (e.g., caprylic acid). In some embodiments, the antimicrobial composition may be administered (e.g., topically or orally) to a subject, such as a human patient to treat an infection (e.g., an infection comprising a biofilm). In some aspects, improved catheters are provided.
US11065214B1	Combination therapies with disulfiram Disclosed herein are compositions and methods for increasing lifespan, for preventing or treating a disease including an aging-related disorder, for reducing a symptom of aging, and/or boosting an immune system in a mammal. Also disclosed herein are compositions and methods for improving effectiveness of a vaccine in a mammal. The compositions comprise, at least, a therapeutically effective amount of disulfiram and one or more additional ingredients.
US11065212B2	Methods and compositions for preventing or treating calciphylaxis The invention provides methods and compositions for preventing or treating (e.g., slowing the progression of, arresting, and/or reversing) calciphylaxis in a subject in need thereof and, more particularly, the invention relates to methods of using menaquinone-7 (MK-7) and/or menaquinol-7 (MKH2-7) for preventing or treating calciphylaxis in a subject with one or more of the following: diabetes, chronic kidney disease, end stage renal failure, and COPD or a subject undergoing hemodialysis and/or receiving anticoagulant therapy and/or statin therapy.
US11065210B2	Reduction of adipose tissue Described herein, inter alia, are compositions, formulations, methods, and systems for reducing regional fat deposits and treating fat-related conditions.
US11065198B2	Dispersible compositions The present invention is concerned with dispersible compositions comprising rilpivirine or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. Such compositions are useful in the treatment of HIV infection and their dispersibility properties lend themselves to be useful in particular amongst the pediatric or geriatric population.
US11065194B2	Cosmetic use of extracts of Salvia miltiorrhiza roots, special extracts of Salvia miltiorrhiza roots and cosmetic compositions containing such extracts Methods in which an extract of Salvia miltiorrhiza roots is applied to the skin for a soothing cosmetic topical treatment. The invention also concerns a particular extract of Salvia miltiorrhiza roots, as well as compositions containing this extract and a cosmetic treatment method providing a soothing effect to the skin.
US11065192B2	Mascara compositions including vinylpyrrolidone homopolymer and an acrylic film-forming polymer A mascara composition includes a film-forming polymer portion. The film-forming polymer portion is stabilized in a vehicle that includes water. The film-forming polymer portion includes a high molecular weight vinylpyrrolidone homopolymer and an acrylic polymer having a glass transition temperature of 65° C. or more. The mascara composition includes at least about 10 percent by weight of the vinylpyrrolidone homopolymer and is substantially free of wax. Methods of applying makeup to the eyelashes are also provided.
US11065191B2	Method for thickening a cosmetic formulation using an alkali swellable emulsion of a polymer with amps and which is rich in acrylic acid Process for thickening a composition, through the use of a direct emulsion in water, which is alkali-swellable, of a polymer of the ASE or HASE type, which is both rich in acrylic acid and which has a certain quantity of AMPS. The use of such emulsions simultaneously allows there to be no obligation to use surfactants and organic solvents other than water, and allows the thickening phenomenon to be activated for pHs of less than 7: this latter characteristic is particularly advantageous for formulations intended to be used in contact with skin.
US11065190B2	Cosmetic composition comprising solubilized pigment and method for preparing the same One aspect of the present disclosure is a cosmetic composition containing a solubilized pigment and a method for preparing the same. More specifically, the cosmetic composition containing the solubilized pigment may be prepared through a process of dissolving a pigment in an aqueous phase by dispersing the pigment in the aqueous phase using a pigment dispersing thickener and stabilizing by further increasing the viscosity using a stabilizing thickener. Since the solubilized pigment exhibits dyeing properties similar to dyes, it can be widely applied to various cosmetic compositions.
US11065188B2	Applications and formulations of optimized, modified human embryonic fertility culture media with biguanides and/or functional equivalents A dermatological preparation comprises an optimized, modified human embryonic fertility culture media with biguanides and/or functional equivalents and the use of said preparation for skin care, hair care, or body care, or dental procedures, or for regenerative medicine such as promoting wound or bone healing. The preparation is formulated to target the hypoxic microenvironment niches of the skin tissue in combination with optimal concentration of nutrients, ions and minerals; to stimulate existing stem cells to trigger the capacity of stem cells to divide and renew and differentiate into specialized cells; and to stimulate molecular and physiological processes, e.g., autophagy, to replenish the substrate pool through the recycling of organelles and the recycling of old damaged proteins and countering free-radical damage to promote anti-aging.
US11065187B2	Particle bound photosensitizer molecule with reduced toxicity A method for forming a photosensitizer product that is resistant to absorption by living tissue that may include binding a photosensitizer compound with an oxide-containing particle to provide the photosensitizer derivative having a microscale size, and mixing the photosensitizer derivative into a lotion. The microscale size of the photosensitizer derivative obstructs absorption by cell tissue.
US11065184B2	Oil-in-water emulsion for making up and caring for the lips The invention relates to an oil-in-water emulsion for making up or caring for the lips. This emulsion contains a high proportion of glossy oils and is very fluid while remaining stable. This emulsion contains from 35% to 60% by weight of a mixture of oils, at least 25% by weight of water and from 0.01% to 20% of coloring material, everything being stabilized by the combination of a first polyethylene glycol ether of stearyl alcohol comprising from 2 to 5 oxyethylene units, a second polyethylene glycol ether of stearyl alcohol comprising from 15 to 25 oxyethylene units, and of a copolymer of acrylamido-2-methylpropane sulfonate and of hydroxyethyl acrylate.
US11065183B2	Curable composition Provided is a curable composition comprising a polymerizable monomer (A); spherical particles (B) having an average primary-particle diameter in a range of 230 nm to 1,000 nm; and a polymerization initiator (C), in which 90% or more of individual particles constituting the spherical particles (B) lies in a range of ±5% based on the average primary-particle diameter, and the refractive index of the spherical particles (B) is larger than the refractive index of a polymer of the polymerizable monomer (A). When a 1 mm-thick cured product is formed from the curable composition and the Y value (Yb) of the colored light of the cured product on a black background and the Y value (Yw) of the colored light of the cured product on a white background are each measured using a color difference meter, the ratio therebetween, Yb/Yw, being within a range of 0.2 to 0.5.
US11065182B2	Resin composite and restoration containing azole-functionalized silica A resin composite containing azole-functionalized silica nanoparticles. The resin composite further includes a polymerizable monomer and a polymerization initiator system. A dental restoration fabricated by curing the resin composite is also specified.
US11065179B2	Therapeutic pool flotation device and therapeutic method of use thereof A therapeutic flotation device and a therapeutic method of use thereof is disclosed. The device includes a plurality of buoyant float elements and a member (an elongated web strap) that couples each of the buoyant float elements such that the buoyant float elements are serially aligned along the member. A first end of the member is secured to a second end of the member. A mating mechanism, such as a buckle, secures the first end of the member to the second end of the member, or the two ends of the member may be permanently secured to each other using an adhesive or by being sewn together. Each of the buoyant float elements has a center aperture aligned along the center of a cross-section thereof. The member is preferably coupled to each of the buoyant float elements by being sequentially passed through the center apertures of each buoyant float element.
US11065176B2	Pressure field stimulation device Disclosed embodiments provide an improved stimulation device, including a cup and a driver. The cup has a cavity surrounded by a rim. In use, a user positions the rim such that an opening to the cavity is over an area to be stimulated (for example, the clitoris). A sealed- or substantially-sealed, chamber is formed by the cavity walls and the user's skin (surrounding the clitoris). A driver is configured to vary a volume of a cavity of a cup from a first volume to a second volume. The cup returns from the second volume to the first volume, in between intermittent varying from the first volume to the second volume, due to a buckle region wall of the cup springing out. The varying of the volume creates a pressure field in the chamber. The springing out produces a “thud” force, also used interchangeably with “thump” force.
US11065170B2	Smart medical rehabilitation device A smart medical rehabilitation device comprises a driving unit, a linkage unit, a sensing unit and a rehabilitation evaluating unit that are mounted on a frame, wherein the linkage unit comprises a link mechanism and a slide mechanism linked thereto so that the slide mechanism can be moved together with the link mechanism, wherein the slide mechanism is driven by the driving unit to slide along the groove plate, the link mechanism is linked to move with the slide mechanism thus the link mechanism moves to the corresponding position so that the slide mechanism can assist a training object in performing lower limb rehabilitation training, and the rehabilitation evaluating unit evaluates the physical status and rehabilitation status of the training object according to the physiological information and exercise information of the same collected by the sensing unit, and adjusts the exercise frequency and the exercise duration of the training object according to the physical status in real time.
US11065166B2	Motion-based power assist system for wheelchairs A motion-based push activation power assist system for manual wheelchairs. The system uses motion-based measurements to determine when the user applies a push to the wheelchair handrims and brakes with the handrims. The push recognition activates a drive system that provides an assistive driving force-pulse to the wheelchair to reduce the demand on the user during propulsion. The brake recognition deactivates the power assist. The provided power assist is proportional to the sensed push and can be modulated to different proportional settings.
US11065163B2	Feminine hygiene article with improved wings Feminine hygiene articles are disclosed herein. The feminine hygiene articles described herein can provide easily discernable placement and orientation guides which reduce the likelihood of misapplication by the user, facilitated attachment guides which can reduce the likelihood of misapplication of the feminine pad, and can also reduce the likelihood of improper attachment of the feminine pad to a panty. The feminine hygiene articles disclosed include uniquely shaped wings which can provide cues on proper attachment of the article to the panty, and may help in providing sustained coverage of the feminine hygiene article to the panty which reduces the likelihood that the pad will become detached during use.

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